The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y9R9-1", "A0A8V0YGN2-1" ], "evidence": [ { "id": "R-GGA-176059", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176059" } ] }, { "id": "R-GGA-5423653", "name": "MGST trimers transfer GS from GSH to AFXBO and AFNBO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y9R9-1", "A0A8V0YGN2-1" ], "evidence": [ { "id": "R-GGA-5423653", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5423653" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y9R9", "gene_name": "MGST3", "activity": [ { "ec_number": "4.4.1.20", "activity": "leukotriene C4 = leukotriene A4 + glutathione.", "evidence": [ { "id": "A0A8V0Y9R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R9" } ] }, { "ec_number": "4.4.1.20", "activity": "", "evidence": [ { "id": "A0A8V0Y9R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R9" } ] } ] }, { "uniprot_ac": "A0A8V0YGN2", "gene_name": "MGST1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0YGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0YGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN2" } ] } ] }, { "uniprot_ac": "A0A8V0Z0H3", "gene_name": "LTC4S", "activity": [ { "ec_number": "4.4.1.20", "activity": "leukotriene C4 = leukotriene A4 + glutathione.", "evidence": [ { "id": "A0A8V0Z0H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0H3" } ] }, { "ec_number": "4.4.1.20", "activity": "", "evidence": [ { "id": "A0A8V0Z0H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0H3" } ] } ] }, { "uniprot_ac": "E1C8L7", "gene_name": "LTC4SL", "activity": [ { "ec_number": "4.4.1.20", "activity": "leukotriene C4 = leukotriene A4 + glutathione.", "evidence": [ { "id": "E1C8L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ] }, { "ec_number": "4.4.1.20", "activity": "", "evidence": [ { "id": "E1C8L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8L7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.4.1.20", "ec_name": "leukotriene C4 = leukotriene A4 + glutathione.", "evidence": [ { "id": "4.4.1.20", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.4.1.20" }, { "id": "4.4.1.20", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.4.1.20" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCN3-1", "uniprot_ac": "A0A8V0YCN3", "uniprot_id": "A0A8V0YCN3_CHICK", "mass": { "chemical_mass": 49593.0, "monoisotopic_mass": 49593.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCN3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR34147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34147:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34147:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFYGALWGSMGLHGGLWGSMGLYGVLWGPTGVLWGPVGLYGALWGSMGLYGGLWGSMGVYGGLWGSMGLYGALWGSMGLYGGLWGSMGVYGGLWGSMGLYGALWGSMGVYGGLWALMGLYGALWGSMGLYGGLWGPMGVLWGLYGVLWGPMGSYGGSMGVMGLYGGLWGSMGLYGALWGSMGFYGGLWGSMGAYWGLYGVLWGSMGLYGGLWRSMGLYGGLCIPMGLYGVFMGALWGSMGLYGVLWGSMGLYGGLLGSYGALWGSMGFYGGLWGSMGSMGLYGGLWGSMGVLWGSMEVYGAYGGLWDSMGLYGALWGLMGFYGVLWGSMGAYGVLWGSMGVYGALWGSMGFYGALWGSMGLYGALWRLIGVLWGSMGVYGALWGSMHPYGALWGLYEVLWVPMGCYGVFMGVYGALWGSMGVYGGLWGSMGLYGVLWGSMGLYGGLWGSMGLHGGLWGSMGVYASLWGSMGSL", "length": 474, "header": "tr|A0A8V0YCN3-1|A0A8V0YCN3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCN3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y7N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3/entry#A0A8V0Y7N6-1", "sequence": { "sequence": "MGVYGALWGSVGLYGVLWGSMGLYGGLLGSLWGPMGAYGVLCALWGLNGDLWRPMGVYGGLWGSVGLYGGLWGSMGLYGVIWGFYGALWGSMGVYGGLWGSMGVYGGLWGSMGLYGALWGSMGVYGGLWALMGLYGALWGSMGLYGGLWGPMGVLWGLYGVLWGPMGSYGGSMGVMGLYGGLWGSMGLYGALWGSMGFYGGLWGSMGAYWGLYGVLWGSMGLYGGLWRSMGLYGGLCIPMGLYGVFMGALWGSMGLYGVLWGSMGLYGGLLGSYGALWGSMGFYG", "length": 285, "header": "tr|A0A8V0Y7N6-1|A0A8V0YCN3_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCN3-1" }, "locus": { "chromosome": "W", "start_pos": 359258, "end_pos": 357919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028922.1", "url": "https://www.ensembl.org/id/ENSGALT00010028922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016681.1", "url": "https://www.ensembl.org/id/ENSGALP00010016681.1" } ] } }, { "isoform_ac": "A0A8V0YCN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3/entry#A0A8V0YCN3-1", "sequence": { "sequence": "MGFYGALWGSMGLHGGLWGSMGLYGVLWGPTGVLWGPVGLYGALWGSMGLYGGLWGSMGVYGGLWGSMGLYGALWGSMGLYGGLWGSMGVYGGLWGSMGLYGALWGSMGVYGGLWALMGLYGALWGSMGLYGGLWGPMGVLWGLYGVLWGPMGSYGGSMGVMGLYGGLWGSMGLYGALWGSMGFYGGLWGSMGAYWGLYGVLWGSMGLYGGLWRSMGLYGGLCIPMGLYGVFMGALWGSMGLYGVLWGSMGLYGGLLGSYGALWGSMGFYGGLWGSMGSMGLYGGLWGSMGVLWGSMEVYGAYGGLWDSMGLYGALWGLMGFYGVLWGSMGAYGVLWGSMGVYGALWGSMGFYGALWGSMGLYGALWRLIGVLWGSMGVYGALWGSMHPYGALWGLYEVLWVPMGCYGVFMGVYGALWGSMGVYGGLWGSMGLYGVLWGSMGLYGGLWGSMGLHGGLWGSMGVYASLWGSMGSL", "length": 474, "header": "tr|A0A8V0YCN3-1|A0A8V0YCN3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCN3-1" }, "locus": { "chromosome": "W", "start_pos": 360960, "end_pos": 358234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028926.1", "url": "https://www.ensembl.org/id/ENSGALT00010028926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016685.1", "url": "https://www.ensembl.org/id/ENSGALP00010016685.1" } ] } }, { "isoform_ac": "A0A8V0YKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN3/entry#A0A8V0YKV5-1", "sequence": { "sequence": "MGLYGALWGLYGGLWGSMGLYGALWGSMGVYGILWGSMGLYGGLWGSMGFYGALWGLMGFYGGLWGSMGLCGGLWGSMGLYGALWGSMGLYGGLLGSYGAPWGSMGLYGGLCIPMGLYGVFMRSYGCLWGSMGSLWGSMGLYGALWGSMGVLWGSMGVYGALWGFMGFYGALWGFMGAYGVLMKAYGIIMGTLWGLMGSSGVLWGLLGFYGALWGSMGLYGGLWGSMGLYGGLWGSIGLYGVLWGTMGGYGVFMGLYGGLWGSIRSMGLHGALWGSMGGYGVLWGSMGLYGVLWRSMGSMGLYGALWGSMGVYGGLWGSMGSHKGLWALMGLYGSLWGSMGLYGGLWGSMGFYGALWGLMESYGVLWGLYVVLWGSMGLCGGLWGSMGPYG", "length": 391, "header": "tr|A0A8V0YKV5-1|A0A8V0YCN3_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCN3-1" }, "locus": { "chromosome": "W", "start_pos": 363539, "end_pos": 359404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028928.1", "url": "https://www.ensembl.org/id/ENSGALT00010028928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016687.1", "url": "https://www.ensembl.org/id/ENSGALP00010016687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9P7-1", "uniprot_ac": "A0A8V0Y9P7", "uniprot_id": "A0A8V0Y9P7_CHICK", "mass": { "chemical_mass": 125268.0, "monoisotopic_mass": 125268.0 }, "refseq": { "ac": "XP_040561197", "name": "tenascin-N isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561197" }, "gene_names": [ { "name": "TNN", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ] }, { "name": "TNN", "type": "synonym", "evidence": [ { "id": "XP_040561197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561197" } ] } ], "protein_names": [ { "name": "Tenascin N", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7/entry#names_and_taxonomy" } ] }, { "name": "tenascin-N isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040561197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561197" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040561197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561197" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7", "locus": { "chromosome": "8", "start_pos": 7074640, "end_pos": 7097673, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011095", "url": "https://www.ensembl.org/id/ENSGALG00010011095" } ] } } ], "crossref": [ { "id": "A0A8V0Y9P7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Y9P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424435", "url": "https://www.ncbi.nlm.nih.gov/gene/424435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EAPIDRY", "url": "https://omabrowser.org/oma/group/EAPIDRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y858", "url": "https://www.orthodb.org/?gene=A0A8V0Y858", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9P7", "url": "https://www.orthodb.org/?gene=A0A8V0Y9P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBW7", "url": "https://www.orthodb.org/?gene=A0A8V0YBW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGK8", "url": "https://www.orthodb.org/?gene=A0A8V0YGK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46708:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46708:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3000178", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040561197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040561197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y858", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y858", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y858-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y858-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFQSCFAFPIGILLCCALQASAIQLPASENCTSNGQRISFSHSYKIDLPTSSQIKVEADPLQHEGNSGVQLDPGEAEESEEQDIIFRHNIHVHAPKGSCETLAHVKDLLERMEKLEKEVAELREVCSPQKCCGGSQGVTHCSGHGMFLYETCSCKCAEGWEGSDCSRPTCPNLCSGHGRCDGGRCICDEPYFSEDCSQQLCPENCSGNGICDTAKGVCLCYEEFIGEDCSEKRCPGDCSGNGFCDTGECYCHEGFFGPDCSQVLAPQNLQLLNATEDSMAISWDQVTDVDNYLISYYPVGHETLEKQVHVPKEQLSYEITGLRPSTTYNVTLYHVKKGITSEPTHLEASTVPSALSAIWVTEEMEYSLEVEWENPPTNVDYYKLKFRSLVDVDEKQVMVPKSSDPKSRHIMTGLKPGMEYEVTVIPVKDDIEGKPSSVSGRTGIDSPTNVVTGRVTEDTATVSWNKVQAPIDRYMVRYTSADGDTKETEVGSENSIITLLNLKPGMEYTIHIWAEKGPHRSKKASTRALTGIDSPTKLLTDHVTENTITVSWNKVQALIDRYRVNYTSADGDTEEREVEKDENVTTLAGLKPGMEYVIHIWAEKGEQQSKRASTEAVTEIDSPTHLVTDQVTEDTVTISWDRVLALIDRYVVNYTSADGDTEEIEVAKNKTATTLVGLKPGTEYVIYLWAEKGVWQSKRTSTEAVTELDSPKNLVTDQVTEDSATISWDSVRAPIDRYIVSYTSADGGSKEIEVGKAKSTTTLTGLKAGMKYTIHLWAELGSMQSKKASTDALTEIDPPKNLRVSDVTQSTGVLTWTPPTAQIDGYTLTYQGQNGTSKEVQLGPREQQFVLEGLEQGTKYTVFVMAYKGDYQSRKTVGTFSTVSFLYPYPADCAQMQQNGNTSSGTYTIYLNGDGSRPMQVYCDMTTDGGGWIVFQRRSTGELDFYKRWKNYVEGFGDPTGEFWLGLDQLHNLTSSSPSHYELRVDLRTANESAYAVYDFFQVASSRERYRLSVGNYRGNAGDAMTYHNGWMFTTWDRDNDVALSNCALTHHGAWWYKNCHLANLNGKYGESKHSEGVNWEPWKGHEFSIPFTEMKIRPQSSSNESVLARKKRSLPGKRRKIRF", "length": 1125, "header": "tr|A0A8V0Y9P7-1|A0A8V0Y9P7_CHICK Isoform 1 of Tenascin N OS=Gallus gallus OX=9031 GN=TNN PE=3 SV=1 CANONICAL=A0A8V0Y9P7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y858-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7/entry#A0A8V0Y858-1", "sequence": { "sequence": "MDFQSCFAFPIGILLCCALQASAIQLPASENCTSNGQRISFSHSYKIDLPTSSQIKVEADPLQHEGNSGVQLDPGEAEESEEQDIIFRHNIHVHAPKGSCETLAHVKDLLERMEKLEKEVAELREVCSPQKCCGGSQGVTHCSGHGMFLYETCSCKCAEGWEGSDCSRPTCPNLCSGHGRCDGGRCICDEPYFSEDCSQQLCPENCSGNGICDTAKGVCLCYEEFIGEDCSEKRCPGDCSGNGFCDTGECYCHEGFFGPDCSQVLAPQNLQLLNATEDSMAISWDQVTDVDNYLISYYPVGHETLEKQVHVPKEQLSYEITGLRPSTTYNVTLYHTFPSDAIWVTEEMEYSLEVEWENPPTNVDYYKLKFRSLVDVDEKQVMVPKSSDPKSRHIMTGLKPGMEYEVTVIPVKDDIEGKPSSVSGRTGIDSPTKLLTDHVTENTITVSWNKVQALIDRYRVNYTSADGDTEEREVEKDENVTTLAGLKPGMEYVIHIWAEKGEQQSKRASTEAVTEIDSPTHLVTDQVTEDTVTISWDRVLALIDRYVVNYTSADGDTEEIEVAKNKTATTLVGLKPGTEYVIYLWAEKGVWQSKRTSTEAVTELDSPKNLVTDQVTEDSATISWDSVRAPIDRYIVSYTSADGGSKEIEVGKAKSTTTLTGLKAGMKYTIHLWAELGSMQSKKASTDALTEIDPPKNLRVSDVTQSTGVLTWTPPTAQIDGYTLTYQGQNGTSKEVQLGPREQQFVLEGLEQGTKYTVFVMAYKGDYQSRKTVGTFSTVSFLYPYPADCAQMQQNGNTSSGTYTIYLNGDGSRPMQVYCDMTTDGGGWIVFQRRSTGELDFYKRWKNYVEGFGDPTGEFWLGLDQLHNLTSSSPSHYELRVDLRTANESAYAVYDFFQVASSRERYRLSVGNYRGNAGDAMTYHNGWMFTTWDRDNDVALSNCALTHHGAWWYKNCHLANLNGKYGESKHSEGVNWEPWKGHEFSIPFTEMKIRPQSSSNESVLARKKRSLPGKRRKIRF", "length": 1020, "header": "tr|A0A8V0Y858-1|A0A8V0Y9P7_CHICK Computationally mapped isoform of Tenascin N OS=Gallus gallus OX=9031 GN=TNN PE=3 SV=1 CANONICAL=A0A8V0Y9P7-1" }, "locus": { "chromosome": "8", "start_pos": 7092183, "end_pos": 7074962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026563.1", "url": "https://www.ensembl.org/id/ENSGALT00010026563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015135.1", "url": "https://www.ensembl.org/id/ENSGALP00010015135.1" } ] } }, { "isoform_ac": "A0A8V0Y9P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7/entry#A0A8V0Y9P7-1", "sequence": { "sequence": "MDFQSCFAFPIGILLCCALQASAIQLPASENCTSNGQRISFSHSYKIDLPTSSQIKVEADPLQHEGNSGVQLDPGEAEESEEQDIIFRHNIHVHAPKGSCETLAHVKDLLERMEKLEKEVAELREVCSPQKCCGGSQGVTHCSGHGMFLYETCSCKCAEGWEGSDCSRPTCPNLCSGHGRCDGGRCICDEPYFSEDCSQQLCPENCSGNGICDTAKGVCLCYEEFIGEDCSEKRCPGDCSGNGFCDTGECYCHEGFFGPDCSQVLAPQNLQLLNATEDSMAISWDQVTDVDNYLISYYPVGHETLEKQVHVPKEQLSYEITGLRPSTTYNVTLYHVKKGITSEPTHLEASTVPSALSAIWVTEEMEYSLEVEWENPPTNVDYYKLKFRSLVDVDEKQVMVPKSSDPKSRHIMTGLKPGMEYEVTVIPVKDDIEGKPSSVSGRTGIDSPTNVVTGRVTEDTATVSWNKVQAPIDRYMVRYTSADGDTKETEVGSENSIITLLNLKPGMEYTIHIWAEKGPHRSKKASTRALTGIDSPTKLLTDHVTENTITVSWNKVQALIDRYRVNYTSADGDTEEREVEKDENVTTLAGLKPGMEYVIHIWAEKGEQQSKRASTEAVTEIDSPTHLVTDQVTEDTVTISWDRVLALIDRYVVNYTSADGDTEEIEVAKNKTATTLVGLKPGTEYVIYLWAEKGVWQSKRTSTEAVTELDSPKNLVTDQVTEDSATISWDSVRAPIDRYIVSYTSADGGSKEIEVGKAKSTTTLTGLKAGMKYTIHLWAELGSMQSKKASTDALTEIDPPKNLRVSDVTQSTGVLTWTPPTAQIDGYTLTYQGQNGTSKEVQLGPREQQFVLEGLEQGTKYTVFVMAYKGDYQSRKTVGTFSTVSFLYPYPADCAQMQQNGNTSSGTYTIYLNGDGSRPMQVYCDMTTDGGGWIVFQRRSTGELDFYKRWKNYVEGFGDPTGEFWLGLDQLHNLTSSSPSHYELRVDLRTANESAYAVYDFFQVASSRERYRLSVGNYRGNAGDAMTYHNGWMFTTWDRDNDVALSNCALTHHGAWWYKNCHLANLNGKYGESKHSEGVNWEPWKGHEFSIPFTEMKIRPQSSSNESVLARKKRSLPGKRRKIRF", "length": 1125, "header": "tr|A0A8V0Y9P7-1|A0A8V0Y9P7_CHICK Isoform 1 of Tenascin N OS=Gallus gallus OX=9031 GN=TNN PE=3 SV=1 CANONICAL=A0A8V0Y9P7-1" }, "locus": { "chromosome": "8", "start_pos": 7092183, "end_pos": 7074962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026554.1", "url": "https://www.ensembl.org/id/ENSGALT00010026554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015128.1", "url": "https://www.ensembl.org/id/ENSGALP00010015128.1" } ] } }, { "isoform_ac": "A0A8V0YBW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7/entry#A0A8V0YBW7-1", "sequence": { "sequence": "MDFQSCFAFPIGILLCCALQASAIQLPASENCTSNGQRISFSHSYKIDLPTSSQIKVEADPLQHEGNSGVQLDPGEAEESEEQDIIFRHNIHVHAPKGSCETLAHVKDLLERMEKLEKEVAELREVCSPQKCCGGSQGVTHCSGHGMFLYETCSCKCAEGWEGSDCSRPTCPNLCSGHGRCDGGRCICDEPYFSEDCSQQLCPENCSGNGICDTAKGVCLCYEEFIGEDCSEKRCPGDCSGNGFCDTGECYCHEGFFGPDCSQVLAPQNLQLLNATEDSMAISWDQVTDVDNYLISYYPVGHETLEKQVHVPKEQLSYEITGLRPSTTYNVTLYHVKKGITSEPTHLEASTVPSALSAIWVTEEMEYSLEVEWENPPTNVDYYKLKFRSLVDVDEKQVMVPKSSDPKSRHIMTGLKPGMEYEVTVIPVKDDIEGKPSSVSGRTGIDSPTNVVTGRVTEDTATVSWNKVQAPIDRYMVRYTSADGDTKETEVGSENSIITLLNLKPGMEYTIHIWAEKGPHRSKKASTRALTGIDSPTKLLTDHVTENTITVSWNKVQALIDRYRVNYTSADGDTEEREVEKDENVTTLAGLKPGMEYVIHIWAEKGEQQSKRASTEAVTEIDSPTHLVTDQVTEDTVTISWDRVLALIDRYVVNYTSADGDTEEIEVAKNKTATTLVGLKPGTEYVIYLWAEKGVWQSKRTSTEAVTEIDPPKNLRVSDVTQSTGVLTWTPPTAQIDGYTLTYQGQNGTSKEVQLGPREQQFVLEGLEQGTKYTVFVMAYKGDYQSRKTVGTFSTVSFLYPYPADCAQMQQNGNTSSGTYTIYLNGDGSRPMQVYCDMTTDGGGWIVFQRRSTGELDFYKRWKNYVEGFGDPTGEFWLGLDQLHNLTSSSPSHYELRVDLRTANESAYAVYDFFQVASSRERYRLSVGNYRGNAGDAMTYHNGWMFTTWDRDNDVALSNCALTHHGAWWYKNCHLANLNGKYGESKHSEGVNWEPWKGHEFSIPFTEMKIRPQSSSNESVLARKKRSLPGKRRKIRF", "length": 1037, "header": "tr|A0A8V0YBW7-1|A0A8V0YBW7_CHICK Computationally mapped isoform of Tenascin N OS=Gallus gallus OX=9031 GN=TNN PE=3 SV=1 CANONICAL=A0A8V0Y9P7-1" }, "locus": { "chromosome": "8", "start_pos": 7092183, "end_pos": 7074962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026555.1", "url": "https://www.ensembl.org/id/ENSGALT00010026555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015129.1", "url": "https://www.ensembl.org/id/ENSGALP00010015129.1" } ] } }, { "isoform_ac": "A0A8V0YGK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7/entry#A0A8V0YGK8-1", "sequence": { "sequence": "MDFQSCFAFPIGILLCCALQASAIQLPASENCTSNGQRISFSHSYKIDLPTSSQIKVEADPLQHEGNSGVQLDPGEAEESEEQDIIFRHNIHVHAPKGSCETLAHVKDLLERMEKLEKEVAELREVCSPQKCCGGSQGVTHCSGHGMFLYETCSCKCAEGWEGSDCSRPTCPNLCSGHGRCDGGRCICDEPYFSEDCSQQLCPENCSGNGICDTAKGVCLCYEEFIGEDCSEKRCPGDCSGNGFCDTGECYCHEGFFGPDCSQVLAPQNLQLLNATEDSMAISWDQVTDVDNYLISYYPVGHETLEKQVHVPKEQLSYEITGLRPSTTYNVTLYHVKKGITSEPTHLEASTVPSALSAIWVTEEMEYSLEVEWENPPTNVDYYKLKFRSLVDVDEKQVMVPKSSDPKSRHIMTGLKPGMEYEVTVIPVKDDIEGKPSSVSGRTGIDSPTNVVTGRVTEDTATVSWNKVQAPIDRYMVRYTSADGDTKETEVGSENSIITLLNLKPGMEYTIHIWAEKGPHRSKKASTRALTEIDSPTHLVTDQVTEDTVTISWDRVLALIDRYVVNYTSADGDTEEIEVAKNKTATTLVGLKPGTEYVIYLWAEKGVWQSKRTSTEAVTELDSPKNLVTDQVTEDSATISWDSVRAPIDRYIVSYTSADGGSKEIEVGKAKSTTTLTGLKAGMKYTIHLWAELGSMQSKKASTDALTEIDPPKNLRVSDVTQSTGVLTWTPPTAQIDGYTLTYQGQNGTSKEVQLGPREQQFVLEGLEQGTKYTVFVMAYKGDYQSRKTVGTFSTVSFLYPYPADCAQMQQNGNTSSGTYTIYLNGDGSRPMQVYCDMTTDGGGWIVFQRRSTGELDFYKRWKNYVEGFGDPTGEFWLGLDQLHNLTSSSPSHYELRVDLRTANESAYAVYDFFQVASSRERYRLSVGNYRGNAGDAMTYHNGWMFTTWDRDNDVALSNCALTHHGAWWYKNCHLANLNGKYGESKHSEGVNWEPWKGHEFSIPFTEMKIRPQSSSNESVLARKKRSLPGKRRKIRF", "length": 1037, "header": "tr|A0A8V0YGK8-1|A0A8V0Y9P7_CHICK Computationally mapped isoform of Tenascin N OS=Gallus gallus OX=9031 GN=TNN PE=3 SV=1 CANONICAL=A0A8V0Y9P7-1" }, "locus": { "chromosome": "8", "start_pos": 7092183, "end_pos": 7074962, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026559.1", "url": "https://www.ensembl.org/id/ENSGALT00010026559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015132.1", "url": "https://www.ensembl.org/id/ENSGALP00010015132.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3000178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "resource": "Reactome", "description": "ECM proteoglycans" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5XVA3-1", "protein_name": "Tenascin-N", "gene_name": "Tnn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLWGMLAFPLGFLLASALLVASAPANPETPGCSHKDQQVTVSHTYKIDVPKSALVQVETDPQSLSDDGTSLLVPGEDGEEQNIIFRHNIRLQTPQKNCELADSVQDLLARVKKLEEEMAELKEQCSTSRCCQGAADLSRHCSGHGTFFAETCSCHCDQGWEGADCEQPTCPGACSGHGRCVDGQCVCDQPYVGVDCAYAACPQDCSGHGVCVRGVCQCHKDFTAEDCSEQRCPGDCSGNGFCDTGECYCEMGFTGPDCSQVVAPQGLQLLKSTENSLLVSWEPSSEVDHYLLSYYPLGKEQATKQVRVPKEQHTYDITGLLPGTKYIVTLRNVKKDISSSPQHLLATTDLAVVGTAWVNEETETSLDVEWENPLTEVDYYKLRYGPLTGQEVTEVTVPKSRDPKSRYDITGLQPGTEYKITVVPIRGDLEGKPILLNGRTEIDGPTNVVTNQVTEDTASVSWDPVRADIDKYVVRYISHDGETKEKAVPKDQSSTVLTGLKPGEAYKVFVWAERGNQGSKKADTKALTEIDSPENLVTDRVTENSLSVSWDPVEAEIDRYVVSYTSVDGETKQVPVRKDQSSTVLTGLSPGVEYKVYVWAEKGDRESKKANTKAPTDIDSPKNLVTDQVTENTLSVSWDPVQANIDRYMVSYTSADGETREVPVPKEKSSTVLTGLRPGMEYKVHVWAQKGTQESRKANTKAPTDIDGPKNLVTDQVTETTLSVSWDPVEADIDRYMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQKGAQDSRKANTKAPTDIDSPKNLVTNQVTENTATISWDPVQADIDRYMVRYTSADGETREVPVRKEKSSTVLTGLRPGVEYTVQVWAQKGARESRKAKTKAPTEIDSPKNLVTNRVTENTATISWDPVRATIDRYMVRYTSADGETKEVPVSKDQSSTILTGLKPGMEYTIHVWAQKGARESKKADTKALTEIDPPKNFRPFGVTHSSGVLTWMPPSAQIDGYILTYQLPNGILKEVELQRGQQRFELQDLEQGVTYPVSLVAFKGNQRSRSVSTTLSTVDARFPHPSDCSQVQQNTNAAASGLYTIYLNGDASRPMQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTTTRYEVRADLQTANESAYAVYDFFQVASSKERYKLSVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGKYGETKHSEGVNWEPWKGHEFSIPYVELKIRPFGYSRDRFSGRKKRSIGGKARVF", "length": 1298 }, "evidence": [ { "id": "A0A8V0Y9P7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BB79-1", "protein_name": "Tenascin-N", "gene_name": "TNN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLQGRFCFPLVLLLGSVLLVTSAPATLESSGCSEKEQQVTVSHTYKIDVPKSALVQVEADPQPLRGDGTSLLAPEETEEQNIVFRHNIRLQTPQKDCELAGSVRDLLARVKKLEEEMAEVKERCSAQRCCPGAAGLSRHCSGHGTFSLDTCSCHCEHGWEGADCERLACPGACSGHGRCVDGRCVCEPPYVGADCAYPACPENCSGHGECVRGICQCHEDFISEDCSERRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVAPQGLQLLKSTEDSLLVSWEPSSQVDHYLLSYYPLGKELSVKQIKVPKEQHRYEILGLLPGTKYIVTLRNVKKDISSSPQHLLATTDLAVPGTAWVTDETENSLDVEWENPLTEVDYYKLQYGPLTGQEVAEVTVPKSGDPKSRYDITGLQPGTEYKITVIPMRGDLEGKPILLNGRTEIDSPTNVVTDRVTEDTVAVSWDPVRAVIDKYMVRYISADGETKDTAVPREQNSTVLTGLRPGEAYEVYVWAERGNQGSKKVDTTALTEIDSPQNLVTEQVTENTATVSWDPVQAVIDRYLVRYISADGDTREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESRKADTKAPTDIDSPQNLVTEQVTENTATVSWAPVQAVIDRYLVRYTSADGDSGEVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESRKADTKAPTDIDSPKNLVTEQVTENTATISWDPVQAVIDRYLVRYTSADGDTGEVPVGKEQSSTILTGLRPGVEYTVHVWAQNGDRESRKADTKAPTDIDSPQNLVTKQVTENTATVSWDPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESRKADTKAPTEIDSPQNLMTEQVTENTATVSWAPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESRKADTKAPTDIDPPQNLHPSAVTQSGGVLTWTPPSAEIDGYILTYQFPDGTVKEVQLGRGDQRFELQGLEQGVTLPVSLVAFKGDRRSRSVSTNLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDASRSLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPMKEFWLGLDKLHNLTMGTPTRYEVRVDLQTANESAYAVYDSFQVASSKERYRLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPFVELKIRPHGYSGEHVLSRKKRMLGENSRTF", "length": 1296 }, "evidence": [ { "id": "A0A8V0Y9P7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QSR3-1", "protein_name": "Tenascin-N isoform X1", "gene_name": "tnn", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVRLNRLKRGLFLLGTLFMVSHIVLSEEAVNAEKEVTFSHVYRIDSSCKQGSQVGQLSQDQASEGQLVTVNGENDIVFKHSIRLQPAGCGCADSEDFKALLYRVNGLEEEVNYLKSQCAQGCCKGGAGVDTSCSGHGTYQQDSCSCKCNPGWEGPDCSISSCPDECNDNGRCVDGRCVCYEGYTGHDCSQLTCPNDCKDKGHCVDGKCVCFSGFSGEDCSIATCPNDCIGNGRCVDGQCICDEGFFGIDCSMVLGPKGLRLIKVTDVSLLVEWESVRGAEYYILSYHPKGNKGAIKEVQVENTKNSYLITGLKPGVTYIVQVYAVIRGINSESDQITATTEVSGIEGIKVLSQTEDSIQVDWKNPGIIVDYFKLTHASHDGQGGHENVVMSQEARTKHTIVGLNPGTEYQIGVQAIKGENEGKASFATGVTDIDAPTNLATREVTENSATVTWDGVRAEIDGYMLTYSSAEGTSREIKVAAGATSYQLTSLKPGVLYTVFLWAYKGSRSSRKSMTEAETDIDAPTNLMTREVTEDSASVTWNKVQADIDGYMLKYSSLDGSGQEVRVGADSTSYRFTGLKPGVLYTVYVWAIKGARSSKKSSTEAETDIDAPTNLLTQEVTEDSASVTWNKVQADIDGYMLKYSSLDGSGQEVRVGADSISYRFTGLKPGVLYTVSVWAVKGSRSSRKATTEAETEIDAPKNLKATDVQTQTSTLTWKAPQANIEGYILTYRAEDGSMQTVEKTLTARENRFALSGLEMGKKYIVTLIAYRGSKRSKIVETTFSTVGLAYQFPMDCTQIMRNGNMESGVYTIYVNNNRSRTMQVYCDMKTDGGGWIVFQRRNTGKVDFMKKWRDYMKGFGELTEEFWLGLDKIHELTNTPTQYEARFDLGSGSDRKYAVYDNFKVAPSKQKFKLTIGSYKGNAGDAMTYHQGAPFSTVDSDNDIALGNCALTHQGAWWYKNCHLANLNGRFGDNRHSMGVNWEPWKGHLQSLDFAEIKIRPVGAAGRQKRSLKRRVAAY", "length": 1020 }, "evidence": [ { "id": "A0A8V0Y9P7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S708-1", "protein_name": "Tenascin-N", "gene_name": "TNN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLQEMFCFLLALLFGSVLLVASAPATLESPGCSNKEQQVTVSHTYKIDVPKSALVQVEADPQPLSDDGTSLLAPGETEEQNIIFRHNIRLQTPQKDCELAGSVQDLLARVKKLEEEMAEVKEQCSAQRCCPRAAGLSHHCSGHGTFSPVTCSCHCEQGWEGADCERPACPGACSGHGQCVDGRCLCEQPYVGIDCAYPACPENCSGHGACVRGVCQCHEDFTSEDCSERRCPGDCSGHGFCDTGECYCEEGFTGLDCSQVVAPQGLQLLKSTEDSLLVSWEPSSQVDHYLLSYYPLGKERSVKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKKEISSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKLQYGPLTGQEVAEVTVPKSSDPKSRYDITGLQPGTEYKITVVPMRGDLEGKPILLNGRTEIDSPTNVVTDQVTEDTAVVSWDPVRAVIDKYVVRYISADGETKDTAVPKEQSSTVLTGLKPGEAYEVYVWAERGSQESKKADTNALTEIDSPKNLVTDLVTENTATVSWDPVQADIDRYLVRYTSADGDTREVPVGKEKSSTVLTGLRPGVEYTVHVWAQKGDRESGKADTTAPTEIDSPKNLVTNQVTENTATVSWDPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGDRESGKADTMAPTDLDSPKNLVTTQVTENTATVSWDPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTILTGLRPGVEYTVHVWAQKGDRESGKADTTAPTDLDSPKNLVTTQVTENTATVSWDPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTILMGLRPGVEYTVHVWAQKGDRESRKADTTAPTDIDSPKNLVTTQVTENTATVSWDPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESRKADTTAPTDIDSPKNLVTTQVTENTATVSWDPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGDRESKKADTMAPTEIDSPQNLVTTRVTENTATVSWDPVQAVIDRYLVRYTSADGDTREVPVGKEQSSTVLMGLRPGVEYTVHVWAQKGDRESRKADTTALTDIDPPQNLRPSSVTQSSGVLTWKPPSAQIDGYILTYQFPDGTVKEVQLGRGDQRFELQGLEQGVTLPVSLVAFKGDRRSRSISTTLSTVGARFPHPSDCSQVQQNSNVASGLYTIYLHGDASRPLQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRTYVEGFGDPMKEFWLGLDKLHNLTTGTPTRYEVRVDLQTANESAFAIYDFFQVASSKERYRLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPFVELKIRPHGYSGEHVLGRKKRTLGESSRTF", "length": 1472 }, "evidence": [ { "id": "A0A8V0Y9P7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80Z71-1", "protein_name": "Tenascin-N", "gene_name": "Tnn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLWGMLAFPLGFLLASVLLVASAPATPESPGCSNKEQQVTVSHTYKIDVPKSALVQVETDPQSLSDDGTSLLAPGEDGEEQNIIFRHNIRLQTPQKNCDLADSVQDLLARMKKLEEEMAELKEQCNTNRCCQGAADLSRHCSGHGTFLPETCSCHCDQGWEGADCDQPTCPGACNGHGRCVDGQCVCDAPYVGVDCAYAACPQDCSGHGVCVQGVCQCHEDFTAEDCSEQRCPGDCSGNGFCDTGECYCEMGFTGPDCSQVVAPQGLQLLKSTENSLLVSWEPSSEVDYYLLSYYPLGKEQATKQVRVPKEQHTYDITGLLPGTKYIVTLRNVKKDISSSPQHLLATTDLAVVGTAWVNEETETSLDVEWENPLTEVDYYKLRYGPLTGQEVTEVTVPKSRDPKSRYDITGLQPGTEYKITVVPIRGDLEGKPILLNGRTEIDGPTNVVTNQVTEDTASVSWDPVRADIDKYVVRYIAPDGETKEKAVPKDQSSTVLTGLKPGEAYKVFVWAERGNQGSKKADTKALTEIDSPENLVTDRVTENSLSVSWDPVEADIDRYVVSYTSVDGETKQVPVKKDQRSTVLTGLSPGVEYKVYVWAEKGDRESKKANTKAPTDIDSPKNLVTDQVTENTLSVSWDPVQANIDRYMVSYTSADGETREVPVPKEKSSTVLTGLRPGVEYKVHVWAQKGTQESRKANTKAPTDIDGPKNLVTDQVTETTLSVSWDPVEADIDRYMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQKGAQDSRKANTKAPTDIDSPKNLVTEQVTESTATVSWDPVEADIDRYVVRYTSVDGETREFLVGKDQTSTVLTGMRPGVEYQVDVWAQKGTQESRKTSTKAPTDIDGPKNLVTDQVTETTLSVSWDPVEADIDRYMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQKGAQDSRKANTKAPTDIDSPKNLAIDQVTETTLSVSWDPVQADIDRYVVRYTSADGESKEFLIGKEQRSTVLTGLRPGVEYKVEVWAQKGARESKKANTEGHTDIDSPKNLVTNQVTENTATISWDPVQADIDRYMVRYTSADGETREIPVRKEKSSTVLTGLRPGVEYTVQVWAQKGARESKKAKTKAPTEIDSPKNLVTNRVTENTATISWDPVRANIDRYMVRYTSADGETKEIPVSKDQSSTILTGLKPGMEYTIHVWAQKGARESKKADTKALTEIDPPRNLRPFGVTHSGGVLTWLPPSAQIDGYILTYQFPNGTVKEVELPRGQQRFELQDLEQGVTYPVSLVAFKGNQRSRTVSTTLSTVDARFPHPSDCSQVQQNTNAASGLYTIYLNGDASRPMQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTTTRYEVRADLQTFNESAYAVYDFFQVASSKERYKLSVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGKYGETKHSEGVNWEPWKGHEFSIPYVELKIRPFGYSRDRFSGRKKRSIGKARMF", "length": 1560 }, "evidence": [ { "id": "A0A8V0Y9P7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UQP3-1", "protein_name": "Tenascin-N", "gene_name": "TNN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQEMFRFPMGLLLGSVLLVASAPATLEPPGCSNKEQQVTVSHTYKIDVPKSALVQVDADPQPLSDDGASLLALGEAREEQNIIFRHNIRLQTPQKDCELAGSVQDLLARVKKLEEEMVEMKEQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVELKIRPHGYSREPVLGRKKRTLRGRLRTF", "length": 1299 }, "evidence": [ { "id": "A0A8V0Y9P7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of sprouting angiogenesis", "id": "GO:1903672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "regulation of bone development", "id": "GO:1903010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "osteoblast development", "id": "GO:0002076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "neuron projection extension", "id": "GO:1990138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "regulation of smooth muscle tissue development", "id": "GO:1905899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1105, "end_pos": 1107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 902, "end_pos": 904, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" }, { "start_pos": 992, "end_pos": 994, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Y9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P7" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", 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"MHSLAQEIRSFSRANLRKQRTRVTTLTGRRVIETWRGACLQVEEEAEAVPGGGFVQDLSCDLQVGAARPWLLLGSQDAAHDLETLRKHKVTPQRVWHADLVWVLFFETKIFLSDSIPAAPSAGRWMSEGSARSWNMSLFHTADPTLPSVQASGTEHNQTYMPVGPKEGRQQFQGHPQLWCFYPPPSERGDNEAFRKLCETGSTLLWWLLLSQHQFPVNENNPSWPWLELSRGGRRPDLVSSAKHRYSLLRDPHTPVSSAGTSAAQM", "length": 266, "header": "tr|A0A8V0YC26-1|A0A8V0YC26_CHICK Isoform 1 of Dual specificity phosphatase 19 OS=Gallus gallus OX=9031 GN=DUSP19 PE=4 SV=1 CANONICAL=A0A8V0YC26-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26/entry#A0A8V0Y8B5-1", "sequence": { "sequence": "KRRPQGAGSRRGRPVRGARRQRAAERPCHALPRPGDQEFLQGQPAEAAHAGDDADGPEGHRDVAGRLPAGGGGGGSGTRRRLRAGPELRPAGSQDAAHDLETLRKHKVTHILNVAYGVQNAFLNDFVYKTISILDLPETDITSYFPECFEFIEKAKIQDGVVLVHCNAGVSRAAAIVIGFLMNSEGLSFASAFSLVKSARPSICPNPGFMEQLHKYQEQNIKANGSLSDHD", "length": 231, "header": "tr|A0A8V0Y8B5-1|A0A8V0YC26_CHICK Computationally mapped isoform of Dual specificity phosphatase 19 OS=Gallus gallus OX=9031 GN=DUSP19 PE=4 SV=1 CANONICAL=A0A8V0YC26-1" }, "locus": { "chromosome": "7", "start_pos": 2315725, "end_pos": 2310242, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026644.1", "url": "https://www.ensembl.org/id/ENSGALT00010026644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015195.1", "url": "https://www.ensembl.org/id/ENSGALP00010015195.1" } ] } }, { "isoform_ac": "A0A8V0YC26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26/entry#A0A8V0YC26-1", "sequence": { "sequence": "MHSLAQEIRSFSRANLRKQRTRVTTLTGRRVIETWRGACLQVEEEAEAVPGGGFVQDLSCDLQVGAARPWLLLGSQDAAHDLETLRKHKVTPQRVWHADLVWVLFFETKIFLSDSIPAAPSAGRWMSEGSARSWNMSLFHTADPTLPSVQASGTEHNQTYMPVGPKEGRQQFQGHPQLWCFYPPPSERGDNEAFRKLCETGSTLLWWLLLSQHQFPVNENNPSWPWLELSRGGRRPDLVSSAKHRYSLLRDPHTPVSSAGTSAAQM", "length": 266, "header": "tr|A0A8V0YC26-1|A0A8V0YC26_CHICK Isoform 1 of Dual specificity phosphatase 19 OS=Gallus gallus OX=9031 GN=DUSP19 PE=4 SV=1 CANONICAL=A0A8V0YC26-1" }, "locus": { "chromosome": "7", "start_pos": 2315640, "end_pos": 2314767, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026643.1", "url": "https://www.ensembl.org/id/ENSGALT00010026643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015194.1", "url": "https://www.ensembl.org/id/ENSGALP00010015194.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PI23-1", "F1P225-1", "A0A8V0XA98-1", "A0A8V0X472-1", "A0A8V0XI03-1", "A0A1D5P5S2-1", "A0A1D5PC43-1", "P0C597-1", "Q5F4B1-1", "Q6YI48-1", "Q90687-1", "Q98936-1", "Q9PW71-1", "A0A8V0YWD3-1", "A0A8V0Y719-1", "A0A8V0Z2T2-1", "A0A8V0Z920-1", "A0A8V0ZLS3-1", "A0A8V0YHN7-1", "A0A8V0X4H3-1", "Q5ZKG5-1", "Q9YH99-1", "Q9YHA0-1", "F1NCC5-1", "F1NAX3-1", "A0A8V0X8Q6-1", "A0A3Q2TZZ7-1", "A0A1D5NXI7-1", "A0A8V0YAF3-1", "A0A8V0XYX4-1", "A0A8V0YFZ7-1", "A0A8V0XVI4-1", "A0A8V0YFC8-1", "A0A8V0YAP9-1", "A0A8V0YVP7-1", "A0A8V0YIN5-1", "A0A8V0ZMU4-1", "A0A8V0ZPJ8-1", "F1NVR5-1", "A0A8V0ZVG8-1", "A0A8V0ZH43-1", "A0A8V0ZVC2-1", "A0A8V0ZQ53-1", "A0A1D5P6Q1-1", "Q9YH98-1", "A0A8V1A896-1", "A0A8V1AB05-1", "A0A3Q2UCN1-1", "A0A8V1A4B8-1", "A0A8V0ZJ28-1", "F1NWE3-1", "O13016-1", "Q9W6V5-1", "E1BRQ8-1", "A0A1D5P6X3-1", "A0A8V0XAP8-1", "A0A1D5PMZ4-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZXB3-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NXI7", "gene_name": "EYA4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5NXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXI7" } ] } ] }, { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5P6Q1", "gene_name": "PTPN21", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6Q1" } ] } ] }, { "uniprot_ac": "A0A1D5P6X3", "gene_name": "UBASH3B", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P6X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P6X3" } ] } ] }, { "uniprot_ac": "A0A1D5PC43", "gene_name": "EYA2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PC43" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A1D5PMZ4", "gene_name": "PTP4A3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PMZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMZ4" } ] } ] }, { "uniprot_ac": "A0A3Q2TZZ7", "gene_name": "PTPRF", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2TZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TZZ7" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X472", "gene_name": "PTPRM", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X472" } ] } ] }, { "uniprot_ac": "A0A8V0X4H3", "gene_name": "PTPN2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4H3" } ] } ] }, { "uniprot_ac": "A0A8V0X8Q6", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0X8Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8Q6" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XA98", "gene_name": "PTPRZ1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA98" } ] } ] }, { "uniprot_ac": "A0A8V0XAP8", "gene_name": "PTPN13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XAP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAP8" } ] } ] }, { "uniprot_ac": "A0A8V0XI03", "gene_name": "PTPRK", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI03" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XVI4", "gene_name": "LOC100858919", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XVI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVI4" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0Y719", "gene_name": "PTPN3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Y719", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y719" } ] } ] }, { "uniprot_ac": "A0A8V0YAF3", "gene_name": "PTPN12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF3" } ] } ] }, { "uniprot_ac": "A0A8V0YAP9", "gene_name": "EYA3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YAP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0YFC8", "gene_name": "PTPRC", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFC8" } ] } ] }, { "uniprot_ac": "A0A8V0YFZ7", "gene_name": "PTPRD", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFZ7" } ] } ] }, { "uniprot_ac": "A0A8V0YHN7", "gene_name": "PTPN1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YHN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN7" } ] } ] }, { "uniprot_ac": "A0A8V0YIN5", "gene_name": "PTPRB", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIN5" } ] } ] }, { "uniprot_ac": "A0A8V0YVP7", "gene_name": "PTPRU", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP7" } ] } ] }, { "uniprot_ac": "A0A8V0YWD3", "gene_name": "PTPRA", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YWD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWD3" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0Z920", "gene_name": "PTPN4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z920", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z920" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZH43", "gene_name": "PTPRG", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH43" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS3", "gene_name": "LOC419429", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZLS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZVC2", "gene_name": "PTPRJ", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC2" } ] } ] }, { "uniprot_ac": "A0A8V0ZVG8", "gene_name": "PTPRT", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A4B8", "gene_name": "PTPRVP", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4B8" } ] } ] }, { "uniprot_ac": "A0A8V1A6D3", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] } ] }, { "uniprot_ac": "A0A8V1A896", "gene_name": "CDC25A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A896", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A896" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB05", "gene_name": "PTPRS", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AB05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB05" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1AK42", "gene_name": "DUSP23", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] } ] }, { "uniprot_ac": "A0A8V1AKZ7", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] } ] }, { "uniprot_ac": "E1BVM8", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] } ] }, { "uniprot_ac": "E1BYA9", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NAX3", "gene_name": "PGP", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "F1NAX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAX3" } ] } ] }, { "uniprot_ac": "F1NC58", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9X2-1", "uniprot_ac": "A0A8V0Y9X2", "uniprot_id": "A0A8V0Y9X2_CHICK", "mass": { "chemical_mass": 103877.0, "monoisotopic_mass": 103877.0 }, "refseq": { "ac": "XP_015142733", "name": "FYVE, RhoGEF and PH domain-containing protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142733" }, "gene_names": [ { "name": "FGD4", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ] }, { "name": "FGD4", "type": "synonym", "evidence": [ { "id": "XP_015142733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142733" } ] } ], "protein_names": [ { "name": "FYVE, RhoGEF and PH domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2/entry#names_and_taxonomy" } ] }, { "name": "FYVE, RhoGEF and PH domain-containing protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015142733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142733" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015142733.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142733" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2", "locus": { "chromosome": "1", "start_pos": 59009368, "end_pos": 59116926, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011150", "url": "https://www.ensembl.org/id/ENSGALG00010011150" } ] } } ], "crossref": [ { "id": "A0A8V0Y9X2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Y9X2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012932", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012932", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13236", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13236", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107049013", "url": "https://www.ncbi.nlm.nih.gov/gene/107049013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107049013", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049013", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHPMFPP", "url": "https://omabrowser.org/oma/group/AHPMFPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P3P3", "url": "https://www.orthodb.org/?gene=A0A1D5P3P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8D0", "url": "https://www.orthodb.org/?gene=A0A8V0Y8D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9X2", "url": "https://www.orthodb.org/?gene=A0A8V0Y9X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673:SF98", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673:SF98", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015142733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142733", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P3P3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEPCGGSGPGEVFSQPRLGGGRGFTMSAGVRQALGRMSGADGINFRRAAIRRKSSPGLGPVPYGAALTRFAGVPRGEPARSSPAGSSICPKSLILSRSCPASATTRLVEQNVHNEAAQGINGSVPVKQSPRSASNPKPQVPPKPLHLQKLSPVTYQTSRHKALSSPKPRMEEDTPTPVSSVTKEKPSKVSDLIHRFEGCSPFSPIDLKKDSSALNVSKSQGRCGSTPPPQPKLLSQHPLLKQGNSNTDKTQVAQTHTANGVVAQDQVEREDRRILDRDSTVSTLVPDNSINSSLINGERVSTSRDSLETTASYEGSVLNSCYRTLSSDTLLPSDNEINTNVEEEPNEEIIKQDQPAETKETDEQKRHKIASELLQTEKAYVSRLGLLDQVFYSRLLEEANRGSFPAEVINKIFSNISSINAFHSKFLLPELEKRMQEWTTTPRIGDILQKLAPFLKMYGEYVKNFDNAMELVKTWTERSPQFKFIIQDIQKEKVCGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPQDSLDWKDAEKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERHLFLFNNMLLYCVPKFSLVGSKFSVRTRVGIDGMKIIETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQNTIEAFQQRNETFRNAIAKEYEDMPIEVSNAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGHVVCWKCSDYKAHLEYDGNKLNKVCKDCYHVIIGCTDSEEKKKKGILEIESAEVSGNSVICSFLQYMEKSKPWQKAWCVIPKQEAVVLYMYGAPQDVKALATIPLLGYTVDDTPRSADLPHSFKLTQSKSVHSFAADNEELKQKWLKVIHLAVKGETSECQNELQVSLEEQPESSKTSEC", "length": 927, "header": "tr|A0A8V0Y9X2-1|A0A8V0Y9X2_CHICK Isoform 1 of FYVE, RhoGEF and PH domain containing 4 OS=Gallus gallus OX=9031 GN=FGD4 PE=4 SV=1 CANONICAL=A0A8V0Y9X2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2/entry#A0A1D5P3P3-1", "sequence": { "sequence": "MLLGIFLGSSICPKSLILSRSCPASATTRLVEQNVHNEAAQGINGSVPVKQSPRSASNPKPQVPPKPLHLQKLSPVTYQTSRHKALSSPKPRMEEDTPTPVSSVTKEKPSKVSDLIHRFEGCSPFSPIDLKKDSSALNVSKSQGRCGSTPPPQPKLLSQHPLLKQGNSNTDKTQVAQTHTANGVVAQDQVEREDRRILDRDSTVSTLVPDNSINSSLINGERVSTSRDSLETTASYEGSVLNSCYRTLSSDTLLPSDNEINTNVEEEPNEEIIKQDQPAETKETDEQKRHKIASELLQTEKAYVSRLGLLDQVFYSRLLEEANRGSFPAEVINKIFSNISSINAFHSKFLLPELEKRMQEWTTTPRIGDILQKLAPFLKMYGEYVKNFDNAMELVKTWTERSPQFKFIIQDIQKEKVCGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPQDSLDWKDAEKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERHLFLFNNMLLYCVPKFSLVGSKFSVRTRVGIDGMKIIETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQNTIEAFQQRNETFRNAIAKEYEDMPIEVSNAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGHVVCWKCSDYKAHLEYDGNKLNKVCKDCYHVIIGCTDSEEKKKKGILEIESAEVSGNSVICSFLQYMEKSKPWQKAWCVIPKQEAVVLYMYGAPQDVKALATIPLLGYTVDDTPRSADLPHSFKLTQSKSVHSFAADNEELKQKWLKVIHLAVKGETSECQNELQVSLEEQPESSKTSEC", "length": 849, "header": "tr|A0A1D5P3P3-1|A0A1D5P3P3_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 4 OS=Gallus gallus OX=9031 GN=FGD4 PE=4 SV=2 CANONICAL=A0A8V0Y9X2-1" }, "locus": { "chromosome": "1", "start_pos": 59098416, "end_pos": 59010170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026668.1", "url": "https://www.ensembl.org/id/ENSGALT00010026668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015214.1", "url": "https://www.ensembl.org/id/ENSGALP00010015214.1" } ] } }, { "isoform_ac": "A0A8V0Y8D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2/entry#A0A8V0Y8D0-1", "sequence": { "sequence": "MLNLGNGKTNLNQIPRNPGNSLSSSWNFSLQGSSICPKSLILSRSCPASATTRLVEQNVHNEAAQGINGSVPVKQSPRSASNPKPQVPPKPLHLQKLSPVTYQTSRHKALSSPKPRMEEDTPTPVSSVTKEKPSKVSDLIHRFEGCSPFSPIDLKKDSSALNVSKSQGRCGSTPPPQPKLLSQHPLLKQGNSNTDKTQVAQTHTANGVVAQDQVEREDRRILDRDSTVSTLVPDNSINSSLINGERVSTSRDSLETTASYEGSVLNSCYRTLSSDTLLPSDNEINTNVEEEPNEEIIKQDQPAETKETDEQKRHKIASELLQTEKAYVSRLGLLDQVFYSRLLEEANRGSFPAEVINKIFSNISSINAFHSKFLLPELEKRMQEWTTTPRIGDILQKLAPFLKMYGEYVKNFDNAMELVKTWTERSPQFKFIIQDIQKEKVCGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPQDSLDWKDAEKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERHLFLFNNMLLYCVPKFSLVGSKFSVRTRVGIDGMKIIETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQNTIEAFQQRNETFRNAIAKEYEDMPIEVSNAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGHVVCWKCSDYKAHLEYDGNKLNKVCKDCYHVIIGCTDSEEKKKKGILEIESAEVSGNSVICSFLQYMEKSKPWQKAWCVIPKQEAVVLYMYGAPQDVKALATIPLLGYTVDDTPRSADLPHSFKLTQSKSVHSFAADNEELKQKWLKVIHLAVKGETSECQNELQVSLEEQPESSKTSEC", "length": 873, "header": "tr|A0A8V0Y8D0-1|A0A8V0Y9X2_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 4 OS=Gallus gallus OX=9031 GN=FGD4 PE=4 SV=1 CANONICAL=A0A8V0Y9X2-1" }, "locus": { "chromosome": "1", "start_pos": 59092238, "end_pos": 59010170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026663.1", "url": "https://www.ensembl.org/id/ENSGALT00010026663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015213.1", "url": "https://www.ensembl.org/id/ENSGALP00010015213.1" } ] } }, { "isoform_ac": "A0A8V0Y9X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2/entry#A0A8V0Y9X2-1", "sequence": { "sequence": "MGEPCGGSGPGEVFSQPRLGGGRGFTMSAGVRQALGRMSGADGINFRRAAIRRKSSPGLGPVPYGAALTRFAGVPRGEPARSSPAGSSICPKSLILSRSCPASATTRLVEQNVHNEAAQGINGSVPVKQSPRSASNPKPQVPPKPLHLQKLSPVTYQTSRHKALSSPKPRMEEDTPTPVSSVTKEKPSKVSDLIHRFEGCSPFSPIDLKKDSSALNVSKSQGRCGSTPPPQPKLLSQHPLLKQGNSNTDKTQVAQTHTANGVVAQDQVEREDRRILDRDSTVSTLVPDNSINSSLINGERVSTSRDSLETTASYEGSVLNSCYRTLSSDTLLPSDNEINTNVEEEPNEEIIKQDQPAETKETDEQKRHKIASELLQTEKAYVSRLGLLDQVFYSRLLEEANRGSFPAEVINKIFSNISSINAFHSKFLLPELEKRMQEWTTTPRIGDILQKLAPFLKMYGEYVKNFDNAMELVKTWTERSPQFKFIIQDIQKEKVCGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPQDSLDWKDAEKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERHLFLFNNMLLYCVPKFSLVGSKFSVRTRVGIDGMKIIETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQNTIEAFQQRNETFRNAIAKEYEDMPIEVSNAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGHVVCWKCSDYKAHLEYDGNKLNKVCKDCYHVIIGCTDSEEKKKKGILEIESAEVSGNSVICSFLQYMEKSKPWQKAWCVIPKQEAVVLYMYGAPQDVKALATIPLLGYTVDDTPRSADLPHSFKLTQSKSVHSFAADNEELKQKWLKVIHLAVKGETSECQNELQVSLEEQPESSKTSEC", "length": 927, "header": "tr|A0A8V0Y9X2-1|A0A8V0Y9X2_CHICK Isoform 1 of FYVE, RhoGEF and PH domain containing 4 OS=Gallus gallus OX=9031 GN=FGD4 PE=4 SV=1 CANONICAL=A0A8V0Y9X2-1" }, "locus": { "chromosome": "1", "start_pos": 59116727, "end_pos": 59010170, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026675.1", "url": "https://www.ensembl.org/id/ENSGALT00010026675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015216.1", "url": "https://www.ensembl.org/id/ENSGALP00010015216.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107049013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049013", "resource": "KEGG Pathway" }, { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "O88387-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 4", "gene_name": "Fgd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESNPAPTSCASKGKHSKVSDLISHFEGGSVLSSYTDVQKDSTMNLNIPQTPRQHGLTSTTPQKLPSHKSPQKQEKDSDQNQGQHGCLANGVAAAQSQMECETEKEAALSPETDTQTAAASPDAHVLNGVRNETTTDSASSVTNSHDENACDSSCRTQGTDLGLPSKEGEPVIEAELQERENGLSTEGLNPLDQHHEVKETNEQKLHKIATELLLTERAYVSRLNLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDAPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIMSGFAESEEKKRRGILEIESAEVSGNSEVCSFLQYMEKSKPWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYIVDDMPKSADLPHSFKLTQSKSVHSFAADSEELKQKWLKIILLAVTGETPDGPSEHLDTLDNLPGPKEKSEC", "length": 766 }, "evidence": [ { "id": "A0A8V0Y9X2", "url": "https://omabrowser.org/oma/group/A0A8V0Y9X2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91ZT5-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 4", "gene_name": "Fgd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEESNPAPTSCTSKGKHSKVSDLISHFEGGSVLSSYIDLQKDSTMNLNIPQTLGQPGLTSSPPRKFLPQHSPQKQENDPDQTQGQHGCLANGVVAAQNQMECEDEKETTLSPEMAIQTAAASPDTHVLNGERNETITDSASSIANSHDENASDSSCRTPGTDLGLPSKEGEPGMDAELQERENGVNTMGLDTLDQHHEVKETNEQKLHKIATELLLTERAYVSRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKTMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDSPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTFQISGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIISGFTDSEEKKRRGILEIESAEVSGNSEVCSFLQYMEKSKPWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDDMPKSADLPHSFKLTQSKSVHSFAADNEELKQKWLKIILLAVTGETPDGPSEHLATLNNLPGPKKKSEC", "length": 766 }, "evidence": [ { "id": "A0A8V0Y9X2", "url": "https://omabrowser.org/oma/group/A0A8V0Y9X2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96M96-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 4", "gene_name": "FGD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEIKPASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIAKDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEKSKPWQKAWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDEMPRSADLPHSFKLTQSKSVHSFAADSEELKQKWLKVILLAVTGETPGGPNEHPATLDDHPEPKKKSEC", "length": 766 }, "evidence": [ { "id": "A0A8V0Y9X2", "url": "https://omabrowser.org/oma/group/A0A8V0Y9X2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" }, { "name": "filopodium", "id": "GO:0030175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "filopodium assembly", "id": "GO:0046847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046847", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 687, "end_pos": 689 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA09-1", "uniprot_ac": "A0A8V0YA09", "uniprot_id": "A0A8V0YA09_CHICK", "mass": { "chemical_mass": 40250.0, "monoisotopic_mass": 40250.0 }, "refseq": {}, "gene_names": [ { "name": "PINX1", "type": "recommended", "evidence": [ { "id": "A0A8V0YA09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ] } ], "protein_names": [ { "name": "PIN2 (TERF1) interacting telomerase inhibitor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YA09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PINX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09", "locus": { "chromosome": "3", "start_pos": 106624077, "end_pos": 106686707, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011198", "url": "https://www.ensembl.org/id/ENSGALG00010011198" } ] } } ], "crossref": [ { "id": "A0A8V0YA09", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YA09", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8H5", "url": "https://www.orthodb.org/?gene=A0A8V0Y8H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA09", "url": "https://www.orthodb.org/?gene=A0A8V0YA09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23149:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23149:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y8H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMLAEPRRRQKWSVDPRNSAWSKDESKFGQRMLEKMGWSKGKGLGAQEQGNTEHIKVQVKNNMLGLGASIKYEDSWIAHQDDFNQLLAELNDCHGQGETVTNQKKTFNLEEKSKSSKKRVHYMKFAKGKDLSLRSEDDLSCIFGKRQKSMKTQDEATDAESQEEKHGGCWLAESTDNINTVKSVLTVQEYFAKRMAKLKGSQNEAETKLDGCCPTAEAALELSEELKTKAKKKKKKQKRDEAENTEQCEKPQGKKCKISSLNGKELDAPLYECHSRKKKRKHREQHDGESISCDENMGDGETCMGVSDGEDLSVEDSEAKQKKRHKKKHKKQKEETEECTEGTQRKKKKHCK", "length": 353, "header": "tr|A0A8V0YA09-1|A0A8V0YA09_CHICK Isoform 1 of PIN2 (TERF1) interacting telomerase inhibitor 1 OS=Gallus gallus OX=9031 GN=PINX1 PE=4 SV=1 CANONICAL=A0A8V0YA09-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09/entry#A0A8V0Y8H5-1", "sequence": { "sequence": "MAMLAEPRRRQKWSVDPRNSAWSKDESKFGQRMLEKMGWSKGKGLGAQEQGNTEHIKVQVKNNMLGLGASIKYEDSWIAHQDDFNQLLAELNDCHGQGETESSVTNQKKTFNLEEKSKSSKKRVHYMKFAKGKDLSLRSEDDLSCIFGKRQKSMKTQDEATDAESQEEKHGGCWLAESTDNINTVKSVLTVQEYFAKRMAKLKGSQNEAETKLDGCCPTAEAALELSEELKTKAKKKKKKQKRDEAENTEQCEKPQGKKCKISSLNGKELDAPLYECHSRKKKRKHREQHDGESISCDENMGRITNHQTRLPRATSSNGAFPHPDGAL", "length": 328, "header": "tr|A0A8V0Y8H5-1|A0A8V0YA09_CHICK Computationally mapped isoform of PIN2 (TERF1) interacting telomerase inhibitor 1 OS=Gallus gallus OX=9031 GN=PINX1 PE=4 SV=1 CANONICAL=A0A8V0YA09-1" }, "locus": { "chromosome": "3", "start_pos": 106686686, "end_pos": 106624134, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026757.1", "url": "https://www.ensembl.org/id/ENSGALT00010026757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015258.1", "url": "https://www.ensembl.org/id/ENSGALP00010015258.1" } ] } }, { "isoform_ac": "A0A8V0YA09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09/entry#A0A8V0YA09-1", "sequence": { "sequence": "MAMLAEPRRRQKWSVDPRNSAWSKDESKFGQRMLEKMGWSKGKGLGAQEQGNTEHIKVQVKNNMLGLGASIKYEDSWIAHQDDFNQLLAELNDCHGQGETVTNQKKTFNLEEKSKSSKKRVHYMKFAKGKDLSLRSEDDLSCIFGKRQKSMKTQDEATDAESQEEKHGGCWLAESTDNINTVKSVLTVQEYFAKRMAKLKGSQNEAETKLDGCCPTAEAALELSEELKTKAKKKKKKQKRDEAENTEQCEKPQGKKCKISSLNGKELDAPLYECHSRKKKRKHREQHDGESISCDENMGDGETCMGVSDGEDLSVEDSEAKQKKRHKKKHKKQKEETEECTEGTQRKKKKHCK", "length": 353, "header": "tr|A0A8V0YA09-1|A0A8V0YA09_CHICK Isoform 1 of PIN2 (TERF1) interacting telomerase inhibitor 1 OS=Gallus gallus OX=9031 GN=PINX1 PE=4 SV=1 CANONICAL=A0A8V0YA09-1" }, "locus": { "chromosome": "3", "start_pos": 106686686, "end_pos": 106626659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026755.1", "url": "https://www.ensembl.org/id/ENSGALT00010026755.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015256.1", "url": "https://www.ensembl.org/id/ENSGALP00010015256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ], "pmid": "" }, { "name": "telomerase RNA binding", "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ], "pmid": "" }, { "name": "protein localization to chromosome, telomeric region", "id": "GO:0070198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA09" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040553913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553913" } ] }, { "annotation": "Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4#function" }, { "database": "UniProtKB", "id": "ARBA00059023", "url": "https://www.uniprot.org/uniprotkb/ARBA00059023#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TDH", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422034", "url": "https://www.ncbi.nlm.nih.gov/gene/422034", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HWHASPR", "url": "https://omabrowser.org/oma/group/HWHASPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8P2", "url": "https://www.orthodb.org/?gene=A0A8V0Y8P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCE4", "url": "https://www.orthodb.org/?gene=A0A8V0YCE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42687:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42687:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040553913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040553913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13161", "url": "https://www.rhea-db.org/rhea/13161", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y8P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIVRNVSRAVSQLLQSPACGCGVSIVPVRCIGISPRQVASDASFHSVSFSESDHPRVLITGGLGQLGVGLAKLLRKRFGKNNVILSDIRKPADHVFYSGPFIYSDILDYKNLREIVVNNRITWLFHYSALLSAVGEANVPLARAVNITGLHNVLDIAAEHNLRLFVPSTIGAFGPTSPRDPTPDLCIQRPRTIYGVSKVHAELMGEYYHYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFHDAIKTGKFECNLKPDTRLPMMYIDDCLKATLEVMEAPAEALSMRTYNISAMSFTPEELAQEVQKHVPELQVTYNVDTVRQAIADSWPMNFDDSNARRDWGWKHDYDLPELVSTMFSFLGSDSRIAQAN", "length": 373, "header": "tr|A0A8V0YCE4-1|A0A8V0YCE4_CHICK Isoform 1 of L-threonine 3-dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=TDH PE=1 SV=1 CANONICAL=A0A8V0YCE4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4/entry#A0A8V0Y8P2-1", "sequence": { "sequence": "MPIVRNVSRAVSQLLQSPACGCGVSIVPVRCIGISPRQVASDASFHSVSFSESDHPRVLITGGLGQLGVGLAKLLRKRFGKNNVILSDIRKPADHVFYSGPFIYSDILDYKNLREIVVNNRITWLFHYSALLSAVGEANVPLARAVNITGLHNVLDIAAEHNLRLFVPSTIGAFGPTSPRDPTPDLCIQRPRTIYGVSKVHAELMGEYYHYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFHDAIKTGKFECNLKPDTRLPMMYIDDCLKATLEVMEAPAEALSMRTYNISAMSFTPEELAQEVQKHVPELQVTYNVDTVRQAIAVLKTCFIMFTFLKKASLKMFTTVVALVLFKCNIWPNGPAKLGLFIPSKNSLTLVLSSSMLKQECLPLNCDTDPSDEGL", "length": 406, "header": "tr|A0A8V0Y8P2-1|A0A8V0YCE4_CHICK Computationally mapped isoform of L-threonine 3-dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=TDH PE=1 SV=1 CANONICAL=A0A8V0YCE4-1" }, "locus": { "chromosome": "3", "start_pos": 106988594, "end_pos": 106979795, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026915.1", "url": "https://www.ensembl.org/id/ENSGALT00010026915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015330.1", "url": "https://www.ensembl.org/id/ENSGALP00010015330.1" } ] } }, { "isoform_ac": "A0A8V0YCE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4/entry#A0A8V0YCE4-1", "sequence": { "sequence": "MPIVRNVSRAVSQLLQSPACGCGVSIVPVRCIGISPRQVASDASFHSVSFSESDHPRVLITGGLGQLGVGLAKLLRKRFGKNNVILSDIRKPADHVFYSGPFIYSDILDYKNLREIVVNNRITWLFHYSALLSAVGEANVPLARAVNITGLHNVLDIAAEHNLRLFVPSTIGAFGPTSPRDPTPDLCIQRPRTIYGVSKVHAELMGEYYHYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFHDAIKTGKFECNLKPDTRLPMMYIDDCLKATLEVMEAPAEALSMRTYNISAMSFTPEELAQEVQKHVPELQVTYNVDTVRQAIADSWPMNFDDSNARRDWGWKHDYDLPELVSTMFSFLGSDSRIAQAN", "length": 373, "header": "tr|A0A8V0YCE4-1|A0A8V0YCE4_CHICK Isoform 1 of L-threonine 3-dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=TDH PE=1 SV=1 CANONICAL=A0A8V0YCE4-1" }, "locus": { "chromosome": "3", "start_pos": 106986596, "end_pos": 106979795, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026911.1", "url": "https://www.ensembl.org/id/ENSGALT00010026911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015329.1", "url": "https://www.ensembl.org/id/ENSGALP00010015329.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 183, "start_aa": "Thr", "end_pos": 183, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr183", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZN15-1", "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "gene_name": "Tdh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFLGMLKQVVSRTAQSKASSCRKLVLPWQFLGSSQHRVPANVNFHSTSFSEAEPPRVLITGGLGQLGVGLANLLRKRFGKDNVILSDIRKPPAHVFHSGPFIYANILDYKNLREIVVNHRISWLFHYSALLSAVGEANVPLARDVNITGLHNILDVAAEYNVRLFVPSTIGAFGPTSPRNPTPDLCVQRPRTIYGVSKVHTELMGEYYYYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFHAAAKNGTFECNLKASTRLPMMYISDCLRATLEVMEAPAECLSMRTYNINAMSFTPEELALALRKHAPDFQITYCVDPLRQAIAESWPMILDDSNARKDWGWKHDFDLPELVATMLSFHGVSTRVAQVN", "length": 373 }, "evidence": [ { "id": "A0A8V0YCE4", "url": "https://omabrowser.org/oma/group/A0A8V0YCE4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KIR8-1", "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "gene_name": "TDH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPVVRVLRRVACWMLQSPACGCRAPVLPSRFLGTSPRQIPMDANFHSTSFSEADQQRVLITGGLGQLGVGLASFLRKRFGKDNVILSDIRKPPEHVFLSGPFIYSDILDYKNLREIVVNNRITWLFHYSALLSAVGEANVSLARAVNITGLHNVLDVAAEHGLRLFVPSTIGAFGPTSPRNPTPDLCIQRPRTIYGVSKVHAELMGEYYYYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFHEAVKNGRFECNLKPDTRLPMMYIDDCLRATLEVMEAPAESLSMRTYNISAMSFTPEELAQEVLKHVPELQVTYNVDPVRQAIADSWPMNFDDSNARKDWGWKHDFDLPELVTTMLNFHGSESRVAQAN", "length": 373 }, "evidence": [ { "id": "A0A8V0YCE4", "url": "https://omabrowser.org/oma/group/A0A8V0YCE4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K3F7-1", "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "gene_name": "Tdh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFLGMLKQVVNGTAQSKASSCRKLVLPLKFLGTSQHRIPADANFHSTSISEAEPPRVLITGGLGQLGVGLANLLRKRFGKDNVILSDIRKPPAHVFHSGPFVYANILDYKSLREIVVNHRISWLFHYSALLSAVGEANVSLARDVNITGLHNVLDVAAEYNVRLFVPSTIGAFGPTSPRNPAPDLCIQRPRTIYGVSKVHTELMGEYYYYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFHAAAKNGTFECNLEAGTRLPMMYISDCLRATLEVMEAPAERLSMRTYNISAMSFTPEELAQALRKHAPDFQITYCVDPLRQAIAESWPMILDDSNARKDWGWKHDFDLPELVATMLNFHGVSTRVAQVN", "length": 373 }, "evidence": [ { "id": "A0A8V0YCE4", "url": "https://omabrowser.org/oma/group/A0A8V0YCE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MIR0-1", "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "gene_name": "TDH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPVVKMLKQVASRTLGSPACGCQPPTLPRRFLGTSPRQIPADANFHSTSFSEANQPRVLITGGLGQLGVGLASLLRKRFGKDNVILSDIRKPPEHVFLSGPFIYSDILDYKNLREIVVNNRVTWLFHYSALLSAVGEANVSLARAVNITGLHNVLDVAAEHGLRLFVPSTIGAFGPTSPRNPTPDLCIQRPRTIYGVSKVHAELMGEYYYYRYGLDFRCLRYPGIISADSQPGGGTTDYAVQIFQDAVKNGRFECNLNPGTKLPMMYIDDCLRATLEVMEAPAEALSLRTYNVNAMSFTPAELAQEVLKHIPEFQITYNVDSVRQAIADSWPMNFDDSTARRDWGWKHDFDLPELVTTMLNFHGAHSRVAQAN", "length": 373 }, "evidence": [ { "id": "A0A8V0YCE4", "url": "https://omabrowser.org/oma/group/A0A8V0YCE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9VPE8-1", "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "gene_name": "Tdh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRKCLASLALAPVASPIPLPRITPIASQLVQRRAFHQVPRESRPPKILITGGLGQLGIECAKLLRTQYGSQNVILSDIIKPSQSVLENGPYIFADILDFKGLQKIVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFVPSTIGAFGPDSPRNPTPNVTIQRPRTIYGVSKVHAELIGEYYYHKFGLDFRCLRFPGVISSDPPGGGTTDYAVAVFHEALRNGKYTCYLRPDTRLPMMYIEDCLRALLEFMRAPNEQLKRRVYNVTAMSFTPEELFAQLGKHVPNLHVTYKPDSRQLIADAWPQVFDDSDARRDWHWQHKYDLSNLVDFMIKDVQDNYINVQPEQQTLQI", "length": 367 }, "evidence": [ { "id": "A0A8V0YCE4", "url": "https://omabrowser.org/oma/group/A0A8V0YCE4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4" } ], "pmid": "" }, { "name": "L-threonine 3-dehydrogenase activity", "id": "GO:0008743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-threonine catabolic process", "id": "GO:0006567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13161", "name": "", "equation": "L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YCE4-1" ], "evidence": [ { "id": "13161", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13161" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YCE4", "gene_name": "TDH", "activity": [ { "ec_number": "1.1.1.103", "activity": "L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + NADH + H(+).", "evidence": [ { "id": "A0A8V0YCE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4" } ] }, { "ec_number": "1.1.1.103", "activity": "", "evidence": [ { "id": "A0A8V0YCE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE4" }, { "id": "PF01370", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAD-dependent epimerase/dehydratase", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 293, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.103", "ec_name": "L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + NADH + H(+).", "evidence": [ { "id": "1.1.1.103", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.103" }, { "id": "1.1.1.103", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.103" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 177, 183 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAB3-1", "uniprot_ac": "A0A8V0YAB3", "uniprot_id": "A0A8V0YAB3_CHICK", "mass": { "chemical_mass": 39916.0, "monoisotopic_mass": 39916.0 }, "refseq": { "ac": "XP_004939725", "name": "enoyl-CoA delta isomerase 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939725" }, "gene_names": [ { "name": "ECI2", "type": "recommended", "evidence": [ { "id": "A0A8V0YAB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ] }, { "name": "ECI2", "type": "synonym", "evidence": [ { "id": "XP_004939725", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939725" } ] } ], "protein_names": [ { "name": "Enoyl-CoA delta isomerase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YAB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3/entry#names_and_taxonomy" } ] }, { "name": "enoyl-CoA delta isomerase 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004939725", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939725" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004939725.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004939725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939725" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ECI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3", "locus": { "chromosome": "2", "start_pos": 65661369, "end_pos": 65631209, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011306", "url": "https://www.ensembl.org/id/ENSGALG00010011306" } ] } } ], "crossref": [ { "id": "A0A8V0YAB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00435", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00435", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420878", "url": "https://www.ncbi.nlm.nih.gov/gene/420878", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420878", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420878", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y8S2", "url": "https://www.orthodb.org/?gene=A0A8V0Y8S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAB3", "url": "https://www.orthodb.org/?gene=A0A8V0YAB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAB8", "url": "https://www.orthodb.org/?gene=A0A8V0YAB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCI0", "url": "https://www.orthodb.org/?gene=A0A8V0YCI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH69", "url": "https://www.orthodb.org/?gene=A0A8V0YH69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YH83", "url": "https://www.orthodb.org/?gene=A0A8V0YH83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00378", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00378", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-390247", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390247", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004939725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004939725", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8S2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YH83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YH83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVSQKDFEKAQEQLKLLKNDPGNETKLKLYALFKQATEGPCNSPKPGMLDFVKKAKWDAWNSLGSLSQDNARQEYTKLVSSLISAESAGRKKDTSPGESGHGGYETLIVTTDNNITKIMFNRPEKKNAINHKMYREIINALQEAAKDDSTIAVFTGNGDYYTSGNDLNNFSNVQPSEMKKMAKDAAELLKEFVGSFIDFPKPLIAVVNGPAVGISVTLLGLFDVVYASDRATFHTPFSQLGQSPEGCSSYLFPKIMGSAKANEILLFNKKLTASEACALGLVNEVFPDSTFQKEVWARLKAYASLPKNSLAVSKQLLRNIEKEKLHAVNSQECEVLTERWLSDECLNALVTFFQRKSKL", "length": 360, "header": "tr|A0A8V0YAB3-1|A0A8V0YAB3_CHICK Isoform 1 of Enoyl-CoA delta isomerase 2 OS=Gallus gallus OX=9031 GN=ECI2 PE=1 SV=1 CANONICAL=A0A8V0YAB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3/entry#A0A8V0Y8S2-1", "sequence": { "sequence": "MLLCTATIKKKTFIKKSNRQVQPVCSPSVHLHVTAATMQVSQKDFEKAQEQLKLLKNDPGNETKLKLYALFKQATEGPCNSPKPGMLDFVKKAKWDAWNSLGSLSQDNARQEYTKLVSSLISAESAGRKKDTSPGESGHGGYETLIVTTDNNITKIMFNRPEKKNAINHKMYREIINALQEAAKDDSTIAVFTGNGDYYTSGNDLNNFSNVQPSEMKKMAKDAAELLKEFVGSFIDFPKPLIAVVNGPAVGISVTLLGLFDVVYASDRATFHTPFSQLGQSPEGCSSYLFPKIMGSAKANEILLFNKKLTASEACALGLVNEVFPDSTFQKEVWARLKAYASLPKNSLAVSKQLLRNIEKEKLHAVNSQECEVLTERWLSDECLNALVTFFQRKSKL", "length": 397, "header": "tr|A0A8V0Y8S2-1|A0A8V0YAB3_CHICK Computationally mapped isoform of Enoyl-CoA delta isomerase 2 OS=Gallus gallus OX=9031 GN=ECI2 PE=1 SV=1 CANONICAL=A0A8V0YAB3-1" }, "locus": { "chromosome": "2", "start_pos": 65660583, "end_pos": 65641703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027001.1", "url": "https://www.ensembl.org/id/ENSGALT00010027001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015365.1", "url": "https://www.ensembl.org/id/ENSGALP00010015365.1" } ] } }, { "isoform_ac": "A0A8V0YAB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3/entry#A0A8V0YAB3-1", "sequence": { "sequence": "MQVSQKDFEKAQEQLKLLKNDPGNETKLKLYALFKQATEGPCNSPKPGMLDFVKKAKWDAWNSLGSLSQDNARQEYTKLVSSLISAESAGRKKDTSPGESGHGGYETLIVTTDNNITKIMFNRPEKKNAINHKMYREIINALQEAAKDDSTIAVFTGNGDYYTSGNDLNNFSNVQPSEMKKMAKDAAELLKEFVGSFIDFPKPLIAVVNGPAVGISVTLLGLFDVVYASDRATFHTPFSQLGQSPEGCSSYLFPKIMGSAKANEILLFNKKLTASEACALGLVNEVFPDSTFQKEVWARLKAYASLPKNSLAVSKQLLRNIEKEKLHAVNSQECEVLTERWLSDECLNALVTFFQRKSKL", "length": 360, "header": "tr|A0A8V0YAB3-1|A0A8V0YAB3_CHICK Isoform 1 of Enoyl-CoA delta isomerase 2 OS=Gallus gallus OX=9031 GN=ECI2 PE=1 SV=1 CANONICAL=A0A8V0YAB3-1" }, "locus": { "chromosome": "2", "start_pos": 65660583, "end_pos": 65647732, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027009.1", "url": "https://www.ensembl.org/id/ENSGALT00010027009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015373.1", "url": "https://www.ensembl.org/id/ENSGALP00010015373.1" } ] } }, { "isoform_ac": "A0A8V0YAB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3/entry#A0A8V0YAB8-1", "sequence": { "sequence": "MAASAPKFARGLCWRRICEISNRQVQPVCSPSVHLHVTAATMQVSQKDFEKAQEQLKLLKNDPGNETKLKLYALFKQATEGPCNSPKPGMLDFVKKAKWDAWNSLGSLSQDNARQEYTKLVSSLISAESAGRKKDTSPGESGHGGYETLIVTTDNNITKIMFNRPEKKNAINHKMYREIINALQEAAKDDSTIAVFTGNGDYYTSGNDLNNFSNVQPSEMKKMAKDAAELLKEFVGSFIDFPKPLIAVVNGPAVGISVTLLGLFDVVYASDRATFHTPFSQLGQSPEGCSSYLFPKIMGSAKANEILLFNKKLTASEACALGLVNEVFPDSTFQKEVWARLKAYASLPKNSLAVSKQLLRNIEKEKLHAVNSQECEVLTERWLSDECLNALVTFFQRKSKL", "length": 401, "header": "tr|A0A8V0YAB8-1|A0A8V0YAB8_CHICK Computationally mapped isoform of Enoyl-CoA delta isomerase 2 OS=Gallus gallus OX=9031 GN=ECI2 PE=1 SV=1 CANONICAL=A0A8V0YAB3-1" }, "locus": { "chromosome": "2", "start_pos": 65660583, "end_pos": 65631532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027020.1", "url": "https://www.ensembl.org/id/ENSGALT00010027020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015378.1", "url": "https://www.ensembl.org/id/ENSGALP00010015378.1" } ] } }, { "isoform_ac": "A0A8V0YCI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3/entry#A0A8V0YCI0-1", "sequence": { "sequence": "MLAGTATIKKKTFIKKSNRQVQPVCSPSVHLHVTAATMQVSQKDFEKAQEQLKLLKNDPGNETKLKLYALFKQATEGPCNSPKPGMLDFVKKAKWDAWNSLGSLSQDNARQEYTKLVSSLISAESAGRKKDTSPGESGHGGYETLIVTTDNNITKIMFNRPEKKNAINHKMYREIINALQEAAKDDSTIAVFTGNGDYYTSGNDLNNFSNVQPSEMKKMAKDAAELLKEFVGSFIDFPKPLIAVVNGPAVGISVTLLGLFDVVYASDRATFHTPFSQLGQSPEGCSSYLFPKIMGSAKANEILLFNKKLTASEACALGLVNEVFPDSTFQKEVWARLKAYASLPKNSLAVSKQLLRNIEKEKLHAVNSQECEVLTERWLSDECLNALVTFFQRKSKL", "length": 397, "header": "tr|A0A8V0YCI0-1|A0A8V0YCI0_CHICK Computationally mapped isoform of Enoyl-CoA delta isomerase 2 OS=Gallus gallus OX=9031 GN=ECI2 PE=1 SV=1 CANONICAL=A0A8V0YAB3-1" }, "locus": { "chromosome": "2", "start_pos": 65660583, "end_pos": 65640225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027005.1", "url": "https://www.ensembl.org/id/ENSGALT00010027005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015369.1", "url": "https://www.ensembl.org/id/ENSGALP00010015369.1" } ] } }, { "isoform_ac": "A0A8V0YH69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3/entry#A0A8V0YH69-1", "sequence": { "sequence": "MAGIGNFMATEGPCNSPKPGMLDFVKKAKWDAWNSLGSLSQDNARQEYTKLVSSLISAESAGRKKDTSPGESGHGGYETLIVTTDNNITKIMFNRPEKKNAINHKMYREIINALQEAAKDDSTIAVFTGNGDYYTSGNDLNNFSNVQPSEMKKMAKDAAELLKEFVGSFIDFPKPLIAVVNGPAVGISVTLLGLFDVVYASDRATFHTPFSQLGQSPEGCSSYLFPKIMGSAKANEILLFNKKLTASEACALGLVNEVFPDSTFQKEVWARLKAYASLPKNSLAVSKQLLRNIEKEKLHAVNSQECEVLTERWLSDECLNALVTFFQRKSKL", "length": 332, "header": "tr|A0A8V0YH69-1|A0A8V0YAB3_CHICK Computationally mapped isoform of Enoyl-CoA delta isomerase 2 OS=Gallus gallus OX=9031 GN=ECI2 PE=1 SV=1 CANONICAL=A0A8V0YAB3-1" }, "locus": { "chromosome": "2", "start_pos": 65660583, "end_pos": 65649205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026998.1", "url": "https://www.ensembl.org/id/ENSGALT00010026998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015362.1", "url": "https://www.ensembl.org/id/ENSGALP00010015362.1" } ] } }, { "isoform_ac": "A0A8V0YH83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3/entry#A0A8V0YH83-1", "sequence": { "sequence": "MPRGRRRPPGLEKEGGTEGGSGAVLSSSFLLTRQRVCPPSCHGGLGTEVCSGSVLASYLRDKATEGPCNSPKPGMLDFVKKAKWDAWNSLGSLSQDNARQEYTKLVSSLISAESAGRKKDTSPGESGHGGYETLIVTTDNNITKIMFNRPEKKNAINHKMYREIINALQEAAKDDSTIAVFTGNGDYYTSGNDLNNFSNVQPSEMKKMAKDAAELLKEFVGSFIDFPKPLIAVVNGPAVGISVTLLGLFDVVYASDRATFHTPFSQLGQSPEGCSSYLFPKIMGSAKANEILLFNKKLTASEACALGLVNEVFPDSTFQKEVWARLKAYASLPKNSLAVSKQLLRNIEKEKLHAVNSQECEVLTERWLSDECLNALVTFFQRKSKL", "length": 386, "header": "tr|A0A8V0YH83-1|A0A8V0YAB3_CHICK Computationally mapped isoform of Enoyl-CoA delta isomerase 2 OS=Gallus gallus OX=9031 GN=ECI2 PE=1 SV=1 CANONICAL=A0A8V0YAB3-1" }, "locus": { "chromosome": "2", "start_pos": 65660583, "end_pos": 65631408, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027016.1", "url": "https://www.ensembl.org/id/ENSGALT00010027016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015377.1", "url": "https://www.ensembl.org/id/ENSGALP00010015377.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420878", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420878", "resource": "KEGG Pathway" }, { "id": "R-GGA-390247", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390247", "resource": "Reactome", "description": "Beta-oxidation of very long chain fatty acids" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ], "pmid": "" }, { "name": "delta(3)-delta(2)-enoyl-CoA isomerase activity", "id": "GO:0004165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB3" }, { "id": "PS51228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACB", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 89, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 24, "end_pos": 26 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB70-1", "uniprot_ac": "A0A8V0YB70", "uniprot_id": "A0A8V0YB70_CHICK", "mass": { "chemical_mass": 74422.0, "monoisotopic_mass": 74422.0 }, "refseq": {}, "gene_names": [ { "name": "INTS9", "type": "recommended", "evidence": [ { "id": "A0A8V0YB70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 9", "type": "recommended", "evidence": [ { "id": "A0A8V0YB70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "common_name": 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"id": "PTHR46094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46094:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46094:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y8Y9", "url": 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"MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSKLPGLVLKDGSTFLDKELKECSGHVFVDSVPEFCLPETELLDLSTVDVILISNYHCMMALPYITEYTGFTGTVYATEPTVQIGRLLMEELVNSIERVPKAQSASTWKNKEVQRLLPAPLKDAVEVSMWRKCYTMPEVNAALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLAMTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFKQPCVIFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPSQSHRTDLMIDCQPPPMSYRRAEVLTLPYKRRYEKIEIMPELADSLVPLEIKPGISLATVSAMLHTKDNKHVLQLPPKPPQPPTSKKRKRVSDDVPECKPLKPLLSGSIPVDQFVQTLEKHGFSDVKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEPLRVKLRDLVHEGRKVKLCCSDAH", "length": 665, "header": "tr|A0A8V0YB70-1|A0A8V0YB70_CHICK Isoform 1 of Integrator complex subunit 9 OS=Gallus gallus OX=9031 GN=INTS9 PE=3 SV=1 CANONICAL=A0A8V0YB70-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70/entry#A0A8V0Y8Y9-1", "sequence": { "sequence": "MLDCGLDMTSTLNFLPLPLVQSPRLSKLPGLVLKDGSTFLDKELKECSGHVFVDSVPEFCLPETELLDLSTVDVILISNYHCMMALPYITEYTGFTGTVYATEPTVQIGRLLMEELVNSIERVPKAQSASTWKNKEVQRLLPAPLKDAVEVSMWRKCYTMPEVNAALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLAMTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFKQPCVIFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPSQSHRTDLMIDCQPPPMSYRRAEVLTLPYKRRYEKIEIMPELADSLVPLEIKPGISLATVSAMLHTKDNKHVLQLPPKPPQPPTSKKRKRVSDDVPECKPLKPLLSGSIPVDQFVQTLEKHGFSDVKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEPLRVKLRDLVLKFLQKF", "length": 634, "header": "tr|A0A8V0Y8Y9-1|A0A8V0YB70_CHICK Computationally mapped isoform of Integrator complex subunit 9 OS=Gallus gallus OX=9031 GN=INTS9 PE=3 SV=1 CANONICAL=A0A8V0YB70-1" }, "locus": { "chromosome": "3", "start_pos": 105892406, "end_pos": 105829421, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026255.1", "url": "https://www.ensembl.org/id/ENSGALT00010026255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014879.1", "url": "https://www.ensembl.org/id/ENSGALP00010014879.1" } ] } }, { "isoform_ac": "A0A8V0Y8Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70/entry#A0A8V0Y8Z4-1", "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSKLPGLVLKDGSTFLDKELKECSGHVFVDSVPEFCLPETELLDLSTVDVILISNYHCMMALPYITEYTGFTGTVYATEPTVQIGRLLMEELVNSIERVPKAQSASTWKNKEVQRLLPAPLKDAVEVSMWRKCYTMPEVNAALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLAMTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFKQPCVIFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPSQSHRTDLMIDCQPPPMSYRRAEVLTLPYKRRYEKIEIMPELADSLVPLEIKPGISLATVSAMLHTKDNKHVLQLPPKPPQPPTSKKRKRVSDDVPECKPLKPLLSGSIPVDQFVQTLEK", "length": 600, "header": "tr|A0A8V0Y8Z4-1|A0A8V0YB70_CHICK Computationally mapped isoform of Integrator complex subunit 9 OS=Gallus gallus OX=9031 GN=INTS9 PE=3 SV=1 CANONICAL=A0A8V0YB70-1" }, "locus": { "chromosome": "3", "start_pos": 105895858, "end_pos": 105830489, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026260.1", "url": "https://www.ensembl.org/id/ENSGALT00010026260.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014884.1", "url": "https://www.ensembl.org/id/ENSGALP00010014884.1" } ] } }, { "isoform_ac": "A0A8V0YB70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70/entry#A0A8V0YB70-1", "sequence": { "sequence": "MKLYCLSGHPTLPCNVLKFKSTTIMLDCGLDMTSTLNFLPLPLVQSPRLSKLPGLVLKDGSTFLDKELKECSGHVFVDSVPEFCLPETELLDLSTVDVILISNYHCMMALPYITEYTGFTGTVYATEPTVQIGRLLMEELVNSIERVPKAQSASTWKNKEVQRLLPAPLKDAVEVSMWRKCYTMPEVNAALSKIQLVGYSQKIELFGAVQVTPLSSGYALGSSNWIIQSHYEKVSYVSGSSLLTTHPQPMDQASLKNSDVLILTGLTQIPTANPDGMVGEFCSNLAMTVRNGGNVLVPCYPSGVIYDLLECLYQYIDSAGLSNVPFYFISPVANSSLEFSQIFAEWLCHNKQTKVYLPEPPFPHAELIQTNKLKHYPSIHGDFSNDFKQPCVIFTGHPSLRFGDVVHFMELWGKSSLNTVIFTEPDFSYLDALAPYQPLAMKCVYCPIDTRLNFIQVSKLLKEVQPLHVVCPEQYTQPPPSQSHRTDLMIDCQPPPMSYRRAEVLTLPYKRRYEKIEIMPELADSLVPLEIKPGISLATVSAMLHTKDNKHVLQLPPKPPQPPTSKKRKRVSDDVPECKPLKPLLSGSIPVDQFVQTLEKHGFSDVKVEDTAKGHIVLLQEAETLIQIEEDSTHIICDNDEPLRVKLRDLVHEGRKVKLCCSDAH", "length": 665, "header": "tr|A0A8V0YB70-1|A0A8V0YB70_CHICK Isoform 1 of Integrator complex subunit 9 OS=Gallus gallus OX=9031 GN=INTS9 PE=3 SV=1 CANONICAL=A0A8V0YB70-1" }, "locus": { "chromosome": "3", "start_pos": 105895858, "end_pos": 105827411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026261.1", "url": "https://www.ensembl.org/id/ENSGALT00010026261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014885.1", "url": "https://www.ensembl.org/id/ENSGALP00010014885.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway", "id": "GO:0090101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090101", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "regulation of cellular response to growth factor stimulus", "id": "GO:0090287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YB70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB70" }, { "id": "SM01027", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-Casp", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 433, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAS4-1", "uniprot_ac": "A0A8V0YAS4", "uniprot_id": "A0A8V0YAS4_CHICK", "mass": { "chemical_mass": 112078.0, "monoisotopic_mass": 112078.0 }, "refseq": { "ac": "XP_040560066", "name": "KAT8 regulatory NSL complex subunit 1-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560066" }, "gene_names": [ { "name": "KANSL1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YAS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4" } ] }, { "name": "KANSL1L", "type": "synonym", "evidence": [ { "id": "XP_040560066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560066" } ] } ], "protein_names": [ { "name": "KAT8 regulatory NSL complex subunit 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V0YAS4", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040560066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560066" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KANSL1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4", "locus": { "chromosome": "7", "start_pos": 2765845, "end_pos": 2823321, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011412", "url": "https://www.ensembl.org/id/ENSGALG00010011412" } ] } } ], "crossref": [ { "id": "A0A8V0YAS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "424004", "url": "https://www.ncbi.nlm.nih.gov/gene/424004", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424004", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424004", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRVVDIQ", "url": "https://omabrowser.org/oma/group/WRVVDIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y991", "url": "https://www.orthodb.org/?gene=A0A8V0Y991", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAS4", "url": "https://www.orthodb.org/?gene=A0A8V0YAS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHP3", "url": "https://www.orthodb.org/?gene=A0A8V0YHP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHP8", "url": "https://www.orthodb.org/?gene=A0A8V0YHP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22443:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22443:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15275", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15275", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040560066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560066", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y991", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y991-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPALREAATKGHGIHLSPSLSSRAMESDTTLCMENSRAVEEKIKEDSIARITCSVLGFPTAEPSLRNNIFSVQHFASPPSSKHYQSVLLMSTNSALSSKTGKQMKSGEPDCSRMRNALHNGADASFGQISHSGPEEQVKGEAFSETTSPNLAETQRLLDSNVTESGNAEEVQLLNDKWYKKNGFLGRALGVCAETIKGDLLHQILHGPSEGILSCAREEVYARLLQCVTKQQMEISRAKRTQKRLQMLLAKHVIKHCDQQLKCFVKHQFQRMKLLHKPARFSSSSSLRCADGWPENTAATLGSSSSADVQNGVCVAPGEIRGFALSAGGLLSRVEKDLDSDATCSSSDEDYDEQTVRTAVEASYTSEWKWLADRARIGSRWTWLQAQISELEYKIQQLTDLHRQIRATKGMVILEEFPFPKDILKKQIQLTDQEALLNATGNSQAAIERQDSLPEHDFEMSPSSPTLLLRNIEKQSAQLSEIISSLIAPLNLSPASALSSKTCRHRQLVNGISFRASDNREVSSSSSWLLDHQHIKKRRRDRTRLRSFSVTNVSTSARTRPLHSFQKRKLYRMHGACDWNPQTSSFRDTSCPYRTQLPCVVPPSALSSSEYSPESKMLDYVQELDSSFHPVLSFPSDIPLHIYFETLLRKDDVKGEPVDASYPGVEFKIAPENDYNHHNVALKRWNNSCLSNSKSQSVSGTSEQLSEGRKKRHLSETAVGERNTRFETFSFQHAEPESPSSFAAVTNINAMSRPTHSTSSQHNSRRRLRSESSYDIDNIVIPMSLVAPSKLEKLQYKEILTPSWRVVELEPLERSHADEEEAEDLSDEVFSSRHTKYEERERARWSLWEQSRWPRRNSRSYGKNADGRHGQDSVQKDHPGSSCASLHCAAEPVPDLTSEAHSSVCSGIAQLRRESQEAKSGLWELRVFPLKDEEVEALLCQDQITNQTEMSSAAFPSDSPCAPCTPIGLPDNGLPARKQSTEESEESENVCLGINSTRKQR", "length": 1002, "header": "tr|A0A8V0YAS4-1|A0A8V0YAS4_CHICK Isoform 1 of KAT8 regulatory NSL complex subunit 1 like OS=Gallus gallus OX=9031 GN=KANSL1L PE=4 SV=1 CANONICAL=A0A8V0YAS4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y991-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4/entry#A0A8V0Y991-1", "sequence": { "sequence": "MTPALREAATKGHGIHLSPSLSSRAMESDTTLCMENSRAVEEKIKEDSIARITCSVLGFPTAEPSLRNNIFSVQHFASPPSSKHYQSVLLMSTNSALSSKTGKQMKSGEPDCSRMRNALHNGADASFGQISHSGPEEQVKGEAFSETTSPNLAETQRLLDSNVTESGNAEEVQLLNDKWYKKNGFLGRALGVCAETIKGDLLHQILHGPSEGILSCAREEVYARLLQCVTKQQMEISRAKRTQKRLQMLLAKHVIKHCDQQLKCFVKHQFQRMKLLHKPARFSSSSSLRCADGWPENTAATLGSSSSADVQNGVCVAPGEIRGFALSAGGLLSRVEKDLDSDATCSSSDEDYDEQTVRTAVEASYTSEWKWLADRARIGSRWTWLQAQISELEYKIQQLTDLHRQIRATKSAQLSEIISSLIAPLNLSPASALSSKTCRHRQLVNGISFRASDNREVSSSSSWLLDHQHIKKRRRDRTRLRSFSVTNVSTSARTRPLHSFQKRKLYRMHGACDWNPQTSSFRDTSCPYRTQLPCVVPPSALSSSEYSPESKMLDYVQELDSSFHPVLSFPSDIPLHIYFETLLRKDDVKGEPVDASYPGVEFKIAPENDYNHHNVALKRWNNSCLSNSKSQSVSGTSEQLSEGRKKRHLSETAVGERNTRFETFSFQHAEPESPSSFAAVTNINAMSRPTHSTSSQHNSRRRLRSESSYDIDNIVIPMSLVAPSKLEKLQYKEILTPSWRVVELEPLERSHADEEEAEDLSDEVFSSRHTKYEERERARWSLWEQSRWPRRNSRSYGKNADGRHGQDSVQKDHPGSSCASLHCAAEPVPDLTSEAHSSVCSGIAQLRRESQEAKSGLWELRVFPLKDEEVEALLCQDQITNQTEMSSAAFPSDSPCAPCTPIGLPDNGLPARKQSTEESEESENVCLGINSTRKQR", "length": 936, "header": "tr|A0A8V0Y991-1|A0A8V0YAS4_CHICK Computationally mapped isoform of KAT8 regulatory NSL complex subunit 1 like OS=Gallus gallus OX=9031 GN=KANSL1L PE=4 SV=1 CANONICAL=A0A8V0YAS4-1" }, "locus": { "chromosome": "7", "start_pos": 2818815, "end_pos": 2767384, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027286.1", "url": "https://www.ensembl.org/id/ENSGALT00010027286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015540.1", "url": "https://www.ensembl.org/id/ENSGALP00010015540.1" } ] } }, { "isoform_ac": "A0A8V0YAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4/entry#A0A8V0YAS4-1", "sequence": { "sequence": "MTPALREAATKGHGIHLSPSLSSRAMESDTTLCMENSRAVEEKIKEDSIARITCSVLGFPTAEPSLRNNIFSVQHFASPPSSKHYQSVLLMSTNSALSSKTGKQMKSGEPDCSRMRNALHNGADASFGQISHSGPEEQVKGEAFSETTSPNLAETQRLLDSNVTESGNAEEVQLLNDKWYKKNGFLGRALGVCAETIKGDLLHQILHGPSEGILSCAREEVYARLLQCVTKQQMEISRAKRTQKRLQMLLAKHVIKHCDQQLKCFVKHQFQRMKLLHKPARFSSSSSLRCADGWPENTAATLGSSSSADVQNGVCVAPGEIRGFALSAGGLLSRVEKDLDSDATCSSSDEDYDEQTVRTAVEASYTSEWKWLADRARIGSRWTWLQAQISELEYKIQQLTDLHRQIRATKGMVILEEFPFPKDILKKQIQLTDQEALLNATGNSQAAIERQDSLPEHDFEMSPSSPTLLLRNIEKQSAQLSEIISSLIAPLNLSPASALSSKTCRHRQLVNGISFRASDNREVSSSSSWLLDHQHIKKRRRDRTRLRSFSVTNVSTSARTRPLHSFQKRKLYRMHGACDWNPQTSSFRDTSCPYRTQLPCVVPPSALSSSEYSPESKMLDYVQELDSSFHPVLSFPSDIPLHIYFETLLRKDDVKGEPVDASYPGVEFKIAPENDYNHHNVALKRWNNSCLSNSKSQSVSGTSEQLSEGRKKRHLSETAVGERNTRFETFSFQHAEPESPSSFAAVTNINAMSRPTHSTSSQHNSRRRLRSESSYDIDNIVIPMSLVAPSKLEKLQYKEILTPSWRVVELEPLERSHADEEEAEDLSDEVFSSRHTKYEERERARWSLWEQSRWPRRNSRSYGKNADGRHGQDSVQKDHPGSSCASLHCAAEPVPDLTSEAHSSVCSGIAQLRRESQEAKSGLWELRVFPLKDEEVEALLCQDQITNQTEMSSAAFPSDSPCAPCTPIGLPDNGLPARKQSTEESEESENVCLGINSTRKQR", "length": 1002, "header": "tr|A0A8V0YAS4-1|A0A8V0YAS4_CHICK Isoform 1 of KAT8 regulatory NSL complex subunit 1 like OS=Gallus gallus OX=9031 GN=KANSL1L PE=4 SV=1 CANONICAL=A0A8V0YAS4-1" }, "locus": { "chromosome": "7", "start_pos": 2818815, "end_pos": 2767384, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027284.1", "url": "https://www.ensembl.org/id/ENSGALT00010027284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015538.1", "url": "https://www.ensembl.org/id/ENSGALP00010015538.1" } ] } }, { "isoform_ac": "A0A8V0YHP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4/entry#A0A8V0YHP3-1", "sequence": { "sequence": "MISSVEEQSQVCCKLPTVAIMTPALREAATKGHGIHLSPSLSSRAMESDTTLCMENSRAVEEKIKEDSIARITCSVLGFPTAEPSLRNNIFSVQHFASPPSSKHYQSVLLMSTNSALSSKTGKQMKSGEPDCSRMRNALHNGADASFGQISHSGPEEQVKGEAFSETTSPNLAETQRLLDSNVTESGNAEEVQLLNDKWYKKNGFLGRALGVCAETIKGDLLHQILHGPSEGILSCAREEVYARLLQCVTKQQMEISRAKRTQKRLQMLLAKHVIKHCDQQLKCFVKHQFQRMKLLHKPARFSSSSSLRCADGWPENTAATLGSSSSADVQNGVCVAPGEIRGFALSAGGLLSRVEKDLDSDATCSSSDEDYDEQTVRTAVEASYTSEWKWLADRARIGSRWTWLQAQISELEYKIQQLTDLHRQIRATKGMVILEEFPFPKDILKKQIQLTDQEALLNATGNSQAAIERQDSLPEHDFEMSPSSPTLLLRNIEKQSAQLSEIISSLIAPLNLSPASALSSKTCRHRQLVNGISFRASDNREVSSSSSWLLDHQHIKKRRRDRTRLRSFSVTNVSTSARTRPLHSFQKRKLYRMHGACDWNPQTSSFRDTSCPYRTQLPCVVPPSALSSSEYSPESKMLDYVQELDSSFHPVLSFPSDIPLHIYFETLLRKDDVKGEPVDASYPGVEFKIAPENVSGTSEQLSEGRKKRHLSETAVGERNTRFETFSFQHAEPESPSSFAAVTNINAMSRPTHSTSSQHNSRRRLRSESSYDIDNIVIPMSLVAPSKLEKLQYKEILTPSWRVVELEPLERSHADEEEAEDLSDEVFSSRHTKYEERERARWSLWEQSRWPRRNSRSYGKNADGRHGQDSVQKDHPGSSCASLHCAAEPVPDLTSEAHSSVCSGIAQLRRESQEAKSGLWELRVFPLKDEEVEALLCQDQITNQTEMSSAAFPSDSPCAPCTPIGLPDNGLPARKQSTEESEESENVCLGINSTRKQR", "length": 998, "header": "tr|A0A8V0YHP3-1|A0A8V0YAS4_CHICK Computationally mapped isoform of KAT8 regulatory NSL complex subunit 1 like OS=Gallus gallus OX=9031 GN=KANSL1L PE=4 SV=1 CANONICAL=A0A8V0YAS4-1" }, "locus": { "chromosome": "7", "start_pos": 2822234, "end_pos": 2767384, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027283.1", "url": "https://www.ensembl.org/id/ENSGALT00010027283.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015537.1", "url": "https://www.ensembl.org/id/ENSGALP00010015537.1" } ] } }, { "isoform_ac": "A0A8V0YHP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4/entry#A0A8V0YHP8-1", "sequence": { "sequence": "MTPALREAATKGHGIHLSPSLSSRAMESDTTLCMENSRAVEEKIKEDSIARITCSVLGFPTAEPSLRNNIFSVQHFASPPSSKHYQSVLLMSTNSALSSKTGKQMKSGEPDCSRMRNALHNGADASFGQISHSGPEEQVKGEAFSETTSPNLAETQRLLDSNVTESGNAEEVQLLNDKWYKKNGFLGRALGVCAETIKGDLLHQILHGPSEGILSCAREEVYARLLQCVTKQQMEISRAKRTQKRLQMLLAKHVIKHCDQQLKCFVKHQFQRMKLLHKPARFSSSSSLRCADGWPENTAATLGSSSSADVQNGVCVAPGEIRGFALSAGGLLSRVEKDLDSDATCSSSDEDYDEQTVRTAVEAYTSEWKWLADRARIGSRWTWLQAQISELEYKIQQLTDLHRQIRATKGMVILEEFPFPKDILKKQIQLTDQEALLNATGNSQAAIERQDSLPEHDFEMSPSSPTLLLRNIEKQSAQLSEIISSLIAPLNLSPASALSSKTCRHRQLVNGISFRASDNREVSSSSSWLLDHQHIKKRRRDRTRLRSFSVTNVSTSARTRPLHSFQKRKLYRMHGACDWNPQTSSFRDTSCPYRTQLPCVVPPSALSSSEYSPESKMLDYVQELDSSFHPVLSFPSDIPLHIYFETLLRKDDVKGEPVDASYPGVEFKIAPENDYNHHNVALKRWNNSCLSNSKSQSVSGTSEQLSEGRKKRHLSETAVGERNTRFETFSFQHAEPESPSSFAAVTNINAMSRPTHSTSSQHNSRRRLRSESSYDIDNIVIPMSLVAPSKLEKLQYKEILTPSWRVVELEPLERSHADEEEAEDLSDEVFSSRHTKYEERERARWSLWEQSRWPRRNSRSYGKNADGRHGQDSVQKDHPGSSCASLHCAAEPVPDLTSEAHSSVCSGIAQLRRESQEAKSGLWELRVFPLKDEEVEALLCQDQITNQTEMSSAAFPSDSPCAPCTPIGLPDNGLPARKQSTEESEESENVCLGINSTRKQR", "length": 1001, "header": "tr|A0A8V0YHP8-1|A0A8V0YAS4_CHICK Computationally mapped isoform of KAT8 regulatory NSL complex subunit 1 like OS=Gallus gallus OX=9031 GN=KANSL1L PE=4 SV=1 CANONICAL=A0A8V0YAS4-1" }, "locus": { "chromosome": "7", "start_pos": 2818815, "end_pos": 2767384, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027288.1", "url": "https://www.ensembl.org/id/ENSGALT00010027288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015542.1", "url": "https://www.ensembl.org/id/ENSGALP00010015542.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424004", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424004", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MSM6-1", "protein_name": "KAT8 regulatory NSL complex subunit 1-like protein isoform X1", "gene_name": "Kansl1l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTPALKEATTKGICFSSLPSAMESDKMLCVESPRTVDEKLTAGDTLSQMLGFPTPEPTLNTNFVNLKHFASPQASKHFQTVLLMSSNSTLNKYNENYNQKKGVESNCCKLKNVLCNGSSIQLSKICHSHSEKEFIKKELSDTTSQCMKDIQIVLDSNLTKDTNVDKIHLQNCKWYPKNALLDKFTDTKIKKGLLQCTQKKIGPSHSDMPISSSAAEKEEEVNARLLHCVSKQKILLSQARRTQKHLQMLLAKHVVQHYGQQMKFSMKHQLPTMKLFHEPTTVLGNSLLEHSEIKPEVNILASENKFWDDTNNGFAQCTAAEIQRFALSATGLLSHVEVGLDSDATDSSSDDELDEYTIRKNVAVNSSTEWKWLVDRAQVGSRWTWLQAQISELEYKIQQLTDIHRHIRASKGIVILEECPLPKDILKKQIQFSNQAVSLNTSVNSQVPQRGEEPLPEHDFEMSPSSPTLLLRNIEKQSAQLTEIINSLIAPLNLSPTSSPLSSKSCSHKCLANGISRSASENLDELSSSSSWLLNQKHSKKRRKDRTRLKSPSLAIMSTAARTRPLQSFHKRKLYRLSPTFYWTPQTLPSKEAFLNATQIPYMGSPLSWDNWEQSSNSQLLREHVSKLDSSFHPVLSLPSEMPLHLHFETLFKKTDVKGELAENPFVGDCIIAPPPVQGTSLNQWRNGYSPICKPQIRSQSSAQLLQGRKKRHLSETALAGERTRFEDFAFQRTEPGSHCDFTAVSNANVTSRTQNSSSQNTARRRLRSESSYDIDNIVIPMSLVAPAKLEKLQYKEILTPRWRMVVLQPLDEHNLSKEEIEDLSDEVFSLRHKKYEEREQARWSLWEQSKWHRRNNRAYSKNAEAQDLVLKENPGELSSAQQCVAESPLELLADNTSLYAQDSLSLNDSQEIKSLRWERRAFPLKDEDTAALLCQDERKDQTEGASTAFHDEVFCSTTPENGHPPKMQLDGMEEYKTFAIGVTNVKRNR", "length": 990 }, "evidence": [ { "id": "A0A8V0YAS4", "url": "https://omabrowser.org/oma/group/A0A8V0YAS4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9TIT8-1", "protein_name": "KAT8 regulatory NSL complex subunit 1 like", "gene_name": "KANSL1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTPALREAATKGICFSSLPNTMESDKMLCMESPRTVDEKLKGDTFSQMLGFPTSEPTLNTNFVNLKHFGSPQSSKHYQTVLLMSSNTTLNKYNENYKQKKLGEPNCNKLKNILCNGGSIQLSKICHSHSEEFIKKEPLSDTTSPCVTDVQIILDSNVTKDTNVDKVQLKNCKWYQKNALLDKVSGGEIKKGLLHHAQNKIGPDHSYVPISSSAAEKEEEVNARLLQCVSKQKILLSQARRTQKHLQMLLAKHVVKHYGQQMKFSMKHQLPKVKIFHEPTTILDNSLPKCTEIKPDINILTAETKLWNDTKNGFARCTAAEIQRFALSATGLLSHVEEGLDSDATDSSSDDDLDEYTVRKNVSVNCSTEWKWLVDRARVGSRWTWLQAQISELEYKIQQLTDVHRQIRASKGIVILEECRLPKDILKKQVQFADHPASLNTSGTPQIPQESQDPLPEQDFEMSPSSPTLLLRNIEKQSAQLTEIINSLIAPLNLSPTSSPLSSKSCSHKCLANGISRSASENLDELSSSSSWLLNQKHSKKRRKDRTRLKSPSLTIMSTAARTRPLQSFHKRKLYRLSPTFYWTPQTLPSKETRFLNTTQMPCLQSASIWSSCEHNSKSQMLTEHVSELDSSFHSVLSLPSDVPLRFHFETLLKKTEIKGDLTENKFLGDCIISPSPVRNTSLNQWRNGYSSICKPQIESESSVQLLQGRKKRHLSETAIGERTRFEEFAFQRTEPGSQSTFTAVTNVNVLSRTQNSSSQNTARRRLRSESSYDIDNIVIPMSLVAPAKLEKLQYKEILTPSWRMVVLQPLDEYDLGEEEIENLSDEVFSLRHKKYEEKEQARWSLWEQSKWQRRNSRAYPKNVEGQDLLLKDCPYDFSGGQHCTVGSPAEPPSESQASSAHGSPSLSQETKSLWWERRTFPLKDEDTEALLCQDEKNDQVERSSPAFHGEVFCTSAPENGHHPKRQADGIEEYKTLGLGLTHVKKNR", "length": 987 }, "evidence": [ { "id": "A0A8V0YAS4", "url": "https://omabrowser.org/oma/group/A0A8V0YAS4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AUZ9-1", "protein_name": "KAT8 regulatory NSL complex subunit 1-like protein", "gene_name": "KANSL1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPALREATAKGISFSSLPSTMESDKMLYMESPRTVDEKLKGDTFSQMLGFPTPEPTLNTNFVNLKHFGSPQSSKHYQTVFLMRSNSTLNKHNENYKQKKLGEPSCNKLKNILYNGSNIQLSKICLSHSEEFIKKEPLSDTTSQCMKDVQIILDSNITKDTNVDKVQLQNCKWYQENALLDKVTDAEIKKGLLHCTQKKIVPGHSNVPVSSSAAEKEEEVHARLLHCVSKQKILLSQARRTQKHLQMLLAKHVVKHYGQQMKLSMKHQLPKMKTFHEPTTILGNSLPKCTEIKPEVNTLTAENKLWDDAKNGFARCTAAEIQRFAFSATGLLSHVEEGLDSDATDSSSDDDLDEYTLRKNVAVNCSTEWKWLVDRARVGSRWTWLQAQISDLECKIQQLTDIHRQIRASKGIVVLEECQLPKDILKKQMQFADQAASLNILGNPQVPQECQDPVPEQDFEMSPSSPTLLLRNIEKQSAQLTEIINSLIAPLNLSPTSSPLSSKSCSHKCLANGIYRSASENLDELSSSSSWLLNQKHSKKKRKDRTRLKSSSLTFMSTSARTRPLQSFHKRKLYRLSPTFYWTPQTLPSKETAFLNTTQMPCLQSASTWSSYEHNSESYLLREHVSELDSSFHSVLSLPSDVPLHFHFETLLKKTEIKGNLAENKFVDEYIISPSPVHSTLNQWRNGYSPICKPQIRSESSAQLLQGRKKRHLSETALGERTKLEESDFQHTESGSHSNFTAVSNVNVLSRIQNSSRNTARRRLRSESSYDIDNIVIPMSLVAPAKLEKLQYKEILTPSWRMVVLQPLDEYNLGKEEIEDLSDEVFSLRHKKYEEREQARWSLWEQSKWHRRNSRAYSKNVEGQDLLLKEYPNNFSSSQQCAAASPPGLPSENQDLCAYGLPSLNQSQETKSLWWERRAFPLKGEDMAALLCQDEKKDQVERSSTAFHGEIFGTSVPENGHHPKKQSDGMEEYKTFGLGLTNVKKNR", "length": 987 }, "evidence": [ { "id": "A0A8V0YAS4", "url": "https://omabrowser.org/oma/group/A0A8V0YAS4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZZY7-1", "protein_name": "KAT8 regulatory NSL complex subunit 1-like", "gene_name": "Kansl1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTPALKEATTKGICFSSLPNTMESDKMLCMESPRAVDEKLKGGDTFSQMLGFPTPEPTLNTNFVNLKHFTSPQASKHFQTVLLMSSNSTLNKYNENYNQKKVMESNCCKLKNALCNGSSVQLSKICHSHSENEIIKKELSDTTSQCMKDIQIVLDSNLTKDANVDKVHLQNCKWYQKNALLDKFTDTKIKKGLLQCTQKKIGPSHSDVPASSSAAEKEEEVNARLLHCVSKQKSLLSQARRTQKHLQMLLAKHVVKHYGQQMKFSMKHQLPTMKIFHEPTTVLSNSLLEHTEIKPEVNILASENKFWDDTNNGFSQCTAAEIQRFALSATGLLSHVEEGLDSDATDSSSDDELDEYTIRKNVAVNSSTEWKWLIDRAQVGSRWTWLQAQISELEYKIQQLTDIHRQIRASKGIVILEECQLPKDILKKQIQFSNQAVSLNTSVNSQVSQRSEEPLPEHDFEMSPSSPTLLLRNIEKQSAQLTEIINSLIAPLNLSPTSSPLSSKSCSHKCLANGISRSASENLDELSSSSSWLLNQKHSKKRRKDRTRLKSPSLAIMSTAARTRPLQSFHKRKLYRLSPTFYWTPETLPSKEAFLNTTQMPYMGSPLSWDKWEQSSKSHLSREHVSKLDPSFHPVLSLPSEIPLHLHFETLFKKTDIKGELAENKFVGDCIISPPPVQGTSLNQWRNGYSPVCKPQIRSQSSAQLLQGRKKRHLSETALAGERTRFEEFAFQRSEPGSHCNFTAVSNPNVTSRTQNSSSQNTARRRLRSESSYDIDNIVIPMSLVAPAKLEKLQYKEILTPRWRMVVLQPLDEHNLNKEEIEDLSDEVFSLRHRKYEEREQARWSLWEQSKWHRRNNRAYSKNVEGQDLVLKEHSRELGSVQQGAAESPFELPAESHSLCTQDSLSLNDGQEVKPLRWERRAFPLKDEDTAALLCQDERKDLTEGASTAFRDEAFCSTTPENSHPPSVQLDGMEEYKIFGIGVTSVKRNR", "length": 990 }, "evidence": [ { "id": "A0A8V0YAS4", "url": "https://omabrowser.org/oma/group/A0A8V0YAS4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5DTI6-1", "protein_name": "KAT8 regulatory NSL complex subunit 1-like protein", "gene_name": "Kansl1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPALKEATTKGICFSSLPNTMESDKMLCMESPRTVDEKLKGGDTFSQMLGFPTPEPTLNTNFVNLKHFASPQASKHFQTVLLMSSNSTLNKYNENYNQKKVMESNCSKLKNVLCNGSSIQLSKICPSHSENEFIKKELSDTTSQCMKDIQIVLDSNLTKDANVDRLHLQNCKWYQKNALLDKFTDTKIKKGLLQCTQKKIGPSHSDVPTSSSAAEKEQEVNARLLHCVSKQKILLSQARRTQKHLQMLLAKHVVKHYGQQMKFSMKHQLPTMKIFHEPTTVLSNSLLEHTEIKPEVNILASENKFWDDTNNGFSQCTAAEIQRFALSATGLLSHVEEGLDSDATDSSSDDELDEYTIRKNVAVNSSTEWKWLVDRAQVGSRWTWLQAQISELEYKIQQLTDIHRQIRASKGIVILEECQLPKDILKKQIQFSNQAVSLNTSVNSQVPQRSEEPLPEHDFEMSPSSPTLLLRNIEKQSAQLTEIINSLIAPLNLSPTSSPLSSKSCSHKCLANGISRSASENLDELSSSSSWLLNQKHSKKRRKDRTRLKSPSLAIMSTAARTRPLQSFHKRKLYRLSPTFYWTPETLPSKEAFLSSTQTPYTGSPFSWDNWEQSSRSHLLREQVSKLDSSFHPVLSLPSEIPLHLHFETLFKKTDMKGELAENQFVGDCLISPPPVQGTSSLNQWRNGYSPICKPQIRSQPSVQLLQGRKKRHLSETALAGERTRFEEFAFQRSEPGSHCNFTAVSNANVTSRTQNPSSQNTSRRRLRSESSYDIDNIVIPMSLVAPAKLEKLQYKEILTPRWRKVVLQPLDEHNLNKEEIEDLSDDVFSLRHRKYEEREQARWSLWEQSKWHRRNNRAYSKNVEGQDLVLKEHSSELGSAQQGTAESPFELPAESHSLCAQDSLSLNDGQEDKSLRWERRAFPLKDEDTAALLCQDERKDQTGGTSTAFHDEVFCSTTPESGHPPKMQLDGMEEYKSFGIGVTNVKRNR", "length": 991 }, "evidence": [ { "id": "A0A8V0YAS4", "url": "https://omabrowser.org/oma/group/A0A8V0YAS4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "H4 histone acetyltransferase complex", "id": "GO:1902562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902562", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4" } ], "pmid": "" }, { "name": "NSL complex", "id": "GO:0044545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044545", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone acetyltransferase binding", "id": "GO:0035035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 947, "end_pos": 949, "annotation": "n_glycosylation_sequon" }, { "start_pos": 996, "end_pos": 998, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAS4" }, { "id": "PS52052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PEHE", "eco_id": "ECO_0000259", "start_pos": 799, "end_pos": 924, "start_aa": "Glu", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 947, "end_pos": 949 }, { "start_pos": 996, "end_pos": 998 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9P2-1", "uniprot_ac": "A0A8V0Y9P2", "uniprot_id": "A0A8V0Y9P2_CHICK", "mass": { "chemical_mass": 57555.0, "monoisotopic_mass": 57555.0 }, "refseq": { "ac": "NP_001383197", "name": "beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383197" }, "gene_names": [ { "name": "MGAT3", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ] }, { "name": "MGAT3", "type": "synonym", "evidence": [ { "id": "NP_001383197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383197" } ] } ], "protein_names": [ { "name": "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2/entry#names_and_taxonomy" } ] }, { "name": "beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001383197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383197" } ] }, { "name": "mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001383197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383197" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888509.141249.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Oct 5, 2021 this sequence version replaced XP_015140671.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383197" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MGAT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2", "locus": { "chromosome": "1", "start_pos": 50663867, "end_pos": 50697396, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012517", "url": "https://www.ensembl.org/id/ENSGALG00010012517" } ] } } ], "crossref": [ { "id": "418013", "url": "https://www.ncbi.nlm.nih.gov/gene/418013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QPEIIWR", "url": "https://omabrowser.org/oma/group/QPEIIWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9P2", "url": "https://www.orthodb.org/?gene=A0A8V0Y9P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12224:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12224:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04724", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04724", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-975574", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975574", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001383197", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMRRHKLFLTLCMAGLCLISFLHFLKALSYVTFPRDLASLSPNLVSSFFWNNAPVTPQVSPEPGGAEFLRTPLYSHSPLLQPLPPSRASEELHKVEFVLPEDTTEYFVRTKAGGVCFKPGTKVLEKPPAGGRPEERVDGVASGRPARKPLSAGGTKRRKWVECVCLPGWHGPSCGVPTVVQYSNLPTKDRLVPREIPRRVINAININHEFDLLDVRFHELGDVVDVFVVCESNFTAYGEPRPLKFREMLLNGSYEYIRHKVLYVFLDHFPAGGRQDGWIADDYLRTFLTRDGVSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLEVVSGCTMGMLQAVYATDGIRLRRREYYTMPGFRQYENSTGHILVQWSLGSPLHFAGWHCSWCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRELIRTGGWFDGTTQEYPPADPKEHMYAPKYLLKNYQQFHYLLENPYRKAEGAG", "length": 502, "header": "tr|A0A8V0Y9P2-1|A0A8V0Y9P2_CHICK Isoform 1 of Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MGAT3 PE=4 SV=1 CANONICAL=A0A8V0Y9P2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2/entry#A0A8V0Y9P2-1", "sequence": { "sequence": "MKMRRHKLFLTLCMAGLCLISFLHFLKALSYVTFPRDLASLSPNLVSSFFWNNAPVTPQVSPEPGGAEFLRTPLYSHSPLLQPLPPSRASEELHKVEFVLPEDTTEYFVRTKAGGVCFKPGTKVLEKPPAGGRPEERVDGVASGRPARKPLSAGGTKRRKWVECVCLPGWHGPSCGVPTVVQYSNLPTKDRLVPREIPRRVINAININHEFDLLDVRFHELGDVVDVFVVCESNFTAYGEPRPLKFREMLLNGSYEYIRHKVLYVFLDHFPAGGRQDGWIADDYLRTFLTRDGVSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLEVVSGCTMGMLQAVYATDGIRLRRREYYTMPGFRQYENSTGHILVQWSLGSPLHFAGWHCSWCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRELIRTGGWFDGTTQEYPPADPKEHMYAPKYLLKNYQQFHYLLENPYRKAEGAG", "length": 502, "header": "tr|A0A8V0Y9P2-1|A0A8V0Y9P2_CHICK Isoform 1 of Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase OS=Gallus gallus OX=9031 GN=MGAT3 PE=4 SV=1 CANONICAL=A0A8V0Y9P2-1" }, "locus": { "chromosome": "1", "start_pos": 50674095, "end_pos": 50672590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030013.1", "url": "https://www.ensembl.org/id/ENSGALT00010030013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017446.1", "url": "https://www.ensembl.org/id/ENSGALP00010017446.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-975574", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975574", "resource": "Reactome", "description": "Reactions specific to the hybrid N-glycan synthesis pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AW36-1", "protein_name": "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase", "gene_name": "MGAT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQASPEPGSPDLLRTPLYSHSPLLQPLSPSKATEELHRMDFAMPEDTAEYFVRTKAGGVCFKPGTKTLEKPPSGRPEEKAEVGDGSSARGPARHLLSTRERPGARSARRKWVECVCLPGWHGPSCGVPTVVQYSNLPTKERLVPREVPRRIINAININHEFDLLDVRFHELGDVVDAFVVCESNFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPLGGRQDGWIADDYLRTFLTQDGVSRLRNLRPDDVFIINDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLEVVSGCTVDMLQTVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCSWCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRSLIRTGGWFDGTQQEYPPADPSEHMYAPKYLLKNYDQFRYLLDNPYQEPKSTADGGRRNKGPQGRPPARDKLDVVEG", "length": 533 }, "evidence": [ { "id": "A0A8V0Y9P2", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q02527-1", "protein_name": "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase", "gene_name": "Mgat3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLISSFFWNNAPVTPQASPEPGDPDLLRTPLYSHSPLLQPLSPSKATEELHRVDFVLPEDTTEYFVRTKAGGVCFKPGTRMLEKPSPGRTEEKTKVAEGSSVRGPARRPMRHVLSARERLGGRGTRRKWVECVCLPGWHGPSCGVPTVVQYSNLPTKERLVPREVPRRVINAININHEFDLLDVRFHELGDVVDAFVVCESNFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDGVSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLEVVSGCTIDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCSWCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRSLIRTGGWFDGTQQEYPPADPSEHMYAPKYLLKNYDQFRYLLENPYREPKSTVEGGRRNQGSDGRSSAVRGKLDTTEG", "length": 538 }, "evidence": [ { "id": "A0A8V0Y9P2", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q09327-1", "protein_name": "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase", "gene_name": "MGAT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQASPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKPGTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGPSCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCESNFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDGVSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLEVVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCSWCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEHMYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV", "length": 533 }, "evidence": [ { "id": "A0A8V0Y9P2", "url": "https://omabrowser.org/oma/group/A0A8V0Y9P2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "N-acetylglucosamine metabolic process", "id": "GO:0006044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity", "id": "GO:0003830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ], "pmid": "" }, { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9P2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 390, "end_pos": 392 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB89-1", "uniprot_ac": "A0A8V0YB89", "uniprot_id": "A0A8V0YB89_CHICK", "mass": { "chemical_mass": 89696.0, "monoisotopic_mass": 89696.0 }, "refseq": {}, "gene_names": [ { "name": "EFHC2", "type": "recommended", "evidence": [ { "id": "A0A8V0YB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ] } ], "protein_names": [ { "name": "EF-hand domain-containing family member C2", "type": "recommended", "evidence": [ { "id": "A0A8V0YB89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YDH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH1#function" }, { "database": "UniProtKB", "id": "ARBA00035003", "url": "https://www.uniprot.org/uniprotkb/ARBA00035003#function" }, { "database": "UniProtKB", "id": "A0A8V0YI59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI59#function" }, { "database": "UniProtKB", "id": "A0A8V0YI63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI63#function" }, { "database": "UniProtKB", "id": "A0A8V0Y9Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q3#function" }, { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFHC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89", "locus": { "chromosome": "1", "start_pos": 111193344, "end_pos": 111131909, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011468", "url": "https://www.ensembl.org/id/ENSGALG00010011468" } ] } } ], "crossref": [ { "id": "A0A8V0YB89", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB89", "database": "AlphaFoldDB", "categories": [] }, { "id": "418559", "url": "https://www.ncbi.nlm.nih.gov/gene/418559", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040193", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040193", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418559", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418559", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RFSCKQP", "url": "https://omabrowser.org/oma/group/RFSCKQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9Q3", "url": "https://www.orthodb.org/?gene=A0A8V0Y9Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB89", "url": "https://www.orthodb.org/?gene=A0A8V0YB89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDH1", "url": "https://www.orthodb.org/?gene=A0A8V0YDH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI59", "url": "https://www.orthodb.org/?gene=A0A8V0YI59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI63", "url": "https://www.orthodb.org/?gene=A0A8V0YI63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12086:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12086:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y9Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPLLPGFSLGRNLKSTASCCECTRALKSKMLRCSAPKGLQWVGKEKFHKSQHWGYCNNVAMLLAEDKPGIGGEPLPGQKLTPKSSVFPAELGCGAPAWLAFDKQVLSFDAYFEEEVPDKNQEPYRIRHCKIYFYLEDDTIQVLEPQVKNSGIIQGTIVRRHRIPLPSPNEDQFYTIDHFNINAEVIFYARRYKIIDCDQFTKHFLRKMGFKLNPPGNRPDDPYTKERQKILDSVNPLRPYERIDTLKQFLEHDGHVLRFYCVWDDPESLFHDPRELVLHYYLSDDTIDIKEVIPVNSGRDVVPLFLRRDKLPKYAPTGLYQPGTITSRTVLNVFGNLVGNRGRYILDNRKTGAVHQEFYRDSDLKIGAVINVWGRQIMLCDCDEFTKDYYRTKYGIEDFTPVPYKAPPPPKAEKPIPPYTGFGSEEDSLCSCMSLLPKPPQKDFKKFMEKDRCGLESNTLRFLAKLVTDSPIDKDRKFIICYFLSDDTISVFEHSQRNTGIIGGKFLEKGRIKKPGQELFKSEPSEYFKAQDLFIGARVCFHGHNFLLVDADEYTINYMEKHANEFAVADTGFIFKKLKDIAEPRSREIRQVFAAADPQHTKVIEYDPFRNLIVSITDGAFSEHEIMTLGRHYGEKEEYEIDHHFLLAKAQEQLKKNSFENFEQLSTILVYNDREKCGALPYETCRTICKSFKLPLSDDLLQTILTMFEDDHKQVNYKKFVDAVNWREHQIPSFHTIKLPPKNEDDWNGQPPFLPVKRIKYLPLLDDLFGKEE", "length": 775, "header": "tr|A0A8V0YB89-1|A0A8V0YB89_CHICK Isoform 1 of EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=4 SV=1 CANONICAL=A0A8V0YB89-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89/entry#A0A8V0Y9Q3-1", "sequence": { "sequence": "MKNEQVLSFDAYFEEEVPDKNQEPYRIRHCKIYFYLEDDTIQVLEPQVKNSGIIQGTIVRRHRIPLPSPNEDQFYTIDHFNINAEVIFYARRYKIIDCDQFTKHFLRKMGFKLNPPGNRPDDPYTKERQKILDSVNPLRPYERIDTLKQFLEHDGHVLRFYCVWDDPESLFHDPRELVLHYYLSDDTIDIKEVIPVNSGRDVVPLFLRRDKLPKYAPTGLYQPGTITSRTVLNVFGNLVGNRGRYILDNRKTGAVHQEFYRDSDLKIGAVINVWGRQIMLCDCDEFTKDYYRTKYGIEDFTPVPYKAPPPPKAEKPIPPYTGFGSEEDSLCSCMSLLPKPPQKDFKKFMEKDRCGLESNTLRFLAKLVTDSPIDKDRKFIICYFLSDDTISVFEHSQRNTGIIGGKFLEKGRIKKPGQELFKSEPSEYFKAQDLFIGARVCFHGHNFLLVDADEYTINYMEKHANEFAVADTGFIFKKLKDIAEPRSREIRQVFAAADPQHTKVIEYDPFRNLIVSITDGAFSEHEIMTLGRHYGEKEEYEIDHHFLLAKAQEQLKKNSFENFEQLSTILVYNDREKCGALPYETCRTICKSFKLPLSDDLLQTILTMFEDDHKQVNYKKFVDAVNWREHQIPSFHTIKLPPKNEDDWNGQPPFLPVKRIKYLPLLDDLFGKEE", "length": 674, "header": "tr|A0A8V0Y9Q3-1|A0A8V0YB89_CHICK Computationally mapped isoform of EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=4 SV=1 CANONICAL=A0A8V0YB89-1" }, "locus": { "chromosome": "1", "start_pos": 111192912, "end_pos": 111143530, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027455.1", "url": "https://www.ensembl.org/id/ENSGALT00010027455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015709.1", "url": "https://www.ensembl.org/id/ENSGALP00010015709.1" } ] } }, { "isoform_ac": "A0A8V0YB89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89/entry#A0A8V0YB89-1", "sequence": { "sequence": "MALPLLPGFSLGRNLKSTASCCECTRALKSKMLRCSAPKGLQWVGKEKFHKSQHWGYCNNVAMLLAEDKPGIGGEPLPGQKLTPKSSVFPAELGCGAPAWLAFDKQVLSFDAYFEEEVPDKNQEPYRIRHCKIYFYLEDDTIQVLEPQVKNSGIIQGTIVRRHRIPLPSPNEDQFYTIDHFNINAEVIFYARRYKIIDCDQFTKHFLRKMGFKLNPPGNRPDDPYTKERQKILDSVNPLRPYERIDTLKQFLEHDGHVLRFYCVWDDPESLFHDPRELVLHYYLSDDTIDIKEVIPVNSGRDVVPLFLRRDKLPKYAPTGLYQPGTITSRTVLNVFGNLVGNRGRYILDNRKTGAVHQEFYRDSDLKIGAVINVWGRQIMLCDCDEFTKDYYRTKYGIEDFTPVPYKAPPPPKAEKPIPPYTGFGSEEDSLCSCMSLLPKPPQKDFKKFMEKDRCGLESNTLRFLAKLVTDSPIDKDRKFIICYFLSDDTISVFEHSQRNTGIIGGKFLEKGRIKKPGQELFKSEPSEYFKAQDLFIGARVCFHGHNFLLVDADEYTINYMEKHANEFAVADTGFIFKKLKDIAEPRSREIRQVFAAADPQHTKVIEYDPFRNLIVSITDGAFSEHEIMTLGRHYGEKEEYEIDHHFLLAKAQEQLKKNSFENFEQLSTILVYNDREKCGALPYETCRTICKSFKLPLSDDLLQTILTMFEDDHKQVNYKKFVDAVNWREHQIPSFHTIKLPPKNEDDWNGQPPFLPVKRIKYLPLLDDLFGKEE", "length": 775, "header": "tr|A0A8V0YB89-1|A0A8V0YB89_CHICK Isoform 1 of EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=4 SV=1 CANONICAL=A0A8V0YB89-1" }, "locus": { "chromosome": "1", "start_pos": 111192912, "end_pos": 111133717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027463.1", "url": "https://www.ensembl.org/id/ENSGALT00010027463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015717.1", "url": "https://www.ensembl.org/id/ENSGALP00010015717.1" } ] } }, { "isoform_ac": "A0A8V0YDH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89/entry#A0A8V0YDH1-1", "sequence": { "sequence": "SVLPLMGGRVCGVGKEKFHKSQHWGYCNNVAMLLAEDKPGIGGEPLPGQKLTPKSSVFPAELGCGAPAWLAFDKQVLSFDAYFEEEVPDKNQEPYRIRHCKIYFYLEDDTIQVLEPQVKNSGIIQGTIVRRHRIPLPSPNEDQFYTIDHFNINAEVIFYARRYKIIDCDQFTKHFLRKMGFKLNPPGNRPDDPYTKERQKILDSVNPLRPYERIDTLKQFLEHDGHVLRFYCVWDDPESLFHDPRELVLHYYLSDDTIDIKEVIPVNSGRDVVPLFLRRDKLPKYAPTGLYQPGTITSRTVLNVFGNLVGNRGRYILDNRGILFHFDYCSVREVEQEQINLAVFIIEDFTPVPYKAPPPPKAEKPIPPYTGFGSEEDSLCSCMSLLPKPPQKDFKKFMEKDRCGLESNTLRFLAKLVTDSPIDKDRKFIICYFLSDDTISVFEHSQRNTGIIGGKFLEKGRIKKPGQELFKSEPSEYFKAQDLFIGARVCFHGHNFLLVDADEYTINYMEKHANEFAVADTGFIFKKLKDIAEPRSREIRQVFAAADPQHTKVIEYDPFRNLIVSITDGAFSEHEIMTLGRHYGEKEEYEIDHHFLLAKAQEQLKKNSFENFEQLSTILVYNDREKCGALPYETCRTICKSFKLPLSDDLLQTILTMFEDDHKQVNYKKFVDAVNWREHQIPSFHTIKLPPKNEDDWNGQPPFLPVKRIKYLPLLDDLFGKEE", "length": 723, "header": "tr|A0A8V0YDH1-1|A0A8V0YB89_CHICK Computationally mapped isoform of EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=4 SV=1 CANONICAL=A0A8V0YB89-1" }, "locus": { "chromosome": "1", "start_pos": 111192912, "end_pos": 111141080, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027459.1", "url": "https://www.ensembl.org/id/ENSGALT00010027459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015713.1", "url": "https://www.ensembl.org/id/ENSGALP00010015713.1" } ] } }, { "isoform_ac": "A0A8V0YI59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89/entry#A0A8V0YI59-1", "sequence": { "sequence": "MALPLLPGFSLGRNVGKEKFHKSQHWGYCNNVAMLLAEDKPGIGGEPLPGQKLTPKSSVFPAELGCGAPAWLAFDKQVLSFDAYFEEEVPDKNQEPYRIRHCKIYFYLEDDTIQVLEPQVKNSGIIQGTIVRRHRIPLPSPNEDQFYTIDHFNINAEVIFYARRYKIIDCDQFTKHFLRKMGFKLNPPGNRPDDPYTKERQKILDSVNPLRPYERIDTLKQFLEHDGHVLRFYCVWDDPESLFHDPRELVLHYYLSDDTIDIKEVIPVNSGRDVVPLFLRRDKLPKYAPTGLYQPGTITSRTVLNVFGNLVGNRGRYILDNRKTGAVHQEFYRDSDLKIGAVINVWGRQIMLCDCDEFTKDYYRTKYGIEDFTPVPYKAPPPPKAEKPIPPYTGFGSEEDSLCSCMSLLPKPPQKDFKKFMEKDRCGLESNTLRFLAKLVTDSPIDKDRKFIICYFLSDDTISVFEHSQRNTGIIGGKFLEKGRIKKPGQELFKSEPSEYFKAQDLFIGARVCFHGHNFLLVDADEYTINYMEKHANEFAVADTGFIFKKLKDIAEPRSREIRQVFAAADPQHTKVIEYDPFRNLIVSITDGAFSEHEIMTLGRHYGEKEEYEIDHHFLLAKAQEQLKKNSFENFEQLSTILVYNDREKCGALPYETCRTICKSFKLPLSDDLLQTILTMFEDDHKQVNYKKFVDAVNWREHQIPSFHTIKLPPKNEDDWNGQPPFLPVKRIKYLPLLDDLFGKEE", "length": 746, "header": "tr|A0A8V0YI59-1|A0A8V0YB89_CHICK Computationally mapped isoform of EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=4 SV=1 CANONICAL=A0A8V0YB89-1" }, "locus": { "chromosome": "1", "start_pos": 111192912, "end_pos": 111133717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027462.1", "url": "https://www.ensembl.org/id/ENSGALT00010027462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015716.1", "url": "https://www.ensembl.org/id/ENSGALP00010015716.1" } ] } }, { "isoform_ac": "A0A8V0YI63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89/entry#A0A8V0YI63-1", "sequence": { "sequence": "MLVQSFQKDILAHKRSKTPWMPFLKILSNESCESGKVGKEKFHKSQHWGYCNNVAMLLAEDKPGIGGEPLPGQKLTPKSSVFPAELGCGAPAWLAFDKQVLSFDAYFEEEVPDKNQEPYRIRHCKIYFYLEDDTIQVLEPQVKNSGIIQGTIVRRHRIPLPSPNEDQFYTIDHFNINAEVIFYARRYKIIDCDQFTKHFLRKMGFKLNPPGNRPDDPYTKERQKILDSVNPLRPYERIDTLKQFLEHDGHVLRFYCVWDDPESLFHDPRELVLHYYLSDDTIDIKEVIPVNSGRDVVPLFLRRDKLPKYAPTGLYQPGTITSRTVLNVFGNLVGNRGRYILDNRKTGAVHQEFYRDSDLKIGAVINVWGRQIMLCDCDEFTKDYYRTKYGIEDFTPVPYKAPPPPKAEKPIPPYTGFGSEEDSLCSCMSLLPKPPQKDFKKFMEKDRCGLESNTLRFLAKLVTDSPIDKDRKFIICYFLSDDTISVFEHSQRNTGIIGGKFLEKGRIKKPGQELFKSEPSEYFKAQDLFIGARVCFHGHNFLLVDADEYTINYMEKHANEFAVADTGFIFKKLKDIAEPRSREIRQVFAAADPQHTKVIEYDPFRNLIVSITDGAFSEHEIMTLGRHYGEKEEYEIDHHFLLAKAQEQLKKNSFENFEQLSTILVYNDREKCGALPYETCRTICKSFKLPLSDDLLQTILTMFEDDHKQVNYKKFVDAVNWREHQIPSFHTIKLPPKNEDDWNGQPPFLPVKRIKYLPLLDDLFGKEE", "length": 768, "header": "tr|A0A8V0YI63-1|A0A8V0YB89_CHICK Computationally mapped isoform of EF-hand domain-containing family member C2 OS=Gallus gallus OX=9031 GN=EFHC2 PE=4 SV=1 CANONICAL=A0A8V0YB89-1" }, "locus": { "chromosome": "1", "start_pos": 111192912, "end_pos": 111132108, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027467.1", "url": "https://www.ensembl.org/id/ENSGALT00010027467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015721.1", "url": "https://www.ensembl.org/id/ENSGALP00010015721.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418559", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418559", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N1R0-1", "protein_name": "EF-hand domain-containing family member C2", "gene_name": "EFHC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKEKFHKSQHWGFCNNVRMLVGEDKPGIGGELLFGQKIKPKYSVFPKGMGTDSPSWVAFDKQVLSFDAYLEDEVPDKSQENYRIRRYKIYFYLEDDTVEVNEPVLQNSGLPQGIFIRRHRISLPPPNEDQFYTVHHFNVNTDIVFYGRTFKVYDCDAFTKNFLTKIGVKLNPPGQCPEDPYMKTRREKLDCMEPICPYESFDTLKQFLEYDRKVLRFFCVWDDSGSVFGDRRELILHYFLSDDTIEIKEVLPHNSGRDAMSLFLQRRKLPKYGPPGVYQPGQLTDQTVLNVYGGYSETRVYGFLLDKYQLGKLDQEFYKDTDLSIGTTINVWGRKVLLCDCDDFTKTYYRTKYGIENFTSIPCKAPSPPKIERKFPPYTGFGSEEDSLRSCIGLMPTPHQRNFKKFIEFDSYGNISNTLRFFAKLITHKCADVERMFVISYFLSDDTISVFEPIERNSGYTGGMFLKRVRVKKPGQEVFKSEFSEYIKAEELYVGAKVNVNGYLFFLVNADEYTLNYMERNSDKFPLSSIELVIQKLKEEECKSRELKQVFTAADCMHTKMVDFNTFREIMMNLTVGKLTDQEVITIARRYRVPEDPCPHRNVLVAQAHEQLKKNAFENFERLIAMCVYEDREKKKVLPSKDIKRLCKSSRLPLNEDLLGSLLSGFEDSEKQINYESFFCALNWRVNPVPVLEVASYIKERCEDEWLGMPSPIPVKYIYYLNLLKDVFGVDE", "length": 733 }, "evidence": [ { "id": "A0A8V0YB89", "url": "https://omabrowser.org/oma/group/A0A8V0YB89/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZKF6-1", "protein_name": "EF-hand domain-containing family member C2", "gene_name": "Efhc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALPLLPGNSFNRNIGKEKFHRSQHWGFCNNVRMLVSEDKPGIGGDLLPGQKIKPKHSVFPKGDGTDAPSWVAFDKQVLSFDAYLEDEVPDKRQENFRIRYYKIYFYLEDDTIQVNEPEVINSGLPQGTSIRRHRIPFPPPYDDQFYTVYDFNINISVVFYGRTFKIYDCDPFTKNFLRKIGIKLNPPGQRPFDPYMKMRRETLEFVDPFRPYQSFDTLKRFLQYDGKVLRFFCLWDDSASLFGDRREFVLHYFLCDDTIEIREILPSNSGRDAMSSFLRRSKLPKFGPPGIYQPGQITDRAVLNVYGGLSEWRADGYLLDKYQLGKIEQDFYTDQDLSIGATINVWGRKVLLCDCDEFTKTYYKTKYGVDNFTPISCKPPPLPKIKRKYPPYTGFGSEEDSFRSCVSLKPTPHRKNFRKFMELDSFGNVSNILRYFAKLITHKCADVDRMFVIAFYLSDDTISVFEPIERNSGNAGGMFLKRSRVKKPGQEVFKSEFSEYVKAEELYIGATVNINGYLFLLLNADEYTLNYMESNTDRFPYSNFELAIQKLKHEKSKSREITQVFAAADYNHTKVVPYNAFRDILMSITMGNLIDQELITIARHYRVPEVMDPDLAYLIAQAHEKFKKNMFENFDMFIYNCVYEDRERKGVLPTTDIKRMCKSSRLPLSDDFLDCLLSRFEDKDQQINYEIFFSLLNWRMNPTPDLQAPPYLKEKCEDVWVGMPSPIPVRYVRYLDFLMDVYGLEENMP", "length": 750 }, "evidence": [ { "id": "A0A8V0YB89", "url": "https://omabrowser.org/oma/group/A0A8V0YB89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7GSU4-1", "protein_name": "EF-hand domain-containing family member C2", "gene_name": "EFHC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALPLLPGNSFNRNIGKEKFHKSQHWGFCNNVRMLVSEDKPGIGGELLLGQKMKPKYSVFPKEMGTGLPSWVAFDKQVLSFDAYLEDEVPDKSQENYRIRCYKIYFYLEDDTIQVNEPALKNSGLPKGIFIRRHRISLPPPDEDQFYTVYHFNINVDIVLYGRTFKIYDCDTFTKNFLKKIGVKLNPPGQCPEDPYMKTRREKLDCVEPLRPYESFDTLKQFLEYDRKVLRFFCLWDDSGSLFGDRRELILHYFLSDDTIEIKEVMPHNSGRDAMSLFLQRRKLPKYGPPGVYQPGQIADRTVLNVYGGLSRRRVYSYLLDKYKLGNLDQEFYKDSDLSIGTTINVWGRKVLLCDCDEFTKTYYKTKYGIENFTSISCKAPPPPKIERKFPPYTGFGSEEDSLRSCIGLVPTPHRRNFKKFMEKDSYGNISNTLRFFAKLITHKCADVERMFVISYFLSDDTISVFEPIERNSGYTGGMFLKRTRVKKPGQEVFKSEFSEYVKAEELYVGAKVDVNGYLFLLLNADEYTLNYMEKNSDKFPRSNIKLALQKVKEEESKSRELKQVFTAADCKHTKMVDYNTFREIMMNLTVGKLTDQELITIARHYRVPEEPCPDTCIVMAQAHEQLKKHAFENFERLIAACVYQDREKKKVLPSKDIKRLCKSSRLPFNDDLLGALLSKFEDSEKQINYESFFCALNWRANPMPELEAVSYLKERCEDEWLGMPSPIPVKCISYLNLLKDVFGLEEE", "length": 748 }, "evidence": [ { "id": "A0A8V0YB89", "url": "https://omabrowser.org/oma/group/A0A8V0YB89/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q32TF8-1", "protein_name": "EF-hand domain-containing family member C2", "gene_name": "efhc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALPMLPGNSVNRNLGKDKFHKSQHFDYSNGVAMMVGTEKPGIGGDLLLGQSARAKYSRFPKGEGSGAPAWLAFDKQVLCFDAYFNEAVPQRREEKYRVRKCKIYFYLEDDTIQVVEPEFKNSGIPQGTLIRRHRIPLPAPKDDCFYNVHHFNINQEVLFYSRNFMITDCDPFTRNFLVKMGVRLNPPASTPADPYTTLRQELEENMKPLRPYERLDTLKQFLEHDRQVLRFYCYWDDSESMFGDPRELILHYFLADDTMEMYEVVPPNSGRDTVPKFLHRGKLPKHAPIPKRQPGEITDRTVLNVFGPVGQGGPYILDSLKTGALEEEFYKDSDLTIGAVINVWGRRVLICDCDYFTKEYYRSKYGIEDFPSISYKASPPPKPAKQVPPYTGFGSEEDSLCSCQGLLPKPPQKDFKKLMEKDRRGLVSNVLRFVGKMLTDSPVDKERVFIICFYLTDDTIAVFEPPQRNSGVIGGKFLERGRVKKPGQELFKSEMSEYFTAQDLYVGAHLLLNSQPFQLVDADDFTFSYMEQHADEFPKANIGTIISKVKSISEEQQKTVKQFFTMSDPSSTGSLPYESFRTLLADLDVELSEHEIMTLGRVYSVRQQPEVNVGLMLAVAQDHLKKKNFEKFSEMIQAFTHEDRDRCGQLSSKEARIICKAFRLPLSDDLLRALLEKFAGESEKIDYHAFLSGINWRENPVPAVLPEDTVKFDADWRGEAPEPAVKTINYSLLLEDVFGSATNINDS", "length": 748 }, "evidence": [ { "id": "A0A8V0YB89", "url": "https://omabrowser.org/oma/group/A0A8V0YB89/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5JST6-1", "protein_name": "EF-hand domain-containing family member C2", "gene_name": "EFHC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALPLLPGNSFNRNVGKEKFHKSQHWGFCNNVMMLVSDEKPGIGGEPLLGQKIKPKCSIYPKGDGSDVPSWVAFDKQVLSFDAYLEEEVLDKSQTNYRIRYYKIYFYPEDDTIQVNEPEVKNSGLLQGTSIRRHRITLPPPDEDQFYTVYHFNVGTEVVFYGRTFKIYDCDAFTRNFLRKIGVKVNPPVQCPEDPYMKIRREVVEHVEPLRPYESLDTLKQFLQYHGKILCFFCLWDDSVSMFGDRRELILHYFLCDDTIEIKELLPHSSGRDALKMFLRRSKLPKNCPPRVYQPGQITDRAVLNSYGDFIKNQADGYLFDRYKLGKVDQEFYKDSDLSLGVTINVWGRKVLLYDCDEFTKSYYKSKYGIENFTSVSCKPPSPPPKIERKFPPYNGFGSEEDSLRNCIDLKPTPHRRNFKKFMEKDSYGSKSNILRFFAKLVTDKCVDLDRMFVISYYLGDDTISVFEPIERNSGIAGGMFLKRSRVKKPGQEVFKSELSEYIKAEELYIGVTVNVNGYLFRLLNADEYTLNYMEQNTDKYPFSNLKLALQKLKQEEGKSRELKQVFKAADSKHTNMVDYNTFRDILMSLTVGNLAEQEFVTIARHYRVPEGTCSDMDFLIALAHEKFKKNMFENFDTFIYSCVYEDREKKNVLPTKDIKRLCKSSRLPLSDDLLESLLSRFEDSEKQIDYKSFFSALNWRKNPVPELQPASYLKERCEDVWLGMPSPIPAKYIDYWTFLKDAFGLEEE", "length": 749 }, "evidence": [ { "id": "A0A8V0YB89", "url": "https://omabrowser.org/oma/group/A0A8V0YB89/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D485-1", "protein_name": "EF-hand domain-containing family member C2", "gene_name": "Efhc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALPFLPGNSFNRNIGKERFHKSQHWGFCNNVRMLVSENKPGVGGDLLYGQKIKPKHSVFPKGDGTDAPSWVAFDKQVLSFDAYLEDEISDKRQEIFRIRYYKIYFYLEDDTIQVNEPEVINSGLPQGTSIRRQRIPYPPPNDDQFYTVYDFNINISVVFYGRTFKIYDCDPFTKNFLKKIGIKLNPPGQCPLDPYMKMRRETLEFVDPFRPYQSFDTLKRFIQYDGKVLRFFCLWDDSTSLFGDRREFVLHYFLCDGTVEIREVLPSNSGRDAMSSFLRRGKLPKYGPPGIYQPGQITDRAVLNVYGGLSEWRADGYLLDKYQLGKVEQDFYTDQDLSIGATINVWGRKVLLCDCDEFTKTYYRTKYGVDNFTPISCKPPHLPKIERKYPPYTGFGSEEDSFRSCVGLKPTPHRKNFKKFMELDSFGNISNILRYFGKLITHKCADVDRIFVIAFYLSDDTISVFEPIENNSGNAGGMFLKRSRVKKPGQEVFKSEFSEYIKAEELYIGATVNINGYLFILLNADEYTLNYMENNTDKFPYSNFELAIQKLKQEKSKSREITQVFAAADYNHTKVVPYNTFRDILMSITMGKLIDQELITIARHYRVPEIMDPDLAYLIARAHEKFKKNIFENFDMFIYNCVYEDREKKGVLPTKDIRRMCKSSRLPLDDDFLDCLLSRFEDKDHQINYEIFFSVLNWRMNPTPDLQAPPYLKEKCEDVWVGMPSPIPVKYVRYLDFLIDVYGLEDNML", "length": 750 }, "evidence": [ { "id": "A0A8V0YB89", "url": "https://omabrowser.org/oma/group/A0A8V0YB89/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VXP5-1", "protein_name": "EF-hand domain containing 1.1", "gene_name": "Efhc1.1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRIPGMPLLPGTLFRDVSKGHYPKPQSLANVQGLSMLSDRQQPAPVESGSVTVDISCPPVGASSIYPPRSGPRMPPWLAYDKKVLCFHAYFKQTLQEVYHAPYLVRKVKIYYYLEDGTLEIYEPRVDNSGIVQGCVVHRQRVQKAPPCDNEFMSLIDLNVDQTVQIFDRQYHITDCDPFTRTFLNKRGITVPDPVKSPCDPTEEQRKRENQPRSGNLIPKNHPFAQFLKYDRQILKFQAYWDDRTEFGDVRKLELCYYLSDDTIEIKEQHIRNSGRDGPTVFLKRGRLAREFEGLQLPGQMTPMTLLNVLGTNMRNVRYCVDPLNTGNKEIHYYREKDLQIGSVINVYGRAVVITELDPFTQNYYRQRYGIQDFTPLPIPARSDDCADHRSERQLPPYNGWGSYEDSVGNCISVEPKPPKSDFKKFIKYDRYVLRFGAKMLSTIKANCERIFVISYYLCDDTLQIQEIAVRNSGFLGGEFMKRTRLELPGQERFSCKQPQYYMPWNFFVGSTMSLKDFIFHIVSADEYTLMYMEHHPEIFPHANVGVIMEKVKSALQNRMAEFVGSCVPDCTDLEKKRDVFVSFESFKGALISIMGNQISDHEIISLCRHFSAEKSQPNACDRSTVRAAAHLELKRTLWNARDDLMEHFHHINPTNQPFLPEVKVRSALRGCRLPFSLELIDNILSILNRNECDDIEVCDLMNFIDVSCGKGCDMLPVNHAFELCPKIPFLNKGRVVNFTCFLRELNLPLNLPAGGEKNNDAIAEGGRIMPPSAMPDTDAHKANEDDAQHMA", "length": 793 }, "evidence": [ { "id": "A0A8V0YB89", "url": "https://omabrowser.org/oma/group/A0A8V0YB89/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], "pmid": "" }, { "name": "axonemal A tubule inner sheath", "id": "GO:0160111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], "pmid": "" }, { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB89" } ], 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"categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Y9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGRLWRRGTASGRRSGGGGERQVLLWLVCVCVWESGAETLRYSVAEEMARDSLVGNVAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPEFPEKEMILEILETASPGTRFLLGNARDRDMGTNGLRNYSLSPNSHFSLNQGIGKGGGRYAELVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDGGGLSAHCRVHVEVLDVNDNAPEIALSSVSASIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEGEERPAVSVDAESGAVSVVRPLDYEEVRAVEVTVRAADGGSPPRSATALLVRVVVTTTRPWCCTRRPTAARRWASWCRGGPESRSPWADVFVVK", "length": 599, "header": "tr|A0A8V0Y9Q6-1|A0A8V0Y9Q6_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Y9Q6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q6/entry#A0A8V0Y9Q6-1", "sequence": { "sequence": "MKGRLWRRGTASGRRSGGGGERQVLLWLVCVCVWESGAETLRYSVAEEMARDSLVGNVAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPEFPEKEMILEILETASPGTRFLLGNARDRDMGTNGLRNYSLSPNSHFSLNQGIGKGGGRYAELVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDGGGLSAHCRVHVEVLDVNDNAPEIALSSVSASIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEGEERPAVSVDAESGAVSVVRPLDYEEVRAVEVTVRAADGGSPPRSATALLVRVVVTTTRPWCCTRRPTAARRWASWCRGGPESRSPWADVFVVK", "length": 599, "header": "tr|A0A8V0Y9Q6-1|A0A8V0Y9Q6_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Y9Q6-1" }, "locus": { "chromosome": "13", "start_pos": 1207085, "end_pos": 1195770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026567.1", "url": "https://www.ensembl.org/id/ENSGALT00010026567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015138.1", "url": "https://www.ensembl.org/id/ENSGALP00010015138.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Y9Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q6" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 143, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 429, "end_pos": 431 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9R6-1", "uniprot_ac": "A0A8V0Y9R6", "uniprot_id": "A0A8V0Y9R6_CHICK", "mass": { "chemical_mass": 21259.0, "monoisotopic_mass": 21259.0 }, "refseq": {}, "gene_names": [ { "name": "RAP1B", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ] } ], "protein_names": [ { "name": "RAP1B, member of RAS onco family", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAP1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6", "locus": { "chromosome": "1", "start_pos": 35372823, "end_pos": 35339888, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012538", "url": "https://www.ensembl.org/id/ENSGALG00010012538" } ] } } ], "crossref": [ { "id": "A0A8V0Y9R6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Y9R6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04175", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04175", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9R6", "url": "https://www.orthodb.org/?gene=A0A8V0Y9R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9S1", "url": "https://www.orthodb.org/?gene=A0A8V0Y9S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y9R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9S1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9S1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKVSVTTLLCLRNLNTSDCRRCCQEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL", "length": 187, "header": "tr|A0A8V0Y9R6-1|A0A8V0Y9R6_CHICK Isoform 1 of RAP1B, member of RAS onco family OS=Gallus gallus OX=9031 GN=RAP1B PE=4 SV=1 CANONICAL=A0A8V0Y9R6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6/entry#A0A8V0Y9R6-1", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKVSVTTLLCLRNLNTSDCRRCCQEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL", "length": 187, "header": "tr|A0A8V0Y9R6-1|A0A8V0Y9R6_CHICK Isoform 1 of RAP1B, member of RAS onco family OS=Gallus gallus OX=9031 GN=RAP1B PE=4 SV=1 CANONICAL=A0A8V0Y9R6-1" }, "locus": { "chromosome": "1", "start_pos": 35368014, "end_pos": 35358499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030064.1", "url": "https://www.ensembl.org/id/ENSGALT00010030064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017467.1", "url": "https://www.ensembl.org/id/ENSGALP00010017467.1" } ] } }, { "isoform_ac": "A0A8V0Y9S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6/entry#A0A8V0Y9S1-1", "sequence": { "sequence": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKVSQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL", "length": 186, "header": "tr|A0A8V0Y9S1-1|A0A8V0Y9S1_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAP1B PE=4 SV=1 CANONICAL=A0A8V0Y9R6-1" }, "locus": { "chromosome": "1", "start_pos": 35368014, "end_pos": 35358499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030074.1", "url": "https://www.ensembl.org/id/ENSGALT00010030074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017472.1", "url": "https://www.ensembl.org/id/ENSGALP00010017472.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of synaptic vesicle exocytosis", "id": "GO:2000301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9R6" } ], "pmid": "" }, { "name": "establishment of endothelial barrier", "id": "GO:0061028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9R6", "url": 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"https://www.uniprot.org/uniprotkb/Q9PSX7" } ] } ] }, { "uniprot_ac": "R4GJA4", "gene_name": "LOC770492", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "R4GJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "R4GJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.5.2", "ec_name": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "3.6.5.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2" }, { "id": "3.6.5.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.5.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9T7-1", "uniprot_ac": "A0A8V0Y9T7", "uniprot_id": "A0A8V0Y9T7_CHICK", "mass": { "chemical_mass": 68715.0, "monoisotopic_mass": 68715.0 }, "refseq": { "ac": "XP_040521108", "name": "oxidative stress-induced growth inhibitor 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521108" }, "gene_names": [ { "name": "OSGIN2", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7" } ] }, { "name": "OSGIN2", "type": "synonym", "evidence": [ { "id": "XP_040521108", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521108" } ] } ], "protein_names": [ { "name": "Oxidative stress induced growth inhibitor family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7/entry#names_and_taxonomy" } ] }, { "name": "oxidative stress-induced growth inhibitor 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040521108", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521108" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040521108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521108" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OSGIN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7", "locus": { "chromosome": "2", "start_pos": 123949925, "end_pos": 123935910, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012561", "url": "https://www.ensembl.org/id/ENSGALG00010012561" } ] } } ], "crossref": [ { "id": "A0A8V0Y9T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Y9T7", "database": "AlphaFoldDB", "categories": [] }, { "id": "420217", "url": "https://www.ncbi.nlm.nih.gov/gene/420217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420217", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCRCSLT", "url": "https://omabrowser.org/oma/group/CCRCSLT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9T7", "url": "https://www.orthodb.org/?gene=A0A8V0Y9T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9U2", "url": "https://www.orthodb.org/?gene=A0A8V0Y9U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG37", "url": "https://www.orthodb.org/?gene=A0A8V0YG37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI68", "url": "https://www.orthodb.org/?gene=A0A8V0YI68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15192:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15192:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040521108", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040521108", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRCCFCFVHVIAEELHVVRRQVCTDQFCTREIFSGGFFCFSLPSCEEVVFKPPCCLPVQLQSTERCCRSELGVQAGRNYNSSETEGQLLNSFGQYFGDSLGKKIKRMPLLEETVLPGDSVLTLPVVIIGNGPSGICLSYLLSGYRPYLSPEAVHPNPILHTKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHNYIPHIVLGKGPPGGAWHAMEGSMLTISFGDWMELPGLTFKDWAASKRRNIKSDRVMPEEIACYYKHYVKVMGLQKNFRDNVYITSVSRLYRGDDEDRSQLNENIPTQHLEMEDGQKPLIKRNWEVRGYQRATDGSHVPFCLFAENVALATGTFDSPGRLHVEGEDFPFVLHSMSDFGAAVSKGKLRGKADPVLIVGAGLTAADAVLCAYNNNIPVIHVFRRRVTDSSLIFKQLPKKLYPEYHKVYHMMCTQSHTGDSNLHSAYTSFPEHNVLSFKPEMKCVLQSASGLKKILKFSVALVLIGSHPNLFFLKDQGHSIGHHLNQPITCKGNPIEIDPYTYECTKEANLFALGPLVGDNFVRFLKGGALGIVRCLAIRQKKKHELTGSGDGGGDGVP", "length": 616, "header": "tr|A0A8V0Y9T7-1|A0A8V0Y9T7_CHICK Isoform 1 of Oxidative stress induced growth inhibitor family member 2 OS=Gallus gallus OX=9031 GN=OSGIN2 PE=4 SV=1 CANONICAL=A0A8V0Y9T7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7/entry#A0A8V0Y9T7-1", "sequence": { "sequence": "MRCCFCFVHVIAEELHVVRRQVCTDQFCTREIFSGGFFCFSLPSCEEVVFKPPCCLPVQLQSTERCCRSELGVQAGRNYNSSETEGQLLNSFGQYFGDSLGKKIKRMPLLEETVLPGDSVLTLPVVIIGNGPSGICLSYLLSGYRPYLSPEAVHPNPILHTKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHNYIPHIVLGKGPPGGAWHAMEGSMLTISFGDWMELPGLTFKDWAASKRRNIKSDRVMPEEIACYYKHYVKVMGLQKNFRDNVYITSVSRLYRGDDEDRSQLNENIPTQHLEMEDGQKPLIKRNWEVRGYQRATDGSHVPFCLFAENVALATGTFDSPGRLHVEGEDFPFVLHSMSDFGAAVSKGKLRGKADPVLIVGAGLTAADAVLCAYNNNIPVIHVFRRRVTDSSLIFKQLPKKLYPEYHKVYHMMCTQSHTGDSNLHSAYTSFPEHNVLSFKPEMKCVLQSASGLKKILKFSVALVLIGSHPNLFFLKDQGHSIGHHLNQPITCKGNPIEIDPYTYECTKEANLFALGPLVGDNFVRFLKGGALGIVRCLAIRQKKKHELTGSGDGGGDGVP", "length": 616, "header": "tr|A0A8V0Y9T7-1|A0A8V0Y9T7_CHICK Isoform 1 of Oxidative stress induced growth inhibitor family member 2 OS=Gallus gallus OX=9031 GN=OSGIN2 PE=4 SV=1 CANONICAL=A0A8V0Y9T7-1" }, "locus": { "chromosome": "2", "start_pos": 123946766, "end_pos": 123936848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030102.1", "url": "https://www.ensembl.org/id/ENSGALT00010030102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017487.1", "url": "https://www.ensembl.org/id/ENSGALP00010017487.1" } ] } }, { "isoform_ac": "A0A8V0Y9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7/entry#A0A8V0Y9U2-1", "sequence": { "sequence": "MFTRVFFHLSFSIRNYNSSETEGQLLNSFGQYFGDSLGKKIKRMPLLEETVLPGDSVLTLPVVIIGNGPSGICLSYLLSGYRPYLSPEAVHPNPILHTKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHNYIPHIVLGKGPPGGAWHAMEGSMLTISFGDWMELPGLTFKDWAASKRRNIKSDRVMPEEIACYYKHYVKVMGLQKNFRDNVYITSVSRLYRGDDEDRSQLNENIPTQHLEMEDGQKPLIKRNWEVRGYQRATDGSHVPFCLFAENVALATGTFDSPGRLHVEGEDFPFVLHSMSDFGAAVSKGKLRGKADPVLIVGAGLTAADAVLCAYNNNIPVIHVFRRRVTDSSLIFKQLPKKLYPEYHKVYHMMCTQSHTGDSNLHSAYTSFPEHNVLSFKPEMKCVLQSASGLKKILKFSVALVLIGSHPNLFFLKDQGHSIGHHLNQPITCKGNPIEIDPYTYECTKEANLFALGPLVGDNFVRFLKGGALGIVRCLAIRQKKKHELTGSGDGGGDGVP", "length": 553, "header": "tr|A0A8V0Y9U2-1|A0A8V0Y9U2_CHICK Computationally mapped isoform of Oxidative stress induced growth inhibitor family member 2 OS=Gallus gallus OX=9031 GN=OSGIN2 PE=4 SV=1 CANONICAL=A0A8V0Y9T7-1" }, "locus": { "chromosome": "2", "start_pos": 123946766, "end_pos": 123936501, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030110.1", "url": "https://www.ensembl.org/id/ENSGALT00010030110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017492.1", "url": "https://www.ensembl.org/id/ENSGALP00010017492.1" } ] } }, { "isoform_ac": "A0A8V0YG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7/entry#A0A8V0YG37-1", "sequence": { "sequence": "MPVWCCRCSLAGPVSLPSCEEVVFKPPCCLPVQLQSTERCCRSELGVQAGRNYNSSETEGQLLNSFGQYFGDSLGKKIKRMPLLEETVLPGDSVLTLPVVIIGNGPSGICLSYLLSGYRPYLSPEAVHPNPILHTKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHNYIPHIVLGKGPPGGAWHAMEGSMLTISFGDWMELPGLTFKDWAASKRRNIKSDRVMPEEIACYYKHYVKVMGLQKNFRDNVYITSVSRLYRGDDEDRSQLNENIPTQHLEMEDGQKPLIKRNWEVRGYQRATDGSHVPFCLFAENVALATGTFDSPGRLHVEGEDFPFVLHSMSDFGAAVSKGKLRGKADPVLIVGAGLTAADAVLCAYNNNIPVIHVFRRRVTDSSLIFKQLPKKLYPEYHKVYHMMCTQSHTGDSNLHSAYTSFPEHNVLSFKPEMKCVLQSASGLKKILKFSVALVLIGSHPNLFFLKDQGHSIGHHLNQPITCKGNPIEIDPYTYECTKEANLFALGPLVGDNFVRFLKGGALGIVRCLAIRQKKKHELTGSGDGGGDGVP", "length": 590, "header": "tr|A0A8V0YG37-1|A0A8V0Y9T7_CHICK Computationally mapped isoform of Oxidative stress induced growth inhibitor family member 2 OS=Gallus gallus OX=9031 GN=OSGIN2 PE=4 SV=1 CANONICAL=A0A8V0Y9T7-1" }, "locus": { "chromosome": "2", "start_pos": 123946766, "end_pos": 123936009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030105.1", "url": "https://www.ensembl.org/id/ENSGALT00010030105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017489.1", "url": "https://www.ensembl.org/id/ENSGALP00010017489.1" } ] } }, { "isoform_ac": "A0A8V0YI68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7/entry#A0A8V0YI68-1", "sequence": { "sequence": "MPVWCCRCSLAGPVSSETEGQLLNSFGQYFGDSLGKKIKRMPLLEETVLPGDSVLTLPVVIIGNGPSGICLSYLLSGYRPYLSPEAVHPNPILHTKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHNYIPHIVLGKGPPGGAWHAMEGSMLTISFGDWMELPGLTFKDWAASKRRNIKSDRVMPEEIACYYKHYVKVMGLQKNFRDNVYITSVSRLYRGDDEDRSQLNENIPTQHLEMEDGQKPLIKRNWEVRGYQRATDGSHVPFCLFAENVALATGTFDSPGRLHVEGEDFPFVLHSMSDFGAAVSKGKLRGKADPVLIVGAGLTAADAVLCAYNNNIPVIHVFRRRVTDSSLIFKQLPKKLYPEYHKVYHMMCTQSHTGDSNLHSAYTSFPEHNVLSFKPEMKCVLQSASGLKKILKFSVALVLIGSHPNLFFLKDQGHSIGHHLNQPITCKGNPIEIDPYTYECTKEANLFALGPLVGDNFVRFLKGGALGIVRCLAIRQKKKHELTGSGDGGGDGVP", "length": 550, "header": "tr|A0A8V0YI68-1|A0A8V0Y9T7_CHICK Computationally mapped isoform of Oxidative stress induced growth inhibitor family member 2 OS=Gallus gallus OX=9031 GN=OSGIN2 PE=4 SV=1 CANONICAL=A0A8V0Y9T7-1" }, "locus": { "chromosome": "2", "start_pos": 123946766, "end_pos": 123936009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030117.1", "url": "https://www.ensembl.org/id/ENSGALT00010030117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017495.1", "url": "https://www.ensembl.org/id/ENSGALP00010017495.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420217", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420217", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZB49-1", "protein_name": "Oxidative stress induced growth inhibitor family member 2", "gene_name": "Osgin2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVWCCRCSLAGHFRNYSDTETEGEIFNSLVQYLGDNLGPKVKGMPLVEETSLLEDSSVTLPMVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNAILHSKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDSPSILHWKLEQHHSIPHLVLGKGPPGGAWHNMEGSMLTISFGNWMELPGLKFKDWISSKRRNLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQGDNGSQDRDISAKHLQNQKSKFIKRNWEIRGYQRVAGGSHVPFCLFAENVALATGTLDSPAHLEVEGEEFPFVFHSMPEFGAAINSGKLCGRVDPVLIVGSGLTAADAVLCAYNNNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSADSDHLSDYTSFPEHRVLSFKSDMKCILQSVSGLKKIFKLSAAVILIGSHPNLSFLKEQGCYLGRNSSQPISCKGNPVEIDAYTYECVKEANLFALGPLVGDNFVRFLKGGALGVTRCLVTRQKKKQHLFVQRGGGDGVA", "length": 550 }, "evidence": [ { "id": "A0A8V0Y9T7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9T7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7GQS8-1", "protein_name": "Oxidative stress induced growth inhibitor family member 2", "gene_name": "OSGIN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPVWCCRCSLAGHFRNYSDTETEGEIFNSLVQYFGDNLGRKVKAMPLVEETSLLEDSSVTLPVVVIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILHSKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHLVLGKGPPGGAWHNMEGSRLTISFGNWMELPGLKFKDWVSTKRRNLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQVDNDGQDRDISTPHLQIEKSKFIKRNWEIRGYQRIAEGSHVPFCLFAENVALATGTLDSPGRLEIEGEDFPFVFHSMPEFGAAISKGKLRGKVDPVLIVGSGLTAADAVLCAYNNNVPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSLDSNLLSDYTSFPEHHVLSFKSDMKCILQNISGLKKIFKLSAAVVLIGSHPNLSFLKEQGCYLGHNSSQPITCKGNPVEIDAYTYECVKEANLFALGPLVGDNFVRFLKGGALGVTRCLATRQKKKQHLFVERGGGDGIA", "length": 550 }, "evidence": [ { "id": "A0A8V0Y9T7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9T7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9Y236-1", "protein_name": "Oxidative stress-induced growth inhibitor 2", "gene_name": "OSGIN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHVVLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGYQRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLSFLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALGVTRCLATRQKKKHLFVERGGGDGIA", "length": 505 }, "evidence": [ { "id": "A0A8V0Y9T7", "url": "https://omabrowser.org/oma/group/A0A8V0Y9T7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9T7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9T7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9U9-1", "uniprot_ac": "A0A8V0Y9U9", "uniprot_id": "A0A8V0Y9U9_CHICK", "mass": { "chemical_mass": 30552.0, "monoisotopic_mass": 30552.0 }, "refseq": { "ac": "XP_040545696", "name": "stathmin domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545696" }, "gene_names": [ { "name": "STMND1", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U9" } ] }, { "name": "STMND1", "type": "synonym", "evidence": [ { "id": "XP_040545696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545696" } ] } ], "protein_names": [ { "name": "Stathmin domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U9/entry#names_and_taxonomy" } ] }, { "name": "stathmin domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040545696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545696" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040545696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545696" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STMND1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U9", "locus": {} } ], "crossref": [ { "id": "A0A8V0Y9U9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Y9U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747319", "url": "https://www.ncbi.nlm.nih.gov/gene/101747319", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "LNKMPQH", "url": "https://omabrowser.org/oma/group/LNKMPQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9U9", "url": "https://www.orthodb.org/?gene=A0A8V0Y9U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_040545696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCNTSNRVAAAQLSSEELQNNHEARSQTPSDSADRTWAATSQEGAAWTRGTSENGSKLEVEAREGDFPERSTEGFAPSEKSSNAQSTDTLLTSGFISKSWPLQETERQKSSDILEELRMQGIIRSQSTTASTEEAYENKRDALEKMLKKPPARLEKMWFGSKEENDFTAKDMKTAEEKNKQVREKELRRTPQHTASYPATDHQTTGKQTEKDCPSFQSQESTDAPQSSPLHGEISVPLQEITAEETTNYYTEDFTIESDITYNCINETIWI", "length": 272, "header": "tr|A0A8V0Y9U9-1|A0A8V0Y9U9_CHICK Isoform 1 of Stathmin domain containing 1 OS=Gallus gallus OX=9031 GN=STMND1 PE=4 SV=1 CANONICAL=A0A8V0Y9U9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9U9/entry#A0A8V0Y9U9-1", "sequence": { "sequence": "MGCNTSNRVAAAQLSSEELQNNHEARSQTPSDSADRTWAATSQEGAAWTRGTSENGSKLEVEAREGDFPERSTEGFAPSEKSSNAQSTDTLLTSGFISKSWPLQETERQKSSDILEELRMQGIIRSQSTTASTEEAYENKRDALEKMLKKPPARLEKMWFGSKEENDFTAKDMKTAEEKNKQVREKELRRTPQHTASYPATDHQTTGKQTEKDCPSFQSQESTDAPQSSPLHGEISVPLQEITAEETTNYYTEDFTIESDITYNCINETIWI", "length": 272, "header": "tr|A0A8V0Y9U9-1|A0A8V0Y9U9_CHICK Isoform 1 of Stathmin domain containing 1 OS=Gallus gallus OX=9031 GN=STMND1 PE=4 SV=1 CANONICAL=A0A8V0Y9U9-1" }, "locus": { "chromosome": "2", "start_pos": 61623395, "end_pos": 61613739, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026634.1", "url": "https://www.ensembl.org/id/ENSGALT00010026634.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015188.1", "url": "https://www.ensembl.org/id/ENSGALP00010015188.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"tr|A0A8V0Y9X3-1|A0A8V0Y9X3_CHICK Isoform 1 of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Y9X3-1" }, "locus": { "chromosome": "W", "start_pos": 1526753, "end_pos": 1325872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027552.1", "url": "https://www.ensembl.org/id/ENSGALT00010027552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015780.1", "url": "https://www.ensembl.org/id/ENSGALP00010015780.1" } ] } }, { "isoform_ac": "A0A8V0YIB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X3/entry#A0A8V0YIB8-1", "sequence": { "sequence": "MDWPEGKKFETSPGEEVSRAKEAPPYNELPGNEKKYALFTDGSCRIVGKYRRWKAAVWSPVRQVAEAPPYNELPGNEKKYALFTDGSCRIVGKYRRWKAAVWSPVRQVAEATEGKGESSQFAEVKAVQLALDVAEREGWPVLYLYTDSWMVANALWGWLQQWEQNNWQRRGKPIWSAELWKDIAARIKNMVVKVRHVDAHVPKSRATEEQKNNHQVDQAAKIEVAQIDLDWQNKGELFLARWAHETSGHQGRDATYKWARDRGVDLTMDAIAQVIHDCETCAIIKQA", "length": 287, "header": "tr|A0A8V0YIB8-1|A0A8V0YIB8_CHICK Computationally mapped isoform of RNase H type-1 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Y9X3-1" }, "locus": { "chromosome": "W", "start_pos": 1526627, "end_pos": 1104577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027554.1", "url": "https://www.ensembl.org/id/ENSGALT00010027554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015782.1", "url": "https://www.ensembl.org/id/ENSGALP00010015782.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X3" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Y9X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X3" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 267, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9X4-1", "uniprot_ac": "A0A8V0Y9X4", "uniprot_id": "A0A8V0Y9X4_CHICK", "mass": { "chemical_mass": 96543.0, "monoisotopic_mass": 96543.0 }, "refseq": { "ac": "XP_003643002", "name": "dimethylglycine dehydrogenase, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643002" }, "gene_names": [ { "name": "DMGDH", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ] }, { "name": "DMGDH", "type": "synonym", "evidence": [ { "id": "XP_003643002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643002" } ] } ], "protein_names": [ { "name": "Dimethylglycine dehydrogenase, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4/entry#names_and_taxonomy" } ] }, { "name": "1.5.8.4", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4/entry#names_and_taxonomy" } ] }, { "name": "ME2GLYDH", "type": "synonym", "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4/entry#names_and_taxonomy" } ] }, { "name": "dimethylglycine dehydrogenase, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003643002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643002" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643002.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643002" } ] }, { "annotation": "Catalyzes the demethylation of N,N-dimethylglycine to sarcosine. Also has activity with sarcosine in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4#function" }, { "database": "UniProtKB", "id": "ARBA00055666", "url": "https://www.uniprot.org/uniprotkb/ARBA00055666#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DMGDH", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4", "locus": { "chromosome": "Z", "start_pos": 23037335, "end_pos": 22991586, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012599", "url": "https://www.ensembl.org/id/ENSGALG00010012599" } ] } } ], "crossref": [ { "id": "A0A8V0Y9X4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Y9X4", "database": "AlphaFoldDB", "categories": [] }, { "id": "416370", "url": "https://www.ncbi.nlm.nih.gov/gene/416370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416370", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416370", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGWERPN", "url": "https://omabrowser.org/oma/group/NGWERPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9X4", "url": "https://www.orthodb.org/?gene=A0A8V0Y9X4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN23", "url": "https://www.orthodb.org/?gene=A0A8V0YN23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43757", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43757", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43757:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43757:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003643002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643002", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "52856", "url": "https://www.rhea-db.org/rhea/52856", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAMLRAALRRLPLPCRGGRPGPSAALRALGGAASARAGKENRSPSLGKDKADTVIIGGGCVGVSLAYHLAKAGLQDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHAYSIKLYEKLEEETGQAVGFHQPGSIRIASTPTRVDEFKYQMTRAGWHPTEQYLITPEKVQELFPLLNMDKVLAGLYNPGDGHIDPYSLTMALAAGARKYGAQLNYPVQVTNLNSRSDGTWEVETPLGVIQAKRIVNTAGFWAHEIGKMIGLQHPVIPVHHQYVVTSTVPEVKALKTELPVIRDLEGSYYLRQERDGLLFGPYESQEKMKLQDSWVTNGVPPGFGKELFESDLDRIMEYVEAAMEMVPVLKKANIINTVSGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGIGKYLSDWILEGEPPFDLIELDPNRYGKWTTTEYTAAKARESYGFNNIIIYPKEERFAGRPTERTSGLYDLLKTKCSMGFHAGWEQPHWFYKPGDETGYKPSFRRTNWFDPVGREYKQVMERVGVIDLSPFGKFKVKGTDSVKLLDHLFANVVPKVGSTNISHMLTPKGKVYAELTVSQLYPGEFMLVTGSGSELHDLRWIEEEVVRGGYKVEIENMTDEMGVLGVAGPYARQVLQRLTAEDLSDGSFKFLQSRHLKLSDIAVTAIRISYTGELGWELYHRKEDSVALYNAIMDAGQKEGIDNFGTYALNALRLEKGFRAWGAEMNCDTNPLEAGLEYFVKLNKPADFIGKKMLKQIKEKGLKRRLVYLTLETDDVDPEGNESVWHNGKVIGNTTSGSFSYSAKQSLAFAYVPTELSKVGQKLEVELLGKNYSATIIQEPLVLTEPTRTRLQRKGQSPKI", "length": 868, "header": "tr|A0A8V0Y9X4-1|A0A8V0Y9X4_CHICK Isoform 1 of Dimethylglycine dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=DMGDH PE=1 SV=1 CANONICAL=A0A8V0Y9X4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9X4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4/entry#A0A8V0Y9X4-1", "sequence": { "sequence": "MSAMLRAALRRLPLPCRGGRPGPSAALRALGGAASARAGKENRSPSLGKDKADTVIIGGGCVGVSLAYHLAKAGLQDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHAYSIKLYEKLEEETGQAVGFHQPGSIRIASTPTRVDEFKYQMTRAGWHPTEQYLITPEKVQELFPLLNMDKVLAGLYNPGDGHIDPYSLTMALAAGARKYGAQLNYPVQVTNLNSRSDGTWEVETPLGVIQAKRIVNTAGFWAHEIGKMIGLQHPVIPVHHQYVVTSTVPEVKALKTELPVIRDLEGSYYLRQERDGLLFGPYESQEKMKLQDSWVTNGVPPGFGKELFESDLDRIMEYVEAAMEMVPVLKKANIINTVSGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGIGKYLSDWILEGEPPFDLIELDPNRYGKWTTTEYTAAKARESYGFNNIIIYPKEERFAGRPTERTSGLYDLLKTKCSMGFHAGWEQPHWFYKPGDETGYKPSFRRTNWFDPVGREYKQVMERVGVIDLSPFGKFKVKGTDSVKLLDHLFANVVPKVGSTNISHMLTPKGKVYAELTVSQLYPGEFMLVTGSGSELHDLRWIEEEVVRGGYKVEIENMTDEMGVLGVAGPYARQVLQRLTAEDLSDGSFKFLQSRHLKLSDIAVTAIRISYTGELGWELYHRKEDSVALYNAIMDAGQKEGIDNFGTYALNALRLEKGFRAWGAEMNCDTNPLEAGLEYFVKLNKPADFIGKKMLKQIKEKGLKRRLVYLTLETDDVDPEGNESVWHNGKVIGNTTSGSFSYSAKQSLAFAYVPTELSKVGQKLEVELLGKNYSATIIQEPLVLTEPTRTRLQRKGQSPKI", "length": 868, "header": "tr|A0A8V0Y9X4-1|A0A8V0Y9X4_CHICK Isoform 1 of Dimethylglycine dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=DMGDH PE=1 SV=1 CANONICAL=A0A8V0Y9X4-1" }, "locus": { "chromosome": "Z", "start_pos": 23036790, "end_pos": 22991653, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030179.1", "url": "https://www.ensembl.org/id/ENSGALT00010030179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017523.1", "url": "https://www.ensembl.org/id/ENSGALP00010017523.1" } ] } }, { "isoform_ac": "A0A8V0YN23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4/entry#A0A8V0YN23-1", "sequence": { "sequence": "MLRAALRRLPLPCRGGRPGPSAALRALGGAASARAGKENRSPSLGKDKADTVIIGGGCVGVSLAYHLAKAGLQDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHAYSIKLYEKLEEETGQAVGFHQPGSIRIASTPTRVDEFKYQMTRAGWHPTEQYLITPEKVQELFPLLNMDKVLAGLYNPGDGHIDPYSLTMALAAGARKYGAQLNYPVQVTNLNSRSDGTWEVETPLGVIQAKRIVNTAGFWAHEIGKMIGLQHPVIPVHHQYVVTSTVPEVKALKTELPVIRDLEGSYYLRQERDGLLFGPYESQEKMKLQDSWVTNGVPPGFGKELFESDLDRIMEYVEAAMEMVPVLKKANIINTVSGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGIGKYLSDWILEGEPPFDLIELDPNRYGKWTTTEYTAAKARESYGFNNIIIYPKEERFAGRPTERTSGLYDLLKTKCSMGFHAGWEQPHWFYKPGDETGYKPSFRRTNWFDPVGREYKQVMERVGVIDLSPFGKFKVKGTDSVKLLDHLFANVVPKVGSTNISHMLTPKGKVYAELTVSQLYPGEFMLVTGSGSELHDLRWIEEEVVRGGYKVEIENMTDEMGVLGVAGPYARQVLQRLTAEDLSDGSFKFLQSRHLKLSDIAVTAIRISYTGELGWELYHRKEDSVALYNAIMDAGQKEGIDNFGTYALNALRLEKGFRAWGAEMNCDTNPLEAGLEYFVKLNKPADFIGKKMLKQIKEKGLKRRLVYLTLETDDVDPEGNESVWHNGKGAKTYQLKVMPFTKNVMNSTMHLKFTSHMKYTTQD", "length": 829, "header": "tr|A0A8V0YN23-1|A0A8V0Y9X4_CHICK Computationally mapped isoform of Dimethylglycine dehydrogenase, mitochondrial OS=Gallus gallus OX=9031 GN=DMGDH PE=1 SV=1 CANONICAL=A0A8V0Y9X4-1" }, "locus": { "chromosome": "Z", "start_pos": 23036451, "end_pos": 22991662, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030175.1", "url": "https://www.ensembl.org/id/ENSGALT00010030175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017519.1", "url": "https://www.ensembl.org/id/ENSGALP00010017519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416370", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416370", "resource": "KEGG Pathway" }, { "id": "R-GGA-6798163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798163", "resource": "Reactome", "description": "Choline catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "Q63342-1", "protein_name": "Dimethylglycine dehydrogenase, mitochondrial", "gene_name": "Dmgdh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLGALRLRGLALRSSQGRPSSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS", "length": 857 }, "evidence": [ { "id": "A0A8V0Y9X4", "url": "https://omabrowser.org/oma/group/A0A8V0Y9X4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DBT9-1", "protein_name": "Dimethylglycine dehydrogenase, mitochondrial", "gene_name": "Dmgdh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRPGALRLRGLALRGSPRRPSSAGLREGQESPASPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLMEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMNKILAGLYNPGDGHIDPYSLTMALAAGARKYGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVTHGVPPGFGKELFESDLDRISDHLEAAMEMIPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVATGFGYGIIHAGGVGKFLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYKTLKSKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGRDSTQLLDHLFANVIPKVGFTNISHMLTPRGRVYAELTVSQQSPGEFLLITGSGSELHDLRWIEEAAFRGGYDVEIQNITDEFGVLGVAGPYARRVLQKLTSEDLSDDAFKFLQTKSFNISDIPVTAIRISYTGELGWELYHRREDSATLYERIMSAGQEEGIGDFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKTEGLKRRLVCLTVATDDVDPEGNESIWYKGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPATIIQEPLVLTEPARARLQKDGKKTNLEKGPSRTTKL", "length": 869 }, "evidence": [ { "id": "A0A8V0Y9X4", "url": "https://omabrowser.org/oma/group/A0A8V0Y9X4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UI17-1", "protein_name": "Dimethylglycine dehydrogenase, mitochondrial", "gene_name": "DMGDH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRPGAQLLRGLLLRSCPLQGSPGRPRSVCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT", "length": 866 }, "evidence": [ { "id": "A0A8V0Y9X4", "url": "https://omabrowser.org/oma/group/A0A8V0Y9X4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "choline catabolic process", "id": "GO:0042426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dimethylglycine dehydrogenase activity", "id": "GO:0047865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9X4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "52856", "name": "", "equation": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + reduced [electron-transfer flavoprotein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y9X4-1" ], "evidence": [ { "id": "52856", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52856" } ] }, { "id": "R-GGA-6797653", "name": "DMGDH:FAD oxidatively demethylates DMGLY to SARC", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-6797923", "R-ALL-9979086" ], "output_participant_list": [ "R-ALL-6797917", "R-ALL-9979072" ], "enzyme_list": [ "A0A8V0Y9X4-1" ], "evidence": [ { "id": "R-GGA-6797653", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6797653" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6797917", "participant_name": "SARC [mitochondrial matrix]", "crossref": [ { "id": "ZINC000004658561", "database": "ZINC", "url": "" }, { "id": "57433", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6797923", "participant_name": "DMGLY [mitochondrial matrix]", "crossref": [ { "id": "58251", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895466", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9979072", "participant_name": "MeTHFpolyGlu [mitochondrial matrix]", "crossref": [ { "id": "136572", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9979086", "participant_name": "THFpolyGlu [mitochondrial matrix]", "crossref": [ { "id": "141005", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y9X4", "gene_name": "DMGDH", "activity": [ { "ec_number": "1.5.8.4", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ] }, { "ec_number": "1.5.8.4", "activity": "", "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" }, { "id": "PF08669", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08669" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminomethyltransferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 772, "end_pos": 850, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" }, { "id": "PF01266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 416, "start_aa": "Asp", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" }, { "id": "PF16350", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16350" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD dependent oxidoreductase central", "eco_id": "ECO_0000259", "start_pos": 419, "end_pos": 472, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Y9X4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9X4" }, { "id": "PF01571", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01571" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GCVT N-terminal", "eco_id": "ECO_0000259", "start_pos": 481, "end_pos": 752, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.8.4", "ec_name": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "1.5.8.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.8.4" }, { "id": "1.5.8.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.8.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 801, "end_pos": 803 }, { "start_pos": 839, "end_pos": 841 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Y9Y3-1", "uniprot_ac": "A0A8V0Y9Y3", "uniprot_id": "A0A8V0Y9Y3_CHICK", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35001:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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The reference sequence was derived from JAENSK010000040.1. 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"MAESGTEPGTARSGAGAAAMAGGAQDGSDGGGEAAPASPPPPPPCSAPTAAGTDDGGKALSAAEYARRVHQWLWDSYCGYLSWHYGLPALLAAGPAARLAAPPPPPSAPPGAAPAAYYSPFYLFAPPPAAAAAAPGSRAPPAPAPASSWSAAAARLSPLPRAAPGSGSGGAAPREAAGRPAGREFIIPSLAHRFIAEMVDFFILFFIKATIVLSIMHLSGIKDISKFAMHYIIEEIDEDTSMEDLQKMMIVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSSNVSMTTSTIRALIKNFSIASFFPAFITLLFFQHNRTAYDIVAGTIVVRRNGIR", "length": 357, "header": "tr|A0A8V0Y9Z8-1|A0A8V0Y9Z8_CHICK Isoform 1 of Family with sequence similarity 8 member A1 OS=Gallus gallus OX=9031 GN=FAM8A1 PE=4 SV=1 CANONICAL=A0A8V0Y9Z8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y9Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z8/entry#A0A8V0Y9Z8-1", "sequence": { "sequence": "MAESGTEPGTARSGAGAAAMAGGAQDGSDGGGEAAPASPPPPPPCSAPTAAGTDDGGKALSAAEYARRVHQWLWDSYCGYLSWHYGLPALLAAGPAARLAAPPPPPSAPPGAAPAAYYSPFYLFAPPPAAAAAAPGSRAPPAPAPASSWSAAAARLSPLPRAAPGSGSGGAAPREAAGRPAGREFIIPSLAHRFIAEMVDFFILFFIKATIVLSIMHLSGIKDISKFAMHYIIEEIDEDTSMEDLQKMMIVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSSNVSMTTSTIRALIKNFSIASFFPAFITLLFFQHNRTAYDIVAGTIVVRRNGIR", "length": 357, "header": "tr|A0A8V0Y9Z8-1|A0A8V0Y9Z8_CHICK Isoform 1 of Family with sequence similarity 8 member A1 OS=Gallus gallus OX=9031 GN=FAM8A1 PE=4 SV=1 CANONICAL=A0A8V0Y9Z8-1" }, "locus": { "chromosome": "2", "start_pos": 61768067, "end_pos": 61761891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026733.1", "url": "https://www.ensembl.org/id/ENSGALT00010026733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015246.1", "url": "https://www.ensembl.org/id/ENSGALP00010015246.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", 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"MAEGPEEARGHPPGQDDGGGDHEPVPSLRGPPTTAVPCPRDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASGSGAELQEQAGCEAPEAAAPRERPARLSAREYSRQVHEWLWQSYCGYLTWHSGLAAFPAYCSPQPSPQSFPSGGAAVPQAAAPPPPQLGYYNPFYFLSPGAAGPDPRTAAGISTPAPVAGLGPRAPHVQASVRATPVTRVGSAAPSRSPSETGRQAGREYVIPSLAHRFMAEMVDFFILFFIKATIVLSIMHLSGIKDISKFAMHYIIEEIDEDTSMEDLQKMMVVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSSNVSITTSTIRALIKNFSIASFFPAFITLLFFQHNRTAYDIVAGTIVVKRNGVR", "length": 413 }, "evidence": [ { "id": "A0A8V0Y9Z8", "url": "https://omabrowser.org/oma/group/A0A8V0Y9Z8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Hrd1p ubiquitin ligase complex", "id": "GO:0000836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000836", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Y9Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Z8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA18-1", "uniprot_ac": "A0A8V0YA18", "uniprot_id": "A0A8V0YA18_CHICK", "mass": { "chemical_mass": 69262.0, "monoisotopic_mass": 69262.0 }, "refseq": { "ac": "XP_015140664", "name": "XK-related protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140664" }, "gene_names": [ { "name": "XKR6", "type": "recommended", "evidence": [ { "id": "A0A8V0YA18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18" } ] }, { "name": "XKR6", "type": "synonym", "evidence": [ { "id": "XP_015140664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140664" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YA18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 6", "type": "synonym", "evidence": [ { "id": "XP_015140664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140664" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015140664.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140664" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18", "locus": { "chromosome": "3", "start_pos": 106741436, "end_pos": 106890086, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011213", "url": "https://www.ensembl.org/id/ENSGALG00010011213" } ] } } ], "crossref": [ { "id": "A0A8V0YA18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YA18", "database": "AlphaFoldDB", "categories": [] }, { "id": "422029", "url": "https://www.ncbi.nlm.nih.gov/gene/422029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422029", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWVWQTI", "url": "https://omabrowser.org/oma/group/VWVWQTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA18", "url": "https://www.orthodb.org/?gene=A0A8V0YA18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16024:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16024:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015140664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAKSDGGGGGVGFAQLHNLDEAAAAAAAAGVCGGVGAAAAEGAEEPGGSSSLHICHCCNTSSCYWGCRSACLRSLFGRAAAAAAAEPLAPRPADEGAPRAPEVGGAGERPWLDCLWIVLALLVLLGDVGTDLWLALHHYGRRDYVWCGLTLAFVLLPSVLVQILSFRWFVQDYTGGGLGAVQGLSSRGPPMMGAAGRRGGPGGVGGAAGTATPGAQRLCRISVWVWQSVIHLLQMGQVWRYIRTMYLGIQSQRRKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKNRAETLPCVSSVASLMSLAWVLASYHKLLRDSRDDKKSMSYRGALIHLFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTVVLTENAALTLLWYFYRDPDTTDSYAVPALCCVFLSFAAGIALMLLYYGVLHPMGPRAKIFASSCCAELLWGIPLPPDVEPMAPQTPGYRGAQATPTRAVTEQQEELTADTCLPVFQVRAMVPSTPSGRPYPPEGPLIKIDIPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL", "length": 627, "header": "tr|A0A8V0YA18-1|A0A8V0YA18_CHICK Isoform 1 of XK-related protein OS=Gallus gallus OX=9031 GN=XKR6 PE=3 SV=1 CANONICAL=A0A8V0YA18-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18/entry#A0A8V0YA18-1", "sequence": { "sequence": "MAAKSDGGGGGVGFAQLHNLDEAAAAAAAAGVCGGVGAAAAEGAEEPGGSSSLHICHCCNTSSCYWGCRSACLRSLFGRAAAAAAAEPLAPRPADEGAPRAPEVGGAGERPWLDCLWIVLALLVLLGDVGTDLWLALHHYGRRDYVWCGLTLAFVLLPSVLVQILSFRWFVQDYTGGGLGAVQGLSSRGPPMMGAAGRRGGPGGVGGAAGTATPGAQRLCRISVWVWQSVIHLLQMGQVWRYIRTMYLGIQSQRRKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKNRAETLPCVSSVASLMSLAWVLASYHKLLRDSRDDKKSMSYRGALIHLFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTVVLTENAALTLLWYFYRDPDTTDSYAVPALCCVFLSFAAGIALMLLYYGVLHPMGPRAKIFASSCCAELLWGIPLPPDVEPMAPQTPGYRGAQATPTRAVTEQQEELTADTCLPVFQVRAMVPSTPSGRPYPPEGPLIKIDIPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL", "length": 627, "header": "tr|A0A8V0YA18-1|A0A8V0YA18_CHICK Isoform 1 of XK-related protein OS=Gallus gallus OX=9031 GN=XKR6 PE=3 SV=1 CANONICAL=A0A8V0YA18-1" }, "locus": { "chromosome": "3", "start_pos": 106890049, "end_pos": 106742440, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026782.1", "url": "https://www.ensembl.org/id/ENSGALT00010026782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015266.1", "url": "https://www.ensembl.org/id/ENSGALP00010015266.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422029", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q6C8-1", "protein_name": "XK-related protein 6", "gene_name": "Xkr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAKSDGGGVGVGFAQLHNLDEAVGSGEEDGEPGGGGCGGGDGSEPGESSSLHICHCCNTSSCYWGCRSACLRSLLGKKPRRSAAAADGGDQPLQPPGAAGRHPPTPSAGRPQPASPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYGCFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLSSRGPPMMGAGYGHGAARGGPGAGGSATPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRQKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKNSAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGALIHLFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRNPESTDSYAVPALCCVFVSFVAGITLMLLYYGVLHPMGPRAKVFASSCCAELLWGIPLPPDVEPMAPQTPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPSTPSGRPYHPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL", "length": 638 }, "evidence": [ { "id": "A0A8V0YA18", "url": "https://omabrowser.org/oma/group/A0A8V0YA18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1R8C3-1", "protein_name": "XK-related protein", "gene_name": "xkr6b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAKSDGRGVATGFAQLHNLDEAVGSCEDDPRQGSSFHICHCCNTSSCYWGCRSACLHYLLDKGRDVRRPPHEERLWLDCLWIVLALLVFFWDVGTDLWLALDYYAKQDYLWFGLTLFFVLVPSVLVQILSFRWFVQDYTGGGLGSVEGLSSTRRSTSAVVYNRARCCRVSVWVWQTLIHILQMGQVWRYIRTMYLGIQSRRQKENQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKNRAETLQCVSAVTSLLSLSWVLASYHKLLRDSRDDQKSMSYRGALVHLLWRFFTISSRALSFALFASVFHLYFGIFVVLHWCAMAFWVIHGGTDFCMSKWEEVLFNMVVGVVYVFCWFNVKEGRTRYRMVFYYSLVLVENTILTALWYAYRDPVSTDSYAASALCGVFLCFASGVACMVLYYGVLHPMGPRLRVLASSCCAELLWGLPLPPEAEPMAPTPGPRGSQATPTRGMASGDYSEPEEAATDTCLPVFQVRSTEPTDASGRPIPPKGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQFISPNAVGIRYRDGPLLYELLQYESSL", "length": 578 }, "evidence": [ { "id": "A0A8V0YA18", "url": "https://omabrowser.org/oma/group/A0A8V0YA18/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5GH57-1", "protein_name": "XK-related protein 6", "gene_name": "Xkr6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAKSDGGGVGVGFAQLHNLDEAVGSGEEDGEPGGGGCGGGDGSEPGESSSLHICHCCNTSSCYWGCRSACLRSLLGKKPRRSAAAADGGDQPLQPPGAAGRHPPTPSAGRPQPASPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYGCFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLSSRGPPMMGAGYGHGAARGGPGAGGSATPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRQKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLCIMIQKNSAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGALIHLFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRNPESTDSYAVPALCCVFVSFVAGITLMLLYYGVLHPMGPRAKVFASSCCAELLWGIPLPPDVEPMAPQTPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPSTPSGRPYHPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL", "length": 638 }, "evidence": [ { "id": "A0A8V0YA18", "url": "https://omabrowser.org/oma/group/A0A8V0YA18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GH73-1", "protein_name": "XK-related protein 6", "gene_name": "XKR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAKSDGGGVGVGFAQLHNLDEAVGSGGEEDGEPGGGGCGGGGDGSEPGESSSMHICHCCNTSSCYWGCRSACLRSLLGRKPRRSAAADGGDQPLQPPAAPGAGRQPPTPSAARPEPPPPQVERPWLDCLWIVLALLVFFGDVGTDLWLALDYYRKGDYVYFGLTLFFVLVPSLLVQSLSFRWFVQDYTGGGLGAVEGLTSRGPPMMGAGYVHGAARGGPGVRVSPTPGAQRLCRLSVWIWQSVIHLLQMGQVWRYIRTMYLGIQSQRRKEHQRRFYWAMMYEYADVNMLRLLETFLESAPQLVLQLYIMLQKNSAETLPCVSSVTSLMSLAWVLASYHKLLRDSRDDKKSMSYRGAIIQVFWRLFTISSRVISFALFASIFQLYFGIFVVVHWCAMAFWIIHGGTDFCMSKWEEILFNMVVGIVYIFCWFNVKEGRTRYRMFAYYTIVLTENAALTFLWYFYRDPETTDSYAVPALCCVFISFVAGIAMMLLYYGVLHPTGPRAKILASSCCAELLWGIPLPPDVEPMAPEIPGYRGTQVTPTRAVTEQQEDLTADTCLPVFQVRPMGPPTPLGRPYLPEGPLIKIDMPRKRYPAWDAHFVDRRLRRTINILQYVTPTAVGIRYRDGPLLYELLQYESSL", "length": 641 }, "evidence": [ { "id": "A0A8V0YA18", "url": "https://omabrowser.org/oma/group/A0A8V0YA18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "engulfment of apoptotic cell", "id": "GO:0043652", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043652", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18" } ], "pmid": "" }, { "name": "phosphatidylserine exposure on apoptotic cell surface", "id": "GO:0070782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18" } ], "pmid": "" }, { "name": "apoptotic process involved in development", "id": "GO:1902742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 213 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA24-1", "uniprot_ac": "A0A8V0YA24", "uniprot_id": "A0A8V0YA24_CHICK", "mass": { "chemical_mass": 8530.0, "monoisotopic_mass": 8530.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YA24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA24/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA24", "locus": {} } ], "crossref": [ { "id": "A0A8V0YA24", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YA24", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YA24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNAQKRQHGDGISGSLKAVNDCICYYQALVGDVL", "length": 74, "header": "tr|A0A8V0YA24-1|A0A8V0YA24_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YA24-1" }, "isoforms": [ { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA39-1", "uniprot_ac": "A0A8V0YA39", "uniprot_id": "A0A8V0YA39_CHICK", "mass": { "chemical_mass": 65423.0, "monoisotopic_mass": 65423.0 }, "refseq": { "ac": "NP_001384126", "name": "vesicular glutamate transporter 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126" }, "gene_names": [ { "name": "SLC17A8", "type": "recommended", "evidence": [ { "id": "A0A8V0YA39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ] }, { "name": "SLC17A8", "type": "synonym", "evidence": [ { "id": "NP_001384126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126" } ] }, { "name": "VGLUT3", "type": "synonym", "evidence": [ { "id": "NP_001384126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126" } ] } ], "protein_names": [ { "name": "Solute carrier family 17 member 8", "type": "synonym", "evidence": [ { "id": "A0A8V0YA39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8", "type": "synonym", "evidence": [ { "id": "NP_001384126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126" } ] }, { "name": "solute carrier family 17 (vesicular glutamate transporter), member 8", "type": "synonym", "evidence": [ { "id": "NP_001384126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126" } ] }, { "name": "vesicular glutamate transporter 3", "type": "synonym", "evidence": [ { "id": "NP_001384126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: KM272945.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA3109051 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384126", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC17A8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39", "locus": { "chromosome": "1", "start_pos": 47366463, "end_pos": 47338847, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011553", "url": "https://www.ensembl.org/id/ENSGALG00010011553" } ] } } ], "crossref": [ { "id": "A0A8V0YA39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YA39", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17382", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17382", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427877", "url": "https://www.ncbi.nlm.nih.gov/gene/427877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VTTIFWN", "url": "https://omabrowser.org/oma/group/VTTIFWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA39", "url": "https://www.orthodb.org/?gene=A0A8V0YA39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIG9", "url": "https://www.orthodb.org/?gene=A0A8V0YIG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIH2", "url": "https://www.orthodb.org/?gene=A0A8V0YIH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662:SF207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662:SF207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-442660", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001384126", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "66336", "url": "https://www.rhea-db.org/rhea/66336", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71255", "url": "https://www.rhea-db.org/rhea/71255", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFKGFHSLKERFFNPGKEEVKNTVSDSLGNLRRKIDGTNIEEDHIELTEEGRPVQASARKPQVCDCYCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYINGKPELQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFIANKLAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWSSVFYIYGMFGIVWYMFWLLHAYESPAAHPTITREERVYIETSIGEGASLASTNKFSTPWKRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIIVPIGGQIADFLRSRKILTTTTVRKVMNCGGFGMEATLLLVVGYSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYAIFASGEKQEWADPENLNEEKCGIIDQDELAEETEMNNETFVTPKKTYGATSQNSEIQRREWRKQKQMTQDMEEQTSYHYENGNFQDLS", "length": 587, "header": "tr|A0A8V0YA39-1|A0A8V0YA39_CHICK Isoform 1 of Solute carrier family 17 member 8 OS=Gallus gallus OX=9031 GN=SLC17A8 PE=3 SV=1 CANONICAL=A0A8V0YA39-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39/entry#A0A8V0YA39-1", "sequence": { "sequence": "MPFKGFHSLKERFFNPGKEEVKNTVSDSLGNLRRKIDGTNIEEDHIELTEEGRPVQASARKPQVCDCYCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYINGKPELQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFIANKLAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWSSVFYIYGMFGIVWYMFWLLHAYESPAAHPTITREERVYIETSIGEGASLASTNKFSTPWKRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIIVPIGGQIADFLRSRKILTTTTVRKVMNCGGFGMEATLLLVVGYSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYAIFASGEKQEWADPENLNEEKCGIIDQDELAEETEMNNETFVTPKKTYGATSQNSEIQRREWRKQKQMTQDMEEQTSYHYENGNFQDLS", "length": 587, "header": "tr|A0A8V0YA39-1|A0A8V0YA39_CHICK Isoform 1 of Solute carrier family 17 member 8 OS=Gallus gallus OX=9031 GN=SLC17A8 PE=3 SV=1 CANONICAL=A0A8V0YA39-1" }, "locus": { "chromosome": "1", "start_pos": 47364743, "end_pos": 47339115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027652.1", "url": "https://www.ensembl.org/id/ENSGALT00010027652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015845.1", "url": "https://www.ensembl.org/id/ENSGALP00010015845.1" } ] } }, { "isoform_ac": "A0A8V0YIG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39/entry#A0A8V0YIG9-1", "sequence": { "sequence": "MAAEGQSDRMTSDVEEWMKQRKIDGTNIEEDHIELTEEGRPVQASARKPQVCDCYCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYINGKPELQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFIANKLAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWSSVFYIYGMFGIVWYMFWLLHAYESPAAHPTITREERVYIETSIGEGASLASTNKFSTPWKRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIIVPIGGQIADFLRSRKILTTTTVRKVMNCGGFGMEATLLLVVGYSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYAIFASGEKQEWADPENLNEEKCGIIDQDELAEETEMNNETFVTPKKTYGATSQNSEIQRREWRKQKQMTQDMEEQTSYHYENGNFQDLS", "length": 574, "header": "tr|A0A8V0YIG9-1|A0A8V0YA39_CHICK Computationally mapped isoform of Solute carrier family 17 member 8 OS=Gallus gallus OX=9031 GN=SLC17A8 PE=3 SV=1 CANONICAL=A0A8V0YA39-1" }, "locus": { "chromosome": "1", "start_pos": 47364743, "end_pos": 47342680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027643.1", "url": "https://www.ensembl.org/id/ENSGALT00010027643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015837.1", "url": "https://www.ensembl.org/id/ENSGALP00010015837.1" } ] } }, { "isoform_ac": "A0A8V0YIH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39/entry#A0A8V0YIH2-1", "sequence": { "sequence": "MPFKGFHSLKERFFNPGKEEVKNTVSDSLGNLRRKIDGTNIEEDHIELTEEGRPVQASARKPQVCDCYCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYINGKPELQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFIANKLAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWSSVFYIYGMFGIVWYMFWLLHAYESPAAHPTITREERVYIETSIGEGASLASTNVGLLSAVPHMVMTIIVPIGGQIADFLRSRKILTTTTVRKVMNCGGFGMEATLLLVVGYSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYAIFASGEKQEWADPENLNEEKCGIIDQDELAEETEMNNETFVTPKKTYGATSQNSEIQRREWRKQKQMTQDMEEQTSYHYENGNFQDLS", "length": 537, "header": "tr|A0A8V0YIH2-1|A0A8V0YA39_CHICK Computationally mapped isoform of Solute carrier family 17 member 8 OS=Gallus gallus OX=9031 GN=SLC17A8 PE=3 SV=1 CANONICAL=A0A8V0YA39-1" }, "locus": { "chromosome": "1", "start_pos": 47364743, "end_pos": 47339115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027650.1", "url": "https://www.ensembl.org/id/ENSGALT00010027650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015842.1", "url": "https://www.ensembl.org/id/ENSGALP00010015842.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-442660", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-442660", "resource": "Reactome", "description": "SLC-mediated transport of neurotransmitters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZKV3-1", "protein_name": "Solute carrier family 17 member 8", "gene_name": "SLC17A8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELNEEGRPVQTSRQRPPLCDCHCCGVPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAASRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGVLVQYIGWASVFYIYGMLGMLWYMFWLLQAYECPSAHPTISHEEKTYIETSIGEGANLVSLSKFNTPWKRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQEWADPENLSEEKCGIIDRDELAEETELNHECFASPQKKMSYGATTQNCEVQRKEWRGQRRGTLDEEELTSYQNEEGTFSDTS", "length": 544 }, "evidence": [ { "id": "A0A8V0YA39", "url": "https://omabrowser.org/oma/group/A0A8V0YA39/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MTN4-1", "protein_name": "Vesicular glutamate transporter 3 isoform X1", "gene_name": "Slc17a8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPFKAFDTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTNEEEDNIELNEEGRPVQASRPHLPVCDCSCCGIPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQMAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFLTSTLNIFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFGIIWYIFWLLQAYECPAAHPTISNAEKTYIETSIGEGANLASPSKFNTPWKRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADCLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPESLSEEKCGIIDQDELAEETELNHEAILSPRKKMSYGATTQNVKVQKSGWRQQREAAFDEEEALSYQNEGDYSETS", "length": 588 }, "evidence": [ { "id": "A0A8V0YA39", "url": "https://omabrowser.org/oma/group/A0A8V0YA39/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9T9G5-1", "protein_name": "Solute carrier family 17 member 8", "gene_name": "SLC17A8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFKAFNTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTNEEEVNIELNEEGRPVQTPRQKPPLCDCHCCGVPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFFTSTLNMFIPSAARAHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGVLVQYIGWASVFYTYGILGIIWYMFWLLQAYECPAAHPTISQEERTYIETSIGEGANLVSLSVGLLSAVPHMVMTIIVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGMAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGIFASGEKQEWADPENLSEEKCGIIDQDELAEETELNHESFASPRKMSYGATTQNCEVQRKEWRGQRGVTLNEEELTSYQNEGGNFSDAS", "length": 538 }, "evidence": [ { "id": "A0A8V0YA39", "url": "https://omabrowser.org/oma/group/A0A8V0YA39/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TSF2-1", "protein_name": "Vesicular glutamate transporter 3", "gene_name": "Slc17a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFNAFDTFKEKILKPGKEGVKNAVGDSLGILQRKLDGTNEEGDAIELSEEGRPVQTSRARAPVCDCSCCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFGIIWYMFWLLQAYECPAVHPTISNEERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSEEKCGIIDQDELAEETELNHEAFVSPRKKMSYGATTQNCEVQKTDRRQQRESAFEGEEPLSYQNEEDFSETS", "length": 588 }, "evidence": [ { "id": "A0A8V0YA39", "url": "https://omabrowser.org/oma/group/A0A8V0YA39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7XJR2-1", "protein_name": "Probable anion transporter 3, chloroplastic", "gene_name": "ANTR3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATVGSLKPLHHSSCSSSFPRNPIVNRKALLGFVFDSARKNQIRCENLRYSSESDGKRRNAAAKKRNQSPERCAAEGVLTGGGGSEAIAEVRTMMPERIKVVILTACMMCLCNADRVVMSVAVVPLADKLGWSSSFLGVVQSSFLWGYIFSSVIGGALVDRYGGKRVLAWGVALWSLATLLTPWAAAHSTLALLCVRAFFGLAEGVAMPSMTTLLSRWFPMDERASAVGISMAGFHMGNVVGLLLTPLMLSSIGISGPFILFASLGLLWVSTWSSGVTNNPQDSPFITRSELRLIQAGKPVQPSTISPKPNPSLRLLLSKLPTWAIIFANVTNNWGYFVLLSWMPVYFQTVFNVNLKQAAWFSALPWATMAISGYYAGAASDFLIRTGHSVTSVRKIMQSIGFMGPGLSLLCLNFAKSPSCAAVFMTIALSLSSFSQAGFLLNMQDIAPQYAGFLHGISNCAGTLAAIVSTIGTGYFVQWLGSFQAFLTVTAFLYFATTVFWLLFATGERVF", "length": 512 }, "evidence": [ { "id": "A0A8V0YA39", "url": "https://omabrowser.org/oma/group/A0A8V0YA39/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8BFU8-1", "protein_name": "Vesicular glutamate transporter 3", "gene_name": "Slc17a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFKAFDTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTNEEEDAIELNEEGRPVQTSRAHRPVCDCSCCGIPKRYICDCSCCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAASRVFGAAIFLTSTLNMFIPSAARVHYGCVMGVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNAERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSEDKCGIIDQDELAEETELNHETFVSPRKKMSYGATTQNCEVQKTEWRQQRESAFDGEEPLSYQAEGDFSETS", "length": 601 }, "evidence": [ { "id": "A0A8V0YA39", "url": "https://omabrowser.org/oma/group/A0A8V0YA39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NDX2-1", "protein_name": "Vesicular glutamate transporter 3", "gene_name": "SLC17A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFKAFDTFKEKILKPGKEGVKNAVGDSLGILQRKIDGTTEEEDNIELNEEGRPVQTSRPSPPLCDCHCCGLPKRYIIAIMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWGYIMTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWSSVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNEEKTYIETSIGEGANVVSLSKFSTPWKRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRQILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTRHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQEWADPENLSEEKCGIIDQDELAEEIELNHESFASPKKKMSYGATSQNCEVQKKEWKGQRGATLDEEELTSYQNEERNFSTIS", "length": 589 }, "evidence": [ { "id": "A0A8V0YA39", "url": "https://omabrowser.org/oma/group/A0A8V0YA39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "neurotransmitter transmembrane transporter activity", "id": "GO:0005326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "sodium:phosphate symporter activity", "id": "GO:0005436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "L-glutamate uniporter activity", "id": "GO:0140788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140788", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "excitatory synapse", "id": "GO:0060076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "regulation of synapse structure or activity", "id": "GO:0050803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "phosphate ion homeostasis", "id": "GO:0055062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "phosphate ion transport", "id": "GO:0006817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "neurotransmitter loading into synaptic vesicle", "id": "GO:0098700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "positive regulation of glutamate uptake involved in transmission of nerve impulse", "id": "GO:0051951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051951", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "regulation of acetylcholine uptake", "id": "GO:0051631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" }, { "name": "neurotransmitter transport", "id": "GO:0006836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006836", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9Y7-1" ], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] }, { "id": "66336", "name": "", "equation": "L-glutamate(out) = L-glutamate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "66336", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66336" } ] }, { "id": "71255", "name": "", "equation": "3 Na(+)(out) + phosphate(out) = 3 Na(+)(in) + phosphate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71255", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71255" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA41-1", "uniprot_ac": "A0A8V0YA41", "uniprot_id": "A0A8V0YA41_CHICK", "mass": { "chemical_mass": 38563.0, "monoisotopic_mass": 38563.0 }, "refseq": {}, "gene_names": [ { "name": "RPP40", "type": "recommended", "evidence": [ { "id": "A0A8V0YA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41" } ] } ], "protein_names": [ { "name": "Ribonuclease P/MRP subunit p40", "type": "synonym", "evidence": [ { "id": "A0A8V0YA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41", "locus": {} } ], "crossref": [ { "id": "cd01650", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01650", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA41", "url": "https://www.orthodb.org/?gene=A0A8V0YA41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YA41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQLKVKQGIRPSQHGFTNGRSCLTNLIQFYDKVTHLVDDGKAVDVVYLDFSKAFDTVPHNILVEKLAAHGLDGRMLCWVKHWLDGRAQRVVVNGVESSWWPVTSSGPQGSVLGPLLFNIFINDLDEGIDCTLSKFADDTKLGGSVDLPEGRRALQRDLNRLDQWAKINSMSFNRAKYWVLHFGHNPRQPYRLGDEWLESFLMERDLGVLMDSCPNMSQQCAQVAKKANGILACMRNDVVSRTGEVTLPLYSALVRPHLEYCIQIWAPQYRKDIEVLEQVQRRATRLVNGLENMPYEEGLKELGQFSLGKRRLRADLIALFQYLSGVYSMSGVGLFSLVTG", "length": 341, "header": "tr|A0A8V0YA41-1|A0A8V0YA41_CHICK Isoform 1 of Ribonuclease P/MRP subunit p40 OS=Gallus gallus OX=9031 GN=RPP40 PE=4 SV=1 CANONICAL=A0A8V0YA41-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41/entry#A0A8V0YA41-1", "sequence": { "sequence": "MDQLKVKQGIRPSQHGFTNGRSCLTNLIQFYDKVTHLVDDGKAVDVVYLDFSKAFDTVPHNILVEKLAAHGLDGRMLCWVKHWLDGRAQRVVVNGVESSWWPVTSSGPQGSVLGPLLFNIFINDLDEGIDCTLSKFADDTKLGGSVDLPEGRRALQRDLNRLDQWAKINSMSFNRAKYWVLHFGHNPRQPYRLGDEWLESFLMERDLGVLMDSCPNMSQQCAQVAKKANGILACMRNDVVSRTGEVTLPLYSALVRPHLEYCIQIWAPQYRKDIEVLEQVQRRATRLVNGLENMPYEEGLKELGQFSLGKRRLRADLIALFQYLSGVYSMSGVGLFSLVTG", "length": 341, "header": "tr|A0A8V0YA41-1|A0A8V0YA41_CHICK Isoform 1 of Ribonuclease P/MRP subunit p40 OS=Gallus gallus OX=9031 GN=RPP40 PE=4 SV=1 CANONICAL=A0A8V0YA41-1" }, "locus": { "chromosome": "2", "start_pos": 65332694, "end_pos": 65322930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026834.1", "url": "https://www.ensembl.org/id/ENSGALT00010026834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015291.1", "url": "https://www.ensembl.org/id/ENSGALP00010015291.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YA41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA41" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 202, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA42-1", "uniprot_ac": "A0A8V0YA42", "uniprot_id": "A0A8V0YA42_CHICK", "mass": { "chemical_mass": 79587.0, "monoisotopic_mass": 79587.0 }, "refseq": { "ac": "XP_025000933", "name": "sodium/myo-inositol cotransporter", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000933" }, "gene_names": [ { "name": "SLC5A3", "type": "recommended", "evidence": [ { "id": "A0A8V0YA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ] }, { "name": "SLC5A3", "type": "synonym", "evidence": [ { "id": "XP_025000933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000933" } ] } ], "protein_names": [ { "name": "Sodium/myo-inositol cotransporter", "type": "recommended", "evidence": [ { "id": "A0A8V0YA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42/entry#names_and_taxonomy" } ] }, { "name": "Sodium/myo-inositol transporter 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 5 member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0YA42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42/entry#names_and_taxonomy" } ] }, { "name": "sodium/myo-inositol cotransporter", "type": "synonym", "evidence": [ { "id": "XP_025000933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000933" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025000933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000933" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC5A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42", "locus": {} } ], "crossref": [ { "id": "cd11491", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11491", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112530700", "url": "https://www.ncbi.nlm.nih.gov/gene/112530700", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:112530700", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112530700", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VGIFMFV", "url": "https://omabrowser.org/oma/group/VGIFMFV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA42", "url": "https://www.orthodb.org/?gene=A0A8V0YA42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11819", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11819", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11819:SF150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11819:SF150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-429593", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429593", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025000933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000933", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRASLETADIAIVALYFVLVMCIGFFAMWKYNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALMLLQLLGWVFVPVYIRSGVYTMPEYLSKRFGGHRIQIYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYLSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEVGGFEEVKRRYMLASPNITSILLTYNISNTNSCNVDPKPDALKMLREPADEDIPWPGFLLGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFADDIACINPEHCFQVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSATSRELMIVGRVFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLMGIFWKRCNEQGAFYGGMAGFILGAIRLILAFIYRAPECNQPDTRPSFIKSIHYMYVATALFWITGIVTFIVSLLTPPPTKEQVRTTTFWAVRNRNVKENTAKGERYKIQEKNILRCNENANHIIPNGKSEENIKNIKPEDINLLVTCRDDSNPVISVSHSEVETPVDCYSNGQAALMGEKKHEEETDDRERHLKFIDWFCGFKSKNMNKRAVREMEEETVCLQMLEETPKVKLLLNTGLVCVCSLGIFMFVYFSL", "length": 713, "header": "tr|A0A8V0YA42-1|A0A8V0YA42_CHICK Isoform 1 of Sodium/myo-inositol cotransporter OS=Gallus gallus OX=9031 GN=SLC5A3 PE=1 SV=1 CANONICAL=A0A8V0YA42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42/entry#A0A8V0YA42-1", "sequence": { "sequence": "MRASLETADIAIVALYFVLVMCIGFFAMWKYNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALMLLQLLGWVFVPVYIRSGVYTMPEYLSKRFGGHRIQIYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYLSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEVGGFEEVKRRYMLASPNITSILLTYNISNTNSCNVDPKPDALKMLREPADEDIPWPGFLLGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFADDIACINPEHCFQVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSATSRELMIVGRVFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLMGIFWKRCNEQGAFYGGMAGFILGAIRLILAFIYRAPECNQPDTRPSFIKSIHYMYVATALFWITGIVTFIVSLLTPPPTKEQVRTTTFWAVRNRNVKENTAKGERYKIQEKNILRCNENANHIIPNGKSEENIKNIKPEDINLLVTCRDDSNPVISVSHSEVETPVDCYSNGQAALMGEKKHEEETDDRERHLKFIDWFCGFKSKNMNKRAVREMEEETVCLQMLEETPKVKLLLNTGLVCVCSLGIFMFVYFSL", "length": 713, "header": "tr|A0A8V0YA42-1|A0A8V0YA42_CHICK Isoform 1 of Sodium/myo-inositol cotransporter OS=Gallus gallus OX=9031 GN=SLC5A3 PE=1 SV=1 CANONICAL=A0A8V0YA42-1" }, "locus": { "chromosome": "1", "start_pos": 105806526, "end_pos": 105806453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030330.1", "url": "https://www.ensembl.org/id/ENSGALT00010030330.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017593.1", "url": "https://www.ensembl.org/id/ENSGALP00010017593.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:112530700", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112530700", "resource": "KEGG Pathway" }, { "id": "R-GGA-429593", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429593", "resource": "Reactome", "description": "Inositol transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A6C9-1", "protein_name": "Sodium/myo-inositol cotransporter", "gene_name": "SLC5A3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAVLETADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIVGALTLMIISMMEIGGFEEVKRRYMLASPNVTSILLTYNLSNTNSCNVHPKKDALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFADDIACINPEHCMQVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFILGAVRLTLAFAYRAPECDQPDERPGFIKDIHYMYVATALFWVTGLITVIVSLLTPPPTKEQIRTTTFWSKKSLVVKESCSPKDEPYKMQEKSILRCSENSEAINQIIPNGKSEDSIKGIQPEDVNLLVTCKEEGNPVSSLGHSEAETPVDAYSNGQAALMGEKERKKETEDGSRYWKFIDWFCGFKSKSLSKRSLRDLMEEEAVCLQMLEEPPQVKIILNIGLFAVCSLGIFMFVYFSL", "length": 718 }, "evidence": [ { "id": "A0A8V0YA42", "url": "https://omabrowser.org/oma/group/A0A8V0YA42/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GM79-1", "protein_name": "Sodium/myo-inositol cotransporter", "gene_name": "Slc5a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAVLETADIAIVALYFVLVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMMKVGGFEEVKRRYMLASPNVASILLTHNLSNTNSCMVHPKADALKMLRDPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFVDDIACINPEHCMQVCGSRAGCSNIAYPRLVMELVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLLRNNASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAIRLILAFTYRAPECDQPDNRPSFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTVVTKESCSQKDEPYKMQEKSILRCSENSEVVSHTIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASMGHSEAETPVDAYSNGQAALMGERAREKETESRSRYWKFIDWFCGFKSRSLSKRSLRDSMDEEAVCLQMLEETPRVRVILNIGLFAVCSLGIFMFVYFSL", "length": 718 }, "evidence": [ { "id": "A0A8V0YA42", "url": "https://omabrowser.org/oma/group/A0A8V0YA42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GT66-1", "protein_name": "Sodium/myo-inositol cotransporter", "gene_name": "Slc5a3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRAVLETADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMMEVGGFEEVKKRYMLASPNVASILLTHNLSNTNSCNVHPKDDALKMLRDPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFVDDIACINPEHCMQVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVVSIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFTYRAPECDQPDNRPGFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTLVTKESCSQKDEPYRMQEKSILRCSDNSEVVNHVIPNGKSEDSIKGLQPEDVNLLVACREEGNPVASLGHSEAETPVDAYSNGQAALMGEKEREKETENRSRYWEFVDWFCGFKSKSLSKRSLRDLMDEEAVCSQMLEESPQVKVVLNIGLFAVCSLGIFMFVYFSL", "length": 718 }, "evidence": [ { "id": "A0A8V0YA42", "url": "https://omabrowser.org/oma/group/A0A8V0YA42/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P53794-1", "protein_name": "Sodium/myo-inositol cotransporter", "gene_name": "SLC5A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVIVSLLTPPPTKEQIRTTTFWSKKNLVVKENCSPKEEPYKMQEKSILRCSENNETINHIIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASLGHSEAETPVDAYSNGQAALMGEKERKKETDDGGRYWKFIDWFCGFKSKSLSKRSLRDLMEEEAVCLQMLEETRQVKVILNIGLFAVCSLGIFMFVYFSL", "length": 718 }, "evidence": [ { "id": "A0A8V0YA42", "url": "https://omabrowser.org/oma/group/A0A8V0YA42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKZ2-1", "protein_name": "Sodium/myo-inositol cotransporter", "gene_name": "Slc5a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAVLEAADIAVVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLLLYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMVISMVKIGGFEEVKRRYMLASPDVASILLKYNLSNTNACMVHPKANALKMLRDPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGFLKLLPMFIIVVPGMISRIVFADEIACINPEHCMQVCGSRAGCSNIAYPRLVMTLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILAFTYRAPECDQPDNRPGFIKDIHYMYVATALFWITGLITVIVSLLTPPPTKDQIRTTTFWSKKTLVTKESCSQKDEPYKMQEKSILQCSENSEVISHTIPNGKSEDSIKGLQPEDVNLLVTCREEGNPVASMGHSEAETPVDAYSNGQAALMGEREREKETENRSRYWKFIDWFCGFKSKSLSKRSLRDLMDEEAVCLQMLEETPQVKVILNIGLFAVCSLGIFMFVYFSL", "length": 718 }, "evidence": [ { "id": "A0A8V0YA42", "url": "https://omabrowser.org/oma/group/A0A8V0YA42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "myo-inositol:sodium symporter activity", "id": "GO:0005367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005367", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ], "pmid": "" }, { "name": "D-glucose:sodium symporter activity", "id": "GO:0005412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA49-1", "uniprot_ac": "A0A8V0YA49", "uniprot_id": "A0A8V0YA49_CHICK", "mass": { "chemical_mass": 106424.0, "monoisotopic_mass": 106424.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Synaptonemal complex protein 2 like", "type": "synonym", "evidence": [ { "id": "A0A8V0YA49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49", "locus": {} } ], "crossref": [ { "id": "A0A8V0YA49", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YA49", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR024835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15607:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15607:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18584", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18584", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YA49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YER5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YER5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YER5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAHAEDYLESLLIDAFKGKGYQKISDLLQEKETDTLQKYSNSLLSQLDKALRRELDRNDFHNVSLLLKCIQLYFKSDLQQGTSLFVEQGLVEKMTRMFVILIDPTENSFLMVLLEDFFDSALVCAWKKQLVNLFLPELGRLVTEAGICCALRQEALRTLNSILDSIPREGRKKLPLSEEVCFLTKDLAKTMLEAGDYDLQVALSEALCRLTIKKWRDDLVNHWFEDKYLAEAFKEIKDKEFETDCRKFLNQLNERLGDKRRVYSFPCLSAFADVNQVKKPSDEKLDKFWIDFNAGSHSVTFYIDSIEGVLWDSVRLQKEAVSCYSLKEDGGEKIVKIYMKIPATLNKTEATKIKLHFSAEYEILSILKKVLGDEKMMTNVGEEESIHTEKQTRQNEVTSQSNDLQKRKDPENSENMDPIPENLILQHNEQLVGTVPKTSNSDVTMTAVNQQSGLDEADQSSVKAGKQKHLLVAPEGEAVVSLSPSANKSKTLSPRMNAKSSEKPQEEKLMEASTPKKVGTVERRTRIKGLVKQKTEGRKDTYDFEVSDSASHEKVKGKGRWLNRTPNGIFHLSYRKHLFSESNNEKTSNSESEKSWILESQKETLPKSLNYTRKRRRVRRKLKVLPVSSPSSSNENRMEKGAAGQKNEKKASRKKSTSISKGDDLPTVDLAGEVPSEEPKGTWQPLDVSMEEHSGVEEEATQKFHDVSEETREESFKRKDLEALSGTVVKKPRFFNWETKHLSSESPFKPNKLSNSVEKEEEIKRGQETVDVNTAFLSKIQHEDIGDSGVIAVFESFTNQLKQLFWSRYKEMEMSAQNMLRTSEKNVSALLKEIHKCRLNKLETFKKIVMEELASLEKDTQILRNMEKDAVDFWDAQLQKLNSFCNQQKQRIQSVDSALGETAESFASTIVNTPHNVSMKSAVENGVFVVPSD", "length": 934, "header": "tr|A0A8V0YA49-1|A0A8V0YA49_CHICK Isoform 1 of Synaptonemal complex protein 2 like OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YA49-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49/entry#A0A8V0YA49-1", "sequence": { "sequence": "MAAHAEDYLESLLIDAFKGKGYQKISDLLQEKETDTLQKYSNSLLSQLDKALRRELDRNDFHNVSLLLKCIQLYFKSDLQQGTSLFVEQGLVEKMTRMFVILIDPTENSFLMVLLEDFFDSALVCAWKKQLVNLFLPELGRLVTEAGICCALRQEALRTLNSILDSIPREGRKKLPLSEEVCFLTKDLAKTMLEAGDYDLQVALSEALCRLTIKKWRDDLVNHWFEDKYLAEAFKEIKDKEFETDCRKFLNQLNERLGDKRRVYSFPCLSAFADVNQVKKPSDEKLDKFWIDFNAGSHSVTFYIDSIEGVLWDSVRLQKEAVSCYSLKEDGGEKIVKIYMKIPATLNKTEATKIKLHFSAEYEILSILKKVLGDEKMMTNVGEEESIHTEKQTRQNEVTSQSNDLQKRKDPENSENMDPIPENLILQHNEQLVGTVPKTSNSDVTMTAVNQQSGLDEADQSSVKAGKQKHLLVAPEGEAVVSLSPSANKSKTLSPRMNAKSSEKPQEEKLMEASTPKKVGTVERRTRIKGLVKQKTEGRKDTYDFEVSDSASHEKVKGKGRWLNRTPNGIFHLSYRKHLFSESNNEKTSNSESEKSWILESQKETLPKSLNYTRKRRRVRRKLKVLPVSSPSSSNENRMEKGAAGQKNEKKASRKKSTSISKGDDLPTVDLAGEVPSEEPKGTWQPLDVSMEEHSGVEEEATQKFHDVSEETREESFKRKDLEALSGTVVKKPRFFNWETKHLSSESPFKPNKLSNSVEKEEEIKRGQETVDVNTAFLSKIQHEDIGDSGVIAVFESFTNQLKQLFWSRYKEMEMSAQNMLRTSEKNVSALLKEIHKCRLNKLETFKKIVMEELASLEKDTQILRNMEKDAVDFWDAQLQKLNSFCNQQKQRIQSVDSALGETAESFASTIVNTPHNVSMKSAVENGVFVVPSD", "length": 934, "header": "tr|A0A8V0YA49-1|A0A8V0YA49_CHICK Isoform 1 of Synaptonemal complex protein 2 like OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YA49-1" }, "locus": { "chromosome": "2", "start_pos": 62943285, "end_pos": 62922057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025703.1", "url": "https://www.ensembl.org/id/ENSGALT00010025703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014486.1", "url": "https://www.ensembl.org/id/ENSGALP00010014486.1" } ] } }, { "isoform_ac": "A0A8V0YER5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49/entry#A0A8V0YER5-1", "sequence": { "sequence": "MFVILIDPTENSFLMVLLEDFFDSALVICKCSNEGKKQLVNLFLPELGRLVTEAGICCALRQEALRTLNSILDSIPREGRKKLPLSEEVCFLTKDLAKTMLEAGDYDLQVALSEALCRLTIKKWRDDLVNHWFEDKYLAEAFKEIKDKEFETDCRKFLNQLNERLGDKRRVYSFPCLSAFADVNQVKKPSDEKLDKFWIDFNAGSHSVTFYIDSIEGVLWDSVRLQKEAVSCYSLKEDGGEKIVKIYMKIPATLNKTEATKIKLHFSAEYEILSILKKVLGDEKMMTNVGEEESIHTEKQTRQNEVTSQSNDLQKRKDPENSENMDPIPENLILQHNEQLVGTVPVSVWRMKTSNSDVTMTAVNQQSGLDEADQSSVKAGKQKHLLVAPEGEAVVSLSPSANKSKTLSPRMNAKSSEKPQEEKLMEASTPKKVGTVERRTRIKGLVKQKTEGRKDTYDFEVSDSASHEKVAEAKGKVFGKKNSLQNQSYRKHLFSESNNEKTSNSESEKSWILESQKETLPKSLNYTRKRRRVRRKLKVLPVSSPSSSNENRMEKQGAAGQKNEKKASRKKSTSISKGDDLPTVDLAGEVPSEEPKGTWQPLDVSMEEHSGVEEEATQKFHDVSEETREESFKRKDLEALSGTVVKKPRFFNWETKHLSSESPFKPNKLSNSVEKEEEIKRGQETVDVNTAFLSKIQHEDIGDSGVIAVFESFTNQLKQLFWSRYKEMEMSAQNMLRTSEKNVSALLKEIHKCRLNKLETFKKIVMEELASLEKDTQILRNMEKDAVDFWDAQLQKLNSFCNQQKQRIQSVDSALGETAESFASTIVNTPHNVSMKSAVENGVFVVPSD", "length": 849, "header": "tr|A0A8V0YER5-1|A0A8V0YA49_CHICK Computationally mapped isoform of Synaptonemal complex protein 2 like OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0YA49-1" }, "locus": { "chromosome": "2", "start_pos": 62941402, "end_pos": 62922057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025681.1", "url": "https://www.ensembl.org/id/ENSGALT00010025681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014473.1", "url": "https://www.ensembl.org/id/ENSGALP00010014473.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" } ], "pmid": "" }, { "name": "condensed chromosome, centromeric region", "id": "GO:0000779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" } ], "pmid": "" }, { "name": "lateral element", "id": "GO:0000800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000800", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" }, { "start_pos": 917, "end_pos": 919, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YA49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" }, { "id": "PF18584", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18584" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synaptonemal complex protein 2 Spt16M-like", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 373, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YA49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA49" }, { "id": "PF18581", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18581" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synaptonemal complex protein 2 armadillo-repeat-like", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 170, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 347, "end_pos": 349 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 827, "end_pos": 829 }, { "start_pos": 917, "end_pos": 919 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YA58-1", "uniprot_ac": "A0A8V0YA58", "uniprot_id": "A0A8V0YA58_CHICK", "mass": { "chemical_mass": 66196.0, "monoisotopic_mass": 66196.0 }, "refseq": { "ac": "XP_004937179", "name": "protein FAM214B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937179" }, "gene_names": [ { "name": "FAM214B", "type": "recommended", "evidence": [ { "id": "A0A8V0YA58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58" } ] }, { "name": "FAM214B", "type": "synonym", "evidence": [ { "id": "XP_004937179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937179" } ] } ], "protein_names": [ { "name": "Atos homolog protein B", "type": "recommended", "evidence": [ { "id": "A0A8V0YA58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58/entry#names_and_taxonomy" } ] }, { "name": "protein FAM214B", "type": "synonym", "evidence": [ { "id": "XP_004937179", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937179" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937179.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937179", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937179" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM214B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58", "locus": {} } ], "crossref": [ { "id": "A0A8V0YA58", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YA58", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858763", "url": "https://www.ncbi.nlm.nih.gov/gene/100858763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858763", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858763", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGHSHER", "url": "https://omabrowser.org/oma/group/NGHSHER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA58", "url": "https://www.orthodb.org/?gene=A0A8V0YA58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA63", "url": "https://www.orthodb.org/?gene=A0A8V0YA63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIJ6", "url": "https://www.orthodb.org/?gene=A0A8V0YIJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13199:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13199:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937179", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937179", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHIHTETSLPPERSPDSSLSRPSGEAALEPSSQHCAHHSILMGYNETEIKRQKVYQVSIFSHLSSSSESTEQRAGSHPTLKRSYPEQRTPEGVRDPKRTHWGGGVDSKRDGGLGQSALEDDDTFEDGLLVDELSLCGSAQHFSHSGLQVVEHRCVSSPSPKANREDKLQDTSSFWPQHIACSTLHTRDSCPVPPGNQLADCWDNGERMSGHNLLDLDLHNIAQKPQLDCGGRGEKPGSSPAHSSGAGEAEEWPVVANGCKEPLAPQMLLSPEPSNLNSQEKTPCGNSSSSSSGSSSSCPAKRKLLPAGEMADSCSEDESLSQLVRKKRALPCHPVPTACRSTDAKGAPFWNHLLPTAKSSADCTTVGRRLKSGLRLKSRHLRSSLRRGTRSSAASWATTTVSHALLGNFEESILKGRFAPSGRIEGFTAEIGASGSYCPQHVTLPVDVTYFDISEHSVPSPFLGVIDLEALGKKGYSVPKAGTIQVTLFNPNKTVVKMFLVTYDFQDMPANHMTFLRHRIFLVPVGKEKGVTVACSEPPGTGPPRRVLCYLMHLRFHSSKSGKIYLHDNIRLLFSRKSIEVDSGIPYELKSFTEMPRNPRYSPWP", "length": 606, "header": "tr|A0A8V0YA58-1|A0A8V0YA58_CHICK Isoform 1 of Atos homolog protein B OS=Gallus gallus OX=9031 GN=FAM214B PE=3 SV=1 CANONICAL=A0A8V0YA58-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58/entry#A0A8V0YA58-1", "sequence": { "sequence": "MRHIHTETSLPPERSPDSSLSRPSGEAALEPSSQHCAHHSILMGYNETEIKRQKVYQVSIFSHLSSSSESTEQRAGSHPTLKRSYPEQRTPEGVRDPKRTHWGGGVDSKRDGGLGQSALEDDDTFEDGLLVDELSLCGSAQHFSHSGLQVVEHRCVSSPSPKANREDKLQDTSSFWPQHIACSTLHTRDSCPVPPGNQLADCWDNGERMSGHNLLDLDLHNIAQKPQLDCGGRGEKPGSSPAHSSGAGEAEEWPVVANGCKEPLAPQMLLSPEPSNLNSQEKTPCGNSSSSSSGSSSSCPAKRKLLPAGEMADSCSEDESLSQLVRKKRALPCHPVPTACRSTDAKGAPFWNHLLPTAKSSADCTTVGRRLKSGLRLKSRHLRSSLRRGTRSSAASWATTTVSHALLGNFEESILKGRFAPSGRIEGFTAEIGASGSYCPQHVTLPVDVTYFDISEHSVPSPFLGVIDLEALGKKGYSVPKAGTIQVTLFNPNKTVVKMFLVTYDFQDMPANHMTFLRHRIFLVPVGKEKGVTVACSEPPGTGPPRRVLCYLMHLRFHSSKSGKIYLHDNIRLLFSRKSIEVDSGIPYELKSFTEMPRNPRYSPWP", "length": 606, "header": "tr|A0A8V0YA58-1|A0A8V0YA58_CHICK Isoform 1 of Atos homolog protein B OS=Gallus gallus OX=9031 GN=FAM214B PE=3 SV=1 CANONICAL=A0A8V0YA58-1" }, "locus": { "chromosome": "Z", "start_pos": 9148834, "end_pos": 9144250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027685.1", "url": "https://www.ensembl.org/id/ENSGALT00010027685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015865.1", "url": "https://www.ensembl.org/id/ENSGALP00010015865.1" } ] } }, { "isoform_ac": "A0A8V0YA63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58/entry#A0A8V0YA63-1", "sequence": { "sequence": "MRHIHTETSLPPERSPDSSLSRPSGEAALEPSSQHCAHHSILMGYNETEIKRQKVYQVSIFSHLSSSSESTEQRAGSHPTLKRSYPEQRTPEGVRDPKRTHWGGGVDSKRDGGLGQSALEDDDTFEDGLLVDELSLCGSAQHFSHSGLQVVEHRCVSSPSPKANREDKLQDTSSFWPQHIACSTLHTRDSCPVPPGNQLADCWDNGERMSGHNLLDLDLHNIAQKPQLDCGGRGEKPGSSPAHSSGAGEAEEWPVVANGCKEPLAPQMLLSPEPSNLNSQEKTPCGNSSSSSSGSSSSCPAKRKLLPAGEMADSCSEDESLSQLVRKKRALPCHPVPTACRSTDAKGAPFWNHLLPTAKVSVTAGAGRGCSGLFLLGM", "length": 378, "header": "tr|A0A8V0YA63-1|A0A8V0YA63_CHICK Computationally mapped isoform of Atos homolog B OS=Gallus gallus OX=9031 GN=FAM214B PE=4 SV=1 CANONICAL=A0A8V0YA58-1" }, "locus": { "chromosome": "Z", "start_pos": 9143564, "end_pos": 9142378, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027690.1", "url": "https://www.ensembl.org/id/ENSGALT00010027690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015870.1", "url": "https://www.ensembl.org/id/ENSGALP00010015870.1" } ] } }, { "isoform_ac": "A0A8V0YIJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58/entry#A0A8V0YIJ6-1", "sequence": { "sequence": "MRHIHTETSLPPERSPDSSLSRPSGEAALEPSSQHCAHHSILMGYNETEIKRQKVYQVSIFSHLSSSSESTEQRAGSHPTLKRSYPEQRTPEGVRDPKRTHWGGGVDSKRDGGLGQSALEDDDTFEDGLLVDELSLCGSAQHFSHSGLQVVEHRCVSSPSPKANREDKLQDTSSFWPQHIACSTLHTRDSCPVPPGNQLADCWDNGERMSGHNLLDLDLHNIAQKPQLDCGGRGEKPGSSPAHSSGAGEAEEWPVVANGCKEPLAPQMLLSPEPSNLNSQEKTPCGNSSSSSSGSSSSCPAKRKLLPAGEMADSCSEDESLSQLVRKKRALPCHPVPTACRSTDAKGAPFWNHLLPTAKSSADCTTVGRRLKSGLRLKSRHLRSSLRRGTRSSAASWATTTVSHALLGNFEESILKGRFAPSGRIEGFTAEIGASGSYCPQHVTLPVDVTYFDISEHSVPSPFLTLFNPNKTVVKMFLVTYDFQDMPANHMTFLRHRIFLVPVGKEKGVTVACSEPPGTGPPRRVLCYLMHLRFHSSKSGKIYLHDNIRLLFSRKSIEVDSGIPYELKSFTEMPRNPRYSPWP", "length": 583, "header": "tr|A0A8V0YIJ6-1|A0A8V0YA58_CHICK Computationally mapped isoform of Atos homolog protein B OS=Gallus gallus OX=9031 GN=FAM214B PE=3 SV=1 CANONICAL=A0A8V0YA58-1" }, "locus": { "chromosome": "Z", "start_pos": 9148834, "end_pos": 9144250, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027687.1", "url": "https://www.ensembl.org/id/ENSGALT00010027687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015867.1", "url": "https://www.ensembl.org/id/ENSGALP00010015867.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858763", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8BR27-1", "protein_name": "Atos homolog protein B", "gene_name": "Atosb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRHVQAELSPSSEPEAGPSQPPVRQGTLQGGLLMGYSPAGGATSPGVYQVSIFSPSAGASEPPRALKRPAPPTEGPRELKRGPGLGAREGLPPEEPSTVGLLSPEGLGLGLGVASQHFSHHGLCVVEHGGNTTSPWTSGTQSTPWLSSNASFNTLHTRDWAFPDQGGQGCLGETPGPAPSGQLHTLDTDLHNLAQIGGKSPVARVGNGSNPWPRESHGTANGHSPEHTPPGPGPPGPCPTKRRLLPAGETLDVSSEDEGPAPRRRRGTLGCPLAANSSDAKATPFWSHLLPGPKEPVLDPTDCSPMGRRLKGARRLKLSSLRTLRKGPGLLSPPSASPFPTPAVSRTLLGNFEESLLRGRFAPSGHIEGFTAEIGASGSYCPQHVTLPVTVTFFDVSEQNAPAPFLGVVDLTPLGRKGYSVPKVGTIQVTLFNPNQTVVKMFLVTFDFSDMPAAHMTFLRHRLFLVPVGEEGNASPTHRLLCYLLHLRFRSSRSGRLSLHGDIRLLFSRRSLELDTGLPYELQAVTEAPHNPRYSPLP", "length": 538 }, "evidence": [ { "id": "A0A8V0YA58", "url": "https://omabrowser.org/oma/group/A0A8V0YA58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YA58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA58" }, { "id": "SM01177", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01177" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Atos-like conserved", "eco_id": "ECO_0000259", "start_pos": 406, "end_pos": 464, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], 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"length": 1028, "header": "tr|A0A8V0YA66-1|A0A8V0YA66_CHICK Computationally mapped isoform of Meiotic double-stranded break formation protein 1 OS=Gallus gallus OX=9031 GN=MEI1 PE=4 SV=1 CANONICAL=A0A8V0YA61-1" }, "locus": { "chromosome": "1", "start_pos": 49584993, "end_pos": 49555881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025727.1", "url": "https://www.ensembl.org/id/ENSGALT00010025727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014501.1", "url": "https://www.ensembl.org/id/ENSGALP00010014501.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-111446", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111446", "resource": "Reactome", "description": "Activation of BIM and translocation to mitochondria" }, { "id": "R-GGA-111453", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-111453", "resource": 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Isoform 1 of SKI family transcriptional corepressor 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YA64-1" }, "locus": { "chromosome": "Z", "start_pos": 2073464, "end_pos": 2056711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026894.1", "url": "https://www.ensembl.org/id/ENSGALT00010026894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015318.1", "url": "https://www.ensembl.org/id/ENSGALP00010015318.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 248, "start_aa": "Thr", "end_pos": 248, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr248", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": 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"MGADPGAAVPRFAVLSSHPWVSTAPLCAQRSSSCFTLKPSPAGREAPLSCSFLPEYTDASPFPLMSSGVEEVALGRPEDGAQPWQSMAEQQAVLSGGGQLRAACPEPGTQNLLQVLAASQHALSHVLTPKGPKDSSPCAREHEGSAAMDRLQNKAASSKGERSRGCGVAAGRSWRVPAARREKLSAGLAGTASPSQVAMASFAPRQQSGLTVLQRIQVCESREGAGSAAVGAFPSAAPTNSSDCDGVFLCKNCHQVFYTQKGLGSHMCFRDEQWLLPQRREEPQVKGKQRGRGAQKAKVGGRDGSGAVPNPSALPQSAVNLMEPLESFIQVTPKESQDGKSPQLSSHPKKRKRQILPKPLFIPPPPPPEAQPGPGGCYRSNLRSPVLLMDRLLRDLLQCSPYTPPPMLSPVREGSGLYFNAVCSSTAAEPCRLLGSVLDRMDQDFGLCLMKDGTKISIEPHINIGSRFQAEIPTLQDRPGLGSAEQAALVWKPWGDIATNEETQDRVMELLNMACSSVMPGGGTNLELALHCLHEARGNVVDALELLLFGWPHKSQSHPLANYRYTGSDVWTPVERQLFRNAFHAHKKDFYLIQKKVQTKNVSQCVEYYYIWKKIIKFDHSRAQNADKKAKRDGSEAEEAEEKPLCPPKKRHCLLPKESSKKSCRKAPHGAGSPSCSVGRAPGGVEHHNVFPCTECERVFDKIKGRNAHMKRHRPQHRAVPLLQAQWALGPLKREEAAAGGALSSSWGAEPPE", "length": 753, "header": "tr|A0A8V0YA99-1|A0A8V0YA99_CHICK Isoform 1 of Zinc finger protein 541 OS=Gallus gallus OX=9031 GN=ZNF541 PE=4 SV=1 CANONICAL=A0A8V0YA99-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99/entry#A0A8V0YA99-1", "sequence": { "sequence": "MGADPGAAVPRFAVLSSHPWVSTAPLCAQRSSSCFTLKPSPAGREAPLSCSFLPEYTDASPFPLMSSGVEEVALGRPEDGAQPWQSMAEQQAVLSGGGQLRAACPEPGTQNLLQVLAASQHALSHVLTPKGPKDSSPCAREHEGSAAMDRLQNKAASSKGERSRGCGVAAGRSWRVPAARREKLSAGLAGTASPSQVAMASFAPRQQSGLTVLQRIQVCESREGAGSAAVGAFPSAAPTNSSDCDGVFLCKNCHQVFYTQKGLGSHMCFRDEQWLLPQRREEPQVKGKQRGRGAQKAKVGGRDGSGAVPNPSALPQSAVNLMEPLESFIQVTPKESQDGKSPQLSSHPKKRKRQILPKPLFIPPPPPPEAQPGPGGCYRSNLRSPVLLMDRLLRDLLQCSPYTPPPMLSPVREGSGLYFNAVCSSTAAEPCRLLGSVLDRMDQDFGLCLMKDGTKISIEPHINIGSRFQAEIPTLQDRPGLGSAEQAALVWKPWGDIATNEETQDRVMELLNMACSSVMPGGGTNLELALHCLHEARGNVVDALELLLFGWPHKSQSHPLANYRYTGSDVWTPVERQLFRNAFHAHKKDFYLIQKKVQTKNVSQCVEYYYIWKKIIKFDHSRAQNADKKAKRDGSEAEEAEEKPLCPPKKRHCLLPKESSKKSCRKAPHGAGSPSCSVGRAPGGVEHHNVFPCTECERVFDKIKGRNAHMKRHRPQHRAVPLLQAQWALGPLKREEAAAGGALSSSWGAEPPE", "length": 753, "header": "tr|A0A8V0YA99-1|A0A8V0YA99_CHICK Isoform 1 of Zinc finger protein 541 OS=Gallus gallus OX=9031 GN=ZNF541 PE=4 SV=1 CANONICAL=A0A8V0YA99-1" }, "locus": { "chromosome": "38", "start_pos": 203547, "end_pos": 198336, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025806.1", "url": "https://www.ensembl.org/id/ENSGALT00010025806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014536.1", "url": "https://www.ensembl.org/id/ENSGALP00010014536.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YA99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 691, "end_pos": 718, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" }, { "id": "PS51156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELM2", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 551, "start_aa": "Pro", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YA99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA99" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 566, "end_pos": 617, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 }, { "start_pos": 601, "end_pos": 603 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAB4-1", "uniprot_ac": "A0A8V0YAB4", "uniprot_id": "A0A8V0YAB4_CHICK", "mass": { "chemical_mass": 106911.0, "monoisotopic_mass": 106911.0 }, "refseq": {}, "gene_names": [ { "name": "MAMLD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YAB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4" } ] } ], "protein_names": [ { "name": "Mastermind like domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YAB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAMLD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4", "locus": { "chromosome": "4", "start_pos": 17748028, "end_pos": 17824986, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011617", "url": "https://www.ensembl.org/id/ENSGALG00010011617" } ] } } ], "crossref": [ { "id": "A0A8V0YAB4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAB4", "url": "https://www.orthodb.org/?gene=A0A8V0YAB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBT7", "url": "https://www.orthodb.org/?gene=A0A8V0YBT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15275", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15275", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15275:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15275:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-2122947", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2122947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2197563", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2197563", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8941856", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8941856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YAB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLVSQRVEAPRMEPHIPLQGSIKRKLEDNSSPASSGVPDVIFPNDSKRLCLDDVTLSMGQGTHPNVVCPEMQSSPFSSSHSTSSMGVTGHSVLLENNRMNGSGIGSPFSVPPNTEINQKGSIGGQGNSIVHYDEKGNSLQSVDQELQDLLEELTKMPDPSPNDLDLEKILGSKAEEPLGLSHSQPSISTTPKSSPQTSHLENHVANKDFSPGCNPTSGGSPQMRPSSAGANFQVPPSSKPAASPISTAAQSKNQPPPMLSVPLPNIPASNWHAQQLKQLAASKQVSTTKQQVQAPSWPSMSPPGLSPPYRAGSSPHHQPFSPQNVMVSGMPTNNLPGNNIQSPQNTLLSSMTSSSTPSNGPSPPYGSEKLSSPALNQQPFSPQSSMLPALTAASLPASNIKSPQNNLVASMASTNTGPSPPYRPEKLSSPALHQQPFSPQGTLISNITPNNNPPSMQNSLFKSVTTSQSKNMNIIMQQSSASLQPGLVNESPVSQDQFSFSNTKPLSHFASESATQKMSPLTAGQGQQSLIHYLQQQQQQSPAAQQSQQANSSQLLQQQFRQLMQPHRMQRHMQSATLPSQNRQNPGLVARLQEPGSVPGGGSVPAPATVNGYAMRNHLLKQQIMKRQLMQEKQRQNMLGVTSEQRNLFASQQMNQFQAVQQPIPTDCSQPMPAPPPNHHMLPSNPAMLQSTLGTSITPVTANQSSGTMVMIPHNPGKQQTVFPPNSDFNIPLRPSQNSMAMNSGCQTVHSHAAVQPGMPMAGFSSGSLVNHSAAQQHLRQPSVPRIPSVYPNSSAQMWTPTAVPRMPNQSQMDTSMQQFSSNALFSKQNVRPNASGQQFSQQAVVPPNQIAPGVQVRQMQKLSMGQSGQGMSSMNNQNLRHSLTRGPLPAMNVMKSMPQGVSSFNQLNPPTGLGPPTYPAAGQPPDAFSRMSAAAELPQYDFVPQHSSSVLPTNCSDTDFLDSLMKSSSSNDEEWLNNLTMIDDILGQHAQSSGHV", "length": 998, "header": "tr|A0A8V0YAB4-1|A0A8V0YAB4_CHICK Isoform 1 of Mastermind like domain containing 1 OS=Gallus gallus OX=9031 GN=MAMLD1 PE=4 SV=1 CANONICAL=A0A8V0YAB4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4/entry#A0A8V0YAB4-1", "sequence": { "sequence": "MLLVSQRVEAPRMEPHIPLQGSIKRKLEDNSSPASSGVPDVIFPNDSKRLCLDDVTLSMGQGTHPNVVCPEMQSSPFSSSHSTSSMGVTGHSVLLENNRMNGSGIGSPFSVPPNTEINQKGSIGGQGNSIVHYDEKGNSLQSVDQELQDLLEELTKMPDPSPNDLDLEKILGSKAEEPLGLSHSQPSISTTPKSSPQTSHLENHVANKDFSPGCNPTSGGSPQMRPSSAGANFQVPPSSKPAASPISTAAQSKNQPPPMLSVPLPNIPASNWHAQQLKQLAASKQVSTTKQQVQAPSWPSMSPPGLSPPYRAGSSPHHQPFSPQNVMVSGMPTNNLPGNNIQSPQNTLLSSMTSSSTPSNGPSPPYGSEKLSSPALNQQPFSPQSSMLPALTAASLPASNIKSPQNNLVASMASTNTGPSPPYRPEKLSSPALHQQPFSPQGTLISNITPNNNPPSMQNSLFKSVTTSQSKNMNIIMQQSSASLQPGLVNESPVSQDQFSFSNTKPLSHFASESATQKMSPLTAGQGQQSLIHYLQQQQQQSPAAQQSQQANSSQLLQQQFRQLMQPHRMQRHMQSATLPSQNRQNPGLVARLQEPGSVPGGGSVPAPATVNGYAMRNHLLKQQIMKRQLMQEKQRQNMLGVTSEQRNLFASQQMNQFQAVQQPIPTDCSQPMPAPPPNHHMLPSNPAMLQSTLGTSITPVTANQSSGTMVMIPHNPGKQQTVFPPNSDFNIPLRPSQNSMAMNSGCQTVHSHAAVQPGMPMAGFSSGSLVNHSAAQQHLRQPSVPRIPSVYPNSSAQMWTPTAVPRMPNQSQMDTSMQQFSSNALFSKQNVRPNASGQQFSQQAVVPPNQIAPGVQVRQMQKLSMGQSGQGMSSMNNQNLRHSLTRGPLPAMNVMKSMPQGVSSFNQLNPPTGLGPPTYPAAGQPPDAFSRMSAAAELPQYDFVPQHSSSVLPTNCSDTDFLDSLMKSSSSNDEEWLNNLTMIDDILGQHAQSSGHV", "length": 998, "header": "tr|A0A8V0YAB4-1|A0A8V0YAB4_CHICK Isoform 1 of Mastermind like domain containing 1 OS=Gallus gallus OX=9031 GN=MAMLD1 PE=4 SV=1 CANONICAL=A0A8V0YAB4-1" }, "locus": { "chromosome": "4", "start_pos": 17824701, "end_pos": 17749220, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027773.1", "url": "https://www.ensembl.org/id/ENSGALT00010027773.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015920.1", "url": "https://www.ensembl.org/id/ENSGALP00010015920.1" } ] } }, { "isoform_ac": "A0A8V0YBT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAB4/entry#A0A8V0YBT7-1", "sequence": { "sequence": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAD2-1", "uniprot_ac": "A0A8V0YAD2", "uniprot_id": "A0A8V0YAD2_CHICK", "mass": { "chemical_mass": 21533.0, "monoisotopic_mass": 21533.0 }, "refseq": { "ac": "XP_001237035", "name": "ADP-ribosylation factor-like protein 4C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001237035" }, "gene_names": [ { "name": "ARL4C", "type": "recommended", "evidence": [ { "id": "A0A8V0YAD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ] }, { "name": "ARL4C", "type": "synonym", "evidence": [ { "id": "XP_001237035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001237035" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 4C", "type": "synonym", "evidence": [ { "id": "XP_001237035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001237035" } ] }, { "name": "ARF like GTPase 4C", "type": "synonym", "evidence": [ { "id": "A0A8V0YAD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001237035.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001237035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001237035" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL4C", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2", "locus": { "chromosome": "7", "start_pos": 5779418, "end_pos": 5795594, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012744", "url": "https://www.ensembl.org/id/ENSGALG00010012744" } ] } } ], "crossref": [ { "id": "A0A8V0YAD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000052743", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000052743", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424026", "url": "https://www.ncbi.nlm.nih.gov/gene/424026", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424026", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424026", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IRILWIN", "url": "https://omabrowser.org/oma/group/IRILWIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U5L7", "url": "https://www.orthodb.org/?gene=A0A3Q2U5L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAD2", "url": "https://www.orthodb.org/?gene=A0A8V0YAD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001237035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001237035", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5L7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U5L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIRLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELTPSTTYHIQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR", "length": 192, "header": "tr|A0A8V0YAD2-1|A0A8V0YAD2_CHICK Isoform 1 of ARF like GTPase 4C OS=Gallus gallus OX=9031 GN=ARL4C PE=3 SV=1 CANONICAL=A0A8V0YAD2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U5L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2/entry#A0A3Q2U5L7-1", "sequence": { "sequence": "MLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIRLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELTPSTTYHIQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR", "length": 175, "header": "tr|A0A3Q2U5L7-1|A0A3Q2U5L7_CHICK Computationally mapped isoform of ARF like GTPase 4C OS=Gallus gallus OX=9031 GN=ARL4C PE=3 SV=1 CANONICAL=A0A8V0YAD2-1" }, "locus": { "chromosome": "7", "start_pos": 5783378, "end_pos": 5782854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030522.1", "url": "https://www.ensembl.org/id/ENSGALT00010030522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017702.1", "url": "https://www.ensembl.org/id/ENSGALP00010017702.1" } ] } }, { "isoform_ac": "A0A8V0YAD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2/entry#A0A8V0YAD2-1", "sequence": { "sequence": "MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIRLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELTPSTTYHIQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR", "length": 192, "header": "tr|A0A8V0YAD2-1|A0A8V0YAD2_CHICK Isoform 1 of ARF like GTPase 4C OS=Gallus gallus OX=9031 GN=ARL4C PE=3 SV=1 CANONICAL=A0A8V0YAD2-1" }, "locus": { "chromosome": "7", "start_pos": 5781305, "end_pos": 5780730, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030506.1", "url": "https://www.ensembl.org/id/ENSGALT00010030506.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017689.1", "url": "https://www.ensembl.org/id/ENSGALP00010017689.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424026", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AQK5-1", "protein_name": "ADP ribosylation factor like GTPase 4C", "gene_name": "Arl4c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR", "length": 192 }, "evidence": [ { "id": "A0A8V0YAD2", "url": "https://omabrowser.org/oma/group/A0A8V0YAD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IK77-1", "protein_name": "ADP-ribosylation factor-like protein 4C", "gene_name": "Arl4c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR", "length": 192 }, "evidence": [ { "id": "A0A8V0YAD2", "url": "https://omabrowser.org/oma/group/A0A8V0YAD2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P56559-1", "protein_name": "ADP-ribosylation factor-like protein 4C", "gene_name": "ARL4C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR", "length": 192 }, "evidence": [ { "id": "A0A8V0YAD2", "url": "https://omabrowser.org/oma/group/A0A8V0YAD2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61208-1", "protein_name": "ADP-ribosylation factor-like protein 4C", "gene_name": "Arl4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNISSNISAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCHFWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQDLPKSLPVAEIEKQLALHELIPATTYHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKKR", "length": 192 }, "evidence": [ { "id": "A0A8V0YAD2", "url": "https://omabrowser.org/oma/group/A0A8V0YAD2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A3Q2U5L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5L7#function" }, { "id": "A0A3Q2U5L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U5L7" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 10, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 10, "end_pos": 10, "start_aa": "Ala", 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"start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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{ "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD3" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAD8-1", "uniprot_ac": "A0A8V0YAD8", "uniprot_id": "A0A8V0YAD8_CHICK", "mass": { "chemical_mass": 121135.0, "monoisotopic_mass": 121135.0 }, "refseq": { "ac": "XP_414518", "name": "protocadherin-12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414518" }, "gene_names": [ { "name": "PCDH12", "type": "recommended", "evidence": [ { "id": "A0A8V0YAD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ] }, { "name": "PCDH12", "type": "synonym", "evidence": [ { "id": "XP_414518", "database": "RefSeq", "url": 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Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414518.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414518", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414518" } ] }, { "annotation": "Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Acts as a regulator of cell migration, probably via increasing cell-cell adhesion. Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8#function" }, { "database": "UniProtKB", "id": "ARBA00059072", "url": "https://www.uniprot.org/uniprotkb/ARBA00059072#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCDH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8", "locus": { "chromosome": "13", "start_pos": 2019276, "end_pos": 2030507, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011635", "url": "https://www.ensembl.org/id/ENSGALG00010011635" } ] } } ], "crossref": [ { "id": "A0A8V0YAD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416191", "url": "https://www.ncbi.nlm.nih.gov/gene/416191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416191", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416191", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ALFMSIC", "url": "https://omabrowser.org/oma/group/ALFMSIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAD8", "url": "https://www.orthodb.org/?gene=A0A8V0YAD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414518", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414518", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRQSGEPTATCWAMGTLGGLLLLGRSALQLRALWWLLFLSTDAQEVATITVQYRLFEEVPEGTVIGTLAEHFEHGESGEMGENFRLLQSPGMFPLHVESGDGELSTAGRVDREQLCRHSDPCWVSFDVLAAEQLALIHVEVQVLDINDHAPRFPTPELELEMSESASLQMHIPLDRALDADTGPNAHCSYALSPSEHFALEVVSGSDGTKHAELVVIKEVDRELHSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVREDALLGTLLVTVTATDPDQGPNGEIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEETHAYELDVQARDLGANPIPAHCKVLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALVTASDPDSGNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVARDQGEHSLAVWKHLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVTYSIRDSTVLGLVSIDPISGDITALRAFDHEQMSSLEFLVTAEDGGHPVLASNVTVRLEVLDQNDNAPVVTEPPLVRGMATLSVLVSAETGCVWVTSGNGSAMETVLANVSCSDTPLLFTIVARDGDSGRNGALRYDIMGGDAAGLVVLDPLSGQAFLNASNASRLAGTQQDLAVRISDGGDEPLHTQACVRLLFRQHGAFSKMSAGGPGWLSPPVVAAICLAALLGSCLLLSALTLSLRKKEKKDSMAYNCREAEDARRQQQLKKPPRQIQKADIHLVPTPWGRPRGAEPQQPSVEGSPQPPPLLTPTLYRTLRNQRVSRDSDEEQGMFTLPVVQRRPCPSHRPKNSPTDVVGNLPPEEPPLSAPQPRPPQHILRSLVRLSLVALAEQSPNGEFAMESAPVQQISQLLSLLHQGQFQPKTNHRGNKYTAKNGSRAAGLDADCLSTKDSGHGESEAEDRDSESGFELSVQQLVGEELETLLEPQAELALKRLTADPAWVARLSLPPTGNYKDNVFSPGSLHSSQDEEAVGREKPRTFETFGKGPGSDSNAAGTRLASTFLSEMSTLFEMILSQKVQVHNETGSGLLRQLSARGKSLGLDDSAPVL", "length": 1119, "header": "tr|A0A8V0YAD8-1|A0A8V0YAD8_CHICK Isoform 1 of Protocadherin-12 OS=Gallus gallus OX=9031 GN=PCDH12 PE=4 SV=1 CANONICAL=A0A8V0YAD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8/entry#A0A8V0YAD8-1", "sequence": { "sequence": "MRRQSGEPTATCWAMGTLGGLLLLGRSALQLRALWWLLFLSTDAQEVATITVQYRLFEEVPEGTVIGTLAEHFEHGESGEMGENFRLLQSPGMFPLHVESGDGELSTAGRVDREQLCRHSDPCWVSFDVLAAEQLALIHVEVQVLDINDHAPRFPTPELELEMSESASLQMHIPLDRALDADTGPNAHCSYALSPSEHFALEVVSGSDGTKHAELVVIKEVDRELHSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVREDALLGTLLVTVTATDPDQGPNGEIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEETHAYELDVQARDLGANPIPAHCKVLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALVTASDPDSGNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVARDQGEHSLAVWKHLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVTYSIRDSTVLGLVSIDPISGDITALRAFDHEQMSSLEFLVTAEDGGHPVLASNVTVRLEVLDQNDNAPVVTEPPLVRGMATLSVLVSAETGCVWVTSGNGSAMETVLANVSCSDTPLLFTIVARDGDSGRNGALRYDIMGGDAAGLVVLDPLSGQAFLNASNASRLAGTQQDLAVRISDGGDEPLHTQACVRLLFRQHGAFSKMSAGGPGWLSPPVVAAICLAALLGSCLLLSALTLSLRKKEKKDSMAYNCREAEDARRQQQLKKPPRQIQKADIHLVPTPWGRPRGAEPQQPSVEGSPQPPPLLTPTLYRTLRNQRVSRDSDEEQGMFTLPVVQRRPCPSHRPKNSPTDVVGNLPPEEPPLSAPQPRPPQHILRSLVRLSLVALAEQSPNGEFAMESAPVQQISQLLSLLHQGQFQPKTNHRGNKYTAKNGSRAAGLDADCLSTKDSGHGESEAEDRDSESGFELSVQQLVGEELETLLEPQAELALKRLTADPAWVARLSLPPTGNYKDNVFSPGSLHSSQDEEAVGREKPRTFETFGKGPGSDSNAAGTRLASTFLSEMSTLFEMILSQKVQVHNETGSGLLRQLSARGKSLGLDDSAPVL", "length": 1119, "header": "tr|A0A8V0YAD8-1|A0A8V0YAD8_CHICK Isoform 1 of Protocadherin-12 OS=Gallus gallus OX=9031 GN=PCDH12 PE=4 SV=1 CANONICAL=A0A8V0YAD8-1" }, "locus": { "chromosome": "13", "start_pos": 2030300, "end_pos": 2021158, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027811.1", "url": "https://www.ensembl.org/id/ENSGALT00010027811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015945.1", "url": "https://www.ensembl.org/id/ENSGALP00010015945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416191", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416191", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F5T8-1", "protein_name": "Protocadherin-12", "gene_name": "pcdh12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLQVLLLLAALFECQVCLANNMGSAHLTIQYRVWEEQPPGTRVGRLLDDLRERGETGSLENFQVVQHGHALPVTVASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHLLSVRVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFALDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIHPKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPDSPVATVTEGAPNETFLALVMVSDADYGANGQVQVHILTGSGPFRLKQIHGDNYMIVTNGTLDREKQMEYNLTLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVDLGLSGQVSFSIRESNELGTPTAFFSVHPSSGEVTVQQSLDYEESRVYSFIVEAVDQGYPPMTSIAAVLVEIQDVNDNYPIIYEPLPKKGIALLNVPVNVDKGEIVTELGDKAMEDNFHKHRNYSSLNKPEGFLATTIRASDPDSGLNGRLNFGITGGNPSNIFFLDKTSGEFYVNTTNATELIGRTFKLGIEVSDMGTPILSTRTTLEVTFINFRDHLKNLSHDNQAQYSFTMLLAICLGSTCLVLFLIIALAKTFCHPNKRDNRAYNCRQAESTYTRHPRRPQKHIQKTDIQLVPVLRGRRETSQEDEAEALSSTSPLVEKAHSQSQFTFTPTLARMTQNQAHTEMDGNLPLTQSKILKKPGSIEWNGTLPYTSGTPCRTLQKTRNSSSSSFANSQASTLRRNKIEESKPTSMDTSQTVTSVSSNQATLRRPKTTEKRGRMEESDQRQILRNLVRLSMAAFAENGSFELSSASPEVQQVSQLLSLLHQGQLQPRPNFRGNKYSHRAGRSGAQDADWLSTKDSGHGESEMGDMDWETGRDSPVDHLYEEGLNNLLTSDDVFSDVPDPAWMARLSLPLSTDYHENLFIPDGPPSPDALCTMSSLDDFTSFSTFGKTLESQPLGGRALMSEVSSLFEMLLTQKADAQSCPPADVLYRLSAAYGRSLGLDVPVNGGAVTSRQQAQTSIM", "length": 1174 }, "evidence": [ { "id": "A0A8V0YAD8", "url": "https://omabrowser.org/oma/group/A0A8V0YAD8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MA46-1", "protein_name": "Protocadherin-12", "gene_name": "Pcdh12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TMLLLPFLLGLLGPGSYLFISGACQEVATVTVKFQVAEEVPSGTVIGKLSQEPGVEERRGKAGDAFQILQLPQALPIQMNSEDGLLNTSSRLDREKLCRQQDPCLVSFDVLATGASALIHVEIQVLDINDHQPQFPKDEQELEISESASLHTRIPLDRALDQDTGPNSLYSYSLSPSEHFALDVIVGPDETKHAELVVVKELDREVHSYFDLVLTAYDNGNPPKSGTSVVKVNVLDSNDNSPVFAESSLALEIPEDTAPGTLLINLTATDPDQGPNGEVEFFFGKHVSPEVMNTFGIDAKTGQIVLLQPLDYEKNPAYEVDVQARDLGPNSIPGHCKVLIKVLDVNDNAPSIHITWASQMSLVSEDLPRDSFIALVSANDLDSGNNGLVNCWLNQELGHFRLKRTNGNTYMLLTSAMLDREQWPTYTLTVFAQDQGPQALSAEKELQIQVSDVNDNAPVFEKSRYEVSTWENNPPSLHLITLKAHDADLGSNGKVSYRIKDSPVSHLVIIDSETGEVTAQRSLDYEEMAGFEFQVIAEDRGQPQLSSSISVWVSLLDANDNTPEVIQPALSEGKATLSVLVNASTGHLLLPIESPSGMDPAGTGPTPPKATHSPWSFLLVTIVARDADSGANGELLYSIQSGNDAHLFVLSPSLGQLFINVTNASSLIGSQWDLGIVVEDQGSPSLQTQVSLKVVFVTSMDHLRDSAHEPGILSTPALAMICLAVLLAVFGLILALLVSICRIEKRDNRAYNCREAESMYRHQPKRPQKHIQKADIHLVPMLRAQEDEAEEVRPPHKDTSKETLMEAGWDSCLQAPFHLTPTLYRTLRNQGNQGALAESQEVLQDTFNFLFNHPRQRNASRENLNLPESPPTLRQPLLKPLKVPGSPIARVTGDQGSKEAPQSPPASSATLRRQRNLNGKVSPKGESSPHQILRSLVRLSVAAFAERNPVEELAGDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYSAKPGSSRATIPDTDGLGIRPGGLSEPDLEEGPPSPEEDLSVKRLLEEELSSLLDPNTGLALDKLSPPDPAWMARLSLPLTTNYRDNLSSPDAAASEEPRTFQTFGKTVGPGPELSATGTRLASTFVSEMSSLLEMLLEQNTVPVEAASAALRRLSVCGRTLSLDLATSGASGSEAQLGRKKAAESSLGCGRNL", "length": 1180 }, "evidence": [ { "id": "A0A8V0YAD8", "url": "https://omabrowser.org/oma/group/A0A8V0YAD8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N0X0-1", "protein_name": "Protocadherin-12", "gene_name": "PCDH12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMRFLSLLGLLGPGGYLFLSGDCQEVATLTVRYQVAEEVPSGTVIGKLPQERGREEEPGQAGAAFQVLQLPQGLPIQVDSEDGVLSTGRRLDREQLCRQQDPCLVSFDVLATGERALIHVEIQVLDINDHQPQFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHSYTLSPSEHFALDVIVGPDQTKHAELVVVKELDREIHSYFDLVLTAYDSGNPPKSGTSLVKVSVLDSNDNSPVFAESSLALEIQEDAAPGTLLINLTATDPDQGPNGEVEYFLSKHVPLEVLNTFNIDAKTGQVTLLQHLDYEKNPAYEVDVQARDLGPNPIPAHCKILIKVLDVNDNAPSIHITWASQPLLVSEALPKDSFIALIMANDLDSGNNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPQYTLTLLAQDQGPQPLSDKKQLSIQISDANDNAPVFEKSRYQVSTRENNLPSLHLITIKAHDADLGVNGKISYRIQDSPVAHLVAIDSDTGEVTAQRSLDYEQMASFEFLVIAEDSGQPQLSSSVSVWVSLLDANDNAPEVIHPILSNGRASLSVLVNASTGHLLVPIENPNGLGPAGTDIPLQATSSSRPFLLVTIIARDADSGANGELLYTIRSGNEAGVFVLSPNLGQLFINVTNASSLTGSEWELEIVVEDRGSPSLQTRALLQVLFVTSVDHLRDSAREPGALSTSVLTVICLVVLLAVFGSILALITSICRTEKKDNRAYNCREAESTYRHQPKRPQKQIQKADIQLVPMLRGQVDEPGEVGQPPKHVGEEAMMEAGWDSCLQAPFHLTPTLYRTLRNQGNQGTLAESREVLQDTVNLLFNHPRQRNASRENLHLAEPQPAVGQPRSRLLKAAGSPTGRVPGDQGSEEAPQSPPASSATLRRQRNLNGKVAPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYLAKPGSSRSTIPDTDGPGARAGGQAEPDQEEGPLDPEEDLSVKQLLEEELSNLLDPHTGLALDRLSVPDPAWMARLSLPLSTNYRDNVFSPDAATSEEPRTFQTFGKAPELSPTGTRLASTFLSEMSSLLEMLLEQRPAVPVEAASEVLRRLSVCGRTLSLDLATSGAAGSEGLTGLAGNKGAESRTSSGSSSSRGQWIQEPGTLGDVRKPRP", "length": 1197 }, "evidence": [ { "id": "A0A8V0YAD8", "url": "https://omabrowser.org/oma/group/A0A8V0YAD8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RM49-1", "protein_name": "Protocadherin-12", "gene_name": "PCDH12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMPLLPLLLGLLGPGGSLLLSGDCQEVATLTVKYQVSEEVPAGTVIGKLARELGREERPGLAGGAFQVLQLPQALPIQVDAEDGLLSTGKRLDREQLCRQQDPCLVSFDVLAAGDLALIHVEVQVLDINDHQPQFPKGEQELEISESASLSTRIPLDRALDPDTGPNTLHSYTLSPSEHFALDVIVGPDETKHAELVVVKELDREIRSFFDLVLTAYDSGNPPKSGTSLVKVNVLDSNDNSPVFAESSLALEVQEDTAPGTLLINLTATDPDQGPNGEVEFLLSKHVPPEVLDAFSIDAKTGQVILRQPLDYEKNPAYEVDVQARDLGPNPIPAHCKILIKVLDVNDNAPSIHITWASQPSLVSEALPKDSFVALVTANDLDSGDNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPLYTLTLLAQDRGPQPLSAETLLSIQISDANDNAPVFEKSRYQVSTRENNLPSLHLITIKAHDADLGVNGKISYRIQDSPVSHLVAIDPDTGDVTAQRSLDYEQMAGFEFLVVAEDGGQPQLASSVSVWVSILDANDNAPEVIHPMLSDGKASLSVLVNASTGHLLVPIETPNGPGPAGTNSPPQAAPGSQPFFLATIVARDADSGPNGELLYSIRSGNEACLFVLSPRLGQLFVNTTNASSLIGSAWELEIAVQDGGSPSLQTRALLRVVFVTSADHLRDSAREPGALSTSMLAVICLAVLLAVFGSVLALIMSICRTEKKDHRAYNCREAESSYRHQPKRPQKHIQKADIHLVPVLRGQGEETGDVGPPPKHVSSETSLEAGWDPCLQAPFHLTPTLYRTLRNQGNEGAQAESREVLQDTVNLLFNHPRQRNASRENLNLPEPQAAVGQPRSRPLKVPGSPPGRAPGDQGGPEAPLSPPASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYLAKPGSGRSAIPEPDGPGARAGGQAEPDQEEGLLDPEEDLSVKQLLEEELSSLLDPHTGLTLDRLSVPDPAWMARLSLPLASNYRDNVFSPDAAASEEPRTFQTFGKAPGPELSPTGTRLASTFLSEMSSLLEMLLEQRSAVPVEAASEVLRRLSVCGRTLSLDLATSGASGSEVPGGPAGKKGAEARTNSSSSSSRDLWIQEPGAPGDVRKPTP", "length": 1200 }, "evidence": [ { "id": "A0A8V0YAD8", "url": "https://omabrowser.org/oma/group/A0A8V0YAD8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O55134-1", "protein_name": "Protocadherin-12", "gene_name": "Pcdh12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLLLPFLLGLLGPGSYLFISGDCQEVATVMVKFQVTEEVPSGTVIGKLSQELRVEERRGKAGDAFQILQLPQALPVQMNSEDGLLSTSSRLDREKLCRQEDPCLVSFDVLATGASALIHVEIQVLDINDHQPQFPKDEQELEISESASLHTRIPLDRALDQDTGPNSLYSYSLSPSEHFALDVIVGPDETKHAELVVVKELDRELHSYFDLVLTAYDNGNPPKSGISVVKVNVLDSNDNSPVFAESSLALEIPEDTVPGTLLINLTATDPDQGPNGEVEFFFGKHVSPEVMNTFGIDAKTGQIILRQALDYEKNPAYEVDVQARDLGPNSIPGHCKVLIKVLDVNDNAPSILITWASQTSLVSEDLPRDSFIALVSANDLDSGNNGLVHCWLNQELGHFRLKRTNGNTYMLLTNATLDREQWPIYTLTVFAQDQGPQPLSAEKELQIQVSDVNDNAPVFEKSRYEVSTWENNPPSLHLITLKAHDADLGSNGKVSYRIKDSPVSHLVIIDFETGEVTAQRSLDYEQMAGFEFQVIAEDRGQPQLASSISVWVSLLDANDNAPEVIQPVLSEGKATLSVLVNASTGHLLLPIENPSGMDPAGTGIPPKATHSPWSFLLLTIVARDADSGANGELFYSIQSGNDAHLFFLSPSLGQLFINVTNASSLIGSQWDLGIVVEDQGSPSLQTQVSLKVVFVTSVDHLRDSAHEPGVLSTPALALICLAVLLAIFGLLLALFVSICRTERKDNRAYNCREAESSYRHQPKRPQKHIQKADIHLVPVLRAHENETDEVRPSHKDTSKETLMEAGWDSCLQAPFHLTPTLYRTLRNQGNQGELAESQEVLQDTFNFLFNHPRQRNASRENLNLPESPPAVRQPLLRPLKVPGSPIARATGDQDKEEAPQSPPASSATLRRQRNFNGKVSPRGESGPHQILRSLVRLSVAAFAERNPVEEPAGDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYLAKPGGSSRGTIPDTEGLVGLKPSGQAEPDLEEGPPSPEEDLSVKRLLEEELSSLLDPNTGLALDKLSPPDPAWMARLSLPLTTNYRDNLSSPDATTSEEPRTFQTFGKTVGPGPELSPTGTRLASTFVSEMSSLLEMLLGQHTVPVEAASAALRRLSVCGRTLSLDLATSGASASEAQGRKKAAESRLGCGRNL", "length": 1180 }, "evidence": [ { "id": "A0A8V0YAD8", "url": "https://omabrowser.org/oma/group/A0A8V0YAD8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NPG4-1", "protein_name": "Protocadherin-12", "gene_name": "PCDH12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQLLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVICLAVLLGIFGLILALFMSICRTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPVLRGQAGEPCEVGQSHKDVDKEAMMEAGWDPCLQAPFHLTPTLYRTLRNQGNQGAPAESREVLQDTVNLLFNHPRQRNASRENLNLPEPQPATGQPRSRPLKVAGSPTGRLAGDQGSEEAPQRPPASSATLRRQRHLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYLAKPGGSRSAIPDTDGPSARAGGQTDPEQEEGPLDPEEDLSVKQLLEEELSSLLDPSTGLALDRLSAPDPAWMARLSLPLTTNYRDNVISPDAAATEEPRTFQTFGKAEAPELSPTGTRLASTFVSEMSSLLEMLLEQRSSMPVEAASEALRRLSVCGRTLSLDLATSAASGMKVQGDPGGKTGTEGKSRGSSSSSRCL", "length": 1184 }, "evidence": [ { "id": "A0A8V0YAD8", "url": "https://omabrowser.org/oma/group/A0A8V0YAD8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAD8" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion 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"database": "UniProtKB", "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CECR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7", "locus": { "chromosome": "1", "start_pos": 61833025, "end_pos": 61741076, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011637", "url": "https://www.ensembl.org/id/ENSGALG00010011637" } ] } } ], "crossref": [ { "id": "cd05509", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05509", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418161", "url": "https://www.ncbi.nlm.nih.gov/gene/418161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HQGMRYP", "url": "https://omabrowser.org/oma/group/HQGMRYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAE7", "url": "https://www.orthodb.org/?gene=A0A8V0YAE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAF2", "url": "https://www.orthodb.org/?gene=A0A8V0YAF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBW6", "url": "https://www.orthodb.org/?gene=A0A8V0YBW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47092:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47092:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPEEDGGCGGGGGGGGVAGTGGTEAAAALDELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITSQTFHSYLEDIINYRWELEEGKPNPLRESTFQELPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDSSGALYWYFYGTRMYKEDPVQAKTNGELAPDRGCGGQTNTPNVPGKTGKRRGRPPKRKKLLEENLLREKAEENLLIRETQIRNGSQGPGRGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKEKRLQRTEFSPRWMSDHQPIKPIKQEVNPNVLSSMEKQRRREEEEERQILLAVQKREQEQLLKEERKREMEEKVKAVEERARRRKLREERAWLLAQGKELPPELSHLDPSSPTREERRTKDLFELDDEFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGQYCTKEEFVGDMKTMFRNCLKYNGEGSEYTKMAYNLERCFHRAMMKHFPGEDGDTDEEFWIREDGRREKRSRRTGRSSGGNVWTRSRDSEGPGKRQQRLENGGKPPPYRATSRAPASSSSSSSSSFSSSSAEDPSGNSLQPPREVGPSNGRGFPRSLQYGGMPSPVPHPGQMRPAVPGTFGPLRGSDPTKLYGSPRVPEPHPGDPVQQHQHFAMQPAVGLSEHRGHRLATPEKQVCAGPTHIAGLGPRPSALQLGCMSGPPPDAVYSPAQFQQGFLPPRHNGPPVRPPEGSEMPPGHMYRPYKYLNRGHPALWNGSHGASSQSAVGAEEKAPMGPAPSLQPRTIGHMMEPRAIRPPLPPSQWTEQSNFLPHGVPPSGYIRPPGKTTSQRMPQPPAALFGGPPQVQRGCQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPRQPPPPHLPGPFPQLAHAASTGVPPPKPVVGNGSSQDQTMEPESNQVEPLAGVEEKAQCIGIPDRAYAKLLPHPKPPLPMECARRNLPPDGEGDGSGLKSDLKANQSKGTWPAESSYAGPGAQGCMRDLASTPERGGPVSENGAAGEGPAESKGLAASLMEKPLCSGGKALPEAAVPCMGQGTNLPAMDAGTVGAAPNQFHPLYMPGLEYPNSAARYHINPGLQGFSPVMGGKPPPVSHPQHFPARGFQPSNAHPGVFPRYRPHQGMPYPYQPQPQPSYHHYQRPPYYACPQGYSDWQRPLHPQASPSGHPPLARPPFSDRGNVSSLQGCEALSAALASPNRMDVASAKEVSPSDGRDLGPEDEKSEESQERPESPKEFLDLDNHNAATKRQSSVAAGEFLYGAPPPHLGSGMGFGPSAFPPHGVMLQTGSPYASRHPAGHFQPRTYGSPMNAHLSHHPAPGQANGLSQEGPLYRCREENIGHFQALLMEQRGSGGGMGGPPQDLYRPSGMQMHQAQVPFPKMPTATMSREDLTPQKSSALPLDQVRTTKESRAQPFFLLCQLKE", "length": 1493, "header": "tr|A0A8V0YAE7-1|A0A8V0YAE7_CHICK Isoform 1 of Chromatin remodeling regulator CECR2 OS=Gallus gallus OX=9031 GN=CECR2 PE=4 SV=1 CANONICAL=A0A8V0YAE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7/entry#A0A8V0YAE7-1", "sequence": { "sequence": "MCPEEDGGCGGGGGGGGVAGTGGTEAAAALDELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITSQTFHSYLEDIINYRWELEEGKPNPLRESTFQELPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDSSGALYWYFYGTRMYKEDPVQAKTNGELAPDRGCGGQTNTPNVPGKTGKRRGRPPKRKKLLEENLLREKAEENLLIRETQIRNGSQGPGRGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKEKRLQRTEFSPRWMSDHQPIKPIKQEVNPNVLSSMEKQRRREEEEERQILLAVQKREQEQLLKEERKREMEEKVKAVEERARRRKLREERAWLLAQGKELPPELSHLDPSSPTREERRTKDLFELDDEFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGQYCTKEEFVGDMKTMFRNCLKYNGEGSEYTKMAYNLERCFHRAMMKHFPGEDGDTDEEFWIREDGRREKRSRRTGRSSGGNVWTRSRDSEGPGKRQQRLENGGKPPPYRATSRAPASSSSSSSSSFSSSSAEDPSGNSLQPPREVGPSNGRGFPRSLQYGGMPSPVPHPGQMRPAVPGTFGPLRGSDPTKLYGSPRVPEPHPGDPVQQHQHFAMQPAVGLSEHRGHRLATPEKQVCAGPTHIAGLGPRPSALQLGCMSGPPPDAVYSPAQFQQGFLPPRHNGPPVRPPEGSEMPPGHMYRPYKYLNRGHPALWNGSHGASSQSAVGAEEKAPMGPAPSLQPRTIGHMMEPRAIRPPLPPSQWTEQSNFLPHGVPPSGYIRPPGKTTSQRMPQPPAALFGGPPQVQRGCQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPRQPPPPHLPGPFPQLAHAASTGVPPPKPVVGNGSSQDQTMEPESNQVEPLAGVEEKAQCIGIPDRAYAKLLPHPKPPLPMECARRNLPPDGEGDGSGLKSDLKANQSKGTWPAESSYAGPGAQGCMRDLASTPERGGPVSENGAAGEGPAESKGLAASLMEKPLCSGGKALPEAAVPCMGQGTNLPAMDAGTVGAAPNQFHPLYMPGLEYPNSAARYHINPGLQGFSPVMGGKPPPVSHPQHFPARGFQPSNAHPGVFPRYRPHQGMPYPYQPQPQPSYHHYQRPPYYACPQGYSDWQRPLHPQASPSGHPPLARPPFSDRGNVSSLQGCEALSAALASPNRMDVASAKEVSPSDGRDLGPEDEKSEESQERPESPKEFLDLDNHNAATKRQSSVAAGEFLYGAPPPHLGSGMGFGPSAFPPHGVMLQTGSPYASRHPAGHFQPRTYGSPMNAHLSHHPAPGQANGLSQEGPLYRCREENIGHFQALLMEQRGSGGGMGGPPQDLYRPSGMQMHQAQVPFPKMPTATMSREDLTPQKSSALPLDQVRTTKESRAQPFFLLCQLKE", "length": 1493, "header": "tr|A0A8V0YAE7-1|A0A8V0YAE7_CHICK Isoform 1 of Chromatin remodeling regulator CECR2 OS=Gallus gallus OX=9031 GN=CECR2 PE=4 SV=1 CANONICAL=A0A8V0YAE7-1" }, "locus": { "chromosome": "1", "start_pos": 61832771, "end_pos": 61741077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027822.1", "url": "https://www.ensembl.org/id/ENSGALT00010027822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015955.1", "url": "https://www.ensembl.org/id/ENSGALP00010015955.1" } ] } }, { "isoform_ac": "A0A8V0YAF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7/entry#A0A8V0YAF2-1", "sequence": { "sequence": "MCPEEDGGCGGGGGGGGVAGTGGTEAAAALDELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITSQTFHSYLEDIINYRWELEEGKPNPLRESTFQELPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDSSGALYWYFYGTRMYKEDPVQAKTNGELAPDRGCGGQTNTPNVPGKTGKRRGRPPKRKKLLEENLLREKAEENLLIRETQIRNGSQGPGRGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKEKRLQRTEFSPRWMSDHQPIKPIKQEVNPNVLSSMEKQRRREEEEERQILLAVQKREQEQLLKEERKREMEEKVKAVEERARRRKLREERAWLLAQGKELPPELSHLDPSSPTREERRTKDLFELDDEFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGQYCTKEEFVGDMKTMFRNCLKYNGEGSEYTKMAYNLERCFHRAMMKHFPGEDGDTDEEFWIREDGRREKRSRRTGRSSGGNVWTRSRDSEGPGKRQQRLENGGKPPPYRATSRAPASSSSSSSSSFSSSSAEDPSGNSLQPPREVGPSNGRGFPRSLQYGGMPSPVPHPGQMRPAVPGTFGPLRGSDPTKLYGSPRVPEPHPGDPVQQHQHFAMQPAVGLSEHRGHRLATPEKQVCAGPTHIAGLGPRPSALQLGCMSGPPPDAVYSPAQFQQGFLPPRHNGPPVRPPEGSEMPPGHMYRPYKYLNRGHPALWNGSHGASSQSAVGAEEKAPMGPAPSLQPRTIGHMMEPRAIRPPLPPSQWTEQSNFLPHGVPPSGYIRPPGKTTSQRMPQPPAALFGGPPQVQRGCQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPRQPPPPHLPGPFPQLAHAASTGVPPPKPVVGNGSSQDQTMEPESNQVEPLAGVEEKAQCIGIPDRAYAKLLPHPKPPLPMECARRNLPPDGEGDGSGLKSDLKANQSKGTWPAESSYAGPGAQGCMRDLASTPERGGPVSENGAAGEGPAESKGLAASLMEKPLCSGGKALPEAAVPCMGQGTNLPAMDAGTVGAAPNQFHPLYMPGLEYPNSAARYHINPGLQGFSPVMGGKPPPVSHPQHFPARGFQPSNAHPGVFPRYRPHQGMPYPYQPQPQPSYHHYQRPPYYACPQGYSDWQRPLHPQASPSGHPPLARPPFSDRGNVSSLQGCEALSAALASPNRMDVASAKEVSPSDGRDLGPEDEKSEESQERPESPKEFLDLDNHNAATKRQSSVAAGEFLYGAPPPHLGSGMGFGPSAFPPHGVMLQTGSPYASRHPAGHFQPRTYGSPMNAHLSHHPAPGQANGLSQEGPLYRCREENIGHFQALLMEQRGSGGGMGGPPQDLYRPSGMQMHQAQVPFPKMPTATMSREDLTPQKSSALPLDQS", "length": 1474, "header": "tr|A0A8V0YAF2-1|A0A8V0YAF2_CHICK Computationally mapped isoform of Chromatin remodeling regulator CECR2 OS=Gallus gallus OX=9031 GN=CECR2 PE=4 SV=1 CANONICAL=A0A8V0YAE7-1" }, "locus": { "chromosome": "1", "start_pos": 61833001, "end_pos": 61741077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027831.1", "url": "https://www.ensembl.org/id/ENSGALT00010027831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015960.1", "url": "https://www.ensembl.org/id/ENSGALP00010015960.1" } ] } }, { "isoform_ac": "A0A8V0YBW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7/entry#A0A8V0YBW6-1", "sequence": { "sequence": "MCPEEDGGCGGGGGGGGVAGTGGTEAAAALDELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITSQTFHSYLEDIINYRWELEEGKPNPLRESTFQELPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDSSGALYWYFYGTRMYKEDPVQAKTNGELAPDRGCGGQTNTPNVPGKTGKRRGRPPKRKKLLEENLLREKAEENLLIRETQIRNGSQGPGRGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKVNPNVLSSMEKQRRREEEEERQILLAVQKREQEQLLKEERKREMEEKVKAVEERARRRKLREERAWLLAQGKELPPELSHLDPSSPTREERRTKDLFELDDEFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGQYCTKEEFVGDMKTMFRNCLKYNGEGSEYTKMAYNLERCFHRAMMKHFPGEDGDTDEEFWIREDGRREKRSRRTGRSSGGNVWTRSRDSEGPGKRQQRLENGGKPPPYRATSRAPASSSSSSSSSFSSSSAEDPSGNSLQPPREVGPSNGRGFPRSLQYGGMPSPVPHPGQMRPAVPGTFGPLRGSDPTKLYGSPRVPEPHPGDPVQQHQHFAMQPAVGLSEHRGHRLATPEKQVCAGPTHIAGLGPRPSALQLGCMSGPPPDAVYSPAQFQQGFLPPRHNGPPVRPPEGSEMPPGHMYRPYKYLNRGHPALWNGSHGASSQSAVGAEEKAPMGPAPSLQPRTIGHMMEPRAIRPPLPPSQWTEQSNFLPHGVPPSGYIRPPGKTTSQRMPQPPAALFGGPPQVQRGCQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPRQPPPPHLPGPFPQLAHAASTGVPPPKPVVGNGSSQDQTMEPESNQVEPLAGVEEKAQCIGIPDRAYAKLLPHPKPPLPMECARRNLPPDGEGDGSGLKSDLKANQSKGTWPAESSYAGPGAQGCMRDLASTPERGGPVSENGAAGEGPAESKGLAASLMEKPLCSGGKALPEAAVPCMGQGTNLPAMDAGTVGAAPNQFHPLYMPGLEYPNSAARYHINPGLQGFSPVMGGKPPPVSHPQHFPARGFQPSNAHPGVFPRYRPHQGMPYPYQPQPQPSYHHYQRPPYYACPQGYSDWQRPLHPQASPSGHPPLARPPFSDRGNVSSLQGCEALSAALASPNRMDVASAKEVSPSDGRDLGPEDEKSEESQERPESPKEFLDLDNHNAATKRQSSVAAGEFLYGAPPPHLGSGMGFGPSAFPPHGVMLQTGSPYASRHPAGHFQPRTYGSPMNAHLSHHPAPGQANGLSQEGPLYRCREENIGHFQALLMEQRGSGGGMGGPPQDLYRPSGMQMHQAQVPFPKMPTATMSREDLTPQKSSALPLDQS", "length": 1448, "header": "tr|A0A8V0YBW6-1|A0A8V0YBW6_CHICK Computationally mapped isoform of Chromatin remodeling regulator CECR2 OS=Gallus gallus OX=9031 GN=CECR2 PE=4 SV=1 CANONICAL=A0A8V0YAE7-1" }, "locus": { "chromosome": "1", "start_pos": 61833001, "end_pos": 61741077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027836.1", "url": "https://www.ensembl.org/id/ENSGALT00010027836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015963.1", "url": "https://www.ensembl.org/id/ENSGALP00010015963.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E9Q2Z1-1", "protein_name": "Chromatin remodeling regulator CECR2", "gene_name": "Cecr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGRSNGELSLCRESERQKNVSNVPGKTGKRRGRPPKRKKLQEEIISSEKQEENSLTSDLQTRNGSRGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKPELQHRFMSDHLSIKSIKLEETPMLTKIEKQKRREEEEERQLLLAVQKKEQEQMLKEERKREMEEKVKAVEDRAKRRKLREERAWLLAQGKELPPELSHLDLNSPMREGKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKIPMDISSMEKKLNGGLYCNKEEFVNDMKTMFRNCRKYNGDSSEYTKMSDNLERCFHRAMTKHFPGEDGDTDEEFWIKEDEKREKRRSRSGRSSGSHVWTRSRDTEGSSRKQPPVENGGKSLPPARRAASSGDDQSRSSIQLPPEVGTSHGQGFSRPLHCGRVPSHAPPLNQMRPAAPGTFGSLQGSDPTNLHGSSRIPEAPPGEPLQHPPFAIQAPVGISNHRGSLLSAPDLSNMGSHVPSLQLGQMNCPSQDGNMYPPAPFQAGFIPSRHGGTPARPPDFPESSEIPPGHIYHSYKYLNRAHPAVWNGNHGTTNPGRLGPDEKPHLGPGPSHHPHTLGHMMDGRVMRQPIPPNQWTKQSSFLPHGVPSSGYMQPPCKSAGHRLQPPPTPAPSPRFRGPSQALRGAQGGESMMDSPEMIAMQQLSSRVCPPGVPYHPRQPTPPQLPGPFPQVAHSASVCVSAPKPALDNPGSTQEMTETHEPEEDPAEPLPGHEEKAASICSSEGVYLKQLPHPAPPLQASCTRQSSPQERETEDSQLKSDASDSADTYKTSKNKNTWPLDNSYSSPAVQGCLRDLSIVAETGNLPENGVVGEASPCRSEGKGLDGSGSEKPLCPRGKTLQEAVPCTGPNATTPPCTDPSLMAATVNQFSPLYMPGIEYSNSATQYPMSPSLQGLASMMGGKSSGSQPQSFPPRGFQANGPHPGLFPRYRPQQGMRYSYQPPSQPSYHPYQRTPYYTCPQGFSDWQRSLPSQRSPSGPPGSHPPRSLFSEKNVLSSLQGCETLNTALTSPTQMDVVTAKVVPPDGHNSGPEEEKMDESVERPESPKEFLDLDNHNAATKRQNSLSTSDYLYGTPPPSLSSGMTFGSSAFPPHSVMLQTGSPYTPQRSASHFQPRAYPSPVPAHPPPHPVATQPNGLSPEDSLYCCQEEGLGHFQASMMEQTGTGSGLRGSFQEVHRPPGLQMHPVQSQSLFPKTPAPAASPEQLPPHKTPTLPLDQS", "length": 1453 }, "evidence": [ { "id": "A0A8V0YAE7", "url": "https://omabrowser.org/oma/group/A0A8V0YAE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LYI0-1", "protein_name": "Chromatin remodeling regulator CECR2", "gene_name": "Cecr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVDFISDLIACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGRSNGELSLSRESERQKNVSNVPGKTGKRRGRPPKRKKLQEEIISSEKQEENSLTSDLQTRNGSRGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKPELQHRFMSDHLSIKSTKLEETPMLTKIEKQKRKEEEEERQLLLAVQKKEQEQMLKEERKRELEEKVKAVEDRAKRRKLREERAWLLAQGKELPPELSHLDLNSPMREGKKTKDIFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKIPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGDSSEYTKMSENLERCFHRAMTKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSSGSHVWTRSRDTEGSSRKQPPMENGGKSLPPARRAASSGDDQSSSSIQLPPEVGTSNGRGFFHPLHYSRVPSQAPPLNQMRPAASGTFGSLQGSDPTNLHGSSRIPEVPPGEPLQHPPFAIQAPVGISNHRGSRLSAPEEKMCGGLTHLSNMGSHVPSLQLGQMNCNSQDGNIYPPAPFQAGFIPSRHGGTPARPPDFPESSEIPPSHIYHSYKYLNRVHPAVWNGNHGTTNPGRLGPDEKPLVGPGASHHPHALGHMMDGRVMRQPIPPNQWTKQSSFLPPGVPSSGYMQPPCKSAGHRLQPPPTPAPSPRFRGPSQALRGAQGGESMMDSPEMIAMQQLSSRVCPPGVPYHPRQPTPPQLPGPFPQVAHSASVCVSAPKPALDNPGSTQEISETQEPEGDRAEPVPGLEEKAASICSSEGLYLKQLPHPAPPLSASCTRQSSPHERETEDSQLKSDASDSADTYKASKNKNPWPLDNSYNSAAVQGALHGGRDLAIVTERGNLPENGVVGEASPCRSEGKGLGGSGSEKPLCPRGKTLQETVPCTGQNATTPPCTDPNLMAGTVNQFSPLYMPGIEYSNSATHYPMSPSLQGLGSMMGAKSPGSQPQSFSPRSFQANGPHPGLFPRYRPQQGMRYSYQPSSQPSYHPYQRTPYYTCPQGFSDWQRSLPSQRSPSGPPGSHPPRPLFSDKNALTSLQGCETLNAALTSPTQMDAVAAKVVPPDGHNSGPEEEKMDESMERPESPKEFLDLDNHNAATKRQSSLSTNDYLYGAPPPPLSSGMTFGSSAFPPHSVMLQTGSPYTPQRSASHFQPRAYASPVPAHPPPHPVATQPNGLSPEGPLYCCQEEGLGHFQAAMMEQTGTGSGIRGSFQDAHRPPGLQMHPIQSQSLFPKTPAPAASPEQLPPHKAPTLPLDQS", "length": 1465 }, "evidence": [ { "id": "A0A8V0YAE7", "url": "https://omabrowser.org/oma/group/A0A8V0YAE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BXF3-1", "protein_name": "Chromatin remodeling regulator CECR2", "gene_name": "CECR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSLSRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS", "length": 1484 }, "evidence": [ { "id": "A0A8V0YAE7", "url": "https://omabrowser.org/oma/group/A0A8V0YAE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" } ], "pmid": "" }, { "name": "execution phase of apoptosis", "id": "GO:0097194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" } ], "pmid": "" }, { "name": "CERF complex", "id": "GO:0090537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1251, "end_pos": 1253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 960, "end_pos": 962, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAE7" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 449, "end_pos": 519, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1033, "end_pos": 1035 }, { "start_pos": 1251, "end_pos": 1253 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 960, "end_pos": 962 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YAK6/entry#names_and_taxonomy" } ] }, { "name": "Photoreceptor-associated LRR superfamily protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6/entry#names_and_taxonomy" } ] }, { "name": "Retina-specific protein PAL", "type": "synonym", "evidence": [ { "id": "A0A8V0YAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_040530899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530899" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052578.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040530899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530899" } ] }, { "annotation": "Photoreceptor synaptic protein essential for normal vision. Involved in synapse formation in cone photoreceptor cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6#function" }, { "database": "UniProtKB", "id": "ARBA00058974", "url": "https://www.uniprot.org/uniprotkb/ARBA00058974#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRIT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6", "locus": { "chromosome": "6", "start_pos": 3726731, "end_pos": 3692470, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010854", "url": "https://www.ensembl.org/id/ENSGALG00010010854" } ] } } ], "crossref": [ { "id": "A0A8V0YAK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428935", "url": "https://www.ncbi.nlm.nih.gov/gene/428935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IVCVCVK", "url": "https://omabrowser.org/oma/group/IVCVCVK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAK6", "url": "https://www.orthodb.org/?gene=A0A8V0YAK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040530899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWIAVSLLCCLVLGGLPPAGTSCPSQCSCAFHSLNEGTKARTVLCNDPEMTLTPVNIPVDTFKLRIEKTAIRRVPGEAFHALHNLEYLWLPYNSLASLSGITFKGLRRLLELRLDGNDLISFPWETLSDMPQLRLLDLHNNELTSIPPDAARYIKNITYLDLSSNKLMTLPQALISTWANLQAVPYFPNDNSKIILGLQDNPWACDCSLYEMVHFLNFQSPNIAFIEPRLKCFTPRSLAGVFFSQVELRKCQSPVVHTSVAKVKTILGSTVLLRCGTTGVPIPELSWRRADGAPLNGTVHQEISSDGMSWSILGLPVVSYLDSGEYICKAKNFLGATEAFISLIIMDSESTDDPNPNAKGTWSGKASGMEAAAYNDKLVARYVITTSTMPTLGAGAGTGEDVLIPAGAQDSNPQNLLVSPPTGQQEPERIVRSVRVIGDTDQSVTLAWKAPLAKNTTVFSVLYAVFGERDMRRINVEPGKTKVSIYGLLPKTKYIVCVCVKGLIPRKEQCIIFSTDEVASAGGTQKLINVVVISVACVIAVPLTLVVCCGALKRRCKKCFVRKPKEIQESYVTFESLSPGAKVKGVEGEYLTRHTPDESNRLLSARSSVDSEAIPKIEGQPNEYFC", "length": 626, "header": "tr|A0A8V0YAK6-1|A0A8V0YAK6_CHICK Isoform 1 of Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LRIT1 PE=4 SV=1 CANONICAL=A0A8V0YAK6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6/entry#A0A8V0YAK6-1", "sequence": { "sequence": "MWIAVSLLCCLVLGGLPPAGTSCPSQCSCAFHSLNEGTKARTVLCNDPEMTLTPVNIPVDTFKLRIEKTAIRRVPGEAFHALHNLEYLWLPYNSLASLSGITFKGLRRLLELRLDGNDLISFPWETLSDMPQLRLLDLHNNELTSIPPDAARYIKNITYLDLSSNKLMTLPQALISTWANLQAVPYFPNDNSKIILGLQDNPWACDCSLYEMVHFLNFQSPNIAFIEPRLKCFTPRSLAGVFFSQVELRKCQSPVVHTSVAKVKTILGSTVLLRCGTTGVPIPELSWRRADGAPLNGTVHQEISSDGMSWSILGLPVVSYLDSGEYICKAKNFLGATEAFISLIIMDSESTDDPNPNAKGTWSGKASGMEAAAYNDKLVARYVITTSTMPTLGAGAGTGEDVLIPAGAQDSNPQNLLVSPPTGQQEPERIVRSVRVIGDTDQSVTLAWKAPLAKNTTVFSVLYAVFGERDMRRINVEPGKTKVSIYGLLPKTKYIVCVCVKGLIPRKEQCIIFSTDEVASAGGTQKLINVVVISVACVIAVPLTLVVCCGALKRRCKKCFVRKPKEIQESYVTFESLSPGAKVKGVEGEYLTRHTPDESNRLLSARSSVDSEAIPKIEGQPNEYFC", "length": 626, "header": "tr|A0A8V0YAK6-1|A0A8V0YAK6_CHICK Isoform 1 of Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LRIT1 PE=4 SV=1 CANONICAL=A0A8V0YAK6-1" }, "locus": { "chromosome": "6", "start_pos": 3726297, "end_pos": 3715685, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025983.1", "url": "https://www.ensembl.org/id/ENSGALT00010025983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014642.1", "url": "https://www.ensembl.org/id/ENSGALP00010014642.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BKZ2-1", "protein_name": "Leucine rich repeat, Ig-like and transmembrane domains 1", "gene_name": "LRIT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRVVVGMLWLLALGGPPQAQGACPSQCSCSLHVLSDGSKARTVVCNDPDMTLPPASVPLDTSKLRLERTAIRRVPGDAFKTLGRLEQLWLPYNALCELSALMLRGLRRLRELRMPGNRLAAFPWAALRDAPQLRLLDLQANRLSAVPPEAARFLGNLTFLDLSSNQLLRLPQELLATWIHLHTGPFLPGHHARLVLGLQDNPWVCDCRLYDLVHFLEGWAPNLAFIEARLRCASPRSLAGVVFSQLELRKCQSPELHPGMTSIRSPLGSRVLLRCGATGVPGPEMSWSRANGHPLNGTVHQEVSSDGTSWALLGLPAVSQLDSGDYICQAKNFLGASETLISLVVTEPQTSTERSGGPGARWARTGEGAEAAAYNKMVARHVPHVPEPGVPATGPPVPNAKEQLFLQHFQMRPPEEHSDVPAGSHEAQTVSSLKVVGDTYQSVTLVWKAPQAGNTTALSVLYAVFGKRDMRRVLVQPGKTSVTIRGLVPKVKYVACVCVRGLVPRKEQCVIFSTDEVVDAEATQRLINVVVISVAAVIALPLTLLVCCGAVRRRWRKCHAGGSAEATGAYVNLERLGHSEDGSEDLSQHSLSEADRLLSARSSLDSQAVGIRASRRINEYFC", "length": 622 }, "evidence": [ { "id": "A0A8V0YAK6", "url": "https://omabrowser.org/oma/group/A0A8V0YAK6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K099-1", "protein_name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1", "gene_name": "Lrit1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWVALGMLWLLALGGPHQAWGFCPSECSCSLRILSDGSKARTVVCSDPDLTLPPASIPPDTCKLRLERTAIRRVPGETFRPLSRLEQLWLPYNALSELSALMLRGLRRLRELRLPGNRLVTFPWAALRDTPQLQLLDLQANRLSTLPPEAAHFLENLTFLDLSNNQLMRLPEELLDVWAHLKTGPFLSGHHARLILGLQDNPWVCDCRLYDLVHLLDGWVSSNLIFIEARLRCASPRSLAGVAFSQLELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRRANGRPLNGTVHQEVSSDGSSWTLLDLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTGYSGIPGVLWARTGEGAEAAAYNNKLVARHVPHMPEHVALATKPSMPSIKEELALQNFQMDVPGEFSREPSEHQEAQMVRSLKVVGDTYHSVSLVWKAPQAGNTTAFSVLYAVFGHRDMRRMTVEPGKTSVTIEGLAPKTKYVACVCVRGLVPTKEQCVIFSTDEVVDAEGTQRLINMVVISVAAIIALPPTLLVCCGALRRRCHKCRTGGSAEASGAYVNLERLGHSEDSSEVLSRSSLSEGDRLLSARSSLDSQVLGVRGGRRINEYFC", "length": 624 }, "evidence": [ { "id": "A0A8V0YAK6", "url": "https://omabrowser.org/oma/group/A0A8V0YAK6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JMH2-1", "protein_name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1", "gene_name": "Lrit1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWVALGMLWLLALGGPHQAWSFCPSQCSCSLHILSDGSKARTVVCSDPDLTLPPASIPPDTCKLRLERTAIRRVPGETFRPLSRLEQLWLPYNALSELSTLMLRGLRRLRELRLPGNHLVTFPWAALKDTPQLQLLDLQANRLSTLPPEAVHFLENLTFLDLSNNQLMRLPEELLDTWAHLKTGPYLSSRRTRLVLGLQDNPWVCDCRLYDLVHLLDGWASNLIFIEARLRCGSPRSLAGVAFSQLELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRRANGRPLNGTVHQEVSSDGSSWTLLDLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTEYTGIPGALWARTGEGAEAAAYNNKLVARHVPHVPEPVALATKPSVPSIKEELPLQNFQMDVPGEFSREPSEHQETQMVRSLKVVGDTYHSVSLVWKAPQAGNTTAFSVLYAVFGQRDMRRMTVEAGKTSVTIEGLAPKTKYVACVCVRGLVPTKEQCVIFSTDEVVDAEGTQRLINMVVISVAAIIALPPTLLVCCGALRRRCHKCRAGGSAEASGAYVNLERLGHSEDGSEELSRSSLSEADRLLSARSSLDSQVLGVRGGRRINEYFC", "length": 623 }, "evidence": [ { "id": "A0A8V0YAK6", "url": "https://omabrowser.org/oma/group/A0A8V0YAK6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P2V4-1", "protein_name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1", "gene_name": "LRIT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVALGMLWLLALAWPPQARGFCPSQCSCSLHIMGDGSKARTVVCNDPDMTLPPASIPPDTSRLRLERTAIRRVPGEAFRPLGRLEQLWLPYNALSELNALMLRGLRRLRELRLPGNRLAAFPWAALRDAPKLRLLDLQANRLSAVPAEAARFLENLTFLDLSSNQLMRLPQELIVSWAHLETGIFPPGHHPRRVLGLQDNPWACDCRLYDLVHLLDGWAPNLAFIETELRCASPRSLAGVAFSQLELRKCQGPELHPGVASIRSLLGGTALLRCGATGVPGPEMSWRRANGRPLNGTVHQEVSSDGTSWTLLGLPAVSHLDSGDYICQAKNFLGASETVISLIVTEPPTSTEHSGSPGALWARTGGGGEAAAYNNKLVARHVPQIPKPAVLATGPSVPSTKEELTLEHFQMDALGELSDGRAGPSEARMVRSVKVVGDTYHSVSLVWKAPQAKNTTAFSVLYAVFGQHSMRRVIVQPGKTRVTITGLLPKTKYVACVCVQGLVPRKEQCVIFSTNEVVDAENTQQLINVVVISVAIVIALPLTLLVCCSALQKRCRKCFNKDSTEATVTYVNLERLGYSEDGLEELSRHSVSEADRLLSARSSVDFQAFGVKGGRRINEYFC", "length": 623 }, "evidence": [ { "id": "A0A8V0YAK6", "url": "https://omabrowser.org/oma/group/A0A8V0YAK6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6" } ], "pmid": "" }, { "name": "synaptic cleft", "id": "GO:0043083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAK6" }, { "id": "PS50853", "database": 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This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015144846.1. 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17335", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423978", "url": "https://www.ncbi.nlm.nih.gov/gene/423978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423978", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMLLYHG", "url": "https://omabrowser.org/oma/group/LMLLYHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAM6", "url": "https://www.orthodb.org/?gene=A0A8V0YAM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ09", "url": "https://www.orthodb.org/?gene=A0A8V0YJ09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNT3", "url": "https://www.orthodb.org/?gene=A0A8V0YNT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16172:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16172:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144846", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADDKVAILTDDEEEQKRKYVLADPFNGISKDQDLHPQNESPSTETTTVPDEELDWLEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVRPATLRCVPKGLPPAHPTNASSLLTTISQNTSVSSPLTAISTVSPKVRGKRDLLTSRPVTLGVTGTAAPEVTFLLPTQSGNVEFALENSTHFLLKNTTVTASPGNVTPSTTTLSATTTKPVPSDQAVLVYDQQEVEAIFLLILLVVITGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIEVAIEGQGCKAPEYKNYRIVFIVFGVLMTMALIVATQFRFHYTHFKQDENKRKEVEISQVDRNASNESSDNTPTTSMSQSQSFSFWDLIKLLCSIQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELVGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMVGGVLVNYFGPAATFRGIGMACLVILLLFALIQWLLVPDEEEEKTMLAERIPVPSSPVPIATIDLVQQQSEDVMPRTEPRLPLKKTKHQEEQEDVNKPAWGVSSSPWVTLAYAIYQIKEMVKLSKTHPLPENQPLQKISENCSALASSERQPPTATDSGQPRNCSTPTATSDSQVDGDCVALDRDAQPAAAGP", "length": 786, "header": "tr|A0A8V0YAM6-1|A0A8V0YAM6_CHICK Isoform 1 of Major facilitator superfamily domain containing 6 OS=Gallus gallus OX=9031 GN=MFSD6 PE=1 SV=1 CANONICAL=A0A8V0YAM6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6/entry#A0A8V0YAM6-1", "sequence": { "sequence": "MAADDKVAILTDDEEEQKRKYVLADPFNGISKDQDLHPQNESPSTETTTVPDEELDWLEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVRPATLRCVPKGLPPAHPTNASSLLTTISQNTSVSSPLTAISTVSPKVRGKRDLLTSRPVTLGVTGTAAPEVTFLLPTQSGNVEFALENSTHFLLKNTTVTASPGNVTPSTTTLSATTTKPVPSDQAVLVYDQQEVEAIFLLILLVVITGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIEVAIEGQGCKAPEYKNYRIVFIVFGVLMTMALIVATQFRFHYTHFKQDENKRKEVEISQVDRNASNESSDNTPTTSMSQSQSFSFWDLIKLLCSIQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELVGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMVGGVLVNYFGPAATFRGIGMACLVILLLFALIQWLLVPDEEEEKTMLAERIPVPSSPVPIATIDLVQQQSEDVMPRTEPRLPLKKTKHQEEQEDVNKPAWGVSSSPWVTLAYAIYQIKEMVKLSKTHPLPENQPLQKISENCSALASSERQPPTATDSGQPRNCSTPTATSDSQVDGDCVALDRDAQPAAAGP", "length": 786, "header": "tr|A0A8V0YAM6-1|A0A8V0YAM6_CHICK Isoform 1 of Major facilitator superfamily domain containing 6 OS=Gallus gallus OX=9031 GN=MFSD6 PE=1 SV=1 CANONICAL=A0A8V0YAM6-1" }, "locus": { "chromosome": "7", "start_pos": 221970, "end_pos": 204565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030693.1", "url": "https://www.ensembl.org/id/ENSGALT00010030693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017798.1", "url": "https://www.ensembl.org/id/ENSGALP00010017798.1" } ] } }, { "isoform_ac": "A0A8V0YJ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6/entry#A0A8V0YJ09-1", "sequence": { "sequence": "MAADDKVAILTDDEEEQKRKYVLADPFNGISKDQDLHPQNESPSTETTTVPDEELDWLEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVRPATLRCVPKGLPPAHPTNASSLLTTISQNTSVSSPLTAISTVSPKVRGKRDLLTSRPVTLGVTGTAAPEVTFLLPTQSGNVEFALENSTHFLLKNTTVTASPGNVTPSTTTLSATTTKPVPSDQAVLVYDQQEVEAIFLLILLVVITGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIEVAIEGQGCKAPEYKNYRIVFIVFGVLMTMALIVATQFRFHYTHFKQDENKRKEVEISQVDRNASNESSDNTPTTSMSQSQSFSFWDLIKLLCSIQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELVGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGPAATFRGIGMACLVILLLFALIQWLLVPDEEEEKTMLAERIPVPSSPVPIATIDLVQQQSEDVMPRTEPRLPLKKTKHQEEQEDVNKPAWGVSSSPWVTLAYAIYQIKEMVKLSKTHPLPENQPLQKISENCSALASSERQPPTATDSGQPRNCSTPTATSDSQVDGDCVALDRDAQPAAAGP", "length": 732, "header": "tr|A0A8V0YJ09-1|A0A8V0YAM6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 6 OS=Gallus gallus OX=9031 GN=MFSD6 PE=1 SV=1 CANONICAL=A0A8V0YAM6-1" }, "locus": { "chromosome": "7", "start_pos": 221970, "end_pos": 204565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030695.1", "url": "https://www.ensembl.org/id/ENSGALT00010030695.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017801.1", "url": "https://www.ensembl.org/id/ENSGALP00010017801.1" } ] } }, { "isoform_ac": "A0A8V0YNT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6/entry#A0A8V0YNT3-1", "sequence": { "sequence": "MAADDKVAILTDDEEEQKRKYVLADPFNGISKDQDLHPQNESPSTETTTVPDEELDWLEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVRPATLRCVPKGLPPAHPTNASSLLTTISQNTSVSSPLTAISTVSPKVRGKRDLLTSRPVTLGVTGTAAPEVTFLLPTQSGNVEFALENSTHFLLKNTTVTASPGNVTPSTTTLSATTTKPVPSDQAVLVYDQQEVEAIFLLILLVVITGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIEVAIEGQGCKAPEYKNYRIVFIVFGVLMTMALIVATQFRFHYTHFKQDENKRKEVEISQVDRNASNESSDNTPTTSMSQSQSFSFWDLIKLLCSIQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELVGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMVGGVLVNYFGPAATFRGIGMACLVILLLFALIQWLLVPDEEEEKTMLAERIPVPSSPVPIATIDLVQQQSEDVMPRTEPRLPLKKTKHQEEQEDVNKPAWGVSSSPWVTLAYAIYQIKEMVKLSKTHPLPENQPLQLGKEMEENQ", "length": 738, "header": "tr|A0A8V0YNT3-1|A0A8V0YAM6_CHICK Computationally mapped isoform of Major facilitator superfamily domain containing 6 OS=Gallus gallus OX=9031 GN=MFSD6 PE=1 SV=1 CANONICAL=A0A8V0YAM6-1" }, "locus": { "chromosome": "7", "start_pos": 221970, "end_pos": 204728, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030689.1", "url": "https://www.ensembl.org/id/ENSGALT00010030689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017794.1", "url": "https://www.ensembl.org/id/ENSGALP00010017794.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 260, "start_aa": "Thr", "end_pos": 260, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr260", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423978", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LNG3-1", "protein_name": "Major facilitator superfamily domain containing 6", "gene_name": "MFSD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATDDKVAILTDDEEEQKRKYVLADPFNGISREPEPPSNETPSPSETAAIPEEEIDWIEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVKPATLRCVPKIPPTVHPTNSSHPFTILPTNSSIVSFITTSPRIRDKRQLLPYGGPVMSEVGPNVTETVIFSTAPNKTSAPTLQTQTDEIIDHIVTLNSSTATSSTPPGNSARETTTSMVTTTKSVPSDRVTLVYDQQEVEAIFLVVLVVVVIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHVDVLIEGKGCKPPEYRNYQIVFFVFGVLMTMALIVATQFRFRYSHFKNSESKGKEVEIPQVERNNSTESSEETPTATSHSQAFSFWDLIRLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNFFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPRTEPRLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFAYALYQIKELMQLTRDSRASEIQPLQGTSENQKTSAAGGAQPGPCEAPPDPPRSQPSPPAAASQTQSSPAHPSVDPRAEDSEDHQAPPAAGGH", "length": 799 }, "evidence": [ { "id": "A0A8V0YAM6", "url": "https://omabrowser.org/oma/group/A0A8V0YAM6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A4X1TE34-1", "protein_name": "Major facilitator superfamily domain-containing protein 6", "gene_name": "MFSD6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATDDKVAILTDDEEEQKRKYVLADPFNGISREPEPPSNETPSPSESAAIPEEETDWIEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKVVLLFSLLCWVLFNLGIGFVKPATLRCVPKIPPTARPTNSSHPFTILPANSSIVPSITTSTRTREKRNLPPYDGLEMLVSEPNVTETVIFSTAPNKTSAPTLQPQTDEITDRVMDLTSHPSTAPSTPPGNTTRETTTSLVTTTKSLPSDQVTLVYDQQEVEAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIDVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFKNGENKGKEVEIPQVERNSSTECSEETPTTTSHSQAFNFWDLIRLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPRIEPRLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFVYALYQIKEMMQLTRDNRASEIQPLQLHIGKEMKGDQ", "length": 744 }, "evidence": [ { "id": "A0A8V0YAM6", "url": "https://omabrowser.org/oma/group/A0A8V0YAM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZCJ3-1", "protein_name": "Major facilitator superfamily domain-containing protein 6", "gene_name": "Mfsd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADDKVAILTDDEEEQKRKYVLADPFNGICRESEPPSNETPSSTETSAIPEEEIDWIEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVKPATLRCIPKIPPTAHPTNVSHPVTILPMNSSTVAFFTTPPKSLEKRSLLFSATEPNISNIDLLSTALTLTTEPTLRPQTEGITHHVTDLILNTSTVTLPPTGNVTRETTIAVVTTTKSLPSDQVTLVYDQQEVEAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIDVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFNNSDGKGKEMEIPQVERDNSTESSEETPTAATHSQAFNFWDLIKLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPHIEARLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFVYALYQVKELMRLTRDSRASEIQPLQGIHENRQVSPAGGAQCAPHETHSDSPRNQLSPDTAASQMQSSPAHPSATPHGQESGQQQTQPTVGEH", "length": 794 }, "evidence": [ { "id": "A0A8V0YAM6", "url": "https://omabrowser.org/oma/group/A0A8V0YAM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LUQ4-1", "protein_name": "Major facilitator superfamily domain-containing protein 6-A", "gene_name": "mfsd6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADDRVAILTEDEEELKRKHLERFDRLSLEIQSPSQPPENDVPNDTAPTPSPQHELSCCERLFLRVNRHLLVSKVFYLFFYAAYGSLHPLLALYYKQLGMNPTQSGLLVGIRYFIEFCSAPFWGIVADRYRKGKAVLLFSMLCWILFNAGIGIVKPPIMACKEETIPTTTKVPTVHPTPSNETFFPNTSSTSQMRRRRDLIGQYPWRTILSSGQSSGYISEHRIKRDSNLSFTPAPEELANTTQTNQTSTTTQPKPSTSISTSTPSSTNTTSSSTTKSTTTNPNLPPPEYNMDQVNAIFLLILLVIIIGEFFSAPAITIVDTVTLHYLGPHRDRYGLQRMWGSLGWGLAMLCIGIWIDHTSTNLIIGNMECIMKNYKNYHIAFIVFGVLMVIALIVATQFKFDVQHHDTNEGQEVGNQQENVQPRGSPGTRSTDTPTIVQAEEFHFWDLMRLLCGVQYSTVLFVAWFMGFGYGFVFTFLYWHLQDLTGTTTLFGICSVLSHVSELAAYFTSHKFIELVGHIRVLYIGLACNTARYLYISYLENAWTVLPMEVLQGITHASVWAACISYLSAAVPPPLRTSAQGILQGLHLGLGRGCGAMVGGIFVNYFGVAETFRGIGMASLVILLIFSLIMYITGQNEKKEDKMLAENIPIPSSPVPIATIDLVQNTADVAAPARPEPKLPARKTQHQQEQEDLNKPAWVPSGSPWVSVALLVYQIREMVLLAKARPTVEVQPLQGTDEVRSDSQEDQSPPVFSDAVQNENTPSGLQDHSGSPTAQLDVPTRDTQPPSQHIS", "length": 793 }, "evidence": [ { "id": "A0A8V0YAM6", "url": "https://omabrowser.org/oma/group/A0A8V0YAM6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZSS7-1", "protein_name": "Major facilitator superfamily domain-containing protein 6", "gene_name": "MFSD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADDKVAILTDDEEEQKRKYVLADPFNGISREPEPPSNETPSSTETSAIPEEEIDWIEKHCVKINNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFKKGKIVLLFSLLCWVLFNLGIGFVKPATLRCVPKIRPTTHPTNASHQLTILPTNSSFTSFLTISPKMREKRNLLETRLNVSDTVTLPTAPNMNSEPTLQPQTGEITNRMMDLTLNSSTATPVSPGSVTKETTTVIVTTTKSLPSDQVMLVYDQQEVEAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIEVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFKNDDSKGKEVEIPQVERNNSTESSEETPTTTSHSQAFNFWDLIKLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPRIEPRLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFVYALYQIKEMMQLTRDNRASEIQPLQGTNENRENSPAGRAQPVPCETHSDPSRNQPSPDAAASQTQTSPAHPSVDPCTEESEEQQAQLAAGGH", "length": 791 }, "evidence": [ { "id": "A0A8V0YAM6", "url": "https://omabrowser.org/oma/group/A0A8V0YAM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CBH5-1", "protein_name": "Major facilitator superfamily domain-containing protein 6", "gene_name": "Mfsd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADDKVAILTDDEEEQKRKYVLADPFNGICREPEPPSNETPSSTETSAIPEEEIDWIEKHCVKVNNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGVVADRFRKGKIVLLFSLLCWVLFNLGIGFVKPATLRCLPKIPPTAHPTNVSHPVTVLPMNSSTVAFFSTPPKLLQKRDVQLSETEPNISDIDLVSTALTLTSEPTRRPQTEAITHPVTGLILNTSTVTLPPTGNVTRETTIAVVTTTKSLPSDQVTLVYDQQEVEAIFLIILVVVIIGEFFSASSVTIVDTVTLQYLGKHRDRYGLQRMWGSLGWGLAMLSVGIGIDYTHIDVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFNNSDGKGKEVEIPQVERDNSTESSEETPTAATHSQAFNFWDLIKLLCSVQYGSVLFVAWFMGFGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLACNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLHLGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAVPDEEEDKTMLAERIPVPSSPVPIATIDLVQQQTEDVMPRVEARLPPKKTKHQEEQEDVNKPAWGVSSSPWVTFVYALYQVKELIQLTRESRASEIQPLQVTLCWASVASAPLLPPCSSKHMGNRKTGMLAKDISGLRSLCHSVYQVA", "length": 775 }, "evidence": [ { "id": "A0A8V0YAM6", "url": "https://omabrowser.org/oma/group/A0A8V0YAM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "antigen processing and presentation of exogenous peptide antigen via MHC class I", "id": "GO:0042590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042590", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM6" }, { "id": "PF12832", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12832" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily associated", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 609, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 260 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 756, "end_pos": 758 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAM8-1", "uniprot_ac": "A0A8V0YAM8", "uniprot_id": "A0A8V0YAM8_CHICK", "mass": { "chemical_mass": 121746.0, "monoisotopic_mass": 121746.0 }, "refseq": { "ac": "XP_004936221", "name": "zinc finger protein 518B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936221" }, "gene_names": [ { "name": "ZNF518B", "type": "recommended", "evidence": [ { "id": "A0A8V0YAM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8" } ] }, { "name": "ZNF518B", "type": "synonym", "evidence": [ { "id": "XP_004936221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936221" } ] } ], "protein_names": [ { "name": "Zinc finger protein 518B", "type": "synonym", "evidence": [ { "id": "A0A8V0YAM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 518B", "type": "synonym", "evidence": [ { "id": "XP_004936221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936221" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004936221.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936221" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF518B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8", "locus": { "chromosome": "4", "start_pos": 77430184, "end_pos": 77811949, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009441", "url": "https://www.ensembl.org/id/ENSGALG00010009441" } ] } } ], "crossref": [ { "id": "422841", "url": "https://www.ncbi.nlm.nih.gov/gene/422841", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422841", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422841", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEYGAVR", "url": "https://omabrowser.org/oma/group/CEYGAVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAM8", "url": "https://www.orthodb.org/?gene=A0A8V0YAM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004936221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936221", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLKKMREILPRLYPGQVNDKNNSLTTSPKQSFEDKSNPSNGDDDQNYCYQGTEAENNKLSLISCMKCRNIQKISKQDLEKHKKLGWAEDKNFICKMCSHITSPAFHFVPEGANAIDFEKHEKTYQRKKQKAFKVKNFLPGKYYCDKCRFSTKDPLQYKKHVSQHEEIKFICSYCNYISYTKGEFQRHLVKHTGTFPYQCEYCDYGAVRHDYIVKHTRRVHEAPKKRLSNTGIKRQQKKSCLPSQSTLFEKQKYEEITFQNELSNSSSNITCEIPDKATKIVSSSHDIECSISAASIQNKTILEPSEISMCENQSVEVEVYSPKMEPLQPGMPLTVIAPSELVVPSNCLAQIVEIKIVNGAQQLVLKLIPMKEAACRPVNCAALGLENQGTERTAEGKKPSVSSNELLTMEVNVDKLSSISNQLNLDSKYDKNSDYLYSSDSQYSDCNSVSIQKEDSSKLRLHLVKGIDVRSGVIELCSQSLVTNSTEKKCDLKSPKREADGKNNLHYDLYCYEEGVNTSRPKTAAVSEDKSSKNNSVKTTQGSKNFYSSAVLKQKDVFPLKRDDKECRSPIVNSAETPLAAKGFDRKPVICSEAEKNFHVTKTSPWEDMTFSFSKVKKAETVSQKNNLLLESLELQKMENKNNPFEGPVISSVFSLSSGAANVPESIRWDDTTRNKKSTTLLCRKIAQLMSAAESNMKSMPLRCQASSKKMHFPQENSASCATGLEQAMSFPQVHDGSNVIGSNEHSNEQLLTFARTSKSRVTKNSNVASPVFIPKGTVLRVLNAASSQNSRGIEKMSEASAPSAYCNEMLLPRPVPVSVSEKLSSNLPCLPNQSDPHTQSRNISLRQRPKREMNAKTSSKRTVVPYQKNGDVSKQSKHYSKSQQGPKNKVKQVGYRELPKRKTRTQSETSSGSDMSYLLTARRLRLVPLRMNQLIKCPRRNQPVVVLNHPDVDTPEIINVMKTINKYKGHVLKVVLSERTSSCLGVKRYRKRLTLQNAETGSQAKKQSMLKMKLKKTHKNNYQVVEASPAEPLQCMFKCWFCGRVYADQEEWISHGQRHLIEATKGWDVLSLPVTKH", "length": 1079, "header": "tr|A0A8V0YAM8-1|A0A8V0YAM8_CHICK Isoform 1 of Zinc finger protein 518B OS=Gallus gallus OX=9031 GN=ZNF518B PE=4 SV=1 CANONICAL=A0A8V0YAM8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8/entry#A0A8V0YAM8-1", "sequence": { "sequence": "MQLKKMREILPRLYPGQVNDKNNSLTTSPKQSFEDKSNPSNGDDDQNYCYQGTEAENNKLSLISCMKCRNIQKISKQDLEKHKKLGWAEDKNFICKMCSHITSPAFHFVPEGANAIDFEKHEKTYQRKKQKAFKVKNFLPGKYYCDKCRFSTKDPLQYKKHVSQHEEIKFICSYCNYISYTKGEFQRHLVKHTGTFPYQCEYCDYGAVRHDYIVKHTRRVHEAPKKRLSNTGIKRQQKKSCLPSQSTLFEKQKYEEITFQNELSNSSSNITCEIPDKATKIVSSSHDIECSISAASIQNKTILEPSEISMCENQSVEVEVYSPKMEPLQPGMPLTVIAPSELVVPSNCLAQIVEIKIVNGAQQLVLKLIPMKEAACRPVNCAALGLENQGTERTAEGKKPSVSSNELLTMEVNVDKLSSISNQLNLDSKYDKNSDYLYSSDSQYSDCNSVSIQKEDSSKLRLHLVKGIDVRSGVIELCSQSLVTNSTEKKCDLKSPKREADGKNNLHYDLYCYEEGVNTSRPKTAAVSEDKSSKNNSVKTTQGSKNFYSSAVLKQKDVFPLKRDDKECRSPIVNSAETPLAAKGFDRKPVICSEAEKNFHVTKTSPWEDMTFSFSKVKKAETVSQKNNLLLESLELQKMENKNNPFEGPVISSVFSLSSGAANVPESIRWDDTTRNKKSTTLLCRKIAQLMSAAESNMKSMPLRCQASSKKMHFPQENSASCATGLEQAMSFPQVHDGSNVIGSNEHSNEQLLTFARTSKSRVTKNSNVASPVFIPKGTVLRVLNAASSQNSRGIEKMSEASAPSAYCNEMLLPRPVPVSVSEKLSSNLPCLPNQSDPHTQSRNISLRQRPKREMNAKTSSKRTVVPYQKNGDVSKQSKHYSKSQQGPKNKVKQVGYRELPKRKTRTQSETSSGSDMSYLLTARRLRLVPLRMNQLIKCPRRNQPVVVLNHPDVDTPEIINVMKTINKYKGHVLKVVLSERTSSCLGVKRYRKRLTLQNAETGSQAKKQSMLKMKLKKTHKNNYQVVEASPAEPLQCMFKCWFCGRVYADQEEWISHGQRHLIEATKGWDVLSLPVTKH", "length": 1079, "header": "tr|A0A8V0YAM8-1|A0A8V0YAM8_CHICK Isoform 1 of Zinc finger protein 518B OS=Gallus gallus OX=9031 GN=ZNF518B PE=4 SV=1 CANONICAL=A0A8V0YAM8-1" }, "locus": { "chromosome": "4", "start_pos": 77579682, "end_pos": 77579622, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022560.1", "url": "https://www.ensembl.org/id/ENSGALT00010022560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013003.1", "url": "https://www.ensembl.org/id/ENSGALP00010013003.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422841", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422841", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M9T7-1", "protein_name": "Zinc finger protein 518B", "gene_name": "ZNF518B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKDIGQQLYSTPVGDGRNALTMSPKQPNAHRGTRPDRPDAQTVLYQGSEAESAAMTIATCVKCKSVHEVPLQDLKKGTGQSQKEDKYVCFRCNLGAASPHFHFVNNSRSATQVGNKPEAISSSVNHKFKVRNFKPGKYYCDKCRFSTKDPLQYKKHTLQHEEIKFVCSHCGCISYTKGEFQRHLVKHTGVFPYRCEYCDYGAIRNDYIVKHRRRVHEKTGAKRPPKAIARLEPKRISASKQNPELSKTSSPRTAFQNKLSDQLSRFSPHASKDRTHSVTLLPESKDYQKDVVCIPHKGALSEPTEVINLLENKSVEVEVLSPSKEPVQPGMPLTVVAPAELVVPANCLAQLMDVKVVNGTQQLVLKLFPLEETNSLDAGGGDGGSSERGSKERGASEQEKMASTECTQPLAIEGTVGKLAGIGSLQSSVQKPLKNVKWVRSYDFFMPNSGRHSSGESLLNPGRVESLQKKGYTYPHRAALPSIAFKGHSPLSLVKNGVLRSLGASSNSFPYKAALSFAEDRRNLPSDPQQLFPVSAPPATISFSGEKDSLPLCQNDLGSRNEISLPAKTVTPPRKLQDNQTQEYKAVSNAGQVSSQHRSEYLHINIMGEDRVRAQQSGDKPLELKNPDQTNDPFDGPVISSVFSLSSGSENVPEGVKWNSSTSKIKSIELLRRKIAQLIESCGKPSSLAANSTHRHSAGKASKVTSKSTPEGIQEINVSFTSAGYSTGTLPRPQDAGGISEQLAHQQAYPQLVEGSSGKTESRVTKKPHVATPVLIPKGAVLRVLNSSEDSQIIEATCEAPVNITCTETQLIKPIPLCPMKRTDPDVQFLTSESGPIDMSPNHDLSFRPKSRKESAHCSTMPKKPGSMHGPQGSSEMIKQAKLFPRSLPISKNKPRQISSSKKKSKIQTDPSRCFRDPSIFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVSNVMKVINKYKGNVLKVVLSERTRCQLGMRRHHVRLTYQNAEEANQIKRQMMLKMKLKKVHKNNYQVVDSLPDDSSQCIFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "length": 1078 }, "evidence": [ { "id": "A0A8V0YAM8", "url": "https://omabrowser.org/oma/group/A0A8V0YAM8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2LQ95-1", "protein_name": "Zinc finger protein 518B", "gene_name": "Znf518b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQIKMKDIGEQLYTTQVNGGPSSLTMSPKQPNCNRATRLDRQEAQTLLYQGSEAEAATMTIATCVQCKSVHKIPPQDLRKGPGQSQKEGAYVCFKCSLRTVPAQLHFVNSNPGAVQVRNETEAISSPMNNKFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTMQHEEIKFICSHCSYISYTKGEFQRHLVKHTGVFPYRCEYCEYGAIRNDYIVKHRRRVHERAGAKRPLKTVAKLEPKRTTNTSKQSMELSKAPSPRAAFQNKLSDQLSRFSLHTNKDKTHSLMLLPELKKYQKDVVCIPNKIALSEPSKVSLWGNKNVEVEVLSPSKEPVQPGMPLTVVAPSELVVPTNCLAQLIDVKVVNGTQQLVLKLFPLEENSRLETGRDGGTSECTTTEKGSGGQKKTLSPEAVKSLTMEGSTGEFVGIDHLHSLVQKQLKNVKWVKSCNFLMPNSGVHSHQESFLSSDTIKDLQKTHSLCPPRALPSVALKGHSPASVQNIVSCGPGTTANPFLSKSAVSFAEDGRGTRCDSQQLLPLASLPTKVSFSGEKSLLPIGENDLEARNRISCPETMVSADRKLEDKQIENKAVGNTGQLSSAQKNEYLHINLMGEEKLRSQQPGDQPVQPKNSEKTGNTFEGPVISSVFSLSSGSENVPEGIKWNSSTTKIKSIELLRRKIAQLIESCGKPSSLSANGAQRRSIGQAPKLTSKAIPKGIQEMSVSLPGPGPSSGASIGPLQKPQNEGSVTSNGQLAQRQICPKFVSADDGNMESRVTRKTPVATPVLIPKGAVLRVLNSSEDAHIIEATYDTPVSIPCNEAQLAEPLPFCPVTGSGSQPLTCRRGPADMSPNLETSLRPKSKREDSVCTTTPKKIIPVYSTQPGNNDSSRPGRPISRNLTISKNKTKQVISAKKKNKMQADPIRSLKDPSFFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRYQLGVRRHYMRLTYQNSEEANHLKRQMMLKMKLKKVHKNNYQVVGSLPDDPAQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "length": 1083 }, "evidence": [ { "id": "A0A8V0YAM8", "url": "https://omabrowser.org/oma/group/A0A8V0YAM8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2RRE4-1", "protein_name": "Zinc finger protein 518B", "gene_name": "Znf518b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDIGEQLYTTQVNGGPSSLTMSPKQPNRATRTERQEAQTLLYQGSEAEAATMTIATCVQCKSVHKIPTQDLRKGPGQSQDTYVCFKCSLRAVPTQLHFVNNNAGAAHVRNETETISSPVNKFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQHEEIRFICSHCSYISYTKGEFQRHLVKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHERAGAKRPFKTVAKLEPKRTSIPKQSMELSKGPSPRAAFQNKLSDQLSRFSLHANKDKTHNLMLLPELKKYQKDVVCIPNKVTLSEPREVSLLGNKNVEVEVLSPSKEPVHPGMPLTVMAPSELVVPTNCLAQLMDVKVVNGAQQLVLKLFPLEENARLETSRGDGGTSECLSTEKGSGGQKKMLSPEASRSLAVEGNAGDFVGLDRLHSLVQKQLKNVKWVKSCNFFMPNSGVHSQQESFLGSDTIKELQKSHSLCPPRALPSAAIKSHSPASVQNSVPYGPGATVSHFLSKAAVAFADDRRGARSNSQQLLPLASLPSKVPFSGEKGLLPIGESDLEARNRISRPETLVSSDRKLEDKQMESKAVGNTGQVSSVQNKEYLHINITGEDKPRSQQPGDQPGQPKTSETAGATFEGPIISSVFSLSSGSENVPEAIKWNSSTTKIKSIELLRRKIAQLIESCGKPSSLSANSAQRRSIGQAPKLTSKATPKAIQEMSVSLTGPGPTPGPSVGPLQKPPNEDSITGSRQLVPQQVCPQFISANDGKMENRVTRKTPVATPVLIPKGAVLRVLNSSEDAHIIEATCDTPVSIPCSEAQLAGTLPFCPMKQTGSGSQPLTCRSGPADMSPGLETSLRPKSRKEDTICSATAKKMVPVYSTAPGSSDSIRQGRPVSRNLTVSKNKTKQVNSTKKKNKMQANPGRYFKDPPSFFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGVRRYHMRLTYQNVAETNHMKRQMMLKMKLKKVHKNNYQVVGSMPDDPAQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "length": 1077 }, "evidence": [ { "id": "A0A8V0YAM8", "url": "https://omabrowser.org/oma/group/A0A8V0YAM8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ABC6-1", "protein_name": "Zinc finger protein 518B", "gene_name": "Zfp518b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLREMKDIGEQLYTTQVNGGPSSLTMSPKQPNRATRPERQEAQTLLYQGSEAEAATMTIATCVQCKSIHKIPTQDLRKGPGQGQDTYVCFKCSLRAVPTQLHFVNNNAGAAHIRNETETISSPVNKFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQHEEIKFICSHCSYISYTKGEFQRHLVKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHERAGAKRPFKTVAKLEPKRTNISKQSMELSKAPSPRAAFQNKLSDQLSRFSLHASKDKTHNMMLLPELKKYQKDVVCIPNKVTLCEPREVSLLGNKNVEVEVLSPSKEPVQPGLPLTVMAPSELVVPTNCLAQLMDVKVVNGTQQLVLKLFPLEENSRLETSRGDGGVSECTTTEKGSGGQTKVLSTEASRSLAMEGNAGEFVGLDRLHSLVQKQLKNVKWVKSCNFFMPNSGIHSHQDSFLGPDTIKDLQKSHSLCPPRALPSASVKSHSPASVQSSVSYGPGATVSRFLTKAAAAFAEDGRGSRSDSQQLLPLASLSSKVSFSGEKGLLPLGENDLEARNRTSRPETVVSSDRKLEDKPMESKAVGSTSQVSSVQKKEYLHINFAGEDKTRSQQPGGRPVLPKTSETAGNAFEGPIISSVFSLSSGSENVPEGIKWNSSTTKIKSIELLRRKIAQLIESCGKPSSLSAGSPQRRPIGQAPKLTSKATPKAIQEMSGSLTGPGPSVGPLQKPQNEDSITGSGQHAPQQMCPPFVSANDGKTESRVTRKTPVATPVLIPKGAVLRVLNSSEDARIIEATCDTPVSIPCSEAQLAGTLPFCPVKQPGSGSQLLPCRSGPADLSPSLETSLRPKSRKEDPICSVTPKKIIPVYSTVPGSSDSSRQGRPVSRNLTVSKNKTKQVSSAKKKNKMQANPSRYFKDPSFFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGVRRYHMRLTYQNVAETNHMKRQMMLKMKLKKVHKNNYQVVGSLPDDPAQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "length": 1077 }, "evidence": [ { "id": "A0A8V0YAM8", "url": "https://omabrowser.org/oma/group/A0A8V0YAM8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LE67-1", "protein_name": "Zinc finger protein 518B", "gene_name": "ZNF518B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQIKKMKDIGQQLYSPQVSDGRTSLTMSPKQPNANRATRPDGQDAPTVLYQGSEAEAAAVTVATCAKCRSVHEIPLQELKKGAGQSQKEDKYICFKCSLGAAPPQFHFLNSNRGAAHVGDRTESVSSSVGNKFKVRNFKPGKYYCDKCRFSTKDPLQYKKHTLQHEEIKFICSHCSYISYTKGEFQRHLVKHTGIFPYQCEYCDYGAIRNDYIVKHRKRVHEKAGGKRLPKTVTKLEPKRVGAAKPHPELFKAPGPRTAFQNKLSDQLSRFSLHAHKDRTHNIMLLPESKEPQKDVVCVPNRATPSGPSDVGLLENKSVEVEVLSPAKEPVQPGMPLTVVAPAELVVPANCLAQLIDVKVVNGTQQLVLKLFPLEENSRLDAGGGDGGPCQRAARERGSKEHDEMVSGGDQTKSLTVAGDVGRLAGIDELHASVQKQLKNVKWVRSYDFFMSNSSTHGAGELLLNPGGVEELQKRRYMYPHRTALPSAAFRGHSPSSLVRSSLLSGLGAAASAFPYKAAVSFPDAGRRVRGDSRHLFPLAAASAAISFSGEKDLPPARKNDLEARGAISIPVKMVPPNRKPRENQAQDPRAVSDVGPVSPQPKGEYLHINITGEERLRPPQPGEKPLELKNPERTQDPFDGPVISSVFSLSSGSENVPEGVKWNSSTSKIKSIELLRRKIAQLIESCGKPSPPAASGAHRRSVGKAAKGAAAAAADGIREISVSFAGPGFPTGAVPRPQGEGGAGGDGQPAPRQVYPQVVEGGSGRAEGRGARKPQGAPPVLLPKGAVLRFLNSSEDSRVIEATCEAPVSLSGSETHVARPVPFRPGKQTDAESRALPGESGLADTCPGLDLAPRPKPRRESADGGSAPRRPGPPHGPQGSGEVSKQGRLFSRSLPVSKSKPRHVNSSKKKSKMQADPSRYFRDPSIFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVSNVMKVINKYKGNVLKVVLSERTRCQLGIRRHHVRLTYQNAEEANQVKRQMMLKMKLKKVHKNNYQVVDSLPDDSSQCIFKCWFCGRLYEDQEEWMSHGQRHLIEATRGWDALSSKGK", "length": 1085 }, "evidence": [ { "id": "A0A8V0YAM8", "url": "https://omabrowser.org/oma/group/A0A8V0YAM8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9C0D4-1", "protein_name": "Zinc finger protein 518B", "gene_name": "ZNF518B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDIGQQLYTTHLNGGHNSLTMSPKQPDANGAPRPNRQEAQTLLYQGSEAEAAMMTIATCAKCKSVHKISLQDLQKGTGKDGMYVCFQCSLGAAPPNFHFVSNNSSATHVGNKTENFSSSVNSKFKVRNFKPGKYYCDKCRFSTKDPLQYKKHTLQHEEIKFICSHCSYISYTKGEFQRHLVKHTGIFPYQCEYCDYGAIRNDYIVKHTKRVHERAGAKRPVKAVAKLEPKRTGTSKQNPELLKASNPRTTFQNKWSDQLSGFSLHANKDKMHNIMLLPEPKEYQKDVVCIPNKMTLSEPNEVNLFENKNVEVEVLSPAKEPVQPGMPLTVVAPAELVVPANCLAQLIDVKVVNGTQQLVLKLFPLEENNCLEAGRDNGGNSERMVKEKGSNEQEKVLSAEKTKSLTVDGNVGKLVGIDSFQPSVQKQLKNVKWVRSYDFIMPNSSVHNNGKSFINSETIEDFQKKNNLYPHRTAFPSVALKGHSLASVFKNSVLRSLGAASNPFPYKAAVCFAESGRNLHSSSQQLLPFAASPATCSFSGEKGLLPVSENDLESTSKVNIPVKVVSSNRKQEDNQTEEHKAVSTVGQISSQHKSEYLHINITGEDRSQQPGDKPLELKNSERTNNTNDGPVISSVFSLSSGSENVPEGIKWNSSTSKIKSIELLRRKIAQLIESCGKPSSLASNSAHRRSVGQASKGTSKATSEGIQEINVSLTGLGHSTGTLQKPPNDGGITGNRQLTHQQIYPHFADGSNRKTKSRVARKAHVATPVLIPKGAVLRVLNSSENAHIIEATCEAPVSIPCSERQLIKPVPFCPVRQADSDLQPLRSERGPIDMSPNIETPLRPKLRKESAVCSTIHRKTGLLYGQQGSSELNKQGRLLSRSLSISRNKTKQVHLSRKKNKIQAEPSRCLKDPSIFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGIRRHHVRLTYQNAEEASQIKRQMMLKMKLKKVHKNNYQVVDSLPDDSSQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK", "length": 1074 }, "evidence": [ { "id": "A0A8V0YAM8", "url": "https://omabrowser.org/oma/group/A0A8V0YAM8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 834, "end_pos": 836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 197, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 834, "end_pos": 836 }, { "start_pos": 844, "end_pos": 846 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAM9-1", "uniprot_ac": "A0A8V0YAM9", "uniprot_id": "A0A8V0YAM9_CHICK", "mass": { "chemical_mass": 81134.0, "monoisotopic_mass": 81134.0 }, "refseq": {}, "gene_names": [ { "name": "TBC1D15", "type": "recommended", "evidence": [ { "id": "A0A8V0YAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 15", "type": "recommended", "evidence": [ { "id": "A0A8V0YAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9/entry#names_and_taxonomy" } ] }, { "name": "GTPase-activating protein RAB7", "type": "synonym", "evidence": [ { "id": "A0A8V0YAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a GTPase activating protein for RAB7A. Does not act on RAB4, RAB5 or RAB6.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ5#function" }, { "database": "UniProtKB", "id": "ARBA00055283", "url": "https://www.uniprot.org/uniprotkb/ARBA00055283#function" }, { "database": "UniProtKB", "id": "A0A8V0YJ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ00#function" }, { "database": "UniProtKB", "id": "A0A8V0YJ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ14#function" }, { "database": "UniProtKB", "id": "A0A8V0YNU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU2#function" }, { "database": "UniProtKB", "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBC1D15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9", "locus": { "chromosome": "1", "start_pos": 36610318, "end_pos": 36583070, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012778", "url": "https://www.ensembl.org/id/ENSGALG00010012778" } ] } } ], "crossref": [ { "id": "A0A8V0YAM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAM9", "url": "https://www.orthodb.org/?gene=A0A8V0YAM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGZ5", "url": "https://www.orthodb.org/?gene=A0A8V0YGZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ00", "url": "https://www.orthodb.org/?gene=A0A8V0YJ00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ14", "url": "https://www.orthodb.org/?gene=A0A8V0YJ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YNU2", "url": "https://www.orthodb.org/?gene=A0A8V0YNU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YNU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSALGMKQSSARWNPRAGLSSHVLSALSSSGDGFAREMRISPCGEVLYEQDGVFIHPSCGKNDDQDNFISGVLRVIEKENEVIVDWRPQDDTLDTSNILCAGKDSSSVVEWTPVPKEKSSRGADRPNNYEAEWDMVTTVSFKKKPHSNGDATNHTNGESTWSFLFSLTDLKSIKQNKEGMGWSYLVFCLKDDVKLPALHFHHGDSKLFIKCLENHVVLRESPQDKLILLVNSQNKSLSQSFENLLDEPSYGLLQKWKKDPYTVTMGRFSKVTNYIFDSFRLSDPSTQRRPPSEMADFLNDAIPGLKINQQEEPGFEVITRIDLGEQPEVSRREPVSIEEWTKNMDSEGRILNVDYIKQSIFKGGLCHTLRKEAWKFLLGYFPWNSTKEERANLQKRKTDEYFRMKLQWKSVSEEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGEDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPVLYVMENEVDAFWCFVSYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFQDILRLWEVMWTELPCQNFHLLLCCAILESEKQQIMEKQYGFNEILKHINELSMKIDVEYILCKAEAISMQMMNCKELPQAVSEILGIESSSVTPDSDTGEDESGAVLSCPTSSYQNISTPVIAANGTRESTQQMSETQSLAPA", "length": 705, "header": "tr|A0A8V0YAM9-1|A0A8V0YAM9_CHICK Isoform 1 of TBC1 domain family member 15 OS=Gallus gallus OX=9031 GN=TBC1D15 PE=1 SV=1 CANONICAL=A0A8V0YAM9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9/entry#A0A8V0YAM9-1", "sequence": { "sequence": "MQSALGMKQSSARWNPRAGLSSHVLSALSSSGDGFAREMRISPCGEVLYEQDGVFIHPSCGKNDDQDNFISGVLRVIEKENEVIVDWRPQDDTLDTSNILCAGKDSSSVVEWTPVPKEKSSRGADRPNNYEAEWDMVTTVSFKKKPHSNGDATNHTNGESTWSFLFSLTDLKSIKQNKEGMGWSYLVFCLKDDVKLPALHFHHGDSKLFIKCLENHVVLRESPQDKLILLVNSQNKSLSQSFENLLDEPSYGLLQKWKKDPYTVTMGRFSKVTNYIFDSFRLSDPSTQRRPPSEMADFLNDAIPGLKINQQEEPGFEVITRIDLGEQPEVSRREPVSIEEWTKNMDSEGRILNVDYIKQSIFKGGLCHTLRKEAWKFLLGYFPWNSTKEERANLQKRKTDEYFRMKLQWKSVSEEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGEDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPVLYVMENEVDAFWCFVSYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFQDILRLWEVMWTELPCQNFHLLLCCAILESEKQQIMEKQYGFNEILKHINELSMKIDVEYILCKAEAISMQMMNCKELPQAVSEILGIESSSVTPDSDTGEDESGAVLSCPTSSYQNISTPVIAANGTRESTQQMSETQSLAPA", "length": 705, "header": "tr|A0A8V0YAM9-1|A0A8V0YAM9_CHICK Isoform 1 of TBC1 domain family member 15 OS=Gallus gallus OX=9031 GN=TBC1D15 PE=1 SV=1 CANONICAL=A0A8V0YAM9-1" }, "locus": { "chromosome": "1", "start_pos": 36609143, "end_pos": 36583526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030699.1", "url": "https://www.ensembl.org/id/ENSGALT00010030699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017803.1", "url": "https://www.ensembl.org/id/ENSGALP00010017803.1" } ] } }, { "isoform_ac": "A0A8V0YGZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9/entry#A0A8V0YGZ5-1", "sequence": { "sequence": "MAAPPSGKVLYEQDGVFIHPSCGKNDDQDNFISGVLRVIEKDSSSVVEWTPVPKEKSSRGADRPNNYEAEWDMVTTVSFKKKPHSNGDATNHTNGESTWSFLFSLTDLKSIKQNKEGMGWSYLVFCLKDDVKLPALHFHHGDSKLFIKCLENHVVLRESPQDKLILLVNSQNKSLSQSFENLLDEPSYGLLQKWKKDPYTVTMGRFSKVTNYIFDSFRLSDPSTQRRPPSEMADFLNDAIPGLKINQQEEPGFEVITRIDLGEQPEVSRREPVSIEEWTKNMDSEGRILNVDYIKQSIFKGGLCHTLRKEAWKFLLGYFPWNSTKEERANLQKRKTDEYFRMKLQWKSVSEEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGEDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPVLYVMENEVDAFWCFVSYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFQDILRLWEVMWTELPCQNFHLLLCCAILESEKQQIMEKQYGFNEILKHINELSMKIDVEYILCKAEAISMQMMNCKELPQAVSEILGIESSSVTPDSDTGEDESGAVLSCPTSSYQNISTPVIAANGTRESTQQMSETQSLAPA", "length": 642, "header": "tr|A0A8V0YGZ5-1|A0A8V0YAM9_CHICK Computationally mapped isoform of TBC1 domain family member 15 OS=Gallus gallus OX=9031 GN=TBC1D15 PE=1 SV=1 CANONICAL=A0A8V0YAM9-1" }, "locus": { "chromosome": "1", "start_pos": 36609143, "end_pos": 36583205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030694.1", "url": "https://www.ensembl.org/id/ENSGALT00010030694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017800.1", "url": "https://www.ensembl.org/id/ENSGALP00010017800.1" } ] } }, { "isoform_ac": "A0A8V0YJ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9/entry#A0A8V0YJ00-1", "sequence": { "sequence": "SSVLYEQDGVFIHPSCGKNDDQDNFISGVLRVIEKENEVIVDWRPQDDTLDTSNILCAGKDSSSVVEWTPVPKEKSSRGADRPNNYEAEWDMVTTVSFKKKPHSNGDATNHTNGESTWSFLFSLTDLKSIKQNKEGMGWSYLVFCLKDDVKLPALHFHHGDSKLFIKCLENHVVLRESPQDKLILLVNSQNKSLSQSFENLLDEPSYGLLQKWKKDPYTVTMGRFSKVTNYIFDSFRLSDPSTQRRPPSEMADFLNDAIPGLKINQQEEPGFEVITRIDLGEQPEVSRREPVSIEEWTKNMDSEGRILNVDYIKQSIFKGGLCHTLRKEAWKFLLGYFPWNSTKEERANLQKRKTDEYFRMKLQWKSVSEEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGEDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPVLYVMENEVDAFWCFVSYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFQDILRLWEVMWTELPCQNFHLLLCCAILESEKQQIMEKQYGFNEILKHINELSMKIDVEYILCKAEAISMQMMNCKELPQAVSEILGIESSSVTPDSDTGEDESGAVLSCPTSSYQNISTPVIAANGTRESTQQMSETQSLAPA", "length": 661, "header": "tr|A0A8V0YJ00-1|A0A8V0YAM9_CHICK Computationally mapped isoform of TBC1 domain family member 15 OS=Gallus gallus OX=9031 GN=TBC1D15 PE=1 SV=1 CANONICAL=A0A8V0YAM9-1" }, "locus": { "chromosome": "1", "start_pos": 36609143, "end_pos": 36589381, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030686.1", "url": "https://www.ensembl.org/id/ENSGALT00010030686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017791.1", "url": "https://www.ensembl.org/id/ENSGALP00010017791.1" } ] } }, { "isoform_ac": "A0A8V0YJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9/entry#A0A8V0YJ14-1", "sequence": { "sequence": "MAAPPSGKVLYEQDGVFIHPSCGKNDDQDNFISGVLRVIEKENEVIVDWRPQDDTLDTSNILCAGKDSSSVVEWTPVPKEKSSRGADRPNNYEAEWDMVTTVSFKKKPHSNGGTSKINATNHTNGESTWSFLFSLTDLKSIKQNKEGMGWSYLVFCLKDDVKLPALHFHHGDSKLFIKCLENHVVLRESPQDKLILLVNSQNKSLSQSFENLLDEPSYGLLQKWKKDPYTVTMGRFSKVTNYIFDSFRLSDPSTQRRPPSEMADFLNDAIPGLKINQQEEPGFEVITRIDLGEQPEVSRREPVSIEEWTKNMDSEGRILNVDYIKQSIFKGGLCHTLRKEAWKFLLGYFPWNSTKEERANLQKRKTDEYFRMKLQWKSVSEEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGEDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPVLYVMENEVDAFWCFVSYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFQDILRLWEVMWTELPCQNFHLLLCCAILESEKQQIMEKQYGFNEILKHINELSMKIDVEYILCKAEAISMQMMNCKELPQAVSEILGIESSSVTPDSDTGEDESGAVLSCPTSSYQNISTPVIAANGTRESTQQMSETQSLAPA", "length": 672, "header": "tr|A0A8V0YJ14-1|A0A8V0YAM9_CHICK Computationally mapped isoform of TBC1 domain family member 15 OS=Gallus gallus OX=9031 GN=TBC1D15 PE=1 SV=1 CANONICAL=A0A8V0YAM9-1" }, "locus": { "chromosome": "1", "start_pos": 36609143, "end_pos": 36583205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030705.1", "url": "https://www.ensembl.org/id/ENSGALT00010030705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017806.1", "url": "https://www.ensembl.org/id/ENSGALP00010017806.1" } ] } }, { "isoform_ac": "A0A8V0YNU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9/entry#A0A8V0YNU2-1", "sequence": { "sequence": "MAAPPSGKVLYEQDGVFIHPSCGKNDDQDNFISGVLRVIEKENEVIVDWRPQDDTLDTSNILCAGKDSSSVVEWTPVPKEKSSRGADRPNNYEAEWDMVTTVSFKKKPHSNGDATNHTNGESTWSFLFSLTDLKSIKQNKEGMGWSYLVFCLKDDVKLPALHFHHGDSKLFIKCLENHVVLRESPQDKLILLVNSQNKSLSQSFENLLDEPSYGLLQKWKKDPYTVTMGRFSKVTNYIFDSFRLSDPSTQRRPPSEMADFLNDAIPGLKINQQEEPGFEVITRIDLGEQPEVSRREPVSIEEWTKNMDSEGRILNVDYIKQSIFKGGLCHTLRKEAWKFLLGYFPWNSTKEERANLQKRKTDEYFRMKLQWKSVSEEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGEDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPVLYVMENEVDAFWCFVSYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFQDILRLWEVMWTELPCQNFHLLLCCAILESEKQQIMEKQYGFNEILKELPQAVSEILGIESSSVTPDSDTGEDESGAVLSCPTSSYQNISTPVIAANGTRESTQQMSETQSLAPA", "length": 638, "header": "tr|A0A8V0YNU2-1|A0A8V0YAM9_CHICK Computationally mapped isoform of TBC1 domain family member 15 OS=Gallus gallus OX=9031 GN=TBC1D15 PE=1 SV=1 CANONICAL=A0A8V0YAM9-1" }, "locus": { "chromosome": "1", "start_pos": 36609143, "end_pos": 36583205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030702.1", "url": "https://www.ensembl.org/id/ENSGALT00010030702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017804.1", "url": "https://www.ensembl.org/id/ENSGALP00010017804.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 678, "end_pos": 680, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAM9" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 575, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 678, "end_pos": 680 }, { "start_pos": 687, "end_pos": 689 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAN0-1", "uniprot_ac": "A0A8V0YAN0", "uniprot_id": "A0A8V0YAN0_CHICK", "mass": { "chemical_mass": 47033.0, "monoisotopic_mass": 47033.0 }, "refseq": { "ac": "XP_040518234", "name": "uncharacterized protein C12orf50 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518234" }, "gene_names": [ { "name": "C12orf50", "type": "recommended", "evidence": [ { "id": "A0A8V0YAN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN0" } ] }, { "name": "C12orf50", "type": "synonym", "evidence": [ { "id": "XP_040518234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518234" } ] } ], "protein_names": [ { "name": "Chromosome 12 open reading frame 50", "type": "synonym", "evidence": [ { "id": "A0A8V0YAN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C12orf50 homolog", "type": "synonym", "evidence": [ { "id": "XP_040518234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518234" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040518234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518234" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C12orf50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN0", "locus": { "chromosome": "1", "start_pos": 42833017, "end_pos": 42848173, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011375", "url": "https://www.ensembl.org/id/ENSGALG00010011375" } ] } } ], "crossref": [ { "id": "A0A8V0YAN0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAN0", "database": 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frame 50 OS=Gallus gallus OX=9031 GN=C12orf50 PE=4 SV=1 CANONICAL=A0A8V0YAN0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAN0/entry#A0A8V0YAN0-1", "sequence": { "sequence": "MAEGGNDRYFYSPYAQQNYSNILCFWETQPLGCVRISCVFHHSKPRNINGLFLPPSNNTVFQQEGQGGILNSAHSQESLRIQETFLRPIHPPVIVDLSQEEDDKEEDEEEDEDNKNNISDLLEKTAEDIEEERAIKEMCYKSGEYYRIQYPQEHQSTEMVSPSPSLENEQLPMETIEHDLWKGDSNTIPTKFNNMERERETSGRKVSVQCMSRTHDKSCENEGGDYFAAQRNKYVNGKRSEALPFEKPPTASKYSNIKATNSSERVRKYHFKGVKKKKWISEEQRNSPNTGTDKGIPTSHSKVRTNYQQNYQRKDDETASSIRSVRQTERNTYFNSAEPRRSTYVFYRNTRVIQEPTFNGYTDKYSSGSYNAPTWRKRNPHAKTFSKFKTTIQSQAGMEMKKKGE", "length": 405, "header": "tr|A0A8V0YAN0-1|A0A8V0YAN0_CHICK Isoform 1 of Chromosome 12 open reading frame 50 OS=Gallus gallus OX=9031 GN=C12orf50 PE=4 SV=1 CANONICAL=A0A8V0YAN0-1" }, "locus": { "chromosome": "1", "start_pos": 42848150, "end_pos": 42835766, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027212.1", "url": 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"url": "https://omabrowser.org/oma/group/A0A8V0YAN0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3YX67-1", "protein_name": "RIKEN cDNA 1700017N19 gene", "gene_name": "1700017N19Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMQQNCSISCFWETQPLGCVKISCIFYHSKPRNINGLFLPPSSNTTLQKESQEGSPSPTQSQESLKPMENVSRPIHHPLVLKTNFEEEEEEEEEPNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRFHAPPDIPSSKSVAPTVEKELEKPLETGSELQEGDGLTVPTKFSLFERAGEAKTSLDRKPRTDIAAFENGGGDCYAPQRIIFLGVDESEALAEDKEATSKCSNVKEESKNGLHPKHPLTTRLMPTTHVLNATENISMKCRETPSSMNDVQPVRKPHFKGVKKRKWIYDEPKNFPGSGMRRAVHIPNPKHKMSYHHHNKNRNAENASYTHAPRDAVRTVTLNAPPRSRPTSRSYNKADVNKEPKLNLCPDKHMSTSYNGSAWRRRIPFSKTYSKTEKVYPEPRRNGSK", "length": 415 }, "evidence": [ { "id": "A0A8V0YAN0", "url": "https://omabrowser.org/oma/group/A0A8V0YAN0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1SPZ2-1", "protein_name": "Chromosome 5 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"MEMQQNCSISCFWETQPLGCVKISCIFYHSKPRNINGLFLPPSSNTTLQKESQEGSPPPTQSQEPLKPMENVSRPIHHPLVLKTNFEEEEEEEEKPNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRFHAPPDIPSSKSIAPTVEKELEKPLENGSELQEGDGLTVPTKFSLFERAGEAKTSLDRKPRTDIAAFENGGGDCYAPQRIIFLGVDESEALAEDKETTSKGSNAKEESKNGLHPKHPLTARLVPTTHVLNATENISMKCRENPSSMNDVQPVRKPHFKGVKKRKWIYDEPKNFPGSGMRRAVHIPNPKHKMSYHHHNKNRNAENASYTHAQRDAVRTVTLNAPPRSRPTSGSYNKADVNKDPKLNLCPDKHMSTSYNGSAWRRRIPFSKTYSKTEKIYPEPRRNGSK", "length": 415 }, "evidence": [ { "id": "A0A8V0YAN0", "url": "https://omabrowser.org/oma/group/A0A8V0YAN0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NA57-1", "protein_name": "Uncharacterized protein C12orf50", "gene_name": "C12orf50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMQQNCSISCFWETQPLGCVKISCIFYHSKPRNINGLFLPPSSNITLQKEIQEGIPLQSQSQEPLKPQENISRPIHHPLVLKTNFEEEEEVDEQNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRFHTPPDILSSKSMTPTAEKQLEKPLENGSELQEGDSLTVPTKLSQYERQGEIKTSLHGKPKTDIAAFENGGGDCYVPQRVIFLGVDESEALTEEKEITISKCSNTKDNKDSPHPKHSLTTRLVPTTHVLNATENISMKCREDPSSMNDVQPVKKPHFKGVKKRKWIYDEPQNFPNSGMQRAVQAPRPQNKMSYHRNNKNRNAENASYIHVQRDAVRTVALNAPSRSRPTHGSYNKVHANREPKPNLSPDKYTSTSYNDSAWRKRIPFSKTYSKSEKIYPEPRRNGSK", "length": 414 }, "evidence": [ { "id": "A0A8V0YAN0", "url": "https://omabrowser.org/oma/group/A0A8V0YAN0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416097.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416097" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFC3H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ2", "locus": { "chromosome": "1", "start_pos": 36462800, "end_pos": 36500607, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011696", "url": "https://www.ensembl.org/id/ENSGALG00010011696" } ] } } ], "crossref": [ { "id": "417855", "url": "https://www.ncbi.nlm.nih.gov/gene/417855", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"MAAAEAAPAEAALDSSGLSPKEEGELEDGEISDDDNNGSGPCGGGSEPGGGLAGNRPYSRRRPPPGLRGGISLSSSRRFPRSRHQPPPEMGHLHGHGGYRPKDSFRSHPPPLPAPRMPSGPHSETGPRLSFWERSHNALDRFRFRGRPYRGGWRWGRSRGGGERGGNPPGRPPGGGSCAGFSGNQGWREPSPRKSKTFGRSPSRKQNYSSKSENSVEESFEDLLLKYKQIQLELEYINKDERLALSNREENKQQDDSKTADTEDQITVENDSIKTDAIKEVSPEEKNPVMAFQAFELKPLRQKLPTPAERSRLKKVKEGTKQSSQKSEATESTQGAEDKEQTSTRKPSSSDVTSEKKLLEEEEEMSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVTQKVKASAKAHSTKKTSSTGKQTLRKQQTKTSKKIQQQKEQDRRQKEEDQRKQEEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSRSSDTDLRWSLDKPSTDSAGGIYQYDNYDEVAMDTDSETNSPASSPAQPPYFECPVGYYPPPTIPPISLPLPPPIPPLPSLSQLYMEGISCVSLEPPPPLPPLPPEEPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFRSEETSSNSGPPSPPVPDNLQSVPRSNLSAVSINTVSQPRVQNTKFVRVPRPPRAVITLPKHKSVVVTLNDSDDSESDGEPSNSTNSVFGGLESMIKEARRNVEASRIKAPPKSEKENDPMRTPEALPEDKKIEYRLLKEEIASREKQRLVKSDPLKNSSSPANSDGEVDGIGRIAVATKQVTEAEAKLKRNKLLLMKDESVLKHLLQQEAKKRENVRIAENKINKLAEQLQATEKILNANKMFLKKLQEQIHKVQQRVTVKKALALKYGEELARAKAVASKEIGKRKLEQEHLGPSKMLKLENSPASSPKKHSAELIALEKKRLQQLEYEYALKIQKLKEARALQTKEQSDIAPQAEEEAEFALPQPSLHDLTQDKLSLDSEENYFDDEVLSNSNRERRRSFRESSSYTKPNLKHMDTPKQEPINKLSKKAAEEPELFLGLNIDELKKLYAKADSLKELLVKSTAFVAPKEDLLCGQEISVDMDFVTSQNKQTEAKPFPFGPYRSPLLVFKSYRFSPYFRTKEKLYLSSVTYSNMIEPKQCFCRFDLTGTCNDDDCQWQHMKDCTLSRKQLFQDILSYNLELIGCSEKSTDEEISTATEKYVEKLFGINRDRMSVDQMAVLLASNVNESKGHTPPFTTWKDKRKWRPKYWRKPLLDSSSSEEEQSGPIKYAHPTEHKKRIPALDTVVTPDDIRYFTSETDDISNLEASVQENPCNVQLWIKLAYKYLNQNEGSSSECLDSTLNVLARALENNKENPEIWCHYLRLFSKRGTKEEIQEMCETAVEYAASYQIWWTFLNLESSFDGKDYVCGRILQFLMEVTEGEENPNLLSFQLLETLLYRVHLSLFTGRYQNALLLLQNALKSANEKIISERLTLSDRCLAWLSYIHLIEFNILPVKFYDPANVGPSRIMNKEPFLIPWQTVQDVKTDPDTLLAMFEDAVKTCTDENLEADKRIAVCFPLYRNMIALLKLLERWESAVELCRSLLELCPNNCLLLESLATLYLQMEQSESAYGVWIGAFEKNTQNAEIFYQLCKFLTSQERSDSVLPLLQDFVAAFFENTYQQHDSMDLLRYLLNFPMPIEFTAPLYKEHLTDDIVNQQIPYLWQIYCLCQSLHASVGEALDAYEAALGAVMQQEIVQNIWMDYLVFMNNKVVGSSNKVQEFKVFTDLVNRCLVTVPTRYPIPFSAADYWTNYEFHNKVVFFYLSCIPKSQHSKTLERFCSTMPANPGLALRLLLRYWEESNVQILKLQAKMFTYNIPTCLAIWKIAIAAECFLMGQREVHHLYQRALHKLPLCATLWKDQLLFEASGGGKTDNLRKLVSKCQEVGVSLDELLSLNTCRTECKNL", "length": 1984, "header": "tr|A0A8V0YAQ2-1|A0A8V0YAQ2_CHICK Isoform 1 of Zinc finger C3H1-type containing OS=Gallus gallus OX=9031 GN=ZFC3H1 PE=4 SV=1 CANONICAL=A0A8V0YAQ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ2/entry#A0A8V0YAQ2-1", "sequence": { "sequence": "MAAAEAAPAEAALDSSGLSPKEEGELEDGEISDDDNNGSGPCGGGSEPGGGLAGNRPYSRRRPPPGLRGGISLSSSRRFPRSRHQPPPEMGHLHGHGGYRPKDSFRSHPPPLPAPRMPSGPHSETGPRLSFWERSHNALDRFRFRGRPYRGGWRWGRSRGGGERGGNPPGRPPGGGSCAGFSGNQGWREPSPRKSKTFGRSPSRKQNYSSKSENSVEESFEDLLLKYKQIQLELEYINKDERLALSNREENKQQDDSKTADTEDQITVENDSIKTDAIKEVSPEEKNPVMAFQAFELKPLRQKLPTPAERSRLKKVKEGTKQSSQKSEATESTQGAEDKEQTSTRKPSSSDVTSEKKLLEEEEEMSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVTQKVKASAKAHSTKKTSSTGKQTLRKQQTKTSKKIQQQKEQDRRQKEEDQRKQEEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSRSSDTDLRWSLDKPSTDSAGGIYQYDNYDEVAMDTDSETNSPASSPAQPPYFECPVGYYPPPTIPPISLPLPPPIPPLPSLSQLYMEGISCVSLEPPPPLPPLPPEEPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFRSEETSSNSGPPSPPVPDNLQSVPRSNLSAVSINTVSQPRVQNTKFVRVPRPPRAVITLPKHKSVVVTLNDSDDSESDGEPSNSTNSVFGGLESMIKEARRNVEASRIKAPPKSEKENDPMRTPEALPEDKKIEYRLLKEEIASREKQRLVKSDPLKNSSSPANSDGEVDGIGRIAVATKQVTEAEAKLKRNKLLLMKDESVLKHLLQQEAKKRENVRIAENKINKLAEQLQATEKILNANKMFLKKLQEQIHKVQQRVTVKKALALKYGEELARAKAVASKEIGKRKLEQEHLGPSKMLKLENSPASSPKKHSAELIALEKKRLQQLEYEYALKIQKLKEARALQTKEQSDIAPQAEEEAEFALPQPSLHDLTQDKLSLDSEENYFDDEVLSNSNRERRRSFRESSSYTKPNLKHMDTPKQEPINKLSKKAAEEPELFLGLNIDELKKLYAKADSLKELLVKSTAFVAPKEDLLCGQEISVDMDFVTSQNKQTEAKPFPFGPYRSPLLVFKSYRFSPYFRTKEKLYLSSVTYSNMIEPKQCFCRFDLTGTCNDDDCQWQHMKDCTLSRKQLFQDILSYNLELIGCSEKSTDEEISTATEKYVEKLFGINRDRMSVDQMAVLLASNVNESKGHTPPFTTWKDKRKWRPKYWRKPLLDSSSSEEEQSGPIKYAHPTEHKKRIPALDTVVTPDDIRYFTSETDDISNLEASVQENPCNVQLWIKLAYKYLNQNEGSSSECLDSTLNVLARALENNKENPEIWCHYLRLFSKRGTKEEIQEMCETAVEYAASYQIWWTFLNLESSFDGKDYVCGRILQFLMEVTEGEENPNLLSFQLLETLLYRVHLSLFTGRYQNALLLLQNALKSANEKIISERLTLSDRCLAWLSYIHLIEFNILPVKFYDPANVGPSRIMNKEPFLIPWQTVQDVKTDPDTLLAMFEDAVKTCTDENLEADKRIAVCFPLYRNMIALLKLLERWESAVELCRSLLELCPNNCLLLESLATLYLQMEQSESAYGVWIGAFEKNTQNAEIFYQLCKFLTSQERSDSVLPLLQDFVAAFFENTYQQHDSMDLLRYLLNFPMPIEFTAPLYKEHLTDDIVNQQIPYLWQIYCLCQSLHASVGEALDAYEAALGAVMQQEIVQNIWMDYLVFMNNKVVGSSNKVQEFKVFTDLVNRCLVTVPTRYPIPFSAADYWTNYEFHNKVVFFYLSCIPKSQHSKTLERFCSTMPANPGLALRLLLRYWEESNVQILKLQAKMFTYNIPTCLAIWKIAIAAECFLMGQREVHHLYQRALHKLPLCATLWKDQLLFEASGGGKTDNLRKLVSKCQEVGVSLDELLSLNTCRTECKNL", "length": 1984, "header": "tr|A0A8V0YAQ2-1|A0A8V0YAQ2_CHICK Isoform 1 of Zinc finger C3H1-type containing OS=Gallus gallus OX=9031 GN=ZFC3H1 PE=4 SV=1 CANONICAL=A0A8V0YAQ2-1" }, "locus": { "chromosome": "1", "start_pos": 36500408, "end_pos": 36463500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027994.1", "url": "https://www.ensembl.org/id/ENSGALT00010027994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016057.1", "url": "https://www.ensembl.org/id/ENSGALP00010016057.1" } ] } }, { "isoform_ac": "A0A8V0YC66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ2/entry#A0A8V0YC66-1", "sequence": { "sequence": "MTTTAPGRAAAAPSPAVAWRATGPTRGAGRLPVSAAASPSRPLGVSRGRGTSPRPRWATYTVTARGGNPPGRPPGGGSCAGFSGNQGWREPSPRKSKTFGRSPSRKQNYSSKSENSVEESFEDLLLKYKQIQLELEYINKDERLALSNREENKQQDDSKTADTEDQITVENDSIKTDAIKEVSPEEKNPVMAFQAFELKPLRQKLPTPAERSRLKKVKEGTKQSSQKSEATESTQGAEDKEQTSTRKPSSSDVTSEKKLLEEEEEMSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVTQKVKASAKAHSTKKTSSTGKQTLRKQQTKTSKKIQQQKEQDRRQKEEDQRKQEEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSRSSDTDLRWSLDKPSTDSAGGIYQYDNYDEVAMDTDSETNSPASSPAQPPYFECPVGYYPPPTIPPISLPLPPPIPPLPSLSQLYMEGISCVSLEPPPPLPPLPPEEPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFRSEETSSNSGPPSPPVPDNLQSVPRSNLSAVSINTVSQPRVQNTKFVRVPRPPRAVITLPKHKSVVVTLNDSDDSESDGEPSNSTNSVFGGLESMIKEARRNVEASRIKAPPKSEKENDPMRTPEALPEDKKIEYRLLKEEIASREKQRLVKSDPLKNSSSPANSDGEVDGIGRIAVATKQVTEAEAKLKRNKLLLMKDESVLKHLLQQEAKKRENVRIAENKINKLAEQLQATEKILNANKMFLKKLQEQIHKVQQRVTVKKALALKYGEELARAKAVASKEIGKRKLEQEHLGPSKMLKLENSPASSPKKHSAELIALEKKRLQQLEYEYALKIQKLKEARALQTKEQSDIAPQAEEEAEFALPQPSLHDLTQDKLSLDSEENYFDDEVLSNSNRERRRSFRESSSYTKPNLKHMDTPKQEPINKLSKKAAEEPELFLGLNIDELKKLYAKADSLKELLVKSTAFVAPKEDLLCGQEISVDMDFVTSQNKQTEAKPFPFGPYRSPLLVFKSYRFSPYFRTKEKLYLSSVTYSNMIEPKQCFCRFDLTGTCNDDDCQWQHMKDCTLSRKQLFQDILSYNLELIGCSEKSTDEEISTATEKYVEKLFGINRDRMSVDQMAVLLASNVNESKGHTPPFTTWKDKRKWRPKYWRKPLLDSSSSEEEQSGPIKYAHPTEHKKRIPALDTVVTPDDIRYFTSETDDISNLEASVQENPCNVQLWIKLAYKYLNQNEGSSSECLDSTLNVLARALENNKENPEIWCHYLRLFSKRGTKEEIQEMCETAVEYAASYQIWWTFLNLESSFDGKDYVCGRILQFLMEVTEGEENPNLLSFQLLETLLYRVHLSLFTGRYQNALLLLQNALKSANEKIISERLTLSDRCLAWLSYIHLIEFNILPVKFYDPANVGPSRIMNKEPFLIPWQTVQDVKTDPDTLLAMFEDAVKTCTDENLEADKRIAVCFPLYRNMIALLKLLERWESAVELCRSLLELCPNNCLLLESLATLYLQMEQSESAYGVWIGAFEKNTQNAEIFYQLCKFLTSQERSDSVLPLLQDFVAAFFENTYQQHDSMDLLRYLLNFPMPIEFTAPLYKEHLTDDIVNQQIPYLWQIYCLCQSLHASVGEALDAYEAALGAVMQQEIVQNIWMDYLVFMNNKVVGSSNKVQEFKVFTDLVNRCLVTVPTRYPIPFSAADYWTNYEFHNKVVFFYLSCIPKSQHSKTLERFCSTMPANPGLALRLLLRYWEESNVQILKLQAKMFTYNIPTCLAIWKIAIAAECFLMGQREVHHLYQRALHKLPLCATLWKDQLLFEASGGGKTDNLRKLVSKCQEVGVSLDELLSLNTCRTECKNL", "length": 1885, "header": "tr|A0A8V0YC66-1|A0A8V0YC66_CHICK Computationally mapped isoform of Zinc finger C3H1-type containing OS=Gallus gallus OX=9031 GN=ZFC3H1 PE=4 SV=1 CANONICAL=A0A8V0YAQ2-1" }, "locus": { "chromosome": "1", "start_pos": 36500308, "end_pos": 36463500, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027988.1", "url": "https://www.ensembl.org/id/ENSGALT00010027988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016055.1", "url": "https://www.ensembl.org/id/ENSGALP00010016055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A504-1", "protein_name": "Zinc finger, C3H1-type containing", "gene_name": "Zfc3h1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATADTSTPASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSTSSSGGGLLPYPRRRPPHPTRGGGSGGGGGSSSSSSSSQQQLRNFSRSRHPSERGHLRGHSSYRPKEPFRTHPPPVRMSSGSLSESSPRPSFWERSHIALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPLGGGGGGGGAGSGFGSSQSWREPSPPRKSSKSFGRSPSRKQNHSSKSENCGEETFEDLLLKYKQIQLELECINKDEKLALSSKEETVQEDPKTLHLEDQAGTNNANVTKDPSKEGAPEEKTQLKTFQAFELKPLRQKLTLPGDKNRVKRGKDGAKQLPLKSSTTDASQGLEDKEQNITRRISASDILSEKKLGEEEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTTQQKAKASTKAHSTKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKHAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLEKQPESGGGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFPECSLGYFSSAPSVSLPPPAQVSSVPSLSQPFGEGLCASLDPLPPLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKPEEASSNSDPPSPPVLNNSQPLSRSNLSIVSINTVSQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTSSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEMDGIGRIAMVTKQVADAEAKLKKHKILLIKDESVLKNLVLQEAKKKESVRNAEAKITKLTEQLQAAEKILSVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKELGKRKLEQDRLGPNKMMRLDNSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNLVPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDADDEVLSGSNRERRRSFLESNSFTKPNLKHTDTPNKECVNKLSKSTVEKPELFLGLKIGELQKLYSKADSLKQLILKTTTGITENILHGQEISVDVDFVTAQSKTTEVKPCPFRPYQSPLLVFKSYRFSPYYRTKEKLPLSSVSYSNMIEPDQCFCRFDLAGTCNDDDCQWQHVQDYTLSRKQLFQDILSYNLSLIGCSETSTDEEIASATEKYVEKLFGVNKDRMSMDQMAVLLVSNVNESKGHTPPFTTYKDKRKWKPKFCRKPASENSCSSDDEQSTGPIKYAFRPENQINVPALDTVVTPDDVRYFTSETDDIANLEASVLENPSHVQLWLKLAYKYLNQNEGLCSESLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVEYAPDYQSFCTFLHLESTFEEKDYVCERMVEFLMGAAKRETSDILSFQLLEALLFRVQLHIFTGRCQSALAILQNALKLANDAIVAEYLRTEDRCLAWLAYIHLIEFNSLPSKLYDPSNANPSRIVNTEPFVMPWQAAQDVKTNPDLLLAVFEDAVKACTDEALTSGERTEVCLPLYTNMMALHQLLERDEEAVELCKSLLESCPTNCQLLETLAALYLKTDCYDKARWVWLTAFENNPQNAEIFYHLCKFFILQNGGDKLLPLLRQFIGSFFKPGFEKYSNVDLFRYLLNIPGPLDIPACLCKGNFDDDVFNNQVPYLWLIYCLCHPLQSSIKETIEAYEAALGVAMRSDIVQKIWMDYLVFANNRAAGSRNKVQEFKFFTDLVNRCLVTVPARYPIPFSSADYWSNYEFHNRVIFFYLSCVPKTQHSKTLERFCSVMPANSRLALRLLQHEWEESNVQILKLQAKMFTYNLPTCLATWKIAIAAEIALKGQREVHRLYQRALQKLPLCASLWKDQLLFEASEGGKTDNLRKLVSKCQEIGVSLNELLNLNSNKTESKNL", "length": 1994 }, "evidence": [ { "id": "A0A8V0YAQ2", "url": "https://omabrowser.org/oma/group/A0A8V0YAQ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BIV7-1", "protein_name": "Zinc finger C3H1-type containing", "gene_name": "ZFC3H1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATADTPALASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPLHPARGGGSGGGGGSSSSSSSSQLQLRNFSRSRHASERGHLRGHSSYRPKEPFRSHPPSVRMPSSSLSESSPRPSFWERSHIALDRFRFRGRPYRGGSRWSRGRGGGDRGGKPGGRPLGGGAGSGFGSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKSENCGEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSIIKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGTKQLSLKSDATESSPGLEDKEQNLTRRISASDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQATDSGGGIYQYDNYEEVAMDTDSETNSPAPSPVQPPFFSECSLGYFSPAPSISLPPPPQVSSVPPLSQPYVEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLNNSQPMPRSNLSIVSINTVSQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPMRTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIALVTKQVTDAEAKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAETKITKLTEQLQATEKILSVNRMFLKKLQEQIHRVQQRITIKKALTLKYGEELARAKAVASKEIGKRKLEQDRLGPNKMMRLDNSPISSPRRHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNIAPLVEEEPEFSLPQPSLHDLTQDKLSLDTEENDVDDEILSGSNRERRRSFLESNSFTKPNLKHTDTPNKECINKPTKNTVEKPELFLGLKIGELQKLYSKADSLKQLILKTTTGISDKVLHGQEISVDVDFVTAQSKTTEVKPCPFRPYHSPLLVFKSYRFSPYYRTKEKLPLSSVSYSNMIEPDQCFCRFDLTGTCNDDDCQWQHTQDYTLSRKQLFQDVLSYNLSLIGCSEGSTDEEIAAAAEKYVEKLFGVNKDRMSMDQMAVLLVSNINESKGHTPPFTTYKDKRKWKPKFWRKPISENNFSSDEEQSTGPIKYAFQPENRINVPALDTVVTPDDVRYFTNETDDIANLEASVLENPSHVQLWLKLAYKYLNQNEGLCSESLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKEEVQEMCETAVEYAPDYQSFWTFLHLESTFEEKDYVCERMVEFLMGAAKREASDTLSFQLLEALLFRVQLHIFTGRCQSALAILQNALKLATDGRVAEYLKTSDRCLAWLAYIHLIEFNILPSKFYDPSNANPSRIVNIEPFVMPWQAVQDVKTNPDMLFAVFEDAVKACTDESLTVEERVETCVPLYTNMIVLHQLLERYEAAVELCKCLLESCPMNCQLLESLAALYLKMNQQDKARAVWVTAFEKSPQNAEVFYHTCKFFILQNRGDNLLPFLRKFIASFFKPGFEKYSNLDLFRYLLNIPGPLDIPACLCKGNFDDEMFNHQVPYLWLIYCLCHPLQSSIKETVEAYEAALGVAMRSDIVQKIWMDYLVFANNRAAGSRNKVQEFKFFTDLVNRCLVTVPARYPIPFSSADYWSNYEFHNRVIFFYLSCVPKTQHSKTLERFCSIMPTNSGLALRLLQHEWEESNVQILKLQAKMFTYNIPTCLATWKIAIAAEIVLKGQREVHRLYQRALQKLPLCASLWKDQLLFEASEGGKTDNLRKLVSKCQEIGVSLNELLNLNSYKTESKNH", "length": 1988 }, "evidence": [ { "id": "A0A8V0YAQ2", "url": "https://omabrowser.org/oma/group/A0A8V0YAQ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O60293-1", "protein_name": "Zinc finger C3H1 domain-containing protein", "gene_name": "ZFC3H1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATADTPAPASSGLSPKEEGELEDGEISDDDNNSQIRSRSSSSSSGGGLLPYPRRRPPHSARGGGSGGGGGSSSSSSSSQQQLRNFSRSRHASERGHLRGPSSYRPKEPFRSHPPSVRMPSSSLSESSPRPSFWERSHLALDRFRFRGRPYRGGSRWSRGRGVGERGGKPGCRPPLGGGAGSGFSSSQSWREPSPPRKSSKSFGRSPSRKQNYSSKNENCVEETFEDLLLKYKQIQLELECINKDEKLALSSKEENVQEDPKTLNFEDQTSTDNVSITKDSSKEVAPEEKTQVKTFQAFELKPLRQKLTLPGDKNRLKKVKDGAKPLSLKSDTTDSSQGLQDKEQNLTRRISTSDILSEKKLGEDEEELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTAKQALRKQQTKAWKKLQQQKEQERQKEEDQRKQAEEEERRKREEEIRKIRDLSNQEEQYNRFMKLVGGKRRSRSKSSDPDLRRSLDKQPTDSGGGIYQYDNYEEVAMDTDSETSSPAPSPVQPPFFSECSLGYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVSLEPLPPLPPLPPLPPEDPEQPPKPPFADEEEEEEMLLREELLKSLANKRAFKPEETSSNSDPPSPPVLNNSHPVPRSNLSIVSINTVSQPRIQNPKFHRGPRLPRTVISLPKHKSVVVTLNDSDDSESDGEASKSTNSVFGGLESMIKEARRTAEQASKPKVPPKSEKENDPLRTPEALPEEKKIEYRLLKEEIANREKQRLIKSDQLKTSSSSPANSDVEIDGIGRIAMVTKQVTDAESKLKKHRILLMKDESVLKNLVQQEAKKKESVRNAEAKITKLTEQLQATEKILNVNRMFLKKLQEQIHRVQQRVTIKKALTLKYGEELARAKAVASKEIGKRKLEQDRFGPNKMMRLDSSPVSSPRKHSAELIAMEKRRLQKLEYEYALKIQKLKEARALKAKEQQNISPVVEEEPEFSLPQPSLHDLTQDKLTLDTEENDVDDEILSGSSRERRRSFLESNYFTKPNLKHTDTANKECINKLNKNTVEKPELFLGLKIGELQKLYSKADSLKQLILKTTTGITEKVLHGQEISVDVDFVTAQSKTMEVKPCPFRPYHSPLLVFKSYRFSPYYRTKEKLPLSSVSYSNMIEPDQCFCRFDLTGTCNDDDCQWQHIQDYTLSRKQLFQDILSYNLSLIGCAETSTNEEITASAEKYVEKLFGVNKDRMSMDQMAVLLVSNINESKGHTPPFTTYKDKRKWKPKFWRKPISDNSFSSDEEQSTGPIKYAFQPENQINVPALDTVVTPDDVRYFTNETDDIANLEASVLENPSHVQLWLKLAYKYLNQNEGECSESLDSALNVLARALENNKDNPEIWCHYLRLFSKRGTKDEVQEMCETAVEYAPDYQSFWTFLHLESTFEEKDYVCERMLEFLMGAAKQETSNILSFQLLEALLFRVQLHIFTGRCQSALAILQNALKSANDGIVAEYLKTSDRCLAWLAYIHLIEFNILPSKFYDPSNDNPSRIVNTESFVMPWQAVQDVKTNPDMLLAVFEDAVKACTDESLAVEERIEACLPLYTNMIALHQLLERYEAAMELCKSLLESCPINCQLLEALVALYLQTNQHDKARAVWLTAFEKNPQNAEVFYHMCKFFILQNRGDNLLPFLRKFIASFFKPGFEKYNNLDLFRYLLNIPGPIDIPSRLCKGNFDDDMFNHQVPYLWLIYCLCHPLQSSIKETVEAYEAALGVAMRCDIVQKIWMDYLVFANNRAAGSRNKVQEFKFFTDLVNRCLVTVPARYPIPFSSADYWSNYEFHNRVIFFYLSCVPKTQHSKTLERFCSVMPANSGLALRLLQHEWEESNVQILKLQAKMFTYNIPTCLATWKIAIAAEIVLKGQREVHRLYQRALQKLPLCASLWKDQLLFEASEGGKTDNLRKLVSKCQEIGVSLNELLNLNSNKTESKNH", 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"locus": {} } ], "crossref": [ { "id": "A0A8V0YAQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YAQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FKSLAFPCECSVTVITIVYMCLHVCALINSLLEFQIFPFKSSWYTCELIFPVYSSVSDRQLPKCLTKCFY", "length": 70, "header": "tr|A0A8V0YAQ3-1|A0A8V0YAQ3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YAQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ3/entry#A0A8V0YAQ3-1", "sequence": { "sequence": "FKSLAFPCECSVTVITIVYMCLHVCALINSLLEFQIFPFKSSWYTCELIFPVYSSVSDRQLPKCLTKCFY", "length": 70, "header": "tr|A0A8V0YAQ3-1|A0A8V0YAQ3_CHICK Isoform 1 of Uncharacterized 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAQ5-1", "uniprot_ac": "A0A8V0YAQ5", "uniprot_id": "A0A8V0YAQ5_CHICK", "mass": { "chemical_mass": 15796.0, "monoisotopic_mass": 15796.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YAQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", 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"MGREVTFGCGVTLVGREVVSVGREVALVGRRVALMGWEVALMGLEMTLGCGVALVGREVALVGHRGALVGQEVTLVEHRGALVGWEVALMGLEVTLGCGVAVVGQEVAVVGLEVVPVGWEVTLVGQRVALMGWEVTLVGRRVALMGQEVVAV", "length": 152, "header": "tr|A0A8V0YAQ5-1|A0A8V0YAQ5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YAQ5-1" }, "locus": { "chromosome": "38", "start_pos": 350767, "end_pos": 350312, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026058.1", "url": "https://www.ensembl.org/id/ENSGALT00010026058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014698.1", "url": "https://www.ensembl.org/id/ENSGALP00010014698.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAR1-1", "uniprot_ac": "A0A8V0YAR1", "uniprot_id": "A0A8V0YAR1_CHICK", "mass": { "chemical_mass": 33750.0, "monoisotopic_mass": 33750.0 }, "refseq": { "ac": "NP_001186462", "name": "nuclear receptor-binding factor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186462" }, "gene_names": [ { "name": "NRBF2", "type": "recommended", "evidence": [ { "id": "A0A8V0YAR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ] }, { "name": "NRBF2", "type": "synonym", "evidence": [ { "id": "NP_001186462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186462" } ] }, { "name": "RBF-2", "type": "synonym", "evidence": [ { "id": "NP_001186462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186462" } ] } ], "protein_names": [ { "name": "Nuclear receptor-binding factor 2", "type": "recommended", "evidence": [ { "id": "A0A8V0YAR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor-binding factor 2", "type": "synonym", "evidence": [ { "id": "NP_001186462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186462" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX950839.2, HAEL01011473.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992437, SAMEA103992453 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1. On Dec 9, 2010 this sequence version replaced XP_421538.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186462" } ] }, { "annotation": "Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilizes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3. Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1#function" }, { "database": "UniProtKB", "id": "ARBA00054797", "url": "https://www.uniprot.org/uniprotkb/ARBA00054797#function" } ] }, { "annotation": "May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1#function" }, { "database": "UniProtKB", "id": "ARBA00059930", "url": "https://www.uniprot.org/uniprotkb/ARBA00059930#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NRBF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1", "locus": { "chromosome": "6", "start_pos": 8655655, "end_pos": 8669817, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009462", "url": "https://www.ensembl.org/id/ENSGALG00010009462" } ] } } ], "crossref": [ { "id": "A0A8V0YAR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "423656", "url": "https://www.ncbi.nlm.nih.gov/gene/423656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423656", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCHETVA", "url": "https://omabrowser.org/oma/group/KCHETVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAQ6", "url": "https://www.orthodb.org/?gene=A0A8V0YAQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAR1", "url": "https://www.orthodb.org/?gene=A0A8V0YAR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14964:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14964:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08961", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08961", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPQPPPSMEVMEGPLNLAHQQSRKADRLLAAGKYEEAISCHRKAAAYLTEAMKLTQSEQAQLSLELQRDSHMKQLLLIQERWKRAKREEKMKAQQNADKELAAHLQTSFKPSAEESDDQNVLIPVTQKYSPSTEKHLQDIQGVFDRDPDTLLFLLQKKNEPVETCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAERARLQKSPVEKELDVDADFVEKSELWGLQQHSETASSAASWQDFATTAGKAKDIPIPNLPPLDIPSPELPLLELSEDMLKGLMNS", "length": 298, "header": "tr|A0A8V0YAR1-1|A0A8V0YAR1_CHICK Isoform 1 of Nuclear receptor-binding factor 2 OS=Gallus gallus OX=9031 GN=NRBF2 PE=1 SV=1 CANONICAL=A0A8V0YAR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1/entry#A0A8V0YAQ6-1", "sequence": { "sequence": "MQTSSGFLHFIYQGKTQSYLTEAMKLTQSEQAQLSLELQRDSHMKQLLLIQERWKRAKREEKMKAQQNADKELAAHLQTSFKPSAEESDDQNVLIPVTQKYSPSTEKHLQDIQGVFDRDPDTLLFLLQKKNEPVETCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAERARLQKSPVEKELDVDADFVEKSELWGLQQHSETASSAASWQDFATTAGKAKDIPIPNLPPLDIPSPELPLLELSEDMLKGLMNS", "length": 269, "header": "tr|A0A8V0YAQ6-1|A0A8V0YAR1_CHICK Computationally mapped isoform of Nuclear receptor-binding factor 2 OS=Gallus gallus OX=9031 GN=NRBF2 PE=1 SV=1 CANONICAL=A0A8V0YAR1-1" }, "locus": { "chromosome": "6", "start_pos": 8658676, "end_pos": 8656489, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022598.1", "url": "https://www.ensembl.org/id/ENSGALT00010022598.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013029.1", "url": "https://www.ensembl.org/id/ENSGALP00010013029.1" } ] } }, { "isoform_ac": "A0A8V0YAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1/entry#A0A8V0YAR1-1", "sequence": { "sequence": "MCPQPPPSMEVMEGPLNLAHQQSRKADRLLAAGKYEEAISCHRKAAAYLTEAMKLTQSEQAQLSLELQRDSHMKQLLLIQERWKRAKREEKMKAQQNADKELAAHLQTSFKPSAEESDDQNVLIPVTQKYSPSTEKHLQDIQGVFDRDPDTLLFLLQKKNEPVETCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRRENKQLKAERARLQKSPVEKELDVDADFVEKSELWGLQQHSETASSAASWQDFATTAGKAKDIPIPNLPPLDIPSPELPLLELSEDMLKGLMNS", "length": 298, "header": "tr|A0A8V0YAR1-1|A0A8V0YAR1_CHICK Isoform 1 of Nuclear receptor-binding factor 2 OS=Gallus gallus OX=9031 GN=NRBF2 PE=1 SV=1 CANONICAL=A0A8V0YAR1-1" }, "locus": { "chromosome": "6", "start_pos": 8669739, "end_pos": 8656489, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022602.1", "url": "https://www.ensembl.org/id/ENSGALT00010022602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013034.1", "url": "https://www.ensembl.org/id/ENSGALP00010013034.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423656", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423656", "resource": "KEGG Pathway" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8VCQ3-1", "protein_name": "Nuclear receptor-binding factor 2", "gene_name": "Nrbf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHRKATTYLSEAMKLTESEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQSTERDGAPHLQAPPRPSEDAEGQSPLLSQPYIPSTERRLPEVQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGTAEKELDVDADFVEKSELWGLPSHSESAAASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND", "length": 287 }, "evidence": [ { "id": "A0A8V0YAR1", "url": "https://omabrowser.org/oma/group/A0A8V0YAR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96F24-1", "protein_name": "Nuclear receptor-binding factor 2", "gene_name": "NRBF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSPLSQKYSPSTEKCLPEIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN", "length": 287 }, "evidence": [ { "id": "A0A8V0YAR1", "url": "https://omabrowser.org/oma/group/A0A8V0YAR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYK3-1", "protein_name": "Nuclear receptor-binding factor 2", "gene_name": "Nrbf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKATAYLSEAMKLTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQSTDRDGVPHLQASHRPSEDSEGQSPLLSQTYIPSTEKRLPEEQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIAELKRHVEFLVAENERLRKENKQLKAEKARLLKGPAEKELDVDADFVEKSELWGLPPHSDTATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND", "length": 287 }, "evidence": [ { "id": "A0A8V0YAR1", "url": "https://omabrowser.org/oma/group/A0A8V0YAR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex, class III", "id": "GO:0035032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" }, { "id": "PF08961", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08961" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear receptor-binding factor 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 295, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YAR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAR1" }, { "id": "PF17169", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17169" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear receptor-binding factor 2 MIT", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 94, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAW5-1", "uniprot_ac": "A0A8V0YAW5", "uniprot_id": "A0A8V0YAW5_CHICK", "mass": { "chemical_mass": 141630.0, "monoisotopic_mass": 141630.0 }, "refseq": { "ac": "NP_001264679", "name": "ubinuclein-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264679" }, "gene_names": [ { "name": "UBN2", "type": "recommended", "evidence": [ { "id": "A0A8V0YAW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5" } ] }, { "name": "UBN2", "type": "synonym", "evidence": [ { "id": "NP_001264679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264679" } ] } ], "protein_names": [ { "name": "Ubinuclein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YAW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5/entry#names_and_taxonomy" } ] }, { "name": "ubinuclein-2", "type": "synonym", "evidence": [ { "id": "NP_001264679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264679" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.67538.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1, BX933829.1, CO635378.1, CR387652.1, AL587270.1, BU306772.1, BU311502.1 and AJ447680.1. On Nov 24, 2021 this sequence version replaced NP_001264679.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264679" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5", "locus": { "chromosome": "1", "start_pos": 49146978, "end_pos": 49099093, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010920", "url": "https://www.ensembl.org/id/ENSGALG00010010920" } ] } } ], "crossref": [ { "id": "417970", "url": "https://www.ncbi.nlm.nih.gov/gene/417970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417970", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417970", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKVKKVM", "url": "https://omabrowser.org/oma/group/PKVKKVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAW5", "url": "https://www.orthodb.org/?gene=A0A8V0YAW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21669", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21669", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21669:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21669:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264679", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264679", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPRRVPFISLSPVRRREAESPALERESGGREPEPPPAGREVPLLEPPPPPRESAARLEPPREPGRPEPPPQREPPRPEPPPPPRQGSRQEPPPPQEALPLRQTVRLEVVLKDPTEEGCVEFSYPELLLCREARKKSVHSEDPFNDEQRERHEVETLAKKFEAKYSGKPHKHRKDRLQDLIDIGYGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDDDFAEDKKHRPPKIAKLKESEDRGMKKRKRKDEGMEKEKKPRKMKVPKQLGVMALNSHKSEKKKKKFYKDSLSLAAMIRKFQKEKEAMRKKESSPKPPVTIATSTPSKVPSSSLSAGNDISDLNLKISDPVLSIFGSTNERDLLQETESALEMLGDIDFDKLLDGTSDGSPVSELSGENGNVTHATYTSQVMTPKQVPALPEGLPTLLEKRIGDLRTAAKMFDEEGRKKFFTQDMNNILLDIELQLQEINPAIRNGVYSHLEAFVPCNKDTLIKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLCKYQEDCQARNLAKNAKLQTEDEREKNGSEEDDDEKPGKRVVGPRKKFHWDDTVRSLLCNLVKIKLGCYELEPNRSQSAEDYLKTFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVILAPKPKVKDSSPKKEQKTCISSVNSSCGTTLSTGAPVCTPSSSSCTPAPETICLDDSLDEDLSFHPPSLDSISDALAVINNGAKGSPLGSAIETPTSRPRPGLREEKLASIMSKLPLATSKKVEPAQTPHSSSLIAGHTGPVPKKPQDLVHTGISSGLIAGSSIQNPKVSLEPLPAKLLQQGLQRSSQIQAAAASSQTHVSSSKTQAAISTTSQRPKDANILVSSSEVQGGSSTSQMTKVHQHSAVQQKYVSPLQATISKSQTNPVVKLSSNPKLSCSSPVIKAQEKSVVYRLPLSNPSSGSGSQVSHPLVSRTTSSTSTSSNYLAKAMVSQVSSQGFKPPFSMAASPKPAASPKPTASKPSVTPKPNASPKFSSKSTSSPRPAATPSSSSSSALVSQSSHSSNTPLHKQTSGVNISRQSPTMNLLPSNRTSGLQPAKNPQASSKLSNSSPSGTVGKNNLGGVGMNVPASRGSNLNSSGASRTSLSGGAGSGTQGATKQLSTPHRPSSASGSPVVAASVQSTAGASLLANASPLTLMASPLSVTSQNVTSAPLTPFGMLGGLVPVTVPFQFPLELLGFGTDTAGVTTTSGSTSAAFHHSLTQNLLKGLQPGAQHAAALSHSPLPAHLQQAYTDGGQSKGDTKLQRKNQ", "length": 1314, "header": "tr|A0A8V0YAW5-1|A0A8V0YAW5_CHICK Isoform 1 of Ubinuclein 2 OS=Gallus gallus OX=9031 GN=UBN2 PE=3 SV=1 CANONICAL=A0A8V0YAW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5/entry#A0A8V0YAW5-1", "sequence": { "sequence": "MAEPRRVPFISLSPVRRREAESPALERESGGREPEPPPAGREVPLLEPPPPPRESAARLEPPREPGRPEPPPQREPPRPEPPPPPRQGSRQEPPPPQEALPLRQTVRLEVVLKDPTEEGCVEFSYPELLLCREARKKSVHSEDPFNDEQRERHEVETLAKKFEAKYSGKPHKHRKDRLQDLIDIGYGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDSEDDDFAEDKKHRPPKIAKLKESEDRGMKKRKRKDEGMEKEKKPRKMKVPKQLGVMALNSHKSEKKKKKFYKDSLSLAAMIRKFQKEKEAMRKKESSPKPPVTIATSTPSKVPSSSLSAGNDISDLNLKISDPVLSIFGSTNERDLLQETESALEMLGDIDFDKLLDGTSDGSPVSELSGENGNVTHATYTSQVMTPKQVPALPEGLPTLLEKRIGDLRTAAKMFDEEGRKKFFTQDMNNILLDIELQLQEINPAIRNGVYSHLEAFVPCNKDTLIKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLCKYQEDCQARNLAKNAKLQTEDEREKNGSEEDDDEKPGKRVVGPRKKFHWDDTVRSLLCNLVKIKLGCYELEPNRSQSAEDYLKTFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVILAPKPKVKDSSPKKEQKTCISSVNSSCGTTLSTGAPVCTPSSSSCTPAPETICLDDSLDEDLSFHPPSLDSISDALAVINNGAKGSPLGSAIETPTSRPRPGLREEKLASIMSKLPLATSKKVEPAQTPHSSSLIAGHTGPVPKKPQDLVHTGISSGLIAGSSIQNPKVSLEPLPAKLLQQGLQRSSQIQAAAASSQTHVSSSKTQAAISTTSQRPKDANILVSSSEVQGGSSTSQMTKVHQHSAVQQKYVSPLQATISKSQTNPVVKLSSNPKLSCSSPVIKAQEKSVVYRLPLSNPSSGSGSQVSHPLVSRTTSSTSTSSNYLAKAMVSQVSSQGFKPPFSMAASPKPAASPKPTASKPSVTPKPNASPKFSSKSTSSPRPAATPSSSSSSALVSQSSHSSNTPLHKQTSGVNISRQSPTMNLLPSNRTSGLQPAKNPQASSKLSNSSPSGTVGKNNLGGVGMNVPASRGSNLNSSGASRTSLSGGAGSGTQGATKQLSTPHRPSSASGSPVVAASVQSTAGASLLANASPLTLMASPLSVTSQNVTSAPLTPFGMLGGLVPVTVPFQFPLELLGFGTDTAGVTTTSGSTSAAFHHSLTQNLLKGLQPGAQHAAALSHSPLPAHLQQAYTDGGQSKGDTKLQRKNQ", "length": 1314, "header": "tr|A0A8V0YAW5-1|A0A8V0YAW5_CHICK Isoform 1 of Ubinuclein 2 OS=Gallus gallus OX=9031 GN=UBN2 PE=3 SV=1 CANONICAL=A0A8V0YAW5-1" }, "locus": { "chromosome": "1", "start_pos": 49146522, "end_pos": 49099093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026146.1", "url": "https://www.ensembl.org/id/ENSGALT00010026146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014769.1", "url": "https://www.ensembl.org/id/ENSGALP00010014769.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1052, "start_aa": "Thr", "end_pos": 1052, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1052", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417970", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417970", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A666-1", "protein_name": "Ubinuclein-2", "gene_name": "Ubn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPRRVAFISLSPVRRREADFAGAEREPPRLEPQPYREPARAEPAPRADAQPPARDKPLPQREVSRAEPPMALQREPPRPEPPPPPLPLQTPPPRESASRAEPPPRPPKETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKLVHTEDPFTDEHKERQEVEMLAKKFEMKYGGKARKHRKDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDFTDNQKHKPPKVPKIKDDDIEAKKRKRKEEGEKEKKPRKKVPKQLGVVALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESTPKVPVIPSTSSLPKPPCAATTLGDDIPDLSLNSADPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDATSDGSPLSESGGENGNTTQPTFASQVVPKVVPTLPDGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQADEEREKNGSDDDDDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPASKPKVKEVMVKTLPVRSFPTMLKECSPKKDPKAPASVVASGGCPCTSSSTSIVASASSSSTPAQETICLDDSLDEDLSLPSASLDLVSEALAVINNGNKGPSVSSRLNVPTTKPRPGLREEKLASIMSKLPLATPKKLDSPQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSSQTHVSSSQAQAAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSQLLKTSEKPLMYRLPLSTPSPGNGSQGSHPLVSRTAPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLTSPKPSVSPKPSLSAKPSVSTKLISKSNPTPKPAVCPSSSSPNTLVAQSSHSTSNNPAHKQPSGMNISRQSPTLNLLPSNRTSGLPTTKTLQAPSKLTNSSSAGTVGKNSLSGIPVNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPTSASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQTVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTATSGSTSAALHHGLTQNLLKSLQPGTQHAATLPHSPLPTHLQQAFNDGGQSKGDTKLPRKPQ", "length": 1330 }, "evidence": [ { "id": "A0A8V0YAW5", "url": "https://omabrowser.org/oma/group/A0A8V0YAW5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B7L7-1", "protein_name": "Ubinuclein-2", "gene_name": "UBN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEPRRVAFISLSPVRRREAEFPGTEREPEYPREPPRLEPQPYREPARTEPPAPREVAPRSDAQPPPREKPLPQREVSRAEPPMSLQREPPRPEPPPPPLPQLHLQPPPPRESTSRAEPQPRPPRETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKPVYTEDPFNDDHQERQEVEMLAKKFEMKYGGKPRKHRRDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDTTDNQKHKPPKIPKIKEDDIEMKKRKRKEEGEKEKKPRKKVPKQLGVMALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESNPKTPLNFSTSSLNKPPSAAVALGNDVSDLNLTSADPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDAASNGSPLSESGGENGNTTQPTYASQVMPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARNQAKCAKFQTDEEREKNGSEEDDEEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPAPKPKVKECSPKKDQKTPASSVASVGGPSTSSSTSAVASTSSGSTPVQETICLDDSLDEELSFHPPALDLVSEALAVINNGNKGPPAGSRISMPTAKPRPGLREEKLASIMSKLPLATPKKLDSTQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSSSQTHVSSSSQAQVAASSHTLGTSEAQDASPLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSPLTKTSDKPLMYRLPLSTPPPGNGSQGSHSLVSRTVPSTTTSTNYLAKAMVSQISTQGFKSPFSMAASPKLASSPKPATSPKPLPSPKPSASPKPSQSAKPSVSTKLISKSNPTPKPTVSPSSSSPNALVAQSSHSSSNNPVHKQPSGMNISRQSPTLNLLPLNRTSGLPSTKNLQAPSKLTNSPSTGTVGKNSLSGIAMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPSSASGSSVVAASVQSTAGASLLANASPLTLMTSPLSVTNQNVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTTTSGSTSAAFHHSLTQNLLKGLQPGAQHAAALSHAPLPTHVQQTFNDGGQSKGDTKLPRKSQ", "length": 1330 }, "evidence": [ { "id": "A0A8V0YAW5", "url": "https://omabrowser.org/oma/group/A0A8V0YAW5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZU65-1", "protein_name": "Ubinuclein-2", "gene_name": "UBN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPRRVAFISLSPVRRREAEYPGPEREPEYPREPPRLEPQPYREPARAEPPAPREPAPRSDAQPPSREKPLPQREVSRAEPPMSLQREPPRPEPPPPFPPLPLQPPPPRESASRAEQPPRPPRETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKLIHTEDPFNDEHQERQEVEMLAKKFEMKYGGKPRKHRKDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDITDNQKHKPPKVPKIKEDDIEMKKRKRKEEGEKEKKPRKKVPKQLGVVALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESNPKVPVTLSTPSLNKPPCAAAALGNDVPDLNLSSGDPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDAASDGSPLSESGGENGTTTQPTYTSQVMPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQTDEEREKNGSEEDDDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPAPKPKVKEVMVKTLPLHSFPTMLKECSPKKDQKTPTSLVASVSGPPTSSSTAAIAAASSSSAPAQETICLDDSLDEDLSFHSPSLDLVSEALAVINNGNKGPPVGSRISMPTTKPRPGLREEKLASIMSKLPLATPKKLDSTQTTHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHTSSSSQTHVSSSSQAQIAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSSLIKTSDKPLMYRLPLSTPSPGNGSQGSHPLVSRTVPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLPSPKPSASPKPSLSAKPSVSTKLISKSNPTPKPTVSPSSSSPNALVAQGSHSSTNSPVHKQPSGMNISRQSPTLNLLPSSRTSGLPPTKNLQAPSKLTNSSSTGTVGKNSLSGIAMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPSTASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQNVTPFGMLGGLVPVTMPFQFPLEIFGFGTDTAGVTTTSGSTSAAFHHSLTQNLLKGLQPGGAQHAATLSHSPLPAHLQQAFHDGGQSKGDTKLPRKSQ", "length": 1347 }, "evidence": [ { "id": "A0A8V0YAW5", "url": "https://omabrowser.org/oma/group/A0A8V0YAW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80WC1-1", "protein_name": "Ubinuclein-2", "gene_name": "Ubn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPRRVAFISLSPVRRREADFAGAEREPPRLEPQPYREPARAEPAPRADAQPPARDKPLPQREVSRAEPPMALQREPPRPEPPPPPLPLQTPPPRESASRAEPPPRPPKETVRLELVLKDPTDESCVEFSYPELLLCGEQRKKLVHTEDPFTDEHKERQEVEMLAKKFEMKYGGKARKHRKDRLQDLIDIGFGYDETDPFIDNSEAYDELVPASLTTKYGGFYINTGTLQFRQASDTEEDDFTDNQKHKPPKVPKIKEDDIEVKKRKRKEEGEKEKKPRKKVPKQLGVVALNSHKSEKKKKRYKDSLSLAAMIRKFQKEKDALKKESTPKVPVTPSSSSLPKPPCVTTALGDDIPDLGLNSADPDLPIFVSTNEHELFQEAENALEMLDDFDFDRLLDATSDGSPLSESGGENGNTTHPTFPSQVVPKVVPTLPEGLPVLLEKRIEDLRVAAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVIRSGVYSHLEAFVPCNKETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQADEEREKNGSDDDDDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEVKPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPASKPKVKECSPKKDPKAPASVVASGGGPSTSSSTSIVASASSSSAPAQETICLDDSLDEDLSFPSASLDLVSEALAVINNGNKGPSVGSRLNVPTTKPRPGLREEKLASIMSKLPLATPKKLDSTQTAHSSSLIAGHTGPVPKKPQDLAHTGISSGLIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHASSSSQTHVSSSQAQAAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVVKLSNNPQLSCSSQLLKTSDKPLMYRLPLSTPSPGNGSQGPHPLVSRTAPSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSPKPLPSPKPSVSPKPSLSAKPSISTKQISKSNPAPKPAVCPSSSSPNTLVAQSSHSTSNNPVHKQPSGMNISRQSPTLNLLPSNRTSGLPTTKTLQAPSKLTNSSSTGTAGKNSLSGIPMNVPASRGSNLNSSGANRTSLSGGTGSGTQGATKPLSTPHRPTSASGSSVVTASVQSTAGASLLANASPLTLMTSPLSVTNQTVTPFGMLGGLVPVTMPFQFPLELLGFGTDTAGVTATSGSTSAALHHSLTQNLLKSLQPGAQHAAALPHSPLPAHLQQAFNDGGQSKGDTKLPRKPQ", "length": 1314 }, "evidence": [ { "id": "A0A8V0YAW5", "url": "https://omabrowser.org/oma/group/A0A8V0YAW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1114, "end_pos": 1116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1142, "end_pos": 1144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1196, "end_pos": 1198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YAW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5" }, { "id": "PF08729", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08729" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hpc2-related", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 224, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YAW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW5" }, { "id": "PF14075", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14075" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubinuclein middle", "eco_id": "ECO_0000259", "start_pos": 433, "end_pos": 647, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1052 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1034, "end_pos": 1036 }, { "start_pos": 1081, "end_pos": 1083 }, { "start_pos": 1095, "end_pos": 1097 }, { "start_pos": 1114, "end_pos": 1116 }, { "start_pos": 1142, "end_pos": 1144 }, { "start_pos": 1196, "end_pos": 1198 }, { "start_pos": 1213, "end_pos": 1215 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 614, "end_pos": 616 }, { "start_pos": 690, "end_pos": 692 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAW6-1", "uniprot_ac": "A0A8V0YAW6", "uniprot_id": "A0A8V0YAW6_CHICK", "mass": { "chemical_mass": 71237.0, "monoisotopic_mass": 71237.0 }, "refseq": { "ac": "XP_015132818", "name": "WD repeat-containing protein 70 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132818" }, "gene_names": [ { "name": "WDR70", "type": "recommended", "evidence": [ { "id": "A0A8V0YAW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6" } ] }, { "name": "WDR70", "type": "synonym", "evidence": [ { "id": "XP_015132818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132818" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 70", "type": "recommended", "evidence": [ { "id": "A0A8V0YAW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 70 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015132818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132818" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132818" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6", "locus": { "chromosome": "Z", "start_pos": 12253959, "end_pos": 12116629, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012861", "url": "https://www.ensembl.org/id/ENSGALG00010012861" } ] } } ], "crossref": [ { "id": "A0A8V0YAW6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "427444", "url": "https://www.ncbi.nlm.nih.gov/gene/427444", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAW6", "url": "https://www.orthodb.org/?gene=A0A8V0YAW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG72", "url": "https://www.orthodb.org/?gene=A0A8V0YG72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YG90", "url": "https://www.orthodb.org/?gene=A0A8V0YG90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJC0", "url": "https://www.orthodb.org/?gene=A0A8V0YJC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YP33", "url": "https://www.orthodb.org/?gene=A0A8V0YP33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16017:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16017:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015132818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132818", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YG90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YG90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YP33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YP33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPAAEGDAEMLTGPDPELAATMGFSGFGKKARTFDLEAMFEQTRRTAVERSRKVLEARAREQQDQAEKEFKSSCTDPSASASSATGAGSALKPRVTTCSESDDSSDEELTGPSKVLQASVQSSAGDDDDEEFIGPPLPPGFKDSDDDDTEDEDNNPIKKIPDSHEITLQHGTKTVSALGLDPSGARLITGGYDYDVKFWDFAGMDASLQAFRSLQPCECHQIKSLQYSSTGDVILVVSGNSQAKVLDRDGFPVMECIKGDQYIVDMTNTKGHTAMLNSGCWHPKIKEEFLTCSNDGTVRTWDVNNEKKHKSVFKPRSAQGKRVIPTTCTYSRDGKLIAAGCQDGSIQIWDRNMSVHTKFHCRQAHATGTDTSCLTFSYDGTALASRGGDDTLKIWDIRQFKKPLHSAERLSSFFPMTDCCFSPDDKILVTGTSVKKGGGSGKLFFFDRGTFQKLYEIEVTDASVVRCLWHPKLNQIMVGTGNGLAKVYYDPVKSQRGAKLCVVKTKRKEKQAETLTQDYIITPHALPMFREPRQRSTRKQLEKDRLDPMKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDSNPREAILRHAKEAEENPYWVAPAYAKTQPKTVFAEVEPEDDETDKPEWKKRKI", "length": 645, "header": "tr|A0A8V0YAW6-1|A0A8V0YAW6_CHICK Isoform 1 of WD repeat-containing protein 70 OS=Gallus gallus OX=9031 GN=WDR70 PE=3 SV=1 CANONICAL=A0A8V0YAW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6/entry#A0A8V0YAW6-1", "sequence": { "sequence": "MEPPAAEGDAEMLTGPDPELAATMGFSGFGKKARTFDLEAMFEQTRRTAVERSRKVLEARAREQQDQAEKEFKSSCTDPSASASSATGAGSALKPRVTTCSESDDSSDEELTGPSKVLQASVQSSAGDDDDEEFIGPPLPPGFKDSDDDDTEDEDNNPIKKIPDSHEITLQHGTKTVSALGLDPSGARLITGGYDYDVKFWDFAGMDASLQAFRSLQPCECHQIKSLQYSSTGDVILVVSGNSQAKVLDRDGFPVMECIKGDQYIVDMTNTKGHTAMLNSGCWHPKIKEEFLTCSNDGTVRTWDVNNEKKHKSVFKPRSAQGKRVIPTTCTYSRDGKLIAAGCQDGSIQIWDRNMSVHTKFHCRQAHATGTDTSCLTFSYDGTALASRGGDDTLKIWDIRQFKKPLHSAERLSSFFPMTDCCFSPDDKILVTGTSVKKGGGSGKLFFFDRGTFQKLYEIEVTDASVVRCLWHPKLNQIMVGTGNGLAKVYYDPVKSQRGAKLCVVKTKRKEKQAETLTQDYIITPHALPMFREPRQRSTRKQLEKDRLDPMKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDSNPREAILRHAKEAEENPYWVAPAYAKTQPKTVFAEVEPEDDETDKPEWKKRKI", "length": 645, "header": "tr|A0A8V0YAW6-1|A0A8V0YAW6_CHICK Isoform 1 of WD repeat-containing protein 70 OS=Gallus gallus OX=9031 GN=WDR70 PE=3 SV=1 CANONICAL=A0A8V0YAW6-1" }, "locus": { "chromosome": "Z", "start_pos": 12253100, "end_pos": 12117909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030860.1", "url": "https://www.ensembl.org/id/ENSGALT00010030860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017906.1", "url": "https://www.ensembl.org/id/ENSGALP00010017906.1" } ] } }, { "isoform_ac": "A0A8V0YG72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6/entry#A0A8V0YG72-1", "sequence": { "sequence": "MEPPAAEDAEMLTGPDPELAATMGFSGFGKKARTFDLEAMFEQTRRTAVERSRKVLEARAREQQDQAEKEFKSSCTDPSASASSATGAGSALKPRVTTCSESDDSSDEELTGPSKVLQASVQSSAGDDDDEEFIGPPLPPGFKDSDDDDTEDEDNNPIKKIPDSHEITLQHGTKTVSALGLDPSGARLITGGYDYDVKFWDFAGMDASLQAFRSLQPCECHQIKSLQYSSTGDVILVVSGNSQAKVLDRDGFPVMECIKGDQYIVDMTNTKGHTAMLNSGCWHPKIKEEFLTCSNDGTVRTWDVNNEKKHKSVFKPRSAQGKRVIPTTCTYSRDGKLIAAGCQDGSIQIWDRNMSVCILCIHNSYC", "length": 366, "header": "tr|A0A8V0YG72-1|A0A8V0YAW6_CHICK Computationally mapped isoform of WD repeat-containing protein 70 OS=Gallus gallus OX=9031 GN=WDR70 PE=3 SV=1 CANONICAL=A0A8V0YAW6-1" }, "locus": { "chromosome": "Z", "start_pos": 12196514, "end_pos": 12117909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030849.1", "url": "https://www.ensembl.org/id/ENSGALT00010030849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017900.1", "url": "https://www.ensembl.org/id/ENSGALP00010017900.1" } ] } }, { "isoform_ac": "A0A8V0YG90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6/entry#A0A8V0YG90-1", "sequence": { "sequence": "MDAEMLTGPDPELAATMGFSGFGKKARTFDLEAMFEQTRRTAVERSRKVLEARAREQQDQAEKEFKSSCTDPSASASSATGAGSALKPRVTTCSESDDSSDEELTGPSKVLQASVQSSAGDDDDEEFIGPPLPPGFKDSDDDDTEDEDNNPIKKIPDSHEITLQHGTKTVSALGLDPSGARLITGGYDYDVKFWDFAGMDASLQAFRSLQPCECHQIKSLQYSSTGDVILVVSGNSQAKVLDRDGFPVMECIKGDQYIVDMTNTKGHTAMLNSGCWHPKIKEEFLTCSNDGTVRTWDVNNEKKHKSVFKPRSAQGKRVIPTTCTYSRDGKLIAAGCQDGSIQIWDRNMSVHTKFHCRQAHATGTDTSCLTFSYDGTALASRGGDDTLKIWDIRQFKKPLHSAERLSSFFPMTDCCFSPDDKILVTGTSVKKGGGSGKLFFFDRGTFQKLYEIEVTDASVVRCLWHPKLNQIMVGTGNGLAKVYYDPVKSQRGAKLCVVKTKRKEKQAETLTQDYIITPHALPMFREPRQRSTRKQLEKDRLDPMKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDSNPREAILRHAKEAEENPYWVAPAYAKTQPKTVFAEVEPEDDETDKPEWKKRKI", "length": 638, "header": "tr|A0A8V0YG90-1|A0A8V0YAW6_CHICK Computationally mapped isoform of WD repeat-containing protein 70 OS=Gallus gallus OX=9031 GN=WDR70 PE=3 SV=1 CANONICAL=A0A8V0YAW6-1" }, "locus": { "chromosome": "Z", "start_pos": 12253100, "end_pos": 12117207, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030877.1", "url": "https://www.ensembl.org/id/ENSGALT00010030877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017920.1", "url": "https://www.ensembl.org/id/ENSGALP00010017920.1" } ] } }, { "isoform_ac": "A0A8V0YJC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6/entry#A0A8V0YJC0-1", "sequence": { "sequence": "MESFIDAEMLTGPDPELAATMGFSGFGKKARTFDLEAMFEQTRRTAVERSRKVLEARAREQQDQAEKEFKSSCTDPSASASSATGAGSALKPRVTTCSESDDSSDEELTGPSKVLQASVQSSAGDDDDEEFIGPPLPPGFKDSDDDDTEDEDNNPIKKIPDSHEITLQHGTKTVSALGLDPSGARLITGGYDYDVKFWDFAGMDASLQAFRSLQPCECHQIKSLQYSSTGDVILVVSGNSQAKVLDRDGFPVMECIKGDQYIVDMTNTKGHTAMLNSGCWHPKIKEEFLTCSNDGTVRTWDVNNEKKHKSVFKPRSAQGKRVIPTTCTYSRDGKLIAAGCQDGSIQIWDRNMSVHTKFHCRQAHATGTDTSCLTFSYDGTALASRGGDDTLKIWDIRQFKKPLHSAERLSSFFPMTDCCFSPDDKILVTGTSVKKGGGSGKLFFFDRGTFQKLYEIEVTDASVVRCLWHPKLNQIMVGTGNGLAKVYYDPVKSQRGAKLCVVKTKRKEKQAETLTQDYIITPHALPMFREPRQRSTRKQLEKDRLDPMKSHKPEPPVAGPGRGGRVGTHGGTLSSYIVKNIALDKTDDSNPREAILRHAKEAEENPYWVAPAYAKTQPKTVFAEVEPEDDETDKPEWKKRKI", "length": 642, "header": "tr|A0A8V0YJC0-1|A0A8V0YAW6_CHICK Computationally mapped isoform of WD repeat-containing protein 70 OS=Gallus gallus OX=9031 GN=WDR70 PE=3 SV=1 CANONICAL=A0A8V0YAW6-1" }, "locus": { "chromosome": "Z", "start_pos": 12253100, "end_pos": 12116821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030885.1", "url": "https://www.ensembl.org/id/ENSGALT00010030885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017929.1", "url": "https://www.ensembl.org/id/ENSGALP00010017929.1" } ] } }, { "isoform_ac": "A0A8V0YP33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6/entry#A0A8V0YP33-1", "sequence": { "sequence": "MEPPAAEDAEMLTGPDPELAATMGFSGFGKKARTFDLEAMFEQTRRTAVERSRKVLEARAREQQDQAEKEFKSSCTDPSASASSATGAGSALKPRVTTCSESDDSSDEELTGPSKVLQASVQSSAGDDDDEEFIGPPLPPGFKDSDDDDTEDEDNNPIKKIPDSHEITLQHGTKTVSALGLDPSGARLITGGYDYDVKFWDFAGMDASLQAFRSLQPCECHQIKSLQYSSTGDVILVVSGNSQAKVLDRDGFPVMECIKGDQYIVDMTNTKGHTAMLNSGCWHPKIKEEFLTCSNDGTVRTWDVNNEKKHKSVFKPRSAQGKRVIPTTCTYSRDGKLIAAGCQDGSIQIWDRNMSVHTKFHCRQAHATGTDTSCLTFSYDGTALASRGGDDTLKIWDIRQFKKPLHSAERLSSFFPMTDCCFSPDDKILVTGTSVKKGGGSGKLFFFDRGTFQKLYEIEVTDANAAKNSFCRSGTRG", "length": 477, "header": "tr|A0A8V0YP33-1|A0A8V0YAW6_CHICK Computationally mapped isoform of WD repeat-containing protein 70 OS=Gallus gallus OX=9031 GN=WDR70 PE=3 SV=1 CANONICAL=A0A8V0YAW6-1" }, "locus": { "chromosome": "Z", "start_pos": 12253060, "end_pos": 12117909, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030854.1", "url": "https://www.ensembl.org/id/ENSGALT00010030854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017902.1", "url": "https://www.ensembl.org/id/ENSGALP00010017902.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 354, "end_pos": 356 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YAZ6-1", "uniprot_ac": "A0A8V0YAZ6", "uniprot_id": "A0A8V0YAZ6_CHICK", "mass": { "chemical_mass": 38816.0, "monoisotopic_mass": 38816.0 }, "refseq": { "ac": "XP_422283", "name": "heme-binding protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422283" }, "gene_names": [ { "name": "HEBP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YAZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6" } ] }, { "name": "HEBP2", "type": "synonym", "evidence": [ { "id": "XP_422283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422283" } ] } ], "protein_names": [ { "name": "Heme binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YAZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6/entry#names_and_taxonomy" } ] }, { "name": "heme-binding protein 2", "type": "synonym", "evidence": [ { "id": "XP_422283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422283" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422283.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422283" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HEBP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YAZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YAZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "424441", "url": "https://www.ncbi.nlm.nih.gov/gene/424441", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424441", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424441", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YAZ6", "url": "https://www.orthodb.org/?gene=A0A8V0YAZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11220:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11220:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422283", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YAZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLAVYSQICTHHFTPGLKRKSSHSLTSPCDLSWRGVTLFFVQFFLLGARNPLLTQPEVGTAPWKQWKLHKGAKPLMEPHHTLDPMLPGEQEVELSAFVWKLSNETQSSGSPNSSPCSRAEAWAESERTKINTALEHLVGVRSSNSWDSLVAKTSGKMIKSFKQTFLSLDLQSPRWSSIETMAKDSELRQYETAKWVSTVIKGETQKEAMRQGFWKLFHYIQGKNEKEIKIDMTVPVTCLVKSGCADFKISFFVPFEHQDSPPQPTDSDVFVEERKAAAIFVRSFSGFASPDKYAEEAEALAKLLRNRGQPFHEDFFYTAGYDSPFKLFNRHNEVWYFRK", "length": 340, "header": "tr|A0A8V0YAZ6-1|A0A8V0YAZ6_CHICK Isoform 1 of Heme binding protein 2 OS=Gallus gallus OX=9031 GN=HEBP2 PE=1 SV=1 CANONICAL=A0A8V0YAZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YAZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6/entry#A0A8V0YAZ6-1", "sequence": { "sequence": "MVLAVYSQICTHHFTPGLKRKSSHSLTSPCDLSWRGVTLFFVQFFLLGARNPLLTQPEVGTAPWKQWKLHKGAKPLMEPHHTLDPMLPGEQEVELSAFVWKLSNETQSSGSPNSSPCSRAEAWAESERTKINTALEHLVGVRSSNSWDSLVAKTSGKMIKSFKQTFLSLDLQSPRWSSIETMAKDSELRQYETAKWVSTVIKGETQKEAMRQGFWKLFHYIQGKNEKEIKIDMTVPVTCLVKSGCADFKISFFVPFEHQDSPPQPTDSDVFVEERKAAAIFVRSFSGFASPDKYAEEAEALAKLLRNRGQPFHEDFFYTAGYDSPFKLFNRHNEVWYFRK", "length": 340, "header": "tr|A0A8V0YAZ6-1|A0A8V0YAZ6_CHICK Isoform 1 of Heme binding protein 2 OS=Gallus gallus OX=9031 GN=HEBP2 PE=1 SV=1 CANONICAL=A0A8V0YAZ6-1" }, "locus": { "chromosome": "8", "start_pos": 7423145, "end_pos": 7419753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027366.1", "url": "https://www.ensembl.org/id/ENSGALT00010027366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015620.1", "url": "https://www.ensembl.org/id/ENSGALP00010015620.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424441", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424441", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YAZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 266 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 113, "end_pos": 115 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB20-1", "uniprot_ac": "A0A8V0YB20", "uniprot_id": "A0A8V0YB20_CHICK", "mass": { "chemical_mass": 121902.0, "monoisotopic_mass": 121902.0 }, "refseq": {}, "gene_names": [ { "name": "SCAF4", "type": "recommended", "evidence": [ { "id": "A0A8V0YB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ] } ], "protein_names": [ { "name": "SR-related CTD associated factor 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCAF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20", "locus": { "chromosome": "1", "start_pos": 104755025, "end_pos": 104799463, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011797", "url": "https://www.ensembl.org/id/ENSGALG00010011797" } ] } } ], "crossref": [ { "id": "A0A8V0YB20", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB20", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17005", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17005", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB20", "url": "https://www.orthodb.org/?gene=A0A8V0YB20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJF6", "url": "https://www.orthodb.org/?gene=A0A8V0YJF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23140:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23140:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DESRHTFRQIILRLRDRLFSLMEMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSTAAPMTENATNNEGSPPPPAKVASEPSQVTANSVPTMPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPQKAQSPVIDNTVMAQVQAITAQLKTTASQPPEQKAAFPQPEQKTSFDKKLLDRFDYDDEPEAVEDSKKEDSAPSPSVSQPALTSLSFHAQAGWCSVPGGFAGEGIQQPVFPQLPNMDPFQQRMMGMQQDPMRHQVPLPPNGQMPGFGLLPTPQFPPMAQPVIPPTAPVQQTFQTPFPVQSESHMQKTHQQNMEVEQPPIQERKRHVSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPKSRSQERRERERERERRSKGLPQIKSETVSVCSTTLWVGQLDKRTTQQDVGSLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNFKVNQKSIKIAWALNKGIKPDYKQYWDVELGVTYIPWDKVKPEDLESFCEGGMLDNETLSPEWKGIPKKSENEVAQNGGAEATHNEPVSPIPKALPVPIPVPMPAPITVPPPQVPPHPSGPPVVGALQPPAFTAPLGIPPPGFAPGVPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSVPHTPAVNIPNSTAAGVNEDTTKDASVGNPIPTVVSGSRGNAETTDSSKIYATVPPPVAPTNVPAPVTQAIPLLGTQGVAPPPPAPVVGLQTPSTGLLGARPGLIPLQRPPGMPPPPMQRFPMMPPRHMPPHMMHRGPPPGPGGFGMPPPHGMKTPFPPPGHFVRPGGMPGSGGPSGPEENRDGRQFRNDRQTFTPNRDQERFGRRSFGNRVENDRERYGNRSDDRDHERLGNRDRREWGRRSPERDRHRDMEDRNRRSSGHRDRERDSRDRESRRDKEENRGKEKPEVTDRADGEKNHESHSGKMEDADVVSELPKGESEPSGVKPEEELTSEATSSVEQAEKDLSAVAEAPR", "length": 1099, "header": "tr|A0A8V0YB20-1|A0A8V0YB20_CHICK Isoform 1 of SR-related CTD associated factor 4 OS=Gallus gallus OX=9031 GN=SCAF4 PE=1 SV=1 CANONICAL=A0A8V0YB20-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20/entry#A0A8V0YB20-1", "sequence": { "sequence": "DESRHTFRQIILRLRDRLFSLMEMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSTAAPMTENATNNEGSPPPPAKVASEPSQVTANSVPTMPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPQKAQSPVIDNTVMAQVQAITAQLKTTASQPPEQKAAFPQPEQKTSFDKKLLDRFDYDDEPEAVEDSKKEDSAPSPSVSQPALTSLSFHAQAGWCSVPGGFAGEGIQQPVFPQLPNMDPFQQRMMGMQQDPMRHQVPLPPNGQMPGFGLLPTPQFPPMAQPVIPPTAPVQQTFQTPFPVQSESHMQKTHQQNMEVEQPPIQERKRHVSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPKSRSQERRERERERERRSKGLPQIKSETVSVCSTTLWVGQLDKRTTQQDVGSLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNFKVNQKSIKIAWALNKGIKPDYKQYWDVELGVTYIPWDKVKPEDLESFCEGGMLDNETLSPEWKGIPKKSENEVAQNGGAEATHNEPVSPIPKALPVPIPVPMPAPITVPPPQVPPHPSGPPVVGALQPPAFTAPLGIPPPGFAPGVPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSVPHTPAVNIPNSTAAGVNEDTTKDASVGNPIPTVVSGSRGNAETTDSSKIYATVPPPVAPTNVPAPVTQAIPLLGTQGVAPPPPAPVVGLQTPSTGLLGARPGLIPLQRPPGMPPPPMQRFPMMPPRHMPPHMMHRGPPPGPGGFGMPPPHGMKTPFPPPGHFVRPGGMPGSGGPSGPEENRDGRQFRNDRQTFTPNRDQERFGRRSFGNRVENDRERYGNRSDDRDHERLGNRDRREWGRRSPERDRHRDMEDRNRRSSGHRDRERDSRDRESRRDKEENRGKEKPEVTDRADGEKNHESHSGKMEDADVVSELPKGESEPSGVKPEEELTSEATSSVEQAEKDLSAVAEAPR", "length": 1099, "header": "tr|A0A8V0YB20-1|A0A8V0YB20_CHICK Isoform 1 of SR-related CTD associated factor 4 OS=Gallus gallus OX=9031 GN=SCAF4 PE=1 SV=1 CANONICAL=A0A8V0YB20-1" }, "locus": { "chromosome": "1", "start_pos": 104788064, "end_pos": 104755392, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028210.1", "url": "https://www.ensembl.org/id/ENSGALT00010028210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016167.1", "url": "https://www.ensembl.org/id/ENSGALP00010016167.1" } ] } }, { "isoform_ac": "A0A8V0YJF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20/entry#A0A8V0YJF6-1", "sequence": { "sequence": "MEAVNAFNQELFSLMEMKPPISRAKMILITKAAIKAIKLYKHVVQIVEKFIKKCKPEYKVPGLYVIDSIVRQSRHQFGTDKDVFGPRFSKNITATFQYLYLCPSEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSTAAPMTENATNNEGSPPPPAKVASEPSQVTANSVPTMPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPQKAQSPVIDNTVMAQVQAITAQLKTTASQPPEQKAAFPQPEQKTSFDKKLLDRFDYDDEPEAVEDSKKEDSAPSPSVSQPAFGFAGEGIQQPVFPQLPNMDPFQQRMMGMQQDPMRHQVPLPPNGQMPGFGLLPTPQFPPMAQPVIPPTAPVQQTFQTPFPVQSESHMQKTHQQNMEVEQPPIQERKRHVSDNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPKSRSQERRERERERERRSKGLPQIKSETVSVCSTTLWVGQLDKRTTQQDVGSLLEEFGPIESINMIPPRGCAYIVMVHRQDAYRALQKLSRGNFKVNQKSIKIAWALNKGIKPDYKQYWDVELGVTYIPWDKVKPEDLESFCEGGMLDNETLSPEWKGIPKKSENEVAQNGGAEATHNEPVSPIPKALPVPIPVPMPAPITVPPPQVPPHPSGPPVVGALQPPAFTAPLGIPPPGFAPGVPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSVPHTPAVNIPNSAGVNEDTTKDASVGNPIPTVVSGSRGNAETTDSSKIYATVPPPVAPTNVPAPVTQAIPLLGTQGVAPPPPAPVVGLQTPSTGLLGARPGLIPLQRPPGMPPPPMQRFPMMPPRHMPPHMMHRGPPPGPGGFGMPPPHGMKTPFPPPGHFVRPGGMPGSGGPSGPEENRDGRQFRNDRQTFTPNRDQERFGRRSFGNRVENDRERYGNRSDDRDHERLGNRDRREWGRRSPERDRHRDMEDRNRRSSGHRDRERDSRDRESRRDKEENRGKEKPEVTDRADGEKNHESHSGKMEDADVVSELPKGESEPSGVKPEEELTSEATSSVEQAEKDLSAVAEAPR", "length": 1074, "header": "tr|A0A8V0YJF6-1|A0A8V0YB20_CHICK Computationally mapped isoform of SR-related CTD associated factor 4 OS=Gallus gallus OX=9031 GN=SCAF4 PE=1 SV=1 CANONICAL=A0A8V0YB20-1" }, "locus": { "chromosome": "1", "start_pos": 104799230, "end_pos": 104755392, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028228.1", "url": "https://www.ensembl.org/id/ENSGALT00010028228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016174.1", "url": "https://www.ensembl.org/id/ENSGALP00010016174.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 741, "start_aa": "Thr", "end_pos": 741, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr741", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain phosphoserine binding", "id": "GO:1990269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ], "pmid": "" }, { "name": "negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled", "id": "GO:2000805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" }, { "id": "PS51391", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 146, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB20" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 503, "end_pos": 577, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 382, 741 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 618, "end_pos": 620 }, { "start_pos": 756, "end_pos": 758 }, { "start_pos": 966, "end_pos": 968 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB38-1", "uniprot_ac": "A0A8V0YB38", "uniprot_id": "A0A8V0YB38_CHICK", "mass": { "chemical_mass": 54363.0, "monoisotopic_mass": 54363.0 }, "refseq": { "ac": "XP_040503102", "name": "protein FAM114A2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503102" }, "gene_names": [ { "name": "FAM114A2", "type": "recommended", "evidence": [ { "id": "A0A8V0YB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB38" } ] }, { "name": "FAM114A2", "type": "synonym", "evidence": [ { "id": "XP_040503102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503102" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 114 member A2", "type": "synonym", "evidence": [ { "id": "A0A8V0YB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB38/entry#names_and_taxonomy" } ] }, { "name": "protein FAM114A2", "type": "synonym", "evidence": [ { "id": "XP_040503102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503102" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503102" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB38" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM114A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB38", "locus": { "chromosome": "13", "start_pos": 11888155, "end_pos": 11878321, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012898", "url": "https://www.ensembl.org/id/ENSGALG00010012898" } ] } } ], "crossref": [ { "id": "A0A8V0YB38", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB38", "database": "AlphaFoldDB", "categories": [] }, { "id": "416262", "url": "https://www.ncbi.nlm.nih.gov/gene/416262", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416262", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416262", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTFFAEM", "url": "https://omabrowser.org/oma/group/NTFFAEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB38", "url": "https://www.orthodb.org/?gene=A0A8V0YB38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12842:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12842:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503102", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEEDNGENLKGETSHEDENEQKVEELGSTESNEEREPVPVTRKRPEPKAPSQSAGTETPTAETSKVSEPPASQSGWGYWGSWGKSLLSTASATVATVGQGISNVIEKAETTLGIPSPSEISSETRDATRGSENPDANSADATGDGSSFPIAGAFGVLSTISTAVQSTGKSVITGGLDALEFIGKKTMDVIAEGDPGFKKTKGLMNRTSTLSQVLREAKEKEEQQTATEVTMTTEKKAHYGLLFDEFQGLSHLEALEMLSRECESKVKLVLNALSGEELETVKEEMEQLNEAFSLAEFFEEEEEEKKGDEEFTKEVTELFAELRISTKPDKLIMVRTSAHDWIAQFNSSLPKEEKESEENEEVEPGGGDHDVKKSVEDIHAFAIRSLAELTAYSIESFHRTAALFLHGQKQEVTATDRAKSLSQVTIVLCKELSSFSKEFTTCLTIAGVKEKADVLNPLITGVFLEASNSASYIQDAFQLLLPVLQLSLIEARTELSQQ", "length": 499, "header": "tr|A0A8V0YB38-1|A0A8V0YB38_CHICK Isoform 1 of Family with sequence similarity 114 member A2 OS=Gallus gallus OX=9031 GN=FAM114A2 PE=1 SV=1 CANONICAL=A0A8V0YB38-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB38/entry#A0A8V0YB38-1", "sequence": { "sequence": "MSEEDNGENLKGETSHEDENEQKVEELGSTESNEEREPVPVTRKRPEPKAPSQSAGTETPTAETSKVSEPPASQSGWGYWGSWGKSLLSTASATVATVGQGISNVIEKAETTLGIPSPSEISSETRDATRGSENPDANSADATGDGSSFPIAGAFGVLSTISTAVQSTGKSVITGGLDALEFIGKKTMDVIAEGDPGFKKTKGLMNRTSTLSQVLREAKEKEEQQTATEVTMTTEKKAHYGLLFDEFQGLSHLEALEMLSRECESKVKLVLNALSGEELETVKEEMEQLNEAFSLAEFFEEEEEEKKGDEEFTKEVTELFAELRISTKPDKLIMVRTSAHDWIAQFNSSLPKEEKESEENEEVEPGGGDHDVKKSVEDIHAFAIRSLAELTAYSIESFHRTAALFLHGQKQEVTATDRAKSLSQVTIVLCKELSSFSKEFTTCLTIAGVKEKADVLNPLITGVFLEASNSASYIQDAFQLLLPVLQLSLIEARTELSQQ", "length": 499, "header": "tr|A0A8V0YB38-1|A0A8V0YB38_CHICK Isoform 1 of Family with sequence similarity 114 member A2 OS=Gallus gallus OX=9031 GN=FAM114A2 PE=1 SV=1 CANONICAL=A0A8V0YB38-1" }, "locus": { "chromosome": "13", "start_pos": 11887231, "end_pos": 11879212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030954.1", "url": "https://www.ensembl.org/id/ENSGALT00010030954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017986.1", "url": "https://www.ensembl.org/id/ENSGALP00010017986.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416262", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416262", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YX33-1", "protein_name": "Protein FAM114A2", "gene_name": "fam114a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDNEDSSSDQTEKSVDQEPTAAAPPHRDETDGSDVAPTRKTRRRPEQKLPAEEQENPETQQTTTTTSASDASTETTVSQGGWGYWGSWGKSILSTATATVATVGQGLTQVIEKAESSLGIPSPEELKAQVEEEEKNDDSASSEADRDESEKTYGMGGAMGMISSSSMGMLSSLTTVVQSTSKTVISGGLDALEFIGKKTMDVIAEGDPGFKKTKGLMNRNSTLSQVLREAKECEEQQKAENATSEPNKKAHYGMLFDEFQGLSHLEALEILSRESEAKVKSVLTTLSGEELTKLREDLQNIKEPFSLMEFDDELEDDTKCDDGEDFVKELTDVLKGLQISTSADKLSKARKNAFNHITNMKLRSENIEKEKEDKEEGEGEKEERQKEKNTETAETEYTVEDAHLSAITSLAEFTARSIEQFHKTAEMLLYSNTEGAAAPEQAKILSQVTIVICKEVSLLSKKFTSCLTTIGANEKGEVLNPLITSVFLEASNSASYIQDAFQLLLPVLEVSHIQRTVES", "length": 520 }, "evidence": [ { "id": "A0A8V0YB38", "url": "https://omabrowser.org/oma/group/A0A8V0YB38/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LAK6-1", "protein_name": "Family with sequence similarity 114, member A2", "gene_name": "Fam114a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGDAAVMADKDATETPAVTEAASILKDENCEPVEKPENKCQPAVSTRKRPETRPSSDLEASELPAQQETASKDASQTGWGYWGSWGKSLLSSASATVATVGQGISNVIEKAETSLGIPSPTEISAEVKQAAGETSASENGSLLVSGPFGMLSTISTAVQSTGKSVISGGLDALEFIGKKTMDVIAEGDPGFKRTKGLMIRNSTLSQVLREAKDKEEQWPSNEVTMETDKKTHYGLLFDEFQGLSHLEALEMLSRESEIKVKSILSSLSGEELQTTRLELEQLKEAFSLAEFCEEEEEERQGDEDFTKEITELIAQLHVSSRPEKLARARNTAYEWIRTSLAKPVAEKEEGEKQLEAENTEEAQKHSIEDIHAFAIRSLAELTACSIELFHKTAALVLHGQKQEVTALERSQTLSQMTVMLCKDLASLSKEFTTCLTTAGVKEKADVLNPLITAVFLEASNSASYIQDAFQLLLPVLQISLIENKTESPDVSHQPRDL", "length": 499 }, "evidence": [ { "id": "A0A8V0YB38", "url": "https://omabrowser.org/oma/group/A0A8V0YB38/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L703-1", "protein_name": "Family with sequence similarity 114 member A2", "gene_name": "FAM114A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSDKDDIETPVVTEAAPILEDENCEPAKNSGSLDLSAKPESKSEPVVSTRKRPEFKHSSDLETSEVLPVQASEAAGKEAVSKDVPQTGWGYWGSWGKSLLSSASATVATVGQGISNVIERAETSLGIPSPSDISTEVQYAAGETNAKESENSSPVSGPFGVFSTISTAVQSTGKSVISGGLDALEFIGKKTMDVIAEGDPGFKRTKGLMNRTSTLSQVLREVKEKEELWTSNEVTIETDKKTHYGLLFDEFQGLSHLEALEMLSRESEIKVKSILNSLSGEELETLKLELEQLKEAFSLAEFCEEEEEETKGDEDFTKEITELFSQLHVSSKPEKLARARNTAYEWISTSLAKPLEKKEEGEKQLEAEEAEQISNSSIEDIHAFAIRSLAELTACSIELFHKIAALVLHGRKQEVSAIERSRALSQMTVLLCKELSSLSKEFTTCLTTAGASNSASYIQDAFQLLLPVLEISLIENKTELPEA", "length": 483 }, "evidence": [ { "id": "A0A8V0YB38", "url": "https://omabrowser.org/oma/group/A0A8V0YB38/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VE88-1", "protein_name": "Protein FAM114A2", "gene_name": "Fam114a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDKDPPESPVVTGVASTLKDENCEPVEKPEDKSQPVVSTRKRPETKPSSDLEASALPAQVSLAVAKETASKDVPQTGWGYWGSWGKSLLSSASATVATVGQGISNVIEKAETSLGIPSPTEISAEVKQAAGEKNAGENGSLLVAAPFGMLSTISTAVQSTGKSVISGGLDALEFIGKKTMDVIAEGDPGFKRTKGLMNRTSTLSQVLREAKDKEEQRPSNEVTMETDKKTHYGLLFDEFQGLSHLEALEMLSRESEIKVKSILSSLSGEELQTTRLELEQLKEVFSLAEFCEEEEEERQGDDNFTKEITDLFAQLHVSSRPEKLARARNTAYKWIRTSLARPVAEKEEGEKESEAGNTEEAQKHSIEDIHAFAIRSLAELTACSIELFHKTAALVLHGQKQEVTALERSQTLSQMTVMLCKDLASLSKEFTTCLTTAGVREKADVLNPVITAVFLEASNSASYIQDAFQLLLPVLQISLIESKTESSTCEPQSRDL", "length": 497 }, "evidence": [ { "id": "A0A8V0YB38", "url": "https://omabrowser.org/oma/group/A0A8V0YB38/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRY5-1", "protein_name": "Protein FAM114A2", "gene_name": "FAM114A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDKDDIETPLLTEAAPILEDGNCEPAKNSESVDQGAKPESKSEPVVSTRKRPETKPSSDLETSKVLPIQDNVSKDVPQTRWGYWGSWGKSILSSASATVATVGQGISNVIEKAETSLGIPGPSEISTEVKYVAGETNAKENENSSPVAGAFGVFSTISTAVQSTGKSVISGGLDALEFIGKKTMDVIAEGDPGFKRTKGLMNRNATLSQVLREAKEKEEIRTSNEVTVETDKKTHYGLLFDEFQGLSHLEALEMLSQESEIKVKSILNSLSGEELETLKVELEQLKETFSLAEFCEEEEEEKKGDEDFTKDITELFSQLHVSSKPEKLARARNTAHEWIRKSLTKPLAENEEGEKQSEAENTEQVNKNSIEDIHAFAIRSLAELTACSIELFHKTAALVLHGRKQEVTAIERSQTLSQMTIVLCKELSSLSKEFTTCLTTAGVKEMADVLNPLITAVFLEASNSASYIQDAFQLLLPVLEISLIENKIESHRHELQGQKPLLEH", "length": 505 }, "evidence": [ { "id": "A0A8V0YB38", "url": "https://omabrowser.org/oma/group/A0A8V0YB38/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VF39-1", "protein_name": "Protein FAM114A2", "gene_name": "Fam114A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKNPKKEEDGGNDWAQSDEDDNWDDWGDDDDKFVHVEKEQQPQEKVSSRNDAKGTAENQEKLETPRISAPATASATSSSWGLWGGKLSSVLTTATEGLGTITTQVNQGLNQIIGVPDPEELARINVAEKAEKAAKAPPEENVDDEKESSAAFGLDFVTNLGSKVLNTGLDTLEGIGKKTMTILQDNDPKLMNKRKLLGLEANSPNLSAVLLEAKKEADQMEQSLQQLQLKRQKAQLRFEILFENYCGLVHFEALEILSKESRLKLDTLLDAVSGNARAELQETINEVKELIELEDLDVESEGDYEAEELSERLAATIKDAELGIQFDDIANHWTQSLSWLTSEEATAADLEQAYAKSIHALSEACALEMCKLHKIAELLLVKPHHSTANEVDGVVNLCQQFNGHLQGLSHRFAAVLSGKSETEESKGRVSTFFSEMLSAVQFIEKAYKLFTPILQMGAV", "length": 460 }, "evidence": [ { "id": "A0A8V0YB38", "url": "https://omabrowser.org/oma/group/A0A8V0YB38/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB50-1", "uniprot_ac": "A0A8V0YB50", "uniprot_id": "A0A8V0YB50_CHICK", "mass": { "chemical_mass": 134657.0, "monoisotopic_mass": 134657.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ligand dependent nuclear receptor corepressor like", "type": "synonym", "evidence": [ { "id": "A0A8V0YB50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB50/entry#names_and_taxonomy" } ] } ], "function": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF15090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YB50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNCHTKQVCFPVHQTESFKLPLPNFQTSSDFLVLSEDSAFAANQTKSAKTQDFATLKETDQIPLHGESNRTPGRTKRNIVPPGWYSVYVTNNIVFRKSSDAKKSVECLEKMQIDEDVHAERCCDINISKIVRDTNLQVVVERLEDTINLAKKASNSWLNSYKISQKVKDNAYEQVMNPLARRDFPFSVGETGCTGQSFLPHSHLSNSNKNKTVCVTSKQEMFIDQEINDSLLKSLSIDLSTSSNEALHATSDARELPSSLSYSSPVKLMFVSEVNSSEGIKYTLTSATTSSKGSTDICSFQGYTSTVLDKQTTENLSHAICVSDFENSAKEESSCVCAEAITSSCAVGQTNLNDSKQNEVVEKPSNSGDSVLKRKPGRPKKIGPQVVKQVKRPIGRPPKPKVDVTERRECRAELNSDGKSTKSDASVMEEVNSNKNITVTVVFGRSRRTKRHVSEGNLNVITTLPREQVDFSFANDHSKARRTAETENALTEIVKALQNSSTENEVSGYDYVRPIKSNLASPHPCSNIIRPVKKPLTTIRKPGRPAKVKISGISVTVNRVSPQERKVSISNCLPPLQQQNLLEKNISQERNNQLCNNMSQVKSVQKDSREDGSNSVTTTVSRKREIPLRHSVRDRKPSLHFLHSLASSSAFTCRSALLHKSYKLHLRKAKDQKEKRRQSNQSITSTDTSEMRNSGNSKMNLEDGDFGPINDVSSDPIFSSKPSLRWWATSASNDTLMEELNNRFEQITNTWLRVGGNEFDKCVCENRDPTEQDCNSEMSNPLDSCLVEIETSPIKMLFQKKCNMNELCTWFMQTTETQSLSLVRKANARNPLEVVSTREIKMENKQSDLSTCLFRKHFKKFALSSPSKPAGKLQILHNMVRSPVLSMKSNFTLARLKRNEFKKLQNDRWGQTKKKLYSQAPGGWKSKKKNLQFFCQSQLFKSASGESSDGMPVLQEKNTVEIQPTQTLVESQSSLLPTENEARDAFVQQMMGSSDFNPHPSLANILKSHTETNGTICCQQNVRKGQSQDKLFPNTWKAKTFKDCRIFLRKLSHVEQHNSFKLNNVIYSPEAVASKSHQAYLEEKRQPLLRSHSTKQNALKKQENEMETPKGSNSSKVTERLDDQFHSRELSSGVSHDDNPAGSSEVLIRINKRKSPQWETTDTNVRKRHKRQSYNSGQMAAYYPKCQVGKFLFPPSP", "length": 1197, "header": "tr|A0A8V0YB50-1|A0A8V0YB50_CHICK Isoform 1 of Ligand dependent nuclear receptor corepressor like OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YB50-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB50/entry#A0A8V0YB50-1", "sequence": { "sequence": "MNCHTKQVCFPVHQTESFKLPLPNFQTSSDFLVLSEDSAFAANQTKSAKTQDFATLKETDQIPLHGESNRTPGRTKRNIVPPGWYSVYVTNNIVFRKSSDAKKSVECLEKMQIDEDVHAERCCDINISKIVRDTNLQVVVERLEDTINLAKKASNSWLNSYKISQKVKDNAYEQVMNPLARRDFPFSVGETGCTGQSFLPHSHLSNSNKNKTVCVTSKQEMFIDQEINDSLLKSLSIDLSTSSNEALHATSDARELPSSLSYSSPVKLMFVSEVNSSEGIKYTLTSATTSSKGSTDICSFQGYTSTVLDKQTTENLSHAICVSDFENSAKEESSCVCAEAITSSCAVGQTNLNDSKQNEVVEKPSNSGDSVLKRKPGRPKKIGPQVVKQVKRPIGRPPKPKVDVTERRECRAELNSDGKSTKSDASVMEEVNSNKNITVTVVFGRSRRTKRHVSEGNLNVITTLPREQVDFSFANDHSKARRTAETENALTEIVKALQNSSTENEVSGYDYVRPIKSNLASPHPCSNIIRPVKKPLTTIRKPGRPAKVKISGISVTVNRVSPQERKVSISNCLPPLQQQNLLEKNISQERNNQLCNNMSQVKSVQKDSREDGSNSVTTTVSRKREIPLRHSVRDRKPSLHFLHSLASSSAFTCRSALLHKSYKLHLRKAKDQKEKRRQSNQSITSTDTSEMRNSGNSKMNLEDGDFGPINDVSSDPIFSSKPSLRWWATSASNDTLMEELNNRFEQITNTWLRVGGNEFDKCVCENRDPTEQDCNSEMSNPLDSCLVEIETSPIKMLFQKKCNMNELCTWFMQTTETQSLSLVRKANARNPLEVVSTREIKMENKQSDLSTCLFRKHFKKFALSSPSKPAGKLQILHNMVRSPVLSMKSNFTLARLKRNEFKKLQNDRWGQTKKKLYSQAPGGWKSKKKNLQFFCQSQLFKSASGESSDGMPVLQEKNTVEIQPTQTLVESQSSLLPTENEARDAFVQQMMGSSDFNPHPSLANILKSHTETNGTICCQQNVRKGQSQDKLFPNTWKAKTFKDCRIFLRKLSHVEQHNSFKLNNVIYSPEAVASKSHQAYLEEKRQPLLRSHSTKQNALKKQENEMETPKGSNSSKVTERLDDQFHSRELSSGVSHDDNPAGSSEVLIRINKRKSPQWETTDTNVRKRHKRQSYNSGQMAAYYPKCQVGKFLFPPSP", "length": 1197, "header": "tr|A0A8V0YB50-1|A0A8V0YB50_CHICK Isoform 1 of Ligand dependent nuclear receptor corepressor like OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YB50-1" }, "locus": { "chromosome": "4", "start_pos": 75412552, "end_pos": 75408962, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026241.1", "url": "https://www.ensembl.org/id/ENSGALT00010026241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014865.1", "url": "https://www.ensembl.org/id/ENSGALP00010014865.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1113, "end_pos": 1115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB54-1", "uniprot_ac": "A0A8V0YB54", "uniprot_id": "A0A8V0YB54_CHICK", "mass": { "chemical_mass": 33994.0, "monoisotopic_mass": 33994.0 }, "refseq": { "ac": "XP_004937136", "name": "tubulin polyglutamylase complex subunit 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937136" }, "gene_names": [ { "name": "TPGS2", "type": "recommended", "evidence": [ { "id": "A0A8V0YB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54" } ] }, { "name": "TPGS2", "type": "synonym", "evidence": [ { "id": "XP_004937136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937136" } ] } ], "protein_names": [ { "name": "Tubulin polyglutamylase complex subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54/entry#names_and_taxonomy" } ] }, { "name": "tubulin polyglutamylase complex subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937136" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937136" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPGS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54", "locus": { "chromosome": "Z", "start_pos": 7574252, "end_pos": 7550043, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011458", "url": "https://www.ensembl.org/id/ENSGALG00010011458" } ] } } ], "crossref": [ { "id": "A0A8V0YB54", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB54", "database": "AlphaFoldDB", "categories": [] }, { "id": "426891", "url": "https://www.ncbi.nlm.nih.gov/gene/426891", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426891", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426891", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WQFLAET", "url": "https://omabrowser.org/oma/group/WQFLAET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB54", "url": "https://www.orthodb.org/?gene=A0A8V0YB54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31854:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31854:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004937136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937136", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEKPSAGIRPHLDKLTLGVTRILETSPGVSDVTLVEKEPADRHAIISWEQKNACILPEDLKNFYLMTDGFQMTWSVKIDDTPMPLGSMVINSISKLCRLGGSSMYTVPNAPSLADLEDDTDEEGKVLLTGNEDKPEKPHFDSRSLIFELDPCNGNGKVCLVYRHTKPVVSPDTEIWFLDRALYWHFLTKTFTAYYRLLITHLGLPQWQYAFTSYGVSPQAKQWFNMYKPITINTTLLSEEADSFVNKLDPSKIFKSKNKTPVMKKKQPSQPAGVQKSNTSMPSTKTSSLAGNSSRKRDPQI", "length": 302, "header": "tr|A0A8V0YB54-1|A0A8V0YB54_CHICK Isoform 1 of Tubulin polyglutamylase complex subunit 2 OS=Gallus gallus OX=9031 GN=TPGS2 PE=4 SV=1 CANONICAL=A0A8V0YB54-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54/entry#A0A8V0YB54-1", "sequence": { "sequence": "MEEKPSAGIRPHLDKLTLGVTRILETSPGVSDVTLVEKEPADRHAIISWEQKNACILPEDLKNFYLMTDGFQMTWSVKIDDTPMPLGSMVINSISKLCRLGGSSMYTVPNAPSLADLEDDTDEEGKVLLTGNEDKPEKPHFDSRSLIFELDPCNGNGKVCLVYRHTKPVVSPDTEIWFLDRALYWHFLTKTFTAYYRLLITHLGLPQWQYAFTSYGVSPQAKQWFNMYKPITINTTLLSEEADSFVNKLDPSKIFKSKNKTPVMKKKQPSQPAGVQKSNTSMPSTKTSSLAGNSSRKRDPQI", "length": 302, "header": "tr|A0A8V0YB54-1|A0A8V0YB54_CHICK Isoform 1 of Tubulin polyglutamylase complex subunit 2 OS=Gallus gallus OX=9031 GN=TPGS2 PE=4 SV=1 CANONICAL=A0A8V0YB54-1" }, "locus": { "chromosome": "Z", "start_pos": 7572732, "end_pos": 7550346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027423.1", "url": "https://www.ensembl.org/id/ENSGALT00010027423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015677.1", "url": "https://www.ensembl.org/id/ENSGALP00010015677.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426891", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426891", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LA68-1", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "TPGS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEETPPPLLGSSKPHLEKLTLGITRILESSPGVTEVTIVEKVPAERHMISSWEQKNNCLLPEDLKNFYLMTNGFHMTWSVKLDEHTIPLGSMAINSISKLTQLNQSSMYSLPNAPTLADLEDDTQEAGENQPEKPHFDSRSVIFELDPCNGNGKVCLVYKRGKPALAQDSEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFNMYKPITYNTNLLTEETDSFVNKLDPSKVFKSKNKTLIPKKKGPPQPAGGQKGPSGPPSTSKSSSGSGNPVRK", "length": 294 }, "evidence": [ { "id": "A0A8V0YB54", "url": "https://omabrowser.org/oma/group/A0A8V0YB54/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66JT5-1", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "Tpgs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEETTPPLQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHVISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDEHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDTQEGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFIAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEESDNFANKLDPSKVFKSKNKILIPKKKGPVPPASGQKGPGPLPPPTSKPTTGSGNPVRK", "length": 296 }, "evidence": [ { "id": "A0A8V0YB54", "url": "https://omabrowser.org/oma/group/A0A8V0YB54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q68CL5-2", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "TPGS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCVMPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLADLEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETDSFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK", "length": 300 }, "evidence": [ { "id": "A0A8V0YB54", "url": "https://omabrowser.org/oma/group/A0A8V0YB54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VTS1-1", "protein_name": "Knr4/Smi1-like domain-containing protein", "gene_name": "Dmel\\CG6931", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMNKKLSPEDAFYENLTLGLIRTLSNVPRVCNVTLERRQPLNACQLVNWEQRHCVYLPEDMKKFYLSSDGFILNWSYQYAPNDIRRVGHIHFPHLLQVTLLRENIETTSSHSSNSTAVPNSNSDVVGAAGSSQSLPAPIATGKDKWGNATPIITAKSKIFEINNVNEVAKVCMLYESTSSNNPKFYLLELSTLSWQFLADTFSEYLRMAIAHLGLPYWELCFSTCGLPSWTEQLFLLLAPHLLEEHEPRRGRVLNPACEHPYNIIDPNIFRGKPKSVAKATATSTKQNHK", "length": 290 }, "evidence": [ { "id": "A0A8V0YB54", "url": "https://omabrowser.org/oma/group/A0A8V0YB54/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB54" }, { "id": "SM00860", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00860" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Knr4/Smi1-like", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 190, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 293, "end_pos": 295 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB62-1", "uniprot_ac": "A0A8V0YB62", "uniprot_id": "A0A8V0YB62_CHICK", "mass": { "chemical_mass": 23541.0, "monoisotopic_mass": 23541.0 }, "refseq": { "ac": "NP_001186559", "name": "calcium-activated potassium channel subunit beta-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" }, "gene_names": [ { "name": "KCNMB4", "type": "recommended", "evidence": [ { "id": "A0A8V0YB62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62" } ] }, { "name": "KCNMB4", "type": "synonym", "evidence": [ { "id": "NP_001186559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" } ] } ], "protein_names": [ { "name": "Potassium calcium-activated channel subfamily M regulatory beta subunit 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YB62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62/entry#names_and_taxonomy" } ] }, { "name": "calcium-activated potassium channel beta 4 subunit", "type": "synonym", "evidence": [ { "id": "NP_001186559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" } ] }, { "name": "calcium-activated potassium channel subunit beta-4", "type": "synonym", "evidence": [ { "id": "NP_001186559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" } ] }, { "name": "potassium channel subfamily M regulatory beta subunit 4", "type": "synonym", "evidence": [ { "id": "NP_001186559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" } ] }, { "name": "potassium large conductance calcium-activated channel, subfamily M, beta member 4", "type": "synonym", "evidence": [ { "id": "NP_001186559", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR354309.1, BX931406.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_001186559.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186559", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" } ] }, { "annotation": "The beta4-subunit in particular is responsible for the large-conductance potassium BK channel's increased responsiveness to divalent calcium ions (Ca2+) at a hair cell's operating voltage.", "evidence": [ { "database": "RefSeq", "id": "NP_001186559", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" }, { "database": "PubMed", "id": "21178105", "url": "https://glygen.org/publication/PubMed/21178105" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNMB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62", "locus": { "chromosome": "1", "start_pos": 35955882, "end_pos": 35944896, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011841", "url": "https://www.ensembl.org/id/ENSGALG00010011841" } ] } } ], "crossref": [ { "id": "A0A8V0YB62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB62", "database": "AlphaFoldDB", "categories": [] }, { "id": "417852", "url": "https://www.ncbi.nlm.nih.gov/gene/417852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417852", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417852", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WQVYWEV", "url": "https://omabrowser.org/oma/group/WQVYWEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB62", "url": "https://www.orthodb.org/?gene=A0A8V0YB62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10258:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10258:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03185", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03185", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296052", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296052", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186559", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGRAAYEYTEAEDKSMRLGFLLIAAGLLSLLGLGCFWLRPALQERGGGGAANCTVLAVRQLGERFACTFSCGAACRGTARYPCLQVLVRTSRSAAPALLHEDERQLRTNPKCSYIPPCARDDQENSENVTYKQKYWKEKVGSQPFTCYFNQHLRPDDVMLKRTHDETILLHCFLWPLVTFLLGVLIVALTACARSLAAKAEAIQRKKHS", "length": 211, "header": "tr|A0A8V0YB62-1|A0A8V0YB62_CHICK Isoform 1 of Potassium calcium-activated channel subfamily M regulatory beta subunit 4 OS=Gallus gallus OX=9031 GN=KCNMB4 PE=4 SV=1 CANONICAL=A0A8V0YB62-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62/entry#A0A8V0YB62-1", "sequence": { "sequence": "MARGRAAYEYTEAEDKSMRLGFLLIAAGLLSLLGLGCFWLRPALQERGGGGAANCTVLAVRQLGERFACTFSCGAACRGTARYPCLQVLVRTSRSAAPALLHEDERQLRTNPKCSYIPPCARDDQENSENVTYKQKYWKEKVGSQPFTCYFNQHLRPDDVMLKRTHDETILLHCFLWPLVTFLLGVLIVALTACARSLAAKAEAIQRKKHS", "length": 211, "header": "tr|A0A8V0YB62-1|A0A8V0YB62_CHICK Isoform 1 of Potassium calcium-activated channel subfamily M regulatory beta subunit 4 OS=Gallus gallus OX=9031 GN=KCNMB4 PE=4 SV=1 CANONICAL=A0A8V0YB62-1" }, "locus": { "chromosome": "1", "start_pos": 35955476, "end_pos": 35944975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028287.1", "url": "https://www.ensembl.org/id/ENSGALT00010028287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016202.1", "url": "https://www.ensembl.org/id/ENSGALP00010016202.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "\u03b24-subunit increases Slo responsiveness to physiological Ca2+ concentrations and together with \u03b21 reduces surface expression of Slo in hair cells.", "journal": "American journal of physiology. Cell physiology", "date": "2011-03", "authors": "Bai Jun-Ping, Surguchev Alexei, Navaratnam Dhasakumar", "evidence": [ { "database": "RefSeq", "id": "NP_001186559", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186559" } ], "reference": [ { "type": "PubMed", "id": "21178105", "url": "https://glygen.org/publication/PubMed/21178105" } ] } ], "pathway": [ { "id": "gga:417852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417852", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296052", "resource": "Reactome", "description": "Ca2+ activated K+ channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuronal action potential", "id": "GO:0019228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62" } ], "pmid": "" }, { "name": "detection of calcium ion", "id": "GO:0005513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62" } ], "pmid": "" }, { "name": "calcium-activated potassium channel activity", "id": "GO:0015269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0YB64-1", "uniprot_ac": "A0A8V0YB64", "uniprot_id": "A0A8V0YB64_CHICK", "mass": { "chemical_mass": 72259.0, "monoisotopic_mass": 72259.0 }, "refseq": { "ac": "XP_046790617", "name": "Fanconi anemia group G protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046790617" }, "gene_names": [ { "name": "FANCG", "type": "recommended", "evidence": [ { "id": "A0A8V0YB64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB64" } ] }, { "name": "FANCG", "type": "synonym", "evidence": [ { "id": "XP_046790617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046790617" } ] } ], "protein_names": [ { "name": "Fanconi anemia complementation group G", "type": "synonym", "evidence": [ { "id": "A0A8V0YB64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB64/entry#names_and_taxonomy" } ] }, { "name": "Fanconi anemia group G protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046790617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046790617" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046790617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046790617" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FANCG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB64", "locus": { "chromosome": "Z", "start_pos": 9108885, "end_pos": 9120055, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011464", "url": "https://www.ensembl.org/id/ENSGALG00010011464" } ] } } ], "crossref": [ { "id": "A0A8V0YB64", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YB64", "database": "AlphaFoldDB", "categories": [] }, { "id": "378893", "url": "https://www.ncbi.nlm.nih.gov/gene/378893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB64", "url": "https://www.orthodb.org/?gene=A0A8V0YB64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15254:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15254:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046790617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046790617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRLRCGTAPEPGCLQAWAAECEALAGRWRAARGSAYGGAAAAARQLRGAFGELLLQMRGLPPALPMMPLELTVLYNSLLFVMGTSDCAIKGEAEGIRQGLLRVLEACGTSGQDLSTQELWQKVLQEVTVEELQAPLHRLGALQAAWWLATSCLQNIIDLFRLLSSAEDPERAPCRAEKNELLTLLKAWRTPAEEASVSLVQSTEDLKETLCTAAAFLQGLQELEAGNLSTTLCLLQEAAGGFCSKRVLAQIYVCLGCCAQRMGKPQTALQHLKQALQVDFQCHPALSHTAAVYHELGETDAELQALYLLYEVCLLWKKNPPSATSSSPYFLIRAELLVNTPILASLLRHHHPSEVKYLLAQRCLRDGRVADAVEHYLDFLSLLQEGLQQQVPLDGGSPLPRIPEVFLEAASALEQDGRHQDSLTVCDEVISRTTNLIPKIIQVEEKLEQPECASLETGLAGGLLSQKRESLCCLTWRAAAYLHQGWVWSKLGKGKEAIMQFSRCLNDLLRFQPRGCGVEPAESLLPEVKVLQKIRLLSLIGRGMQFLEQEKHKEALLDFQHGLQISPDDPAAASYLVQVLWKLNRKEEAADYWQKYLESPAGEDGQQERQGRHFPLYLDSCLKQATFPQNESLARCIQDYLRTTRQDSSR", "length": 651, "header": "tr|A0A8V0YB64-1|A0A8V0YB64_CHICK Isoform 1 of Fanconi anemia complementation group G OS=Gallus gallus OX=9031 GN=FANCG PE=4 SV=1 CANONICAL=A0A8V0YB64-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB64/entry#A0A8V0YB64-1", "sequence": { "sequence": "MKRLRCGTAPEPGCLQAWAAECEALAGRWRAARGSAYGGAAAAARQLRGAFGELLLQMRGLPPALPMMPLELTVLYNSLLFVMGTSDCAIKGEAEGIRQGLLRVLEACGTSGQDLSTQELWQKVLQEVTVEELQAPLHRLGALQAAWWLATSCLQNIIDLFRLLSSAEDPERAPCRAEKNELLTLLKAWRTPAEEASVSLVQSTEDLKETLCTAAAFLQGLQELEAGNLSTTLCLLQEAAGGFCSKRVLAQIYVCLGCCAQRMGKPQTALQHLKQALQVDFQCHPALSHTAAVYHELGETDAELQALYLLYEVCLLWKKNPPSATSSSPYFLIRAELLVNTPILASLLRHHHPSEVKYLLAQRCLRDGRVADAVEHYLDFLSLLQEGLQQQVPLDGGSPLPRIPEVFLEAASALEQDGRHQDSLTVCDEVISRTTNLIPKIIQVEEKLEQPECASLETGLAGGLLSQKRESLCCLTWRAAAYLHQGWVWSKLGKGKEAIMQFSRCLNDLLRFQPRGCGVEPAESLLPEVKVLQKIRLLSLIGRGMQFLEQEKHKEALLDFQHGLQISPDDPAAASYLVQVLWKLNRKEEAADYWQKYLESPAGEDGQQERQGRHFPLYLDSCLKQATFPQNESLARCIQDYLRTTRQDSSR", "length": 651, "header": "tr|A0A8V0YB64-1|A0A8V0YB64_CHICK Isoform 1 of Fanconi anemia complementation group G OS=Gallus gallus OX=9031 GN=FANCG PE=4 SV=1 CANONICAL=A0A8V0YB64-1" }, "locus": { 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGAAAAAVGCLTRLSPAALAVKFGVRQRSPHCLLVKEHRVREGPGDTHPPQRTLFVLNVPPYCSAVSGDALSRLFARCGAVQSVDLRDKPGPGEKAEKRTSKFFTNGTATGFRVAYVVFRKPAGVQAAKALSQEGPLLISTESHPVKTGISKWIARYADSVVDREELKAEVDAYMQDYDKKIEEEEAKAAKEEGVPDEEGWVKVTRKGRKPGLPRTEAANLRVLEREKRKKARKELLNFYAWQHRETKREHIAQLRKKFEEDKQRIALMRAQRKFRPY", "length": 279, "header": "tr|A0A8V0YB77-1|A0A8V0YB77_CHICK Isoform 1 of Ribosomal RNA processing 7 homolog A OS=Gallus gallus OX=9031 GN=RRP7A PE=1 SV=1 CANONICAL=A0A8V0YB77-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77/entry#A0A8V0YB77-1", "sequence": { "sequence": "MRGAAAAAVGCLTRLSPAALAVKFGVRQRSPHCLLVKEHRVREGPGDTHPPQRTLFVLNVPPYCSAVSGDALSRLFARCGAVQSVDLRDKPGPGEKAEKRTSKFFTNGTATGFRVAYVVFRKPAGVQAAKALSQEGPLLISTESHPVKTGISKWIARYADSVVDREELKAEVDAYMQDYDKKIEEEEAKAAKEEGVPDEEGWVKVTRKGRKPGLPRTEAANLRVLEREKRKKARKELLNFYAWQHRETKREHIAQLRKKFEEDKQRIALMRAQRKFRPY", "length": 279, "header": "tr|A0A8V0YB77-1|A0A8V0YB77_CHICK Isoform 1 of Ribosomal RNA processing 7 homolog A OS=Gallus gallus OX=9031 GN=RRP7A PE=1 SV=1 CANONICAL=A0A8V0YB77-1" }, "locus": { "chromosome": "1", "start_pos": 49242651, "end_pos": 49239559, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026267.1", "url": "https://www.ensembl.org/id/ENSGALT00010026267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014890.1", "url": "https://www.ensembl.org/id/ENSGALP00010014890.1" } ] } }, { "isoform_ac": "A0A8V0YFV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77/entry#A0A8V0YFV6-1", "sequence": { "sequence": "MAAAEPRVAVTAPPGYTALAVKFGVRQRSPHCLLVKEHRVREGPGDTHPPQRTLFVLNVPPYCSAVSGDALSRLFARCGAVQSVDLRDKPGPGEKAEKRTSKFFTNGTATGFRVAYVVFRKPAGVQAAKALSQEGPLLISTESHPVKTGISKWIARYADSVVDREELKAEVDAYMQDYDKKIEEEEAKAAKEEGVPDEEGWVKVTRKGRKPGLPRTEAANLRVLEREKRKKARKELLNFYAWQHRETKREHIAQLRKKFEEDKQRIALMRAQRKFRPY", "length": 278, "header": "tr|A0A8V0YFV6-1|A0A8V0YB77_CHICK Computationally mapped isoform of Ribosomal RNA processing 7 homolog A OS=Gallus gallus OX=9031 GN=RRP7A PE=1 SV=1 CANONICAL=A0A8V0YB77-1" }, "locus": { "chromosome": "1", "start_pos": 49242651, "end_pos": 49239483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026264.1", "url": "https://www.ensembl.org/id/ENSGALT00010026264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014888.1", "url": "https://www.ensembl.org/id/ENSGALP00010014888.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": 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norvegicus", "sequence": { "sequence": "MVSRRKKQKAGGHEGSVPSPPGYSAVPVKFSEKQQASHYLYMRQHRVRQGTQSTWPANRTLFILNVPPYCTQESLSRCLSSCGTIKTVELQEKPDLAESPKEPKSQFFHPKPVPGFQVAYVVFQKPGGVSAALNLKGPLLVSTESHPVKNGIHKWISDYEDSVLDPEALRLEVDTFMEAYDKKIAEEETKAKEEEGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLEKERRKRARKELLSFYAWQHRETKMEHLAQLRKKFEEDKQRIELMRAQRKFRPY", "length": 280 }, "evidence": [ { "id": "A0A8V0YB77", "url": "https://omabrowser.org/oma/group/A0A8V0YB77/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D1C9-1", "protein_name": "Ribosomal RNA-processing protein 7 homolog A", "gene_name": "Rrp7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSRRKKRKAGGHEESIPSPPGYSAVPVKFSAKQQAPHYLYMRQHRVRQGTQSTWPPDRTLFILNVPPYCTQESLSRCLSCCGTIKTVELQEKPDLAESPTEPKSQFFHPKPVPGFQVAYVVFQKPSGVSAALNLKGPLLVSTESHLVKSGIHKWISDYEDSVLDPEALRMEVDAFMEAYDKKIAEEEAKAKEEEGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLEKEKRKRARKELLNFYAWQHRETKMEHLAQLRKKFEEDKQRIELMRAQRKFRPY", "length": 280 }, "evidence": [ { "id": "A0A8V0YB77", "url": "https://omabrowser.org/oma/group/A0A8V0YB77/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VMJ1-1", "protein_name": "Ribosomal RNA-processing protein 7 homolog A", "gene_name": "Rrp7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVELEGYVVVPLRTTPKAQHCHSIYMREHFIRLMDPNKPKGRTLFLLNVPPYVTEDSLRTVFGRAGSIEAVEFAAKPGKEETIKWYEGTGEPFSNTRPPFVFKVAYIVFEKNSSIGKALALKSIDLFNSSGECIVKTGMELWHEEYDCNYLLDAQKTKLQISKYMAGYDKRERAAAQAAKTGEADADGWVTVGKEGRNAGFEQKASVIGRLEEKVAKGNKTKELKNFYTFQIRESKMQNIVEMRKKFEEEKRKIGLLKQSRRFKPF", "length": 266 }, "evidence": [ { "id": "A0A8V0YB77", "url": "https://omabrowser.org/oma/group/A0A8V0YB77/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3A4-1", "protein_name": "Ribosomal RNA-processing protein 7 homolog A", "gene_name": "RRP7A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVARRRKCAARDPEDRIPSPLGYAAIPIKFSEKQQASHYLYVRAHGVRQGTKSTWPQKRTLFVLNVPPYCTEESLSRLLSTCGLVQSVELQEKPDLAESPKESRSKFFHPKPVPGFQVAYVVFQKPSGVSAALALKGPLLVSTESHPVKSGIHKWISDYADSVPDPEALRVEVDTFMEAYDQKIAEEEAKAKEEEGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLERERRKRSRKELLNFYAWQHRESKMEHLAQLRKKFEEDKQRIELLRAQRKFRPY", "length": 280 }, "evidence": [ { "id": "A0A8V0YB77", "url": "https://omabrowser.org/oma/group/A0A8V0YB77/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein localization to nucleolus", "id": "GO:1902570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902570", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77" } ], "pmid": "" }, { "name": "cilium disassembly", "id": "GO:0061523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB77" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YB81-1", "uniprot_ac": "A0A8V0YB81", "uniprot_id": "A0A8V0YB81_CHICK", "mass": { "chemical_mass": 63818.0, "monoisotopic_mass": 63818.0 }, "refseq": {}, "gene_names": [ { "name": "LCORL", "type": "recommended", "evidence": [ { "id": "A0A8V0YB81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB81" } ] } ], "protein_names": [ { "name": "Ligand dependent nuclear receptor 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"AlphaFoldDB", "categories": [] }, { "id": "422820", "url": "https://www.ncbi.nlm.nih.gov/gene/422820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB81", "url": "https://www.orthodb.org/?gene=A0A8V0YB81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB86", "url": "https://www.orthodb.org/?gene=A0A8V0YB86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFW7", "url": "https://www.orthodb.org/?gene=A0A8V0YFW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21545", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21545", "database": 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"url": "https://omabrowser.org/oma/group/STAEQCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBB2", "url": "https://www.orthodb.org/?gene=A0A8V0YBB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDJ3", "url": "https://www.orthodb.org/?gene=A0A8V0YDJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDJ6", "url": "https://www.orthodb.org/?gene=A0A8V0YDJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI76", "url": "https://www.orthodb.org/?gene=A0A8V0YI76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI86", "url": "https://www.orthodb.org/?gene=A0A8V0YI86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22774:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22774:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24917", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24917", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040513387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040513387", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSKLPWQDEGVDKYSPFFCLQFTKNLSPDKINLSTLKGEGQLTNLELDQEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVVMEMSTCEEPRAPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNANWEHADLRFTRIQEAQRGEVLTFKEINWQMIRIEADAIQSSKHEIMSAPVRLITNQSKIRVTLKRRLKDCNVVASKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSLASETTQSSAPAPSSQQVKAHQTAAAPDQNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHSKEKDSNRRVTGGAMQLSFSYLTVDYYPFHKAGDSCNHWMHYSDATKARSGWAQELLNEFKSNVELLKQAVKDQGIGSPDTSPPAVSPQKPQTGKEQALKGTSQQPKGKLMSSPVVVRLADFNIYQVSTADQCRSSPKSLVSCNKKSLYLPPEMPAIHFEFTEYYYPDGKDFPIPCPNLYGQLNALQFTLDERSILWLNQFVLDLKQSLIQFMAMYKLNDNSKSDEHVDVRVDGLMLKFIIPAENKLEIHKDQPRALSIQSSEMIATNTRYSPNCRHSDLEALFQNFKDCEFFSRTFTTFPKSQKNFNLLHPIFQRHAHEQDTKMHDVYKGYIIPKLNKYALKTSAATDVWALHFSQFWIDYEGTKSGKGRPVSFVDSFPLSLWICQPLRFAKSQKELLSHNQPAFNIPKSESSDLANRLQRKKLLKEYYSSETEPLANGIQMTHFSDTSGVLSESSSSDADVHVLVHVQKHVSMQINHYQYLFLLFLHESLVLLLENLRNDVEAVTGKPAKQTDICIGFLLKSAELALLLHPVSQGNPCKSPVVEGGSPMASELSPLGNGEAHTSENKSANNKMEQSGINNIDYVSDCKPVNAEVKGVLMDPLLFKSDSTMDFQKGTSFSDDASDKGLGDTSEGGSSGLFSRSDSEEVYGPLSDRSGLYHRDSLSILSKREDSTEFFIDKEDDRNMFSNKLNELEGTTEACLNQVTDLETETTLESEELEINKEKVTSVRMFASQSSSSAKPKDRCPSSLPAFSVSYKNMKRSPSQVSLDTISIDSMMLEEHLVESDGSDSQSFLEKGITATNYQSPSENAHEGGTVIENCDGSSPDAMSAASENAHETSEEMMSVVVFQIFGVNGEIDIRGEDTEICLQVNQVIPNQLGNISVRHYLCNRTVGSDCKAVAGPVKPSPEISLRWESGPSAIIHSLLAVKNGFLQCHVENFSAEFLTSSLTNIQHFLEDEAVAEVMPMKIKVSNAIINLKDDSPRENLKACELVPIKLHIDILWIERNDDGSFFIRDNQRVNDGSKMKNSSSALQQATRPAGHKTQDQATQTTCEIPSPVKSNRDSADFIKNELIEENECLKQELAKAKAALAEVQMEKDALLHRIKKMNVDYQ", "length": 1458, "header": "tr|A0A8V0YBB2-1|A0A8V0YBB2_CHICK Isoform 1 of Bridge-like lipid transfer protein family member 3B OS=Gallus gallus OX=9031 GN=UHRF1BP1L PE=4 SV=1 CANONICAL=A0A8V0YBB2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2/entry#A0A8V0YBB2-1", "sequence": { "sequence": "MSRSKLPWQDEGVDKYSPFFCLQFTKNLSPDKINLSTLKGEGQLTNLELDQEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVVMEMSTCEEPRAPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNANWEHADLRFTRIQEAQRGEVLTFKEINWQMIRIEADAIQSSKHEIMSAPVRLITNQSKIRVTLKRRLKDCNVVASKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSLASETTQSSAPAPSSQQVKAHQTAAAPDQNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHSKEKDSNRRVTGGAMQLSFSYLTVDYYPFHKAGDSCNHWMHYSDATKARSGWAQELLNEFKSNVELLKQAVKDQGIGSPDTSPPAVSPQKPQTGKEQALKGTSQQPKGKLMSSPVVVRLADFNIYQVSTADQCRSSPKSLVSCNKKSLYLPPEMPAIHFEFTEYYYPDGKDFPIPCPNLYGQLNALQFTLDERSILWLNQFVLDLKQSLIQFMAMYKLNDNSKSDEHVDVRVDGLMLKFIIPAENKLEIHKDQPRALSIQSSEMIATNTRYSPNCRHSDLEALFQNFKDCEFFSRTFTTFPKSQKNFNLLHPIFQRHAHEQDTKMHDVYKGYIIPKLNKYALKTSAATDVWALHFSQFWIDYEGTKSGKGRPVSFVDSFPLSLWICQPLRFAKSQKELLSHNQPAFNIPKSESSDLANRLQRKKLLKEYYSSETEPLANGIQMTHFSDTSGVLSESSSSDADVHVLVHVQKHVSMQINHYQYLFLLFLHESLVLLLENLRNDVEAVTGKPAKQTDICIGFLLKSAELALLLHPVSQGNPCKSPVVEGGSPMASELSPLGNGEAHTSENKSANNKMEQSGINNIDYVSDCKPVNAEVKGVLMDPLLFKSDSTMDFQKGTSFSDDASDKGLGDTSEGGSSGLFSRSDSEEVYGPLSDRSGLYHRDSLSILSKREDSTEFFIDKEDDRNMFSNKLNELEGTTEACLNQVTDLETETTLESEELEINKEKVTSVRMFASQSSSSAKPKDRCPSSLPAFSVSYKNMKRSPSQVSLDTISIDSMMLEEHLVESDGSDSQSFLEKGITATNYQSPSENAHEGGTVIENCDGSSPDAMSAASENAHETSEEMMSVVVFQIFGVNGEIDIRGEDTEICLQVNQVIPNQLGNISVRHYLCNRTVGSDCKAVAGPVKPSPEISLRWESGPSAIIHSLLAVKNGFLQCHVENFSAEFLTSSLTNIQHFLEDEAVAEVMPMKIKVSNAIINLKDDSPRENLKACELVPIKLHIDILWIERNDDGSFFIRDNQRVNDGSKMKNSSSALQQATRPAGHKTQDQATQTTCEIPSPVKSNRDSADFIKNELIEENECLKQELAKAKAALAEVQMEKDALLHRIKKMNVDYQ", "length": 1458, "header": "tr|A0A8V0YBB2-1|A0A8V0YBB2_CHICK Isoform 1 of Bridge-like lipid transfer protein family member 3B OS=Gallus gallus OX=9031 GN=UHRF1BP1L PE=4 SV=1 CANONICAL=A0A8V0YBB2-1" }, "locus": { "chromosome": "1", "start_pos": 47268335, "end_pos": 47231578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027496.1", "url": "https://www.ensembl.org/id/ENSGALT00010027496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015742.1", "url": "https://www.ensembl.org/id/ENSGALP00010015742.1" } ] } }, { "isoform_ac": "A0A8V0YDJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2/entry#A0A8V0YDJ3-1", "sequence": { "sequence": "MQTGNTLTSDLPGYKKLNVERVLTFKEINWQMIRIEADAIQSSKHEIMSAPVRLITNQSKIRVTLKRRLKDCNVVASKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSLASETTQSSAPAPSSQQVKAHQTAAAPDQNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHSKEKDSNRRVTGGAMQLSFSYLTVDYYPFHKAGDSCNHWMHYSDATKARSGWAQELLNEFKSNVELLKQAVKDQGIGSPDTSPPAVSPQKPQTGKEQALKGTSQQPKGKLMSSPVVVRLADFNIYQVSTADQCRSSPKSLVSCNKKSLYLPPEMPAIHFEFTEYYYPDGKDFPIPCPNLYGQLNALQFTLDERSILWLNQFVLDLKQSLIQFMAMYKLNDNSKSDEHVDVRVDGLMLKFIIPAENKLEIHKDQPRALSIQSSEMIATNTRYSPNCRHSDLEALFQNFKDCEFFSRTFTTFPKSQKNFNLLHPIFQRHAHEQDTKMHDVYKGYIIPKLNKYALKTSAATDVWALHFSQFWIDYEGTKSGKGRPVSFVDSFPLSLWICQPLRFAKSQKELLSHNQPAFNIPKSESSDLANRLQRKKLLKEYYSSETEPLANGIQMTHFSDTSGVLSESSSSDADVHVLVHVQKHVSMQINHYQYLFLLFLHESLVLLLENLRNDVEAVTGKPAKQTDICIGFLLKSAELALLLHPVSQGNPCKSPVVEGGSPMASELSPLGNGEAHTSENKSANNKMEQSGINNIDYVSDCKPVNAEVKGVLMDPLLFKSDSTMDFQKGTSFSDDASDKGLGDTSEGGSSGLFSRSDSEEVYGPLSDRSGLYHRDSLSILSKREDSTEFFIDKEDDRNMFSNKLNELEGTTEACLNQVTDLETETTLESEELEINKEKVTSVRMFASQSSSSAKPKDRCPSSLPAFSVSYKNMKRSPSQVSLDTISIDSMMLEEHLVESDGSDSQSFLEKGITATNYQSPSENAHEGGTVIENCDGSSPDAMSAASENAHETSEEMMSVVVFQIFGVNGEIDIRGEDTEICLQVNQVIPNQLGNISVRHYLCNRTVGSDCKAVAGPVKPSPEISLRWESGPSAIIHSLLAVKNGFLQCHVENFSAEFLTSSLTNIQHFLEDEAVAEVMPMKIKVSNAIINLKDDSPRENLKACELVPIKLHIDILWIERNDDGSFFIRDNQRVNDGSKMKNSSSALQQATRPAGHKTQDQATQTTCEIPSPVKSNRDSADFIKNELIEENECLKQELAKAKAALAEVQMEKDALLHRIKKMNVDYQ", "length": 1295, "header": "tr|A0A8V0YDJ3-1|A0A8V0YBB2_CHICK Computationally mapped isoform of Bridge-like lipid transfer protein family member 3B OS=Gallus gallus OX=9031 GN=UHRF1BP1L PE=4 SV=1 CANONICAL=A0A8V0YBB2-1" }, "locus": { "chromosome": "1", "start_pos": 47262068, "end_pos": 47231578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027492.1", "url": "https://www.ensembl.org/id/ENSGALT00010027492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015738.1", "url": "https://www.ensembl.org/id/ENSGALP00010015738.1" } ] } }, { "isoform_ac": "A0A8V0YDJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2/entry#A0A8V0YDJ6-1", "sequence": { "sequence": "MRCIVQIILLLLVKRTEERFTKNLSPDKINLSTLKGEGQLTNLELDQEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVVMEMSTCEEPRAPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNANWEHADLRFTRIQEAQRGEVLTFKEINWQMIRIEADAIQSSKHEIMSAPVRLITNQSKIRVTLKRRLKDCNVVASKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSLASETTQSSAPAPSSQQVKAHQTAAAPDQNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHSKEKDSNRRVTGGAMQLSFSYLTVDYYPFHKAGDSCNHWMHYSDATKARSGWAQELLNEFKSNVELLKQAVKDQGIGSPDTSPPAVSPQKPQTGKEQALKGTSQQPKGKLMSSPVVVRLADFNIYQVSTADQCRSSPKSLVSCNKKSLYLPPEMPAIHFEFTEYYYPDGKDFPIPCPNLYGQLNALQFTLDERSILWLNQFVLDLKQSLIQFMAMYKLNDNSKSDEHVDVRVDGLMLKFIIPAENKLEIHKDQPRALSIQSSEMIATNTRYSPNCRHSDLEALFQNFKDCEFFSRTFTTFPKSQKNFNLLHPIFQRHAHEQDTKMHDVYKGYIIPKLNKYALKTSAATDVWALHFSQFWIDYEGTKSGKGRPVSFVDSFPLSLWICQPLRFAKSQKELLSHNQPAFNIPKSESSDLANRLQRKKLLKEYYSSETEPLANGIQMTHFSDTSGVLSESSSSDADVHVLVHVQKHVSMQINHYQYLFLLFLHESLVLLLENLRNDVEAVTGKPAKQTDICIGFLLKSAELALLLHPVSQGNPCKSPVVEGGSPMASELSPLGNGEAHTSENKSANNKMEQSGINNIDYVSDCKPVNAEVKGVLMDPLLFKSDSTMDFQKGTSFSDDASDKGLGDTSEGGSSGLFSRSDSEEVYGPLSDRSGLYHRDSLSILSKREDSTEFFIDKEDDRNMFSNKLNELEGTTEACLNQVTDLETETTLESEELEINKEKVTSVRMFASQSSSSAKPKDRCPSSLPAFSVSYKNMKRSPSQVSLDTISIDSMMLEEHLVESDGSDSQSFLEKGITATNYQSPSENAHEGGTVIENCDGSSPDAMSAASENAHETSEEMMSVVVFQIFGVNGEIDIRGEDTEICLQVNQVIPNQLGNISVRHYLCNRTVGSDCKAVAGPVKPSPEISLRWESGPSAIIHSLLAVKNGFLQCHVENFSAEFLTSSLTNIQHFLEDEAVAEVMPMKIKVSNAIINLKDDSPRENLKACELVPIKLHIDILWIERNDDGSFFIRDNQRVNDGSKMKNSSSALQQATRPAGHKTQDQATQTTCEIPSPVKSNRDSADFIKNELIEENECLKQELAKAKAALAEVQMEKDALLHRIKKMNVDYQ", "length": 1454, "header": "tr|A0A8V0YDJ6-1|A0A8V0YBB2_CHICK Computationally mapped isoform of Bridge-like lipid transfer protein family member 3B OS=Gallus gallus OX=9031 GN=UHRF1BP1L PE=4 SV=1 CANONICAL=A0A8V0YBB2-1" }, "locus": { "chromosome": "1", "start_pos": 47269223, "end_pos": 47231578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027498.1", "url": "https://www.ensembl.org/id/ENSGALT00010027498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015744.1", "url": "https://www.ensembl.org/id/ENSGALP00010015744.1" } ] } }, { "isoform_ac": "A0A8V0YI76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2/entry#A0A8V0YI76-1", "sequence": { "sequence": "MHYSDATKARSGWAQELLNEFKSNVELLKQAVKDQGIGSPDTSPPAVSPQKPQTGKEQALKGTSQQPKGKLMSSPVVVRLADFNIYQVSTADQCRSSPKSLVSCNKKSLYLPPEMPAIHFEFTEYYYPDGKDFPIPCPNLYGQLNALQFTLDERSILWLNQFVLDLKQSLIQFMAMYKLNDNSKSDEHVDVRVDGLMLKFIIPAENKLEIHKDQPRALSIQSSEMIATNTRYSPNCRHSDLEALFQNFKDCEFFSRTFTTFPKSQKNFNLLHPIFQRHAHEQDTKMHDVYKGYIIPKLNKYALKTSAATDVWALHFSQFWIDYEGTKSGKGRPVSFVDSFPLSLWICQPLRFAKSQKELLSHNQPAFNIPKSESSDLANRLQRKKLLKEYYSSETEPLANGIQMTHFSDTSGVLSESSSSDADVHVLVHVQKHVSMQINHYQYLFLLFLHESLVLLLENLRNDVEAVTGKPAKQTDICIGFLLKSAELALLLHPVSQGNPCKSPVVEGGSPMASELSPLGNGEAHTSENKSANNKMEQSGINNIDYVSDCKPVNAEVKGVLMDPLLFKSDSTMDFQKGTSFSDDASDKGLGDTSEGGSSGLFSRSDSEEVYGPLSDRSGLYHRDSLSILSKREDSTEFFIDKEDDRNMFSNKLNELEGTTEACLNQVTDLETETTLESEELEINKEKVTSVRMFASQSSSSAKPKDRCPSSLPAFSVSYKNMKRSPSQVSLDTISIDSMMLEEHLVESDGSDSQSFLEKGITATNYQSPSENAHEGGTVIENCDGSSPDAMSAASENAHETSEEMMSVVVFQIFGVNGEIDIRGEDTEICLQVNQVIPNQLGNISVRHYLCNRTVGSDCKAVAGPVKPSPEISLRWESGPSAIIHSLLAVKNGFLQCHVENFSAEFLTSSLTNIQHFLEDEAVAEVMPMKIKVSNAIINLKDDSPRENLKACELVPIKLHIDILWIERNDDGSFFIRDNQRVNDGSKMKNSSSALQQATRPAGHKTQDQATQTTCEIPSPVKSNRDSADFIKNEHNCQRQRTGWLSQVVTNLSVISGF", "length": 1058, "header": "tr|A0A8V0YI76-1|A0A8V0YBB2_CHICK Computationally mapped isoform of Bridge-like lipid transfer protein family member 3B OS=Gallus gallus OX=9031 GN=UHRF1BP1L PE=4 SV=1 CANONICAL=A0A8V0YBB2-1" }, "locus": { "chromosome": "1", "start_pos": 47251632, "end_pos": 47232019, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027490.1", "url": "https://www.ensembl.org/id/ENSGALT00010027490.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015736.1", "url": "https://www.ensembl.org/id/ENSGALP00010015736.1" } ] } }, { "isoform_ac": "A0A8V0YI86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2/entry#A0A8V0YI86-1", "sequence": { "sequence": "MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGQLTNLELDQEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVVMEMSTCEEPRAPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNANWEHADLRFTRIQEAQRGEVLTFKEINWQMIRIEADAIQSSKHEIMSAPVRLITNQSKIRVTLKRRLKDCNVVASKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSLASETTQSSAPAPSSQQVKAHQTAAAPDQNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHSKEKDSNRRVTGGAMQLSFSYLTVDYYPFHKAGDSCNHWMHYSDATKARSGWAQELLNEFKSNVELLKQAVKDQGIGSPDTSPPAVSPQKPQTGKEQALKGTSQQPKGKLMSSPVVVRLADFNIYQVSTADQCRSSPKSLVSCNKKSLYLPPEMPAIHFEFTEYYYPDGKDFPIPCPNLYGQLNALQFTLDERSILWLNQFVLDLKQSLIQFMAMYKLNDNSKSDEHVDVRVDGLMLKFIIPAENKLEIHKDQPRALSIQSSEMIATNTRYSPNCRHSDLEALFQNFKDCEFFSRTFTTFPKSQKNFNLLHPIFQRHAHEQDTKMHDVYKGYIIPKLNKYALKTSAATDVWALHFSQFWIDYEGTKSGKGRPVSFVDSFPLSLWICQPLRFAKSQKELLSHNQPAFNIPKSESSDLANRLQRKKLLKEYYSSETEPLANGIQMTHFSDTSGVLSESSSSDADVHVLVHVQKHVSMQINHYQYLFLLFLHESLVLLLENLRNDVEAVTGKPAKQTDICIGFLLKSAELALLLHPVSQGNPCKSPVVEGGSPMASELSPLGNGEAHTSENKSANNKMEQSGINNIDYVSDCKPVNAEVKGVLMDPLLFKSDSTMDFQKGTSFSDDASDKGLGDTSEGGSSGLFSRSDSEEVYGPLSDRSGLYHRDSLSILSKREDSTEFFIDKEDDRNMFSNKLNELEGTTEACLNQVTDLETETTLESEELEINKEKVTSVRMFASQSSSSAKPKDRCPSSLPAFSVSYKNMKRSPSQVSLDTISIDSMMLEEHLVESDGSDSQSFLEKGITATNYQSPSENAHEGGTVIENCDGSSPDAMSAASENAHETSEEMMSVVVFQIFGVNGEIDIRGEDTEICLQVNQVIPNQLGNISVRHYLCNRTVGSDCKAVAGPVKPSPEISLRWESGPSAIIHSLLAVKNGFLQCHVENFSAEFLTSSLTNIQHFLEDEAVAEVMPMKIKVSNAIINLKDDSPRENLKACELVPIKLHIDILWIERNDDGSFFIRDNQRVNDGSKMKNSSSALQQATRPAGHKTQDQATQTTCEIPSPVKSNRDSADFIKNELIEENECLKQELAKAKAALAEVQMEKDALLHRIKKMNVDYQ", "length": 1450, "header": "tr|A0A8V0YI86-1|A0A8V0YBB2_CHICK Computationally mapped isoform of Bridge-like lipid transfer protein family member 3B OS=Gallus gallus OX=9031 GN=UHRF1BP1L PE=4 SV=1 CANONICAL=A0A8V0YBB2-1" }, "locus": { "chromosome": "1", "start_pos": 47284187, "end_pos": 47231578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027501.1", "url": "https://www.ensembl.org/id/ENSGALT00010027501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015747.1", "url": "https://www.ensembl.org/id/ENSGALP00010015747.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y0N1-1", "protein_name": "Bridge-like lipid transfer protein family member 3B", "gene_name": "Bltp3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "KKCLLEKEIIALIIVQFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRVRFGGLRRLPSLDKVVMEMSTCEEPRAPNGPSPIATASGQSEYGFAEKVVEGITVSVNSIVIRIGAKAFNASFELSQLRIYSVNAQWEHGDLRFTRIQDPQRGEVLTFKEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSMAPEPAQSSTITSSAQHVKTPQAANAPDLGDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHAKEKESSRRISGGAMQLSFTQLTVDYYPYHKAGDSCSHWMYFSDATKTKIGWANELLHEFECNVEMLTQAMKDHNLGSPPKSPTHASPQHTQTEKDSTLKGTPRTPSVSSQPSKAKLMSSSVVVRLADFNIYQVSTAEQCRSSPKSMISCNKKSLYLPQEMSAIYIEFTEYYYPDGKDFPIPSPNLYSQLNALQFTVDERSILWLNQFILDLKQSLNQFMAVYKLNDSSKSDEHVDIRVDGLMLKFVIPSEVKPGCHRDQPHTVSIQSSEMIATNTRHCPNCRHSDLEALFQDFKDIDFFSKTYTRFPKSCDSFNLLHPIFQRHAHEQDTKMHEVYKGNIIPKLNKNTLKPSAATDVWAVHFSQFWIDYEGMKSGKGRPVSFVDAFPLSVWICQPTRYAELQKEFQTCDQVTLNTSQSESSDLAGRMKRKKLLKEYYSTESESLTNGGQRPPSDAFLRFSSPSSDADVHVLVRVHKHVSMQINHYQYLLLLFIHESLVLLSDTLRKDVEAVTGSPATQTSVCVGVLLRSAELALLLHPVNHTSALRSPASESGSPLLPDYLPAENGGILSSKRKQGGSGVHRIRNATLSHMSDNRSMSVDLSHAPLKDPLLFKSASDTNLQKGTSFLDYLSDKHLGKISEDESSGLVYKSGAGEMASEVSHTKGVACTDSDSVSDYREDSATISLDNDANQITRSNAAARKGNETIRSIFKAEDFPPETASLSESLENSKEEAPTARALKSQPPLSVKSKEHCPPTPAPLSVSYKNMKRSASQISLDTVSLDSVGFEEQLESDGSDSHVLLGRAIKRNSSTSCQSPAESGNINANMQNCGEASPDAVSTTSEGTQELRDDLMSVVVFKIIGVSGEIDIRGEDTEVCLQVNQVTPSQLGNVSLRHYLSNRPIGSDQKAIIHPKSSPEISLRFESGPGAVVHSLLAEKNGFLQCHIENFTTEFLTSSLVNLQHFLEDDTVATAMPMKIQVSNTQINVTDDSPRGSTVSLQPSPVTVHIDHLVVERNDDGSFHIRDSQLFNTGTDFKDSASSNSEVRTRGTCDVRKQSSVTQATQTSPEVPLPSQSATFPEGSVDITREQLMEENECLRQELAQARMELAEAHSARDELLHQMKRLALGQLQRP", "length": 1465 }, "evidence": [ { "id": "A0A8V0YBB2", "url": "https://omabrowser.org/oma/group/A0A8V0YBB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0JNW5-1", "protein_name": "Bridge-like lipid transfer protein family member 3B", "gene_name": "BLTP3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNAHWEHGDLRFTRIQDPQRGEVLTFKEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSMAPEPTQSSTVVASAQQVKTTQTSNAPDVNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHAKEKESNRRITGGAMQLSFTQLTIDYYPYHKAGDSCNHWMYFSDATKTKNGWANELLHEFECNVEMLKQAVKDHNVGSPPKSPTHASPQHTQTEKDYPLKGTCRTPSVLSQQSKAKLMSSSVVVRLADFNIYQVSTAEQCRSSPKSMICCNKKSLYLPQEMSAVYIEFTEYYYPDGKDFPIPSPNLYSQLNALQFTVDERSILWLNQFLLDLKQSLNQFMAVYKLNDNSKSDEHVDVRVDGLMLKFVIPSEVKSECHQDQPRAISIQSSEMIATNTRHCPNCRHSDLEALFQDFKDCDFFSKTYTSFPKSCDNFNLLHPIFQRHAHEQDTKMHEIYKGNITPQLNKNTLKTSAATDVWAVYFSQFWIDYEGMKSGKGRPISFVDSFPLSIWICQPTRYAESQKEPQTCNQVSLNTSQSESSDLAGRLKRKKLLKEYYSTESEPLTNGGQKPSSSDTFFRFSPSSSEADIHLLVHVHKHVSMQINHYQYLLLLFLHESLILLSENLRKDVEAVTGSPASQTSICIGILLRSAELALLLHPVDQANTLKSPVSESVSPVVPDYLPTENGDFLSSKRKQISRDINRIRSVTVNHMSDNRSMSVDLSHIPLKDPLLFKSASDTNLQKGISFMDYLSDKHLGKISEDESSGLVYKSGSGEIGSETSDKKDSFYTDSSSILNYREDSNILSFDSDGNQNILSSTLTSKGNETIESIFKAEDLLPEAASLSENLDISKEETPPVRTLKSQSSLSGKPKERCPPNLAPLCVSYKNMKRSSSQMSLDTISLDSMILEEQLLESDGSDSHMFLEKGNKKNSTTNYRGTAESVNAGANLQNYGETSPDAISTNSEGAQENHDDLMSVVVFKITGVNGEIDIRGEDTEICLQVNQVTPDQLGNISLRHYLCNRPVGSDQKAVIHSKSSPEISLRFESGPGAVIHSLLAEKNGFLQCHIENFSTEFLTSSLMNIQHFLEDETVATVMPMKIQVSNTKINLKDDSPRSSTVSLEPAPVTVHIDHLVVERSDDGSFHIRDSHMLNTGNDLKENVKSDSVLLTSGKYDLKKQRSVTQATQTSPGVPWPSQSANFPEFSFDFTREQLMEENESLKQELAKAKMALAEAHLEKDALLHHIKKMTVE", "length": 1464 }, "evidence": [ { "id": "A0A8V0YBB2", "url": "https://omabrowser.org/oma/group/A0A8V0YBB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A2RSJ4-1", "protein_name": "Bridge-like lipid transfer protein family member 3B", "gene_name": "Bltp3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAISKVFCNKASIRIPWTKLKTQPICLSLDKVIMEMSTCEEPRAPNGPSPIATASGQSEYGFAEKVVEGITVSVNSIVIRIGAKAFNASFELSQLRIYSVNAQWEHGDLRFTRIQDPQRGEVLTFKEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSMAPEPTQSSTVTSSAQHVKTPQAANAPDLSDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHAKEKESNRRVSGGAMQLSFTQLTIDYYPYHKAGDSCSHWMYFSDATKTKNGWANELLHEFECNVEMLKQAMKDRNLGSPPKSPTHASPQHTQTEKDSTLKGTPKTPSVLPQPSKAKLMSSSVVVRLADFNIYQVSTAEQCRSSPKSMISCNKKSLYLPQEMSAIYIEFTEYYYPDGKDFPIPSPNLYSQLNALQFTVDERSILWLNQFLLDLKQSLNQFMAVYKLNDSSKSDEHVDIRVDGLMLKFVIPSEVKAGCHQDQPHTVSIQSSEMIATNTRHCPNCRHSDLEALCQDFKECDFFSKTYTRFPKSCDSFNLLHPIFQRHAHEQDTKMHEVYKGNIIPKLNKNTLKTSAATDVWAVYFSQFWIDYEGMKSGKGRPVSFVDAFPLSIWICQPTRYAELQKEFQTCDQVTLNTSQSESSDLAGRMKRKKLLKEYYSTESEPLTNGGQRPSSDTFLRFSSSSSDADVHVLVRVHKHVSMQINHYQYLLLLFIHESLVLLSDTLRRDVEAVIGSPASQTSVCVGILLRSAELALLLHPVNPTSALRSPASESGSPLLPDFLPAENGGFLSSKRKQGGSGIHRIRNATLNHMSDNRSMSVDLSHAPLKDPLLFKSASDTNLQKGTSFLDYLSDKHLGKISEDESSGLSHKSGSGEMTSEGSHTKDVASTDSDSVLNYRDGSTRLSLDDDGNHNPPSNPVTGKGIDAIHSIFRAEDFLPEAASLSENPESSKEEAPPARAPKSQTSLSAKSKERCPPSPAPLSVSYKNMKRSASQVSLDTLSLDSMVLEEQAESDGSDSHVLLGKAMKRNSNTSCQSPAESVNTSANTQTCGEASPEAVSTNSEGTQENRDDLMSVVVFRITGVNGEIDIRGEDTEVCLQVNQVTPSQLGNVSLRHYLGNRPVGSDQKAIIHPKSSPEISLRFESGPGAVVHSLLAEKNGFLQCHIENFTTEFLTSSLLNIQHFLEDETVATVMPMKIQVSNTKINLKDDSPRGSTVSLQPSPVTVHIDRLVVERSDDGSFHIRDSHLFNTGTDFKDGASSDSVVRTRGMCDVRMHSSVTQATQTSPEVPLPSQSANFLDITREQLMEENECLRQRLAQAKMELAEAHSARDELLHQMKRMGL", "length": 1457 }, "evidence": [ { "id": "A0A8V0YBB2", "url": "https://omabrowser.org/oma/group/A0A8V0YBB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M9PEM2-1", "protein_name": "UHRF1-binding protein 1-like", "gene_name": "Dm_2L:23546", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVSLIKNQLLKHLSIYTKNLSSDKINLSTFRGEGELSNLELDERVLTELLELPSWLRLTSAWCNHVSFRISWTKLKSVPITLTLDEVRITIETCNPTTRDAGGGSGAGGAGSPTAAASAALPQVPQGKYSFIHKVVDGITIVVNTVNVNFVSAAFTASVQMSRIRVESKTPKWANADLRLTRLKDAQKGIILIFKELSWQTVRIEASSTQDKSLTPLRLLTNHARCRITIRKRLSDCSLLASRLVLILDDLLWVLTDSQLKAALHFVDSLSGLIKAATHATQKTKAARKMQTLPEYKAQVEQQQNRLSESAHTTNAQRMFNAFDVRETSYHFFSQRIDLHLCDDEGDGRSSYPDLDKGGALQVSVTAFQVDYYPYHLAKSDRSHWAKYKEASVAPALWLKESLNAFREAVLNLSQPNRPATHAPLERSTPASPIMLSASMLGSQHGAGSFSNGSSTPTAAGLAAGSGGSAGSGTASMNSQFSQAAQQRSTLENLAKLMSSCVILRIEDFTLYRVTTSGKKAMPKEFVSGDKDRYSFPAEMPIIHAEYTYFYYPGDFVFPLPPSKVFVHVNPIQVHFDLSSILWLNSFGLNLHESLLRTSVGSQSTLHPQQQLPRGSIASNGSNGTQMAAVNVEQEPNLMYMDVKVEAIMPRIVMEAALDAPSQKDRPKTMQIQVSRFALTNIREMGSSRADLAQALHSLQEGSLVFGSGFPSKEGDMCIVTDRILSHVAASDVSMMSPVSPTGQQLPRSASTQYLSRYVMWLEPRDVWCIKLDPVWVDFLGARSLGPNKSIPFVDAVPITLWLHSGSAQAQLDVGKSGTAGSMESMGMPPLPTLPPLQPCNPFLSDEDVRLAGVASGASPPAPAPDRTADVHAIAHISNLVSLQIDHYQLLFLLRLAEELNEMSTFLNLDAERILQKQNEQKSIIFGCVVPQIEVTLVMPSPTPGKESSGGDAESVVPDSASLGDDLHMNSGNITWPTPPPLDQLKSNTFGSVETPSPVTNEPPFDNGIHISNPNTHGYNVQIQSTPTMASSTASQGSRPDTGISTQSQSQTQSISSASKSAKSAAARSGATDTVPSLTKEINSGLLSMKKGFSSFMTSIDSAIKSGTPNDDASDTFSIQSDISSDSDNFANVLGDDKTMDCMDVMFRLNPFTTDNMKASPVEVASEVYEEQPSSYKTNMSSPSEPSEGSTWRRRDLVSMATFRLTTVELIRQQEGPKSSVRLQVAAVSCDECGAIPWDELQIARQANKTKFGARCKAWNLAPYNPEAPPCIRMRLEETLNMPKEIEGIIDRKRIQSWITHHAEIRVKDINMDLSMSTVIGLGDLAEDEVISPPMPLTVNLENVRINLLEDRPPVNITSPGPIPINLCIGRMRLERDQSGLLNIQPIDTNMSDAQHQALGSALFGAPRERDRELLSMQLVMQQMKLDNDQLRRQLVDSKVNTDNYRHKTKQEADVLRSYLKAAQDDISILLEEKKALLDTIRSLQVQLTSSNMSRKSDGNRXHNCMDCIQCCGENNNA", "length": 1518 }, "evidence": [ { "id": "A0A8V0YBB2", "url": "https://omabrowser.org/oma/group/A0A8V0YBB2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2" } ], "pmid": "" }, { "name": "lipid transfer activity", "id": "GO:0120013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2" } ], "pmid": "" }, { "name": "GARP complex binding", "id": "GO:0062069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1226, "end_pos": 1228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1235, "end_pos": 1237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1284, "end_pos": 1286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1373, "end_pos": 1375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1226, "end_pos": 1228 }, { "start_pos": 1235, "end_pos": 1237 }, { "start_pos": 1284, "end_pos": 1286 }, { "start_pos": 1373, "end_pos": 1375 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 912, "end_pos": 914 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBC6-1", "uniprot_ac": "A0A8V0YBC6", "uniprot_id": "A0A8V0YBC6_CHICK", "mass": { "chemical_mass": 38257.0, "monoisotopic_mass": 38257.0 }, "refseq": { "ac": "XP_004944806", "name": "RELT-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944806" }, "gene_names": [ { "name": "RELL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YBC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6" } ] }, { "name": "RELL2", "type": "synonym", "evidence": [ { "id": "XP_004944806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944806" } ] } ], "protein_names": [ { "name": "RELT like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YBC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6/entry#names_and_taxonomy" } ] }, { "name": "RELT-like protein 2", "type": "synonym", "evidence": [ { "id": "XP_004944806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944806" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944806.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944806" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RELL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6", "locus": { "chromosome": "13", "start_pos": 1570746, "end_pos": 1561888, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011491", "url": "https://www.ensembl.org/id/ENSGALG00010011491" } ] } } ], "crossref": [ { "id": "A0A8V0YBC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "416198", "url": "https://www.ncbi.nlm.nih.gov/gene/416198", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416198", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416198", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MSMPALG", "url": "https://omabrowser.org/oma/group/MSMPALG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBC6", "url": "https://www.orthodb.org/?gene=A0A8V0YBC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31481:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31481:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944806", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDQSSSEDGESNSQHSLYMVFLLVLVFFIMGLVGFLICHVLKKKGYRCRTFRDELDPDNKDVLAELQATEEEELNEDTVEKIVRCIIQNEANAEALKEMLGDNDGDIAVPMPSLCPHRNSQDGGPPHHHTVHLGSTQAPCIHCSKRRRHPLHRQGRSKDGKGRMHPGETTVFSVGRFRVTHIGKKTAFHEQQDGAQPNGSKEPSTEELEHSSERFQREQAHNGTVLTGSLENGAVREGTQGSKGMEQSRTGTPVPGTAVGSSPGSTSRQRRLLSRRVLGGSSPSIPGQLGQEETGLGSADEVSDIHGSLSLHEVPDEMGREDSSRRQPGAENMRQQEPSAVVHDRGATV", "length": 350, "header": "tr|A0A8V0YBC6-1|A0A8V0YBC6_CHICK Isoform 1 of RELT like 2 OS=Gallus gallus OX=9031 GN=RELL2 PE=3 SV=1 CANONICAL=A0A8V0YBC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6/entry#A0A8V0YBC6-1", "sequence": { "sequence": "MSDQSSSEDGESNSQHSLYMVFLLVLVFFIMGLVGFLICHVLKKKGYRCRTFRDELDPDNKDVLAELQATEEEELNEDTVEKIVRCIIQNEANAEALKEMLGDNDGDIAVPMPSLCPHRNSQDGGPPHHHTVHLGSTQAPCIHCSKRRRHPLHRQGRSKDGKGRMHPGETTVFSVGRFRVTHIGKKTAFHEQQDGAQPNGSKEPSTEELEHSSERFQREQAHNGTVLTGSLENGAVREGTQGSKGMEQSRTGTPVPGTAVGSSPGSTSRQRRLLSRRVLGGSSPSIPGQLGQEETGLGSADEVSDIHGSLSLHEVPDEMGREDSSRRQPGAENMRQQEPSAVVHDRGATV", "length": 350, "header": "tr|A0A8V0YBC6-1|A0A8V0YBC6_CHICK Isoform 1 of RELT like 2 OS=Gallus gallus OX=9031 GN=RELL2 PE=3 SV=1 CANONICAL=A0A8V0YBC6-1" }, "locus": { "chromosome": "13", "start_pos": 1570043, "end_pos": 1562611, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027517.1", "url": "https://www.ensembl.org/id/ENSGALT00010027517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015758.1", "url": "https://www.ensembl.org/id/ENSGALP00010015758.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416198", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416198", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6" } ], "pmid": "" }, { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 223, "end_pos": 225 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBF1-1", "uniprot_ac": "A0A8V0YBF1", "uniprot_id": "A0A8V0YBF1_CHICK", "mass": { "chemical_mass": 63810.0, "monoisotopic_mass": 63810.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ribonuclease H", "type": "recommended", "evidence": [ { "id": "A0A8V0YBF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1/entry#names_and_taxonomy" } ] }, { "name": "3.1.26.4", "type": "synonym", "evidence": [ { "id": "A0A8V0YBF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1", "locus": {} } ], "crossref": [ { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQLESQGVISKIHSPFNSPIWPVRKASGEWRLMVDYHGLNEVTPPLSAAVPDMLELQYELESKAAKWYATIDIANAFFSIPLATECRPQFAFTWRGVQYTWNRLPQGWKHSPTICHELIQAALEQGGAPEHLQYIDDIIVWGNTESEVFEKGEQVIQILLSAGFAIKRSKVKGPAQEIQFLGIKWQDGRSLIVSPLYQVTRKKNDFTWGPEQQQAFEQIKQEIAGAVALGPVRTEQDVKNILYTAAGEKGPTWSLWQRAAGETRGRTLGLWNRDYRGSEEHYTPTEKEILAAYEGVRAASEVVGTETQLHLAPRLPVLNWMFKGKIPSTHHATDATWSTWIALITQRARMGNLSRPGILEVIMDWSEGKKFGTSPGEEVSRATVVPPYNELPENENKYALFTDGSCRIVGKHRKWKAAVWNPTGQVAEATEGKGESSQFAEVKAIQLALDVAEREWWPMLYLYTDSWMVANALWGWLHQWEQNNWQRRGKPIWAAELWKDIAARIKNIVVKVHHVDAHVPNNRATEEQQNNHQVDRAARIEVAQIDLDWQNKTELFLAR", "length": 560, "header": "tr|A0A8V0YBF1-1|A0A8V0YBF1_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YBF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1/entry#A0A8V0YBF1-1", "sequence": { "sequence": "MRQLESQGVISKIHSPFNSPIWPVRKASGEWRLMVDYHGLNEVTPPLSAAVPDMLELQYELESKAAKWYATIDIANAFFSIPLATECRPQFAFTWRGVQYTWNRLPQGWKHSPTICHELIQAALEQGGAPEHLQYIDDIIVWGNTESEVFEKGEQVIQILLSAGFAIKRSKVKGPAQEIQFLGIKWQDGRSLIVSPLYQVTRKKNDFTWGPEQQQAFEQIKQEIAGAVALGPVRTEQDVKNILYTAAGEKGPTWSLWQRAAGETRGRTLGLWNRDYRGSEEHYTPTEKEILAAYEGVRAASEVVGTETQLHLAPRLPVLNWMFKGKIPSTHHATDATWSTWIALITQRARMGNLSRPGILEVIMDWSEGKKFGTSPGEEVSRATVVPPYNELPENENKYALFTDGSCRIVGKHRKWKAAVWNPTGQVAEATEGKGESSQFAEVKAIQLALDVAEREWWPMLYLYTDSWMVANALWGWLHQWEQNNWQRRGKPIWAAELWKDIAARIKNIVVKVHHVDAHVPNNRATEEQQNNHQVDRAARIEVAQIDLDWQNKTELFLAR", "length": 560, "header": "tr|A0A8V0YBF1-1|A0A8V0YBF1_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YBF1-1" }, "locus": { "chromosome": "W", "start_pos": 2304761, "end_pos": 2304201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028396.1", "url": "https://www.ensembl.org/id/ENSGALT00010028396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016279.1", "url": "https://www.ensembl.org/id/ENSGALP00010016279.1" } ] } }, { "isoform_ac": "A0A8V0YCS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1/entry#A0A8V0YCS0-1", "sequence": { "sequence": "MCWRLNCLTGKDWQKHPIVTGPGAPCILGIDYLRRGYFKDPKGYRWAFGIAAVDTEGVKQLSALPGLSEDTSVVGLLQVKEQQVPIATKTVHRRQYRTNRDSLLPVLKLMRQLESQGVISKIHSPFNSPIWPVRKASGEWRLMVDYHGLNEVTPPLSAAVPDMLELQYELESKAAKWYA", "length": 179, "header": "tr|A0A8V0YCS0-1|A0A8V0YBF1_CHICK Computationally mapped isoform of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=2 CANONICAL=A0A8V0YBF1-1" }, "locus": { "chromosome": "W", "start_pos": 2284646, "end_pos": 2284110, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028394.1", "url": "https://www.ensembl.org/id/ENSGALT00010028394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016277.1", "url": "https://www.ensembl.org/id/ENSGALP00010016277.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA metabolic process", "id": "GO:0006259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 395, "end_pos": 544, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YBF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF1" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 186, "start_aa": "Glu", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 }, { "start_pos": 552, "end_pos": 554 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"uniprot_ac": "A0A8V0YBF7", "uniprot_id": "A0A8V0YBF7_CHICK", "mass": { "chemical_mass": 29987.0, "monoisotopic_mass": 29987.0 }, "refseq": {}, "gene_names": [ { "name": "U2AF1", "type": "recommended", "evidence": [ { "id": "A0A8V0YBF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7" } ] } ], "protein_names": [ { "name": "U2 small nuclear RNA auxiliary factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YBF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "U2AF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7", "locus": { "chromosome": "1", "start_pos": 109817299, "end_pos": 109833156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011880", "url": "https://www.ensembl.org/id/ENSGALG00010011880" } ] } } ], "crossref": [ { "id": "A0A8V0YBF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016198", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016198", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12538", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12538", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395370", "url": "https://www.ncbi.nlm.nih.gov/gene/395370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MIDTRQA", "url": "https://omabrowser.org/oma/group/MIDTRQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P3U0", "url": "https://www.orthodb.org/?gene=A0A1D5P3U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBF7", "url": "https://www.orthodb.org/?gene=A0A8V0YBF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P3U0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P3U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGQEIVKDLVDSEPCHFYCMSARKCCSLTKQVHNEIFFKDGLLNKNL", "length": 255, "header": "tr|A0A8V0YBF7-1|A0A8V0YBF7_CHICK Isoform 1 of U2 small nuclear RNA auxiliary factor 1 OS=Gallus gallus OX=9031 GN=U2AF1 PE=1 SV=1 CANONICAL=A0A8V0YBF7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P3U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7/entry#A0A1D5P3U0-1", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQTADGSHCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGRERDRRRSRDRERSGRF", "length": 237, "header": "tr|A0A1D5P3U0-1|A0A1D5P3U0_CHICK Computationally mapped isoform of U2 small nuclear RNA auxiliary factor 1 OS=Gallus gallus OX=9031 GN=U2AF1 PE=1 SV=1 CANONICAL=A0A8V0YBF7-1" }, "locus": { "chromosome": "1", "start_pos": 109833085, "end_pos": 109819989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028409.1", "url": "https://www.ensembl.org/id/ENSGALT00010028409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016287.1", "url": "https://www.ensembl.org/id/ENSGALP00010016287.1" } ] } }, { "isoform_ac": "A0A8V0YBF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7/entry#A0A8V0YBF7-1", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGQEIVKDLVDSEPCHFYCMSARKCCSLTKQVHNEIFFKDGLLNKNL", "length": 255, "header": "tr|A0A8V0YBF7-1|A0A8V0YBF7_CHICK Isoform 1 of U2 small nuclear RNA auxiliary factor 1 OS=Gallus gallus OX=9031 GN=U2AF1 PE=1 SV=1 CANONICAL=A0A8V0YBF7-1" }, "locus": { "chromosome": "1", "start_pos": 109833085, "end_pos": 109819883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028404.1", "url": "https://www.ensembl.org/id/ENSGALT00010028404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016284.1", "url": "https://www.ensembl.org/id/ENSGALP00010016284.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AGI3-1", "protein_name": "U2 small nuclear RNA auxiliary factor 1", "gene_name": "U2AF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQTADGSHCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGRERDRRRSRDRERSGRF", "length": 239 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A1A4K8-1", "protein_name": "Splicing factor U2AF 35 kDa subunit", "gene_name": "U2AF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGRERDRRRSRDRERSGRF", "length": 237 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q01081-1", "protein_name": "Splicing factor U2AF 35 kDa subunit", "gene_name": "U2AF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF", "length": 240 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3KR55-1", "protein_name": "U2 small nuclear RNA auxiliary factor 1", "gene_name": "U2af1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGRERDRRRSRDRERSGRF", "length": 239 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WU68-1", "protein_name": "Splicing factor U2AF 26 kDa subunit", "gene_name": "U2AF1L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFSQTIVLLNLYRNPQNTAQTADGSHCHVSDVEVQEHYDSFFEEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVAELSNRWFNGQAVHGELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISQNLQRQLYGRGPRRRSPPRFHTGHHPRERNHRCSPDHWHGRF", "length": 220 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q94535-1", "protein_name": "Splicing factor U2af 38 kDa subunit", "gene_name": "U2af38", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAKSADGSHLVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRNEADAEKAANDLNNRWFGGRPVYSELSPVTDFREACCRQYEMGECTRSGFCNFMHLKPISRELRRYLYSRRRRARSRSRSPGRRRGSRSRSRSPGRRGGGRGDGVGGGNYLNNERDNMRGNDRGNDRDRRKGGGGGGGGGGGRY", "length": 264 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9D883-1", "protein_name": "Splicing factor U2AF 35 kDa subunit", "gene_name": "U2af1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGRERDRRRSRDRERSGRF", "length": 239 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FMY5-1", "protein_name": "Splicing factor U2af small subunit B", "gene_name": "U2AF35B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEHLASIFGTEKDRVNCPFYFKIGACRHGDRCSRLHNRPTISPTLLLSNMYQRPDMITPGVDPQGQPLDPSKIQDHFEDFYEDIFEELNKFGEVESLNVCDNLADHMIGNVYVLFKEEDHAAAALQALQGRFYSGRPIIADFSPVTDFREATCRQYEENSCNRGGYCNFMHVKQISRELRRKLFGRYRRSYRRGSRSRSRSISPRRKREHSRERERGDVRDRDRHGNGKRSSDRSERHDRDGGGRRRHGSPKRSRSPRNVREGSEERRARIEQWNRERDEGV", "length": 283 }, "evidence": [ { "id": "A0A8V0YBF7", "url": "https://omabrowser.org/oma/group/A0A8V0YBF7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7" } ], "pmid": "" }, { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7" } ], "pmid": "" }, { "name": "RS domain binding", "id": "GO:0050733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050733", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBF7" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3/entry#names_and_taxonomy" } ] }, { "name": "protein reprimo", "type": "synonym", "evidence": [ { "id": "XP_015145655", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145655" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145655.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145655", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145655" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPRM", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3", "locus": { "chromosome": "7", "start_pos": 35239589, "end_pos": 35239936, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011002", "url": "https://www.ensembl.org/id/ENSGALG00010011002" } ] } } ], "crossref": [ { "id": "A0A8V0YBH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "419946", 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"categories": [ "Protein Classification" ] }, { "id": "PF27763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145655", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145655", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGSAGGGTAAAGLVAGAGSAALELERALRCCTAASAVTDGGGGGGAAAAAADERSLYIMRVVQIAVMCVLALTVVFGIFFLGCNLLIKSEGMINFLVKDRRPSKEVEAVVVGPY", "length": 115, "header": "tr|A0A8V0YBH3-1|A0A8V0YBH3_CHICK Isoform 1 of Reprimo, TP53 dependent G2 arrest mediator homolog OS=Gallus gallus OX=9031 GN=RPRM PE=3 SV=1 CANONICAL=A0A8V0YBH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3/entry#A0A8V0YBH3-1", "sequence": { "sequence": "MNGSAGGGTAAAGLVAGAGSAALELERALRCCTAASAVTDGGGGGGAAAAAADERSLYIMRVVQIAVMCVLALTVVFGIFFLGCNLLIKSEGMINFLVKDRRPSKEVEAVVVGPY", "length": 115, "header": "tr|A0A8V0YBH3-1|A0A8V0YBH3_CHICK Isoform 1 of Reprimo, TP53 dependent G2 arrest mediator homolog OS=Gallus gallus OX=9031 GN=RPRM PE=3 SV=1 CANONICAL=A0A8V0YBH3-1" }, "locus": { "chromosome": "7", "start_pos": 35239936, "end_pos": 35239592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026367.1", "url": "https://www.ensembl.org/id/ENSGALT00010026367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014991.1", "url": "https://www.ensembl.org/id/ENSGALP00010014991.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419946", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419946", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q502I1-1", "protein_name": "Protein reprimo A", "gene_name": "rprma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSTFNQTDSGIFSNRTEENLLCCNFSSVVTDNGFAAAAPDERSLFIMRIVQIAVMCVLSLTVVFGIFFLGCNLLIKSEGMINFLVTDRRPSKEVEAVIVGAY", "length": 103 }, "evidence": [ { "id": "A0A8V0YBH3", "url": "https://omabrowser.org/oma/group/A0A8V0YBH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBH8-1", "uniprot_ac": "A0A8V0YBH8", "uniprot_id": "A0A8V0YBH8_CHICK", "mass": { "chemical_mass": 30352.0, "monoisotopic_mass": 30352.0 }, "refseq": {}, "gene_names": [ { "name": "GLIPR1L", "type": "recommended", "evidence": [ { "id": "A0A8V0YBH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8" } ] } ], "protein_names": [ { "name": "GLI pathosis-related 1-like", "type": "synonym", "evidence": [ { "id": "A0A8V0YBH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLIPR1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8", "locus": { "chromosome": "1", "start_pos": 37901352, "end_pos": 37893017, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012966", "url": "https://www.ensembl.org/id/ENSGALG00010012966" } ] } } ], "crossref": [ { "id": "A0A8V0YBH8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBH8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBH8", "url": "https://www.orthodb.org/?gene=A0A8V0YBH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHU6", "url": "https://www.orthodb.org/?gene=A0A8V0YHU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJV3", "url": "https://www.orthodb.org/?gene=A0A8V0YJV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPM7", "url": "https://www.orthodb.org/?gene=A0A8V0YPM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPP4", "url": "https://www.orthodb.org/?gene=A0A8V0YPP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISRLFTCVLALLHFCLSSGLYQPETLPDIGDAEFIEECVRTHNRFRSGVNPPASNMLYMSWDPDLAKTARGWAKRCEFKHNIYLQEPGQAHPRFTPVGENIWTGSLSIFSVQDAITSWYKEVRDYTYTTNSCSRICGHYTQVVWAQSYKVGCAVHFCPTVSYFSGTNAAHFICNYGPAGNYRWHPYGTGAACSKCNGERCTDNLCRNTKRDKVISDSRWHPAWDRPACDEYCISVVVLRLLLLILTIVATWILPKYWSIAPATKSF", "length": 267, "header": "tr|A0A8V0YBH8-1|A0A8V0YBH8_CHICK Isoform 1 of GLI pathosis-related 1-like OS=Gallus gallus OX=9031 GN=GLIPR1L PE=1 SV=1 CANONICAL=A0A8V0YBH8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8/entry#A0A8V0YBH8-1", "sequence": { "sequence": "MISRLFTCVLALLHFCLSSGLYQPETLPDIGDAEFIEECVRTHNRFRSGVNPPASNMLYMSWDPDLAKTARGWAKRCEFKHNIYLQEPGQAHPRFTPVGENIWTGSLSIFSVQDAITSWYKEVRDYTYTTNSCSRICGHYTQVVWAQSYKVGCAVHFCPTVSYFSGTNAAHFICNYGPAGNYRWHPYGTGAACSKCNGERCTDNLCRNTKRDKVISDSRWHPAWDRPACDEYCISVVVLRLLLLILTIVATWILPKYWSIAPATKSF", "length": 267, "header": "tr|A0A8V0YBH8-1|A0A8V0YBH8_CHICK Isoform 1 of GLI pathosis-related 1-like OS=Gallus gallus OX=9031 GN=GLIPR1L PE=1 SV=1 CANONICAL=A0A8V0YBH8-1" }, "locus": { "chromosome": "1", "start_pos": 37900348, "end_pos": 37893123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031130.1", "url": "https://www.ensembl.org/id/ENSGALT00010031130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018123.1", "url": "https://www.ensembl.org/id/ENSGALP00010018123.1" } ] } }, { "isoform_ac": "A0A8V0YHU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8/entry#A0A8V0YHU6-1", "sequence": { "sequence": "MISRLFTCVLALLHFCLSSGLYQPETLPDIGDAEFIEECVRTHNRFRSGVNPPASNMLYMSWDPDLAKTARGWAKRCEFKHNIYLQEPGQAHPRFTPVGENIWTGSLSIFSVQDAITSWYKEVRDYTYTTNSCSRICGHYTQEIPSVTKSSVIPGGTQPGTDLPAMNTASPWLF", "length": 174, "header": "tr|A0A8V0YHU6-1|A0A8V0YBH8_CHICK Computationally mapped isoform of GLI pathosis-related 1-like OS=Gallus gallus OX=9031 GN=GLIPR1L PE=1 SV=1 CANONICAL=A0A8V0YBH8-1" }, "locus": { "chromosome": "1", "start_pos": 37900157, "end_pos": 37893123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031116.1", "url": "https://www.ensembl.org/id/ENSGALT00010031116.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018110.1", "url": "https://www.ensembl.org/id/ENSGALP00010018110.1" } ] } }, { "isoform_ac": "A0A8V0YJV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8/entry#A0A8V0YJV3-1", "sequence": { "sequence": "MISRLFTCVLALLHFCLSSGLYQPETLPDIGDAEFIEECVRTHNRFRSGVNPPASNMLYMSWDPDLAKTARGWAKRCEFKHNIYLQEPGQAHPRFTPVGENIWTGSLSIFSVQDAITSWYKEVRDYTYTTNSCSRICGHYTQVVWAQSYKVGCAVHFCPTVSYFSGTNAAHFICNYGPAKYQA", "length": 183, "header": "tr|A0A8V0YJV3-1|A0A8V0YBH8_CHICK Computationally mapped isoform of GLI pathosis-related 1-like OS=Gallus gallus OX=9031 GN=GLIPR1L PE=1 SV=1 CANONICAL=A0A8V0YBH8-1" }, "locus": { "chromosome": "1", "start_pos": 37899992, "end_pos": 37893123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031122.1", "url": "https://www.ensembl.org/id/ENSGALT00010031122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018116.1", "url": "https://www.ensembl.org/id/ENSGALP00010018116.1" } ] } }, { "isoform_ac": "A0A8V0YPM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8/entry#A0A8V0YPM7-1", "sequence": { "sequence": "MISRLFTCVLALLHFCLSSGLYQPETLPDIGDAEFIEECVRTHNRFRSGVNPPASNMLYMSWDPDLAKTARGWAKRCEFKHNIYLQEPGQAHPRFTPVGENIWTGSLSIFSVQDAITSWYKEVRDYTYTTNSCSRICGHYTQWELQMAPIWDRSSMQQMQRRAVH", "length": 165, "header": "tr|A0A8V0YPM7-1|A0A8V0YBH8_CHICK Computationally mapped isoform of GLI pathosis-related 1-like OS=Gallus gallus OX=9031 GN=GLIPR1L PE=1 SV=1 CANONICAL=A0A8V0YBH8-1" }, "locus": { "chromosome": "1", "start_pos": 37899447, "end_pos": 37893123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031110.1", "url": "https://www.ensembl.org/id/ENSGALT00010031110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018104.1", "url": "https://www.ensembl.org/id/ENSGALP00010018104.1" } ] } }, { "isoform_ac": "A0A8V0YPP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8/entry#A0A8V0YPP4-1", "sequence": { "sequence": "MISRLFTCVLALLHFCLSSGLYQPETLPDIGDAEFIEECVRTHNRFRSGVNPPASNMLYMSWDPDLAKTARGWAKRCEFKQTTHIPPIAVAEYVAITHRSFGLKATRLDVLSTSVPQCHTSQEPMQHISSATMGQLGITDGTHMGQEQHAANATASGALIICVEIPSVTKSSVIPGGTQPGTDLPAMNTASPWLF", "length": 195, "header": "tr|A0A8V0YPP4-1|A0A8V0YBH8_CHICK Computationally mapped isoform of GLI pathosis-related 1-like OS=Gallus gallus OX=9031 GN=GLIPR1L PE=1 SV=1 CANONICAL=A0A8V0YBH8-1" }, "locus": { "chromosome": "1", "start_pos": 37900157, "end_pos": 37893123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031125.1", "url": "https://www.ensembl.org/id/ENSGALT00010031125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018119.1", "url": "https://www.ensembl.org/id/ENSGALP00010018119.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBH8" }, { "id": "SM00198", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00198" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCP", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 184, "start_aa": "Glu", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBI2-1", "uniprot_ac": "A0A8V0YBI2", "uniprot_id": "A0A8V0YBI2_CHICK", "mass": { "chemical_mass": 37957.0, "monoisotopic_mass": 37957.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Transmembrane protein 64", "type": "synonym", "evidence": [ { "id": "A0A8V0YBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2", "locus": {} } ], "crossref": [ { "id": "A0A8V0YBI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR032816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46593:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46593:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGAGAAALQLLSRAVRQGARQELGRWLSRAAGTAAGGGGDPGGFVPAEAGGLLLGPYAEQGGLPPAELLLCPLPEAGGGGPGLAEARGWRCSCCLLGTCWCKSCLSVCLLAALCFASLALVRQYLRDLLLWAESLDSLAGVLLFTVGFIVVSFPCGWGYILLNVAAGYLYGFVLGMGLMVLGVLVGTFVAHVACRRLLARWALDRIQGSTTLSAVVRVVEGGSGLKVVALARLTPIPFGLQNAVFAVTDLSLPNYLMASSVGLLPTQLLNSYLGTTLRTMEDVIAEQSVSGYLIFSLQIVISIGLMFYVVHRAQVELNAAIVACEMEMKTSLVKDCQPSISGSTTYCNKRTVAFSGGGVNIV", "length": 363, "header": "tr|A0A8V0YBI2-1|A0A8V0YBI2_CHICK Isoform 1 of Transmembrane protein 64 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YBI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2/entry#A0A8V0YBI2-1", "sequence": { "sequence": "MWGAGAAALQLLSRAVRQGARQELGRWLSRAAGTAAGGGGDPGGFVPAEAGGLLLGPYAEQGGLPPAELLLCPLPEAGGGGPGLAEARGWRCSCCLLGTCWCKSCLSVCLLAALCFASLALVRQYLRDLLLWAESLDSLAGVLLFTVGFIVVSFPCGWGYILLNVAAGYLYGFVLGMGLMVLGVLVGTFVAHVACRRLLARWALDRIQGSTTLSAVVRVVEGGSGLKVVALARLTPIPFGLQNAVFAVTDLSLPNYLMASSVGLLPTQLLNSYLGTTLRTMEDVIAEQSVSGYLIFSLQIVISIGLMFYVVHRAQVELNAAIVACEMEMKTSLVKDCQPSISGSTTYCNKRTVAFSGGGVNIV", "length": 363, "header": "tr|A0A8V0YBI2-1|A0A8V0YBI2_CHICK Isoform 1 of Transmembrane protein 64 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YBI2-1" }, "locus": { "chromosome": "2", "start_pos": 124213852, "end_pos": 124203819, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026377.1", "url": "https://www.ensembl.org/id/ENSGALT00010026377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015001.1", "url": "https://www.ensembl.org/id/ENSGALP00010015001.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": 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cytosolic calcium ion concentration", "id": "GO:0051480", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051480", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2" } ], "pmid": "" }, { "name": "positive regulation of bone resorption", "id": "GO:0045780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045780", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2" } ], "pmid": "" }, { "name": "negative regulation of osteoblast differentiation", "id": "GO:0045668", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045668", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2" } ], "pmid": "" }, { "name": "positive regulation of osteoclast differentiation", "id": "GO:0045672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI2" }, { "id": "PF09335", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VTT", "eco_id": "ECO_0000259", "start_pos": 161, "end_pos": 276, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBI3-1", "uniprot_ac": "A0A8V0YBI3", "uniprot_id": "A0A8V0YBI3_CHICK", "mass": { "chemical_mass": 39376.0, "monoisotopic_mass": 39376.0 }, "refseq": { "ac": "NP_001376506", "name": "stomatin-like protein 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506" }, "gene_names": [ { "name": "STOML2", "type": "recommended", "evidence": [ { "id": "A0A8V0YBI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ] }, { "name": "STOML2Z", "type": "synonym", "evidence": [ { "id": "NP_001376506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506" } ] }, { "name": "STOML2", "type": "synonym", "evidence": [ { "id": "NP_001376506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506" } ] } ], "protein_names": [ { "name": "Stomatin-like protein 2, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0YBI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3/entry#names_and_taxonomy" } ] }, { "name": "stomatin (EPB72)-like 2", "type": "synonym", "evidence": [ { "id": "NP_001376506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506" } ] }, { "name": "stomatin like 2-Z", "type": "synonym", "evidence": [ { "id": "NP_001376506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506" } ] }, { "name": "stomatin-like protein 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001376506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX932823.1, CR386500.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000087.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376506", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506" } ] }, { "annotation": "Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3#function" }, { "database": "UniProtKB", "id": "ARBA00060171", "url": "https://www.uniprot.org/uniprotkb/ARBA00060171#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STOML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3", "locus": { "chromosome": "Z", "start_pos": 9137427, "end_pos": 9143375, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011544", "url": "https://www.ensembl.org/id/ENSGALG00010011544" } ] } } ], "crossref": [ { "id": "A0A8V0YBI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427412", "url": "https://www.ncbi.nlm.nih.gov/gene/427412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YLQMLPK", "url": "https://omabrowser.org/oma/group/YLQMLPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBI3", "url": "https://www.orthodb.org/?gene=A0A8V0YBI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43327", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43327", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43327:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43327:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8949664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840373", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840373", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376506", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAQAARRAGPGLLRRAPVVKQPAWLAPAPQRLNSGLPVNIGVLFVPQQEAWVVERMGKFHRILEPGLNFLIPLLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRVMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDRVFRERESLNANIVDAINQASDCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGQKQAQILASEAEKAEQINKAAGEANAMLVRAKAKAEAIQLLAAALAQQHGSAAASLSVAEQYVSAFSKLAKDSNTVLLPTNTGDVTHMVAQALGIYTTLTKTQAVKTRDELPPAHGDPQIPSTEMLKSEQVTSS", "length": 359, "header": "tr|A0A8V0YBI3-1|A0A8V0YBI3_CHICK Isoform 1 of Stomatin-like protein 2, mitochondrial OS=Gallus gallus OX=9031 GN=STOML2 PE=1 SV=1 CANONICAL=A0A8V0YBI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3/entry#A0A8V0YBI3-1", "sequence": { "sequence": "MLAQAARRAGPGLLRRAPVVKQPAWLAPAPQRLNSGLPVNIGVLFVPQQEAWVVERMGKFHRILEPGLNFLIPLLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRVMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDRVFRERESLNANIVDAINQASDCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGQKQAQILASEAEKAEQINKAAGEANAMLVRAKAKAEAIQLLAAALAQQHGSAAASLSVAEQYVSAFSKLAKDSNTVLLPTNTGDVTHMVAQALGIYTTLTKTQAVKTRDELPPAHGDPQIPSTEMLKSEQVTSS", "length": 359, "header": "tr|A0A8V0YBI3-1|A0A8V0YBI3_CHICK Isoform 1 of Stomatin-like protein 2, mitochondrial OS=Gallus gallus OX=9031 GN=STOML2 PE=1 SV=1 CANONICAL=A0A8V0YBI3-1" }, "locus": { "chromosome": "Z", "start_pos": 9143310, "end_pos": 9137614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027622.1", "url": "https://www.ensembl.org/id/ENSGALT00010027622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015823.1", "url": "https://www.ensembl.org/id/ENSGALP00010015823.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8949664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8949664", "resource": "Reactome", "description": "Processing of SMDT1" }, { "id": "R-GGA-9840373", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840373", "resource": "Reactome", "description": "Cellular response to mitochondrial stress" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W169-1", "protein_name": "Stomatin-like protein 2, mitochondrial", "gene_name": "STOML2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLARAARGTGALLLRGSVQASGRAPRRSSSGLPRNTVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMVAQAMGVYGALTKAPVPGPQDSVSSRSSRDVQGTDASLDEELDRVKLS", "length": 356 }, "evidence": [ { "id": "A0A8V0YBI3", "url": "https://omabrowser.org/oma/group/A0A8V0YBI3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4FZT0-1", "protein_name": "Stomatin-like protein 2, mitochondrial", "gene_name": "Stoml2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLARAARGTGALLLRGSVQASGRIPRRASSGLPRNTVILFVPQQEAWVVERMGRFHRILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAPVPGAQNSSEARRDVQTTDTSIEELGRVKLS", "length": 353 }, "evidence": [ { "id": "A0A8V0YBI3", "url": "https://omabrowser.org/oma/group/A0A8V0YBI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99JB2-1", "protein_name": "Stomatin-like protein 2, mitochondrial", "gene_name": "Stoml2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLARAARGTGALLLRGSVQASGRVPRRASSGLPRNTVILFVPQQEAWVVERMGRFHRILEPGLNVLIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAPVPGAQNSSQSRRDVQATDTSIEELGRVKLS", "length": 353 }, "evidence": [ { "id": "A0A8V0YBI3", "url": "https://omabrowser.org/oma/group/A0A8V0YBI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJZ1-1", "protein_name": "Stomatin-like protein 2, mitochondrial", "gene_name": "STOML2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLARAARGTGALLLRGSLLASGRAPRRASSGLPRNTVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMVAQAMGVYGALTKAPVPGTPDSLSSGSSRDVQGTDASLDEELDRVKMS", "length": 356 }, "evidence": [ { "id": "A0A8V0YBI3", "url": "https://omabrowser.org/oma/group/A0A8V0YBI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1F7-1", "protein_name": "Stomatin like 2, isoform A", "gene_name": "Stoml2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRFLLNKRFVPSLVQQDFLLAGSWIPSQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVADKIKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSELGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRAAILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSHLDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVSNSNQATKSSENVKGVGACLNAKSVEYKELQEDKSSVKMNIE", "length": 366 }, "evidence": [ { "id": "A0A8V0YBI3", "url": "https://omabrowser.org/oma/group/A0A8V0YBI3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "CD4-positive, alpha-beta T cell activation", "id": "GO:0035710", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035710", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "lipid localization", "id": "GO:0010876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010876", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "stress-induced mitochondrial fusion", "id": "GO:1990046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "protein complex oligomerization", "id": "GO:0051259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "mitochondrial protein processing", "id": "GO:0034982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "positive regulation of interleukin-2 production", "id": "GO:0032743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "proton motive force-driven mitochondrial ATP synthesis", "id": "GO:0042776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "T cell receptor binding", "id": "GO:0042608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042608", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" }, { "name": "cardiolipin binding", "id": "GO:1901612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBI3", "database": "UniProtKB", "url": 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"TVRQALGGDAGQRQGRLKYLDFLSTFSSEKAATPPATDDSAKAQRGSSVPEVSEGGRSAGSSPTRNLRTGSKQQSHPCSPVGAALPLQNCELIENKLRKRLQGCWRKFLRECKDRDAGKRGEIAPADFLALAEKFNLDINRDECQQLIVKYDLKNDGTFAYCSFIQSCVLLLRAKESSLLQRMKIQNANKMKEAGAETSSFYCALLRIQPRIAHCWRPMRRAFKAHDQGGTGFLSVADFRKVLRQYSVILSEEEFFHVLEHYDKTLSAKIPYNDFLRAFLQ", "length": 281 }, "evidence": [ { "id": "A0A8V0YBL1", "url": "https://omabrowser.org/oma/group/A0A8V0YBL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL1" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 218, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBL4-1", "uniprot_ac": "A0A8V0YBL4", "uniprot_id": "A0A8V0YBL4_CHICK", "mass": { "chemical_mass": 26611.0, "monoisotopic_mass": 26611.0 }, "refseq": { "ac": "XP_004937733", "name": "apolipoprotein L domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937733" }, "gene_names": [ { "name": "APOLD1", "type": "recommended", "evidence": [ { "id": "A0A8V0YBL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ] }, { "name": "APOLD1", "type": "synonym", "evidence": [ { "id": "XP_004937733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937733" } ] } ], "protein_names": [ { "name": "Apolipoprotein L domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YBL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4/entry#names_and_taxonomy" } ] }, { "name": "apolipoprotein L domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_004937733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937733" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937733.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937733" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APOLD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4", "locus": { "chromosome": "1", "start_pos": 48240616, "end_pos": 48230028, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009659", "url": "https://www.ensembl.org/id/ENSGALG00010009659" } ] } } ], "crossref": [ { "id": "769889", "url": "https://www.ncbi.nlm.nih.gov/gene/769889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769889", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769889", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMDEVCE", "url": "https://omabrowser.org/oma/group/AMDEVCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBL4", "url": "https://www.orthodb.org/?gene=A0A8V0YBL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14096:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14096:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937733", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERNGTARPQTPDPTHHFHVALLDQRRRLRGHIAHLHKAARKINKLRKRSLIGNISGSSLTAVGAVTAIVGLSLSPATLGASLLASAVGLGLATAGGAVSITSDLSAVLCNSQEVKKVQEIAVTCRKQMREILGCLEFLRRGQGPGDPKLLQSEKRASISLYNSVCFMVFCGSHSFLVPEYTKEVTKVSQAMLKAKIQKLAANLEICTRAMDEVCELLESRTELSPRMRKLSLGARTTTETPRPSS", "length": 246, "header": "tr|A0A8V0YBL4-1|A0A8V0YBL4_CHICK Isoform 1 of Apolipoprotein L domain containing 1 OS=Gallus gallus OX=9031 GN=APOLD1 PE=3 SV=1 CANONICAL=A0A8V0YBL4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4/entry#A0A8V0YBL4-1", "sequence": { "sequence": "MERNGTARPQTPDPTHHFHVALLDQRRRLRGHIAHLHKAARKINKLRKRSLIGNISGSSLTAVGAVTAIVGLSLSPATLGASLLASAVGLGLATAGGAVSITSDLSAVLCNSQEVKKVQEIAVTCRKQMREILGCLEFLRRGQGPGDPKLLQSEKRASISLYNSVCFMVFCGSHSFLVPEYTKEVTKVSQAMLKAKIQKLAANLEICTRAMDEVCELLESRTELSPRMRKLSLGARTTTETPRPSS", "length": 246, "header": "tr|A0A8V0YBL4-1|A0A8V0YBL4_CHICK Isoform 1 of Apolipoprotein L domain containing 1 OS=Gallus gallus OX=9031 GN=APOLD1 PE=3 SV=1 CANONICAL=A0A8V0YBL4-1" }, "locus": { "chromosome": "1", "start_pos": 48234177, "end_pos": 48233440, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023045.1", "url": "https://www.ensembl.org/id/ENSGALT00010023045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013333.1", "url": "https://www.ensembl.org/id/ENSGALP00010013333.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769889", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769889", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZUT8-1", "protein_name": "Apolipoprotein L domain containing 1", "gene_name": "APOLD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGMEGPVARELQGADALRRFQLLLDRRGRLHGQLLSLREVARRLERLRRRSLAANVTGSALSAAGAVAAIVGLSLSPVTLGVSLLASAVGLGVATAGGVVTITSDLSLIFCNSRELRRVQEIVATCQDQMRELLSCLDFFCRGQDRRDRQLLQCGRNASIALYNSVYFIIFFGSRGFLIPRRAEGATKVSQAVLKAKIQKLAESLESCTGALDELSEQLESRAQLCTKSSRGHDLKISADQPAGLFL", "length": 247 }, "evidence": [ { "id": "A0A8V0YBL4", "url": "https://omabrowser.org/oma/group/A0A8V0YBL4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9Q0X2-1", "protein_name": "Apolipoprotein L domain containing 1", "gene_name": "Apold1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRAAWEPQGADALRRFQGLLLDRRGRLHSQVLRLREVARRLERLRRRSLAANVAGSSLSAAGALAAIVGLSLSPVTLGASLVASAVGLGVATAGGAVTITSDLSLIFCNSREVRRVQEIAATCQDQMRELLSCLEFFCQWQGRRDRQLLQSGRDASMALYNSVYFIVFFGSRGFLIPRRAEGATKVSQAVLKAKIQKLSESLESCTGALDELSEQLESRVQLCTKAGRGHNLRISTDLDAALFF", "length": 246 }, "evidence": [ { "id": "A0A8V0YBL4", "url": "https://omabrowser.org/oma/group/A0A8V0YBL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B959-1", "protein_name": "Apolipoprotein L domain-containing protein 1", "gene_name": "Apold1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKWTAWEPQGADALRRFQGLLLDRRGRLHCQVLRLREVARRLERLRRRSLAANVAGSSLSAAGALAAIVGLSLSPVTLGASLVASAVGLGVATAGGAVTITSDLSLIFCNSREVRRVQEIAATCQDQMRELLSCLEFFCQWQGRGDRQLLQSGRDASMALYNSVYFIVFFGSRGFLIPRRAEGATKVSQAVLKAKIQKLSESLESCTGALDELSEQLESRVQLCTKAGRGHNLRNSPDLDAALFF", "length": 246 }, "evidence": [ { "id": "A0A8V0YBL4", "url": "https://omabrowser.org/oma/group/A0A8V0YBL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96LR9-1", "protein_name": "Apolipoprotein L domain-containing protein 1", "gene_name": "APOLD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRAPCHRLRARGTRKARAGAWRGCTFPCLGKGMERPAAREPHGPDALRRFQGLLLDRRGRLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLVSAVGLGVATAGGAVTITSDLSLIFCNSRELRRVQEIAATCQDQMREILSCLEFFCRWQGCGDRQLLQCGRNASIALYNSVYFIVFFGSRGFLIPRRAEGDTKVSQAVLKAKIQKLAESLESCTGALDELSEQLESRVQLCTKSSRGHDLKISADQRAGLFF", "length": 279 }, "evidence": [ { "id": "A0A8V0YBL4", "url": "https://omabrowser.org/oma/group/A0A8V0YBL4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of membrane permeability", "id": "GO:0090559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "lipoprotein metabolic process", "id": "GO:0042157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "regulation of endothelial cell differentiation", "id": "GO:0045601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "autophagosome-dependent secretion", "id": "GO:0160192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" }, { "name": "Weibel-Palade body", "id": "GO:0033093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033093", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBL8-1", "uniprot_ac": "A0A8V0YBL8", "uniprot_id": "A0A8V0YBL8_CHICK", "mass": { "chemical_mass": 34269.0, "monoisotopic_mass": 34269.0 }, "refseq": { "ac": "NP_001376332", "name": "uncharacterized protein C8orf48 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376332" }, "gene_names": [ { "name": "C8orf48", "type": "recommended", "evidence": [ { "id": "A0A8V0YBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL8" } ] }, { "name": "C4H8orf48", "type": "synonym", "evidence": [ { "id": "NP_001376332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376332" } ] }, { "name": "C8orf48", "type": "synonym", "evidence": [ { "id": "NP_001376332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376332" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C8orf48 homolog", "type": "synonym", "evidence": [ { "id": "NP_001376332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376332" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: ERR2365563.139745.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000071.1. On Dec 1, 2021 this sequence version replaced NP_001376332.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376332" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C8orf48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL8", "locus": { "chromosome": "4", "start_pos": 11495301, "end_pos": 11535451, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011909", "url": "https://www.ensembl.org/id/ENSGALG00010011909" } ] } } ], "crossref": [ { "id": "A0A8V0YBL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "119765002", "url": "https://www.ncbi.nlm.nih.gov/gene/119765002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQCPSCN", "url": "https://omabrowser.org/oma/group/SQCPSCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBL8", "url": "https://www.orthodb.org/?gene=A0A8V0YBL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35256:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35256:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTTSSDRSADYEKQQKELSQSYGSSVLDYSEDTWEPFSEEEVACCQHESKSSELYCSTEDTKHSAVLDPWESMLTLAGRSHAEKQSEVVDSAAAERDFTGKLIDVLKNKEAGIKQEKFVIKTHAEITELSEEELDALQSFCIIKIRRVLPELISKQASGGKSRKQQHGLISKASEANDLTCLVPDGLMNRIRLKNFRETIKQVTEAQVHKSSLCPDCKKKKAELAEIAFLRQKKILMERALLREKLEEQIYSRDVLKLIGETLRSLPKLSEDPRNLWQKLKGKAEGTTAFCEHLKSSASLKE", "length": 303, "header": "tr|A0A8V0YBL8-1|A0A8V0YBL8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C8orf48 PE=4 SV=1 CANONICAL=A0A8V0YBL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBL8/entry#A0A8V0YBL8-1", "sequence": { "sequence": "MTTTSSDRSADYEKQQKELSQSYGSSVLDYSEDTWEPFSEEEVACCQHESKSSELYCSTEDTKHSAVLDPWESMLTLAGRSHAEKQSEVVDSAAAERDFTGKLIDVLKNKEAGIKQEKFVIKTHAEITELSEEELDALQSFCIIKIRRVLPELISKQASGGKSRKQQHGLISKASEANDLTCLVPDGLMNRIRLKNFRETIKQVTEAQVHKSSLCPDCKKKKAELAEIAFLRQKKILMERALLREKLEEQIYSRDVLKLIGETLRSLPKLSEDPRNLWQKLKGKAEGTTAFCEHLKSSASLKE", "length": 303, "header": "tr|A0A8V0YBL8-1|A0A8V0YBL8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=C8orf48 PE=4 SV=1 CANONICAL=A0A8V0YBL8-1" }, "locus": { "chromosome": "4", "start_pos": 11531622, "end_pos": 11507907, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028478.1", "url": "https://www.ensembl.org/id/ENSGALT00010028478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016341.1", "url": "https://www.ensembl.org/id/ENSGALP00010016341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5XVC1-1", "protein_name": "Similar to human chromosome 8 open reading frame 48", "gene_name": "C16h8orf48", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPAQKPGDSKEEYGGPAQTDVCATQVSEEFPKSCTDEVLSSGSISFSGDLQSCSHTSESPPETETPTTSSEEQDELSELSVLQDENKLSEKWINHLKSKEIHSERYQSDLRHLPEIPKASAEELNALRSFCTKKVNSIHQREDSRGKKSNRPKRLQLKWIAETSEVDPFNCTIPDELLNRIYLENTRATLAYIGAITQHNSSQCPSCTSKRAELAQSDFLRRRKTLLQSLLLQEKIDEHLHTTDFLTRIGEAHQDFPRLSDDPRIIWKRLTEKMQKGSSGSGQACSKQV", "length": 292 }, "evidence": [ { "id": "A0A8V0YBL8", "url": "https://omabrowser.org/oma/group/A0A8V0YBL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3N1H0-1", "protein_name": "Chromosome 27 C8orf48 homolog", "gene_name": "C27H8orf48", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADLSKETLESLTDEVKSSGSFSSSGVLQPWSYASGSKSESGSLPSRSEYGDNQSELSDFKANVKKLSRKWIHNLKGKETNSEQYRPDTNHQTEITQASPEELNALQSFCTVKVNLIHHRANSKGKKSSRHKKLQLGPEAEAPEVDALKCTVPDELLNRIYFKNMRTTPKQVGTAKQHISSRCPDCIRKRAELAQSAFLKQKKTLLESLLLQEKIDEHLHTQDFLTLVREAHQSLPRLSDDPRRIWERLNERKVKLETLVFERSDIKQKM", "length": 270 }, "evidence": [ { "id": "A0A8V0YBL8", "url": "https://omabrowser.org/oma/group/A0A8V0YBL8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TTJ4-1", "protein_name": "Uncharacterized protein C8orf48 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGWPPAQKPEDSKEEHGGPAQTDVCATQVSEEFPGSCADEVLSSGSISFSGELQSYSHTSESPVETKTPTTSSEEQDEQSELSLLQKDENKLSEMWINHLKSKEIHSERSQPDRRLPPEIPKESAEELDALQSFCTKKVNLIHQRQDLRAKKSNRPKRLQLRWIAETSEVDAFNCTIPDELWNRIYLENTRATLAYIGAITQHISSQCPSCNSKRAELAQSDFLRRRKTLLQSLLLQEKIDEHLHTTDFLTRVGEAHQGFPRLSDDPRIIWKRLTEKMLKGSSGFGRAYSKQV", "length": 293 }, "evidence": [ { "id": "A0A8V0YBL8", "url": "https://omabrowser.org/oma/group/A0A8V0YBL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96LL4-1", "protein_name": "Uncharacterized protein C8orf48", "gene_name": "C8orf48", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAICPELAQTDKSALANLSDETETLKNSTDEVQTSSSFSSSGGRQSSPLTSGSKLEREKQTPSLEQGDTQSELLDYKNYEKKLSKKWINYLKLKDSNFERHQPDTKLPTEITRVSDEELNALQSYCTMKINLIHRRGDSKKKTSSRHKKLHLGLDVEASERDAFSCTVPDELLNRIYFKNMRTTPKQEAAAKQHISYQCPYCNRKRAELALSAFLKQKKTLLESFLLQERIDEHLHTKDFLTRIGEAHQDFPRLSDDPRIIWKRLTEKSHIRYSGFERSETEQKLQRDGNSACHLPFSLPFLKRLTLIKPELVIVNDNV", "length": 319 }, "evidence": [ { "id": "A0A8V0YBL8", "url": "https://omabrowser.org/oma/group/A0A8V0YBL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBM6-1", "uniprot_ac": "A0A8V0YBM6", "uniprot_id": "A0A8V0YBM6_CHICK", "mass": { "chemical_mass": 53831.0, "monoisotopic_mass": 53831.0 }, "refseq": {}, "gene_names": [ { "name": "NAPEPLD", "type": "recommended", "evidence": [ { "id": "A0A8V0YBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ] } ], "protein_names": [ { "name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "type": "recommended", "evidence": [ { "id": "A0A8V0YBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.54", "type": "synonym", "evidence": [ { "id": "A0A8V0YBM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "D-type phospholipase that hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce bioactive N-acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid. Cleaves the terminal phosphodiester bond of diacyl- and alkenylacyl-NAPEs, primarily playing a role in the generation of long-chain saturated and monounsaturated NAEs in the brain. May control NAPE homeostasis in dopaminergic neuron membranes and regulate neuron survival, partly through RAC1 activation. As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis by promoting cold-induced brown or beige adipocyte differentiation program to generate heat from fatty acids and glucose. Has limited D-type phospholipase activity toward N-acyl lyso-NAPEs.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN1#function" }, { "database": "UniProtKB", "id": "ARBA00045525", "url": "https://www.uniprot.org/uniprotkb/ARBA00045525#function" }, { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAPEPLD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6", "locus": { "chromosome": "1", "start_pos": 13125207, "end_pos": 13144967, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009658", "url": "https://www.ensembl.org/id/ENSGALG00010009658" } ] } } ], "crossref": [ { "id": "A0A8V0YBM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "417719", "url": "https://www.ncbi.nlm.nih.gov/gene/417719", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417719", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417719", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHWTRRT", "url": "https://omabrowser.org/oma/group/QHWTRRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBM6", "url": "https://www.orthodb.org/?gene=A0A8V0YBM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBN1", "url": "https://www.orthodb.org/?gene=A0A8V0YBN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15032:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15032:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "45528", "url": "https://www.rhea-db.org/rhea/45528", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45532", "url": "https://www.rhea-db.org/rhea/45532", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45536", "url": "https://www.rhea-db.org/rhea/45536", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45540", "url": "https://www.rhea-db.org/rhea/45540", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45544", "url": "https://www.rhea-db.org/rhea/45544", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45552", "url": "https://www.rhea-db.org/rhea/45552", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45556", "url": "https://www.rhea-db.org/rhea/45556", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45592", "url": "https://www.rhea-db.org/rhea/45592", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45596", "url": "https://www.rhea-db.org/rhea/45596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45608", "url": "https://www.rhea-db.org/rhea/45608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45612", "url": "https://www.rhea-db.org/rhea/45612", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45616", "url": "https://www.rhea-db.org/rhea/45616", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45620", "url": "https://www.rhea-db.org/rhea/45620", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53164", "url": "https://www.rhea-db.org/rhea/53164", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56464", "url": "https://www.rhea-db.org/rhea/56464", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56548", "url": "https://www.rhea-db.org/rhea/56548", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGLGSPLCVRCGEEEEVRVGSGTDANSSEWGFDLAQIERDLWPFEEEAFQYCYCLPLCRLSGFEELPQLFPSPLSQKNMDKTEEPAPSASSQYPKEAVRKHHNSDRGSRGSDTSRASRKSFRLDYRLEEDVTKSKRGKDGRFVNPWPTWKSPTLPNVLKWCLMEKDNSNVPSSKQELDKELPVLKPYFVQNPELVGKTGTGMRVTWLGHASVLVEMDELVFLTDPIFSQRASPVQLMGPKRFRPPPCTVDQLPKIDAVVISHTHYDHLDYNTVKSLNERFGSELRWFVPLGLLDWMQRCGCENVIELDWWEENCVPGHDAVTFVFTPSQHWCKRTVTDDNKVLWGSWSVLGPWNRFFFAGDTGYCVAFEQIGKRFGPFDLAAIPIGAYEPRWFMKHQHVDPEEAVRIHIDVQAKKSVAIHWGTFALANEYYLDPPVKLNEALERYGLKKEDFFVLNHGESQDLSTNDGSE", "length": 471, "header": "tr|A0A8V0YBM6-1|A0A8V0YBM6_CHICK Isoform 1 of N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D OS=Gallus gallus OX=9031 GN=NAPEPLD PE=3 SV=1 CANONICAL=A0A8V0YBM6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6/entry#A0A8V0YBM6-1", "sequence": { "sequence": "MGGLGSPLCVRCGEEEEVRVGSGTDANSSEWGFDLAQIERDLWPFEEEAFQYCYCLPLCRLSGFEELPQLFPSPLSQKNMDKTEEPAPSASSQYPKEAVRKHHNSDRGSRGSDTSRASRKSFRLDYRLEEDVTKSKRGKDGRFVNPWPTWKSPTLPNVLKWCLMEKDNSNVPSSKQELDKELPVLKPYFVQNPELVGKTGTGMRVTWLGHASVLVEMDELVFLTDPIFSQRASPVQLMGPKRFRPPPCTVDQLPKIDAVVISHTHYDHLDYNTVKSLNERFGSELRWFVPLGLLDWMQRCGCENVIELDWWEENCVPGHDAVTFVFTPSQHWCKRTVTDDNKVLWGSWSVLGPWNRFFFAGDTGYCVAFEQIGKRFGPFDLAAIPIGAYEPRWFMKHQHVDPEEAVRIHIDVQAKKSVAIHWGTFALANEYYLDPPVKLNEALERYGLKKEDFFVLNHGESQDLSTNDGSE", "length": 471, "header": "tr|A0A8V0YBM6-1|A0A8V0YBM6_CHICK Isoform 1 of N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D OS=Gallus gallus OX=9031 GN=NAPEPLD PE=3 SV=1 CANONICAL=A0A8V0YBM6-1" }, "locus": { "chromosome": "1", "start_pos": 13143517, "end_pos": 13126211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023059.1", "url": "https://www.ensembl.org/id/ENSGALT00010023059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013343.1", "url": "https://www.ensembl.org/id/ENSGALP00010013343.1" } ] } }, { "isoform_ac": "A0A8V0YBN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6/entry#A0A8V0YBN1-1", "sequence": { "sequence": "MVRGRALWSCCLQLSALPSAVSCACGKPQPFNSSYWRAVEPPRRGWSGTMEEEEEEEDGTARGQRPGSSQKNMDKTEEPAPSASSQYPKEAVRKHHNSDRGSRGSDTSRASRKSFRLDYRLEEDVTKSKRGKDGRFVNPWPTWKSPTLPNVLKWCLMEKDNSNVPSSKQELDKELPVLKPYFVQNPELVGKTGTGMRVTWLGHASVLVEMDELVFLTDPIFSQRASPVQLMGPKRFRPPPCTVDQLPKIDAVVISHTHYDHLDYNTVKSLNERFGSELRWFVPLGLLDWMQRCGCENVIELDWWEENCVPGHDAVTFVFTPSQHWCKRTVTDDNKVLWGSWSVLGPWNRFFFAGDTGYCVAFEQIGKRFGPFDLAAIPIGAYEPRWFMKHQHVDPEEAVRIHIDVQAKKSVAIHWGTFALANEYYLDPPVKLNEALERYGLKKEDFFVLNHGESQDLSTNDGSE", "length": 464, "header": "tr|A0A8V0YBN1-1|A0A8V0YBN1_CHICK Computationally mapped isoform of N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D OS=Gallus gallus OX=9031 GN=NAPEPLD PE=3 SV=1 CANONICAL=A0A8V0YBM6-1" }, "locus": { "chromosome": "1", "start_pos": 13144947, "end_pos": 13126211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023067.1", "url": "https://www.ensembl.org/id/ENSGALT00010023067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013348.1", "url": "https://www.ensembl.org/id/ENSGALP00010013348.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417719", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417719", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8RJ40-1", "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "gene_name": "napepld", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEQPLVGASSSTPLDYRQEADVTCSRRDSQGRFVNPWSTWHFPSYTTVARLFLTEKNNSKIPSAKEALDRELPIVQPYFIQNPDQCGQTGTSVRATWLGHATVLVEMEGLLVLTDPIFSQRASPVAFMGPKRYRDPPCTIEQLPRLDAVVISHTHYDHLDAASVTALNSRFGSALHWFVPLGLAEWMQKTGCENVTELDWWVGSRIPGHDNVSFFCTPAQHWCKRTPVDDNKTLWGSWSIVGSHSRFFFAGDTGYCASFKEIGRHFGPFDLAAIPIGAYVPRGIMKSQHVDPEEAVQIHIDVQAKASLAIHWGTFPLSYEHYLEPPARLREAMVNLGLNPDDFFTLHHGESRMINLKDMHSSS", "length": 364 }, "evidence": [ { "id": "A0A8V0YBM6", "url": "https://omabrowser.org/oma/group/A0A8V0YBM6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A4X1VBA4-1", "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "gene_name": "NAPEPLD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDENESNQSLMTSSQYSKESVRKRQDSRNSGGSDSSRFSRKSFKLDYRLEEDVTKSKKGKDGRFVNPWPTWKNLSIPSVLRWLIMEKDHSSVPCSKEELDKELPVLRPYFIRDPEDAGVREAALRVTWLGHATVMVEMDELIFLTDPVFSARASPSQHMGPKRFRRPPCSIGELPRIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCSAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHIDVQTKRSVAIHWGTFALANEHYLEPPVKLSEALERYGLKTEDFFVLKHGESRYLNTDDENFE", "length": 393 }, "evidence": [ { "id": "A0A8V0YBM6", "url": "https://omabrowser.org/oma/group/A0A8V0YBM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MJ34-1", "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "gene_name": "Napepld", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARRRALTRCVQLWARSAEQGRRRGGRRSAGRGLCGTSGAAWPAASWASAEGTPRHARSLALRTSFSPKDMDENENSQSSTTSYQYPKETVRKRQNSVQNSGGSVSSRFSRKSFKLDYRLEEDVTKSKKGKDGRFVNPWPTWKNISISNVFRWLIMEKDHSSVPVSKEELDKELPVLKPYFISDPKEAGVTEAGLRVTWLGHATLMVEMDELIFLTDPMFSSRASPSQYMGPKRFCGPPCTISELPPIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWSKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEDAVRIHIDVQTKKSVAIHWGTFALANEHYLEPPVKLNEALERYGLKSEDFFVLKHGESRYLNNDKAFEET", "length": 465 }, "evidence": [ { "id": "A0A8V0YBM6", "url": "https://omabrowser.org/oma/group/A0A8V0YBM6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q54BV7-1", "protein_name": "Beta-lactamase-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEEINEEYERIKSSKNKEGRFNNPFGVSGVFPGFSKVVNRIKEIRKFPIIPLTEEERRDIHPCLKPNFELIKQEYDFKTTIKSTWIGHSTVIVQLEGFTFLTDPVWSDRCSPFTSIGPKRHTDPACAISELPKIDFVLISHTHYDHLDYQSVVEIYKLQKPTFYVPLGMKQWFLDAGIFDVFELDWWEEIKFIKNENENENKNENENENKNEIKLIYTPVNHSSRRGLFDKDKALWGGWIVQGEFRRFWFSGDTAYNDKLFKVIGHHYGPFDYSLIAIGAYDRNREIMRANHIDPQEAVMIHREIKSKRSFGIHWGTFTLTNEPILEPPQLLLSESKKQSLKENEFFVSKIGETSIISNDFNQNNNDVN", "length": 369 }, "evidence": [ { "id": "A0A8V0YBM6", "url": "https://omabrowser.org/oma/group/A0A8V0YBM6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q58CN9-1", "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "gene_name": "NAPEPLD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDENETNQLLMTSNQYPKEAVRKRQNSRNSGGSDSSRFSRKSFKLDYRLEEDVTKSKKGKDGRFVNPWPTWKNPSIPSLLRWVITERDHSSVPCSKELDKELPVLKPYFIDDPEEAGVRGAGLRVTWLGHATVMVEMDELILLTDPIFSARASPSQRMGPKRFRRAPCTVEELPRIDAVLVSHNHYDHLDCNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCSAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVKIHIDVQAKKSVAIHWGTFALANEHYLEPPAKLCEALEKYRLKTEDFLVLKHGESRYLNTDDEDVE", "length": 392 }, "evidence": [ { "id": "A0A8V0YBM6", "url": "https://omabrowser.org/oma/group/A0A8V0YBM6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6IQ20-1", "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "gene_name": "NAPEPLD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDENESNQSLMTSSQYPKEAVRKRQNSARNSGASDSSRFSRKSFKLDYRLEEDVTKSKKGKDGRFVNPWPTWKNPSIPNVLRWLIMEKDHSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNNDDENF", "length": 393 }, "evidence": [ { "id": "A0A8V0YBM6", "url": "https://omabrowser.org/oma/group/A0A8V0YBM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BH82-1", "protein_name": "N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D", "gene_name": "Napepld", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEYEDSQSPAPSYQYPKETLRKRQNSVQNSGGSVSSRFSRKSFKLDYRLEEDVTKSKKGKDGRFVNPWPTWKNISIPNVLRWLIMEKNHSGVPGSKEELDKELPVLKPYFVSDPEDAGVREAGLRVTWLGHATLMVEMDELIFLTDPMFSSRASPSQYMGPKRFRRPPCTISELPTIDAVLISHNHYDHLDYGSVLALNERFGSELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLLDDNKVLWGSWSVLGPWSRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHADPEDAVRIHIDLQTKRSVAIHWGTFALANEHYLEPPVKLNEALERYGLSCEDFFILKHGESRYLNTDDRAFEET", "length": 396 }, "evidence": [ { "id": "A0A8V0YBM6", "url": "https://omabrowser.org/oma/group/A0A8V0YBM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "N-acylethanolamine metabolic process", "id": "GO:0070291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070291", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "temperature homeostasis", "id": "GO:0001659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "N-acylphosphatidylethanolamine metabolic process", "id": "GO:0070292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "host-mediated modulation of intestinal microbiota composition", "id": "GO:0048874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "N-acylphosphatidylethanolamine-specific phospholipase D activity", "id": "GO:0070290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070290", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "bile acid binding", "id": "GO:0032052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBM6" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": 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"input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45540", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45540" } ] }, { "id": "45544", "name": "", "equation": "N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45544", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45544" } ] }, { "id": "45552", "name": "", "equation": "N-tetradecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-tetradecanoylethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45552", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45552" } ] }, { "id": "45556", "name": "", "equation": "N-dodecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-dodecanoylethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45556", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45556" } ] }, { "id": "45592", "name": "", "equation": "N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = N-hexadecanoylethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45592", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45592" } ] }, { "id": "45596", "name": "", "equation": "N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + N-hexadecanoylethanolamine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45596" } ] }, { "id": "45608", "name": "", "equation": "N-decanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-decanoyl ethanolamine + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45608" } ] }, { "id": "45612", "name": "", "equation": 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"N-butanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-butanoyl ethanolamine + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "45620", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45620" } ] }, { "id": "53164", "name": "", "equation": "N,1-diacyl-sn-glycero-3-phosphoethanolamine + H2O = an N-acylethanolamine + a 1-acyl-sn-glycero-3-phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YBM6-1" ], "evidence": [ { "id": "53164", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53164" } ] }, { "id": "56464", "name": "", "equation": "1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O = 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRGGEMVYIPDDSDFSSFREQCESAEGWHCRYNKAGVTVWSQGQEESCTVQKIKTRISCKDVSAETLYDVLHDTHYRKKWDSHMIETYDIGRLTVNADVGYYSWKCPSPLKNRDFVTLRSWLPLGNDYIILNYSVKHPKYPPRKDFVRAVSLQTGYLIKANGTSACVLYYLTQVDPRGILSDHGLFSTQWIWALAGSLPKWVVNRVSQFVAPKAMKKIYKAGLKYPEWKRRHDPGYKPWVYPEQNTLPSLSLAELSLQHADSLEHIDETGLSEEHLSASDHEA", "length": 284, "header": "tr|A0A8V0YBN2-1|A0A8V0YBN2_CHICK Isoform 1 of START domain-containing protein 10 OS=Gallus gallus OX=9031 GN=STARD10 PE=4 SV=1 CANONICAL=A0A8V0YBN2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2/entry#A0A8V0YBN2-1", "sequence": { "sequence": "MSRGGEMVYIPDDSDFSSFREQCESAEGWHCRYNKAGVTVWSQGQEESCTVQKIKTRISCKDVSAETLYDVLHDTHYRKKWDSHMIETYDIGRLTVNADVGYYSWKCPSPLKNRDFVTLRSWLPLGNDYIILNYSVKHPKYPPRKDFVRAVSLQTGYLIKANGTSACVLYYLTQVDPRGILSDHGLFSTQWIWALAGSLPKWVVNRVSQFVAPKAMKKIYKAGLKYPEWKRRHDPGYKPWVYPEQNTLPSLSLAELSLQHADSLEHIDETGLSEEHLSASDHEA", "length": 284, "header": "tr|A0A8V0YBN2-1|A0A8V0YBN2_CHICK Isoform 1 of START domain-containing protein 10 OS=Gallus gallus OX=9031 GN=STARD10 PE=4 SV=1 CANONICAL=A0A8V0YBN2-1" }, "locus": { "chromosome": "13", "start_pos": 1603968, "end_pos": 1599333, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027699.1", "url": "https://www.ensembl.org/id/ENSGALT00010027699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015878.1", "url": "https://www.ensembl.org/id/ENSGALP00010015878.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN2" }, { "id": "PS50848", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50848" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "START", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 228, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 162, "end_pos": 164 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBN9-1", "uniprot_ac": "A0A8V0YBN9", "uniprot_id": "A0A8V0YBN9_CHICK", "mass": { "chemical_mass": 70319.0, "monoisotopic_mass": 70319.0 }, "refseq": { "ac": "XP_416360", "name": "solute carrier family 13 member 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416360" }, "gene_names": [ { "name": "SLC13A4", "type": "recommended", "evidence": [ { "id": "A0A8V0YBN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9" } ] }, { "name": "SLC13A4", "type": "synonym", "evidence": [ { "id": "XP_416360", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416360" } ] } ], "protein_names": [ { "name": "Solute carrier family 13 member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YBN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 13 member 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416360", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416360" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_416360.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416360" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC13A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9", "locus": { "chromosome": "1", "start_pos": 58435126, "end_pos": 58407861, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011042", "url": "https://www.ensembl.org/id/ENSGALG00010011042" } ] } } ], "crossref": [ { "id": "A0A8V0YBN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "418127", "url": "https://www.ncbi.nlm.nih.gov/gene/418127", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TFVRQTN", "url": "https://omabrowser.org/oma/group/TFVRQTN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBN9", "url": "https://www.orthodb.org/?gene=A0A8V0YBN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-433137", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433137", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416360", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMVKEILRSRNLLLVVLIPLLLLPLPLLYPCSEASCAYVLIVTAVYWVSEAVPLGAAALIPAFLYPLFGVMKSSEVAAEYFKNTTLLLMGVICVAASVEKWNLHKRIALRMVMMAGAKPGMLLLCFMCCTTVLSMWLSNTSTTAMVMPIVEAVLQELVNAEEEHDVISTTGNTIIEENESIGLNEKHDQPSLELIFINEDATTTDFSSLMHSKTMNSVHMIANPIGTMKSRSNGQHLPQAQILVLPPKPSELDLSTKYQYQSRHDHMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPNAEVVNFGTWFLFSFPISLIMLALTWLWMHWLFLGCNFKETCSVSKKKKTKREEMSERRIHEEYKKLGNVSYPEMVTGFFFILMTLLWFTREPGFVPGWSSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKGKGDAERSTDANTLDPIITWKDFQKTMPWEIVVLVGGGYALAAGCKTSGLSTWIGRQMLSLSSLPYWAVTLLACILVSLVTEFVSNPATITIFLPILCSMSETLLINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNLIGLAVVMVAINTWGIRLFQLNTFPEWAAVSNVTIQT", "length": 633, "header": "tr|A0A8V0YBN9-1|A0A8V0YBN9_CHICK Isoform 1 of Solute carrier family 13 member 4 OS=Gallus gallus OX=9031 GN=SLC13A4 PE=3 SV=1 CANONICAL=A0A8V0YBN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9/entry#A0A8V0YBN9-1", "sequence": { "sequence": "MAMVKEILRSRNLLLVVLIPLLLLPLPLLYPCSEASCAYVLIVTAVYWVSEAVPLGAAALIPAFLYPLFGVMKSSEVAAEYFKNTTLLLMGVICVAASVEKWNLHKRIALRMVMMAGAKPGMLLLCFMCCTTVLSMWLSNTSTTAMVMPIVEAVLQELVNAEEEHDVISTTGNTIIEENESIGLNEKHDQPSLELIFINEDATTTDFSSLMHSKTMNSVHMIANPIGTMKSRSNGQHLPQAQILVLPPKPSELDLSTKYQYQSRHDHMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPNAEVVNFGTWFLFSFPISLIMLALTWLWMHWLFLGCNFKETCSVSKKKKTKREEMSERRIHEEYKKLGNVSYPEMVTGFFFILMTLLWFTREPGFVPGWSSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKGKGDAERSTDANTLDPIITWKDFQKTMPWEIVVLVGGGYALAAGCKTSGLSTWIGRQMLSLSSLPYWAVTLLACILVSLVTEFVSNPATITIFLPILCSMSETLLINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNLIGLAVVMVAINTWGIRLFQLNTFPEWAAVSNVTIQT", "length": 633, "header": "tr|A0A8V0YBN9-1|A0A8V0YBN9_CHICK Isoform 1 of Solute carrier family 13 member 4 OS=Gallus gallus OX=9031 GN=SLC13A4 PE=3 SV=1 CANONICAL=A0A8V0YBN9-1" }, "locus": { "chromosome": "1", "start_pos": 58435115, "end_pos": 58408567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026452.1", "url": "https://www.ensembl.org/id/ENSGALT00010026452.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015058.1", "url": "https://www.ensembl.org/id/ENSGALP00010015058.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-433137", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433137", "resource": "Reactome", "description": "Sodium-coupled sulphate, di- and tri-carboxylate transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SNI6-1", "protein_name": "Solute carrier family 13 member 4", "gene_name": "SLC13A4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLLKGLLRARKLLLIILVPLLLLPLPVLHPSSEAACAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTMLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTMLSMWLSNTSTTAMVMPIVEAVLQELVSAEEEQLVAGNASAEEAELISLKANNSQPSLELIFVNEDTSNADFSSLMMNKNLNGVPTVTSPVKTANHQDQKRHPPQEKPPVPTPRPRNQELKKKYKSQHDQMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPGADVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREELSEKRIQQEYEKLGAVSYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYCTDATVSIFLGFLLFLIPAKKPCFRKKNDGEDQEPSPGMEPIITWKDFQKTMPWEIVILVGGGYALASGSKTSGLSTWIGYQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGINVIGLVIVMVAINTWGINLFHLDTYPAWAKVGNVTDQA", "length": 626 }, "evidence": [ { "id": "A0A8V0YBN9", "url": "https://omabrowser.org/oma/group/A0A8V0YBN9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6R7G2-1", "protein_name": "Solute carrier family 13 member 4", "gene_name": "SLC13A4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLCSPIPPKTGGEEPGFWCRQGLYLPSCSAHKTKEDSWKPRKVGEVFLDGGERRQAAQHLAGAGSEGRRSRMGLLKGLLGARKLLLVILVPLLLLPLPMLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSSEVAGEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEEEQLVAGNSSAEEAEPINLDVNNSQPPLELIFVNEDTSNADFNSLMQNKNRNGVPTVTNSAETANLPGRKQHPSQEKPPVLTPSSRNQELKRKYKSQHDQMICKCLSLSISYAATIGGLTTIIGTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREELSEKRIQEEYEKLGAITYPEMVTGFFFVLMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKRDGEDRGPSLGMESIITWKDFQKTMPWEIVILVGGGYALASGSKTSGLSTWIGQQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPIVCSLSETLQINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVTVMVAINTWGISLFDLNTFPAWAKVSNITDQA", "length": 698 }, "evidence": [ { "id": "A0A8V0YBN9", "url": "https://omabrowser.org/oma/group/A0A8V0YBN9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9UKG4-1", "protein_name": "Solute carrier family 13 member 4", "gene_name": "SLC13A4", 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"UniProtKB", "id": "A0A8V0YBN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQHSNTGPHASLKTIEHAVNLGWTILPHPPYSPDLAPSDFQLFGLMKNGLHGQHFPSTETVTAAVKQWVISNGADFYECSMQDLVLCWQKCIASGGGCVEKILFCS", "length": 106, "header": "tr|A0A8V0YBP4-1|A0A8V0YBP4_CHICK Isoform 1 of Tc1-like transposase DDE domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YBP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP4/entry#A0A8V0YBP4-1", "sequence": { "sequence": "MQHSNTGPHASLKTIEHAVNLGWTILPHPPYSPDLAPSDFQLFGLMKNGLHGQHFPSTETVTAAVKQWVISNGADFYECSMQDLVLCWQKCIASGGGCVEKILFCS", "length": 106, "header": "tr|A0A8V0YBP4-1|A0A8V0YBP4_CHICK Isoform 1 of Tc1-like transposase DDE domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YBP4-1" }, "locus": { "chromosome": "2", "start_pos": 69110240, "end_pos": 69109923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026462.1", "url": "https://www.ensembl.org/id/ENSGALT00010026462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015063.1", "url": "https://www.ensembl.org/id/ENSGALP00010015063.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBP6-1", "uniprot_ac": "A0A8V0YBP6", "uniprot_id": "A0A8V0YBP6_CHICK", "mass": { "chemical_mass": 50442.0, "monoisotopic_mass": 50442.0 }, "refseq": {}, "gene_names": [ { "name": "DCSTAMP", "type": "recommended", "evidence": [ { "id": "A0A8V0YBP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ] } ], "protein_names": [ { "name": "Dendrocyte expressed seven transmembrane protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YBP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCSTAMP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6", "locus": { "chromosome": "2", "start_pos": 129536722, "end_pos": 129533980, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013013", "url": "https://www.ensembl.org/id/ENSGALG00010013013" } ] } } ], "crossref": [ { "id": "A0A8V0YBP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBP6", "url": "https://www.orthodb.org/?gene=A0A8V0YBP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21041:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21041:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVFALAVQSAWGVFASERRPGWKYLTQLFAICSAVGFLLSILLFLSIHISLEQHALFLLSCGLREGRSALLTAGTGVVVAGNIQSIVHNLKVLTDSITCHLEYEKFDLIKYYIEAVKWIYEKANLPNNLLAVTIKHEFTPSYSISDDTLKQELNDTKQEIQRVANQISFMLNILPCIGQKVLPIVGILLVCFGTVLFIKHFVGSHNAKFKNTYITKRFITFDEHQKQQQRPCVLPLNKKERKNYVTIPSFSFTRKERKQMQHFFLPVVIHLCIWLLFAAVDYLFYWLIIYVNKHLQELPDLEIHLRLSQQNIAKNDLLKISLFKNSCVPQPELHLSMTWLQLGTITFFLIIFGLSSGLLTQLKILVSNSFYPDVEMKRIQYLHSKLLKKRTKIQQKAVKNVIVFLYFQVNFWFPILRARETVRKKDKAALNDNMV", "length": 436, "header": "tr|A0A8V0YBP6-1|A0A8V0YBP6_CHICK Isoform 1 of Dendrocyte expressed seven transmembrane protein OS=Gallus gallus OX=9031 GN=DCSTAMP PE=4 SV=1 CANONICAL=A0A8V0YBP6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6/entry#A0A8V0YBP6-1", "sequence": { "sequence": "MGVFALAVQSAWGVFASERRPGWKYLTQLFAICSAVGFLLSILLFLSIHISLEQHALFLLSCGLREGRSALLTAGTGVVVAGNIQSIVHNLKVLTDSITCHLEYEKFDLIKYYIEAVKWIYEKANLPNNLLAVTIKHEFTPSYSISDDTLKQELNDTKQEIQRVANQISFMLNILPCIGQKVLPIVGILLVCFGTVLFIKHFVGSHNAKFKNTYITKRFITFDEHQKQQQRPCVLPLNKKERKNYVTIPSFSFTRKERKQMQHFFLPVVIHLCIWLLFAAVDYLFYWLIIYVNKHLQELPDLEIHLRLSQQNIAKNDLLKISLFKNSCVPQPELHLSMTWLQLGTITFFLIIFGLSSGLLTQLKILVSNSFYPDVEMKRIQYLHSKLLKKRTKIQQKAVKNVIVFLYFQVNFWFPILRARETVRKKDKAALNDNMV", "length": 436, "header": "tr|A0A8V0YBP6-1|A0A8V0YBP6_CHICK Isoform 1 of Dendrocyte expressed seven transmembrane protein OS=Gallus gallus OX=9031 GN=DCSTAMP PE=4 SV=1 CANONICAL=A0A8V0YBP6-1" }, "locus": { "chromosome": "2", "start_pos": 129536719, "end_pos": 129533980, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031217.1", "url": "https://www.ensembl.org/id/ENSGALT00010031217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018189.1", "url": "https://www.ensembl.org/id/ENSGALP00010018189.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "positive regulation of macrophage fusion", "id": "GO:0034241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034241", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "positive regulation of bone resorption", "id": "GO:0045780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045780", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "positive regulation of monocyte differentiation", "id": "GO:0045657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "membrane fusion", "id": "GO:0061025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "myeloid dendritic cell differentiation", "id": "GO:0043011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "cellular response to interleukin-4", "id": "GO:0071353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "osteoclast fusion", "id": "GO:0072675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072675", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" }, { "name": "cellular response to macrophage colony-stimulating factor stimulus", "id": "GO:0036006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP6" }, { "id": "PF07782", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dendritic cell-specific transmembrane protein-like", "eco_id": "ECO_0000259", "start_pos": 210, "end_pos": 384, "start_aa": "Phe", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBP9-1", "uniprot_ac": "A0A8V0YBP9", "uniprot_id": "A0A8V0YBP9_CHICK", "mass": { "chemical_mass": 128445.0, "monoisotopic_mass": 128445.0 }, "refseq": {}, "gene_names": [ { "name": "JARID2", "type": "recommended", "evidence": [ { "id": "A0A8V0YBP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9" } ] } ], "protein_names": [ { "name": "Protein Jumonji", "type": "recommended", "evidence": [ { "id": "A0A8V0YBP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9/entry#names_and_taxonomy" } ] }, { "name": "Jumonji/ARID domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YBP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis. Acts as an accessory subunit for the core PRC2 (Polycomb repressive complex 2) complex, which mediates histone H3K27 (H3K27me3) trimethylation on chromatin. Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, thereby playing a key role in stem cell differentiation and normal embryonic development. In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases. Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5. Participates in the negative regulation of cell proliferation signaling. Does not have histone demethylase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9#function" }, { "database": "UniProtKB", "id": "ARBA00058553", "url": "https://www.uniprot.org/uniprotkb/ARBA00058553#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "JARID2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9", "locus": { "chromosome": "2", "start_pos": 61000666, "end_pos": 60914112, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009678", "url": "https://www.ensembl.org/id/ENSGALG00010009678" } ] } } ], "crossref": [ { "id": "A0A8V0YBP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16870", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16870", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBP9", "url": "https://www.orthodb.org/?gene=A0A8V0YBP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10694:SF113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10694:SF113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02375", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02375", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02928", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02928", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YBP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSLSSTRLSTFRARHKTRPRLQAQRKFAQSQPNSPSTTPIKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPSNMVYFGSSQDDEDEEEEEEETEDTKTATNNASSSCQSTPRKGKTHKQVPNGQVFNGSSKSLKEKEPAQKHKSKEATPGKEKNSEHKAESRKDQAAANHHPTTNTGSSTKGLTANNHHTLHRSAQDLRKQVSKVNGITRMSSPSANAASAKKMRDVRPSPSKTVKYTATVTKGTVTYTKAKKELVKETKLNHHKPSSPVNHTISGKLESSNAKTRKQVLSLGASKSNNTAVNGVKVNGKLNQKTCTKEVGRQLREGLRNSKRRLEETNHIDKIQSPTKRMKGAVNLAEAASKKAVVEKPLLNGHLKKEVPEKNLERNRPKRATAGKSTPGKQAHGKTENASCENRSTSQAESLHKPQDSMGKHEKGSSKSGWGMLGEIPILRPSTKEFHDPLIYIESVRAQVEKYGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACFVQLINEMGGMQQVTDLKKWNKLADMLRIPKTAQDRLAKLQEAYCQYLLSYDSLSPEEHKKLEKEVLLEKEILEKRKGPLEGHSENAYKFHSLPRFEPKNGLINGVVHKNGFRNKLKEVDVPLKTGRRRLFAQEKETTKDDEEEEEEGVLSDLHKCIYKGRSVSLTTFYRTARNIMNMCFTKEPTVAEVEQEYWRLVEQKDSHVAVHCGKVDTNTHGSGFPVGKSEPFSRHGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADCIWYCIPAAEENKLDDVVHTLLQANGTPGLEMLESNVMISPEILCKEGIRVHRTVQQSGQFVVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFKTAKEMKRRRIAKPFSMEKLLYQIATAEAKKENGPTLSTISSLLGELRDTELRQRRQLYEAGLHSSARYGSHDSSSTAMDGKKKPRKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKMMYRYDEEQIISLVNQICGKVSGKNGSIENCISKPTPKRGPRKRATVDVPSSRLSSSSSSKSASS", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2A7", "url": "https://www.uniprot.org/uniprotkb/E1C2A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2A7-1", "url": "https://www.uniprot.org/uniprotkb/E1C2A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSQALGCGEEATFSSHGLFTTWPNTPDGNLSNSLNGLSLMGVLNTRAGGSIQGLQNLKSPRSLSLSEYGPGQHSGALEDCHSLKSVDSGIPTLEVGNPEPVHCNALTAKRKQSEPEIVPDRTFQSACTLPSYVPPRPLTSEHDHAVRKSSTFPRTGYDTVKLYSPTSKTLNRSDDISVCSVSSLSTELSTTLSVSNEDILDFVVTSSSSAIVTLETDEAHFSDVTLSSTKETNEQSQQDCCQETEVDSRQKILGPFTNFLARNLFTRKQNARSEKQNDVGWKLFGKVPLRENSQKDPKKIQKEYEEKTGRAHRPLSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQKRKKQLEERCKLEDSIGNAVLTWNNEILPNWETMCCSRKVRELWWQGIPPSVRGKVWSLAIGNELNITHELYDICLARAKEKWRSRSTVGAEVECEDAGFSTADREASLELIKLDISRTFPNLCIFQQGGPYHDTLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHIAQFLTKLPEDLPSEEFFTSIAAIQMQSRNKKWAQILAALQKDNREMEKGSPSLKH", "length": 715, "header": "tr|A0A8V0YBQ2-1|A0A8V0YBQ2_CHICK Isoform 1 of TBC1 domain family member 14 OS=Gallus gallus OX=9031 GN=TBC1D14 PE=4 SV=1 CANONICAL=A0A8V0YBQ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2/entry#A0A8V0YBQ2-1", "sequence": { "sequence": "MPSQALGCGEEATFSSHGLFTTWPNTPDGNLSNSLNGLSLMGVLNTRAGGSIQGLQNLKSPRSLSLSEYGPGQHSGALEDCHSLKSVDSGIPTLEVGNPEPVHCNALTAKRKQSEPEIVPDRTFQSACTLPSYVPPRPLTSEHDHAVRKSSTFPRTGYDTVKLYSPTSKTLNRSDDISVCSVSSLSTELSTTLSVSNEDILDFVVTSSSSAIVTLETDEAHFSDVTLSSTKETNEQSQQDCCQETEVDSRQKILGPFTNFLARNLFTRKQNARSEKQNDVGWKLFGKVPLRENSQKDPKKIQKEYEEKTGRAHRPLSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQKRKKQLEERCKLEDSIGNAVLTWNNEILPNWETMCCSRKVRELWWQGIPPSVRGKVWSLAIGNELNITHELYDICLARAKEKWRSRSTVGAEVECEDAGFSTADREASLELIKLDISRTFPNLCIFQQGGPYHDTLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHIAQFLTKLPEDLPSEEFFTSIAAIQMQSRNKKWAQILAALQKDNREMEKGSPSLKH", "length": 715, "header": "tr|A0A8V0YBQ2-1|A0A8V0YBQ2_CHICK Isoform 1 of TBC1 domain family member 14 OS=Gallus gallus OX=9031 GN=TBC1D14 PE=4 SV=1 CANONICAL=A0A8V0YBQ2-1" }, "locus": { "chromosome": "4", "start_pos": 79449502, "end_pos": 79387841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027739.1", "url": "https://www.ensembl.org/id/ENSGALT00010027739.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015898.1", "url": "https://www.ensembl.org/id/ENSGALP00010015898.1" } ] } }, { "isoform_ac": "A0A8V0YDY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2/entry#A0A8V0YDY6-1", "sequence": { "sequence": "MAQRERSDGAQRYPVTTWPNTPDGNLSNSLNGLSLMGVLNTRAGGSIQGLQNLKSPRSLSLSEYGPGQHSGALEDCHSLKSVDSGIPTLEVGNPEPVHCNALTAKRKQSEPEIVPDRTFQSACTLPSYVPPRPLTSEHDHAVRKSSTFPRTGYDTVKLYSPTSKTLNRSDDISVCSVSSLSTELSTTLSVSNEDILDFVVTSSSSAIVTLETDEAHFSDVTLSSTKETNEQSQQDCCQETEVDSRQKILGPFTNFLARNLFTRKQNARSEKQNDVGWKLFGKVPLRENSQKDPKKIQKEYEEKTGRAHRPLSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQKRKKQLEERCKLEDSIGNAVLTWNNEILPNWETMCCSRKVRELWWQGIPPSVRGKVWSLAIGNELNITHELYDICLARAKEKWRSRSTVGAEVECEDAGFSTADREASLELIKLDISRTFPNLCIFQQGGPYHDTLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHIAQFLTKLPEDLPSEEFFTSIAAIQMQSRNKKWAQILAALQKDNREMEKGSPSLKH", "length": 710, "header": "tr|A0A8V0YDY6-1|A0A8V0YBQ2_CHICK Computationally mapped isoform of TBC1 domain family member 14 OS=Gallus gallus OX=9031 GN=TBC1D14 PE=4 SV=1 CANONICAL=A0A8V0YBQ2-1" }, "locus": { "chromosome": "4", "start_pos": 79449502, "end_pos": 79387567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027741.1", "url": "https://www.ensembl.org/id/ENSGALT00010027741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015899.1", "url": "https://www.ensembl.org/id/ENSGALP00010015899.1" } ] } }, { "isoform_ac": "A0A8V0YIM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2/entry#A0A8V0YIM7-1", "sequence": { "sequence": "MGVLNTRAGGSIQGLQNLKSPRSLSLSEYGPGQHSGALEDCHSLKSVDSGIPTLEVGNPEPVHCNALTAKRKQSEPEIVPDRTFQSACTLPSYVPPRPLTSEHDHAVRKSSTFPRTGYDTVKLYSPTSKTLNRSDDISVCSVSSLSTELSTTLSVSNEDILDFVVTSSSSAIVTLETDEAHFSDVTLSSTKETNEQSQQDCCQETEVDSRQKILGPFTNFLARNLFTRKQNARSEKQNDVGWKLFGKVPLRENSQKDPKKIQKEYEEKTGRAHRPLSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQKRKKQLEERCKLEDSIGNAVLTWNNEILPNWETMCCSRKVRELWWQGIPPSVRGKVWSLAIGNELNITHELYDICLARAKEKWRSRSTVGAEVECEDAGFSTADREASLELIKLDISRTFPNLCIFQQGGPYHDTLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHIAQFLTKLPEDLPSEEFFTSIAAIQMQSRNKKWAQILAALQKDNREMEKGSPSLKH", "length": 675, "header": "tr|A0A8V0YIM7-1|A0A8V0YBQ2_CHICK Computationally mapped isoform of TBC1 domain family member 14 OS=Gallus gallus OX=9031 GN=TBC1D14 PE=4 SV=1 CANONICAL=A0A8V0YBQ2-1" }, "locus": { "chromosome": "4", "start_pos": 79449502, "end_pos": 79392893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027737.1", "url": "https://www.ensembl.org/id/ENSGALT00010027737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015897.1", "url": "https://www.ensembl.org/id/ENSGALP00010015897.1" } ] } }, { "isoform_ac": "E1C2A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2/entry#E1C2A7-1", "sequence": { "sequence": "MEYEEKTGRAHRPLSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQKRKKQLEERCKLEDSIGNAVLTWNNEILPNWETMCCSRKVRELWWQGIPPSVRGKVWSLAIGNELNITHELYDICLARAKEKWRSRSTVGAEVECEDAGFSTADREASLELIKLDISRTFPNLCIFQQGGPYHDTLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHIAQFLTKLPEDLPSEEFFTSIAAIQMQSRNKKWAQILAALQKDNREMEKGSPSLKH", "length": 413, "header": "tr|E1C2A7-1|E1C2A7_CHICK Computationally mapped isoform of TBC1 domain family member 14 OS=Gallus gallus OX=9031 GN=TBC1D14 PE=4 SV=1 CANONICAL=A0A8V0YBQ2-1" }, "locus": { "chromosome": "4", "start_pos": 79449502, "end_pos": 79421811, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027735.1", "url": "https://www.ensembl.org/id/ENSGALT00010027735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015896.1", "url": "https://www.ensembl.org/id/ENSGALP00010015896.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422862", "resource": "KEGG Pathway" }, { "id": "R-GGA-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "regulation of autophagosome assembly", "id": "GO:2000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "recycling endosome to Golgi transport", "id": "GO:0071955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ2" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 423, "end_pos": 633, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 30, "end_pos": 32 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 598, "end_pos": 600 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBQ5-1", "uniprot_ac": "A0A8V0YBQ5", "uniprot_id": "A0A8V0YBQ5_CHICK", "mass": { "chemical_mass": 86327.0, "monoisotopic_mass": 86327.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Cadherin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ5", "locus": {} } ], "crossref": [ { "id": "A0A8V0YBQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002126", "url": 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"Protein Classification" ] }, { "id": "PTHR24028:SF329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBS6-1", "uniprot_ac": "A0A8V0YBS6", "uniprot_id": "A0A8V0YBS6_CHICK", "mass": { "chemical_mass": 31110.0, "monoisotopic_mass": 31110.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Integrase catalytic domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0YBS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS6", "locus": {} } ], "crossref": [ { "id": "A0A8V0YBS6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41694:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41694:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBS7-1", "uniprot_ac": "A0A8V0YBS7", "uniprot_id": "A0A8V0YBS7_CHICK", "mass": { "chemical_mass": 136062.0, "monoisotopic_mass": 136062.0 }, "refseq": { "ac": "XP_004937872", "name": "WASH complex subunit 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937872" }, "gene_names": [ { "name": "WASHC4", "type": "recommended", "evidence": [ { "id": "A0A8V0YBS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS7" } ] }, { "name": "WASHC4", "type": "synonym", "evidence": [ { "id": "XP_004937872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937872" } ] } ], "protein_names": [ { "name": "WASH complex subunit 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937872" } ] }, { "name": "WASH complex subunit 4", "type": "synonym", "evidence": [ { "id": "A0A8V0YBS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937872.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937872" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WASHC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS7", "locus": { "chromosome": "1", "start_pos": 54292515, "end_pos": 54330848, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011621", "url": "https://www.ensembl.org/id/ENSGALG00010011621" } ] } } ], "crossref": [ { "id": "A0A8V0YBS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "418077", "url": "https://www.ncbi.nlm.nih.gov/gene/418077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418077", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418077", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCNIFIQ", "url": "https://omabrowser.org/oma/group/RCNIFIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBS7", "url": "https://www.orthodb.org/?gene=A0A8V0YBS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31409:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31409:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14745", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14745", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALETLSPEWEFDRLDDGSQKIHAEVQLKNYGKFLEEYASQLKRIEDALDDSVGDVWDFSLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDSSMVEGDCQIQMGRFVSFLQELSCFVTRCYEVVVNVVHQLAVLYTSNKNAPKIIETSGVHFQAMYEHLGELLTVLITLDEIIDNHATLKDHWTMYKRLLKSVHHNPSKFGIQEDKLKPFEKLLLKLECQLLDGMIFQACIEQQFDSINGGVSVSKSSTFAEEFAHTLRTAFANVETKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDVCKKVPAITLTANIIWFADNFLIQKIPAAAKLLDKKSIHTIKTQRENFLQQKAQSLTKDMQSYYVFVSSWMTKMESILSKEQRMDKFAEDLSNRCIVFIQGFLYAYSLSTIIKTTMNLYMSMQKPMTKTSVKALCRLVELLKAIEHMFYRRSMVVADSVTHISQHLQYQALHSISVAKKRVISDKKYSEQRLDVLSALVLAENALNGPSTKQRRLIVSLALSVGTQMKTFKDEELLPLQLVLKKLDLISELTERVRAQCDCCFLYWHRAVFPIYLDDVYENAVDSARLHYMFSALRDCVPAMMHARHLESYEVLLECYDKEIMEVLNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFRVGMKDLAHFFFLNPIRFFNRFIDIKAHVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLSMTEAHLPSQTLEQGLDVLEIMRNIHVFVSRYLYNLNNQIFIERTSNNKHLNTINIRHVANSIRTHGTGIMNTTVNFTYQFLRKKFYIFSQFMYDEHIKSRLIKDIRFFREVKDQNDHKYPFERADKFNRGIRKLGITPDGQSYLDQFRQLISQIGNAMGYVRMIRSGGLHCCSSAIRFVPDLEDIVNFEELVKEEGLSEETQKAARQLDSVLSDLTRNFAEGTEYFKMLVDVFAPEFRSPKNMHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKSGAAFTDDGFAMGVAYILKLLDQYQEFDSLHWFQSVREKYVKEIRAVAKQQNVQSINQDEKLLQTMNLTHKRLEVCLQEFELLYFSLSSARIFFRADKTAAEENQEKKEREEESVKASNGDLSNSTSADPVVK", "length": 1173, "header": "tr|A0A8V0YBS7-1|A0A8V0YBS7_CHICK Isoform 1 of WASH complex subunit 4 OS=Gallus gallus OX=9031 GN=WASHC4 PE=1 SV=1 CANONICAL=A0A8V0YBS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS7/entry#A0A8V0YBS7-1", "sequence": { "sequence": "MALETLSPEWEFDRLDDGSQKIHAEVQLKNYGKFLEEYASQLKRIEDALDDSVGDVWDFSLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDSSMVEGDCQIQMGRFVSFLQELSCFVTRCYEVVVNVVHQLAVLYTSNKNAPKIIETSGVHFQAMYEHLGELLTVLITLDEIIDNHATLKDHWTMYKRLLKSVHHNPSKFGIQEDKLKPFEKLLLKLECQLLDGMIFQACIEQQFDSINGGVSVSKSSTFAEEFAHTLRTAFANVETKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDVCKKVPAITLTANIIWFADNFLIQKIPAAAKLLDKKSIHTIKTQRENFLQQKAQSLTKDMQSYYVFVSSWMTKMESILSKEQRMDKFAEDLSNRCIVFIQGFLYAYSLSTIIKTTMNLYMSMQKPMTKTSVKALCRLVELLKAIEHMFYRRSMVVADSVTHISQHLQYQALHSISVAKKRVISDKKYSEQRLDVLSALVLAENALNGPSTKQRRLIVSLALSVGTQMKTFKDEELLPLQLVLKKLDLISELTERVRAQCDCCFLYWHRAVFPIYLDDVYENAVDSARLHYMFSALRDCVPAMMHARHLESYEVLLECYDKEIMEVLNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFRVGMKDLAHFFFLNPIRFFNRFIDIKAHVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLSMTEAHLPSQTLEQGLDVLEIMRNIHVFVSRYLYNLNNQIFIERTSNNKHLNTINIRHVANSIRTHGTGIMNTTVNFTYQFLRKKFYIFSQFMYDEHIKSRLIKDIRFFREVKDQNDHKYPFERADKFNRGIRKLGITPDGQSYLDQFRQLISQIGNAMGYVRMIRSGGLHCCSSAIRFVPDLEDIVNFEELVKEEGLSEETQKAARQLDSVLSDLTRNFAEGTEYFKMLVDVFAPEFRSPKNMHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKSGAAFTDDGFAMGVAYILKLLDQYQEFDSLHWFQSVREKYVKEIRAVAKQQNVQSINQDEKLLQTMNLTHKRLEVCLQEFELLYFSLSSARIFFRADKTAAEENQEKKEREEESVKASNGDLSNSTSADPVVK", "length": 1173, "header": "tr|A0A8V0YBS7-1|A0A8V0YBS7_CHICK Isoform 1 of WASH complex subunit 4 OS=Gallus gallus OX=9031 GN=WASHC4 PE=1 SV=1 CANONICAL=A0A8V0YBS7-1" }, "locus": { "chromosome": "1", "start_pos": 54330824, "end_pos": 54294935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027778.1", "url": "https://www.ensembl.org/id/ENSGALT00010027778.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015923.1", "url": "https://www.ensembl.org/id/ENSGALP00010015923.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418077", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A7I6-1", "protein_name": "WASH complex subunit 4", "gene_name": "Washc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVDTLSPDWDFDRVDDGSQKIHAEVQLKNYGKFLEEYTSQLRRIEDALDDLVGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKHEAETKFYNGLLFYGEGAADSSMAEGDCQIQMGRFVSFLQELSCFVTRCYEVVMSVIHQLAALYISNKTGPKIIETTGVHFQTMYEHLGELLTVLLTLDEIIDNHVTLKDHWTMYKRLLKSVHHNPSKFGIQEERLKPFEKFLLKLEGQLLDGMIFQACIEQQFDSLNGGISVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDICKKVPAVTLTANIIWFPDNFLIHKMPAAAKLLDRKSLQAIKIHRDAFLQQKAQSLTKDVQSYYVFVSSWMMKMESMLSKEQRTDTFAEDLTNTCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTRTSVKALCRLIELLKAVEHMFHRRSMVVADSVSHITQHLQHQALNSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLVVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHSRHLESHELLLDCYDKEIMDILNERLLDKLCKETEKDLRLSVHTHLKLDDRNPFKVGRKDLALFFSLNPIRFFNRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGITPEGQSYLDQFRQLLSQIGNAMGYIRMIRSGGLHCSSNAIRFVPDLEDIVSFEELVKEEGLAEETLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIRAVAKQQSVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKMSNGDGSESTVSADPVVK", "length": 1173 }, "evidence": [ { "id": "A0A8V0YBS7", "url": "https://omabrowser.org/oma/group/A0A8V0YBS7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F4L4-1", "protein_name": "WASH complex subunit 4 isoform X1", "gene_name": "washc4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVDSLSPDWEFDRFDDGSQKIHTEVQVKNYERFLEEYIAQLQGIEEALDDSIGDVWDFTLDPITLKLLPYEQSSLLELIKTDNKVLNKVITVYAALCCEVKKLKHEAETKFYNGLLYYGEGVSDTSVVEGESQIQMGRFVSFLQELSCFVSRCFEVVVNMVHQLAALYNSSKGATKIIESTGVHFQTVYEHLGELLVVLITLDEIMENHATLKEHWKMYKRLLKSVHHNPAKFAIPEEKLKPFEKLIFKLEGQLLDSMIFQACVEQRFDNPGENVSVSKNSAFAEEFAYNIRTIFANVESKLGEPSEIDQRDKYTGVCGLFVLHFHIFRAVDKKIYKSLLDVCKKVPAVTLAANIIWFPDTFLINKVPAAAKLMDKKSLQSIRSSRDVFLQQKAQTLMKDMQSYYIFVTSWMMKMESILSKEPKPDKLSEDLSNRCNIFVQGILYAYSISTIIKTTMNMYMSMQRPMTKTSVKALCRLVELLKAVEHTFHRRSLVVADSVSHITQQLQSQALVSISMAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKERRLIMSLALSVGTQMKTFKDEELLPLQLVLKKLDLISELRERVKVQCDCSFLYWHRTVFPIYLDDVYENAVDAARIHYMFSALRDCVPTMLHAKHMESCDQLLECYDTEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFKVGMKDLAHFFSLKPIRFFNRFIDIKAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHVFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLRKKFYIFSQFMYDEHIKSRLIKDIRFFRETKDQTDQKYPFERAEKFNRGIRKLGLTPDGQSYLDQFRQLISQIGNAMGYVRMIRSGGLHCCSSAIRFVPDLEDIVNFEELVKEEGLSEETQKASSQLDCVLSDLTSNSAEGTEYFKMLVGVFAPEFRSIKNMHLRNFYMIVPPLTVNFVEHSISCKEKLNKKNKVGAAFTDDGFAMGVAYILKLLDQYQEFDSLHWFQAVREKYVKEMNAVVKEQNVQSTSQDEKLMQTMNLTQKRLDVYLQEFELLYFSLSSARIFFRADKTAAEETQEKKDKEEGAKTGPVSMTAEGSPVEPSAK", "length": 1173 }, "evidence": [ { "id": "A0A8V0YBS7", "url": "https://omabrowser.org/oma/group/A0A8V0YBS7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2M389-1", "protein_name": "WASH complex subunit 4", "gene_name": "WASHC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVETLSPDWEFDRVDDGSQKIHAEVQLKNYGKFLEEYTSQLRRIEDALDDSIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDASMVEGDCQIQMGRFISFLQELSCFVTRCYEVVMNVVHQLAALYISNKIAPKIIETTGVHFQTMYEHLGELLTVLLTLDEIIDNHITLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLLDGMIFQACIEQQFDSLNGGVSVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTIDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIQKIPAAAKLLDRKSLQAIKIHRDTFLQQKAQSLTKDVQSYYVFVSSWMMKMESILSKEQRMDKFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLVELLKAIEHMFYRRSMVVADSVSHITQHLQHQALHSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHARHLESYEILLDCYDKEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFKVGMKDLALFFSLNPIRFFNRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGVTPEGQSYLDQFRQLISQIGNAMGYVRMIRSGGLHCSSNAIRFVPDLEDIVNFEELVKEEGLAEETLKAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYILKLLDQYREFDSLHWFQSVREKYLKEIRAVAKQQNVQSASQDEKLLQTMNLTQKRLDVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSNGDLSDSTVSADPVVK", "length": 1173 }, "evidence": [ { "id": "A0A8V0YBS7", "url": "https://omabrowser.org/oma/group/A0A8V0YBS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UMB9-1", "protein_name": "WASH complex subunit 4", "gene_name": "Washc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVDTLSPDWDFDRVDDGSQKIHAEVQLKNYGRFLEEYTSQLRRIEDALDDLIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDSSMVEGDCQIQMGRFVSFLQELSCFVTRCYEVVMNVIHQLAALYISNKIGPKIIETTGVHFQTMYEHLGELLTVLLTLDEIVDNHVTLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLLDGMIFQACIEQQFDSLNGGISVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIHKMPAAAKLLDRKSLQAIKIHRDTFLQQKAQSLNKDVQSYYVFVSSWMMKMESMLSKEQRMDTFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLIELLKAIEHMFYRRSMVVADSVSHITQHLQHQALSSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQAQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHSRHLESHELLLDCYDKEIMDILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFKVGRKDLALFFSLNPIRFFNRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGITPEGQSYLDQFRQLISQIGNAMGYIRMIRSGGLHCSSNAIRFVPDLEDIVSFEELVKEEGLAEETLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKLGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIRAVAKQQNVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSNGDGPESTVSADPVVK", "length": 1173 }, "evidence": [ { "id": "A0A8V0YBS7", "url": "https://omabrowser.org/oma/group/A0A8V0YBS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54R74-1", "protein_name": "WASH complex subunit 4", "gene_name": "washc4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": 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"database": "Ensembl Peptide", "id": "ENSGALP00010016412.1", "url": "https://www.ensembl.org/id/ENSGALP00010016412.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBS9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": 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"tr|A0A8V0YBT2-1|A0A8V0YBT2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YBT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT2/entry#A0A8V0YBT2-1", "sequence": { "sequence": "MEATTTRTWAVPDLGGEPPSVAVSTKCSSRCSSRSKGLCRTSSAYLSPSSPFSGAREKCEFGERL", "length": 65, "header": "tr|A0A8V0YBT2-1|A0A8V0YBT2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YBT2-1" }, "locus": { "chromosome": "13", "start_pos": 1186471, "end_pos": 1185914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026514.1", "url": "https://www.ensembl.org/id/ENSGALT00010026514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015098.1", "url": "https://www.ensembl.org/id/ENSGALP00010015098.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], 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[] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YBT4-1", "uniprot_ac": "A0A8V0YBT4", "uniprot_id": "A0A8V0YBT4_CHICK", "mass": { "chemical_mass": 72852.0, "monoisotopic_mass": 72852.0 }, "refseq": {}, "gene_names": [ { "name": "TTLL12", "type": "recommended", "evidence": [ { "id": "A0A8V0YBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ] } ], "protein_names": [ { "name": "Tubulin tyrosine ligase like 12", "type": "synonym", "evidence": [ { "id": "A0A8V0YBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTLL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4", "locus": { "chromosome": "1", "start_pos": 68615328, "end_pos": 68635127, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011943", "url": "https://www.ensembl.org/id/ENSGALG00010011943" } ] } } ], "crossref": [ { "id": "A0A8V0YBT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YBT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBT4", "url": "https://www.orthodb.org/?gene=A0A8V0YBT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBT9", "url": "https://www.orthodb.org/?gene=A0A8V0YBT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46088:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46088:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDSSFVRMQAKVVCAFSALYCAYMSTASTNCLYSVHFQVFDAGDYFGIMQVEEVDEEEEGDEAMEDELKKKPNPGNEPCFKVIVTNENGLQASNPDSIFLIDHAWTYRIEHARQQLLHVPGLLHRMANLMGIDFHGEIPDEGSVEQVLQEMWKYNQTYQLSQGTAEEKVPVWYIMDEFGSRIQHSDQPSFATAPLFYMPQQIAYTVLWPLRDLETGDEVTRDYAYGETDRLIRKCVLLPWVPNEVLDVNCFTPEPSDEHYQAILAENKEKLPIAINPSVYDKDKVFKVFTDIQQVLNSLTHPRFVFTDKEAEADILYNFSHFKDYRKLSEERPEVMLNQFPCENLLTVKDCLASISRRAGGPDGPRWLPRTFNLQTELPQFICYFQQRERRGEDNHWICKPWNLARSLDTHITNSLNNIIRHRESSPKVVCKYIENPVLFHREDVGMVKFDIRYVVLLRSVKPLKLYVYDVFWLRFSNRAFSLDDLDDYEKHFTVMNYAPGVTLKQVHCEEFVPQFEKQYPEHLWTTVQANIFKAFAELFQVASAKPAPLGICDYPSSRAIYAIDLMLKWDTSRDGKRIMQPQILEVNFNPDCDRACKYHPTFFNDVFSTLFLDEADNCHVTCIV", "length": 626, "header": "tr|A0A8V0YBT4-1|A0A8V0YBT4_CHICK Isoform 1 of Tubulin tyrosine ligase like 12 OS=Gallus gallus OX=9031 GN=TTLL12 PE=1 SV=1 CANONICAL=A0A8V0YBT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4/entry#A0A8V0YBT4-1", "sequence": { "sequence": "MLDSSFVRMQAKVVCAFSALYCAYMSTASTNCLYSVHFQVFDAGDYFGIMQVEEVDEEEEGDEAMEDELKKKPNPGNEPCFKVIVTNENGLQASNPDSIFLIDHAWTYRIEHARQQLLHVPGLLHRMANLMGIDFHGEIPDEGSVEQVLQEMWKYNQTYQLSQGTAEEKVPVWYIMDEFGSRIQHSDQPSFATAPLFYMPQQIAYTVLWPLRDLETGDEVTRDYAYGETDRLIRKCVLLPWVPNEVLDVNCFTPEPSDEHYQAILAENKEKLPIAINPSVYDKDKVFKVFTDIQQVLNSLTHPRFVFTDKEAEADILYNFSHFKDYRKLSEERPEVMLNQFPCENLLTVKDCLASISRRAGGPDGPRWLPRTFNLQTELPQFICYFQQRERRGEDNHWICKPWNLARSLDTHITNSLNNIIRHRESSPKVVCKYIENPVLFHREDVGMVKFDIRYVVLLRSVKPLKLYVYDVFWLRFSNRAFSLDDLDDYEKHFTVMNYAPGVTLKQVHCEEFVPQFEKQYPEHLWTTVQANIFKAFAELFQVASAKPAPLGICDYPSSRAIYAIDLMLKWDTSRDGKRIMQPQILEVNFNPDCDRACKYHPTFFNDVFSTLFLDEADNCHVTCIV", "length": 626, "header": "tr|A0A8V0YBT4-1|A0A8V0YBT4_CHICK Isoform 1 of Tubulin tyrosine ligase like 12 OS=Gallus gallus OX=9031 GN=TTLL12 PE=1 SV=1 CANONICAL=A0A8V0YBT4-1" }, "locus": { "chromosome": "1", "start_pos": 68631104, "end_pos": 68615689, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028586.1", "url": "https://www.ensembl.org/id/ENSGALT00010028586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016417.1", "url": "https://www.ensembl.org/id/ENSGALP00010016417.1" } ] } }, { "isoform_ac": "A0A8V0YBT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4/entry#A0A8V0YBT9-1", "sequence": { "sequence": "MSGDGDEELAAFVALHGAALRASCVPARYWESLCRKLRGEVFDAGDYFGIMQVEEVDEEEEGDEAMEDELKKKPNPGNEPCFKVIVTNENGLQASNPDSIFLIDHAWTYRIEHARQQLLHVPGLLHRMANLMGIDFHGEIPDEGSVEQVLQEMWKYNQTYQLSQGTAEEKVPVWYIMDEFGSRIQHSDQPSFATAPLFYMPQQIAYTVLWPLRDLETGDEVTRDYAYGETDRLIRKCVLLPWVPNEVLDVNCFTPEPSDEHYQAILAENKEKLPIAINPSVYDKDKVFKVFTDIQQVLNSLTHPRFVFTDKEAEADILYNFSHFKDYRKLSEERPEVMLNQFPCENLLTVKDCLASISRRAGGPDGPRWLPRTFNLQTELPQFICYFQQRERRGEDNHWICKPWNLARSLDTHITNSLNNIIRHRESSPKVVCKYIENPVLFHREDVGMVKFDIRYVVLLRSVKPLKLYVYDVFWLRFSNRAFSLDDLDDYEKHFTVMNYAPGVTLKQVHCEEFVPQFEKQYPEHLWTTVQANIFKAFAELFQVASAKPAPLGICDYPSSRAIYAIDLMLKWDTSRDGERSSFICTLNSYL", "length": 591, "header": "tr|A0A8V0YBT9-1|A0A8V0YBT9_CHICK Computationally mapped isoform of Tubulin tyrosine ligase like 12 OS=Gallus gallus OX=9031 GN=TTLL12 PE=1 SV=1 CANONICAL=A0A8V0YBT4-1" }, "locus": { "chromosome": "1", "start_pos": 68635060, "end_pos": 68616725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028594.1", "url": "https://www.ensembl.org/id/ENSGALT00010028594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016422.1", "url": "https://www.ensembl.org/id/ENSGALP00010016422.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ], "pmid": "" }, { "name": "negative regulation of type I interferon-mediated signaling pathway", "id": "GO:0060339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone H4K20me2 reader activity", "id": "GO:0140005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YBT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YBT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBT4" }, { "id": "PF25556", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25556" } ], 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"table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YC02-1", "uniprot_ac": "A0A8V0YC02", "uniprot_id": "A0A8V0YC02_CHICK", "mass": { "chemical_mass": 46949.0, "monoisotopic_mass": 46949.0 }, "refseq": { "ac": "XP_040518947", "name": "protein NDRG1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518947" }, "gene_names": [ { "name": "NDRG1", "type": "recommended", "evidence": [ { "id": "A0A8V0YC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ] }, { "name": "NDRG1", "type": "synonym", "evidence": [ { "id": "XP_040518947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518947" } ] } ], "protein_names": [ { "name": "N-myc downstream regulated 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02/entry#names_and_taxonomy" } ] }, { "name": "protein NDRG1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040518947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518947" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040518947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518947" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02", "locus": { "chromosome": "2", "start_pos": 140960629, "end_pos": 140990419, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009749", "url": "https://www.ensembl.org/id/ENSGALG00010009749" } ] } } ], "crossref": [ { "id": "A0A8V0YC02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YC02", "database": "AlphaFoldDB", "categories": [] }, { "id": "420321", "url": "https://www.ncbi.nlm.nih.gov/gene/420321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LVEKGEX", "url": "https://omabrowser.org/oma/group/LVEKGEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC02", "url": "https://www.orthodb.org/?gene=A0A8V0YC02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040518947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518947", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLDIPVHVFSIIKFEARYQLLTMSTEFQDAHLAEVKPLVEKEEAITRLLPDFDVQEQDVETMHGMVHVTMCGTPRGNRPAILTYHDIGLNHKTCFNPLFNFEDMQEITQHFAVCHVDAPGQQDGAPSFQAGYIYPSMDQLAEMLPGILKQFGLKSIIGMGTGAGAYVLTRFALNHPDMVEGLVLININPCAEGWMDWAATKISGWTNALPDLVISHLFGKEEIHSNHDLIHTYRQHIINDMNQTNLHLFVNSYNSRRDLEIERPVPGLNVVTLQCPVLLVVGDSSPAVDAVVECNSKLDPTRTTLLKMADCGGLPQVSQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLEGQRSRSHTGEGTRSRSHTGEGTRSRSHTGEGSRNRSHTDTRIELTPNSASNAEQSGPKSMEVSC", "length": 425, "header": "tr|A0A8V0YC02-1|A0A8V0YC02_CHICK Isoform 1 of N-myc downstream regulated 1 OS=Gallus gallus OX=9031 GN=NDRG1 PE=1 SV=1 CANONICAL=A0A8V0YC02-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02/entry#A0A8V0YC02-1", "sequence": { "sequence": "MNLDIPVHVFSIIKFEARYQLLTMSTEFQDAHLAEVKPLVEKEEAITRLLPDFDVQEQDVETMHGMVHVTMCGTPRGNRPAILTYHDIGLNHKTCFNPLFNFEDMQEITQHFAVCHVDAPGQQDGAPSFQAGYIYPSMDQLAEMLPGILKQFGLKSIIGMGTGAGAYVLTRFALNHPDMVEGLVLININPCAEGWMDWAATKISGWTNALPDLVISHLFGKEEIHSNHDLIHTYRQHIINDMNQTNLHLFVNSYNSRRDLEIERPVPGLNVVTLQCPVLLVVGDSSPAVDAVVECNSKLDPTRTTLLKMADCGGLPQVSQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLEGQRSRSHTGEGTRSRSHTGEGTRSRSHTGEGSRNRSHTDTRIELTPNSASNAEQSGPKSMEVSC", "length": 425, "header": "tr|A0A8V0YC02-1|A0A8V0YC02_CHICK Isoform 1 of N-myc downstream regulated 1 OS=Gallus gallus OX=9031 GN=NDRG1 PE=1 SV=1 CANONICAL=A0A8V0YC02-1" }, "locus": { "chromosome": "2", "start_pos": 140990263, "end_pos": 140962199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023292.1", "url": "https://www.ensembl.org/id/ENSGALT00010023292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013470.1", "url": "https://www.ensembl.org/id/ENSGALP00010013470.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M9W0-1", "protein_name": "N-myc downstream regulated 1", "gene_name": "NDRG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRELQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSIHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAASFPTGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEMQNNVEVVHAYRHHVMNDMNPGNLQLFINAYNSRRDLEIERPMPGAHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLEGARSRSHTSEGTRSRSHTSEGTRLDIIPNSGGPGSSAGPNSTEVSC", "length": 384 }, "evidence": [ { "id": "A0A8V0YC02", "url": "https://omabrowser.org/oma/group/A0A8V0YC02/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q62433-1", "protein_name": "Protein NDRG1", "gene_name": "Ndrg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRELHDVDLAEVKPLVEKGESITGLLQEFDVQEQDIETLHGSLHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAPSFPVGYMYPSMDQLAEMLPGVLHQFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVLMNVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEIHNNVEVVHTYRQHILNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLEGTRSRSHTSEGPRSRSHTSEGSRSRSHTSEDARLNITPNSGATGNNAGPKSMEVSC", "length": 394 }, "evidence": [ { "id": "A0A8V0YC02", "url": "https://omabrowser.org/oma/group/A0A8V0YC02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6JE36-1", "protein_name": "Protein NDRG1", "gene_name": "Ndrg1", "tax_id": 10116, "organism": "Rattus 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"MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC", "length": 394 }, "evidence": [ { "id": "A0A8V0YC02", "url": "https://omabrowser.org/oma/group/A0A8V0YC02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FJT7-1", "protein_name": "Protein NDL1", "gene_name": "NDL1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTDSYGAVSVDVGTIYLGGKEHRVKTASGVVSVIVYGDREKPALITYPDLALNHMSCFQGLFFCPEAASLLLHNFCIYHISPPGHELGAAPICPNDSVPSAENLADQILEVLNFFGLGVVMCMGVTAGAYILTLFAMKHRERVLGLILVSPLCKAPSWSEWFYNKVITNLLYYYGMCGVVKEFLLQRYFSKEVRGNVEIPESDIAQACRRLLDERQGINVLRFLDAIDRRPDISSGLKKLKCRTLIFIGDQSPFYSEAVHMAATLDRGYCALVEVQACGSMVTEEQPHAMLIPMEYFLMGYGLYRPSLFSESPRSPLSPSCISPELLSPESMGLKLKPIKTRISAA", "length": 346 }, "evidence": [ { "id": "A0A8V0YC02", "url": "https://omabrowser.org/oma/group/A0A8V0YC02/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "peripheral nervous system myelin maintenance", "id": "GO:0032287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC02" } ], "pmid": "" }, { "name": "DNA damage response, signal transduction by p53 class mediator", "id": 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"CAAGWGCWPRSVLLWLVCVCVCESGAETLRYSVAEEMARDSLVGNVAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPVFPQKEMVLDISETASPGSRFSLESAQDEDVGINGLQNYSLSPNSHFSLALETGKGGTKYVKLVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSYGKVRYSFSQISQGSRQFFTLDTETGEIRISGNLDYEEAQYHEIEVKAMDGGGLSAHCKVHVEVLDVNDNAPEMALSSVSASIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEGEERPAVSVDAESGAVSVVRPLDYEEVRAVEVTVRAADGGSPPRSATALLRVLVRDENDNAPVVLHPPADGGAALGELVPRRARAGYLVAKVVAVDADAGQNAWLCYELAKATEPGLFRVGLHSGEVRTARAVGERDAARHRLVVLVRDRGRPPRSASATLAVALADGFSEGHLRASEEAPAAEPDGRLTLYLSVCLACVSALFVAGAAAAVAAKVRRARRGEPGTLPTFPQSAADSSAGSLPRSYVYDVRLAAGTVNSEFRFLGPLLPCFPAGLPQGAAEQRSSLCSAFNVLLALVFDSG", "length": 794, "header": "tr|A0A8V0YC21-1|A0A8V0YC21_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YC21-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC21/entry#A0A8V0YC21-1", "sequence": { "sequence": "CAAGWGCWPRSVLLWLVCVCVCESGAETLRYSVAEEMARDSLVGNVAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQLIRGEVEVRDVNDHSPVFPQKEMVLDISETASPGSRFSLESAQDEDVGINGLQNYSLSPNSHFSLALETGKGGTKYVKLVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSYGKVRYSFSQISQGSRQFFTLDTETGEIRISGNLDYEEAQYHEIEVKAMDGGGLSAHCKVHVEVLDVNDNAPEMALSSVSASIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEGEERPAVSVDAESGAVSVVRPLDYEEVRAVEVTVRAADGGSPPRSATALLRVLVRDENDNAPVVLHPPADGGAALGELVPRRARAGYLVAKVVAVDADAGQNAWLCYELAKATEPGLFRVGLHSGEVRTARAVGERDAARHRLVVLVRDRGRPPRSASATLAVALADGFSEGHLRASEEAPAAEPDGRLTLYLSVCLACVSALFVAGAAAAVAAKVRRARRGEPGTLPTFPQSAADSSAGSLPRSYVYDVRLAAGTVNSEFRFLGPLLPCFPAGLPQGAAEQRSSLCSAFNVLLALVFDSG", "length": 794, "header": "tr|A0A8V0YC21-1|A0A8V0YC21_CHICK Isoform 1 of Cadherin domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YC21-1" }, "locus": { "chromosome": "13", "start_pos": 1240090, "end_pos": 1236740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026636.1", "url": "https://www.ensembl.org/id/ENSGALT00010026636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015189.1", "url": "https://www.ensembl.org/id/ENSGALP00010015189.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC21" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YC21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC21" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 131, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 417, "end_pos": 419 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YC22-1", "uniprot_ac": "A0A8V0YC22", "uniprot_id": "A0A8V0YC22_CHICK", "mass": { "chemical_mass": 319545.0, "monoisotopic_mass": 319545.0 }, "refseq": { "ac": "XP_004937716", "name": "small subunit processome component 20 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937716" }, "gene_names": [ { "name": "UTP20", "type": "recommended", "evidence": [ { "id": "A0A8V0YC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" } ] }, { "name": "UTP20", "type": "synonym", "evidence": [ { "id": "XP_004937716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937716" } ] } ], "protein_names": [ { "name": "UTP20 small subunit processome component", "type": "synonym", "evidence": [ { "id": "A0A8V0YC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22/entry#names_and_taxonomy" } ] }, { "name": "small subunit processome component 20 homolog", "type": "synonym", "evidence": [ { "id": "XP_004937716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937716" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004937716.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937716" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UTP20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22", "locus": { "chromosome": "1", "start_pos": 47749831, "end_pos": 47689981, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011663", "url": "https://www.ensembl.org/id/ENSGALG00010011663" } ] } } ], "crossref": [ { "id": "417933", "url": "https://www.ncbi.nlm.nih.gov/gene/417933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417933", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417933", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EGLMAMF", "url": "https://omabrowser.org/oma/group/EGLMAMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC22", "url": "https://www.orthodb.org/?gene=A0A8V0YC22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17695:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17695:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07539", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07539", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004937716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGKSSAHKSGNTHRFLTFSERLSNVNIDIIHRIDRTGSSAEEVETYFYEGLQKWRELNLTQHFVQFYKEVANKCQSFNQLVYYQSAIVQSLKTHLQVKASLAYQPLLDLVVQLARDLQADFYPHFHDFFVAITKLLDTQDTELLEWAFTSLSYLYKYLWRLMVKDISNIYSLYSTLLAHHKLHIRNFAAESFVFLMRKVSDKNALFNLMFRDLGEHPKKVEGVGRLLFEMCKGVRNMFHSCTETALKLILVKLGPVTEEETELPWITIGEAFEQMIRSAAVHIHREHFDIVFKCLKESLLNLQSKITKVNCCMASEQMERVLRAYLILVEHANGSKISQPEEVCQVLIKMLQTPDLLPSCCKILLNTISALLLAENVLLPDSLTKEAIEKVFGSGIEWCFLLDFSEAMFTMKQFERHFLPCFLKYVEHCFSGTDVLRKDQATAILAKLILVKAEPPTIGSMAFEKYPLLFTESSSISSNTRQQTSKRQGGRAEVPVLDHVLSLIQLPENEDITDLSQPWVALVVLPHIRPMDKEMILPCVTSFIDSLFTAIDKGSLCKGSLFVACQAVSTLLGLTESSEILHLLPVERVKNLVTTFPSDPSALLLADLYYTRLALCGCQEPLSQGNLMDLFEKLQPNISTGISKVRLLTVRILNHFETPPSTVIEGDGTGELQSVFATLLQAELVPATVNDYREKLLHLRKLRCDIVLSAVPSGSLQEVPLRYLLGMLYINFSPLWDPVIELITSHAKEMENKQFWKVFYEHLERAAAYAEMELQNELDEQEESIDENESQKIPEGGVGTVFLEQLGTRTDCSERLDHTNFRFLLWKALEKFPDRVEPRSRELSPLLLRFIRNEYYPADSLVAPTQDLRKKTTGTVTAKEVSGEEVNDVNMEEEGEEEREEGEPITVGLPKKKTRRAAAKQLIAHLQVFSKFSNPRALYLEQKLNALYTQLLSHQDQNVQRIALDCIMTYKHPHLLPYRENLQRLLEDKSFKEEIVHFSISEENTIVKVEHRPHLVPVLMRILYGRMRNKTGNKTQGKSAAATRMSIVLRFLAGSLPEEIRMFLDLLFEAVKQFSHGPCQAAVLRSVSELDLAKVLPLGRQHSLFNGLEVVLKNMGHLISQYLPEILQILLCMTAVVSCILQQREKVQPRLINPLKNLRRFGLKLVVEFFSDHETYSFSVEEIDAVFHAVVWPQVCRLASESQYSPTFLLKLIYTWSKNPRYFPLLAKQYPDRPEYDILSNVFAVLSAKNLSEATSSLVMDIADSLLNSPNFEPTEQVSSLNVTDCVVLNTGEVTEETLSLGCRLVLPHVPAILQYFSKTMLNVEKMKKKKYRAQVSKELSILSKISKFIQEKSQNSVLVSLLLPFLHQSNIEQDAEIDILETVQNLLRHCSNPASFLKPLAKLFSVIQNKLSRQKLCLVFQTLSDLDSDLKYITDVVKLNAFDQRHLDDINFDVRLSAFQSITAHIKEMQTVDINFLIPVMHNCFYTIQLGDMALSDNASLCLTSFIHRLAEIDHTEEDYKELIQHTLLESLRRGLKSKTESIQQDYTSLLSCLIQTFPANPEFRDLVQLTNCHDPDMDFFENMKHMQIHRRARALRRLAKQLTEKKLVLSSKSLQNYIMPYATTAIFSEKMLKHENMVTASVEVVGAICRHLSWSAYLYHLKHFIHVLQTGQISPKLGVSLLETVLEAFHFDHETLEKQLVTIENQEAAAMDLEPEVEGEEGMELEQSEAEEEVVEEDKRENIREETAEPELVLPEKAAETPENTEQVAKPVSFLPRNKEELECLIKHIQDTVIVNILPKLHRCIVAKVKRDEEHKLVKSSVVNDDEVVRVPLAFAMVRVMQCLPQEVMEANLPSILLKVCSFLRNRFQEIRDVARNTLTKIMEVLGVQYLLYVLKEMQSTLIHGYQLHVLTFTVNLLLKGLTTRLSAGDLDPCLDILIEIFNQELFGDVAEEKEVKGIVSKVMEARKNKSYDSYEILGKYIGKGQVTKLILPLKEILETTTSLKIVRKVHEALRHIMAGLIFNSDMNAESLLLLSHGLISENLPLLTEKAKTKAAPPPDPRLQPESCLLLQPTPTRGGQKAPVSRRTNTYILVESGLRLLHMSLKRSKVNSSDEHVLEMLDPFVQLLIDCLKSMDVKVITGALQSLVWILKFPLPSINTNLESLIKQLFLLLKEFAKTGVAKGQNFHLVVNCFKSVTILVKNAKSQITSKQLQVLLGFAEEDIYDSSRQATAFGLLKAILSRKLIVPEIDDVMQKVAQLAITGQSEPVRVQCRQIYLKYILDYPLGDKLKPNLDFMLAQLDYEYETGRESALEMIVYLLDMFPQELLHKYCGLFFISLCMMMINDDSAKCKKMAALTCKSLLSKINNDKQDLLFSLVTEWFHSKKSSHRRLAAQACGLFVEVEGVMFERRLEAVLTLVEKEINPVQFEDITEEEEEKAADRLLFSFLVLVTKLISECSLIQLTKHADTVSQIWDHVQSHLWHPHSWVWLTATQIFGLLFASHKPEDLVAKWRERQAVKRKKPSAELSASTFFLTAELDRKVKELVFAFCHQLHSKFLDQSLGEQVIKNLLFVAKVIYLLAPPSEEGEQAEGELGCEVEEQEASEDEEEKDVSAQGEGEGEDTEEKGRPATLIWLMKKLSLMAKREAAYSPKIPLKRSCIFKFLGAISVDLGKDRIRPYLPTVLTPLYRELNSTYAEQDPTLKNLSQEIIELLKKLVGLEAFSLAFSSVQKQANQKRAMRKKQRALQAVANPDIAARRKLKRHKNKAETRKRKIEFLRPSYKAKKHRSHALKDLAMVE", "length": 2801, "header": "tr|A0A8V0YC22-1|A0A8V0YC22_CHICK Isoform 1 of UTP20 small subunit processome component OS=Gallus gallus OX=9031 GN=UTP20 PE=1 SV=1 CANONICAL=A0A8V0YC22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22/entry#A0A8V0YC22-1", "sequence": { "sequence": "MKGKSSAHKSGNTHRFLTFSERLSNVNIDIIHRIDRTGSSAEEVETYFYEGLQKWRELNLTQHFVQFYKEVANKCQSFNQLVYYQSAIVQSLKTHLQVKASLAYQPLLDLVVQLARDLQADFYPHFHDFFVAITKLLDTQDTELLEWAFTSLSYLYKYLWRLMVKDISNIYSLYSTLLAHHKLHIRNFAAESFVFLMRKVSDKNALFNLMFRDLGEHPKKVEGVGRLLFEMCKGVRNMFHSCTETALKLILVKLGPVTEEETELPWITIGEAFEQMIRSAAVHIHREHFDIVFKCLKESLLNLQSKITKVNCCMASEQMERVLRAYLILVEHANGSKISQPEEVCQVLIKMLQTPDLLPSCCKILLNTISALLLAENVLLPDSLTKEAIEKVFGSGIEWCFLLDFSEAMFTMKQFERHFLPCFLKYVEHCFSGTDVLRKDQATAILAKLILVKAEPPTIGSMAFEKYPLLFTESSSISSNTRQQTSKRQGGRAEVPVLDHVLSLIQLPENEDITDLSQPWVALVVLPHIRPMDKEMILPCVTSFIDSLFTAIDKGSLCKGSLFVACQAVSTLLGLTESSEILHLLPVERVKNLVTTFPSDPSALLLADLYYTRLALCGCQEPLSQGNLMDLFEKLQPNISTGISKVRLLTVRILNHFETPPSTVIEGDGTGELQSVFATLLQAELVPATVNDYREKLLHLRKLRCDIVLSAVPSGSLQEVPLRYLLGMLYINFSPLWDPVIELITSHAKEMENKQFWKVFYEHLERAAAYAEMELQNELDEQEESIDENESQKIPEGGVGTVFLEQLGTRTDCSERLDHTNFRFLLWKALEKFPDRVEPRSRELSPLLLRFIRNEYYPADSLVAPTQDLRKKTTGTVTAKEVSGEEVNDVNMEEEGEEEREEGEPITVGLPKKKTRRAAAKQLIAHLQVFSKFSNPRALYLEQKLNALYTQLLSHQDQNVQRIALDCIMTYKHPHLLPYRENLQRLLEDKSFKEEIVHFSISEENTIVKVEHRPHLVPVLMRILYGRMRNKTGNKTQGKSAAATRMSIVLRFLAGSLPEEIRMFLDLLFEAVKQFSHGPCQAAVLRSVSELDLAKVLPLGRQHSLFNGLEVVLKNMGHLISQYLPEILQILLCMTAVVSCILQQREKVQPRLINPLKNLRRFGLKLVVEFFSDHETYSFSVEEIDAVFHAVVWPQVCRLASESQYSPTFLLKLIYTWSKNPRYFPLLAKQYPDRPEYDILSNVFAVLSAKNLSEATSSLVMDIADSLLNSPNFEPTEQVSSLNVTDCVVLNTGEVTEETLSLGCRLVLPHVPAILQYFSKTMLNVEKMKKKKYRAQVSKELSILSKISKFIQEKSQNSVLVSLLLPFLHQSNIEQDAEIDILETVQNLLRHCSNPASFLKPLAKLFSVIQNKLSRQKLCLVFQTLSDLDSDLKYITDVVKLNAFDQRHLDDINFDVRLSAFQSITAHIKEMQTVDINFLIPVMHNCFYTIQLGDMALSDNASLCLTSFIHRLAEIDHTEEDYKELIQHTLLESLRRGLKSKTESIQQDYTSLLSCLIQTFPANPEFRDLVQLTNCHDPDMDFFENMKHMQIHRRARALRRLAKQLTEKKLVLSSKSLQNYIMPYATTAIFSEKMLKHENMVTASVEVVGAICRHLSWSAYLYHLKHFIHVLQTGQISPKLGVSLLETVLEAFHFDHETLEKQLVTIENQEAAAMDLEPEVEGEEGMELEQSEAEEEVVEEDKRENIREETAEPELVLPEKAAETPENTEQVAKPVSFLPRNKEELECLIKHIQDTVIVNILPKLHRCIVAKVKRDEEHKLVKSSVVNDDEVVRVPLAFAMVRVMQCLPQEVMEANLPSILLKVCSFLRNRFQEIRDVARNTLTKIMEVLGVQYLLYVLKEMQSTLIHGYQLHVLTFTVNLLLKGLTTRLSAGDLDPCLDILIEIFNQELFGDVAEEKEVKGIVSKVMEARKNKSYDSYEILGKYIGKGQVTKLILPLKEILETTTSLKIVRKVHEALRHIMAGLIFNSDMNAESLLLLSHGLISENLPLLTEKAKTKAAPPPDPRLQPESCLLLQPTPTRGGQKAPVSRRTNTYILVESGLRLLHMSLKRSKVNSSDEHVLEMLDPFVQLLIDCLKSMDVKVITGALQSLVWILKFPLPSINTNLESLIKQLFLLLKEFAKTGVAKGQNFHLVVNCFKSVTILVKNAKSQITSKQLQVLLGFAEEDIYDSSRQATAFGLLKAILSRKLIVPEIDDVMQKVAQLAITGQSEPVRVQCRQIYLKYILDYPLGDKLKPNLDFMLAQLDYEYETGRESALEMIVYLLDMFPQELLHKYCGLFFISLCMMMINDDSAKCKKMAALTCKSLLSKINNDKQDLLFSLVTEWFHSKKSSHRRLAAQACGLFVEVEGVMFERRLEAVLTLVEKEINPVQFEDITEEEEEKAADRLLFSFLVLVTKLISECSLIQLTKHADTVSQIWDHVQSHLWHPHSWVWLTATQIFGLLFASHKPEDLVAKWRERQAVKRKKPSAELSASTFFLTAELDRKVKELVFAFCHQLHSKFLDQSLGEQVIKNLLFVAKVIYLLAPPSEEGEQAEGELGCEVEEQEASEDEEEKDVSAQGEGEGEDTEEKGRPATLIWLMKKLSLMAKREAAYSPKIPLKRSCIFKFLGAISVDLGKDRIRPYLPTVLTPLYRELNSTYAEQDPTLKNLSQEIIELLKKLVGLEAFSLAFSSVQKQANQKRAMRKKQRALQAVANPDIAARRKLKRHKNKAETRKRKIEFLRPSYKAKKHRSHALKDLAMVE", "length": 2801, "header": "tr|A0A8V0YC22-1|A0A8V0YC22_CHICK Isoform 1 of UTP20 small subunit processome component OS=Gallus gallus OX=9031 GN=UTP20 PE=1 SV=1 CANONICAL=A0A8V0YC22-1" }, "locus": { "chromosome": "1", "start_pos": 47749659, "end_pos": 47690065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027911.1", "url": "https://www.ensembl.org/id/ENSGALT00010027911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016014.1", "url": "https://www.ensembl.org/id/ENSGALP00010016014.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417933", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417933", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1P8B4E4-1", "protein_name": "ARM repeat superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATSADARAVKSLNTSEGRKRFVFKSASQRTNDIDNISNYRNLDKVKAEPSEGSTFFRDCLIEWRELNTAEDFILFYEEMLPSVQSLSLIIMQKERIFSNLVSRLQMKARLSLEPILRLIAALSRDLLNDFIPFLPQIVNSFVTLLNNGAHNDPEIIQQVFTSWASIIVSLQKYLVCDIEGILRDTLELRYYPKDNISEFMSESMSFLLRKAQDEQLEKGMKMILSEVAHPSKKAGGVGVLYNVMRGTYGRLHSKAGRVLSFLLKDSTLSFLDNFPQGPCTVVEVVSLVLQRICEDLEAEKLSAMWEYLYKKINKSISNKKSVHLSRLLSVLMAVVKIKEGRKVHDIPSLIGIVSRIVSTFFTSSETAVEGDNLSAVLDEVLELILCTINTVNEMETVASLWAPIFALKSSSLLTFLREFLKKDQSVVKAFTKNILCAINNMIWESSEEVIPLLLTLCEEHKTQQTSHDVVNSISQTFESRYERIHEFLEAKIKKVQQNIENAGLAQINEAELAAIWGVVKCYPYFKVDSSLLICFKKTLRQHLAVSDVDTCSGPELMWQSLLGTTLRSCYKMTGINHSDLEEALSFAKDYKSCEQVLSPVADVLEFMHRPALAHGRSKPYPELQANKAGDAFEIFSENLRHPNKNIRLMTLRILCHFETLSSDPSFEEHPPKKKMKTEKNVLQLLLLFEETAPTVDTSRMLAGYISTIQDNLSAGRIHSAYVKLVLNGMLGILHISYRPLCVQASECLAVLVRKYTGAVWSDFVCYLGQCQLKFETLHDHSENANQSMSERHACNLNLNGRFNLFLFPPSAITPTATVSDVVSQLLQTLQKASSVAQSRASEILPLLLKFLGYNSENPGSVGSYNGRVCKGEDWKTVLVQWLTLLKLMKNPRSFCFSQFLNDILQNRFLDDNDAEIQTNVLECLLLANDFLLPHRQHLLNLIKPKELREELTTWNLSENIGEPHRSYIFSLVIRILMPKVRTLKNSASRKHTSIRHRKAVLCFISQLDVNELALFFALLIKPLNIISEETMDSFWSSGKSSLDYFQNSNFLKYFTVDTISTLSRNQKFGFLHVIQHILEVFDELRVRPFLDFMMGCVVRLLVNYAPNVDEEMNIDSLALRNVTAAPSTSDDKENASINHDQAGTAFKQFKELRSLCLKIIAHVLDKYEDCDLGSEFWDLFFSAVSPLIKSFKQEGSSSEKPSSLFSCFLSMSKSRNLVNLLCREESLVPDIFSILTVTTASEAIKSSALKFIENLLCLDNVLGEDENMIRGFVDPYIEALINSLHSLFIGDILKRKSVKYHGEREIKILKLLSKRMQDRSHVMKYLDVLLSFLNKSVKDPDIRREALLAIQDIIAYLGMESTSKIINTVSPLLVDAELDVRLCICDLLESLAKIDFSLDDVAKRVRDMNAISAMEVDDLDYEKIVNAYVEINADFFIKSSEQHTMIILSQSSILCREAPAHSEFGKEVKNADVSWTGDRVLCILRNFILKHIGDAINRGGIIIKEWILLIREMVTKLPDAANLSAFRPLCSEDENVDFFKAIVHIQAHRRARAISRFSSVVKDSSLPEGVVRKLLVSVFFNMLLEGQDGKDNNVRNACTEALASISAHMSWTSYYALLNRCFREMNKHTKKGKILLRLICLILDKFHFAKDGYPHEAEEIRTCLQKIVFPRMQKLMNSDSDNVNVNSSVAALKVLKLLPEDVLDSNLSSIVHKIASFLKNRLESTRDEARLALVACLKELGLEYLQVVVNILRAILKRGSEVHVLGYTLNSILSKCLSNPTCGKLDHCLVDLLAVVETDILGEVAEQKEVEKFASKMKETRKRKSFETLKLIAENVTFRSHGLKLLSPVTAQLQRHLTPKIKTNLEKMLKQIAAGIEGNTSVDQGDLFLFIYGLVDDGINNRSGLGDQVSLPPSKKKKKSRDLKETSGLCFGPKSCPHLITVFALDLFYNRMKKLRLDNTDEELLSKLDPFVKLLAGCLSSKYEDIVSSSLRCFTSLVKFPLPSLTSEADELKTALLTIAQSAVSSSSPLVQSCLKLLTTLLKNINITLSSEQLKMLIQFPIFIDLESDSSFVTLSLLKAIMNRKLVVPEIYDIAIQVSKLMVNSQLESIRKKCKHILLQFMVHYTLSEKRLEQHVNFLLENLRYEFPTGREAVLDMLHALILKFSEPNLGKQSVLDQQSQKLFIQLTVCLSNETDRKVLPLVGAVIEVLIGRMSKDQVDSSLLYCLCWYKQQNLSAAAAQVLGFFISAMKKTFRKHIYNTVEDARTILESAISASSLQLQDTVEEASLPFWKEAYYSLVMIEKMLEQFPDLRFGKDLEDIWKMVFKFLLHPHAWLRNKSCRLLNLYFEALAGRKRPECRTLVADSLLEKPSSLFMVAVSLCFQLKEQPTTGNIDVDLLTANIVFAVSSLHSLIGQFDQATHNRFWSSLGEDEQVVFLKAFEVLDAGKGRSTFLALTSGKRTENGDDDVRNVMIGSLLKRMGKIALDMESVQMRVMFNVYKSFASQLNQEECRLYAYKILLPLYKVCEGYTGKIVTDELKQLAEEVRDSIRDKSLGNKMFVEVYSEIRNSLRTKRDKRKREEKLMAVVNPERNAKRKLRLASKNKANKKRRMTSMKLSRWACS", "length": 2624 }, "evidence": [ { "id": "A0A8V0YC22", "url": "https://omabrowser.org/oma/group/A0A8V0YC22/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F1LXT3-1", "protein_name": "UTP20 small subunit processome component", "gene_name": "Utp20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPKPVSHKTENTYRFLTFAERLGNVNIDIIHRIDRTASYDEDVETYFFEALLKWRELNLTEHFGKFYKEVIDKCQSFNQLVYHQNEIVQSLKTHLQIRNSFAYQPLLDLVVQLARDLQTDFYPHFEDFFLTITSILETQDTELLEWAFTSLSYLYKYLWRLMVKDISKIYSLYSTLLAHKKLHIRNFAAESFTFLMRKVSDKNALFNLMFLDLNEHPEKVEGVGQLLFEMCKGVRNMFHSCTGQALKLILQKLGPVTETETQLPWILVGETLKNMAKSTVVYIHKEHLGVFFDCLQESLLELHNKVTKANCSENSDQMRRLLETFLIVVKHGSGSKVAQPADICGVLLEALQTAHLSTSCRKTLLDVVSALLLVENVSLPEALIEETIEKVFESKFERRLILDFSEVMFAMKQFEQLFLPSFLLYIENCFLMDDSVASDEALAILAKLILNKAAPPTAGSMAIERYPLVFSQQTVGSYLKQRKAESKRRKGQFPVLDHLSSIVQSPPNNDAASLSQSWAALVVLPHLRPLDKEKTISLVSCFIESLFLAVDRGSFGKGNLFVLCQAVNTLLSLEESSELLHLVPVERVKHLVLTFPAEPSVLLLADVYYQRLALCGCKGPLSEEALMELFPKLQANISTGVSKIRLLTIRILNHFDIQLPVSMEDDGLSEQQSAFAILRQAELVPATVSDYREKLLHLRKLRHDVVQSAVPQGPLQEVPLRYLLGMLYINFSALWDPVIELISSHAHGMENKQFWNVCYEHLEKAASHAEKELQKDTRDEESEGGGSWEQTQEGDVGTLYQQQLALKTDCRERLDHTNFRFLLWKALAKFPERVEPRSRELSPLFLRFINNEYYPADLQVAPTQDLRRKGRGAVSEEVEEEPAAGEGEDVEEEAAPTDEAPQKKKTRRAAAKQLIAHLQVFSKFSNPRALYLESKLYELYLQLLLHQDQAVQKITLDCIMTYRHPHILPYRENLQRLLDDRSFKEEIVHFNISEDNSVVKAAHRADLFPILMRILYGRMKHKTGSKTQGKSASGTRMSIVLRFLAGTQPEEIQFFLDLLSEPVKHFKDGDCCSAVIRAVEDLDVSKVLPVGRQHGVLNSLEIVLKNISHLISTYLPKILQILLCMTAAISHILDQREKIQLRFINPLKNLRRLGIKMVTDIFLDWESYQFSAEEIDAVFHGTVWPQICRLGSESQYSPTPLLKLISIWSRNARYFPLLAKQKPGHPECDILTNVFAVLSAKNLSGATASIIMDIVDDLLNLPDFEPTEAVPSLPVTGCVYANVAENTGAYLTVSEPVTVGGRLILPHVPAILQYLSKNTISAEKVKKKKNRAQVSKELGILSKISKFMKDREQCSLLITLLLPFLLRGNVPQDTELDILVTVQNLLQHCLDPSHFLRPLAKLFSVIKNKLSRQLLCTVFQSLSDCESGLKYITDIVKLNAFDKRHLDDINFDVRFSAFQTITSHIKAMQTVDVDYLVAVMHNCFYNMEIGDMSLSDNASICLTSIIKRLAALNVTEKEYKEIIHRTLLEKLRKGLKSQTESVQHDYTLILSCLIQTFPNQLEFKDLVQLTHYHDPEMDFFENMKHIQIHRRARALKKLANQLLEGQVMLSSKSLQNYIMPYAMAPILDEKMLKHENITIAATEVIGAICRHLTWPAYVYYLKHFIHVLQSGQINQKLAVSLLVIVLEAFHFDYKTLEEQMGNVKNEENTVEMTELLEHEAMEVEDMDEQEKEQASERLSDSKEPSGAPEAAASEGTAAKEPECISKSVSFLPRNKEELERTIKTIQGAITGDILPRLHKCLAAATKREEEHKLVKSKVVNDEEVVRVPLAFAMVKLMRSLPREVMEANLPSILLKVCVLLKNRAQEIRDIARSTLCKIMEDLGVHFLQYILKELQTTLVRGYQVHVLTFTVYTLLQGLSSKLHVGELDSCLQIMTEIFNHELFGALAEEKEVKQILSKVMEARRSKSYDSYEILGKFVGKQQVTKLILPLKEILQNTTSLKLARKVHETLRRIIAGLIVNPDMTADALLLLSYGLVSENLPLLTEKEKKPAAPVPDARLPPQSCLLLPATPVRGGAKAVVSKKTNMHVFIESGLRLLHLSLKTSKIKSSSERVLEMLDPFVSVLINCLGAQDVKVITGALQCLIWVLRFPLPSIATKADQLTKHLFLLLKNYARLGAARGQNFHLVVNCFKCVTIVVKKVKSHQITEKQLQVLLAYAEEDIYDTSRQATAFGLLKAILSRKLLVPEIDDVMRKVSKLAISAQSEPARVQCRQVFLKYILDYPLGEKLRPNLEFMLAQLSYEHETGRESTLEMIAYLFETFPQGLLHDYCGMFFIPLCLMMINDDSAMCKRMASMAVKSLLSKVSREKKDWLFALVTSWFEAKKRLNRQLAALACGLFVESEGVDFERRLGTLLPVIEKEIDPESFKDIIEETEEKAADRLLFGFLTLISKLIKECNILHFTKPSETLSKIWSHVHSHLRHPHSWVWLTAAQIFGLLFASCQPEELIQKWKGKKAKKKTSDPVAVKFLTSDLDQKMKSFSLASCHQLHSRFLDASLGEQVVKNLLFIAKVLYLLELDSENKQERLKDSEEQDTLGDALAREAAEEKAAADGKTESSREEKEEPSKPATLMWLIQKLSRMAKLEAAYSPRNPLKRTCIFKFLGAVAVDLGVDRVKPYLPVIIAPLFRELNSTYSEQDPVLKNLSQEIIELLKKLVGLESFSLAFASVQKQASEKRALRKKRKALEFVTNPDIAAKKKLKKHKNKSEAKKRKIEFLRPGYKAKRQKSHSLRDLAMVE", "length": 2795 }, "evidence": [ { "id": "A0A8V0YC22", "url": "https://omabrowser.org/oma/group/A0A8V0YC22/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75691-1", "protein_name": "Small subunit processome component 20 homolog", "gene_name": "UTP20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKTKPVSHKTENTYRFLTFAERLGNVNIDIIHRIDRTASYEEEVETYFFEGLLKWRELNLTEHFGKFYKEVIDKCQSFNQLVYHQNEIVQSLKTHLQVKNSFAYQPLLDLVVQLARDLQMDFYPHFPEFFLTITSILETQDTELLEWAFTSLSYLYKYLWRLMVKDMSSIYSMYSTLLAHKKLHIRNFAAESFTFLMRKVSDKNALFNLMFLDLDKHPEKVEGVGQLLFEMCKGVRNMFHSCTGQAVKLILRKLGPVTETETQLPWMLIGETLKNMVKSTVSYISKEHFGTFFECLQESLLDLHTKVTKTNCCESSEQIKRLLETYLILVKHGSGTKIPTPADVCKVLSQTLQVASLSTSCWETLLDVISALILGENVSLPETLIKETIEKIFESRFEKRLIFSFSEVMFAMKQFEQLFLPSFLSYIVNCFLIDDAVVKDEALAILAKLILNKAAPPTAGSMAIEKYPLVFSPQMVGFYIKQKKTRSKGRNEQFPVLDHLLSIIKLPPNKDTTYLSQSWAALVVLPHIRPLEKEKVIPLVTGFIEALFMTVDKGSFGKGNLFVLCQAVNTLLSLEESSELLHLVPVERVKNLVLTFPLEPSVLLLTDLYYQRLALCGCKGPLSQEALMELFPKLQANISTGVSKIRLLTIRILNHFDVQLPESMEDDGLSERQSVFAILRQAELVPATVNDYREKLLHLRKLRHDVVQTAVPDGPLQEVPLRYLLGMLYINFSALWDPVIELISSHAHEMENKQFWKVYYEHLEKAATHAEKELQNDMTDEKSVGDESWEQTQEGDVGALYHEQLALKTDCQERLDHTNFRFLLWRALTKFPERVEPRSRELSPLFLRFINNEYYPADLQVAPTQDLRRKGKGMVAEEIEEEPAAGDDEELEEEAVPQDESSQKKKTRRAAAKQLIAHLQVFSKFSNPRALYLESKLYELYLQLLLHQDQMVQKITLDCIMTYKHPHVLPYRENLQRLLEDRSFKEEIVHFSISEDNAVVKTAHRADLFPILMRILYGRMKNKTGSKTQGKSASGTRMAIVLRFLAGTQPEEIQIFLDLLFEPVRHFKNGECHSAVIQAVEDLDLSKVLPLGRQHGILNSLEIVLKNISHLISAYLPKILQILLCMTATVSHILDQREKIQLRFINPLKNLRRLGIKMVTDIFLDWESYQFRTEEIDAVFHGAVWPQISRLGSESQYSPTPLLKLISIWSRNARYFPLLAKQKPGHPECDILTNVFAILSAKNLSDATASIVMDIVDDLLNLPDFEPTETVLNLLVTGCVYPGIAENIGESITIGGRLILPHVPAILQYLSKTTISAEKVKKKKNRAQVSKELGILSKISKFMKDKEQSSVLITLLLPFLHRGNIAEDTEVDILVTVQNLLKHCVDPTSFLKPIAKLFSVIKNKLSRKLLCTVFETLSDFESGLKYITDVVKLNAFDQRHLDDINFDVRFETFQTITSYIKEMQIVDVNYLIPVMHNCFYNLELGDMSLSDNASMCLMSIIKKLAALNVTEKDYREIIHRSLLEKLRKGLKSQTESIQQDYTTILSCLIQTFPNQLEFKDLVQLTHYHDPEMDFFENMKHIQIHRRARALKKLAKQLMEGKVVLSSKSLQNYIMPYAMTPIFDEKMLKHENITTAATEIIGAICKHLSWSAYMYYLKHFIHVLQTGQINQKLGVSLLVIVLEAFHFDHKTLEEQMGKIENEENAIEAIELPEPEAMELERVDEEEKEYTCKSLSDNGQPGTPDPADSGGTSAKESECITKPVSFLPQNKEEIERTIKNIQGTITGDILPRLHKCLASTTKREEEHKLVKSKVVNDEEVVRVPLAFAMVKLMQSLPQEVMEANLPSILLKVCALLKNRAQEIRDIARSTLAKIIEDLGVHFLLYVLKELQTTLVRGYQVHVLTFTVHMLLQGLTNKLQVGDLDSCLDIMIEIFNHELFGAVAEEKEVKQILSKVMEARRSKSYDSYEILGKFVGKDQVTKLILPLKEILQNTTSLKLARKVHETLRRITVGLIVNQEMTAESILLLSYGLISENLPLLTEKEKNPVAPAPDPRLPPQSCLLLPPTPVRGGQKAVVSRKTNMHIFIESGLRLLHLSLKTSKIKSSGECVLEMLDPFVSLLIDCLGSMDVKVITGALQCLIWVLRFPLPSIETKAEQLTKHLFLLLKDYAKLGAARGQNFHLVVNCFKCVTILVKKVKSYQITEKQLQVLLAYAEEDIYDTSRQATAFGLLKAILSRKLLVPEIDEVMRKVSKLAVSAQSEPARVQCRQVFLKYILDYPLGDKLRPNLEFMLAQLNYEHETGRESTLEMIAYLFDTFPQGLLHENCGMFFIPLCLMTINDDSATCKKMASMTIKSLLGKISLEKKDWLFDMVTTWFGAKKRLNRQLAALICGLFVESEGVDFEKRLGTVLPVIEKEIDPENFKDIMEETEEKAADRLLFSFLTLITKLIKECNIIQFTKPAETLSKIWSHVHSHLRHPHNWVWLTAAQIFGLLFASCQPEELIQKWNTKKTKKHLPEPVAIKFLASDLDQKMKSISLASCHQLHSKFLDQSLGEQVVKNLLFAAKVLYLLELYCEDKQSKIKEDLEEQEALEDGVACADEKAESDGEEKEEVKEELGRPATLLWLIQKLSRIAKLEAAYSPRNPLKRTCIFKFLGAVAMDLGIDKVKPYLPMIIAPLFRELNSTYSEQDPLLKNLSQEIIELLKKLVGLESFSLAFASVQKQANEKRALRKKRKALEFVTNPDIAAKKKMKKHKNKSEAKKRKIEFLRPGYKAKRQKSHSLKDLAMVE", "length": 2785 }, "evidence": [ { "id": "A0A8V0YC22", "url": "https://omabrowser.org/oma/group/A0A8V0YC22/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35194-1", "protein_name": "U3 small nucleolar RNA-associated protein 20", "gene_name": "UTP20", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKQRQTTKSSKRYRYSSFKARIDDLKIEPARNLEKRVHDYVESSHFLASFDQWKEINLSAKFTEFAAEIEHDVQTLPQILYHDKKIFNSLVSFINFHDEFSLQPLLDLLAQFCHDLGPDFLKFYEEAIKTLINLLDAAIEFESSNVFEWGFNCLAYIFKYLSKFLVKKLVLTCDLLIPLLSHSKEYLSRFSAEALSFLVRKCPVSNLREFVRSVFEKLEGDDEQTNLYEGLLILFTESMTSTQETLHSKAKAIMSVLLHEALTKSSPERSVSLLSDIWMNISKYASIESLLPVYEVMYQDFNDSLDATNIDRILKVLTTIVFSESGRKIPDWNKITILIERIMSQSENCASLSQDKVAFLFALFIRNSDVKTLTLFHQKLFNYALTNISDCFLEFFQFALRLSYERVFSFNGLKFLQLFLKKNWQSQGKKIALFFLEVDDKPELQKVREVNFPEEFILSIRDFFVTAEINDSNDLFEIYWRAIIFKYSKLQNTEIIIPLLERIFSTFASPDNFTKDMVGTLLKIYRKEDDASGNNLLKTILDNYENYKESLNFLRGWNKLVSNLHPSESLKGLMSHYPSLLLSLTDNFMLPDGKIRYETLELMKTLMILQGMQVPDLLSSCMVIEEIPLTLQNARDLTIRIKNVGAEFGKTKTDKLVSSFFLKYLFGLLTVRFSPVWTGVFDTLPNVYTKDEALVWKLVLSFIKLPDENQNLDYYQPLLEDGANKVLWDSSVVRLRDTIDTFSHIWSKYSTQNTSIISTTIERRGNTTYPILIRNQALKVMLSIPQVAENHFVDIAPFVYNDFKTYKDEEDMENERVITGSWTEVDRNVFLKTLSKFKNIKNVYSATELHDHLMVLLGSRNTDVQKLALDALLAYKNPTLNKYRDNLKNLLDDTLFKDEITTFLTENGSQSIKAEDEKVVMPYVLRIFFGRAQVPPTSGQKRSRKIAVISVLPNFKKPYINDFLSLASERLDYNYFFGNSHQINSSKATLKTIRRMTGFVNIVNSTLSVLRTNFPLHTNSVLQPLIYSIAMAYYVLDTESTEEVHLRKMASNLRQQGLKCLSSVFEFVGNTFDWSTSMEDIYAVVVKPRISHFSDENLQQPSSLLRLFLYWAHNPSLYQFLYYDEFATATALMDTISNQHVKEAVIGPIIEAADSIIRNPVNDDHYVDLVTLICTSCLKILPSLYVKLSDSNSISTFLNLLVSITEMGFIQDDHVRSRLISSLISILKGKLKKLQENDTQKILKILKLIVFNYNCSWSDIEELYTTISSLFKTFDERNLRVSLTELFIELGRKVPELESISKLVADLNSYSSSRMHEYDFPRILSTFKGLIEDGYKSYSELEWLPLLFTFLHFINNKEELALRTNASHAIMKFIDFINEKPNLNEASKSISMLKDILLPNIRIGLRDSLEEVQSEYVSVLSYMVKNTKYFTDFEDMAILLYNGDEEADFFTNVNHIQLHRRQRAIKRLGEHAHQLKDNSISHYLIPMIEHYVFSDDERYRNIGNETQIAIGGLAQHMSWNQYKALLRRYISMLKTKPNQMKQAVQLIVQLSVPLRETLRIVRDGAESKLTLSKFPSNLDEPSNFIKQELYPTLSKILGTRDDETIIERMPIAEALVNIVLGLTNDDITNFLPSILTNICQVLRSKSEELRDAVRVTLGKISIILGAEYLVFVIKELMATLKRGSQIHVLSYTVHYILKSMHGVLKHSDLDTSSSMIVKIIMENIFGFAGEEKDSENYHTKVKEIKSNKSYDAGEILASNISLTEFGTLLSPVKALLMVRINLRNQNKLSELLRRYLLGLNHNSDSESESILKFCHQLFQESEMSNSPQIPKKKVKDQVDEKEDFFLVNLESKSYTINSNSLLLNSTLQKFALDLLRNVITRHRSFLTVSHLEGFIPFLRDSLLSENEGVVISTLRILITLIRLDFSDESSEIFKNCARKVLNIIKVSPSTSSELCQMGLKFLSAFIRHTDSTLKDTALSYVLGRVLPDLNEPSRQGLAFNFLKALVSKHIMLPELYDIADTTREIMVTNHSKEIRDVSRSVYYQFLMEYDQSKGRLEKQFKFMVDNLQYPTESGRQSVMELINLIITKANPALLSKLSSSFFLALVNVSFNDDAPRCREMASVLISTMLPKLENKDLEIVEKYIAAWLKQVDNASFLNLGLRTYKVYLKSIGFEHTIELDELAIKRIRYILSDTSVGSEHQWDLVYSALNTFSSYMEATESVYKHGFKDIWDGIITCLLYPHSWVRQSAANLVHQLIANKDKLEISLTNLEIQTIATRILHQLGAPSIPENLANVSIKTLVNISILWKEQRTPFIMDVSKQTGEDLKYTTAIDYMVTRIGGIIRSDEHRMDSFMSKKACIQLLALLVQVLDEDEVIAEGEKILLPLYGYLETYYSRAVDEEQEELRTLSNECLKILEDKLQVSDFTKIYTAVKQTVLERRKERRSKRAILAVNAPQISADKKLRKHARSREKRKHEKDENGYYQRRNKRKRA", "length": 2493 }, "evidence": [ { "id": "A0A8V0YC22", "url": "https://omabrowser.org/oma/group/A0A8V0YC22/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54XB2-1", "protein_name": "HEAT repeat-containing protein", "gene_name": "utp20", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPINKNNENSGDNDNMISNNKKKKLLFEAESVQDEYYDVDTNRDDKSRSKVNSFRYQSFSEKISKVDINIFNKVGDVLIELEHENDSYFHQSIMTWRELNLTQHYNNFFIHIRKYHNSLPEIIIHKDKIIDILLQHISIKNSTALKPLLSILASLSRDLRSEFYGSFFKVLKVLITVLKNSFQSESIEEIYTSICFIFKFLEKQILPNFTQLFEIYSELFLQKRKYIRKFAAESIAFFLRKISFEEFELTLNYLFGQLSINNQSEEFIDAFSILLFHSVKGVKGKFHSRTEHILPLMLRQLDSKNIKNCQYECKFRVIVRLFQLIKNHAVNEGDNLKPIWITLKKESNEIFNLIKIFQQQQQQQNNISSGNNKELLNLSSQLEAYFNIIKDWMNGSKMIDVNDIFIILSNFFENGLILKTIIENEFNSSNLLIVLAKAYPISIKYSGSGNSGKKELMLKYLDNLFSLQNIKNSHLLIFQFCTSLKKSNLQDTIITNRLVKYLDKNSSTLDINEMLAFIIRVFTLDENDEPLPISLYPSYEIPNLLKKLESLLINFNKNFNVISSNSSDDNDSNHGCNFNFGSIWSIVSSLVCIYSKSIIEILPILENTTILIESLINNSNSTISKDSQEYQNLIYLLSQSLSSYIILLSKHSKTTNKLAQLSKRIFNLLSNFSNNINILKLSSIYFEKLKDFEQITPPIPITTTVEKKSLTKKSTTTTTTTTKSITPVEPIKFEIFKNHLELLKLNLTNKSNSIRRETISTLKYLHLCTVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNDTTSSTISTQEENDEIQRLFDYCFEIETAQYHLRDARSVVSKVDAIGSIYSNGKIPYFNDLLYHYMMGGFYIRFTPIWSAIQKNIILFCKKDINKFYPILYKTLQNSEQTLLNLNKDKMIIDNEKENEHDEEDVELIEDEDEDENNEVEEEKEKVEKEIEEEEEEEEEEEIKLIENISFEKLIIKDKLNLNYLFNEILDRLYMENSEMIEKSARNILLLSTDPINYNSTLWKTMSMLGSLVEAQSKDLIQMFLEFVYFDFNRFTKVFKNSSSGDSFDFGESIIKVAQTRDQSIIKPYSKTQAEQLFLYYLEFFSQFKRPTKMYQQDLMKQLFYRCLDIDEPKIQFQTLQCYLLWANPSIQPYKKNLERLIHDKTMREEMTTFIISKGSPNTSITDDHRVEIVEVVVKILISKLNRKVTRSSIDAQRITIFSYFSGLSSDELKPIIKRLLQPFSLLLNSLNENVNSGGVTSSNKKIKKSTSLVKEDFSLLPQLDSQVYFLNILQSAVKQLGSLLVPFMDDIIKILLTISKNTLTTTIVNSNDKRPKIISSIRSLAFRRFSEILQQYHSWDFKDYISELFKIISTILPSLNAYGLPVGLRRCLFVVSSNSNLVGYLNQDIKLLPTILSFITYKPHQDSFLSIIENLLLNVDPNEAEPTIIEIYMKVLLPHIDTIINAVKSILLRGNNNKKQKQEQKQQQEQQDISKSGSNFTQPKLNSLNPSKLSKRHLAILSEVSKFAKSAEQASELLELLIPFLRYNKLGDDDDLVLSILVIFKNMLSIIENPDHHIPTLSTLFGVFKTRLTRTTLAEIFLVLGEKVSYMSLISPYLEKLNAYTKKSVHLETYDYDKRLEAYQYINDNLLEKLGHRELLPLFINYVYFINDKDYSIKNSAISGISRLIKSISKKLNENGEVIKSNDQQNTIEIINHFKTIFIQSMRSSFNDKDVRDEFLILFNQLLIDWKGHNQFYPDLKQLLFIGDDEKNFFLNYCHIQKHRKRLSFLQLKNICSINNQDDDGNNNNQDNCKFSNETINHIILPLSIQAILETSIKDHGSAVLGEVVKSLGVLAKSLDWKCYYQVLKKLIKTMDEHPNRFKFFVKSVCEVIDEFHFFINETDVRNELLTGSEIKDDKINNKDENNKEQAEEEEDDEDDDDNEEDEEMGEEEKELREIENDQNNLVTEYNEFDQEENGVLKVSKTKAQSILKIRKKKVIGSTIVKTKNISEEIFQAITTVLTPQLKKHLVEVKVVTSSKMDTGSAAQAEKQKNEGLVNLSIALAILKLYKLLPEKTSSQLYPNIIGKLCIGLKSKEYSVRDTTRSTLLQVMETLGYRFFPYILKDLRNILKNGYQKHILAYTLHALLNTLSKSIEVGVLDSQISLLMDIIIEDLFGEPSVQREIKQVQDTYPEAKTQRSFDSLRIIATIIHFSNTNFMIKPIEEIISVSNSPKLLPNLQEMIKKIGKGLRGNKSLDFKNLSILTYQFITKGLREKEINQFSNRKTITLDTSIGVAHKPTYEETFSIQADPSKKKNSRIHQQETHSFIFAELGFSLLIHAIKSQKSTQLEQYRSMIDPFITYISKCLEHKQPRVVYLSLKCLLKVFNMDLPSVKANSKQLTIQVLKRLQMDSGNEKISNSSYEMATCFLRDEKQEHVNEEQLKAILSLTRQHLTSGEQNLNRSLTMLHVLVNRKVLLPEIYDLMDFCCALMIRSHQPSIATIISNIFIDFLLFYPMGETRLKQQITFLIKNLSYEYDHGRQIVLKTLTQIVERFPQEVLNQYALIIYVPLVVRLTSDPSPSCRENVAQLIKQLIKGVSVQIASKIYDMTMCWFENGSKNLTMARTSAQIIGIQSECSLANFESKLPTIVSKSLPYIEQCLTSLREKEQSFNIIDEISDDAQNSTQLLPGWQLSYSIFTSFEKILTNYPNFSTSTHLSQFWKLSIEFLNYPHIWVRTSLTRLFNIFFTQHSILNLVPIIDQLSTNNNNNNNNNNNKKSNSISPIYNIIFNSNSIFEITKKHCSILNSKLLTDELGLTIIKNLIYLSMLFYKCKNIKPLSNSNDDITPNIFIENIDNNNNDDEMNVDNHEEEEEKEQEEQQVENDDDDDEENDNEQPMEEEEEEKEQQVEEDDEDQIQETTNGKVEQESSMLLWLFKRLSYMSTKAGYLRRKYIFRWIAAVSTQLTVQELIPYLSILLIPLIKCTDEKIRVTPQEKKLAQEVLDILKKKIGPSKFMSVYQSIVKATNEMREKRRADRKIEAIANPKEFLQKKQEKRQLTKEKKRKYKRESLKELLDDRKRIRVSQHLIHGEDD", "length": 3103 }, "evidence": [ { "id": "A0A8V0YC22", "url": "https://omabrowser.org/oma/group/A0A8V0YC22/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5XG71-1", "protein_name": "Small subunit processome component 20 homolog", "gene_name": "Utp20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPKPLSHKTENTYRFLTFAERLGNVNIDIIHRIDRTASYDEDVETYFFEALLKWRELNLTEHFGKFYKEVIDKCQSFNQLVYHQNEIVQSLKTHLQIRNSLAYQPLLDLVVQLARDLQTDFYPHFEDFFLTITSILETQDTELLEWAFTSLSYLYKYLWRLMVKDMSKIYSLYSTLLAHKKLHIRNFAAESFTFLMRKVSDKNALFNLMFLDLNEHPEKVEGVGQLLFEMCKGVRNMFHSCTGQALKLLLQKLGPVTETETQLPWILVGETLKTMAKSSVVYIYKEHFGVFFDCLQESLLELHNKVTEANCCENSEQMRRLLETYLIVVKHGSGSKITRPADVCGVLSEALQTASLSTSCRKTLLDVVSALLLAENVSLPETLIKETVEKVFESKFERRSVLDFSEVMFAMKQFEQLFLPSFLLYIENCFLMDNSVVSDEALAILAKLILHKAPPPTAGSMAIEKYPLVFSQQTVGSYLKQRKADSKRRKEQFPVLSHLLSIVQLPPNKDATYLSRSWAALVVLPHLRPLEKEKTISLVSCFIESLFLAVDRGSFGKGHLFVLCQAVNTLLSLEESSELLHLVPVGRVKHLVLTSPTEPSVLLLADLYYQRLALCGCKGPLSEEALMELFPKLQANISTGVSKIRLLTIRILNHFDIRLPVSMEDDGLSERQSAFAILRQAELVPATVSDYREKLLHLRKLRHDVVQGAVPQGRLQEVPLRYLLGMLYVNFSALWDPVIELISSHAYGMENKQFWNVCYEHLEKAASHAEKELHKDVRDEESTGDESWEQTQEGDVGDLYQQQLALKTDCRERLDHTNFRFLLWRALAKFPERVEPRSRELSPLFLRFINNEYYPADLQVAPTQDLRKKGRGAVAEEEEEEEPAAGEDEELEEEAVPTEDAPQKKKTRRAAAKQLIAHLQVFSKFSNPRALYLESKLYELYLQLLLHQDQAVQKITLDCIMTYRHPHILPYRENLQRLLDDRSFKEEIVHFNISEDNTVVKAAHRADLFPILMRILYGRMKNKTGSKTQGKSASGTRMAIVLRFLAGTQPEEIQLFLDLLSEPVKHFKDGDCCSAVIQAVEDLDVSKVLPVGRQHGVLNSLEVVLKNISHLISTYLPKILQILLCMTATVSHILDQREKIQLRFINPLKNLRRLGIKMVTDIFLDWESYQFKAEEIDAVFHGTVWPQICRLGSESQYSPTPLLKLISIWSRNARYFPLLAKQKPGHPEYDILTNVFAVLSAKNLSEATASIIMDIVDDLLNLPDFQPTEAVPSLPVTGCVYADVAEDTEPVTVGGRLVLPHVPAILQYLSKTTISAEKVKKKKNRAQVSKELGILSKISKFMKDREQCSLLITLLLPFLLRGNVAQDTELDILVTVQNLLQHCLHPAHFLRPLAKLFSVIKNKLSRQLLCTVFQMSDFESRLKYITDIVKLNAFDKRHLDDINFDVRFSAFQTITSNIKAMQTVDADYLIAVMHNCFYNMEIGDMSLSDNASICLTSIIKRLAALNVTEKEYKEIIHRTLLEKLRKGLKSQTESVQHDYTLILSCLIQTFPNQLEFKDLVQLTHCHDPEMDFFENMKHIQIHRRARALKKLAKQLLEGQVVLSSKSLQNYIMPYAMAPILDEKMLKHENITIAATEVIGAICRHLSWPAYVYYLKHFIHVLQSGQINQKLAVSLLVIVLEAFHFDYKTLEEQMGNVKNEENTVEMAELLEPEAMEVEDMDEAGKEQASERLSDSKEALGAPEAAASEGTVAKEQECISKSVSFLPRNKEELERTIQTIQGAITGDILPRLHKCLASATKREEEHKLVKSKVVNDEEVVRVPLAFAMVKLMRSLPREVMEANLPSILLKVCVLLKNRAQEIRDIARSTLSKIIEDLGVHFLQYVLKELQTTLVRGYQVHVLTFTVYTLLQGLSSKLQVGDLDSCLHIMTEIFNHELFGALAEEKEVKQILSKVMEARRSKSYDSYEILGKFVGKQQVTKLILPLKEILQNTTSLKLARKVHETLRRIIAGLIVNPDMTADALLLLSYGLVSENLPLLTEKEKKPAAPVPDARLPPQSCLLLPATPVRGGPKAVVNKKTNMHIFIESGLRLLHLSLKTSRIKSSSEHVLEMLDPFVSVLINCLGAQDVKVITGALQCLIWVLRFPLPSIASKAEQLTKHLFLLLKNYARVGAARGQNFHLVVNCFKCVTIVVKKVKSHQITEKQLQVLLAYAEEDIYDTSRQATAFGLLKAILSRKLLVPEIDDIMRKVSKLAISAQNEPARVQCRQVFLKYILDYPLGEKLRPNLEFMLAQLNYEHETGRESTLEMIAYLFETFPQGLLHEHCGMFFIPLCLMMVNDDSAMCKRMASMAIKSLLSKVDREKKDWLFGLVTSWFEAKKRLNRQLAALACGLFVESEGVDFERRLGTLLPVIEKEIDPENFKDIIEETEEKAADRLLFGFLTLMRKLIKECSIIHFTKPSETLSKIWSHVHSHLRHPHSWVWLTAAQIFGLLFASCQPEELIQKWKGKKTKKKTSDPIAVRFLTSDLGQKMKSISLASCHQLHSKFLDESLGEQVVKNLLFIAKVLYLLELESGNKRGEVKDSEEQDTLADALAREAAEEKAGAGGKMESNREKKEEPSKPATLMWLIQKLSRMAKLEAAYSPRNPLKRTCIFKFLGAVAVDLGVDRVKPYLPLIIAPLFRELNSTFAEQDPVLKNLSQEIIELLKKLVGLESFSLAFASVQKQASEKRALRKKRKALEFVTNPDIAAKKKLKKHKNKSEAKKRKIEFLRPGYKAKRQKSHSLRDLAMVE", "length": 2788 }, "evidence": [ { "id": "A0A8V0YC22", "url": "https://omabrowser.org/oma/group/A0A8V0YC22/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W246-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG4554", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASLAEKTKDTNTFRFKSFGDRVNEIDLRHLALYHIGHRNEELDEEENATYFQQTIQKWNVLNLSEEYNYFSKRCRKIVTLPQLLHQKDFVVDLLLERLSTATNLSQQPLLELLYVLAKDLREEFYPYFQRVLDRLICLLNTQDSEQLEWTLICLAHLFKTLKPYLKRNIGVVFNAILPLLDEQHYAEHVTNFAVECFAYIARDVRDFPRFLTYVLKTVLREQVESVHGCGRLIYEILRGVNGQLHNSAAEIFAHVLEVLVNKDSAHTKDQTELLGDIVEYSLGLLLNFLRSDQSNILWQKLCSAASSESVDEQRVIDLMLPLVTHKDGRYVSELPLVVGTLLKLLDRELDPLQPLTTLVTSLLKAQHTQLSQLDASRLLQKLLSISRKQVTVYEDAILQLLDYSQFEILVLPNVIGYFEEQRQLRARELLARIVLHKRPLKVDGNSLAQWVAYPLQLKQKDTIKLVEQELLHLDLTKEEHLLLIILVPHLRGFNKQPLEQGLQSVIEKLICDNGKDFTQLLLLLQTHALLKFNLPKSLRSSLNGYLIPELGKDIRALACLQVVLLQGPKNELSTSDELLFGIGGLLSQPVSLYRRIAAHCLDVLNSSSKPNPYSHFNAAACIEPTVHNYRELLLQLQQLEPASAQFKQFSQLPHFKEHAVSLLLGLLYNNFKFVWAPVQQLLAAYVKTMTVDEFWTLFKAKLVDTVACIDYKKEVTTLQVPYQRDYQSAALTMLLTLPGEQQLTLQQALNYRQLLWQSVPKLGTLAEVKNADLVRLFLQFVDNEYRAQLEKSEHTWNVNEATAADIDVEEDDENENNETKPEPRGRQKRRTQNAHTKFILQTLQLKLACFVSQPNPKALHRQAEMHDFYLELLAGPNSQLQQLALDCLAAYKQPAALVQQKAQLSGLIDEEKFKTTLSGFELSSITAQQRSELIPFMLRVLYGKMLTKGVQKQLSAQLRKTLILRFLGQLEESEIMDFLQMAFGRFSAYTDKPVDEVAKYARESYDPSAVIAAKQLQRIVNLLELIRKEFAGKLTSDFQCYVLKLLLLVGSVAQEVINGEGKLVAAYKNVKHSGLQTLVNYFGQLVDMEELWQEPQMNAICEVYLWPGIARLSQDSIHTPTPMLKLLLLWGGEPRFQKWLKKSAPADKLPIMHHLMALLLNEKAKPNVKRAILQVVEHLLESAATEEYGAEALSIVHPHIPTILQQLQNSWRHKKAGRQTLDKRELNILTLITSHVEEPDTCELLLQVLLPIFTKQSASAAPETVVQLVTTLGNLLKRVSKPQNYLRQLAPLFEQVSALPARKLLCDLLADMAKQLHKEAKQNPDISPIAASLREWVRIVLLLNAWDKRWLEQPDYDKRLEALSELKQLAEKKDKKIDLQLGVLVVYNCFYMLRNDSDLGMRVNIGELLKPLLPLITLQLEVKEDLHFWLEDTVLPLLQRCMRDEKHEHARSEAIGLLGELARQCPAAHEILKDLSPLTDKYDLEVDFFENMLHLQTQRHGRALQRLVNISGGSWRTVPPCARTLTQFLLPLATRYLMSERHSGKHTLVDAAIEAVGVMSEFLPWTQYQAVLRYYLQKLRHVHSQQKQCVRVVVRILDAFHFDLTQAQTDLVSLAKLKEKLIEAVEAKEPAEESDEVKAEEDAEADEVPVKKEDDQSDFIDFEEEDPNEPVVEQQRTQLLAPNAAKKVMATITTVLLPTLNRSITEKTNYDTKHKVNRRRLSYEREEEEIQRVPIALAMVKLLQKLPLELLENSLPGIFMKVCTFLRSPLKSVRMLTRDILKKIMITLGGSYLGMLLEQLQSLLTRGFQVHVLSVTLHGVLDALKSDLKPEHIENCLQNLLEVALNDIFGDVNAEKEVEKIVAHTPEAKPSAKSYLTLNIAARHIRDNCLLDLLLPFKEHLARSHSRKVTQKIQECFAKIVGGLVENTHIARESLLIFIYGTMSESISDLLPGTKKRQLTEKEQALMKRTRPDCLILQPAPGRRSVATGNKQVKSNAQANAHILVEFGLELLHFVLKRKKLTDLDYQPFLHPLLPLLKDSLSSNHARTTTYALKCYTAIWLGEYELSDLNREALQPVVARMFQILKNFSTFGATRQEENAQLVRASFKAVVALLRKCEDYQLSNEQIEQLLLHIEQELQEGECSSQTMVFTLLKALVGRKVDSRSLHDLMKRLGDLSIISSSDYVRDECRGILLTYIMEYTLRQKVEQIVKFMSVQLCYSQTAGRQSAIQFMHSIINKFPQLMLVKQSEFLYLSLGTRLVNDEDPSCRRSVAAALEALIGRLTKLERQPLLDLTLLFFTAPQSSQKPGVREMAAALLSRFVEAEKAGFAERLPLVLPTLVNVLTLGHAEAGGRFVRAPGYLAAEVDESELHKKNKRKKFKTLPDEDLLLAGLDNESILEQQQRKADHQLIQLQYCLLKIFEHCGESLLNNPQLSDTVDDLAYGSQRLLNHDHNWVRCNAAKLLTHIVAHYDFAYIGQQLSGIKLEAGAKKALYFIYAQPAEDIKSLVLDLCAQVTPGETAQEMIDELSKILLFVGHMLRDVPFSLKQEKNDDEEEREPVNKISLTWLIRNIRFLINKEVAKAPHDISIRTAMFTLIEALSTLLSVESVTRLAPSLLQALVREMSEEDQNVDAELRQQALRVGSRLRKRIGAEVYDKLRNAVQTKLMARRAERRKVVAQEKIHDPERAAKRKAGMQERKKAAKRLKAAVVRGKAPDIKQKLKKRKRKAEMDGF", "length": 2733 }, "evidence": [ { "id": "A0A8V0YC22", "url": "https://omabrowser.org/oma/group/A0A8V0YC22/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" } ], "pmid": "" }, { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1251, "end_pos": 1253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1283, "end_pos": 1285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1500, "end_pos": 1502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1972, "end_pos": 1974, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2114, "end_pos": 2116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2695, "end_pos": 2697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2707, "end_pos": 2709, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" }, { "id": "PF20416", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20416" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 20", "eco_id": "ECO_0000259", "start_pos": 1827, "end_pos": 2043, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" }, { "id": "PF23099", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23099" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 2393, "end_pos": 2778, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC22" }, { "id": "PF07539", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07539" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 20 N-terminal", "eco_id": "ECO_0000259", "start_pos": 918, "end_pos": 1541, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1034, "end_pos": 1036 }, { "start_pos": 1251, "end_pos": 1253 }, { "start_pos": 1283, "end_pos": 1285 }, { "start_pos": 1500, "end_pos": 1502 }, { "start_pos": 1972, "end_pos": 1974 }, { "start_pos": 2114, "end_pos": 2116 }, { "start_pos": 2695, "end_pos": 2697 }, { "start_pos": 2707, "end_pos": 2709 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 789, "end_pos": 791 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YC29-1", "uniprot_ac": "A0A8V0YC29", "uniprot_id": "A0A8V0YC29_CHICK", "mass": { "chemical_mass": 71982.0, "monoisotopic_mass": 71982.0 }, "refseq": { "ac": "XP_040511726", "name": "leucine-rich repeat-containing protein 70", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511726" }, "gene_names": [ { "name": "LRRC70", "type": "recommended", "evidence": [ { "id": "A0A8V0YC29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29" } ] }, { "name": "LRRC70", "type": "synonym", "evidence": [ { "id": "XP_040511726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511726" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 70", "type": "synonym", "evidence": [ { "id": "A0A8V0YC29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 70", "type": "synonym", "evidence": [ { "id": "XP_040511726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511726" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511726" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29", "locus": { "chromosome": "Z", "start_pos": 20106957, "end_pos": 20098060, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011996", "url": "https://www.ensembl.org/id/ENSGALG00010011996" } ] } } ], "crossref": [ { "id": "107049022", "url": "https://www.ncbi.nlm.nih.gov/gene/107049022", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QANYNPW", "url": "https://omabrowser.org/oma/group/QANYNPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC29", "url": "https://www.orthodb.org/?gene=A0A8V0YC29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKC5", "url": "https://www.orthodb.org/?gene=A0A8V0YKC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45773:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45773:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040511726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEKAKDRDMCGLQSFSTCTGAFLHLLSGFLLLLLQNEVLGCPAVCQLCTGRQVTCRNLGLSSIPRNFPKTTMLVYFSGNNISHLIPNELTGLQKLAALYMDNSSISYVHPKAFVDLPKLCYLHLNNNNIKRLDPGVFEGLSNLHYLYLQNNQIAFVPRGLFSDLLSVRYLTLQRNRLSILGSGTFLGMRNLQTLNLANNKISRISDAAFCHLENLVYLFLEGNNLTLVPSNAIGRLENLERLSLSHNPIRSIQRFAFKGLNKLRYLSLKSVKLKHIAVNGFFGLSNLSQLILSYNDLENINSSSFTSLNSLKYLQLDRNKITTISDGVFEKMGQSLKILNLAFNNITELQLKVLEPLVSLTHLHMNYNPWNCSCKMFGLLKWLSSSPISVKILCWNPLSMRGRPLHYIRWTQFANCSGVTPSPEAAWNVESLDTHHSPSTLLMAWHKGNRHSPFEEFVKADKKFIALWEGTAATSTSPLPYRGNTAAGIHSQAPTVLSVLPVQISAQIIPVTGTIEVKSLFPTDAAPVSLQTSVLCTQQVEKLNQAFDVLLAFFVLACAVILFLTYRIIHFRQKLKVLENSGEKRIEYYGFYQPGRYNINDAVQSLTENSVGDSELDQIRLLKRTASESQAQVILFEHSSL", "length": 642, "header": "tr|A0A8V0YC29-1|A0A8V0YC29_CHICK Isoform 1 of Leucine rich repeat containing 70 OS=Gallus gallus OX=9031 GN=LRRC70 PE=3 SV=1 CANONICAL=A0A8V0YC29-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29/entry#A0A8V0YC29-1", "sequence": { "sequence": "MSEKAKDRDMCGLQSFSTCTGAFLHLLSGFLLLLLQNEVLGCPAVCQLCTGRQVTCRNLGLSSIPRNFPKTTMLVYFSGNNISHLIPNELTGLQKLAALYMDNSSISYVHPKAFVDLPKLCYLHLNNNNIKRLDPGVFEGLSNLHYLYLQNNQIAFVPRGLFSDLLSVRYLTLQRNRLSILGSGTFLGMRNLQTLNLANNKISRISDAAFCHLENLVYLFLEGNNLTLVPSNAIGRLENLERLSLSHNPIRSIQRFAFKGLNKLRYLSLKSVKLKHIAVNGFFGLSNLSQLILSYNDLENINSSSFTSLNSLKYLQLDRNKITTISDGVFEKMGQSLKILNLAFNNITELQLKVLEPLVSLTHLHMNYNPWNCSCKMFGLLKWLSSSPISVKILCWNPLSMRGRPLHYIRWTQFANCSGVTPSPEAAWNVESLDTHHSPSTLLMAWHKGNRHSPFEEFVKADKKFIALWEGTAATSTSPLPYRGNTAAGIHSQAPTVLSVLPVQISAQIIPVTGTIEVKSLFPTDAAPVSLQTSVLCTQQVEKLNQAFDVLLAFFVLACAVILFLTYRIIHFRQKLKVLENSGEKRIEYYGFYQPGRYNINDAVQSLTENSVGDSELDQIRLLKRTASESQAQVILFEHSSL", "length": 642, "header": "tr|A0A8V0YC29-1|A0A8V0YC29_CHICK Isoform 1 of Leucine rich repeat containing 70 OS=Gallus gallus OX=9031 GN=LRRC70 PE=3 SV=1 CANONICAL=A0A8V0YC29-1" }, "locus": { "chromosome": "Z", "start_pos": 20101168, "end_pos": 20099243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028709.1", "url": "https://www.ensembl.org/id/ENSGALT00010028709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016512.1", "url": "https://www.ensembl.org/id/ENSGALP00010016512.1" } ] } }, { "isoform_ac": "A0A8V0YKC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29/entry#A0A8V0YKC5-1", "sequence": { "sequence": "MSEKAKDRDMCGLQSFSTCTGAFLHLLSGFLLLLLQNEVLGCPAVCQLCTGRQVTCRNLGLSSIPRNFPKTTMLVYFSGNNISHLIPNELTGLQKLAALYMDNSSISYVHPKAFVDLPKLCYLHLNNNNIKRLDPGVFEGLSNLHYLYLQNNQIAFVPRGLFSDLLSVRYLTLQRNRLSILGSGTFLGMRNLQTLNLANNKISRISDAAFCHLENLVYLFLEGNNLTLVPSNAIGRLENLERLSLSHNPIRSIQRFAFKGLNKLRYLSLKSVKLKHIAVNGFFGLSNLSQLILSYNDLENINSSSFTSLNSLKYLQLDRNKITTISDGVFEKMGQSLKILNLAFNNITELQLKVLEPLVSLTHLHMNYNPWNCSCKMFGLLKWLSSSPISVKILCWNPLSMRGRPLHYIRWTQFANCSGVTPSPEAAWNVESLDTHHSPSTLLMAWHKGNRHSPFEEFVKADKKFIALWEGTAATSTSPLPYRGNTAAGIHSQAPTVLSVLPVQISAQIIPVTGTIEVKSLFPTDAAPVSLQTSVLCTQQVEKLNQAFDVLLAFFVLACAVILFLTYRIIHFRQKLKVLENSGEKRIEYYGFYQPGRYNINDAVQSLTENSVGDSELDQIRLLKRTASESQAQELIWK", "length": 638, "header": "tr|A0A8V0YKC5-1|A0A8V0YC29_CHICK Computationally mapped isoform of Leucine rich repeat containing 70 OS=Gallus gallus OX=9031 GN=LRRC70 PE=3 SV=1 CANONICAL=A0A8V0YC29-1" }, "locus": { "chromosome": "Z", "start_pos": 20101806, "end_pos": 20099243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028711.1", "url": "https://www.ensembl.org/id/ENSGALT00010028711.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016513.1", "url": "https://www.ensembl.org/id/ENSGALP00010016513.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 421, "start_aa": "Thr", "end_pos": 421, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr421", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AYQ3-1", "protein_name": "Leucine rich repeat containing 70", "gene_name": "LRRC70", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNRKTKNRAMCGVRFSLLCLRLFLLVACYLVLLFHKEILGCSSVCQLCTGRQINCRNLGLSSIPKKFPESTVFLYLTGNNISHINENELTGLHSLIALYLDNSSIVYVYPKAFVHLRHLYFLYLNNNFIKRLDPGIFEGLSNLRNLYLQSNQISFVPRGVFHDLVSVQYLNLQRNRLTILGSGTFVGMVALRILDLSNNKILRISDSGFQHLENLNCLYLEGNNLTKVPSNAFEILKSLKRLSLSHNHIEAIQPFAFKGLVNLEYLLLKNSGIKNVTRNGFNGINNLRYLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTDLHPRVLKPLSSLTHLQANSNPWECNCKLLGLRDWLASSAITLNIYCQSPPSMRGRALHYIKWTDFTNCVTSSTNASRAWAIKSLHIHHKTTALMMAWHRITTDGKHLENNESVTFWERIRTSPASRFFQENAFGNPLETTAVLPVQIQLTSPVNLNLEKNSALPVDAASVSGKTSLICTQEVEKLNEAFDILLAFFILACVLIVFLIYKVVQFKQKLKAPENSGDNRLEYYSFYQSARYNVTASFCSTSPNSLEGPGLEQIRLHKQIVPESEAQVILFEHSAL", "length": 631 }, "evidence": [ { "id": "A0A8V0YC29", "url": "https://omabrowser.org/oma/group/A0A8V0YC29/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z2Q7-1", "protein_name": "Leucine-rich repeat-containing protein 70", "gene_name": "LRRC70", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCGLQFSLPCLRLFLVVTCYLLLLLHKEILGCSSVCQLCTGRQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLGLRDWLASSAITLNIYCQNPPSMRGRALRYINITNCVTSSINVSRAWAVVKSPHIHHKTTALMMAWHKVTTNGSPLENTETENITFWERIPTSPAGRFFQENAFGNPLETTAVLPVQIQLTTSVTLNLEKNSALPNDAASMSGKTSLICTQEVEKLNEAFDILLAFFILACVLIIFLIYKVVQFKQKLKASENSRENRLEYYSFYQSARYNVTASICNTSPNSLESPGLEQIRLHKQIVPENEAQVILFEHSAL", "length": 622 }, "evidence": [ { "id": "A0A8V0YC29", "url": "https://omabrowser.org/oma/group/A0A8V0YC29/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of response to cytokine stimulus", "id": "GO:0060760", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060760", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YC29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC29" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 369, "end_pos": 418, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 421 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149024", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149024" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMCO6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC30", "locus": { "chromosome": "13", "start_pos": 853254, "end_pos": 846738, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011670", "url": "https://www.ensembl.org/id/ENSGALG00010011670" } ] } } ], "crossref": [ { "id": "A0A8V0YC30", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YC30", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0YC30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGRRRGAGPGGGAEELRARRREREAALRKARREQQLVSKRLLREDEAERGHDGAGDAAEAVLEPVLQGEVSELLRGVQRGSEDRRRWLRCLRRALQSKETQQEFVRLDGAVRTLVGLFTCSLPDVQLEAARCLHELSHSSDAAVAEACVPVTSYLLTYLSGHSIELMELCLYTLGNLVVESEVVRKKLLPQGIIPVLASCIQSPHEAVLEGLGYVLSQLLQAKEAPAEIIPLVLDSVLPQHMLRLVCSGLKFGTGAAVEFAWCLHYIVCSHTANVELMSLGAVPALTSLLCDIAFEISQSDSEGLELLICPVLRCLGNLLAEETGHEVQPQDERLLVALFVVMQCYLQQHPFIIPESLWLINNLTADEPFFCSALLSMDLLPALLQLLPHSQTVSVLVLTVLCNIAEKGPAYCQQLHQQAALPLLLHVLMVPDPEVVGQCLELLHLLFLHWPQVAVDFVRQGGHQTLEQHQSTPELQERVRALLDMALQPQDASVFSSPSAASSTFSQMM", "length": 511, "header": "tr|A0A8V0YC30-1|A0A8V0YC30_CHICK Isoform 1 of Transmembrane and coiled-coil domains 6 OS=Gallus gallus OX=9031 GN=TMCO6 PE=4 SV=1 CANONICAL=A0A8V0YC30-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC30/entry#A0A8V0YC30-1", "sequence": { "sequence": 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"MWSRRQGRLRPTVCGVEELRRRRREREAALRKARREQQLVSKRLLRNDAPEEAGEGCVAAILGETEVQQFLRQAQRGTEEKEREGALVSLRRGLQHPETQQTFIRLEGSMRTLVGLLTSNQALLQLEAARCLHELSHSEQSTVAEACLPATSYLLTYLSSHSSDFIELCLYTLGNLIVESEAVRRQLLPQGIVPALAACIQSPHVAVLEALGYALSQLLQAEEAPEKIIPSILASTLPQHMLQMLQPGPKLNPGVAVEFAWCLHYIICSQVSNPLLIGHGALSTLGLLLLDLAGAVQKTEDAGLELLACPVLRCLSNLLTEAAVETVGGQMQLRDERVVAALFILLQFFFQKQPSLLPEGLWLLNNLTANSPSFCTSLLSLDLIEPLLQLLPVSNVVSVMVLTVLCNVAEKGPAYCQRLWPGPLLPALLHTLAFSDTEVVGQSLELLHLLFLYQPEAVQVFLQQSGLQALERHQEEAQLQDRVYALQQTALQG", "length": 493 }, "evidence": [ { "id": "A0A8V0YC30", "url": "https://omabrowser.org/oma/group/A0A8V0YC30/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC30", "url": 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{ "id": "cd03467", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03467", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR017941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC38", "url": "https://www.orthodb.org/?gene=A0A8V0YC38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21496", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21496", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21496:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21496:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22543", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22543", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YC38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALHSPSKGTVEPEPDGLVLVGKEDDIKKSQRITAKVNGREVVVFYHEGRFYALDSRCYHEGGPLHLGEIEDIDGQPCIICPWHKYTITLETGEGLYQGINPLEPSPTPRWQSKGEKQRIHKVTVKNKNVYVSPPDLSVSFDSDYFAEKYKNGGDLAMKK", "length": 160, "header": "tr|A0A8V0YC38-1|A0A8V0YC38_CHICK Isoform 1 of Rieske domain-containing protein OS=Gallus gallus OX=9031 GN=RFESD PE=4 SV=1 CANONICAL=A0A8V0YC38-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC38/entry#A0A8V0YC38-1", "sequence": { "sequence": "MALHSPSKGTVEPEPDGLVLVGKEDDIKKSQRITAKVNGREVVVFYHEGRFYALDSRCYHEGGPLHLGEIEDIDGQPCIICPWHKYTITLETGEGLYQGINPLEPSPTPRWQSKGEKQRIHKVTVKNKNVYVSPPDLSVSFDSDYFAEKYKNGGDLAMKK", "length": 160, "header": "tr|A0A8V0YC38-1|A0A8V0YC38_CHICK Isoform 1 of Rieske domain-containing protein OS=Gallus gallus OX=9031 GN=RFESD PE=4 SV=1 CANONICAL=A0A8V0YC38-1" }, "locus": { "chromosome": "Z", "start_pos": 58223925, "end_pos": 58222865, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031422.1", "url": "https://www.ensembl.org/id/ENSGALT00010031422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018341.1", "url": "https://www.ensembl.org/id/ENSGALP00010018341.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC38" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YC38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC38" }, { "id": "PS51296", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rieske", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 120, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 108 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YC62-1", "uniprot_ac": "A0A8V0YC62", "uniprot_id": "A0A8V0YC62_CHICK", "mass": { "chemical_mass": 133759.0, "monoisotopic_mass": 133759.0 }, "refseq": { "ac": "XP_015137689", "name": "RAB11-binding protein RELCH isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137689" }, "gene_names": [ { "name": "KIAA1468", "type": "recommended", "evidence": [ { "id": "A0A8V0YC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62" } ] }, { "name": "KIAA1468", "type": "synonym", "evidence": [ { "id": "XP_015137689", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137689" } ] } ], "protein_names": [ { "name": "LisH domain and HEAT repeat-containing protein KIAA1468", "type": "recommended", "evidence": [ { "id": "A0A8V0YC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62/entry#names_and_taxonomy" } ] }, { "name": "RAB11-binding protein RELCH isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015137689", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137689" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137689" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA1468", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62", "locus": {} } ], "crossref": [ { "id": "A0A8V0YC62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YC62", "database": "AlphaFoldDB", "categories": [] }, { "id": "420907", "url": "https://www.ncbi.nlm.nih.gov/gene/420907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420907", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQDLNCA", "url": "https://omabrowser.org/oma/group/RQDLNCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC58", "url": "https://www.orthodb.org/?gene=A0A8V0YC58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC62", "url": "https://www.orthodb.org/?gene=A0A8V0YC62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDD1", "url": "https://www.orthodb.org/?gene=A0A8V0YDD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFL2", "url": "https://www.orthodb.org/?gene=A0A8V0YFL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32059", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32059", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32059:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32059:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015137689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137689", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGGGSSVNPFLSDSEEDEPEEARPGGGGGSSSSTEPGGPAYPARRREEVAAVGSPEELPGLRAAGDAAAGAGGGAAAGEPPRVSMDAMAAQLLRDQFLLTALELHTELLESGRELPRLRDFFSNPGNFERQSGTPPAGGGLGGSVLGGAGGREPGSGQLNRAGSISTLDSLDFARYSDDGNRETDERVAVLEFELRKAKETIQALRANLTQAAENEVPLQERKNYKSSPEIQEPIRPLEKRALNFLVNEFLLKNSYKLTSITFSDENHDQDFELWDDVGLNIPKPPDLLQLYRDFGNHHVTARDVVDVSVGVDDDELEATTPILGTVPVFETTPQSIEQCLIVQKLEDQISVLNNEKWSLMEQIQRLESEIDFLKNENFAVSTVYGVAPHPSLKQVPHTDSEDNGRYLDIKSSENDSKHGNTEEKSLSSSAEHDTRTSKDDTLNSVPCKDPEKVSSCAPSKKTAVHFDKPNRKLSPAFHQALLSFCRMSADSRLGSEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQFHLIPTLLSKIEKLLREGEHGLDEHKLHTYLSALQSLIPSLFALVLQNAPFTSKAKLQGEVPQIEVTRFPRPASPLQDVAIIIGSREQLAVLLQLYNHQLEHEGTTGWETLLWVVNQLLPQLIEIVGKINVASTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSTAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTMLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFELLVKGVHETLVAQRVVPALITLSSDPEISVRIATIPAFGTIMETVTQRELLERVKMQLASFLEDPQYQDQHSLHTEIIKTFGRVGPNAEPRFRDEFVIPHLHKLALVNNQQSVDSKRLDIATHLFEAYSALSCCFISEDLMVNHFLPGLKCLRIDMEHLSPEHEVILSSMIKECEQKVENKTVQEPQGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK", "length": 1208, "header": "tr|A0A8V0YC62-1|A0A8V0YC62_CHICK Isoform 1 of LisH domain and HEAT repeat-containing protein KIAA1468 OS=Gallus gallus OX=9031 GN=KIAA1468 PE=1 SV=1 CANONICAL=A0A8V0YC62-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62/entry#A0A8V0YC58-1", "sequence": { "sequence": "MDAMAAQLLRDQFLLTALELHTELLESGRELPRLRDFFSNPGNFERQSGTPPAGGGLGGSVLGGAGGREPGSGQLNRAGSISTLDSLDFARYSDDGNRETDERVAENEVPLQERKNYKSSPEIQEPIRPLEKRALNFLVNEFLLKNSYKLTSITFSDENHDQDFELWDDVGLNIPKPPDLLQLYRDFGNHHVTARDVVDVSVGVDDDELEATTPILGTVPVFETTPQSIEQCLIVQKLEDQISVLNNEKWSLMEQIQRLESEIDFLKNENFAVSTVYGVAPHPSLKQVPHTDSEDNGRYLDIKSSENDSKHGNTEEKSLSSSAEHDTRTSKDDTLNSVPCKDPEKVSSCAPSKKTAVHFDKPNRKLSPAFHQALLSFCRMSADSRLGSEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQFHLIPTLLSKIEKLLREGEHGLDEHKLHTYLSALQSLIPSLFALVLQNAPFTSKAKLQGEVPQIEVTRFPRPASPLQDVAIIIGSREQLAVLLQLYNHQLEHEGTTGWETLLWVVNQLLPQLIEIVGKINVASTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSTAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTMLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFELLVKGVHETLVAQRVVPALITLSSDPEISVRIATIPAFGTIMETVTQRELLERVKMQLASFLEDPQYQDQHSLHTEIIKTFGRVGPNAEPRFRDEFVIPHLHKLALVNNQQSVDSKRLDIATHLFEAYSALSCCFISEDLMVNHFLPGLKCLRIDMEHLSPEHEVILSSMIKECEQKVENKTVQEPQGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK", "length": 1097, "header": "tr|A0A8V0YC58-1|A0A8V0YC62_CHICK Computationally mapped isoform of LisH domain and HEAT repeat-containing protein KIAA1468 OS=Gallus gallus OX=9031 GN=KIAA1468 PE=1 SV=1 CANONICAL=A0A8V0YC62-1" }, "locus": { "chromosome": "2", "start_pos": 68056749, "end_pos": 67983274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028755.1", "url": "https://www.ensembl.org/id/ENSGALT00010028755.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016543.1", "url": "https://www.ensembl.org/id/ENSGALP00010016543.1" } ] } }, { "isoform_ac": "A0A8V0YC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62/entry#A0A8V0YC62-1", "sequence": { "sequence": "MAAAGGGSSVNPFLSDSEEDEPEEARPGGGGGSSSSTEPGGPAYPARRREEVAAVGSPEELPGLRAAGDAAAGAGGGAAAGEPPRVSMDAMAAQLLRDQFLLTALELHTELLESGRELPRLRDFFSNPGNFERQSGTPPAGGGLGGSVLGGAGGREPGSGQLNRAGSISTLDSLDFARYSDDGNRETDERVAVLEFELRKAKETIQALRANLTQAAENEVPLQERKNYKSSPEIQEPIRPLEKRALNFLVNEFLLKNSYKLTSITFSDENHDQDFELWDDVGLNIPKPPDLLQLYRDFGNHHVTARDVVDVSVGVDDDELEATTPILGTVPVFETTPQSIEQCLIVQKLEDQISVLNNEKWSLMEQIQRLESEIDFLKNENFAVSTVYGVAPHPSLKQVPHTDSEDNGRYLDIKSSENDSKHGNTEEKSLSSSAEHDTRTSKDDTLNSVPCKDPEKVSSCAPSKKTAVHFDKPNRKLSPAFHQALLSFCRMSADSRLGSEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQFHLIPTLLSKIEKLLREGEHGLDEHKLHTYLSALQSLIPSLFALVLQNAPFTSKAKLQGEVPQIEVTRFPRPASPLQDVAIIIGSREQLAVLLQLYNHQLEHEGTTGWETLLWVVNQLLPQLIEIVGKINVASTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSTAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTMLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFELLVKGVHETLVAQRVVPALITLSSDPEISVRIATIPAFGTIMETVTQRELLERVKMQLASFLEDPQYQDQHSLHTEIIKTFGRVGPNAEPRFRDEFVIPHLHKLALVNNQQSVDSKRLDIATHLFEAYSALSCCFISEDLMVNHFLPGLKCLRIDMEHLSPEHEVILSSMIKECEQKVENKTVQEPQGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK", "length": 1208, "header": "tr|A0A8V0YC62-1|A0A8V0YC62_CHICK Isoform 1 of LisH domain and HEAT repeat-containing protein KIAA1468 OS=Gallus gallus OX=9031 GN=KIAA1468 PE=1 SV=1 CANONICAL=A0A8V0YC62-1" }, "locus": { "chromosome": "2", "start_pos": 68057010, "end_pos": 67983274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028763.1", "url": "https://www.ensembl.org/id/ENSGALT00010028763.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016548.1", "url": "https://www.ensembl.org/id/ENSGALP00010016548.1" } ] } }, { "isoform_ac": "A0A8V0YDD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62/entry#A0A8V0YDD1-1", "sequence": { "sequence": "MAAAGGGSSVNPFLSDSEEDEPEEARPGGGGGSSSSTEPGGPAYPARRREEVAAVGSPEELPGLRAAGDAAAGAGGGAAAGEPPRVSMDAMAAQLLRDQFLLTALELHTELLESGRELPRLRDFFSNPGNFERQSGTPPAGGGLGGSVLGGAGGREPGSGQLNRAGSISTLDSLDFARYSDDGNRETDERVAVLEFELRKAKETIQALRANLTQAAENEVPLQERKNYKSSPEIQEPIRPLEKRALNFLVNEFLLKNSYKLTSITFSDENHDQDFELWDDVGLNIPKPPDLLQLYRDFGNHHVTARDVVDVSVGVDDDELEATTPILGTVPVFETTPQSIEQCLIVQKLEDQISVLNNEKWSLMEQIQRLESEIDFLKNENFAVSTVYGVAPHPSLKQVPHTDSEDNGRYLDIKSSENDSKHGNTEEKSLSSSAEHDTRTSKDDTLNSVPCKDPEKVSSCAPSKKTAVHFDKPNRKLSPAFHQALLSFCRMSADSRLGSEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQFHLIPTLLSKIEKLLREGEHGLDEHKLHTYLSALQSLIPSLFALVLQNAPFTSKAKLQGEVPQIEVTRFPRPASPLQDVAIIIGSREQLAVLLQLYNHQLEHEGTTGWETLLWVVNQLLPQLIEIVGKINVASTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSTAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTMLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFEFSEDSDNSCFWDHHGNCYTKRASGKGKNAASIFPGGPSISRPTFSSYRNHKNIWKSWT", "length": 1039, "header": "tr|A0A8V0YDD1-1|A0A8V0YC62_CHICK Computationally mapped isoform of LisH domain and HEAT repeat-containing protein KIAA1468 OS=Gallus gallus OX=9031 GN=KIAA1468 PE=1 SV=1 CANONICAL=A0A8V0YC62-1" }, "locus": { "chromosome": "2", "start_pos": 68057010, "end_pos": 67991983, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028706.1", "url": "https://www.ensembl.org/id/ENSGALT00010028706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016509.1", "url": "https://www.ensembl.org/id/ENSGALP00010016509.1" } ] } }, { "isoform_ac": "A0A8V0YFL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62/entry#A0A8V0YFL2-1", "sequence": { "sequence": "MDAMAAQLLRDQFLLTALELHTELLESGRELPRLRDFFSNPGNFERQSGTPPAGGGLGGSVLGGAGGREPGSGQLNRAGSISTLDSLDFARYSDDGNRETDERVAVLEFELRKAKETIQALRANLTQAAENEVPLQERKNYKSSPEIQEPIRPLEKRALNFLVNEFLLKNSYKLTSITFSDENHDQDFELWDDVGLNIPKPPDLLQLYRDFGNHHVTARDVVDVSVGVDDDELEATTPILGTVPVFETTPQSIEQCLIVQKLEDQISVLNNEKWSLMEQIQRLESEIDFLKNENFAVSTVYGVAPHPSLKQVPHTDSEDNGRYLDIKSSENDSKHGNTEEKSLSSSAEHDTRTSKDDTLNSVPCKDPEKVSSCAPSKKTAVHFDKPNRKLSPAFHQALLSFCRMSADSRLGSEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQFHLIPTLLSKIEKLLREGEHGLDEHKLHTYLSALQSLIPSLFALVLQNAPFTSKAKLQGEVPQIEVTRFPRPASPLQDVAIIIGSREQLAVLLQLYNHQLEHEGTTGWETLLWVVNQLLPQLIEIVGKINVASTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSTAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTMLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFELTLRGMSEALVDKRVAPALVTLSSDPEFSVRIATIPAFGTIMETVTQRELLERVKMQLASFLEDPQYQDQHSLHTEIIKTFGRVGPNAEPRFRDEFVIPHLHKLALVNNQQSVDSKRLDIATHLFEAYSALSCCFISEDLMVNHFLPGLKCLRIDMEHLSPEHEVILSSMIKECEQKVENKTVQEPQGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK", "length": 1121, "header": "tr|A0A8V0YFL2-1|A0A8V0YC62_CHICK Computationally mapped isoform of LisH domain and HEAT repeat-containing protein KIAA1468 OS=Gallus gallus OX=9031 GN=KIAA1468 PE=1 SV=1 CANONICAL=A0A8V0YC62-1" }, "locus": { "chromosome": "2", "start_pos": 68056749, "end_pos": 67983274, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028719.1", "url": "https://www.ensembl.org/id/ENSGALT00010028719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016521.1", "url": "https://www.ensembl.org/id/ENSGALP00010016521.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420907", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ARP7-1", "protein_name": "RAB11-binding protein RELCH", "gene_name": "Relch", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAMAPGGGGSGSGVNPFLSDSDEDDDEVAATEDQRAGLRLGAGVGLDPGSAGSLSPQDPMALGSSTRPGLPVEASAAPGALAGSGETPSRLSIDAIAAQLLRDQYLLTALELHTELLESGRELPRLRDYFSNPGNFERQSGTPPGVGAPGIPGASVVGGAGGREPSTTSGGGQLNRAGSISTLDSLDFARYSDDGNRETDERVAVLEFELRKAKETIQALRANLTKAAEHEVPLQERKNYKSSPEIQEPIKPLEKRALNFLVNEFLLKNNYKLTSITFSDENDDQDFELWDDVGLNIPKPPDLLQLYRDFGNHQVTGKDLVDVASGVDEDELEPLTPVLGNIPPTLDTPLPIENSLLVQKLEDKISLLNNEKWSLMEQIRRLESEMDILKTEHFTTPAVGDSVQPSLAWPSPKDSEDSKQSPVVNSSDQDIQKAKDVHLEIPDGADSFIPKEKSSDSFPTKEREELPPSSVSSKATLHFDQPNRKLSPAFHQALLSFCRMSADSRLGSEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQSHLIPTLLSKIEKLLRDGEHGLDEHKLHMYLSALQSLIPSLFALVLQNAPFSSKAKLHGEVPHIEVTRFPRPMSPLQDVSTIIGSREQLAVLLQLYDYQLEHEGTTGWESLLWVVNQLLPQLIEIVGKINVTSTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSSAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTLLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFELTLRGMSEALVDKRVAPALVTLSSDPEFSVRIATIPAFGTIMETVIQRELLERVKMQLASFLEDPQYQDQHSLHTEVIRTFGRVGPNAEPRFRDEFVIPHLHKLALVNNLQIVDSKRLDIATHLFEAYSALSCCFISEDLMVNHFLPGLRCLRTDMEHLSPEHEVILSSMIKECEQKVENKTVQEPPGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK", "length": 1218 }, "evidence": [ { "id": "A0A8V0YC62", "url": "https://omabrowser.org/oma/group/A0A8V0YC62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q148V7-1", "protein_name": "RAB11-binding protein RELCH", "gene_name": "Relch", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAMAPGGGGSGSGVNPFLSDSDEDDDEVAATEDRRAGLRLGAGVGLDPGSAGSLSPQDPMALGSSARPGLAVEMSAAPAALGGSGETPARLSIDAIAAQLLRDQYLLTALELHTELLESGRELPRLRDYFSNPGNFERQSGTPPGMGAPGIPGASIVGGAGGREPSTTSGGGQLNRAGSISTLDSLDFARYSDDGNRETDERVAVLEFELRKAKETIQALRANLTKAAEHEVPLQERKNYKSSPEIQEPIKPLEKRALNFLVNEFLLKNNYKLTSITFSDENDDQDFELWDDVGLNIPKPPDLLQLYRDFGNHQVTGKDLVDVASGVDEDELEALTPILGNVPPTLDTPLPIENTLLVQKLEDKISLLNNEKWSLMEQIRRLESEMDILKAEHFATPAVGDSVQPSLVWSSQKDSEDNRQSPAVNSSDQEKTKDVHLEIPDAADSFIPKENSSGSFPRKEREELPPSSVSNKTTLHFDQPNRKLSPAFHQALLSFCRMSADSRLGSEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQSHLIPTLLNKIEKLLREGEHGLDEHKLHMYLSALQSLIPSLFALVLQNAPFSSKAKLHGEVPHIEVTRFPRPMSPLQDVSTIIGSREQLAVLLQLYDYQLEHEGTTGWESLLWVVNQLLPQLIEIVGKINVTSTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSSAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTLLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFELLVKGVNETLVAQRVVPALITLSSDPEISVRIATIPAFGTIMETVIQRELLERVKMQLASFLEDPQYQDQHSLHTEVIRTFGRVGPNAEPRFRDEFVIPHLHKLALVNNLQIVDSKKLDIATHLFEAYSALSCCFISEDLMVNHFLPGLRCLRTDMEHLSPEHEVILSSMIKECEQKVENKTVQEPPGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK", "length": 1216 }, "evidence": [ { "id": "A0A8V0YC62", "url": "https://omabrowser.org/oma/group/A0A8V0YC62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54H18-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVAKEDIAKFLLGKGYYLTALEFYQELLEDDGTELESLKQYLFGNKNDNNKNDNNNGNGSDFDPIKSIKEKNKKENNNNNNNNENESMKLKDDKISLLEYELRQCKDDLYRVKAQYNLVTTNGKSSSSSSSSTQPSSTTTSSSSSSMNGVALSISEDDKDTLKELSKERIKQHELRILNYLVKSYLKKNNYTLTAVSMSEEIEENCQHWSDVIGSKGTPEPPSILTMYRYFFENGDAGIQGALSRSMTEITKLKKDLYETESQWRESKKKLQQFQKEKDDLILKNKEFENKIEEFSRRGLLSPLRSSQTLQQQQQTDLISTSNNIASPPTHQNGKKLSPIITSSNSTINGNVVNNGIDITNLSVMRKTFRNLIEKRRQTVAFRIVSNMDDESEISVRIAEEVDKIRTLDSDNQSIVKIVADSLPNIVPGVLINKREELIPLILVVISNHPDETVRFSLTKLLFNLIKKPNEVQRHVIMRGCMALASFIGPQRTETEILSQCWEQLSEKYPERRVLVADSCGCLSQFASADLRLSLILSILQQLGEDKSSLVRESVAKNFALLVNFFDSPDKYNQIEESFKKLLYDTDVEVSIATRFHFLPSLANWADLLESLNSKLTNFLLTEMLSILIKYSAQKDEFKIPEQDTFKLDQLLQCFIDLIPRIHQSVISSSIFINEKDALQIENEYNKQEALYQFQINNQNQNNNNNSTTTTTTTTTSTNTNNSSSSSNSTTNNNNNNKDNKTIGSSTIINSAIRISILGNNEISKLQSQFENYLMTTVGNEVSSSGWPSLEWISNDFINKFIRIISCIPFYNSTVITGFSKALNLFCKTFGTVFTKRIIKNAFNKEFQKESNNNSNSSSSSNNNNTTSIKKNRLLSIYTTGALQTLESSEFITFLKDLIVQISMEERGWLHSDIPALVKCIELLCGNVFDKKKDVCDSLCDLTANPSNQVRSCILNLLNFIIPVFKPEQIGQSVVPSLITMSTDPDRTVRFVCLGTLSIAVSFINDDTVIEKVAGAIDRILEDKNHMVELEFVNSMSRIIPTVKPRFRDSFILPRIIDLTRKNNHNPSNQQRKEMSQCLYECIRSYVSITTVPRELISEQVLPMLKLLLNDALLHDPTFKSMVQSLVNDLESSIKEDFRNSIGAKKNTSTSSNKIDPPNKWGLSWKPNK", "length": 1169 }, "evidence": [ { "id": "A0A8V0YC62", "url": "https://omabrowser.org/oma/group/A0A8V0YC62/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9P260-1", "protein_name": "RAB11-binding protein RELCH", "gene_name": "RELCH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAMAPGGSGSGGGVNPFLSDSDEDDDEVAATEERRAVLRLGAGSGLDPGSAGSLSPQDPVALGSSARPGLPGEASAAAVALGGTGETPARLSIDAIAAQLLRDQYLLTALELHTELLESGRELPRLRDYFSNPGNFERQSGTPPGMGAPGVPGAAGVGGAGGREPSTASGGGQLNRAGSISTLDSLDFARYSDDGNRETDEKVAVLEFELRKAKETIQALRANLTKAAEHEVPLQERKNYKSSPEIQEPIKPLEKRALNFLVNEFLLKNNYKLTSITFSDENDDQDFELWDDVGLNIPKPPDLLQLYRDFGNHQVTGKDLVDVASGVEEDELEALTPIISNLPPTLETPQPAENSMLVQKLEDKISLLNSEKWSLMEQIRRLKSEMDFLKNEHFAIPAVCDSVQPPLDQLPHKDSEDSGQHPDVNSSDKGKNTDIHLSISDEADSTIPKENSPNSFPRREREGMPPSSLSSKKTVHFDKPNRKLSPAFHQALLSFCRMSADSRLGYEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLHILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAESCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYHQGFELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQSHLILTLLNKIEKLLREGEHGLDEHKLHMYLSALQSLIPSLFALVLQNAPFSSKAKLHGEVPQIEVTRFPRPMSPLQDVSTIIGSREQLAVLLQLYDYQLEQEGTTGWESLLWVVNQLLPQLIEIVGKINVTSTACVHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSSAGNGVLTKATVPIYATGVLTCYIQEEDRKLLVGFLEDVMTLLSLSHAPLDSLKASFVELGANPAYHELLLTVLWYGVVHTSALVRCTAARMFELTLRGMSEALVDKRVAPALVTLSSDPEFSVRIATIPAFGTIMETVIQRELLERVKMQLASFLEDPQYQDQHSLHTEIIKTFGRVGPNAEPRFRDEFVIPHLHKLALVNNLQIVDSKRLDIATHLFEAYSALSCCFISEDLMVNHFLPGLRCLRTDMEHLSPEHEVILSSMIKECEQKVENKTVQEPQGSMSIAASLVSEDTKTKFLNKMGQLTTSGAMLANVFQRKK", "length": 1216 }, "evidence": [ { "id": "A0A8V0YC62", "url": "https://omabrowser.org/oma/group/A0A8V0YC62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular cholesterol transport", "id": "GO:0032367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032367", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1161, "end_pos": 1163 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 418, "end_pos": 420 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YC60-1", "uniprot_ac": "A0A8V0YC60", "uniprot_id": "A0A8V0YC60_CHICK", "mass": { "chemical_mass": 152878.0, "monoisotopic_mass": 152878.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YC60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC60/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YC81-1", "uniprot_ac": "A0A8V0YC81", "uniprot_id": "A0A8V0YC81_CHICK", "mass": { "chemical_mass": 177210.0, "monoisotopic_mass": 177210.0 }, "refseq": { "ac": "XP_025010326", "name": "leucine-rich repeat and IQ domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010326" }, "gene_names": [ { "name": "LRRIQ1", "type": "recommended", "evidence": [ { "id": "A0A8V0YC81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81" } ] }, { "name": "LRRIQ1", "type": "synonym", "evidence": [ { "id": "XP_025010326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010326" } ] } ], "protein_names": [ { "name": "Leucine rich repeats and IQ motif containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0YC81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and IQ domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025010326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010326" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025010326.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010326" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81", "locus": {} } ], "crossref": [ { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417882", "url": "https://www.ncbi.nlm.nih.gov/gene/417882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417882", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHRYAHE", "url": "https://omabrowser.org/oma/group/KHRYAHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YC81", "url": "https://www.orthodb.org/?gene=A0A8V0YC81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGX2", "url": "https://www.orthodb.org/?gene=A0A8V0YGX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46652:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46652:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025010326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YC81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESRMSEDTEGIEKEIESELSRISVSSFEADGPDTEVPEESVSDTESISDDLPESVLSYLNFIKNRNQDAEKVILQDLDDEETTSNIHEVVPCYALDNLAELSSECNEDPEQFKKRLLFEIENEDLKVPTTPSCNSQSSSEVVTDDLFLTADIEMNMSLTYHEVEEKCRQEFQQWEKRQSEIEDDKRKKWKAEREAQEKQNEEEHARRVQHLEKFEAERMELELLHKKQQALMEDELQKEKKAWRDKMMQHEELIMKLQLQMEQEKRAFEEQEAKECKHLTEQRNTAAVKIQARFRAYLVHKEYAPILKQWKDEIKKKKKIQEEIEREMKVREEKMRRRMEERMQNKKEEKKRQEELERQKYLEQVGRRKEYEKKKASLRLEREKQLKIREEQRKLREKIDKAMITENGESNKENIKENKLTENKDVIRDEKKELNKQVEEQEEQTDIMGETNSGMISTERKLTPTLTVLVSEKEDSSRVNNENICINLITYVEENYSQTKELNKEASIIHTLKDESVDFGANYRVESKSNDTCSSQSNAQSNADDQDQFSQSETIEKTVFPMEDANEEVIKNWDTVQEVSKCSNSLILPNDIEKKRTNWMTTCESWSKVYEENQRKIPNIKKRSRKTSVSKMPPLSIQKIIHSGPWSTLQQITTLTLEDLPACSLSTLSQCSNLQVLTLRRCGLVALEGLSSCKDLKYINVEENNIQVIDCENLENLCILILNKNHLSSISGLDGCINLQNLELSYNRITRIGGLESLKNLQQLTVDHNQLISTKGLCEVPTLIHLDCSFNHLTQVEGIESCGLLQILKLHSNNLQEFPRLENHVLLRELYLDDNSISSVRMLSLYWLPLLQILLLSHNSLTELVPLNSFVSLEKLDIKNNCLSDLKSVIACLSGCINLRELSLTGNPLLQERNWRPSLCKILSRLQFLDGENVHYNTLPTTERIEASESRTFLELCQVQIEENVLLKKKVVEEGIAASMDAVQRQCWYFNQLMKLSIKHRCAHEYGELSTTDRDRPEALQNHLKQASTGCLQENNLFIMGVTENKQVLLDPSERWITTGRFQSTFFNSSISVHQKENKEDHRMKQKTTESCINCNGESNSNKNISAQLTLQQSVVESNMGRDSENNTERLRMAASVIQSHWRKYRSRRKTDCTKTRNDHFGEASRQKHEAATVIQASWKGFLLRRKLTSALAAVKSDEVDDNYEEINVDDFVSHEAAIGNEWLTPDSTHFPSKTLLISNQLHWTKYAGPSDTSKHSDNLQLPPQAPWQCLDRPHSTENTRYHRSSEKGTMSQNSDLKEKKKFSSRSDKEEKISEEWGFKDISTAQLMLKRAHKMKPRQYSNKSTDPAVRLALFKKNENKHLCVKPPKIQSVNAGYFEGEKEEFSQLDTSLDEKLQRRKDFTYQWLYTQHSDYETSSSKNMKGCCFLPELNHVSCNSGQVQPVASPVSREDTELDLVSLASGSALTVNREKNKQPHRHSARSSKKNVSTPEKSHFGPSCRERISFRDHPLQFSGGWGTGKKRQKVKNIS", "length": 1530, "header": "tr|A0A8V0YC81-1|A0A8V0YC81_CHICK Isoform 1 of Leucine rich repeats and IQ motif containing 1 OS=Gallus gallus OX=9031 GN=LRRIQ1 PE=4 SV=1 CANONICAL=A0A8V0YC81-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81/entry#A0A8V0YC81-1", "sequence": { "sequence": "MESRMSEDTEGIEKEIESELSRISVSSFEADGPDTEVPEESVSDTESISDDLPESVLSYLNFIKNRNQDAEKVILQDLDDEETTSNIHEVVPCYALDNLAELSSECNEDPEQFKKRLLFEIENEDLKVPTTPSCNSQSSSEVVTDDLFLTADIEMNMSLTYHEVEEKCRQEFQQWEKRQSEIEDDKRKKWKAEREAQEKQNEEEHARRVQHLEKFEAERMELELLHKKQQALMEDELQKEKKAWRDKMMQHEELIMKLQLQMEQEKRAFEEQEAKECKHLTEQRNTAAVKIQARFRAYLVHKEYAPILKQWKDEIKKKKKIQEEIEREMKVREEKMRRRMEERMQNKKEEKKRQEELERQKYLEQVGRRKEYEKKKASLRLEREKQLKIREEQRKLREKIDKAMITENGESNKENIKENKLTENKDVIRDEKKELNKQVEEQEEQTDIMGETNSGMISTERKLTPTLTVLVSEKEDSSRVNNENICINLITYVEENYSQTKELNKEASIIHTLKDESVDFGANYRVESKSNDTCSSQSNAQSNADDQDQFSQSETIEKTVFPMEDANEEVIKNWDTVQEVSKCSNSLILPNDIEKKRTNWMTTCESWSKVYEENQRKIPNIKKRSRKTSVSKMPPLSIQKIIHSGPWSTLQQITTLTLEDLPACSLSTLSQCSNLQVLTLRRCGLVALEGLSSCKDLKYINVEENNIQVIDCENLENLCILILNKNHLSSISGLDGCINLQNLELSYNRITRIGGLESLKNLQQLTVDHNQLISTKGLCEVPTLIHLDCSFNHLTQVEGIESCGLLQILKLHSNNLQEFPRLENHVLLRELYLDDNSISSVRMLSLYWLPLLQILLLSHNSLTELVPLNSFVSLEKLDIKNNCLSDLKSVIACLSGCINLRELSLTGNPLLQERNWRPSLCKILSRLQFLDGENVHYNTLPTTERIEASESRTFLELCQVQIEENVLLKKKVVEEGIAASMDAVQRQCWYFNQLMKLSIKHRCAHEYGELSTTDRDRPEALQNHLKQASTGCLQENNLFIMGVTENKQVLLDPSERWITTGRFQSTFFNSSISVHQKENKEDHRMKQKTTESCINCNGESNSNKNISAQLTLQQSVVESNMGRDSENNTERLRMAASVIQSHWRKYRSRRKTDCTKTRNDHFGEASRQKHEAATVIQASWKGFLLRRKLTSALAAVKSDEVDDNYEEINVDDFVSHEAAIGNEWLTPDSTHFPSKTLLISNQLHWTKYAGPSDTSKHSDNLQLPPQAPWQCLDRPHSTENTRYHRSSEKGTMSQNSDLKEKKKFSSRSDKEEKISEEWGFKDISTAQLMLKRAHKMKPRQYSNKSTDPAVRLALFKKNENKHLCVKPPKIQSVNAGYFEGEKEEFSQLDTSLDEKLQRRKDFTYQWLYTQHSDYETSSSKNMKGCCFLPELNHVSCNSGQVQPVASPVSREDTELDLVSLASGSALTVNREKNKQPHRHSARSSKKNVSTPEKSHFGPSCRERISFRDHPLQFSGGWGTGKKRQKVKNIS", "length": 1530, "header": "tr|A0A8V0YC81-1|A0A8V0YC81_CHICK Isoform 1 of Leucine rich repeats and IQ motif containing 1 OS=Gallus gallus OX=9031 GN=LRRIQ1 PE=4 SV=1 CANONICAL=A0A8V0YC81-1" }, "locus": { "chromosome": "1", "start_pos": 41902741, "end_pos": 41804331, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026756.1", "url": "https://www.ensembl.org/id/ENSGALT00010026756.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015257.1", "url": "https://www.ensembl.org/id/ENSGALP00010015257.1" } ] } }, { "isoform_ac": "A0A8V0YGX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81/entry#A0A8V0YGX2-1", "sequence": { "sequence": "MESRMSEDTEGIEKEIESELSRISVSSFEADGPDTEVPEESVSDTESISDDLPESVLSYLNFIKNRNQDAEKVILQDLDDEETTSNIHEVVPCYALDNLAELSSECNEDPEQFKKRLLFEIENEDLKVPTTPSCNSQSSSEVVTDDLFLTADIEMNMSLTYHEVEEKCRQEFQQWEKRQSEIEDDKRKKWKAEREAQEKQNEEEHARRVQHLEKFEAERMELELLHKKQQALMEDELQKEKKAWRDKMMQHEELIMKLQLQMEQEKRAFEEQEAKECKHLTEQRNTAAVKIQARFRAYLVHKEYAPILKQWKDEIKKKKKIQEEIEREMKVREEKMRRRMEERMQNKKEEKKRQEELERQKYLEQVGRRKEYEKKKASLRLEREKQLKIREEQRKLREKIDKAMITENGESNKENIKENKLTENKDVIRDEKKELNKQVEEQEEQTDIMGETNSGMISTERKLTPTLTVLVSEKEDSSRVNNENICINLITYVEENYSQTKELNKEASIIHTLKDESVDFGANYRVESKSNDTCSSQSNAQSNADDQDQFSQSETIEKTVFPMEDANEEVIKNWDTVQEVSKCSNSLILPNDIEKKRTNWMTTCESWSKVYEENQRKIPNIKKRSRKTSVSKMPPLSIQKIIHSGPWSTLQQITTLTLEDLPACSLSTLSQCSNLQVLTLRRCGLVALEGLSSCKDLKYINVEENNIQVIDCENLENLCILILNKNHLSSISGLDGCINLQNLELSYNRITRIGGLESLKNLQQLTVDHNQLISTKGLCEVPTLIHLDCSFNHLTQVEGIESCGLLQILKLHSNNLQEFPRLENHVLLRELYLDDNSISSVRMLSLYWLPLLQILLLSHNSLTELVPLNSFVSLEKLDIKNNCLSDLKSVIACLSGCINLRELSLTGNPLLQERNWRPSLCKILSRLQFLDGENVHYNTLPTTERIEASESRTFLELCQVQIEENVLLKKKVVEEGIAASMDAVQRQCWYFNQLMKLSIKHRCAHEYGELSTTDRDRPEALQNHLKQASTGCLQENNLFIMGVTENKQVLLDPSERWITTGRFQSTFFNSSISVHQKENKEDHRMKQKTTESCINCNGESNSNKNISAQLTLQQSVVESNMGRDSENNTERLRMAASVIQSHWRKYRSRRKTDCTKTRNDHFGEASRQKHEAATVIQASWKGFLLRRKLTSALAAVKSDEVDDNYEEINVDDFVSHEAAIGNEWLTPDSTHFPSKTLLISNQLHWTKYAGPSDTSKHSDNLQLPPQAPWQCLDRPHSTENTRYHRSSEKGTMSQNSDLKEKKKFSSRSDKEEKISEEWGFKDISTAQLMLKRAHKMKPRQYSNKSTGEKEEFSQLDTSLDEKLQRRKDFTYQWLYTQHSDYETSSSKNMKGCCFLPELNHVSCNSGQVQPVASPVSREDTELDLVSLASGSALTVNREKNKQPHRHSARSSKKNVSTPEKSHFGPSCRERISFRDHPLQFSGGWGTGKKRQKVKNIS", "length": 1497, "header": "tr|A0A8V0YGX2-1|A0A8V0YC81_CHICK Computationally mapped isoform of Leucine rich repeats and IQ motif containing 1 OS=Gallus gallus OX=9031 GN=LRRIQ1 PE=4 SV=1 CANONICAL=A0A8V0YC81-1" }, "locus": { "chromosome": "1", "start_pos": 41902741, "end_pos": 41804331, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026759.1", "url": "https://www.ensembl.org/id/ENSGALT00010026759.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015260.1", "url": "https://www.ensembl.org/id/ENSGALP00010015260.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417882", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZJI9-1", "protein_name": "Leucine-rich repeats and IQ motif containing 1", "gene_name": "Lrriq1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDSDDSDAKLQEEIEAELDKISISSLENDEVENDSESETQSDDSDTDVLELPESVLHYFSVIKNKSKTAEELILQDLEDTDVFSCSYGAVSDSHMHLRTGSASPESKANSEQLMKILSVIDKEEFMRSLAPSAKRVSVPEPITLDISMDEYVLPDEADLSFGYFEVEERCRKSFEAWQDKQQELEVKDKAILEAQSDREKQSFQEEDEKRQCWIRQFEVEKKKLENLHKQNQDKMNDELHKEEKIWKEKYRQHEERIRNLHLQMEEERTRLRELREKEKARLFKLQHDAAVKIQANYRAWVTYRKYSPIIREQIEKKKRKAQELKEKEAKIRQKEEERRRRIEEEQRIKEERKKKMLEERRRREKEYEEKKSILRQEREEQKSKEKRLREHAHSPLIITCALKKGECHGKQQAIVQMSKSKGSIDKESVGSDSKKQEDTCLVHQLNKRENMHKQIALKESTGIKLKPSQDILAELKLNEKIESLPKLKMNENFSNNQCSGSEQSADQEINSENRDLKSDLENSDLTENVNEQCPGQELNSETQMEGWVEHAPKENVGQETQKLFGFREEMSEEDSNEAPEIIEENHERMTEEIEIKEMTEQDGSSCEENNSSPISIQKNLPPLIPDNPEPVERSVTLAEDEETDLKSERIEEIPEGVLACDASTIKSNASVLTEGKADLQDSFSGKLAPSEEAGSHSACYLLVTDEGEDSPKSEIKETLEEGKQTESEGVGVLACSSSQITVLSSIEEKRLAWVRSFKPWTEIFEQNQLKKIVKKRRLVKCSPNTMPALDPSAILQLGPWKTLQQVTAITFQDLPSCSLSILAECSNLQLLSLQRCGLTSLQGLSHCTNLKYIDAQENHIETISCENLENLSVVLLNKNLLTSIHGFDGCTNIQILELSYNKITRISGLESLKYLQQLIVDHNQLISTKGLCEVPTIVYLDCSHNHLTDVDGIGNCGLLQIVKLQGNYLREPPSLRNHVLLRELHLDDNSISSVEGLSSCWLPLLQILSISQNSLATIVPLFHFVSLEKLDVSNNCLSDLTNVMCWFNACYSLGELCLIGNPVLQEVNWRHSILQALPALRVLNGDMLNSSSNVHIEEYYHQDLRYFLALCQYQLQEFNLLFEKSITQRGDILNMRAADRLSQYYKDLMRLSNECRLAHEQWDVNITKRSAVETKKDHPAFPNSDSTLHNRTFHPQANDCKAHSPAISTILLDTASKPSTSNCEELKGRDQEKLMEQKSKHSSISSLSTMKASIIEMKMADSPMSTHHSDEKCEPSKAAMIIQAQWRSYIARRQIDYSEKPCPTTASEPLCNSFINDQMTSNEEGRKPIMNIQEQREKAALCIQAVWKGFILRKKLVTAIEAIKDEESGEEYEEIDLEDFEFDEDALEKDWPALDSTSFPSQTLPLSKQLPWPKNTRTLRHDETSPPVPAHPAQAWLCNERENLLSSEHTQFSSSRSESGTLSWTPESKSSRKSLLQSEKEEKISEEWGFKDISTAQQMLKRAKKMKSRKLRKKLEPSVRLALFKKNKNKLSVTKSSKKSQLRRDNYFADEEEEAASKATAAKEKLERSKEYTYQWLHTQVGFPEATSSRNVKCNHFLPELDPDVLNGGRVQLVARLVSREDTDLDLFSMTSASTLSVNKEKKSQTHRYSTGSSSGSNKGIIAPMITHTRPSIKERISFRDNPVQLSGGWGSGKRKVKSST", "length": 1702 }, "evidence": [ { "id": "A0A8V0YC81", "url": "https://omabrowser.org/oma/group/A0A8V0YC81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B933-1", "protein_name": "Leucine rich repeats and IQ motif containing 1", "gene_name": "LRRIQ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMEGNDDDDIKLSEEIEAELDRISISSLEKYGFDSDSKSETQSDNSDTDSDELPESVLHCINIIKNKSKTAEELILQDLEDTDVLSCGYGGVSNNHMHLRIELPTECKENPEQLIKMLSEIEKEEFLRSRTHCGSPDLVLESDLCDLPVDEHVLPDDADINFGYREVEERCRQSFEAWQDKQKELEDQEKETLKVERDKEEKQFQEEEEKRHCWMKQFEVEKKKLENIQKQEQDKMNDELHKEEKIWKERFKQHADFIRNLHLQMEEERTKFKDLQEKEKMRLSKLQHNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKKKAQEWKEKEAKIRQIEEKRKRLEEKQRIEEEIEKQMQEGRKRREKEYMGKKNILRQEREQLLKMEKLILREATRKQLIISRALKKGEYNAKHLPIEDTSKNKDVGAKRLGDGKLKMWEDASPWLAEESDKRKNVDRELVLKESVQVQLKESMSSQAILAVFKVEEKKKNLAVQCSEEFVKQKRNYENRDQKNQLENLHLKEDVREQFQSQELQSQVQKEEVLKPSINETMRQETQIILGNNQEIDEVKDNESQKIVDDNQQNKMQKVEKEISGQLGTLYEENNIKEISVISMKQKQVPLKLEKSEHIGENTLLQEEEIDLKSKEAEENPNGSALNSDLVFNTNDAVINVEGKINKQNYIVDAPCEDLGGYNAKNCLVFKEVNSLKSQIQEIPEECHENTAECENIVACSIEPTLLSSIEEKRLAWITSFKPWFEIFKQNQQKKIVKRRRIIKCPVNTMPPLNPLEILRCGPWDTLQQVATITFQDLPGCSLSTLAECPNLQFLSLRRCGLTSLHSLSNCKRLKYIDAQENHIETINCENLENLCIVLLNKNQLTSLHGLDGCTNIQSLELSHNKITRIGGLESLKNLQQLIVDHNQLISTTGLCDTPTLMYLDCSHNHLTEVEGIEQCGLLQILKLQGNYLSELPFLGNHVLLRELHLDDNSISTVETFSSYWLPLLQILTISQNSLTKIAPLFHFVSLEKLDVSNNCLSDLTSAIKWFDACFSLHELSLTGNPLLQEINWRHSLLKILPALRILNGEMLTSCTERHTEGHHQLELEHFLEHCQSQIREFNLLSEKYITGDRNIFTLDVAQNLCYYFKKLMTLSNECRCVHEHGDVSMTRRGESEAQQNHLPPTHSDSKQQNRVLYSSANEYKLNSPDISEKWMDSGSSHSSSTNPSLCEDTKERNQEEIVDQKREDSKTSSFPSKRIPFIETVRTRFLLENCQNTEHHEKIMAAMVIQAYWRGYIVRRQIHFSAKLHPATIGPLTSKPNSCIENQTILKKEKVKNTVNIQEQKEKAAILIQAVWKGFLLRKKLTTALEAIKNEESEEEYEEIDLEDFTFDEAALEKEWLALDSARFPSQTLLLPNQLHWPKFSGILKYDDTSLNLPSHPAQAWLCNEKENVLSSEHTQFNSRSENRTLSRLPEAKTSRKSLLKSEKEEKISEEWGFKDISTAQQMLKRAQKMKSKKLRKKLDPTVRLALFRNNENKVSVIKPPEKAQPQRDGFFEDKEEEFMYKDTTANEKLERSKEYTYQWLHTQVGVLETTGSRNMKCKHFLPELDPDVRNGGRVQLVARLVSREDTDLDLFSMTSGSALSVKTEKKTLAHRHSAGSSSKLWFPSELISKSQMN", "length": 1667 }, "evidence": [ { "id": "A0A8V0YC81", "url": "https://omabrowser.org/oma/group/A0A8V0YC81/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0P5X1-1", "protein_name": "Leucine-rich repeat- and IQ domain-containing protein 1", "gene_name": "Lrriq1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSDDSEAKLREEIEAELDKISISSLENDEVENDSVSDTQSDSSDTDLLELPESVLHYINVIKNKSKTAEELILQDVEDTDIFSDYKKGCNHGTVTDSHMHLRTGSLPESKANAEQLMKILSVIEKEEFMRSLAPSARCVSVREIITPDTPMDEYILPDEADLSFGYFEVEERCRKSFEAWQDKQQELEEKDKETLEAQNEREKRTFQEEDEKRQCWMRQFEVEKKHLEDLQKQDQDKMNDELHKEEKIWKEKYRQHEEHIRNLHLKMEEERTRLSELQEKEKARLFKLRYDAAVKIQATYRASVTYRKYSPIIKEQMEKKRRRAQELKEKEAKIRQKEEEKRRRLEEEQRVEEEKKKKMLEERRRREREYEEKKSILRQEREEQRSKEVIRLREHAHSPLIITCALKKGDCHGKQQAIAHVPKGKGTIAKESVDSNSKKQEDACLAQQLNKRENTHVQQLAMKKSTGIKLKPNQAILVELKMNEKNESLPKLKINENLSKNQCSEQPSDQEFNAENVDQKNELENSNLKESVNEQYPWQGLESDTQTEEHVEHVREEKVGQETEKLFGFNQEVSAEDSKQAQGVMEETREGLAEEIEIKEMTQQGGPSDENNSSPISMQKSLPSLTPDNPEPVERSVTLEEDQETDLKSERIEEIPEEGVLSCDAAVINADASVHTEGEADLQDSASGKLAPSEEAGSHSANNLLATEEVEDSPKSEIQEALEKGQQTKAEADGVLTCSVSQLTVLSSVEERRLAWVKTFKPWAEIFEQNQHKKIVKKRRLVKCPPNTMPPLDPSAILQYGPWKSLKQVPVITFQGLPGCSLSTLAECSNLQILSLRRCGLTSLQGLSHCTRLKYIDAQENHIEAISCENLENLSVVLLNNNLLTSIHGFDGCTNLQSLELSHNKITRISGLESLKYLQELTVDHNQLISTKGLCEAPTIVYLDCSHNHLTGIDGIGNCGLLQIIKLQGNYLREPPSLRNHVLLRELHLDDNSISSVEGLSSCWLPLLQYLSISQNSLATIVPLFHLVSLEKLDVSNNCLSDLTNVMCWFNACYSLRELCLTGNPVLQEINWRDSILKTLPALRVLNGDMLNSYANDRIEEHYHQDLRCLLALCQYQLQEFNLLPEKYITQKRDILTLHAVDRLSQYYKDLMKLSHECRRAHEQGDVNTTERSAAETNKNHPDFSNTDSALQNKTLHAQTNSCEADSPATSPNPLDTVFRPSTSHCEELRGRNQEKLMAHKSEQSRISSRSNSRASFIEMKMADSPMSNHHNAERSSPTKAAMVIQAQWRSYIAHRQINCSAEMHPTTTEPLQDPLINNQTTSNEERRKTNMDIQEQREKAALHIQAVWKGFILRKKLATARKAIKDEESGEEYEEIDLEDFEFDEDALEKDWPALDSTGFPSQTLPLSNQLPWPKNSRTLRHDETSPTIPVRPAQAWLCNEKENVMSSEYTQLSSRSESGILSWTPDSKTSRKNLLQSEKEEKISEEWGFKDISTAQQMLKRAKKMKSKKLRKKLEPSVRLALFKKAKNKVSVTKSSKKTQLRRDNYFEAHISSQDEEEEAVSKATAAKEKLERSQEYTYQWLHTQVGFPEATSSRNLKCNHFLPELDPDVLNGGRVQLVARLVSREDTDLDLFSMTSASALSVNKDKKSQTHRYSTGSSSKLWFPSELI", "length": 1673 }, "evidence": [ { "id": "A0A8V0YC81", "url": "https://omabrowser.org/oma/group/A0A8V0YC81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JM4-4", "protein_name": "Leucine-rich repeat- and IQ domain-containing protein 1", "gene_name": "LRRIQ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDDDAKLKAEIEAELDKLSISSLEKEDIESDAKSETQSDDSDTDSVELPESVLHCINIIKNRSKAVEELILQDLEDTDILSCSYGAVSNNHMHLRTGLSTEYEESSEQLIKILSEIEKEEFMRSKTDCATPDFVPEPSPHDLPMDEHVLPDDADINFGYCEVEEKCRQSFEAWQEKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDELYKEEKIWKEKFKQHEEYIRNLHLQMEEERTRFKDQQEKEKNSLLKQQNNAAVKIQAKYKAFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTILKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSDLKGNLKEQFPLQELKSDAQKEEKIMKHVINENTGQKTQIILGHNQEISEVKTNEEQKIIKDNQQKKIQKVEKEEIQEQNGLLYKDKDTLVISVKQRSLSLTSENSKDVRENVILQEKEIYSKSKEIEENPKDNAWNSGIVIFNTTDTMINIEGKRNDQDYVLGRHAPCEGLSNYNAESSMVSKEVNSLKSEIRNISEKCHENAPEPDSMTCCVSESTLLYSIEERRLAWIKSFKPWLEIFKQNQQKKIVRRKRPVKCPANMTPALDKLEILRCGPWDTLQQVTTVTFQDLPGCVLSTLAECTNLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECENLENLCVVLLNKNQLTSLHGLDGCTNIQCLELSYNKITRIGYSFFLEEKLVDNAGFCHHLGTSTSYLSLAQVWIPTGLCWSWIPITSLTKNSDCNFLISHLYWNCGLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTDVEGVENCGLLQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSLTKIVPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSLLKVLPALRILNGNILNSNSESRTEEHNQLGSAGFLALCQSQIREFNLLIENYITGKGDVFTLDTAENLCHYFKKLMILSTEYRHAHERGDVTITKKDESEAQKNHLAPTNSDSTLQNGVFYSCAREGEPDSPDIPEKWMDSVSSHSPLSKSATCENMEGRHQEILVCQKREDSKASSIPTIRIPFKEVVMTNSLLRNHQNIEPSEKIMAAVVIQSYWRGYLMRRQTHFSTRLHTAATEGLPNSSIKNQTILKKGKRENIVNIRKQREKAAILIQAVWKGFILRKKLTTALEAIKNEESDEEYREIDLEDFIFDEAALEEEWLALDSTRFPSQTLLLSNQLHWPKIPGNLKWDDTSFNLPSNPAQAWLCNDKENLSSSEHTQFNSRSENKTSSWTPESKTSRKSLLKSEKEKKISEEWGFKDISTAQQMLKRAQKMKSKKLKKKIDSTVRLALFKNNENKVSLPKSPKMVQPRRDGYFEGIEEDPIHKDTTANEKLERNREYTYQWLHTQVGVHETTSSRNMKCNHFLPELDPDVLNGGRVQLVARLVSREDTDLDLFSMTNGSALSVNREKKNQAHRHSAGSSSKLWFPSKLI", "length": 1722 }, "evidence": [ { "id": "A0A8V0YC81", "url": "https://omabrowser.org/oma/group/A0A8V0YC81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dynein complex binding", "id": "GO:0070840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1069, "end_pos": 1071, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1105, "end_pos": 1107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1127, "end_pos": 1129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1343, "end_pos": 1345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1487, "end_pos": 1489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1528, "end_pos": 1530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1069, "end_pos": 1071 }, { "start_pos": 1105, "end_pos": 1107 }, { "start_pos": 1127, "end_pos": 1129 }, { "start_pos": 1343, "end_pos": 1345 }, { "start_pos": 1487, "end_pos": 1489 }, { "start_pos": 1528, "end_pos": 1530 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 531, "end_pos": 533 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YC85-1", "uniprot_ac": "A0A8V0YC85", "uniprot_id": "A0A8V0YC85_CHICK", "mass": { "chemical_mass": 9793.0, "monoisotopic_mass": 9793.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0YC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC85/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0YC85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC85/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YC85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC85", "locus": {} } ], "crossref": [ { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46077", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46077", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46077:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46077:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YC85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YC85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LEEEVLETMAAAEAWTCPVCREARRDVAYATPCNHQFCLGCIQRWAMLKTSCPLCRTSFCLRPHIKYTTQLTDTTNKTALLKYIY", "length": 85, "header": "tr|A0A8V0YC85-1|A0A8V0YC85_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YC85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YC85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC85/entry#A0A8V0YC85-1", "sequence": { "sequence": "LEEEVLETMAAAEAWTCPVCREARRDVAYATPCNHQFCLGCIQRWAMLKTSCPLCRTSFCLRPHIKYTTQLTDTTNKTALLKYIY", "length": 85, "header": "tr|A0A8V0YC85-1|A0A8V0YC85_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YC85-1" }, "locus": { "chromosome": "1", "start_pos": 59238959, "end_pos": 59237059, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026765.1", "url": "https://www.ensembl.org/id/ENSGALT00010026765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015262.1", "url": "https://www.ensembl.org/id/ENSGALP00010015262.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0#function" }, { "database": "UniProtKB", "id": "ARBA00056020", "url": "https://www.uniprot.org/uniprotkb/ARBA00056020#function" }, { "database": "UniProtKB", "id": "A0A8V0YEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0", "locus": { "chromosome": "1", "start_pos": 45423525, "end_pos": 45490697, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011738", "url": "https://www.ensembl.org/id/ENSGALG00010011738" } ] } } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13237", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13237", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15743", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15743", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417908", "url": "https://www.ncbi.nlm.nih.gov/gene/417908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417908", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMSSCKF", "url": "https://omabrowser.org/oma/group/PMSSCKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCC0", "url": "https://www.orthodb.org/?gene=A0A8V0YCC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YEJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSAGGQEGEEIKKPPVAPKPKFVVGHKATPPPVAPKPDVVLSGVLQAARKTKPAIAPKPKVLKSSSIPEVKPPSCARKGTKSFEEHRGDSSQTLDHLNYKNEVSEGSTDNTAYILPMSSCKFECLHKLGNGENTCKTQIILEHFENLENIKVDEKTALSLGSSPSEKMANRNQVVVKASILEEKLKDVLTHGVFPNRSPVRHRYADRLYKGDGNSSTNDVKIEFMELVQSSSSEVANGRQQNTGSKLTEDEFQTSETCPSLNENHSSFSCLLNQEILENENVNSSSSFSGEMGMKIDTGKTSSETCSALSSKMLPIPKPRKPRAACLVRQDGIDSVGEGTKEPSSSENDSFGPAEHSFKKPAKINVLGQSVCYNNHTEALNPEKSEITQSIADRMHLRKEPADTEESTLQNLLPQLSHKTSDLVENVECPLDTDHNLSSSVDRMTDDASMPDTVDKRTSFIRCDALSMSLPKQIKLPVSQHLPAANSLHVSLQKVEDREAKIKDESSPKIVPKKPQRHSLPAAGVLKKAASAELVEKSSYTSSEDKSNSVLEGSHFSHSPAREQGALSSSDIPRRSSEKPVWKLPHPILPFSGNSESLKTASIAPSFSHVSAVTKPRAKSLSSVDMERTDKPCKDTQKKNSLKKFLNVKLSVCLMKSDFQKLLSKGSQSMDSSTANLSTGEGYGNGNSRHVASVGSERKAKSAKARSVEISSPALQKKRQRNRSQPEMRSNQRLESLDGHSLPGENLSQMHLNSVTSNCAPEYENLRHYEEIPEYENLPFAMGAGKNLCLEWQNSSRVEDPSSSLYEVEEPFQAASRRVRHGRSLEEHHDHPGMVIGDLQSDDEDIVNSSDEDDDTNSDSSKGEPDSQDQSKAAGKKTKVYHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLRELEERLSHWLEHQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNAGFASVVKDFEMSPRCASLALKHYLLKPVQRIPQYRLLLTDYLKNLLEESADYRDTQDALAVVIEVANHANDIMKQGDNFQKLMQIQYSLNGHHEIVQPGRIFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVKKPSQEAYQNELNIESVERSFILSASSATERDEWLEAISRSIEDYAKKRITFNPSKSLEEADTEKQEEASPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKHGLDYMKNQPARVCDHCFRELQKQDNQCSPKTGSPVNHKSPSSALSTVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLHRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVSEVRDENSESRVFHLLHKNTLFYIFKADDPHSAQKWIEAFQEGTVL", "length": 1439, "header": "tr|A0A8V0YCC0-1|A0A8V0YCC0_CHICK Isoform 1 of FYVE, RhoGEF and PH domain-containing protein 6 OS=Gallus gallus OX=9031 GN=FGD6 PE=4 SV=1 CANONICAL=A0A8V0YCC0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0/entry#A0A8V0YCC0-1", "sequence": { "sequence": "MRSAGGQEGEEIKKPPVAPKPKFVVGHKATPPPVAPKPDVVLSGVLQAARKTKPAIAPKPKVLKSSSIPEVKPPSCARKGTKSFEEHRGDSSQTLDHLNYKNEVSEGSTDNTAYILPMSSCKFECLHKLGNGENTCKTQIILEHFENLENIKVDEKTALSLGSSPSEKMANRNQVVVKASILEEKLKDVLTHGVFPNRSPVRHRYADRLYKGDGNSSTNDVKIEFMELVQSSSSEVANGRQQNTGSKLTEDEFQTSETCPSLNENHSSFSCLLNQEILENENVNSSSSFSGEMGMKIDTGKTSSETCSALSSKMLPIPKPRKPRAACLVRQDGIDSVGEGTKEPSSSENDSFGPAEHSFKKPAKINVLGQSVCYNNHTEALNPEKSEITQSIADRMHLRKEPADTEESTLQNLLPQLSHKTSDLVENVECPLDTDHNLSSSVDRMTDDASMPDTVDKRTSFIRCDALSMSLPKQIKLPVSQHLPAANSLHVSLQKVEDREAKIKDESSPKIVPKKPQRHSLPAAGVLKKAASAELVEKSSYTSSEDKSNSVLEGSHFSHSPAREQGALSSSDIPRRSSEKPVWKLPHPILPFSGNSESLKTASIAPSFSHVSAVTKPRAKSLSSVDMERTDKPCKDTQKKNSLKKFLNVKLSVCLMKSDFQKLLSKGSQSMDSSTANLSTGEGYGNGNSRHVASVGSERKAKSAKARSVEISSPALQKKRQRNRSQPEMRSNQRLESLDGHSLPGENLSQMHLNSVTSNCAPEYENLRHYEEIPEYENLPFAMGAGKNLCLEWQNSSRVEDPSSSLYEVEEPFQAASRRVRHGRSLEEHHDHPGMVIGDLQSDDEDIVNSSDEDDDTNSDSSKGEPDSQDQSKAAGKKTKVYHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLRELEERLSHWLEHQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNAGFASVVKDFEMSPRCASLALKHYLLKPVQRIPQYRLLLTDYLKNLLEESADYRDTQDALAVVIEVANHANDIMKQGDNFQKLMQIQYSLNGHHEIVQPGRIFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVKKPSQEAYQNELNIESVERSFILSASSATERDEWLEAISRSIEDYAKKRITFNPSKSLEEADTEKQEEASPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKHGLDYMKNQPARVCDHCFRELQKQDNQCSPKTGSPVNHKSPSSALSTVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLHRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVSEVRDENSESRVFHLLHKNTLFYIFKADDPHSAQKWIEAFQEGTVL", "length": 1439, "header": "tr|A0A8V0YCC0-1|A0A8V0YCC0_CHICK Isoform 1 of FYVE, RhoGEF and PH domain-containing protein 6 OS=Gallus gallus OX=9031 GN=FGD6 PE=4 SV=1 CANONICAL=A0A8V0YCC0-1" }, "locus": { "chromosome": "1", "start_pos": 45488868, "end_pos": 45425920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028084.1", "url": "https://www.ensembl.org/id/ENSGALT00010028084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016112.1", "url": "https://www.ensembl.org/id/ENSGALP00010016112.1" } ] } }, { "isoform_ac": "A0A8V0YEJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0/entry#A0A8V0YEJ5-1", "sequence": { "sequence": "MSSAEIKKPPVAPKPKFVVGHKATPPPVAPKPDVVLSGVLQAARKTKPAIAPKPKVLKSSSIPEVKPPSCARKGTKSFEEHRGDSSQTLDHLNYKNEVSEGSTDNTAYILPMSSCKFECLHKLGNGENTCKTQIILEHFENLENIKVDEKTALSLGSSPSEKMANRNQVVVKASILEEKLKDVLTHGVFPNRSPVRHRYADRLYKGDGNSSTNDVKIEFMELVQSSSSEVANGRQQNTGSKLTEDEFQTSETCPSLNENHSSFSCLLNQEILENENVNSSSSFSGEMGMKIDTGKTSSETCSALSSKMLPIPKPRKPRAACLVRQDGIDSVGEGTKEPSSSENDSFGPAEHSFKKPAKINVLGQSVCYNNHTEALNPEKSEITQSIADRMHLRKEPADTEESTLQNLLPQLSHKTSDLVENVECPLDTDHNLSSSVDRMTDDASMPDTVDKRTSFIRCDALSMSLPKQIKLPVSQHLPAANSLHVSLQKVEDREAKIKDESSPKIVPKKPQRHSLPAAGVLKKAASAELVEKSSYTSSEDKSNSVLEGSHFSHSPAREQGALSSSDIPRRSSEKPVWKLPHPILPFSGNSESLKTASIAPSFSHVSAVTKPRAKSLSSVDMERTDKPCKDTQKKNSLKKFLNVKLSVCLMKSDFQKLLSKGSQSMDSSTANLSTGEGYGNGNSRHVASVGSERKAKSAKARSVEISSPALQKKRQRNRSQPEMRSNQRLESLDGHSLPGENLSQMHLNSVTSNCAPEYENLRHYEEIPEYENLPFAMGAGKNLCLEWQNSSRVEDPSSSLYEVEEPFQAASRRVRHGRSLEEHHDHPGMVIGDLQSDDEDIVNSSDEDDDTNSDSSKGEPDSQDQSKAAGKKTKVYHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLRELEERLSHWLEHQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNAGFASVVKDFEMSPRCASLALKHYLLKPVQRIPQYRLLLTDYLKNLLEESADYRDTQDALAVVIEVANHANDIMKQGDNFQKLMQIQYSLNGHHEIVQPGRIFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVKKPSQEAYQNELNIESVERSFILSASSATERDEWLEAISRSIEDYAKKRITFNPSKSLEEADTEKQEEASPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKHGLDYMKNQPARVCDHCFRELQKQDNQCSPKTGSPVNHKSPSSALSTVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLHRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVSEVRDENSESRVFHLLHKNTLFYIFKADDPHSAQKWIEAFQEGTVL", "length": 1433, "header": "tr|A0A8V0YEJ5-1|A0A8V0YCC0_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain-containing protein 6 OS=Gallus gallus OX=9031 GN=FGD6 PE=4 SV=1 CANONICAL=A0A8V0YCC0-1" }, "locus": { "chromosome": "1", "start_pos": 45490475, "end_pos": 45425920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028087.1", "url": "https://www.ensembl.org/id/ENSGALT00010028087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016113.1", "url": "https://www.ensembl.org/id/ENSGALP00010016113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7L6-1", "protein_name": "FYVE, RhoGEF and PH domain containing 6", "gene_name": "Fgd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "FFPLELKKPPLAPKPKLVGTNNKSPPPPIAPKPDIGNASVPRLTKTKPAIAPKPKVLTNSDVQDVKDQPSKKLTLNLEEREPELPESTGKFNCKDVGDAHGDYIFPTCSCSSGCTHEPRTRENLCAEQLVLEPLGMKEHLENGKNGESSKRGSRWNSSREKCRSQSGVVLKASIFEEKLKEVLTQPRSRSPSSSPRKHRCPNKPEMNGDHSCARQVRIEFADTSSSQSSFGKAPHSCHTQPPRDKSQNLQTCQDGSAESLGPFHSCELEGKRGCSGGTSQKSEVQGLGPVEIHLLPYTSKFPTPKPRRTHAARLRRQKHVDTPSESTEEPESSNNGSSCLHEDSLKNNKVSVLHQNALSNQGPVDEVRPGNKKALTRESNSDRQDSVSSQKAVQHETSSFEKVAPSLDTDSSLTSDSTVEDGSDVLPAVDRETAFIQCSPQPLSLPKQVKLACAEQQPTTCNREVSVPQIQKESSSRIVPKKPQRHSLPAAGVLKKAASEELVEKNSSSKETNSEKGLQRNHLQHLGPSNHGMSPSSFDMPNPTSEKPVWKLPHPILPFPGSPEALKRVTLSLNNEPSISLTKPRAKSLSAVDMDRCSKPCKEPPKKTTFKKLINVKLSIGFIKSDFHKFKSKNCQHGDVSTGHSLGREPKGLENNWQGLATGEEKKSKPIKAYSEENCSLESQKVKSWSQSSATNGQRAESLDDQMLSRHASCQASSTSDCGPEYENVRHYEEIPEYENLPFVMARGNPPELGWQNSSSVEDTDVSLYEVEEPYDAPDGQLQLDPRHQPCSSGRCQDRQDELHLDLPSDEEVINSSDEDDVSSESSKGEPDPLEDKQDEDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLSWAEQQRIADIFVKKGPYLKMYSMYIKEFDKNIALLDEQCKKNSGFATVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGILMKLSRKVMQPRMIFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSASERDDWLEAISRAIEEYAKKRITFCPSRSLDEDSERKEEVSPLGAKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKCGLDYLKGQPARVCELCFQELQKLDHQLSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVAQVKDEHSDPRVFQLLHKGLLFYVFKADDAHSTQSTLPLSFQKGLVLFSQLWS", "length": 1412 }, "evidence": [ { "id": "A0A8V0YCC0", "url": "https://omabrowser.org/oma/group/A0A8V0YCC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2MUN7-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "Fgd6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTSAAELKKPPLAPKPKLMGTNNKPQPPPIAPKPDIMNASVPRLTQKTKPTIAPKPKALTNSVVQDIKQSPSKKIPLNLGEREPELPESTDKFNCKDVRDPHSDYILPTCSCSSGCIQEPGSRESLCAKQLVLEPLGMKDNLGNNKNGESSLTAKRGTKWDSSGEKGQSQSGVILKASILEEKLKEVLTRQQSPCSSPRKHRSPYNTEMNGDYSCSRQIRIEFADLSPSLSSFEKVPAHHSCQLQLPRDESQNLETCHTGNSKSNSHFHSCELNDRKMSSDGTSKKTEVTDLGPLEIHLLPYTSKFPTPKPRRTHTARLLRQKYVDTPSESTEEPENSNNGSSCLLENSLKNNQVSVLHQVLYNQGQVDKVKPANKRAVTSDSKSDRQDSVNSQKAVRHETSSSEKVAPVLDADSILGPDSTAEDVSGMLPAVDKEISFIQCNTQSESLPKQVKLSCTEHPPTTCNVELSVPQIQKEPSSKIVPKKPQRHSLPTAGVLKKAASEELVEKNSYSSRKATNSEKGLERNHFQHLGPSSRGISSSSFDTPNSTSEKPVWKLPHPILPFSGSPESLKRVTLSLNNEPSISLTKPRAKSLSAVDMDRCNKPCKELPKKTSFKKLINVKLSIGFIKSDFQKFRSKSYQQADVTTGHLLSREPKKLESDWQGLVTGEEKRSKPIKAYSAENCSLESQKVKSWGQTSAANGQRAESLDDQLLSRDSSCQVSYKSSTSGCVPEYENVCHYEEIPEYENLPFVTAGGKTPELGWQNSSSAEDTDANLYEVEEPYDAPDGQLQLDPRHQPSSSGTPKEGQDDLNLGLGDLPSDEEVINSSDEDDVSSESSKGEPDPMEDKQGEDTGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLSWNEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDDWLEAISRSIEEYAKKKITFCPSRSLDEDSEKKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKRQLARVCEHCFQELQKLDHQLPPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTQVKDENSESKVFQLLHKGMVFYVFKADDAHSTQKWIEAFQEGTIL", "length": 1417 }, "evidence": [ { "id": "A0A8V0YCC0", "url": "https://omabrowser.org/oma/group/A0A8V0YCC0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MQ30-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "FGD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSAAEIKKPPVAPKPKFVLAANKPAPPPVAPKPEILVSSVPQSTKKTKPSIAPKPKVLKASPVQDITQSPSRKIVVNLEEHTQEFPESIDNSNCRNRGHPSSDYILPVCSCHPGCNHKLESRKNLYVKQLVLGPLEMHENLENNKIGESPSAVKNQHKCDSVGERVKSQSKVVLKASILEEKLKDVLTQPMSPFLFPQKHRSTDSPEMSDGCNSHRQFSIEFADLSPSLSSFENVSNHHPCHLQLPSTEFQNFETNQNDSEKSNTCYHSSEQEALENGKRSPFLSSDGDSKKSEARDLGPLEIHLVPCTPKFPTPKPRKTHVARLLRQRHIDTSSESTEEPEDVDSLPHVFEDSLKNNKISVFHQTALCNQEQVDKVKPENKGELNVDLTGDRQNSVYSQKALRPETFSSEKTAPPLETDSNLSSDDKSGDSSGMSLAEDKGISFIRCSTLSMSLPKQLKLTCSEHLPTASNPGVSAPQMQKESMIKGESSSKVVPKKPQRHSLPAAGVLKKAASEELLEKSSYPSNEEKDAEKGLERDHVQHLCAPNNGMSSSFDMPKRASEKPVWKLPHPIIPFSGNPESLKSVTISSNSETPTPLTKPRAKSLSAMDVERCTKPCKDSHKKNSLKKLLNMKLSICFMKSDFQKFWSKHSHLGDTTSGSLAGGEQRGSESDWHGLLVGEEKRSKPIKAYSADNYSLESHKKRKKLRGHTNAANGPRAESLDDQMLSRESSLQAPCKSVTSDCVPEYENIRHYEEIPEYENLPFVMAMGKTPELERRNSSSVEDTDANVYEVQEPYEAPDGQLQLGPRHQHSSSSGASQEGQSDLDLGLGDLPSDEEEVINSSDEDDVSSASSKGEPDLLDDKQGEDTGMKCKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMSNWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSAPERDEWLEAISRSIEEYAKKRITFCPSRSLDEADSEDKDEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPKFGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTQVKDENSESRVFQLLHKNMLFYVFKADDAHSAQKWIEAFQEGTIL", "length": 1434 }, "evidence": [ { "id": "A0A8V0YCC0", "url": "https://omabrowser.org/oma/group/A0A8V0YCC0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q69ZL1-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "Fgd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSAAELKKPPLAPKPKLVGTNNKPPPPPIAPKPDIGSASVPRLTKKTKPAIAPKPKVPTNSVVQDIKHPPSKKPTLNLEEREPELPESTGKSNCKDVRDPHSDYILPTCSCSSGCIHEPRTRETQCVEQLVLEPLGMKENLENSKNGESSKRGSSWDSSSEKCRGQSGVVLKASILEEKLKEVLTQQRSPCGSPGRHRAPKKPEMNGDHSCTRQIRIEFADVSSSLTGFEKVPAHHNCHPQLPRDESQTLKTCQDGSAESRGHTDSCEPENKRVASDGISQKTEVKGLGPLEIHLLPYTSKFPTPKPRKTHAAARLRRQKHVDTPGESTEEPGNSNNGSSCLLEDYCLKNNKVSVLRQNALYNQGPVDEVRPANQRALTGDSNSGGQDSVGSQKAVQQQTPSLDTDSSLTSDSSGSGVSPAVDKETTYTQCSTQPLSLPKQVTSACTDQPPATCNPEVSAPPIQKESSSSRIIPKKPQRHSLPAAGVLKKAASEELVEKSSSGKETNVEKGLHRNYLHHPGPPNHGASASPFDMPNPTSEKPVWKLPHPILPFSGSPEALKRVTLSLNNEPSVSLTKPRAKSLSAVDADRCNKPCKDPPKKTSFKKLINVKLSIGFIKSDFQKIRSKSCQHGDVSAGHPLAREPKGLESDWQGLATGEEKRSKPTKAHSAENCSLESQKVKSWGQSSAVNGQRAESLDDRILSRHTSCTGDFGPEYENVRHYEEIPEYENLPFVMAGRNTPDLGWQNSSSVEDTDASLYEVEEPYNAPDGQLQLDPRHQPCSSGTSQEGKDALHLGLSDLPSDEEVINSSDEDDVSSESSKGEPDPLEDKQDEDAGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRGAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLTWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNVALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLLEDSVDHRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLSGHHEIVQPGRVFLKEGTLMKLSRKVMQPRMFFLFNDALLYTTPMQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSAAERDDWLEAISSSIEEYAKKRITFCPSRSLDEDSERKEEVSPLGAKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKGQLARVCEHCFQELQKLDHQLSPRVGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKVLYTYAASEDVAALESQPLLGFTVTLVKDENSESKVFQLLHKGMVFYVFKADDAHSTQRWIDAFQEGTVL", "length": 1399 }, "evidence": [ { "id": "A0A8V0YCC0", "url": "https://omabrowser.org/oma/group/A0A8V0YCC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZV73-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 6", "gene_name": "FGD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAAEIKKPPVAPKPKFVVANNKPAPPPIAPKPDIVISSVPQSTKKMKPAIAPKPKVLKTSPVREIGQSPSRKIMLNLEGHKQELAESTDNFNCKYEGNQSNDYISPMCSCSSECIHKLGHRENLCVKQLVLEPLEMNENLENSKIDETLTIKTRSKCDLYGEKAKNQGGVVLKASVLEEELKDALIHQMPPFISAQKHRPTDSPEMNGGCNSNGQFRIEFADLSPSPSSFEKVPDHHSCHLQLPSDECEHFETCQDDSEKSNNCFQSSELEALENGKRSTLISSDGVSKKSEVKDLGPLEIHLVPYTPKFPTPKPRKTRTARLLRQKCVDTPSESTEEPGNSDSSSSCLTENSLKINKISVLHQNVLCKQEQVDKMKLGNKSELNMESNSDAQDLVNSQKAMCNETTSFEKMAPSFDKDSNLSSDSTTVDGSSMSLAVDEGTGFIRCTVSMSLPKQLKLTCNEHLQSGRNLGVSAPQMQKESVIKEENSLRIVPKKPQRHSLPATGVLKKAASEELLEKSSYPSSEEKSSEKSLERNHLQHLCAQNRGVSSSFDMPKRASEKPVWKLPHPILPFSGNPEFLKSVTVSSNSEPSTALTKPRAKSLSAMDVEKCTKPCKDSTKKNSFKKLLSMKLSICFMKSDFQKFWSKSSQLGDTTTGHLSSGEQKGIESDWQGLLVGEEKRSKPIKAYSTENYSLESQKKRKKSRGQTSAANGLRAESLDDQMLSRESSSQAPYKSVTSLCAPEYENIRHYEEIPEYENLPFIMAIRKTQELEWQNSSSMEDADANVYEVEEPYEAPDGQLQLGPRHQHSSSGASQEEQNDLGLGDLPSDEEEIINSSDEDDVSSESSKGEPDPLEDKQDEDNGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLHWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPWKHFWFVIKNKVLYTYAASEDVAALESQPLLGFTVIQVKDENSESKVFQLLHKNMLFYVFKAEDAHSAQKWIEAFQEGTIL", "length": 1430 }, "evidence": [ { "id": "A0A8V0YCC0", "url": "https://omabrowser.org/oma/group/A0A8V0YCC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 880, "end_pos": 1069, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YCC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 1231, "end_pos": 1290, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0YCC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1098, "end_pos": 1192, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 677, "end_pos": 679 }, { "start_pos": 723, "end_pos": 725 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 795, "end_pos": 797 }, { "start_pos": 849, "end_pos": 851 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCC1-1", "uniprot_ac": "A0A8V0YCC1", "uniprot_id": "A0A8V0YCC1_CHICK", "mass": { "chemical_mass": 61096.0, "monoisotopic_mass": 61096.0 }, "refseq": { "ac": "XP_040520921", "name": "chromodomain Y-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520921" }, "gene_names": [ { "name": "CDYL", "type": "recommended", "evidence": [ { "id": "A0A8V0YCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ] }, { "name": "CDYL", "type": "synonym", "evidence": [ { "id": "XP_040520921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520921" } ] } ], "protein_names": [ { "name": "Chromodomain Y like", "type": "synonym", "evidence": [ { "id": "A0A8V0YCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1/entry#names_and_taxonomy" } ] }, { "name": "chromodomain Y-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040520921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520921" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040520921.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040520921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520921" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDYL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18634", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18634", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420877", "url": "https://www.ncbi.nlm.nih.gov/gene/420877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VPRSPMN", "url": "https://omabrowser.org/oma/group/VPRSPMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCC1", "url": "https://www.orthodb.org/?gene=A0A8V0YCC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00378", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00378", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040520921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040520921", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHEFNRRHNEKQKESTLTRTNRTSPNNARKQISRSTNSSFSKTSTKSLVMSKDHESKNNQLFTATQKFRKNNSPSLSGRKNMDLAKSGIKILVPKSPIKSRTAVDGFQNESPDKMDHTEQDQEDSVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQLPVPVTATIASALTINGKGTSTFMEALAANGTTNIQTSVTGVTASKRRFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALNTAAADDSKLVLFSAVGSIFCCGLDFIYFIRRLTDDRKKESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSSLTFPRIMGLASANEMLFSGRKLTAQEACAKGLVSQVFWPGTFTQEVMVRIKELVTCNSVVLEESKALVRNIMKVDLEQANEKECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 544, "header": "tr|A0A8V0YCC1-1|A0A8V0YCC1_CHICK Isoform 1 of Chromodomain Y like OS=Gallus gallus OX=9031 GN=CDYL PE=4 SV=1 CANONICAL=A0A8V0YCC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1/entry#A0A8V0YCC1-1", "sequence": { "sequence": "MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHEFNRRHNEKQKESTLTRTNRTSPNNARKQISRSTNSSFSKTSTKSLVMSKDHESKNNQLFTATQKFRKNNSPSLSGRKNMDLAKSGIKILVPKSPIKSRTAVDGFQNESPDKMDHTEQDQEDSVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQLPVPVTATIASALTINGKGTSTFMEALAANGTTNIQTSVTGVTASKRRFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALNTAAADDSKLVLFSAVGSIFCCGLDFIYFIRRLTDDRKKESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSSLTFPRIMGLASANEMLFSGRKLTAQEACAKGLVSQVFWPGTFTQEVMVRIKELVTCNSVVLEESKALVRNIMKVDLEQANEKECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 544, "header": "tr|A0A8V0YCC1-1|A0A8V0YCC1_CHICK Isoform 1 of Chromodomain Y like OS=Gallus gallus OX=9031 GN=CDYL PE=4 SV=1 CANONICAL=A0A8V0YCC1-1" }, "locus": { "chromosome": "2", "start_pos": 65424646, "end_pos": 65322067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026852.1", "url": "https://www.ensembl.org/id/ENSGALT00010026852.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015303.1", "url": "https://www.ensembl.org/id/ENSGALP00010015303.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E7F6P0-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "cdyl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMATEELYEVERIIGKRKNKKGKTEYLVRWRGYSFEGDTWEPEGHLSSCIEFIHEFNRQHSEKQKDGTLLRSTRSSPSTANTSINARKQISRPQHPSANSNTAKTSTPTPNTHPTKRPQPAQNSSNDSDSPQQKRGRSAGTSSIMGTVTETAPTAAPAAAPTVSALRRSMDLSKSGIKILVPKSPMNSRADTEESPSEAAHSLEQGSQEPDAVPPEVALLEKPAGAMRVPGEERARMGTRPRTQTALPPPQIPITPAAVRTLNGKGVTTLMEASSANGTAITQSAAAGVMSSSGLTGKRRFEERANFDKRLRFSVRQTESAYRYRDIVVKKQDGFTHILFSTKTSENNSLNPDVMKEVQSAMATAAADDSKLVLLSGVGSVFCFGLDFIYFIRRLTDDRKKESIKMAETIRTFVNTFIQFKKPIIAAVNGPAIGLGASILPLCDVIWANEKAWFQTPYTTFGQTPDACSSVTFPLIMGVASANEMLLSGRKLTAQEACAKGLVSQVLWPGTFTQEVMVRIKELVSCNSVVLRESKALVRNINRAALEQANERECEALKRVWGSSQGMDSILKYLQKKIDEF", "length": 581 }, "evidence": [ { "id": "A0A8V0YCC1", "url": "https://omabrowser.org/oma/group/A0A8V0YCC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RX06-1", "protein_name": "Chromodomain Y like", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASEELYEVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHPEKQKEGALARPSRGSPNNARKQISRSTHSSFAKASPKSLVIGKDPEAKASSLFTASQKFRKNPAPSLSQRKNMDLAKSGIKILVPKSPIRSRTAVDGFPSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPPAAGPVTAAMATGLAVNGKGTSPFMDVLTANGPTSLQPSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCSMKPELEQANERECEVLRKIWGSAQGMDSMLKYLQRKIDEF", "length": 544 }, "evidence": [ { "id": "A0A8V0YCC1", "url": "https://omabrowser.org/oma/group/A0A8V0YCC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6AYK9-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "Cdyl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLGSSQPSTKEAEPCTLQEKEEHPVDDTRQQNNAVPATVSDPDQVSPAVQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGTLARANRASPSNARKQISRSTHSALSKTNPKALVVGKDHESKTNQLLATSQKFRKNTAPSLANRKNMDLAKSGIKILVPKSPIKGRTSIDGFHGESPEKLDQGAEDTVTPEVTAEKPTGALLGPGAERARMGSRPRIHSLVPQVSGPVTAAMATTLAVNGKGTSPFMDALTANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPIVLEESKALVRCNMKMELEQANERECDALKKIWGSAQGMDSMLKYLQRKIDEF", "length": 589 }, "evidence": [ { "id": "A0A8V0YCC1", "url": "https://omabrowser.org/oma/group/A0A8V0YCC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTK2-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "Cdyl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIGNSQPNSQEAQLCTLPEKAEQPTDDNTCQQNNVVPATVSEPDQASPAIQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGSLARASRASPSNARKQISRSTHSTLSKTNSKALVVGKDHESKSSQLLAASQKFRKNPAPSLANRKNMDLAKSGIKILVPKSPVKGRTSVDGFQGESPEKLDPVDQGAEDTVAPEVTAEKPTGALLGPGAERARMGSRPRIHPLVPQVSGPVTAAMATGLAVNGKGTSPFMDALAANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 593 }, "evidence": [ { "id": "A0A8V0YCC1", "url": "https://omabrowser.org/oma/group/A0A8V0YCC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y232-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "CDYL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTFQASHRSAWGKSRKKNWQYEGPTQKLFLKRNNVSAPDGPSDPSISVSSEQSGAQQPPALQVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQVPGPVTAAMATGLAVNGKGTSPFMDALTANGTTNIQTSVTGVTASKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 598 }, "evidence": [ { "id": "A0A8V0YCC1", "url": "https://omabrowser.org/oma/group/A0A8V0YCC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" }, { "name": "histone H3K27me3 reader activity", "id": "GO:0061628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" }, { "name": "negative regulation of peptidyl-lysine crotonylation", "id": "GO:0120094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC1" }, { "id": "PS50013", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 67, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCC8-1", "uniprot_ac": "A0A8V0YCC8", "uniprot_id": "A0A8V0YCC8_CHICK", "mass": { "chemical_mass": 24199.0, "monoisotopic_mass": 24199.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Interleukin 17B", "type": "synonym", "evidence": [ { "id": "A0A8V0YCC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF06083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWVPLHCSAPWGQLCIALCLSLPCAGLQVCVLLTPGLLLCIFTFAMVLVPEAKDESRAAKGRRRGPSRLPTAASALAWAPDDPYTPMEDYERSIQDMVHQLRNGSEPGDTKCQVNLRLWRSNRRSLSPWAYSINHDATRIPADIPEARCLCTGCINPFTMQEDRTMASIPIYSRLPVRRLLCQAPGKVGHKASGRKKCHKKYQTVMETIAVGCTCIF", "length": 218, "header": "tr|A0A8V0YCC8-1|A0A8V0YCC8_CHICK Isoform 1 of Interleukin 17B OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8/entry#A0A8V0YCC8-1", "sequence": { "sequence": "MGWVPLHCSAPWGQLCIALCLSLPCAGLQVCVLLTPGLLLCIFTFAMVLVPEAKDESRAAKGRRRGPSRLPTAASALAWAPDDPYTPMEDYERSIQDMVHQLRNGSEPGDTKCQVNLRLWRSNRRSLSPWAYSINHDATRIPADIPEARCLCTGCINPFTMQEDRTMASIPIYSRLPVRRLLCQAPGKVGHKASGRKKCHKKYQTVMETIAVGCTCIF", "length": 218, "header": "tr|A0A8V0YCC8-1|A0A8V0YCC8_CHICK Isoform 1 of Interleukin 17B OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCC8-1" }, "locus": { "chromosome": "13", "start_pos": 8128567, "end_pos": 8119191, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028109.1", "url": "https://www.ensembl.org/id/ENSGALT00010028109.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016123.1", "url": "https://www.ensembl.org/id/ENSGALP00010016123.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCD7-1", "uniprot_ac": "A0A8V0YCD7", "uniprot_id": "A0A8V0YCD7_CHICK", "mass": { "chemical_mass": 68298.0, "monoisotopic_mass": 68298.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YCD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWGGVGKVLEGQRGVGKVLEGQRGVGKVLEDQSWVGKVLEGQRGVKKVLEGQSWVGKVLEDQRCVGKVLEDQSCVGKVLEGQRWIEKVLEGQRWVGKVLEGQKGGMVGLERSWKAKGVLERSWKIKGGLKRSWKVKGGLKKSWKVKGGLERSWKVKGGLERSWKIKVGLERSWKAEVGLERSWKVKGGLERSWKVKGGLKRSWKVKGGLERSWKTKVGLKRSWKTIGRLKWSWKIKGGLKRSWKVKGGLKRSWKAKGGLERSWKVKGGLERSWKTIGGLERSWKVKRGGMGGLERSWKAKVGLKRSWKIKGGLERSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKVKGRRNGGVGKVLEGRRWVGPNAAPIWGRRAHLWGNAAPFVGSKGPYGVEGCPYLGSTVHMGNIYGAALPPCGVEGSIWGRRVHMGSEGPYGVHLWGNTAPLWGQRVFLGSEGPFGVHLWGNAAPLWGRRVLMVFICGAMLPPGGQSPLLLWGRRLPLFGVGGPIYGATLPPCGVERPIWGPYGVHLWCNAAPWWPKSVTALGSEAAPIWGRRSIWGRRLPLFGV", "length": 614, "header": "tr|A0A8V0YCD7-1|A0A8V0YCD7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCD7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7/entry#A0A8V0YCD2-1", "sequence": { "sequence": "MRRVAVTFQDLKGPHRREWDSCCDLPGPKGFPIGSWLGKVLEGQRRMEWGGVGKVLEGQRGVGKVLEGQRGVGKVLEDQSWVGKVLEGQRGVKKVLEGQSWVGKVLEDQRCVGKVLEDQSCVGKVLEGQRWIEKVLEGQRWVGKVLEGQKGGMVGLERSWKAKGVLERSWKIKGGLKRSWKVKGGLKKSWKVKGGLERSWKVKGGLERSWKTKVGLKRSWKTIGRLKWSWKIKGGLKRSWKVKGGLKRSWKAKGGLERSWKVKGGLERSWKAKVGLKRSWKIKGGLERSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKVKGRRNGGVGKVLEGRRWVGPNAAPIWGRRAHLWGNAAPFVGSKGPYGVEGCPYLGSTVHMGNIYGAALPPCGVEGSIWGRRVHMGSEGPYGVHLWGNTAPLWGQRVFLGSEGPFGVHLWGNAAPLWGRRVLMVFICGAMLPPGGQSPLLLWGRRLPLFGVGGPIYGATLPPCGVERPIWGPYGVHLWCNAAPWWPKSVTALGSEAAPIWGRRSIWGRRLPLFGV", "length": 566, "header": "tr|A0A8V0YCD2-1|A0A8V0YCD7_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCD7-1" }, "locus": { "chromosome": "W", "start_pos": 130283, "end_pos": 128101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028845.1", "url": "https://www.ensembl.org/id/ENSGALT00010028845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016604.1", "url": "https://www.ensembl.org/id/ENSGALP00010016604.1" } ] } }, { "isoform_ac": "A0A8V0YCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7/entry#A0A8V0YCD7-1", "sequence": { "sequence": "MEWGGVGKVLEGQRGVGKVLEGQRGVGKVLEDQSWVGKVLEGQRGVKKVLEGQSWVGKVLEDQRCVGKVLEDQSCVGKVLEGQRWIEKVLEGQRWVGKVLEGQKGGMVGLERSWKAKGVLERSWKIKGGLKRSWKVKGGLKKSWKVKGGLERSWKVKGGLERSWKIKVGLERSWKAEVGLERSWKVKGGLERSWKVKGGLKRSWKVKGGLERSWKTKVGLKRSWKTIGRLKWSWKIKGGLKRSWKVKGGLKRSWKAKGGLERSWKVKGGLERSWKTIGGLERSWKVKRGGMGGLERSWKAKVGLKRSWKIKGGLERSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKVKGRRNGGVGKVLEGRRWVGPNAAPIWGRRAHLWGNAAPFVGSKGPYGVEGCPYLGSTVHMGNIYGAALPPCGVEGSIWGRRVHMGSEGPYGVHLWGNTAPLWGQRVFLGSEGPFGVHLWGNAAPLWGRRVLMVFICGAMLPPGGQSPLLLWGRRLPLFGVGGPIYGATLPPCGVERPIWGPYGVHLWCNAAPWWPKSVTALGSEAAPIWGRRSIWGRRLPLFGV", "length": 614, "header": "tr|A0A8V0YCD7-1|A0A8V0YCD7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCD7-1" }, "locus": { "chromosome": "W", "start_pos": 130145, "end_pos": 128101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028850.1", "url": "https://www.ensembl.org/id/ENSGALT00010028850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016609.1", "url": "https://www.ensembl.org/id/ENSGALP00010016609.1" } ] } }, { "isoform_ac": "A0A8V0YDN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7/entry#A0A8V0YDN9-1", "sequence": { "sequence": "MRRVAVTFQDLKGPHRREWDSCCDLPGPKGFPIGSWLGKVLEGQRRMEWGGVGKVLEGQRGVGKVLEGQRGVGKVLEDQSWVGKVLEGQRGVKKVLEGQSWVGKVLEDQRCVGKVLEDQSCVGKVLEGQRWIEKVLEGQRWVGKVLEGQKGGMVGLERSWKAKVGLERSWKVKGGLERSWKVKGGLKRSWKVKGGLERSWKTKVGLKRSWKTIGRLKWSWKIKGGLKRSWKVKGGLKRSWKAKGGLERSWKVKGGLERSWKIKGGLERSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKVKGRRNGGVGKVLEGRRWVGPNAAPIWGRRAHLWGNAAPFVGSKGPYGVEGCPYLGSTVHMGNIYGAALPPCGVEGSIWGRRVHMGSEGPYGVHLWGNTAPLWGQRVFLGSEGPFGVHLWGNAAPLWGRRVLMVFICGAMLPPGGQSPLLLWGRRLPLFGVGGPIYGATLPPCGVERPIWGPYGVHLWCNAAPWWPKSVTALGSEAAPIWGRRSIWGRRLPLFGV", "length": 546, "header": "tr|A0A8V0YDN9-1|A0A8V0YCD7_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCD7-1" }, "locus": { "chromosome": "W", "start_pos": 130283, "end_pos": 128101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028853.1", "url": "https://www.ensembl.org/id/ENSGALT00010028853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016612.1", "url": "https://www.ensembl.org/id/ENSGALP00010016612.1" } ] } }, { "isoform_ac": "A0A8V0YFV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7/entry#A0A8V0YFV3-1", "sequence": { "sequence": "MEWGGVGKVLEGQRGVGKVLEGQRGVGKVLEGQRWIEKVLEGQRWVGKVLEGQKGGMVGLERSWKAKGVLERSWKIKGGLKRSWKVKGGLERSWKIKVGLERSWKAEVGLERSWKVKGGLERSWKVKGGLKRSWKVKGGLERSWKTKVGLKRSWKTIGRLKWSWKIKGGLKRSWKVKGGLKRSWKAKGGLERSWKVKGGLERSWKTIGGLERSWKVKRGGMGGLERSWKAKVGLKRSWKIKGGLERSWKVKGGLERSWKIKGGLKRSWKVKGGLERSWKVKRGEWWGWKGPGRPKLGWKGPGRSKGGWKGPGRSKVD", "length": 317, "header": "tr|A0A8V0YFV3-1|A0A8V0YCD7_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCD7-1" }, "locus": { "chromosome": "W", "start_pos": 130145, "end_pos": 128883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028854.1", "url": "https://www.ensembl.org/id/ENSGALT00010028854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016613.1", "url": "https://www.ensembl.org/id/ENSGALP00010016613.1" } ] } }, { "isoform_ac": "A0A8V0YKL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD7/entry#A0A8V0YKL8-1", "sequence": { "sequence": "MRRVAVTFQDLKGPHRREWDSCCDLPGPKGFPIGSWLGKVLEGQRRMEWGGVGKVLEGQRGVGKVLEGQRGVGKVLEDQSWVGKVLEGQRGVKKVLEGQSWVGKVLEDQRCVGKVLEDQSCVGKVLEGQRWIEKVLEGQRWVGKVLEGQKGGMVGLERSWKAKGVLERSWKIKGGLKRSWKVKGGLKKSWKVKGGLERSWKAEVGLERSWKVKGGLERSWKVKGGLKRSWKVKGGLERSWKTKVGLKRSWKTIGRLKWSWKIKGGLKRSWKVKGGLKRSWKAKGGLERSWKVKGGLERSWKTIGGLERSWKVKRGGMGGLERSWKAKVGLKRSWKIKGGLERSWKVKGGLERSWKIKGRRNGGVGKVLEGRRWVGPNAAPIWGRRAHLWGNAAPFVGSKGPYGVEGCPYLGSTVHMGNIYGAALPPCGVEGSIWGRRVHMGSEGPYGVHLWGNTAPLWGQRVFLGSEGPFGVHLWGNAAPLWGRRVLMVFICGAMLPPGGQSPLLLWGRRLPLFGVGGPIYGATLPPCGVERPIWGPYGVHLWCNAAPWWPKSVTALGSEAAPIWGRRSIWGRRLPLFGV", "length": 580, "header": "tr|A0A8V0YKL8-1|A0A8V0YCD7_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCD7-1" }, "locus": { "chromosome": "W", "start_pos": 130283, "end_pos": 128101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028842.1", "url": "https://www.ensembl.org/id/ENSGALT00010028842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016601.1", "url": "https://www.ensembl.org/id/ENSGALP00010016601.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCE3-1", "uniprot_ac": "A0A8V0YCE3", "uniprot_id": "A0A8V0YCE3_CHICK", "mass": { "chemical_mass": 70416.0, "monoisotopic_mass": 70416.0 }, "refseq": { "ac": "XP_004940038", "name": "grainyhead-like protein 2 homolog isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940038" }, "gene_names": [ { "name": "GRHL2", "type": "recommended", "evidence": [ { "id": "A0A8V0YCE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ] }, { "name": "GRHL2", "type": "synonym", "evidence": [ { "id": "XP_004940038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940038" } ] } ], "protein_names": [ { "name": "Grainyhead like transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YCE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3/entry#names_and_taxonomy" } ] }, { "name": "grainyhead-like protein 2 homolog isoform X5", "type": "synonym", "evidence": [ { "id": "XP_004940038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940038" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940038" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRHL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3", "locus": { "chromosome": "2", "start_pos": 128455895, "end_pos": 128394459, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011772", "url": "https://www.ensembl.org/id/ENSGALG00010011772" } ] } } ], "crossref": [ { "id": "A0A8V0YCE3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "429506", "url": "https://www.ncbi.nlm.nih.gov/gene/429506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCE3", "url": "https://www.orthodb.org/?gene=A0A8V0YCE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11037:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11037:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940038", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQETDNNKRLVALVPNDTSFNTRRAYTSEDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRDKRLLSVNKVNDNQEDQDKRNCLSSTEAQSNLSGGENRVQVLKTVPVNLSLNQDPLESSKRDYNTNVSGSSTPITGTAVTVIKAEEFTPVFMTPQAHYTRGENEEHRGVIFEPYEVSSIAPHTNYLKDDQRSTPDSTYSDTFKDGGTEKYRSVSVGAEEYIYEQTSTFQYTLEATKSLRQKQGEGPMTYLNKGQFYAITLSETGDNKCFRHPISKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHTAKQRVLDIADYKESFNTIGNIEEIAFNAVSFTWDVNEEAKIFITVNCLSTDFSSQKGVKGLPLMIQIDTYSYNNRSNKPIHRAYCQIKVFCDKGAERKIRDEERKQNRKKGKGQASQASCNNSAEGKLSALPLQKKSDITFFKTMTDLDSQPVLFIPDVHFGNLQRTGQVYYNTDDEREGSSVLVKRMFRPVEEEFGPSPLKQMKEEGLKRVLLYVRKETDEVFDALMLKSPTVKGLMEAISEKYGLPVEKIAKLYKKSKKGILVNMDDNIIEHYSNEDTFILHMESVVEGFKITLTEI", "length": 618, "header": "tr|A0A8V0YCE3-1|A0A8V0YCE3_CHICK Isoform 1 of Grainyhead like transcription factor 2 OS=Gallus gallus OX=9031 GN=GRHL2 PE=1 SV=1 CANONICAL=A0A8V0YCE3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3/entry#A0A8V0YCE3-1", "sequence": { "sequence": "MSQETDNNKRLVALVPNDTSFNTRRAYTSEDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRDKRLLSVNKVNDNQEDQDKRNCLSSTEAQSNLSGGENRVQVLKTVPVNLSLNQDPLESSKRDYNTNVSGSSTPITGTAVTVIKAEEFTPVFMTPQAHYTRGENEEHRGVIFEPYEVSSIAPHTNYLKDDQRSTPDSTYSDTFKDGGTEKYRSVSVGAEEYIYEQTSTFQYTLEATKSLRQKQGEGPMTYLNKGQFYAITLSETGDNKCFRHPISKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHTAKQRVLDIADYKESFNTIGNIEEIAFNAVSFTWDVNEEAKIFITVNCLSTDFSSQKGVKGLPLMIQIDTYSYNNRSNKPIHRAYCQIKVFCDKGAERKIRDEERKQNRKKGKGQASQASCNNSAEGKLSALPLQKKSDITFFKTMTDLDSQPVLFIPDVHFGNLQRTGQVYYNTDDEREGSSVLVKRMFRPVEEEFGPSPLKQMKEEGLKRVLLYVRKETDEVFDALMLKSPTVKGLMEAISEKYGLPVEKIAKLYKKSKKGILVNMDDNIIEHYSNEDTFILHMESVVEGFKITLTEI", "length": 618, "header": "tr|A0A8V0YCE3-1|A0A8V0YCE3_CHICK Isoform 1 of Grainyhead like transcription factor 2 OS=Gallus gallus OX=9031 GN=GRHL2 PE=1 SV=1 CANONICAL=A0A8V0YCE3-1" }, "locus": { "chromosome": "2", "start_pos": 128455148, "end_pos": 128394688, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028148.1", "url": "https://www.ensembl.org/id/ENSGALT00010028148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016140.1", "url": "https://www.ensembl.org/id/ENSGALP00010016140.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "epithelium migration", "id": "GO:0090132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090132", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "keratinocyte differentiation", "id": "GO:0030216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "neural tube development", "id": "GO:0021915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "epithelial cell morphogenesis", "id": "GO:0003382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "lung epithelial cell differentiation", "id": "GO:0060487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCE3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCE3", "url": 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"protein_names": [ { "name": "Chromosome 5 open reading frame 24", "type": "synonym", "evidence": [ { "id": "A0A8V0YCG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8/entry#names_and_taxonomy" } ] }, { "name": "UPF0461 protein C5orf24 homolog isoform X4", "type": "synonym", "evidence": [ { "id": "XP_015149583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149583" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C5orf24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8", "locus": { "chromosome": "13", "start_pos": 15276513, "end_pos": 15291087, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013180", "url": "https://www.ensembl.org/id/ENSGALG00010013180" } ] } } ], "crossref": [ { "id": "416311", "url": "https://www.ncbi.nlm.nih.gov/gene/416311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416311", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416311", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAHFDLC", "url": "https://omabrowser.org/oma/group/TAHFDLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCF8", "url": "https://www.orthodb.org/?gene=A0A8V0YCF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCG8", "url": "https://www.orthodb.org/?gene=A0A8V0YCG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHZ3", "url": "https://www.orthodb.org/?gene=A0A8V0YHZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQM8", "url": "https://www.orthodb.org/?gene=A0A8V0YQM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31894:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31894:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17724", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17724", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMHPVASSNAAFCGTGKSSCLNEDNVRAADQFDLYATQQSKYSHAVSHKPIACQRQDALNESHLQTTSGRNIETKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKAQSRFANLSYTCGSAAFPYPMVHNRGVHAVGETSSKLKQPNE", "length": 188, "header": "tr|A0A8V0YCG8-1|A0A8V0YCG8_CHICK Isoform 1 of Chromosome 5 open reading frame 24 OS=Gallus gallus OX=9031 GN=C5orf24 PE=1 SV=1 CANONICAL=A0A8V0YCG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8/entry#A0A8V0YCF8-1", "sequence": { "sequence": "MKMMHPVASSNAAFCGTGKSSCLNEDNVRAADQFDLYATQQSKYSHAVSHKPIACQRQDALNESHLQTTSGRNIETKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGKKQQAFRCSSDA", "length": 157, "header": "tr|A0A8V0YCF8-1|A0A8V0YCG8_CHICK Computationally mapped isoform of Chromosome 5 open reading frame 24 OS=Gallus gallus OX=9031 GN=C5orf24 PE=1 SV=1 CANONICAL=A0A8V0YCG8-1" }, "locus": { "chromosome": "13", "start_pos": 15287362, "end_pos": 15279705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031619.1", "url": "https://www.ensembl.org/id/ENSGALT00010031619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018485.1", "url": "https://www.ensembl.org/id/ENSGALP00010018485.1" } ] } }, { "isoform_ac": "A0A8V0YCG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8/entry#A0A8V0YCG8-1", "sequence": { "sequence": "MMHPVASSNAAFCGTGKSSCLNEDNVRAADQFDLYATQQSKYSHAVSHKPIACQRQDALNESHLQTTSGRNIETKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKAQSRFANLSYTCGSAAFPYPMVHNRGVHAVGETSSKLKQPNE", "length": 188, "header": "tr|A0A8V0YCG8-1|A0A8V0YCG8_CHICK Isoform 1 of Chromosome 5 open reading frame 24 OS=Gallus gallus OX=9031 GN=C5orf24 PE=1 SV=1 CANONICAL=A0A8V0YCG8-1" }, "locus": { "chromosome": "13", "start_pos": 15282119, "end_pos": 15281556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031638.1", "url": "https://www.ensembl.org/id/ENSGALT00010031638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018503.1", "url": "https://www.ensembl.org/id/ENSGALP00010018503.1" } ] } }, { "isoform_ac": "A0A8V0YHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8/entry#A0A8V0YHZ3-1", "sequence": { "sequence": "MMHPVASSNAAFCGTGKSSCLNEDNVRAADQFDLYATQQSKYSHAVSHKPIACQRQDALNESHLQTTSGRNIETKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPPGSIKAQSRFANLSYTCGSAAFPYPMVHNRGVHAVGETSSKLKQPNE", "length": 172, "header": "tr|A0A8V0YHZ3-1|A0A8V0YCG8_CHICK Computationally mapped isoform of Chromosome 5 open reading frame 24 OS=Gallus gallus OX=9031 GN=C5orf24 PE=1 SV=1 CANONICAL=A0A8V0YCG8-1" }, "locus": { "chromosome": "13", "start_pos": 15282119, "end_pos": 15281556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031612.1", "url": "https://www.ensembl.org/id/ENSGALT00010031612.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018479.1", "url": "https://www.ensembl.org/id/ENSGALP00010018479.1" } ] } }, { "isoform_ac": "A0A8V0YQM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8/entry#A0A8V0YQM8-1", "sequence": { "sequence": "MIPCAALHSHLWHRCLCRKMMHPVASSNAAFCGTGKSSCLNEDNVRAADQFDLYATQQSKYSHAVSHKPIACQRQDALNESHLQTTSGRNIETKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGKKQQAFRCSSDA", "length": 174, "header": "tr|A0A8V0YQM8-1|A0A8V0YCG8_CHICK Computationally mapped isoform of Chromosome 5 open reading frame 24 OS=Gallus gallus OX=9031 GN=C5orf24 PE=1 SV=1 CANONICAL=A0A8V0YCG8-1" }, "locus": { "chromosome": "13", "start_pos": 15282725, "end_pos": 15279705, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031609.1", "url": "https://www.ensembl.org/id/ENSGALT00010031609.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018476.1", "url": "https://www.ensembl.org/id/ENSGALP00010018476.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416311", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416311", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V145-1", "protein_name": "Chromosome 2 C5orf24 homolog", "gene_name": "C5orf24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMHPVASSNPAFCGPGKPSCLNEDAMRAADQFDIYSSQQNKYSHTVSHKPMACQRQDPLNETHLQTTSGRSIEIKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKALSRLADLGYGCGTAAFPYPMMHGRAVHGVEETSSEIKPPNE", "length": 188 }, "evidence": [ { "id": "A0A8V0YCG8", "url": "https://omabrowser.org/oma/group/A0A8V0YCG8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R469-1", "protein_name": "Similar to human chromosome 5 open reading frame 24", "gene_name": "C17h5orf24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMHPVAGGNPAFCGPGKPPCLSDDAAMRAADQFDLYSSQQSKYSHTVSHKPMLCQRQDPLNEAHLQPTSGRNTEIKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKALSRLADLGYGCGTAAFPYPMMHSRVVHGVQETSGEVKPPSE", "length": 189 }, "evidence": [ { "id": "A0A8V0YCG8", "url": "https://omabrowser.org/oma/group/A0A8V0YCG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0II29-1", "protein_name": "UPF0461 protein C5orf24 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMHPVASSNPAFCGPGKPSCLNEDAMRAADQFDIYSSQQNKYSHTVSHKPMVCQRQDPLNETHLQTAGGRSIEIKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKALSRLADLGYGCGTAAFPYPMIHGRAVHGVEETSSEIKPPNE", "length": 188 }, "evidence": [ { "id": "A0A8V0YCG8", "url": "https://omabrowser.org/oma/group/A0A8V0YCG8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z6I8-1", "protein_name": "UPF0461 protein C5orf24", "gene_name": "C5orf24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMHPVASSNPAFCGPGKPSCLNEDAMRAADQFDIYSSQQSKYSHTVNHKPMVCQRQDPLNETHLQTTSGRSIEIKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKALSRLADLGYGCGTAAFPYPMMHGRAVHGVEETSSEVKPPNE", "length": 188 }, "evidence": [ { "id": "A0A8V0YCG8", "url": "https://omabrowser.org/oma/group/A0A8V0YCG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80X32-1", "protein_name": "UPF0461 protein C5orf24 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMHPVAGSNPAFCGPGKPSCLNEDAMRAADQFDLYSSQQNKYSHTVSHKPMVCQRQDPLNETHLQPTSGRNIEIKDELKKKKNLNRSGKRGRPSGTTKSAGYRTSTGRPLGTTKAAGFKTSPGRPLGTTKAAGYKVSPGRPPGSIKALSRLADLGYGCGTAAFPYPMMHSRVVHGLQETSGEVKPPSE", "length": 188 }, "evidence": [ { "id": "A0A8V0YCG8", "url": "https://omabrowser.org/oma/group/A0A8V0YCG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 60, "end_pos": 62 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCI7-1", "uniprot_ac": "A0A8V0YCI7", "uniprot_id": "A0A8V0YCI7_CHICK", "mass": { "chemical_mass": 28647.0, "monoisotopic_mass": 28647.0 }, "refseq": { "ac": "XP_001234192", "name": "regulator of G-protein signaling 7-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234192" }, "gene_names": [ { "name": "RGS7BP", "type": "recommended", "evidence": [ { "id": "A0A8V0YCI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ] }, { "name": "RGS7BP", "type": "synonym", "evidence": [ { "id": "XP_001234192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234192" } ] } ], "protein_names": [ { "name": "Regulator of G protein signaling 7 binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YCI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 7-binding protein", "type": "synonym", "evidence": [ { "id": "XP_001234192", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234192" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001234192.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234192" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGS7BP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7", "locus": { "chromosome": "Z", "start_pos": 20743992, "end_pos": 20706318, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010062", "url": "https://www.ensembl.org/id/ENSGALG00010010062" } ] } } ], "crossref": [ { "id": "A0A8V0YCI7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "770874", "url": "https://www.ncbi.nlm.nih.gov/gene/770874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026512", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026512", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770874", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KDMRDMK", "url": "https://omabrowser.org/oma/group/KDMRDMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCI7", "url": "https://www.orthodb.org/?gene=A0A8V0YCI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001234192", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234192", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAPSGRRKRPRPAASIFPGSGTSPRGREGERRGSGSEGASQNQRALDDCKTLVQDFNTQVALYRELVISIGDVSVTCPSLHAEMHKTRTRGCEMAYQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPCAPPKILDTKVEESSEVPILEDTLSSPTDIQQHLWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLVSS", "length": 255, "header": "tr|A0A8V0YCI7-1|A0A8V0YCI7_CHICK Isoform 1 of Regulator of G protein signaling 7 binding protein OS=Gallus gallus OX=9031 GN=RGS7BP PE=3 SV=1 CANONICAL=A0A8V0YCI7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7/entry#A0A8V0YCI7-1", "sequence": { "sequence": "MSSAPSGRRKRPRPAASIFPGSGTSPRGREGERRGSGSEGASQNQRALDDCKTLVQDFNTQVALYRELVISIGDVSVTCPSLHAEMHKTRTRGCEMAYQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPCAPPKILDTKVEESSEVPILEDTLSSPTDIQQHLWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLVSS", "length": 255, "header": "tr|A0A8V0YCI7-1|A0A8V0YCI7_CHICK Isoform 1 of Regulator of G protein signaling 7 binding protein OS=Gallus gallus OX=9031 GN=RGS7BP PE=3 SV=1 CANONICAL=A0A8V0YCI7-1" }, "locus": { "chromosome": "Z", "start_pos": 20740530, "end_pos": 20706517, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023896.1", "url": "https://www.ensembl.org/id/ENSGALT00010023896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013656.1", "url": "https://www.ensembl.org/id/ENSGALP00010013656.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770874", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UPG6-1", "protein_name": "Regulator of G protein signaling 7 binding protein", "gene_name": "RGS7BP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKNLDCKIEESTETPALEDSSSSPIDTQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLVSS", "length": 257 }, "evidence": [ { "id": "A0A8V0YCI7", "url": "https://omabrowser.org/oma/group/A0A8V0YCI7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QLZ8-1", "protein_name": "Regulator of G-protein signaling 7-binding protein isoform X1", "gene_name": "Rgs7bp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASGGAKSLDSKIEENAETPALEDSSSSPLESQQQSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPMVRRRKRRFFGLCCLVSS", "length": 257 }, "evidence": [ { "id": "A0A8V0YCI7", "url": "https://omabrowser.org/oma/group/A0A8V0YCI7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q08BU8-1", "protein_name": "Regulator of G protein signaling 7-binding protein A", "gene_name": "rgs7bpa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSAPNGRKNRPRTAGTIFQIGGKAPSRESERRESSEALLAVSDCRMVVQEFNTLVALYRELVISIGEISADCPSLRAEMHKTRTKGCEMARTAHQNLSAISGPEDGEIHPEICRLFIQLQCCLEMYLTEMLKSVCLLGSLQLHRKGKHYLGATKLDSRKEDSSDIPILEDTSSTPPDCPHTYFLVATDIENIERDMTEMKNLLSKLRETMPLPLKNQDDSSLLNLAPYPMVRQRKRRFFGLCCLVSS", "length": 248 }, "evidence": [ { "id": "A0A8V0YCI7", "url": "https://omabrowser.org/oma/group/A0A8V0YCI7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08DH5-1", "protein_name": "Regulator of G protein signaling 7-binding protein", "gene_name": "RGS7BP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQTGDWERRGSGSESAHKSQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLREEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGSKSLDCKIEECAETPALEDSSPSPVDIQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLVSS", "length": 257 }, "evidence": [ { "id": "A0A8V0YCI7", "url": "https://omabrowser.org/oma/group/A0A8V0YCI7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5FVH8-1", "protein_name": "Regulator of G protein signaling 7-binding protein", "gene_name": "Rgs7bp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASGGAKSLDSKIEENAETPALEDSLSSPLDSQQQSWQVATDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPMVRRRKRRFFGLCCLVSS", "length": 257 }, "evidence": [ { "id": "A0A8V0YCI7", "url": "https://omabrowser.org/oma/group/A0A8V0YCI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6MZT1-1", "protein_name": "Regulator of G protein signaling 7-binding protein", "gene_name": "RGS7BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQVSTDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRRRKRRFFGLCCLISS", "length": 257 }, "evidence": [ { "id": "A0A8V0YCI7", "url": "https://omabrowser.org/oma/group/A0A8V0YCI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BQP9-1", "protein_name": "Regulator of G protein signaling 7-binding protein", "gene_name": "Rgs7bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQAHQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASGGAKNLDSKIEENAETPALEDSLSSPLESQQQCWQVATDIENTERDMREMKNLLSKLRETMPLPLKNQDDSSLLNLTPYPMVRRRKRRFFGLCCLVSS", "length": 257 }, "evidence": [ { "id": "A0A8V0YCI7", "url": "https://omabrowser.org/oma/group/A0A8V0YCI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" }, { "name": "regulation of postsynaptic membrane potential", "id": "GO:0060078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCJ7-1", "uniprot_ac": "A0A8V0YCJ7", "uniprot_id": "A0A8V0YCJ7_CHICK", "mass": { "chemical_mass": 35670.0, "monoisotopic_mass": 35670.0 }, "refseq": { "ac": "XP_040516551", "name": "GRB2-related adapter protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516551" }, "gene_names": [ { "name": "GRAP2", "type": "recommended", "evidence": [ { "id": "A0A8V0YCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7" } ] }, { "name": "GRAP2", "type": "synonym", "evidence": [ { "id": "XP_040516551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516551" } ] } ], "protein_names": [ { "name": "GRB2 related adaptor protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YCJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7/entry#names_and_taxonomy" } ] }, { "name": "GRB2-related adapter protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040516551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516551" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040516551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516551" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7", "locus": { "chromosome": "1", "start_pos": 50337802, "end_pos": 50378548, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013194", "url": "https://www.ensembl.org/id/ENSGALG00010013194" } ] } } ], "crossref": [ { "id": "A0A8V0YCJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012056", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012056", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11950", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11950", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770756", "url": "https://www.ncbi.nlm.nih.gov/gene/770756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770756", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770756", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VAKFDFM", "url": "https://omabrowser.org/oma/group/VAKFDFM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCJ7", "url": "https://www.orthodb.org/?gene=A0A8V0YCJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIZ3", "url": "https://www.orthodb.org/?gene=A0A8V0YIZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQT4", "url": "https://www.orthodb.org/?gene=A0A8V0YQT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQF3", "url": "https://www.orthodb.org/?gene=E1BQF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1433557", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433557", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-202433", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202433", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2424491", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2424491", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871796", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871809", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871809", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040516551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040516551", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQF3", "url": "https://www.uniprot.org/uniprotkb/E1BQF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQF3-1", "url": "https://www.uniprot.org/uniprotkb/E1BQF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTEEGSALPPTRRMEAIAKFDFTASGEDELSFQAGDILKILSSQEEWYKAELRSQEGYVPKNFIDFHVPPWFDEKISRHEAESILMNKGVGSFIVRASQNSHGDFSISVRHEDDVQHFKVMRDSKGNYYLWTEKFYSLNKLVDYYRTSTISRQKQILLRDDSREEKERRGGSLERMSRDGLHVGGAAAEAHSSMSKRYVDHPVPVLHQQQDRYGGSLDRKDALHGLRYHSQGSAAAMQRRHTDPLHQQTPRILWVRALYDFDAVEHDELGFRSGDIVEVLDNSNPSWWKGRLRGELGLFPANYVTPVLL", "length": 310, "header": "tr|A0A8V0YCJ7-1|A0A8V0YCJ7_CHICK Isoform 1 of GRB2 related adaptor protein 2 OS=Gallus gallus OX=9031 GN=GRAP2 PE=4 SV=1 CANONICAL=A0A8V0YCJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7/entry#A0A8V0YCJ7-1", "sequence": { "sequence": "MNTEEGSALPPTRRMEAIAKFDFTASGEDELSFQAGDILKILSSQEEWYKAELRSQEGYVPKNFIDFHVPPWFDEKISRHEAESILMNKGVGSFIVRASQNSHGDFSISVRHEDDVQHFKVMRDSKGNYYLWTEKFYSLNKLVDYYRTSTISRQKQILLRDDSREEKERRGGSLERMSRDGLHVGGAAAEAHSSMSKRYVDHPVPVLHQQQDRYGGSLDRKDALHGLRYHSQGSAAAMQRRHTDPLHQQTPRILWVRALYDFDAVEHDELGFRSGDIVEVLDNSNPSWWKGRLRGELGLFPANYVTPVLL", "length": 310, "header": "tr|A0A8V0YCJ7-1|A0A8V0YCJ7_CHICK Isoform 1 of GRB2 related adaptor protein 2 OS=Gallus gallus OX=9031 GN=GRAP2 PE=4 SV=1 CANONICAL=A0A8V0YCJ7-1" }, "locus": { "chromosome": "1", "start_pos": 50353178, "end_pos": 50339783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031666.1", "url": "https://www.ensembl.org/id/ENSGALT00010031666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018526.1", "url": "https://www.ensembl.org/id/ENSGALP00010018526.1" } ] } }, { "isoform_ac": "A0A8V0YIZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7/entry#A0A8V0YIZ3-1", "sequence": { "sequence": "MSSALPPTRRMEAIAKFDFTASGEDELSFQAGDILKILSSQEEWYKAELRSQEGYVPKNFIDFHVPPWFDEKISRHEAESILMNKGVGSFIVRASQNSHGDFSISVRHEDDVQHFKVMRDSKGNYYLWTEKFYSLNKLVDYYRTSTISRQKQILLRDDSREEKERRGGSLERMSRDGLHVGGAAAEAHSSMSKRYVDHPVPVLHQQQDRYGGSLDRKDALHGLRYHSQGSAAAMQRRHTDPLHQQTPRILWVRALYDFDAVEHDELGFRSGDIVEVLDNSNPSWWKGRLRGELGLFPANYVTPVLL", "length": 306, "header": "tr|A0A8V0YIZ3-1|A0A8V0YCJ7_CHICK Computationally mapped isoform of GRB2 related adaptor protein 2 OS=Gallus gallus OX=9031 GN=GRAP2 PE=4 SV=1 CANONICAL=A0A8V0YCJ7-1" }, "locus": { "chromosome": "1", "start_pos": 50355376, "end_pos": 50339783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031669.1", "url": "https://www.ensembl.org/id/ENSGALT00010031669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018528.1", "url": "https://www.ensembl.org/id/ENSGALP00010018528.1" } ] } }, { "isoform_ac": "A0A8V0YQT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7/entry#A0A8V0YQT4-1", "sequence": { "sequence": "MVKPFSPKWLHGLRPMLSTGAEGRRHEDDVQHFKVMRDSKGNYYLWTEKFYSLNKLVDYYRTSTISRQKQILLRDDSREEKERRGGSLERMSRDGLHVGGAAAEAHSSMSKRYVDHPVPVLHQQQDRYGGSLDRKDALHGLRYHSQGSAAAMQRRHTDPLHQQTPRILWVRALYDFDAVEHDELGFRSGDIVEVLDNSNPSWWKGRLRGELGLFPANYVTPVLL", "length": 224, "header": "tr|A0A8V0YQT4-1|A0A8V0YCJ7_CHICK Computationally mapped isoform of GRB2 related adaptor protein 2 OS=Gallus gallus OX=9031 GN=GRAP2 PE=4 SV=1 CANONICAL=A0A8V0YCJ7-1" }, "locus": { "chromosome": "1", "start_pos": 50378547, "end_pos": 50339783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031674.1", "url": "https://www.ensembl.org/id/ENSGALT00010031674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018532.1", "url": "https://www.ensembl.org/id/ENSGALP00010018532.1" } ] } }, { "isoform_ac": "E1BQF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7/entry#E1BQF3-1", "sequence": { "sequence": "MEAIAKFDFTASGEDELSFQAGDILKILSSQEEWYKAELRSQEGYVPKNFIDFHVPPWFDEKISRHEAESILMNKGVGSFIVRASQNSHGDFSISVRHEDDVQHFKVMRDSKGNYYLWTEKFYSLNKLVDYYRTSTISRQKQILLRDDSREEKERRGGSLERMSRDGLHVGGAAAEAHSSMSKRYVDHPVPVLHQQQDRYGGSLDRKDALHGLRYHSQGSAAAMQRRHTDPLHQQTPRILWVRALYDFDAVEHDELGFRSGDIVEVLDNSNPSWWKGRLRGELGLFPANYVTPVLL", "length": 296, "header": "tr|E1BQF3-1|E1BQF3_CHICK Computationally mapped isoform of GRB2 related adaptor protein 2 OS=Gallus gallus OX=9031 GN=GRAP2 PE=4 SV=4 CANONICAL=A0A8V0YCJ7-1" }, "locus": { "chromosome": "1", "start_pos": 50352486, "end_pos": 50339783, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031672.1", "url": "https://www.ensembl.org/id/ENSGALT00010031672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018531.1", "url": "https://www.ensembl.org/id/ENSGALP00010018531.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:770756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770756", "resource": "KEGG Pathway" }, { "id": "R-GGA-1433557", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433557", "resource": "Reactome", "description": "Signaling by SCF-KIT" }, { "id": "R-GGA-202433", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-202433", "resource": "Reactome", "description": "Generation of second messenger molecules" }, { "id": "R-GGA-2424491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2424491", "resource": "Reactome", "description": "DAP12 signaling" }, { "id": "R-GGA-2871796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871796", "resource": "Reactome", "description": "FCERI mediated MAPK activation" }, { "id": "R-GGA-2871809", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871809", "resource": "Reactome", "description": "FCERI mediated Ca+2 mobilization" }, { "id": "R-GGA-389356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389356", "resource": "Reactome", "description": "Co-stimulation by CD28" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BKA6-1", "protein_name": "Adapter protein GRID", "gene_name": "GRAP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAIAKFDFMASGEDELGFHAGDVLKILSNQGEWFKAELGSQEGYVPKNFIEIEFPEWFHEGLSRHQAESLLMGKELGCFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRKNSISKQKQIFLRDRTREEQGQRGNSLDRRSQGGHPLSGAVGEEIRPSMNRKPSDHPLLPPSQYPPAPLPAQQRYMPQHHFNQERRGASLDINDGPCGLGMSTEMNAALMHRRHTDPVQLQVAGRVRWARALYDFEALEDDELGFRCGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMIR", "length": 316 }, "evidence": [ { "id": "A0A8V0YCJ7", "url": "https://omabrowser.org/oma/group/A0A8V0YCJ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SRA1-1", "protein_name": "Adapter protein GRID", "gene_name": "GRAP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAIAKFDFIASGEDELSFQAGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAESLLMGKDVGCFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQIFLRDRTREDQGQRGNSLDRRSQGGLALSGAVGEEIRPAMNRKLSDHPPPPPSQYPPAPLPPQQRYLQQHLQQHHFHQDRRGGSLDINDGHCGLGMGSEMNAALMHRRHTDPVQLQVAGRVRWARALYDFEALEDDELGFQCGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR", "length": 320 }, "evidence": [ { "id": "A0A8V0YCJ7", "url": "https://omabrowser.org/oma/group/A0A8V0YCJ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75791-1", "protein_name": "GRB2-related adapter protein 2", "gene_name": "GRAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPPQQRYLQHHHFHQERRGGSLDINDGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR", "length": 330 }, "evidence": [ { "id": "A0A8V0YCJ7", "url": "https://omabrowser.org/oma/group/A0A8V0YCJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O89100-1", "protein_name": "GRB2-related adaptor protein 2", "gene_name": "Grap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEATAKFDFMASGEDELSFRTGDILKILSNQEEWLKAELGSQEGYVPKNFIDIEFPEWFHEGLSRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKLVDYYRTTSISKQKQVFLRDGTQDQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGPQQFHPHQQPSPQFTPGPQPPQQQRYLQHFHQDRRGGSLDINDGHCGLGSEVNATLMHRRHTDPVQLQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMMR", "length": 322 }, "evidence": [ { "id": "A0A8V0YCJ7", "url": "https://omabrowser.org/oma/group/A0A8V0YCJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCJ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCL7-1", "uniprot_ac": "A0A8V0YCL7", "uniprot_id": "A0A8V0YCL7_CHICK", "mass": { "chemical_mass": 12125.0, "monoisotopic_mass": 12125.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YCL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0YCL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QPPVSIHPRLLRSSLVALADSSCPLTELMERPGVGGGDNLKLRKTLECCFQKQQSALPPTCPPLTQDLCPGEMPKFTKKEVLDIPSLVSQPPALPLTSTCSSSRPRTVLVMF", "length": 112, "header": "tr|A0A8V0YCL7-1|A0A8V0YCL7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCL7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL7/entry#A0A8V0YCL7-1", "sequence": { "sequence": "QPPVSIHPRLLRSSLVALADSSCPLTELMERPGVGGGDNLKLRKTLECCFQKQQSALPPTCPPLTQDLCPGEMPKFTKKEVLDIPSLVSQPPALPLTSTCSSSRPRTVLVMF", "length": 112, "header": "tr|A0A8V0YCL7-1|A0A8V0YCL7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCL7-1" }, "locus": { "chromosome": "8", "start_pos": 7029624, "end_pos": 7027906, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024009.1", "url": "https://www.ensembl.org/id/ENSGALT00010024009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013691.1", "url": "https://www.ensembl.org/id/ENSGALP00010013691.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], 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[] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCN8-1", "uniprot_ac": "A0A8V0YCN8", "uniprot_id": "A0A8V0YCN8_CHICK", "mass": { "chemical_mass": 142457.0, "monoisotopic_mass": 142457.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ALF transcription elongation factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0YCN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8", "locus": {} } ], "crossref": [ { "id": "IPR007797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCN8", "url": "https://www.orthodb.org/?gene=A0A8V0YCN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI77", "url": "https://www.orthodb.org/?gene=A0A8V0YI77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL00", "url": "https://www.orthodb.org/?gene=A0A8V0YL00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQW5", "url": "https://www.orthodb.org/?gene=A0A8V0YQW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQX0", "url": "https://www.orthodb.org/?gene=A0A8V0YQX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10528:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10528:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLFDFFRDWDLEQQCHYEQDRNALKRKEWERRNQEVQQDEDLFASGFNLFGEPYKTNKGDALANRVQNTLGNYDEMKDLLTNHSNQSHLVGIPKNSVPQTPIEKNEQNFFSEQRNRVIPSHQISGHSSTSMPPPSSLSSNSALLHSHQSSRKSRTDWSRSGHNCSGTQQSQSSSQQSRTKHSSSHDLPQGRYEDLYNCQSEQHKGGGTEEANSMAASSHSRRHTHSKSAAGEHTYKENSHSKSPTELEFVGHGPGSPLPSTSLLSSNNGLSSQNFPPGLHCKSSMVQQKPTAYVRPMDGQDQVPNDSPELKPPIEIESGYGNQSFGTLLEGKVNTPSSKNKVPKLNIPPVGEAMGVVHWISNSVSGSRSAASCGSKVTLPNDSSSVEEILREMSHSWPPPLTAIHTPGKAEQTKFSIPSKVQDSQHLTSGYNVQKWSDPGGKVATKSVTQKSMLEDDLKLSSDEDDNEQAAEKTKLRNIPVNGLPVSVAHAAGLAHSSGGSGSSSESESSSESDSDSESSSSDSDCNEESRSATPEPEPPSTNKWQLDKWLNKVNPHNKTIISNQNEPHSETSSQPQNSQQAEGQNKGKLSNSLPPADSKDQAILSPIREKAKPRVAQKTPEAKSSKQKSPAHNEPTAQRTTGKKQPKKVERTSSVEEYNWPKPNNTSNTPKEKDTQEPPEQPKVRTKAAVGKTAPRKEPRTSTGLTSEKKKYRGPSKIVPKSREFIETDSSTSDSNTDQEESLQAKILPACSGPANSIKVKDPGSNILSVSSLTSNGSNTSIDQTSNDLEEQLFSPIPIVQNELLSPLREYEELKSLWVKIDLSLLSRIPGQEPFETISVKTEPREANVKHRRPSRESPTPAAEKTSAKSKRKHKSENLETFVETKKQRLEDPSASCLLPPCISPIPNHRLTSTKESSSNLVKKMAKKREEKLFPPPLSPLLDEPVHRRHSNDNSSFSQETSITNTCQTSSSSSSVSKHRKNENKSNPKGICEEETHNAPTANALLDTNHLETDIWSAMPTLSNGNSEPRRPKITFDDVLHNADYYMQEAKKLKHKADALLEKFGKAVNYADAALSFIECGNAMERDPLEAKSPYTMYSETVELIRYAMRLKNFTGSSATEGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKNSSKASQAPSPWGGNGKSTETPSPMPLSPSPVSSAGGSAGITGSSSAGTITIPQRIHHMAASHVNITNNVLRSYEHWDMADKLTKENKEFFVDLDTVMGPLTQHSSMTNLVRYVRQGLHWLHIEAHLL", "length": 1291, "header": "tr|A0A8V0YCN8-1|A0A8V0YCN8_CHICK Isoform 1 of ALF transcription elongation factor 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8/entry#A0A8V0YCN8-1", "sequence": { "sequence": "MDLFDFFRDWDLEQQCHYEQDRNALKRKEWERRNQEVQQDEDLFASGFNLFGEPYKTNKGDALANRVQNTLGNYDEMKDLLTNHSNQSHLVGIPKNSVPQTPIEKNEQNFFSEQRNRVIPSHQISGHSSTSMPPPSSLSSNSALLHSHQSSRKSRTDWSRSGHNCSGTQQSQSSSQQSRTKHSSSHDLPQGRYEDLYNCQSEQHKGGGTEEANSMAASSHSRRHTHSKSAAGEHTYKENSHSKSPTELEFVGHGPGSPLPSTSLLSSNNGLSSQNFPPGLHCKSSMVQQKPTAYVRPMDGQDQVPNDSPELKPPIEIESGYGNQSFGTLLEGKVNTPSSKNKVPKLNIPPVGEAMGVVHWISNSVSGSRSAASCGSKVTLPNDSSSVEEILREMSHSWPPPLTAIHTPGKAEQTKFSIPSKVQDSQHLTSGYNVQKWSDPGGKVATKSVTQKSMLEDDLKLSSDEDDNEQAAEKTKLRNIPVNGLPVSVAHAAGLAHSSGGSGSSSESESSSESDSDSESSSSDSDCNEESRSATPEPEPPSTNKWQLDKWLNKVNPHNKTIISNQNEPHSETSSQPQNSQQAEGQNKGKLSNSLPPADSKDQAILSPIREKAKPRVAQKTPEAKSSKQKSPAHNEPTAQRTTGKKQPKKVERTSSVEEYNWPKPNNTSNTPKEKDTQEPPEQPKVRTKAAVGKTAPRKEPRTSTGLTSEKKKYRGPSKIVPKSREFIETDSSTSDSNTDQEESLQAKILPACSGPANSIKVKDPGSNILSVSSLTSNGSNTSIDQTSNDLEEQLFSPIPIVQNELLSPLREYEELKSLWVKIDLSLLSRIPGQEPFETISVKTEPREANVKHRRPSRESPTPAAEKTSAKSKRKHKSENLETFVETKKQRLEDPSASCLLPPCISPIPNHRLTSTKESSSNLVKKMAKKREEKLFPPPLSPLLDEPVHRRHSNDNSSFSQETSITNTCQTSSSSSSVSKHRKNENKSNPKGICEEETHNAPTANALLDTNHLETDIWSAMPTLSNGNSEPRRPKITFDDVLHNADYYMQEAKKLKHKADALLEKFGKAVNYADAALSFIECGNAMERDPLEAKSPYTMYSETVELIRYAMRLKNFTGSSATEGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKNSSKASQAPSPWGGNGKSTETPSPMPLSPSPVSSAGGSAGITGSSSAGTITIPQRIHHMAASHVNITNNVLRSYEHWDMADKLTKENKEFFVDLDTVMGPLTQHSSMTNLVRYVRQGLHWLHIEAHLL", "length": 1291, "header": "tr|A0A8V0YCN8-1|A0A8V0YCN8_CHICK Isoform 1 of ALF transcription elongation factor 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCN8-1" }, "locus": { "chromosome": "4", "start_pos": 18441168, "end_pos": 18142642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031718.1", "url": "https://www.ensembl.org/id/ENSGALT00010031718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018566.1", "url": "https://www.ensembl.org/id/ENSGALP00010018566.1" } ] } }, { "isoform_ac": "A0A8V0YI77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8/entry#A0A8V0YI77-1", "sequence": { "sequence": "MDLFDFFRDWDLEQQCHYEQDRNALKRKEWERRNQEVQQDEDLFASGFNLFGEPYKTNKGDALANRVQNTLGNYDEMKDLLTNHSNQSHLVGIPKNSVPQTPIEKNEQNFFSEQRNRVIPSHQISGHSSTSMPPPSSLSSNSALLHSHQSSRKSRTDWSRSGHNCSGTQQSQSSSQQSRTKHSSSHDLPQGRYEDLYNCQSEQHKGGGTEEANSMAASSHSRRHTHSKSAAGEHTYKENSHSKSPTELEFVGHGPGSPLPSTSLLSSNNGLSSQNFPPGLHCKSSMVQQKPTAYVRPMDGQDQVPNDSPELKPPIEIESGYGNQSFGTLLEGKVNTPSSKNKVPKLNIPPVGEVTLPNDSSSVEEILREMSHSWPPPLTAIHTPGKAEQTKFSIPSKVQDSQHLTSGYNVQKWSDPGGKVATKSVTQKSMLEDDLKLSSDEDDNEQAAEKTKLRNIPVKKTGRPIAVPVGGHSGLPVSVAHAAGLAHSSGGSGSSSESESSSESDSDSESSSSDSDCNEESRSATPEPEPPSTNKWQLDKWLNKVNPHNKTIISNQNEPHSETSSQPQNSQQAEGQNKGKLSNSLPPADSKDQAILSPIREKAKPRVAQKTPEAKSSKQKSPAHNEPTAQRTTGKKQPKKVERTSSVEEYNWPKPNNTSNTPKEKDTQEPPEQPKVRTKAAVGKTAPRKEPRTSTGLTSEKKKYRGPSKIVPKSREFIETDSSTSDSNTDQEESLQAKILPACSGPANSIKVKDPGSNILSVSSLTSNGSNTSIDQTSNDLEEQLFSPIPIVQNELLSPLREYEELKSLWVKIDLSLLSRIPGQEPFETISVKTEPREANVKHRRPSRESPTPAAEKTSAKSKRKHKSENLETFVETKKQRLEDPSASCLLPPCISPIPNHRLTSTKESSSNLVKKMAKKREEKLFPPPLSPLLDEPVHRRHSNDNSSFSQETSITNTCQTSSSSSSVSKHRKNENKSNPKGICEEETHNAPTANALLDTNHLETDIWSAMPTLSNGNSEPRRPKITFDDVLHNADYYMQEAKKLKHKADALLEKFGKAVNYADAALSFIECGNAMERDPLEAKSPYTMYSETVELIRYAMRLKNFTGSSATEGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKNSSKASQAPSPWGGNGKSTETPSPMPLSPSPVSSAGGSAGITGSSSAGTITIPQRIHHMAASHVNITNNVLRSYEHWDMADKLTKENKEFFVDLDTVMGPLTQHSSMTNLVRYVRQGLHWLHIEAHLL", "length": 1281, "header": "tr|A0A8V0YI77-1|A0A8V0YCN8_CHICK Computationally mapped isoform of ALF transcription elongation factor 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCN8-1" }, "locus": { "chromosome": "4", "start_pos": 18441168, "end_pos": 18142642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031702.1", "url": "https://www.ensembl.org/id/ENSGALT00010031702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018550.1", "url": "https://www.ensembl.org/id/ENSGALP00010018550.1" } ] } }, { "isoform_ac": "A0A8V0YL00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8/entry#A0A8V0YL00-1", "sequence": { "sequence": 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"length": 1274, "header": "tr|A0A8V0YL00-1|A0A8V0YCN8_CHICK Computationally mapped isoform of ALF transcription elongation factor 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCN8-1" }, "locus": { "chromosome": "4", "start_pos": 18441168, "end_pos": 18142642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031706.1", "url": "https://www.ensembl.org/id/ENSGALT00010031706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018554.1", "url": "https://www.ensembl.org/id/ENSGALP00010018554.1" } ] } }, { "isoform_ac": "A0A8V0YQW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8/entry#A0A8V0YQW5-1", "sequence": { "sequence": "MDLFDFFRDWDLEQQCHYEQDRNALKRKEWERRNQEVQQDEDLFASGFNLFGEPYKTNKGDALANRVQNTLGNYDEMKDLLTNHSNQSHLVGIPKNSVPQTPIEKNEQNFFSEQRNRVIPSHQISGHSSTSMPPPSSLSSNSALLHSHQSSRKSRTDWSRSGHNCSGTQQSQSSSQQSRTKHSSSHDLPQGRYEDLYNCQSEQHKGGGTEEANSMAASSHSRRHTHSKSAAGEHTYKENSHSKSPTELEFVGHGPGSPLPSTSLLSSNNGLSSQNFPPGLHCKSSMVQQKPTAYVRPMDGQDQVPNDSPELKPPIEIESGYGNQSFGTLLEGKVNTPSSKNKVPKLNIPPVGEEMSHSWPPPLTAIHTPGKAEQTKFSIPSKVQDSQHLTSGYNVQKWSDPGGKVATKSVTQKSMLEDDLKLSSDEDDNEQAAEKTKLRNIPVNGLPVSVAHAAGLAHSSGGSGSSSESESSSESDSDSESSSSDSDCNEESRSATPEPEPPSTNKWQLDKWLNKVNPHNKTIISNQNEPHSETSSQPQNSQQAEGQNKGKLSNSLPPADSKDQAILSPIREKAKPRVAQKTPEAKSSKQKSPAHNEPTAQRTTGKKQPKKVERTSSVEEYNWPKPNNTSNTPKEKDTQEPPEQPKVRTKAAVGKTAPRKEPRTSTGLTSEKKKYRGPSKIVPKSREFIETDSSTSDSNTDQEESLQAKILPACSGPANSIKVKDPGSNILSVSSLTSNGSNTSIDQTSNDLEEQLFSPIPIVQNELLSPLREYEELKSLWVKIDLSLLSRIPGQEPFETISVKTEPREANVKHRRPSRESPTPAAEKTSAKSKRKHKSENLETFVETKKQRLEDPSASCLLPPCISPIPNHRLTSTKESSSNLVKKMAKKREEKLFPPPLSPLLDEPVHRRHSNDNSSFSQETSITNTCQTSSSSSSVSKHRKNENKSNPKGICEEETHNAPTANALLDTNHLETDIWSAMPTLSNGNSEPRRPKITFDDVLHNADYYMQEAKKLKHKADALLEKFGKAVNYADAALSFIECGNAMERDPLEAKSPYTMYSETVELIRYAMRLKNFTGSSATEGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKNSSKASQAPSPWGGNGKSTETPSPMPLSPSPVSSAGGSAGITGSSSAGTITIPQRIHHMAASHVNITNNVLRSYEHWDMADKLTKENKEFFVDLDTVMGPLTQHSSMTNLVRYVRQGLHWLHIEAHLL", "length": 1252, "header": "tr|A0A8V0YQW5-1|A0A8V0YCN8_CHICK Computationally mapped isoform of ALF transcription elongation factor 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCN8-1" }, "locus": { "chromosome": "4", "start_pos": 18441168, "end_pos": 18142642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031709.1", "url": "https://www.ensembl.org/id/ENSGALT00010031709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018557.1", "url": "https://www.ensembl.org/id/ENSGALP00010018557.1" } ] } }, { "isoform_ac": "A0A8V0YQX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8/entry#A0A8V0YQX0-1", "sequence": { "sequence": "MDLFDFFRDWDLEQQCHYEQDRNALKRKEWERRNQEVQQDEDLFASGFNLFGEPYKTNKGDALANRVQNTLGNYDEMKDLLTNHSNQSHLVGIPKNSVPQTPIEKNEQNFFSEQRNRVIPSHQISGHSSTSMPPPSSLSSNSALLHSHQSSRKSRTDWSRSGHNCSGTQQSQSSSQQSRTKHSSSHDLPQGRYEDLYNCQSEQHKGGGTEEANSMAASSHSRRHTHSKSAAGEHTYKENSHSKSPTELEFVGHGPGSPLPSTSLLSSNNGLSSQNFPPGLHCKSSMVQQKPTAYVRPMDGQDQVPNDSPELKPPIEIESGYGNQSFGTLLEGKVNTPSSKNKVPKLNIPPVGEVTLPNDSSSVEEILRDSQHLTSGYNVQKWSDPGGKVATKSVTQKSMLEDDLKLSSDEDDNEQAAEKTKLRNIPVNGLPVSVAHAAGLAHSSGGSGSSSESESSSESDSDSESSSSDSDCNEESRSATPEPEPPSTNKWQLDKWLNKVNPHNKTIISNQNEPHSETSSQPQNSQQAEGQNKGKLSNSLPPADSKDQAILSPIREKAKPRVAQKTPEAKSSKQKSPAHNEPTAQRTTGKKQPKKVERTSSVEEYNWPKPNNTSNTPKEKDTQEPPEQPKVRTKAAVGKTAPRKEPRTSTGLTSEKKKYRGPSKIVPKSREFIETDSSTSDSNTDQEESLQAKILPACSGPANSIKVKDPGSNILSVSSLTSNGSNTSIDQTSNDLEEQLFSPIPIVQNELLSPLREYEELKSLWVKIDLSLLSRIPGQEPFETISVKTEPREANVKHRRPSRESPTPAAEKTSAKSKRKHKSENLETFVETKKQRLEDPSASCLLPPCISPIPNHRLTSTKESSSNLVKKMAKKREEKLFPPPLSPLLDEPVHRRHSNDNSSFSQETSITNTCQTSSSSSSVSKHRKNENKSNPKGICEEETHNAPTANALLDTNHLETDIWSAMPTLSNGNSEPRRPKITFDDVLHNADYYMQEAKKLKHKADALLEKFGKAVNYADAALSFIECGNAMERDPLEAKSPYTMYSETVELIRYAMRLKNFTGSSATEGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKNSSKASQAPSPWGGNGKSTETPSPMPLSPSPVSSAGGSAGITGSSSAGTITIPQRIHHMAASHVNITNNVLRSYEHWDMADKLTKENKEFFVDLDTVMGPLTQHSSMTNLVRYVRQGLHWLHIEAHLL", "length": 1236, "header": "tr|A0A8V0YQX0-1|A0A8V0YCN8_CHICK Computationally mapped isoform of ALF transcription elongation factor 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0YCN8-1" }, "locus": { "chromosome": "4", "start_pos": 18441168, "end_pos": 18142642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031714.1", "url": "https://www.ensembl.org/id/ENSGALT00010031714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018562.1", "url": "https://www.ensembl.org/id/ENSGALP00010018562.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 862, "start_aa": "Thr", "end_pos": 862, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr862", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" }, { "name": "nervous system process", "id": "GO:0050877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" }, { "name": "DNA-templated transcription elongation", "id": "GO:0006354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006354", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G-quadruplex RNA binding", "id": "GO:0002151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1164, "end_pos": 1166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0YCN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCN8" }, { "id": "PF18876", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18876" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AF4/FMR2 C-terminal homology", "eco_id": "ECO_0000259", "start_pos": 1028, "end_pos": 1290, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 862 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0YCP7-1", "uniprot_ac": "A0A8V0YCP7", "uniprot_id": "A0A8V0YCP7_CHICK", "mass": { "chemical_mass": 11794.0, "monoisotopic_mass": 11794.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0YCP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCP7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCP7", "locus": {} } ], "crossref": [ { "id": "A0A8V0YCP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0YCP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YCP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "REPTPLHPSRDSTLACPLYFSCYQLRRGLQEMNKASVKIQAAWRGYQVRRELDEMNKAAVKIQAAYRSHRTPGYPYATLQPKAHRARSQLSRHRTALSQQAQ", "length": 102, "header": "tr|A0A8V0YCP7-1|A0A8V0YCP7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCP7/entry#A0A8V0YCP7-1", "sequence": { "sequence": "REPTPLHPSRDSTLACPLYFSCYQLRRGLQEMNKASVKIQAAWRGYQVRRELDEMNKAAVKIQAAYRSHRTPGYPYATLQPKAHRARSQLSRHRTALSQQAQ", "length": 102, "header": "tr|A0A8V0YCP7-1|A0A8V0YCP7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0YCP7-1" }, "locus": { "chromosome": "Z", "start_pos": 54318954, "end_pos": 54316612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028359.1", "url": "https://www.ensembl.org/id/ENSGALT00010028359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016252.1", "url": "https://www.ensembl.org/id/ENSGALP00010016252.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFZ0-1", "uniprot_ac": "A0A8V1AFZ0", "uniprot_id": "A0A8V1AFZ0_CHICK", "mass": { "chemical_mass": 406869.0, "monoisotopic_mass": 406869.0 }, "refseq": {}, "gene_names": [ { "name": "BSN", "type": "recommended", "evidence": [ { "id": "A0A8V1AFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ] } ], "protein_names": [ { "name": "Bassoon presynaptic cytomatrix protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BSN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0", "locus": { "chromosome": "12", "start_pos": 2660151, "end_pos": 2706080, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027313", "url": "https://www.ensembl.org/id/ENSGALG00010027313" } ] } } ], "crossref": [ { "id": "cd15773", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15773", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15775", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15775", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3L7", "url": "https://www.orthodb.org/?gene=A0A8V1A3L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8I1", "url": "https://www.orthodb.org/?gene=A0A8V1A8I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFY5", "url": "https://www.orthodb.org/?gene=A0A8V1AFY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFZ0", "url": "https://www.orthodb.org/?gene=A0A8V1AFZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14113:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14113:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05715", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05715", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A3L7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTESQRGCDGRDLPAPPVPWAGCPPAQVPPWPGAPPNPSLPLCLLMLDHAAGQRSAAPSLAQGSESPREMRGRGQAEGPRRTLQVDPHGQRAGRSPSASPERGSTPTSPYSLPQIAPLPSSTLCPICKTTELTSAPSQPNFNACTQCHSKVCNQCGFNPNPHLTEVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPSPSPSHSPAKLPAGQEKTPAPTQPSARPGTAATAVPPPEPPRAQSAALQREQHGQPKAAAPPEAARASLQHQQAKPSSSEQRKALGDPKPAALAPGAGAAEQPQEGLTGKLFGFGASLLTQASTLMSVQPEAPAPSPQASGKVPPKIVFSDASKEAGPKAGGAQGWVGAAKASKAEPGVKPKEVPKARVLCPLCKAEINVGSAEPPNYNACTSCRQQVCNMCGFNPAPHLVEKNEWLCLNCQTQRLLEGSLADPAPMPLPAPKQPTSGSPRHQPTAATQRAAAPAEPAAPPKQQPSPARSLWAPEQSRAPSPAPEKKPPVPAEEKPLPKAAPEPSVPVPKGKSVSPKPEGESKEGRAAPEAQRAKELEDAGKPYPPDLSRSPQSLSDTGYSSDGISSSQSEITGLVQQEEEKLSGTGLAGQSPPSPSELTKLESSMRPLLEVRGRSSGNGSGPRYLSITPEAFDSDEELEDILEEDEDSLEWENQREQRESVESSDEFGSKLRHDYVEDSSEGGFSPVPGRPKGREEVADEEFMRRQILEMSAEEDNLEEEEEEGYGRSKYSVQKAEAEKGKEPSPAKRRLPHGPGGLYKEERKELEAAESEDMSTTQGGLRRFKTIELNSTTGYGREMEVSQEADAGLEREPELEMESLTGSPEERSRGEYSSTLPATTPSYTSGTSPTSISSLEEDSDSSPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIDSEAESFDAVTSKLYKSGSEYNLPTFMSLYSPTEKVESVQPASKPLKSAEEAYEEMMRKAEMMQKQQVQQAQQDVSYGSTYQQVGYRSTEGQNGFQYQYADEYGYDSGPTRSSQPDYSSSLSKPGAVYEEILQTSQSIARMHQSSSFDLALEKGDKKKGQEEPYQEKHFLNAESAYAELMKQNGGPLTPGTSPTQLSAPVSFSTSEGSKVVPDVRVTQHFAKEGQDLAKLQSTPSAPSPTSKPITAPYTYSKGTSAVTTAAASPASTPRIYSSAEAASTPARSYSPAKSTISYGSQTEDITRSKVGVETSVQTAREKLQAVSDGKPPPAKTYSFFKSSSPPLSPTSPTQSPTHAAPRAAAPSGPTAKSTAEFSTQTQSPLLAYDVPTTTGPSASSPMVAQGTQTPHRAGSPRLTRQQSSQDAPFMLITLAADAASQTKPPSSSASPVSSPTRISRQVIAHGYGQEPEQPLATFIRAQHVKDPAQKVPVTSGPDGITGLYSWGALPAENISLCRISSIPGTSRVEPGPKVPSSSAVDLRTALKSAPIIITDQGMDLTSLATEARKYCLTLDQIPSRQSTAIQPLIINLNAQEQPHAIIAASSTTSLAIASPMLISQPKQPVVYGDPFQSRMDFGQGAGSPVCLAQVKQVEQGVQTGAGRASGTAVPAPTSKPEPPAPPQAKFSRYSLPSQMVKKDVLITQTSVAHSVSGLQQPFQQEQGSELYRAVPVELKTQSPLLALGGKKSQVMMVQVEDVAAGPVTKVLKEEPPANVLDLTGVKAESQVACCDVVYKFPFGSSCTGAFNPTSKVPEKKAADTVPSRKASGPLYGSREPEMPETFPYREQPAPALYEENKFYPTGAFGRLYSSMSDTNLSEIGMNYYPPKGDQPFHEAAVDLSTMKHSYSIGFAEGGYLGQGLQYGSFSDLRQPADLLGHPLPMRRYSSASNIYSDYRYSPRGDLASFQESSLAHYSATTAREISRMCAALNSMDHQYGARHANGPDTMSYGPGGGGLPAQPGGAAAPKPSGMFNPSVPETRQGFSGLAQYNVPGVRLGAVRQMFPSSATVRAADGMIYSTINTPIASTLPITTQPASVLRPMLRGLYRPYGPPGMAAVPLASLARVPVVAPRVPLAPQGLYRYPAPSRLPASSLMETPVYLGKAVSAAPGTGPAAKAPAAPATGVQRAEVSGAAPRTEPPAAGSKEGGQAAPAPKLASESVQREEREREEERQRKQQEHVLQLERERVELEKLRQLRLQEELERERAELQRHREKEQLLVQRELQELQCIKQQVLQQQQEERHAQLALQREQLAQQRLQLEHIHQLQHQLQQQLEEQKRQKTIFPAAGAEPTSRPSEGPAEVPRGPMHNGHGWTPAGQVLPGGPEGAGGPRYPAPQRPLSSSASDMSLQAEESWEPGRGIKKRNSMPRLRDAYEKETVRKTADSSVQTDEEDGEERYMLSRRRRSRRSTDCSVQTDEEDSGEWEQPVRRRRSRPSRHADASTEGKADGTARGVASVGIQTISDCSVQTEPDQLLRVSPSIHITTHDPRVEIIKYISAPEKTQRGESLACQTEPEPPPQPGIVVPQLTVPTTITPYSTNMQMVSTGPLDPHAVRQQTLGKFEKKKPDPLEIGYQSHLPADSLSQLVTRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFTDSAQRQQTLPRPIKTMQRSLSDPKPISPTSEEASKDRFSLYQHPLLPGTQVRAPLARKVKRTLPSPPPEEPHVALGSPATQQLYLGSLAPKAPAAAPVTKASLLKELDRDLKLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLLKDRGTRDHPYLRGLADRRDYLSDSELHSLRLATYDSTGLRPAPTAQYPDFTAASYGAYPYAAPPGPPAFPATRPQPPQFPTASTTQDGLPPAPLPAFASPATFPAPGTAYPELSAPAQPGFRPQNPYQAQGTFAGTASVPAAQPALYQSPSDAHQKPRQTSLAELEQKIPTNYEVISAATSSSAVPDVTLGAAAVSSSYEQYKAPEARLADRTGVTQGPSASFSSESLYTSLEQNIPRNYVMIEDISELTKESPAVDGQKVEPVGTGANGRHGKEKSELLDAEGPSRPCCYSKAEEESEEDIYDHHGPDHRGKNSYHRESNGRVSGSSAGSSYYYGDSEYRHSSRADKHGSGMALPKHSSKNLAPAVVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYAVTTSVSSSNVASRAKKLQDEITYGLKKNVYEQQKYYGVSSRDLVDEEERVYSSSGRTRSSGYGLEKSSGRDAGGRSKSFEREGVERSQKGSSKPSSLGMSQSRGRAPVRTQPSEEESPISPLGKSVGGSRSMGGPGPQSAGDPCSQFCSSHSLPDVQEHIKDVPRNHSYKHEEGYGMDDSHCVVSDSEAYHLGQEETDWFDKPREARSERVRHYGGHSSSQKRPPAKHTYHDYDEPPDEDPWQHDDYPQHREHRHHGDYGRHAASSRHDEQPRRSAKQHPRESGRHEPRGHTTPAAAKKAQQPEPRASAPYGPGASEYAPPSRHHGAEPQKVPKTPQPHGAPSPAQKPEPSAPAQQAAGRQPQAGQQAARQQPAARQGAQPAGTAQPRAQGPAAARPAQQQPGTGQPTGKAAATLHAQPGGHPAPQVSPGLLRPLAAAGEGLGTGACAAPGAHGRGHPYAPDSFGVWSLAPAVLGGCPPTGQPGAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFTSFW", "length": 3775, "header": "tr|A0A8V1AFZ0-1|A0A8V1AFZ0_CHICK Isoform 1 of Bassoon presynaptic cytomatrix protein OS=Gallus gallus OX=9031 GN=BSN PE=4 SV=1 CANONICAL=A0A8V1AFZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A3L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0/entry#A0A8V1A3L7-1", "sequence": { "sequence": "VCRRTRRTARSGTYGTARGVASVGIQTISDCSVQTEPDQLLRVSPSIHITTHDPRVEIIKYISAPEKTQRGESLACQTEPEPPPQPGIMVSTGPLDPHAKKKPDPLEIGYQSHLPADSLSQLVTRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFTDSAQRQQTLPRPIKTMQRSLSDPKPISPTSEEASKDRFSLYQHPLLPGTQVGTLQSSPLARKVKRTLPSPPPEEPHVALGSPATQQLYLGSLAPKAPAAAPVTKASLLKELDRDLKLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLLKDRGTRDHPYLRGLADRRDYLSDSELHSLRLATYDSTGLRPAPTAQYPDFTAASYGAYPYAAPPGPPAFPATQLSAPAQPGFRPQNPYQAQGTFAGTASVPAAQPALYQSPSDAHQKPRQTSLAELEQKIPTNYEVISAATSSSAVPDVTLGAAAVSSSYEQYKAPEARLADRTGVTQGPSASFSSESLYTSLEQNIPRNYVMIEDISELTKESPAVDGQKVEPVGTGANGRHGKEKSELLDAEGPSRPCCYSKAEEESEEDIYDHHGPDHRGKNSYHRESNGRVSGSSAGSSYYYGDSEYRHSSRADKHGSGMALPKHSSKNLAPAVVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYAVTTSVSSSNVASRAKKLQDEITYGLKKNVYEQQKYYGVSSRDLVDEEERVYSSSGRTRSSGYGLEKSSGRDAGGRSKSFEREGVERSQKGSSKPSSLGMSQSRGRAPVRTQPSEEESPISPLGKSVGGSRSMGGPGPQSAGDPCSQFCSSHSLPDVQEHIKDVPRNHSYKHEEGYGMDDSHCVLLAFSCLIAWLQPGLRSRLRSERLTVVCFWFLKPIIWVRRRQTGLISPGKRGQRE", "length": 930, "header": "tr|A0A8V1A3L7-1|A0A8V1A3L7_CHICK Computationally mapped isoform of Bassoon presynaptic cytomatrix protein OS=Gallus gallus OX=9031 GN=BSN PE=4 SV=1 CANONICAL=A0A8V1AFZ0-1" }, "locus": { "chromosome": "12", "start_pos": 2666019, "end_pos": 2661631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066209.1", "url": "https://www.ensembl.org/id/ENSGALT00010066209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040475.1", "url": "https://www.ensembl.org/id/ENSGALP00010040475.1" } ] } }, { "isoform_ac": "A0A8V1A8I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0/entry#A0A8V1A8I1-1", "sequence": { "sequence": "MTESQRGCDGRDLPAPPVPWAGCPPAQVPPWPGAPPNPSLPLCLLMLDHAAGQRSAAPSLAQGSESPREMRGRGQAEGPRRTLQVDPHGQRAGRSPSASPERGSTPTSPYSLPQIAPLPSSTLCPICKTTELTSAPSQPNFNACTQCHSKVCNQCGFNPNPHLTEKNEWLCLNCQTQRLLEGSLADPAPMPLPAPKQPTSGSPRHQPTAATQRAAAPAEPAAPPKQQPSPARSLWAPEQSRAPSPAPEKKPPVPAEEKPLPKAAPEPSVPVPKGKSVSPKPEGESKEGRAAPEAQRAKELEDAGKPYPPDLSRSPQSLSDTGYSSDGISSSQSEITGLVQQEEEKLSGTGLAGQSPPSPSELTKLESSMRPLLEVRGRSSGNGSGPRYLSITPEAFDSDEELEDILEEDEDSLEWENQREQRESVESSDEFGSKLRHDYVEDSSEGGFSPVPGRPKGREEVADEEFMRRQILEMSAEEDNLEEEEEEGYGRSKYSVQKAEAEKGKEPSPAKRRLPHGPGGLYKEERKELEAAESEDMSTTQGGLRRFKTIELNSTTGYGREMEVSQEADAGLEREPELEMESLTGSPEERSRGEYSSTLPATTPSYTSGTSPTSISSLEEDSDSSPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIDSEAESFDAVTSKLYKSGSEYNLPTFMSLYSPTEKVESVQPASKPLKSAEEAYEEMMRKAEMMQKQQVQQAQQDVSYGSTYQQVGYRSTEGQNGFQYQYADEYGYDSGPTRSSQPDYSSSLSKPGAVYEEILQTSQSIARMHQSSSFDLALEKGDKKKGQEEPYQEKHFLNAESAYAELMKQNGGPLTPGTSPTQLSAPVSFSTSEGSKVVPDVRVTQHFAKEGQDLAKLQSTPSAPSPTSKPITAPYTYSKGTSAVTTAAASPASTPRIYSSAEAASTPARSYSPAKSTISYGSQTEDITRSKVGVETSVQTAREKLQAVSDGKPPPAKTYSFFKSSSPPLSPTSPTQSPTHAAPRAAAPSGPTAKSTAEFSTQTQSPLLAYDVPTTTGPSASSPMVAQGTQTPHRAGSPRLTRQQSSQDAPFMLITLAADAASQTKPPSSSASPVSSPTRISRQVIAHGYGQEPEQPLATFIRAQHVKDPAQKVPVTSGPDGITGLYSWGALPAENISLCRISSIPGTSRVEPGPKVPSSSAVDLRTALKSAPIIITDQGMDLTSLATEARKYCLTLDQIPSRQSTAIQPLIINLNAQEQPHAIIAASSTTSLAIASPMLISQPKQPVVYGDPFQSRMDFGQGAGSPVCLAQVKQVEQGVQTGAGRASGTAVPAPTSKPEPPAPPQAKFSRYSLPSQMVKKDVLITQTSVAHSVSGLQQPFQQEQGSELYRAVPVELKTQSPLLALGGKKSQVMMVQVEDVAAGPVTKVLKEEPPANVLDLTGVKAESQVACCDVVYKFPFGSSCTGAFNPTSKVPEKKAADTVPSRKASGPLYGSREPEMPETFPYREQPAPALYEENKFYPTGAFGRLYSSMSDTNLSEIGMNYYPPKGDQPFHEAAVDLSTMKHSYSIGFAEGGYLGQGLQYGSFSDLRQPADLLGHPLPMRRYSSASNIYSDYRYSPRGDLASFQESSLAHYSATTAREISRMCAALNSMDHQYGARHANGPDTMSYGPGGGGLPAQPGGAAAPKPSGMFNPSVPETRQGFSGLAQYNVPGVRLGAVRQMFPSSATVRAADGMIYSTINTPIASTLPITTQPASVLRPMLRGLYRPYGPPGMAAVPLASLARVPVVAPRVPLAPQGLYRYPAPSRLPASSLMETPVYLGKAVSAAPGTGPAAKAPAAPATGVQRAEVSGAAPRTEPPAAGSKEGGQAAPAPKLASESVQREEREREEERQRKQQEHVLQLERERVELEKLRQLRLQEELERERAELQRHREKEQLLVQRELQELQCIKQQVLQQQQEERHAQLALQREQLAQQRLQLEHIHQLQHQLQQQLEEQKRQKTIFPAAGAEPTSRPSEGPAEVPRGPMHNGHGWTPAGQVLPGGPEGAGGPRYPAPQRPLSSSASDMSLQAEESWEPGRGIKKRNSMPRLRDAYEKETVRKTADSSVQTDEEDGEERYMLSRRRRSRRSTDCSVQTDEEDSGEWEQPVRRRRSRPSRHADASTEGKADGTARGVASVGIQTISDCSVQTEPDQLLRVSPSIHITTHDPRVEIIKYISAPEKTQRGESLACQTEPEPPPQPGIVVPQLTVPTTITPYSTNMQMVSTGPLDPHAVRQQTLGKFEKKKPDPLEIGYQSHLPADSLSQLVTRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFTDSAQRQQTLPRPIKTMQRSLSDPKPISPTSEEASKDRFSLYQHPLLPGTQVRAPLARKVKRTLPSPPPEEPHVALGSPATQQLYLGSLAPKAPAAAPVTKASLLKELDRDLKLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLLKDRGTRDHPYLRGLADRRDYLSDSELHSLRLATYDSTGLRPAPTAQYPDFTAASYGAYPYAAPPGPPAFPATRPQPPQFPTASTTQDGLPPAPLPAFASPATFPAPGTAYPELSAPAQPGFRPQNPYQAQGTFAGTASVPAAQPALYQSPSDAHQKPRQTSLAELEQKIPTNYEVISAATSSSAVPDVTLGAAAVSSSYEQYKAPEARLADRTGVTQGPSASFSSESLYTSLEQNIPRNYVMIEDISELTKESPAVDGQKVEPVGTGANGRHGKEKSELLDAEGPSRPCCYSKAEEESEEDIYDHHGPDHRGKNSYHRESNGRVSGSSAGSSYYYGDSEYRHSSRADKHGSGMALPKHSSKNLAPAVVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYAVTTSVSSSNVASRAKKLQDEITYGLKKNVYEQQKYYGVSSRDLVDEEERVYSSSGRTRSSGYGLEKSSGRDAGGRSKSFEREGVERSQKGSSKPSSLGMSQSRGRAPVRTQPSEEESPISPLGKSVGGSRSMGGPGPQSAGDPCSQFCSSHSLPDVQEHIKDVPRNHSYKHEEGYGMDDSHCVVSDSEAYHLGQEETDWFDKPREARSERVRHYGGHSSSQKRPPAKHTYHDYDEPPDEDPWQHDDYPQHREHRHHGDYGRHAASSRHDEQPRRSAKQHPRESGRHEPRGHTTPAAAKKAQQPEPRASAPYGPGASEYAPPSRHHGAEPQKVPKTPQPHGAPSPAQKPEPSAPAQQAAGRQPQAGQQAARQQPAARQGAQPAGTAQPRAQGPAAARPAQQQPGTGQPTGKAAATLHAQPGGHPAPQVSPGLLRPLAAAGEGLGTGACAAPGAHGRGHPYAPDSFGVWSLAPAVLGGCPPTGQPGAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFTSFW", "length": 3509, "header": "tr|A0A8V1A8I1-1|A0A8V1A8I1_CHICK Computationally mapped isoform of Bassoon presynaptic cytomatrix protein OS=Gallus gallus OX=9031 GN=BSN PE=4 SV=1 CANONICAL=A0A8V1AFZ0-1" }, "locus": { "chromosome": "12", "start_pos": 2706080, "end_pos": 2660154, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066216.1", "url": "https://www.ensembl.org/id/ENSGALT00010066216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040482.1", "url": "https://www.ensembl.org/id/ENSGALP00010040482.1" } ] } }, { "isoform_ac": "A0A8V1AFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0/entry#A0A8V1AFY5-1", "sequence": { "sequence": "METPVYLGKAVSAAPGTGPAAKAPAAPATGVQRAEVSGAAPRTEPPAAGSKEGGQAAPAPKLASESVQREEREREEERQRKQQEHVLQLERERVELEKLRQLRLQEELERERAELQRHREKEQLLVQRELQELQCIKQQVLQQQQEERHAQLALQREQLAQQRLQLEHIHQLQHQLQQQLEEQKRQKTIFPAAGAEPTSRPSEGPAEVPRGPMHNGHGWTPAGQVLPGGPEGAGGPRYPAPQRPLSSSASDMSLQAEESWEPGRGIKKRNSMPRLRDAYEKETVRKTADSSVQTDEEDGEERYMLSRRRRSRRSTDCSVQTDEEDSGEWEQPVRRRRSRPSRHADASTEGKADGTARGVASVGIQTISDCSVQTEPDQLLRVSPSIHITTHDPRVEIIKYISAPEKTQRGESLACQTEPEPPPQPGIVVPQLTTLGKFEKKKPDPLEIGYQSHLPADSLSQLVTRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFTDSAQRQQTLPRPIKTMQRSLSDPKPISPTSEEASKDRFSLYQHPLLPGTQVGTLQSSPLARKVKRTLPSPPPEEPHVALGSPATQQLYLGSLAPKAPAAAPVTKASLLKELDRDLKLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLLKDRGTRDHPYLRGLADRRDYLSDSELHSLRLATYDSTGLRPAPTAQYPDFTAASYGAYPYAAPPGPPAFPATQLSAPAQPGFRPQNPYQAQGTFAGTASVPAAQPALYQSPSDAHQKPRQTSLAELEQKIPTNYEVISAATSSSAVPDVTLGAAAVSSSYEQYKAPEARLADRTGVTQGPSASFSSESLYTSLEQNIPRNYVMIEDISELTKESPAVDGQKVEPVGTGANGRHGKEKSELLDAEGPSRPCCYSKAEEESEEDIYDHHGPDHRGKNSYHRESNGRVSGSSAGSSYYYGDSEYRHSSRADKHGSGMALPKHSSKNLAPAVVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYAVTTSVSSSNVASRAKKLQDEITYGLKKNVYEQQKYYGVSSRDLVDEEERVYSSSGRTRSSGYGLEKSSGRDAGGRSKSFEREGVERSQKGSSKPSSLGMSQSRGRAPVRTQPSEEESPISPLGKSVGGSRSMGGPGPQSAGDPCSQFCSSHSLPDVQEHIKDVPRNHSYKHEEGYGMDDSHCVLLAFSCLIAWLQPGLRSRLRSERLTVVCFWFLKPIIWVRRRQTGLISPGKRGQRE", "length": 1270, "header": "tr|A0A8V1AFY5-1|A0A8V1AFY5_CHICK Computationally mapped isoform of Bassoon presynaptic cytomatrix protein OS=Gallus gallus OX=9031 GN=BSN PE=4 SV=1 CANONICAL=A0A8V1AFZ0-1" }, "locus": { "chromosome": "12", "start_pos": 2666890, "end_pos": 2661631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066210.1", "url": "https://www.ensembl.org/id/ENSGALT00010066210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040476.1", "url": "https://www.ensembl.org/id/ENSGALP00010040476.1" } ] } }, { "isoform_ac": "A0A8V1AFZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0/entry#A0A8V1AFZ0-1", "sequence": { "sequence": "MTESQRGCDGRDLPAPPVPWAGCPPAQVPPWPGAPPNPSLPLCLLMLDHAAGQRSAAPSLAQGSESPREMRGRGQAEGPRRTLQVDPHGQRAGRSPSASPERGSTPTSPYSLPQIAPLPSSTLCPICKTTELTSAPSQPNFNACTQCHSKVCNQCGFNPNPHLTEVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPSPSPSHSPAKLPAGQEKTPAPTQPSARPGTAATAVPPPEPPRAQSAALQREQHGQPKAAAPPEAARASLQHQQAKPSSSEQRKALGDPKPAALAPGAGAAEQPQEGLTGKLFGFGASLLTQASTLMSVQPEAPAPSPQASGKVPPKIVFSDASKEAGPKAGGAQGWVGAAKASKAEPGVKPKEVPKARVLCPLCKAEINVGSAEPPNYNACTSCRQQVCNMCGFNPAPHLVEKNEWLCLNCQTQRLLEGSLADPAPMPLPAPKQPTSGSPRHQPTAATQRAAAPAEPAAPPKQQPSPARSLWAPEQSRAPSPAPEKKPPVPAEEKPLPKAAPEPSVPVPKGKSVSPKPEGESKEGRAAPEAQRAKELEDAGKPYPPDLSRSPQSLSDTGYSSDGISSSQSEITGLVQQEEEKLSGTGLAGQSPPSPSELTKLESSMRPLLEVRGRSSGNGSGPRYLSITPEAFDSDEELEDILEEDEDSLEWENQREQRESVESSDEFGSKLRHDYVEDSSEGGFSPVPGRPKGREEVADEEFMRRQILEMSAEEDNLEEEEEEGYGRSKYSVQKAEAEKGKEPSPAKRRLPHGPGGLYKEERKELEAAESEDMSTTQGGLRRFKTIELNSTTGYGREMEVSQEADAGLEREPELEMESLTGSPEERSRGEYSSTLPATTPSYTSGTSPTSISSLEEDSDSSPSRRQRLEEVKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIDSEAESFDAVTSKLYKSGSEYNLPTFMSLYSPTEKVESVQPASKPLKSAEEAYEEMMRKAEMMQKQQVQQAQQDVSYGSTYQQVGYRSTEGQNGFQYQYADEYGYDSGPTRSSQPDYSSSLSKPGAVYEEILQTSQSIARMHQSSSFDLALEKGDKKKGQEEPYQEKHFLNAESAYAELMKQNGGPLTPGTSPTQLSAPVSFSTSEGSKVVPDVRVTQHFAKEGQDLAKLQSTPSAPSPTSKPITAPYTYSKGTSAVTTAAASPASTPRIYSSAEAASTPARSYSPAKSTISYGSQTEDITRSKVGVETSVQTAREKLQAVSDGKPPPAKTYSFFKSSSPPLSPTSPTQSPTHAAPRAAAPSGPTAKSTAEFSTQTQSPLLAYDVPTTTGPSASSPMVAQGTQTPHRAGSPRLTRQQSSQDAPFMLITLAADAASQTKPPSSSASPVSSPTRISRQVIAHGYGQEPEQPLATFIRAQHVKDPAQKVPVTSGPDGITGLYSWGALPAENISLCRISSIPGTSRVEPGPKVPSSSAVDLRTALKSAPIIITDQGMDLTSLATEARKYCLTLDQIPSRQSTAIQPLIINLNAQEQPHAIIAASSTTSLAIASPMLISQPKQPVVYGDPFQSRMDFGQGAGSPVCLAQVKQVEQGVQTGAGRASGTAVPAPTSKPEPPAPPQAKFSRYSLPSQMVKKDVLITQTSVAHSVSGLQQPFQQEQGSELYRAVPVELKTQSPLLALGGKKSQVMMVQVEDVAAGPVTKVLKEEPPANVLDLTGVKAESQVACCDVVYKFPFGSSCTGAFNPTSKVPEKKAADTVPSRKASGPLYGSREPEMPETFPYREQPAPALYEENKFYPTGAFGRLYSSMSDTNLSEIGMNYYPPKGDQPFHEAAVDLSTMKHSYSIGFAEGGYLGQGLQYGSFSDLRQPADLLGHPLPMRRYSSASNIYSDYRYSPRGDLASFQESSLAHYSATTAREISRMCAALNSMDHQYGARHANGPDTMSYGPGGGGLPAQPGGAAAPKPSGMFNPSVPETRQGFSGLAQYNVPGVRLGAVRQMFPSSATVRAADGMIYSTINTPIASTLPITTQPASVLRPMLRGLYRPYGPPGMAAVPLASLARVPVVAPRVPLAPQGLYRYPAPSRLPASSLMETPVYLGKAVSAAPGTGPAAKAPAAPATGVQRAEVSGAAPRTEPPAAGSKEGGQAAPAPKLASESVQREEREREEERQRKQQEHVLQLERERVELEKLRQLRLQEELERERAELQRHREKEQLLVQRELQELQCIKQQVLQQQQEERHAQLALQREQLAQQRLQLEHIHQLQHQLQQQLEEQKRQKTIFPAAGAEPTSRPSEGPAEVPRGPMHNGHGWTPAGQVLPGGPEGAGGPRYPAPQRPLSSSASDMSLQAEESWEPGRGIKKRNSMPRLRDAYEKETVRKTADSSVQTDEEDGEERYMLSRRRRSRRSTDCSVQTDEEDSGEWEQPVRRRRSRPSRHADASTEGKADGTARGVASVGIQTISDCSVQTEPDQLLRVSPSIHITTHDPRVEIIKYISAPEKTQRGESLACQTEPEPPPQPGIVVPQLTVPTTITPYSTNMQMVSTGPLDPHAVRQQTLGKFEKKKPDPLEIGYQSHLPADSLSQLVTRQPPRSPQVLYSPVSPLSPHRLLESSFATSERLNKAHVPPQKHFTDSAQRQQTLPRPIKTMQRSLSDPKPISPTSEEASKDRFSLYQHPLLPGTQVRAPLARKVKRTLPSPPPEEPHVALGSPATQQLYLGSLAPKAPAAAPVTKASLLKELDRDLKLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLLKDRGTRDHPYLRGLADRRDYLSDSELHSLRLATYDSTGLRPAPTAQYPDFTAASYGAYPYAAPPGPPAFPATRPQPPQFPTASTTQDGLPPAPLPAFASPATFPAPGTAYPELSAPAQPGFRPQNPYQAQGTFAGTASVPAAQPALYQSPSDAHQKPRQTSLAELEQKIPTNYEVISAATSSSAVPDVTLGAAAVSSSYEQYKAPEARLADRTGVTQGPSASFSSESLYTSLEQNIPRNYVMIEDISELTKESPAVDGQKVEPVGTGANGRHGKEKSELLDAEGPSRPCCYSKAEEESEEDIYDHHGPDHRGKNSYHRESNGRVSGSSAGSSYYYGDSEYRHSSRADKHGSGMALPKHSSKNLAPAVVSSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYAVTTSVSSSNVASRAKKLQDEITYGLKKNVYEQQKYYGVSSRDLVDEEERVYSSSGRTRSSGYGLEKSSGRDAGGRSKSFEREGVERSQKGSSKPSSLGMSQSRGRAPVRTQPSEEESPISPLGKSVGGSRSMGGPGPQSAGDPCSQFCSSHSLPDVQEHIKDVPRNHSYKHEEGYGMDDSHCVVSDSEAYHLGQEETDWFDKPREARSERVRHYGGHSSSQKRPPAKHTYHDYDEPPDEDPWQHDDYPQHREHRHHGDYGRHAASSRHDEQPRRSAKQHPRESGRHEPRGHTTPAAAKKAQQPEPRASAPYGPGASEYAPPSRHHGAEPQKVPKTPQPHGAPSPAQKPEPSAPAQQAAGRQPQAGQQAARQQPAARQGAQPAGTAQPRAQGPAAARPAQQQPGTGQPTGKAAATLHAQPGGHPAPQVSPGLLRPLAAAGEGLGTGACAAPGAHGRGHPYAPDSFGVWSLAPAVLGGCPPTGQPGAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFTSFW", "length": 3775, "header": "tr|A0A8V1AFZ0-1|A0A8V1AFZ0_CHICK Isoform 1 of Bassoon presynaptic cytomatrix protein OS=Gallus gallus OX=9031 GN=BSN PE=4 SV=1 CANONICAL=A0A8V1AFZ0-1" }, "locus": { "chromosome": "12", "start_pos": 2706080, "end_pos": 2660154, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066215.1", "url": "https://www.ensembl.org/id/ENSGALT00010066215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040481.1", "url": "https://www.ensembl.org/id/ENSGALP00010040481.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2725, "start_aa": "Thr", "end_pos": 2725, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2725", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "cochlear hair cell ribbon synapse", "id": "GO:0098683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "neuron projection terminus", "id": "GO:0044306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "cytoskeleton of presynaptic active zone", "id": "GO:0048788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048788", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "organelle", "id": "GO:0043226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "synaptic vesicle clustering", "id": "GO:0097091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "protein localization to synapse", "id": "GO:0035418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "presynaptic active zone assembly", "id": "GO:1904071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904071", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle cycle", "id": "GO:0098693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of presynaptic active zone", "id": "GO:0098882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1520, "end_pos": 1522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1882, "end_pos": 1884, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3420, "end_pos": 3422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" }, { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AFZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ0" }, { "id": "PF05715", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05715" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Zinc finger piccolo-type", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 180, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 221, 2725 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1520, "end_pos": 1522 }, { 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"recommended", "evidence": [ { "id": "A0A8V1AFY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 71", "type": "synonym", "evidence": [ { "id": "A0A8V1AFY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7", "locus": { "chromosome": "25", "start_pos": 1101173, "end_pos": 1097218, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027813", "url": "https://www.ensembl.org/id/ENSGALG00010027813" } ] } } ], "crossref": [ { "id": "A0A8V1AFY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857743", "url": "https://www.ncbi.nlm.nih.gov/gene/100857743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5P3", "url": "https://www.orthodb.org/?gene=A0A8V1A5P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAK1", "url": "https://www.orthodb.org/?gene=A0A8V1AAK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAK6", "url": "https://www.orthodb.org/?gene=A0A8V1AAK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADD7", "url": "https://www.orthodb.org/?gene=A0A8V1ADD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFY7", "url": "https://www.orthodb.org/?gene=A0A8V1AFY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHU3", "url": "https://www.orthodb.org/?gene=A0A8V1AHU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46984:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46984:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKELRAEQAAGKAWIGEMGGGGAEGIPPHSPPSFSEQYQCCGLLQQDLTELCARAGIISIPRVTVRPFPAGRFGSSATASPAAEGAEPHRLGEHCIQVELQNDDPRSVCGVFLRGGETEMLGVLSKCLPALGNLKTLNLWSTGLTDCMLPALGTMVASCSQSLTLEGNPLPENSFHVLMGASSTLSHLSLRNNCIDDTAAQLLGQGLSTMSSSNHSLLSLVLSFNCISDVGAGHIAEGLRWNRSLLSLSLAHNRIGDIGAQKLAEVLQPFKLRHEEVVERRRLLMEAQGQPRAVSIGRGVGAFDAAVRLSPAKQSKSTTKKKVRRWAANKGRARSVSEGAGGAPWGLLLTQLLPLCFSCSDGPLRSPTRPQPWYKGCQRGEAEHSSERHSGTLMGGHLLLWPPHPQDPSHCAQALHPAEPTHPLLEPGLHRDGHVILPGNRVLLNLNLAHNRITERGLGALLAAVEGQQQQEGAGGQQGLRRLSLHVSAGVGPVWDPLLPWDLPRGPNSSSPPTLLSIAAIALGPP", "length": 527, "header": "tr|A0A8V1AFY7-1|A0A8V1AFY7_CHICK Isoform 1 of Leucine rich repeat containing 71 OS=Gallus gallus OX=9031 GN=LRRC71 PE=4 SV=1 CANONICAL=A0A8V1AFY7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7/entry#A0A8V1A5P3-1", "sequence": { "sequence": "MEKELRAEQAAEQYQCCGLLQQDLTELCARAGIISIPRVTVRPFPAAGWKVEEEMLGVLSKCLPALGNLKTLNLWSTGLTDCMLPALGTMVASCSQLWSLTLEGNPLPENSFHVLMGASSTLSHLSLRNNCIDDTAAQLLGQGLSTMSSSNHSLLSLVLSFNCISDVGAGHIAEGLRWNRSLLSLSLAHNRIGDIGAQKLAEVLQPFKLRHEEVVERRRLLMEAQGQPRAAAPSGGYAPSLRGSDAAVRLSPAKQSKSTTKKKERLRKEDVKQSKKLTAPSDPRPGRSRGTKGVSEEKQSTQALHPAEPTHPLLEPGLHRDGHVILPGNRVLLNLNLAHNRITERGLGALLAAVEGQQQQEGAGGQQGLRRLSLHRNSFPTACAAFTRLQELLQQRDPLPQPAEDEEEHSLEP", "length": 413, "header": "tr|A0A8V1A5P3-1|A0A8V1A5P3_CHICK Computationally mapped isoform of Leucine rich repeat containing 71 OS=Gallus gallus OX=9031 GN=LRRC71 PE=1 SV=1 CANONICAL=A0A8V1AFY7-1" }, "locus": { "chromosome": "25", "start_pos": 1100010, "end_pos": 1097461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067397.1", "url": "https://www.ensembl.org/id/ENSGALT00010067397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041219.1", "url": "https://www.ensembl.org/id/ENSGALP00010041219.1" } ] } }, { "isoform_ac": "A0A8V1AAK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7/entry#A0A8V1AAK1-1", "sequence": { "sequence": "MEKELRAEQAAGKAWIGEMGGGGAEGIPPHSPPSFSEQYQCCGLLQQDLTELCARAGIISIPRVTVRPFPAGRFGSSATASPAAEGAEPHRLGEHCIQVELQNDDPRSVCGVFLRGWKVEEEMLGVLSKCLPALGNLKTLNLWSTGLTDCMLPALGTMVASCSQSLTLEGNPLPENSFHVLMGASSTLSHLSLRNNCIDDTAAQLLGQGLSTMSSSNHSLLSLVLSFNCISDVGAGHIAEGLRWNRSLLSLSLAHNRIGDIGAQKLAEVLQPFKLRHEEVVERRRLLMEAQGQHCIRPSPPTHCWSQACTAMAMSSCLGTGCCSTSTWPVSAGLGGPGCSMAPSPWPCSPYPLLQTTASRSGAWARCWPRWRGSSSRREPGGSRGCAASRCM", "length": 392, "header": "tr|A0A8V1AAK1-1|A0A8V1AAK1_CHICK Computationally mapped isoform of Leucine rich repeat containing 71 OS=Gallus gallus OX=9031 GN=LRRC71 PE=4 SV=1 CANONICAL=A0A8V1AFY7-1" }, "locus": { "chromosome": "25", "start_pos": 1099829, "end_pos": 1097461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067390.1", "url": "https://www.ensembl.org/id/ENSGALT00010067390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041216.1", "url": "https://www.ensembl.org/id/ENSGALP00010041216.1" } ] } }, { "isoform_ac": "A0A8V1AAK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7/entry#A0A8V1AAK6-1", "sequence": { "sequence": "MEKELRAEQAAEQYQCCGLLQQDLTELCARAGIISIPRVTVRPFPAAAEGAEPHRLGEHCIQVELQNDDPRSVCGVFLRGWKVEEEMLGVLSKCLPALGNLKTLNLWSTGLTDCMLPALGTMVASCSQLWSLTLEGNPLPENSFHVLMGASSTLSHLSLRNNCIDDTAAQLLGQGLSTMSSSNHSLLSLVLSFNCISDVGAGHIAEGLRWNRSLLSLSLAHNRIGDIGAQKLAEVLQPFKLRHEEVVERRRLLMEAQGQPRAAAPSGGYAPSLRGSDAAVRLSPAKQSKSTTKKKERLRKEDVKQSKKLTAPSDPRPGRSRGTKGVSEEKQSTQALHPAEPTHPLLEPGLHRDGHVILPGNRVLLNLNLAQEQFPHCLCGLHSAPGAAAAAGPPPPACGG", "length": 400, "header": "tr|A0A8V1AAK6-1|A0A8V1AAK6_CHICK Computationally mapped isoform of Leucine rich repeat containing 71 OS=Gallus gallus OX=9031 GN=LRRC71 PE=1 SV=1 CANONICAL=A0A8V1AFY7-1" }, "locus": { "chromosome": "25", "start_pos": 1099985, "end_pos": 1097461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067402.1", "url": "https://www.ensembl.org/id/ENSGALT00010067402.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041221.1", "url": "https://www.ensembl.org/id/ENSGALP00010041221.1" } ] } }, { "isoform_ac": "A0A8V1ADD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7/entry#A0A8V1ADD7-1", "sequence": { "sequence": "MEKELRAEQAAGKAWIGEMGGGGAEGIPPHSPPSFSEQYQCCGLLQQDLTELCARAGIISIPRVTVRPFPGRFGSSATASPAAEGAEPHRLGEHCIQVELQNDDPRSVCGVFLRGGETEMLGVLSKCLPALGNLKTLNLWSTGLTDCMLPALGTMVASCSQSLTLEGNPLPENSFHVLMGASSTLSHLSLRNNCIDDTAAQLLGQGLSTMSSSNHSLLSLVLSFNCISDVGAGHIAEGLRWNRSLLSLSLAHNRIGDIGAQKLAEVLQPFKLRHEEVVERRRLLMEAQGQPRAAAPSGGYAPSLRGSDAAVRLSPAKQSKSTTKKKVRRWAANKGSLGSPAFVGVRGWAVLDERHSGTLMGGHLLLWPPHPQDPSHCAQALHPAEPTHPLLEPGLHRDGHVILPGNRVLLNLNLAHNRITERGLGALLAAVEGQQQQEGAGGQQGLRRLSLHPWGHRCALWG", "length": 462, "header": "tr|A0A8V1ADD7-1|A0A8V1ADD7_CHICK Computationally mapped isoform of Leucine rich repeat containing 71 OS=Gallus gallus OX=9031 GN=LRRC71 PE=1 SV=1 CANONICAL=A0A8V1AFY7-1" }, "locus": { "chromosome": "25", "start_pos": 1101170, "end_pos": 1097461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067407.1", "url": "https://www.ensembl.org/id/ENSGALT00010067407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041223.1", "url": "https://www.ensembl.org/id/ENSGALP00010041223.1" } ] } }, { "isoform_ac": "A0A8V1AFY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7/entry#A0A8V1AFY7-1", "sequence": { "sequence": "MEKELRAEQAAGKAWIGEMGGGGAEGIPPHSPPSFSEQYQCCGLLQQDLTELCARAGIISIPRVTVRPFPAGRFGSSATASPAAEGAEPHRLGEHCIQVELQNDDPRSVCGVFLRGGETEMLGVLSKCLPALGNLKTLNLWSTGLTDCMLPALGTMVASCSQSLTLEGNPLPENSFHVLMGASSTLSHLSLRNNCIDDTAAQLLGQGLSTMSSSNHSLLSLVLSFNCISDVGAGHIAEGLRWNRSLLSLSLAHNRIGDIGAQKLAEVLQPFKLRHEEVVERRRLLMEAQGQPRAVSIGRGVGAFDAAVRLSPAKQSKSTTKKKVRRWAANKGRARSVSEGAGGAPWGLLLTQLLPLCFSCSDGPLRSPTRPQPWYKGCQRGEAEHSSERHSGTLMGGHLLLWPPHPQDPSHCAQALHPAEPTHPLLEPGLHRDGHVILPGNRVLLNLNLAHNRITERGLGALLAAVEGQQQQEGAGGQQGLRRLSLHVSAGVGPVWDPLLPWDLPRGPNSSSPPTLLSIAAIALGPP", "length": 527, "header": "tr|A0A8V1AFY7-1|A0A8V1AFY7_CHICK Isoform 1 of Leucine rich repeat containing 71 OS=Gallus gallus OX=9031 GN=LRRC71 PE=4 SV=1 CANONICAL=A0A8V1AFY7-1" }, "locus": { "chromosome": "25", "start_pos": 1100795, "end_pos": 1097461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067404.1", "url": "https://www.ensembl.org/id/ENSGALT00010067404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041222.1", "url": "https://www.ensembl.org/id/ENSGALP00010041222.1" } ] } }, { "isoform_ac": "A0A8V1AHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY7/entry#A0A8V1AHU3-1", "sequence": { "sequence": "MEKELRAEQAAEQYQCCGLLQQDLTELCARAGIISIPRVTVRPFPAAAEGAEPHRLGEHCIQVELQNDDPRSVCGVFLRGWKVEEEMLGVLSKCLPALGNLKTLNLWSTGLTDCMLPALGTMVASCSQLWSLTLEGNPLPENSFHVLMGASSTLSHLSLRNNCIDDTAAQLLGQGLSTMSSSNHSLLSLVLSFNCISDVGAGHIAEGLRWNRSLLSLSLAHNRIGDIGAQKLAEVLQPFKLRHEEVVERRRLLMEAQGQPRAAAPSGGYAPSLRGSDAAVRLSPAKQSKSTTKKKERLRKEDVKQSKKLTAPSDPRPGRSRGTKGVSEEKQSTQALHPAEPTHPLLEPGLHRDGHVILPGNRVLLNLNLAHNRITERGLGALLAAVEGQQQQEGAGGQQGLRRLSLHEQFPHCLCGLHSAPGAAAAAGPPPPACGG", "length": 436, "header": "tr|A0A8V1AHU3-1|A0A8V1AHU3_CHICK Computationally mapped isoform of Leucine rich repeat containing 71 OS=Gallus gallus OX=9031 GN=LRRC71 PE=1 SV=1 CANONICAL=A0A8V1AFY7-1" }, "locus": { "chromosome": "25", "start_pos": 1099985, "end_pos": 1097461, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067400.1", "url": "https://www.ensembl.org/id/ENSGALT00010067400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041220.1", "url": "https://www.ensembl.org/id/ENSGALP00010041220.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 215, "end_pos": 217 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 509, "end_pos": 511 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AFZ7-1", "uniprot_ac": "A0A8V1AFZ7", "uniprot_id": "A0A8V1AFZ7_CHICK", "mass": { "chemical_mass": 124715.0, "monoisotopic_mass": 124715.0 }, "refseq": { "ac": "XP_015135172", "name": "microtubule organization protein AKNA isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135172" }, "gene_names": [ { "name": "AKNA", "type": "recommended", "evidence": [ { "id": "A0A8V1AFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ] }, { "name": "AKNA", "type": "synonym", "evidence": [ { "id": "XP_015135172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135172" } ] } ], "protein_names": [ { "name": "AT-hook transcription factor", "type": "synonym", "evidence": [ { "id": "A0A8V1AFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7/entry#names_and_taxonomy" } ] }, { "name": "microtubule organization protein AKNA isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135172" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135172.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135172" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKNA", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7", "locus": { "chromosome": "17", "start_pos": 3126655, "end_pos": 3138776, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028894", "url": "https://www.ensembl.org/id/ENSGALG00010028894" } ] } } ], "crossref": [ { "id": "A0A8V1AFZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AFZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "107052190", "url": "https://www.ncbi.nlm.nih.gov/gene/107052190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107052190", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHLAMTE", "url": "https://omabrowser.org/oma/group/PHLAMTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAM2", "url": "https://www.orthodb.org/?gene=A0A8V1AAM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFZ7", "url": "https://www.orthodb.org/?gene=A0A8V1AFZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK93", "url": "https://www.orthodb.org/?gene=A0A8V1AK93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM11", "url": "https://www.orthodb.org/?gene=A0A8V1AM11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21510:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21510:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015135172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSSPWLRWTQSELGSQEPKCWEEEEEEDDEEEDFERHMDENGVIGLGAAAAELSDPQDSGSEWGQEAAGSPIWGDGEDLDVGSPAEPCWYAQQDLTEEEEEEEEEQGSSEEDERPEGPWGTESDGDPHAETPLKAPGTTTDGGGTSGPSDSSPVPTTPPRQRRGWGRARDPNQSPQTPQQPKPSWLSPSPRRRTDTKKPKDPTDICPYGRGRLNHPLPDLSKVEARVKVGQSYRPPPSRALPARSRPHGGPLVPKSPAEIVREVLLSSGEGAPPRPSAPPGVPQELRSPRQATALVQQLQDDYHKLLTKYAEAENTIDQLRLGAKVNLYADPPCASRSAHAGTMSGGCRVMAFSIPRASAAAISTAPNPQLPVGGAPAPQPAEHGRASSQPCSPRSPLGGCPTCVGPCCCAGPRLTQTLAEQTRKFQAQVDSFEAWIRAGSSVPQEQLQWFQRLRDTQDALERAYLEAREEQSLGDTGNFDPERTVEGDIFCLGMRLEELKERLERAAPGSPAVTEGLPGTGETVGDSGAVGLPRPLRHKQLQAEEDFGDLLQQYQRLKSLPASLSLEQLSLTGSAALEEAGGTAAGDNGPGGVLSGAQSLEEGTDLETSPSPPPQRKAVPLPHAEPPHPQGTHGRLSPVTTSLPPTTSRLPLAFPEPLPSRAAPSRHSSGAGSTATQRRALKPCHQEQRMVSPETDSGFIGSESSRVSLLARTPERRPLGSGMRGVLEPPVPAPVHPQKKEAPLLPPRKALRGPYPTPGHGPPPGNSVPPSTPSPSSSPVRWAGSQGSELGPEGDGGHSDSEGGDRSCTSGHPPSGTPASPSPALVHCDLLGSRMERDRAIRALQDEVWRLRLRLEESLHRSHSYPEGRAPHTPKGRRQPAASRASFLQDSAPVGEHSPTARGRATAGGSRGRWASLPRDGTPPDLTSRSDRSPRARGDSRPGAAPSAHKRPRSPPGAASLRGQQAAERREPEPVGTAHGRADTASAGAQHRVAPPRGEPSAAPCPRCHPDRTAAGAPSVDATRPQHSSTPRSPERCPTCRAPRGDADRAAHAQRSTDGATPPEPRGRPQAVQPEQPAGCWYLAGGPPVAYLAPVPVVPYAPSLLYRPPAAPTSAPHHSRSPPLSDLEEDLDRSLSAAVAAARRARVTSRRLGRVLAAELGRARAVRGSCLF", "length": 1175, "header": "tr|A0A8V1AFZ7-1|A0A8V1AFZ7_CHICK Isoform 1 of AT-hook transcription factor OS=Gallus gallus OX=9031 GN=AKNA PE=4 SV=1 CANONICAL=A0A8V1AFZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7/entry#A0A8V1AAM2-1", "sequence": { "sequence": "MGSSSPWLRWTQSELGSQEPKCWEEEEEEDDEEEDFERHMDENGVIGLGAAAAELSDPQDSGSEWGQEAAGSPIWGDGEDLDVGSPAEPCWYAQQDLTEEEEEEEEEQGSSEEDERPEGPWGTESDGDPHAETPLKAPGTTTDGGGTSGPSDSSPVPTTPPRQRRGWGRARDPNQSPQTPQQPKPSWLSPSPRRRTDTKKPKDPTDICPYGRGRLNHPLPDLSKVEARVKVGQSYRPPPSRALPARSRPHGGPLVPKSPAEIVREVLLSSGEGAPPRPSAPPGVPQELRSPRQATALVQQLQDDYHKLLTKYAEAENTIDQLRLGAKVNLYADPPCASRSAHAGTMSGGCRVMAFSIPRASAAAISTAPNPQLPVGGAPAPQPAEHGRASSQPCSPRSPLGGCPTCVGPCCCAGPRLTQTLAEQTRKFQAQVDSFEAWIRAGSSVPQEQLQWFQRLRDTQDALERAYLEAREEQSLGDTGNFDPERTVEGDIFCLGMRLEELKERLERAAPGSPAVTEGLPGTGETVGDSGAVGLPRPLRHKQLQAEEDFGDLLQQYQRLKSLPASLSLEQLSLTGSAALEEAGGTAAGDNGPGGVLSGAQSLEEGTDLETSPSPPPQRKAVPLPHAEPPHPQGTHGRLSPVTTSLPPTTSRLPLAFPEPLPSRAAPSRHSSGAGSTATQRRALKPCHQEQRMVSPETDSGFIGSESSRVSLLARTPERRPLGSGMRGVLEPPVPAPVHPQKKEAPLLPPRKALRGPYPTPGHGPPPGNSVPPSTPSPSSSPVRWAGSQGSELGPEGDGGHSDSEGGDRSCTSGHPPSGTPASPSPALVHCDLLGSRMERDRAIRALQDEVWRLRLRLEESLHRSHSYPEGRAPHTPKGRRQPAASRASFLQDSAPVGEHSPTARGRATAGGSRGRWASLPRDGTPPDLSAPSVDATRPQHSST", "length": 944, "header": "tr|A0A8V1AAM2-1|A0A8V1AAM2_CHICK Computationally mapped isoform of AT-hook transcription factor OS=Gallus gallus OX=9031 GN=AKNA PE=4 SV=1 CANONICAL=A0A8V1AFZ7-1" }, "locus": { "chromosome": "17", "start_pos": 3135415, "end_pos": 3129537, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069903.1", "url": "https://www.ensembl.org/id/ENSGALT00010069903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043029.1", "url": "https://www.ensembl.org/id/ENSGALP00010043029.1" } ] } }, { "isoform_ac": "A0A8V1AFZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7/entry#A0A8V1AFZ7-1", "sequence": { "sequence": "MGSSSPWLRWTQSELGSQEPKCWEEEEEEDDEEEDFERHMDENGVIGLGAAAAELSDPQDSGSEWGQEAAGSPIWGDGEDLDVGSPAEPCWYAQQDLTEEEEEEEEEQGSSEEDERPEGPWGTESDGDPHAETPLKAPGTTTDGGGTSGPSDSSPVPTTPPRQRRGWGRARDPNQSPQTPQQPKPSWLSPSPRRRTDTKKPKDPTDICPYGRGRLNHPLPDLSKVEARVKVGQSYRPPPSRALPARSRPHGGPLVPKSPAEIVREVLLSSGEGAPPRPSAPPGVPQELRSPRQATALVQQLQDDYHKLLTKYAEAENTIDQLRLGAKVNLYADPPCASRSAHAGTMSGGCRVMAFSIPRASAAAISTAPNPQLPVGGAPAPQPAEHGRASSQPCSPRSPLGGCPTCVGPCCCAGPRLTQTLAEQTRKFQAQVDSFEAWIRAGSSVPQEQLQWFQRLRDTQDALERAYLEAREEQSLGDTGNFDPERTVEGDIFCLGMRLEELKERLERAAPGSPAVTEGLPGTGETVGDSGAVGLPRPLRHKQLQAEEDFGDLLQQYQRLKSLPASLSLEQLSLTGSAALEEAGGTAAGDNGPGGVLSGAQSLEEGTDLETSPSPPPQRKAVPLPHAEPPHPQGTHGRLSPVTTSLPPTTSRLPLAFPEPLPSRAAPSRHSSGAGSTATQRRALKPCHQEQRMVSPETDSGFIGSESSRVSLLARTPERRPLGSGMRGVLEPPVPAPVHPQKKEAPLLPPRKALRGPYPTPGHGPPPGNSVPPSTPSPSSSPVRWAGSQGSELGPEGDGGHSDSEGGDRSCTSGHPPSGTPASPSPALVHCDLLGSRMERDRAIRALQDEVWRLRLRLEESLHRSHSYPEGRAPHTPKGRRQPAASRASFLQDSAPVGEHSPTARGRATAGGSRGRWASLPRDGTPPDLTSRSDRSPRARGDSRPGAAPSAHKRPRSPPGAASLRGQQAAERREPEPVGTAHGRADTASAGAQHRVAPPRGEPSAAPCPRCHPDRTAAGAPSVDATRPQHSSTPRSPERCPTCRAPRGDADRAAHAQRSTDGATPPEPRGRPQAVQPEQPAGCWYLAGGPPVAYLAPVPVVPYAPSLLYRPPAAPTSAPHHSRSPPLSDLEEDLDRSLSAAVAAARRARVTSRRLGRVLAAELGRARAVRGSCLF", "length": 1175, "header": "tr|A0A8V1AFZ7-1|A0A8V1AFZ7_CHICK Isoform 1 of AT-hook transcription factor OS=Gallus gallus OX=9031 GN=AKNA PE=4 SV=1 CANONICAL=A0A8V1AFZ7-1" }, "locus": { "chromosome": "17", "start_pos": 3135415, "end_pos": 3128201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069905.1", "url": "https://www.ensembl.org/id/ENSGALT00010069905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043031.1", "url": "https://www.ensembl.org/id/ENSGALP00010043031.1" } ] } }, { "isoform_ac": "A0A8V1AK93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7/entry#A0A8V1AK93-1", "sequence": { "sequence": "MGSSSPWLRWTQSELGSQEPKCWEEEEEEDDEEEDFERHMDENGVIGLGAAAAELSDPQDSGSEWGQEAAGSPIWGDGEDLDVGSPAEPCWYAQQDLTEEEEEEEEEQGSSEEDERPEGPWGTESDGDPHAETPLKAPGTTTDGGGTSGPSDSSPVPTTPPRQRRGWGRARDPNQSPQTPQQPKPSWLSPSPRRRTDTKKPKDPTDICPYGRGRLNHPLPDLSKVEARVKVGQSYRPPPSRALPARSRPHGGPLVPKSPAEIVREVLLSSGEGAPPRPSAPPGVPQELRSPRQATALVQQLQDDYHKLLTKYAEAENTIDQLRLGAKVNLYADPPCASRSAHAGTMSGGCRVMAFSIPRASAAAISTAPNPQLPVGGAPAPQPAEHGRASSQPCSPRSPLGGCPTCVGPCCCAGPRLTQTLAEQTRKFQAQVDSFEAWIRAGSSVPQEQLQWFQRLRDTQDALERAYLEAREEQSLGDTGNFDPERTVEGDIFCLGMRLEELKERLERAAPGSPAVTEGLPGTGETVGDSGAVGLPRPLRHKQLQAEEDFGDLLQQYQRLKSLPASLSLEQLSLTGSAALEEAGGTAAGDNGPGGVLSGAQSLEEGTDLETSPSPPPQRKAVPLPHAEPPHPQGTHGRLSPVTTSLPPTTSRLPLAFPEPLPSRAAPSRHSSGAGSTATQRRALKPCHQEQRMVSPETDSGFIGSESSRVSLLARTPERRPLGSGMRGVLEPPVPAPVHPQKKEAPLLPPRKALRGPYPTPGHGPPPGNSVPPSTPSPSSSPVRWAGSQGSELGPEGDGGHSDSEGGDRSCTSGHPPSGTPASPSPALVHCDLLGSRMERDRAIRALQDEVWRLRLRLEESLHRSHSYPEGRAPHTPKGRRQPAASRASFLQDSAPVGEHSPTARGRATAGGSRGRWASLPRDGTPPDLTQRSTDGATPPEPRGRPQAVQPEQPAGCWYLAGGPPVAYLAPVPVVPYAPSLLYRPPAAPTSAPHHSRSPPLSDLEEDLDRSLSAAVAAARRARVTSRRLGRVLAAELGRARAVRGSCLF", "length": 1049, "header": "tr|A0A8V1AK93-1|A0A8V1AK93_CHICK Computationally mapped isoform of AT-hook transcription factor OS=Gallus gallus OX=9031 GN=AKNA PE=4 SV=1 CANONICAL=A0A8V1AFZ7-1" }, "locus": { "chromosome": "17", "start_pos": 3135415, "end_pos": 3128201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069906.1", "url": "https://www.ensembl.org/id/ENSGALT00010069906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043032.1", "url": "https://www.ensembl.org/id/ENSGALP00010043032.1" } ] } }, { "isoform_ac": "A0A8V1AM11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7/entry#A0A8V1AM11-1", "sequence": { "sequence": "MGSSSPWLRWTQSELGSQEPKCWEEEEEEDDEEEDFERHMDENGVIGLGAAAAELSDPQDSGSEWGQEAAGSPIWGDGEDLDVGSPAEPCWYAQQDLTEEEEEEEEEQGSSEEDERPEGPWGTESDGDPHAETPLKAPGTTTDGGGTSGPSDSSPVPTTPPRQRRGWGRARDPNQSPQTPQQPKPSWLSPSPRRRTDTKKPKDPTDICPYGRGRLNHPLPDLSKVEARVKVGQSYRPPPSRALPARSRPHGGPLVPKSPAEIVREVLLSSGEGAPPRPSAPPGVPQELRSPRQATALVQQLQVNLYADPPCASRSAHAGTMSGGCRVMAFSIPRASAAAISTAPNPQLPVGGAPAPQPAEHGRASSQPCSPRSPLGGCPTCVGPCCCAGPRLTQTLAEQTRKFQAQVDSFEAWIRAGSSVPQEQLQWFQRLRDTQDALERAYLEAREEQSLGDTGNFDPERTVEGDIFCLGMRLEELKERLERAAPGSPAVTEGLPGTGETVGDSGAVGLPRPLRHKQLQAEEDFGDLLQQYQRLKSLPASLSLEQLSLTGSAALEEAGGTAAGDNGPGGVLSGAQSLEEGTDLETSPSPPPQRKAVPLPHAEPPHPQGTHGRLSPVTTSLPPTTSRLPLAFPEPLPSRAAPSRHSSGAGSTATQRRALKPCHQEQRMVSPETDSGFIGSESSRVSLLARTPERRPLGSGMRGVLEPPVPAPVHPQKKEAPLLPPRKALRGPYPTPGHGPPPGNSVPPSTPSPSSSPVRWAGSQGSELGPEGDGGHSDSEGGDRSCTSGHPPSGTPASPSPALVHCDLLGSRMERDRAIRALQDEVWRLRLRLEESLHRSHSYPEGRAPHTPKGRRQPAASRASFLQDSAPVGEHSPTARGRATAGGSRGRWASLPRDGTPPDLTSRSDRSPRARGDSRPGAAPSAHKRPRSPPGAASLRGQQAAERREPEPVGTAHGRADTASAGAQHRVAPPRGEPSAAPCPRCHPDRTAAGAPSVDATRPQHSSTPRSPERCPTCRAPRGDADRAAHAQRSTDGATPPEPRGRPQAVQPEQPAGCWYLAGGPPVAYLAPVPVVPYAPSLLYRPPAAPTSAPHHSRSPPLSDLEEDLDRSLSAAVAAARRARVTSRRLGRVLAAELGRARAVRGSCLF", "length": 1150, "header": "tr|A0A8V1AM11-1|A0A8V1AM11_CHICK Computationally mapped isoform of AT-hook transcription factor OS=Gallus gallus OX=9031 GN=AKNA PE=4 SV=1 CANONICAL=A0A8V1AFZ7-1" }, "locus": { "chromosome": "17", "start_pos": 3135415, "end_pos": 3128201, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069904.1", "url": "https://www.ensembl.org/id/ENSGALT00010069904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043030.1", "url": "https://www.ensembl.org/id/ENSGALP00010043030.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1116, "start_aa": "Thr", "end_pos": 1116, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1116", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 760, "start_aa": "Thr", "end_pos": 760, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr760", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 775, "start_aa": "Thr", "end_pos": 775, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr775", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 820, "start_aa": "Thr", "end_pos": 820, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr820", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107052190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052190", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZLV5-1", "protein_name": "AT-hook transcription factor", "gene_name": "Akna", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSGTKAQWAGSNLGQGPRRRRWAWAEEQDADGRGDQGWRNKQSLPEAITPELLEDFRQAQEHLPPLEWDPDMQGSEESSAEDTEADDVSSPEGSPVPLPWLSRHSQRLGLSDEELDETPGSPEVDLAGESSTELECEDQGDLSPPVAGQEPARGWVASIKQGSNYRPSEHPEAQPSVEHSRTKSWSNATMGLGQPSDSLGSTWEGDTDVPQPDTLPEALPQSPCHNLLHPDDRNEGDVAPATPTEFRHSLAAPARNPERSAGTWGRETTSLPSSRPEDQSWKRTKASPKPLPSRFTGSVSPLSTRLGAVNKVVSQHKQGATVAGHSSSRVPKYGRGRLNYPLPDFSKVGPRVRFPKDENYRPPKSRGHNRQQGSTRPLIFKSPAEIVRDVLLSSGDTPLAKESSLAHPVTRVPQEFQTPEQATELVHQLQEDYHKLLTKYAEAENTIDQLRLGAKVHLYSDPPQPSQSFCSGSMPQGSKVLSFSIPQPRSAEWWPDPAQDSQASEATGWPFPRTDLSPSSSPSMATPGRPHQSQGIAVDQPSTGQIQALTSQASRLLAKVESFEELVLAGHLPPQDQIKSLEQLRAAHMALEAEYVQACGEEHLDPQLDASQGSPRTLNLCRELEAEIYQLGQRLEELQDHIDQTRAEPEPCGTDLQDSTPTIPFQPQPAHLPMPSGPVPPPDVQTYQEPVTTTTSPGNSCMLPMPKEVNLGIRTEGSPRGLLVPLKDRKLQAEQDFHGLLERYLSVKSLPEALRVEDEEDPEEEEEQQDHPDTLKVDGSTAAPGKTEARRASPGQHPAQAEERHRAAIQEDKEQMVSMKSSNFQPSMARNRYTPVLDTAGVAQGGTKPMPSHQSSLTSLEESRPSDLLPRKALLRAGGPHTEEPWMVSPETDSGFVGSETSIVSPFTQTPEHQISHISTPGPSAQHLTVSAPGDGTSHPKVKGPVVPRRATEAGIPRSLTQRHHSSLSSLRRGAQSCHLEETPVAKIAVPRSEFKRQKQISKQHLPSGTTSPDSAPAPTAASMPHGSAESTANLLLTRTERDQAIKDLQAEVSRLRLQLEDSLHRPRPDSPACVAPAFNCSTQTQKKLVDSSPSWGSRYGSKSTERLFGEPSGAEPAEPMGRRQVRSSSVPRDVPRLSSSESESPAPRLSSEKNRTFEEHPQAAQWGTRPLGSTKRRERVSFWGQYTGQEYHILSPKTNLKDSGTASCPHCQPIRTQDTGNAVSREPLGSSAADTLRCSLCGGVKPSAEADGPSPAPSEKNTPQKPAPSTPSLKRKKRQTDSPVRMLPGLWYLAAAPPAPAPPALAYISAPIMPYPPPTVYYATPAPTSVHTASPQPAQGPRRTRHSVQLGLNDLEELQAALREAARAAENVRSTTRQLSHSLSADLRHARSLRGSCLF", "length": 1402 }, "evidence": [ { "id": "A0A8V1AFZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AFZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BDC4-1", "protein_name": "AT-hook transcription factor", "gene_name": "AKNA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSGTEVHWVEPGLGKGPQRRRWAWAEKGKDADESGTRSSEEEGPFPTASSPELLEDFRQAQQCLQPLKWGQDSQPAGCQDPESGESSEAESEEEDEDSPESSNLPLSWLPQQDPQSDMTKEDPSEALQGPEVQEAGESSPRLGYETYLSSGGHGSTSPTTLDWGQPAGWVASSKQASGDKLPEHSEVNPTADFSSPRSWSSGTVSLNHPSDNLDSTWEGETDVPQPTALAETSPQSPSHHLLNPNDRTEGSVALATPTEFQGSSAPLAQSLQCPADRWRAENSSLSCPQPGGQSWKQTRTSPKPLPSRFTGSISPPNPSPRPARQDRPPPRPGATLAGHSSSDAPKYGRGRLNYPLPDFSKVGPRVKFPKDESYHPPKARSHSRLPEGPAKPLIFKSPAEIVREVLLSSGDVCPGKNPPPTHPITRVPQEFQTPEQATKLVHQLQEDYHKLLTKYAEAENTIDQLRLGAKVNLYSDPPQPSHSIHTGTMPQGTKVLSFTIPQPHSVKWYVGPAEGPQASEASGSPSAGGDPRPSSPSSMPTPGWLQEDAGGIAQDQPSVEQAQELASQASRFLTKVESFIELIHAGWLTPQDQLKVFQQLKAAHAALEEDYLKACREWHLSQQLAGSKGTPRRFDPDREVEAEIFQLGIRLDELKDLMDHNEQEPGQVGSDLALDSPPATPSPHQPTDLPSPLEQTRTSAIQTLGPEPDATSTGPHLLPMNSDLSAPSNEAEDGPLGLPAPLRHKELRVEQDFHGLLERYLSVKSLPEALRMEEEEAEGQGRTLGFDRPDPAPGKAVAPRLPTRQPPAQAERSHGVPLEETMEQMAPVKPADVCASVTRDGHLQGLGKAEEVPPGHSRPPHPRGPKSATSHQSSLASLEGSGISERLPPKSLHQAGGPPLEEPWMASPETDSGFVGSETSRVSPLTQTPEHRLSQISTPGTLVRSFTLPVPQDAASHRQTKGLPVPRRTSEPSGPRSRAQRPPSGQDSPLQQRAPSFCLERALASEMAVPGSEFKGRKRIPEPILPSATISPPPTPAPVAATPPRGPAEITSTFFLTRTGRDQAIRELQDEVSRLRLRLEDSLHQHPQGRPTRSVSSCDRPTRARERSGDSSAAWSSHYVSKSMERSSGEPGGAEQAVPAGRRRARSSSVPREEPRLSLSSESEPASPRLFSERGRTTENSPQAARDGTKGVSSTGRPNRVTFRGQYTGQEYYVLTPKTVPRSSVPVSCPHCRPPRMEDPGDAVTRDPLGPSGSETLRCPLCSQVGSPSEGDGPDSATSAPEKAATSRNAPSTSSPKQRSKRAGSPPRPPPGLWYLAVAPSAPAPPAFAYISSVPVLPYPSATVYYAPPAPTSAPSVRAAAEWPPAACSRPARGSRHSVQLDLKDLEELNKALSRAVEAAESVRSTTQHMSRSLSAELRQARSLRGSCLF", "length": 1432 }, "evidence": [ { "id": "A0A8V1AFZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AFZ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z591-1", "protein_name": "Microtubule organization protein AKNA", "gene_name": "AKNA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSETEIRWAEPGLGKGPQRRRWAWAEDKRDVDRSSSQSWEEERLFPNATSPELLEDFRLAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSRLGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASGDKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPSHHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQTKTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPDFSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDTPPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPPQPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTSMPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQRLKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHIDQTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGPCPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEEEEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSMKPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLPQKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAASVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMAVPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICELQEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLPGEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDGKRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDPLGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPRPPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPPARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGSCLF", "length": 1439 }, "evidence": [ { "id": "A0A8V1AFZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AFZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80VW7-1", "protein_name": "Microtubule organization protein AKNA", "gene_name": "Akna", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSGAKAQWVGPSLGQGPRRRRWAWAEEQDTDGRRDQGWGNSQSLPEAPSPELLEDFRRAQEHLPPLEWDPDMQDSEESSGEETEADDASSPEGSTVPLPWLSRSNQQLDMSEEELDEASGRPEVDLAGESCTELECEDQGDSSPPPPGQGPAKGWVTFIKQGSNYRPSEHLEAQPSVEHSRTKSWSSGTVSLRQPSDSLGSTWEGDTEVPQPSILPKALPQSPCHNFPHPGDRNGGDVAPATPTEFRDSLAAPAQNAECSAGTWGEETTSLPSSRPEDQTWKRTKTSPKPLPSRFTGSVSPLSTRLGAIKKVVPQHKQGATLAGHSSSQAPKYGRGRRLNYPLPDFSKVGPRVRFPKDENYRPPKSRGHNRQQGSTRPLIFKSPAEIVRDVLLSSGEASLAKESSLAHTITRVPQEFQTPEQATELVHQLQEDYHKLLTKYAEAENTIDQLRLGAKVHLYSDPPQPSQSFCSGSMPQGSKVLSFSIPQPRVAEWWPDPAQDPQASEATGWPFPRTDLSPSSSPGVATPGRLPQSQGIATDQPSTGQTQALTSQASRLLAKVQSFEELVLAGHLPPQDQIKSLEQLRAAHMALEAEYLQACREELLDPQLDASQGSPRTLNLCRELEAEIYHLGQRLEELQDHMDQTQRETEPCRPDLQDSTPTMSFLPQSAHLSMPSGPVSLPDGQTYQEPATTTTTSPGSSCTLPINKKLSLSIKTEESPRGLPVPLRDRTLQVEQDFHGLLERYLSVKSLPEALRDEDEDDLEEEEEEQDHQGPLEVDSPATAPGKTEAVRVPPGERPTQAEESHRDATQEDEEQMGPMKSPDFRPSMARDTYTPVLDTAEVAQRGTKAMVSHQSSLTSLEESRPSELLPRKALLRAGGPHTEEPWMVSPETDSGFVGSETSIVSPFTQTPEHRLSHVSTSGPSAQHLTASVPGDRTSHPKARGLMVPRRATETGIPRSRTQQHFSSLSSPGRGAQSCHLEETSVAKIAVPRSEFKRQKQISKQLLPSGRTSPDSAPAPTAASTPHGSAESTANLLLNRTERDQAIKDLQAEVSRLRLQLEDSLHRPHPDGPACVASAFNHSTQTQEKLGSSPSWGPHYGSKSTERLSREPNGVEPAEPMGRRRARSSSVPRDVPRLYLSSESESPAPRLSSEKSRTFEEHPEAAQWGTRPQSSSKRRERVSFRGQYTGQEYHILSPKAILKDSGTPSCPHCHPIRTQDTGSAVSRDTTRGSSAADTLRCALCGEVKSSAEADGSSSGPSEKNTPKKPSTPILKRKNRQTGSPVRMAPGLWYLAAAPPAPAPPALAYISSAPIMPYLPPTVYYAAPAPTSAQTASPQPARGPRRTRHSVQLGLNDLEELQAALREAAQAAENVRSTTRQLSRSLSADLRHARSLRGSCLF", 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"fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "pmid": "" }, { "name": "epithelial to mesenchymal transition", "id": "GO:0001837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "pmid": "" }, { "name": "neuroblast division in subventricular zone", "id": "GO:0021849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021849", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "pmid": "" }, { "name": "neuroblast delamination", "id": "GO:0060234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AG07-1", "uniprot_ac": "A0A8V1AG07", "uniprot_id": "A0A8V1AG07_CHICK", "mass": { "chemical_mass": 63849.0, "monoisotopic_mass": 63849.0 }, "refseq": {}, "gene_names": [ { "name": "LOC428319", "type": "recommended", "evidence": [ { "id": "A0A8V1AG07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07" } ] } ], "protein_names": [ { "name": "BTB domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AG07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC428319", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07", "locus": {} } ], "crossref": [ { "id": "A0A8V1AG07", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AG07", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG07", "url": "https://www.orthodb.org/?gene=A0A8V1AG07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIA5", "url": "https://www.orthodb.org/?gene=A0A8V1AIA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AG07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEGCVRTELKLTARPSTAMGSAQEAEELDPQAEVVADTVLEVGGRLFQVSRRALSLHSRYFEAMFFGGTRESSEHHIVIRGTDAVPFQALLEFTRTAQVLIGQENVTSLLETADFFQFDRVKLLCEKFLERELHVSNCLGLMAYSQRFAFIELHASAMNVALTHWGDVVSQEEFKALPKETLMQFLRSDDLFVPREDVVFDSIMVWIMEDPATREKDFLDLVAEVRVAFLSLSFLDILVKRSKRPGQADTFCRLIRRLDSCPPPSWQNVALRPYTGRSYDTLYVLGGKRDKEQQELFLFQPKTGTWQACSPLQRRNLTQYAVAAVGSFLFVTGGYFRDEFVWYSVDWVLIYNCLSNSWLEGPAMKKSRNSHCAVGVGLYLYVLGGSTDEGIIAEVERMALVDSEWESMSPMVQPVERGDAVSVGTRIYVVCGLDENGHVYDGVQRLNTETDSWDVISFSPLPRYDLCITSLNGALYTIGGEAFRFDVETDEWTHVDEECLTQKFFMGCCTVNGQIYLLGQRKGNSALPIVVLFDPYVDMCQVIDNKLPCPLPIHGCVSVRRFDT", "length": 565, "header": "tr|A0A8V1AG07-1|A0A8V1AG07_CHICK Isoform 1 of BTB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC428319 PE=4 SV=1 CANONICAL=A0A8V1AG07-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AG07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07/entry#A0A8V1AG07-1", "sequence": { "sequence": "MSEGCVRTELKLTARPSTAMGSAQEAEELDPQAEVVADTVLEVGGRLFQVSRRALSLHSRYFEAMFFGGTRESSEHHIVIRGTDAVPFQALLEFTRTAQVLIGQENVTSLLETADFFQFDRVKLLCEKFLERELHVSNCLGLMAYSQRFAFIELHASAMNVALTHWGDVVSQEEFKALPKETLMQFLRSDDLFVPREDVVFDSIMVWIMEDPATREKDFLDLVAEVRVAFLSLSFLDILVKRSKRPGQADTFCRLIRRLDSCPPPSWQNVALRPYTGRSYDTLYVLGGKRDKEQQELFLFQPKTGTWQACSPLQRRNLTQYAVAAVGSFLFVTGGYFRDEFVWYSVDWVLIYNCLSNSWLEGPAMKKSRNSHCAVGVGLYLYVLGGSTDEGIIAEVERMALVDSEWESMSPMVQPVERGDAVSVGTRIYVVCGLDENGHVYDGVQRLNTETDSWDVISFSPLPRYDLCITSLNGALYTIGGEAFRFDVETDEWTHVDEECLTQKFFMGCCTVNGQIYLLGQRKGNSALPIVVLFDPYVDMCQVIDNKLPCPLPIHGCVSVRRFDT", "length": 565, "header": "tr|A0A8V1AG07-1|A0A8V1AG07_CHICK Isoform 1 of BTB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC428319 PE=4 SV=1 CANONICAL=A0A8V1AG07-1" }, "locus": { "chromosome": "28", "start_pos": 970336, "end_pos": 965435, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068624.1", "url": "https://www.ensembl.org/id/ENSGALT00010068624.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042191.1", "url": "https://www.ensembl.org/id/ENSGALP00010042191.1" } ] } }, { "isoform_ac": "A0A8V1AIA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07/entry#A0A8V1AIA5-1", "sequence": { "sequence": "MSEGCVRTELKLTARPSTAMGSAQEAEELDPQAEVVADTVLEVGGRLFQVSRRALSLHSRYFEAMFFGGTRESSEHHIVIRGTDAVPFQALLEFTRTAQVLIGQENVTSLLETADFFQFDRVKLLCEKFLERELHVSNCLGLMAYSQRFAFIELHASAMNVALTHWGDVVSQEEFKALPKETLMQFLRSDDLFVPREDVVFDSIMVWIMEDPATREKDFLDLVAEVRVAFLSLSFLDILVKRSKRPGQADTFCRLIRRLDSCPPPSWQNVALRPYTGRSYDTLYVLGGKRDKEQQELFLFQPKTGTWQACSPLQRRNLTQYAVAAVGSFLFVTGGYFRDEFVWYSVDWVLIYNCLSNSWLEGPAMKKSRNSHCAVGVGLYLYVLGGSTDEGIIAEVERMALVDSEWESMSPMVQPVERGDAVSVGTRIYVVCGLDENGHVYDGVQRLNTETDSWDVISFSPLPREN", "length": 466, "header": "tr|A0A8V1AIA5-1|A0A8V1AIA5_CHICK Computationally mapped isoform of BTB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC428319 PE=4 SV=1 CANONICAL=A0A8V1AG07-1" }, "locus": { "chromosome": "28", "start_pos": 970336, "end_pos": 967186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068623.1", "url": "https://www.ensembl.org/id/ENSGALT00010068623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042190.1", "url": "https://www.ensembl.org/id/ENSGALP00010042190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG07" } ], "pmid": "" } ] }, { "name": 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"https://www.ebi.ac.uk/interpro/entry/IPR044641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8B7", "url": "https://www.orthodb.org/?gene=A0A8V1A8B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG12", "url": "https://www.orthodb.org/?gene=A0A8V1AG12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK55", "url": "https://www.orthodb.org/?gene=A0A8V1AK55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10553", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10553", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10553:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10553:SF5", "database": "PANTHER", 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"Protein" ] } ], "sequence": { "sequence": "MANVGGGGGGAGKMADKEKKKKESILDLSKYIDKTIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRECLQLEVTHKDHQVQLLVPRSTTQNPNPVSESVVQRLLEQLGAVPTALGSCSMPTDPPLLFPQALLLSAEGGTAPLLSVRNCSYHEASPQPPLLWTE", "length": 166, "header": "tr|A0A8V1AG12-1|A0A8V1AG12_CHICK Isoform 1 of LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated OS=Gallus gallus OX=9031 GN=LSM7 PE=1 SV=1 CANONICAL=A0A8V1AG12-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG12/entry#A0A8V1A8B7-1", "sequence": { "sequence": "MANVGGGGGGAGKMADKEKKKKESILDLSKYIDKTIRVKFQGGREDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDG", "length": 92, "header": "tr|A0A8V1A8B7-1|A0A8V1A8B7_CHICK Computationally mapped isoform of LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated OS=Gallus gallus OX=9031 GN=LSM7 PE=1 SV=1 CANONICAL=A0A8V1AG12-1" }, "locus": { "chromosome": "28", "start_pos": 977805, "end_pos": 973399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068652.1", "url": "https://www.ensembl.org/id/ENSGALT00010068652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042197.1", "url": "https://www.ensembl.org/id/ENSGALP00010042197.1" } ] } }, { "isoform_ac": "A0A8V1AG12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG12/entry#A0A8V1AG12-1", "sequence": { "sequence": "MANVGGGGGGAGKMADKEKKKKESILDLSKYIDKTIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRECLQLEVTHKDHQVQLLVPRSTTQNPNPVSESVVQRLLEQLGAVPTALGSCSMPTDPPLLFPQALLLSAEGGTAPLLSVRNCSYHEASPQPPLLWTE", "length": 166, "header": "tr|A0A8V1AG12-1|A0A8V1AG12_CHICK Isoform 1 of LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated OS=Gallus gallus OX=9031 GN=LSM7 PE=1 SV=1 CANONICAL=A0A8V1AG12-1" }, "locus": { "chromosome": "28", "start_pos": 977805, "end_pos": 974655, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068649.1", "url": "https://www.ensembl.org/id/ENSGALT00010068649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042196.1", "url": "https://www.ensembl.org/id/ENSGALP00010042196.1" } ] } }, { "isoform_ac": "A0A8V1AK55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG12/entry#A0A8V1AK55-1", "sequence": { "sequence": "RKFRLGSPQGANGLRRRETSLLVADKEKKKKESILDLSKYIDKTIRVKFQGGREASGVLKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDG", "length": 125, "header": "tr|A0A8V1AK55-1|A0A8V1AK55_CHICK Computationally mapped isoform of U6 snRNA-associated Sm-like protein LSm7 OS=Gallus gallus OX=9031 GN=LSM7 PE=1 SV=1 CANONICAL=A0A8V1AG12-1" }, "locus": { "chromosome": "28", "start_pos": 977886, "end_pos": 973399, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068655.1", "url": "https://www.ensembl.org/id/ENSGALT00010068655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042198.1", "url": "https://www.ensembl.org/id/ENSGALP00010042198.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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Process", "total": 2, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG12" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG12" }, { "id": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AG21-1", "uniprot_ac": "A0A8V1AG21", "uniprot_id": "A0A8V1AG21_CHICK", "mass": { "chemical_mass": 192768.0, "monoisotopic_mass": 192768.0 }, "refseq": {}, "gene_names": [ { "name": "NES", "type": "recommended", "evidence": [ { "id": "A0A8V1AG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21" } ] } ], "protein_names": [ { "name": "Nestin", "type": "synonym", "evidence": [ { "id": "A0A8V1AG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NES", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21", "locus": { "chromosome": "25", "start_pos": 1017524, "end_pos": 1009686, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028348", "url": "https://www.ensembl.org/id/ENSGALG00010028348" } ] } } ], "crossref": [ { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG21", "url": "https://www.orthodb.org/?gene=A0A8V1AG21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIC1", "url": "https://www.orthodb.org/?gene=A0A8V1AIC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIC5", "url": "https://www.orthodb.org/?gene=A0A8V1AIC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK65", "url": "https://www.orthodb.org/?gene=A0A8V1AK65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47051:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47051:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AG21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSMEGFVGARALGEESLQMWDLNKRLEAYLARVKFLEEENEGLRAEIQSTKENPAGDPRRARYEEELRSLRDALHRAFTEKCAAELARDNLYEEVQHVRSRCQKEQAAREEAKRQLSSSKKELEEERRAQIWLKERAVQLEKEVEALLEVHEEEKAGLDQELASFSQSLEGFRCAPVAFQPVEVEDYSKRLSEIWRGAVETYKAEVSQLERALGQAKENLWQVAEDNQQSQLQLRHLEKELVGLKVRKEMLEESLGQQWQEQHGEAEKFQLAIEALEQEKQSLQVQIAQVLEDRQQLMHLKMSLSLEVATYRTLLEAESTRLQMPPGEFKLANSLRDVKLEASSSKHRASLAAFPRPEGVAQLCRTPGDALKVLTPKSKSSSALEFQKISSVLQAPRSWEPAAPSPTVPVLSPEPGSGGAESPVHECGAGKESPMLSPLSPEQLVSHALQDALKEMQDDAEAKEVPTLSATQSTRDGDLEATMEEEEAAGTQGVGAEGETVSPPGLCLCSNEPTLLSATQSDAESQEEMWEEERSKEEMLNPLSSMESQEPGGEPWGGDTRGSRLQVGKEDMEATSTEALHVSEKKEQREIWSPSREDEECEFPDEEREMQEEGSLQMEIEAACAVPVGSHPVLPTGIHLQEDFLEREQESEHQEMSLGELGAAAGEEREQEVCQELKASSIEEAMPAAEGSSGSGEDTTGRESTGRARDDEGEEEDKGREALGEDDPQAGEALGAKELGQETMGLEEAEGMWEESVDLQEEHRDLQEGHGDLQVEHEDLWEEHGHIQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHGDLQVEHEDLQVEHGDLQVEHEDLWEEHRDVQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHEDLQEEHGDTQEEHGDLQVEHGDLQEEHRDLQEGHGDLKEEHGDLQVEHEDLQVEHGDLQVEHGDLQEEHGDTQEEHGDTQEEHGDLQEEHGDLQEEHGDLQEEHGDLQVEHGDLQEEHGDTQEEHRDLQEVHGDQQEEHRDLQEEHGDLQKGHGDLQGEHGDLQVEHGDLQDEYGDTQEEHRDLQEVHGDQQEEHRNLQEGHGDLQEGHGDLWKEHGVLKEEHGDLQERHGDLQEESGDPQEEPGEPWVQHGEQGSAGDGLEQDMVLQPGEGAWGREDNDISQKQQAQDWEGTAEDEEETGVNTITSQEPTQVDDNPHAEAAENEERDVTSPTAMEETQEGEDEGDAGSEVQSQQQPQDTPGQEAELAPGQKEVRYGDTGEAPGDPQEPAEALEVEDEELSSEPIELERGSPDTAVMQQDLGNGAESDEPMEEDFQSEDAQLEEPKACRMELEDTLLNSTPLCAYSGEMLESDPNPPSSGGDGEAAPEMAQEEEGELRGSDEATVHAEPESCEELSPAPQCTEEEEGYFIVSAPSQEGSSMEEAENSEEFEEIKVEAAEDRKDELTAPGVASLVPEDEGHSEPFVGEAEDVKMPLGEFEMPKEEDEEDAGGFAAELEEGLTVPVAEGLSEGHTDNTTLGDEGLGEEDEQDGDNPPATETSNTDPSNTDPPPGTMLEHGAGMEAAEYLPDVPTQLPVDIMKDSDILEIVEQALEFNQELVLGAKLAKDGQEEDGDAQPPQEEEGGSSPTSSSDEQPTVQEAVAEPERTKNGEQNGLHRQASLEDLAEFTEEGLNGITHPGEAPAAHTLPLPSKHSGAEPVPELSPLQDHVLRPEQEPWSSGEE", "length": 1740, "header": "tr|A0A8V1AG21-1|A0A8V1AG21_CHICK Isoform 1 of Nestin OS=Gallus gallus OX=9031 GN=NES PE=1 SV=1 CANONICAL=A0A8V1AG21-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AG21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21/entry#A0A8V1AG21-1", "sequence": { "sequence": "MLSMEGFVGARALGEESLQMWDLNKRLEAYLARVKFLEEENEGLRAEIQSTKENPAGDPRRARYEEELRSLRDALHRAFTEKCAAELARDNLYEEVQHVRSRCQKEQAAREEAKRQLSSSKKELEEERRAQIWLKERAVQLEKEVEALLEVHEEEKAGLDQELASFSQSLEGFRCAPVAFQPVEVEDYSKRLSEIWRGAVETYKAEVSQLERALGQAKENLWQVAEDNQQSQLQLRHLEKELVGLKVRKEMLEESLGQQWQEQHGEAEKFQLAIEALEQEKQSLQVQIAQVLEDRQQLMHLKMSLSLEVATYRTLLEAESTRLQMPPGEFKLANSLRDVKLEASSSKHRASLAAFPRPEGVAQLCRTPGDALKVLTPKSKSSSALEFQKISSVLQAPRSWEPAAPSPTVPVLSPEPGSGGAESPVHECGAGKESPMLSPLSPEQLVSHALQDALKEMQDDAEAKEVPTLSATQSTRDGDLEATMEEEEAAGTQGVGAEGETVSPPGLCLCSNEPTLLSATQSDAESQEEMWEEERSKEEMLNPLSSMESQEPGGEPWGGDTRGSRLQVGKEDMEATSTEALHVSEKKEQREIWSPSREDEECEFPDEEREMQEEGSLQMEIEAACAVPVGSHPVLPTGIHLQEDFLEREQESEHQEMSLGELGAAAGEEREQEVCQELKASSIEEAMPAAEGSSGSGEDTTGRESTGRARDDEGEEEDKGREALGEDDPQAGEALGAKELGQETMGLEEAEGMWEESVDLQEEHRDLQEGHGDLQVEHEDLWEEHGHIQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHGDLQVEHEDLQVEHGDLQVEHEDLWEEHRDVQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHEDLQEEHGDTQEEHGDLQVEHGDLQEEHRDLQEGHGDLKEEHGDLQVEHEDLQVEHGDLQVEHGDLQEEHGDTQEEHGDTQEEHGDLQEEHGDLQEEHGDLQEEHGDLQVEHGDLQEEHGDTQEEHRDLQEVHGDQQEEHRDLQEEHGDLQKGHGDLQGEHGDLQVEHGDLQDEYGDTQEEHRDLQEVHGDQQEEHRNLQEGHGDLQEGHGDLWKEHGVLKEEHGDLQERHGDLQEESGDPQEEPGEPWVQHGEQGSAGDGLEQDMVLQPGEGAWGREDNDISQKQQAQDWEGTAEDEEETGVNTITSQEPTQVDDNPHAEAAENEERDVTSPTAMEETQEGEDEGDAGSEVQSQQQPQDTPGQEAELAPGQKEVRYGDTGEAPGDPQEPAEALEVEDEELSSEPIELERGSPDTAVMQQDLGNGAESDEPMEEDFQSEDAQLEEPKACRMELEDTLLNSTPLCAYSGEMLESDPNPPSSGGDGEAAPEMAQEEEGELRGSDEATVHAEPESCEELSPAPQCTEEEEGYFIVSAPSQEGSSMEEAENSEEFEEIKVEAAEDRKDELTAPGVASLVPEDEGHSEPFVGEAEDVKMPLGEFEMPKEEDEEDAGGFAAELEEGLTVPVAEGLSEGHTDNTTLGDEGLGEEDEQDGDNPPATETSNTDPSNTDPPPGTMLEHGAGMEAAEYLPDVPTQLPVDIMKDSDILEIVEQALEFNQELVLGAKLAKDGQEEDGDAQPPQEEEGGSSPTSSSDEQPTVQEAVAEPERTKNGEQNGLHRQASLEDLAEFTEEGLNGITHPGEAPAAHTLPLPSKHSGAEPVPELSPLQDHVLRPEQEPWSSGEE", "length": 1740, "header": "tr|A0A8V1AG21-1|A0A8V1AG21_CHICK Isoform 1 of Nestin OS=Gallus gallus OX=9031 GN=NES PE=1 SV=1 CANONICAL=A0A8V1AG21-1" }, "locus": { "chromosome": "25", "start_pos": 1016896, "end_pos": 1009717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068668.1", "url": "https://www.ensembl.org/id/ENSGALT00010068668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042206.1", "url": "https://www.ensembl.org/id/ENSGALP00010042206.1" } ] } }, { "isoform_ac": "A0A8V1AIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21/entry#A0A8V1AIC1-1", "sequence": { "sequence": "MLSMEGFVGARALGEESLQMWDLNKRLEAYLARVKFLEEENEGLRAEIQSTKENPAGDPRRARYEEELRSLRDALHRAFTEKCAAELARDNLYEEVQHVRSRCQKEQAAREEAKRQLSSSKKELEEERRAQIWLKERAVQLEKEVEALLEVHEEEKAGLDQELASFSQSLEGFRCAPVAFQPVEVEDYSKRLSEIWRGAVETYKAEVSQLERALGQAKENLWQVAEDNQQSQLQLRHLEKELVGLKVRKEMLEESLGQQWQEQHGEAEKFQLAIEALEQEKQSLQVQIAQVLEDRQQLMHLKMSLSLEVATYRTLLEAESTRLQMPPGEFKLANSLRDVKLEASSSKHRASLAAFPRPEGVAQLCRTPGDALKVLTPKSKSSSALEFQKISSVLQAPRSWEPAAPSPTVPVLSPEPGSGGAESPVHECGAGKESPMLSPLSPEQLVSHALQDALKEMQDDAEAKEVPTLSATQSTRDGDLEATMEEEEAAGTQGVGAEGETVSPPGLCLCSNEPTLLSATQSDAESQEEMWEEERSKEEMLNPLSSMESQEPGGEPWGGDTRGSRLQVGKEDMEATSTEALHVSEKKEQREIWSPSREDEECEFPDEEREMQEEGSLQMEIEAACAVPVGSHPVLPTGIHLQEDFLEREQESEHQEMSLGELGAAAGEEREQEVCQELKASSIEEAMPAAEGSSGSGEDTTGRESTGRARDDEGEEEDKGREALGEDDPQAGEALGAKELGQETMGLEEAEGMWEESVDLQEEHRDLQEGHGDLQVEHEDLWEEHGHIQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHEDLQEEHGDTQEEHGDLQEEHGDLQEEHGDLQEEHGDLQEEHGDLQVEHGDLQVEHGDLQEEHGDTQEEHRDLQEVHGDQQEEHRDLQEEHGDLQKGHGDLQGEHGDLQVEHGDLQDEYGDTQEEHRDLQEVHGDQQEEHRNLQEGHGDLQEGHGDLWKEHGVLKEEHGDLQERHGDLQEESGDPQEEPGEPWVQHGEQGSAGDGLEQDMVLQPGEGAWGREDNDISQKQQAQDWEGTAEDEEETGVNTITSQEPTQVDDNPHAEAAENEERDVTSPTAMEETQEGEDEGDAGSEVQSQQQPQDTPGQEAELAPGQKEVRYGDTGEAPGDPQEPAEALEVEDEELSSEPIELERGSPDTAVMQQDLGNGAESDEPMEEDFQSEDAQLEEPKACRMELEDTLLNSTPLCAYSGEMLESDPNPPSSGGDGEAAPEMAQEEEGELRGSDEATVHAEPESCEELSPAPQCTEEEEGYFIVSAPSQEGSSMEEAENSEEFEEIKVEAAEDRKDELTAPGVASLVPEDEGHSEPFVGEAEDVKMPLGEFEMPKEEDEEDAGGFAAELEEGLTVPVAEGLSEGHTDNTTLGDEGLGEEDEQDGDNPPATETSNTDPSNTDPPPGTMLEHGAGMEAAEYLPDVPTQLPVDIMKDSDILEIVEQALEFNQELVLGAKLAKDGQEEDGDAQPPQEEEGGSSPTSSSDEQPTVQEAVAEPERTKNGEQNGLHRQASLEDLAEFTEEGLNGITHPGEAPAAHTLPLPSKHSGAEPVPELSPLQDHVLRPEQEPWSSGEE", "length": 1614, "header": "tr|A0A8V1AIC1-1|A0A8V1AIC1_CHICK Computationally mapped isoform of Nestin OS=Gallus gallus OX=9031 GN=NES PE=1 SV=1 CANONICAL=A0A8V1AG21-1" }, "locus": { "chromosome": "25", "start_pos": 1016896, "end_pos": 1009717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068667.1", "url": "https://www.ensembl.org/id/ENSGALT00010068667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042205.1", "url": "https://www.ensembl.org/id/ENSGALP00010042205.1" } ] } }, { "isoform_ac": "A0A8V1AIC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21/entry#A0A8V1AIC5-1", "sequence": { "sequence": "MLSMEGFVGARALGEESLQMWDLNKRLEAYLARVKFLEEENEGLRAEIQSTKENPAGDPRRARYEEELRSLRDALHRAFTEKCAAELARDNLYEEVQHVRSRCQKEQAAREEAKRQLSSSKKELEEERRAQIWLKERAVQLEKEVEALLEVHEEEKAGLDQELASFSQSLEGFRCAPVAFQPVEVEDYSKRLSEIWRGAVETYKAEVSQLERALGQAKENLWQVAEDNQQSQLQLRHLEKELVGLKVRKEMLEESLGQQWQEQHGEAEKFQLAIEALEQEKQSLQVQIAQVLEDRQQLMHLKMSLSLEVATYRTLLEAESTRLQMPPGEFKLANSLRDVKLEASSSKHRASLAAFPRPEGVAQLCRTPGDALKVLTPKSKSSSALEFQKISSVLQAPRSWEPAAPSPTVPVLSPEPGSGGAESPVHECGAGKESPMLSPLSPEQLVSHALQDALKEMQDDAEAKEVPTLSATQSTRDGDLEATMEEEEAAGTQGVGAEGETVSPPGLCLCSNEPTLLSATQSDAESQEEMWEEERSKEEMLNPLSSMESQEPGGEPWGGDTRGSRLQVGKEDMEATSTEALHVSEKKEQREIWSPSREDEECEFPDEEREMQEEGSLQMEIEAACAVPVGSHPVLPTGIHLQEDFLEREQESEHQEMSLGELGAAAGEEREQEVCQELKASSIEEAMPAAEGSSGSGEDTTGRESTGRARDDEGEEEDKGREALGEDDPQAGEALGAKELGQETMGLEEAEGMWEESVDLQEEHRDLQEGHGDLQVEHEDLWEEHGHIQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHGDLQVEHEDLQVEHGDLQVEHEDLWEEHRDVQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHEDLQEEHGDTQEEHGDLQEEHGDLQVEHEDLQVEHGDLQVEHGDLQEEHGDTQEEHRDLQEVHGDQQEEHRDLQEEHGDLQKGHGDLQGEHGDLQVEHGDLQDEYGDTQEEHRDLQEVHGDQQEEHRNLQEGHGDLQEGHGDLWKEHGVLKEEHGDLQERHGDLQEESGDPQEEPGEPWVQHGEQGSAGDGLEQDMVLQPGEGAWGREDNDISQKQQAQDWEGTAEDEEETGVNTITSQEPTQVDDNPHAEAAENEERDVTSPTAMEETQEGEDEGDAGSEVQSQQQPQDTPGQEAELAPGQKEVRYGDTGEAPGDPQEPAEALEVEDEELSSEPIELERGSPDTAVMQQDLGNGAESDEPMEEDFQSEDAQLEEPKACRMELEDTLLNSTPLCAYSGEMLESDPNPPSSGGDGEAAPEMAQEEEGELRGSDEATVHAEPESCEELSPAPQCTEEEEGYFIVSAPSQEGSSMEEAENSEEFEEIKVEAAEDRKDELTAPGVASLVPEDEGHSEPFVGEAEDVKMPLGEFEMPKEEDEEDAGGFAAELEEGLTVPVAEGLSEGHTDNTTLGDEGLGEEDEQDGDNPPATETSNTDPSNTDPPPGTMLEHGAGMEAAEYLPDVPTQLPVDIMKDSDILEIVEQALEFNQELVLGAKLAKDGQEEDGDAQPPQEEEGGSSPTSSSDEQPTVQEAVAEPERTKNGEQNGLHRQASLEDLAEFTEEGLNGITHPGEAPAAHTLPLPSKHSGAEPVPELSPLQDHVLRPEQEPWSSGEE", "length": 1670, "header": "tr|A0A8V1AIC5-1|A0A8V1AIC5_CHICK Computationally mapped isoform of Nestin OS=Gallus gallus OX=9031 GN=NES PE=1 SV=1 CANONICAL=A0A8V1AG21-1" }, "locus": { "chromosome": "25", "start_pos": 1016896, "end_pos": 1009717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068672.1", "url": "https://www.ensembl.org/id/ENSGALT00010068672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042210.1", "url": "https://www.ensembl.org/id/ENSGALP00010042210.1" } ] } }, { "isoform_ac": "A0A8V1AK65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG21/entry#A0A8V1AK65-1", "sequence": { "sequence": "MLSMEGFVGARALGEESLQMWDLNKRLEAYLARVKFLEEENEGLRAEIQSTKENPAGDPRRARYEEELRSLRDALHRAFTEKCAAELARDNLYEEVQHVRSRCQKEQAAREEAKRQLSSSKKELEEERRAQIWLKERAVQLEKEVEALLEVHEEEKAGLDQELASFSQSLEGFRCAPVAFQPVEVEDYSKRLSEIWRGAVETYKAEVSQLERALGQAKENLWQVAEDNQQSQLQLRHLEKELVGLKVRKEMLEESLGQQWQEQHGEAEKFQLAIEALEQEKQSLQVQIAQVLEDRQQLMHLKMSLSLEVATYRTLLEAESTRLQMPPGEFKLANSLRDVKLEASSSKHRASLAAFPRPEGVAQLCRTPGDALKVLTPKSKSSSALEFQKISSVLQAPRSWEPAAPSPTVPVLSPEPGSGGAESPVHECGAGKESPMLSPLSPEQLVSHALQDALKEMQDDAEAKEVPTLSATQSTRDGDLEATMEEEEAAGTQGVGAEGETVSPPGLCLCSNEPTLLSATQSDAESQEEMWEEERSKEEMLNPLSSMESQEPGGEPWGGDTRGSRLQVGKEDMEATSTEALHVSEKKEQREIWSPSREDEECEFPDEEREMQEEGSLQMEIEAACAVPVGSHPVLPTGIHLQEDFLEREQESEHQEMSLGELGAAAGEEREQEVCQELKASSIEEAMPAAEGSSGSGEDTTGRESTGRARDDEGEEEDKGREALGEDDPQAGEALGAKELGQETMGLEEAEGMWEESVDLQEEHRDLQEGHGDLQVEHEDLWEEHGHIQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHGDLQVEHEDLQVEHGDLQVEHEDLWEEHRDVQEEHGDTQEEYGDTQEEHGDLQVEGGDLQEEHGDTQEEHEDLQEEHGDTQEEHGDLQVEHGDLQEEHRDLQEGHGDLKEEHGDLQVEHEDLQVEHGDLQVEHGDLQEEHGDTQEEHGDTQEEHGDLQEEHGDLQEEHGDLQEEHGDLQVEHGDLQEEHGDTQEEHRDLQEVHGDQQEEHRNLQEGHGDLQEGHGDLWKEHGVLKEEHGDLQERHGDLQEESGDPQEEPGEPWVQHGEQGSAGDGLEQDMVLQPGEGAWGREDNDISQKQQAQDWEGTAEDEEETGVNTITSQEPTQVDDNPHAEAAENEERDVTSPTAMEETQEGEDEGDAGSEVQSQQQPQDTPGQEAELAPGQKEVRYGDTGEAPGDPQEPAEALEVEDEELSSEPIELERGSPDTAVMQQDLGNGAESDEPMEEDFQSEDAQLEEPKACRMELEDTLLNSTPLCAYSGEMLESDPNPPSSGGDGEAAPEMAQEEEGELRGSDEATVHAEPESCEELSPAPQCTEEEEGYFIVSAPSQEGSSMEEAENSEEFEEIKVEAAEDRKDELTAPGVASLVPEDEGHSEPFVGEAEDVKMPLGEFEMPKEEDEEDAGGFAAELEEGLTVPVAEGLSEGHTDNTTLGDEGLGEEDEQDGDNPPATETSNTDPSNTDPPPGTMLEHGAGMEAAEYLPDVPTQLPVDIMKDSDILEIVEQALEFNQELVLGAKLAKDGQEEDGDAQPPQEEEGGSSPTSSSDEQPTVQEAVAEPERTKNGEQNGLHRQASLEDLAEFTEEGLNGITHPGEAPAAHTLPLPSKHSGAEPVPELSPLQDHVLRPEQEPWSSGEE", "length": 1684, "header": "tr|A0A8V1AK65-1|A0A8V1AK65_CHICK Computationally mapped isoform of Nestin OS=Gallus gallus OX=9031 GN=NES PE=1 SV=1 CANONICAL=A0A8V1AG21-1" }, "locus": { "chromosome": "25", "start_pos": 1016896, "end_pos": 1009717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068670.1", "url": "https://www.ensembl.org/id/ENSGALT00010068670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042208.1", "url": "https://www.ensembl.org/id/ENSGALP00010042208.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1646, "start_aa": "Thr", "end_pos": 1646, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1646", "evidence": [ { "id": "GLY_001161", 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"id": "EWNWNIS", "url": "https://omabrowser.org/oma/group/EWNWNIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAR9", "url": "https://www.orthodb.org/?gene=A0A8V1AAR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG39", "url": "https://www.orthodb.org/?gene=A0A8V1AG39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKD1", "url": "https://www.orthodb.org/?gene=A0A8V1AKD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM44", "url": "https://www.orthodb.org/?gene=A0A8V1AM44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13713", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13713", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13713:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13713:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AAR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACRATCYEGNGSRAACYMTAGCKEDERTWPRTSARQDLPAELKKYTCSNFCPDHVGLCVKSLYHVTNTLGRHIENGALYRVFGGDPFMDTGGQELESRTTWRHVGACRRRFMWRKPFLSRFESHWEPFLTSKSIYSLLDRPFKQELEEVLWLHKLPFGLHSSVLSAFSTLQLLPEQDLPGSFGRLWCQRCIVVGNGYSVHGQHFGKMIDSHHVIIRLNDAPVKEYKKDVGERTSIRLFFPESALPNPLENSDNNTLMVFVPFKPLDFLWLREVLLKTKNKTTEGFWRQPPQEWNWNISQLRILNPYVTYEATYKLLQLNASSKRYATTGIIALNLALHLCQEVNIAGFGYPGNHDTTTPIHYYNTGLSRKNELFQHNLTAERNWLLKMIEWGVIADLTSHAFQAQNH", "length": 408, "header": "tr|A0A8V1AG39-1|A0A8V1AG39_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=ST3GAL9 PE=3 SV=1 CANONICAL=A0A8V1AG39-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39/entry#A0A8V1AAR9-1", "sequence": { "sequence": "MMKEPFPAASAVPNSCMWSRALRASQASLPSAGLCVKSLYHVTNTLGRHIENGALYRVFGGDPFMDTGGQELESRTTWRHVGACRRRFMWRKPFLSRFESHWEPFLTSKSIYSLLDRPFKQELEEVLWLHKLPFGLHSSVLSAFSTLQLLPEQDLPGSFGRLWCQRCIVVGNGYSVHGQHFGKMIDSHHVIIRLNDAPVKEYKKDVGERTSIRLFFPESALPNPLENSDNNTLMVFVPFKPLDFLWLREVLLKTKNKTTEGFWRQPPQEWNWNISQLRILNPYVTYEATYKLLQLNASSKRYATTGIIALNLALHLCQEVNIAGFGYPGNHDTTTPIHYYNTGLSRKNELFQHNLTAERNWLLKMIEWGVIADLTSHAFQAQNH", "length": 384, "header": "tr|A0A8V1AAR9-1|A0A8V1AAR9_CHICK Computationally mapped isoform of ST3 beta-galactoside alpha-2,3-sialyltransferase 4 OS=Gallus gallus OX=9031 GN=ST3GAL9 PE=3 SV=1 CANONICAL=A0A8V1AG39-1" }, "locus": { "chromosome": "17", "start_pos": 4240036, "end_pos": 4233430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069948.1", "url": "https://www.ensembl.org/id/ENSGALT00010069948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043074.1", "url": "https://www.ensembl.org/id/ENSGALP00010043074.1" } ] } }, { "isoform_ac": "A0A8V1AG39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39/entry#A0A8V1AG39-1", "sequence": { "sequence": "MACRATCYEGNGSRAACYMTAGCKEDERTWPRTSARQDLPAELKKYTCSNFCPDHVGLCVKSLYHVTNTLGRHIENGALYRVFGGDPFMDTGGQELESRTTWRHVGACRRRFMWRKPFLSRFESHWEPFLTSKSIYSLLDRPFKQELEEVLWLHKLPFGLHSSVLSAFSTLQLLPEQDLPGSFGRLWCQRCIVVGNGYSVHGQHFGKMIDSHHVIIRLNDAPVKEYKKDVGERTSIRLFFPESALPNPLENSDNNTLMVFVPFKPLDFLWLREVLLKTKNKTTEGFWRQPPQEWNWNISQLRILNPYVTYEATYKLLQLNASSKRYATTGIIALNLALHLCQEVNIAGFGYPGNHDTTTPIHYYNTGLSRKNELFQHNLTAERNWLLKMIEWGVIADLTSHAFQAQNH", "length": 408, "header": "tr|A0A8V1AG39-1|A0A8V1AG39_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=ST3GAL9 PE=3 SV=1 CANONICAL=A0A8V1AG39-1" }, "locus": { "chromosome": "17", "start_pos": 4240036, "end_pos": 4225506, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069950.1", "url": "https://www.ensembl.org/id/ENSGALT00010069950.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043076.1", "url": "https://www.ensembl.org/id/ENSGALP00010043076.1" } ] } }, { "isoform_ac": "A0A8V1AKD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39/entry#A0A8V1AKD1-1", "sequence": { "sequence": "MQASVTNTAWMGAGWGRRQDLPAELKKYTCSNFCPDHVGLCVKSLYHVTNTLGRHIENGALYRVFGGDPFMDTGGQELESRTTWRHVGACRRRFMWRKPFLSRFESHWEPFLTSKSIYSLLDRPFKQELEEVLWLHKLPFGLHSSVLSAFSTLQLLPEQDLPGSFGRLWCQRCIVVGNGYSVHGQHFGKMIDSHHVIIRLNDAPVKEYKKDVGERTSIRLFFPESALPNPLENSDNNTLMVFVPFKPLDFLWLREVLLKTKNKTTEGFWRQPPQEWNWNISQLRILNPYVTYEATYKLLQLNASSKRYATTGIIALNLALHLCQEVNIAGFGYPGNHDTTTPIHYYNTGLSRKNELFQHNLTAERNWLLKMIEWGVIADLTSHAFQAQNH", "length": 390, "header": "tr|A0A8V1AKD1-1|A0A8V1AKD1_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=ST3GAL9 PE=3 SV=1 CANONICAL=A0A8V1AG39-1" }, "locus": { "chromosome": "17", "start_pos": 4240036, "end_pos": 4225355, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069951.1", "url": "https://www.ensembl.org/id/ENSGALT00010069951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043077.1", "url": "https://www.ensembl.org/id/ENSGALP00010043077.1" } ] } }, { "isoform_ac": "A0A8V1AM44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39/entry#A0A8V1AM44-1", "sequence": { "sequence": "MGNFPDLPAELKKYTCSNFCPDHVGLCVKSLYHVTNTLGRHIENGALYRVFGGDPFMDTGGQELESRTTWRHVGACRRRFMWRKPFLSRFESHWEPFLTSKSIYSLLDRPFKQELEEVLWLHKLPFGLHSSVLSAFSTLQLLPEQDLPGSFGRLWCQRCIVVGNGYSVHGQHFGKMIDSHHVIIRLNDAPVKEYKKDVGERTSIRLFFPESALPNPLENSDNNTLMVFVPFKPLDFLWLREVLLKTKNKTTEGFWRQPPQEWNWNISQLRILNPYVTYEATYKLLQLNASSKRYATTGIIALNLALHLCQEVNIAGFGYPGNHDTTTPIHYYNTGLSRKNELFQHNLTAERNWLLKMIEWGVIADLTSHAFQAQNH", "length": 376, "header": "tr|A0A8V1AM44-1|A0A8V1AM44_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=ST3GAL9 PE=3 SV=1 CANONICAL=A0A8V1AG39-1" }, "locus": { "chromosome": "17", "start_pos": 4240036, "end_pos": 4227118, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069949.1", "url": "https://www.ensembl.org/id/ENSGALT00010069949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043075.1", "url": "https://www.ensembl.org/id/ENSGALP00010043075.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39" } ], "pmid": "" }, { "name": "glycolipid biosynthetic process", "id": "GO:0009247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009247", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase", "id": "GO:0047288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39" } ], "pmid": "" }, { "name": "beta-galactoside (CMP) alpha-2,3-sialyltransferase activity", "id": "GO:0003836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003836", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39" } ], "pmid": "" }, { "name": "sialyltransferase activity", "id": "GO:0008373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008373", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AG62-1", "uniprot_ac": "A0A8V1AG62", "uniprot_id": "A0A8V1AG62_CHICK", "mass": { "chemical_mass": 19996.0, "monoisotopic_mass": 19996.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AG62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG62/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AG62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG62", "locus": {} } ], "crossref": [ { "id": "A0A8V1AG62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AG62", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AG62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYIIYLKLYQAPLKKSERVLRAVPISPYPHPYIPIPLHPYILTSLHPYITTSLHPYIAIPPPPCILISPHLHISISPHPHIPISPYPHTPFPSSQQRRAVGPSSSHPCPSSIGLPCPSCCGAHVGWWPHGATGAGTDAFPGRFPAKLLLGLLIFTEITCCERRRVYGPLTNRKPRASAGCKS", "length": 182, "header": "tr|A0A8V1AG62-1|A0A8V1AG62_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AG62-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AG62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG62/entry#A0A8V1AG62-1", "sequence": { "sequence": "MYIIYLKLYQAPLKKSERVLRAVPISPYPHPYIPIPLHPYILTSLHPYITTSLHPYIAIPPPPCILISPHLHISISPHPHIPISPYPHTPFPSSQQRRAVGPSSSHPCPSSIGLPCPSCCGAHVGWWPHGATGAGTDAFPGRFPAKLLLGLLIFTEITCCERRRVYGPLTNRKPRASAGCKS", "length": 182, "header": "tr|A0A8V1AG62-1|A0A8V1AG62_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AG62-1" }, "locus": { "chromosome": "17", "start_pos": 8749720, "end_pos": 8749175, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069975.1", "url": "https://www.ensembl.org/id/ENSGALT00010069975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043101.1", "url": "https://www.ensembl.org/id/ENSGALP00010043101.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"MCPKLCTSGTTSSPSAAARPSSSFSSWRLRGDAVRAALRAVPANPAPPLPVGVRRPQRLQRRRVGKRVLVLQQQPGGAHSAEQRQHLRSGSGRAVGAGRAERSPLPPPFSPHLGQVRGAGRSALQVQVHQALPHRARWLRPLSLLPALCPGSLSAARRAHRSAVAAMAAVAARRRTGGGERRRQGSARRNAGPLEARGGRLWAACFVSAALVAAAGGLLAWSSRSAEDGVAEVLARRGETLLDKFVEVPCSGDYDGYRRFEGCTPRRCGRGVSDVVITREEAERIRRVAERGLSLGGSDGGASILDLHSGALSLGKQFVNLYRYFGDKIQGIFTEEDFALYRDVRQRIQQKIAQAFGISSSSMYLTKPTFFSRINSTEAKTTHDEYWHPHIDKVTYGSFDYTSLLYLSDYAEDFGGGRFVFMDAGSNKTIEPQAGRVSFFTSGSENLHRVEKVHWGTRYAITISFTCNPDHGIGDPVLM", "length": 479, "header": "tr|A0A8V1AGA3-1|A0A8V1AGA3_CHICK Isoform 1 of 2-oxoglutarate and iron dependent oxygenase domain containing 3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA3/entry#A0A8V1AGA3-1", "sequence": { "sequence": "MCPKLCTSGTTSSPSAAARPSSSFSSWRLRGDAVRAALRAVPANPAPPLPVGVRRPQRLQRRRVGKRVLVLQQQPGGAHSAEQRQHLRSGSGRAVGAGRAERSPLPPPFSPHLGQVRGAGRSALQVQVHQALPHRARWLRPLSLLPALCPGSLSAARRAHRSAVAAMAAVAARRRTGGGERRRQGSARRNAGPLEARGGRLWAACFVSAALVAAAGGLLAWSSRSAEDGVAEVLARRGETLLDKFVEVPCSGDYDGYRRFEGCTPRRCGRGVSDVVITREEAERIRRVAERGLSLGGSDGGASILDLHSGALSLGKQFVNLYRYFGDKIQGIFTEEDFALYRDVRQRIQQKIAQAFGISSSSMYLTKPTFFSRINSTEAKTTHDEYWHPHIDKVTYGSFDYTSLLYLSDYAEDFGGGRFVFMDAGSNKTIEPQAGRVSFFTSGSENLHRVEKVHWGTRYAITISFTCNPDHGIGDPVLM", "length": 479, "header": "tr|A0A8V1AGA3-1|A0A8V1AGA3_CHICK Isoform 1 of 2-oxoglutarate and iron dependent oxygenase domain containing 3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGA3-1" }, "locus": { "chromosome": "18", "start_pos": 4174073, "end_pos": 4140084, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070450.1", "url": "https://www.ensembl.org/id/ENSGALT00010070450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043141.1", "url": "https://www.ensembl.org/id/ENSGALP00010043141.1" } ] } }, { "isoform_ac": "A0A8V1AM93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA3/entry#A0A8V1AM93-1", "sequence": { "sequence": "RGAAAAPEERQRAGSGRRPGRALPSPTSLLPSPRPAHGGTRARWRRAAGGCGRRASFPPLSSRPPAVSWRGAPGALRTASPRCWPGAGRRCSTSSWRCRAPGTTTATGGLKASILDLHSGALSLGKQFVNLYRYFGDKIQGIFTEEDFALYRDVRQRIQQKIAQAFGISSSSMYLTKPTFFSRINSTEAKTTHDEYWHPHIDKVTYGSFDYTSLLYLSDYAEDFGGGRFVFMDAGSNKTIEPQAGRVSFFTSGSENLHRVEKVHWGTRYAITISFTCNPDHGIGDPVLM", "length": 289, "header": "tr|A0A8V1AM93-1|A0A8V1AM93_CHICK Computationally mapped isoform of 2-oxoglutarate and iron dependent oxygenase domain containing 3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGA3-1" }, "locus": { "chromosome": "18", "start_pos": 4174073, "end_pos": 4140323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070449.1", "url": "https://www.ensembl.org/id/ENSGALT00010070449.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043140.1", "url": "https://www.ensembl.org/id/ENSGALP00010043140.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA3" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA3" } ], "pmid": "" }, { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA3" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA3" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3Z5", "url": "https://www.orthodb.org/?gene=A0A8V1A3Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGB1", "url": "https://www.orthodb.org/?gene=A0A8V1AGB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGB5", "url": "https://www.orthodb.org/?gene=A0A8V1AGB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21333", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21333", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2473224", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2473224", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NZN4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLRLALCLLVLCSLAGGDAAHGGICWLQQGKEAKCTMILKTGVTWEECCANGNVDVAWSNYTYPGNKISLLGFLGLVTCHPCKESCEGVVCGPDKVCKMKHGRPQCACAPDCSSLPRKLQVCGSDGYTYRDECDLLTAKCRDHPDLEVMYQGKCKKSCSSVVCPGTHTCVVDQTGSAHCVMCRTAPCPEPTSLDHSLCGNNNVTYPSACHLRRATCHLGRSIGVRHYGSCSGERGRERRPSMGLCGAVPLLYSLSTPFPLLSPPPHPLQPRPGSPWRRTTRRRTTCESFLRRKAAAGRQGHYVYTVQTIYLIFIKIKRSLFISLCYADAERRLLAVPAHIPCAAPCPGRASGERLHCCTPSPPPHNVSLDGRPGPIYFWIEFLVLC", "length": 387, "header": "tr|A0A8V1AGB5-1|A0A8V1AGB5_CHICK Isoform 1 of Follistatin-related protein 3 OS=Gallus gallus OX=9031 GN=FSTL3 PE=4 SV=1 CANONICAL=A0A8V1AGB5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5/entry#A0A1D5NZN4-1", "sequence": { "sequence": "MPLRLALCLLVLCSLAGGDAAHGGICWLQQGKEAKCTMILKTGVTWEECCANGNVDVAWSNYTYPGNKISLLGFLGLVTCHPCKESCEGVVCGPDKVCKMKHGRPQCACAPDCSSLPRKLQVCGSDGYTYRDECDLLTAKCRDHPDLEVMYQGKCKKSCSSVVCPGTHTCVVDQTGSAHCVMCRTAPCPEPTSLDHSLCGNNNVTYPSACHLRRATCHLGRSIGVRHYGSCSASARFSMETDNAEENYV", "length": 249, "header": "tr|A0A1D5NZN4-1|A0A1D5NZN4_CHICK Computationally mapped isoform of Follistatin-related protein 3 OS=Gallus gallus OX=9031 GN=FSTL3 PE=4 SV=1 CANONICAL=A0A8V1AGB5-1" }, "locus": { "chromosome": "28", "start_pos": 3179744, "end_pos": 3172446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066343.1", "url": "https://www.ensembl.org/id/ENSGALT00010066343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040609.1", "url": "https://www.ensembl.org/id/ENSGALP00010040609.1" } ] } }, { "isoform_ac": "A0A8V1A3Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5/entry#A0A8V1A3Z5-1", "sequence": { "sequence": "MVPPWGLMGAPCAGRGVLEGGICWLQQGKEAKCTMILKTGVTWEECCANGNVDVAWSNYTYPGNKISLLGFLGLVTCHPCKESCEGVVCGPDKVCKMKHGRPQCACAPDCSSLPRKLQVCGSDGYTYRDECDLLTAKCRDHPDLEVMYQGKCKKSCSSVVCPGTHTCVVDQTGSAHCVMCRTAPCPEPTSLDHSLCGNNNVTYPSACHLRRATCHLGRSIGVRHYGSCSASARFSMETDNAEENYV", "length": 246, "header": "tr|A0A8V1A3Z5-1|A0A8V1A3Z5_CHICK Computationally mapped isoform of Follistatin-related protein 3 OS=Gallus gallus OX=9031 GN=FSTL3 PE=4 SV=1 CANONICAL=A0A8V1AGB5-1" }, "locus": { "chromosome": "28", "start_pos": 3179744, "end_pos": 3175552, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066340.1", "url": "https://www.ensembl.org/id/ENSGALT00010066340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040606.1", "url": "https://www.ensembl.org/id/ENSGALP00010040606.1" } ] } }, { "isoform_ac": "A0A8V1AGB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5/entry#A0A8V1AGB1-1", "sequence": { "sequence": "MWVREWGWSRSWELRGLGKEAKCTMILKTGVTWEECCANGNVDVAWSNYTYPGNKISLLGFLGLVTCHPCKESCEGVVCGPDKVCKMKHGRPQCACAPDCSSLPRKLQVCGSDGYTYRDECDLLTAKCRDHPDLEVMYQGKCKKSCSSVVCPGTHTCVVDQTGSAHCVMCRTAPCPEPTSLDHSLCGNNNVTYPSACHLRRATCHLGRSIGVRHYGSCSASARFSMETDNAEENYV", "length": 236, "header": "tr|A0A8V1AGB1-1|A0A8V1AGB5_CHICK Computationally mapped isoform of Follistatin-related protein 3 OS=Gallus gallus OX=9031 GN=FSTL3 PE=4 SV=1 CANONICAL=A0A8V1AGB5-1" }, "locus": { "chromosome": "28", "start_pos": 3179744, "end_pos": 3173705, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066341.1", "url": "https://www.ensembl.org/id/ENSGALT00010066341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040607.1", "url": "https://www.ensembl.org/id/ENSGALP00010040607.1" } ] } }, { "isoform_ac": "A0A8V1AGB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5/entry#A0A8V1AGB5-1", "sequence": { "sequence": "MPLRLALCLLVLCSLAGGDAAHGGICWLQQGKEAKCTMILKTGVTWEECCANGNVDVAWSNYTYPGNKISLLGFLGLVTCHPCKESCEGVVCGPDKVCKMKHGRPQCACAPDCSSLPRKLQVCGSDGYTYRDECDLLTAKCRDHPDLEVMYQGKCKKSCSSVVCPGTHTCVVDQTGSAHCVMCRTAPCPEPTSLDHSLCGNNNVTYPSACHLRRATCHLGRSIGVRHYGSCSGERGRERRPSMGLCGAVPLLYSLSTPFPLLSPPPHPLQPRPGSPWRRTTRRRTTCESFLRRKAAAGRQGHYVYTVQTIYLIFIKIKRSLFISLCYADAERRLLAVPAHIPCAAPCPGRASGERLHCCTPSPPPHNVSLDGRPGPIYFWIEFLVLC", "length": 387, "header": "tr|A0A8V1AGB5-1|A0A8V1AGB5_CHICK Isoform 1 of Follistatin-related protein 3 OS=Gallus gallus OX=9031 GN=FSTL3 PE=4 SV=1 CANONICAL=A0A8V1AGB5-1" }, "locus": { "chromosome": "28", "start_pos": 3180045, "end_pos": 3172446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066346.1", "url": "https://www.ensembl.org/id/ENSGALT00010066346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040612.1", "url": "https://www.ensembl.org/id/ENSGALP00010040612.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770427", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770427", "resource": "KEGG Pathway" }, { "id": "R-GGA-2473224", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2473224", "resource": "Reactome", "description": "Antagonism of Activin by Follistatin" }, { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "O95633-1", "protein_name": "Follistatin-related protein 3", "gene_name": "FSTL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPGAPGPLWPLPWGALAWAVGFVSSMGSGNPAPGGVCWLQQGQEATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKINLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPGGESAEEEENFV", "length": 263 }, "evidence": [ { "id": "A0A8V1AGB5", "url": "https://omabrowser.org/oma/group/A0A8V1AGB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LZB9-1", "protein_name": "Follistatin-related protein 3", "gene_name": "FSTL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRPRAPGPLWPLPWGALAWAVGFVGSLGSGDPAPGGVCWLQQGREATCSLVLKTDVSQAECCASGNIDTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCEGVECGPGKACRMLGGRPRCECAPDCTGLPARLQVCGSDGATYRDECELRAARCRGHPDLRVMYRGRCRKSCAHVVCLRPQSCVVDQTGSAHCVVCRAAPCPAPSSPGQELCGNNNVTYLSSCHLRQATCFLGRSIGVRHPGSCAGTPEPLDPESEEEENFV", "length": 261 }, "evidence": [ { "id": "A0A8V1AGB5", "url": "https://omabrowser.org/oma/group/A0A8V1AGB5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99PW7-1", "protein_name": "Follistatin-related protein 3", "gene_name": "Fstl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPGALWPLLWGALVWAVGSVGAVMGSGDSVPGGVCWLQQGKEATCSLVLKTQVSREECCASGNINTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPHCECVSNCEGVPAGFQVCGSDGATYRDECELRTARCRGHPDLRVMYRGRCQKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPPNPGQELCGNNNVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVPAEEEENFV", "length": 256 }, "evidence": [ { "id": "A0A8V1AGB5", "url": "https://omabrowser.org/oma/group/A0A8V1AGB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9EQC7-1", "protein_name": "Follistatin-related protein 3", "gene_name": "Fstl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSGALWPLLWGALVWTVGSVGAVMGSEDSVPGGVCWLQQGREATCSLVLKTRVSREECCASGNINTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPHCECVPNCEGLPAGFQVCGSDGATYRDECELRTARCRGHPDLRVMYRGRCQKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPSNPGQELCGNNNVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVPAEEEENFV", "length": 256 }, "evidence": [ { "id": "A0A8V1AGB5", "url": "https://omabrowser.org/oma/group/A0A8V1AGB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" }, { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" }, { "name": "negative regulation of activin receptor signaling pathway", "id": "GO:0032926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032926", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" }, { "name": "regulation of BMP signaling pathway", "id": "GO:0030510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030510", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "activin binding", "id": "GO:0048185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048185", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 157, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AGB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB5" }, { "id": "PS51364", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51364" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 83, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGB3-1", "uniprot_ac": "A0A8V1AGB3", "uniprot_id": "A0A8V1AGB3_CHICK", "mass": { "chemical_mass": 36318.0, "monoisotopic_mass": 36318.0 }, "refseq": { "ac": "NP_001335501", "name": "T-cell antigen CD7 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335501" }, "gene_names": [ { "name": "CD7", "type": "recommended", "evidence": [ { "id": "A0A8V1AGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3" } ] }, { "name": "CD7", "type": "synonym", "evidence": [ { "id": "NP_001335501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335501" } ] } ], "protein_names": [ { "name": "CD7 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V1AGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3/entry#names_and_taxonomy" } ] }, { "name": "T-cell antigen CD7 precursor", "type": "synonym", "evidence": [ { "id": "NP_001335501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335501" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888547.212667.1, SRR12888544.140982.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000316.1. On Dec 3, 2021 this sequence version replaced NP_001335501.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001335501", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335501" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3", "locus": { "chromosome": "18", "start_pos": 4338060, "end_pos": 4329400, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029158", "url": "https://www.ensembl.org/id/ENSGALG00010029158" } ] } } ], "crossref": [ { "id": "A0A8V1AGB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00099", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00099", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417346", "url": "https://www.ncbi.nlm.nih.gov/gene/417346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417346", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AGB3", "url": "https://www.orthodb.org/?gene=A0A8V1AGB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15343:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15343:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001335501", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335501", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQWTSPLPFVYLLFLLLPFFRGQNGEENKITDWSTDIISVWEGDTINLTCSKNSSENEVGTQLRIRAPPTNIIYFSTKYAPYIDPAFANRTKYLNEGTNLTITVHNVQKSDSNIYLCIHYSVVNERHFKEFGKAVILVVKAKSSGVIEQSPLSVHAQQGESINITCVLKSSNEDEEIMLLRLHRQLEKVLYVLSQKTTTISPTFANRLEYSKQEKKLVITLHNLQENDTDIYVCAAVLKNSSFSVSESGTMVLVKGEKQTACSISSLAIYIPIIVVALLLSALICFILNRINKKKFVQKRKIDGVYEDMSFSSRSNTLVRN", "length": 321, "header": "tr|A0A8V1AGB3-1|A0A8V1AGB3_CHICK Isoform 1 of CD7 molecule OS=Gallus gallus OX=9031 GN=CD7 PE=4 SV=1 CANONICAL=A0A8V1AGB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3/entry#A0A8V1AGB3-1", "sequence": { "sequence": "MQWTSPLPFVYLLFLLLPFFRGQNGEENKITDWSTDIISVWEGDTINLTCSKNSSENEVGTQLRIRAPPTNIIYFSTKYAPYIDPAFANRTKYLNEGTNLTITVHNVQKSDSNIYLCIHYSVVNERHFKEFGKAVILVVKAKSSGVIEQSPLSVHAQQGESINITCVLKSSNEDEEIMLLRLHRQLEKVLYVLSQKTTTISPTFANRLEYSKQEKKLVITLHNLQENDTDIYVCAAVLKNSSFSVSESGTMVLVKGEKQTACSISSLAIYIPIIVVALLLSALICFILNRINKKKFVQKRKIDGVYEDMSFSSRSNTLVRN", "length": 321, "header": "tr|A0A8V1AGB3-1|A0A8V1AGB3_CHICK Isoform 1 of CD7 molecule OS=Gallus gallus OX=9031 GN=CD7 PE=4 SV=1 CANONICAL=A0A8V1AGB3-1" }, "locus": { "chromosome": "18", "start_pos": 4336505, "end_pos": 4330042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070460.1", "url": "https://www.ensembl.org/id/ENSGALT00010070460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043151.1", "url": "https://www.ensembl.org/id/ENSGALP00010043151.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417346", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGB3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 117, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 89, "end_pos": 91 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGC1-1", "uniprot_ac": "A0A8V1AGC1", "uniprot_id": "A0A8V1AGC1_CHICK", "mass": { "chemical_mass": 38652.0, "monoisotopic_mass": 38652.0 }, "refseq": {}, "gene_names": [ { "name": "MED27", "type": "recommended", "evidence": [ { "id": "A0A8V1AGC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ] } ], "protein_names": [ { "name": "Mediator complex subunit 27", "type": "synonym", "evidence": [ { "id": "A0A8V1AGC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MED27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1", "locus": { "chromosome": "17", "start_pos": 6940772, "end_pos": 7022744, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028438", "url": "https://www.ensembl.org/id/ENSGALG00010028438" } ] } } ], "crossref": [ { "id": "A0A8V1AGC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR021627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8N9", "url": "https://www.orthodb.org/?gene=A0A8V1A8N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGC1", "url": "https://www.orthodb.org/?gene=A0A8V1AGC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIL5", "url": "https://www.orthodb.org/?gene=A0A8V1AIL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13130:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13130:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9841922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8N9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAAAAGLHFPACPAPPRCCRPRREGAVRAKMAEGVLSPGVNLEAFSQAIAAIQALRSSVTRVFDCLKDGMRNKETLEGREKGFVAAFQESLHSVSRDLGELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVINRIDRMFPEMSIQLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTDDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFRTLEAFHDTCRQ", "length": 344, "header": "tr|A0A8V1AGC1-1|A0A8V1AGC1_CHICK Isoform 1 of Mediator complex subunit 27 OS=Gallus gallus OX=9031 GN=MED27 PE=3 SV=1 CANONICAL=A0A8V1AGC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1/entry#A0A8V1A8N9-1", "sequence": { "sequence": "MPRAAAAGLHFPACPAPPRCCRPRREGAVRAKMAEGVLSPGVNLEAFSQAIAAIQALRSSVTRVFDCLKDGMRNKETLEGREKGFVAAFQESLHSVSRDLGELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVINRIDRMFPEMSIQLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTDDGKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFRTLEAFHDTCRQ", "length": 330, "header": "tr|A0A8V1A8N9-1|A0A8V1A8N9_CHICK Computationally mapped isoform of Mediator complex subunit 27 OS=Gallus gallus OX=9031 GN=MED27 PE=3 SV=1 CANONICAL=A0A8V1AGC1-1" }, "locus": { "chromosome": "17", "start_pos": 7022545, "end_pos": 6941974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068878.1", "url": "https://www.ensembl.org/id/ENSGALT00010068878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042320.1", "url": "https://www.ensembl.org/id/ENSGALP00010042320.1" } ] } }, { "isoform_ac": "A0A8V1AGC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1/entry#A0A8V1AGC1-1", "sequence": { "sequence": "MPRAAAAGLHFPACPAPPRCCRPRREGAVRAKMAEGVLSPGVNLEAFSQAIAAIQALRSSVTRVFDCLKDGMRNKETLEGREKGFVAAFQESLHSVSRDLGELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVINRIDRMFPEMSIQLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTDDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFRTLEAFHDTCRQ", "length": 344, "header": "tr|A0A8V1AGC1-1|A0A8V1AGC1_CHICK Isoform 1 of Mediator complex subunit 27 OS=Gallus gallus OX=9031 GN=MED27 PE=3 SV=1 CANONICAL=A0A8V1AGC1-1" }, "locus": { "chromosome": "17", "start_pos": 7022545, "end_pos": 6941974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068877.1", "url": "https://www.ensembl.org/id/ENSGALT00010068877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042319.1", "url": "https://www.ensembl.org/id/ENSGALP00010042319.1" } ] } }, { "isoform_ac": "A0A8V1AIL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1/entry#A0A8V1AIL5-1", "sequence": { "sequence": "MAEGVLSPGVNLEAFSQAIAAIQALRSSVTRVFDCLKDGMRNKETLEGREKGFVAAFQESLHSVSRDLGELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVINRIDRMFPEMSIQLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTDDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMVRHAYLLCLFLCLFNKKATKMRAVQRTFL", "length": 297, "header": "tr|A0A8V1AIL5-1|A0A8V1AIL5_CHICK Computationally mapped isoform of Mediator complex subunit 27 OS=Gallus gallus OX=9031 GN=MED27 PE=3 SV=1 CANONICAL=A0A8V1AGC1-1" }, "locus": { "chromosome": "17", "start_pos": 7022449, "end_pos": 6943492, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068876.1", "url": "https://www.ensembl.org/id/ENSGALT00010068876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042318.1", "url": "https://www.ensembl.org/id/ENSGALP00010042318.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGE2-1", "uniprot_ac": "A0A8V1AGE2", "uniprot_id": "A0A8V1AGE2_CHICK", "mass": { "chemical_mass": 42833.0, "monoisotopic_mass": 42833.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM59L", "type": "recommended", "evidence": [ { "id": "A0A8V1AGE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2" } ] } ], "protein_names": [ { "name": "Transmembrane protein 59 like", "type": "synonym", "evidence": [ { "id": "A0A8V1AGE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM59L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2", "locus": { "chromosome": "28", "start_pos": 4317034, "end_pos": 4327699, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028451", "url": "https://www.ensembl.org/id/ENSGALG00010028451" } ] } } ], "crossref": [ { "id": "A0A8V1AGE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "420122", "url": "https://www.ncbi.nlm.nih.gov/gene/420122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420122", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420122", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DNAHKVN", "url": "https://omabrowser.org/oma/group/DNAHKVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGE2", "url": "https://www.orthodb.org/?gene=A0A8V1AGE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKG7", "url": "https://www.orthodb.org/?gene=A0A8V1AKG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28652:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28652:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GLREKRETLRSVSESSDAFIGARGDRKRRLLRRTKGDLGGAEKKLKRNGCEATGPRPAALPPSRPLLRRWRFWCPSLGSRHSSAELRSLKGDLAASVPALPHVGAAGRNSDRGTKEDAVLSACYRGCRLFSICHFVDASAGLNTTRAECEAACAEAYIGEEEQWGCRTGCREQLPHVQRREQSAEVKAPSLSVLDLVSSFCTDIVSSAHSFISSTWTFYLQADDGKVVVFQSQPHMEFPLPEAQMTQPEWPGPGDDAHSPQPHAGPQQKEEKSPPGKEPWGKAKPADTPQPEHDFLGCMAKRSGLPRWILAACLFLSIVVMLWLSCASLVTAPEQHIRTQPLSINGDRECLEDPRGLSAFPLPPVIAVTLCPTHGEDVGPLPLKVDLDKTIL", "length": 392, "header": "tr|A0A8V1AGE2-1|A0A8V1AGE2_CHICK Isoform 1 of Transmembrane protein 59 like OS=Gallus gallus OX=9031 GN=TMEM59L PE=3 SV=1 CANONICAL=A0A8V1AGE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2/entry#A0A8V1AGE2-1", "sequence": { "sequence": "GLREKRETLRSVSESSDAFIGARGDRKRRLLRRTKGDLGGAEKKLKRNGCEATGPRPAALPPSRPLLRRWRFWCPSLGSRHSSAELRSLKGDLAASVPALPHVGAAGRNSDRGTKEDAVLSACYRGCRLFSICHFVDASAGLNTTRAECEAACAEAYIGEEEQWGCRTGCREQLPHVQRREQSAEVKAPSLSVLDLVSSFCTDIVSSAHSFISSTWTFYLQADDGKVVVFQSQPHMEFPLPEAQMTQPEWPGPGDDAHSPQPHAGPQQKEEKSPPGKEPWGKAKPADTPQPEHDFLGCMAKRSGLPRWILAACLFLSIVVMLWLSCASLVTAPEQHIRTQPLSINGDRECLEDPRGLSAFPLPPVIAVTLCPTHGEDVGPLPLKVDLDKTIL", "length": 392, "header": "tr|A0A8V1AGE2-1|A0A8V1AGE2_CHICK Isoform 1 of Transmembrane protein 59 like OS=Gallus gallus OX=9031 GN=TMEM59L PE=3 SV=1 CANONICAL=A0A8V1AGE2-1" }, "locus": { "chromosome": "28", "start_pos": 4327500, "end_pos": 4318317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068904.1", "url": "https://www.ensembl.org/id/ENSGALT00010068904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042346.1", "url": "https://www.ensembl.org/id/ENSGALP00010042346.1" } ] } }, { "isoform_ac": "A0A8V1AKG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGE2/entry#A0A8V1AKG7-1", "sequence": { "sequence": "MAAPRPPALLALGLALTAATVTAAAGGDPFSAQLGDTGPCQRQCGRSVQPRAADAVLSACYRGCRLFSICHFVDASAGLNTTRAECEAACAEAYIGEEEQWGCRTGCREQLPHVQRREQSAEVKAPSLSVLDLVSSFCTDIVSSAHSFISSTWTFYLQADDGKVVVFQSQPHMEFPLPEAQMTQPEWPGPGDDAHSPQPHAGPQQKEEKSPPGKEPWGKAKPADTPQPEHDFLGCMAKRSGLPRWILAACLFLSIVVMLWLSCASLVTAPEQHIRTQPLSINGDRECLEDPRGLSAFPLPPVIAVTLCPTHGEDVGPLPLKVDLDKTIL", "length": 329, "header": "tr|A0A8V1AKG7-1|A0A8V1AKG7_CHICK Computationally mapped isoform of Transmembrane protein 59 like OS=Gallus gallus OX=9031 GN=TMEM59L PE=3 SV=1 CANONICAL=A0A8V1AGE2-1" }, "locus": { "chromosome": "28", "start_pos": 4322063, "end_pos": 4318317, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068901.1", "url": "https://www.ensembl.org/id/ENSGALT00010068901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042343.1", "url": "https://www.ensembl.org/id/ENSGALP00010042343.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420122", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420122", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S907-1", "protein_name": "Transmembrane protein 59 like", "gene_name": "TMEM59L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASVVLMPLLLLLLQPPPATPAPPVRDPFALQLGDTQSCQLRCRDRYPSPQPAQELEEDPTESPHVNAYDRAVLISACERGCRLFSICRFVARSSKPNATQAECEAACVEAYVKETEQQACSEGCWSQNPQLEPEPELEPEQKRKVLEAPSGALSLLDLFSTLCNDLVNSAQGFVSSTWTYYLQTDNGKVVVFQTQPVVESLGHEGTRLQRVEVTWRGSHPEALEVHVDPVGPLDKVRKAKIRVKTSSKAKIESDELQDNDFLSCMSRRSGLPRWILACCLFLSVLVMLWLSCSTLVTAPGQHLKFQPLTLEQHKGFMVEPDWPLYPPPSHAFADSPPPYKLKLDLTKL", "length": 349 }, "evidence": [ { "id": "A0A8V1AGE2", "url": "https://omabrowser.org/oma/group/A0A8V1AGE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0VCT2-1", "protein_name": "Transmembrane protein 59-like", "gene_name": "TMEM59L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSVALMPLLLLLLLQPPPATPAPPVRDPFALQLGDTQNCQLRCRDRYPKPQLAQEELGEDPIQSRRAKAYDRAVLTSACERGCRLFSICRFVARSSKPNATQAECEAACVEAYVKETEQQACSEGCWSQNPEPEPEPELEQKRKVLEAPSGALSLLDLFSTLCNDLVNSAQGFVSSTWTYYLQTDNGKVVVFQTQPVVESLGHEGARLQRVEVTWRGSHPEALEVHVDPVGPLDKVRKAKIRVKTSSKAKVESDELQDNDFLSCMSRRSGLPRWILACCLFLSVLVMLWLSCSTLVTAPGQHLKFQPLTLEQHKGYMVEPEWSLYPPPSHAYADSPPPYKLKLDLTKL", "length": 349 }, "evidence": [ { "id": "A0A8V1AGE2", "url": "https://omabrowser.org/oma/group/A0A8V1AGE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5HZE8-1", "protein_name": "Transmembrane protein 59-like", "gene_name": "Tmem59l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVALPLLLLLASPATPTPARDPFSPQLGDTQRCQQRCRQRHPGLPPAQPEPEGPSESPNNKAVLINACERGCRLFSICRFVARSSRPNATETECEAACTEAYVKAKEQQACSEGCWGQIPEPETQLEQKELALDPPSGSLSLRHLFTMLCSDLMSSAQDLISSTWTYSLQTDNRKTQPVVENFAFQGSRLQRVEVTWRGSHPKALEVHMDPMSPLEKVRRAKPHLKTSKAKVESEDQQESDFLSCMSRRSGLPRWVLFCCLFLSVLIILWLSCCTLVTTPGQHLKFQPLTAEQHKGLLVESNWPLYPPLPPAYEDSPPPYKLKLDLTTL", "length": 331 }, "evidence": [ { "id": "A0A8V1AGE2", "url": "https://omabrowser.org/oma/group/A0A8V1AGE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TNI2-1", "protein_name": "Transmembrane protein 59-like", "gene_name": "Tmem59l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVALPLLLLLASLVTPTPARDPFAPQLGDTQRCQQRCRQHHPGSPPAQPEPEGPSESPNNKAILISACERGCRLFSICRFVAKSSRPNATETECEAACTEAYVKAAEQRACSEGCWGQIPEPETQLEQKDLALDPPRGRLSLRYLFSMLCSDLMSSAQGFLSSSWTYSLQTDNRKVVVFQTQPVAENFAFQGSHLQRVEVTWRRSHPKALELHMDPVGPLDKVRKAKPRVKTSKAKVESEDQQESDFLSCMSRRSGLPRWVLFCCLFLSILIMLWLSCCTLVTTPGQHLKFQPLTAEQHKGLLVESDWPLYPPLPPPAYEDSTPPYKLKLDLTTL", "length": 337 }, "evidence": [ { "id": "A0A8V1AGE2", "url": "https://omabrowser.org/oma/group/A0A8V1AGE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UK28-1", "protein_name": "Transmembrane protein 59-like", "gene_name": "TMEM59L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGG9" }, { "id": "SM00249", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Zinc finger PHD-type", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 121, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGI1-1", "uniprot_ac": "A0A8V1AGI1", "uniprot_id": "A0A8V1AGI1_CHICK", "mass": { "chemical_mass": 67123.0, "monoisotopic_mass": 67123.0 }, "refseq": { "ac": "XP_040508390", "name": "DDB1- and CUL4-associated factor 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508390" }, "gene_names": [ { "name": "DCAF8", "type": "recommended", "evidence": [ { "id": "A0A8V1AGI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1" } ] }, { "name": "DCAF8", "type": "synonym", "evidence": [ { "id": "XP_040508390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508390" } ] } ], "protein_names": [ { "name": "DDB1 and CUL4 associated factor 8", "type": "synonym", "evidence": [ { "id": "A0A8V1AGI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1/entry#names_and_taxonomy" } ] }, { "name": "DDB1- and CUL4-associated factor 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040508390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508390" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508390" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCAF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "429253", "url": "https://www.ncbi.nlm.nih.gov/gene/429253", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MRMMNGD", "url": "https://omabrowser.org/oma/group/MRMMNGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGI1", "url": "https://www.orthodb.org/?gene=A0A8V1AGI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15574:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15574:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040508390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508390", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDKGNSMDGKTDIANGSLSSSPEEMSAEEGREISSGIEVEASDLSLSLTGDDVGPNRTSTESRDTDTESSGEEKDSDSMDDTGHYSINEETRTLDCSHSEEEEEEDEEEEQRSHRRAQRKRANHERDSSDDEQALEDWVSSETTALPQPRWQAIRALRDRELGSSPRFVYEACGARLFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRRPVLEFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCRSTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIFVNPANTYQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGSELLASYNDEDIYLFNSSHSDGAEYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIVQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAVTPTELTGLKEVIKKNKLERDEDSLHHTDMFDSHMLWFLMHHLRQRRHHRQRRREPGAPEADSDESPSSSDSSDEEEEGPDRVQCMPS", "length": 597, "header": "tr|A0A8V1AGI1-1|A0A8V1AGI1_CHICK Isoform 1 of DDB1 and CUL4 associated factor 8 OS=Gallus gallus OX=9031 GN=DCAF8 PE=1 SV=1 CANONICAL=A0A8V1AGI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1/entry#A0A8V1AGI1-1", "sequence": { "sequence": "MSDKGNSMDGKTDIANGSLSSSPEEMSAEEGREISSGIEVEASDLSLSLTGDDVGPNRTSTESRDTDTESSGEEKDSDSMDDTGHYSINEETRTLDCSHSEEEEEEDEEEEQRSHRRAQRKRANHERDSSDDEQALEDWVSSETTALPQPRWQAIRALRDRELGSSPRFVYEACGARLFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRRPVLEFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCRSTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIFVNPANTYQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGSELLASYNDEDIYLFNSSHSDGAEYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIVQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAVTPTELTGLKEVIKKNKLERDEDSLHHTDMFDSHMLWFLMHHLRQRRHHRQRRREPGAPEADSDESPSSSDSSDEEEEGPDRVQCMPS", "length": 597, "header": "tr|A0A8V1AGI1-1|A0A8V1AGI1_CHICK Isoform 1 of DDB1 and CUL4 associated factor 8 OS=Gallus gallus OX=9031 GN=DCAF8 PE=1 SV=1 CANONICAL=A0A8V1AGI1-1" }, "locus": { "chromosome": "25", "start_pos": 65414, "end_pos": 57109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068951.1", "url": "https://www.ensembl.org/id/ENSGALT00010068951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042393.1", "url": "https://www.ensembl.org/id/ENSGALP00010042393.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 511, "start_aa": "Thr", "end_pos": 511, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr511", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N3H0-1", "protein_name": "DDB1 and CUL4 associated factor 8", "gene_name": "DCAF8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSVNDESQVHDRSEEEEEEEHPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAETSTELTGLKDVIKKNKRERDEDSLHHTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS", "length": 591 }, "evidence": [ { "id": "A0A8V1AGI1", "url": "https://omabrowser.org/oma/group/A0A8V1AGI1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QF18-1", "protein_name": "DDB1- and CUL4-associated factor 8", "gene_name": "dcaf8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDTGGKSSIPNGGSDDPEPGEGRGEAETSDASAVAEAQASPESANLNSAAEGSAVGQDKLMADSEQKQGPAEEEDTDSMDGSGLYSLTEEGERESEGGGRGKDEGKRSARKRNRPSGGAAHHSSSSDDDDENEEDDDVEEEDEQAMEAWLGADLCDLSRPSWRAIPSLRAREIGRDSQQFVRKVCGARGLVQRLELQGRLERHTGCVNTLHFNPSGTRLASGSDDLRVVIWDWARRKAELEFDSGHKSNVFQAKFLPHSGDSTLAMCARDGQIRVAELSATQRCKNTKRVAQHKGAAHKLALEPDSPCSFLSAGEDAVVFGIDLRLDRPANKLVVVKEGEKKVGLYTIYVNPANTHHFAVGGRDQYVRIYDQRKINEHDNNGVLKKFCPSHLVSSESKTNITCLVYSHDGTELLASYNDEDIYLFDSSHSDGADYHRKYKGHRNNATVKGVNFYGPCSEFVVSGSDCGHIYLWDKNSARVVQFMEGDRGGVVNCLEPHPHLPGLATSGLDHDVKLWAPTAENPTTLKGLKEVMKKNKRERDEDNVRHGDQYDTQLLWFLMRHMRNRRPQRTRRGEGGEGDTDESWSSPESSDEEDGGPDHVQCMSS", "length": 607 }, "evidence": [ { "id": "A0A8V1AGI1", "url": "https://omabrowser.org/oma/group/A0A8V1AGI1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5TAQ9-1", "protein_name": "DDB1- and CUL4-associated factor 8", "gene_name": "DCAF8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYVKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHQTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS", "length": 597 }, "evidence": [ { "id": "A0A8V1AGI1", "url": "https://omabrowser.org/oma/group/A0A8V1AGI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U2M6-1", "protein_name": "DDB1- and CUL4-associated factor 8", "gene_name": "Dcaf8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKRPSTDGRRDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEEKDSDSMEDTGHYSINDENRVHGHSDEEEEEEQPRHRVQRKRASRDQDSSDDERALEDWVSSETTALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQFVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKDVIKKNKRERDEDSLHHTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS", "length": 591 }, "evidence": [ { "id": "A0A8V1AGI1", "url": "https://omabrowser.org/oma/group/A0A8V1AGI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N7N5-1", "protein_name": "DDB1- and CUL4-associated factor 8", "gene_name": "Dcaf8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKRPNTTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEEKDSDSMEDTGHYSINDESRGHGHSDEEDEEQPRHRGQRKRASRDQDSSDDERALEDWVSSETTALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGSDDLKVVVWDWVRRQPVLDFESGHKSNVFQAKFLPNSGDSTLAMCARDGQVRVAELSATQCCKNTKRVAQHKGASHKLALEPDSPCTFLSAGEDAVVFTIDLRQDRPASKLVVTKEKEKKVGLYTIYVNPANTHQFAVGGRDQYVRIYDQRKIDENENNGVLKKFCPHHLVNSESKANITCLVYSHDGTELLASYNDEDIYLFNSSHSDGAQYIKRYKGHRNNATVKGVNFYGPKSEFVVSGSDCGHIFLWEKSSCQIIQFMEGDKGGVVNCLEPHPHLPVLATSGLDHDVKIWAPTAEASTELTGLKEVIKKNKRERDEDSLHHTDLFDSHMLWFLMHHLRQRRHHRRWREPGVGATDADSDESPSSSDTSDEEEGPDRVQCMPS", "length": 591 }, "evidence": [ { "id": "A0A8V1AGI1", "url": "https://omabrowser.org/oma/group/A0A8V1AGI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M1E5-1", "protein_name": "Transducin/WD40 repeat-like superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARPRRRNTEIGDGFTEIFNREIGFSHPITISRRISASEGRVKKLDLYGKLNGHEGCVNAVEFNSTGDVLVSGSDDRQIMLWNWLSGSRKLSYPSGHCENVFQTKFIPFTDDRTIITSGADGQVRLGQILENGKVETKRLGRHHGRVYKLAVLPGDPNVFYSCGEDGFVQHFDIRSNSATMVLYSSPFTQGCRRHHSSSRIRLNSIAIDPRNSYYLAVGGSDEYARVYDTRRVQLAPVCRHVLPDAPVNTFCPRHLRETNSVHITGLAYSKAGELLVSYNDELIYLFEKNMGYGSSPVSVSPEKLQEMEEPQVYIGHRNAQTVKGVNFFGPNDEYVTSGSDCGHIFIWKKKGGKLVRAMVGDRRVVNQLESHPHIPLLASCGIEKSVKLWTPMSNDVLSLPEKIDKVMELNRVGREDQSRVTLTPDVIMHVLRLQRRQTSAFTERRYVSTDIGSDEGNDARFIASLVANDDESSDRECTVS", "length": 481 }, "evidence": [ { "id": "A0A8V1AGI1", "url": "https://omabrowser.org/oma/group/A0A8V1AGI1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 511 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGI7-1", "uniprot_ac": "A0A8V1AGI7", "uniprot_id": "A0A8V1AGI7_CHICK", "mass": { "chemical_mass": 18167.0, "monoisotopic_mass": 18167.0 }, "refseq": { "ac": "XP_001233931", "name": "bcl-2-like protein 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233931" }, "gene_names": [ { "name": "BCL2L15", "type": "recommended", "evidence": [ { "id": "A0A8V1AGI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7" } ] }, { "name": "BCL2L15", "type": "synonym", "evidence": [ { "id": "XP_001233931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233931" } ] } ], "protein_names": [ { "name": "BCL2 like 15", "type": "synonym", "evidence": [ { "id": "A0A8V1AGI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7/entry#names_and_taxonomy" } ] }, { "name": "bcl-2-like protein 15", "type": "synonym", "evidence": [ { "id": "XP_001233931", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233931" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233931.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233931" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCL2L15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7", "locus": { "chromosome": "26", "start_pos": 3801314, "end_pos": 3804063, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027395", "url": "https://www.ensembl.org/id/ENSGALG00010027395" } ] } } ], "crossref": [ { "id": "A0A8V1AGI7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "772088", "url": "https://www.ncbi.nlm.nih.gov/gene/772088", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772088", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772088", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVAISMT", "url": "https://omabrowser.org/oma/group/QVAISMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGI7", "url": "https://www.orthodb.org/?gene=A0A8V1AGI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36466:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36466:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001233931", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233931", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTFEEQTVCVVEALFDDLLNEDEADFRCLQTDSGVSVQSEEEPPSGFDPVIIANRLRQIGDQCNMDFERVSSQVLREVLMGKMEKFGAAVDSLCRRWSDQNPELVYERAFLSVSVKLMMYILKKGAANVNPGHLVKAINENTQVKNYIEARGGWEKLDN", "length": 160, "header": "tr|A0A8V1AGI7-1|A0A8V1AGI7_CHICK Isoform 1 of BCL2 like 15 OS=Gallus gallus OX=9031 GN=BCL2L15 PE=1 SV=1 CANONICAL=A0A8V1AGI7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7/entry#A0A8V1AGI7-1", "sequence": { "sequence": "MRTFEEQTVCVVEALFDDLLNEDEADFRCLQTDSGVSVQSEEEPPSGFDPVIIANRLRQIGDQCNMDFERVSSQVLREVLMGKMEKFGAAVDSLCRRWSDQNPELVYERAFLSVSVKLMMYILKKGAANVNPGHLVKAINENTQVKNYIEARGGWEKLDN", "length": 160, "header": "tr|A0A8V1AGI7-1|A0A8V1AGI7_CHICK Isoform 1 of BCL2 like 15 OS=Gallus gallus OX=9031 GN=BCL2L15 PE=1 SV=1 CANONICAL=A0A8V1AGI7-1" }, "locus": { "chromosome": "26", "start_pos": 3803948, "end_pos": 3801473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066422.1", "url": "https://www.ensembl.org/id/ENSGALT00010066422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040688.1", "url": "https://www.ensembl.org/id/ENSGALP00010040688.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772088", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772088", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ADT3-1", "protein_name": "Bcl-2-like protein 15", "gene_name": "BCL2L15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKPPRTFEEQTECIVDSLLTDFLGPSCQVANRSLRGVDETDSGEACSFDVAIIAGRLRMLGDKFNGELEASAKSIIAETIQGQAEAVFQDIVKSLSKAWCAQDSNLAYERALLGVSVKLLEYVAHLAPDVARQVAMPMRNMINGNSAIREYIQGQGGWENLES", "length": 163 }, "evidence": [ { "id": "A0A8V1AGI7", "url": "https://omabrowser.org/oma/group/A0A8V1AGI7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A1Q8-1", "protein_name": "Bcl-2-like protein 15", "gene_name": "Bcl2l15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKMKNPRTFEEQTECIMNTLLTDFLTPTFQAANRNLPDADEPCSGEDYSFDVAIVAGRLRMLGDKFNGELEASVNNIIAETIRGQAGTVLKDTVQSLSKTWCTQNPTLAFETAFLAVSVKLLEYVARKAPEMASQVAACMTGMINGDTTIRQFIQDLGGWGNLEG", "length": 166 }, "evidence": [ { "id": "A0A8V1AGI7", "url": "https://omabrowser.org/oma/group/A0A8V1AGI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08ED0-1", "protein_name": "Bcl-2-like protein 15", "gene_name": "Bcl2l15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKMKNPRTFEEQTECIVNSLLKDFRTPLSHAANRNLSGADEPCSGEDYSFDVAIIVGRLRILGDQFNGELEASANNIIAVTIGGQAGSTVLNDTVQSLSRTWCTQDPTLVFERAFLAVSVKLLEYVVRKAPNVARQVANYVTGMINGNTAIREFIQGQGGWENLES", "length": 167 }, "evidence": [ { "id": "A0A8V1AGI7", "url": "https://omabrowser.org/oma/group/A0A8V1AGI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0II48-1", "protein_name": "Bcl-2-like protein 15", "gene_name": "BCL2L15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSPRTFEEQTECIVNALLTDFLGPAWEVGNRTLQCEDESDSGEVSSFDVAIIAGRLRMLGDKFNGELEASAKNVIAETIRGQAGIVLQNTVKSLSNAWCAQDSSLAYERAFLAVSVKLLEHVARMAPEVARQVVRPITNMINGNTAIREYIQGQGGWENLEG", "length": 162 }, "evidence": [ { "id": "A0A8V1AGI7", "url": "https://omabrowser.org/oma/group/A0A8V1AGI7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5TBC7-1", "protein_name": "Bcl-2-like protein 15", "gene_name": "BCL2L15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSSQTFEEQTECIVNTLLMDFLSPTLQVASRNLCCVDEVDSGEPCSFDVAIIAGRLRMLGDQFNGELEASAKNVIAETIKGQTGAILQDTVESLSKTWCAQDSSLAYERAFLAVSVKLLEYMAHIAPEVVGQVAIPMTGMINGNQAIREFIQGQGGWENLES", "length": 163 }, "evidence": [ { "id": "A0A8V1AGI7", "url": "https://omabrowser.org/oma/group/A0A8V1AGI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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"tr|A0A8V1AGI9-1|A0A8V1AGI9_CHICK Isoform 1 of BTB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107055327 PE=4 SV=1 CANONICAL=A0A8V1AGI9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PN64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGI9/entry#A0A1D5PN64-1", "sequence": { "sequence": "MGRLGRRRASLSASLKPGARRGCRTPEEEEVHIPFAQDSLVKQWSSMQNVADWSQEESKVPVRRNKYFLNINVGGKLFHIACKVVARYPVTRLGKLATCTDPTKKLKLCDDYSVQKNEYFFDRDPSIFHYIFHFYCSGVLWIMDEMCPSNFVEEIEYWGIHLKHSQRCCRILFEEKQDELSEYLKIQKELEAELEPVDSAEQFEGKCLGKFRRAIWDLIENPYSSVPAKIIAVMSSFFVLISIVGMTLSTVEEMKHKTGKKWMEQMEMICAIFFTSEYLMRLISSSSLKNFLRAALNAIDLVAILPFYIQILFENLDEGETLYHEELHKVENVSKLGKVLKLIKLMRIFRILKLARHSTGLRAFGFTMRQCYQQVCCLFLFIAMGVFTFSALMHSVEHDVPGTNFTSIPYAWWWAAVSLSTVGYGDTVPDTVLGRIVAFGCISFGIILNGMPISILYNKFSDYYAKLKAHENESSLSLKLSRRLRLKERVLRKLSECCRPDPHCQH", "length": 506, "header": "tr|A0A1D5PN64-1|A0A1D5PN64_CHICK Computationally mapped isoform of BTB domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107055327 PE=4 SV=1 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGJ0-1", "uniprot_ac": "A0A8V1AGJ0", "uniprot_id": "A0A8V1AGJ0_CHICK", "mass": { "chemical_mass": 29120.0, "monoisotopic_mass": 29120.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AGJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ0", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR33426", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33426", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33426:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33426:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVAHEAGNSFGGSHKLQAPLQLVFPVNALVGAEVRTSSKALPTLRALIGCLSCVDVLVVNEVRTSFEALLTLRALKWSLSCVDAVVDNEIRTACEALSTLVALVGSLSCVGALVVGEMGISFEGLPTLRAFVGSLSCVDVLVVDEFRIAFEALPTLMAFVGSLSWVDVLVADEGRNAPEALLTLRALVGSLSCVDKLVADKVRIAFETLPTLSALVGSLSCVDALVAVEAKIVFEALPTLRTLKWSLSCVHALVVGEGGSPFEALCTIRALVQCLL", "length": 277, "header": "tr|A0A8V1AGJ0-1|A0A8V1AGJ0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ0/entry#A0A8V1AGJ0-1", "sequence": { "sequence": "MRVAHEAGNSFGGSHKLQAPLQLVFPVNALVGAEVRTSSKALPTLRALIGCLSCVDVLVVNEVRTSFEALLTLRALKWSLSCVDAVVDNEIRTACEALSTLVALVGSLSCVGALVVGEMGISFEGLPTLRAFVGSLSCVDVLVVDEFRIAFEALPTLMAFVGSLSWVDVLVADEGRNAPEALLTLRALVGSLSCVDKLVADKVRIAFETLPTLSALVGSLSCVDALVAVEAKIVFEALPTLRTLKWSLSCVHALVVGEGGSPFEALCTIRALVQCLL", "length": 277, "header": "tr|A0A8V1AGJ0-1|A0A8V1AGJ0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGJ0-1" }, "locus": { "chromosome": "18", "start_pos": 665597, "end_pos": 664515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070541.1", "url": "https://www.ensembl.org/id/ENSGALT00010070541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043232.1", "url": "https://www.ensembl.org/id/ENSGALP00010043232.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGJ3-1", "uniprot_ac": "A0A8V1AGJ3", "uniprot_id": "A0A8V1AGJ3_CHICK", "mass": { "chemical_mass": 58042.0, "monoisotopic_mass": 58042.0 }, "refseq": { "ac": "XP_003642746", "name": "DNA-binding protein RFX5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642746" }, "gene_names": [ { "name": "RFX5", "type": "recommended", "evidence": [ { "id": "A0A8V1AGJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3" } ] }, { "name": "RFX5", "type": "synonym", "evidence": [ { "id": "XP_003642746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642746" } ] } ], "protein_names": [ { "name": "DNA-binding protein RFX5", "type": "synonym", "evidence": [ { "id": "XP_003642746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642746" } ] }, { "name": "Regulatory factor X5", "type": "synonym", "evidence": [ { "id": "A0A8V1AGJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003642746.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642746" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RFX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3", "locus": { "chromosome": "25", "start_pos": 2693379, "end_pos": 2697220, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027397", "url": "https://www.ensembl.org/id/ENSGALG00010027397" } ] } } ], "crossref": [ { "id": "A0A8V1AGJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857912", "url": "https://www.ncbi.nlm.nih.gov/gene/100857912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857912", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEHIVNP", "url": "https://omabrowser.org/oma/group/NEHIVNP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A481", "url": "https://www.orthodb.org/?gene=A0A8V1A481", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGJ3", "url": "https://www.orthodb.org/?gene=A0A8V1AGJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642746", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A481", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A481", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A481-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A481-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADEELSPQAAKKGTLSPGGSRSGVAEPGTLLQKLRGNISKAVQNKVDAILQDVQKFSDSDKLYLYLQLPSGPSMGDRSSSLDLSSLSTAEYMHACNWIRNHLEEHADTCLPKQDVYDAYRQYCDNLCCRPLSAANFGKIIREIFPNIKARRLGGRGQSKYCYSGIRRKTVVSLPPLPSLDLKVTETQHTELTDLVQSYTSEVMEAACALTCDWAEKILKRSFNNIVEVAQFLIQQHIISSRSARADLVMAMVVSESTEKAHRDGRSPPLAKRNGLEASEGGERSLAQTKKDSVPKATIPPRPDKKKPPEPPRPPSSPQVNALMARLPLLLPRVPPGPTAVCSSPPVLAPKLTAAPLGGTMKVAVPLPPGLNVLLPGVAVPAADSPRGAAPDGPPGSAQRPVATKRSPEVAHEAGAKRRRGRPRKRTEEEEGGVGSPGRTGDAAEGTDLGAERCDSAHGGDSGHRGGSARGGDSGHGGDGAHGGDITDGAAVVSPTQVSVIQDSRGLQEEEALSAAPGGSGVTGGGSADTALRGDGHGAGMEPSAPHGPVFPGGT", "length": 555, "header": "tr|A0A8V1AGJ3-1|A0A8V1AGJ3_CHICK Isoform 1 of Regulatory factor X5 OS=Gallus gallus OX=9031 GN=RFX5 PE=1 SV=1 CANONICAL=A0A8V1AGJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A481-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3/entry#A0A8V1A481-1", "sequence": { "sequence": "MLALFWILHLSLSPVPPPLLTDPSPIARCPEVLRQRQALPLPPAAVRAKHGGQEVGAGGPSLHAIIPIHSLHTIIPSSSLDLSSLSTAEYMHACNWIRNHLEEHADTCLPKQDVYDAYRQYCDNLCCRPLSAANFGKIIREIFPNIKARRLGGRGQSKYCYSGIRRKTVVSLPPLPSLDLKVTETHTELTDLVQSYTSEVMEAACALTCDWAEKILKRSFNNIVEVAQFLIQQHIISSRSARADLVMAMVVSESTEKAHRDGRSPPLAKRNGLEASEGGERSLAQTKKDSVPKATIPPRPDKKKPPEPPRPPSSPQVNALMARLPLLLPRVPPGPTAVCSSPPVLAPKLTAAPLGGTMKVAVPLPPGLNVLLPGVAVPAADSPRGAAPDGPPGSAQRPVATKRSPEVAHEAGAKRRRGRPRKRTEEEEGGVGSPGRTGDAAEGTDLGAERCDSAHGGDSGHRGGSARGGDSGHGGDGAHGGDITDGAAVVSPTQVSVIQDSRGLQEEEALSAAPGGSGVTGGGSADTALRGDGHGAGMEPSAPHGPVFPGGT", "length": 552, "header": "tr|A0A8V1A481-1|A0A8V1A481_CHICK Computationally mapped isoform of Regulatory factor X5 OS=Gallus gallus OX=9031 GN=RFX5 PE=1 SV=1 CANONICAL=A0A8V1AGJ3-1" }, "locus": { "chromosome": "25", "start_pos": 2695971, "end_pos": 2693457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066426.1", "url": "https://www.ensembl.org/id/ENSGALT00010066426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040692.1", "url": "https://www.ensembl.org/id/ENSGALP00010040692.1" } ] } }, { "isoform_ac": "A0A8V1AGJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3/entry#A0A8V1AGJ3-1", "sequence": { "sequence": "MADEELSPQAAKKGTLSPGGSRSGVAEPGTLLQKLRGNISKAVQNKVDAILQDVQKFSDSDKLYLYLQLPSGPSMGDRSSSLDLSSLSTAEYMHACNWIRNHLEEHADTCLPKQDVYDAYRQYCDNLCCRPLSAANFGKIIREIFPNIKARRLGGRGQSKYCYSGIRRKTVVSLPPLPSLDLKVTETQHTELTDLVQSYTSEVMEAACALTCDWAEKILKRSFNNIVEVAQFLIQQHIISSRSARADLVMAMVVSESTEKAHRDGRSPPLAKRNGLEASEGGERSLAQTKKDSVPKATIPPRPDKKKPPEPPRPPSSPQVNALMARLPLLLPRVPPGPTAVCSSPPVLAPKLTAAPLGGTMKVAVPLPPGLNVLLPGVAVPAADSPRGAAPDGPPGSAQRPVATKRSPEVAHEAGAKRRRGRPRKRTEEEEGGVGSPGRTGDAAEGTDLGAERCDSAHGGDSGHRGGSARGGDSGHGGDGAHGGDITDGAAVVSPTQVSVIQDSRGLQEEEALSAAPGGSGVTGGGSADTALRGDGHGAGMEPSAPHGPVFPGGT", "length": 555, "header": "tr|A0A8V1AGJ3-1|A0A8V1AGJ3_CHICK Isoform 1 of Regulatory factor X5 OS=Gallus gallus OX=9031 GN=RFX5 PE=1 SV=1 CANONICAL=A0A8V1AGJ3-1" }, "locus": { "chromosome": "25", "start_pos": 2696632, "end_pos": 2693457, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066427.1", "url": "https://www.ensembl.org/id/ENSGALT00010066427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040693.1", "url": "https://www.ensembl.org/id/ENSGALP00010040693.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 339, "start_aa": "Thr", "end_pos": 339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr339", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857912", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857912", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ3" } ], "pmid": "" } ] }, { "name": "Biological 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{ "uniprot_canonical_ac": "A0A8V1AGJ7-1", "uniprot_ac": "A0A8V1AGJ7", "uniprot_id": "A0A8V1AGJ7_CHICK", "mass": { "chemical_mass": 57205.0, "monoisotopic_mass": 57205.0 }, "refseq": { "ac": "XP_004945813", "name": "NADPH oxidase activator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945813" }, "gene_names": [ { "name": "NOXA1", "type": "recommended", "evidence": [ { "id": "A0A8V1AGJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ] }, { "name": "NOXA1", "type": "synonym", "evidence": [ { "id": "XP_004945813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945813" } ] } ], "protein_names": [ { "name": "NADPH oxidase activator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945813" } ] }, { "name": "NADPH oxidase activator 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AGJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945813.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945813" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOXA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7", "locus": { "chromosome": "17", "start_pos": 1592584, "end_pos": 1578219, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028484", "url": "https://www.ensembl.org/id/ENSGALG00010028484" } ] } } ], "crossref": [ { "id": "A0A8V1AGJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417282", "url": "https://www.ncbi.nlm.nih.gov/gene/417282", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417282", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417282", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VLYRMVA", "url": "https://omabrowser.org/oma/group/VLYRMVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGJ7", "url": "https://www.orthodb.org/?gene=A0A8V1AGJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15175", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15175", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15175:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15175:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5668599", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945813", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYRELLRRWHQAALAADGGDWDAALETLCGIEEPPARICFNVGCVHLRAGRLRDALRAFDETVMKDNSLAVGYFQRGFVCLQLEMYEEALSDYHMAFSHLRKNPFIDYKQLGLRHILYAWEVLYSTAATQCRLQQWQEARDTLEKAVVWRPEGRSATLALALERVQNHQFLEPMQVPPGEFFRPRKKEVEQLDSKDFLGKPKVISSIIPNDEYIGFEPLRPQKQGFYEPSADSVRDRESGYYRVLSHYYPEGTEKLAVKASSLVFVLARGANGWATAIHDGQKLHIPTSLLEPASKMDKWKIGDGIPLPPAQVPPSRLHVKQTPDSPGEENVSANDSGSQVDFESPLTHREASSSTDRPAVLRVRCECTVVVRAGEVPSVPALRALLRERFGQQAERGRLSYRHLDGKELGAVSGEEDLEKMWQQLTDGRITLCCQDSDSHSGRPILYRMLAQHSYSAQGPGDLEFSKGDVLDILSEVNEDWLEGHCNGKTGIFPKCFATQTSCAAFP", "length": 509, "header": "tr|A0A8V1AGJ7-1|A0A8V1AGJ7_CHICK Isoform 1 of NADPH oxidase activator 1 OS=Gallus gallus OX=9031 GN=NOXA1 PE=1 SV=1 CANONICAL=A0A8V1AGJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7/entry#A0A8V1AGJ7-1", "sequence": { "sequence": "MAYRELLRRWHQAALAADGGDWDAALETLCGIEEPPARICFNVGCVHLRAGRLRDALRAFDETVMKDNSLAVGYFQRGFVCLQLEMYEEALSDYHMAFSHLRKNPFIDYKQLGLRHILYAWEVLYSTAATQCRLQQWQEARDTLEKAVVWRPEGRSATLALALERVQNHQFLEPMQVPPGEFFRPRKKEVEQLDSKDFLGKPKVISSIIPNDEYIGFEPLRPQKQGFYEPSADSVRDRESGYYRVLSHYYPEGTEKLAVKASSLVFVLARGANGWATAIHDGQKLHIPTSLLEPASKMDKWKIGDGIPLPPAQVPPSRLHVKQTPDSPGEENVSANDSGSQVDFESPLTHREASSSTDRPAVLRVRCECTVVVRAGEVPSVPALRALLRERFGQQAERGRLSYRHLDGKELGAVSGEEDLEKMWQQLTDGRITLCCQDSDSHSGRPILYRMLAQHSYSAQGPGDLEFSKGDVLDILSEVNEDWLEGHCNGKTGIFPKCFATQTSCAAFP", "length": 509, "header": "tr|A0A8V1AGJ7-1|A0A8V1AGJ7_CHICK Isoform 1 of NADPH oxidase activator 1 OS=Gallus gallus OX=9031 GN=NOXA1 PE=1 SV=1 CANONICAL=A0A8V1AGJ7-1" }, "locus": { "chromosome": "17", "start_pos": 1591590, "end_pos": 1578327, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068971.1", "url": "https://www.ensembl.org/id/ENSGALT00010068971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042413.1", "url": "https://www.ensembl.org/id/ENSGALP00010042413.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417282", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417282", "resource": "KEGG Pathway" }, { "id": "R-GGA-5668599", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5668599", "resource": "Reactome", "description": "RHO GTPases Activate NADPH Oxidases" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AZB9-1", "protein_name": "NADPH oxidase activator 1", "gene_name": "NOXA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSLGDLVRDWHRGAQAVARGDWGCALRLFSGIPEPPARMSFNVGCVHLLAGDPEAALQAFDQAVTRDACLAVGFFQRGVANFQLERFQEALSDFQLALAQLKDNATIDYTQLGLRFKLQAWEVLFNVAAVQCQLGLWAEATRSLEEAISKGPEGARGDLDIALGQVQEQAPLQPRQVPRGEVFRPRQRHLEHLEPVDFLGKAKVVASAVPDDQHQGIRPQQPQAGNEHGEARPRAAARAGTPCGPRKPPDVEMEMGCGQAGQAEHGRPLTSAKQSPHVERVDQQAPPGPTCSPPSAGLLAAEGPDPGSSEDPAGAGGVATGQPAALVTVLVQCAFTLALRAPRGADLSSLRALISQALPPQAQCGQLSYRDPSDGSCWVPLTGEEALQTAWREAATGPAGLRLQCRGVGGRPVLYQVVAQHSYSAQGPADLALQPGDTVDVLCQVDQAWLEGHCDGRIGIFPKCFVVPADRRV", "length": 474 }, "evidence": [ { "id": "A0A8V1AGJ7", "url": "https://omabrowser.org/oma/group/A0A8V1AGJ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A7E3N7-1", "protein_name": "NADPH oxidase activator 1", "gene_name": "Noxa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSLGDQIRDWHRGVLAVAREDWDSALCFFSDVREPLAKMYFNMGCVHLMAGDPEAALRAFDQAVTKDTCMAVGFLQRGVANFQLQRLQEAVSDFQLALAQLRGNAAIDYTQLGLDFKLQAWEVLYNMASVQCQAGLWTKAANTLVEAISKRPEGAQDTLEAAMDKVQKQVPLQLRQVPKGEVFQPPRRYLKHLEPMDFLGKAKVVASVIPDDHNSDIQPQQSSQVEQAGLQSSSPVCKRVLSTRGGHMSPGLWDSLLATGGPVPGPSEDSSSAEGTATKDPESLVTVTVQCHFTVPLKVPRGTDLSSFRTLLSQALLQQTQKGQFSYKARGEDRAWVPISTEDSLQSVWRNVPVSPRGLQLQCRGAWGRPVLYQVVAQYDYRAQRPEDLDFRQGDTVDVLCEVDEAWLEGHRDGRVGIFPKCFVVPAATCVEALPVPEPQPGEQH", "length": 446 }, "evidence": [ { "id": "A0A8V1AGJ7", "url": "https://omabrowser.org/oma/group/A0A8V1AGJ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I5X9-1", "protein_name": "NADPH oxidase activator 1", "gene_name": "Noxa1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSLADQVRDWHQGVLAVARKDWDRALCLFSDVREPPAKIYFNMGCVHLMAGDPEAALRAFDQAVTKDTCMAVGFFQRGVANFQLERFQEAVSDFQLTLAQLRGNAAIDYTQLGLHFKLQAWEVLYNMASAECQAGLWAKAADTLVEATSKWPEGAQGILDTALDQVQKQVPLQLRQVPKGEVFQPPRQYLQHLKPMDFLGKAKVVASVIPDNHNTDGWPQQRPRVEQVGHQSPPSTGGPMSCDLLESGRPAPDPSGDSSGAGGATAKDPESLVTVTVQCHFTVPVKAPRDTDLSSLRTLLAQALLHQAHMGQLSYQAPGEEKFWVHISTEESLQSVWRNVAMGPRGLHLQCRGAWGRPVLYQVIAQHDYSAQRPEDLDFHRGDTVDVLCEVDEAWLEGHRDGCIGIFPKCFVVPAGAYVEALPKPGDQH", "length": 430 }, "evidence": [ { "id": "A0A8V1AGJ7", "url": "https://omabrowser.org/oma/group/A0A8V1AGJ7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q86UR1-1", "protein_name": "NADPH oxidase activator 1", "gene_name": "NOXA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLGDLVRAWHLGAQAVDRGDWARALHLFSGVPAPPARLCFNAGCVHLLAGDPEAALRAFDQAVTKDTCMAVGFFQRGVANFQLARFQEALSDFWLALEQLRGHAAIDYTQLGLRFKLQAWEVLHNVASAQCQLGLWTEAASSLREAMSKWPEGSLNGLDSALDQVQRRGSLPPRQVPRGEVFRPHRWHLKHLEPVDFLGKAKVVASAIPDDQGWGVRPQQPQGPGANHDARSLIMDSPRAGTHQGPLDAETEVGADRCTSTAYQEQRPQVEQVGKQAPLSPGLPAMGGPGPGPCEDPAGAGGAGAGGSEPLVTVTVQCAFTVALRARRGADLSSLRALLGQALPHQAQLGQLSYLAPGEDGHWVPIPEEESLQRAWQDAAACPRGLQLQCRGAGGRPVLYQVVAQHSYSAQGPEDLGFRQGDTVDVLCEVDQAWLEGHCDGRIGIFPKCFVVPAGPRMSGAPGRLPRSQQGDQP", "length": 476 }, "evidence": [ { "id": "A0A8V1AGJ7", "url": "https://omabrowser.org/oma/group/A0A8V1AGJ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CJ00-1", "protein_name": "NADPH oxidase activator 1", "gene_name": "Noxa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLGDQIRDWHRGVLAVAREDWDSALCFFSDVREPLARMYFNRGCVHLMAGDPEAALRAFDQAVTKDTCMAVGFLQRGVANFQLQRFQEAVSDFQLALAQLRDNAVIDYTQLGLNFKLQAWEVLYNMASAQCQAGLWTKAANTLVEAISKWPEGAQDILDIAMDKVQKQVPLQLQQVPKGEVFQPPRRYLKHLEPMDFLGKAKVVASVIPDDHNAQPQQRSQAEHAGHQPSSSMCKRVLSTTGGHTSPGLYDSLLASRRPGPGPSEVSSGSEGAATKDPESLVTVTVQCHFTVPLKVPRGTGLSSFQTLLAQALLHQTQTGQLSYKAPGEERSWIPISTEESLQSIWRNVPVGPGGLQLQCQGVWGRPVLYQVVAQYNYRAQRPEDLDFHQGDTVDVLCEVDEAWLEGHRDGCVGIFPKCFVVPAGAYVEAMLVLGPQPGDQN", "length": 444 }, "evidence": [ { "id": "A0A8V1AGJ7", "url": "https://omabrowser.org/oma/group/A0A8V1AGJ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "NADPH oxidase complex", "id": "GO:0043020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" }, { "name": "superoxide-generating NADPH oxidase activator activity", "id": "GO:0016176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016176", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" }, { "name": "regulation of hydrogen peroxide metabolic process", "id": "GO:0010310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" }, { "name": "regulation of respiratory burst", "id": "GO:0060263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGJ7" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 446, "end_pos": 505, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 332, "end_pos": 334 }, { "start_pos": 336, "end_pos": 338 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGK1-1", "uniprot_ac": "A0A8V1AGK1", "uniprot_id": "A0A8V1AGK1_CHICK", "mass": { "chemical_mass": 102017.0, "monoisotopic_mass": 102017.0 }, "refseq": {}, "gene_names": [ { "name": "LOC101749378", "type": "recommended", "evidence": [ { "id": "A0A8V1AGK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1" } ] } ], "protein_names": [ { "name": "Rho GTPase activating protein 30", "type": "synonym", "evidence": [ { "id": "A0A8V1AGK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101749378", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGK1", "url": "https://www.orthodb.org/?gene=A0A8V1AGK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLALKARQKAKRKGGGAKERVFGCDLLEHLQQSGKDVPQVLRSCTEFVEQHGVVDGIYRLSGVSSNIQRLRQEFDGERSPDLQKDVYLQDIHCVSSLCKAYFRELPNPLLTYRLYDRFADAVATQMEEVRLVKIKEVLKELPPPHYRTLEFLMRHLLRMASYSHTTNMHARNLAIVWAPNLLRSRDIEATGFNGTAAFMEVRVQSIVVEFILTHVEQLFGDAPLCGGEAARCSRLFPGDGSGPYNVPAALSQGDGPPPIRPYHTIIELSDHRRKGSLKAKKWKSIFHLGRSDAKRKLGKAEEKGGSTAPPAPFDTCSSLPPTGTFPALEESPEEKLTATEEPRGPESESESSTKSEPTTPRPGRMAVVGARSRAEKCAGVHISGPFSVTVPLHITSNLSRLTRGQQCPALAQHGAIGSPPPTRRPTKEPKPPQTNTGEMRGHGAHSVGRTGGVIASPRCAFIEEDARLSLELRDSFAFLDCQDAWLEHGDGDAAARAALGHGGLGDSDGYPAIEEGMESGFMNVSWSSPVEQPASYLSIEECMDEEMFYMAPSGSDTEEPTGDTDSDDMFLSAHDELSPLAADPETPTASTALGECGAELRDGFPPPEPRPAEEVAPGDGGHLEDPSGDTAEVGGQIAVKEERGGGDREGNDGSSRTELGLEDKDGGTGAMLAPGGKEEKDGAPKQSGEGDPQPLEVPPSPEGPLQEPTEPPLPQESVPTVPPSRVDVPEGPPTPVAVQGAPPTPMVVPEVPPTPMVVQGVLPTPAAVPERAQIPRQRPSPPPLPGAAPDPSPTPSSPQRPRQPPPGAVLRRDGSAPVRLASRPVRVQQARSVPVVPPKPQFAIVPPTLQPHTPPAEGRRANWQHGGSVSFDAAMMDAAPERPSVRRIQTYGGGEMPSAPPNAPPQPLPFQKAPMRPRLLRPHSCMAAPQGRSLGQDGGTSPKQRAEGTAGEH", "length": 954, "header": "tr|A0A8V1AGK1-1|A0A8V1AGK1_CHICK Isoform 1 of Rho GTPase activating protein 30 OS=Gallus gallus OX=9031 GN=LOC101749378 PE=4 SV=1 CANONICAL=A0A8V1AGK1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1/entry#A0A8V1AGK1-1", "sequence": { "sequence": "MSLALKARQKAKRKGGGAKERVFGCDLLEHLQQSGKDVPQVLRSCTEFVEQHGVVDGIYRLSGVSSNIQRLRQEFDGERSPDLQKDVYLQDIHCVSSLCKAYFRELPNPLLTYRLYDRFADAVATQMEEVRLVKIKEVLKELPPPHYRTLEFLMRHLLRMASYSHTTNMHARNLAIVWAPNLLRSRDIEATGFNGTAAFMEVRVQSIVVEFILTHVEQLFGDAPLCGGEAARCSRLFPGDGSGPYNVPAALSQGDGPPPIRPYHTIIELSDHRRKGSLKAKKWKSIFHLGRSDAKRKLGKAEEKGGSTAPPAPFDTCSSLPPTGTFPALEESPEEKLTATEEPRGPESESESSTKSEPTTPRPGRMAVVGARSRAEKCAGVHISGPFSVTVPLHITSNLSRLTRGQQCPALAQHGAIGSPPPTRRPTKEPKPPQTNTGEMRGHGAHSVGRTGGVIASPRCAFIEEDARLSLELRDSFAFLDCQDAWLEHGDGDAAARAALGHGGLGDSDGYPAIEEGMESGFMNVSWSSPVEQPASYLSIEECMDEEMFYMAPSGSDTEEPTGDTDSDDMFLSAHDELSPLAADPETPTASTALGECGAELRDGFPPPEPRPAEEVAPGDGGHLEDPSGDTAEVGGQIAVKEERGGGDREGNDGSSRTELGLEDKDGGTGAMLAPGGKEEKDGAPKQSGEGDPQPLEVPPSPEGPLQEPTEPPLPQESVPTVPPSRVDVPEGPPTPVAVQGAPPTPMVVPEVPPTPMVVQGVLPTPAAVPERAQIPRQRPSPPPLPGAAPDPSPTPSSPQRPRQPPPGAVLRRDGSAPVRLASRPVRVQQARSVPVVPPKPQFAIVPPTLQPHTPPAEGRRANWQHGGSVSFDAAMMDAAPERPSVRRIQTYGGGEMPSAPPNAPPQPLPFQKAPMRPRLLRPHSCMAAPQGRSLGQDGGTSPKQRAEGTAGEH", "length": 954, "header": "tr|A0A8V1AGK1-1|A0A8V1AGK1_CHICK Isoform 1 of Rho GTPase activating protein 30 OS=Gallus gallus OX=9031 GN=LOC101749378 PE=4 SV=1 CANONICAL=A0A8V1AGK1-1" }, "locus": { "chromosome": "25", "start_pos": 111366, "end_pos": 99681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068976.1", "url": "https://www.ensembl.org/id/ENSGALT00010068976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042418.1", "url": "https://www.ensembl.org/id/ENSGALP00010042418.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 735, "start_aa": "Thr", "end_pos": 735, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr735", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 745, "start_aa": "Thr", "end_pos": 745, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr745", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 755, "start_aa": "Thr", "end_pos": 755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr755", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 765, "start_aa": "Thr", "end_pos": 765, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr765", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 795, "start_aa": "Thr", "end_pos": 795, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr795", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK1" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 220, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 735, 745, 755, 765, 795 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 524, "end_pos": 526 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGK4-1", "uniprot_ac": "A0A8V1AGK4", "uniprot_id": "A0A8V1AGK4_CHICK", "mass": { "chemical_mass": 72054.0, "monoisotopic_mass": 72054.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "A-kinase anchor protein 2 C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR18839", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18839", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18839:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18839:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15304", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15304", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A963", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A963", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A963-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A963-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRVTRHMVFQFPHTRDHSDAYQGDASMDGDDDIFDYSSQKENGKDVWNPSPDRESQLEVVRSGNLYDLRAYRGERKPSKLYEDDEPDPYRLQPPNISPQKAKELEDKRKEVIRGQVVRKSSTMAEKWTFAIYFDKPSPGRAVTPVDPESIDREQINFSAARQQFLMLEKNSPGVLFSPGYATSPRPEVTVKTSRQEWHSPPVGSSSDTVTRAERGHGDTTGPTQGGMDQSVYTVYSVQHQASGKEEGYAHGKGNTNVSQPKGRALGLARASSRDDLDSGLGEMYSAGYRSNGSDVPNGLWDVKDGGGSAEGSGETPIEREIRRALEREESLWKERGMQRLTSSSELVEIQTKPLLSLHTAPAQGRKGKDKGRASFNVQREIEKETKREEDLRRQGRLPGLYDRGTPQELGELRRVFEEDSTGGRLPGPTPSPVLRREHFALSFWQPRISVSDGMGTRSAAGRELSPDGEHGRDEQYTLRTWRPQRSALIEEEIRSDLQREEELQEQRRRRLMDGGDGTSRESSRSRHSSGKGRADPAPRVRGCPPGDRSAPGQGGTSGCGDPHAASLSLSLSAAASGASGSYSVSGSPVSTPQKPGVLGLVTSFTPLRLSCSESSGPDSVRCSPSEERRRRTKEEGKVRRGGGGVEGEMGVPW", "length": 654, "header": "tr|A0A8V1AGK4-1|A0A8V1AGK4_CHICK Isoform 1 of A-kinase anchor protein 2 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A963-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4/entry#A0A8V1A963-1", "sequence": { "sequence": "MDRVTRHMVFQFPHTRDHSDRGKDVWNPSPDRESQLEVVRSGNLYDLRAYRGERKPSKLYEDDEPDPYRLQPPNISPQKAKELEDKRKEVIRGQVVRKSSTMAEKWSSMDDHGVPGAFAIYFDKPSPGRAVTPVDPESIDREQINFSAARQQFLMLEKNSPGVLFSPGYATSPRPEVTVKTSRQDAGYRSNGSDVPNGLWDVKDGGGSAEGSGETPIEREIRRALEREESLWKERGMQRLTSSSELVEIQTKPLLSLHTAPAQGRKGKDKGRASFNVQREIEKETKREEDLRRQGRLPGLYDRGTPQELGELRRVFEQEEQQPAREDSTGGRLPGPTPSPVLRREHFALSFWQPRISVSDGMGTRSAAGRELSPDGEHGRDEQYTLRTWRPQRSALIEEEIRSDLQREEELQEQRRRRLMDGGDGTSRESSRSRHSSGKGRADPAPRVRGCPPGDRSAPGQGGTSGCGDPHAASLSLSLSAAASGASGSYSVSGSPVSTPQKPGVLGLVTSFTPLRLSCSESSGPDSVRCSPSEERRRRTKEEGKVRRGGGGVEGEMGVPW", "length": 561, "header": "tr|A0A8V1A963-1|A0A8V1A963_CHICK Computationally mapped isoform of A-kinase anchor protein 2 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGK4-1" }, "locus": { "chromosome": "28", "start_pos": 3206275, "end_pos": 3204016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066449.1", "url": "https://www.ensembl.org/id/ENSGALT00010066449.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040715.1", "url": "https://www.ensembl.org/id/ENSGALP00010040715.1" } ] } }, { "isoform_ac": "A0A8V1AEK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4/entry#A0A8V1AEK2-1", "sequence": { "sequence": "MDRVTRHMVFQFPHTRDHSDQKTRLKSPSYFLERGKDVWNPSPDRESQLEVVRSGNLYDLRAYRGERKPSKLYEDDEPDPYRLQPPNISPQKAKELEDKRKEVIRGQVVRKSSTMAEKWSSMDELNSITTESIDREQINFSAARQQFLMLEKNSPGVLFSPGYATSPRPETPSRGLRGAMVTPRGPHRAGWTRASTRCTACSTRPQGRRRAMPTDGGGSAEGSGETPIEREIRRALEREESLWKERGMQRLTSSSELVEIQTKPLLSLHTAPAQGRKGKDKGRASFNVQREIEKETKREEDLRRQGRLPGLYDRGTPQELGELRRVFEQEEQQPLPGPTPSPVLRREHFALSFWQPRISVSDGMGTRSAAGRELSPDGEHGRDEQYTLRTWRPQRSALIEEEIRSDLQREEELQEQRRRRLMDGGDGTSRESSRSRHSSGKGRADPAPRVRGCPPGDRSAPGQGGTSGCGDPHAASLSLSLSAAASGASGSYSVSGSPVSTPQKPGVLGLVTSFTPLRLSCSESSGPDSVRCSPSEERRRRTKEEGKVRRGGGGVEGEMGVPW", "length": 563, "header": "tr|A0A8V1AEK2-1|A0A8V1AEK2_CHICK Computationally mapped isoform of A-kinase anchor protein 2 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGK4-1" }, "locus": { "chromosome": "28", "start_pos": 3206275, "end_pos": 3204016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066445.1", "url": "https://www.ensembl.org/id/ENSGALT00010066445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040711.1", "url": "https://www.ensembl.org/id/ENSGALP00010040711.1" } ] } }, { "isoform_ac": "A0A8V1AEK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4/entry#A0A8V1AEK7-1", "sequence": { "sequence": "MDRVTRHMVFQFPHTRDHSDAYQGDASMDGDDDIFDYSSQKENGKDVWNPSPDRESQLEVVRSGNLYDLRAYRGERKPSKLYEDDEPDPYRLQPPNISPQKAKELEDKRKEVIRGQVVRKSSTMAEKWSSMDELNSITTESIDREQINFSAARQQFLMLEKNSPGVLFSPGYATSPRPEGRALGLARASSRDDLDSGGETPIEREIRRALEREESLWKERGMQRLTSSSELVEIQTKPLLSLHTAPAQGRKGKDKGRASFNVQREIEKETKREEDLRRQGRLPGLYDRGTPQELGELRRVFEQEEQQPAREDSTGGRLPGPTPSPVLRREHFALSFWQPRISVSDGMGTRSAAGRELSPDGEHGRDEQYTLRTWRPQRSALIEEEIRSDLQREEELQEQRRRRLMDGGDGTSRESSRSRHSSGKGRADPAPRVRGCPPGDRSAPGQGGTSGCGDPHAASLSLSLSAAASGASGSYSVSGSPVSTPQKPGVLGLVTSFTPLRLSCSESSGPDSVRCSPSEERRRRTKEEGKVRRGGGGVEGEMGVPW", "length": 546, "header": "tr|A0A8V1AEK7-1|A0A8V1AEK7_CHICK Computationally mapped isoform of A-kinase anchor protein 2 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGK4-1" }, "locus": { "chromosome": "28", "start_pos": 3206275, "end_pos": 3204016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066451.1", "url": "https://www.ensembl.org/id/ENSGALT00010066451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040716.1", "url": "https://www.ensembl.org/id/ENSGALP00010040716.1" } ] } }, { "isoform_ac": "A0A8V1AGK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4/entry#A0A8V1AGK4-1", "sequence": { "sequence": "MDRVTRHMVFQFPHTRDHSDAYQGDASMDGDDDIFDYSSQKENGKDVWNPSPDRESQLEVVRSGNLYDLRAYRGERKPSKLYEDDEPDPYRLQPPNISPQKAKELEDKRKEVIRGQVVRKSSTMAEKWTFAIYFDKPSPGRAVTPVDPESIDREQINFSAARQQFLMLEKNSPGVLFSPGYATSPRPEVTVKTSRQEWHSPPVGSSSDTVTRAERGHGDTTGPTQGGMDQSVYTVYSVQHQASGKEEGYAHGKGNTNVSQPKGRALGLARASSRDDLDSGLGEMYSAGYRSNGSDVPNGLWDVKDGGGSAEGSGETPIEREIRRALEREESLWKERGMQRLTSSSELVEIQTKPLLSLHTAPAQGRKGKDKGRASFNVQREIEKETKREEDLRRQGRLPGLYDRGTPQELGELRRVFEEDSTGGRLPGPTPSPVLRREHFALSFWQPRISVSDGMGTRSAAGRELSPDGEHGRDEQYTLRTWRPQRSALIEEEIRSDLQREEELQEQRRRRLMDGGDGTSRESSRSRHSSGKGRADPAPRVRGCPPGDRSAPGQGGTSGCGDPHAASLSLSLSAAASGASGSYSVSGSPVSTPQKPGVLGLVTSFTPLRLSCSESSGPDSVRCSPSEERRRRTKEEGKVRRGGGGVEGEMGVPW", "length": 654, "header": "tr|A0A8V1AGK4-1|A0A8V1AGK4_CHICK Isoform 1 of A-kinase anchor protein 2 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGK4-1" }, "locus": { "chromosome": "28", "start_pos": 3206275, "end_pos": 3204016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066438.1", "url": "https://www.ensembl.org/id/ENSGALT00010066438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040704.1", "url": "https://www.ensembl.org/id/ENSGALP00010040704.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 144, "start_aa": "Thr", "end_pos": 144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr144", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 224, "start_aa": "Thr", "end_pos": 224, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr224", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 430, "start_aa": "Thr", "end_pos": 430, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr430", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK4" }, { "id": "PF15304", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A-kinase anchor protein 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 350, "end_pos": 400, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 144, 224, 430 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGK5-1", "uniprot_ac": "A0A8V1AGK5", "uniprot_id": "A0A8V1AGK5_CHICK", "mass": { "chemical_mass": 68872.0, "monoisotopic_mass": 68872.0 }, "refseq": {}, "gene_names": [ { "name": "PRPF4", "type": "recommended", "evidence": [ { "id": "A0A8V1AGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ] } ], "protein_names": [ { "name": "U4/U6 small nuclear ribonucleoprotein Prp4", "type": "recommended", "evidence": [ { "id": "A0A8V1AGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5/entry#names_and_taxonomy" } ] }, { "name": "U4/U6 snRNP 60 kDa protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5/entry#names_and_taxonomy" } ] }, { "name": "WD splicing factor Prp4", "type": "synonym", "evidence": [ { "id": "A0A8V1AGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5#function" }, { "database": "UniProtKB", "id": "ARBA00035603", "url": "https://www.uniprot.org/uniprotkb/ARBA00035603#function" }, { "database": "UniProtKB", "id": "F1NNQ9", "url": "https://www.uniprot.org/uniprotkb/F1NNQ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRPF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5", "locus": { "chromosome": "17", "start_pos": 2141931, "end_pos": 2150968, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027948", "url": "https://www.ensembl.org/id/ENSGALG00010027948" } ] } } ], "crossref": [ { "id": "A0A8V1AGK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008857", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417270", "url": "https://www.ncbi.nlm.nih.gov/gene/417270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036285", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036285", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417270", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LNEPICY", "url": "https://omabrowser.org/oma/group/LNEPICY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGK5", "url": "https://www.orthodb.org/?gene=A0A8V1AGK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NNQ9", "url": "https://www.orthodb.org/?gene=F1NNQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19846", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19846", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19846:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19846:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNQ9", "url": "https://www.uniprot.org/uniprotkb/F1NNQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNQ9-1", "url": "https://www.uniprot.org/uniprotkb/F1NNQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLMICSRLLCSAPSAMPAASSPAATSDSSRCFLRLCGAERPRQGAPEAGRALAGRPHGSRAHLQVLPDAFELLDVVQLQLQPRRLPPQHHSTAAVSRPAPRGAPPLPPTKSKPSEEGDAPPAKRAPIFYGSLEEKERERLAKGESGLLGKEGMKAALEAGNINISSGEVFELEDHMSERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTRKDDDRSKKSKEEYQQTWYHEGPRSLKTARLWLANYSLPRAVKRLEEARLLKEIPEATRTSQRQELHKSLRSLNNFCSQIGDDRPLSYCHFSPNSKLLATACWSGLCKLWSVPDCNLVHTLRGHSTNVGAIVFHPKATVSLDKKDVNLASCAADGSVKLWSLESDEPVADIEGHSMRVARVMWHPSGRFLGTTCYDHSWRLWDLEAQEEILHQEGHSKGVYDIAFHTDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGLNFSPNGYHVATGSGDNTCKVWDLRQRKCIYTIPAHQNLVTGVKFEPNHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISLDGQLIATCSYDRTFKLWTAE", "length": 621, "header": "tr|A0A8V1AGK5-1|A0A8V1AGK5_CHICK Isoform 1 of U4/U6 small nuclear ribonucleoprotein Prp4 OS=Gallus gallus OX=9031 GN=PRPF4 PE=1 SV=1 CANONICAL=A0A8V1AGK5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5/entry#A0A8V1AGK5-1", "sequence": { "sequence": "MRSLMICSRLLCSAPSAMPAASSPAATSDSSRCFLRLCGAERPRQGAPEAGRALAGRPHGSRAHLQVLPDAFELLDVVQLQLQPRRLPPQHHSTAAVSRPAPRGAPPLPPTKSKPSEEGDAPPAKRAPIFYGSLEEKERERLAKGESGLLGKEGMKAALEAGNINISSGEVFELEDHMSERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTRKDDDRSKKSKEEYQQTWYHEGPRSLKTARLWLANYSLPRAVKRLEEARLLKEIPEATRTSQRQELHKSLRSLNNFCSQIGDDRPLSYCHFSPNSKLLATACWSGLCKLWSVPDCNLVHTLRGHSTNVGAIVFHPKATVSLDKKDVNLASCAADGSVKLWSLESDEPVADIEGHSMRVARVMWHPSGRFLGTTCYDHSWRLWDLEAQEEILHQEGHSKGVYDIAFHTDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGLNFSPNGYHVATGSGDNTCKVWDLRQRKCIYTIPAHQNLVTGVKFEPNHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISLDGQLIATCSYDRTFKLWTAE", "length": 621, "header": "tr|A0A8V1AGK5-1|A0A8V1AGK5_CHICK Isoform 1 of U4/U6 small nuclear ribonucleoprotein Prp4 OS=Gallus gallus OX=9031 GN=PRPF4 PE=1 SV=1 CANONICAL=A0A8V1AGK5-1" }, "locus": { "chromosome": "17", "start_pos": 2150769, "end_pos": 2142745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067741.1", "url": "https://www.ensembl.org/id/ENSGALT00010067741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041484.1", "url": "https://www.ensembl.org/id/ENSGALP00010041484.1" } ] } }, { "isoform_ac": "F1NNQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5/entry#F1NNQ9-1", "sequence": { "sequence": "MASVRAPVARGGARPAPVRAPAPPEPTKSKPSEEGDAPPAKRAPIFYGSLEEKERERLAKGESGLLGKEGMKAALEAGNINISSGEVFELEDHMSERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTRKDDDRSKKSKEEYQQTWYHEGPRSLKTARLWLANYSLPRAVKRLEEARLLKEIPEATRTSQRQELHKSLRSLNNFCSQIGDDRPLSYCHFSPNSKLLATACWSGLCKLWSVPDCNLVHTLRGHSTNVGAIVFHPKATVSLDKKDVNLASCAADGSVKLWSLESDEPVADIEGHSMRVARVMWHPSGRFLGTTCYDHSWRLWDLEAQEEILHQEGHSKGVYDIAFHTDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGLNFSPNGYHVATGSGDNTCKVWDLRQRKCIYTIPAHQNLVTGVKFEPNHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISLDGQLIATCSYDRTFKLWTAE", "length": 537, "header": "tr|F1NNQ9-1|F1NNQ9_CHICK Computationally mapped isoform of U4/U6 small nuclear ribonucleoprotein Prp4 OS=Gallus gallus OX=9031 GN=PRPF4 PE=1 SV=3 CANONICAL=A0A8V1AGK5-1" }, "locus": { "chromosome": "17", "start_pos": 2150294, "end_pos": 2142745, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067740.1", "url": "https://www.ensembl.org/id/ENSGALT00010067740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041483.1", "url": "https://www.ensembl.org/id/ENSGALP00010041483.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417270", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A7J8-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp4", "gene_name": "Prpf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSRASSTTTKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGISFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE", "length": 521 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HI03-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp4", "gene_name": "Prpf4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASSRASSTATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE", "length": 521 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LDL8-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp4", "gene_name": "PRPF4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSRASSTATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE", "length": 521 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O22212-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein PRP4-like protein", "gene_name": "LIS", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPNKDDNVSLAATAQISAPPVLQDASSLPGFSAIPPVVPPSFPPPMAPIPMMPHPPVARPPTFRPPVSQNGGVKTSDSDSESDDEHIEISEESKQVRERQEKALQDLLVKRRAAAMAVPTNDKAVRDRLRRLGEPITLFGEQEMERRARLTQLLTRYDINGQLDKLVKDHEEDVTPKEEVDDEVLEYPFFTEGPKELREARIEIAKFSVKRAAVRIQRAKRRRDDPDEDMDAETKWALKHAKHMALDCSNFGDDRPLTGCSFSRDGKILATCSLSGVTKLWEMPQVTNTIAVLKDHKERATDVVFSPVDDCLATASADRTAKLWKTDGTLLQTFEGHLDRLARVAFHPSGKYLGTTSYDKTWRLWDINTGAELLLQEGHSRSVYGIAFQQDGALAASCGLDSLARVWDLRTGRSILVFQGHIKPVFSVNFSPNGYHLASGGEDNQCRIWDLRMRKSLYIIPAHANLVSQVKYEPQEGYFLATASYDMKVNIWSGRDFSLVKSLAGHESKVASLDITADSSCIATVSHDRTIKLWTSSGNDDEDEEKETMDIDL", "length": 554 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O43172-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp4", "gene_name": "PRPF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSRASSTQATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE", "length": 522 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20053-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein PRP4", "gene_name": "PRP4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKYIALENLPVDLQHKGATQNESTADILKQLPHERLQAVLEKIPEEDLEVRRLLSILKKPEVVENEDVQQRRIRLAEILMVDEIDLENINNMENINGEEVDEEDDEDFFTPATSELIFARRFLINYSLERSRKRLQKEMERHQKFNTRQELLSRRTELQRMANLELAGSQLVSTKPISAVSLSTDDMVVATGSWAGDLQVLNSQTLQPLTQKLDSHVGKIGAIDWHPDSNNQMISCAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISDVKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGIINVWDIRKRDEGQLNQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRSIKLWN", "length": 465 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MHE2-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp4", "gene_name": "PRPF4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASTRPSSTATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGLLGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPHSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVTWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE", "length": 521 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54K20-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "prpf4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNKRIYFGAIKKENLKQKKDSINSIGSSGGGDEENQAEFLPFSKHTKRSQEQHQKVLDEYERKKRAKQVIVPTIDNLVKLKLRELLEPIILFGEKPEHRRSRLREILIERNIIDGTPLLISNKKEQEEQEQLEGSDEENFLTEGTEELKTARINISIYSLKKSQQRLLHLKKQREIELSIQKENDNLKNQFEEKQQKRIQKKLRLHQQLENDNMNIDEEEDDDDDDDGDDGDDLNMMVKIKTEFEKDMEYTVKELKNYYSSVSQIGDDRPLSMGVFSPDGKNVAIGSWSGVSKVWSVSGQKKQILAGHSQRVSCIAYHPLSGIDGNHTKNLVNIATTSADSTCKLWPLLNNDNNNNNNNNNDNEEEDNDATVSIETQPILSLEGHSDVVNRCSFHPCGRYITTSSNDKSWRLWDLESGGKCLLDQEGHSDGVMGISIQSDGSLLATGSQDGLVRIWDLRSGRPILYFQGHSKQVISVDWSPNGYQLASSSEDNTVVIWDIRKKEQSCQILAHNSIVSCVKFQKQSTQTNNNNNNSSPGCVNYLATCSFDGKIKTWSPNTWSPLATFEGHSSKVTSIDLTNSKILSTSFDKTWKIWSNDN", "length": 600 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DAW6-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp4", "gene_name": "Prpf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRASSTTTKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCSLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGDFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE", "length": 521 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VVI0-1", "protein_name": "U4-U6 small nuclear riboprotein factor 60K", "gene_name": "U4-U6-60K", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDDDDIQYIKRQRTLHYGSLEESERKRQNAAASGAAATTTSGTTASSGAGTTTTGTGGQLEDIDSDEDYEESTKKTSNAKQAGAPPPTAATLANKIDDDYFDLEMEMERDKVALLEEFERKKRARQINVSTDDTEIKSNLRQLNEPICYFGEGPAERRRRLKELLAGLGENAINKRQYEDEERKQQQREQDQATWYHEGPDSLRIARLWLADYSLPRAKDRLVRAREALEVPSAARAGRMVEMQKKLQSLAPLCSQVGDTRPVSSAAFSEDSSLLLTSSWSGLCKLWSVPDCELKQTLRGHASYVGGVALRPGVKADEENVVAMASGGHDGAVKLWGFNNEESIADITGHMPHRVSKVAFHPSGRFLATACYDSSWRLWDLEQKTEVLHQEGHAKPVHCLSYHSDGSVLVTGGLDAFGRVWDLRTGRCIMFLEGHLGAVFGVDFSPNGFHIATGSQDNTCKIWDLRRRQPVYTIPAHTNLISDVKYQQECGSFLVTCSYDSTTKIWSNKTWQPLKTLQGHDNKVISVDIAPNSQYIATTSFDRTFKLWSPDS", "length": 553 }, "evidence": [ { "id": "A0A8V1AGK5", "url": "https://omabrowser.org/oma/group/A0A8V1AGK5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "U4 snRNA binding", "id": "GO:0030621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030621", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "U4/U6 snRNP", "id": "GO:0071001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "U2-type precatalytic spliceosome", "id": "GO:0071005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGK5" }, { "id": "SM00500", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00500" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pre-mRNA processing factor 4 (PRP4)-like", "eco_id": "ECO_0000259", "start_pos": 202, "end_pos": 254, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 513, "end_pos": 515 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGL0-1", "uniprot_ac": "A0A8V1AGL0", "uniprot_id": "A0A8V1AGL0_CHICK", "mass": { "chemical_mass": 13498.0, "monoisotopic_mass": 13498.0 }, "refseq": {}, "gene_names": [ { "name": "LIM2", "type": "recommended", "evidence": [ { "id": "A0A8V1AGL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL0" } ] } ], "protein_names": [ { "name": "Lens intrinsic membrane protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AGL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LIM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL0", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGL0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGL0", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AGL0", "url": "https://www.orthodb.org/?gene=A0A8V1AGL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCAQPQLRRAACSACAVPVSPLFVPTAIWDATRALMLLAVLAAAVGFAVGLSAAGGAAWRARARVAGMAMLLAGALALLGLAVCTAGARGTAWHFSWSYILGWVGVVLIGSAGLFHLCAAAKDLSPESSETGGG", "length": 135, "header": "tr|A0A8V1AGL0-1|A0A8V1AGL0_CHICK Isoform 1 of Lens intrinsic membrane protein 2 OS=Gallus gallus OX=9031 GN=LIM2 PE=4 SV=1 CANONICAL=A0A8V1AGL0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL0/entry#A0A8V1AGL0-1", "sequence": { "sequence": "MSCAQPQLRRAACSACAVPVSPLFVPTAIWDATRALMLLAVLAAAVGFAVGLSAAGGAAWRARARVAGMAMLLAGALALLGLAVCTAGARGTAWHFSWSYILGWVGVVLIGSAGLFHLCAAAKDLSPESSETGGG", "length": 135, "header": "tr|A0A8V1AGL0-1|A0A8V1AGL0_CHICK Isoform 1 of Lens intrinsic membrane protein 2 OS=Gallus gallus OX=9031 GN=LIM2 PE=4 SV=1 CANONICAL=A0A8V1AGL0-1" }, "locus": { "chromosome": "25", "start_pos": 132335, "end_pos": 130851, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068986.1", "url": "https://www.ensembl.org/id/ENSGALT00010068986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042428.1", "url": "https://www.ensembl.org/id/ENSGALP00010042428.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGL5-1", "uniprot_ac": "A0A8V1AGL5", "uniprot_id": "A0A8V1AGL5_CHICK", "mass": { "chemical_mass": 61971.0, "monoisotopic_mass": 61971.0 }, "refseq": { "ac": "XP_015151546", "name": "GPI transamidase component PIG-S", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151546" }, "gene_names": [ { "name": "PIGS", "type": "recommended", "evidence": [ { "id": "A0A8V1AGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5" } ] }, { "name": "PIGS", "type": "synonym", "evidence": [ { "id": "XP_015151546", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151546" } ] } ], "protein_names": [ { "name": "GPI transamidase component PIG-S", "type": "synonym", "evidence": [ { "id": "XP_015151546", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151546" } ] }, { "name": "Phosphatidylinositol glycan anchor biosynthesis class S", "type": "synonym", "evidence": [ { "id": "A0A8V1AGL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151546.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151546" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIGS", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5", "locus": { "chromosome": "19", "start_pos": 6217075, "end_pos": 6221432, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029201", "url": "https://www.ensembl.org/id/ENSGALG00010029201" } ] } } ], "crossref": [ { "id": "A0A8V1AGL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "417571", "url": "https://www.ncbi.nlm.nih.gov/gene/417571", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417571", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417571", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AEHKYAV", "url": "https://omabrowser.org/oma/group/AEHKYAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGL5", "url": "https://www.orthodb.org/?gene=A0A8V1AGL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21072:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21072:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10510", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10510", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151546", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151546", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELGVSPAFAVGREEKMAAAAVAADEAERSRGRRAALSFAAIAVLLGLPLWWKTTETYRAALPYGDIAALGRLPFQVAVSVSVVFLPGSVPADLPRRLPYGDVREERVPVSSRSDVASRTETAYRGSTAREEAALGAATAREADAALRALQDSPPGSLTVYVLPEASSLLPQGVNVYVGKHRSALVRAGQGLATLHARLQQLMQVMSFTASSIAAALSDRVPDGQLGPDAWRHLKSSLGYEITFSLLNPDPKSHDVDWDIEGAVNHYVQPILDKLNLVANFSVDSQILYYAVLGVTPRFDKESSSFILSAHSLPHVINPVEARLGSSAASLYPVLNFLLYVPERSHSPLYIQDKDGAPVTTNAFHSPRWGGIMIYNVEVPASPQTSLPLRVDVDMVRVMEVFLAQLRLLFGISREELPPEFLVESPGNEGLADWELDHLLWAHTLENIATVSTTLTSLAQLLDQISNIVIKDDVASEVYRAVAAAQDAVAELAEGRLRSAFQASKEAVTSSERAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLAKMLREARQSKKEPTKMD", "length": 569, "header": "tr|A0A8V1AGL5-1|A0A8V1AGL5_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class S OS=Gallus gallus OX=9031 GN=PIGS PE=1 SV=1 CANONICAL=A0A8V1AGL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5/entry#A0A8V1AGL5-1", "sequence": { "sequence": "MAELGVSPAFAVGREEKMAAAAVAADEAERSRGRRAALSFAAIAVLLGLPLWWKTTETYRAALPYGDIAALGRLPFQVAVSVSVVFLPGSVPADLPRRLPYGDVREERVPVSSRSDVASRTETAYRGSTAREEAALGAATAREADAALRALQDSPPGSLTVYVLPEASSLLPQGVNVYVGKHRSALVRAGQGLATLHARLQQLMQVMSFTASSIAAALSDRVPDGQLGPDAWRHLKSSLGYEITFSLLNPDPKSHDVDWDIEGAVNHYVQPILDKLNLVANFSVDSQILYYAVLGVTPRFDKESSSFILSAHSLPHVINPVEARLGSSAASLYPVLNFLLYVPERSHSPLYIQDKDGAPVTTNAFHSPRWGGIMIYNVEVPASPQTSLPLRVDVDMVRVMEVFLAQLRLLFGISREELPPEFLVESPGNEGLADWELDHLLWAHTLENIATVSTTLTSLAQLLDQISNIVIKDDVASEVYRAVAAAQDAVAELAEGRLRSAFQASKEAVTSSERAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLAKMLREARQSKKEPTKMD", "length": 569, "header": "tr|A0A8V1AGL5-1|A0A8V1AGL5_CHICK Isoform 1 of Phosphatidylinositol glycan anchor biosynthesis class S OS=Gallus gallus OX=9031 GN=PIGS PE=1 SV=1 CANONICAL=A0A8V1AGL5-1" }, "locus": { "chromosome": "19", "start_pos": 6221233, "end_pos": 6217446, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070567.1", "url": "https://www.ensembl.org/id/ENSGALT00010070567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043258.1", "url": "https://www.ensembl.org/id/ENSGALP00010043258.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417571", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417571", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IK45-1", "protein_name": "GPI transamidase component PIG-S", "gene_name": "Pigs", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAAGASATDLELVRGKRAALFFAAVAILLGLPLWWKTTETYRAPLPYSQISRLNALQLRLTVPVTVVFTRDSVPLDDQLKLPFTVVHEREIPLKYKLKIKCRFQKAYRRALDHEEEALSLGNVHEAEAVLFEPEKQAEGSLTVYMISEHSSLLPQDVMSYIGPERTAVVRGIMHREALNIIGRRIIQIAQAMSLTEDVLAAALADHLPEDKWSSDKRRPLKSSLGYEITFSLLNPDPKSHDVHWDIEGAVQRYVQPFLNALSAAGNFSVDSQILYYAMLGVNPRFDPASSSYYLAMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPELAHSPLYIQDKDGAPVATNAFHSPRWGGIMIYNVDPKIYNASDLPVKVEVDMVQVMEVFLAQLKLLFGITQPQVPPKCLLSGPKSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYRAVAAVQKAAEELALGHLSSAFVASQEAVTSSERAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFLETHKSWKKPEKVD", "length": 555 }, "evidence": [ { "id": "A0A8V1AGL5", "url": "https://omabrowser.org/oma/group/A0A8V1AGL5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q04080-1", "protein_name": "GPI transamidase component GPI17", "gene_name": "GPI17", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSNANLRKWVGFCFVAIYLFLGVPLWYKLTTVYRASLPINYIESLQNNKFQDIHLVIPVYVKSDTYRFPDVHDAIQVQVNHLLNSQEQRVPWSLQVLPYNETIEQMESEGNQFHVVTLKLDEFIGYSSAYDTKETLVYYDDAAVLSNDLPFFVAQTLVEHTFQLEWTHLNKTCEGVSTNNDVAISYDPNIHLSVTLLSGDGNPVAWEIEPTLTDYFSPFRKFLSPLVNFTVDSSIVYHNDLNLHSLNGSCTSVTWFDLSHTIDLSELSSMAYYPEDSALNLAIVFPSASSSPDGLAFINGTRISDEITTLDWNSYLVPQWGVIIINKMPLKPNSVISEDYLEPMMYRFATDIFQLLGLTEGSQDLLSPYITIDSFKRLTILQNLDKATETLWSLVKLTQQFQGMSIPREVSDNVIEALDLRLQIIDLLNDPGKGGDIVWNNALHLSNELVKLCEKAFFNGEMVQQNFFPQEHMIAVYLPLLGPISAVMFFGFYNVMKEKNQKSKKNGTEREVAKEKLELKEAQKLHAIDGEDEL", "length": 534 }, "evidence": [ { "id": "A0A8V1AGL5", "url": "https://omabrowser.org/oma/group/A0A8V1AGL5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XI31-1", "protein_name": "GPI-anchor transamidase component PIGS", "gene_name": "Pigs", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATAGAAATDLEVVRGKRAALFFAAVAILLGLPLWWKTTETYRAPLPYSEISGLNALQLRLMVPVTVVFTRDSVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALEHEEEALSLGSVHEAEALLAEPEKQAEGSLTVYVISEHSSLLPQDMMSYIGPERTAIVRGMIHREAFNIIGRRIIHVAQAMSLTEDVLAAALADHLPEDKWSSDKRRPLKSSLGYEITFSLLNPDPKSHDVHWDIEEGVQRYVQPFLNRLSAAGNFSVDSQILYYAMLGVNPRFDPASSSYSLAMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPELAHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDPKIYNASELPVRVEVDMAQVMEVFLAQLRLLFGIAQPQVPPKCLLSGPKSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYRAVAAVQKAAEALALGHLSSAFAASQEAVTSSERAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFLETHKSWKKPEKID", "length": 555 }, "evidence": [ { "id": "A0A8V1AGL5", "url": "https://omabrowser.org/oma/group/A0A8V1AGL5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PD26-1", "protein_name": "GPI-anchor transamidase component PIGS", "gene_name": "Pigs", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGAAATDLEVVRGKRSALFFAAVAILLGLPLWWKTTETYRAPLPYSDISGLNALLLRLMVPVTVVFTRDSVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALEHEEEALSLGSVHEAEAMLAEPEKQAEGSLTVYVISEHSSLLPQDMMSYIGPERTAVVRGLIHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSSDKRRPLKSSLGYEITFSLLNPDPKSHDVHWDIEGAVQRFVQPFLNRLSVAGNFSVDSQILYYAMLGVNPRFDPASSSYSLAMHSLPHVINPVESRLGSSAASLYPVLHFLLYVPELAHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDPKIYNASELPVRVEVDMVRVMEVFLAQLRLLFGIAQPQVPPKCLLSGPKSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYRAVAAVQKAAKALALGHLSSAFAASQEAVTSSERAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFQETRKSWKKPEKID", "length": 555 }, "evidence": [ { "id": "A0A8V1AGL5", "url": "https://omabrowser.org/oma/group/A0A8V1AGL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96S52-1", "protein_name": "GPI-anchor transamidase component PIGS", "gene_name": "PIGS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAGAAATHLEVARGKRAALFFAAVAIVLGLPLWWKTTETYRASLPYSQISGLNALQLRLMVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHSSLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSHDVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPELAHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFLETRKSWRKPEKTD", "length": 555 }, "evidence": [ { "id": "A0A8V1AGL5", "url": "https://omabrowser.org/oma/group/A0A8V1AGL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VC10-1", "protein_name": "Phosphatidylinositol glycan anchor biosynthesis class S", "gene_name": "PIG-S", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METSSSSPVKPRRKDKDEDKFRIGATLAFIVVIIGIGVPMWWRTTTVYRVNLPSTEILSLSKIPIKTAVQVAIYTQQTSRGQLLIAELQNAFSDNEIWSVEFKQLSPTPMTQEAHTPAALEKLLLENHVQSVGDFMFIEWPKLQEELLLTTERSALMRSDTPSNKIAQLLHAKILQTYRINQILSTDERMGAKSEAPQPAYDVIVSVLNPKPRLTHAKWNIAMAVKTYIEPWLAKVSGVSNYTVRSQWKYRVAIEADLKQVRDQSKLGRHYALQETALPHLLTSIAQNLSASTTDKPAINLVVYIPPCHIAPLHIYNSKDQRLTRNDVDAFISPPWGGFIIANPPEHVCLAAMSDQEAVPYHVSTTDNMQVMLDQLHKLLDISSELQMEGVKVVDIEQLEPRRWEYEAYLRRSAIRHISTASSTLQSLIKLLDQISYIVIDDEVGAAITNSYADILAAKAALLEHRLADASVLAKRAFVASERGFFDASLLAQLYFPDEQKYAIYIPLFLPIMVPVLSSFNMLRGVLQARRKEKQS", "length": 536 }, "evidence": [ { "id": "A0A8V1AGL5", "url": "https://omabrowser.org/oma/group/A0A8V1AGL5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5" } ], "pmid": "" }, { "name": "attachment of GPI anchor to protein", "id": "GO:0016255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "GPI-anchor transamidase complex", "id": "GO:0042765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGM4-1", "uniprot_ac": "A0A8V1AGM4", "uniprot_id": "A0A8V1AGM4_CHICK", "mass": { "chemical_mass": 79612.0, "monoisotopic_mass": 79612.0 }, "refseq": {}, "gene_names": [ { "name": "LOC101750583", "type": "recommended", "evidence": [ { "id": "A0A8V1AGM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4" } ] } ], "protein_names": [ { "name": "ZMYM2-like/QRICH1 C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AGM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101750583", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGM4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750583", "url": "https://www.ncbi.nlm.nih.gov/gene/101750583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750583", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750583", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NLVIWAH", "url": "https://omabrowser.org/oma/group/NLVIWAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A979", "url": "https://www.orthodb.org/?gene=A0A8V1A979", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGM4", "url": "https://www.orthodb.org/?gene=A0A8V1AGM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46963:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46963:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A979", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A979", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A979-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A979-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVSSLPVASKTDFCTHPHMESSQICSASRKFESITDEDYSNVSSLCEDLSNLVTWAHTHGAICIHIPALETMQNMGQPSKDNSVLWICGAGHAYHWTCEDLHFGSRKENEAAEKRKRQTSFGAPSRGTALGEKRIKIASSFERVRRDSAATGSRGTPAGSSQQKDTICIIRNEQPARQNRRKSRSMQPGSAAEQRLSVSIGEIRTDLCEMKLECSEDLHVISDDEQYVLNAEHQEERINQNILSQSPPEDVSAEVGLRMYCDQKTEINKQTVTSASGFIPTTTPTPALCCTLKSPGRDRKILESSFLSLGPLNPTEFTREHSTARDSSGSATPKEDLELIPISNTEAKAQREPPAPVMFFELEATVDVQQQIHLSSSEFSVSGTLDLNGNATEGPAEESRLSGSEQAPRPSASLSTESRNANQPPEPSETNVLSKRNRNAANIRVFREWLDVHCPSEAREIYKLPPKDLDNYLALFYTSAKKQNGTDFSTGSLQFFQSSIDRYLKDHSYKYSVVKGAEFRASQEALKQKHQLLFQREREENWTLLENLTDENVDHLRNKGLLSQSNPQGFLHLMFVNIIRGFGASTHNKGQNLYWGQLVLRRDVAGLEYLEWKHDLNADGAVGESVPHLFARPNSPENCPVQDYKKYAEKRPGDMLHDYDPLYLSPRHMYSVWDQVWYSRKSLTTAKIGNMLKVILRQVKASEKKLRK", "length": 709, "header": "tr|A0A8V1AGM4-1|A0A8V1AGM4_CHICK Isoform 1 of ZMYM2-like/QRICH1 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101750583 PE=4 SV=1 CANONICAL=A0A8V1AGM4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A979-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4/entry#A0A8V1A979-1", "sequence": { "sequence": "MFESITDEDYSNVSSLCEDLSNLVTWAHTHGAICIHIPALETMQNMGQPSKDNSVLWICGAGHAYHWTCEDLHFGSRKENEAAEKRKRQTSFGAPSRGTALGEKRIKIASSFERVRRDSAATGSRGTPAGSSQQKDTICIIRNEQPARQNRRKSRSMQPGSAAEQRLSVSIGEIRTDLCEMKLECSEDLHVISDDEQYVLNAEHQEERINQNILSQSPPEDVSAEVGLRMYCDQKTEINKQTVTSASGFIPTTTPTPALCCTLKSPGRDRKILESSFLSLGPLNPTEFTREHSTARDSSGSATPKEDLELIPISNTEAKAQREPPAPVMFFELEATVDVQQQIHLSSSEFSVSGTLDLNGNATEGPAEESRLSGSEQAPRPSASLSTESRNANQPPEPSETNVLSKRNRNAANIRVFREWLDVHCPSEAREIYKLPPKDLDNYLALFYTSAKKQNGTDFSTGSLQFFQSSIDRYLKDHSYKYSVVKGAEFRASQEALKQKHQLLFQREREENWTLLENLTDENVDHLRNKGLLSQSNPQGFLHLMFVNIIRGFGASTHNKGQNLYWGQLVLRRDVAGLEYLEWKHDLNADGAVGESVPHLFARPNSPENCPVQDYKKYAEKRPGDMLHDYDPLYLSPRHMYSVWDQVWYSRKSLTTAKIGNMLKVILRQVKASEKKLRK", "length": 679, "header": "tr|A0A8V1A979-1|A0A8V1A979_CHICK Computationally mapped isoform of ZMYM2-like/QRICH1 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101750583 PE=4 SV=1 CANONICAL=A0A8V1AGM4-1" }, "locus": { "chromosome": "28", "start_pos": 3212673, "end_pos": 3208171, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066470.1", "url": "https://www.ensembl.org/id/ENSGALT00010066470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040725.1", "url": "https://www.ensembl.org/id/ENSGALP00010040725.1" } ] } }, { "isoform_ac": "A0A8V1AGM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4/entry#A0A8V1AGM4-1", "sequence": { "sequence": "MGVSSLPVASKTDFCTHPHMESSQICSASRKFESITDEDYSNVSSLCEDLSNLVTWAHTHGAICIHIPALETMQNMGQPSKDNSVLWICGAGHAYHWTCEDLHFGSRKENEAAEKRKRQTSFGAPSRGTALGEKRIKIASSFERVRRDSAATGSRGTPAGSSQQKDTICIIRNEQPARQNRRKSRSMQPGSAAEQRLSVSIGEIRTDLCEMKLECSEDLHVISDDEQYVLNAEHQEERINQNILSQSPPEDVSAEVGLRMYCDQKTEINKQTVTSASGFIPTTTPTPALCCTLKSPGRDRKILESSFLSLGPLNPTEFTREHSTARDSSGSATPKEDLELIPISNTEAKAQREPPAPVMFFELEATVDVQQQIHLSSSEFSVSGTLDLNGNATEGPAEESRLSGSEQAPRPSASLSTESRNANQPPEPSETNVLSKRNRNAANIRVFREWLDVHCPSEAREIYKLPPKDLDNYLALFYTSAKKQNGTDFSTGSLQFFQSSIDRYLKDHSYKYSVVKGAEFRASQEALKQKHQLLFQREREENWTLLENLTDENVDHLRNKGLLSQSNPQGFLHLMFVNIIRGFGASTHNKGQNLYWGQLVLRRDVAGLEYLEWKHDLNADGAVGESVPHLFARPNSPENCPVQDYKKYAEKRPGDMLHDYDPLYLSPRHMYSVWDQVWYSRKSLTTAKIGNMLKVILRQVKASEKKLRK", "length": 709, "header": "tr|A0A8V1AGM4-1|A0A8V1AGM4_CHICK Isoform 1 of ZMYM2-like/QRICH1 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101750583 PE=4 SV=1 CANONICAL=A0A8V1AGM4-1" }, "locus": { "chromosome": "28", "start_pos": 3218515, "end_pos": 3208171, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066469.1", "url": "https://www.ensembl.org/id/ENSGALT00010066469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040724.1", "url": "https://www.ensembl.org/id/ENSGALP00010040724.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 286, "start_aa": "Thr", "end_pos": 286, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr286", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101750583", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750583", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM4" }, { "id": "PF12012", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012" } ], "ann_type": 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"MGGGERRGGSAAMRGARVSAAQRRPLQELRLQQGAERTNITPLLRRLRLKDHDGGTPAPRARCPSGRVAPGLPRTAVPCAPCSTDPEPLGPMKIPSGNATPDPISISEPVGHATPVTDAPEPPGDATSGPDTLVPPRDAPQEDSPPETPSGAPREPHGSAPVPIFPFSPSHLPPLPPSPDHPSSTPLEQRTPDPVGSTSIGPCALDTPGSPSPGPPGTSTPQDTPFRRWRVAPPDLSCSPVASQPLSENRDVGTPPHRSTLGMAGSPGTAPPEQCSPQVEAVGSEPVESAVAAAATPVPSSEPSLGAVSWIMPLVWLERTLPASSLLESLRHSLSVSWRDAGTNITPVPTAAVSTGVTPVPTIPVGSCVTPVPTVSTGTTVTPVPTIPVGSNVTPVPTMATGTSVTPVPTGSIATNVTPVPTGSIATNVTPVPTGSIGTSITPVPTMSMGTSVTPVPTMSTGTSVTPVLTLSTGTTMTPEERSAGTSMPAGAKDSAAETDSLLWHCPREQLRSLPRAELEGRLESTLIIIEALSLQLRDWQDCQRPLPAVGPAGQRDAHTQTDVTRPRGEEGIYHSLYVELQKKVQAVQRQRGAEQELAQQLARAAEAMDAWAGQRRALRDVADAALQGVQDEHAALEQERLQVRAMVSRCEAVLHGVPAKLQSCLQERDAAQQRADEALRAKQESDGFLEAFRSHAAAQIGARTQSLELQQELSALLAAAVQQQVSLAAEAQPFREFIDVTFASLQEERGALDGEREQVRALVSRCMTALRDVPSKLHSCLQERDAALQRVEEALQAKKEVSHQLEETLEALQDAVAQGEQLAVTNSRLSTDLSTVMKQLASLQQEQDALQQDYEEQKEKMSWLTKERDALQRERRELQEAVECREFLDQENRMSRRQLMEVEAKLQSTLAELQERSLQHEELLEAHQSLQEERAALHKELESTKAELQDLQLKRDRVSWCSAGIAESKARLQELADCLRAALPHQDDDDEVPSRSKTWTPGWRTPRGPWTPRSSAWTPVCRTPARHTPHHARASFVGSVLKAVSGRALCPSADGDEGTEGESTSARDRAASTPKPPEPEDGLMEQAAELRAVVSDLSALSSRIQELEQSEFRALQAEISDLQLQLEEVTTESQERMDAQAATIAKLNKVLQGKLQNEKELQDVVKQQEAKMLQLIDKSGEVTRLKEEVTQLKRSLQRAETEAKVLWEEMRGQEAKGDAAHVQERVLLRQEVDKLRLLLLEKEDEKVVVSGNYLEQVRGLELRLSQAQKMLRSQEELQEKVKEVLLALPELPPELRALLQHVGLKPNSEKAPAAL", "length": 1316, "header": "tr|A0A8V1AGN1-1|A0A8V1AGN1_CHICK Isoform 1 of Sperm associated antigen 5 OS=Gallus gallus OX=9031 GN=SPAG5 PE=4 SV=1 CANONICAL=A0A8V1AGN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN1/entry#A0A8V1AGM7-1", "sequence": { "sequence": "MRGARVSADHDGGTPAPRARCPSGRVAPGLPRTAVPCAPCSTDPEPLGPMKIPSGNATPDPISISEPVGHATPVTDAPEPPGDATSGPDTLVPPRDAPQEDSPPETPSGAPREPHGSAPVPIFPFSPSHLPPLPPSPDHPSSTPLEQRTPDPVGSTSIGPCALDTPGSPSPGPPGTSTPQDTPFRRWRVAPPDLSCSPVASQPLSENRDVGTPPHRSTLGMAGSPGTAPPEQCSPQVEAVGSEPVESAVAAAATPVPSSEPSLGAVSWIMPLVWLERTLPASSLLESLRHSLSVSWRDAGTNITPVPTAAVSTGVTPVPTIPVGSCVTPVPTVSTGTTVTPVPTIPVGSNVTPVPTMATGTSVTPVPTGSIATNVTPVPTGSIATNVTPVPTGSIGTSITPVPTMSMGTSVTPVPTMSTGTSVTPVLTLSTGTTMTPEERSAGTSMPAGAKDSAAETDSLLWHCPREQLRSLPRAELEGRLESTLIIIEALSLQLRDWQDCQRPLPAVGPAGQRDAHTQTDVTRPRGEEGIYHSLYVELQKKVQAVQRQRGAEQELAQQLARAAEAMDAWAGQRRALRDVADAALQGVQDEHAALEQERLQVRAMVSRCEAVLHGVPAKLQSCLQERDAAQQRADEALRAKQESDGFLEAFRSHAAAQIGARTQSLELQQELSALLAAAVQQQVSLAAEAQPFREFIDVTFASLQEERGALDGEREQVRALVSRCMTALRDVPSKLHSCLQERDAALQRVEEALQAKKEVSHQLEETLEALQDAVAQGEQLAVTNSRLSTDLSTVMKQLASLQQEQDALQQDYEEQKEKMSWLTKERDALQRERRELQEAVECREFLDQENRMSRRQLMEVEAKLQSTLAELQERSLQHEELLEAHQSLQEERAALHKELESTKAELQDLQLKRDRVSWCSAGIAESKARLQELADCLRAALPHQDDDDEVPSRSKTWTPGWRTPRGPWTPRSSAWTPVCRTPARHTPHHARASFVGSVLKAVSGRDGDEGTEGESTSARDRAASTPKPPEPEDGLMEQAAELRAVVSDLSALSSRIQELEQSEFRALQAEISDLQLQLEEVTTESQERMDAQAATIAKLNKVLQGKLQNEKELQDVVKQQEAKMLQLIDKSGEVTRLKEEVTQLKRSLQRAETEAKVLWEEMRGQEAKGDAAHVQERVLLRQEVDKLRLLLLEKEDEKVVVSGNYLEQVRGLELRLSQAQKMLRSQEELQEKVKEVLLALPELPPELRALLQHVGLKPNSEKAPAAL", "length": 1268, "header": "tr|A0A8V1AGM7-1|A0A8V1AGN1_CHICK Computationally mapped isoform of Sperm associated antigen 5 OS=Gallus gallus OX=9031 GN=SPAG5 PE=4 SV=1 CANONICAL=A0A8V1AGN1-1" }, "locus": { "chromosome": "19", "start_pos": 6233782, "end_pos": 6226900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070582.1", "url": "https://www.ensembl.org/id/ENSGALT00010070582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043273.1", "url": "https://www.ensembl.org/id/ENSGALP00010043273.1" } ] } }, { "isoform_ac": "A0A8V1AGN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN1/entry#A0A8V1AGN1-1", "sequence": { "sequence": "MGGGERRGGSAAMRGARVSAAQRRPLQELRLQQGAERTNITPLLRRLRLKDHDGGTPAPRARCPSGRVAPGLPRTAVPCAPCSTDPEPLGPMKIPSGNATPDPISISEPVGHATPVTDAPEPPGDATSGPDTLVPPRDAPQEDSPPETPSGAPREPHGSAPVPIFPFSPSHLPPLPPSPDHPSSTPLEQRTPDPVGSTSIGPCALDTPGSPSPGPPGTSTPQDTPFRRWRVAPPDLSCSPVASQPLSENRDVGTPPHRSTLGMAGSPGTAPPEQCSPQVEAVGSEPVESAVAAAATPVPSSEPSLGAVSWIMPLVWLERTLPASSLLESLRHSLSVSWRDAGTNITPVPTAAVSTGVTPVPTIPVGSCVTPVPTVSTGTTVTPVPTIPVGSNVTPVPTMATGTSVTPVPTGSIATNVTPVPTGSIATNVTPVPTGSIGTSITPVPTMSMGTSVTPVPTMSTGTSVTPVLTLSTGTTMTPEERSAGTSMPAGAKDSAAETDSLLWHCPREQLRSLPRAELEGRLESTLIIIEALSLQLRDWQDCQRPLPAVGPAGQRDAHTQTDVTRPRGEEGIYHSLYVELQKKVQAVQRQRGAEQELAQQLARAAEAMDAWAGQRRALRDVADAALQGVQDEHAALEQERLQVRAMVSRCEAVLHGVPAKLQSCLQERDAAQQRADEALRAKQESDGFLEAFRSHAAAQIGARTQSLELQQELSALLAAAVQQQVSLAAEAQPFREFIDVTFASLQEERGALDGEREQVRALVSRCMTALRDVPSKLHSCLQERDAALQRVEEALQAKKEVSHQLEETLEALQDAVAQGEQLAVTNSRLSTDLSTVMKQLASLQQEQDALQQDYEEQKEKMSWLTKERDALQRERRELQEAVECREFLDQENRMSRRQLMEVEAKLQSTLAELQERSLQHEELLEAHQSLQEERAALHKELESTKAELQDLQLKRDRVSWCSAGIAESKARLQELADCLRAALPHQDDDDEVPSRSKTWTPGWRTPRGPWTPRSSAWTPVCRTPARHTPHHARASFVGSVLKAVSGRALCPSADGDEGTEGESTSARDRAASTPKPPEPEDGLMEQAAELRAVVSDLSALSSRIQELEQSEFRALQAEISDLQLQLEEVTTESQERMDAQAATIAKLNKVLQGKLQNEKELQDVVKQQEAKMLQLIDKSGEVTRLKEEVTQLKRSLQRAETEAKVLWEEMRGQEAKGDAAHVQERVLLRQEVDKLRLLLLEKEDEKVVVSGNYLEQVRGLELRLSQAQKMLRSQEELQEKVKEVLLALPELPPELRALLQHVGLKPNSEKAPAAL", "length": 1316, "header": "tr|A0A8V1AGN1-1|A0A8V1AGN1_CHICK Isoform 1 of Sperm associated antigen 5 OS=Gallus gallus OX=9031 GN=SPAG5 PE=4 SV=1 CANONICAL=A0A8V1AGN1-1" }, "locus": { "chromosome": "19", "start_pos": 6233818, "end_pos": 6226900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070587.1", "url": "https://www.ensembl.org/id/ENSGALT00010070587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043278.1", "url": "https://www.ensembl.org/id/ENSGALP00010043278.1" } ] } }, { "isoform_ac": "A0A8V1AIR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN1/entry#A0A8V1AIR7-1", "sequence": { "sequence": "MGGGERRGGSAAMRGARVSAAQRRPLQELRLQQGAERTNITPLLRRLRLKDHDGGTPAPRARCPSGRVAPGLPRTAVPCAPCSTDPEPLGPMKIPSGNATPDPISISEPVGHATPVTDAPEPPGDATSGPDTLVPPRDAPQEDSPPETPSGAPREPHGSAPVPIFPFSPSHLPPLPPSPDHPSSTPLEQRTPDPVGSTSIGPCALDTPGSPSPGPPGTSTPQDTPFRRWRVAPPDLSCSPVASQPLSENRDVGTPPHRSTLGMAGSPGTAPPEQCSPQVEAVGSEPVESAVAAAATPVPSSEPSLGAVSWIMPLVWLERTLPASSLLESLRHSLSVSWRDAGTNITPVPTAAVSTGVTPVPTIPVGSCVTPVPTVSTGTTVTPVPTIPVGSNVTPVPTMATGTSVTPVPTGSIATNVTPVPTGSIATNVTPVPTGSIGTSITPVPTMSMGTSVTPVPTMSTGTSVTPVLTLSTGTTMTPEERSAGTSMPAGAKDSAAETDSLLWHCPREQLRSLPRAELEGRLESTLIIIEALSLQLRDWQDCQRPLPAVGPAGQRDAHTQTDVTRPRGEEGIYHSLYVELQKKVQAVQRQRGAEQELAQQLARAAEAMDAWAGQRRALRDVADAALQGVQDEHAALEQERLQVRAMVSRCEAVLHGVPAKLQSCLQERDAAQQRADEALRAKQESDGFLEAFRSHAAAQIGARTQSLELQQELSALLAAAVQQQVSLAAEAQPFREFIDVTFASLQEERGALDGEREQVRALVSRCMTALRDVPSKLHSCLQERDAALQRVEEALQAKKEVSHQLEETLEALQDAVAQGEQLAVTNSRLSTDLSTVMKQLASLQQEQDALQQDYEEQKEKMSWLTKERDALQRERRELQEAVECREFLDQENRMSRRQLMEVEAKLQSTLAELQERSLQHEELLEAHQSLQEERAALHKELESTKAELQDLQLKRDRVSWCSAGIAESKARLQELADCLRAALPHQDDDDEVPSRSKTWTPGWRTPRGPWTPRSSAWTPVCRTPARHTPHHARASFVGSVLKAVSGRDGDEGTEGESTSARDRAASTPKPPEPEDGLMEQAAELRAVVSDLSALSSRIQELEQSEFRALQAEISDLQLQLEEVTTESQERMDAQAATIAKLNKVLQGKLQNEKELQDVVKQQEAKMLQLIDKSGEVTRLKEEVTQLKRSLQRAETEAQPSTEDAAEPGGAAGEGEGGPAGPPRAAPGAPCPPAARGVEAKQRESSGCSVTHSAETFLCLTPSLFIE", "length": 1267, "header": "tr|A0A8V1AIR7-1|A0A8V1AIR7_CHICK Computationally mapped isoform of Sperm associated antigen 5 OS=Gallus gallus OX=9031 GN=SPAG5 PE=4 SV=1 CANONICAL=A0A8V1AGN1-1" }, "locus": { "chromosome": "19", "start_pos": 6233818, "end_pos": 6226847, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070589.1", "url": "https://www.ensembl.org/id/ENSGALT00010070589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043280.1", "url": "https://www.ensembl.org/id/ENSGALP00010043280.1" } ] } }, { "isoform_ac": "A0A8V1AKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN1/entry#A0A8V1AKV5-1", "sequence": { "sequence": "MRGARVSAAQRRPLQELRLQQGAERTNITPLLRRLRLKDHDGGTPAPRARCPSGRVAPGLPRTAVPCAPCSTDPEPLGPMKIPSGNATPDPISISEPVGHATPVTDAPEPPGDATSGPDTLVPPRDAPQEDSPPETPSGAPREPHGSAPVPIFPFSPSHLPPLPPSPDHPSSTPLEQRTPDPVGSTSIGPCALDTPGSPSPGPPGTSTPQDTPFRRWRVAPPDLSCSPVASQPLSENRDVGTPPHRSTLGMAGSPGTAPPEQCSPQVEAVGSEPVESAVAAAATPVPSSEPSLGAVSWIMPLVWLERTLPASSLLESLRHSLSVSWRDAGTNITPVPTAAVSTGVTPVPTIPVGSCVTPVPTVSTGTTVTPVPTIPVGSNVTPVPTMATGTSVTPVPTGSIATNVTPVPTGSIATNVTPVPTGSIGTSITPVPTMSMGTSVTPVPTMSTGTSVTPVLTLSTGTTMTPEERSAGTSMPAGAKDSAAETDSLLWHCPREQLRSLPRAELEGRLESTLIIIEALSLQLRDWQDCQRPLPAVGPAGQRDAHTQTDVTRPRGEEGIYHSLYVELQKKVQAVQRQRGAEQELAQQLARAAEAMDAWAGQRRALRDVADAALQGVQDEHAALEQERLQVRAMVSRCEAVLHGVPAKLQSCLQERDAAQQRADEALRAKQESDGFLEAFRSHAAAQIGARTQSLELQQELSALLAAAVQQQVSLAAEAQPFREFIDVTFASLQEERGALDGEREQVRALVSRCMTALRDVPSKLHSCLQERDAALQRVEEALQAKKEVSHQLEETLEALQDAVAQGEQLAVTNSRLSTDLSTVMKQLASLQQEQDALQQDYEEQKEKMSWLTKERDALQRERRELQEAVECREFLDQENRMSRRQLMEVEAKLQSTLAELQERSLQHEELLEAHQSLQEERAALHKELESTKAELQDLQLKRDRVSWCSAGIAESKARLQELADCLRAALPHQDDDDEVPSRSKTWTPGWRTPRGPWTPRSSAWTPVCRTPARHTPHHARASFVGSVLKAVSGRDGDEGTEGESTSARDRAASTPKPPEPEDGLMEQAAELRAVVSDLSALSSRIQELEQSEFRALQAEISDLQLQLEEVTTESQERMDAQAATIAKLNKVLQGKLQNEKELQDVVKQQEAKMLQLIDKSGEVTRLKEEVTQLKRSLQRAETEAKGDAAHVQERVLLRQEVDKLRLLLLEKEDEKVVVSGNYLEQVRGLELRLSQAQKMLRSQEELQEKVKEVLLALPELPPELRALLQHVGLKPNSEKAPAAL", "length": 1286, "header": "tr|A0A8V1AKV5-1|A0A8V1AKV5_CHICK Computationally mapped isoform of Sperm associated antigen 5 OS=Gallus gallus OX=9031 GN=SPAG5 PE=4 SV=1 CANONICAL=A0A8V1AGN1-1" }, "locus": { "chromosome": "19", "start_pos": 6233782, "end_pos": 6226900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070588.1", "url": "https://www.ensembl.org/id/ENSGALT00010070588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043279.1", "url": "https://www.ensembl.org/id/ENSGALP00010043279.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 374, "start_aa": "Thr", "end_pos": 374, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr374", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN1" } ], "pmid": "" }, { "name": "regulation of attachment of spindle microtubules to kinetochore", "id": "GO:0051988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051988", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 374 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 344, "end_pos": 346 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MITSTPAQTTSVPGTSSPSPASSTPTTTRNPAQTTLLPGTSTPTPASSAPPTTSTPAQTTSVPATLTPNTASSTLMTASTLAQTTSLPGTSSRTPASSAPPTTRTPAQTKSSLQLNSSPTSISSALSTTTTPAQTTSVPGTSSPNTASSALLTTTTPAQTTSVPGTSSPNTASSALLTTSTPAQTTTVPATSTPTPASSALPTTSTPAQRTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSTPTRASSTLMTRSTLAQTTSLPGTSSLTPASPTLMTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTTTPTPASPTLMTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSTPTPAFSTLLTTTTPAQTTTVPGTSTPTPASSTLMTTSTPAETTSFPTTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAHTTSVPGTSYPNPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAQTTSVPATSTPTLASSALPTTSTPAQTTSVPGTSSPTPASSALPRTMTPAQTTLMQGTSSPSPATSAPPTTSTPAQTTSFHGTSTPTPASSTLPTTSTPAQTTSVPATSRPTPASSTLLTTSTPAETKTSLQLNSSPTSLSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSVPGTSSPTPASSAHRSTSTPAETTSVPGTSSPTPASSTLLTTTTPAQITSVPATSTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSAPPTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSLPGTSSPTSASSALPTTTTPAQTTTVPATSSPTPASSALPTTSTPAQTTSVKVTSSPTPASSTPMTTSTPAETKTSLLLNSSPKSVSSALLTTSTPAQTTSVPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPATSSRTPASSVLPTTTTPSQTTSVPGTSSATPASSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTTTTPAETKTSLQFNSSPTYASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLPTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTPVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSSHRSISTPAETTPVPGTSSPTPASSTLLTTTTPTQITSVPATSTRTPSSSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPGTSSPTPASSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGSTTPTPASSTLMTTSSLAQTTSLPRTSTPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTASMPGISSPTPASSALLTKSTPAQTTTVPGTSSPSPASSALPTTSTPARRTSFPATSSPTPASSALPTTSTPAQTTSVPATLTPNTASSTLMTTSTPAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTTTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRV", "length": 4128, "header": "tr|A0A8V1AGN9-1|A0A8V1AGN9_CHICK Isoform 1 of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A924-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1A924-1", "sequence": { "sequence": "MITSTPAQTTSVPGTSSPSPASSTPTTTRNPAQTTLLPGTSTPTPASSAPPTTSTPAQTTSVPATLTPNTASSTLMTASTLAQTTSLPGTSSRTPASSAPPTTRTPAQTKSSLQLNSSPTSISSALSTTTTPAQTTSVPGTSSPTPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAHTTSVPGTSYPNPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAQTTSVPATSTPTLASSALPTTSTPAQTTSVPGTSSPTPASSALPRTMTPAQTTLMQGTSSPSPATSAPPTTSTPAQTTSFHGTSTPTPASSTLPTTSTPAQTTSVPATSRPTPASSTLLTTSTPAETKTSLQLNSSPTSLSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSVPVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRV", "length": 1668, "header": "tr|A0A8V1A924-1|A0A8V1A924_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2331889, "end_pos": 2317112, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069022.1", "url": "https://www.ensembl.org/id/ENSGALT00010069022.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042464.1", "url": "https://www.ensembl.org/id/ENSGALP00010042464.1" } ] } }, { "isoform_ac": "A0A8V1A929-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1A929-1", "sequence": { "sequence": "MPTPAYSTLQTTSTPAVTTSVPGTSRPTPASSAPSTTRTPAQTKASLQLNSNPTSVSSSLPTTTTPAHTTTVPGTSSPTPASFTVLTTSTPSQTTSVPGTSSPTPASFTVLTTSTPSQTTSVPGTSSPTPASSALTTTSTPAQTTKVPATSTPTPASSTLMITSTPAQTTSVPGTSSPSPASSTPTTTRNPAQTTLLPGTSSPSPASSALLTTSTPAQTTSVPGTSSPTPASSVLPTTSTSAQTTSVPGISSPTPASSALPTATTPTQTTTVPGTSSPSPASSTPRTTRNPAQTTSVPGTSSPTPASSAPPTTSTPGETTSVPGTSTPTTASSTLQTTSTPAETTSLPATSTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSAPPTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSLPGTSSPTSASSALPTTTTPAQTTTVPATSSPTPASSALPTTSTPAQTTSVKVTSSPTPASSTPMTTSTPAETKTSLLLNSSPKSVSSALLTTSTPAQTTSVPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPATSSRTPASSVLPTTTTPSQTTSVPGTSSATPASSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTTTTPAETKTSLQFNSSPTYASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLPTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTPVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSSHRSISTPAETTPVPGTSSPTPASSTLLTTTTPTQITSVPATSTRTPSSSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPGTSSPTPASSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGSTTPTPASSTLMTTSSLAQTTSLPRTSTPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTASMPGISSPTPASSALLTKSTPAQTTTVPGTSSPSPASSALPTTSTPARRTSFPATSSPTPASSALPTTSTPAQTTSVPATLTPNTASSTLMTTSTPAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTTTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGNNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITHLGPYSLDRTSLYVNGYNEQPVTQPAMPTPTRPPTTPAGHERFTVNFTITNLPYDSDLQI", "length": 3853, "header": "tr|A0A8V1A929-1|A0A8V1A929_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2346757, "end_pos": 2315878, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069027.1", "url": "https://www.ensembl.org/id/ENSGALT00010069027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042469.1", "url": "https://www.ensembl.org/id/ENSGALP00010042469.1" } ] } }, { "isoform_ac": "A0A8V1AE66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AE66-1", "sequence": { "sequence": "MTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNDYSEPRDLSLEKPFNTQTPGQIIQQFTVNFTITNLRFTTDLGRSHSAKFNSTKKIMQHYIDPLLQKSSIGPDFIGCKVILFRSVTNSDSTAVDSICSYGNGSQVPNFDKATVYQELKNMTNNITKLGIYKLDKESLYVNGYNKPLQRSHLSITTAPSPTTSHFTLNFTLTNFQYTADLDAPNSRRFISTEKVIKHYIDPLFKRSSIRSVYTGCKVMGFRSGRHRSDTGVNAVCSYKNNGSMARFDRETVYHELSTMTNGVTKLGHFSLEKNSLYVNGFHLPDTATTRKPVLNKAPAITGYKLSFRIVNENLTNPDSQSPEYKAALESISKKLNQLYRQSNLQGQFLNCSITRLRVGSIVVDCNCFFQQEPSINRVEVEKAFQNGTSNTTGLWLGSSYQLQEFSVDGTYSSNLSCPVSTQFNPLPQNPPFSSLTQGKVYY", "length": 523, "header": "tr|A0A8V1AE66-1|A0A8V1AE66_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2301871, "end_pos": 2295970, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069019.1", "url": "https://www.ensembl.org/id/ENSGALT00010069019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042461.1", "url": "https://www.ensembl.org/id/ENSGALP00010042461.1" } ] } }, { "isoform_ac": "A0A8V1AE71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AE71-1", "sequence": { "sequence": "MTTSTLAQTTSLPGTSTPTPASSTLRIKSTPSETKTTLLLNSSPTSVSSALPTTSTPAHTTTVPGTSTPTPASSALPTTSTPAQTTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSTPTPAFSTLLTTTTPAQTTTVPGTSTPTPASSTLMTTSTPAETTSFPTTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAHTTSVPGTSYPNPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAQTTSVPATSTPTLASSALPTTSTPAQTTSVPGTSSPTPASSALPRTMTPAQTTLMQGTSSPSPATSAPPTTSTPAQTTSFHGTSTPTPASSTLPTTSTPAQTTSVPATSRPTPASSTLLTTSTPAETKTSLQLNSSPTSLSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSVPVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLVGNPQRCQGQDSLPLGLE", "length": 1688, "header": "tr|A0A8V1AE71-1|A0A8V1AE71_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2340163, "end_pos": 2317046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069024.1", "url": "https://www.ensembl.org/id/ENSGALT00010069024.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042466.1", "url": "https://www.ensembl.org/id/ENSGALP00010042466.1" } ] } }, { "isoform_ac": "A0A8V1AGN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AGN9-1", "sequence": { "sequence": "MITSTPAQTTSVPGTSSPSPASSTPTTTRNPAQTTLLPGTSTPTPASSAPPTTSTPAQTTSVPATLTPNTASSTLMTASTLAQTTSLPGTSSRTPASSAPPTTRTPAQTKSSLQLNSSPTSISSALSTTTTPAQTTSVPGTSSPNTASSALLTTTTPAQTTSVPGTSSPNTASSALLTTSTPAQTTTVPATSTPTPASSALPTTSTPAQRTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSTPTRASSTLMTRSTLAQTTSLPGTSSLTPASPTLMTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTTTPTPASPTLMTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSTPTPAFSTLLTTTTPAQTTTVPGTSTPTPASSTLMTTSTPAETTSFPTTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAHTTSVPGTSYPNPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAQTTSVPATSTPTLASSALPTTSTPAQTTSVPGTSSPTPASSALPRTMTPAQTTLMQGTSSPSPATSAPPTTSTPAQTTSFHGTSTPTPASSTLPTTSTPAQTTSVPATSRPTPASSTLLTTSTPAETKTSLQLNSSPTSLSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSVPGTSSPTPASSAHRSTSTPAETTSVPGTSSPTPASSTLLTTTTPAQITSVPATSTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSAPPTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSLPGTSSPTSASSALPTTTTPAQTTTVPATSSPTPASSALPTTSTPAQTTSVKVTSSPTPASSTPMTTSTPAETKTSLLLNSSPKSVSSALLTTSTPAQTTSVPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPATSSRTPASSVLPTTTTPSQTTSVPGTSSATPASSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTTTTPAETKTSLQFNSSPTYASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLPTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTPVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSSHRSISTPAETTPVPGTSSPTPASSTLLTTTTPTQITSVPATSTRTPSSSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPGTSSPTPASSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGSTTPTPASSTLMTTSSLAQTTSLPRTSTPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTASMPGISSPTPASSALLTKSTPAQTTTVPGTSSPSPASSALPTTSTPARRTSFPATSSPTPASSALPTTSTPAQTTSVPATLTPNTASSTLMTTSTPAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTTTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRV", "length": 4128, "header": "tr|A0A8V1AGN9-1|A0A8V1AGN9_CHICK Isoform 1 of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2331889, "end_pos": 2317112, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069021.1", "url": "https://www.ensembl.org/id/ENSGALT00010069021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042463.1", "url": "https://www.ensembl.org/id/ENSGALP00010042463.1" } ] } }, { "isoform_ac": "A0A8V1AGP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AGP4-1", "sequence": { "sequence": "MTASTLAQTTSLPGTSSRTPASSAPPTTRTPAQTKSSLQLNSSPTSISSALSTTTTPAQTTSVPGTSSPNTASSALLTTTTPAQTTSVPGTSSPNTASSALLTTSTPAQTTTVPATSTPTPASSALPTTSTPAQRTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSTPTRASSTLMTRSTLAQTTSLPGTSSLTPASPTLMTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTTTPTPASPTLMTTSTLAQTTSLPATSTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSAPPTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSLPGTSSPTSASSALPTTTTPAQTTTVPATSSPTPASSALPTTSTPAQTTSVKVTSSPTPASSTPMTTSTPAETKTSLLLNSSPKSVSSALLTTSTPAQTTSVPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGNNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGNNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAIT", "length": 2364, "header": "tr|A0A8V1AGP4-1|A0A8V1AGP4_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2331664, "end_pos": 2304978, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069026.1", "url": "https://www.ensembl.org/id/ENSGALT00010069026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042468.1", "url": "https://www.ensembl.org/id/ENSGALP00010042468.1" } ] } }, { "isoform_ac": "A0A8V1AIX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AIX5-1", "sequence": { "sequence": "MITSTPAQTTSVPGTSSPSPASSTPTTTRNPAQTTLLPGTSTPTPASSAPPTTSTPAQTTSVPATLTPNTASSTLMTASTLAQTTSLPGTSSRTPASSAPPTTRTPAQTKSSLQLNSSPTSISSALSTTTTPAQTTSVPGTSSPNTASSALLTTTTPAQTTSVPGTSSPNTASSALLTTSTPAQTTTVPATSTPTPASSALPTTSTPAQRTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSTPTRASSTLMTRSTLAQTTSLPGTSSLTPASPTLMTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTTTPTPASPTLMTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSTPTPAFSTLLTTTTPAQTTTVPGTSTPTPASSTLMTTSTPAETTSFPTTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAHTTSVPGTSYPNPASSTLMTTSTPAETKASLQLTSSPTSVSSTLPTSTTPAQTTSVPATSTPTLASSALPTTSTPAQTTSVPGTSSPTPASSALPRTMTPAQTTLMQGTSSPSPATSAPPTTSTPAQTTSFHGTSTPTPASSTLPTTSTPAQTTSVPATSRPTPASSTLLTTSTPAETKTSLQLNSSPTSLSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSVPGTSSPTPASSAHRSTSTPAETTSVPGTSSPTPASSTLLTTTTPAQITSVPATSTPTPASSTLMTTSTLAQTTSLPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPATSSRTPASSVLPTTTTPSQTTSVPGTSSATPASSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTTTTPAETKTSLQFNSSPTYASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLPTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTPVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSSHRSISTPAETTPVPGTSSPTPASSTLLTTTTPTQITSVPATSTRTPSSSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPGTSSPTPASSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGSTTPTPASSTLMTTSSLAQTTSLPRTSTPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTASMPGISSPTPASSALLTKSTPAQTTTVPGTSSPSPASSALPTTSTPARRTSFPATSSPTPASSALPTTSTPAQTTSVPATLTPNTASSTLMTTSTPAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTTTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGNNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNG", "length": 3844, "header": "tr|A0A8V1AIX5-1|A0A8V1AIX5_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2331889, "end_pos": 2318900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069020.1", "url": "https://www.ensembl.org/id/ENSGALT00010069020.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042462.1", "url": "https://www.ensembl.org/id/ENSGALP00010042462.1" } ] } }, { "isoform_ac": "A0A8V1AIX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AIX9-1", "sequence": { "sequence": "MTTSTLAQTTSLPATSTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSAPPTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSLPGTSSPTSASSALPTTTTPAQTTTVPATSSPTPASSALPTTSTPAQTTSVKVTSSPTPASSTPMTTSTPAETKTSLLLNSSPKSVSSALLTTSTPAQTTSVPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPATSSRTPASSVLPTTTTPSQTTSVPGTSSATPASSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTTTTPAETKTSLQFNSSPTYASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLPTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTPVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSSHRSISTPAETTPVPGTSSPTPASSTLLTTTTPTQITSVPATSTRTPSSSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPGTSSPTPASSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGSTTPTPASSTLMTTSSLAQTTSLPRTSTPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTASMPGISSPTPASSALLTKSTPAQTTTVPGTSSPSPASSALPTTSTPARRTSFPATSSPTPASSALPTTSTPAQTTSVPATLTPNTASSTLMTTSTPAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTTTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRV", "length": 3248, "header": "tr|A0A8V1AIX9-1|A0A8V1AIX9_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2340163, "end_pos": 2317112, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069025.1", "url": "https://www.ensembl.org/id/ENSGALT00010069025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042467.1", "url": "https://www.ensembl.org/id/ENSGALP00010042467.1" } ] } }, { "isoform_ac": "A0A8V1AKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AKQ3-1", "sequence": { "sequence": "MITSTPAQTTSVPGTSSPSPASSTPTTTRNPAQTTLLPGTSTPTPASSAPPTTSTPAQTTSVPATLTPNTASSTLMTASTLAQTTSLPGTSSRTPASSAPPTTRTPAQTKSSLQLNSSPTSISSALSTTTTPAQTTSVPGTSSPNTASSALLTTTTPAQTTTVPATSTPTPASSALPTTSTPAQRTSVPGTSSPTPASNGPPTTSTPAQTTSLPGTSTPTRASSTLMTRSTLAQTTSLPGTSSLTPASPTLMTTSTPAQTTSLPGTSILTPASNGLPTTSTLAQTTSLPGTTTPTPASPTLMTTSTLAQTTSLPGTSSPTPASPTLMSTSTPAQTTSLPGTTTPTPASPTLMTTSTLAQTTSLPGTSSPTPASSALPTTSTPAQTTSVPGTSSPTPASNGPPTTSTPAQTTSLPATSTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSAPPTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSLPGTSSPTSASSALPTTTTPAQTTTVPATSSPTPASSALPTTSTPAQTTSVKVTSSPTPASSTPMTTSTPAETKTSLLLNSSPKSVSSALLTTSTPAQTTSVPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPATSSRTPASSVLPTTTTPSQTTSVPGTSSATPASSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTTTTPAETKTSLQFNSSPTYASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLPTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTPVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSSHRSISTPAETTPVPGTSSPTPASSTLLTTTTPTQITSVPATSTRTPSSSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTTVPGTSSPTPASSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGSTTPTPASSTLMTTSSLAQTTSLPRTSTPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTASMPGISSPTPASSALLTKSTPAQTTTVPGTSSPSPASSALPTTSTPARRTSFPATSSPTPASSALPTTSTPAQTTSVPATLTPNTASSTLMTTSTPAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTTTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTSTPAQTTSMQGTSSRSPATFAHPTTSTPAETTSVLGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDPDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQR", "length": 3648, "header": "tr|A0A8V1AKQ3-1|A0A8V1AKQ3_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2333620, "end_pos": 2317115, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069023.1", "url": "https://www.ensembl.org/id/ENSGALT00010069023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042465.1", "url": "https://www.ensembl.org/id/ENSGALP00010042465.1" } ] } }, { "isoform_ac": "A0A8V1AKQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGN9/entry#A0A8V1AKQ7-1", "sequence": { "sequence": "MTTSTHAERKTSLLLNSSPTSVSSALPTTTTPAQTTSVPGTSTPTPAYSTLQTTSTPAQTTSVPGTSSPTPASSALPTTSTPAQTTTVPATTTPTPASSTLMITSTPAQTTSVPGTSSPSPASSTPTTTRNSAQTTLFPGTSSPTPASSALLTTSTPAQTTSVPATLTPNTASSTLMTASTLAQITSLPGTSSPTPASSAPSTTRTPAQTTSVPGTSSPTPASSALPTTSTPAQRTSVPATSTPTPASSTLMITSTPAQTTSVPGTSSPSPASSTLTTTRNPAQTTLLPGTSSPTPASSAPPTTSTPAQTTSVPATLTPNTASSTLMTASTLAQTTSLPGTSSPTPASSTLLTTSTPAQTTVPGTSTPTPASSALPTTSTPAQRTSVPATSTPTPAYSILMTTITPAETKTSLLLNSRPTSVSSALPTTTNPAQTTTVPATSTPTPASSALPTATTPAQTTTVPGTSSPTPASSTPTTTGNPAQTTLLPGTSSPTPASSAPPTTSTPAQTTSVPATLTPNTASSTLMTASTPAQTTSLPGTSSPTPASLVLPTTSTSAQTTSVPGISSPTPASSALPTATTPTQTTTVPGISSPTPASSALPTATTPTQTTTVPGTSSPSPASSTPRTTRNPAQTTSVPGTSSPTPASSAPPTTSTPGETTSVPGTSTPTTASSTLQTTSTPAETTSLPATSTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSAPPTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAQTTSLPATSSPTPATSTLMTTSIHAQRTSLPVTSSPTPASSSLITTSTPAETKTSLLLNSSPTSVSSALPTTTTPAQTTSLPGTSSPTSASSALPTTTTPAQTTTVPATSSPTPASSALPTTSTPAQTTSVKVTSSPTPASSTPMTTSTPAETKTSLLLNSSPKSVSSALLTTSTPAQTTSVPATSIPTPASSALPTTTTPAETTSVPVTSSPTPASNGLTTTSTPALTTSLPGTTTPTPASSTLMTTSSLAQTTSLPGTSTPTPASSTLMTLSTLAQTTSLPGTSTPTPASSTLMTTSTPAETKTSLQFNSSPTSASSALPTTTTPAQTTTVPGTSSPTPGSSALPTTTTPAETTTFPATSSTTPASSAPPTTSTPAQTTSLPGTTTPTPASSTLMTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGKSSPTPASSALTTTSTPAQTTSVPGTSTATPASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKPSLQLNSSPTSVSSALLTTSTPAQTTSFPATSSPTPAASTLMSTSTPAQTTTVPGTSSPTPASSALPTATTPAQTTTVPGTSSPTRVSSALLTTSTPAQITSVPATSTPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTTTPAQTTSVPGTSSPTPASSAHRSISTPAETTPVPGTSSPTPASSTLLTTTTPAQITSVPATSTRTPASSALPTTSTPAQTTSVQVTSSPTPASSTLMTTSTLAQTTSLPGTSTPTPASSTLMTTSTPAQTSLMPGTSSPTPASSALTTTSTPAQTTSVPASSSPTPASSALPTATTPAQTTAMPVTSSPTPASNGLPTTSTPAQTTTVTGTSSPTPASSALPTTTTPEQTTTVPGTSTPTPASSTVLTTSTPVQTTSMPGISSPTPASSALLTKSTPAQTTTVPATSSPTPASSALPTTTTPEQTTTESGTSTPTPASSGPPTTSTPAETTSVPGTSYPNPASSSLMTTSTLAQTTSLPATSTPSLASSTLMTKSTFAPTTALPGTSTPTPASSAPPTTSTPAQTTSVPGTSTATSASSTLLTTSTPAQTTSLPGTSSPTPASSAPLTTRTPAQTKASLQLNSSPTSVSSARLTTSTPAQTTSFPATSSPTPASSTLMTTSTPAQTTTVPGTSSPTPVSSALLTTRTLAQTKASLQLNSSPTSVSSALPTTSTPAETTTVPGTSIPTAASSTLLTTSTLAQTTSFPATSTPTPSSSTLMTTSTRAETKTSLQLNSSPTPASSALSTTSTPALTTALRSTSQIMSPSSPATSPSPTATSAGTVTTAQETTSPAGTTNALTSTIRTTSTQTLSSSSPPYTTAAPSYTAIPTSTPATPTTSAPQTTIASSSTPTESTALLTTTVPSTTQDISSQTAQTSNAATSSTTNSATSARLTRTHAETTSSTTTFTSHSRPSASQTSTPGTTISPLPATTAQQTTAPAGTTPPTTASTTLFSTRETSSKEEETSTVVTSSQTPASSVLPSTSTPAQTTSMPSTSSPTPASSTLMTTSTLAQTTSLPGTSVPTPASSAPRTTTTPAQTTSVPGNSSPIPPYSTLLTTSTLAQTTSLPGTSSPTPASSALTTTSTPAQTKTSLQLNSSPTSVSSALLTTTSPAQTKSQPGTSSPTSALLTSTHAESKPSITTFTSRARTSASWTTTPGTTTSALTATTARETTTPAGTTHPHNSNIETTSTSTIKAPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGRERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITHLGPYSLDRTSLYVNGYNEQPVTQPAMPTPTRPPTTPAGHERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGNNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGYNEQPVTQPATPTPTRPPTTPAGHERFTVNFTITNLPYDSDLQIPHSAKLNATQRVMTTLLNRLLKDTSIGPSFLGCATTAFRSVRQGDNTGVDLVCTYRKEPSSPDLDRVGLYHEVSNKTSAITRLGPYSLDRTSLYVNGEFFFFFPSFFVAFLIFF", "length": 3104, "header": "tr|A0A8V1AKQ7-1|A0A8V1AKQ7_CHICK Computationally mapped isoform of SEA domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGN9-1" }, "locus": { "chromosome": "28", "start_pos": 2346883, "end_pos": 2301069, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069028.1", "url": "https://www.ensembl.org/id/ENSGALT00010069028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042470.1", "url": "https://www.ensembl.org/id/ENSGALP00010042470.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1000, "start_aa": "Thr", "end_pos": 1000, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1000", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1076, "start_aa": "Thr", "end_pos": 1076, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1076", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1087, "start_aa": "Thr", "end_pos": 1087, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1087", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1101, "start_aa": "Thr", "end_pos": 1101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1101", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1177, "start_aa": "Thr", "end_pos": 1177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1177", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1202, "start_aa": "Thr", "end_pos": 1202, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1202", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1227, "start_aa": "Thr", "end_pos": 1227, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1227", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1252, "start_aa": "Thr", "end_pos": 1252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1252", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1302, "start_aa": "Thr", "end_pos": 1302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1302", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1338, "start_aa": "Thr", "end_pos": 1338, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1338", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1352, "start_aa": "Thr", "end_pos": 1352, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1352", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1403, "start_aa": "Thr", "end_pos": 1403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1403", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1439, "start_aa": "Thr", "end_pos": 1439, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1439", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1453, "start_aa": "Thr", "end_pos": 1453, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1453", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", 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"id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "Golgi cisterna", "id": "GO:0031985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031985", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "phagosome-lysosome fusion", "id": "GO:0090385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090385", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" }, { "name": "antigen processing and presentation", "id": "GO:0019882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", 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"gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] } ] }, { "uniprot_ac": "A0A8V0YGN8", "gene_name": "RAB21", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] } ] }, { "uniprot_ac": "A0A8V0YHK2", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] } ] }, { "uniprot_ac": "A0A8V0YIM0", "gene_name": 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Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418222.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418222" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM259", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7", "locus": { "chromosome": "28", "start_pos": 3326673, "end_pos": 3336799, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027972", "url": "https://www.ensembl.org/id/ENSGALG00010027972" } ] } } ], "crossref": [ { "id": "A0A8V1AGP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "420101", "url": "https://www.ncbi.nlm.nih.gov/gene/420101", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGP7", "url": "https://www.orthodb.org/?gene=A0A8V1AGP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21650", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21650", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21650:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21650:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418222", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEAQPHGQHPPPNHTGAAGGTNRAGRNAALNQNPLINVRDRLFHALFFKMAVTYARLFPPSFRRVFEFFVLLKALFVLFILAYIHIAFSRSPINCLEHVRDKWPRDGILRVEIQRNSSRAPIFLQFCGAEKFPGMVVEPTAEEEEEEEEEMSVDMFENSSIKFELDIEPKVFLKPSRMSSTEALAHNESQEFSFSEAATKVWPQEEYIVEYSLEYGFLRLSQSTRQRLSIPVMVVTLDPTRDQCFGDRFSRLLLDEFLGYDDILMSSVKALAENEENKGFLRNVVSGEHYRFVSMWMARTSYLAAFVIMVIFTLSVSMLLRYSHHQIFVFIVDLLQMLEMNMTIAFPAAPLLTVILALVGMEAIMSEFFNDTTTAFYIILIVWLADQYDAICCHTNTSKRHWLRFFYLYHFAFYAYHYRFNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILRQIRIQEMLLQNQQVGQGTQTTLQDNLNNNTTPAGAEVGGHRPHLAAGPSGESSSPAALASSEASSVIATAAASSVGSDLNWVAETAAIVTEASFLSDLSSSLLEPNVVHEAVAAGSPQDAAAASGLVARIRVSSDHPDTAVGSITIEVTSAPVVAAADGPPAAEVAAAPPPIPIQEDGASTPSPSPAEQTEAVESSDSQAKPSGKNCIANGSVAESPLAFVENTDQDKLLGCALGDRGESGPCPAPADSTASSRPCSEPDLRSLS", "length": 720, "header": "tr|A0A8V1AGP7-1|A0A8V1AGP7_CHICK Isoform 1 of Transmembrane protein 259 OS=Gallus gallus OX=9031 GN=TMEM259 PE=4 SV=1 CANONICAL=A0A8V1AGP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7/entry#A0A8V1AGP7-1", "sequence": { "sequence": "MSEAQPHGQHPPPNHTGAAGGTNRAGRNAALNQNPLINVRDRLFHALFFKMAVTYARLFPPSFRRVFEFFVLLKALFVLFILAYIHIAFSRSPINCLEHVRDKWPRDGILRVEIQRNSSRAPIFLQFCGAEKFPGMVVEPTAEEEEEEEEEMSVDMFENSSIKFELDIEPKVFLKPSRMSSTEALAHNESQEFSFSEAATKVWPQEEYIVEYSLEYGFLRLSQSTRQRLSIPVMVVTLDPTRDQCFGDRFSRLLLDEFLGYDDILMSSVKALAENEENKGFLRNVVSGEHYRFVSMWMARTSYLAAFVIMVIFTLSVSMLLRYSHHQIFVFIVDLLQMLEMNMTIAFPAAPLLTVILALVGMEAIMSEFFNDTTTAFYIILIVWLADQYDAICCHTNTSKRHWLRFFYLYHFAFYAYHYRFNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILRQIRIQEMLLQNQQVGQGTQTTLQDNLNNNTTPAGAEVGGHRPHLAAGPSGESSSPAALASSEASSVIATAAASSVGSDLNWVAETAAIVTEASFLSDLSSSLLEPNVVHEAVAAGSPQDAAAASGLVARIRVSSDHPDTAVGSITIEVTSAPVVAAADGPPAAEVAAAPPPIPIQEDGASTPSPSPAEQTEAVESSDSQAKPSGKNCIANGSVAESPLAFVENTDQDKLLGCALGDRGESGPCPAPADSTASSRPCSEPDLRSLS", "length": 720, "header": "tr|A0A8V1AGP7-1|A0A8V1AGP7_CHICK Isoform 1 of Transmembrane protein 259 OS=Gallus gallus OX=9031 GN=TMEM259 PE=4 SV=1 CANONICAL=A0A8V1AGP7-1" }, "locus": { "chromosome": "28", "start_pos": 3336480, "end_pos": 3327094, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067787.1", "url": "https://www.ensembl.org/id/ENSGALT00010067787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041530.1", "url": "https://www.ensembl.org/id/ENSGALP00010041530.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7" } ], "pmid": "" }, { "name": "positive regulation of ERAD pathway", "id": "GO:1904294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904294", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 14, "end_pos": 16 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 665, "end_pos": 667 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGP8-1", "uniprot_ac": "A0A8V1AGP8", "uniprot_id": "A0A8V1AGP8_CHICK", "mass": { "chemical_mass": 17659.0, "monoisotopic_mass": 17659.0 }, "refseq": { "ac": "XP_024997856", "name": "60S ribosomal protein L23a isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997856" }, "gene_names": [ { "name": "RPL23A", "type": "recommended", "evidence": [ { "id": "A0A8V1AGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ] }, { "name": "RPL23A", "type": "synonym", "evidence": [ { "id": "XP_024997856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997856" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL23", "type": "recommended", "evidence": [ { "id": "A0A8V1AGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L23a isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024997856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997856" } ] }, { "name": "60S ribosomal protein L23a", "type": "synonym", "evidence": [ { "id": "A0A8V1AGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997856" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ABE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABE3#function" }, { "database": "UniProtKB", "id": "ARBA00045456", "url": "https://www.uniprot.org/uniprotkb/ARBA00045456#function" }, { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8#function" }, { "database": "UniProtKB", "id": "A0A8V1AIT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL23A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8", "locus": { "chromosome": "19", "start_pos": 6289428, "end_pos": 6286719, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029218", "url": "https://www.ensembl.org/id/ENSGALG00010029218" } ] } } ], "crossref": [ { "id": "A0A8V1AGP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "417574", "url": "https://www.ncbi.nlm.nih.gov/gene/417574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417574", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RLDHHKV", "url": "https://omabrowser.org/oma/group/RLDHHKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABE3", "url": "https://www.orthodb.org/?gene=A0A8V1ABE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGP8", "url": "https://www.orthodb.org/?gene=A0A8V1AGP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIT2", "url": "https://www.orthodb.org/?gene=A0A8V1AIT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00276", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00276", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKAKKEAVPPKTEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKVSNV", "length": 155, "header": "tr|A0A8V1AGP8-1|A0A8V1AGP8_CHICK Isoform 1 of Large ribosomal subunit protein uL23 OS=Gallus gallus OX=9031 GN=RPL23A PE=1 SV=1 CANONICAL=A0A8V1AGP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8/entry#A0A8V1ABE3-1", "sequence": { "sequence": "AVPPKTEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 147, "header": "tr|A0A8V1ABE3-1|A0A8V1ABE3_CHICK Computationally mapped isoform of Large ribosomal subunit protein uL23 OS=Gallus gallus OX=9031 GN=RPL23A PE=1 SV=1 CANONICAL=A0A8V1AGP8-1" }, "locus": { "chromosome": "19", "start_pos": 6289062, "end_pos": 6286965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070605.1", "url": "https://www.ensembl.org/id/ENSGALT00010070605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043296.1", "url": "https://www.ensembl.org/id/ENSGALP00010043296.1" } ] } }, { "isoform_ac": "A0A8V1AGP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8/entry#A0A8V1AGP8-1", "sequence": { "sequence": "MAPKAKKEAVPPKTEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKVSNV", "length": 155, "header": "tr|A0A8V1AGP8-1|A0A8V1AGP8_CHICK Isoform 1 of Large ribosomal subunit protein uL23 OS=Gallus gallus OX=9031 GN=RPL23A PE=1 SV=1 CANONICAL=A0A8V1AGP8-1" }, "locus": { "chromosome": "19", "start_pos": 6288357, "end_pos": 6286745, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070607.1", "url": "https://www.ensembl.org/id/ENSGALT00010070607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043298.1", "url": "https://www.ensembl.org/id/ENSGALP00010043298.1" } ] } }, { "isoform_ac": "A0A8V1AIT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8/entry#A0A8V1AIT2-1", "sequence": { "sequence": "MAPKAKKEAVPPKTEAKAKALKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 148, "header": "tr|A0A8V1AIT2-1|A0A8V1AIT2_CHICK Computationally mapped isoform of Large ribosomal subunit protein uL23 OS=Gallus gallus OX=9031 GN=RPL23A PE=1 SV=1 CANONICAL=A0A8V1AGP8-1" }, "locus": { "chromosome": "19", "start_pos": 6289062, "end_pos": 6286745, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070609.1", "url": "https://www.ensembl.org/id/ENSGALT00010070609.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043300.1", "url": "https://www.ensembl.org/id/ENSGALP00010043300.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417574", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417574", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7GLT3-1", "protein_name": "Large ribosomal subunit protein uL23", "gene_name": "Rpl23a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 156 }, "evidence": [ { "id": "A0A8V1AGP8", "url": "https://omabrowser.org/oma/group/A0A8V1AGP8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LT35-1", "protein_name": "Large ribosomal subunit protein uL23", "gene_name": "Rpl23al1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGIFQLWRLKQDGHLKPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 171 }, "evidence": [ { "id": "A0A8V1AGP8", "url": "https://omabrowser.org/oma/group/A0A8V1AGP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P04456-1", "protein_name": "Large ribosomal subunit protein uL23", "gene_name": "RPL25", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAPSAKATAAKKAVVKGTNGKKALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSETAMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKKAYVRLTADYDALDIANRIGYI", "length": 142 }, "evidence": [ { "id": "A0A8V1AGP8", "url": "https://omabrowser.org/oma/group/A0A8V1AGP8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P62750-1", "protein_name": "Large ribosomal subunit protein uL23", "gene_name": "RPL23A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 156 }, "evidence": [ { "id": "A0A8V1AGP8", "url": "https://omabrowser.org/oma/group/A0A8V1AGP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62751-1", "protein_name": "Large ribosomal subunit protein uL23", "gene_name": "Rpl23a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 156 }, "evidence": [ { "id": "A0A8V1AGP8", "url": "https://omabrowser.org/oma/group/A0A8V1AGP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" }, { "name": "cytosolic large ribosomal subunit", "id": "GO:0022625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" }, { "name": "ribosomal subunit", "id": "GO:0044391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" }, { "name": "TORC2 complex binding", "id": "GO:1904841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGP8" }, { "id": "PF03939", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03939" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL23 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 66, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGS0-1", "uniprot_ac": "A0A8V1AGS0", "uniprot_id": "A0A8V1AGS0_CHICK", "mass": { "chemical_mass": 9521.0, "monoisotopic_mass": 9521.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AGS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS0", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AGS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLGFAICPSHTEVVLMPALAWQNWLIWCTMLLRSGGWFCCRVAAIERGMVEVDTVTFGGASASGIFLLPCKPGCSKGFGGGCSAWCAMV", "length": 90, "header": "tr|A0A8V1AGS0-1|A0A8V1AGS0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGS0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS0/entry#A0A8V1AGS0-1", "sequence": { "sequence": "MGLGFAICPSHTEVVLMPALAWQNWLIWCTMLLRSGGWFCCRVAAIERGMVEVDTVTFGGASASGIFLLPCKPGCSKGFGGGCSAWCAMV", "length": 90, "header": "tr|A0A8V1AGS0-1|A0A8V1AGS0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGS0-1" }, "locus": { "chromosome": "19", "start_pos": 6316510, "end_pos": 6316241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070634.1", "url": "https://www.ensembl.org/id/ENSGALT00010070634.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043325.1", "url": "https://www.ensembl.org/id/ENSGALP00010043325.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGS5-1", "uniprot_ac": "A0A8V1AGS5", "uniprot_id": "A0A8V1AGS5_CHICK", "mass": { "chemical_mass": 56949.0, "monoisotopic_mass": 56949.0 }, "refseq": {}, "gene_names": [ { "name": "UTP18", "type": "recommended", "evidence": [ { "id": "A0A8V1AGS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5" } ] } ], "protein_names": [ { "name": "U3 small nucleolar RNA-associated protein 18 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V1AGS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 50", "type": "synonym", "evidence": [ { "id": "A0A8V1AGS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5#function" }, { "database": "UniProtKB", "id": "ARBA00058527", "url": "https://www.uniprot.org/uniprotkb/ARBA00058527#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UTP18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5", "locus": { "chromosome": "18", "start_pos": 5732163, "end_pos": 5721781, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029227", "url": "https://www.ensembl.org/id/ENSGALG00010029227" } ] } } ], "crossref": [ { "id": "A0A8V1AGS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGS5", "url": "https://www.orthodb.org/?gene=A0A8V1AGS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18359:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18359:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKRARPRAKEMEAAAAEASRRARHLRAISDATAAERELEELVFGDSLVAEEGELLQRLAGPQVSAARSGALPCRSSDSESENEAKGGLSSKGPAWVDEDDEAEERIDMTHRYRRELMKSDAEKILTKKKLKARLEEQFQRAMGGVPAWADRENRKKYKQAASDSGSDEDDDLLCRTGNFVSSSESLPRGILEMKSCLPANQERLADGKLSTVQFHPSAQVVLTAGRDRSVSLFQVDGIRNPKIQSIYLESFPIYKARFSADGEQVIATGTHHKVFYVYDMMGGSIIPVHQVRGMEEKFVKNFEVSPDGSFMLLTGTSGYLHLLSMKTKELISTMKVNGRTTACAFTSDSSKIYSYSKEGEVFIWDVRSRKCLHKFEDEGSLEGKCIAVSKNNQYVACGSVSGVVNLYTTDVCLKENHPKPVKAIMNLVTSATSVTFNPTTEILAVASNEADEAVKLIHIPSYTVFSNFPVFRRKQIYLTQSMDFSPRSGFFSIANNKGKALLYRLKHYSDF", "length": 512, "header": "tr|A0A8V1AGS5-1|A0A8V1AGS5_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 18 homolog OS=Gallus gallus OX=9031 GN=UTP18 PE=1 SV=1 CANONICAL=A0A8V1AGS5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5/entry#A0A8V1AGS5-1", "sequence": { "sequence": "MVKRARPRAKEMEAAAAEASRRARHLRAISDATAAERELEELVFGDSLVAEEGELLQRLAGPQVSAARSGALPCRSSDSESENEAKGGLSSKGPAWVDEDDEAEERIDMTHRYRRELMKSDAEKILTKKKLKARLEEQFQRAMGGVPAWADRENRKKYKQAASDSGSDEDDDLLCRTGNFVSSSESLPRGILEMKSCLPANQERLADGKLSTVQFHPSAQVVLTAGRDRSVSLFQVDGIRNPKIQSIYLESFPIYKARFSADGEQVIATGTHHKVFYVYDMMGGSIIPVHQVRGMEEKFVKNFEVSPDGSFMLLTGTSGYLHLLSMKTKELISTMKVNGRTTACAFTSDSSKIYSYSKEGEVFIWDVRSRKCLHKFEDEGSLEGKCIAVSKNNQYVACGSVSGVVNLYTTDVCLKENHPKPVKAIMNLVTSATSVTFNPTTEILAVASNEADEAVKLIHIPSYTVFSNFPVFRRKQIYLTQSMDFSPRSGFFSIANNKGKALLYRLKHYSDF", "length": 512, "header": "tr|A0A8V1AGS5-1|A0A8V1AGS5_CHICK Isoform 1 of U3 small nucleolar RNA-associated protein 18 homolog OS=Gallus gallus OX=9031 GN=UTP18 PE=1 SV=1 CANONICAL=A0A8V1AGS5-1" }, "locus": { "chromosome": "18", "start_pos": 5729347, "end_pos": 5721871, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070639.1", "url": "https://www.ensembl.org/id/ENSGALT00010070639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043330.1", "url": "https://www.ensembl.org/id/ENSGALP00010043330.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Pwp2p-containing subcomplex of 90S preribosome", "id": "GO:0034388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGT0-1", "uniprot_ac": "A0A8V1AGT0", "uniprot_id": "A0A8V1AGT0_CHICK", "mass": { "chemical_mass": 55409.0, "monoisotopic_mass": 55409.0 }, "refseq": { "ac": "NP_001376620", "name": "chromobox protein homolog 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376620" }, "gene_names": [ { "name": "CBX2", "type": "recommended", "evidence": [ { "id": "A0A8V1AGT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ] }, { "name": "CBX2", "type": "synonym", "evidence": [ { "id": "NP_001376620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376620" } ] } ], "protein_names": [ { "name": "Chromobox 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AGT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0/entry#names_and_taxonomy" } ] }, { "name": "chromobox homolog 2 (Pc class homolog, Drosophila)", "type": "synonym", "evidence": [ { "id": "NP_001376620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376620" } ] }, { "name": "chromobox protein homolog 2", "type": "synonym", "evidence": [ { "id": "NP_001376620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376620" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267652.15537.1, SRR13267658.18197.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000317.1. On Sep 23, 2021 this sequence version replaced NP_001376620.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376620", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376620" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CBX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0", "locus": { "chromosome": "18", "start_pos": 10261398, "end_pos": 10268436, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029233", "url": "https://www.ensembl.org/id/ENSGALG00010029233" } ] } } ], "crossref": [ { "id": "A0A8V1AGT0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18647", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18647", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426248", "url": "https://www.ncbi.nlm.nih.gov/gene/426248", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NCGISWQ", "url": "https://omabrowser.org/oma/group/NCGISWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGT0", "url": "https://www.orthodb.org/?gene=A0A8V1AGT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46860:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46860:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4570464", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4570464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376620", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376620", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHVEPEMPSKSKSSSSSSSTSSSSSSSDEEDESDLEAKRGPRSRETHPVPQKKAQILVAKPEMKDSSRKKRGRKPLPPEQKAARRTVNLTKVLKTSRKEVGGSSKLLGKLQAQHGPQGTGLAGLKEPPGALAGLSSGGSSAENVPNAMKSGSSSPSRAISWQSSIVHYMNRMSQNQSSAETSPLGRLALKSQASSKSGLGLDLKMRNQKGAGELGLSMQGAKTAKVPSSSAGGDQKSGFTTGAQMLHNGSKTPTSSSVPGGQQASSQELNLQALNLQSVKNGQSAAGGSSVPRHACSTQPKSTSAAAGSGPAGSKGGGSGAGLNAASVGDGSKSEKQARRAGAGDRDVAKGGTGGGQEGHAAPESRKATALSEMSTGDESSSDSDRDSASFPGVGQNMSVSIQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNVRQY", "length": 528, "header": "tr|A0A8V1AGT0-1|A0A8V1AGT0_CHICK Isoform 1 of Chromobox 2 OS=Gallus gallus OX=9031 GN=CBX2 PE=4 SV=1 CANONICAL=A0A8V1AGT0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0/entry#A0A8V1AGT0-1", "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHVEPEMPSKSKSSSSSSSTSSSSSSSDEEDESDLEAKRGPRSRETHPVPQKKAQILVAKPEMKDSSRKKRGRKPLPPEQKAARRTVNLTKVLKTSRKEVGGSSKLLGKLQAQHGPQGTGLAGLKEPPGALAGLSSGGSSAENVPNAMKSGSSSPSRAISWQSSIVHYMNRMSQNQSSAETSPLGRLALKSQASSKSGLGLDLKMRNQKGAGELGLSMQGAKTAKVPSSSAGGDQKSGFTTGAQMLHNGSKTPTSSSVPGGQQASSQELNLQALNLQSVKNGQSAAGGSSVPRHACSTQPKSTSAAAGSGPAGSKGGGSGAGLNAASVGDGSKSEKQARRAGAGDRDVAKGGTGGGQEGHAAPESRKATALSEMSTGDESSSDSDRDSASFPGVGQNMSVSIQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNVRQY", "length": 528, "header": "tr|A0A8V1AGT0-1|A0A8V1AGT0_CHICK Isoform 1 of Chromobox 2 OS=Gallus gallus OX=9031 GN=CBX2 PE=4 SV=1 CANONICAL=A0A8V1AGT0-1" }, "locus": { "chromosome": "18", "start_pos": 10268335, "end_pos": 10264137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070649.1", "url": "https://www.ensembl.org/id/ENSGALT00010070649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043340.1", "url": "https://www.ensembl.org/id/ENSGALP00010043340.1" } ] } }, { "isoform_ac": "A0A8V1AL01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0/entry#A0A8V1AL01-1", "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKEHEKEVQNRKRGKRPRGRPRKHVEPEMPSKSKSSSSSSSTSSSSSSSDEEDESDLEAKRGPRSRETHPVPQKKAQILVAKPEMKDSSRKKRGRKPLPPEQKAARRTVNLTKVLKTSRKEVGGSSKLLGKLQAQHGPQGTGLAGLKEPPGALAGLSSGGSSAENVPNAMKSGSSSPSRAISWQSSIVHYMNRMSQNQSSAETSPLGRLALKSQASSKSGLGLDLKMRNQKGAGELGLSMQGAKTAKVPSSSAGGDQKSGFTTGAQMLHNGSKTPTSSSVPGGQQASSQELNLQALNLQSVKNGQSAAGGSSVPRHACSTQPKSTSAAAGSGPAGSKGGGSGAGLNAASVGDGSKSEKQARRAGAGDRDVAKGGTGGGQEGHAAPESRKATALSEMSTGDESSSDSDRDSASFPGVGQNMSVSIQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNVRQY", "length": 506, "header": "tr|A0A8V1AL01-1|A0A8V1AL01_CHICK Computationally mapped isoform of Chromobox 2 OS=Gallus gallus OX=9031 GN=CBX2 PE=4 SV=1 CANONICAL=A0A8V1AGT0-1" }, "locus": { "chromosome": "18", "start_pos": 10268335, "end_pos": 10264137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070650.1", "url": "https://www.ensembl.org/id/ENSGALT00010070650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043341.1", "url": "https://www.ensembl.org/id/ENSGALP00010043341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4570464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4570464", "resource": "Reactome", "description": "SUMOylation of RNA binding proteins" }, { "id": "R-GGA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LU16-1", "protein_name": "Chromobox 2", "gene_name": "CBX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEAQNRKRGKRPRGRPRKHTVMSSCSRHSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTARKDLGPPASKLPPPLSAPVAGLAALKAHAKEACSGPSSMATPENLASLMKGMAGSPSRGGISWQSSIMHYMNRMSQSQAQAAGRLALRAPTPGKCSLGLDLKVRTQKGELGISPPGGKGPKAPSSGAVEQKAGSTGGPSHVHSSSKVPAGCLGSQPPPTQELSLQVLDLQSVKNGTPGVGLVARHTTATKGIPATNPATGKSAGGGPTGGSGAGLPTDASKSEKLTSRAAALPTPAGKRDCAKGSTAPGQEGHPASGEARKTAALSEMSTGEENSSSDSDPDSGSLPSAGQNLSVSVQTSQDWKPPRSLIEHVFVTDVTANLITVTVKESPTSVGFFSLRHY", "length": 531 }, "evidence": [ { "id": "A0A8V1AGT0", "url": "https://omabrowser.org/oma/group/A0A8V1AGT0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RE14-1", "protein_name": "Chromobox 2", "gene_name": "Cbx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHTVMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEEEDDDDSDLDSKRGSRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTTRKDLVTSAPKLPPPLSAPVAGLAALKAHTKEACGGPSTMATPENLASLMKGMAGSPSRGGISWQSSIVHYMNRMSQSQAQAASRLALKAQAANKCSLGPDLKVRTQKGELGVNPAGSKVPKAPGSVAAEQQRGNNSGSPGSQLPPTQELSLQVLDLQSVKNGVPGVGLPARHATATKAIPATNTATGKGPGSGPTGVNVTNAPTDTSKGEKLTCKTAALPAPSVKRDAAKSIAASGGQEGHTVPGEGQKPPALCELSTGEENSSSDSDPDSSSLPSAGQNLSVAVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLKHY", "length": 523 }, "evidence": [ { "id": "A0A8V1AGT0", "url": "https://omabrowser.org/oma/group/A0A8V1AGT0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P30658-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "Cbx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHTVTSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEEDDSDLDSKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTTRKDLGTSAAKLPPPLSAPVAGLAALKAHTKEACGGPSTMATPENLASLMKGMAGSPSRGGIWQSSIVHYMNRMSQSQVQAASRLALKAQATNKCGLGLDLKVRTQKGGELGGSPAGGKVPKAPGGGAAEQQRGNHSGSPGAQLAPTQELSLQVLDLQSVKNGVPGVGLLARHAPAKAIPATNPATGKGPGSGPTGANMTNAPTDNNKGEKLTCKATALPAPSVKRDTVKSVAASGGQEGHTAPGEGRKPPALSELSTGEENSSSDSDPDSTSLPSAAQNLSVAIQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY", "length": 519 }, "evidence": [ { "id": "A0A8V1AGT0", "url": "https://omabrowser.org/oma/group/A0A8V1AGT0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKATRRPVSLAKVLKTARKDLGAPASKLPPPLSAPVAGLAALKAHAKEACGGPSAMATPENLASLMKGMASSPGRGGISWQSSIVHYMNRMTQSQAQAASRLALKAQATNKCGLGLDLKVRTQKGELGMSPPGSKIPKAPSGGAVEQKVGNTGGPPHTHGASRVPAGCPGPQPAPTQELSLQVLDLQSVKNGMPGVGLLARHATATKGVPATNPAPGKGTGSGLIGASGATMPTDTSKSEKLASRAVAPPTPASKRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY", "length": 532 }, "evidence": [ { "id": "A0A8V1AGT0", "url": "https://omabrowser.org/oma/group/A0A8V1AGT0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" }, { "name": "development of primary sexual characteristics", "id": "GO:0045137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045137", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT0" }, { "id": "PS50013", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 70, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 478, "end_pos": 480 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGT2-1", "uniprot_ac": "A0A8V1AGT2", "uniprot_id": "A0A8V1AGT2_CHICK", "mass": { "chemical_mass": 25097.0, "monoisotopic_mass": 25097.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AGT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT2", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR35001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35001:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35001:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACKGQARQGRARTGKARQVQARPRKARHGKTSPGHSRQGESRPGMAREFKASPGKAKKIQAKPGKARPGKARQCKASEGKARQGMARQVKARPRMARPGKARQGNSSPVTARQGKASQCMQSQARQGNARQVQGRPGKSRQGQAMQGKVRQVQARPGKARQVQASHGRARQGQSMQGKSRQVQARHTRQGKGKQGTQGEATQGKSRQDEAGPGKAMQVQASHGKTCQGQARPG", "length": 234, "header": "tr|A0A8V1AGT2-1|A0A8V1AGT2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT2/entry#A0A8V1AGT2-1", "sequence": { "sequence": "MACKGQARQGRARTGKARQVQARPRKARHGKTSPGHSRQGESRPGMAREFKASPGKAKKIQAKPGKARPGKARQCKASEGKARQGMARQVKARPRMARPGKARQGNSSPVTARQGKASQCMQSQARQGNARQVQGRPGKSRQGQAMQGKVRQVQARPGKARQVQASHGRARQGQSMQGKSRQVQARHTRQGKGKQGTQGEATQGKSRQDEAGPGKAMQVQASHGKTCQGQARPG", "length": 234, "header": "tr|A0A8V1AGT2-1|A0A8V1AGT2_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGT2-1" }, "locus": { "chromosome": "25", "start_pos": 305729, "end_pos": 304226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067822.1", "url": "https://www.ensembl.org/id/ENSGALT00010067822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041565.1", "url": "https://www.ensembl.org/id/ENSGALP00010041565.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGU2-1", "uniprot_ac": "A0A8V1AGU2", "uniprot_id": "A0A8V1AGU2_CHICK", "mass": { "chemical_mass": 148288.0, "monoisotopic_mass": 148288.0 }, "refseq": { "ac": "XP_046759928", "name": "pogo transposable element with ZNF domain isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759928" }, "gene_names": [ { "name": "POGZ", "type": "recommended", "evidence": [ { "id": "A0A8V1AGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ] }, { "name": "POGZ", "type": "synonym", "evidence": [ { "id": "XP_046759928", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759928" } ] } ], "protein_names": [ { "name": "Pogo transposable element with ZNF domain", "type": "recommended", "evidence": [ { "id": "A0A8V1AGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2/entry#names_and_taxonomy" } ] }, { "name": "pogo transposable element with ZNF domain isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046759928", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759928" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759928" } ] }, { "annotation": "Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. Promotes the repair of DNA double-strand breaks through the homologous recombination pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2#function" }, { "database": "UniProtKB", "id": "ARBA00056049", "url": "https://www.uniprot.org/uniprotkb/ARBA00056049#function" }, { "database": "UniProtKB", "id": "A0A8V1AEB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POGZ", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2", "locus": { "chromosome": "25", "start_pos": 2764355, "end_pos": 2737952, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027983", "url": "https://www.ensembl.org/id/ENSGALG00010027983" } ] } } ], "crossref": [ { "id": "429985", "url": "https://www.ncbi.nlm.nih.gov/gene/429985", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEB0", "url": "https://www.orthodb.org/?gene=A0A8V1AEB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGU2", "url": "https://www.orthodb.org/?gene=A0A8V1AGU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046759928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759928", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAAFWDREGLILLDFLGPGQTASSDRVVALTELKAPTSRMADTDLFMECEEEELEPWQKISDVIEDSVVEDYNSVDKTTTAGNPLVQQGGQPLILTQNPTSGLGTMVTQPVLRPVQIMQNANHVTNSPVTSQPIFITTQGFPVRNVRPVQNTMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPAVGVPQVFSQVAQVRPGTTMPVRPTTNTFTTVIPATLTIRSTVPQSQSQQQMSIASFVTVKRPGVTGENSNEVAKLVNTLNTVPSLGQSPGPMVVSNSSPVHGSQRSSTSESSSSSLKVSSSPIPTFDLQDGGRKVCPRCDAQFRVTEALRGHMCYCCPEMVEFLKKRKSLDSEPNIQSAKPPSPEKTTAVASPPSSTPIPALSPPAKAPEPNEGMVDSSQSKLIMLVDDFYYGRDGGKVSQLLNFPKVPTSFRCPHCTKRLKNNIRFMNHMKHHVELDQQNGEVDVHTICQHCYRQFSTPFQLQCHLENVHSPYESTTKCKICEWAFESEPMFLQHMKDTHKPGEMPYVCQVCQYRSSLYSEVDSHFRMIHEDTRHLLCPYCLKVFKNGNAFQQHFMRHQKKSVYHCNKCRLQFLFAKDKIEHKLQHHKTFRKPKQLEGLKPGTKVTIRASRGQPRTVPISSNDMGQSAGQDTAPLSSSDPQPIFLYPPVQRSVQKRAVKKMSVLGRQTCLECSFEIPDFPNHFPTYVHCSLCRYSTCCSRAYANHMINNHVPRKSPKYLALFKNYTACGVKLCCSSCLFASSEGDMMAKHLVFNPSHEFSNIIFRGPTWISHSRHIQPQDRSMKNTCPAYSPSKAATVKTKSVLPVKDDLEPEAALAAHTRPLLCQEEECLNIDAQEDEQPMKETEPASKKEQLSVKKLRVVLFALCCSTEQAAEHFRNPQRRIKRWLRRFQAFQEENLASLSEGKYLSLEAEEKLAEWVLTQREQQLPVNEETLFQKATKLGRSLEGGFKISYEWAVRFMLRHNLSMHTRRAVAHPLPKEVEDNAGCFIEFVQRQIHTQDLPLSMIAAIDEISLFLDVEVLSSDDKKENALQTVGTGEPWCDVVLTILADGSVLPTLVFYRGHVQQPANVPESIILEAKENGYSDDEVMELWASRVWQKHTECQNSKGMLVLDCHRTHLSEEVLSLLSASSTLPAVVPAGCSSKIQPLDVCIKRTVKNFLHKKWKEQAKEMADSTCDSDILLQLVLCWLAEVLEVISDSPELVQQSFLVASVLPGPDGTANSATRNADMQEELITALEEQLKLGEEQQPQEVAEGEDQPQNEECADPEILQQLFEGESETESFYGFEDADLDLMEI", "length": 1324, "header": "tr|A0A8V1AGU2-1|A0A8V1AGU2_CHICK Isoform 1 of Pogo transposable element with ZNF domain OS=Gallus gallus OX=9031 GN=POGZ PE=1 SV=1 CANONICAL=A0A8V1AGU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2/entry#A0A8V1AEB0-1", "sequence": { "sequence": "MADTDLFMECEEEELEPWQKISDVIEDSVVEDYNSVDKTTTAGNPLVQQGGQPLILTQNPTSGLGTMVTQPVLRPVQIMQNANHVTNSPVTSQPIFITTQGFPVRNVRPVQNTMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPAVGVPQVFSQVAQVRPGTTMPVRPTTNTFTTVIPATLTIRSTVPQSQSQQQMSIASFVTVKRPGVTGENSNEVAKLVNTLNTVPSLGQSPGPMVVSNSSPVHGSQRSSTSESSSSSLKVSSSPIPTFDLQDGGRKVCPRCDAQFRVTEALRGHMCYCCPEMVEFLKKRKSLDSEPNIQSAKPPSPEKTTAVASPPSSTPIPALSPPAKAPEPNEGMVDSSQSKLIMLVDDFYYGRDGGKVSQLLNFPKVPTSFRCPHCTKRLKNNIRFMNHMKHHVELDQQNGEVDVHTICQHCYRQFSTPFQLQCHLENVHSPYESTTKCKICEWAFESEPMFLQHMKDTHKPGEMPYVCQVCQYRSSLYSEVDSHFRMIHEDTRHLLCPYCLKVFKNGNAFQQHFMRHQKKSVYHCNKCRLQFLFAKDKIEHKLQHHKTFRKPKQLEGLKPGTKVTIRASRGQPRTVPISSNDMGQSAGQDTAPLSSSDPQPIFLYPPVQRSVQKRAVKKMSVLGRQTCLECSFEIPDFPNHFPTYVHCSLCRYSTCCSRAYANHMINNHVPRKSPKYLALFKNYTACGVKLCCSSCLFASSEGDMMAKHLVFNPSHEFSNIIFRGPTWISHSRHIQPQDRSMKNTCPAYSPSKAATVKTKSVLPVKDDLEPEAALAAHTRPLLCQEEECLNIDAQEDEQPMKETEPASKKEQLSVKKLRVVLFALCCSTEQAAEHFRNPQRRIKRWLRRFQAFQEENLASLSEGKYLSLEAEEKLAEWVLTQREQQLPVNEETLFQKATKLGRSLEGGFKISYEWAVRFMLRHNLSMHTRRAVAHPLPKEVEDNAGCFIEFVQRQIHTQDLPLSMIAAIDEISLFLDVEVLSSDDKKENALQTVGTGEPWCDVVLTILADGSVLPTLVFYRGHVQQPANVPESIILEAKENGYSDDEVMELWASRVWQKHTECQNSKGMLVLDCHRTHLSEEVLSLLSASSTLPAVVPAGCSSKIQPLDVCIKRTVKNFLHKKWKEQAKEMADSTCDSDILLQLVLCWLAEVLEVISDSPELVQQSFLVASVLPGPDGTANSATRNADMQEELITALEEQLKLGEEQQPQEVAEGEDQPQNEECADPEILQQLFEGESETESFYGFEDADLDLMEI", "length": 1284, "header": "tr|A0A8V1AEB0-1|A0A8V1AEB0_CHICK Computationally mapped isoform of Pogo transposable element with ZNF domain OS=Gallus gallus OX=9031 GN=POGZ PE=1 SV=1 CANONICAL=A0A8V1AGU2-1" }, "locus": { "chromosome": "25", "start_pos": 2763192, "end_pos": 2746497, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067833.1", "url": "https://www.ensembl.org/id/ENSGALT00010067833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041576.1", "url": "https://www.ensembl.org/id/ENSGALP00010041576.1" } ] } }, { "isoform_ac": "A0A8V1AGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2/entry#A0A8V1AGU2-1", "sequence": { "sequence": "MCAAFWDREGLILLDFLGPGQTASSDRVVALTELKAPTSRMADTDLFMECEEEELEPWQKISDVIEDSVVEDYNSVDKTTTAGNPLVQQGGQPLILTQNPTSGLGTMVTQPVLRPVQIMQNANHVTNSPVTSQPIFITTQGFPVRNVRPVQNTMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPAVGVPQVFSQVAQVRPGTTMPVRPTTNTFTTVIPATLTIRSTVPQSQSQQQMSIASFVTVKRPGVTGENSNEVAKLVNTLNTVPSLGQSPGPMVVSNSSPVHGSQRSSTSESSSSSLKVSSSPIPTFDLQDGGRKVCPRCDAQFRVTEALRGHMCYCCPEMVEFLKKRKSLDSEPNIQSAKPPSPEKTTAVASPPSSTPIPALSPPAKAPEPNEGMVDSSQSKLIMLVDDFYYGRDGGKVSQLLNFPKVPTSFRCPHCTKRLKNNIRFMNHMKHHVELDQQNGEVDVHTICQHCYRQFSTPFQLQCHLENVHSPYESTTKCKICEWAFESEPMFLQHMKDTHKPGEMPYVCQVCQYRSSLYSEVDSHFRMIHEDTRHLLCPYCLKVFKNGNAFQQHFMRHQKKSVYHCNKCRLQFLFAKDKIEHKLQHHKTFRKPKQLEGLKPGTKVTIRASRGQPRTVPISSNDMGQSAGQDTAPLSSSDPQPIFLYPPVQRSVQKRAVKKMSVLGRQTCLECSFEIPDFPNHFPTYVHCSLCRYSTCCSRAYANHMINNHVPRKSPKYLALFKNYTACGVKLCCSSCLFASSEGDMMAKHLVFNPSHEFSNIIFRGPTWISHSRHIQPQDRSMKNTCPAYSPSKAATVKTKSVLPVKDDLEPEAALAAHTRPLLCQEEECLNIDAQEDEQPMKETEPASKKEQLSVKKLRVVLFALCCSTEQAAEHFRNPQRRIKRWLRRFQAFQEENLASLSEGKYLSLEAEEKLAEWVLTQREQQLPVNEETLFQKATKLGRSLEGGFKISYEWAVRFMLRHNLSMHTRRAVAHPLPKEVEDNAGCFIEFVQRQIHTQDLPLSMIAAIDEISLFLDVEVLSSDDKKENALQTVGTGEPWCDVVLTILADGSVLPTLVFYRGHVQQPANVPESIILEAKENGYSDDEVMELWASRVWQKHTECQNSKGMLVLDCHRTHLSEEVLSLLSASSTLPAVVPAGCSSKIQPLDVCIKRTVKNFLHKKWKEQAKEMADSTCDSDILLQLVLCWLAEVLEVISDSPELVQQSFLVASVLPGPDGTANSATRNADMQEELITALEEQLKLGEEQQPQEVAEGEDQPQNEECADPEILQQLFEGESETESFYGFEDADLDLMEI", "length": 1324, "header": "tr|A0A8V1AGU2-1|A0A8V1AGU2_CHICK Isoform 1 of Pogo transposable element with ZNF domain OS=Gallus gallus OX=9031 GN=POGZ PE=1 SV=1 CANONICAL=A0A8V1AGU2-1" }, "locus": { "chromosome": "25", "start_pos": 2763192, "end_pos": 2745253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067832.1", "url": "https://www.ensembl.org/id/ENSGALT00010067832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041575.1", "url": "https://www.ensembl.org/id/ENSGALP00010041575.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "kinetochore assembly", "id": "GO:0051382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 992, "end_pos": 994, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 438, "end_pos": 465, "start_aa": "Phe", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU2" }, { "id": "PS51253", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51253" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH CENPB-type", "eco_id": "ECO_0000259", "start_pos": 927, "end_pos": 997, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 992, "end_pos": 994 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGU4-1", "uniprot_ac": "A0A8V1AGU4", "uniprot_id": "A0A8V1AGU4_CHICK", "mass": { "chemical_mass": 55701.0, "monoisotopic_mass": 55701.0 }, "refseq": { "ac": "NP_001012815", "name": "26S proteasome non-ATPase regulatory subunit 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012815" }, "gene_names": [ { "name": "PSMD5", "type": "recommended", "evidence": [ { "id": "A0A8V1AGU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4" } ] }, { "name": "PSMD5", "type": "synonym", "evidence": [ { "id": "NP_001012815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012815" } ] } ], "protein_names": [ { "name": "26S proteasome non-ATPase regulatory subunit 5", "type": "recommended", "evidence": [ { "id": "A0A8V1AGU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4/entry#names_and_taxonomy" } ] }, { "name": "26S proteasome non-ATPase regulatory subunit 5", "type": "synonym", "evidence": [ { "id": "NP_001012815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012815" } ] }, { "name": "proteasome (prosome, macropain) 26S subunit, non-ATPase, 5", "type": "synonym", "evidence": [ { "id": "NP_001012815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012815" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851610.1, SRR13267654.257755.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000308.1. On Sep 23, 2021 this sequence version replaced NP_001012815.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012815" } ] }, { "annotation": "Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4#function" }, { "database": "UniProtKB", "id": "ARBA00055861", "url": "https://www.uniprot.org/uniprotkb/ARBA00055861#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSMD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4", "locus": { "chromosome": "17", "start_pos": 8880445, "end_pos": 8887178, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027522", "url": "https://www.ensembl.org/id/ENSGALG00010027522" } ] } } ], "crossref": [ { "id": "A0A8V1AGU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "417125", "url": "https://www.ncbi.nlm.nih.gov/gene/417125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417125", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417125", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WGQEYIS", "url": "https://omabrowser.org/oma/group/WGQEYIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGU4", "url": "https://www.orthodb.org/?gene=A0A8V1AGU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13554", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13554", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13554:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13554:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9907900", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAVVELLERAARREAPLEELRALRLAVQAVPPAALRARLSDEHLAALFTLLSSSEREQLSACVAVLERLLQALDPLYVIQNLREELRKGLFHPDDSVKILSISQVGRIVENSDAVREILNSPELLRQIINCIGGEKIAVAKEAIKSLSRIAQTQDGLEALFVSSLLSDLKNVMGTNDVVRYRVYELIVEISSVSADSLNYCANSGLISDLIGELTGDDVLVRATCIEMVTSLAHSPHGRQYLAQQGIIDKISNIIIGAESDPFSGFYLPGFIKFFGNLAVVDSPQQICERYPVFMEKVFEMAESHDPTMNGVAVDTLGILGSSVEGKQVLQKARGRFQNLLNKIGHQAKNAPTELRLRCLDAVSSLLYLPPEQQTEDLLRMTESWFSSLSSQPLELFRSISTQPFPDLHCGALRVFTAIANQAWAQKLMLNSPGFVEYIVDRSVEPDKASKDAKYELVKALVNSKTIAEIFGNQYYLRLRAYLNEGPYYVKAVSTTAVEGAE", "length": 504, "header": "tr|A0A8V1AGU4-1|A0A8V1AGU4_CHICK Isoform 1 of 26S proteasome non-ATPase regulatory subunit 5 OS=Gallus gallus OX=9031 GN=PSMD5 PE=1 SV=1 CANONICAL=A0A8V1AGU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4/entry#A0A8V1AGU4-1", "sequence": { "sequence": "MAEAVVELLERAARREAPLEELRALRLAVQAVPPAALRARLSDEHLAALFTLLSSSEREQLSACVAVLERLLQALDPLYVIQNLREELRKGLFHPDDSVKILSISQVGRIVENSDAVREILNSPELLRQIINCIGGEKIAVAKEAIKSLSRIAQTQDGLEALFVSSLLSDLKNVMGTNDVVRYRVYELIVEISSVSADSLNYCANSGLISDLIGELTGDDVLVRATCIEMVTSLAHSPHGRQYLAQQGIIDKISNIIIGAESDPFSGFYLPGFIKFFGNLAVVDSPQQICERYPVFMEKVFEMAESHDPTMNGVAVDTLGILGSSVEGKQVLQKARGRFQNLLNKIGHQAKNAPTELRLRCLDAVSSLLYLPPEQQTEDLLRMTESWFSSLSSQPLELFRSISTQPFPDLHCGALRVFTAIANQAWAQKLMLNSPGFVEYIVDRSVEPDKASKDAKYELVKALVNSKTIAEIFGNQYYLRLRAYLNEGPYYVKAVSTTAVEGAE", "length": 504, "header": "tr|A0A8V1AGU4-1|A0A8V1AGU4_CHICK Isoform 1 of 26S proteasome non-ATPase regulatory subunit 5 OS=Gallus gallus OX=9031 GN=PSMD5 PE=1 SV=1 CANONICAL=A0A8V1AGU4-1" }, "locus": { "chromosome": "17", "start_pos": 8887139, "end_pos": 8881998, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066661.1", "url": "https://www.ensembl.org/id/ENSGALT00010066661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040812.1", "url": "https://www.ensembl.org/id/ENSGALP00010040812.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417125", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417125", "resource": "KEGG Pathway" }, { "id": "R-GGA-9907900", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9907900", "resource": "Reactome", "description": "Proteasome assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UT36-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "PSMD5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAQVLALLREVSRLEAPLEELRALQSVLQSVPLSELREHAAELHLGPLFSLLNENHREQTTLCVSILERLLQALEPVHVARNLKVDLQRGLTHTNDSVKILTLSQVGRIVDNSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDIVRYRVYELIVEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAIMDSPQQICERYPVFVEKVFEMTESQDPTMIGVAVDTIGILGSNVEGKQVLQKTGTRFERLLMKIGYQAKNASTELKIRCLDAVSSLFYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISNQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEYVMDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYVKPISTTAVEGAE", "length": 504 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LA61-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "Psmd5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAQAVTLLREVARLEAPLEELRALQSVVHAVPLHELREQAAELRLGPLFSLLNENNREQTALCVSILERLLQAVGPVHVARNLRVDLQRGLTHPDDSVKTLTLSQIGRIVENSEAVTEILNNTELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKNVMKTNDIVRYRVYELIIEISSVSLESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSGFYLPGFVKFFGNLAVMDSPQQICERYPVFLEKVFEMADSQDPTMIGVAVDTVGILGSSVEGKQVLQKTGTRFEHLLTRIGYQAKNASTELKTRCLDAVSSLLYLSPEQQTDDFLRMAESWFASLSQDSLELFRGISNQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEFVMDRSVEHDKASKDAKYELVKALANSKTVAEIFGNSNYLRLRTYLSEGPYYVKPVATTAVEGAD", "length": 504 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1N6Z0-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "PSMD5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLVRPGRFGLSQNSREGRLRPADLARLEEAPREPGAGRADWRTRAGGGIMAAQALALLREVSRLEAPLEELRALQSLLQSVPLSELREQAAELRLGPLFSLLNENHREQTTLCVSILERLLQALEPVHVARNLRVDLQRGLTHPNDSVKILTLSQVGRIVENSDAVTEILNNAELLKQIVYCIGGENLSVAKTAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDIVRYRVYELIVEISSVSPESLNCCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLACTHHGRQYLAQEGVIDQISNIIVGADADPFSSFYLPGFVKFFGNLAIMDSPQQICERYPIFMEKVFEMTESQDPTMIGVAVDTIGILGSNVEGKQVLQKTGTRFERLLMKIGYQAKNASTELKIRCLDALSSLFYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISNQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEYVMDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYVKPISTTAVEGAE", "length": 554 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QU35-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "psmd5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAAPIESLLNEICESEDPIEELKSLRTAVLATPVSGLRPAVSGARLEIIFSLLNTNDKEQIEVCVEILSRVLQALEPVQLAQNYRKALQSGLNHPDDSVKVLTLTQIGRVAGHAEGVTQMLNNVEILHDVIQCISVERIAVAKEAIAALSKLSNTKAGLDALFRSDLLNKLKDVMLTSDIIRYRVYELIVEVSTVSPVSLGYCANSGLISQMLEELTGDDVLVRATAIEMVTNLAQSQHGRQYLAQQGIMDKISNMIIAAESDTFSSLYLPGLVKFFGSLAIMDSPQQVCEKYPVFLEVVFSMVMNLDPTLTPVALDTLGVLGGTVEGKQVLQKTGEKFVSVLKRMSKVASDGATELRVRCLEALAQLLTLPVEQQTDDLLLTCESWFNCLSSQPMAMIRNISTQPFPELHCSALRIFTAIGCQPWAQQLMMDTPGFVEWVMDRSVGSGKEAKDCKFELVSALLSSSSVQKIFGAHNYLKLKTYLNEGPYYVTAVSAVTTEGAD", "length": 505 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V8G2-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "Psmd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAQAVSLLREVARLEAPLEELRALQSVVQAVPLHELREQAAELRLRPLFSLLNQNNREQTALCVSILERLLQAVEPIHLARNLRLDLQRGLTHPDDSVKTLTLSQIGRIVEDSEAVTEVLSNAELLRQVVCCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKNVMKTNDVVRYRVYELIIDISSVSSESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSGFYLPGFVKFFGNLAVMDSPQQICERYPVFLEKVFAMADSQDPTMIGVAVDTVGILGSSVEGKQVLQKTGTRFERLLTRIGYQAKNASTELKIRCLDAVSSLLYLSPEQQTDDFLGMTESWFSSVSRDSLELFRGISNQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEFVMDRSVEHDKTSKDAKYELVKALANSKTVAEIFGNSNYLRLRTYLSEGPYYVKPVATTAVEGAD", "length": 504 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q16401-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "PSMD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREKTTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDIVRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKVFEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIRCLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYVKPVSTTAVEGAE", "length": 504 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BJY1-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "Psmd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQAVSLLREVARLEAPLEELRALQSVVQAVPLHELREQAAELRLRPLFSLLNQNNREQTALCVSILERLLQAVEPIHLARNLRLDLQRGLTHPDDSVKTLTLSQIGRIVENSEAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKNVMKTNDVVRYRVYELIIDISSVSSESLNYCTTSGLVTQLLKELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSGFYLPGFVKFFGNLAVMDSPQQICERYPVFLEKVFEMADSQDPTMIGVAVDTVGILGSSVEGKQVLQKTGTRFERVLMRVGYQAKNASTELKIRCLDAVSSLLYLSPEQQTDDFLGMTESWFSSMSRDSLELFRGISNQPFPELHCAALKVFTAIADQPWAQRLMFNSPGFVEFVMDRSVEHDKASKDAKYELVKALANSKTVAEIFGNSNYLRLRAYLSEGPYYVKPVATTAVEGAD", "length": 504 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VYG1-1", "protein_name": "26S proteasome non-ATPase regulatory subunit 5", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEMEDNWWVTKLKALESKPQRLDALTAMNSAIAKEAALPRQIIERLLTTDQLYDCANPAADSHVPKDQAVDVTLELLCHCLDQLAMDTADEQLSSLLRRGLTHSNPALRAQVLASLFKKLLRQLTVGQVLTLPNNELIFLILDELKQPDTQSTSLAINILSIVLPQRISNADVQAKLVQLLKQNEIVRCRAYELAVVLAKKSATLLSDVTFILDAALSELDNDDVLLQASVMELLVPLAEQNHGLSYMERRRVLDIISYRVQRVEEHPLDALLVPSIMKFFGKISVYQPLKIIGGYPHMLACLFMQLQSEDESILPTAMDTLANLATTPQGKILLNMHFSGAMEKSFKKYGSHTKKLSAHIKKRLLNSLDVIYDFKTPPATEIINIGKNWYECFAGGAHANIIMDLINTPFPDLQMAALSFLKTICKYNWGIVALKNTGGAVEFLLSRQKDLHRDIKYMKWQIMEILSASAEFSPTETIRFTAYVNEGPYHVQADLDVATEPQGNA", "length": 506 }, "evidence": [ { "id": "A0A8V1AGU4", "url": "https://omabrowser.org/oma/group/A0A8V1AGU4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "proteasome regulatory particle, base subcomplex", "id": "GO:0008540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome regulatory particle assembly", "id": "GO:0070682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGU5-1", "uniprot_ac": "A0A8V1AGU5", "uniprot_id": "A0A8V1AGU5_CHICK", "mass": { "chemical_mass": 50234.0, "monoisotopic_mass": 50234.0 }, "refseq": {}, "gene_names": [ { "name": "ENPP7", "type": "recommended", "evidence": [ { "id": "A0A8V1AGU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU5" } ] } ], "protein_names": [ { "name": "Ectonucleotide pyrophosphatase/phosphodiesterase 7", "type": "synonym", "evidence": [ { "id": "A0A8V1AGU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENPP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU5", "locus": { "chromosome": "18", "start_pos": 10273380, "end_pos": 10277048, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029236", "url": "https://www.ensembl.org/id/ENSGALG00010029236" } ] } } ], "crossref": [ { "id": "A0A8V1AGU5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16018", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16018", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGU5", "url": "https://www.orthodb.org/?gene=A0A8V1AGU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMP8", "url": "https://www.orthodb.org/?gene=A0A8V1AMP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10151:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10151:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AGU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSALPLLKGEMMFPSLALLFAALPVAKGSPVPHTSGRDKVLLVSFDGFRWDYDQDVDTPNLDAMAAEGVKAQYMTPAFITLTSPCHFTLLTGKYMENHGVIHNMCFNTSTGVKLPYYSTQGIDSWWDNGSLPIWITAQRQGLKTGSIHFPGTKAKYQGEEVSMKLVEPPLFNYSNETIWRQNIDTAMEWFTVNNLDFITLYFGEPDSTGHKYGPESTQRRNMVGQVDKTIGYLRQRIRESGLESNLNLIITSDHGMETVIKSNEIYLRNVENFTFSDIQFELLDYGPNGLLIPKEGKLEHVYSVLKNAHPKLHVYKKEEFPKRFHYANHPRITPLLMYGDPGYVIHGRYKVQFNAGEHGFDNEAMNMKTIFRAVGPAFKQGLLVEPFESVNVYALLCELLGIAPEPHDGSLEVTRPMLRSSAPLLAAIKLPVTLGIALILSCGRGVY", "length": 447, "header": "tr|A0A8V1AGU5-1|A0A8V1AGU5_CHICK Isoform 1 of Ectonucleotide pyrophosphatase/phosphodiesterase 7 OS=Gallus gallus OX=9031 GN=ENPP7 PE=4 SV=1 CANONICAL=A0A8V1AGU5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU5/entry#A0A8V1AGU5-1", "sequence": { "sequence": "MSALPLLKGEMMFPSLALLFAALPVAKGSPVPHTSGRDKVLLVSFDGFRWDYDQDVDTPNLDAMAAEGVKAQYMTPAFITLTSPCHFTLLTGKYMENHGVIHNMCFNTSTGVKLPYYSTQGIDSWWDNGSLPIWITAQRQGLKTGSIHFPGTKAKYQGEEVSMKLVEPPLFNYSNETIWRQNIDTAMEWFTVNNLDFITLYFGEPDSTGHKYGPESTQRRNMVGQVDKTIGYLRQRIRESGLESNLNLIITSDHGMETVIKSNEIYLRNVENFTFSDIQFELLDYGPNGLLIPKEGKLEHVYSVLKNAHPKLHVYKKEEFPKRFHYANHPRITPLLMYGDPGYVIHGRYKVQFNAGEHGFDNEAMNMKTIFRAVGPAFKQGLLVEPFESVNVYALLCELLGIAPEPHDGSLEVTRPMLRSSAPLLAAIKLPVTLGIALILSCGRGVY", "length": 447, "header": "tr|A0A8V1AGU5-1|A0A8V1AGU5_CHICK Isoform 1 of Ectonucleotide pyrophosphatase/phosphodiesterase 7 OS=Gallus gallus OX=9031 GN=ENPP7 PE=4 SV=1 CANONICAL=A0A8V1AGU5-1" }, "locus": { "chromosome": "18", "start_pos": 10277030, "end_pos": 10273395, "strand": 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OS=Gallus gallus OX=9031 GN=ENPP7 PE=4 SV=1 CANONICAL=A0A8V1AGU5-1" }, "locus": { "chromosome": "18", "start_pos": 10277030, "end_pos": 10274018, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070663.1", "url": "https://www.ensembl.org/id/ENSGALT00010070663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043354.1", "url": "https://www.ensembl.org/id/ENSGALP00010043354.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 75, "start_aa": "Thr", "end_pos": 75, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr75", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKI0-1", "uniprot_ac": "A0A8V1AKI0", "uniprot_id": "A0A8V1AKI0_CHICK", "mass": { "chemical_mass": 39208.0, "monoisotopic_mass": 39208.0 }, "refseq": { "ac": "XP_040508245", "name": "induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508245" }, "gene_names": [ { "name": "MCL1", "type": "recommended", "evidence": [ { "id": "A0A8V1AKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ] }, { "name": "MCL1", "type": "synonym", "evidence": [ { "id": "XP_040508245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508245" } ] } ], "protein_names": [ { "name": "BCL2 family apoptosis regulator", "type": "synonym", "evidence": [ { "id": "A0A8V1AKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0/entry#names_and_taxonomy" } ] }, { "name": "induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040508245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508245" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508245" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0", "locus": { "chromosome": "25", "start_pos": 2261271, "end_pos": 2255543, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028459", "url": "https://www.ensembl.org/id/ENSGALG00010028459" } ] } } ], "crossref": [ { "id": "A0A8V1AKI0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKI0", "database": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395674", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395674", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FFAPTRC", "url": "https://omabrowser.org/oma/group/FFAPTRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8S6", "url": "https://www.orthodb.org/?gene=A0A8V1A8S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIP4", "url": "https://www.orthodb.org/?gene=A0A8V1AIP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKI0", "url": "https://www.orthodb.org/?gene=A0A8V1AKI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11256:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11256:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040508245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508245", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFAVKRNAVIGFNLYCGGGSPGLVPASPAGEQTPPPAAAAPAAAAATVAEVPRPLIGSAGLWAAAGRAEAPRAPIGSGAAPHAPIGSAAARRAPPDSTSRPVALWSPEEELDGCEPESERGPGGDSLPGTPPELPDLIPDELRQESLELILRYLREAAGEAEPGVKKLFPGLLGGPGRPCRASSAVMEKALETLRRVGDGVMQKHELAFQGMLRKLEIKKEDDLQAVCEVAAHVFNDGVTNWGRVVTLISFGAFVAKHLKSINQEKCITSLAGIITDALVSSKREWLMSQGGWEGFVDFFRVEDLESSIRNVLMAFAGVAGLGASLAYMIRPGPHPRPPGMGHPQNEAAVTAPRGLQVRNFFLTGDLNKWLF", "length": 372, "header": "tr|A0A8V1AKI0-1|A0A8V1AKI0_CHICK Isoform 1 of BCL2 family apoptosis regulator OS=Gallus gallus OX=9031 GN=MCL1 PE=3 SV=1 CANONICAL=A0A8V1AKI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0/entry#A0A8V1A8S6-1", "sequence": { "sequence": "MFAVKRNAVIGFNLYCGGGSPGLVPASPAGEQTPPPAAAAPAAAAATVAEVPRPLIGSAGLWAAAGRAEAPRAPIGSGAAPHAPIGSAAARRAPPDSTSRPVALWSPEEELDGCEPESERGPGGDSLPGTPPELPDLIPDELRQESLELILRYLREAAGEAEPGVKKLFPGLLGGPGRPCRASSAVMEKALETLRRVGDGVMQKHELAFQGMLRKLEIKKEDDLQAVCEVAAHVFNDGVTNWGRVVTLISFGAFVAKHLKSINQEKCITSLAGIITDALVSSKREWLMSQGGWEGFVDFFRVEDLESSIRNVLMAFAGVAGLGASLAYMIRKWRS", "length": 335, "header": "tr|A0A8V1A8S6-1|A0A8V1AKI0_CHICK Computationally mapped isoform of BCL2 family apoptosis regulator OS=Gallus gallus OX=9031 GN=MCL1 PE=3 SV=1 CANONICAL=A0A8V1AKI0-1" }, "locus": { "chromosome": "25", "start_pos": 2259178, "end_pos": 2255573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068921.1", "url": "https://www.ensembl.org/id/ENSGALT00010068921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042363.1", "url": "https://www.ensembl.org/id/ENSGALP00010042363.1" } ] } }, { "isoform_ac": "A0A8V1AIP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0/entry#A0A8V1AIP4-1", "sequence": { "sequence": "MFAVKRNAVIGFNLYCGGGSPGLVPASPAGEQTPPPAAAAPAAAAATVAEVPRPLIGSAGLWAAAGRAEAPRAPIGSGAAPHAPIGSAAARRAPPDSTSRPVALWSPEEELDGCEPESERGPGGDSLPGTPPELPDLIPDELRQESLELILRYLREAAGEAEPGVKKLFPGLLGGPGRPCRASSAVMEKALETLRRVGDGVMQKHELAFQGMLRKLEIKKEDDLQAVCEVAAHVFNDGVTNWGRVVTLISFGAFVAKHLKSINQEKCITSLAGIITDALVSSKREWLMSQGGWEGFVDFFRVEDLESSIRNVLMAFAGVAGLGASLAYMIR", "length": 331, "header": "tr|A0A8V1AIP4-1|A0A8V1AKI0_CHICK Computationally mapped isoform of BCL2 family apoptosis regulator OS=Gallus gallus OX=9031 GN=MCL1 PE=3 SV=1 CANONICAL=A0A8V1AKI0-1" }, "locus": { "chromosome": "25", "start_pos": 2258950, "end_pos": 2255573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068919.1", "url": "https://www.ensembl.org/id/ENSGALT00010068919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042361.1", "url": "https://www.ensembl.org/id/ENSGALP00010042361.1" } ] } }, { "isoform_ac": "A0A8V1AKI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0/entry#A0A8V1AKI0-1", "sequence": { "sequence": "MFAVKRNAVIGFNLYCGGGSPGLVPASPAGEQTPPPAAAAPAAAAATVAEVPRPLIGSAGLWAAAGRAEAPRAPIGSGAAPHAPIGSAAARRAPPDSTSRPVALWSPEEELDGCEPESERGPGGDSLPGTPPELPDLIPDELRQESLELILRYLREAAGEAEPGVKKLFPGLLGGPGRPCRASSAVMEKALETLRRVGDGVMQKHELAFQGMLRKLEIKKEDDLQAVCEVAAHVFNDGVTNWGRVVTLISFGAFVAKHLKSINQEKCITSLAGIITDALVSSKREWLMSQGGWEGFVDFFRVEDLESSIRNVLMAFAGVAGLGASLAYMIRPGPHPRPPGMGHPQNEAAVTAPRGLQVRNFFLTGDLNKWLF", "length": 372, "header": "tr|A0A8V1AKI0-1|A0A8V1AKI0_CHICK Isoform 1 of BCL2 family apoptosis regulator OS=Gallus gallus OX=9031 GN=MCL1 PE=3 SV=1 CANONICAL=A0A8V1AKI0-1" }, "locus": { "chromosome": "25", "start_pos": 2261265, "end_pos": 2255573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068922.1", "url": "https://www.ensembl.org/id/ENSGALT00010068922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042364.1", "url": "https://www.ensembl.org/id/ENSGALP00010042364.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395674", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P97287-1", "protein_name": "Induced myeloid leukemia cell differentiation protein Mcl-1 homolog", "gene_name": "Mcl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFGLRRNAVIGLNLYCGGASLGAGGGSPAGARLVAEEAKARREGGGEAALLPGARVVARPPPVGAEDPDVTASAERRLHKSPGLLAVPPEEMAASAAAAIVSPEEELDGCEPEAIGKRPAVLPLLERVSEAAKSSGADGSLPSTPPPPEEEEDDLYRQSLEIISRYLREQATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGGIRNVLLAFAGVAGVGAGLAYLIR", "length": 331 }, "evidence": [ { "id": "A0A8V1AKI0", "url": "https://omabrowser.org/oma/group/A0A8V1AKI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q07820-1", "protein_name": "Induced myeloid leukemia cell differentiation protein Mcl-1", "gene_name": "MCL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR", "length": 350 }, "evidence": [ { "id": "A0A8V1AKI0", "url": "https://omabrowser.org/oma/group/A0A8V1AKI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1P3-1", "protein_name": "Induced myeloid leukemia cell differentiation protein Mcl-1 homolog", "gene_name": "Mcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGLRRNAVIGLNLYCGGASLGAGGGSPAGTRLAAEEAKARREGGGEAALLPGARVVARPPPVGAEDPDVTASAERRLLKSPGLLAVPPEEMAASAAAIMSPEEELDGCEPEVLSKRPAVLPLLERVSEAAKSSGADGSLPSTPPPPEEEDDELYRQSLEIISRYLREQATGSKDAKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSFSRVMTHVFKDGVTNWGRIVTLISFGAFVAKHLKSINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVQDLEGGIRNVLLAFAGVAGVGAGLAYLIR", "length": 330 }, "evidence": [ { "id": "A0A8V1AKI0", "url": "https://omabrowser.org/oma/group/A0A8V1AKI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "Bcl-2 family protein complex", "id": "GO:0097136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "release of cytochrome c from mitochondria", "id": "GO:0001836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001836", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "id": "GO:2001240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "extrinsic apoptotic signaling pathway in absence of ligand", "id": "GO:0097192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "id": "GO:1903378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903378", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "negative regulation of anoikis", "id": "GO:2000811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "BH domain binding", "id": "GO:0051400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "channel activity", "id": "GO:0015267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" }, { "name": "BH3 domain binding", "id": "GO:0051434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051434", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI0" }, { "id": "SM00337", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00337" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bcl-2 Bcl-2 homology region 1-3", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 293, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJN3-1", "uniprot_ac": "A0A8V1AJN3", "uniprot_id": "A0A8V1AJN3_CHICK", "mass": { "chemical_mass": 37063.0, "monoisotopic_mass": 37063.0 }, "refseq": { "ac": "XP_040505414", "name": "nuclear distribution protein nudE-like 1 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505414" }, "gene_names": [ { "name": "NDEL1", "type": "recommended", "evidence": [ { "id": "A0A8V1AJN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3" } ] }, { "name": "NDEL1", "type": "synonym", "evidence": [ { "id": "XP_040505414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505414" } ] } ], "protein_names": [ { "name": "NudE neurodevelopment protein 1 like 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AJN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3/entry#names_and_taxonomy" } ] }, { "name": "nuclear distribution protein nudE-like 1 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_040505414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505414" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3", "locus": { "chromosome": "18", "start_pos": 2344439, "end_pos": 2321108, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029340", "url": "https://www.ensembl.org/id/ENSGALG00010029340" } ] } } ], "crossref": [ { "id": "A0A8V1AJN3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001163", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001163", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417317", "url": "https://www.ncbi.nlm.nih.gov/gene/417317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PRW9", "url": "https://www.orthodb.org/?gene=A0A1D5PRW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A452J851", "url": "https://www.orthodb.org/?gene=A0A452J851", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACD0", "url": "https://www.orthodb.org/?gene=A0A8V1ACD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJN3", "url": "https://www.orthodb.org/?gene=A0A8V1AJN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN99", "url": "https://www.orthodb.org/?gene=A0A8V1AN99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10921:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10921:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040505414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PRW9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452J851", "url": "https://www.uniprot.org/uniprotkb/A0A452J851", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A452J851-1", "url": "https://www.uniprot.org/uniprotkb/A0A452J851-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSEEIPTFSSPKEETAYWKELSLKYKQSFQEAREELAEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVETLKEKLEHQYAQSYKQVSLLEDDLSQTRAIKDQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDDKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGSENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNANSSMMSSNGTKYPHPGHTSFFDKGREKVIFPTLVMGQ", "length": 328, "header": "tr|A0A8V1AJN3-1|A0A8V1AJN3_CHICK Isoform 1 of NudE neurodevelopment protein 1 like 1 OS=Gallus gallus OX=9031 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A8V1AJN3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PRW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3/entry#A0A1D5PRW9-1", "sequence": { "sequence": "MDSEEIPTFSSPKEETAYWKELSLKYKQSFQEAREELAEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVETLKEKLEHQYAQSYKQVSLLEDDLSQTRAIKDQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDDKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGSENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNANSSMMSSNGTKYPHPGHTSFFDKGPCTLFPAPNCRWSLKQPRVLVDPVQSAAAAL", "length": 346, "header": "tr|A0A1D5PRW9-1|A0A1D5PRW9_CHICK Computationally mapped isoform of NudE neurodevelopment protein 1 like 1 OS=Gallus gallus OX=9031 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A8V1AJN3-1" }, "locus": { "chromosome": "18", "start_pos": 2339537, "end_pos": 2328867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070961.1", "url": "https://www.ensembl.org/id/ENSGALT00010070961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043652.1", "url": "https://www.ensembl.org/id/ENSGALP00010043652.1" } ] } }, { "isoform_ac": "A0A452J851-1", "url": 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} }, { "isoform_ac": "A0A8V1ACD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN3/entry#A0A8V1ACD0-1", "sequence": { "sequence": "MDSEEIPTFSSPKEETAYWKELSLKYKQSFQEAREELAEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVETLKEKLEHQYAQSYKQVSLLEDDLSQTRAIKDQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDDKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGSENSFPSPKVCLFAAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNANSSMMSSNGTKYPHPGHTSFFDKGAVNGFDQGTPGLGASRPSSAPGMLPLSV", "length": 348, "header": "tr|A0A8V1ACD0-1|A0A8V1AJN3_CHICK Computationally mapped isoform of NudE neurodevelopment protein 1 like 1 OS=Gallus gallus OX=9031 GN=NDEL1 PE=3 SV=1 CANONICAL=A0A8V1AJN3-1" }, "locus": { "chromosome": "18", "start_pos": 2342925, "end_pos": 2328867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070963.1", "url": "https://www.ensembl.org/id/ENSGALT00010070963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043654.1", "url": 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"tr|A0A8V1AJI3-1|A0A8V1AJI3_CHICK Isoform 1 of Mitochondrial-processing peptidase subunit alpha OS=Gallus gallus OX=9031 GN=PMPCA PE=1 SV=1 CANONICAL=A0A8V1AJI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI3/entry#A0A8V1A7K8-1", "sequence": { "sequence": "MAAAVAWLRRGAWGPARRCGLAAARSYSGGGSYPNVSLTCPLPGVPKAVFAAAEGRERFETRVTVLENGLRVASQNKFGQFCTVGLLINSGSRHEAKYLSGIAHFLEKLAFSSTAQFSSKDEILLTLEKHGGICDCQASRDTIMYAVSADAKGLDTVVNLLADVALQPRLSDEEIEMTRMAIRFELEDLNMRPDPEPLLTEMIHAAAYRENTVGLKRFCPVENTDKIDQKVLHSYLRNYYTPDRMVLAGVGIEHEQLVECAKKYLLGVEPVWGSAQTKEVDRSVAQYTGGIVKVEKDMSDVSLGPTPIPELTHIMIGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFTRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPKQVELERAKTQLKSMLMMNLESRPVIFEDVGRQVLATNTRKLPHELCALISKVKSTDIKRVVTKMLHKKPAVAALGDLTDLPTYEHIQEALSSKDGRLPRMYRLFR", "length": 498, "header": "tr|A0A8V1A7K8-1|A0A8V1A7K8_CHICK Computationally mapped isoform of Mitochondrial-processing peptidase subunit alpha OS=Gallus gallus OX=9031 GN=PMPCA PE=1 SV=1 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"MDQSLGWCGLAAARSYSGGGSYPNVSLTCPLPGVPKAVFAAAEGRERFETRVTVLENGLRVASQNKFGQFCTVGLLINSGSRHEAKYLSGIAHFLEKLAFSSTAQFSSKDEILLTLEKHGGICDCQASRDTIMYAVSADAKGLDTVVNLLADVALQPRLSDEEIEMTRMAIRFELEDLNMRPDPEPLLTEMIHAAAYRENTVGLKRFCPVENTDKIDQKVLHSYLRNYYTPDRMVLAGVGIEHEQLVECAKKYLLGVEPVWGSAQTKEVDRSVAQYTGGIVKVEKDMSDVSLGPTPIPELTHIMIGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFTRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPKQVREMVEIITREFILMAGAIGEVELERAKTQLKSMLMMNLESRPVIFEDVGRQVLATNTRKLPHELCALISKVKSTDIKRVVTKMLHKKPAVAALGDLTDLPTYEHIQEALSSKDGRLPRMYRLFR", "length": 508, "header": "tr|A0A8V1ACJ0-1|A0A8V1AJI3_CHICK Computationally mapped isoform of Mitochondrial-processing peptidase subunit alpha OS=Gallus gallus OX=9031 GN=PMPCA PE=1 SV=1 CANONICAL=A0A8V1AJI3-1" }, "locus": { "chromosome": "17", "start_pos": 8497687, "end_pos": 8492115, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068193.1", "url": "https://www.ensembl.org/id/ENSGALT00010068193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041936.1", "url": "https://www.ensembl.org/id/ENSGALP00010041936.1" } ] } }, { "isoform_ac": "A0A8V1AJI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI3/entry#A0A8V1AJI3-1", "sequence": { "sequence": "MAAAVAWLRRGAWGPARRCGLAAARSYSGGGSYPNVSLTCPLPGVPKAVFAAAEGRERFETRVTVLENGLRVASQNKFGQFCTVGLLINSGSRHEAKYLSGIAHFLEKLAFSFSSKDEILLTLEKHGGICDCQASRDTIMYAVSADAKGLDTVVNLLADVALQPRLSDEEIEMTRMAIRFELEDLNMRPDPEPLLTEMIHAAAYRENTVGLKRFCPVENTDKIDQKVLHSYLRNYYTPDRMVLAGVGIEHEQLVECAKKYLLGVEPVWGSAQTKEVDRSVAQYTGGIVKVEKDMSDVSLGPTPIPELTHIMIGLESCSFLEEDFIPFAVLNMMMGGGGSFSAGGPGKGMFTRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIHASADPKQVREMVEIITREFILMAGAIGEVELERAKTQLKSMLMMNLESRPVIFEDVGRQVLATNTRKLPHELCALISKVKSTDIKRVVTKMLHKKPAVAALGDLTDLPTYEHIQEALSSKDGRLPRMYRLFR", "length": 515, "header": "tr|A0A8V1AJI3-1|A0A8V1AJI3_CHICK Isoform 1 of Mitochondrial-processing peptidase subunit alpha OS=Gallus gallus OX=9031 GN=PMPCA PE=1 SV=1 CANONICAL=A0A8V1AJI3-1" }, "locus": { "chromosome": "17", "start_pos": 8496695, "end_pos": 8492115, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068192.1", "url": "https://www.ensembl.org/id/ENSGALT00010068192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041935.1", "url": "https://www.ensembl.org/id/ENSGALP00010041935.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 302, "start_aa": "Thr", "end_pos": 302, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr302", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8949664", "name": 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"mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI3" } ], "pmid": "" }, { "name": "mitochondrial processing peptidase complex", "id": "GO:0017087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJI3", "url": 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"monoisotopic_mass": 263172.0 }, "refseq": {}, "gene_names": [ { "name": "CACNA1G", "type": "recommended", "evidence": [ { "id": "A0A8V1AKA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ] } ], "protein_names": [ { "name": "Voltage-dependent T-type calcium channel subunit alpha-1G", "type": "recommended", "evidence": [ { "id": "A0A8V1AKA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8/entry#names_and_taxonomy" } ] }, { "name": "Voltage-gated calcium channel subunit alpha Cav3.1", "type": "synonym", "evidence": [ { "id": "A0A8V1AKA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the `low-voltage activated (LVA)` group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY2#function" }, { "database": "UniProtKB", "id": "RU003808", "url": "https://www.uniprot.org/uniprotkb/RU003808#function" }, { "database": "UniProtKB", "id": "A0A8V1ANI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CACNA1G", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8", "locus": { "chromosome": "18", "start_pos": 10825827, "end_pos": 10930642, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029724", "url": "https://www.ensembl.org/id/ENSGALG00010029724" } ] } } ], "crossref": [ { "id": "IPR002077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEX9", "url": "https://www.orthodb.org/?gene=A0A8V1AEX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKA8", "url": "https://www.orthodb.org/?gene=A0A8V1AKA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANI6", "url": "https://www.orthodb.org/?gene=A0A8V1ANI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APY2", "url": "https://www.orthodb.org/?gene=A0A8V1APY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45628:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45628:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AEX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEDGPRAADEEPEPGRAKTFIRLNDLSGAGGRPGPGEREVGSGDSEAEALPYPALAPVVFFYLSQESRPRSWCLRLVCNPWFERVSMLVILLNCVTLGMFHPCEDIACDSPRCRILQSFDDFIFAFFAVEMIVKMIALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLPENFSIPYTVDLERYYQTENEDENPFICSQPRENGMRYCRSIPTRREEGLECTLDYYSYNDTTNTSCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMKEQRVRYLSNASTLASFSEPGSCYDELLKYLVYIARKGSKQLVELYRVAGVRMGFLASPASKVERHAGKRRSRRRSSVHHLIHHHHHHHHHYHLGNGNLRAPRASPEISDVDTGSLHNGTNRLMLPPSAPNPHMAPTATASGTESVHSIYHADCHVEPLRCRVALPQPSPEDIPRSVVMGSKVYPTVHPSTSHEVRKEKSLGEEAMGAGSSTLSGLNIPPGPYSTMHKLLETQSTGFLSVHVTDKGDGFRGPCPSSCKIASPCTKLDGGSRSPESCPYCLKALANEAEQTDNETDSDSEGVYEFTQDAHYSDQRDPQRGRAWARSSSRVLAFWRVVCETFQKIVDSKYFGRGIMVAILINTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKVLVYGPFGYIKNPYNIFDGIIVVISVWEIVGQQGGGLSVLRTFRLMRVLKLVRFMPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQTEGDASKSDSEGELFLRSLEEEGGLKKNLSNPVLMALSEHPELKKSLTPPLIIHTAATPMPMPKSAMFGDAAQGYESRRASGVSMDPAAYELKSPPSTRSSPHSPWSAGSSWPSRRSSWNSIGRAPSLKRRGQSSERRSLLSGEGKESSEDGESSDEERSSRAGSVNGSLPHRMESLEAKGSFDLQDTLQVPSLYRTSSMHSSRTSTSEHQDCNGKTSPGLLVHQLHLDDPRPDCDDADDEGNMSKRDRMKAWVRAHLPTCCKERDSWSIYVFAPHSRFRLMCNKIITHKMFDHIVLVIIFLNCITIAMERPKIEPHSAERIFLTLSNYIFTVIFLTEMTVKVVALGLCFGEKAYLKSSWNVLDGVLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFICQGEDTRNITNKSDCAEASYKWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPVMNYNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEAKRREEKRLRRLEKKRRSKEKQMAEAQCKPYYSDYSRFRFLIHQMCTSHYLDLFITGVIGLNVITMAMEHYQQPKVLDEALKICNYIFTVIFVLESVSKLIAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDDTHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELEMEMKTISPGQHSPSDIFTWMGGVGGERPESPRGCPHPLQIQERHLFDTISLLIQESLEGELKLMDNLSGSVCHHYALPAPEYYSSENQAELRCRDAALALSPCQDLLSVRKPSVGRTHSLPNDSYMFHTSQPRSRPSTASLRDGNPAQHKVHSGSKASVQSQPADTSSLLQIPKDHFHHMRAHDPLVRESKAPAAAPVHSPSAERLLRRQMAIRNDSSDSKENLHAELSELPNPDIPSAPQEESAAALTPSEGEDLAAWSRASVHTQHHSHNQYNVSKQAPASCACADSYQETPGDSMDQEVSETNSSLEPFPSETCTASSACSEAQPLTPKRNIGSTGSVTLKDLKKYHSVDTQGLLKKPPSWLDDQRRHSIEICSMENSPQHHSTSSSSGFISQVVSEMEGLQGTRQKKKLSPPCISIDPPSEQGLLPRGPHSVSPARGDTCLRRRAPSCDSKDSVDIGDSLLPDSMSASPTPKKDLLTLPSFSFDQNEVEP", "length": 2347, "header": "tr|A0A8V1AKA8-1|A0A8V1AKA8_CHICK Isoform 1 of Voltage-dependent T-type calcium channel subunit alpha-1G OS=Gallus gallus OX=9031 GN=CACNA1G PE=3 SV=1 CANONICAL=A0A8V1AKA8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8/entry#A0A8V1AEX9-1", "sequence": { "sequence": "MLVILLNCVTLGMFHPCEDIACDSPRCRILQSFDDFIFAFFAVEMIVKMIALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLPENFSIPYTVDLERYYQTENEDENPFICSQPRENGMRYCRSIPTRREEGLECTLDYYSYNDTTNTSCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMKEQRVRYLSNASTLASFSEPGSCYDELLKYLVYIARKGSKQLVELYRVAGVRMGFLASPASKVERHAGKRRSRRRSSVHHLIHHHHHHHHHYHLGNGNLRAPRASPEISDVDTGSLHNGTNRLMLPPSAPNPHMAPTATASGTESVHSIYHADCHVEPLRCRVALPQPSPEDIPRSVVMGSKVYPTVHPSTSHEVRKEKSLGEEAMGAGSSTLSGLNIPPGPYSTMHKLLETQSTGFLSVHVTDKGDGFRGPCPSSCKIASPCTKLDGGSRSPESCPYCLKALANEAEQTDNETDSDSEGVYEFTQDAHYSDQRDPQRGRAWARSSSRVLAFWRVVCETFQKIVDSKYFGRGIMVAILINTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKVLVYGPFGYIKNPYNIFDGIIVVISVWEIVGQQGGGLSVLRTFRLMRVLKLVRFMPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQTEGDASKSDSEGELFLRSLEEEGGLKKNLSNPVLMALSEHPELKKSLTPPLIIHTAATPMPMPKSAMFGDAAQGYESRRASGVSMDPAAYELKSPPSTRSSPHSPWSAGSSWPSRRSSWNSIGRAPSLKRRGQSSERRSLLSGEGKESSEDGESSDEERSSRAGSVNGSLPHRMESLEAKGSFDLQDTLQVPSLYRTSSMHSSRTSTSEHQDCNGKTSPGLLVHQLHLDDPRPDCDDADDEGNMSKRDRMKAWVRAHLPTCCKERDSWSIYVFAPHSRFRLMCNKIITHKMFDHIVLVIIFLNCITIAMERPKIEPHSAERIFLTLSNYIFTVIFLTEMTVKVVALGLCFGEKAYLKSSWNVLDGVLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFICQGEDTRNITNKSDCAEASYKWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPVMNYNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEAKRREEKRLRRLEKKRRKAQCKPYYSDYSRFRFLIHQMCTSHYLDLFITGVIGLNVITMAMEHYQQPKVLDEALKICNYIFTVIFVLESVSKLIAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDDTHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELEMEMKTISPGQHSPSDIFTWMGGVGGERPESPRGCPHPLQIQAELRCRDAALALSPCQDLLSVRKPSVGRTHSLPNDSYMFHTSQPRSRPSTASLRDGNPAQHKVHSGSKASVQSQPADTSSLLQIPKDHFHHMRAHDPLVRESKAPAAAPVHSPSAERLLRRQMAIRNDSSDSKENLHAELSELPNPDIPSAPQEESAAALTPSEGEDLAAWSRASVHTQHHSHNQYNVSKQAPASCACADSYQETPGDSMDQEVSETNSSLEPFPSETCTASSACSEAQPLTPKRNIGSTGSVTLKDLKKYHSVDTQGLLKKPPSWLDDQRRHSIEICSMENSPQHHSTSSSSGFISQVVSEMEGLQGTRQKKKLSPPCISIDPPSEQGLLPRGPHSVSPARGDTCLRRRAPSCDSKDSVDIGDSLLPDSMSASPTPKKDLLTLPSFSFDQNEVEP", "length": 2206, "header": "tr|A0A8V1AEX9-1|A0A8V1AKA8_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha-1G OS=Gallus gallus OX=9031 GN=CACNA1G PE=3 SV=1 CANONICAL=A0A8V1AKA8-1" }, "locus": { "chromosome": "18", "start_pos": 10906739, "end_pos": 10825872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071899.1", "url": "https://www.ensembl.org/id/ENSGALT00010071899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044589.1", "url": "https://www.ensembl.org/id/ENSGALP00010044589.1" } ] } }, { "isoform_ac": "A0A8V1AKA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8/entry#A0A8V1AKA8-1", "sequence": { "sequence": "MDEDGPRAADEEPEPGRAKTFIRLNDLSGAGGRPGPGEREVGSGDSEAEALPYPALAPVVFFYLSQESRPRSWCLRLVCNPWFERVSMLVILLNCVTLGMFHPCEDIACDSPRCRILQSFDDFIFAFFAVEMIVKMIALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLPENFSIPYTVDLERYYQTENEDENPFICSQPRENGMRYCRSIPTRREEGLECTLDYYSYNDTTNTSCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMKEQRVRYLSNASTLASFSEPGSCYDELLKYLVYIARKGSKQLVELYRVAGVRMGFLASPASKVERHAGKRRSRRRSSVHHLIHHHHHHHHHYHLGNGNLRAPRASPEISDVDTGSLHNGTNRLMLPPSAPNPHMAPTATASGTESVHSIYHADCHVEPLRCRVALPQPSPEDIPRSVVMGSKVYPTVHPSTSHEVRKEKSLGEEAMGAGSSTLSGLNIPPGPYSTMHKLLETQSTGFLSVHVTDKGDGFRGPCPSSCKIASPCTKLDGGSRSPESCPYCLKALANEAEQTDNETDSDSEGVYEFTQDAHYSDQRDPQRGRAWARSSSRVLAFWRVVCETFQKIVDSKYFGRGIMVAILINTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKVLVYGPFGYIKNPYNIFDGIIVVISVWEIVGQQGGGLSVLRTFRLMRVLKLVRFMPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQTEGDASKSDSEGELFLRSLEEEGGLKKNLSNPVLMALSEHPELKKSLTPPLIIHTAATPMPMPKSAMFGDAAQGYESRRASGVSMDPAAYELKSPPSTRSSPHSPWSAGSSWPSRRSSWNSIGRAPSLKRRGQSSERRSLLSGEGKESSEDGESSDEERSSRAGSVNGSLPHRMESLEAKGSFDLQDTLQVPSLYRTSSMHSSRTSTSEHQDCNGKTSPGLLVHQLHLDDPRPDCDDADDEGNMSKRDRMKAWVRAHLPTCCKERDSWSIYVFAPHSRFRLMCNKIITHKMFDHIVLVIIFLNCITIAMERPKIEPHSAERIFLTLSNYIFTVIFLTEMTVKVVALGLCFGEKAYLKSSWNVLDGVLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFICQGEDTRNITNKSDCAEASYKWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPVMNYNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEAKRREEKRLRRLEKKRRSKEKQMAEAQCKPYYSDYSRFRFLIHQMCTSHYLDLFITGVIGLNVITMAMEHYQQPKVLDEALKICNYIFTVIFVLESVSKLIAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDDTHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELEMEMKTISPGQHSPSDIFTWMGGVGGERPESPRGCPHPLQIQERHLFDTISLLIQESLEGELKLMDNLSGSVCHHYALPAPEYYSSENQAELRCRDAALALSPCQDLLSVRKPSVGRTHSLPNDSYMFHTSQPRSRPSTASLRDGNPAQHKVHSGSKASVQSQPADTSSLLQIPKDHFHHMRAHDPLVRESKAPAAAPVHSPSAERLLRRQMAIRNDSSDSKENLHAELSELPNPDIPSAPQEESAAALTPSEGEDLAAWSRASVHTQHHSHNQYNVSKQAPASCACADSYQETPGDSMDQEVSETNSSLEPFPSETCTASSACSEAQPLTPKRNIGSTGSVTLKDLKKYHSVDTQGLLKKPPSWLDDQRRHSIEICSMENSPQHHSTSSSSGFISQVVSEMEGLQGTRQKKKLSPPCISIDPPSEQGLLPRGPHSVSPARGDTCLRRRAPSCDSKDSVDIGDSLLPDSMSASPTPKKDLLTLPSFSFDQNEVEP", "length": 2347, "header": "tr|A0A8V1AKA8-1|A0A8V1AKA8_CHICK Isoform 1 of Voltage-dependent T-type calcium channel subunit alpha-1G OS=Gallus gallus OX=9031 GN=CACNA1G PE=3 SV=1 CANONICAL=A0A8V1AKA8-1" }, "locus": { "chromosome": "18", "start_pos": 10930511, "end_pos": 10825872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071901.1", "url": "https://www.ensembl.org/id/ENSGALT00010071901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044591.1", "url": "https://www.ensembl.org/id/ENSGALP00010044591.1" } ] } }, { "isoform_ac": "A0A8V1ANI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8/entry#A0A8V1ANI6-1", "sequence": { "sequence": "MDEDGPRAADEEPEPGRAKTFIRLNDLSGAGGRPGPGEREVGSGDSEAEALPYPALAPVVFFYLSQESRPRSWCLRLVCNPWFERVSMLVILLNCVTLGMFHPCEDIACDSPRCRILQSFDDFIFAFFAVEMIVKMIALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLPENFSIPYTVDLERYYQTENEDENPFICSQPRENGMRYCRSIPTRREEGLECTLDYYSYNDTTNTSCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMKEQRVRYLSNASTLASFSEPGSCYDELLKYLVYIARKGSKQLVELYRVAGVRMGFLASPASKVERHAGKRRSRRRSSVHHLIHHHHHHHHHYHLGNGNLRAPRASPEISDVDTGSLHNGTNRLMLPPSAPNPHMAPTATASGTESVHSIYHADCHVEPLRCRVALPQPSPEDIPRSVVMGSKVYPTVHPSTSHEVRKEKSLGEEAMGAGSSTLSGLNIPPGPYSTMHKLLETQSTGFLSVHVTDKGDGFRGPCPSSCKIASPCTKLDGGSRSPESCPYCLKALANEAEQTDNETDSDSEGVYEFTQDAHYSDQRDPQRGRAWARSSSRVLAFWRVVCETFQKIVDSKYFGRGIMVAILINTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKVLVYGPFGYIKNPYNIFDGIIVVISVWEIVGQQGGGLSVLRTFRLMRVLKLVRFMPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQTEEISKREDAGGQLSCIQLPGDSAAGDASKSDSEGELFLRSLEEEGGLKKNLSNPVLMALSEHPELKKSLTPPLIIHTAATPMPMPKSAMFGDAAQGYESRRASGVSMDPAAYELKSPPSTRSSPHSPWSAGSSWPSRRSSWNSIGRAPSLKRRGQSSERRSLLSGEGKESSEDGESSDEERSSRAGSVNGSLPHRMESLEAKGSFDLQDTLQVPSLYRTSSMHSSRTSTSEHQDCNGKTSPGLLVHQLHLDDPRPDCDDADDEGNMSKRDRMKAWVRAHLPTCCKERDSWSIYVFAPHSRFRLMCNKIITHKMFDHIVLVIIFLNCITIAMERPKIEPHSAERIFLTLSNYIFTVIFLTEMTVKVVALGLCFGEKAYLKSSWNVLDGVLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFICQGEDTRNITNKSDCAEASYKWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPVMNYNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEAKRREEKRLRRLEKKRRNLMLDDVLMESTASVVPEAQCKPYYSDYSRFRFLIHQMCTSHYLDLFITGVIGLNVITMAMEHYQQPKVLDEALKICNYIFTVIFVLESVSKLIAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDDTHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELEMEMKTISPGQHSPSDIFTWMGGVGGERPESPRGCPHPLQIQAELRCRDAALALSPCQDLLSVRKPSVGRTHSLPNDSYMFHTSQPRSRPSTASLRDGNPAQHKVHSGSKASVQSQPADTSSLLQIPKDHFHHMRAHDPLVRESKAPAAAPVHSPSAERLLRRQMAIRNDSSDSKENLHAELSELPNPDIPSAPQEESAAALTPSEGEDLAAWSRASVHTQHHSHNQYNVSKQAPASCACADSYQETPGDSMDQEVSETNSSLEPFPSETCTASSACSEAQPLTPKRNIGSTGSVTLKDLKKYHSVDTQGLLKKPPSWLDDQRRHSIEICSMENSPQHHSTSSSSGFISQVVSEMEGLQGTRQKKKLSPPCISIDPPSEQGLLPRGPHSVSPARGDTCLRRRAPSCDSKDSVDIGDSLLPDSMSASPTPKKDLLTLPSFSFDQNEVEP", "length": 2333, "header": "tr|A0A8V1ANI6-1|A0A8V1AKA8_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha-1G OS=Gallus gallus OX=9031 GN=CACNA1G PE=3 SV=1 CANONICAL=A0A8V1AKA8-1" }, "locus": { "chromosome": "18", "start_pos": 10930511, "end_pos": 10825872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071902.1", "url": "https://www.ensembl.org/id/ENSGALT00010071902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044592.1", "url": "https://www.ensembl.org/id/ENSGALP00010044592.1" } ] } }, { "isoform_ac": "A0A8V1APY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8/entry#A0A8V1APY2-1", "sequence": { "sequence": "MKLPWAGARAHSLQSFDDFIFAFFAVEMIVKMIALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLPENFSIPYTVDLERYYQTENEDENPFICSQPRENGMRYCRSIPTRREEGLECTLDYYSYNDTTNTSCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIMYFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMKEQRVRYLSNASTLASFSEPGSCYDELLKYLVYIARKGSKQLVELYRVAGVRMGFLASPASKVERHAGKRRSRRRSSVHHLIHHHHHHHHHYHLGNGNLRAPRASPEISDVDTGSLHNGTNRLMLPPSAPNPHMAPTATASGTESVHSIYHADCHVEPLRCRVALPQPSPEDIPRSVVMGSKVYPTVHPSTSHEVRKEKSLGEEAMGAGSSTLSGLNIPPGPYSTMHKLLETQSTGFLSVHVTDKGDGFRGPCPSSCKIASPCTKLDGGSRSPESCPYCLKALANEAEQTDNETDSDSEGVYEFTQDAHYSDQRDPQRGRAWARSSSRVLAFWRVVCETFQKIVDSKYFGRGIMVAILINTLSMGIEYHEQPEELTNALEISNIVFTSLFALEMLLKVLVYGPFGYIKNPYNIFDGIIVVISVWEIVGQQGGGLSVLRTFRLMRVLKLVRFMPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTLPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLVAILVEGFQTEGDASKSDSEGELFLRSLEEEGGLKKNLSNPVLMALSEHPELKKSLTPPLIIHTAATPMPMPKSAMFGDAAQGYESRRASGVSMDPAAYELKSPPSTRSSPHSPWSAGSSWPSRRSSWNSIGRAPSLKRRGQSSERRSLLSGEGKESSEDGESSDEERSSRAGSVNGSLPHRMESLEAKGSFDLQDTLQVPSLYRTSSMHSSRTSTSEHQDCNGKTSPGLLVHQLHLDDPRPDCDDADDEGNMSKRDRMKAWVRAHLPTCCKERDSWSIYVFAPHSRFRLMCNKIITHKMFDHIVLVIIFLNCITIAMERPKIEPHSAERIFLTLSNYIFTVIFLTEMTVKVVALGLCFGEKAYLKSSWNVLDGVLVLISVIDILVSMVSDSGTKILGMLRVLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFICQGEDTRNITNKSDCAEASYKWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPVMNYNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEAKRREEKRLRRLEKKRRSKEKQMADLMLDDVLMESTASVVPEAQCKPYYSDYSRFRFLIHQMCTSHYLDLFITGVIGLNVITMAMEHYQQPKVLDEALKICNYIFTVIFVLESVSKLIAFGFRRFFQDRWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDDTHPCEGLGRHATFRNFGMAFLTLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKEAKEEAELEAELEMEMKTISPGQHSPSDIFTWMGGVGGERPESPRGCPHPLQIQAELRCRDAALALSPCQDLLSVRKPSVGRTHSLPNDSYMFHTSQPRSRPSTASLRDGNPAQHKVHSGSKASVQSQPADTSSLLQIPKDHFHHMRAHDPLVRESKAPAAAPVHSPSAERLLRRQMAIRNDSSDSKENLHAELSELPNPDIPSAPQEESAAALTPSEGEDLAAWSRASVHTQHHSHNQYNVSKQAPASCACADSYQETPGDSMDQEVSETNSSLEPFPSETCTASSACSEAQPLTPKRNIGSTGSVTLKDLKKYHSVDTQGLLKKPPSWLDDQRRHSIEICSMENSPQHHSTSSSSGFISQVVSEMEGLQGTRQKKKLSPPCISIDPPSEQGLLPRGPHSVSPARGDTCLRRRAPSCDSKDSVDIGDSLLPDSMSASPTPKKDLLTLPSFSFDQNEVEP", "length": 2213, "header": "tr|A0A8V1APY2-1|A0A8V1AKA8_CHICK Computationally mapped isoform of Voltage-dependent T-type calcium channel subunit alpha-1G OS=Gallus gallus OX=9031 GN=CACNA1G PE=3 SV=1 CANONICAL=A0A8V1AKA8-1" }, "locus": { "chromosome": "18", "start_pos": 10915433, "end_pos": 10825872, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071900.1", "url": "https://www.ensembl.org/id/ENSGALT00010071900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044590.1", "url": "https://www.ensembl.org/id/ENSGALP00010044590.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 303, "start_aa": "Asn", "end_pos": 303, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn303", "evidence": [ { "id": "A0A8V1ANI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI6#ptm_processing" }, { "id": "PIRSR602077-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-3" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "voltage-gated sodium channel complex", "id": "GO:0001518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "calcium ion import", "id": "GO:0070509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "membrane depolarization during action potential", "id": "GO:0086010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "positive regulation of calcium ion-dependent exocytosis", "id": "GO:0045956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "low voltage-gated calcium channel activity", "id": "GO:0008332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" }, { "name": "voltage-gated sodium channel activity", "id": "GO:0005248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005248", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1006, "end_pos": 1008, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1145, "end_pos": 1147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1221, "end_pos": 1223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1440, "end_pos": 1442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1443, "end_pos": 1445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1679, "end_pos": 1681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1919, "end_pos": 1921, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1975, "end_pos": 1977, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2068, "end_pos": 2070, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2128, "end_pos": 2130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2159, "end_pos": 2161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA8" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 402, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "Asn303" } ], "binding_sites": [ { "evidence": [ { "id": "A0A8V1APY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY2#function" }, { "id": "A0A8V1APY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY2" }, { "id": "PIRSR602077-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 1374, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29108", "ligand": "Ca(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 1374, "end_pos": 1374, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ANI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI6#function" }, { "id": "A0A8V1ANI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI6" }, { "id": "PIRSR602077-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR602077-1" } ], "binding_site_uniprot": 1501, "amino_acid": 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"MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQVQQSDNPEETWNITVPGGQHSVNVTGLKANTPYNVTLYGVIRGYRTKPLYVETTTGAHPEVGELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTVEEPLLSKLTVSNATSDSMLLMWEARDNAFDHFILEVRNSDSPLDSLVQIVPGASRHYVVTNLKAATNYTVQLHGVVDGQGGQTLTALATTEAEPQLGTLTLTNVTPDSFNLSWTTRDGPFAKFVIHVRDSFAAHEPQELTVSGGARSAHISGLLDYTGYDINIKGTTDAGVHTEPLTAFVMTEAMPPLENLTVSDINPYGFTVSWMASENAFDSFLVVVVDSGKLLDPQEFLLTGAQRQLKLKGLITGIGYEVMLYGFAKGHQTKPLSTVAVTEAEPEVDNLLVSDATPDGFRLSWTADDGVFDSFVLKIRDTKRKSDPLELIVPGHERTHDITGLKEGTEYEIELYGVSSGRRSQPINSVATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 2082, "header": "tr|A0A8V1AI29-1|A0A8V1AI29_CHICK Isoform 1 of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29/entry#A0A8V1AAN6-1", "sequence": { "sequence": "MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQVQQSDNPEETWNITVPGGQHSVNVTGLKANTPYNVTLYGVIRGYRTKPLYVETTTGAHPEVGELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTVEEPLLSKLTVSNATSDSMLLMWEARDNAFDHFILEVRNSDSPLDSLVQIVPGASRHYVVTNLKAATNYTVQLHGVVDGQGGQTLTALATTEAMPPLENLTVSDINPYGFTVSWMASENAFDSFLVVVVDSGKLLDPQEFLLTGAQRQLKLKGLITGIGYEVMLYGFAKGHQTKPLSTVAVTEAEPEVDNLLVSDATPDGFRLSWTADDGVFDSFVLKIRDTKRKSDPLELIVPGHERTHDITGLKEGTEYEIELYGVSSGRRSQPINSVATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 1990, "header": "tr|A0A8V1AAN6-1|A0A8V1AAN6_CHICK Computationally mapped isoform of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "locus": { "chromosome": "17", "start_pos": 3362764, "end_pos": 3322027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069918.1", "url": "https://www.ensembl.org/id/ENSGALT00010069918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043044.1", "url": "https://www.ensembl.org/id/ENSGALP00010043044.1" } ] } }, { "isoform_ac": "A0A8V1AAP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29/entry#A0A8V1AAP4-1", "sequence": { "sequence": "MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 1535, "header": "tr|A0A8V1AAP4-1|A0A8V1AAP4_CHICK Computationally mapped isoform of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "locus": { "chromosome": "17", "start_pos": 3362764, "end_pos": 3322027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069923.1", "url": "https://www.ensembl.org/id/ENSGALT00010069923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043049.1", "url": "https://www.ensembl.org/id/ENSGALP00010043049.1" } ] } }, { "isoform_ac": "A0A8V1AG10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29/entry#A0A8V1AG10-1", "sequence": { "sequence": "MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQVQQSDNPEETWNITVPGGQHSVNVTGLKANTPYNVTLYGVIRGYRTKPLYVETTTGAHPEVGELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTEAMPPLENLTVSDINPYGFTVSWMASENAFDSFLVVVVDSGKLLDPQEFLLTGAQRQLKLKGLITGIGYEVMLYGFAKGHQTKPLSTVAVTEAEPEVDNLLVSDATPDGFRLSWTADDGVFDSFVLKIRDTKRKSDPLELIVPGHERTHDITGLKEGTEYEIELYGVSSGRRSQPINSVATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 1899, "header": "tr|A0A8V1AG10-1|A0A8V1AI29_CHICK Computationally mapped isoform of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "locus": { "chromosome": "17", "start_pos": 3362764, "end_pos": 3322027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069920.1", "url": "https://www.ensembl.org/id/ENSGALT00010069920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043046.1", "url": "https://www.ensembl.org/id/ENSGALP00010043046.1" } ] } }, { "isoform_ac": "A0A8V1AI29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29/entry#A0A8V1AI29-1", "sequence": { "sequence": "MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQVQQSDNPEETWNITVPGGQHSVNVTGLKANTPYNVTLYGVIRGYRTKPLYVETTTGAHPEVGELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTVEEPLLSKLTVSNATSDSMLLMWEARDNAFDHFILEVRNSDSPLDSLVQIVPGASRHYVVTNLKAATNYTVQLHGVVDGQGGQTLTALATTEAEPQLGTLTLTNVTPDSFNLSWTTRDGPFAKFVIHVRDSFAAHEPQELTVSGGARSAHISGLLDYTGYDINIKGTTDAGVHTEPLTAFVMTEAMPPLENLTVSDINPYGFTVSWMASENAFDSFLVVVVDSGKLLDPQEFLLTGAQRQLKLKGLITGIGYEVMLYGFAKGHQTKPLSTVAVTEAEPEVDNLLVSDATPDGFRLSWTADDGVFDSFVLKIRDTKRKSDPLELIVPGHERTHDITGLKEGTEYEIELYGVSSGRRSQPINSVATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 2082, "header": "tr|A0A8V1AI29-1|A0A8V1AI29_CHICK Isoform 1 of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "locus": { "chromosome": "17", "start_pos": 3362764, "end_pos": 3322027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069917.1", "url": "https://www.ensembl.org/id/ENSGALT00010069917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043043.1", "url": "https://www.ensembl.org/id/ENSGALP00010043043.1" } ] } }, { "isoform_ac": "A0A8V1AI36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29/entry#A0A8V1AI36-1", "sequence": { "sequence": "MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTEAEPEVDNLLVSDATPDGFRLSWTADDGVFDSFVLKIRDTKRKSDPLELIVPGHERTHDITGLKEGTEYEIELYGVSSGRRSQPINSVATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 1626, "header": "tr|A0A8V1AI36-1|A0A8V1AI36_CHICK Computationally mapped isoform of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "locus": { "chromosome": "17", "start_pos": 3362764, "end_pos": 3322027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069922.1", "url": "https://www.ensembl.org/id/ENSGALT00010069922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043048.1", "url": "https://www.ensembl.org/id/ENSGALP00010043048.1" } ] } }, { "isoform_ac": "A0A8V1AKA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29/entry#A0A8V1AKA6-1", "sequence": { "sequence": "MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQVQQSDNPEETWNITVPGGQHSVNVTGLKANTPYNVTLYGVIRGYRTKPLYVETTTGAHPEVGELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 1717, "header": "tr|A0A8V1AKA6-1|A0A8V1AKA6_CHICK Computationally mapped isoform of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "locus": { "chromosome": "17", "start_pos": 3362764, "end_pos": 3322027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069921.1", "url": "https://www.ensembl.org/id/ENSGALT00010069921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043047.1", "url": "https://www.ensembl.org/id/ENSGALP00010043047.1" } ] } }, { "isoform_ac": "A0A8V1AM22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29/entry#A0A8V1AM22-1", "sequence": { "sequence": "MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGRCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTAHLVTTSGQPDSATSFNATSPAPTELSHLANPSTGPHALHSVPTDLPISEVTDALRDLNITHRTFSSFTLSWAAQDEVFDQFLITLKDLSSLNRTQEIFLLGNQRETEITNLTAGTQYQINLRGSTQGQLSWALETLAATEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQVQQSDNPEETWNITVPGGQHSVNVTGLKANTPYNVTLYGVIRGYRTKPLYVETTTGAHPEVGELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTEAEPEVDNLLVSDATPDGFRLSWTADDGVFDSFVLKIRDTKRKSDPLELIVPGHERTHDITGLKEGTEYEIELYGVSSGRRSQPINSVATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA", "length": 1948, "header": "tr|A0A8V1AM22-1|A0A8V1AI29_CHICK Computationally mapped isoform of Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=3 SV=1 CANONICAL=A0A8V1AI29-1" }, "locus": { "chromosome": "17", "start_pos": 3362764, "end_pos": 3322027, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069919.1", "url": "https://www.ensembl.org/id/ENSGALT00010069919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043045.1", "url": "https://www.ensembl.org/id/ENSGALP00010043045.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-216083", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" }, { "id": "R-GGA-3000178", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3000178", "resource": "Reactome", "description": "ECM proteoglycans" }, { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "regulation of cell growth", "id": "GO:0001558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001558", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "syndecan binding", "id": "GO:0045545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045545", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" }, { "name": "perisynaptic extracellular matrix", "id": "GO:0098966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1050, "end_pos": 1052, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1090, "end_pos": 1092, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1112, "end_pos": 1114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1153, "end_pos": 1155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1183, "end_pos": 1185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1292, "end_pos": 1294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1328, "end_pos": 1330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1335, "end_pos": 1337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1415, "end_pos": 1417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1690, "end_pos": 1692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2010, "end_pos": 2012, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2043, "end_pos": 2045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AI29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 312, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AI29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 1856, "end_pos": 2071, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AI29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI29" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 595, "end_pos": 685, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1050, "end_pos": 1052 }, { "start_pos": 1090, "end_pos": 1092 }, { "start_pos": 1101, "end_pos": 1103 }, { "start_pos": 1112, "end_pos": 1114 }, { "start_pos": 1153, "end_pos": 1155 }, { "start_pos": 1183, "end_pos": 1185 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1292, "end_pos": 1294 }, { "start_pos": 1328, "end_pos": 1330 }, { "start_pos": 1335, "end_pos": 1337 }, { "start_pos": 1415, "end_pos": 1417 }, { "start_pos": 168, "end_pos": 170 }, { 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"common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCPEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ84", "locus": { "chromosome": "18", "start_pos": 6939460, "end_pos": 6916360, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029582", "url": "https://www.ensembl.org/id/ENSGALG00010029582" } ] } } ], "crossref": [ { "id": "A0A8V1AJ84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ84", "database": "AlphaFoldDB", "categories": [] }, { "id": "417403", "url": "https://www.ncbi.nlm.nih.gov/gene/417403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001563", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001563", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", 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GN=SCPEP1 PE=1 SV=1 CANONICAL=A0A8V1AJ84-1" }, "locus": { "chromosome": "18", "start_pos": 6936301, "end_pos": 6927009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071505.1", "url": "https://www.ensembl.org/id/ENSGALT00010071505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044195.1", "url": "https://www.ensembl.org/id/ENSGALP00010044195.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type carboxypeptidase activity", "id": "GO:0004185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004185", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 381, "end_pos": 383 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ] }, { "name": "ZNF207", "type": "synonym", "evidence": [ { "id": "XP_003642366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642366" } ] } ], "protein_names": [ { "name": "BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003642366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642366" } ] }, { "name": "Zinc finger protein 207", "type": "synonym", "evidence": [ { "id": "A0A8V1AJG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_003642366.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642366" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF207", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1", "locus": { "chromosome": "18", "start_pos": 7377315, "end_pos": 7364530, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029607", "url": "https://www.ensembl.org/id/ENSGALG00010029607" } ] } } ], "crossref": [ { "id": "A0A8V1AJG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003454", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003454", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20908", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20908", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417413", "url": "https://www.ncbi.nlm.nih.gov/gene/417413", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417413", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417413", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KQVLRPW", "url": "https://omabrowser.org/oma/group/KQVLRPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PN34", "url": "https://www.orthodb.org/?gene=A0A1D5PN34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJG1", "url": "https://www.orthodb.org/?gene=A0A8V1AJG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APG1", "url": "https://www.orthodb.org/?gene=A0A8V1APG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23215:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23215:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003642366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PN34", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PN34-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMEERRRLLEQKTQAESQKKKQQDDSDEYEDDESAASTSFQPQQVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMAGVPPMMPGMPPVMPGMPPGLHQQRKYMQSFCGGNMMMPMGGMMPPGPGIPPLMPGMPPGMPPPVGPRPGMPPMTQAQPATAPGILNRPPAPAASAPTPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSNALFPSTAQAAAAVQGPVGTDFKPLNSTATTTEPPKPTFPAYTQSTTSTTSTTNSTAAKPATSITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQASLGNPPVGPIGGMMPPQPGIPPQQQGMRPPMPPHGQYGAHHQGMPGYLPGAMPPYGQGPPMVPPYQSGPPRPPMGMRPPVMSQGGRY", "length": 496, "header": "tr|A0A8V1AJG1-1|A0A8V1AJG1_CHICK Isoform 1 of Zinc finger protein 207 OS=Gallus gallus OX=9031 GN=ZNF207 PE=1 SV=1 CANONICAL=A0A8V1AJG1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PN34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1/entry#A0A1D5PN34-1", "sequence": { "sequence": "MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMEERRRLLEQKTQESQKKKQQDDSDEYEDDESAASTSFQPQQVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMAGVPPMMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVGPRPGMPPMTQAQPATAPGILNRPPAPAASAPTPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSNALFPSTAQAAAAVQGPVGTDFKPLNSTATTTEPPKPTFPAYTQSTTSTTSTTNSTAAKPATSITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQASLGNPPVGPIGGMMPPQPGIPPQQQGMRPPMPPHGQYGAHHQGMPGYLPGAMPPYGQGPPMVPPYQSGPPRPPMGMRPPVMSQGGRY", "length": 479, "header": "tr|A0A1D5PN34-1|A0A8V1AJG1_CHICK Computationally mapped isoform of Zinc finger protein 207 OS=Gallus gallus OX=9031 GN=ZNF207 PE=1 SV=1 CANONICAL=A0A8V1AJG1-1" }, "locus": { "chromosome": "18", "start_pos": 7376713, "end_pos": 7365800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071584.1", "url": "https://www.ensembl.org/id/ENSGALT00010071584.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044274.1", "url": "https://www.ensembl.org/id/ENSGALP00010044274.1" } ] } }, { "isoform_ac": "A0A8V1AJG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1/entry#A0A8V1AJG1-1", "sequence": { "sequence": "MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMEERRRLLEQKTQAESQKKKQQDDSDEYEDDESAASTSFQPQQVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMAGVPPMMPGMPPVMPGMPPGLHQQRKYMQSFCGGNMMMPMGGMMPPGPGIPPLMPGMPPGMPPPVGPRPGMPPMTQAQPATAPGILNRPPAPAASAPTPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSNALFPSTAQAAAAVQGPVGTDFKPLNSTATTTEPPKPTFPAYTQSTTSTTSTTNSTAAKPATSITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQASLGNPPVGPIGGMMPPQPGIPPQQQGMRPPMPPHGQYGAHHQGMPGYLPGAMPPYGQGPPMVPPYQSGPPRPPMGMRPPVMSQGGRY", "length": 496, "header": "tr|A0A8V1AJG1-1|A0A8V1AJG1_CHICK Isoform 1 of Zinc finger protein 207 OS=Gallus gallus OX=9031 GN=ZNF207 PE=1 SV=1 CANONICAL=A0A8V1AJG1-1" }, "locus": { "chromosome": "18", "start_pos": 7376713, "end_pos": 7365800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071583.1", "url": "https://www.ensembl.org/id/ENSGALT00010071583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044273.1", "url": "https://www.ensembl.org/id/ENSGALP00010044273.1" } ] } }, { "isoform_ac": "A0A8V1APG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1/entry#A0A8V1APG1-1", "sequence": { "sequence": "MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMEERRRLLEQKTQAESQKKKQQDDSDEYEDDESAASTSFQPQQVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMAGVPPMMPGMPPVMPGMPPGLHQQRKYMQSFCGGNMMMPMGGMMPPGPGIPPLMPGMPPGMPPPVGPRPGMPPMTQAQPATAPGILNRPPAPAASAPTPQPPVTKPLFPSAGQAAAAVQGPVGTDFKPLNSTATTTEPPKPTFPAYTQSTTSTTSTTNSTAAKPATSITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQASLGNPPVGPIGGMMPPQPGIPPQQQGMRPPMPPHGQYGAHHQGMPGYLPGAMPPYGQGPPMVPPYQSGPPRPPMGMRPPVMSQGGRY", "length": 465, "header": "tr|A0A8V1APG1-1|A0A8V1APG1_CHICK Computationally mapped isoform of Zinc finger protein 207 OS=Gallus gallus OX=9031 GN=ZNF207 PE=1 SV=1 CANONICAL=A0A8V1AJG1-1" }, "locus": { "chromosome": "18", "start_pos": 7376713, "end_pos": 7365800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071582.1", "url": "https://www.ensembl.org/id/ENSGALT00010071582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044272.1", "url": "https://www.ensembl.org/id/ENSGALP00010044272.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417413", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417413", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O43670-1", "protein_name": "BUB3-interacting and GLEBS motif-containing protein ZNF207", "gene_name": "ZNF207", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY", "length": 478 }, "evidence": [ { "id": "A0A8V1AJG1", "url": "https://omabrowser.org/oma/group/A0A8V1AJG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JMD0-1", "protein_name": "BUB3-interacting and GLEBS motif-containing protein ZNF207", "gene_name": "Znf207", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKETIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDESAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAAVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPAATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQTPIGNPPVGPIGGMMPPQPGLPQQQAMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY", "length": 495 }, "evidence": [ { "id": "A0A8V1AJG1", "url": "https://omabrowser.org/oma/group/A0A8V1AJG1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" }, { "name": "spindle matrix", "id": "GO:1990047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990047", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" }, { "name": "mitotic spindle assembly", "id": "GO:0090307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG1" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 34, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 263 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 326, "end_pos": 328 }, { "start_pos": 354, "end_pos": 356 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIA0-1", "uniprot_ac": "A0A8V1AIA0", "uniprot_id": "A0A8V1AIA0_CHICK", "mass": { "chemical_mass": 82367.0, "monoisotopic_mass": 82367.0 }, "refseq": { "ac": "XP_040509449", "name": "heterogeneous nuclear ribonucleoprotein M isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509449" }, "gene_names": [ { "name": "HNRNPM", "type": "recommended", "evidence": [ { "id": "A0A8V1AIA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ] }, { "name": "HNRNPM", "type": "synonym", "evidence": [ { "id": "XP_040509449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509449" } ] }, { "name": "HNRPM", "type": "synonym", "evidence": [ { "id": "XP_040509449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509449" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein M", "type": "recommended", "evidence": [ { "id": "A0A8V1AIA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein M isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040509449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509449" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509449" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HNRNPM", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0", "locus": { "chromosome": "28", "start_pos": 922274, "end_pos": 948046, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028328", "url": "https://www.ensembl.org/id/ENSGALG00010028328" } ] } } ], "crossref": [ { "id": "A0A8V1AIA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12657", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12657", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12659", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12659", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420054", "url": "https://www.ncbi.nlm.nih.gov/gene/420054", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFZ6", "url": "https://www.orthodb.org/?gene=A0A8V1AFZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG01", "url": "https://www.orthodb.org/?gene=A0A8V1AG01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIA0", "url": "https://www.orthodb.org/?gene=A0A8V1AIA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040509449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509449", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAVAAATESAGGKMEEPPAAAAPPPPNGAGGAGDPPAKSEGERPSQNEKRKEKSVKRGGNRFEPYANPAKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLGGRPLKVKELRTCSYIKGPIKQKSRETSSVLTVTLGRRDPDGEHARRAMQKVMAAGGMGIGPGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGAVVRADILEDKDGKSRGIGTVTFEQAIEAVQAISMFNGQLLFDRPMHVKMDERAFPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGMGMGNMGPGGMGMEGMGFGMNKMGGMEGPFGGMENIGRFPAGMNMGRMSEMDRAMGGGFEREFGRNEMGMSRSFGETLERGIGGGNASIPGIERMAPGIDRMGSGIERIPSGMGHGMERVGSEIDRMGLVLDRMSSNVDRIGSGIDRMAPLGIDHIAPNIERMGPAIERMGSGIERMGSGIGFGIERMGAAIDRVGTTMDRMGSGVERMGSGMDRMGIGMERMVPAGMGTGMGQVIERMPAGLDRIGATPMERIGIDRMGAASMERMGLERIGATNMERMGPAMGQGMGAGIDRMGLAMGSNFERTMEMERGNFAGNFAGSLGGTGGPAAGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVRFESPEVAERACRMMNGIQLRGREIDVRIDRNA", "length": 772, "header": "tr|A0A8V1AIA0-1|A0A8V1AIA0_CHICK Isoform 1 of Heterogeneous nuclear ribonucleoprotein M OS=Gallus gallus OX=9031 GN=HNRNPM PE=1 SV=1 CANONICAL=A0A8V1AIA0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0/entry#A0A8V1AFZ6-1", "sequence": { "sequence": "QPGWGSDEGERPSQNEKRKEKSVKRGGNRFEPYANPAKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGNVVEFKMEESMKKAAEVLNKHSLGGRPLKVKEDPDGEHARRAMQKVMAAGGMGIGPGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGAVVRADILEDKDGKSRGIGTVTFEQAIEAVQAISMFNGQLLFDRPMHVKMDERAFPKGDFFPPERPQQLPRMGMEGMGFGMNKMGGMEGPFGGMENIGRFPAGMNMGRMSEMDRAMGGGFEREFGRNEMGMSRSFGETLERGIGGGNASIPGIERMAPGIDRMGSGIERIPSGMGHGMERVGSEIDRMGLVLDRMSSNVDRIGSGIDRMAPLGIDHIAPNIERMGPAIERMGSGIERMGSGIGFGIERMGAAIDRVGTTMDRMGSGVERMGSGMDRMGIGMERMVPAGMGTGMGQVIERMPAGLDRIGATPMERIGIDRMGAASMERMGLERIGATNMERMGPAMGQGMGAGIDRMGLAMGSNFERTMEMERGNFAGNFAGSLGGTGGPAAGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVRFESPEVAERACRMMNGIQLRGREIDVRIDRNA", "length": 668, "header": "tr|A0A8V1AFZ6-1|A0A8V1AIA0_CHICK Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M OS=Gallus gallus OX=9031 GN=HNRNPM PE=1 SV=1 CANONICAL=A0A8V1AIA0-1" }, "locus": { "chromosome": "28", "start_pos": 945522, "end_pos": 922905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068594.1", "url": "https://www.ensembl.org/id/ENSGALT00010068594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042181.1", "url": "https://www.ensembl.org/id/ENSGALP00010042181.1" } ] } }, { "isoform_ac": "A0A8V1AG01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0/entry#A0A8V1AG01-1", "sequence": { "sequence": "MAAAAAVAAATESAGGKMEEPPAAAAPPPPNGAGGAGDPPAKSEGERPSQNEKRKEKSVKRGGNRFEPYANPAKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLGGRPLKVKELRTCSYIKGPIKQKSRETSSVLTVTLGRRDPDGEHARRAMQKVMAAGGMGIGPGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGAVVRADILEDKDGKSRGIGTVTFEQAIEAVQAISMFNGQLLFDRPMHVKMDERAFPKGDFFPPERPQQLPRMGMEGMGFGMNKMGGMEGPFGGMENIGRFPAGMNMGRMSEMDRAMGGGFEREFGRNEMGMSRSFGETLERGIGGGNASIPGIERMAPGIDRMGSGIERIPSGMGHGMERVGSEIDRMGLVLDRMSSNVDRIGSGIDRMAPLGIDHIAPNIERMGPAIERMGSGIERMGSGIGFGIERMGAAIDRVGTTMDRMGSGVERMGSGMDRMGIGMERMVPAGMGTGMGQVIERMPAGLDRIGATPMERIGIDRMGAASMERMGLERIGATNMERMGPAMGQGMGAGIDRMGLAMGSNFERTMEMERGNFAGNFAGSLGGTGGPAAGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVRFESPEVAERACRMMNGIQLRGREIDVRIDRNA", "length": 738, "header": "tr|A0A8V1AG01-1|A0A8V1AIA0_CHICK Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M OS=Gallus gallus OX=9031 GN=HNRNPM PE=1 SV=1 CANONICAL=A0A8V1AIA0-1" }, "locus": { "chromosome": "28", "start_pos": 947970, "end_pos": 922905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068601.1", "url": "https://www.ensembl.org/id/ENSGALT00010068601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042186.1", "url": "https://www.ensembl.org/id/ENSGALP00010042186.1" } ] } }, { "isoform_ac": "A0A8V1AIA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0/entry#A0A8V1AIA0-1", "sequence": { "sequence": "MAAAAAVAAATESAGGKMEEPPAAAAPPPPNGAGGAGDPPAKSEGERPSQNEKRKEKSVKRGGNRFEPYANPAKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLGGRPLKVKELRTCSYIKGPIKQKSRETSSVLTVTLGRRDPDGEHARRAMQKVMAAGGMGIGPGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGAVVRADILEDKDGKSRGIGTVTFEQAIEAVQAISMFNGQLLFDRPMHVKMDERAFPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGMGMGNMGPGGMGMEGMGFGMNKMGGMEGPFGGMENIGRFPAGMNMGRMSEMDRAMGGGFEREFGRNEMGMSRSFGETLERGIGGGNASIPGIERMAPGIDRMGSGIERIPSGMGHGMERVGSEIDRMGLVLDRMSSNVDRIGSGIDRMAPLGIDHIAPNIERMGPAIERMGSGIERMGSGIGFGIERMGAAIDRVGTTMDRMGSGVERMGSGMDRMGIGMERMVPAGMGTGMGQVIERMPAGLDRIGATPMERIGIDRMGAASMERMGLERIGATNMERMGPAMGQGMGAGIDRMGLAMGSNFERTMEMERGNFAGNFAGSLGGTGGPAAGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVRFESPEVAERACRMMNGIQLRGREIDVRIDRNA", "length": 772, "header": "tr|A0A8V1AIA0-1|A0A8V1AIA0_CHICK Isoform 1 of Heterogeneous nuclear ribonucleoprotein M OS=Gallus gallus OX=9031 GN=HNRNPM PE=1 SV=1 CANONICAL=A0A8V1AIA0-1" }, "locus": { "chromosome": "28", "start_pos": 947970, "end_pos": 922905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068600.1", "url": "https://www.ensembl.org/id/ENSGALT00010068600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042185.1", "url": "https://www.ensembl.org/id/ENSGALP00010042185.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "paraspeckles", "id": "GO:0042382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" } ], 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"glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGVPGGCPAPGPGWPWGDGGRWPQGSVAAGPVPARRGTAGHCSEKPRCSLRKGSALGPGDGALQISSPLNSKPCGRSPRFPLRSDPGVCHTAQSAAGRGQDMHRISCLLSGLAFILSATSTDSFARVGRRTCAAEPRSRTAAHTESHVQPVYLPYLTTCQGHRLCSTYRTIYKVAYRQVYKQVPQPVASCCPGWSRTSSYELSCNTALCQVPCQNGGRCSFPGRCACPPGWMGPSCQTDADECAGRSHGCSQLCINTAGSFHCACRDGFSLAADNKACQPVVPGPEPGTFSQADPSSEVKEEMKDLKNRVEALEQKLQLVLAPFHNLMPSAPEDVGTDPISRLSHSLQQLDRIDSLSEQISFLEERLETCSCRNEL", "length": 377, "header": "tr|A0A8V1AKE7-1|A0A8V1AKE7_CHICK Isoform 1 of EGF like domain multiple 7 OS=Gallus gallus OX=9031 GN=EGFL7 PE=1 SV=1 CANONICAL=A0A8V1AKE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7/entry#A0A8V1AAU0-1", "sequence": { "sequence": "MRGVPGGCPAPGPGWPWGDGGRWPQGSVAAGPVPARRGTAGHCSEKPRCSLRKGSALGPGDGALQISRRTCAAEPRSRTAAHTESHVQPVYLPYLTTCQGHRLCSTYRTIYKVAYRQVYKQVPQPVASCCPGWSRTSSYELSCNTALCQVPCQNGGRCSFPGRCACPPGWMGPSCQTDADECAGRSHGCSQLCINTAGSFHCACRDGFSLAADNKACQPVVPGPEPGTFSQADPSSEVKEEMKDLKNRVEALEQKLQLVLAPFHNLMPSAPEDVGTDPISRLSHSLQQLDRIDSLSEQISFLEERLETCSCRNEL", "length": 315, "header": "tr|A0A8V1AAU0-1|A0A8V1AAU0_CHICK Computationally mapped isoform of EGF like domain multiple 7 OS=Gallus gallus OX=9031 GN=EGFL7 PE=1 SV=1 CANONICAL=A0A8V1AKE7-1" }, "locus": { "chromosome": "17", "start_pos": 8366834, "end_pos": 8352550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069968.1", "url": "https://www.ensembl.org/id/ENSGALT00010069968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043094.1", "url": "https://www.ensembl.org/id/ENSGALP00010043094.1" } ] } }, { "isoform_ac": "A0A8V1AG57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7/entry#A0A8V1AG57-1", "sequence": { "sequence": "MRGVPGGCPAPGPGWPWGDGGRWPQGSVAAGPVPARRGTAGHCSEKPRCSLRKGSALGPGDGALQISSPLNSKPCGRSPRFPLRSDPGVCHTAQSAAGRGQDMHRISCLLSGLAFILSATSTDSFARVGTIYKVAYRQVYKQVPQPVASCCPGWSRTSSYELSCNTALCQVPCQNGGRCSFPGRCACPPGWMGPSCQTDADECAGRSHGCSQLCINTAGSFHCACRDGFSLAADNKACQPVVPGPEPGTFSQADPSSEVKEEMKDLKNRVEALEQKLQLVLAPFHNLMPSAPEDVGTDPISRLSHSLQQLDRIDSLSEQISFLEERLETCSCRNEL", "length": 336, "header": "tr|A0A8V1AG57-1|A0A8V1AKE7_CHICK Computationally mapped isoform of EGF like domain multiple 7 OS=Gallus gallus OX=9031 GN=EGFL7 PE=1 SV=1 CANONICAL=A0A8V1AKE7-1" }, "locus": { "chromosome": "17", "start_pos": 8366834, "end_pos": 8352550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069970.1", "url": "https://www.ensembl.org/id/ENSGALT00010069970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043096.1", "url": "https://www.ensembl.org/id/ENSGALP00010043096.1" } ] } }, { "isoform_ac": "A0A8V1AI82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7/entry#A0A8V1AI82-1", "sequence": { "sequence": "MHRISCLLSGLAFILSATSTDSFARVGRRTCAAEPRSRTAAHTESHVQPVYLPYLTTCQGHRLCSTYRTIYKVAYRQVYKQVPQPVASCCPGWSRTSSYELSCNTALCQVPCQNGGRCSFPGRCACPPGWMGPSCQTDADECAGRSHGCSQLCINTAGSFHCACRDGFSLAADNKACQPVVPGPEPGTFSQADPSSEVKEEMKDLKNRVEALEQKLQLVLAPFHNLMPSAPEDVGTDPISRLSHSLQQLDRIDSLSEQISFLEERLETCSCRNEL", "length": 275, "header": "tr|A0A8V1AI82-1|A0A8V1AI82_CHICK Computationally mapped isoform of EGF like domain multiple 7 OS=Gallus gallus OX=9031 GN=EGFL7 PE=1 SV=1 CANONICAL=A0A8V1AKE7-1" }, "locus": { "chromosome": "17", "start_pos": 8358941, "end_pos": 8352550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069967.1", "url": "https://www.ensembl.org/id/ENSGALT00010069967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043093.1", "url": "https://www.ensembl.org/id/ENSGALP00010043093.1" } ] } }, { "isoform_ac": "A0A8V1AKE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7/entry#A0A8V1AKE7-1", "sequence": { "sequence": "MRGVPGGCPAPGPGWPWGDGGRWPQGSVAAGPVPARRGTAGHCSEKPRCSLRKGSALGPGDGALQISSPLNSKPCGRSPRFPLRSDPGVCHTAQSAAGRGQDMHRISCLLSGLAFILSATSTDSFARVGRRTCAAEPRSRTAAHTESHVQPVYLPYLTTCQGHRLCSTYRTIYKVAYRQVYKQVPQPVASCCPGWSRTSSYELSCNTALCQVPCQNGGRCSFPGRCACPPGWMGPSCQTDADECAGRSHGCSQLCINTAGSFHCACRDGFSLAADNKACQPVVPGPEPGTFSQADPSSEVKEEMKDLKNRVEALEQKLQLVLAPFHNLMPSAPEDVGTDPISRLSHSLQQLDRIDSLSEQISFLEERLETCSCRNEL", "length": 377, "header": "tr|A0A8V1AKE7-1|A0A8V1AKE7_CHICK Isoform 1 of EGF like domain multiple 7 OS=Gallus gallus OX=9031 GN=EGFL7 PE=1 SV=1 CANONICAL=A0A8V1AKE7-1" }, "locus": { "chromosome": "17", "start_pos": 8366834, "end_pos": 8352550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069971.1", "url": "https://www.ensembl.org/id/ENSGALT00010069971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043097.1", "url": "https://www.ensembl.org/id/ENSGALP00010043097.1" } ] } }, { "isoform_ac": "A0A8V1AM60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7/entry#A0A8V1AM60-1", "sequence": { "sequence": "MGGWRPVATRQCGSGARPSAARDSGALQSSPLNSKPCGRSPRFPLRSDPGVCHTAQSAAGRGQDMHRISCLLSGLAFILSATSTDSFARVGRRTCAAEPRSRTAAHTESHVQPVYLPYLTTCQGHRLCSTYRTIYKVAYRQVYKQVPQPVASCCPGWSRTSSYELSCNTALCQVPCQNGGRCSFPGRCACPPGWMGPSCQTDADECAGRSHGCSQLCINTAGSFHCACRDGFSLAADNKACQPVVPGPEPGTFSQADPSSEVKEEMKDLKNRVEALEQKLQLVLAPFHNLMPSAPEDVGTDPISRLSHSLQQLDRIDSLSEQISFLEERLETCSCRNEL", "length": 339, "header": "tr|A0A8V1AM60-1|A0A8V1AM60_CHICK Computationally mapped isoform of EGF like domain multiple 7 OS=Gallus gallus OX=9031 GN=EGFL7 PE=1 SV=1 CANONICAL=A0A8V1AKE7-1" }, "locus": { "chromosome": "17", "start_pos": 8366787, "end_pos": 8352550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069969.1", "url": "https://www.ensembl.org/id/ENSGALT00010069969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043095.1", "url": "https://www.ensembl.org/id/ENSGALP00010043095.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417137", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417137", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 238, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AKE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE7" }, { "id": "PS51041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EMI", "eco_id": "ECO_0000259", "start_pos": 129, "end_pos": 207, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIB5-1", "uniprot_ac": "A0A8V1AIB5", "uniprot_id": "A0A8V1AIB5_CHICK", "mass": { "chemical_mass": 110754.0, "monoisotopic_mass": 110754.0 }, "refseq": { "ac": "XP_040505313", "name": "ral guanine nucleotide dissociation stimulator isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505313" }, "gene_names": [ { "name": "RGL4", "type": "recommended", "evidence": [ { "id": "A0A8V1AIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ] }, { "name": "RGL4", "type": "synonym", "evidence": [ { "id": "XP_040505313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505313" } ] } ], "protein_names": [ { "name": "Ral guanine nucleotide dissociation stimulator like 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5/entry#names_and_taxonomy" } ] }, { "name": "ral guanine nucleotide dissociation stimulator isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040505313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505313" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17209", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17209", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427758", "url": "https://www.ncbi.nlm.nih.gov/gene/427758", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAX5", "url": "https://www.orthodb.org/?gene=A0A8V1AAX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG91", "url": "https://www.orthodb.org/?gene=A0A8V1AG91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIB5", "url": "https://www.orthodb.org/?gene=A0A8V1AIB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM86", "url": "https://www.orthodb.org/?gene=A0A8V1AM86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-171007", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-171007", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5673001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040505313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG91", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM86", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPWGLSSWDGKQPGCSTGLILSGGFEAVRSEPQSWMLGAVRTLGDAETLLQGRRPTLHGFSHCRPPPSPFALLRAAPSRTPPQLPAEAQPPPPAPSPRGPSRAGPGQPPGRAEAAGEEIQAPLSEPGPSVPSGCSAAAPSGSRPPIPVAVAVRVPGYPGIPVPPGRPGDAVAVPMVSRRHHAAPPAPDMFEGCRRARSLWGGVRLEVAGESSPVVLHSFTQLDPDLPPLESSTQEIGEELEDGVIYSISLRKVQLHHTANKGQRWLGFENESALNLYETCKVRTIKAGTLEKLVEYLVSAFKGNDSTYVTIFLCTYRAFATTKQVLDLLLNRYGKLHVQTNGDHARHVVDERMELKNTISSILGAWLDQYSEDFRKPPDFTCLKQLISYVRHNIPGSDLERRARILLAQFQQQEQSETEAEAVDHSGCTFQLVEENGVGDGKSDFLSFSPEMVAEQFTLMDAELFKKVVPYHCLGCIWSQRDKKGKEHLAPTIRATVSQFNSVANCVIATCLGDRTLKPQQRAKVVERWIEVARECRILKNFSSLRAILSALQCNAVHRLKKTWDEVLRESFRTFHELSEIFSDENNHSLSRELLIKEGTSKFATLEINPKRAQKRQQQQREMGVMQGTIPYLGTFLTDLVMLDTAMKDFLDGGLINFEKRRKEFEVIAQIKLLQSACNNYSFTQEDHFVDWFHSLERLSEAESYGLSCEIEPLSESASNTLKAKKNTGIIKRWSDRQPASTEPCASGSSHSKSFDQLKCGQYLCSGDATDSVSVTSAGSSSSDVEEINISFIPESPDCQEKKHSYAPSVADGEAKPTVSSASPLLPALQFWESTSLSSLDTSGIGSGSSSASSSSVSSTPVTASRTHKRSVSGISSYSSLSLPLYNQQVDDCCIIRVSLAVDNGNMYKSILVTSQDKTPVVIRKAMAKHNLDGDRPEDYELVQIISEERELKIPDNANVFYAMNSAANYDFVLKKRGFSKGVKIKHGSSSTLPRMKQKGLKIAKGIF", "length": 1009, "header": "tr|A0A8V1AIB5-1|A0A8V1AIB5_CHICK Isoform 1 of Ral guanine nucleotide dissociation stimulator like 4 OS=Gallus gallus OX=9031 GN=RGL4 PE=4 SV=1 CANONICAL=A0A8V1AIB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5/entry#A0A8V1AAX5-1", "sequence": { "sequence": "MSSTQEIGEELEDGVIYSISLRKVQLHHTANKGQRWLGFENESALNLYETCKVRTIKAGTLEKLVEYLVSAFKGNDSTYVTIFLCTYRAFATTKQVLDLLLNRYGKLHVQTNGDHARHVVDERMELKNTISSILGAWLDQYSEDFRKPPDFTCLKQLISYVRHNIPGSDLERRARILLAQFQQQEQSETEAEAVDHSGCTFQLVEENGVGDGKSDFLSFSPEMVAEQFTLMDAELFKKVVPYHCLGCIWSQRDKKGKEHLAPTIRATVSQFNSVANCVIATCLGDRTLKPQQRAKVVERWIEVARECRILKNFSSLRAILSALQCNAVHRLKKTWDEVLRESFRTFHELSEIFSDENNHSLSRELLIKEGTSKFATLEINPKRAQKRQQQQREMGVMQGTIPYLGTFLTDLVMLDTAMKDFLDGGLINFEKRRKEFEVIAQIKLLQSACNNYSFTQEDHFVDWFHSLERLSEAESYGLSCEIEPLSESASNTLKAKKNTGIIKRWSDRQPASTEPCASGSSHSKSFDQLKCGQYLCSGDATDSVSVTSAGSSSSDVEEINISFIPESPDCQEKKFWESTSLSSLDTSGIGSGSSSASSSSVSSTPVTASRTHKRSVSGISSYSSLSLPLYNQQVDDCCIIRVSLAVDNGNMYKSILVTSQDKTPVVIRKAMAKHNLDGDRPEDYELVQIISEERELKIPDNANVFYAMNSAANYDFVLKKRGFSKGVKIKHGSSSTLPRMKQKGLKIAKGIF", "length": 752, "header": "tr|A0A8V1AAX5-1|A0A8V1AAX5_CHICK Computationally mapped isoform of Ral guanine nucleotide dissociation stimulator like 4 OS=Gallus gallus OX=9031 GN=RGL4 PE=4 SV=1 CANONICAL=A0A8V1AIB5-1" }, "locus": { "chromosome": "17", "start_pos": 7420992, "end_pos": 7397022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070438.1", "url": "https://www.ensembl.org/id/ENSGALT00010070438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043129.1", "url": "https://www.ensembl.org/id/ENSGALP00010043129.1" } ] } }, { "isoform_ac": "A0A8V1AG91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5/entry#A0A8V1AG91-1", "sequence": { "sequence": "MMMIDSQSSTQEIGEELEDGVIYSISLRKVQLHHTANKGQRWLGFENESALNLYETCKVRTIKAGTLEKLVEYLVSAFKGNDSTYVTIFLCTYRAFATTKQVLDLLLNRYGKLHVQTNGDHARHVVDERMELKNTISSILGAWLDQYSEDFRKPPDFTCLKQLISYVRHNIPGSDLERRARILLAQFQQQEQSETEAEAVDHSGCTFQLVEENGVGDGKSDFLSFSPEMVAEQFTLMDAELFKKVVPYHCLGCIWSQRDKKGKEHLAPTIRATVSQFNSVANCVIATCLGDRTLKPQQRAKVVERWIEVARECRILKNFSSLRAILSALQCNAVHRLKKTWDEVLRESFRTFHELSEIFSDENNHSLSRELLIKEGTSKFATLEINPKRAQKRQQQQREMGVMQGTIPYLGTFLTDLVMLDTAMKDFLDGGLINFEKRRKEFEVIAQIKLLQSACNNYSFTQEDHFVDWFHSLERLSEAESYGLSCEIEPLSESASNTLKAKKNTGIIKRWSDRQPASTEPCASGSSHSKSFDQLKCGQYLCSGDATDSVSVTSAGSSSSDVEEINISFIPESPDCQEKKHSYAPSVADGEAKPTVSSASPLLPALQFWESTSLSSLDTSGIGSGSSSASSSSVSSTPVTASRTHKRSVSGISSYSSLSLPLYNQQVDDCCIIRVSLAVDNGNMYKSILVTSQDKTPVVIRKAMAKHNLDGDRPEDYELVQIISEERELKIPDNANVFYAMNSAANYDFVLKKRGFSKGVKIKHGSSSTLPRMKQKGLKIAKGIF", "length": 785, "header": "tr|A0A8V1AG91-1|A0A8V1AIB5_CHICK Computationally mapped isoform of Ral guanine nucleotide dissociation stimulator like 4 OS=Gallus gallus OX=9031 GN=RGL4 PE=4 SV=1 CANONICAL=A0A8V1AIB5-1" }, "locus": { "chromosome": "17", "start_pos": 7434594, "end_pos": 7397022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070440.1", "url": "https://www.ensembl.org/id/ENSGALT00010070440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043131.1", "url": "https://www.ensembl.org/id/ENSGALP00010043131.1" } ] } }, { "isoform_ac": "A0A8V1AIB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5/entry#A0A8V1AIB5-1", "sequence": { "sequence": "MAPWGLSSWDGKQPGCSTGLILSGGFEAVRSEPQSWMLGAVRTLGDAETLLQGRRPTLHGFSHCRPPPSPFALLRAAPSRTPPQLPAEAQPPPPAPSPRGPSRAGPGQPPGRAEAAGEEIQAPLSEPGPSVPSGCSAAAPSGSRPPIPVAVAVRVPGYPGIPVPPGRPGDAVAVPMVSRRHHAAPPAPDMFEGCRRARSLWGGVRLEVAGESSPVVLHSFTQLDPDLPPLESSTQEIGEELEDGVIYSISLRKVQLHHTANKGQRWLGFENESALNLYETCKVRTIKAGTLEKLVEYLVSAFKGNDSTYVTIFLCTYRAFATTKQVLDLLLNRYGKLHVQTNGDHARHVVDERMELKNTISSILGAWLDQYSEDFRKPPDFTCLKQLISYVRHNIPGSDLERRARILLAQFQQQEQSETEAEAVDHSGCTFQLVEENGVGDGKSDFLSFSPEMVAEQFTLMDAELFKKVVPYHCLGCIWSQRDKKGKEHLAPTIRATVSQFNSVANCVIATCLGDRTLKPQQRAKVVERWIEVARECRILKNFSSLRAILSALQCNAVHRLKKTWDEVLRESFRTFHELSEIFSDENNHSLSRELLIKEGTSKFATLEINPKRAQKRQQQQREMGVMQGTIPYLGTFLTDLVMLDTAMKDFLDGGLINFEKRRKEFEVIAQIKLLQSACNNYSFTQEDHFVDWFHSLERLSEAESYGLSCEIEPLSESASNTLKAKKNTGIIKRWSDRQPASTEPCASGSSHSKSFDQLKCGQYLCSGDATDSVSVTSAGSSSSDVEEINISFIPESPDCQEKKHSYAPSVADGEAKPTVSSASPLLPALQFWESTSLSSLDTSGIGSGSSSASSSSVSSTPVTASRTHKRSVSGISSYSSLSLPLYNQQVDDCCIIRVSLAVDNGNMYKSILVTSQDKTPVVIRKAMAKHNLDGDRPEDYELVQIISEERELKIPDNANVFYAMNSAANYDFVLKKRGFSKGVKIKHGSSSTLPRMKQKGLKIAKGIF", "length": 1009, "header": "tr|A0A8V1AIB5-1|A0A8V1AIB5_CHICK Isoform 1 of Ral guanine nucleotide dissociation stimulator like 4 OS=Gallus gallus OX=9031 GN=RGL4 PE=4 SV=1 CANONICAL=A0A8V1AIB5-1" }, "locus": { "chromosome": "17", "start_pos": 7415377, "end_pos": 7397022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070437.1", "url": "https://www.ensembl.org/id/ENSGALT00010070437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043128.1", "url": "https://www.ensembl.org/id/ENSGALP00010043128.1" } ] } }, { "isoform_ac": "A0A8V1AM86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5/entry#A0A8V1AM86-1", "sequence": { "sequence": "MSSPSVPGKMEAKPLFNVQKALVQPVQMCMLDIPLSVQDDDSSTQEIGEELEDGVIYSISLRKVQLHHTANKGQRWLGFENESALNLYETCKVRTIKAGTLEKLVEYLVSAFKGNDSTYVTIFLCTYRAFATTKQVLDLLLNRYGKLHVQTNGDHARHVVDERMELKNTISSILGAWLDQYSEDFRKPPDFTCLKQLISYVRHNIPGSDLERRARILLAQFQQQEQSETEAEAVDHSGCTFQLVEENGVGDGKSDFLSFSPEMVAEQFTLMDAELFKKVVPYHCLGCIWSQRDKKGKEHLAPTIRATVSQFNSVANCVIATCLGDRTLKPQQRAKVVERWIEVARECRILKNFSSLRAILSALQCNAVHRLKKTWDEVLRESFRTFHELSEIFSDENNHSLSRELLIKEGTSKFATLEINPKRAQKRQQQQREMGVMQGTIPYLGTFLTDLVMLDTAMKDFLDGGLINFEKRRKEFEVIAQIKLLQSACNNYSFTQEDHFVDWFHSLERLSEAESYGLSCEIEPLSESASNTLKAKKNTGIIKRWSDRQPASTEPCASGSSHSKSFDQLKCGQYLCSGDATDSVSVTSAGSSSSDVEEINISFIPESPDCQEKKHSYAPSVADGEAKPTVSSASPLLPALQFWESTSLSSLDTSGIGSGSSSASSSSVSSTPVTASRTHKRSVSGISSYSSLSLPLYNQQVDDCCIIRVSLAVDNGNMYKSILVTSQDKTPVVIRKAMAKHNLDGDRPEDYELVQIISEERELKIPDNANVFYAMNSAANYDFVLKKRGFSKGVKIKHGSSSTLPRMKQKGLKIAKGIF", "length": 819, "header": "tr|A0A8V1AM86-1|A0A8V1AM86_CHICK Computationally mapped isoform of Ral guanine nucleotide dissociation stimulator like 4 OS=Gallus gallus OX=9031 GN=RGL4 PE=4 SV=1 CANONICAL=A0A8V1AIB5-1" }, "locus": { "chromosome": "17", "start_pos": 7425537, "end_pos": 7397022, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070439.1", "url": "https://www.ensembl.org/id/ENSGALT00010070439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043130.1", "url": "https://www.ensembl.org/id/ENSGALP00010043130.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-171007", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-171007", "resource": "Reactome", "description": "p38MAPK events" }, { "id": "R-GGA-5673001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673001", "resource": "Reactome", "description": "RAF/MAP kinase cascade" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "pmid": "" }, { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" }, { "id": "PS50212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-terminal Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 282, "end_pos": 412, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 450, "end_pos": 715, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIB5" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 893, "end_pos": 980, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 790, "end_pos": 792 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIJ8-1", "uniprot_ac": "A0A8V1AIJ8", "uniprot_id": "A0A8V1AIJ8_CHICK", "mass": { "chemical_mass": 136162.0, "monoisotopic_mass": 136162.0 }, "refseq": { "ac": "XP_040509623", "name": "RNA exonuclease 1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509623" }, "gene_names": [ { "name": "REXO1", "type": "recommended", "evidence": [ { "id": "A0A8V1AIJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8" } ] }, { "name": "REXO1", "type": "synonym", "evidence": [ { "id": "XP_040509623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509623" } ] } ], "protein_names": [ { "name": "RNA exonuclease 1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040509623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509623" } ] }, { "name": "RNA exonuclease 1 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1AIJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509623" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "REXO1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8", "locus": { "chromosome": "28", "start_pos": 2695648, "end_pos": 2664340, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028429", "url": "https://www.ensembl.org/id/ENSGALG00010028429" } ] } } ], "crossref": [ { "id": "A0A8V1AIJ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06145", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06145", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428327", "url": "https://www.ncbi.nlm.nih.gov/gene/428327", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428327", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428327", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIRMQYY", "url": "https://omabrowser.org/oma/group/NIRMQYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A8L8", "url": "https://www.orthodb.org/?gene=A0A8V1A8L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGA4", "url": "https://www.orthodb.org/?gene=A0A8V1AGA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIJ8", "url": "https://www.orthodb.org/?gene=A0A8V1AIJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12801", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12801", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12801:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12801:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00929", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00929", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15870", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15870", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040509623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A8L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVKEGGTWGGKPCPNDRHSPEVLCQHTVSVVSLKPVPECQADSESLEYSMNKYLQYLLTTGSSERGYDPYNPELPKPSLEAEDGALADLTDMTPGILELELVNKAIEAVKNEVEREQKKYEELLETTKELRASDSSLISETPVSAAVTQSDLFTSLEYNPGSYNFSNNSDYNPTPFAAGQSSKYTLDSLRSKGNSLEYVPKAVAQSKKYSSTVTNNKYVIDDSKPSTDLEYDPLSNYSARLLSKATTKELKGSKRGRAPSYEDPYSPSRKKLCEVPDEYEVCARFSSSEDEADAEYKSTSVSSPSKAGSESESEDGLSNKERSAASGDFSSQGSKETAAKYGMEDLPSSQKIPPKTALEKNAKAAKSYSGKNDQETENKNKESKDKTKRKKSDVSKTPGLSEVSKKEKSKNAEKDKVGKKEEKVKTKNEEKNCKDKSVKVKTDGNLKKADKHKSERVDELKKEKSKGSSISSGKSKSEDVTKGSSTEKLGGSKKESKLKTGDVKNGKETSSSKNKDKGTKTSTVEQKKEKVNPAGKGDPKKGQKQQSLSHVDLFGDESGDEDDKGKPMPSTLPDVSSDSDGDSSGSDSQSENGKTKRAKRSKLSKSSSSSSMSDDIDYSILEKDLDFETDPMEECLRIFNESTDVKTEDKGRLGKQPSKEEVNKEKTEENLTTLFPGQKRRISHLVKQGNAEVPNRPVVRPYRPPTAQEVCYQRIQLAQQQAAQLAVAVQKASLSLPGEKRRIAHVPNVALTAAVKQSLVSGKKTAAGKSVTPANDSEAPTLSLKACTLAGMASKTTSTTVQKRIAHVPSLQSASLQRPVIPTEFGAKVPTNIRQRYLNLFIDECLKFCSSSQEAFDKALAEEKVAYERSTSRNIYLNVAVNTLKKLRSLVPNSPSSTNKTSNKKVVSHEAVLGGKLAAKTSFTLNRSGSLKAEDLTGAALYRRLKEYLMTEEQLKENGYPMPHPEKPGRAVLFTAEEKKSTDSSCRICCRCGTEYMVSASGSCIRKEECVHHWGRLRKQRVPGGWETHYSCCSGAVGSAGCQVAKQHVHDGRKESLDGFVKTFEKLPTTDGYPGIFALDCEMCYTKQGLELTRVTVINSDLKVVYDTFVKPDTKVVDYNTRFSGVTEEDLENTSITLRDVQAVLLNMFSADTILIGHSLESDLFALKLIHGTVVDTAIVFPHRLGLPYKRALRTLMADYLKRIIQDNVEGHDSSEDARACMELMIWKIKEDSKVKR", "length": 1238, "header": "tr|A0A8V1AIJ8-1|A0A8V1AIJ8_CHICK Isoform 1 of RNA exonuclease 1 homolog OS=Gallus gallus OX=9031 GN=REXO1 PE=3 SV=1 CANONICAL=A0A8V1AIJ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8/entry#A0A8V1A8L8-1", "sequence": { "sequence": "MLRSTGYFRGIDCPFLTAAGGPPCRRPYCHFRHPPVAAARCGAPGAGGALGLGAERGYDPYNPELPKPSLEAEDGALADLTDMTPGILELELVNKAIEAVKNEVEREQKKYEELLETTKELRASDSSLISETPVSAAVTQSDLFTSLEYNPGSYNFSNNSDYNPTPFAAGQSSKYTLDSLRSKGNSLEYVPKAVAQSKKYSSTVTNNKYVIDDSKPSTDLEYDPLSNYSARLLSKATTKELKGSKRGRAPSYEDPYSPSRKKLCEVPDEYEVCARFSSSEDEADAEYKSTSVSSPSKAGSESESEDGLSNKERSAASGDFSSQGSKETAAKYGMEDLPSSQKIPPKTALEKNAKAAKSYSGKNDQETENKNKESKDKTKRKKSDVSKTPGLSEVSKKEKSKNAEKDKVGKKEEKVKTKNEEKNCKDKSVKVKTDGNLKKADKHKSERVDELKKEKSKGSSISSGKSKSEDVTKGSSTEKLGGSKKESKLKTGDVKNGKETSSSKNKDKGTKTSTVEQKKEKVNPAGKGDPKKGQKQQSLSHVDLFGDESGDEDDKGKPMPSTLPDVSSDSDGDSSGSDSQSENGKTKRAKRSKLSKSSSSSSMSDDIDYSILEKDLDFETDPMEECLRIFNESTDVKTEDKGRLGKQPSKEEVNKEKTEENLTTLFPGQKRRISHLVKQGNAEVPNRPVVRPYRPPTAQEVCYQRIQLAQQQAAQLAVAVQKASLSLPGEKRRIAHVPNVALTAAVKQSLVSGKKTAAGKSVTPANDSEAPTLSLKACTLAGMASKTTSTTVQKRIAHVPSLQSASLQRPVIPTEFGAKVPTNIRQRYLNLFIDECLKFCSSSQEAFDKALAEEKVAYERSTSRNIYLNVAVNTLKKLRSLVPNSPSSTNKTSNKKVVSHEAVLGGKLAAKTSFTLNRSGSLKAEDLTGAALYRRLKEYLMTEEQLKENGYPMPHPEKPGRAVLFTAEEKKSTDSSCRICCRCGTEYMVSASGSCIRKEECVHHWGRLRKQRVPGGWETHYSCCSGAVGSAGCQVAKQHVHDGRKESLDGFVKTFEKLPTTDGYPGIFALDCEMCYTKQGLELTRVTVINSDLKVVYDTFVKPDTKVVDYNTRFSGVTEEDLENTSITLRDVQAVLLNMFSADTILIGHSLESDLFALKLIHGTVVDTAIVFPHRLGLPYKRALRTLMADYLKRIIQDNVEGHDSSEDARACMELMIWKIKEDSKVKR", "length": 1228, "header": "tr|A0A8V1A8L8-1|A0A8V1A8L8_CHICK Computationally mapped isoform of RNA exonuclease 1 homolog OS=Gallus gallus OX=9031 GN=REXO1 PE=3 SV=1 CANONICAL=A0A8V1AIJ8-1" }, "locus": { "chromosome": "28", "start_pos": 2695576, "end_pos": 2664409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068858.1", "url": "https://www.ensembl.org/id/ENSGALT00010068858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042300.1", "url": "https://www.ensembl.org/id/ENSGALP00010042300.1" } ] } }, { "isoform_ac": "A0A8V1AGA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8/entry#A0A8V1AGA4-1", "sequence": { "sequence": "MLRSTGYFRGIDCPFLTAAGGPPCRRPYCHFRHPPVAAARCGAPGAGGALGLGAERGYDPYNPELPKPSLEAEDGALADLTDMTPGILELELVNKAIEAVKNEVEREQKKYEELLETTKELRASDSSLISETPVSAAVTQSDLFTSLEYNPGSYNFSNNSDYNPTPFAAGQSSKYTLDSLRSKGNSLEYVPKAVAQSKKYSSTVTNNKYVIDDSKPSTDLEYDPLSNYSARLLSKATTKELKGSKRGRAPSYEDPYSPSRKKLCEVPDEYEVCARFSSSEDEADAEYKSTSVSSPSKAGSESESEDGLSNKERSAASGDFSSQGSKETAAKYGMEDLPSSQKIPPKTALEKNAKAAKSYSGKNDQETENKNKESKDKTKRKKSDVSKTPGLSEVSKKEKSKNAEKDKVGKKEEKVKTKNEEKNCKDKSVKVKTDGNLKKADKHKSERVDELKKEKSKGSSISSGKSKSEDVTKGSSTEKLGGSKKESKLKTGDVKNGKETSSSKNKDKGTKTSTVEQKKEKVNPAGKGDPKKGQKQQSLSHVDLFGDESGDEDDKGKPMPSTLPDVSSDSDGDSSGSDSQSENGKTKRAKRSKLSKSSSSSSMSDDIDYSILEKDLDFETDPMEECLRIFNESTDVKTEDKGRLGKQPSKEEVNKEKTEENLTTLFPGQKRRISHLVKQGNAEVPNRPVVRPYRPPTAQEVCYQRIQLAQQQAAQLAVAVQKASLSLPGEKRRIAHVPNVALTAAVKQSLVSGKKTAAGKSVTPANDSEAPTLSLKACTLAGMASKTTSTTVQKRIAHVPSLQSASLQRPVIPTEFGAKVPTNIRQRYLNLFIDECLKFCSSSQEAFDKALAEEKVAYERSTSRNIYLNVAVNTLKKLRSLVPNSPSSTNKTSNKKVVSHEAVLGGKLAAKTSFTLNRSGSLKAEDLTGAALYRRLKEYLMTEEQLKENGYPMPHPEKPGRAVLFTAEEKKSTDSSCRICCRCGTEYMVSASGSCIRKEECVHHWGRLRKQRVPGGWETHYSCCSGAVGSAGCQVAKQHVHDGRKESLDGFVKTFEKLPTTDGYPGIFALDCEMCYTKQGLELTRVTVINSDLKVVYDTFVKPDTKVVDYNTRFSGVTEEDLENTSITLRDVQAVLLNMFSADTILIGHSLESDLFALKLIHGTVVDTAIVFPHRLGLPYKRALRTLMADYLKRIIQDNAVNRPVCEGCAAVLV", "length": 1214, "header": "tr|A0A8V1AGA4-1|A0A8V1AIJ8_CHICK Computationally mapped isoform of RNA exonuclease 1 homolog OS=Gallus gallus OX=9031 GN=REXO1 PE=3 SV=1 CANONICAL=A0A8V1AIJ8-1" }, "locus": { "chromosome": "28", "start_pos": 2695104, "end_pos": 2664409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068857.1", "url": "https://www.ensembl.org/id/ENSGALT00010068857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042299.1", "url": "https://www.ensembl.org/id/ENSGALP00010042299.1" } ] } }, { "isoform_ac": "A0A8V1AIJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8/entry#A0A8V1AIJ8-1", "sequence": { "sequence": "MRVKEGGTWGGKPCPNDRHSPEVLCQHTVSVVSLKPVPECQADSESLEYSMNKYLQYLLTTGSSERGYDPYNPELPKPSLEAEDGALADLTDMTPGILELELVNKAIEAVKNEVEREQKKYEELLETTKELRASDSSLISETPVSAAVTQSDLFTSLEYNPGSYNFSNNSDYNPTPFAAGQSSKYTLDSLRSKGNSLEYVPKAVAQSKKYSSTVTNNKYVIDDSKPSTDLEYDPLSNYSARLLSKATTKELKGSKRGRAPSYEDPYSPSRKKLCEVPDEYEVCARFSSSEDEADAEYKSTSVSSPSKAGSESESEDGLSNKERSAASGDFSSQGSKETAAKYGMEDLPSSQKIPPKTALEKNAKAAKSYSGKNDQETENKNKESKDKTKRKKSDVSKTPGLSEVSKKEKSKNAEKDKVGKKEEKVKTKNEEKNCKDKSVKVKTDGNLKKADKHKSERVDELKKEKSKGSSISSGKSKSEDVTKGSSTEKLGGSKKESKLKTGDVKNGKETSSSKNKDKGTKTSTVEQKKEKVNPAGKGDPKKGQKQQSLSHVDLFGDESGDEDDKGKPMPSTLPDVSSDSDGDSSGSDSQSENGKTKRAKRSKLSKSSSSSSMSDDIDYSILEKDLDFETDPMEECLRIFNESTDVKTEDKGRLGKQPSKEEVNKEKTEENLTTLFPGQKRRISHLVKQGNAEVPNRPVVRPYRPPTAQEVCYQRIQLAQQQAAQLAVAVQKASLSLPGEKRRIAHVPNVALTAAVKQSLVSGKKTAAGKSVTPANDSEAPTLSLKACTLAGMASKTTSTTVQKRIAHVPSLQSASLQRPVIPTEFGAKVPTNIRQRYLNLFIDECLKFCSSSQEAFDKALAEEKVAYERSTSRNIYLNVAVNTLKKLRSLVPNSPSSTNKTSNKKVVSHEAVLGGKLAAKTSFTLNRSGSLKAEDLTGAALYRRLKEYLMTEEQLKENGYPMPHPEKPGRAVLFTAEEKKSTDSSCRICCRCGTEYMVSASGSCIRKEECVHHWGRLRKQRVPGGWETHYSCCSGAVGSAGCQVAKQHVHDGRKESLDGFVKTFEKLPTTDGYPGIFALDCEMCYTKQGLELTRVTVINSDLKVVYDTFVKPDTKVVDYNTRFSGVTEEDLENTSITLRDVQAVLLNMFSADTILIGHSLESDLFALKLIHGTVVDTAIVFPHRLGLPYKRALRTLMADYLKRIIQDNVEGHDSSEDARACMELMIWKIKEDSKVKR", "length": 1238, "header": "tr|A0A8V1AIJ8-1|A0A8V1AIJ8_CHICK Isoform 1 of RNA exonuclease 1 homolog OS=Gallus gallus OX=9031 GN=REXO1 PE=3 SV=1 CANONICAL=A0A8V1AIJ8-1" }, "locus": { "chromosome": "28", "start_pos": 2695576, "end_pos": 2669097, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068856.1", "url": "https://www.ensembl.org/id/ENSGALT00010068856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042298.1", "url": "https://www.ensembl.org/id/ENSGALP00010042298.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 773, "start_aa": "Thr", "end_pos": 773, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr773", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428327", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428327", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G5B7-1", "protein_name": "RNA exonuclease 1 homolog isoform X1", "gene_name": "Rexo1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRSTGFFRSIDCPYWAGAPGGPCRRPYCHFRHRGARGPGTPGGSSAASPAAGLGYDPYNPELPQPPAQRENDGMLELELVNQAIEAVRGEVELERRRYQELLGTARGHGAGASTLAPCSPPASLDDDDTFSLTLTYTPGGLLSPDSSYQPTPLAAPDDPGHKYSLVPSERGQGRAGGGTSALEYVPKAVGQPRHSGRPVSGGKYVVDSSKPSTDLEYDPLSNYSARHLGRASVRDERATKRPRGSRGAEPYTPAIKKPCDPFGGCEARFSDSEDDVAGPPEAESSSPMVPGKPASKDGPKPKEGSLRDTKEMAVQYDVEDLGQPPRAADTVALAKLGSPARASQVAGVPKDGKAKKKKSGIPTSLSHKDKSRKRDKKKDKDPGRPREKEKAYTDRKKSQTGSPRGKAQGPEGTKKKPSNITMVASSGKERPGCPSSGGPQPQDSGPSPHTLLAWKGGSARKTPPGKLVDRKARSLDGGAPQGAPKLKKRALSHAELFGDESEEEEDSGLGPRAPRVWPPTLPTLSSDSDSDSDSSLGLSETQVPKRLKAAPPTSPAPPSPLSSSSSSSSGTSQCAEGDVDYSALEKEVDFDADPMEECLRIFNESTSVKTEDKGRLARQPPKEKAVEKTHAGLTTLFPGQKRRVSHLCKSGKEAEAPKRAPVAPPARPPTAQEVCYRRAQQAQRDSTSWLQAATRPTDKLSSVHISAPGEKRRIAHVPNPRLATTPTGAKRALPASSSQVSHGPEPGSQPLKTRTLSGMASKTTTTVIPKRIAHSPSLQSLKKPIIPKEFGGKVPTVVRQRYLNLFIEECLKFCSSNQEAIEKALNEEKVAYERSPSKNIYLNVAVNTLKKLRGLVPNTVPSLSKASGRRVVSHEVVLGGKLAAKTSFSLSRPSSPRVEELRGNALYSRLREYLLTQEQLKENGYPFPHPERPGGAVIFTAEEKKPKDSSCRICCRCGTEYLVSSSGRCVRNEECYYHWGRLRRNRVAGGWETQYMCCSAAVGSVGCQVAKPFQSGAHWAHLPPQAPGPDLARAGKSPCVACASPAADLPVPQQHVQDGRKENLEGFVRTFQKELPEDSHAGVFALDCEMSYTTYGLELTRVTVVDTDMQVVYDTFVKPDNEVVDYNTRFSGVTEADLVDTSVTLRDVQAVLLSMFSADTILIGHSLESDLLALKVIHSTVVDTSVLFPHRLGLPYKRSLRNLMADYLRQIIQDNVDGHSSSEDASACMHLVIWKIREDAKTKR", "length": 1245 }, "evidence": [ { "id": "A0A8V1AIJ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIJ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B0S6F3-1", "protein_name": "RNA exonuclease 1 homolog", "gene_name": "rexo1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"length": 1207 }, "evidence": [ { "id": "A0A8V1AIJ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIJ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZCX6-1", "protein_name": "RNA exonuclease 1 homolog", "gene_name": "Rexo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1197 }, "evidence": [ { "id": "A0A8V1AIJ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2PDP6-1", "protein_name": "Exonuclease domain-containing protein", "gene_name": "Dmel\\CG12877", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"length": 991 }, "evidence": [ { "id": "A0A8V1AIJ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIJ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7TT28-1", "protein_name": "RNA exonuclease 1 homolog", "gene_name": "Rexo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1213 }, "evidence": [ { "id": "A0A8V1AIJ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N1G1-1", "protein_name": "RNA exonuclease 1 homolog", "gene_name": "REXO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V1AIJ8" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA 3'-end processing", "id": "GO:0031125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1134, "end_pos": 1136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI75-1", "uniprot_ac": "A0A8V1AI75", "uniprot_id": "A0A8V1AI75_CHICK", "mass": { "chemical_mass": 71200.0, "monoisotopic_mass": 71200.0 }, "refseq": {}, "gene_names": [ { "name": "PBXIP1", "type": "recommended", "evidence": [ { "id": "A0A8V1AI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ] } ], "protein_names": [ { "name": "PBX homeobox interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PBXIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75", "locus": { "chromosome": "25", "start_pos": 2013306, "end_pos": 2017184, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027908", "url": "https://www.ensembl.org/id/ENSGALG00010027908" } ] } } ], "crossref": [ { "id": "A0A8V1AI75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AI75", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857958", "url": "https://www.ncbi.nlm.nih.gov/gene/100857958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GCARQEG", "url": "https://omabrowser.org/oma/group/GCARQEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A657", "url": "https://www.orthodb.org/?gene=A0A8V1A657", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGC8", "url": "https://www.orthodb.org/?gene=A0A8V1AGC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGD2", "url": "https://www.orthodb.org/?gene=A0A8V1AGD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI75", "url": "https://www.orthodb.org/?gene=A0A8V1AI75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28638:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28638:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A657", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A657", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A657-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A657-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQKSDSRDSDNSWVLTGTEGLPVDTVGPERDSASHEDEEEEGEEEDTPDAGTADGSEDGAASLGEKQHPEVGGAEGRSDPGAGTELPTSDPTELSATDSWEQEKHNTEPGLRAEGRTAEPLLEEGSCTSSDDDVEELRRRQVHHQPPAGTPPPAPIPRRVMQDEGNEEGLSANKLLLGALALVAVALLIVSGGFYDVADGPADVMSHDATDMEQEAVPDNGSVRSGAAMGLPHPQHPQSRIPPPPPPQDSPQKPPLDSGDVHSMQSMSVLLDRLAKENQDIRLMQAELQAHKEELQALLQQSEGAAAAAGAQQQSLAKENAELRAALQREAEALRAARAELQRLQARGGPGDHQPHKEQPHDPGAAVHGEGARDEARNRGLLASVRHELAAALQRARGAGGLEGLMEELRVLEERLSRELRGGEGAEAFPGHWKKGFKAEKKERGWHKRDGHRERGKAHRHGWEPHGKEPHGKEPHGKEPHSKERHGKEQHSKEPRPHREHREGKAGGKWSHGPRDHHVPPLSHSRPPQGCSGVTDCAHKEGREALGAALEPVQKAQFLQLLEGFMGRLGWGGHFGGVAERLDGAFGANGVFAHDRRRFVDFVEEVEEMLEDVARREHGDEEAADGFEEFVLQHYAGSVGKERGRKTWRQHGGGR", "length": 656, "header": "tr|A0A8V1AI75-1|A0A8V1AI75_CHICK Isoform 1 of PBX homeobox interacting protein 1 OS=Gallus gallus OX=9031 GN=PBXIP1 PE=4 SV=1 CANONICAL=A0A8V1AI75-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A657-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75/entry#A0A8V1A657-1", "sequence": { "sequence": "MAQKSDSRDSDNSWVLTGTEGLPVDTVGPERDSASHEDEEEEGEEEDTPDAGTADGSEDGAASLGEKQHPEVGGAEGRSDPGAGTELPTSDPTELSATDSWEQEKHNTEPGLRAEGRTAEPLLEEGSCTSSDDDVEELRRRQVHHQPPAGTPPPAPIPRRVMQDEGNEEGLSANKLLLGALALVAVALLIVSGGFYDVADGPADVMSHDATDMEQEAVPDNGSDSPQKPPLDSGDVHSMQSMSVLLDRLAKENQDIRLMQAELQAHKEELQALLQQSEGAAAAAGAQQQSLAKENAEALRAARAELQRLQARGGPGDHQPHKEQPHDPGAAVHGEGARDEARNRGLLASVRHELAAALQRARGAGGLEGLMEELRVLEERLSRELRGGEGAEAFPGHWKKGFKAEKKERGWHKRDGHRERGKAHRHGWEPHGKEPHGKEPHGKEPHSKERHGKEQHSKEPRPHREHREGKAGGKWSHGPRDHHVPPLSHSRPPQGCSGVTDCAHKEGREALGAALEPVQKAQFLQLLEGFMGRLGWGGHFGGVAERLDGAFGANGVFAHDRRRFVDFVEEVEEMLEDVARREHGDEEAADGFEEFVLQHYAGSVGKERGRKTWRQHGGGR", "length": 620, "header": "tr|A0A8V1A657-1|A0A8V1A657_CHICK Computationally mapped isoform of PBX homeobox interacting protein 1 OS=Gallus gallus OX=9031 GN=PBXIP1 PE=4 SV=1 CANONICAL=A0A8V1AI75-1" }, "locus": { "chromosome": "25", "start_pos": 2016117, "end_pos": 2013480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067655.1", "url": "https://www.ensembl.org/id/ENSGALT00010067655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041398.1", "url": "https://www.ensembl.org/id/ENSGALP00010041398.1" } ] } }, { "isoform_ac": "A0A8V1AGC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75/entry#A0A8V1AGC8-1", "sequence": { "sequence": "MAQKSDSRDSDNSWVLTGTEGLPVDTVGPERDSASHEDEEEEGEEEDTPDAGTADGSEDGAASLGEKQHPEVGGAEGRSDPGAGTELPTSDPTELSATDSWEQEKHNTEPGLRAEGRTAEPLLEEGSCTSSDDDVEELRRRQVHHQPPAGTPPPAPIPRRVMQDEGNEEGLSANKLLLGALALVAVALLIVSGPADVMSHDATDMEQEAVPDNGSVRSGAAMGLPHPQHPQSRIPPPPPPQDSPQKPPLDSGDVHSMQSMSVLLDRLAKENQDIRLMQAELQAHKEELQALLQQSEGAAAAAGAQQQSLAKENAELRAALQREAEALRAARAELQRLQARGGPGDHQPHKEQPHDPGAAVHGEGARDEARNRGLLASVRHELAAALQRARGAGGLEGLMEELRVLEERLSRELRGGEGAEAFPGHWKKGFKAEKKERGWHKRDGHRERGKAHRHGWEPHGKEPHGKEPHGKEPHSKERHGKEQHSKEPRPHREHREGKAGGKWSHGPRDHHVPPLSHSRPPQGCSGVTDCAHKEGREALGAALEPVQKAQFLQLLEGFMGRLGWGGHFGGVAERLDGAFGANGVFAHDRRRFVDFVEEVEEMLEDVARREHGDEEAADGFEEFVLQHYAGSVGKERGRKTWRQHGGGR", "length": 648, "header": "tr|A0A8V1AGC8-1|A0A8V1AI75_CHICK Computationally mapped isoform of PBX homeobox interacting protein 1 OS=Gallus gallus OX=9031 GN=PBXIP1 PE=4 SV=1 CANONICAL=A0A8V1AI75-1" }, "locus": { "chromosome": "25", "start_pos": 2016117, "end_pos": 2013480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067648.1", "url": "https://www.ensembl.org/id/ENSGALT00010067648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041391.1", "url": "https://www.ensembl.org/id/ENSGALP00010041391.1" } ] } }, { "isoform_ac": "A0A8V1AGD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75/entry#A0A8V1AGD2-1", "sequence": { "sequence": "MAQKSDSRDSDNSWVLTGTEGLPVDTVGPERDSASHEDEEEEGEEEDTPDAGTADGSEDGAASLGEKQHPEVGGAEGRSDPGAGTELPTSDPTELSATDSWEQEKHNTEPGLRAEGRTAEPLLEEGSCTSSDDDVEELRRRQVHHQPPAGTPPPAPIPRRVMQDEGNEEGLSANKLLLGALALVAVALLIVSGGFYDVADGPADVMSHDATDMEQEAVPDNGSDSPQKPPLDSGDVHSMQSMSVLLDRLAKENQDIRLMQAELQAHKEELQALLQQSEGAAAAAGAQQQSLAKENAELRAALQREAEALRAARAELQRLQARGGPGDHQPHKEQPHDPGAAVHGEGARDEARNRGLLASVRHELAAALQRARGAGGLEGLMEELRVLEERLSRELRGGEGAEAFPGHWKKGFKAEKKERGWHKRDGHRERGKAHRHGWEPHGKEPHGKEPHGKEPHSKERHGKEQHSKEPRPHREHREGKAGGKWSHGPRDHHVPPLSHSRPPQGCSGVTDCAHKEGREALGAALEPVQKAQFLQLLEGFMGRLGWGGHFGGVAERLDGAFGANGVFAHDRRRFVDFVEEVEEMLEDVARREHGDEEAADGFEEFVLQHYAGSVGKERGRKTWRQHGGGR", "length": 630, "header": "tr|A0A8V1AGD2-1|A0A8V1AI75_CHICK Computationally mapped isoform of PBX homeobox interacting protein 1 OS=Gallus gallus OX=9031 GN=PBXIP1 PE=4 SV=1 CANONICAL=A0A8V1AI75-1" }, "locus": { "chromosome": "25", "start_pos": 2016117, "end_pos": 2013480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067653.1", "url": "https://www.ensembl.org/id/ENSGALT00010067653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041396.1", "url": "https://www.ensembl.org/id/ENSGALP00010041396.1" } ] } }, { "isoform_ac": "A0A8V1AI75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75/entry#A0A8V1AI75-1", "sequence": { "sequence": "MAQKSDSRDSDNSWVLTGTEGLPVDTVGPERDSASHEDEEEEGEEEDTPDAGTADGSEDGAASLGEKQHPEVGGAEGRSDPGAGTELPTSDPTELSATDSWEQEKHNTEPGLRAEGRTAEPLLEEGSCTSSDDDVEELRRRQVHHQPPAGTPPPAPIPRRVMQDEGNEEGLSANKLLLGALALVAVALLIVSGGFYDVADGPADVMSHDATDMEQEAVPDNGSVRSGAAMGLPHPQHPQSRIPPPPPPQDSPQKPPLDSGDVHSMQSMSVLLDRLAKENQDIRLMQAELQAHKEELQALLQQSEGAAAAAGAQQQSLAKENAELRAALQREAEALRAARAELQRLQARGGPGDHQPHKEQPHDPGAAVHGEGARDEARNRGLLASVRHELAAALQRARGAGGLEGLMEELRVLEERLSRELRGGEGAEAFPGHWKKGFKAEKKERGWHKRDGHRERGKAHRHGWEPHGKEPHGKEPHGKEPHSKERHGKEQHSKEPRPHREHREGKAGGKWSHGPRDHHVPPLSHSRPPQGCSGVTDCAHKEGREALGAALEPVQKAQFLQLLEGFMGRLGWGGHFGGVAERLDGAFGANGVFAHDRRRFVDFVEEVEEMLEDVARREHGDEEAADGFEEFVLQHYAGSVGKERGRKTWRQHGGGR", "length": 656, "header": "tr|A0A8V1AI75-1|A0A8V1AI75_CHICK Isoform 1 of PBX homeobox interacting protein 1 OS=Gallus gallus OX=9031 GN=PBXIP1 PE=4 SV=1 CANONICAL=A0A8V1AI75-1" }, "locus": { "chromosome": "25", "start_pos": 2016117, "end_pos": 2013480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067651.1", "url": "https://www.ensembl.org/id/ENSGALT00010067651.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041394.1", "url": "https://www.ensembl.org/id/ENSGALP00010041394.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2VD12-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "Pbxip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASCPDSDNSWVLAGSETLPVETLGPESRVDPESEEAPQALQDSSKADGKESAGTLNGEEMLFQTESSQGEGAALPEESEAKGALGGDDGHGTKRPGDTAVQEDLQETPMVTSLGPDTQDLERNIHPQNLPSSPRAVWKEHGCSSSDDDTDVDVEGLRRRRGREPSPPQPTAAVDGEDQAKGEGIGELGISLNMCFLGALVLLGLGILLFSGALLEPETEPVEEAELQVFPETELVQTVGNRQDEVEQLQASVPPDSVPSLQSMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLLHQPKGLEEENARLREALQQGKTSHQALESELQQLRARLQGLEANCVRGVDGVCLNWGGSPQGGKATTEQGHKGQEPDTSLLEQHKQLEAEAKALRQELQKQWQLLGSVHRNLQRGLQDAGQGAPAHAGLAELGHMLAQTLQGLESQGINTGRSSNDSEAWHQKKPRFQHPREWSGREKWRGGQRDQKAEHWKLKKEESGQDRKKSWRDEGREFTGHWKENRPRAEESGSRKDSKRQDPKVHPRKSGNSHSGERQKHSWGKDNSPDSVSWEELLRRKYRPPQGCSGVADCARQEGLALFGVELAPVRQQELASVLREYLARLPWAGQLTKELPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVALKQTGDDDEVDDFEDFIFSHFFGDKALKRRSKKKEKQPWNHRAVGPREEHSRHPHHYHQG", "length": 722 }, "evidence": [ { "id": "A0A8V1AI75", "url": "https://omabrowser.org/oma/group/A0A8V1AI75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RGP4-1", "protein_name": "PBX homeobox interacting protein 1", "gene_name": "PBXIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSPDSDNSWVLAGSESLPVETLGPESRRDPEPESAPHTPQSPSKAAAEELAGTLDGEETLFQSGRSGSGPTLPEETEAKGSLEGDACGMEPPGPGDTEAQGDLEETPMVGGLGPDTQDLEDQSPPNSLPSSAKTAWLSEEVHGSSSEDDTDVDVEGLRRRRGREPSTPQPAARPGVEDLAQARGEAAGGELGISLNMWFLGALVLLGLGILLFSGGLSDSESGPVEEADLQVFPDTGSDTEILEAVGDGQDGLKQQLQASAPPDSVPSLQNMALLLDRLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENARLRGALEQGEASQRALESELQQLRAQLQGLEADCVPGTDGVCLHWGRGPQAGKVTKEQGPRGQEQGPRGQEPHPGFLEQKEQPEAEAQALRQELERQQRVLGSVQQDLERSLRDAGLAELGHRLVQKLQGLENWGQLSGVPANVSEAWRQEPHFHSSRERSGKEKWWDGQRDRKTERWKHKKEQSGWEKKKSWGGEEDKELAGRGKEGKPGVEEWAGKKDGKRQGSKEAPRKSGSPPSSSEGQKHPRWKEGAKDRPDPLSPWAELSRHKYRAPQGCSGVQECARQEGLAFFGTELAPVRQQELASLLRTYLERLPWAGQLTKELPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVAVRQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHLRNPRVVGPREEHSHHRRG", "length": 732 }, "evidence": [ { "id": "A0A8V1AI75", "url": "https://omabrowser.org/oma/group/A0A8V1AI75/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3TVI8-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "Pbxip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCPDSDNSWVLAGSENLPVETLGPEPRMDPESEGASQALRDSSKADGKELAGTLDGEEKLFQTESSQRETAVLTESAAKGTLGADGHGTEAPGDTVVQEDSQETPVATSLGPDTQDLESEIHPQNLPSSPRAVWKEHRCSSSDDDTDVDVEGLRRRRGREPSSSQPVVPVDVEDQAKGEGIGGELGISLNMCFLGALVLLGLGILLFSGTLLEPETGPMEEAELQVFPETGPETELVETLGNRQDEIEHLQASSVPPDSVPSLQSMGFLLDKLAKENQDIRLLQAQLQAQKEELQSLLHQPKGLEEENARLREALQQGKTSHQALESELQQLRARLQGLEANCVRGVDGVCLNWGGDPQDGKATKEQGHKGQEPDPSLLEQHKQLEAEAKALRQELQRQWQLLGSVHWDLQRGLRDAGRGAPAHPGLAELGHMLAQTLQDLENQGINTGRSPNDSEAWHQKKPHTQSPREWGGKEKWRGGQRDQKAEHWKPRKEESGQERQRSWRDEGREHTGRWREDRLRADESGSRKDSKRQDPKVHPRKDGNSHSVERQKHSWGKDNSPDALSSWEELLRRKYRPPQGCSGVADCARQEGLALFGVELAPVRQQELASVLREYLSRLPWAGQLTKQLPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVALKQTGDDDEVDDFEDFVFGHFFGDKALKKRSRKKEKHSWNPRVVGPREEHSRHPHHYHQG", "length": 727 }, "evidence": [ { "id": "A0A8V1AI75", "url": "https://omabrowser.org/oma/group/A0A8V1AI75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AQ6-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "PBXIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEGTLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQDLEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVENQAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFVDALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREGHSHSHHHHHRG", "length": 731 }, "evidence": [ { "id": "A0A8V1AI75", "url": "https://omabrowser.org/oma/group/A0A8V1AI75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 151 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 221, "end_pos": 223 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIF5-1", "uniprot_ac": "A0A8V1AIF5", "uniprot_id": "A0A8V1AIF5_CHICK", "mass": { "chemical_mass": 21629.0, "monoisotopic_mass": 21629.0 }, "refseq": {}, "gene_names": [ { "name": "RAC3", "type": "recommended", "evidence": [ { "id": "A0A8V1AIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8V1AIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1AIF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5", "locus": { "chromosome": "18", "start_pos": 5610964, "end_pos": 5618618, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029165", "url": "https://www.ensembl.org/id/ENSGALG00010029165" } ] } } ], "crossref": [ { "id": "A0A8V1AIF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB14", "url": "https://www.orthodb.org/?gene=A0A8V1AB14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGD1", "url": "https://www.orthodb.org/?gene=A0A8V1AGD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIF5", "url": "https://www.orthodb.org/?gene=A0A8V1AIF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIF8", "url": "https://www.orthodb.org/?gene=A0A8V1AIF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMB7", "url": "https://www.orthodb.org/?gene=A0A8V1AMB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMC2", "url": "https://www.orthodb.org/?gene=A0A8V1AMC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AB14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "EISIRCMLRWGEAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF", "length": 192, "header": "tr|A0A8V1AIF5-1|A0A8V1AIF5_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC3 PE=1 SV=1 CANONICAL=A0A8V1AIF5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#A0A8V1AB14-1", "sequence": { "sequence": "MLVTLILCRAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF", "length": 189, "header": "tr|A0A8V1AB14-1|A0A8V1AB14_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC3 PE=1 SV=1 CANONICAL=A0A8V1AIF5-1" }, "locus": { "chromosome": "18", "start_pos": 5616325, "end_pos": 5614297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070478.1", "url": "https://www.ensembl.org/id/ENSGALT00010070478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043169.1", "url": "https://www.ensembl.org/id/ENSGALP00010043169.1" } ] } }, { "isoform_ac": "A0A8V1AGD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#A0A8V1AGD1-1", "sequence": { "sequence": "MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTPGKKCTVF", "length": 175, "header": "tr|A0A8V1AGD1-1|A0A8V1AIF5_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC3 PE=1 SV=1 CANONICAL=A0A8V1AIF5-1" }, "locus": { "chromosome": "18", "start_pos": 5618484, "end_pos": 5614297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070480.1", "url": "https://www.ensembl.org/id/ENSGALT00010070480.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043171.1", "url": "https://www.ensembl.org/id/ENSGALP00010043171.1" } ] } }, { "isoform_ac": "A0A8V1AIF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#A0A8V1AIF5-1", "sequence": { "sequence": "EISIRCMLRWGEAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF", "length": 192, "header": "tr|A0A8V1AIF5-1|A0A8V1AIF5_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC3 PE=1 SV=1 CANONICAL=A0A8V1AIF5-1" }, "locus": { "chromosome": "18", "start_pos": 5616499, "end_pos": 5614297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070477.1", "url": "https://www.ensembl.org/id/ENSGALT00010070477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043168.1", "url": "https://www.ensembl.org/id/ENSGALP00010043168.1" } ] } }, { "isoform_ac": "A0A8V1AIF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#A0A8V1AIF8-1", "sequence": { "sequence": "MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIEGILPCGVPVPLPLPCSAYPKHFW", "length": 173, "header": "tr|A0A8V1AIF8-1|A0A8V1AIF8_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC3 PE=1 SV=1 CANONICAL=A0A8V1AIF5-1" }, "locus": { "chromosome": "18", "start_pos": 5618484, "end_pos": 5612334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070482.1", "url": "https://www.ensembl.org/id/ENSGALT00010070482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043173.1", "url": "https://www.ensembl.org/id/ENSGALP00010043173.1" } ] } }, { "isoform_ac": "A0A8V1AMB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#A0A8V1AMB7-1", "sequence": { "sequence": "MGGRAGPARPRPAAQASRLGGREAPDRAPRPEAGGAAGPGRHPAGPPRRLGGARGAAGRAGPGGRRSRSSAHGGSPGLRCSSGSSTRGFVSERCWASFASICVLPRERARSFGFKACLVVVSVGLSSQGGQCTASPPPHLDARRAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF", "length": 324, "header": "tr|A0A8V1AMB7-1|A0A8V1AMB7_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAC3 PE=1 SV=1 CANONICAL=A0A8V1AIF5-1" }, "locus": { "chromosome": "18", "start_pos": 5618351, "end_pos": 5614297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070479.1", "url": "https://www.ensembl.org/id/ENSGALT00010070479.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043170.1", "url": "https://www.ensembl.org/id/ENSGALP00010043170.1" } ] } }, { "isoform_ac": "A0A8V1AMC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5/entry#A0A8V1AMC2-1", "sequence": { "sequence": "PRPARAGCHCGGVAAAPPSRADAGDQVCGGGRRSCREDLLADQLHHECLSWRVHPHCDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTVF", "length": 174, "header": "tr|A0A8V1AMC2-1|A0A8V1AMC2_CHICK Computationally mapped isoform of Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) OS=Gallus gallus OX=9031 GN=RAC3 PE=1 SV=1 CANONICAL=A0A8V1AIF5-1" }, "locus": { "chromosome": "18", "start_pos": 5618548, "end_pos": 5614297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070484.1", "url": "https://www.ensembl.org/id/ENSGALT00010070484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043175.1", "url": "https://www.ensembl.org/id/ENSGALP00010043175.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "Rac protein signal transduction", "id": "GO:0016601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "cortical cytoskeleton organization", "id": "GO:0030865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "regulation of neutrophil migration", "id": "GO:1902622", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902622", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-9018804", "name": "RAC3 GEFs activate RAC3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X8M1-1", "A0A8V1AIF5-1" ], "evidence": [ { "id": "R-GGA-9018804", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9018804" } ] }, { "id": "R-GGA-9018806", "name": "RAC3 GAPs stimulate RAC3 GTPase activity", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AIF5-1", "A0A8V0YRC1-1" ], "evidence": [ { "id": "R-GGA-9018806", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9018806" } ] }, { "id": "R-GGA-9018807", "name": "RAC3 GDIs block activation of RAC3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AIF5-1" ], "evidence": [ { "id": "R-GGA-9018807", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9018807" } ] }, { "id": "R-GGA-9018808", "name": "RAC3 binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BS97-1", "E1C3P6-1", "A0A3Q2TRY2-1", "A0A8V1AIF5-1", "Q90694-1", "A0A8V0Y7Y3-1", "A0A8V0Y955-1" ], "evidence": [ { "id": "R-GGA-9018808", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9018808" } ] }, { "id": "R-GGA-9714694", "name": "RAC3 translocates to the endoplasmic reticulum membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AIF5-1" ], "evidence": [ { "id": "R-GGA-9714694", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9714694" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", 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"MAQPAHLNQNLPDLGGPFLYRDQDDSEKSSYSVETPYGFLLDLDFLKYVDDIESGQTLKKVPLPRRAKGTRLQPGTLRSPSSHPSGWTSTESLASTLSEDGRSAVLLSPHGRAVPEPPGKQTSLPTSPPPPVRLLPPPARKYLARNPQVEKTLLETSRRLEQEQSRSQPGAPSQAHPWVPAGSEGQPGSVRMSPGSSGRSTPAAGLGTAPLQHVREQMAAALRQLRELEEQVKTIPLLEMRICELQREKAKLMEKLSAEPSKVSLDHPDGSEEQPQAELEGEAEPGKGRASKIAELRKLTEKLAVPERGGRSVPGKGMAARPRAAERQCRSVAVGEERAMSDAVFYYRSQQEGGEAPEGRERRDVAVWVLESSLGLASEAETELELLQQTVGHQKDVIALMEGHLREATRELEELRMEVCARQPRSRADKEVTARPQVAEALVEAAVATQSRAAGESVQTADVAVGCAPQTACVGVGCRPRGRDVAVGPDAAVGREDKGSQADVGPADADPANTGPADPSPDNAGPTGAGPAGTGAADPPPTNTGRTDPGPAVPACEQTQPGVCDAGCRQPPPGSPAAPTPQRAAVPKAIGAAVGPAALSAEVEDGSQEPAQDGRAAPSPAARALKSIMKKRDGPPRSEAEGSKKSLQFVGVLNGEYESTSSEEEEEEEEEEEGDSSSEKASADSSDSEEPGGTDTSEEEEEDAVDGDGQSELCGQQEGEGGSMAPPEPPEVKEKFELSPRMREACLIVKTHLGHPTATKSKEVLASSSLVLQEWFRLSSQKSSVPDTVANHLLAFAELSPALLTHVVNLADGNGNTALHYSVSHSNFHIVKLLLDTGVCNVDHQNKAGYTALMLAALAAVEQEDDMNVVRRLFSMGNVNAKASQAGQTALMLAVSHGRQEMVEALLACGADVNLQDEEGSTALMCACEHGRVETVKLLLAQPTCDVSIVDSDGNNAVTIALEAGHSNIAVLLYAHLNGTKAQPQQAPRALGAQRNRIRMTFGSGCVPAGHHQSQPVTCVPSPAAPSCAESLPEAADVFHLPSTE", "length": 1045, "header": "tr|A0A8V1AIP0-1|A0A8V1AIP0_CHICK Isoform 1 of KN motif and ankyrin repeat domains 3 OS=Gallus gallus OX=9031 GN=KANK3 PE=1 SV=1 CANONICAL=A0A8V1AIP0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP0/entry#A0A8V1AGF0-1", "sequence": { "sequence": "MAQPAHLNQNLPDLGGPFLYRDQDDSEKSSYSVETPYGFLLDLDFLKYVDDIESGQTLKKVPLPRRAKGTRLQPGTLRSPSSHPSGWTSTESLASTLSEDGRSAVLLSPHGRAVPEPPGKQTSLPTSPPPPVRLLPPPARKYLARNPQVEKTLLETSRRLEQEQSRSQPGAPSQAHPWVPAGSEGQPGSVRMSPGSSGRSTPAAGLGTAPLQHVREQMAAALRQLRELEEQVKTIPLLEMRICELQREKAKLMEKLSAEPSKVSLDHPDGSEEQPQAELEGEAEPGKGRASKIAELRKLTEKLAVPERGGRSVPGKGMAARPRAAERQCRSVAVGEERAMSDAVFYYRSQQEGGEAPEGRERRDVAVWVLESSLGLASEAETELELLQQTVGHQKDVIALMEGHLREATRELEELRMEVCARQPRSRADKEVTARPQVAEALVEAAVATQSRAAGESVQTADVAVGCAPQTACVGVGCRPRGRDVAVGPDAAVGREDKGSQADVGPADADPANTGPADPSPDNAGPTGAGPAGTGAADPPPTNTGRTDPGPAVPACEQTQPGVCDAGCRQPPPGSPAAPTPQRAAVPKAIGAAVGPAALSAEVEDGSQEPAQDGRAAPSPAARALKSIMKKRDGPPRSEAEGSKKSLQFVGVLNGEYESTSSEEEEEEEEEEEGDSSSEKASADSSDSEEPGGTDTSEEEEEDAVDGDGQSELCGQQEGEGGSMAPPEPPEVKEKFELSPRMREACLIVKTHLGHPTATKSKEVLASSSLVLQEWFRLSSQKSSVPDTVANHLLAFAELSPALLTHVVNLADGNGNTALHYSVSHSNFHIVKLLLDTGVCNVDHQNKAGYTALMLAALAAVEQEDDMNVVRRLFSMGNVNAKASQAGQTALMLAVSHGRQEMVEALLACGADVNLQDEEGSTALMCACEHGRVETVKLLLAQPTCDVSIVDSDGNNAVTIALEAGHSNIAVLLYAHLNGTKAQPQQGTSTAGTKSPGSPKKPN", "length": 1003, "header": "tr|A0A8V1AGF0-1|A0A8V1AIP0_CHICK Computationally mapped isoform of KN motif and ankyrin repeat domains 3 OS=Gallus gallus OX=9031 GN=KANK3 PE=1 SV=1 CANONICAL=A0A8V1AIP0-1" }, "locus": { "chromosome": "28", "start_pos": 1297784, "end_pos": 1292989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068915.1", "url": "https://www.ensembl.org/id/ENSGALT00010068915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042357.1", "url": "https://www.ensembl.org/id/ENSGALP00010042357.1" } ] } }, { "isoform_ac": "A0A8V1AIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP0/entry#A0A8V1AIP0-1", "sequence": { "sequence": "MAQPAHLNQNLPDLGGPFLYRDQDDSEKSSYSVETPYGFLLDLDFLKYVDDIESGQTLKKVPLPRRAKGTRLQPGTLRSPSSHPSGWTSTESLASTLSEDGRSAVLLSPHGRAVPEPPGKQTSLPTSPPPPVRLLPPPARKYLARNPQVEKTLLETSRRLEQEQSRSQPGAPSQAHPWVPAGSEGQPGSVRMSPGSSGRSTPAAGLGTAPLQHVREQMAAALRQLRELEEQVKTIPLLEMRICELQREKAKLMEKLSAEPSKVSLDHPDGSEEQPQAELEGEAEPGKGRASKIAELRKLTEKLAVPERGGRSVPGKGMAARPRAAERQCRSVAVGEERAMSDAVFYYRSQQEGGEAPEGRERRDVAVWVLESSLGLASEAETELELLQQTVGHQKDVIALMEGHLREATRELEELRMEVCARQPRSRADKEVTARPQVAEALVEAAVATQSRAAGESVQTADVAVGCAPQTACVGVGCRPRGRDVAVGPDAAVGREDKGSQADVGPADADPANTGPADPSPDNAGPTGAGPAGTGAADPPPTNTGRTDPGPAVPACEQTQPGVCDAGCRQPPPGSPAAPTPQRAAVPKAIGAAVGPAALSAEVEDGSQEPAQDGRAAPSPAARALKSIMKKRDGPPRSEAEGSKKSLQFVGVLNGEYESTSSEEEEEEEEEEEGDSSSEKASADSSDSEEPGGTDTSEEEEEDAVDGDGQSELCGQQEGEGGSMAPPEPPEVKEKFELSPRMREACLIVKTHLGHPTATKSKEVLASSSLVLQEWFRLSSQKSSVPDTVANHLLAFAELSPALLTHVVNLADGNGNTALHYSVSHSNFHIVKLLLDTGVCNVDHQNKAGYTALMLAALAAVEQEDDMNVVRRLFSMGNVNAKASQAGQTALMLAVSHGRQEMVEALLACGADVNLQDEEGSTALMCACEHGRVETVKLLLAQPTCDVSIVDSDGNNAVTIALEAGHSNIAVLLYAHLNGTKAQPQQAPRALGAQRNRIRMTFGSGCVPAGHHQSQPVTCVPSPAAPSCAESLPEAADVFHLPSTE", "length": 1045, "header": "tr|A0A8V1AIP0-1|A0A8V1AIP0_CHICK Isoform 1 of KN motif and ankyrin repeat domains 3 OS=Gallus gallus OX=9031 GN=KANK3 PE=1 SV=1 CANONICAL=A0A8V1AIP0-1" }, "locus": { "chromosome": "28", "start_pos": 1297926, "end_pos": 1292989, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068914.1", "url": "https://www.ensembl.org/id/ENSGALT00010068914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042356.1", "url": "https://www.ensembl.org/id/ENSGALP00010042356.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 527, "start_aa": "Thr", "end_pos": 527, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr527", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 580, "start_aa": "Thr", "end_pos": 580, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr580", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 527, 580 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 978, "end_pos": 980 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIQ3-1", "uniprot_ac": "A0A8V1AIQ3", "uniprot_id": "A0A8V1AIQ3_CHICK", "mass": { "chemical_mass": 25140.0, "monoisotopic_mass": 25140.0 }, "refseq": {}, "gene_names": [ { "name": "C19orf60", "type": "recommended", "evidence": [ { "id": "A0A8V1AIQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3" } ] } ], "protein_names": [ { "name": "Required for excision 1-B domain containing", "type": "recommended", "evidence": [ { "id": "A0A8V1AIQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C19orf60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR039491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGG2", "url": "https://www.orthodb.org/?gene=A0A8V1AGG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIQ3", "url": "https://www.orthodb.org/?gene=A0A8V1AIQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28309:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28309:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSEAAAPLTVRFHGAGEVPTYRNRAVHVWPGSPVAVRRRSGAPWAAPARQNRARGAVRGACGSAVPAPHGPLCPCRPTRLCGRCFSASTLCRGSAWRRTGCSRSHRAYLSSAPHYDFPRYRQLVHEVTAAFSGISREVLQLQGRLRGELGRPDLAQHLTRLQEREQEKLQLTAQLQLARQRAQDEPSVDTHQQEVRELKHRLIKTIEAISEILQDLKYDSEEAE", "length": 225, "header": "tr|A0A8V1AIQ3-1|A0A8V1AIQ3_CHICK Isoform 1 of Required for excision 1-B domain containing OS=Gallus gallus OX=9031 GN=C19orf60 PE=4 SV=1 CANONICAL=A0A8V1AIQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3/entry#A0A8V1AGG2-1", "sequence": { "sequence": "MTDEALRALLQRFYALQGERVETYRLFEEGHRAYLSSAPHYDFPRYRQLVHEVTAAFSGISREVLQLQGRLRGELGRPDLAQHLTRLQEREQEKLQLTAQLQLARQRAQDEPSVDTHQQEVRELKHRSVSTPWSPPFGAGSPLHTLPFPPAGLEGAQMVPSKELLFGALRIVWRCRAAALPSASPG", "length": 186, "header": "tr|A0A8V1AGG2-1|A0A8V1AIQ3_CHICK Computationally mapped isoform of Required for excision 1-B domain containing OS=Gallus gallus OX=9031 GN=C19orf60 PE=4 SV=1 CANONICAL=A0A8V1AIQ3-1" }, "locus": { "chromosome": "28", "start_pos": 4333276, "end_pos": 4332183, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068931.1", "url": "https://www.ensembl.org/id/ENSGALT00010068931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042373.1", "url": "https://www.ensembl.org/id/ENSGALP00010042373.1" } ] } }, { "isoform_ac": "A0A8V1AIQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ3/entry#A0A8V1AIQ3-1", "sequence": { "sequence": "MVSEAAAPLTVRFHGAGEVPTYRNRAVHVWPGSPVAVRRRSGAPWAAPARQNRARGAVRGACGSAVPAPHGPLCPCRPTRLCGRCFSASTLCRGSAWRRTGCSRSHRAYLSSAPHYDFPRYRQLVHEVTAAFSGISREVLQLQGRLRGELGRPDLAQHLTRLQEREQEKLQLTAQLQLARQRAQDEPSVDTHQQEVRELKHRLIKTIEAISEILQDLKYDSEEAE", "length": 225, "header": "tr|A0A8V1AIQ3-1|A0A8V1AIQ3_CHICK Isoform 1 of Required for excision 1-B domain containing OS=Gallus gallus OX=9031 GN=C19orf60 PE=4 SV=1 CANONICAL=A0A8V1AIQ3-1" }, "locus": { "chromosome": "28", "start_pos": 4333276, "end_pos": 4332021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068930.1", "url": "https://www.ensembl.org/id/ENSGALT00010068930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042372.1", "url": "https://www.ensembl.org/id/ENSGALP00010042372.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKP8-1", "uniprot_ac": "A0A8V1AKP8", "uniprot_id": "A0A8V1AKP8_CHICK", "mass": { "chemical_mass": 130176.0, "monoisotopic_mass": 130176.0 }, "refseq": {}, "gene_names": [ { "name": "HEATR6", "type": "recommended", "evidence": [ { "id": "A0A8V1AKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8" } ] } ], "protein_names": [ { "name": "HEAT repeat-containing protein 6", "type": "recommended", "evidence": [ { "id": "A0A8V1AKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HEATR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8", "locus": { "chromosome": "19", "start_pos": 9153716, "end_pos": 9174596, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029182", "url": "https://www.ensembl.org/id/ENSGALG00010029182" } ] } } ], "crossref": [ { "id": "A0A8V1AKP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB58", "url": "https://www.orthodb.org/?gene=A0A8V1AB58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB63", "url": "https://www.orthodb.org/?gene=A0A8V1AB63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGG6", "url": "https://www.orthodb.org/?gene=A0A8V1AGG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKP8", "url": "https://www.orthodb.org/?gene=A0A8V1AKP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13366:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13366:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AB58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATAAPPVPPPPAAVAAPEVLRVAIATGPEGRKMAVVAVPAREVGPGGSFRRYLARLGALRTQPGAERSAGGRRTELHLLFDQLISENCGPAPAAGPSAQDVCVLLAQACQLVHLDQEHLVSKVCQLIHHLLNRFQVVVDEQNLNFLLSYCISALKQCSSWTHVEILQALAALVYNNGPKCQKYLQDLLGKMGLLVQFSDPAQPDMELRRAAVHSMANLCLSVPGQPCLDEPYRSVCFQTFLSVLQSSKTSNVDDIVFCMLLQNALKGIQSLLNGGKMKIMQTDQLGSLLAVLKKCMFHGLPGLSIEMPAALYPAPLPQYDKRSPVKQEQPEPAAVKPTGNRRKKSKGKQKKGEFAEEGKEDLCDTGNESNHGADVLKLNLENSPCADPRACASDVACVPAGKDPLPSHGTSWKRISSSESEYSDAEGGMQSKMRSYQAKVRQGALACFLSAIKSIEKRVLYGYWSAFVPDAPGIGSPQSVSLMTIALKDPSPKTRACSLQVLSAILEGSKQFLSIAEDANDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYSRLNPGLLTRVWNQIKPYICHKDVNVRVSSLTLLGAIVSAQAPLPEVQLLLQQPSSSGLSNSGSATPHRFNFSEQWRKALPLEGESPENPSGCLPPEPCWLIRLCISVIVLPREDSCSDSDANFPSGSVYEPSPVRLESLQVLALLVKGYFSMAQSYLLELGEVACKCMEEMDPSIQLHGAKLLEELGTGVVQQHKPDSAVAPEKRVPVSMVVTFWTMMLNGPLPGALQNSQHATLQTSACDALSSILPEAFSSLQNDQQILCITLLLGLNHSETPLVKAAAVRALGVYILFSCLRQDVMFVADTANAILNSLHDKSPSVRAKAAWSLGNLTDTLIVNMETMGQSFQEEFSDLLLLKMLRSATEASKDKDKVKSNAVRALGNLLHFLQPCHVAHPRFREAIEESLQALVSTVQSEATMKVRWNACYALGNVFKNSALPLGEAAWTTQAYSALSSVVKSCKNFKVRIKSAMALSIPSRRECYGPTEQFCQVWSALVEALQKSEDTEDFLEFKYSASLRTQICQALLHLLSLATNTDLPLIWETMRANGDAIKSYVVQYMKSGVEDNEAGMHTDLCERERLLKGAIEHLHGVEKHPECKTGGRVSVYLEGILTNHVGATELTEA", "length": 1197, "header": "tr|A0A8V1AKP8-1|A0A8V1AKP8_CHICK Isoform 1 of HEAT repeat-containing protein 6 OS=Gallus gallus OX=9031 GN=HEATR6 PE=4 SV=1 CANONICAL=A0A8V1AKP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8/entry#A0A8V1AB58-1", "sequence": { "sequence": "MAVVAVPAREVGPGGSFRRYLARLGALRTQPGAERSAGGRRTELHLLFDQLISENCGPAPAAGPSAQDVCVLLAQACQLVHLDQEHLVSKVCQLIHHLLNRFQYLQDLLGKMGLLVQFSDPAQPDMELRRAAVHSMANLCLSVPGQPCLDEPYRSVCFQTFLSVLQSSKTSNVDDIVFCMLLQNALKGIQSLLNGGKMKIMQTDQLGSLLAVLKKCMFHGLPGLSIEMPAALYPAPLPQYDKRSPVKQEQPEPAAVKPTGNRRKKSKGKQKKGEFAEEGKEDLCDTGNESNHGADVLKLNLENSPCADPRACASDVACVPAGKDPLPSHGTSWKRISSSESEYSDAEGGMQSKMRSYQAKVRQGALACFLSAIKSIEKRVLYGYWSAFVPDAPGIGSPQSVSLMTIALKDPSPKTRACSLQVLSAILEGSKQFLSIAEDANDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYSRLNPGLLTRVWNQIKPYICHKDVNVRVSSLTLLGAIVSAQAPLPEVQLLLQQPSSSGLSNSGSATPHRFNFSEQWRKALPLEGESPENPSGCLPPEPCWLIRLCISVIVLPREDSCSDSDANFPSGSVYEPSPVRLESLQVLALLVKGYFSMAQSYLLELGEVACKCMEEMDPSIQLHGAKLLEELGTGVVQQHKPDSAVAPEKRVPVSMVVTFWTMMLNGPLPGALQNSQHATLQTSACDALSSILPEAFSSLQNDQQILCITLLLGLNHSETPLVKAAAVRALGVYILFSCLRQDVMFVADTANAILNSLHDKSPSVRAKAAWSLGNLTDTLIVNMETMGQSFQEEFSDLLLLKMLRSATEASKDKDKVKSNAVRALGNLLHFLQPCHVAHPRFREAIEESLQALVSTVQSEATMKVRWNACYALGNVFKNSALPLGEAAWTTQAYSALSSVVKSCKNFKVRIKSAMALSIPSRRECYGPTEQFCQVWSALVEALQKSEDTEDFLEFKYSASLRTQICQALLHLLSLATNTDLPLIWETMRANGDAIKSYVVQYMKSGVEDNEAGMHTDLCERERLLKGAIEHLHGVEKHPECKTGGRVSVYLEGILTNHVGATELTEA", "length": 1116, "header": "tr|A0A8V1AB58-1|A0A8V1AB58_CHICK Computationally mapped isoform of HEAT repeat-containing protein 6 OS=Gallus gallus OX=9031 GN=HEATR6 PE=4 SV=1 CANONICAL=A0A8V1AKP8-1" }, "locus": { "chromosome": "19", "start_pos": 9169056, "end_pos": 9154626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070519.1", "url": "https://www.ensembl.org/id/ENSGALT00010070519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043210.1", "url": "https://www.ensembl.org/id/ENSGALP00010043210.1" } ] } }, { "isoform_ac": "A0A8V1AB63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8/entry#A0A8V1AB63-1", "sequence": { "sequence": "MPQSINCVCAGEASSKLECLLSVRKNTELFGNIWIWSSEWRDVCVLLAQACQLVHLDQEHLVSKVCQLIHHLLNRFQVVVDEQNLNFLLSYCISALKQCSSWTHVEILQALAALVYNNGPKCQKYLQDLLGKMGLLVQFSDPAQPDMELRRAAVHSMANLCLSVPGQPCLDEPYRSVCFQTFLSVLQSSKTSNVDDIVFCMLLQNALKGIQSLLNGGKMKIMQTDQLGSLLAVLKKCMFHGLPGLSIEMPAALYPAPLPQYDKRSPVKQEQPEPAAVKPTGNRRKKSKGKQKKGEFAEEGKEDLCDTGNESNHGADVLKLNLENSPCADPRACASDVACVPAGKDPLPSHGTSWKRISSSESEYSDAEGGMQSKMRSYQAKVRQGALACFLSAIKSIEKRVLYGYWSAFVPDAPGIGSPQSVSLMTIALKDPSPKTRACSLQVLSAILEGSKQFLSIAEDANDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYSRLNPGLLTRVWNQIKPYICHKDVNVRVSSLTLLGAIVSAQAPLPEVQLLLQQPSSSGLSNSGSATPHRFNFSEQWRKALPLEGESPENPSGCLPPEPCWLIRLCISVIVLPREDSCSDSDANFPSGSVYEPSPVRLESLQVLALLVKGYFSMAQSYLLELGEVACKCMEEMDPSIQLHGAKLLEELGTGVVQQHKPDSAVAPEKRVPVSMVVTFWTMMLNGPLPGALQNSQHATLQTSACDALSSILPEAFSSLQNDQQILCITLLLGLNHSETPLVKAAAVRALGVYILFSCLRQDVMFVADTANAILNSLHDKSPSVRAKAAWSLGNLTDTLIVNMETMGQSFQEEFSDLLLLKMLRSATEASKDKDKVKSNAVRALGNLLHFLQPCHVAHPRFREAIEESLQALVSTVQSEATMKVRWNACYALGNVFKNSALPLGEAAWTTQAYSALSSVVKSCKNFKVRIKSAMALSIPSRRECYGPTEQFCQVWSALVEALQKSEDTEDFLEFKYSASLRTQICQALLHLLSLATNTDLPLIWETMRANGDAIKSYVVQYMKSGVEDNEAGMHTDLCERERLLKGAIEHLHGVEKHPECKTGGRVSVYLEGILTNHVGATELTEA", "length": 1137, "header": "tr|A0A8V1AB63-1|A0A8V1AB63_CHICK Computationally mapped isoform of HEAT repeat-containing protein 6 OS=Gallus gallus OX=9031 GN=HEATR6 PE=4 SV=1 CANONICAL=A0A8V1AKP8-1" }, "locus": { "chromosome": "19", "start_pos": 9174484, "end_pos": 9154626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070524.1", "url": "https://www.ensembl.org/id/ENSGALT00010070524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043215.1", "url": "https://www.ensembl.org/id/ENSGALP00010043215.1" } ] } }, { "isoform_ac": "A0A8V1AGG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8/entry#A0A8V1AGG6-1", "sequence": { "sequence": "MAVVAVPAREVGPGGSFRRYLARLGALRTQPGAERSAGGRRTELHLLFDQLISENCGPAPAAGPSAQDVCVLLAQACQLVHLDQEHLVSKVCQLIHHLLNRFQVVVDEQNLNFLLSYCISALKQCSSWTHVEILQALAALVYNNGPKCQKVVPGQPCLDEPYRSVCFQTFLSVLQSSKTSNVDDIVFCMLLQNALKGIQSLLNGGKMKIMQTDQLGSLLAVLKKCMFHGLPGLSIEMPAALYPAPLPQYDKRSPVKQEQPEPAAVKPTGNRRKKSKGKQKKGEFAEEGKEDLCDTGNESNHGADVLKLNLENSPCADPRACASDVACVPAGKDPLPSHGTSWKRISSSESEYSDAEGGMQSKMRSYQAKVRQGALACFLSAIKSIEKRVLYGYWSAFVPDAPGIGSPQSVSLMTIALKDPSPKTRACSLQVLSAILEGSKQFLSIAEDANDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYSRLNPGLLTRVWNQIKPYICHKDVNVRVSSLTLLGAIVSAQAPLPEVQLLLQQPSSSGLSNSGSATPHRFNFSEQWRKALPLEGESPENPSGCLPPEPCWLIRLCISVIVLPREDSCSDSDANFPSGSVYEPSPVRLESLQVLALLVKGYFSMAQSYLLELGEVACKCMEEMDPSIQLHGAKLLEELGTGVVQQHKPDSAVAPEKRVPVSMVVTFWTMMLNGPLPGALQNSQHATLQTSACDALSSILPEAFSSLQNDQQILCITLLLGLNHSETPLVKAAAVRALGVYILFSCLRQDVMFVADTANAILNSLHDKSPSVRAKAAWSLGNLTDTLIVNMETMGQSFQEEFSDLLLLKMLRSATEASKDKDKVKSNAVRALGNLLHFLQPCHVAHPRFREAIEESLQALVSTVQSEATMKVRWNACYALGNVFKNSALPLGEAAWTTQAYSALSSVVKSCKNFKVRIKSAMALSIPSRRECYGPTEQFCQVWSALVEALQKSEDTEDFLEFKYSASLRTQICQALLHLLSLATNTDLPLIWETMRANGDAIKSYVVQYMKSGVEDNEAGMHTDLCERERLLKGAIEHLHGVEKHPECKTGGRVSVYLEGILTNHVGATELTEA", "length": 1125, "header": "tr|A0A8V1AGG6-1|A0A8V1AKP8_CHICK Computationally mapped isoform of HEAT repeat-containing protein 6 OS=Gallus gallus OX=9031 GN=HEATR6 PE=4 SV=1 CANONICAL=A0A8V1AKP8-1" }, "locus": { "chromosome": "19", "start_pos": 9169056, "end_pos": 9154626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070516.1", "url": "https://www.ensembl.org/id/ENSGALT00010070516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043207.1", "url": "https://www.ensembl.org/id/ENSGALP00010043207.1" } ] } }, { "isoform_ac": "A0A8V1AKP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8/entry#A0A8V1AKP8-1", "sequence": { "sequence": "MAATAAPPVPPPPAAVAAPEVLRVAIATGPEGRKMAVVAVPAREVGPGGSFRRYLARLGALRTQPGAERSAGGRRTELHLLFDQLISENCGPAPAAGPSAQDVCVLLAQACQLVHLDQEHLVSKVCQLIHHLLNRFQVVVDEQNLNFLLSYCISALKQCSSWTHVEILQALAALVYNNGPKCQKYLQDLLGKMGLLVQFSDPAQPDMELRRAAVHSMANLCLSVPGQPCLDEPYRSVCFQTFLSVLQSSKTSNVDDIVFCMLLQNALKGIQSLLNGGKMKIMQTDQLGSLLAVLKKCMFHGLPGLSIEMPAALYPAPLPQYDKRSPVKQEQPEPAAVKPTGNRRKKSKGKQKKGEFAEEGKEDLCDTGNESNHGADVLKLNLENSPCADPRACASDVACVPAGKDPLPSHGTSWKRISSSESEYSDAEGGMQSKMRSYQAKVRQGALACFLSAIKSIEKRVLYGYWSAFVPDAPGIGSPQSVSLMTIALKDPSPKTRACSLQVLSAILEGSKQFLSIAEDANDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYSRLNPGLLTRVWNQIKPYICHKDVNVRVSSLTLLGAIVSAQAPLPEVQLLLQQPSSSGLSNSGSATPHRFNFSEQWRKALPLEGESPENPSGCLPPEPCWLIRLCISVIVLPREDSCSDSDANFPSGSVYEPSPVRLESLQVLALLVKGYFSMAQSYLLELGEVACKCMEEMDPSIQLHGAKLLEELGTGVVQQHKPDSAVAPEKRVPVSMVVTFWTMMLNGPLPGALQNSQHATLQTSACDALSSILPEAFSSLQNDQQILCITLLLGLNHSETPLVKAAAVRALGVYILFSCLRQDVMFVADTANAILNSLHDKSPSVRAKAAWSLGNLTDTLIVNMETMGQSFQEEFSDLLLLKMLRSATEASKDKDKVKSNAVRALGNLLHFLQPCHVAHPRFREAIEESLQALVSTVQSEATMKVRWNACYALGNVFKNSALPLGEAAWTTQAYSALSSVVKSCKNFKVRIKSAMALSIPSRRECYGPTEQFCQVWSALVEALQKSEDTEDFLEFKYSASLRTQICQALLHLLSLATNTDLPLIWETMRANGDAIKSYVVQYMKSGVEDNEAGMHTDLCERERLLKGAIEHLHGVEKHPECKTGGRVSVYLEGILTNHVGATELTEA", "length": 1197, "header": "tr|A0A8V1AKP8-1|A0A8V1AKP8_CHICK Isoform 1 of HEAT repeat-containing protein 6 OS=Gallus gallus OX=9031 GN=HEATR6 PE=4 SV=1 CANONICAL=A0A8V1AKP8-1" }, "locus": { "chromosome": "19", "start_pos": 9169158, "end_pos": 9154626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070522.1", "url": "https://www.ensembl.org/id/ENSGALT00010070522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043213.1", "url": "https://www.ensembl.org/id/ENSGALP00010043213.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP8" }, { "id": "PF13251", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13251" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4042", "eco_id": "ECO_0000259", "start_pos": 441, "end_pos": 622, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 369, "end_pos": 371 }, { "start_pos": 646, "end_pos": 648 }, { "start_pos": 846, "end_pos": 848 }, { "start_pos": 905, "end_pos": 907 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIK1-1", "uniprot_ac": "A0A8V1AIK1", "uniprot_id": "A0A8V1AIK1_CHICK", "mass": { "chemical_mass": 70571.0, "monoisotopic_mass": 70571.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF606", "type": "recommended", "evidence": [ { "id": "A0A8V1AIK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ] } ], "protein_names": [ { "name": "Zinc finger protein 606", "type": "synonym", "evidence": [ { "id": "A0A8V1AIK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF606", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859497", "url": "https://www.ncbi.nlm.nih.gov/gene/100859497", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859497", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859497", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNSCDEC", "url": "https://omabrowser.org/oma/group/QNSCDEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGH0", "url": "https://www.orthodb.org/?gene=A0A8V1AGH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGH5", "url": "https://www.orthodb.org/?gene=A0A8V1AGH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIJ6", "url": "https://www.orthodb.org/?gene=A0A8V1AIJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIK1", "url": "https://www.orthodb.org/?gene=A0A8V1AIK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIK6", "url": "https://www.orthodb.org/?gene=A0A8V1AIK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKP2", "url": "https://www.orthodb.org/?gene=A0A8V1AKP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKQ2", "url": "https://www.orthodb.org/?gene=A0A8V1AKQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AME8", "url": "https://www.orthodb.org/?gene=A0A8V1AME8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELFFSSETAPQLQFRGLSVVVVLSRKRRTTPSPRGLCVSVPKESYNCSQITGRPCFFPFRSCRQRVRSPTVSRSASDRLQLHFCLSPVVISACRKAGNDHRASISGACELCGGGGVFQQGGVGAAGPCTVSALPGCYAGDCVASLAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 625, "header": "tr|A0A8V1AIK1-1|A0A8V1AIK1_CHICK Isoform 1 of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AGH0-1", "sequence": { "sequence": "MSVQGEPQEAPLLKGSLHCAAHGSAGESGACELCGGGGVFQQGGVGAAGPCTVSALPGCYAGDCVASLAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 547, "header": "tr|A0A8V1AGH0-1|A0A8V1AIK1_CHICK Computationally mapped isoform of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 667456, "end_pos": 664578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070521.1", "url": "https://www.ensembl.org/id/ENSGALT00010070521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043212.1", "url": "https://www.ensembl.org/id/ENSGALP00010043212.1" } ] } }, { "isoform_ac": "A0A8V1AGH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AGH5-1", "sequence": { "sequence": "MNGGGTHSSACLSLRAVTGRGCCVQARRKEEGGRKKEGQRGEHTGFAVEEACRLQLHFCLSPVVISACRKAGNDHRASISGACELCGGGGVFQQGGVGAAGPCTVSALPGCYAGDCVASLAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 599, "header": "tr|A0A8V1AGH5-1|A0A8V1AIK1_CHICK Computationally mapped isoform of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 674056, "end_pos": 664578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070526.1", "url": "https://www.ensembl.org/id/ENSGALT00010070526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043217.1", "url": "https://www.ensembl.org/id/ENSGALP00010043217.1" } ] } }, { "isoform_ac": "A0A8V1AIJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AIJ6-1", "sequence": { "sequence": "MAVSSVTLSAHVKPHGVLVEACPFSNRHRLQLHFCLSPVVISACRKAGNDHRASISAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 535, "header": "tr|A0A8V1AIJ6-1|A0A8V1AIJ6_CHICK Computationally mapped isoform of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 668407, "end_pos": 664578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070518.1", "url": "https://www.ensembl.org/id/ENSGALT00010070518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043209.1", "url": "https://www.ensembl.org/id/ENSGALP00010043209.1" } ] } }, { "isoform_ac": "A0A8V1AIK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AIK1-1", "sequence": { "sequence": "MELFFSSETAPQLQFRGLSVVVVLSRKRRTTPSPRGLCVSVPKESYNCSQITGRPCFFPFRSCRQRVRSPTVSRSASDRLQLHFCLSPVVISACRKAGNDHRASISGACELCGGGGVFQQGGVGAAGPCTVSALPGCYAGDCVASLAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 625, "header": "tr|A0A8V1AIK1-1|A0A8V1AIK1_CHICK Isoform 1 of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 671157, "end_pos": 664578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070523.1", "url": "https://www.ensembl.org/id/ENSGALT00010070523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043214.1", "url": "https://www.ensembl.org/id/ENSGALP00010043214.1" } ] } }, { "isoform_ac": "A0A8V1AIK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AIK6-1", "sequence": { "sequence": "MTGELSTGEVGGKRGGWGWPKPSLAWRYFGYCVLFLDFFCHHAGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 485, "header": "tr|A0A8V1AIK6-1|A0A8V1AIK6_CHICK Computationally mapped isoform of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 650474, "end_pos": 649020, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070528.1", "url": "https://www.ensembl.org/id/ENSGALT00010070528.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043219.1", "url": "https://www.ensembl.org/id/ENSGALP00010043219.1" } ] } }, { "isoform_ac": "A0A8V1AKP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AKP2-1", "sequence": { "sequence": "MSVQGEPQEAPLLKGSLHCAAHGSAGESGCCVQARRKEEGGRKKEGQRGEHTGFAVEEACRLQLHFCLSPVVISACRKAGNDHRASISGACELCGGGGVFQQGGVGAAGPCTVSALPGCYAGDCVASLAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 607, "header": "tr|A0A8V1AKP2-1|A0A8V1AKP2_CHICK Computationally mapped isoform of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 667456, "end_pos": 664578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070517.1", "url": "https://www.ensembl.org/id/ENSGALT00010070517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043208.1", "url": "https://www.ensembl.org/id/ENSGALP00010043208.1" } ] } }, { "isoform_ac": "A0A8V1AKQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AKQ2-1", "sequence": { "sequence": "MNGGGTHSSACLSLRAVTGRGCCVQARRKEEGGRKKEGQRGEHTGFAVEEACRLQLHFCLSPVVISACRKAGNDHRASISAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 559, "header": "tr|A0A8V1AKQ2-1|A0A8V1AKQ2_CHICK Computationally mapped isoform of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 674056, "end_pos": 664578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070527.1", "url": "https://www.ensembl.org/id/ENSGALT00010070527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043218.1", "url": "https://www.ensembl.org/id/ENSGALP00010043218.1" } ] } }, { "isoform_ac": "A0A8V1AME8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1/entry#A0A8V1AME8-1", "sequence": { "sequence": "MGLKWRMWEAMWRTSLEDITPNIDWNLYPRSSNAKGDKNRLQLHFCLSPVVISACRKAGNDHRASISGACELCGGGGVFQQGGVGAAGPCTVSALPGCYAGDCVASLAPLPVPNPVVITLLEGDEDLWISDVCSPKEMTGELSTGDRITTIKEDVQKSGVSRRHSGCVSVGESRMDVQGGLEQGEPLGNHLGKTAKNPLDLSTAQKQHEEVRSKEVCQKRRQNPCDECGKSCERCSVGFKHQCIHSKETLYKCPDCAKCFKWRSTLTYHQRVHTGERPFKCPQCGKSFKNNFGLIRHQRIHTGERPYSCPQCPQSFRSSSHLNRHQRIHTGERPYKCLECEKSFRSNSDLTYHQRIHTGERPYKCHECGKSFKSNSELVHHQRIHTGERPYKCTECGKGFKSNSDLIRHQLVHTGERPYKCPECEKSFRSISALICHQHVHPGERPYKCHECGKSFKSDSELVHHQHIHTGERPYKCPECGKTFKRNSHLTYHQRTHTGERPYKCNECGKGFTSSSDLIVHHRIHTGERPFKCPECEKSFKRSSDLIYHQHIHTGETPYKCPECGKGFRRSSNLSSHKRIHREDQL", "length": 586, "header": "tr|A0A8V1AME8-1|A0A8V1AME8_CHICK Computationally mapped isoform of Zinc finger protein 606 OS=Gallus gallus OX=9031 GN=ZNF606 PE=3 SV=1 CANONICAL=A0A8V1AIK1-1" }, "locus": { "chromosome": "18", "start_pos": 669695, "end_pos": 664578, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070520.1", "url": "https://www.ensembl.org/id/ENSGALT00010070520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043211.1", "url": "https://www.ensembl.org/id/ENSGALP00010043211.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859497", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859497", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK1" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 317, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 47, "end_pos": 49 }, { "start_pos": 612, "end_pos": 614 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIG5-1", "uniprot_ac": "A0A8V1AIG5", "uniprot_id": "A0A8V1AIG5_CHICK", "mass": { "chemical_mass": 123310.0, "monoisotopic_mass": 123310.0 }, "refseq": {}, "gene_names": [ { "name": "KIAA1257", "type": "recommended", "evidence": [ { "id": "A0A8V1AIG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 92 (putative)", "type": "synonym", "evidence": [ { "id": "A0A8V1AIG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA1257", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR027876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33667", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33667", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33667:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33667:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28322", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28322", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A6F9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6F9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE37", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTNPPDRRGKGAPADELKTKRCYCIECFLLPDDLVPRKMDLVVVGMVAKLFAESDSKTIMPWLENDQMWISWSHNTNVNVTNEFLVKLRDHKITLKLWDTKDQVFSEARLTKPDVSSIEDEEAVDGVKHTVLQQRRLFEGSQPAPSCTKIREAKESKAQKESSALPIKEETDQSGLGTSSCNVLHPPKTDDSTVRFEGNAQLLKQKAVAAPSHNAASEETGETASNVGIPMCQTDKTATFNGENSVISRLEENSPILLDAYVSFTVETPLLSERQIRELNPLVIKICSATSLPNTPVPIEVLQKLCVPTYCKYKFHNFPAHQTHGQIHGTHVYFKDVNVFLTGRMKPGELQRCLRGPPLEIEVHDRDRKIEDNKKEPCLFGEDHTDENLGELRPLPCQSAICNSFAEDEVWHPHGVAKVSLSDLLLGKKYLTVSAPIRSCSTPNTAAFNKKNKRKKIGKKHPQILLPMGHYLQSDSLLKLRVEIAVPLRMHAEIDDAQVTDCPYSCIVYIFDYSNSFLLHDLVEEITEINAKALQLDCYPPHLIRTSLATLKLKSTLEKVSELDVVTGFHLLDGATHLFVLEGLKDKAIKRLWDRHFERTYRHEDGQLEILYNSQLSFSQRLYTNLEAIFYRFHLCKPLFTILKQPLLYVRGAVPWACFQALSRLSYLCHSKRLRDVIQGDLLPSAEMITALSREYGVPLADEDLFTQKPPLLLFSSDYTPPGNVSREKKARYSSLDHYNERYVLWKKEIADKKSFERNHIRANIDAVRQLKGKMKRLKFETFRIFPADGKSVYNYSSQRLNSAELAKKHLRQEMAKDPKTRFSYCHEYLSATFDPVDVVAACKESFAKSKSMWLSPDGFVFAGFKSSIESNLHPRMPDEARVEELREKWQENALFANMAPVLPRGRWSWDKRHVDFELYKKPPELPMATAALTAAELCAREPGATSELQQLQGLLKDEPLKFPLRKPGLILKPNPALSVLDSQNSSDVLPGKKSVCSGFVPGLQDHHSRKWNKNIIPWHNREHKKIEKLEGADFNLLGSKQSVYKSDQAASKHATTYAQQEDPLQNDILDTGNSVNTRECVTGQN", "length": 1087, "header": "tr|A0A8V1AIG5-1|A0A8V1AIG5_CHICK Isoform 1 of Cilia and flagella associated protein 92 (putative) OS=Gallus gallus OX=9031 GN=KIAA1257 PE=4 SV=1 CANONICAL=A0A8V1AIG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5/entry#A0A8V1A6F9-1", "sequence": { "sequence": "MGTDTAQHYGVTAEFQTVYLEQPCVHNTVRERRRTYLECPYLSCRRGDTVAVRTRCKESISTETHSIPPAVPLISRIPGGSGSVTSEQKQMTTNPPDRRGKGAPADELKTKRCYCIECFLLPDDLVPRKMDLVVVGMVAKLFAESDSKTIMPWLENDQMWISWSHNTNVNVTNEFLVKLRDHKITLKLWDTKDQVFSEARLTKPDVSSIEDEEAVDGVKHTVLQQRRLFEGSQPAPSCTKIREAKESKAQKESSALPIKEETDQSGLGTSSCNVLHPPKTDDSTVRNRFEGNAQLLKQKAVAAPSHNAASEETGETASNVGIPMCQTDKTATFNGRRDSGAKKGMDTTRANIASLQLDLMPLLSGENSVISRLEENSPILLDAYVSFTVETPLLSERQIRELNPLVIKICSATSLPNTPVPIEVLQKLCVPTYCKYKFHNFPAHQTHGQIHGTHVYFKDVNVFLTGRMKPGELQRCLRGPPLEIEVHDRDRKIEDNKKEPCLFGEDHTDENLGELRPLPCQSAICNSFAEDEVWHPHGVAKVSLSDLLLGKKYLTVSAPIRSCSTPNTAAFNKKNKRKKIGKKHPQILLPMGHYLQSDSLLKLRVEIAVPLRMHAEIDDAQVTDCPYSCIVYIFDYSNSFLLHDLVEEITEINAKALQLDCYPPHLIRTSLATLKLKSTLEKVSELDVVTGFHLLDGATHLFVLEGLKDKAIKRLWDRHFERTYRHEDGQLEILYNSQLSFSQRLYTNLEAIFYRFHLCKPLFTILKQPLLYVRGAVPWACFQALSRLSYLCHSKRLRDVIQGDLLPSAEMITALSREYGVPLADEDLFTQKPPLLLFSSDYTPPGNVSREKKARYSSLDHYNERYVLWKKEIADKKSFERNHIRANIDAVRQLKGKMKRLKFETFRIFPADGKSVYNYSSQRLNSAELAKKHLRQEMAKDPKTRFSYCHEYLSATFDPVDVVAACKESFAKSKSMWLSPDGFVFAGFKSSIESNLHPRMPDEARVEELREVTEY", "length": 1015, "header": "tr|A0A8V1A6F9-1|A0A8V1A6F9_CHICK Computationally mapped isoform of Cilia and flagella associated protein 92 (putative) OS=Gallus gallus OX=9031 GN=KIAA1257 PE=4 SV=1 CANONICAL=A0A8V1AIG5-1" }, "locus": { "chromosome": "12", "start_pos": 5398583, "end_pos": 5340088, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067763.1", "url": "https://www.ensembl.org/id/ENSGALT00010067763.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041506.1", "url": "https://www.ensembl.org/id/ENSGALP00010041506.1" } ] } }, { "isoform_ac": "A0A8V1AE33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5/entry#A0A8V1AE33-1", "sequence": { "sequence": "MTTNPPDRRGKGAPADELKTKRCYCIECFLLPDDLVPRKMDLVVVGMVAKLFAESDSKTIMPWLENDQMWISWSHNTNVNVTNEFLVKLRDHKITLKLWDTKDQVFSEARLTKPDVSSIEDEEAVEETDQSGLGTSSCNVLHPPKTDDSTVRFEGNAQLLKQKAVAAPSHNAASEETGETASNVGIPMCQTDKTATFNGRRDSGAKKGMDTTRANIASLQLDLMPLLSGENSVISRLEENSPILLDAYVSFTVETPLLSERQIRELNPLVIKICSATSLPNTPVPIEVLQKLCVPTYCKYKFHNFPAHQTHGQIHGTHVYFKDVNVFLTGRMKPGELQRCLRGPPLEIEVHDRDRKIEDNKKEPCLFGEDHTDENLGELRPLPCQSAICNSFAEDEVWHPHGVAKVSLSDLLLGKKYLTVSAPIRSCSTPNTAAFNKKNKRKKIGKKHPQILLPMGHYLQSDSLLKLRVEIAVPLRMHAEIDDAQVTDCPYSCIVYIFDYSNSFLLHDLVEEITEINAKALQLDCYPPHLIRTSLATLKLKSTLEKVSELDVVTGFHLLDGATHLFVLEGLKDKAIKRLWDRHFERTYRHEDGQLEILYNSQLSFSQRLYTNLEAIFYRFHLCKPLFTILKQPLLYVRGAVPWACFQALSRLSYLCHSKRLRDVIQGDLLPSAEMITALSREYGVPLADEDLFTQKPPLLLFSSDYTPPGNVSREKKARYSSLDHYNERYVLWKKEIADKKSFERNHIRANIDAVRQLKGKMKRLKFETFRIFPADGKSVYNYSSQRLNSAELAKKHLRQEMAKDPKTRFSYCHEYLSATFDPVDVVAACKESFAKSKSMWLSPDGFVFAGFKSSIESNLHPRMPDEARVEELREKWQENALFANMAPVLPRGRWSWDKRHVDFELYKKPPELPMATAALTAAELCAREPGATSELQQLQGLLKDEPLKFPLRKPGLILKPNPALSVLDSQNSSDVLPGKKSVCSGFVPGLQDHHSRKWNKNIIPWHNREHKKIEKLEGADFNLLGSKQSVYKSDQAASKHATTYAQQEDPLQNDILDTGNSVNTRECVTGQN", "length": 1073, "header": "tr|A0A8V1AE33-1|A0A8V1AE33_CHICK Computationally mapped isoform of Cilia and flagella associated protein 92 (putative) OS=Gallus gallus OX=9031 GN=KIAA1257 PE=4 SV=1 CANONICAL=A0A8V1AIG5-1" }, "locus": { "chromosome": "12", "start_pos": 5403720, "end_pos": 5381317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067757.1", "url": "https://www.ensembl.org/id/ENSGALT00010067757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041500.1", "url": "https://www.ensembl.org/id/ENSGALP00010041500.1" } ] } }, { "isoform_ac": "A0A8V1AE37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5/entry#A0A8V1AE37-1", "sequence": { "sequence": "MPWLENDQMWISWSHNTNVNVTNEFLVKLRDHKITLKLWDTKDQVFSEARLTKPDVSSIEDEEAVDGVKHTVLQQRRLFEGSQPAPSCTKIREAKESKAQKESSALPIKEETDQSGLGTSSCNVLHPPKTDDSTVRFEGNAQLLKQKAVAAPSHNAASEETGETASNVGIPMCQTDKTATFNGRRDSGAKKGMDTTRANIASLQLDLMPLLSGENSVISRLEENSPILLDAYVSFTVETPLLSERQIRELNPLVIKICSATSLPNTPVPIEVLQKLCVPTYCKYKFHNFPAHQTHGQIHGTHVYFKDVNVFLTGRMKPGELQRCLRGPPLEIEVHDRDRKIEDNKKEPCLFGEDHTDENLGELRPLPCQSAICNSFAEDEVWHPHGVAKVSLSDLLLGKKYLTVSAPIRSCSTPNTAAFNKKNKRKKIGKKHPQILLPMGHYLQSDSLLKLRVEIAVPLRMHAEIDDAQVTDCPYSCIVYIFDYSNSFLLHDLVEEITEINAKALQLDCYPPHLIRTSLATLKLKSTLEKVSELDVVTGFHLLDGATHLFVLEGLKDKAIKRLWDRHFERTYRHEDGQLEILYNSQLSFSQRLYTNLEAIFYRFHLCKPLFTILKQPLLYVRGAVPWACFQALSRLSYLCHSKRLRDVIQGDLLPSAEMITALSREYGVPLADEDLFTQKPPLLLFSSDYTPPGNVSREKKARYSSLDHYNERYVLWKKEIADKKSFERNHIRANIDAVRQLKGKMKRLKFETFRIFPADGKSVYNYSSQRLNSAELAKKHLRQEMAKDPKTRFSYCHEYLSATFDPVDVVAACKESFAKSKSMWLSPDGFVFAGFKSSIESNLHPRMPDEARVEELREKWQENALFANMAPVLPRGRWSWDKRHVDFELYKKPPELPMATAALTAAELCAREPGATSELQQLQGLLKDEPLKFPLRKPGLILKPNPALSVLDSQNSSDVLPGKKSVCSGFVPGLQDHHSRKWNKNIIPWHNREHKKIEKLEGADFNLLGSKQSVYKSDQAASKHATTYAQQEDPLQNDILDTATASQRWDDPLTGH", "length": 1057, "header": "tr|A0A8V1AE37-1|A0A8V1AE37_CHICK Computationally mapped isoform of Cilia and flagella associated protein 92 (putative) OS=Gallus gallus OX=9031 GN=KIAA1257 PE=4 SV=1 CANONICAL=A0A8V1AIG5-1" }, "locus": { "chromosome": "12", "start_pos": 5405078, "end_pos": 5383296, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067762.1", "url": "https://www.ensembl.org/id/ENSGALT00010067762.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041505.1", "url": "https://www.ensembl.org/id/ENSGALP00010041505.1" } ] } }, { "isoform_ac": "A0A8V1AGL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5/entry#A0A8V1AGL2-1", "sequence": { "sequence": "MEEGGGEELGTARAESGCGGSERGSSPAEGARQLSSPRSVPCVLTVSLSIPALATKQKQMTTNPPDRRGKGAPADELKTKRCYCIECFLLPDDLVPRKMDLVVVGMVAKLFAESDSKTIMPWLENDQMWISWSHNTNVNVTNEFLVKLRDHKITLKLWDTKDQVFSEARLTKPDVSSIEDEEAVEETDQSGLGTSSCNVLHPPKTDDSTVRFEGNAQLLKQKAVAAPSHNAASEETGETASNVGIPMCQTDKTATFNGRRDSGAKKGMDTTRANIASLQLDLMPLLSGENSVISRLEENSPILLDAYVSFTVETPLLSERQIRELNPLVIKICSATSLPNTPVPIEVLQKLCVPTYCKYKFHNFPAHQTHGQIHGTHVYFKDVNVFLTGRMKPGELQRCLRGPPLEIEVHDRDRKIEDNKKEPCLFGEDHTDENLGELRPLPCQSAICNSFAEDEVWHPHGVAKVSLSDLLLGKKYLTVSAPIRSCSTPNTAAFNKKNKRKKIGKKHPQILLPMGHYLQSDSLLKLRVEIAVPLRMHAEIDDAQVTDCPYSCIVYIFDYSNSFLLHDLVEEITEINAKALQLDCYPPHLIRTSLATLKLKSTLEKVSELDVVTGFHLLDGATHLFVLEGLKDKAIKRLWDRHFERTYRHEDGQLEILYNSQLSFSQRLYTNLEAIFYRFHLCKPLFTILKQPLLYVRGAVPWACFQALSRLSYLCHSKRLRDVIQGDLLPSAEMITALSREYGVPLADEDLFTQKPPLLLFSSDYTPPGNVSREKKARYSSLDHYNERYVLWKKEIADKKSFERNHIRANIDAVRQLKGKMKRLKFETFRIFPADGKSVYNYSSQRLNSAELAKKHLRQEMAKDPKTRFSYCHEYLSATFDPVDVVAACKESFAKSKSMWLSPDGFVFAGFKSSIESNLHPRMPDEARVEELREVTEY", "length": 938, "header": "tr|A0A8V1AGL2-1|A0A8V1AIG5_CHICK Computationally mapped isoform of Cilia and flagella associated protein 92 (putative) OS=Gallus gallus OX=9031 GN=KIAA1257 PE=4 SV=1 CANONICAL=A0A8V1AIG5-1" }, "locus": { "chromosome": "12", "start_pos": 5398583, "end_pos": 5380387, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067751.1", "url": "https://www.ensembl.org/id/ENSGALT00010067751.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041494.1", "url": "https://www.ensembl.org/id/ENSGALP00010041494.1" } ] } }, { "isoform_ac": "A0A8V1AGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5/entry#A0A8V1AGM1-1", "sequence": { "sequence": "MPWLENDQMWISWSHNTNVNVTNEFLVKLRDHKITLKLWDTKDQVFSEARLTKPDVSSIEDEEAVDGVKHTVLQQRRLFEGSQPAPSCTKIREAKESKAQKESSALPIKEETDQSGLGTSSCNVLHPPKTDDSTVRFEGNAQLLKQKAVAAPSHNAASEETGETASNVGIPMCQTDKTATFNGRRDSGAKKGMDTTRANIASLQLDLMPLLSGENSVISRLEENSPILLDAYVSFTVETPLLSERQIRELNPLVIKICSATSLPNTPVPIEVLQKLCVPTYCKYKFHNFPAHQTHGQIHGTHVYFKDVNVFLTGRMKPGELQRCLRGPPLEIEVHDRDRKIEDNKKEPCLFGEDHTDENLGELRPLPCQSAICNSFAEDEVWHPHGVAKVSLSDLLLGKKYLTVSAPIRSCSTPNTAAFNKKNKRKKIGKKHPQILLPMGHYLQSDSLLKLRVEIAVPLRMHAEIDDAQVTDCPYSCIVYIFDYSNSFLLHDLVEEITEINAKALQLDCYPPHLIRTSLATLKLKSTLEKVSELDVVTGFHLLDGATHLFVLEGLKDKAIKRLWDRHFERTYRHEDGQLEILYNSQLSFSQRLYTNLEAIFYRFHLCKPLFTILKQPLLYVRGAVPWACFQALSRLSYLCHSKRLRDVIQGDLLPSAEMITALSREYGVPLADEDLFTQKPPLLLFSSDYTPPGNVSREKKARYSSLDHYNERYVLWKKEIADKKSFERNHIRANIDAVRQLKGKMKRLKFETFRIFPADGKSVYNYSSQRLNSAELAKKHLRQEMAKDPKTRFSYCHEYLSATFDPVDVVAACKESFAKSKSMWLSPDGFVFAGFKSSIESNLHPRMPDEARVEELREKWQENALFANMAPVLPRGRWSWDKRHVDFELYKKPPELPMATAALTDASHFVQNACDDTKLKVHWCSAAAELCAREPGATSELQQLQGLLKDEPLKFPLRKPGLILKPNPALSVLDSQNSSDVLPGKKSVCSGFVPGLQDHHSRKWNKNIIPWHNREHKKIEKLEGADFNLLGSKQSVYKSDQAASKHATTYAQQEDPLQNDILDTGNSVNTRECVTGQN", "length": 1079, "header": "tr|A0A8V1AGM1-1|A0A8V1AIG5_CHICK Computationally mapped isoform of Cilia and flagella associated protein 92 (putative) OS=Gallus gallus OX=9031 GN=KIAA1257 PE=4 SV=1 CANONICAL=A0A8V1AIG5-1" }, "locus": { "chromosome": "12", "start_pos": 5403720, "end_pos": 5383296, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067761.1", "url": "https://www.ensembl.org/id/ENSGALT00010067761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041504.1", "url": "https://www.ensembl.org/id/ENSGALP00010041504.1" } ] } }, { "isoform_ac": "A0A8V1AIG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5/entry#A0A8V1AIG5-1", "sequence": { "sequence": "MTTNPPDRRGKGAPADELKTKRCYCIECFLLPDDLVPRKMDLVVVGMVAKLFAESDSKTIMPWLENDQMWISWSHNTNVNVTNEFLVKLRDHKITLKLWDTKDQVFSEARLTKPDVSSIEDEEAVDGVKHTVLQQRRLFEGSQPAPSCTKIREAKESKAQKESSALPIKEETDQSGLGTSSCNVLHPPKTDDSTVRFEGNAQLLKQKAVAAPSHNAASEETGETASNVGIPMCQTDKTATFNGENSVISRLEENSPILLDAYVSFTVETPLLSERQIRELNPLVIKICSATSLPNTPVPIEVLQKLCVPTYCKYKFHNFPAHQTHGQIHGTHVYFKDVNVFLTGRMKPGELQRCLRGPPLEIEVHDRDRKIEDNKKEPCLFGEDHTDENLGELRPLPCQSAICNSFAEDEVWHPHGVAKVSLSDLLLGKKYLTVSAPIRSCSTPNTAAFNKKNKRKKIGKKHPQILLPMGHYLQSDSLLKLRVEIAVPLRMHAEIDDAQVTDCPYSCIVYIFDYSNSFLLHDLVEEITEINAKALQLDCYPPHLIRTSLATLKLKSTLEKVSELDVVTGFHLLDGATHLFVLEGLKDKAIKRLWDRHFERTYRHEDGQLEILYNSQLSFSQRLYTNLEAIFYRFHLCKPLFTILKQPLLYVRGAVPWACFQALSRLSYLCHSKRLRDVIQGDLLPSAEMITALSREYGVPLADEDLFTQKPPLLLFSSDYTPPGNVSREKKARYSSLDHYNERYVLWKKEIADKKSFERNHIRANIDAVRQLKGKMKRLKFETFRIFPADGKSVYNYSSQRLNSAELAKKHLRQEMAKDPKTRFSYCHEYLSATFDPVDVVAACKESFAKSKSMWLSPDGFVFAGFKSSIESNLHPRMPDEARVEELREKWQENALFANMAPVLPRGRWSWDKRHVDFELYKKPPELPMATAALTAAELCAREPGATSELQQLQGLLKDEPLKFPLRKPGLILKPNPALSVLDSQNSSDVLPGKKSVCSGFVPGLQDHHSRKWNKNIIPWHNREHKKIEKLEGADFNLLGSKQSVYKSDQAASKHATTYAQQEDPLQNDILDTGNSVNTRECVTGQN", "length": 1087, "header": "tr|A0A8V1AIG5-1|A0A8V1AIG5_CHICK Isoform 1 of Cilia and flagella associated protein 92 (putative) OS=Gallus gallus OX=9031 GN=KIAA1257 PE=4 SV=1 CANONICAL=A0A8V1AIG5-1" }, "locus": { "chromosome": "12", "start_pos": 5403720, "end_pos": 5381317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067754.1", "url": "https://www.ensembl.org/id/ENSGALT00010067754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041497.1", "url": "https://www.ensembl.org/id/ENSGALP00010041497.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIG5" }, { "id": "PF15084", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15084" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4550", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 114, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 725, "end_pos": 727 }, { "start_pos": 796, "end_pos": 798 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 986, "end_pos": 988 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL09-1", "uniprot_ac": "A0A8V1AL09", "uniprot_id": "A0A8V1AL09_CHICK", "mass": { "chemical_mass": 114762.0, "monoisotopic_mass": 114762.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM37", "type": "recommended", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM37", "type": "recommended", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase TRIM37", "type": "synonym", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#names_and_taxonomy" } ] }, { "name": "Tripartite motif-containing protein 37", "type": "synonym", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM37", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09", "locus": { "chromosome": "19", "start_pos": 7635751, "end_pos": 7671795, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029235", "url": "https://www.ensembl.org/id/ENSGALG00010029235" } ] } } ], "crossref": [ { "id": "A0A8V1AL09", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL09", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03773", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03773", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16619", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16619", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19779", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19779", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417628", "url": "https://www.ncbi.nlm.nih.gov/gene/417628", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417628", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417628", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABI9", "url": "https://www.orthodb.org/?gene=A0A8V1ABI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABJ2", "url": "https://www.orthodb.org/?gene=A0A8V1ABJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGT5", "url": "https://www.orthodb.org/?gene=A0A8V1AGT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGT9", "url": "https://www.orthodb.org/?gene=A0A8V1AGT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIX0", "url": "https://www.orthodb.org/?gene=A0A8V1AIX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIX4", "url": "https://www.orthodb.org/?gene=A0A8V1AIX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL04", "url": "https://www.orthodb.org/?gene=A0A8V1AL04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL09", "url": "https://www.orthodb.org/?gene=A0A8V1AL09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMP5", "url": "https://www.orthodb.org/?gene=A0A8V1AMP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36754", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36754", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36754:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36754:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22486", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22486", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTRCISGGFTFLQFQGLFPPSICSQDPAIQLSLFYFGNVYFGSLKGKHKGYSYISQH", "length": 1037, "header": "tr|A0A8V1AL09-1|A0A8V1AL09_CHICK Isoform 1 of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1ABI9-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTR", "length": 942, "header": "tr|A0A8V1ABI9-1|A0A8V1ABI9_CHICK Computationally mapped isoform of Tripartite motif containing 37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=4 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7651566, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070657.1", "url": "https://www.ensembl.org/id/ENSGALT00010070657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043348.1", "url": "https://www.ensembl.org/id/ENSGALP00010043348.1" } ] } }, { "isoform_ac": "A0A8V1ABJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1ABJ2-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTSFSRCLLLMQLETSSFHSNQQG", "length": 1004, "header": "tr|A0A8V1ABJ2-1|A0A8V1ABJ2_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7636841, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070662.1", "url": "https://www.ensembl.org/id/ENSGALT00010070662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043353.1", "url": "https://www.ensembl.org/id/ENSGALP00010043353.1" } ] } }, { "isoform_ac": "A0A8V1AGT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1AGT5-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTSRQIGVCTACHRGMCG", "length": 998, "header": "tr|A0A8V1AGT5-1|A0A8V1AL09_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7651803, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070654.1", "url": "https://www.ensembl.org/id/ENSGALT00010070654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043345.1", "url": "https://www.ensembl.org/id/ENSGALP00010043345.1" } ] } }, { "isoform_ac": "A0A8V1AGT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1AGT9-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTSFILGMSILGV", "length": 993, "header": "tr|A0A8V1AGT9-1|A0A8V1AL09_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7645849, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070659.1", "url": "https://www.ensembl.org/id/ENSGALT00010070659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043350.1", "url": "https://www.ensembl.org/id/ENSGALP00010043350.1" } ] } }, { "isoform_ac": "A0A8V1AIX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1AIX0-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTR", "length": 983, "header": "tr|A0A8V1AIX0-1|A0A8V1AIX0_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7651566, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070656.1", "url": "https://www.ensembl.org/id/ENSGALT00010070656.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043347.1", "url": "https://www.ensembl.org/id/ENSGALP00010043347.1" } ] } }, { "isoform_ac": "A0A8V1AIX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1AIX4-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTRLKSILKSGMQTCLSSIFLRIFLMAWMDVS", "length": 1012, "header": "tr|A0A8V1AIX4-1|A0A8V1AIX4_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7641407, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070661.1", "url": "https://www.ensembl.org/id/ENSGALT00010070661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043352.1", "url": "https://www.ensembl.org/id/ENSGALP00010043352.1" } ] } }, { "isoform_ac": "A0A8V1AL04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1AL04-1", "sequence": { "sequence": "MDEQSVERWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTR", "length": 949, "header": "tr|A0A8V1AL04-1|A0A8V1AL04_CHICK Computationally mapped isoform of Tripartite motif containing 37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=4 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7651566, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070655.1", "url": "https://www.ensembl.org/id/ENSGALT00010070655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043346.1", "url": "https://www.ensembl.org/id/ENSGALP00010043346.1" } ] } }, { "isoform_ac": "A0A8V1AL09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1AL09-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTRCISGGFTFLQFQGLFPPSICSQDPAIQLSLFYFGNVYFGSLKGKHKGYSYISQH", "length": 1037, "header": "tr|A0A8V1AL09-1|A0A8V1AL09_CHICK Isoform 1 of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7645808, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070660.1", "url": "https://www.ensembl.org/id/ENSGALT00010070660.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043351.1", "url": "https://www.ensembl.org/id/ENSGALP00010043351.1" } ] } }, { "isoform_ac": "A0A8V1AMP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09/entry#A0A8V1AMP5-1", "sequence": { "sequence": "MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCNLTKHEENEKDKCENHHEKLSVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISLVQEVERNVEAVRSAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPAYDSTTFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAGLPETSKYEYRVEMVHQSTNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNRQNDTVILRFQVRSPTFFQKCRDQHWYIAQLEAAQTSYIQQINNLKERLAIELSRTQKSRGISPPDTHLSPQNDDGPETRSKKSGPSTEALLESVAAPGLVRDNKDEDEEKIQHEDFNHELSDGDLDVDLAGEDEVNHLDGSSSSASSTATSNTEENDIDEETMSGENDVEYSNNMELEEGDLMEDAAAAAAPGASGTSHGYTSASGRPSRRGGSALGSAASSSLLDIDPLILIHLLDLKDRNGMENLWGLQPRPPASILQSRASSYSLKDRDLRRHQAMWRVPPDLKMLKRLKTQMAEVRSKMSDVKNQLSEVRSSNAGSCDGQPNFFSIEQGALAACGTDGCSKLQEIGMELLTKSSVTSCYIRNSASKKRDSPKPIRSGAAGSLSLRRAMDCGDNNLRLKGDGQTCEGGAGSSKSSSRHHCPRPLASSNASEALPKPEERPCEGSDSDVGVSGLNGLAAVEKTRKAGALGSNPKGYRTEGTQSGGLEDSSETGELQGVLPEGASAGPEEGGSCQKHVLHLLPGMSSDSDIECDTENEEQEDATSTSEGFNHAFSVQSSSEASERCSAFPGGDQVGPDDLSFVNGEDTTRPLPG", "length": 987, "header": "tr|A0A8V1AMP5-1|A0A8V1AMP5_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase TRIM37 OS=Gallus gallus OX=9031 GN=TRIM37 PE=3 SV=1 CANONICAL=A0A8V1AL09-1" }, "locus": { "chromosome": "19", "start_pos": 7671614, "end_pos": 7649197, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070658.1", "url": "https://www.ensembl.org/id/ENSGALT00010070658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043349.1", "url": "https://www.ensembl.org/id/ENSGALP00010043349.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417628", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417628", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "ESC/E(Z) complex", "id": "GO:0035098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "aggresome", "id": "GO:0016235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "tumor necrosis factor receptor binding", "id": "GO:0005164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005164", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "histone H2AK119 ubiquitin ligase activity", "id": "GO:0140862", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140862", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "negative regulation of centriole replication", "id": "GO:0046600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046600", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" }, { "name": "aggresome assembly", "id": "GO:0070842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V1AGU6/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AGU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ25", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ25#function" }, { "database": "UniProtKB", "id": "ARBA00054559", "url": "https://www.uniprot.org/uniprotkb/ARBA00054559#function" }, { "database": "UniProtKB", "id": "A0A8V1AKU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU3#function" }, { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUGP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6", "locus": { "chromosome": "28", "start_pos": 3981909, "end_pos": 3963033, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028523", "url": "https://www.ensembl.org/id/ENSGALG00010028523" } ] } } ], "crossref": [ { "id": "A0A8V1AGU6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "428349", "url": "https://www.ncbi.nlm.nih.gov/gene/428349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428349", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428349", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AGU6", "url": "https://www.orthodb.org/?gene=A0A8V1AGU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ25", "url": "https://www.orthodb.org/?gene=A0A8V1AJ25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKU3", "url": "https://www.orthodb.org/?gene=A0A8V1AKU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23340:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23340:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ25", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRASSGTTAPRGLCGSAVAHRSARAQRGAWWDSSSKMDHHHHHHHHRDAPGKASRWFGVAQSKSAKTTANILQQEELIAQKKREIEARLEQQARQSALSLQQLPLLGEDDGTENEASVSNKFVNDGSFLQQFLKLQKEKSSTEPPPSSTNNSANASAPNVGKKPVLFGKRPGQVLSSMLQQAKNYSHSKQTPVVNRLSVFQSPDEDEEEDYEQWLEIKVLPPEDAETRQVVEKLARFVAEGGPELEKVAMEDYKDNPAFSFLHDKNSREFLYYRKKVAEIRKENQSSQASSSQKVSPPEDEETKNFAEKLARFIADGGPEVEAIALQNNRENHAFRFLYEPNSKGYKYYRQKLEEFRKAKTSAASAPVPAEPSLKRKTSPEASPSPLCLPSLPLPAPTPLPLPLPVPVPSPLPLPVPTPLPVPLPVPTPLPVPLPVPPPLPSPSPSSSSTPPNQTATTTAATTAAAAAGTTKKKRKSRWGPEEDKVELPLPQLIQQLDSPSPLSVQDLKGLGYEKGKPVGLVGVTELSEAQKKQLKEQQEMQQMYDMIMKHKQAMQEMQMMWEKAIQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQLTQMGRGKHFIGDFLPPDELEKFMETFKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSDGQGIKNPVSKGTTAVDGAGFGIDRPAELTKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY", "length": 735, "header": "tr|A0A8V1AGU6-1|A0A8V1AGU6_CHICK Isoform 1 of SURP and G-patch domain-containing protein 1 OS=Gallus gallus OX=9031 GN=SUGP1 PE=1 SV=1 CANONICAL=A0A8V1AGU6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6/entry#A0A8V1AGU6-1", "sequence": { "sequence": "MRASSGTTAPRGLCGSAVAHRSARAQRGAWWDSSSKMDHHHHHHHHRDAPGKASRWFGVAQSKSAKTTANILQQEELIAQKKREIEARLEQQARQSALSLQQLPLLGEDDGTENEASVSNKFVNDGSFLQQFLKLQKEKSSTEPPPSSTNNSANASAPNVGKKPVLFGKRPGQVLSSMLQQAKNYSHSKQTPVVNRLSVFQSPDEDEEEDYEQWLEIKVLPPEDAETRQVVEKLARFVAEGGPELEKVAMEDYKDNPAFSFLHDKNSREFLYYRKKVAEIRKENQSSQASSSQKVSPPEDEETKNFAEKLARFIADGGPEVEAIALQNNRENHAFRFLYEPNSKGYKYYRQKLEEFRKAKTSAASAPVPAEPSLKRKTSPEASPSPLCLPSLPLPAPTPLPLPLPVPVPSPLPLPVPTPLPVPLPVPTPLPVPLPVPPPLPSPSPSSSSTPPNQTATTTAATTAAAAAGTTKKKRKSRWGPEEDKVELPLPQLIQQLDSPSPLSVQDLKGLGYEKGKPVGLVGVTELSEAQKKQLKEQQEMQQMYDMIMKHKQAMQEMQMMWEKAIQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQLTQMGRGKHFIGDFLPPDELEKFMETFKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSDGQGIKNPVSKGTTAVDGAGFGIDRPAELTKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY", "length": 735, "header": "tr|A0A8V1AGU6-1|A0A8V1AGU6_CHICK Isoform 1 of SURP and G-patch domain-containing protein 1 OS=Gallus gallus OX=9031 GN=SUGP1 PE=1 SV=1 CANONICAL=A0A8V1AGU6-1" }, "locus": { "chromosome": "28", "start_pos": 3981061, "end_pos": 3963139, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069081.1", "url": "https://www.ensembl.org/id/ENSGALT00010069081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042523.1", "url": "https://www.ensembl.org/id/ENSGALP00010042523.1" } ] } }, { "isoform_ac": "A0A8V1AJ25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6/entry#A0A8V1AJ25-1", "sequence": { "sequence": "MDHHHHHHHHRDAPGKASRWFGVAQSKSAKTTANILQQEELIAQKKREIEARLEQQARQSALSLQQLPLLGEDDGTENEASVSNKFVNDGSFLQQFLKLQKEKSSTEPPPSSTNNSANASAPNVGKKPVLFGKRPGQVLSSMLQQAKNYSHSKQTPVVNRLSVFQSPDEDEEEDYEQWLEIKVLPPEDAETRQVVEKLARFVAEGGPELEKVAMEDYKDNPAFSFLHDKNSREFLYYRKKVAEIRKENQSSQASSSQKVSPPEDEETKNFAEKLARFIADGGPEVEAIALQNNRENHAFRFLYEPNSKGYKYYRQKLEEFRKAKTSAASAPVPAEPSLKRKTSPEASPSPLCLPSLPLPAPTPLPLPLPTATTTAATTAAAAAGTTKKKRKSRWGPEEDKVELPLPQLIQQLDSPSPLSVQDLKGLGYEKGKPVGLVGVTELSEAQKKQLKEQQEMQQMYDMIMKHKQAMQEMQMMWEKAIQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQLTQMGRGKHFIGDFLPPDELEKFMETFKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSDGQGIKNPVSKGTTAVDGAGFGIDRPAELTKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY", "length": 650, "header": "tr|A0A8V1AJ25-1|A0A8V1AJ25_CHICK Computationally mapped isoform of SURP and G-patch domain-containing protein 1 OS=Gallus gallus OX=9031 GN=SUGP1 PE=1 SV=1 CANONICAL=A0A8V1AGU6-1" }, "locus": { "chromosome": "28", "start_pos": 3981061, "end_pos": 3964225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069080.1", "url": "https://www.ensembl.org/id/ENSGALT00010069080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042522.1", "url": "https://www.ensembl.org/id/ENSGALP00010042522.1" } ] } }, { "isoform_ac": "A0A8V1AKU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6/entry#A0A8V1AKU3-1", "sequence": { "sequence": "MDHHHHHHHHRDAPGKASRWFGVAQSKSAKTTANILQQEELIAQKKREIEARLEQQARQSALSLQQLPLLGEDDGTENEASVSNKFVNDGSFLQQFLKLQKEKSSTEPPPSSTNNSANASAPNVGKKPVLFGKRPGQVLSSMLQQAKNYSHSKQTPVVNRLSVFQSPDEDEEEDYEQWLEIKVLPPEDAETRQVVEKLARFVAEGGPELEKVAMEDYKDNPAFSFLHDKNSREFLYYRKKVAEIRKENQSSQASSSQKVSPPEDEETKNFAEKLARFIADGGPEVEAIALQNNRENHAFRFLYEPNSKGYKYYRQKLEEFRKAKTSAASAPVPAEPSLKRKTSPEASPSPLCLPSLPLPAPTPLPLPLPVPVPSPLPLPVPTPLPVPLPVPTPLPVPLPVPPPLPSPSPSSSSTPPNQTATTTAATTAAAAAGTTKKKRKSRWGPEEDKVELPLPQLIQQLDSPSPLSVQDLKGLGYEKGKPVGLVGVTELSEAQKKQLKEQQEMQQMYDMIMKHKQAMQEMQMMWEKAIQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQLTQMGRGKHFIGDFLPPDELEKFMETFKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSDGQGIKNPVSKGTTAVDGAGFGIDRPAELTKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY", "length": 699, "header": "tr|A0A8V1AKU3-1|A0A8V1AKU3_CHICK Computationally mapped isoform of SURP and G-patch domain-containing protein 1 OS=Gallus gallus OX=9031 GN=SUGP1 PE=1 SV=1 CANONICAL=A0A8V1AGU6-1" }, "locus": { "chromosome": "28", "start_pos": 3981061, "end_pos": 3964225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069078.1", "url": "https://www.ensembl.org/id/ENSGALT00010069078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042520.1", "url": "https://www.ensembl.org/id/ENSGALP00010042520.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 398, "start_aa": "Thr", "end_pos": 398, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr398", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 450, "start_aa": "Thr", "end_pos": 450, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr450", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428349", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428349", "resource": "KEGG Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 652, "end_pos": 699, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AGU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU6" }, { "id": "PS50128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SURP motif", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 272, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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CANONICAL=A0A8V1AGU7-1" }, "locus": { "chromosome": "17", "start_pos": 1089061, "end_pos": 1087506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067838.1", "url": "https://www.ensembl.org/id/ENSGALT00010067838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041581.1", "url": "https://www.ensembl.org/id/ENSGALP00010041581.1" } ] } }, { "isoform_ac": "A0A8V1AGU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU7/entry#A0A8V1AGU7-1", "sequence": { "sequence": "RPSRGRARGGSSRGSGPDRPEALGKAPTAPPWQRRKGRCERRGRRCGNGRGCDGAPRAAAGGGQRGRQTPGAAAVRGVSGPRLHEGHRHLPGGYGHGGTRREGLPRYRLPPGPDGAVAGTARLAVRAGSGAAFAVQKLVNRRLPYALQWNLLLSVAAGSLASYTVTRAETQKCSDFWIYLETGMSPRERSVADGVPQPADNLLSPEDAESVSPPVRRNKYGDVVE", "length": 225, "header": "tr|A0A8V1AGU7-1|A0A8V1AGU7_CHICK Isoform 1 of Transmembrane protein 141 OS=Gallus gallus OX=9031 GN=TMEM141 PE=1 SV=1 CANONICAL=A0A8V1AGU7-1" }, "locus": { "chromosome": "17", "start_pos": 1089061, "end_pos": 1087506, "strand": 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This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015153862.2. 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"https://www.orthodb.org/?gene=A0A8V1AKX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21229:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21229:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06814", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06814", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9B0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ44", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAGVWESICQCLSMPENTSPIELLCKRNPAPGPAIHEDIDLHLLEEAQLLCFGMHLVLANLVGLQ", "length": 588, "header": "tr|A0A8V1AJ53-1|A0A8V1AJ53_CHICK Isoform 1 of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1A9B0-1", "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAVVTTSGVMEGMKKVKKVVNGSAEPRGEWESTA", "length": 529, "header": "tr|A0A8V1A9B0-1|A0A8V1A9B0_CHICK Computationally mapped isoform of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6458640, "end_pos": 6430078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069107.1", "url": "https://www.ensembl.org/id/ENSGALT00010069107.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042549.1", "url": "https://www.ensembl.org/id/ENSGALP00010042549.1" } ] } }, { "isoform_ac": "A0A8V1AEH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1AEH3-1", "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAVVTTSGVMEGMKKVKKVVNGSAEPRGEWESTA", "length": 538, "header": "tr|A0A8V1AEH3-1|A0A8V1AEH3_CHICK Computationally mapped isoform of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6458640, "end_pos": 6430078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069110.1", "url": "https://www.ensembl.org/id/ENSGALT00010069110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042551.1", "url": "https://www.ensembl.org/id/ENSGALP00010042551.1" } ] } }, { "isoform_ac": "A0A8V1AGX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1AGX2-1", "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLEGTLKMFCFHWQDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAVVTTSGVMEGMKKVKKVVNGSAEPRGEWESTA", "length": 569, "header": "tr|A0A8V1AGX2-1|A0A8V1AJ53_CHICK Computationally mapped isoform of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6458640, "end_pos": 6430078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069111.1", "url": "https://www.ensembl.org/id/ENSGALT00010069111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042553.1", "url": "https://www.ensembl.org/id/ENSGALP00010042553.1" } ] } }, { "isoform_ac": "A0A8V1AJ44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1AJ44-1", "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAVLNIANHCGNADLPLPVPWDLEFLPVS", "length": 552, "header": "tr|A0A8V1AJ44-1|A0A8V1AJ44_CHICK Computationally mapped isoform of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6455369, "end_pos": 6430078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069105.1", "url": "https://www.ensembl.org/id/ENSGALT00010069105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042547.1", "url": "https://www.ensembl.org/id/ENSGALP00010042547.1" } ] } }, { "isoform_ac": "A0A8V1AJ53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1AJ53-1", "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAGVWESICQCLSMPENTSPIELLCKRNPAPGPAIHEDIDLHLLEEAQLLCFGMHLVLANLVGLQ", "length": 588, "header": "tr|A0A8V1AJ53-1|A0A8V1AJ53_CHICK Isoform 1 of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6466405, "end_pos": 6430078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069115.1", "url": "https://www.ensembl.org/id/ENSGALT00010069115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042557.1", "url": "https://www.ensembl.org/id/ENSGALP00010042557.1" } ] } }, { "isoform_ac": "A0A8V1AKW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1AKW3-1", "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAC", "length": 526, "header": "tr|A0A8V1AKW3-1|A0A8V1AKW3_CHICK Computationally mapped isoform of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6453561, "end_pos": 6430078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069103.1", "url": "https://www.ensembl.org/id/ENSGALT00010069103.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042545.1", "url": "https://www.ensembl.org/id/ENSGALP00010042545.1" } ] } }, { "isoform_ac": "A0A8V1AKW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1AKW8-1", "sequence": { "sequence": "MDHCLKHDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLEGTLKMFCFHWQDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWSIRHLQEASATDGKAAINLAKLKLFRHYYVMIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAVVTTSGVMEGMKKVKKVVNGSAEPRGEWESTA", "length": 541, "header": "tr|A0A8V1AKW8-1|A0A8V1AKW8_CHICK Computationally mapped isoform of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6458640, "end_pos": 6433012, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069108.1", "url": "https://www.ensembl.org/id/ENSGALT00010069108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042550.1", "url": "https://www.ensembl.org/id/ENSGALP00010042550.1" } ] } }, { "isoform_ac": "A0A8V1AKX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53/entry#A0A8V1AKX3-1", "sequence": { "sequence": "MAARGLSAALAVAVLGLALLCAGPVGARVHHLTLKDDVRQKVHLNTFGFFKNGFMKVNVSNLSLKPPVNADDKSSSSVGFSLDRTRNDGFSTYLDEEVDYCILNKKPEQGVSVVILLLDFKNDVVKVQFSAEASHLLPKISFVSDENATALITKPPKSSEDKSDSVKSPTETNKNTAGKDTKSKRSTTSSQSIVEQKHPVHNDRGTISFQFFFNISSDDQEGLYSLYFHKCIGSEGKTRDQQLFSLDIEITEKNPESYLSAGEIPLPKLYISMALFFFLSGTVWIHILRKRRNDVFKIHWLMAALPFTKSLSLVFHAIDYHYISSQGFPIEGWAVVYYITHLFKGALLFITIALIGTGWAFIKHILSDKDKKIFMIVIPLQVLANVAYIIIESTEEGTTEYGLWKEILFLVDLLCCGAILFPVVWFSQDDAIVLAHRLCVSFPQIVCYIYFTQIIAILIKIAVPFQWKWLYQLLNEMATLVFFVLTGYKFRPASDNPYLQLSQDDEDDLEMEAVVTTSGVMEGMKKVKKVVNGSAEPRGEWESTA", "length": 545, "header": "tr|A0A8V1AKX3-1|A0A8V1AKX3_CHICK Computationally mapped isoform of G protein-coupled receptor 107 OS=Gallus gallus OX=9031 GN=GPR107 PE=1 SV=1 CANONICAL=A0A8V1AJ53-1" }, "locus": { "chromosome": "17", "start_pos": 6458640, "end_pos": 6430078, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069113.1", "url": "https://www.ensembl.org/id/ENSGALT00010069113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042555.1", "url": "https://www.ensembl.org/id/ENSGALP00010042555.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "clathrin heavy chain binding", "id": "GO:0032050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" }, { "id": "PF21904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAND6/7 N-terminal", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 106, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ53" }, { "id": "PF06814", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06814" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GOST seven transmembrane", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 509, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF28521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MAKRKQRRRKPRGRTKPGRRREAGAAASQPQLSAFHTTPPSAQRRTAAPRGRGDRSAAIRPGPAHLPPDAAAAAARASLCSLPLHGVKHVVKPLAAVAALLYCWCHSAVAQSFTAVKEMIFPSQVYLKELNAFKEQLEKLEMEFSRLQGILQKSGIMTLSSESSHCQRCSKTVLGAPVEVQPDPPPSVPGPPAVQLQPTAVPPPLPPPPPPPPPPLPPPKLPAAPLLLKRGNGSKALLEPSVKKDAPMHITLKDLLNVKLRKTDSSLRTDKAGSPARTRRALITVSDLQSVNLRSKSKPSAHVTSSLNTPPKNQLDLRKHLKKVNIQRSPGGTPLNKENTECGTGLTPIMTQALRRKFQASLDVCLETTSWFLNPCGFIWIFVLHCSDISAQSIILTPTCSVPTNKGVCFITPILMVRKLQNVSGVVPLPAGDLTWLRTKMAFFITIPVLSAPSLSSEFYPGEQNLRIHHNFYLQDWPRLFSFTKHQLRVTLYLSSNEYQAPVPSSDPALVLTDGTSEESLTGPAERCQQL", "length": 531, "header": "tr|A0A8V1AGX9-1|A0A8V1AGX9_CHICK Isoform 1 of Proline rich 11 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGX9-1" }, "locus": { "chromosome": "19", "start_pos": 7683679, "end_pos": 7680500, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070699.1", "url": "https://www.ensembl.org/id/ENSGALT00010070699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043390.1", "url": "https://www.ensembl.org/id/ENSGALP00010043390.1" } ] } }, { "isoform_ac": "A0A8V1AL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX9/entry#A0A8V1AL47-1", "sequence": { "sequence": "MGNASLTAAMAKRKQRRRKPRGRTKPGRRREAGAAASQPQLSAFHTTPPSAQRRTAAPRGRGDRSAAIRPGPAHLPPDAAAAAARASLCSLPLHGVKHVVKPLAAVAALLYCWCHSAVAQSFTAVKEMIFPSQVYLKELNAFKEQLEKLEMEFSRLQGILQKSGIMTLSSESSHCQRCSKTVLGAPVEVQPDPPPSVPGPPAVQLQPTAVPPPLPPPPPPPPPPLPPPKLPAAPLLLKRGNGSKALLEPSVKKDAPMHITLKDLLNVKLRKTDSSLRTDKAGSPARTRRALITVSDLQSVNLRSKSKPSAHVTSSLNTPPKNQLDLRKHLKKVNIQRSPGGTPLNKENTECGTGLTPIMTQALRRKFQMAHPKSPSPARLSAANSFDEHK", "length": 390, "header": "tr|A0A8V1AL47-1|A0A8V1AL47_CHICK Computationally mapped isoform of Proline rich 11 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AGX9-1" }, "locus": { "chromosome": "19", "start_pos": 7683692, "end_pos": 7680473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070700.1", "url": "https://www.ensembl.org/id/ENSGALT00010070700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043391.1", "url": "https://www.ensembl.org/id/ENSGALP00010043391.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX9" }, { "id": "PF28521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PRR11 first helical", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 120, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AGX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGX9" }, { "id": "PF28520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PRR11 second helical", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 153, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 422, "end_pos": 424 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGY0-1", "uniprot_ac": "A0A8V1AGY0", "uniprot_id": "A0A8V1AGY0_CHICK", "mass": { "chemical_mass": 110579.0, "monoisotopic_mass": 110579.0 }, "refseq": { "ac": "XP_004935048", "name": "uncharacterized protein C6orf132 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935048" }, "gene_names": [ { "name": "C6orf132", "type": "recommended", "evidence": [ { "id": "A0A8V1AGY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0" } ] }, { "name": "C6orf132", "type": "synonym", "evidence": [ { "id": "XP_004935048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935048" } ] } ], "protein_names": [ { "name": "Chromosome 6 open reading frame 132", "type": "synonym", "evidence": [ { "id": "A0A8V1AGY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C6orf132 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004935048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935048" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004935048.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935048" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C6orf132", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0", "locus": { "chromosome": "26", "start_pos": 3249627, "end_pos": 3230451, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027557", "url": "https://www.ensembl.org/id/ENSGALG00010027557" } ] } } ], "crossref": [ { "id": "A0A8V1AGY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750708", "url": "https://www.ncbi.nlm.nih.gov/gene/101750708", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:101750708", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750708", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GREEVPC", "url": "https://omabrowser.org/oma/group/GREEVPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4M7", "url": "https://www.orthodb.org/?gene=A0A8V1A4M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGY0", "url": "https://www.orthodb.org/?gene=A0A8V1AGY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35077", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35077", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35077:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35077:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004935048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935048", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A4M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKHHSVQGTFSRLFGKKHGTAAASLFATNPPWIFSQEVTSDSAGGTGDVIEVYYGDNRFGTMTDSGTATLKPRPRVRPLLTFLPLNAQESHGVAVPTPSVPEDFEEKAALGPGSQMNGNYRMYSSVGDLRPQALEREDEDEDIPPPPSVPPPPPPTARALTPPPLAPPAPPPPEALPPLPPPEAVPPPPAVAPPPPPESTLPSPTTPAPPDFIPPAPPLSKAPVPFSNGISKWKSETVLNTRQVDDEGPLCPAETKVPAAPSAEESPQPPKQCPEPHLTFPRSFKVPPPAPARSSSIPMQESQPSRAEPFTRQPHARPPLPPCFTIRPAAKAHAGEAKERNPPLRQPFTKAAPPPLSPKPGAVLSSRSSVPSSEPKNLQPKTDTRDSPPKSEVITANDLELPPPDYPPCEDSWKDPSSLSQLQHELSALLRSPRRDERQKEGPAAPQLANGSTNHAGSHGPDGARLVGKALSSPTGEESERREGPGSSPSTMGGHPSAAQPAVESSPAVQPHSVKKIRSELEAVFSLKKERKPALGLGGEKQGPEDGGSASRSGLSPPEPGGETVLPKPAPSSLPAPAAAAVVEKTTEQEEHPAPVIPAANKAMESSTPAPSSADSSVSPPGPPQRAVEEPPAPPVPSSPISPAPQPSADIFQYKVHRAGAGEAEPACPPSSASSPPGVQGTGQEEVLIHPVTGERVERGSPMALLLAARQRAQRGRPGSEAGGPPRARPHTKLGSTASETTSSTSFYRHESKPYSFTVVPRPSAAHSKPPSFSSSSEQGRAVGEGQQPGQQRAAASRLLRGLLEQGQPKHPDPPRHTVSGEEENGEAALDYTIIPPPPEFSNEADEPDGIPQSREENHKCPSFPDCSRGSDTPRYFRWPGYGRGYGYGSSQEPSEHSRRNGDLAPPCPDYSSSAGYLSRGPSSRPLIKKRLYVSEPEHSYPRAAARGTVLPSYGSGAYNSSAGDGARRLGSAHWNGPGSTQSRRTSIDSAGKAGPYGGADTKYKGQNGDFLVAGRPAHGSSQYGGPTNTFTVRPGARQPISYTYQSGHR", "length": 1051, "header": "tr|A0A8V1AGY0-1|A0A8V1AGY0_CHICK Isoform 1 of Chromosome 6 open reading frame 132 OS=Gallus gallus OX=9031 GN=C6orf132 PE=1 SV=1 CANONICAL=A0A8V1AGY0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A4M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0/entry#A0A8V1A4M7-1", "sequence": { "sequence": "MHSLVVAAPPESSSDRRPSGKSFAALGTSRESWDVIEVYYGDNRFGTMTDSGTATLKPRPRVRPLLTFLPLNAQESHGVAVPTPSVPEDFEEKAALGPGSQMNGNYRMYSSVGDLRPQALEREDEDEDIPPPPSVPPPPPPTARALTPPPLAPPAPPPPEALPPLPPPEAVPPPPAVAPPPPPESTLPSPTTPAPPDFIPPAPPLSKAPVPFSNGISKWKSETVLNTRQVDDEGPLCPAETKVPAAPSAEESPQPPKQCPEPHLTFPRSFKVPPPAPARSSSIPMQESQPSRAEPFTRQPHARPPLPPCFTIRPAAKAHAGEAKERNPPLRQPFTKAAPPPLSPKPGAVLSSRSSVPSSEPKNLQPKTDTRDSPPKSEVITANDLELPPPDYPPCEDSWKDPSSLSQLQHELSALLRSPRRDERQKEGPAAPQLANGSTNHAGSHGPDGARLVGKALSSPTGEESERREGPGSSPSTMGGHPSAAQPAVESSPAVQPHSVKKIRSELEAVFSLKKERKPALGLGGEKQGPEDGGSASRSGLSPPEPGGETVLPKPAPSSLPAPAAAAVVEKTTEQEEHPAPVIPAANKAMESSTPAPSSADSSVSPPGPPQRAVEEPPAPPVPSSPISPAPQPSADIFQYKVHRAGAGEAEPACPPSSASSPPGVQGTGQEEVLIHPVTGERVERGSPMALLLAARQRAQRGRPGSEAGGPPRARPHTKLGSTASETTSSTSFYRHESKPYSFTVVPRPSAAHSKPPSFSSSSEQGRAVGEGQQPGQQRAAASRLLRGLLEQGQPKHPDPPRHTVSGEEENGEAALDYTIIPPPPEFSNEADEPDGIPQSREENHKCPSFPDCSRGSDTPRYFRWPGYGRGYGYGSSQEPSEHSRRNGDLAPPCPDYSSSAGYLSRGPSSRPLIKKRLYVSEPEHSYPRAAARGTVLPSYGSGAYNSSAGDGARRLGSAHWNGPGSTQSRRTSIDSAGKAGPYGGADTKYKGQNGDFLVAGRPAHGSSQYGGPTNTFTVRPGARQPISYTYQSGHR", "length": 1036, "header": "tr|A0A8V1A4M7-1|A0A8V1A4M7_CHICK Computationally mapped isoform of Chromosome 6 open reading frame 132 OS=Gallus gallus OX=9031 GN=C6orf132 PE=1 SV=1 CANONICAL=A0A8V1AGY0-1" }, "locus": { "chromosome": "26", "start_pos": 3246796, "end_pos": 3230650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066747.1", "url": "https://www.ensembl.org/id/ENSGALT00010066747.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040857.1", "url": "https://www.ensembl.org/id/ENSGALP00010040857.1" } ] } }, { "isoform_ac": "A0A8V1AGY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY0/entry#A0A8V1AGY0-1", "sequence": { "sequence": "MKKHHSVQGTFSRLFGKKHGTAAASLFATNPPWIFSQEVTSDSAGGTGDVIEVYYGDNRFGTMTDSGTATLKPRPRVRPLLTFLPLNAQESHGVAVPTPSVPEDFEEKAALGPGSQMNGNYRMYSSVGDLRPQALEREDEDEDIPPPPSVPPPPPPTARALTPPPLAPPAPPPPEALPPLPPPEAVPPPPAVAPPPPPESTLPSPTTPAPPDFIPPAPPLSKAPVPFSNGISKWKSETVLNTRQVDDEGPLCPAETKVPAAPSAEESPQPPKQCPEPHLTFPRSFKVPPPAPARSSSIPMQESQPSRAEPFTRQPHARPPLPPCFTIRPAAKAHAGEAKERNPPLRQPFTKAAPPPLSPKPGAVLSSRSSVPSSEPKNLQPKTDTRDSPPKSEVITANDLELPPPDYPPCEDSWKDPSSLSQLQHELSALLRSPRRDERQKEGPAAPQLANGSTNHAGSHGPDGARLVGKALSSPTGEESERREGPGSSPSTMGGHPSAAQPAVESSPAVQPHSVKKIRSELEAVFSLKKERKPALGLGGEKQGPEDGGSASRSGLSPPEPGGETVLPKPAPSSLPAPAAAAVVEKTTEQEEHPAPVIPAANKAMESSTPAPSSADSSVSPPGPPQRAVEEPPAPPVPSSPISPAPQPSADIFQYKVHRAGAGEAEPACPPSSASSPPGVQGTGQEEVLIHPVTGERVERGSPMALLLAARQRAQRGRPGSEAGGPPRARPHTKLGSTASETTSSTSFYRHESKPYSFTVVPRPSAAHSKPPSFSSSSEQGRAVGEGQQPGQQRAAASRLLRGLLEQGQPKHPDPPRHTVSGEEENGEAALDYTIIPPPPEFSNEADEPDGIPQSREENHKCPSFPDCSRGSDTPRYFRWPGYGRGYGYGSSQEPSEHSRRNGDLAPPCPDYSSSAGYLSRGPSSRPLIKKRLYVSEPEHSYPRAAARGTVLPSYGSGAYNSSAGDGARRLGSAHWNGPGSTQSRRTSIDSAGKAGPYGGADTKYKGQNGDFLVAGRPAHGSSQYGGPTNTFTVRPGARQPISYTYQSGHR", "length": 1051, "header": "tr|A0A8V1AGY0-1|A0A8V1AGY0_CHICK Isoform 1 of Chromosome 6 open reading frame 132 OS=Gallus gallus OX=9031 GN=C6orf132 PE=1 SV=1 CANONICAL=A0A8V1AGY0-1" }, "locus": { "chromosome": "26", "start_pos": 3246796, "end_pos": 3230964, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066750.1", "url": "https://www.ensembl.org/id/ENSGALT00010066750.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040858.1", "url": "https://www.ensembl.org/id/ENSGALP00010040858.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 98, "start_aa": "Thr", "end_pos": 98, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr98", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101750708", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750708", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LLX1-1", "protein_name": "Chromosome 23 C6orf132 homolog", "gene_name": "C23H6orf132", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKNPTVQGTFSKLFGKKHANPPATSLYATNPPWIFTQEAPEEGTRGFDGIYYGDNRFDTVSESGTATLKARPRVRPLLTFLPLDAQENHGLAVPTPCVPDSFADKQATGTSTLVNGNLRLYSSVGDLRPGHYGQDLLIPPPPPGPAPAPPLGALQPPEFSPPPPPSTAPPPPPLLESPPPPPPSTAPALPPGMGALPPPPTVSSPSTPTPPDFIPPAPPQAVQAPPLPLLPALTPPAPGSPHTMGTRLFPAGGVTKWKSEVALNGRQPEAPRSSAPRSPAEPTEALPGPESHLTFPRSFKVPPPTPVRTSSISIPEAQGTPPEDKESTKKGPIRPSLPPSFHIRSACQAYPDRAAELALPKEPGAVAPAGPRRGQPQVQSSEQAETPPPAPPLPPPAPPLPPPAPPLPPAAPPLPPAEKAAPAPAGLMKRPKSGSPAPKPKPEPPSPEETVSSEPMDWRDPSQMAKLRDQLSAYLCGSRREDRLASHRPGPTAASQEREDHKRPSLPAKEAPPSLLQKEAPPSPPEKEAPSSVPEESPCSRPKKAATSLILPPVDYLPQDAPTPSVWEIRKKLEAQLSSLAEKEARPSRGSLPPKPQPEGGRIFENRDDNSKFPKPVAKNLPPLSTTPLPNTPLQSKVTPGPATSPKATPEPATPPKATPGPATPPKATPEPATPPKATPEPATPPKATPGPATPPKATPELATPPKATPGPATPPKAVPGPATTPKATPGPATPPKATPGPATPPKAMPGPATPPKAMLGPATTPKAVPGPATTPKATSGPATPPKATPLPITSSQLIAEKNLVPAGQWEKPEHEELAVPSKPEVEGHSSETSKPPTQGALSSPAFPPKISPGREEVPCLYKPHCSQNSSSREVAVVMPTLSRGEAAGSGKPVAVKEPQELPPKAPVSSQAADELLRHPVTGEVVERGSPMALLLAAKQRAQKGRPRGAALGRSSLPGSLQGPSQPKAGSDTILYNEGQPNSFTVVPKVSKETEKVPQLTSPGQPKGLCQWELQPRRDPEDTESCSGPSWTKVKPQASAAWERPAPSSLLQGRLLPKSFSSPPSPSHKPEEDKEEEFNFEVIPPPPEFSNDPEPPAAPLQYLGRRGSPPRNNFSDLGQPANAGPPRVFSHFADPGPARGLERFSGVGGGRSLIKKRLYVGEPHRNPGPPRGGTGRSLSFPNCFGPQPGGPFAAPSGPEMRRVNSAGRGPPGGLHSRKVSLEAPRGEAKYKALGGGGGGDYGCTQATGRSPHNNTQYGSSINTFTVRPGTRHPISYAYSGAHWKATS", "length": 1288 }, "evidence": [ { "id": "A0A8V1AGY0", "url": "https://omabrowser.org/oma/group/A0A8V1AGY0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6A9H1-1", "protein_name": "Similar to human chromosome 6 open reading frame 132", "gene_name": "C9h6orf132", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKNQTMQGTFSKLFGKKHAHTSTTSLYATNPPWIFTQEAQEEGTRDFDGIYYGDNRFNTVSESGTATLKARPRVRPLLTFIPLNAQENHGLAVPTPSVPEEFADKEVRGASTLVNGNLRLYSSVGDLRPVHYDLDSSIPPPPPGPAPGPPQDTSQPPEASSPPPPPPVPPPPPPLLVEPPPPPSTAPPPPPALDTLSPSSAFSPPSTPTPPDFIPPAPPSAFQTLPPPSLPAPGPPVPVSLHTTGTRLFPTGAIIKWKSEVALNGQQPEDPRSSPPKSPAELKRSPLGPSPEPHLTFPRSPKVPPPTPVRTSSIPVQEAPGASPEEDEATQKTSAHLPLPHSISVRPASLVYPDRALEPEQPREPRPETPGSPRLRQSEPQTNGQAGAPPPAPPLPPPAPPLPRPASSLPPAAPPLPSTERAAPPSSGFPKTSKSSSPALNPKPNPPSPEDTASSEPVDWRDPRQMEKLRSELAAYLCGSRKEDRSLSHRPVPTVASKDKENKKGTSLSEEVPPSLPEKIHPRAPEKSPSSSSLPEREASSSLALPPVDYIPQDTPAPSVKQIRNELEARFASSAEKEAKPSLASLPPKPRLEGGRTFENRTENGRFHKPATKNPPQLSTAPLPATTLQSKVVHGPATPPKVTPGSATPFKPIPGQAIPPKATPGLALPLKPTSEQTTSPKNTPRQATPPKDAPGQATPPKDAPGQATPPKDPPGQATPPKDAPGQATPPKDAPGQATPPKVIPGQATPPKDAPGQATLLKDTPRLPTPLSQPMAEKDLASMRQREKPESQENSVATQLSRNGVLSPPALPPKMSTGGEEAPFLYRPHRSQNSHSRGIAVVTPTRTRGEATDSGDLVDEKELQNHPAKPLLPVQPADQVLRHPVTGEVVERGSPMALLLAARQRAQKTRPGGTAIGRSSLPGSLRDHSNQPEASSDSIFYRGSRPNSFIVVPKVPSETEDSQVASARPTGPSQWKPLQGRDTQASDPTYRPGWTKDESLAPVARERPAHSSLPYGRALPKSFSSPPSPSYKREEEEEFSFDIIPPPPEFSNDPEPPVPGLQQQGRRGSPPRNNFSDLGQSSRPSPARGFSRFPGTQYPEPGGLDRFSGSGRSLIKKRLYVGEPHRNPGTSRGSTGRSLSSPNCFGPQPGGPEMRRVNSAGRAAPGGLNARRLSLEGARGAAEVKYKAPGGGGGSGSKTGDYGFVPHKVSRSPHGNAHYGSPINTFTVRPGTRHPISYAYSGTHRKATS", "length": 1249 }, "evidence": [ { "id": "A0A8V1AGY0", "url": "https://omabrowser.org/oma/group/A0A8V1AGY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T0Z8-1", "protein_name": "Uncharacterized protein C6orf132", "gene_name": "C6orf132", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNTVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS", "length": 1188 }, "evidence": [ { "id": "A0A8V1AGY0", "url": "https://omabrowser.org/oma/group/A0A8V1AGY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91Z58-1", "protein_name": "Uncharacterized protein C6orf132 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKNQTMQGTFSKLFGKKHAHPSTTSLYATNPPWIFTHEAQEEGTRDFDGIYYGDNRFNTVSESGTATLKARPRVRPLLTFIPLNAQENHGLAVPTPSVPEDFADKEVGGTSTLVNGNLRLYSSVGDLRPACYDLDSSIPPPPPGPAPGPPQDISQPPGESPPPPPPSVPPPPPPPLLVEPPPPPSTAPPPPPPLDILSPPSTPTPPDFIPPAPPSAFLSPPPPSLPAPGPPAPVSLHTPGTHLFPPGAITKWKSEVALNGRHPEDPRTSPPKSPAELKRSPLGPSPEPHLTFPRSPKVPPPTPVRTSSIPVQEAPGASPEEEEATQKTSAPSPLPPSFNIRPASQIYPDRALEPEQPREPRPETPGSPRLRQSEPQTNGQAGAPPPAPPLPPPAPPLPPPAPSLPPAAPPLPSTELAAPPSSGFMKTSKSNSPALKPKPKPPSVEDTASSEPVDWRDPRQMEKLRSELSAYLCGTRKEDRSLSHRPGPTVALKDKENNKGTSLSEEAAPPSLPEKVHPCIPEKSPSSSSLPEREATSSLVLPPVDYIAQDTPAPSVRQIRSELEARFASSAEKEAKPSLASLPPKPRLEGGRTFENGTDNGRFHKPATKNPPQPSTTPLPTTILQPKVVPGPATSPKVTPGPATPFKPTPGQAILPKATPGLTLPLKPTPEQTTSPKNTPGKATPLKDTPGQATTPKDTPGQDTPPKDTPGQAAVLKNAPELSTPSSQLMAEKDLASVRQREKPETQEDPVATQLSTNGTLSPPALPPKMSTSGEEAPFLYRPHRSQNSHSRGVAVVTPTRARGEAPDSGDVVDEKELQNHPAKSLTPGQPADQLLRHPVTGEVVERGSPMALLLAARQRAQKTRTGGTAIGRSSLPGSLRDHSNQPEASSDSIFYRGSRPNSFIVVPKVPSETEDSHLTSARPTGPSHWKPQQGPDTQGSEPTYRHGWTKAETPAPVARERPAPSSLPQSRALPKSFSSPPSPSYKREEEEEEFSFDIIPPPPEFSNDPEPPAPGQQHQGRRGSPPRNNFSDLGQSWGPNPTPGFSRFRGTQYPESGGLDRFSGSGRSLIKKRLYVGESHRNPGMPRGSTGRSLSSPNCFGPQPGGPEMRRVNSAGRAAPGGLHARRLSLEGARGATEVKFKAPGGGGGSSSKAGDYGFVPAKGSRSPHGNTHYGSPINTFTVRPGTRHPISYAYPGTHRKATS", "length": 1206 }, "evidence": [ { "id": "A0A8V1AGY0", "url": "https://omabrowser.org/oma/group/A0A8V1AGY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 98, 207 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 451, "end_pos": 453 }, { "start_pos": 961, "end_pos": 963 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGY1-1", "uniprot_ac": "A0A8V1AGY1", "uniprot_id": "A0A8V1AGY1_CHICK", "mass": { "chemical_mass": 13676.0, "monoisotopic_mass": 13676.0 }, "refseq": {}, "gene_names": [ { "name": "LOC426913", "type": "recommended", "evidence": [ { "id": "A0A8V1AGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC426913", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "426913", "url": "https://www.ncbi.nlm.nih.gov/gene/426913", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426913", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426913", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AGY1", "url": "https://www.orthodb.org/?gene=A0A8V1AGY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GKP9", "url": "https://www.orthodb.org/?gene=R4GKP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKP9", "url": "https://www.uniprot.org/uniprotkb/R4GKP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GKP9-1", "url": "https://www.uniprot.org/uniprotkb/R4GKP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGVVGECLDLTLLGLLGIWVAKPLYVHLHPTTMSCFDLCRPCGPTPLANSCTEPCVRQCQDSRVVIQPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSEEGVPISSGGFGISGLGSRFSGRRCLPY", "length": 131, "header": "tr|A0A8V1AGY1-1|A0A8V1AGY1_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC426913 PE=3 SV=1 CANONICAL=A0A8V1AGY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1/entry#A0A8V1AGY1-1", "sequence": { "sequence": "MWGVVGECLDLTLLGLLGIWVAKPLYVHLHPTTMSCFDLCRPCGPTPLANSCTEPCVRQCQDSRVVIQPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSEEGVPISSGGFGISGLGSRFSGRRCLPY", "length": 131, "header": "tr|A0A8V1AGY1-1|A0A8V1AGY1_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC426913 PE=3 SV=1 CANONICAL=A0A8V1AGY1-1" }, "locus": { "chromosome": "25", "start_pos": 1486942, "end_pos": 1486444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069121.1", "url": "https://www.ensembl.org/id/ENSGALT00010069121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042563.1", "url": "https://www.ensembl.org/id/ENSGALP00010042563.1" } ] } }, { "isoform_ac": "R4GKP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1/entry#R4GKP9-1", "sequence": { "sequence": "MSCFDLCRPCGPTPLANSCTEPCVRQCQDSRVVIQPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSEEGVPISSGGFGISGLGSRFSGRRCLPY", "length": 98, "header": "tr|R4GKP9-1|R4GKP9_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC426913 PE=3 SV=1 CANONICAL=A0A8V1AGY1-1" }, "locus": { "chromosome": "25", "start_pos": 1486737, "end_pos": 1486444, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069122.1", "url": "https://www.ensembl.org/id/ENSGALT00010069122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042564.1", "url": "https://www.ensembl.org/id/ENSGALP00010042564.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 46, "start_aa": "Thr", "end_pos": 46, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr46", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426913", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426913", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 46 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGY3-1", "uniprot_ac": "A0A8V1AGY3", "uniprot_id": "A0A8V1AGY3_CHICK", "mass": { "chemical_mass": 144976.0, "monoisotopic_mass": 144976.0 }, "refseq": {}, "gene_names": [ { "name": "SPAG9", "type": "recommended", "evidence": [ { "id": "A0A8V1AGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ] } ], "protein_names": [ { "name": "C-Jun-amino-terminal kinase-interacting protein 4", "type": "recommended", "evidence": [ { "id": "A0A8V1AGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#names_and_taxonomy" } ] }, { "name": "JNK-associated leucine-zipper protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#names_and_taxonomy" } ] }, { "name": "Mitogen-activated protein kinase 8-interacting protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#names_and_taxonomy" } ] }, { "name": "Sperm-associated antigen 9", "type": "synonym", "evidence": [ { "id": "A0A8V1AGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex. Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMS4#function" }, { "database": "UniProtKB", "id": "ARBA00056878", "url": "https://www.uniprot.org/uniprotkb/ARBA00056878#function" }, { "database": "UniProtKB", "id": "A0A8V1AL51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL51#function" }, { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3#function" }, { "database": "UniProtKB", "id": "A0A8V1AJ10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ10#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPAG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3", "locus": { "chromosome": "18", "start_pos": 10673461, "end_pos": 10617954, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029250", "url": "https://www.ensembl.org/id/ENSGALG00010029250" } ] } } ], "crossref": [ { "id": "422095", "url": "https://www.ncbi.nlm.nih.gov/gene/422095", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032486", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032486", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422095", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422095", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABM9", "url": "https://www.orthodb.org/?gene=A0A8V1ABM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGY3", "url": "https://www.orthodb.org/?gene=A0A8V1AGY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ06", "url": "https://www.orthodb.org/?gene=A0A8V1AJ06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ10", "url": "https://www.orthodb.org/?gene=A0A8V1AJ10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL51", "url": "https://www.orthodb.org/?gene=A0A8V1AL51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMS4", "url": "https://www.orthodb.org/?gene=A0A8V1AMS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13886", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13886", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13886:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13886:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16471", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16471", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-525793", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-525793", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ06", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL51", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELADGVVYQEDPGGPGPAMMSERVSGLAGSIYREFERLIGRYDEEVVAELMPLVVAVLENLDSVCAHSQETSVELELLRDDNEQLLTQYEREKALRKQAEEKFIEFEDSQEQEKKDLQTRVEALESQTRQLELKAKNYADQISRLEEREAELKKEYNALHSRHTEMIHNYMEHLERTKLHQLTGGDQLESTTHSRIRKERPISLGIFPLPPGDALLTPEAQREAGETPGSEHWKFHELSQPRSHTSLKDELSDVSQAGSKTTTPASTAASDVPALPAETPQKEDAEGFAKGTDMQNEKPDVSKNIEVQVAQETRNVSTGVQNTGGNENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKQKLEEKNKELEEELKKARAEAEEARQKAKEDDDSDVPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTAKKPEPPVNVKYNAPTSHITPSVKKRSSTLSQLPSDKSKAFEFLSDETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGGQGDNKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYNDVAGTDADGNKQRTGSQSSLDRLDQELKDQQKELKHQEDLSSLVWICTSTHSATKVIIIDANQPGNILDSFIVCNSHVLCIASVPGARETDYPAGEEGSQEVDPNQVDKSSLCGSMTSNSSAETDSMLGGITVVGCTAEGVTGAPVGHSANGASPMAEKQSDIANENNSVDDNIPTAEEATEATEVSAGTEDITDIGQTGVYTEHVFTDPLGVQNTEASPVYQPGTESELYKDVAVLPNEQDLVREEAQKMSSLLPTMWLGTQNGCLYVHSSVAHWRKCIHAIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRRESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETNKAAAGSGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVVCPQGSGGTELTSDKPAQESFSQGPLKSMLVISGGEGYIDFRMGDEGGESELLGEALQLEPSVAKAERSHLIVWQVMYGSE", "length": 1312, "header": "tr|A0A8V1AGY3-1|A0A8V1AGY3_CHICK Isoform 1 of C-Jun-amino-terminal kinase-interacting protein 4 OS=Gallus gallus OX=9031 GN=SPAG9 PE=1 SV=1 CANONICAL=A0A8V1AGY3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#A0A8V1ABM9-1", "sequence": { "sequence": "MLIKAYQQFEAEDNIQMEVVPNLVKPADLGVSRLEEREAELKKEYNALHSRHTEMIHNYMEHLERTKLHQLTGGDQLESTTHSRIRKERPISLGIFPLPPGDALLTPEAQREAGETPGSEHWKFHELSQPRSHTSLKDELSDVSQAGSKTTTPASTAASDVPALPAETPQKEDAEGFAKGTDMQNEKPDVSKNIEVQVAQETRNVSTGGNENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKQKLEEKNKELEEELKKARAEAEEARQKAKEDDDSDVPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTAKKPEPPVNVKYNAPTSHITPSVKKRSSTLSQLPSDKSKAFEFLSDETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGGQGDNKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYNDVAGTDADGNKQRTGSQSSLDRLDQELKDQQKELKHQEDLSSLVWICTSTHSATKVIIIDANQPGNILDSFIVCNSHVLCIASVPGARETDYPAGEEGSQEVDPNQVDKSSLCGSMTSNSSAETDSMLGGITVVGCTAEGVTGAPVGHSANGASPMAEKQSDIANENNSVDDNIPTAEEATEATEVSAGTEDITDIGQTGVYTEHVFTDPLGVQNTEASPVYQPGTESELYKDVAVLPNEQDLVREEAQKMSSLLPTMWLGTQNGCLYVHSSVAHWRKCIHAIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRRESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETNKAAAGSGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVVCPQGSGGTELTSDKPAQESFSQGPLKSMLVISGGEGYIDFRMGDEGGESELLGEALQLEPSVAKAERSHLIVWQVMYGSE", "length": 1195, "header": "tr|A0A8V1ABM9-1|A0A8V1ABM9_CHICK Computationally mapped isoform of Sperm associated antigen 9 OS=Gallus gallus OX=9031 GN=SPAG9 PE=1 SV=1 CANONICAL=A0A8V1AGY3-1" }, "locus": { "chromosome": "18", "start_pos": 10672835, "end_pos": 10623677, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070702.1", "url": "https://www.ensembl.org/id/ENSGALT00010070702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043393.1", "url": "https://www.ensembl.org/id/ENSGALP00010043393.1" } ] } }, { "isoform_ac": "A0A8V1AGY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#A0A8V1AGY3-1", "sequence": { "sequence": "MELADGVVYQEDPGGPGPAMMSERVSGLAGSIYREFERLIGRYDEEVVAELMPLVVAVLENLDSVCAHSQETSVELELLRDDNEQLLTQYEREKALRKQAEEKFIEFEDSQEQEKKDLQTRVEALESQTRQLELKAKNYADQISRLEEREAELKKEYNALHSRHTEMIHNYMEHLERTKLHQLTGGDQLESTTHSRIRKERPISLGIFPLPPGDALLTPEAQREAGETPGSEHWKFHELSQPRSHTSLKDELSDVSQAGSKTTTPASTAASDVPALPAETPQKEDAEGFAKGTDMQNEKPDVSKNIEVQVAQETRNVSTGVQNTGGNENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKQKLEEKNKELEEELKKARAEAEEARQKAKEDDDSDVPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTAKKPEPPVNVKYNAPTSHITPSVKKRSSTLSQLPSDKSKAFEFLSDETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGGQGDNKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYNDVAGTDADGNKQRTGSQSSLDRLDQELKDQQKELKHQEDLSSLVWICTSTHSATKVIIIDANQPGNILDSFIVCNSHVLCIASVPGARETDYPAGEEGSQEVDPNQVDKSSLCGSMTSNSSAETDSMLGGITVVGCTAEGVTGAPVGHSANGASPMAEKQSDIANENNSVDDNIPTAEEATEATEVSAGTEDITDIGQTGVYTEHVFTDPLGVQNTEASPVYQPGTESELYKDVAVLPNEQDLVREEAQKMSSLLPTMWLGTQNGCLYVHSSVAHWRKCIHAIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRRESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETNKAAAGSGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVVCPQGSGGTELTSDKPAQESFSQGPLKSMLVISGGEGYIDFRMGDEGGESELLGEALQLEPSVAKAERSHLIVWQVMYGSE", "length": 1312, "header": "tr|A0A8V1AGY3-1|A0A8V1AGY3_CHICK Isoform 1 of C-Jun-amino-terminal kinase-interacting protein 4 OS=Gallus gallus OX=9031 GN=SPAG9 PE=1 SV=1 CANONICAL=A0A8V1AGY3-1" }, "locus": { "chromosome": "18", "start_pos": 10672835, "end_pos": 10618101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070704.1", "url": "https://www.ensembl.org/id/ENSGALT00010070704.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043395.1", "url": "https://www.ensembl.org/id/ENSGALP00010043395.1" } ] } }, { "isoform_ac": "A0A8V1AJ06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#A0A8V1AJ06-1", "sequence": { "sequence": "MNPGCMLLFVFGFVGGAVVINSAILVSLSVLLLVHFSISTGVPALTQNLPRILRKERPISLGIFPLPPGDALLTPEAQREAGETPGSEHWKFHELSQPRSHTSLKDELSDVSQAGSKTTTPASTAASDVPALPAETPQKEDAEGFAKGTDMQNEKPDVSKNIEVQVAQETRNVSTGGNENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKQKLEEKNKELEEELKKARAEAEEARQKAKEDDDSDVPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTAKKPEPPVNVKYNAPTSHITPSVKKRSSTLSQLPSDKSKAFEFLSDETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGGQGDNKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYNDVAGTDADGNKQRTGSQSSLDRLDQELKDQQKELKHQEDLSSLVWICTSTHSATKVIIIDANQPGNILDSFIVCNSHVLCIASVPGARETDYPAGEEGSQEVDPNQVDKSSLCGSMTSNSSAETDSMLGGITVVGCTAEGVTGAPVGHSANGASPMAEKQSDIANENNSVDDNIPTAEEATEATEVSAGTEDITDIGQTGVYTEHVFTDPLGVQNTEASPVYQPGTESELYKDVAVLPNEQDLVREEAQKMSSLLPTMWLGTQNGCLYVHSSVAHWRKCIHAIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRRESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETVILHQGRLLGLRANKAAAGSGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVVCPQGSGGTELTSDKPAQESFSQGPLKSMLVISGGEGYIDFRMGDEGGESELLGEALQLEPSVAKAERSHLIVWQVMYGSE", "length": 1176, "header": "tr|A0A8V1AJ06-1|A0A8V1AJ06_CHICK Computationally mapped isoform of Sperm associated antigen 9 OS=Gallus gallus OX=9031 GN=SPAG9 PE=1 SV=1 CANONICAL=A0A8V1AGY3-1" }, "locus": { "chromosome": "18", "start_pos": 10672835, "end_pos": 10641445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070701.1", "url": "https://www.ensembl.org/id/ENSGALT00010070701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043392.1", "url": "https://www.ensembl.org/id/ENSGALP00010043392.1" } ] } }, { "isoform_ac": "A0A8V1AJ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#A0A8V1AJ10-1", "sequence": { "sequence": "MELADGVVYQEDPGGPGPAMMSERVSGLAGSIYREFERLIGRYDEEVVAELMPLVVAVLENLDSVCAHSQETSVELELLRDDNEQLLTQYEREKALRKQAEEKFIEFEDSQEQEKKDLQTRVEALESQTRQLELKAKNYADQISRLEEREAELKKEYNALHSRHTEMIHNYMEHLERTKLHQLTGGDQLESTTHSRIRKERPISLGIFPLPPGDALLTPEAQREAGETPGSEHWKFHELSQPRSHTSLKDELSDVSQAGSKTTTPASTAASDVPALPAETPQKEDAEGFAKGTDMQNEKPDVSKNIEVQVAQETRNVSTGGNENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKQKLEEKNKELEEELKKARAEAEEARQKAKEDDDSDVPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTAKKPEPPVNVKYNAPTSHITPSVKKRSSTLSQLPSDKSKAFEFLSDETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGGQGDNKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYNDVAGTDADGNKQRTGSQSSLDRLDQELKDQQKELKHQEDLSSLVWICTSTHSATKVIIIDANQPGNILDSFIVCNSHVLCIASVPGARETDYPAGEEGSQEVDPNQVDKSSLCGSMTSNSSAETDSMLGGITVVGCTAEGVTGAPVGHSANGASPMAEKQSDIANENNSVDDNIPTAEEATEATEVSAGTEDITDIGQTGVYTEHVFTDPLGVQNTEASPVYQPGTESELYKDVAVLPNEQDLVREEAQKMSSLLPTMWLGTQNGCLYVHSSVAHWRKCIHAIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRRESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGSGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVVCPQGSGGTELTSDKPAQESFSQGPLKSMLVISGGEGYIDFRMGDEGGESELLGEALQLEPSVAKAERSHLIVWQVMYGSE", "length": 1291, "header": "tr|A0A8V1AJ10-1|A0A8V1AJ10_CHICK Computationally mapped isoform of C-Jun-amino-terminal kinase-interacting protein 4 OS=Gallus gallus OX=9031 GN=SPAG9 PE=1 SV=1 CANONICAL=A0A8V1AGY3-1" }, "locus": { "chromosome": "18", "start_pos": 10672835, "end_pos": 10618101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070706.1", "url": "https://www.ensembl.org/id/ENSGALT00010070706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043397.1", "url": "https://www.ensembl.org/id/ENSGALP00010043397.1" } ] } }, { "isoform_ac": "A0A8V1AL51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#A0A8V1AL51-1", "sequence": { "sequence": "MELADGVVYQEDPGGPGPAMMSERVSGLAGSIYREFERLIGRYDEEVVAELMPLVVAVLENLDSVCAHSQETSVELELLRDDNEQLLTQYEREKALRKQAEEKFIEFEDSQEQEKKDLQTRVEALESQTRQLELKAKNYADQISRLEEREAELKKEYNALHSRHTEMIHNYMEHLERTKLHQLTGGDQLESTTHSRIRKERPISLGIFPLPPGDALLTPEAQREAGETPGSEHWKFHELSQPRSHTSLKDELSDVSQAGSKTTTPASTAASDVPALPAETPQKEDAEGFAKGTDMQNEKPDVSKNIEVQVAQETRNVSTGGNENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKQKLEEKNKELEEELKKARAEAEEARQKAKEDDDSDVPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFMPTRFSRLFSSSSNTAKKPEPPVNVKYNAPTSHITPSVKKRSSTLSQLPSDKSKAFEFLSDETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGGQGDNKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYNDVAGTDADGNKQRTGSQSSLDRLDQELKDQQKELKHQEDLSSLVWICTSTHSATKVIIIDANQPGNILDSFIVCNSHVLCIASVPGARETDYPAGEEGSQEVDPNQVDKSSLCGSMTSNSSAETDSMLGGITVVGCTAEGVTGAPVGHSANGASPMAEKQSDIANENNSVDDNIPTAEEATEATEVSAGTEDITDIGQTGVYTEHVFTDPLGVQNTEASPVYQPGTESELYKDVAVLPNEQDLVREEAQKMSSLLPTMWLGTQNGCLYVHSSVAHWRKCIHAIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRRESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETNKAAAGSGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVVCPQGSGGTELTSDKPAQESFSQGPLKSMLVISGGEGYIDFRMGDEGGESELLGEALQLEPSVAKAERSHLIVWQVMYGSE", "length": 1311, "header": "tr|A0A8V1AL51-1|A0A8V1AL51_CHICK Computationally mapped isoform of C-Jun-amino-terminal kinase-interacting protein 4 OS=Gallus gallus OX=9031 GN=SPAG9 PE=1 SV=1 CANONICAL=A0A8V1AGY3-1" }, "locus": { "chromosome": "18", "start_pos": 10672835, "end_pos": 10618101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070705.1", "url": "https://www.ensembl.org/id/ENSGALT00010070705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043396.1", "url": "https://www.ensembl.org/id/ENSGALP00010043396.1" } ] } }, { "isoform_ac": "A0A8V1AMS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3/entry#A0A8V1AMS4-1", "sequence": { "sequence": "MELADGVVYQEDPGGPGPAMMSERVSGLAGSIYREFERLIGRYDEEVVAELMPLVVAVLENLDSVCAHSQETSVELELLRDDNEQLLTQYEREKALRKQAEEKFIEFEDSQEQEKKDLQTRVEALESQTRQLELKAKNYADQISRLEEREAELKKEYNALHSRHTEVLLQNGQQPLLMIHNYMEHLERTKLHQLTGGDQLESTTHSRIRKERPISLGIFPLPPGDALLTPEAQREAGETPGSEHWKFHELSQPRSHTSLKDELSDVSQAGSKTTTPASTAASDVPALPAETPQKEDAEGFAKGTDMQNEKPDVSKNIEVQVAQETRNVSTGGNENEEKSEVQAIIESTPELDMDKDLSGYKGSSTPTKGIENKAFDRNTESLFEELSSAGSGLIGDVDEGADLLGMGREVENLILENTQLLETKNALNVVKNDLIAKVDELTCEKDVLQGELEAVKQAKQKLEEKNKELEEELKKARAEAEEARQKAKEDDDSDVPTAQRKRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENPAMQEKKRSSIWQFFSRLFSSSSNTAKKPEPPVNVKYNAPTSHITPSVKKRSSTLSQLPSDKSKAFEFLSDETEASLASRREQKREQYRQVKAHVQKEDGRVQAFGWSLPQKYKQVTNGGQGDNKMKNLPVPVYLRPLDEKDTSMKLWCAVGVNLSGGKTRDGGSVVGASVFYNDVAGTDADGNKQRTGSQSSLDRLDQELKDQQKELKHQEDLSSLVWICTSTHSATKVIIIDANQPGNILDSFIVCNSHVLCIASVPGARETDYPAGEEGSQEVDPNQVDKSSLCGSMTSNSSAETDSMLGGITVVGCTAEGVTGAPVGHSANGASPMAEKQSDIANENNSVDDNIPTAEEATEATEVSAGTEDITDIGQTGVYTEHVFTDPLGVQNTEASPVYQPGTESELYKDVAVLPNEQDLVREEAQKMSSLLPTMWLGTQNGCLYVHSSVAHWRKCIHAIKLKDSILSIVHVKGIVLVALADGTLAIFHRGVDGQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRRESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWVGTGNGVIISIPLTETNKAAAGSGNRPGSVIRVYGDENSDKVTPGTFIPYCSMAHAQLCFHGHRDAVKFFVAVPGQVVCPQGSGGTELTSDKPAQESFSQGPLKSMLVISGGEGYIDFRMGDEGGESELLGEALQLEPSVAKAERSHLIVWQVMYGSE", "length": 1318, "header": "tr|A0A8V1AMS4-1|A0A8V1AMS4_CHICK Computationally mapped isoform of C-Jun-amino-terminal kinase-interacting protein 4 OS=Gallus gallus OX=9031 GN=SPAG9 PE=1 SV=1 CANONICAL=A0A8V1AGY3-1" }, "locus": { "chromosome": "18", "start_pos": 10672835, "end_pos": 10618101, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070703.1", "url": "https://www.ensembl.org/id/ENSGALT00010070703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043394.1", "url": "https://www.ensembl.org/id/ENSGALP00010043394.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422095", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422095", "resource": "KEGG Pathway" }, { "id": "R-GGA-525793", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-525793", "resource": "Reactome", "description": "Myogenesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "MAP-kinase scaffold activity", "id": "GO:0005078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "JUN kinase binding", "id": "GO:0008432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008432", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 828, "end_pos": 830, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D4#function" }, { "database": "UniProtKB", "id": "A0A8V1A9D9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D9#function" }, { "database": "UniProtKB", "id": "A0A8V1AEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK0#function" }, { "database": "UniProtKB", "id": "A0A8V1AGY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY9#function" }, { "database": "UniProtKB", "id": "A0A8V1AGZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF618", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71", "locus": { "chromosome": "17", "start_pos": 1735183, "end_pos": 1875019, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028547", "url": "https://www.ensembl.org/id/ENSGALG00010028547" } ] } } ], "crossref": [ { "id": "A0A8V1AJ71", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ71", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9D4", "url": "https://www.orthodb.org/?gene=A0A8V1A9D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9D9", "url": "https://www.orthodb.org/?gene=A0A8V1A9D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEK0", "url": "https://www.orthodb.org/?gene=A0A8V1AEK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGY9", "url": "https://www.orthodb.org/?gene=A0A8V1AGY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGZ4", "url": "https://www.orthodb.org/?gene=A0A8V1AGZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ71", "url": "https://www.orthodb.org/?gene=A0A8V1AJ71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKZ1", "url": "https://www.orthodb.org/?gene=A0A8V1AKZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKZ5", "url": "https://www.orthodb.org/?gene=A0A8V1AKZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24383:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24383:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9D4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9D9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRPDGSAPAAAAATGAQADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLDGKAVERGSPVGYTRNRYSGTWIFDHALRYTSGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDDPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKFSRSPLFVAVKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 948, "header": "tr|A0A8V1AJ71-1|A0A8V1AJ71_CHICK Isoform 1 of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1A9D4-1", "sequence": { "sequence": "MQGWAPCVCGTWRAPVASPAWPRGDQSIISESEADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDDPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKFSRSPLFVAVKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 931, "header": "tr|A0A8V1A9D4-1|A0A8V1A9D4_CHICK Computationally mapped isoform of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1816471, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069133.1", "url": "https://www.ensembl.org/id/ENSGALT00010069133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042575.1", "url": "https://www.ensembl.org/id/ENSGALP00010042575.1" } ] } }, { "isoform_ac": "A0A8V1A9D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1A9D9-1", "sequence": { "sequence": "MNRPDGSAPAAAAATGAQADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLDGKAVERGSPVGYTRNRYSGTWIFDHALRYTSGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDDPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKFSRSPLFVAVKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 922, "header": "tr|A0A8V1A9D9-1|A0A8V1A9D9_CHICK Computationally mapped isoform of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1873957, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069138.1", "url": "https://www.ensembl.org/id/ENSGALT00010069138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042580.1", "url": "https://www.ensembl.org/id/ENSGALP00010042580.1" } ] } }, { "isoform_ac": "A0A8V1AEK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1AEK0-1", "sequence": { "sequence": "MNRPDGSAPAAAAATGAQADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDVFSVEGAPENRADPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIMKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 918, "header": "tr|A0A8V1AEK0-1|A0A8V1AEK0_CHICK Computationally mapped isoform of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1873957, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069135.1", "url": "https://www.ensembl.org/id/ENSGALT00010069135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042577.1", "url": "https://www.ensembl.org/id/ENSGALP00010042577.1" } ] } }, { "isoform_ac": "A0A8V1AGY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1AGY9-1", "sequence": { "sequence": "MSSVFQADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDVFSVEGAPENRADPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKSAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 853, "header": "tr|A0A8V1AGY9-1|A0A8V1AJ71_CHICK Computationally mapped isoform of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1810044, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069132.1", "url": "https://www.ensembl.org/id/ENSGALT00010069132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042574.1", "url": "https://www.ensembl.org/id/ENSGALP00010042574.1" } ] } }, { "isoform_ac": "A0A8V1AGZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1AGZ4-1", "sequence": { "sequence": "MNRPDGSAPAAAAATGAQADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDNFRYTCDICGKKYKYYSCFQEHRDLHAVDDPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKFSRSPLFVAVKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 903, "header": "tr|A0A8V1AGZ4-1|A0A8V1AGZ4_CHICK Computationally mapped isoform of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1873957, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069137.1", "url": "https://www.ensembl.org/id/ENSGALT00010069137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042579.1", "url": "https://www.ensembl.org/id/ENSGALP00010042579.1" } ] } }, { "isoform_ac": "A0A8V1AJ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1AJ71-1", "sequence": { "sequence": "MNRPDGSAPAAAAATGAQADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLDGKAVERGSPVGYTRNRYSGTWIFDHALRYTSGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDDPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKFSRSPLFVAVKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 948, "header": "tr|A0A8V1AJ71-1|A0A8V1AJ71_CHICK Isoform 1 of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1873957, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069136.1", "url": "https://www.ensembl.org/id/ENSGALT00010069136.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042578.1", "url": "https://www.ensembl.org/id/ENSGALP00010042578.1" } ] } }, { "isoform_ac": "A0A8V1AKZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1AKZ1-1", "sequence": { "sequence": "MNADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDDPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKFSRSPLFVAVKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITAESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 875, "header": "tr|A0A8V1AKZ1-1|A0A8V1AKZ1_CHICK Computationally mapped isoform of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1865853, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069134.1", "url": "https://www.ensembl.org/id/ENSGALT00010069134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042576.1", "url": "https://www.ensembl.org/id/ENSGALP00010042576.1" } ] } }, { "isoform_ac": "A0A8V1AKZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71/entry#A0A8V1AKZ5-1", "sequence": { "sequence": "MLRKGDRRQADESNSSGRRSSSSRECLKRSPRSPKAEGSDSVTSQSSPSEEAGMMTEVKVKTEVPDDYIEEVIWQDDTKDSKKNIKDGPGDVPAEICVVIGGVRNQQTLGSYECGICGKKYKYYNCFQTHVRAHRDTEAASGEGASQGNNFRYTCDICGKKYKYYSCFQEHRDLHAVDDPYDQAVIAAEEVKEEEPEPFQKIGPKTGNYTCEFCGKQYKYYTPYQEHVALHAPIKFSRSPLFVAVKTQGSQSSKKTPTSINRCSTLLHRTPSGVPPTSQSQMFRAPNSGSPGSKAITESAFSRRVEGKAQNNFEETNSNSQNSSAVHSGTEKPKEKRCKQNPSEPYTCGACGIQFQFYNNLLEHMQSHAADNENNIASSQPRSPLPVVEEKWKPQLQRNNTNNTSASGSVGNSTIPEKERQNIAERLLRVMCTDLGALSVVSGKEFIKLAQTLVDSGARYGAFSVTEILGNFNTLALKHLPRMYNQVKVKVTCALGSNACLGIGVTCHSQSIGPDSCYILTAYQVEGNHIKSYVLGIKGVDIRDNGDFIHHWVQNVLSEFVMSEIRTVYVTDCKVNSSAFSKAGMCLRCSACALNSVVQSVLNKRTLQARNMHEVIELLNVCEDLAGSTGLSKETFGSLEETSPPPCWNSVTDSLLLVHERYEQICEFYSRAKKMNLIQNLNKHLLSNLAAILAPVKQAVIELSNESRPTLQLVLPTYVKLEKLFTSKANDAGVVSKLCHLFLEALKENFKVHSAHKVAMILDPQQKLRPVPPYQHEEIIGKVCELINEVKESWAEETEFEPSTKKPRAAGEAAAAQEEDWFGKNEVYDYLQEPLFQATPDLFQYWSCVTQKHTKLAKLAFWLLAVPAVGARSECVNMCEQALLIKRRRLLSPEDMNKLMFLKSNML", "length": 907, "header": "tr|A0A8V1AKZ5-1|A0A8V1AKZ5_CHICK Computationally mapped isoform of Zinc finger protein 618 OS=Gallus gallus OX=9031 GN=ZNF618 PE=3 SV=1 CANONICAL=A0A8V1AJ71-1" }, "locus": { "chromosome": "17", "start_pos": 1875019, "end_pos": 1735797, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069139.1", "url": "https://www.ensembl.org/id/ENSGALT00010069139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042581.1", "url": "https://www.ensembl.org/id/ENSGALP00010042581.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" }, { "name": "transcription coregulator binding", "id": "GO:0001221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJ71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ71" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 180, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 23, 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGZ0-1", "uniprot_ac": "A0A8V1AGZ0", "uniprot_id": "A0A8V1AGZ0_CHICK", "mass": { "chemical_mass": 29125.0, "monoisotopic_mass": 29125.0 }, "refseq": {}, "gene_names": [ { "name": "IER5L", "type": "recommended", "evidence": [ { "id": "A0A8V1AGZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ0" } ] } ], "protein_names": [ { "name": "Immediate early response 5 like", "type": "synonym", "evidence": [ { "id": "A0A8V1AGZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IER5L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ0", "locus": { "chromosome": "17", "start_pos": 6141229, "end_pos": 6142503, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028005", "url": "https://www.ensembl.org/id/ENSGALG00010028005" } ] } } ], "crossref": [ { "id": "A0A8V1AGZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGZ0", "url": "https://www.orthodb.org/?gene=A0A8V1AGZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15895", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15895", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05760", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05760", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRGRRRRMECTLDAQSLISISLRKIHSSRTQRGGIKLHKNLLVSYVLRNARQLYLSERYAELYRRQQHYPDGAPLLAVPPPCPPPPPSAPPEMPPLPGDPHERDVPLCSAPPELQQRAPCRDSAGFYRAAPAGHGAGHGAGAAPPYAAAASSGCDFGSGGGTQQHCSSRTTVLDLDTHVVTTVENGYLHQECCSQCPCCCQPAAPGPPSPPPPPGAKRKYYPGQEEEEGVEEGEPGEAGWRAAPNSPRAPNAPASRSTAAPNTRRTLPTSPT", "length": 273, "header": "tr|A0A8V1AGZ0-1|A0A8V1AGZ0_CHICK Isoform 1 of Immediate early response 5 like OS=Gallus gallus OX=9031 GN=IER5L PE=3 SV=1 CANONICAL=A0A8V1AGZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ0/entry#A0A8V1AGZ0-1", "sequence": { "sequence": "MLRGRRRRMECTLDAQSLISISLRKIHSSRTQRGGIKLHKNLLVSYVLRNARQLYLSERYAELYRRQQHYPDGAPLLAVPPPCPPPPPSAPPEMPPLPGDPHERDVPLCSAPPELQQRAPCRDSAGFYRAAPAGHGAGHGAGAAPPYAAAASSGCDFGSGGGTQQHCSSRTTVLDLDTHVVTTVENGYLHQECCSQCPCCCQPAAPGPPSPPPPPGAKRKYYPGQEEEEGVEEGEPGEAGWRAAPNSPRAPNAPASRSTAAPNTRRTLPTSPT", "length": 273, "header": "tr|A0A8V1AGZ0-1|A0A8V1AGZ0_CHICK Isoform 1 of Immediate early response 5 like OS=Gallus gallus OX=9031 GN=IER5L PE=3 SV=1 CANONICAL=A0A8V1AGZ0-1" }, "locus": { "chromosome": "17", "start_pos": 6142304, "end_pos": 6141438, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067882.1", "url": "https://www.ensembl.org/id/ENSGALT00010067882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041625.1", "url": "https://www.ensembl.org/id/ENSGALP00010041625.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJ27-1", "uniprot_ac": "A0A8V1AJ27", "uniprot_id": "A0A8V1AJ27_CHICK", "mass": { "chemical_mass": 89144.0, "monoisotopic_mass": 89144.0 }, "refseq": {}, "gene_names": [ { "name": "RAP1GAP2", "type": "recommended", "evidence": [ { "id": "A0A8V1AJ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ] } ], "protein_names": [ { "name": "RAP1 GTPase activating protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AJ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UF91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF91#function" }, { "database": "UniProtKB", "id": "ARBA00057316", "url": "https://www.uniprot.org/uniprotkb/ARBA00057316#function" }, { "database": "UniProtKB", "id": "A0A8V1AGZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ1#function" }, { "database": "UniProtKB", "id": "A0A8V1AGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ6#function" }, { "database": "UniProtKB", "id": "A0A8V1AH00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH00#function" }, { "database": "UniProtKB", "id": "A0A8V1AMT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT5#function" }, { "database": "UniProtKB", "id": "A0A8V1ABQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ2#function" }, { "database": "UniProtKB", "id": "A0A8V1ABP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP2#function" }, { "database": "UniProtKB", "id": "A0A8V1ABP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP7#function" }, { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAP1GAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27", "locus": { "chromosome": "19", "start_pos": 10054146, "end_pos": 10002761, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029255", "url": "https://www.ensembl.org/id/ENSGALG00010029255" } ] } } ], "crossref": [ { "id": "A0A8V1AJ27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ27", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033885", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033885", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UF91", "url": "https://www.orthodb.org/?gene=A0A3Q2UF91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABP2", "url": "https://www.orthodb.org/?gene=A0A8V1ABP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABP7", "url": "https://www.orthodb.org/?gene=A0A8V1ABP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABQ2", "url": "https://www.orthodb.org/?gene=A0A8V1ABQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGZ1", "url": "https://www.orthodb.org/?gene=A0A8V1AGZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGZ6", "url": "https://www.orthodb.org/?gene=A0A8V1AGZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH00", "url": "https://www.orthodb.org/?gene=A0A8V1AH00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ27", "url": "https://www.orthodb.org/?gene=A0A8V1AJ27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMT5", "url": "https://www.orthodb.org/?gene=A0A8V1AMT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-392517", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UF91", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UF91-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPALQLFVVCLSVHEELQWDFGGMSGGAAPGMAPGWGCGNAVRLRARLRYVREGRFRIEERTLTAFQWLYSPQQHRIVSRADLGSPSRIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 806, "header": "tr|A0A8V1AJ27-1|A0A8V1AJ27_CHICK Isoform 1 of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UF91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A3Q2UF91-1", "sequence": { "sequence": "MWRLGCRSIRIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 726, "header": "tr|A0A3Q2UF91-1|A0A3Q2UF91_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10007061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070725.1", "url": "https://www.ensembl.org/id/ENSGALT00010070725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043416.1", "url": "https://www.ensembl.org/id/ENSGALP00010043416.1" } ] } }, { "isoform_ac": "A0A8V1ABP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1ABP2-1", "sequence": { "sequence": "MSRADAGRMHSRRAGIRAAVVLIGLLHKSRKQNKEKRKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTDIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 729, "header": "tr|A0A8V1ABP2-1|A0A8V1ABP2_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10029880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070717.1", "url": "https://www.ensembl.org/id/ENSGALT00010070717.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043408.1", "url": "https://www.ensembl.org/id/ENSGALP00010043408.1" } ] } }, { "isoform_ac": "A0A8V1ABP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1ABP7-1", "sequence": { "sequence": "MGWRSCSQRGSGCRPKDRRVFWPFCLELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTDIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 727, "header": "tr|A0A8V1ABP7-1|A0A8V1ABP7_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10020782, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070722.1", "url": "https://www.ensembl.org/id/ENSGALT00010070722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043413.1", "url": "https://www.ensembl.org/id/ENSGALP00010043413.1" } ] } }, { "isoform_ac": "A0A8V1ABQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1ABQ2-1", "sequence": { "sequence": "MASGKAEGERRWELVRWYVREGRFRIEERTLTAFQWLYSPQQHRIVSRADLGSPSRIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 772, "header": "tr|A0A8V1ABQ2-1|A0A8V1ABQ2_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10002960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070727.1", "url": "https://www.ensembl.org/id/ENSGALT00010070727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043418.1", "url": "https://www.ensembl.org/id/ENSGALP00010043418.1" } ] } }, { "isoform_ac": "A0A8V1AGZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1AGZ1-1", "sequence": { "sequence": "MDFLRGLLSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 684, "header": "tr|A0A8V1AGZ1-1|A0A8V1AJ27_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10038612, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070714.1", "url": "https://www.ensembl.org/id/ENSGALT00010070714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043405.1", "url": "https://www.ensembl.org/id/ENSGALP00010043405.1" } ] } }, { "isoform_ac": "A0A8V1AGZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1AGZ6-1", "sequence": { "sequence": "MSRADAGRMHSRRAGIRAAVVLIGLLHKSRKQNKEKRKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 741, "header": "tr|A0A8V1AGZ6-1|A0A8V1AGZ6_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10029880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070719.1", "url": "https://www.ensembl.org/id/ENSGALT00010070719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043410.1", "url": "https://www.ensembl.org/id/ENSGALP00010043410.1" } ] } }, { "isoform_ac": "A0A8V1AH00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1AH00-1", "sequence": { "sequence": "MCMRLGARRGAANLAASGSPALAGSGSPLCAPCSMLPARPPRPPATASRQRRAATMFQRKRSVSFGGYGWIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 786, "header": "tr|A0A8V1AH00-1|A0A8V1AH00_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10012070, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070724.1", "url": "https://www.ensembl.org/id/ENSGALT00010070724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043415.1", "url": "https://www.ensembl.org/id/ENSGALP00010043415.1" } ] } }, { "isoform_ac": "A0A8V1AJ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1AJ27-1", "sequence": { "sequence": "MSPPALQLFVVCLSVHEELQWDFGGMSGGAAPGMAPGWGCGNAVRLRARLRYVREGRFRIEERTLTAFQWLYSPQQHRIVSRADLGSPSRIDKTMLASLKMKKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 806, "header": "tr|A0A8V1AJ27-1|A0A8V1AJ27_CHICK Isoform 1 of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10004626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070726.1", "url": "https://www.ensembl.org/id/ENSGALT00010070726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043417.1", "url": "https://www.ensembl.org/id/ENSGALP00010043417.1" } ] } }, { "isoform_ac": "A0A8V1AMT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27/entry#A0A8V1AMT5-1", "sequence": { "sequence": "MLQRGSAGGGRLAVLASWSGCARPHSVLGGIGTHLQVQSGSKCAAELQASSCCSGAAAELLPLGPASKMPRKLWKQELLSSADVTLPERPLSPPLTAPPTMKSAEFFEMLEKMQAPKLEDQKAGSQKHKEDYIPYPSIDEILEKGSPYPLVILPQFGGYWIEDPENLGTPTSSDSSVCEEEEENFSPSPYGYKLECKGEARAYRKHFLGKDHLNFYCTASSLGNLILSIKCEEVDGTEYLRIILRSKVKTLHERIPLAGFSKLPSIPQIAKAFCDDASGLKFNPVLYPKASQMIVAYDEHEVNNTFKFGVIYQKFRQTQEEELFGNNEESAAFRNFLNLLGDTITLQDFKGFRGGLDVSHGQTGVESVYTVFRDREIMFHVSTKLPFTEGDTQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVENPDADTTSYKVSVTAREDVPSFGPPLPSPPVFQKSPEFREFLLTKLINAENACCKSDKFAKLEDRTRAALLDNLHDELHGHTQTMLGLGPEEDKLENGGHGGFLESFKRAIRVRSHSMETMVGSQRKQHGGGIPGSLSGGIAHNSGEVTKTTFSPPVSAATAKNQSRSPIKRRSGLFPRLHTGLESQVDSRARCDSISGPQKTPDVGHSSQEMKSETSSNPSSPEICPNKDRPFVKLKENGRSNISRSSSSTSSFSSTAGESETLEEYDSVGSQPSTASPFKQDVFIYSASPGSDSPSVGAAATPVIMSRSPTADIKNRNSPRSNLKFRFDKLSHGSSSTSH", "length": 778, "header": "tr|A0A8V1AMT5-1|A0A8V1AMT5_CHICK Computationally mapped isoform of RAP1 GTPase activating protein 2 OS=Gallus gallus OX=9031 GN=RAP1GAP2 PE=4 SV=1 CANONICAL=A0A8V1AJ27-1" }, "locus": { "chromosome": "19", "start_pos": 10051400, "end_pos": 10016553, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070723.1", "url": "https://www.ensembl.org/id/ENSGALT00010070723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043414.1", "url": "https://www.ensembl.org/id/ENSGALP00010043414.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-392517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "resource": "Reactome", "description": "Rap1 signalling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "pmid": "" }, { "name": "regulation of cell size", "id": "GO:0008361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008361", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ27" }, { "id": "PS50085", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rap-GAP", "eco_id": "ECO_0000259", "start_pos": 322, "end_pos": 538, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 708, "end_pos": 710 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AGZ7-1", "uniprot_ac": "A0A8V1AGZ7", "uniprot_id": "A0A8V1AGZ7_CHICK", "mass": { "chemical_mass": 23632.0, "monoisotopic_mass": 23632.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Growth arrest and DNA damage inducible beta", "type": "synonym", "evidence": [ { "id": "A0A8V1AGZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AGZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10411:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10411:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGQPQEGSDTEPRGRKAAPLLLPLLLLLLTTTARSSRTLRPAAPGGRKEKRGSRRTISRQKIPRLRRCDSGAAAARITARRASVPSFGLYRDMTLEELLPCDSPRDPDSVVLCVLATDEEDEGDIALQIHFTLIQAFCCDNDIHIVRVAGMRRLAAVLGEPAPGAEPRDLHCLLVTMPHADAWQSHGLAEVANYCAESRDRNQWVPVVRLQER", "length": 214, "header": "tr|A0A8V1AGZ7-1|A0A8V1AGZ7_CHICK Isoform 1 of Growth arrest and DNA damage inducible beta OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AGZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7/entry#A0A8V1AGZ7-1", "sequence": { "sequence": "MDGQPQEGSDTEPRGRKAAPLLLPLLLLLLTTTARSSRTLRPAAPGGRKEKRGSRRTISRQKIPRLRRCDSGAAAARITARRASVPSFGLYRDMTLEELLPCDSPRDPDSVVLCVLATDEEDEGDIALQIHFTLIQAFCCDNDIHIVRVAGMRRLAAVLGEPAPGAEPRDLHCLLVTMPHADAWQSHGLAEVANYCAESRDRNQWVPVVRLQER", "length": 214, "header": "tr|A0A8V1AGZ7-1|A0A8V1AGZ7_CHICK Isoform 1 of Growth arrest and DNA damage inducible beta OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AGZ7-1" }, "locus": { "chromosome": "28", "start_pos": 3747908, "end_pos": 3744871, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066799.1", "url": "https://www.ensembl.org/id/ENSGALT00010066799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040878.1", "url": "https://www.ensembl.org/id/ENSGALP00010040878.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" } ], "pmid": "" }, { "name": "positive regulation of p38MAPK cascade", "id": "GO:1900745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGZ7" }, { "id": "PF01248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal protein eL8/eL30/eS12/Gadd45", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 164, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AH04-1", "uniprot_ac": "A0A8V1AH04", "uniprot_id": "A0A8V1AH04_CHICK", "mass": { "chemical_mass": 45998.0, "monoisotopic_mass": 45998.0 }, "refseq": {}, "gene_names": [ { "name": "POC1A", "type": "recommended", "evidence": [ { "id": "A0A8V1AH04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04" } ] } ], "protein_names": [ { "name": "POC1 centriolar protein homolog A", "type": "recommended", "evidence": [ { "id": "A0A8V1AH04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04/entry#names_and_taxonomy" } ] }, { "name": "Pat-interacting protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AH04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 51A", "type": "synonym", "evidence": [ { "id": "A0A8V1AH04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play an important role in centriole assembly and/or stability and ciliogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AEI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI0#function" }, { "database": "UniProtKB", "id": "ARBA00058716", "url": 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415889", "url": "https://www.ncbi.nlm.nih.gov/gene/415889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6T9", "url": "https://www.orthodb.org/?gene=A0A8V1A6T9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEI0", "url": "https://www.orthodb.org/?gene=A0A8V1AEI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH04", "url": "https://www.orthodb.org/?gene=A0A8V1AH04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIT8", "url": "https://www.orthodb.org/?gene=A0A8V1AIT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44019:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44019:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A6T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGPLVLPRPGCRAGDPSLERHFRGHRDAITSVDFSLNKKQLASGSMDSCLKIWSMKPQMRAYCLVGHKDAVMCVQFSPSGHLVASGSRDKTVCLWVPSVKGESTVFKAHTATVRSVHFSSDGQSLVTASDDKTIKVWTVHRQKFLFSLSQHINWVRCARFSPDGRLIASASDDKTVKLWDKTSRECIHSFCEHGGFANHVEFHPSGTCIAAAGTDKTVKVWDVRMNRLLQHYQVHTAAVNSLSFHPSGNYLITASNDSTLKILDLLEGRLLYTLHGHQGPATCVAFSRTGDFFASGGSDEQVMVWKTNFSAADYDGVLKTHKSGATVDGTHHRLPPEMDCGVHLKKTKSQDTGRNHERQEEDVHLADTLEHIIGQLDVLTQTVSILEQRLTLTENKLKEFLENQQKIIQNKEN", "length": 414, "header": "tr|A0A8V1AH04-1|A0A8V1AH04_CHICK Isoform 1 of POC1 centriolar protein homolog A OS=Gallus gallus OX=9031 GN=POC1A PE=3 SV=1 CANONICAL=A0A8V1AH04-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04/entry#A0A8V1A6T9-1", "sequence": { "sequence": "MAAGGAEDPSLERHFRGHRDAITSVDFSLNKKQLASGSMDSCLKIWSMKPQMRAYCLVGHKDAVMCVQFSPSGHLVASGSRDKTVCLWVPSVKGESTVFKAHTATVRSVHFSSDGQSLVTASDDKTIKVWTVHRQKFLFSLSQHINWVRCARFSPDGRLIASASDDKTVKLWDKTSRECIHSFCEHGGFANHVEFHPSGTCIAAAGTDKTVKVWDVRMNRLLQHYQVHTAAVNSLSFHPSGNYLITASNDSTLKILDLLEGRLLYTLHGHQGPATCVAFSRTGDFFASGGSDEQPPEMDCGVHLKKTKSQDTGRNHERQEEDVHLADTLEHIIGQLDVLTQTVSILEQRLTLTENKLKEFLENQQKIIQNKEN", "length": 373, "header": "tr|A0A8V1A6T9-1|A0A8V1A6T9_CHICK Computationally mapped isoform of POC1 centriolar protein homolog A OS=Gallus gallus OX=9031 GN=POC1A PE=3 SV=1 CANONICAL=A0A8V1AH04-1" }, "locus": { "chromosome": "12", "start_pos": 254768, "end_pos": 183466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067894.1", "url": "https://www.ensembl.org/id/ENSGALT00010067894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041637.1", "url": "https://www.ensembl.org/id/ENSGALP00010041637.1" } ] } }, { "isoform_ac": "A0A8V1AEI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04/entry#A0A8V1AEI0-1", "sequence": { "sequence": "MGGPLVLPRPGCRAGDPSLERHFRGHRDAITSVDFSLNKKQLASGSMDSCLKIWSMKPQMRAYCLVGHKDAVMCVQFSPSGHLVASGSRDKTVCLWVPSVKGESTVFKAHTATVRSVHFSSDGQSLVTASDDKTIKVWTVHRQKFLFSLSQHINWVRCARFSPDGRLIASASDDKTVKLWDKTSRECIHSFCEHGGFANHVEFHPSGTCIAAAGTDKTVKVWDVRMNRLLQHYQVHTAAVNSLSFHPSGNYLITASNDSTLKILDLLEGRLLYTLHGHQGPATCVAFSRTGDFFASGGSDEQVMVWKTNFSAADYDGVLKTHKSGATVDGTHHRLTVSILEQRLTLTENKLKEFLENQQKIIQNKEN", "length": 367, "header": "tr|A0A8V1AEI0-1|A0A8V1AEI0_CHICK Computationally mapped isoform of POC1 centriolar protein homolog A OS=Gallus gallus OX=9031 GN=POC1A PE=3 SV=1 CANONICAL=A0A8V1AH04-1" }, "locus": { "chromosome": "12", "start_pos": 254768, "end_pos": 183591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067898.1", "url": "https://www.ensembl.org/id/ENSGALT00010067898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041641.1", "url": "https://www.ensembl.org/id/ENSGALP00010041641.1" } ] } }, { "isoform_ac": "A0A8V1AH04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04/entry#A0A8V1AH04-1", "sequence": { "sequence": "MGGPLVLPRPGCRAGDPSLERHFRGHRDAITSVDFSLNKKQLASGSMDSCLKIWSMKPQMRAYCLVGHKDAVMCVQFSPSGHLVASGSRDKTVCLWVPSVKGESTVFKAHTATVRSVHFSSDGQSLVTASDDKTIKVWTVHRQKFLFSLSQHINWVRCARFSPDGRLIASASDDKTVKLWDKTSRECIHSFCEHGGFANHVEFHPSGTCIAAAGTDKTVKVWDVRMNRLLQHYQVHTAAVNSLSFHPSGNYLITASNDSTLKILDLLEGRLLYTLHGHQGPATCVAFSRTGDFFASGGSDEQVMVWKTNFSAADYDGVLKTHKSGATVDGTHHRLPPEMDCGVHLKKTKSQDTGRNHERQEEDVHLADTLEHIIGQLDVLTQTVSILEQRLTLTENKLKEFLENQQKIIQNKEN", "length": 414, "header": "tr|A0A8V1AH04-1|A0A8V1AH04_CHICK Isoform 1 of POC1 centriolar protein homolog A OS=Gallus gallus OX=9031 GN=POC1A PE=3 SV=1 CANONICAL=A0A8V1AH04-1" }, "locus": { "chromosome": "12", "start_pos": 254768, "end_pos": 183591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067897.1", "url": "https://www.ensembl.org/id/ENSGALT00010067897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041640.1", "url": "https://www.ensembl.org/id/ENSGALP00010041640.1" } ] } }, { "isoform_ac": "A0A8V1AIT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04/entry#A0A8V1AIT8-1", "sequence": { "sequence": "MDSCLKIWSMKPQMRAYCLVGHKDAVMCVQFSPSGHLVASGSRDKTVCLWVPSVKGESTVFKAHTATVRSVHFSSDGQSLVTASDDKTIKVWTVHRQKFLFSLSQHINWVRCARFSPDGRLIASASDDKTVKLWDKTSRECIHSFCEHGGFANHVEFHPSGTCIAAAGTDKTVKVWDVRMNRLLQHYQVHTAAVNSLSFHPSGNYLITASNDSTLKILDLLEGRLLYTLHGHQGPATCVAFSRTGDFFASGGSDEQVMVWKTNFSAADYDGVLKTHKSGATVDGTHHRLPPEMDCGVHLKKTKSQDTGRNHERQEEDVHLADTLEHIIGQLDVLTQTVSILEQRLTLTENKLKEFLENQQKIIQNKEN", "length": 368, "header": "tr|A0A8V1AIT8-1|A0A8V1AIT8_CHICK Computationally mapped isoform of POC1 centriolar protein homolog A OS=Gallus gallus OX=9031 GN=POC1A PE=3 SV=1 CANONICAL=A0A8V1AH04-1" }, "locus": { "chromosome": "12", "start_pos": 254768, "end_pos": 187906, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067895.1", "url": "https://www.ensembl.org/id/ENSGALT00010067895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041638.1", "url": "https://www.ensembl.org/id/ENSGALP00010041638.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04" } ], "pmid": "" }, { "name": "microtubule-based process", "id": "GO:0007017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04" } ], "pmid": "" }, { "name": "multicellular organismal-level homeostasis", "id": "GO:0048871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048871", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 309, "end_pos": 311 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AH12-1", "uniprot_ac": "A0A8V1AH12", "uniprot_id": "A0A8V1AH12_CHICK", "mass": { "chemical_mass": 24061.0, "monoisotopic_mass": 24061.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12", "locus": {} } ], "crossref": [ { "id": "A0A8V1AH12", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH12", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24356:SF136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24356:SF136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "TFAENPLCKCMAETVLGLEYLHNYGIVHFDLKPDNLLITSIGHIKLTDFGLSKIGLMSLTTNLYVCGTLEYTAPEVILWQGYGKPVDCWAMGVILYEFLVGCIPFFRDTPEELFGQVISDGTAWPEGDDTLPPDAQDLISKLLHQNPLERMGTGSAFEMKQHRFFKDLDWNGLLWQKAELISHLESEDDTSYFDTHSKRYQHLDIKLYRY", "length": 210, "header": "tr|A0A8V1AH12-1|A0A8V1AH12_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AH12-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12/entry#A0A8V1AH12-1", "sequence": { "sequence": "TFAENPLCKCMAETVLGLEYLHNYGIVHFDLKPDNLLITSIGHIKLTDFGLSKIGLMSLTTNLYVCGTLEYTAPEVILWQGYGKPVDCWAMGVILYEFLVGCIPFFRDTPEELFGQVISDGTAWPEGDDTLPPDAQDLISKLLHQNPLERMGTGSAFEMKQHRFFKDLDWNGLLWQKAELISHLESEDDTSYFDTHSKRYQHLDIKLYRY", "length": 210, "header": "tr|A0A8V1AH12-1|A0A8V1AH12_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AH12-1" }, "locus": { "chromosome": "12", "start_pos": 380939, "end_pos": 380139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067908.1", "url": "https://www.ensembl.org/id/ENSGALT00010067908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041651.1", "url": "https://www.ensembl.org/id/ENSGALP00010041651.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + 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"https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJS0" } ] } ] }, { "uniprot_ac": "Q5ZKI0", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q5ZKI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKI0" } ] } ] }, { "uniprot_ac": "Q5ZKN1", "gene_name": "CDK9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": 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} ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", 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supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On Oct 15, 2021 this sequence version replaced NP_001264736.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. 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[], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106470", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26", "locus": {} } ], "crossref": [ { "id": "A0A8V1AH26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH26", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07572", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07572", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MRVAVCQ", "url": "https://omabrowser.org/oma/group/MRVAVCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6W6", "url": "https://www.orthodb.org/?gene=A0A8V1A6W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH26", "url": "https://www.orthodb.org/?gene=A0A8V1AH26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23088:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23088:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00795", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00795", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A6W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGPRGQSEGVLLAVRRSLKRGSLCAPLPRLSAVLRLPLHRFCAGPRSPLGSHQAMAASLGPKPLVAVGQVTSTPDKEQNFSGCAALVRAAARRGACLVFLPEGFDYIGRDSAQTLSLAESLDGDLMARYSTLARDCGVWLSLGGFHERRADWPSTQRIYNCHVLLDPTGRLAAAYRKTHLCDVELEGRVTMKESSFTNPGTEIVPPISTPAGMLGLSICYDLRFPEISLALRHAGAEILTYPSAFTFPTGSAHWEVLLRARAIETQCYVVAAAQTGRNHEGRVSYGHTLVADPWGAVVAQCSEGPGLCYAEIDLEYLRRVRREIPVQSHRRADLYGTVGLQAALSVP", "length": 348, "header": "tr|A0A8V1AH26-1|A0A8V1AH26_CHICK Isoform 1 of Deaminated glutathione amidase OS=Gallus gallus OX=9031 GN=LOC121106470 PE=3 SV=1 CANONICAL=A0A8V1AH26-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26/entry#A0A8V1A6W6-1", "sequence": { "sequence": "MVRLSAVLRLPLHRFCAGPRSPLGSHQAMAASLGPKPLVAVGQVTSTPDKEQNFSGCAALVRAAARRGACLVFLPEGFDYIGRDSAQTLSLAESLDGDLMARYSTLARDCGVWLSLGGFHERRADWPSTQRIYNCHVLLDPTGRLAAAYRKTHLCDVELEGRVTMKESSFTNPGTEIVPPISTPAGMLGLSICYDLRFPEISLALRHAGAEILTYPSAFTFPTGSAHWEVLLRARAIETQCYVVAAAQTGRNHEGRVSYGHTLVADPWGAVVAQCSEGPGLCYAEIDLEYLRRVRREIPVQSHRRADLYGTVGLQAALSVP", "length": 321, "header": "tr|A0A8V1A6W6-1|A0A8V1A6W6_CHICK Computationally mapped isoform of Deaminated glutathione amidase OS=Gallus gallus OX=9031 GN=LOC121106470 PE=3 SV=1 CANONICAL=A0A8V1AH26-1" }, "locus": { "chromosome": "25", "start_pos": 2861849, "end_pos": 2859334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067926.1", "url": "https://www.ensembl.org/id/ENSGALT00010067926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041669.1", "url": "https://www.ensembl.org/id/ENSGALP00010041669.1" } ] } }, { "isoform_ac": "A0A8V1AH26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26/entry#A0A8V1AH26-1", "sequence": { "sequence": "MYGPRGQSEGVLLAVRRSLKRGSLCAPLPRLSAVLRLPLHRFCAGPRSPLGSHQAMAASLGPKPLVAVGQVTSTPDKEQNFSGCAALVRAAARRGACLVFLPEGFDYIGRDSAQTLSLAESLDGDLMARYSTLARDCGVWLSLGGFHERRADWPSTQRIYNCHVLLDPTGRLAAAYRKTHLCDVELEGRVTMKESSFTNPGTEIVPPISTPAGMLGLSICYDLRFPEISLALRHAGAEILTYPSAFTFPTGSAHWEVLLRARAIETQCYVVAAAQTGRNHEGRVSYGHTLVADPWGAVVAQCSEGPGLCYAEIDLEYLRRVRREIPVQSHRRADLYGTVGLQAALSVP", "length": 348, "header": "tr|A0A8V1AH26-1|A0A8V1AH26_CHICK Isoform 1 of Deaminated glutathione amidase OS=Gallus gallus OX=9031 GN=LOC121106470 PE=3 SV=1 CANONICAL=A0A8V1AH26-1" }, "locus": { "chromosome": "25", "start_pos": 2861745, "end_pos": 2859334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067924.1", "url": "https://www.ensembl.org/id/ENSGALT00010067924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041667.1", "url": "https://www.ensembl.org/id/ENSGALP00010041667.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A424-1", "protein_name": "Deaminated glutathione amidase", "gene_name": "NIT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLAVPSCRTCYLARPPRLGFIIRPPHQLLSLLLGPRLRILRLSILCAQPRPRSMAISSSSWDLPLVAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFDFIGRDPEETLRLSEPLGGKLLGEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVILNNTGSVVATYRKTHLCDVEIPGQGPMCESNSTIPGPSLEPPVSTPAGKIGLAICYDMRFPELSLALVQAGAEILTYPSAFGSVTGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLNYLRQLRQHLPVFQHRRPDLYGSLGHPLS", "length": 345 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HU11-1", "protein_name": "Deaminated glutathione amidase", "gene_name": "Nit1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEVSSSTSWELPLVAVCQVTSTPNKQENFKTCAELVLEAARLGACLAFLPEAFDFIARNPAETLQLSEPLDGDLLGRYSQLARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNNKGLVVATYRKTHLCDVEIPGQGPMRESNSTMPGTILEPPISTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRTSYGHSMVVDPWGTVVASCSEGPGLCLARIDLNFLQQIRQHLPVFQHRRPDLYGNLGQPLS", "length": 292 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P47016-1", "protein_name": "Deaminated glutathione amidase", "gene_name": "NIT2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTSKLKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH", "length": 307 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q557J5-1", "protein_name": "Deaminated glutathione amidase", "gene_name": "nit1-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRNSKILMNKLKRIGLGQITSTNNKEDNFRKCKEMIEKAVENKVNLFCLPECFAFISGGIHQFESRDNAEYLDQKGGIIERYKDLAKQNNIWLSLGGFHEKILDDPNDMIYNTHLIIDSNGVIVCEYRKMHLFDVDIPSKGVKMNESKVVKGGNDLVVCDSPVGKLGLSICYDLRFPELYLSLRRMDAQILLVPSAFMKSTGEAHWKPLLQARAIENQTYVIAAAQTGDHHSKRSSYGHSMIIDPWGKVLHDLPDNLNDIAFVDIDLDYISTCRENIPVFNHKKLNNYKI", "length": 291 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7TQ94-1", "protein_name": "Deaminated glutathione amidase", "gene_name": "Nit1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGFITRPPHQLLSLLCTGYRLPQISVLCTQPRPRAMAESSSTSWELPLVAVCQVTSTPNKQENFKTCAELVQEATRLGACLAFLPEAFDFIARNPAETLLLSEPLDGDLLGQYSQLARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTMPGYALEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVASCSEGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYGSLLPLS", "length": 327 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86X76-1", "protein_name": "Deaminated glutathione amidase", "gene_name": "NIT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAMAISSSSCELPLVAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLNYLRQLRRHLPVFQHRRPDLYGNLGHPLS", "length": 327 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDK1-1", "protein_name": "Deaminated glutathione amidase", "gene_name": "Nit1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGFITRPPHQLLCTGYRLLRTPVLCTQPRPRTMSSSTSWELPLVAVCQVTSTPNKQENFKTCAELVQEAARLGACLAFLPEAFDFIARNPAETLLLSEPLNGDLLGQYSQLARECGIWLSLGGFHERGQDWEQNQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTKPGGTLEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYGSLGHPLS", "length": 323 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94JV5-1", "protein_name": "Deaminated glutathione amidase, chloroplastic/cytosolic", "gene_name": "NLP2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNAYSVSLDFTKPSLFTRITLSSQIPLTMATTVNKTVRVAAAQMTSVNDLMTNFATCSRLVQEAALAGAKLICFPENFSFVGDKEGESVKIAEPLDGPVMERYCSLARDSNIWLSLGGFQERFDDTHLCNTHVVIDDAGMIRDTYQKMHLFDVDVPGGSSYKESSFTVPGTKIVSVDSPVGRLGLTVCYDLRFPKIYQQLRFEQKAQVLLVPSAFTKVTGEAHWEILLRARAIETQCYVIAAAQAGKHNEKRESYGDTLIIDPWGTVVGRLPDRVSTGIVVADIDFSLIDSVRTKMPIDKQRVSIDL", "length": 307 }, "evidence": [ { "id": "A0A8V1AH26", "url": "https://omabrowser.org/oma/group/A0A8V1AH26/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "deaminated glutathione amidase activity", "id": "GO:0110050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AH26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH26" }, { "id": "PS50263", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50263" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CN hydrolase", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 315, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.128", "ec_name": "N-(4-oxoglutaryl)-L-cysteinylglycine + H2O = L-cysteinylglycine + 2-oxoglutarate.", "evidence": [ { "id": "3.5.1.128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.128" }, { "id": "3.5.1.128", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.128" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AH28-1", "uniprot_ac": "A0A8V1AH28", "uniprot_id": "A0A8V1AH28_CHICK", "mass": { "chemical_mass": 108263.0, "monoisotopic_mass": 108263.0 }, "refseq": { "ac": "XP_040509666", "name": "F-BAR domain only protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509666" }, "gene_names": [ { "name": "LOC101748987", "type": "recommended", "evidence": [ { "id": "A0A8V1AH28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ] }, { "name": "LOC101748987", "type": "synonym", "evidence": [ { "id": "XP_040509666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509666" } ] } ], "protein_names": [ { "name": "F-BAR domain only protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040509666", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509666" } ] }, { "name": "FCH and mu domain containing endocytic adaptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AH28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509666", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509666" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101748987", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28", "locus": {} } ], "crossref": [ { "id": "A0A8V1AH28", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH28", "database": "AlphaFoldDB", "categories": [] }, { "id": "101748987", "url": "https://www.ncbi.nlm.nih.gov/gene/101748987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TDSAVMD", "url": "https://omabrowser.org/oma/group/TDSAVMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF25", "url": "https://www.orthodb.org/?gene=A0A8V1AF25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH28", "url": "https://www.orthodb.org/?gene=A0A8V1AH28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040509666", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509666", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFFAEHFWGEKNHGFDVLYHNMKHGQTSTKELADFVRERAAIEESYAKAMVKLSKMATNGTQLGTFAPLWEVFRVSSDKLALCHLELVRKLQELLRELSRYGEEQGRAHKKCKEEAAGTLEAVQLLQGVAQLLAKCKESYHSKCHEHERLRREGTNQKDIDKAELKSQKAAEALRRAVDKYNTARNDFEQRMVESATRFQEVEEAHLRHMKGLIGSYSHSVEDTHVQIGQVHEEFKQNVENIGTETLLRRFAESKGTGRERPGTLDFEEYRLAPAQEGPKRSRSKAFRIPGLSRKERERDAGESPDTDAACPEVDEDGFSVRPDIAHTEAERHSCSSSDSDYDEDEPRRFHVHIKPVQPREGGGSAGATVEQLRATVGTFILPPGVGGTVRRQSSRHTAALSAAPSAADPGGPQVPGDSMGRGHAVAQASSGPGKVPVDAVPPAALFGPPLESAFEAEDFPAPRSYVLTSSSSPFSSSSPENVEDSGLDSPSHPAPVPSPDSRPWTPSAPQSPLPKGGALPDPSPAPPSAWAPPRPRSPGGRLPELPGFAVFPGAEGLWEEGDGGGAGSRGRPRGTAPPPQPPSPDPFGEPWVRPRSPPEERPPQPRPSSNSASSSSSSPAPPSGGESSSPSPWTCPGLGTRTSEGGTAAAPPESAARPPAAAPREVPLVAPPRRSRTKRPAAGPAAGSNSDLSRSLSPPPSWSCPSHSAPASLGERGFFSVCPPPLGLSRGPSPVVLGSQDALPVATAFTEYVHAYFKGRDADSCLVKVTGELTMSFPAGIVRVFSGTMAPPVLSFRLLNAGAIEQFLPNAELLYSDPSQSDPSTRDFWLNMAALTGQLQKQAEQSPSASYYNVALLKYQFSRLGPDSAPLRLCVRWDCTPGATRVSVEYGYNAGALALPVPLANVHVLLPLDEPVTNVRLQPKASWNLEEKRLLWKLLDVPSAPGQGGCGRLSASWQPLGGPSKPSPVAAQFSSEGSTLSGVEVELAGAGYRMSLVKKRFATGIYLAGS", "length": 1012, "header": "tr|A0A8V1AH28-1|A0A8V1AH28_CHICK Isoform 1 of FCH and mu domain containing endocytic adaptor 1 OS=Gallus gallus OX=9031 GN=LOC101748987 PE=3 SV=1 CANONICAL=A0A8V1AH28-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28/entry#A0A8V1AF25-1", "sequence": { "sequence": "MSFFAEHFWGEKNHGFDVLYHNMKHGQTSTKELADFVRERAAIEESYAKAMVKLSKMATNGTQLGTFAPLWEVFRVSSDKLALCHLELVRKLQELLRELSRYGEEQGRAHKKCKEEAAGTLEAVQLLQGVAQLLAKCKESYHSKCHEHERLRREGTNQKDIDKAELKSQKAAEALRRAVDKYNTARNDFEQRMVESATRFQEVEEAHLRHMKGLIGSYSHSVEDTHVQIGQVHEEFKQNVENIGTETLLRRFAESKGTGRERPGTLDFEEYRLAPAQEGPKRSRSKAFRIPGLSRKERERDAGESPDTDAACPEVDEDGFSVRPDIAHTEAERHSCSSSDSDYDEDEPRRFHVHIKPVQPREGGGSAGATVEQLRATVGTFILPPGVGGTVRRQSSRDSMGRGHAVAQASSGPGKVPVDAVPPAALFGPPLESAFEAEDFPAPRSYVLTSSSSPFSSSSPENVEDSGLDSPSHPAPVPSPDSRPWTPSAPQSPLPKGGALPDPSPAPPSAWAPPRPRSPGGRLPELPGFAVFPGAEGLWEEGDGGGAGSRGRPRGTAPPPQPPSPDPFGEPWVRPRSPPEERPPQPRPSSNSASSSSSSPAPPSGGESSSPSPWTCPGLGTRTSEGGTAAAPPESAARPPAAAPREVPLVAPPRRSRTKRPAAGPAAGSNSDLSRSLSPPPSWSCPSHSAPASLGERGFFSVCPPPLGLSRGPSPVVLGSQDALPVATAFTEYVHAYFKGRDADSCLVKVTGELTMSFPAGIVRVFSGTMAPPVLSFRLLNAGAIEQFLPNAELLYSDPSQSDPSTRDFWLNMAALTGQLQKQAEQSPSASYYNVALLKYQFSRLGPDSAPLRLCVRWDCTPGATRVSVEYGYNAGALALPVPLANVHVLLPLDEPVTNVRLQPKASWNLEEKRLLWKLLDVPSAPGQGGCGRLSASWQPLGGPSKPSPVAAQFSSEGSTLSGVEVELAGAGYRMSLVKKRFATGIYLAGS", "length": 991, "header": "tr|A0A8V1AF25-1|A0A8V1AF25_CHICK Computationally mapped isoform of FCH and mu domain containing endocytic adaptor 1 OS=Gallus gallus OX=9031 GN=LOC101748987 PE=3 SV=1 CANONICAL=A0A8V1AH28-1" }, "locus": { "chromosome": "28", "start_pos": 3767406, "end_pos": 3759930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066882.1", "url": "https://www.ensembl.org/id/ENSGALT00010066882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040915.1", "url": "https://www.ensembl.org/id/ENSGALP00010040915.1" } ] } }, { "isoform_ac": "A0A8V1AH28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28/entry#A0A8V1AH28-1", "sequence": { "sequence": "MSFFAEHFWGEKNHGFDVLYHNMKHGQTSTKELADFVRERAAIEESYAKAMVKLSKMATNGTQLGTFAPLWEVFRVSSDKLALCHLELVRKLQELLRELSRYGEEQGRAHKKCKEEAAGTLEAVQLLQGVAQLLAKCKESYHSKCHEHERLRREGTNQKDIDKAELKSQKAAEALRRAVDKYNTARNDFEQRMVESATRFQEVEEAHLRHMKGLIGSYSHSVEDTHVQIGQVHEEFKQNVENIGTETLLRRFAESKGTGRERPGTLDFEEYRLAPAQEGPKRSRSKAFRIPGLSRKERERDAGESPDTDAACPEVDEDGFSVRPDIAHTEAERHSCSSSDSDYDEDEPRRFHVHIKPVQPREGGGSAGATVEQLRATVGTFILPPGVGGTVRRQSSRHTAALSAAPSAADPGGPQVPGDSMGRGHAVAQASSGPGKVPVDAVPPAALFGPPLESAFEAEDFPAPRSYVLTSSSSPFSSSSPENVEDSGLDSPSHPAPVPSPDSRPWTPSAPQSPLPKGGALPDPSPAPPSAWAPPRPRSPGGRLPELPGFAVFPGAEGLWEEGDGGGAGSRGRPRGTAPPPQPPSPDPFGEPWVRPRSPPEERPPQPRPSSNSASSSSSSPAPPSGGESSSPSPWTCPGLGTRTSEGGTAAAPPESAARPPAAAPREVPLVAPPRRSRTKRPAAGPAAGSNSDLSRSLSPPPSWSCPSHSAPASLGERGFFSVCPPPLGLSRGPSPVVLGSQDALPVATAFTEYVHAYFKGRDADSCLVKVTGELTMSFPAGIVRVFSGTMAPPVLSFRLLNAGAIEQFLPNAELLYSDPSQSDPSTRDFWLNMAALTGQLQKQAEQSPSASYYNVALLKYQFSRLGPDSAPLRLCVRWDCTPGATRVSVEYGYNAGALALPVPLANVHVLLPLDEPVTNVRLQPKASWNLEEKRLLWKLLDVPSAPGQGGCGRLSASWQPLGGPSKPSPVAAQFSSEGSTLSGVEVELAGAGYRMSLVKKRFATGIYLAGS", "length": 1012, "header": "tr|A0A8V1AH28-1|A0A8V1AH28_CHICK Isoform 1 of FCH and mu domain containing endocytic adaptor 1 OS=Gallus gallus OX=9031 GN=LOC101748987 PE=3 SV=1 CANONICAL=A0A8V1AH28-1" }, "locus": { "chromosome": "28", "start_pos": 3767406, "end_pos": 3759930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066877.1", "url": "https://www.ensembl.org/id/ENSGALT00010066877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040913.1", "url": "https://www.ensembl.org/id/ENSGALP00010040913.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F8S9-1", "protein_name": "F-BAR domain only protein 1 isoform X1", "gene_name": "Fcho1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYFGEHFWGDKNHGFEVLYHCVKQGPVATKELADFIRERASIEETYSKAMAKLSKMASNGTPMGKDSYAPGCQMHWTLPVPRTFAPLWEVFRVSSDKLALCHLELTRKLHDLLKEVLRYGEEQLKAHKKCKEEVLGTVDAVQVLASVGQLLPKSRENYLSRCMDLERLRRENTSQKEMDKAETKSKKAADSLRRSVDKYNSARADFETKMLDSALRFQAMEESHLQHMKALLGSYAHSVEDTHVQIGQVHEEFKQNVENVTVDMLLRKFAESKGTGCEKPGPLDFDAYSTAALQEAMKRLRGAKAFRLPGLSRREPRAAVDFLESDSGVPPEVDEEGFTVRPDVSHNSMAEPPRFSSSDSDFDDEEPRKFYVHIKPAPTRTVTCSSEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTSGKPQRPRSAPRTGSCAEKPLASEELLSKNLFGPPLESAFDHEDFTGRGGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPESWVPRPGTPQSPPACRTQHPEARGPTPRAPSPGPWGPEAGADSTTREGLAAPPRRPRSRKVSCPLTRSNGDLGRSLSPSPLGLSAPSITSDRPSFSTQMGHGISRGPSPVVLGSQDTLPVATAFTEYVHAYFRGHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTAPVEHFQPNTDLIFSDPSQSDPETKDFWLNMSALTEALQHQAEQNPTASYYNLVLLRYQFSRPGPESVPLQMSAHWQCGPTLTRVTVEYSYRAGATAVSTPLTNVQILLPVGEPVTSVRLQPAASWNTEEKRFTWKLPDVCEAGGSGRLSASWQPQTGPSTPSPVAAQFTSEGATLSGLDLELLGGGYRMSLVKRRFATGMYLASC", "length": 889 }, "evidence": [ { "id": "A0A8V1AH28", "url": "https://omabrowser.org/oma/group/A0A8V1AH28/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZIM5-1", "protein_name": "FCH and mu domain containing endocytic adaptor 1", "gene_name": "Fcho1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYFGEHFWGDKNHGFEVLYHCVKQGPVATKELADFIRERASIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLHDLLKDVLRYGEEQLKTHKKCKEEVQGTVDAVQMLAGVGQLLPKSRENYLSRCMDLERLRRENTSQKEMDKAETKSKKAADSLRRSVDKYNSARADFEIKMLDSALRFQAMEEAHLQHMKTLLGSYAHSVEDTHVQIGQVHEEFKQNVENVTVDMLLRKFAESKGTGREKPGPLDFDAYSSAALQEGNYPLLSTAMKRLRGAKAFRLPGLSRREPRASVDFPESGSGVPPEVDEEGFTVRPDTSQNSEAEPPRFSSSDSDFDDEEPRKFYVRIKPAPARTMACSSEAAAAQLRATAGSLILPPGPGGTMKRLSSRDTSGKPQRPRSAPRSSCTEKPLASEEPLSKSLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSLAAPGPSPESWVPRPGTPQSPPTCRAQHQEARDPVPRVPSPGPWGPEAGAGADSLTLADPTREGLAATLRRPRSRKVSCPLTRSSGDLCRSLSPSPLGSSAPTIPPDRPSFSAQMGHGVSRGPSPVVLGSQDTLPVATAFTEYVYAFFRGHNPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTSPIEHLQPNADLIFSDPSQSDPETKDFWLNMAALTEALQHQAEQNPTASYYNLVLLRYQFSRPGPKSMPLQMSAHWQCGPTLTRVSVEYSYRAGATAVSTPLTNVQILLPVGEPVTSVRLQPAATWNTEEKRFTWKLPDVREAGGSGHLSASWQPQSGPSTPSPVTAQFTSEGATLSGLDLELLGGGYRMSLVKRRFTGMYLTSC", "length": 881 }, "evidence": [ { "id": "A0A8V1AH28", "url": "https://omabrowser.org/oma/group/A0A8V1AH28/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14526-1", "protein_name": "F-BAR domain only protein 1", "gene_name": "FCHO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC", "length": 889 }, "evidence": [ { "id": "A0A8V1AH28", "url": "https://omabrowser.org/oma/group/A0A8V1AH28/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH28", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH28" } ], "pmid": "" }, { "name": "clathrin coat assembly", "id": "GO:0048268", "url": 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"type": "recommended", "evidence": [ { "id": "A0A8V1AH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH43/entry#names_and_taxonomy" } ] }, { "name": "START domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH43/entry#names_and_taxonomy" } ] }, { "name": "StAR-related lipid transfer protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH43/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylcholine transfer protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415652" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415652.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415652" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCTP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH43", "locus": { "chromosome": "18", "start_pos": 6663140, "end_pos": 6654707, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029268", "url": "https://www.ensembl.org/id/ENSGALG00010029268" } ] } } ], "crossref": [ { "id": "A0A8V1AH43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH43", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08910", "url": 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Pathway" ] }, { "id": "DYVYMRE", "url": "https://omabrowser.org/oma/group/DYVYMRE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH43", "url": "https://www.orthodb.org/?gene=A0A8V1AH43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMW5", "url": "https://www.orthodb.org/?gene=A0A8V1AMW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19308:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19308:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483191", "url": 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"MEAPPRRGFSEEQFRAACSELGQTAPGPPWQLLVESMGVSIYRLYDEQSGLYEYKIFGGLADCPPKLCADVYMDLEYRKQWDQYVKELYEKTYDGEKIIYWEVKYPFPLSNRDYVYIRECQEMDVDGRKIWVALAQSVSVPQCPEKPGIIRVKSYKQSLAIESDGKTGSKVYMYYFDNPGGMIPSWLVNWAAKSGVPAFLKDMQKACCNYSKRA", "length": 214, "header": "tr|A0A8V1AH43-1|A0A8V1AH43_CHICK Isoform 1 of Phosphatidylcholine transfer protein OS=Gallus gallus OX=9031 GN=PCTP PE=1 SV=1 CANONICAL=A0A8V1AH43-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH43/entry#A0A8V1AH43-1", "sequence": { "sequence": "MEAPPRRGFSEEQFRAACSELGQTAPGPPWQLLVESMGVSIYRLYDEQSGLYEYKIFGGLADCPPKLCADVYMDLEYRKQWDQYVKELYEKTYDGEKIIYWEVKYPFPLSNRDYVYIRECQEMDVDGRKIWVALAQSVSVPQCPEKPGIIRVKSYKQSLAIESDGKTGSKVYMYYFDNPGGMIPSWLVNWAAKSGVPAFLKDMQKACCNYSKRA", "length": 214, "header": "tr|A0A8V1AH43-1|A0A8V1AH43_CHICK Isoform 1 of Phosphatidylcholine transfer protein OS=Gallus gallus OX=9031 GN=PCTP PE=1 SV=1 CANONICAL=A0A8V1AH43-1" }, "locus": { "chromosome": "18", "start_pos": 6661971, "end_pos": 6654773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070774.1", "url": "https://www.ensembl.org/id/ENSGALT00010070774.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043465.1", "url": "https://www.ensembl.org/id/ENSGALP00010043465.1" } ] } }, { "isoform_ac": "A0A8V1AMW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH43/entry#A0A8V1AMW5-1", "sequence": { "sequence": "MEAPPRELGQTAPGPPWQLLVESMGVSIYRLYDEQSGLYEYKIFGGLADCPPKLCADVYMDLEYRKQWDQYVKELYEKTYDGEKIIYWEVKYPFPLSNRDYVYIRECQEMDVDGRKIWVALAQSVSVPQCPEKPGIIRVKSYKQSLAIESDGKTGSKVYMYYFDNPGGMIPSWLVNWAAKSGVPAFLKDMQKACCNYSKRA", "length": 201, "header": "tr|A0A8V1AMW5-1|A0A8V1AMW5_CHICK Computationally mapped isoform of Phosphatidylcholine transfer protein OS=Gallus gallus OX=9031 GN=PCTP PE=1 SV=1 CANONICAL=A0A8V1AH43-1" }, "locus": { "chromosome": "18", "start_pos": 6661971, "end_pos": 6654773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070773.1", "url": "https://www.ensembl.org/id/ENSGALT00010070773.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043464.1", "url": "https://www.ensembl.org/id/ENSGALP00010043464.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417399", "resource": "KEGG Pathway" }, { "id": "R-GGA-1483191", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483191", "resource": "Reactome", "description": "Synthesis of PC" }, { "id": "R-GGA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "P02720-1", "protein_name": "Phosphatidylcholine transfer protein", "gene_name": "PCTP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPGAGAFSEEQFREACAELQRPALSGAAWELLVETQGISVYRLLDQQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKVFMYYFDNPGGQIPSWVINWAAKNGVPNFLKDMVKACQNYKKT", "length": 213 }, "evidence": [ { "id": "A0A8V1AH43", "url": "https://omabrowser.org/oma/group/A0A8V1AH43/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P53808-1", "protein_name": "Phosphatidylcholine transfer protein", "gene_name": "Pctp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAACCFSDEQFREACAELQKPALTGADWQLLVEASGITIYRLLDQPSGLYEYKVFGVLEGCSPALLTDVYMDLDYRKQWDQYVKELYEKESDEQMVAYWEVKYPFPLSNRDYVYTRQRRDLDVDRRKIYVVLAQSISAPQFPEKSGVIRVKQYKQSLAIESDGKKGSRVFMYYFDNPGGQIPSWLINWAAKNGVPNFLKDMVKACQNYHKKT", "length": 214 }, "evidence": [ { "id": "A0A8V1AH43", "url": "https://omabrowser.org/oma/group/A0A8V1AH43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { 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[ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046757761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757761" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC427783", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45", "locus": {} } ], "crossref": [ { "id": "A0A8V1AH45", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH45", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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{ "id": "A0A8V1AH45", "url": "https://www.orthodb.org/?gene=A0A8V1AH45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIY0", "url": "https://www.orthodb.org/?gene=A0A8V1AIY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46485", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46485", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46485:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46485:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046757761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757761", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AH45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSTGASSGVFSPAIAAHELGWSTRAAVGSARNALHFSCCPAMCEAGLLAPEPSGVARHYGESSDTCCHMDRWQRLRTAVRRLEFWESFSAELVGSGFFSKVYKVTQAAACKVMVVKIYKNDVDQEVIVREISLLQKLSHPNIVRYLGICVKDDKLYPILEYVNGGCLEELLASKDIALSWKEKVDLASDITRGMIYLHSKNIYHRDLNSKNCLIRVTPRGREALVADFGLAREVVELPVQYAERKLSLVGSAFWMAPEMLRGEPYDRKVDVFSFGIVLCEILGRIPADPEVLPRTQDYGLDVAAFCRMVSGCPRQVLDLAACCCRVEAFKRPYFSDILDELEDISENLEPRRDNPLSS", "length": 359, "header": "tr|A0A8V1AH45-1|A0A8V1AH45_CHICK Isoform 1 of Protein kinase domain-containing protein OS=Gallus gallus OX=9031 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"GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AH45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH45" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 349, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AH48-1", "uniprot_ac": "A0A8V1AH48", "uniprot_id": "A0A8V1AH48_CHICK", "mass": { "chemical_mass": 50816.0, "monoisotopic_mass": 50816.0 }, "refseq": { "ac": "XP_040541914", "name": "fibrinogen C domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040541914" }, "gene_names": [ { "name": "FCN3", "type": "recommended", "evidence": [ { "id": "A0A8V1AH48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" } ] }, { "name": "FCN3", "type": "synonym", "evidence": [ { "id": "XP_040541914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040541914" } ] } ], "protein_names": [ { "name": "Ficolin 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AH48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48/entry#names_and_taxonomy" } ] }, { "name": "fibrinogen C domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_040541914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040541914" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052589.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040541914.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040541914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040541914" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FCN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48", "locus": {} } ], "crossref": [ { "id": "A0A8V1AH48", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH48", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427762", "url": "https://www.ncbi.nlm.nih.gov/gene/427762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427762", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVNERWK", "url": "https://omabrowser.org/oma/group/MVNERWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH48", "url": "https://www.orthodb.org/?gene=A0A8V1AH48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040541914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040541914", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNERWKTMGGASQLEDGQQEKPQRMSCGYVLCTVLLSVAVLLAVTVTGAILFMNHYHTPVTEPPPVISTNPEEANALVTIEKADSSRINIFIDPNCPDPAGNVGRLEGLQGSLLRALAEHDAEAKATKGQQKALLLGVADEVAKLVTHAAQLRADCDGLKKGHSAMGQELSALQSEQGRLIQLLSESQTNMARLVSSVSDVLDTLQKERGGVRPRLKADLQRAPARGARPRGCSNGSRPRDCFDIYASGQQEDGIYSIFPTHYPSGFQVYCDMTTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHVLTVQGSYELRVDLEDFDNGTAFAHYGSFGVGLFSVDPEEDGYPISISDYSGTAGDSFLKHNGMKFTTKDLDNDHSENNCAAFYHGAWWYRNCHTSNLNGQYLKGHHSSYADGIEWSSWTGWQYSLKFTEMKIRPVREEN", "length": 460, "header": "tr|A0A8V1AH48-1|A0A8V1AH48_CHICK Isoform 1 of Ficolin 3 OS=Gallus gallus OX=9031 GN=FCN3 PE=4 SV=1 CANONICAL=A0A8V1AH48-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48/entry#A0A8V1AH48-1", "sequence": { "sequence": "MGNERWKTMGGASQLEDGQQEKPQRMSCGYVLCTVLLSVAVLLAVTVTGAILFMNHYHTPVTEPPPVISTNPEEANALVTIEKADSSRINIFIDPNCPDPAGNVGRLEGLQGSLLRALAEHDAEAKATKGQQKALLLGVADEVAKLVTHAAQLRADCDGLKKGHSAMGQELSALQSEQGRLIQLLSESQTNMARLVSSVSDVLDTLQKERGGVRPRLKADLQRAPARGARPRGCSNGSRPRDCFDIYASGQQEDGIYSIFPTHYPSGFQVYCDMTTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHVLTVQGSYELRVDLEDFDNGTAFAHYGSFGVGLFSVDPEEDGYPISISDYSGTAGDSFLKHNGMKFTTKDLDNDHSENNCAAFYHGAWWYRNCHTSNLNGQYLKGHHSSYADGIEWSSWTGWQYSLKFTEMKIRPVREEN", "length": 460, "header": "tr|A0A8V1AH48-1|A0A8V1AH48_CHICK Isoform 1 of Ficolin 3 OS=Gallus gallus OX=9031 GN=FCN3 PE=4 SV=1 CANONICAL=A0A8V1AH48-1" }, "locus": { "chromosome": "17", "start_pos": 6660847, "end_pos": 6650248, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066928.1", "url": "https://www.ensembl.org/id/ENSGALT00010066928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040940.1", "url": "https://www.ensembl.org/id/ENSGALP00010040940.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427762", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AV25-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "Fibcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 459 }, "evidence": [ { "id": "A0A8V1AH48", "url": "https://omabrowser.org/oma/group/A0A8V1AH48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ADA1-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "Fibcd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHERWKTVGGASQLEDRPRDKPQRAGCSYILCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAPPPIVSTGAAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRTLSEHQAQPRLDGAPELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGPHASYADGVEWSSWTGWQYSLKFSEMKIRPLREDR", "length": 459 }, "evidence": [ { "id": "A0A8V1AH48", "url": "https://omabrowser.org/oma/group/A0A8V1AH48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BDM4-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "FIBCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVNDRWKTMGGASQLEDRPRDKPQRPSCSYVLCTVLLSLAVLLAVAVTGAVLLLNHARVPGTAPPPVVSTGPAGANSALVTVDRADSSRLSILIDPRCPDLADGFARLEGAQASVLQALSQRQAELRLPGEQEQELLDTLADQLPRLLARASELQAECSGLRKGHGALGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDVLDALQRDRGLARPHVKADLQRAPARGSRPRGCANGSRPRDCLDVLLSGQQEDGVYSVFPTHDPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMKFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "A0A8V1AH48", "url": "https://omabrowser.org/oma/group/A0A8V1AH48/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S0X3-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "FIBCD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNDRWKTMGGASQLEDRPRDKPQRPSCGYVLCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAPPPIVSTGPAGANSALVTVDRADSSRLSILIDPRCPDLTDGFARLEGAQASVLQALSQRQAEPRLVGEQEQELLDTLADQLPRLLARASELQTECAGLRKGHSTLGQGLSSLQSEQGRLIQLLSESQGHMVHLVNSVSDVLDALQRDRGLGRPHVKADLQRAPARGSRPRGCANGSRPRDCLDVLLSGQQEDGVYSVFPTHDPAGFQVYCDMSTDGGGWTVFQRREDGSVNFFRGWEAYRDGFGKLTGEHWLGLKRLHALTTQAAYELHVDLEDFDNGTAYAHYRSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "A0A8V1AH48", "url": "https://omabrowser.org/oma/group/A0A8V1AH48/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8N539-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "FIBCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "A0A8V1AH48", "url": "https://omabrowser.org/oma/group/A0A8V1AH48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AH48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH48" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 457, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"end_pos": 1194727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066967.1", "url": "https://www.ensembl.org/id/ENSGALT00010066967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040955.1", "url": "https://www.ensembl.org/id/ENSGALP00010040955.1" } ] } }, { "isoform_ac": "A0A8V1AH64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH64/entry#A0A8V1AH64-1", "sequence": { "sequence": "MWQRCQSSVLIGIPNYPTKGSTYLASTCLTEEGAEQPTKHIHLTQQHCGVCSSQIGTVAAVFTVQLLLAFFGMKAWAQKDLQHVEGVSGGVAYLIPRTQGSFYKVEWRFGRDLKIAIHENGEKVNYPNGPYKNRLKLFPNNTLRVDHLRKNDSNTYWVYMEDGAGTEHPEGIVLQVYDAVPKPTVNYVVEDSKPGSCKVTLNCSVALENVTYEWLPPERVTSNGGELSVSFNPLVEVYTCVVRNRVSMNRSQLIYKHPCSWEAESAAPTASIKTSLLVSLGCLLLLLLLTPP", "length": 292, "header": "tr|A0A8V1AH64-1|A0A8V1AH64_CHICK Isoform 1 of CD48 molecule OS=Gallus gallus OX=9031 GN=CD48 PE=4 SV=1 CANONICAL=A0A8V1AH64-1" }, "locus": { "chromosome": "25", "start_pos": 1196216, "end_pos": 1194387, "strand": "-", "evidence": [ { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66/entry#names_and_taxonomy" } ] }, { "name": "Kynurenine aminotransferase I", "type": "synonym", "evidence": [ { "id": "A0A8V1AH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66/entry#names_and_taxonomy" } ] }, { "name": "kynurenine--oxoglutarate transaminase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135057" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135057" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KYAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66", "locus": { "chromosome": "17", "start_pos": 5959716, "end_pos": 5968908, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028582", "url": "https://www.ensembl.org/id/ENSGALG00010028582" } ] } } ], "crossref": [ { "id": "A0A8V1AH66", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH66", "database": 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"R-GGA-71240", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71240", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8964208", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964208", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8964539", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964539", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015135057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135057", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17593", "url": "https://www.rhea-db.org/rhea/17593", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18121", "url": "https://www.rhea-db.org/rhea/18121", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "65560", "url": "https://www.rhea-db.org/rhea/65560", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRVGPFLRHFLLERNCSAGYSSYCSEAKMSRPVQARRLEGVDKNIWVEFVKLAATYSTVNLGQGFPDFPPPEFLKEAFSRAVSGEEEHMLHQYTRAFGHPPLVKILAQLFGKLLGRDLDPMTNVMVTVGAYQALFCCFQAFIDEGDEVIIIEPFFDCYEPMVKMAGGTPVYIPLRPKAPKEGKLMSSADWQLDPAELASKFSEQTKAIVLNSPNNPLGKVFSRGELELIADLCVKHDALCISDEVYEWLVYDGKQHIRIASLPGMWDRTVIIGSAGKTFSVTGWKVGWTVGPNRLLQHLRTVHQNSVYHCATAAQDAVAKGFQRELEHYGKPDSYFVQLPRELQQKRDQLVQSLVAVGMKPIIPEGTYFLVADISEFKSEVPDVPNSDEPYDSRFAKWMVKNKGLAAIPLSAFYCGAHKDNYNTFIRFCFAKEDATLKAADDILQRWKLEKTAP", "length": 456, "header": "tr|A0A8V1AH66-1|A0A8V1AH66_CHICK Isoform 1 of Kynurenine--oxoglutarate transaminase 1 OS=Gallus gallus OX=9031 GN=KYAT1 PE=1 SV=1 CANONICAL=A0A8V1AH66-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66/entry#A0A8V1AH66-1", "sequence": { "sequence": "MLRRVGPFLRHFLLERNCSAGYSSYCSEAKMSRPVQARRLEGVDKNIWVEFVKLAATYSTVNLGQGFPDFPPPEFLKEAFSRAVSGEEEHMLHQYTRAFGHPPLVKILAQLFGKLLGRDLDPMTNVMVTVGAYQALFCCFQAFIDEGDEVIIIEPFFDCYEPMVKMAGGTPVYIPLRPKAPKEGKLMSSADWQLDPAELASKFSEQTKAIVLNSPNNPLGKVFSRGELELIADLCVKHDALCISDEVYEWLVYDGKQHIRIASLPGMWDRTVIIGSAGKTFSVTGWKVGWTVGPNRLLQHLRTVHQNSVYHCATAAQDAVAKGFQRELEHYGKPDSYFVQLPRELQQKRDQLVQSLVAVGMKPIIPEGTYFLVADISEFKSEVPDVPNSDEPYDSRFAKWMVKNKGLAAIPLSAFYCGAHKDNYNTFIRFCFAKEDATLKAADDILQRWKLEKTAP", "length": 456, "header": "tr|A0A8V1AH66-1|A0A8V1AH66_CHICK Isoform 1 of Kynurenine--oxoglutarate transaminase 1 OS=Gallus gallus OX=9031 GN=KYAT1 PE=1 SV=1 CANONICAL=A0A8V1AH66-1" }, "locus": { "chromosome": "17", "start_pos": 5967187, "end_pos": 5960503, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069219.1", "url": "https://www.ensembl.org/id/ENSGALT00010069219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042661.1", "url": "https://www.ensembl.org/id/ENSGALP00010042661.1" } ] } }, { "isoform_ac": "A0A8V1AJE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66/entry#A0A8V1AJE3-1", "sequence": { "sequence": "MLRRVGPFLRHFLLERNCSAGYSSYCSEAKMSRPVQARRLEGVDKNIWVEFVKLAATYSTVNLGQGFPDFPPPEFLKEAFSRAVSGEEEHMLHQYTRAFGHPPLVKILAQLFGKLLGRDLDPMTNVMVTVGAYQALFCCFQAFIDEGDEVIIIEPFFDCYEPMVKMAGGTPVYIPLRPKAPKEGKLMSSADWQLDPAELASKFSEQTKAIVLNSPNNPLGKVFSRGELELIADLCVKHDALCISDEVYEWLVYDGKQHIRIASLPGMWDRTVIIGSAGKTFSVTGWKVGWTVGPNRLLQHLRTVHQNSVYHCATAAQDAVAKGFQRELEHYGKPDSYFVQLPRELQQKRDQLVQSLVAVGMKPIIPEGTYFLVADISEFSEFQCCLGRAEQGGQLSLVLLLGTGTCTNTIQRGEGPHI", "length": 418, "header": "tr|A0A8V1AJE3-1|A0A8V1AJE3_CHICK Computationally mapped isoform of Kynurenine aminotransferase 1 OS=Gallus gallus OX=9031 GN=KYAT1 PE=1 SV=1 CANONICAL=A0A8V1AH66-1" }, "locus": { "chromosome": "17", "start_pos": 5967187, "end_pos": 5961319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069218.1", "url": "https://www.ensembl.org/id/ENSGALT00010069218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042660.1", "url": "https://www.ensembl.org/id/ENSGALP00010042660.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 129, "start_aa": "Thr", "end_pos": 129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr129", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-71240", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71240", "resource": "Reactome", "description": "Tryptophan catabolism" }, { "id": "R-GGA-8964208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964208", "resource": "Reactome", "description": "Phenylalanine metabolism" }, { "id": "R-GGA-8964539", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964539", "resource": "Reactome", "description": "Glutamate and glutamine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TKC4-1", "protein_name": "Kynurenine--oxoglutarate transaminase 1", "gene_name": "KYAT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAERARKRPCGSLTMAKRLQAQRLDGIDYSPRVEFVQLASEEADVVNLGQGFPDFSPPEFAVEAFQHAVSGDFMLNQYTKAFGYPPLTKILANFFGKLLGQEIDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTLMAGGRPVFVSLKPSPTQKGEPDSSSNWQLDPTELASKFTSRTKAFILNTPNNPLGKVFSKEELELVASLCQQHDVVCISDEVYQWMVFDGFQHISIASLPGMWERTLTIGSAGKTFSVTGWKVGWVLGPDSLMKHLRTVHQNSIYHCATQGQAAVAQSFEREQLHFGRPSSYFVQLPQYIQRCRDHMIQSLQSMGFRPVIPQGSYFLITDISDFKNKMPDLPGAAGEPYDRRFVKWMIKNKGLVAVPVSIFFSLPHQKFFDHYIRFCFVKVKDSPGEGRAPQASSDLLGRGVGLICVGAG", "length": 448 }, "evidence": [ { "id": "A0A8V1AH66", "url": "https://omabrowser.org/oma/group/A0A8V1AH66/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QAI8-1", "protein_name": "Kynurenine--oxoglutarate transaminase 1", "gene_name": "kyat1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWRRVAVYGPSLSVRLAIAGFHEKGIMSRRLHARRLEGIDKNIWVEFTQLAADYKAVNLGQGFPDFSPPSFIQEAFCNALTGGFRMHQYTRAFGHPNLVKILAKFFSRIVGREIDPMEDILVSVGAYQALFCTFQALVDEGDEVIIVEPFFDCYQPMVMMAGGMPVYVPLKPREGRGPALTSADWVLSPEELASKFTSRTKAIVINTPNNPLGKVYQWEELQVIADLCIKHDVICISDEVYEWLTYDGAKHVKIASLPGMWERTVTIGSAGKTFSATGWKVGWAIGSGHIMKHLKTVHQNSVYHCATAAQEAISVGFQREYDVFGTEDSYFHQLPITLHEKRKRLADCLKSVGLKPILPQGGYFMIADISNINVDLNDPTTKEEPYDYRFVKWLIKEKGLATIPVSAFYSPEHRDQFQKYIRFCFVKEDSTLQAAENILKQWSENK", "length": 446 }, "evidence": [ { "id": "A0A8V1AH66", "url": "https://omabrowser.org/oma/group/A0A8V1AH66/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3IGZ5-1", "protein_name": "Kynurenine--oxoglutarate transaminase 1", "gene_name": "Kyat1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKQLQARRLNGIDHNPWVEFVRLSKEYDVVNLGQGFPDFSPPDFAVQAFQQATSGDFMLNQYTMAFGYPPLTKILASFFGKLLGQELDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFDCYEPMTLMAGGRPVFVSLRPCPAPKGQLEYSNDWQLDPTELASKFTPRTKALVLNTPNNPLGKVFSKMELELVADLCQQHDVLCISDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSVFHCPTQGQAAVAQCFEREQQHFGQPSSYFLQLPKAMQLNRDHMIRSLQSVGLKPLIPQGSYFLIADISDFKRKMPDLPGVEDEPYDRCFAKWMIKNKGLVAIPVSIFFSQPHQKDFDHYIRFCFVKDEATLQAMDERLQKWKRELHP", "length": 424 }, "evidence": [ { "id": "A0A8V1AH66", "url": "https://omabrowser.org/oma/group/A0A8V1AH66/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q16773-1", "protein_name": "Kynurenine--oxoglutarate transaminase 1", "gene_name": "KYAT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL", "length": 422 }, "evidence": [ { "id": "A0A8V1AH66", "url": "https://omabrowser.org/oma/group/A0A8V1AH66/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BTY1-1", "protein_name": "Kynurenine--oxoglutarate transaminase 1", "gene_name": "Kyat1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKQLQARRLEGIDHNPWVEFTRLSKEYDVVNLGQGFPDFSPPDFAVQAFQQATTGNFMLNQYTSAFGYPPLTKILASFFGKLLGQEMDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLSPAPKGQLGSSNDWQLDPTELASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMGLNRDHMIQSLQSVGLKPLIPQGSYFLIADISDFKSSMPDLPGAMDEPYDTRFAKWMIKNKGLSAIPVSTFYSQPHHKDFDHYIRFCFVKDKATLQAMDKRLCSWKGEPQA", "length": 424 }, "evidence": [ { "id": "A0A8V1AH66", "url": "https://omabrowser.org/oma/group/A0A8V1AH66/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CAP1-1", "protein_name": "Pyridoxal phosphate (PLP)-dependent transferases superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLDINGVMIKQFSFKASLLPFSSNFRQSSAKIHRPIGATMTTVSTQNESTQKPVQVAKRLEKFKTTIFTQMSILAVKHGAINLGQGFPNFDGPDFVKEAAIQAIKDGKNQYARGYGIPQLNSAIAARFREDTGLVVDPEKEVTVTSGCTEAIAAAMLGLINPGDEVILFAPFYDSYEATLSMAGAKVKGITLRPPDFSIPLEELKAAVTNKTRAILMNTPHNPTGKMFTREELETIASLCIENDVLVFSDEVYDKLAFEMDHISIASLPGMYERTVTMNSLGKTFSLTGWKIGWAIAPPHLTWGVRQAHSYLTFATSTPAQWAAVAALKAPESYFKELKRDYNVKKETLVKGLKEVGFTVFPSSGTYFVVADHTPFGMENDVAFCEYLIEEVGVVAIPTSVFYLNPEEGKNLVRFAFCKDEETLRGAIERMKQKLKRKV", "length": 440 }, "evidence": [ { "id": "A0A8V1AH66", "url": "https://omabrowser.org/oma/group/A0A8V1AH66/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "glutamine-phenylpyruvate transaminase activity", "id": "GO:0047316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047316", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" }, { "name": "kynurenine-oxoglutarate transaminase activity", "id": "GO:0016212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" }, { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" }, { "name": "cysteine-S-conjugate beta-lyase activity", "id": "GO:0047804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "kynurenine metabolic process", "id": "GO:0070189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070189", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH66", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17593", "name": "", "equation": "3-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AH66-1" ], "evidence": [ { "id": "17593", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17593" } ] }, { "id": "18121", "name": "", "equation": "an S-substituted L-cysteine + H2O = a thiol + pyruvate + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZT89-1", "A0A8V1AH66-1" ], "evidence": [ { "id": "18121", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18121" } ] }, { "id": "65560", "name": "", "equation": "L-kynurenine + 2-oxoglutarate = kynurenate + L-glutamate + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZT89-1", "A0A8V1AH66-1", "P00508-1", "A0A8V0XTC1-1" ], "evidence": [ { "id": "65560", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65560" } ] }, { "id": "R-GGA-893593", "name": "phenylalanine + pyruvate => keto-phenylpyruvate + alanine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29398", "R-ALL-29502" ], "output_participant_list": [ "R-ALL-29432", "R-ALL-2160487" ], "enzyme_list": [ "A0A8V1AH66-1" ], "evidence": [ { "id": "R-GGA-893593", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-893593" } ] }, { "id": "R-GGA-893596", "name": "PXLP-KYAT1 dimer transaminates L-KYN to KYNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29970" ], "output_participant_list": [ "R-ALL-893587" ], "enzyme_list": [ "A0A8V1AH66-1" ], "evidence": [ { "id": "R-GGA-893596", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-893596" } ] }, { "id": "R-GGA-893616", "name": "glutamine + pyruvate => 2-oxoglutaramate + alanine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-893598" ], "enzyme_list": [ "A0A8V1AH66-1" ], "evidence": [ { "id": "R-GGA-893616", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-893616" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2160487", "participant_name": "kPPV [cytosol]", "crossref": [ { "id": "156-06-9", "database": "CAS", "url": "" }, { "id": "C00166", "database": "COMPOUND", "url": "" }, { "id": "PHENYL-PYRUVATE", "database": "AraCyc", "url": "" }, { "id": "18005", "database": "ChEBI", "url": "" }, { "id": "4592697", "database": "PubChem Compound", "url": "" }, { "id": "ZINC000000901485", "database": "ZINC", "url": "" }, { "id": "C00000751", "database": "KNApSAcK", "url": "" } ] }, { "participant_id": "R-ALL-29398", "participant_name": "PYR [cytosol]", "crossref": [ { "id": "15361", "database": "ChEBI", "url": "" }, { "id": "c0159", "database": "UMBBD", "url": "" }, { "id": "127-17-3", "database": "CAS", "url": "" }, { "id": "PYRUVATE", "database": "AraCyc", "url": "" }, { "id": "C00001200", "database": "KNApSAcK", "url": "" }, { "id": "C00022", "database": "KEGG Gene", "url": "" }, { "id": "c00022", "database": "KEGG Gene", "url": "" }, { "id": "107735", "database": "PubChem Compound", "url": "" }, { "id": "ZINC000001532517", "database": "ZINC", "url": "" }, { "id": "C00022", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-29432", "participant_name": "L-Ala [cytosol]", "crossref": [ { "id": "57972", "database": "ChEBI", "url": "" }, { "id": "C00041", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004658553", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-29502", "participant_name": "L-Phe [cytosol]", "crossref": [ { "id": "58095", "database": "ChEBI", "url": "" }, { "id": "ZINC000000105196", "database": "ZINC", "url": "" }, { "id": "C00079", 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"MWAPEPLTFSLWDYGVFGLMLLISTGIGLFHGLSKGGQKTSEDFFMGGRRMAAVPVGLSLSASFMSAIQVLGVPAEAYRYGSKFLWMCLGQLLNTLLTAYLFLPVFYRLGLTSTYEYLERRFGRSVRLCGTLQYVVATTLYTGIVIYAPALILNQVTGLDIWASLLSTGAICTFYTTIGGMKAVIWTDVFQVFVMLSGFLAVIIRGLLLVGGPSRALAIATNGSRVNLGDFDFDPRSRYTFWTFLLGGTLVWLSMYGVNQAQVQRYVACKSEREARIALLVNQVGLFCIVSSAVACGLVMFVLYKDCDPLLAGHISAPDQYMPYLVLDIFQTSPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLVKPRLPTLSPRRLMLISKGLSLFYGTACITVAALASLLGGGVLQGSFTVMGVIGGPLLGAFVLGMFVPACNTATPLLALQGVFGGLSVGLTLSLWVAVGGSLYPAPANIAGVLPASGAHCPLYNHTASTNHTLLMGPLPPQHPSREPARPPIVGDFYAISYLYYGALGTLSTVLAGVLLSYLAGPTKRAQLPPGVLWWDITKQTSSVSPAGGTAPSGGCPTKVCRDPQGGPCPEAPPVLLARPPPQHRGVTEQLLQESHV", "length": 627, "header": "tr|A0A8V1AH69-1|A0A8V1AH69_CHICK Isoform 1 of Solute carrier family 5 member 5 OS=Gallus gallus OX=9031 GN=SLC5A5 PE=3 SV=1 CANONICAL=A0A8V1AH69-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69/entry#A0A8V1AH69-1", "sequence": { "sequence": "MWAPEPLTFSLWDYGVFGLMLLISTGIGLFHGLSKGGQKTSEDFFMGGRRMAAVPVGLSLSASFMSAIQVLGVPAEAYRYGSKFLWMCLGQLLNTLLTAYLFLPVFYRLGLTSTYEYLERRFGRSVRLCGTLQYVVATTLYTGIVIYAPALILNQVTGLDIWASLLSTGAICTFYTTIGGMKAVIWTDVFQVFVMLSGFLAVIIRGLLLVGGPSRALAIATNGSRVNLGDFDFDPRSRYTFWTFLLGGTLVWLSMYGVNQAQVQRYVACKSEREARIALLVNQVGLFCIVSSAVACGLVMFVLYKDCDPLLAGHISAPDQYMPYLVLDIFQTSPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLVKPRLPTLSPRRLMLISKGLSLFYGTACITVAALASLLGGGVLQGSFTVMGVIGGPLLGAFVLGMFVPACNTATPLLALQGVFGGLSVGLTLSLWVAVGGSLYPAPANIAGVLPASGAHCPLYNHTASTNHTLLMGPLPPQHPSREPARPPIVGDFYAISYLYYGALGTLSTVLAGVLLSYLAGPTKRAQLPPGVLWWDITKQTSSVSPAGGTAPSGGCPTKVCRDPQGGPCPEAPPVLLARPPPQHRGVTEQLLQESHV", "length": 627, "header": "tr|A0A8V1AH69-1|A0A8V1AH69_CHICK Isoform 1 of Solute carrier family 5 member 5 OS=Gallus gallus OX=9031 GN=SLC5A5 PE=3 SV=1 CANONICAL=A0A8V1AH69-1" }, "locus": { "chromosome": "28", "start_pos": 3782915, "end_pos": 3778819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066983.1", "url": "https://www.ensembl.org/id/ENSGALT00010066983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040965.1", "url": "https://www.ensembl.org/id/ENSGALP00010040965.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431544", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431544", "resource": "KEGG Pathway" }, { "id": "R-GGA-209968", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209968", "resource": "Reactome", "description": "Thyroxine biosynthesis" }, { "id": "R-GGA-9958790", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958790", "resource": "Reactome", "description": "SLC-mediated transport of inorganic anions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F7F7-1", "protein_name": "Sodium/iodide cotransporter isoform X1", "gene_name": "Slc5a5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGAQAAARATFGPWDYGVFAVMLLVSTGIGLGVGLARGGQRSAEDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCAGQLLNSLLTAALFLPVFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGVICTLYTTVGGMKAVVWTDVFQVVVMLSGFWVILARGTVLMGGPWNVLSLARNHSRINLMDFDPDPRSRYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTESRAKLALLVNQLGLFLIVVSAACCGIVMFVFYRDCDPLLTERISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPSLAPRKLVLISKGLSLIYGSACLTVAALSSMLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLAAGLIVSLWVAVGATLYPPGEQIMGVLPTSAASCTNASVLMGPPGAANASSRVPSSGTEAGRPALADTFYAISYLYYGALGTLTTLLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDAATLVEDSLVKVRPSLGHWAPGPWGPSGCSPRGWADSSPLLKLPLSQGLTHMSTVYFYRVCFFKELFPACGGENWFPLERETLLKKILKITLVNSELRKKQGELAGAEPGNCRASAPKVGDTVTS", "length": 699 }, "evidence": [ { "id": "A0A8V1AH69", "url": "https://omabrowser.org/oma/group/A0A8V1AH69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q63008-1", "protein_name": "Sodium/iodide cotransporter", "gene_name": "Slc5a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGAEAGARATFGAWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGGTLVWLSMYGVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPGLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLAAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNDSVLLGPPGATNASNGIPSSGMDTGRPALADTFYAISYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTATLEESLVKGPEDIPAVTKKPPGLKPGAETHPLYLGHDVETNL", "length": 618 }, "evidence": [ { "id": "A0A8V1AH69", "url": "https://omabrowser.org/oma/group/A0A8V1AH69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92911-1", "protein_name": "Sodium/iodide cotransporter", "gene_name": "SLC5A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL", "length": 643 }, "evidence": [ { "id": "A0A8V1AH69", "url": "https://omabrowser.org/oma/group/A0A8V1AH69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99PN0-1", "protein_name": "Sodium/iodide cotransporter", "gene_name": "Slc5a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGAEAGARATFGPWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCVGQLLNSLLTALLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVMLMGGPWNVLSLAQNHSRINLMDFDPDPRSRYTFWTFVVGGSLVWLSMYGVNQAQVQRYVACHTERKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRIAAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPSLAPRKLVFISKGLSFIYGSTCLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLTAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNASVLPSPPGAANTSRGIPSSGMDSGRPAFADTFYAVSYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTTTLEDSLVKGPEDIPAATKKPPGFRPEAETHPLYLGHDVETNL", "length": 618 }, "evidence": [ { "id": "A0A8V1AH69", "url": "https://omabrowser.org/oma/group/A0A8V1AH69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "sodium:iodide symporter activity", "id": "GO:0008507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cellular response to cAMP", "id": "GO:0071320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071320", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "cellular response to forskolin", "id": "GO:1904322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904322", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "cellular response to Thyroid stimulating hormone", "id": "GO:1904401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904401", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "cellular response to gonadotropin stimulus", "id": "GO:0071371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" }, { "name": "iodide transmembrane transport", "id": "GO:1904200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "71207", "name": "", "equation": "iodide(out) + 2 Na(+)(out) = iodide(in) + 2 Na(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71207", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71207" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 497, "end_pos": 499 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AH71-1", "uniprot_ac": "A0A8V1AH71", "uniprot_id": "A0A8V1AH71_CHICK", "mass": { "chemical_mass": 29801.0, "monoisotopic_mass": 29801.0 }, "refseq": {}, "gene_names": [ { "name": "ORM1", "type": "recommended", "evidence": [ { "id": "A0A8V1AH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH71" } ] } ], "protein_names": [ { "name": "Orosomucoid 1 (ovoglycoprotein)", "type": "synonym", "evidence": [ { "id": "A0A8V1AH71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH71/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH71", "url": 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"common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH72", "locus": {} } ], "crossref": [ { "id": "A0A8V1AH72", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH72", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13538", "url": 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"MGPKVTGPIVPPVRRMSPVPEELSLVPLHQHPELLEACAELLAEEWGKSRALRLHSLQRSSDAFPTCLALLRAPAPAEPACPHCLVGHIRLSRVAGQPGGLFVESVVVARALRGRGYGRQLMEATERYARTRGFRRLHLSTHDKQQFYAHLGFVPAEPVQIVPFLSPAMPAAALRAFTAPPSPTAATPAVPAAPRPPLPPPAVPPPPPLPPPSRAGGGPAEGGGQSPQESPHRDTRGLPIFWMKKDI", "length": 247, "header": "tr|A0A8V1AH72-1|A0A8V1AH72_CHICK Isoform 1 of N-alpha-acetyltransferase 80, NatH catalytic subunit OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AH72-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH72/entry#A0A8V1AH72-1", "sequence": { "sequence": "MGPKVTGPIVPPVRRMSPVPEELSLVPLHQHPELLEACAELLAEEWGKSRALRLHSLQRSSDAFPTCLALLRAPAPAEPACPHCLVGHIRLSRVAGQPGGLFVESVVVARALRGRGYGRQLMEATERYARTRGFRRLHLSTHDKQQFYAHLGFVPAEPVQIVPFLSPAMPAAALRAFTAPPSPTAATPAVPAAPRPPLPPPAVPPPPPLPPPSRAGGGPAEGGGQSPQESPHRDTRGLPIFWMKKDI", "length": 247, "header": "tr|A0A8V1AH72-1|A0A8V1AH72_CHICK Isoform 1 of N-alpha-acetyltransferase 80, NatH catalytic subunit OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AH72-1" }, "locus": { "chromosome": "12", "start_pos": 3420789, "end_pos": 3419060, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066993.1", "url": "https://www.ensembl.org/id/ENSGALT00010066993.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040970.1", "url": "https://www.ensembl.org/id/ENSGALP00010040970.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 184, "start_aa": "Thr", "end_pos": 184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr184", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", 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"UniProtKB", "id": "A0A8V1AH72", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH72" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 180, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 184, 187 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJF1-1", "uniprot_ac": "A0A8V1AJF1", "uniprot_id": "A0A8V1AJF1_CHICK", "mass": { "chemical_mass": 36670.0, "monoisotopic_mass": 36670.0 }, "refseq": { "ac": "XP_015155591", "name": "BRISC and BRCA1-A complex member 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155591" }, "gene_names": [ { "name": "BABAM1", "type": "recommended", "evidence": [ { "id": "A0A8V1AJF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ] }, { "name": "BABAM1", "type": "synonym", "evidence": [ { "id": "XP_015155591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155591" } ] } ], "protein_names": [ { "name": "BRISC and BRCA1 A complex member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AJF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1/entry#names_and_taxonomy" } ] }, { "name": "BRISC and BRCA1-A complex member 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015155591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155591" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155591" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BABAM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1", "locus": { "chromosome": "28", "start_pos": 3833015, "end_pos": 3826247, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028586", "url": "https://www.ensembl.org/id/ENSGALG00010028586" } ] } } ], "crossref": [ { "id": "A0A8V1AJF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21502", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21502", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "776677", "url": "https://www.ncbi.nlm.nih.gov/gene/776677", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCTTAWP", "url": "https://omabrowser.org/oma/group/SCTTAWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEW2", "url": "https://www.orthodb.org/?gene=A0A8V1AEW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH74", "url": "https://www.orthodb.org/?gene=A0A8V1AH74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJF1", "url": "https://www.orthodb.org/?gene=A0A8V1AJF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15660", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15660", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15660:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15660:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-5689901", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693565", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693565", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693571", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693607", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69473", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69473", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155591", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERSCGMDTSGPGSAAEEEEEKAPEQRPRTRSNPEGAEDRALSAQSSVGNRSEGEGEAASSEDSPQGTAAPDGTAWPGPAHPPPEVQVKTPRVNCPEKVIICLDLAEEMALPKLESFNGSKTNALNISQKMIEMFVRTKHKIDKSHEFALVVVNNDATWLSGFTSDPREVCSCLYDLETVVCKSFNLDGLFNLIQQKIELPVTDNVQTIPPPYVVRTILVLGRPGCQPQFSVSEQMKKMLQCPYFFFDVVYIHNGAEEKEDETSWKELYAFFGSLDTKGTNYRYEVTLTGPAVELHNCMAKLLAHPLQRPFQSHAAYSLLEGDEPPEVEATV", "length": 332, "header": "tr|A0A8V1AJF1-1|A0A8V1AJF1_CHICK Isoform 1 of BRISC and BRCA1 A complex member 1 OS=Gallus gallus OX=9031 GN=BABAM1 PE=4 SV=1 CANONICAL=A0A8V1AJF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1/entry#A0A8V1AEW2-1", "sequence": { "sequence": "MGCAEQRVHEAGGAQSKGCTGSARMGGARSWGCSDPPQPPQSGAMERSCGMDTSGPGSAAEEEEEKAPEQRPRTRSNPEGAEDRALSAQSSVGNRSEGEGEAASSEDSPQGTAAPDGTAWPGPAHPPPEVQVKTPRVNCPEKVIICLDLAEEMALPKLESFNGSKTNALNISQKMIEMFVRTKHKIDKSHEFALVVVNNDATWLSGFTSDPREVCSCLYDLETVVCKSFNLDGLFNLIQQKIELPVTDNVQTIPPPYVVRTILVLGRPGCQPQFSVSEQMKKMLQCPYFFFDVVYIHNGAEEKEDETSWKELYAFFGSLDTKGTNYRYEVTLTGPAVELHNCMAKLLAHPLQRPFQSHAAYSLLEGDEPPEVEATV", "length": 376, "header": "tr|A0A8V1AEW2-1|A0A8V1AEW2_CHICK Computationally mapped isoform of BRISC and BRCA1 A complex member 1 OS=Gallus gallus OX=9031 GN=BABAM1 PE=4 SV=1 CANONICAL=A0A8V1AJF1-1" }, "locus": { "chromosome": "28", "start_pos": 3832924, "end_pos": 3830633, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069227.1", "url": "https://www.ensembl.org/id/ENSGALT00010069227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042669.1", "url": "https://www.ensembl.org/id/ENSGALP00010042669.1" } ] } }, { "isoform_ac": "A0A8V1AH74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1/entry#A0A8V1AH74-1", "sequence": { "sequence": "MQVSPPAACCSRACSRRANACMRCACCCCTAPARASRCCSCAACLRRALRYARARALRAQHHCGPPQSGAMERSCGMDTSGPGSAAEEEEEKAPEQRPRTRSNPEGAEDRALSAQSSVGNRSEGEGEAASSEDSPQGTAAPDGTAWPGPAHPPPEVQVKTPRVNCPEKVIICLDLAEEMALPKLESFNGSKTNALNISQKMIEMFVRTKHKIDKSHEFALVVVNNDATWLSGFTSDPREVCSCLYDLETVVCKSFNLDGLFNLIQQKIELPVTDNVQTIPPPYVVRTILVLGRPGCQPQFSVSEQMKKMLQCPYFFFDVVYIHNGAEEKEDETSWKELYAFFGSLDTKGTNYRYEVTLTGPAVELHNCMAKLLAHPLQRPFQSHAAYSLLEGDEPPEVEATV", "length": 402, "header": "tr|A0A8V1AH74-1|A0A8V1AJF1_CHICK Computationally mapped isoform of BRISC and BRCA1 A complex member 1 OS=Gallus gallus OX=9031 GN=BABAM1 PE=4 SV=1 CANONICAL=A0A8V1AJF1-1" }, "locus": { "chromosome": "28", "start_pos": 3832924, "end_pos": 3826446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069229.1", "url": "https://www.ensembl.org/id/ENSGALT00010069229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042671.1", "url": "https://www.ensembl.org/id/ENSGALP00010042671.1" } ] } }, { "isoform_ac": "A0A8V1AJF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1/entry#A0A8V1AJF1-1", "sequence": { "sequence": "MERSCGMDTSGPGSAAEEEEEKAPEQRPRTRSNPEGAEDRALSAQSSVGNRSEGEGEAASSEDSPQGTAAPDGTAWPGPAHPPPEVQVKTPRVNCPEKVIICLDLAEEMALPKLESFNGSKTNALNISQKMIEMFVRTKHKIDKSHEFALVVVNNDATWLSGFTSDPREVCSCLYDLETVVCKSFNLDGLFNLIQQKIELPVTDNVQTIPPPYVVRTILVLGRPGCQPQFSVSEQMKKMLQCPYFFFDVVYIHNGAEEKEDETSWKELYAFFGSLDTKGTNYRYEVTLTGPAVELHNCMAKLLAHPLQRPFQSHAAYSLLEGDEPPEVEATV", "length": 332, "header": "tr|A0A8V1AJF1-1|A0A8V1AJF1_CHICK Isoform 1 of BRISC and BRCA1 A complex member 1 OS=Gallus gallus OX=9031 GN=BABAM1 PE=4 SV=1 CANONICAL=A0A8V1AJF1-1" }, "locus": { "chromosome": "28", "start_pos": 3832924, "end_pos": 3830976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069228.1", "url": "https://www.ensembl.org/id/ENSGALT00010069228.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042670.1", "url": "https://www.ensembl.org/id/ENSGALP00010042670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" }, { "id": "R-GGA-5693565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693565", "resource": "Reactome", "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" }, { "id": "R-GGA-5693571", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693571", "resource": "Reactome", "description": "Nonhomologous End-Joining (NHEJ)" }, { "id": "R-GGA-5693607", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693607", "resource": "Reactome", "description": "Processing of DNA double-strand break ends" }, { "id": "R-GGA-69473", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69473", "resource": "Reactome", "description": "G2/M DNA damage checkpoint" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQV9-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVVEPSSPTEEEEEEEEEEEQSAEPRPRTRSNPEGAEDRALGAQASVGSRSEGEGEAASADDGTLNPPGAGPKPWQVPPPTPEVQVRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNALNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDVVYIHNGAEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLAHPLQRPCQSHASYSLLEEDDEATEVEATV", "length": 332 }, "evidence": [ { "id": "A0A8V1AJF1", "url": "https://omabrowser.org/oma/group/A0A8V1AJF1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08E57-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVAEPSCPTEEEEEEEEEEEQSAEPRPRTRSNPEGAEDRALGAQTSVGSRSEGEGEAASADDGTANPPGAGPKPWQVPPPAPEVQVRTPRVNCPEKVIICLDLSEEMALPKLESFNGSKTNALNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDVVYIHNGADEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLAHPLQRPCQSHASYSLLEEDDEATEVEATV", "length": 332 }, "evidence": [ { "id": "A0A8V1AJF1", "url": "https://omabrowser.org/oma/group/A0A8V1AJF1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UI43-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "Babam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVAEANSPTEEEEEEEEEGEETISEPRPHTRSNPEGAEDRALGAQASVGSRSEGEGEAATADGGAASVPGAGPKPWQVPASASEVQIRTPRVNCPEKVIICLDLSEEMSVPKLESFNGSRTNALNVSQKMVEMFVRTKHKIDKSHEFALVVVNDDSAWLSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDIVYIHNGTEEKEEDMSWKDMFAFMGSLDTKGASYKYEVALAGPALELHNCMAKLLAHPLQRPCQTHASYSLLEEDEEAGEEEATV", "length": 333 }, "evidence": [ { "id": "A0A8V1AJF1", "url": "https://omabrowser.org/oma/group/A0A8V1AJF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XIJ6-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "Babam1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVAEANSPTEEEEEEEEEEGEEPISEPRPHTRSNPEGAEDRAIGAQANVGSRSEGEGEAATADDGAASVPGAVPKPWQVPAPASEVQIRTPRVNCPEKVIICLDLSEEMSVPKLESFNGSRTNALNVSQKMVEMFVRTKHKIDKSHEFALVVVNDDSAWLSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDIIYIHSGPEEKEDDMSWKDMFAFMGSLDTKGTSYKYAVALAGPALELHNCVAKLLAHPLQRPCQSHASYSLLEEDEEAGEGEATV", "length": 334 }, "evidence": [ { "id": "A0A8V1AJF1", "url": "https://omabrowser.org/oma/group/A0A8V1AJF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AXK4-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "babam1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METTEPGQADGEERMMDLRPRTRSNPEGAEDRRSSTGSLNSSLPSAPQPAVGSRVEGEGEAASSDSPPVSATAIAATASVPVAAVGNTTTTNTASLPAMSPAVKERPKPSQPTMPTQIPPSAELHLRAPRVNCPEKVIICLDLSEEMSLQKLESINGSKTNALNISQKMIEMFVRTKHKIDKRHEFALVVVNDDAMWLSGFTSDPRELCSCLYDLETNVCESFNLEDLFNVILQKIELPQMENIQTIPPPFVVRTLLVFSRHAGMLQFNPSDAVKKMLQSPYFFFDVVFLHNGTEEQTEDTSWKDVYASFCELDTKGMCYRFEVSLCGPAIELHNCMAKLLCHPLQRPFQSHASYSLLEDEDTLENEATV", "length": 370 }, "evidence": [ { "id": "A0A8V1AJF1", "url": "https://omabrowser.org/oma/group/A0A8V1AJF1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADDGSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNALNVSQKMIEMFVRTKHKIDKSHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYVVRTILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKYEVALAGPALELHNCMAKLLAHPLQRPCQSHASYSLLEEEDEAIEVEATV", "length": 329 }, "evidence": [ { "id": "A0A8V1AJF1", "url": "https://omabrowser.org/oma/group/A0A8V1AJF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "BRISC complex", "id": "GO:0070552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "BRCA1-A complex", "id": "GO:0070531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070531", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "positive regulation of DNA repair", "id": "GO:0045739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "DNA repair-dependent chromatin remodeling", "id": "GO:0140861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 126, "end_pos": 128 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AH94-1", "uniprot_ac": "A0A8V1AH94", "uniprot_id": "A0A8V1AH94_CHICK", "mass": { "chemical_mass": 88838.0, "monoisotopic_mass": 88838.0 }, "refseq": { "ac": "XP_414322", "name": "protein tyrosine phosphatase domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414322" }, "gene_names": [ { "name": "PTPDC1", "type": "recommended", "evidence": [ { "id": "A0A8V1AH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94" } ] }, { "name": "PTPDC1", "type": "synonym", "evidence": [ { "id": "XP_414322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414322" } ] } ], "protein_names": [ { "name": "Protein tyrosine phosphatase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94/entry#names_and_taxonomy" } ] }, { "name": "protein tyrosine phosphatase domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_414322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414322" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_414322.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414322" } ] }, { "annotation": "May play roles in cilia formation and/or maintenance.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q3A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A4X3#function" }, { "database": "UniProtKB", "id": "ARBA00056295", "url": "https://www.uniprot.org/uniprotkb/ARBA00056295#function" }, { "database": "UniProtKB", "id": "E1C6I5", "url": "https://www.uniprot.org/uniprotkb/E1C6I5#function" }, { "database": "UniProtKB", "id": "A0A8V1ACN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN4#function" }, { "database": "UniProtKB", "id": "A0A8V1AFA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA4#function" }, { "database": "UniProtKB", "id": "A0A8V1AH94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTPDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94", "locus": { "chromosome": "12", "start_pos": 6285854, "end_pos": 6305537, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027667", "url": "https://www.ensembl.org/id/ENSGALG00010027667" } ] } } ], "crossref": [ { "id": "A0A8V1AH94", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005128", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005128", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415979", "url": "https://www.ncbi.nlm.nih.gov/gene/415979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3A4X3", "url": "https://www.orthodb.org/?gene=A0A3Q3A4X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACN4", "url": "https://www.orthodb.org/?gene=A0A8V1ACN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFA4", "url": "https://www.orthodb.org/?gene=A0A8V1AFA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH94", "url": "https://www.orthodb.org/?gene=A0A8V1AH94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6I5", "url": "https://www.orthodb.org/?gene=E1C6I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414322", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3A4X3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A4X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3A4X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A4X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6I5", "url": "https://www.uniprot.org/uniprotkb/E1C6I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6I5-1", "url": "https://www.uniprot.org/uniprotkb/E1C6I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGSPRRRSAVSIFSNFFQGRRHSSSDPLLRIIQRRRSSVVEVLSSSTHRVMVAISSLSPEELDATFPEKKRSSRRPTAKYTKVGERLRHVIPGHMQCSMACGGRACKYENPARWSDQEQAIKGLYSSWITDNILAMARPSTELIEKYNIIEQFEKCGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMAFALQEGRVAVHCHAGLGRTGVLVACYLVFATRMTADQAILFVRAKRPNSIQTRGQLLCIREFTQFLIPLRNVFACCEPKAHRVTLSQYLTRQRHLLHGYESRHLKHVPKLIHIVCKLLLDLAENRQVVEAELLDIADLSAEIEKTVSQLVSTQLDGDLARQDSDMSDSSHTHSATCDTQDSLFSLAHECDPLWKRRNVECLQPLSHVRRRLSYSDSDLRRTEFLLEQGETAWTVPAQILLCNKLKQNSSEESSATDEQKPQLDLNKEALVRNTCTIWSQTKFNLDGQKDGSSLYQRRNSTKEVQRSRTFSSGLASLHYTREPGTPRHNFTNEVGHRKERETRTYSRRVYVSEDSDSSSSSKVNFSIGCESQGSKDPSEAIPHIVLQSELSLEARRVLAAKALANINEFLEEDEVKQKVEMWQKELNSRDGAWDKISTERDPFILCSLMWSWIEQLKEPIISKDDIDMLAKNSIESQDALNLLRKEQCQTILCILHCVVNLQTLPADVEEALLVRAIKAFTKTSFDSEDGPHVYNTLKKVFKQTLEEKRKKLKEGTENPS", "length": 781, "header": "tr|A0A8V1AH94-1|A0A8V1AH94_CHICK Isoform 1 of Protein tyrosine phosphatase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PTPDC1 PE=3 SV=1 CANONICAL=A0A8V1AH94-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3A4X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94/entry#A0A3Q3A4X3-1", "sequence": { "sequence": "MAAGVLLQNELPYSSLLESSVYLANMSSGSSRRPTAKYTKVGERLRHVIPGHMQCSMACGGRACKYENPARWSDQEQAIKGLYSSWITDNILAMARPSTELIEKYNIIEQFEKCGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMAFALQEGRVAVHCHAGLGRTGVLVACYLVFATRMTADQAILFVRAKRPNSIQTRGQLLCIREFTQFLIPLRNVFACCEPKAHRVTLSQYLTRQRHLLHGYESRHLKHVPKLIHIVCKLLLDLAENRQVVEAELLDIADLSAEIEKTVSQLVSTQLDGDLARQDSDMSDSSHTHSATCDTQDSLFSLAHECDPLWKRRNVECLQPLSHVRRRLSYSDSDLRRTEFLLEQGETAWTVPAQILLCNKLKQNSSEESSATDEQKPQLDLNKEALVRNTCTIWSQTKFNLDGQKDGSSLYQRRNSTKEVQRSRTFSSGLASLHYTREPGTPRHNFTNEVGHRKERETRTYSRRVYVSEDSDSSSSSKVNFSIGCESQGSKDPSEAIPHIVLQSELSLEARRVLAAKALANINEFLEEDEVKQKVEMWQKELNSRDGAWDKISTERDPFILCSLMWSWIEQLKEPIISKDDIDMLAKNSIESQDALNLLRKTSFDSEDGPHVYNTLKKVFKQTLEEKRKKLKEGTENPS", "length": 701, "header": "tr|A0A3Q3A4X3-1|A0A3Q3A4X3_CHICK Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PTPDC1 PE=3 SV=1 CANONICAL=A0A8V1AH94-1" }, "locus": { "chromosome": "12", "start_pos": 6296413, "end_pos": 6287574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067077.1", "url": "https://www.ensembl.org/id/ENSGALT00010067077.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041004.1", "url": "https://www.ensembl.org/id/ENSGALP00010041004.1" } ] } }, { "isoform_ac": "A0A8V1ACN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94/entry#A0A8V1ACN4-1", "sequence": { "sequence": "MQGSPRRRSARRRSSVVEVLSSSTHRVMVAISSLSPEELDATFPEKKRSSRRPTAKYTKVGERLRHVIPGHMQCSMACGGRACKYENPARWSDQEQAIKGLYSSWITDNILAMARPSTELIEKYNIIEQFEKCGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMAFALQEGRVAVHCHAGLGRTGVLVACYLVFATRMTADQAILFVRAKRPNSIQTRGQLLCIREFTQFLIPLRNVFACCEPKAHRVTLSQYLTRQRHLLHGYESRHLKHVPKLIHIVCKLLLDLAENRQVVEAELLDIADLSAEIEKTVSQLVSTQLDGDLARQDSDMSDSSHTHSATCDTQDSLFSLAHECDPLWKRRNVECLQPLSHVRRRLSYSDSDLRRTEFLLEQGETAWTVPAQILLCNKLKQNSSEESSATDEQKPQLDLNKEALVRNTCTIWSQTKFNLDGQKDGSSLYQRRNSTKEVQRSRTFSSGLASLHYTREPGTPRHNFTNEVGHRKERETRTYSRRVYVSEDSDSSSSSKVNFSIGCESQGSKDPSEAIPHIVLQSELSLEARRVLAAKALANINEFLEEDEVKQKVEMWQKELNSRDGAWDKISTERDPFILCSLMWSWIEQLKEPIISKDDIDMLAKNSIESQDALNLLRKEQCQTILCILHCVVNLQTLPADVEEALLVRAIKAFTKTSFDSEDGPHVYNTLKKVFKQTLEEKRKKLKEGTENPS", "length": 757, "header": "tr|A0A8V1ACN4-1|A0A8V1ACN4_CHICK Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PTPDC1 PE=3 SV=1 CANONICAL=A0A8V1AH94-1" }, "locus": { "chromosome": "12", "start_pos": 6294373, "end_pos": 6287574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067068.1", "url": "https://www.ensembl.org/id/ENSGALT00010067068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040998.1", "url": "https://www.ensembl.org/id/ENSGALP00010040998.1" } ] } }, { "isoform_ac": "A0A8V1AFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94/entry#A0A8V1AFA4-1", "sequence": { "sequence": "MAAGVLLQNELPYSSLLESSVYLANMSSGSSRRPTAKYTKVGERLRHVIPGHMQCSMACGGRACKYENPARWSDQEQAIKGLYSSWITDNILAMARPSTELIEKYNIIEQFEKCGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMAFALQEGRVAVHCHAGLGRTGVLVACYLVFATRMTADQAILFVRAKRPNSIQTRGQLLCIREFTQFLIPLRNVFACCEPKAHRVTLSQYLTRQRHLLHGYESRHLKHVPKLIHIVCKLLLDLAENRQVVEAELLDIADLSAEIEKTVSQLVSTQLDGDLARQDSDMSDSSHTHSATCDTQDSLFSLAHECDPLWKRRNVECLQPLSHVRRRLSYSDSDLRRTEFLLEQGETAWTVPAQILLCNKLKQNSSEESSATDEQKPQLDLNKEALVRNTCTIWSQTKFNLDGQKDGSSLYQRRNSTKEVQRSRTFSSGLASLHYTREPGTPRHNFTNEVGHRKERETRTYSRRVYVSEDSDSSSSSKVNFSIGCESQGSKDPSEAIPHIVLQSELSLEARRVLAAKALANINEFLEEDEVKQKVEMWQKELNSRDGAWDKISTERDPFILCSLMWSWIEQLKEPIISKDDIDMLAKNSIESQDALNLLRKVDVLYVNALLEHILLNYSFVTFKHGI", "length": 689, "header": "tr|A0A8V1AFA4-1|A0A8V1AFA4_CHICK Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PTPDC1 PE=3 SV=1 CANONICAL=A0A8V1AH94-1" }, "locus": { "chromosome": "12", "start_pos": 6296413, "end_pos": 6288782, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067074.1", "url": "https://www.ensembl.org/id/ENSGALT00010067074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041002.1", "url": "https://www.ensembl.org/id/ENSGALP00010041002.1" } ] } }, { "isoform_ac": "A0A8V1AH94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94/entry#A0A8V1AH94-1", "sequence": { "sequence": "MQGSPRRRSAVSIFSNFFQGRRHSSSDPLLRIIQRRRSSVVEVLSSSTHRVMVAISSLSPEELDATFPEKKRSSRRPTAKYTKVGERLRHVIPGHMQCSMACGGRACKYENPARWSDQEQAIKGLYSSWITDNILAMARPSTELIEKYNIIEQFEKCGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMAFALQEGRVAVHCHAGLGRTGVLVACYLVFATRMTADQAILFVRAKRPNSIQTRGQLLCIREFTQFLIPLRNVFACCEPKAHRVTLSQYLTRQRHLLHGYESRHLKHVPKLIHIVCKLLLDLAENRQVVEAELLDIADLSAEIEKTVSQLVSTQLDGDLARQDSDMSDSSHTHSATCDTQDSLFSLAHECDPLWKRRNVECLQPLSHVRRRLSYSDSDLRRTEFLLEQGETAWTVPAQILLCNKLKQNSSEESSATDEQKPQLDLNKEALVRNTCTIWSQTKFNLDGQKDGSSLYQRRNSTKEVQRSRTFSSGLASLHYTREPGTPRHNFTNEVGHRKERETRTYSRRVYVSEDSDSSSSSKVNFSIGCESQGSKDPSEAIPHIVLQSELSLEARRVLAAKALANINEFLEEDEVKQKVEMWQKELNSRDGAWDKISTERDPFILCSLMWSWIEQLKEPIISKDDIDMLAKNSIESQDALNLLRKEQCQTILCILHCVVNLQTLPADVEEALLVRAIKAFTKTSFDSEDGPHVYNTLKKVFKQTLEEKRKKLKEGTENPS", "length": 781, "header": "tr|A0A8V1AH94-1|A0A8V1AH94_CHICK Isoform 1 of Protein tyrosine phosphatase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PTPDC1 PE=3 SV=1 CANONICAL=A0A8V1AH94-1" }, "locus": { "chromosome": "12", "start_pos": 6294373, "end_pos": 6287574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067070.1", "url": "https://www.ensembl.org/id/ENSGALT00010067070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041000.1", "url": "https://www.ensembl.org/id/ENSGALP00010041000.1" } ] } }, { "isoform_ac": "E1C6I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94/entry#E1C6I5-1", "sequence": { "sequence": "MAAGVLLQNELPYSSLLESSVYLANMSSGSSRRPTAKYTKVGERLRHVIPGHMQCSMACGGRACKYENPARWSDQEQAIKGLYSSWITDNILAMARPSTELIEKYNIIEQFEKCGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMAFALQEGRVAVHCHAGLGRTGVLVACYLVFATRMTADQAILFVRAKRPNSIQTRGQLLCIREFTQFLIPLRNVFACCEPKAHRVTLSQYLTRQRHLLHGYESRHLKHVPKLIHIVCKLLLDLAENRQVVEAELLDIADLSAEIEKTVSQLVSTQLDGDLARQDSDMSDSSHTHSATCDTQDSLFSLAHECDPLWKRRNVECLQPLSHVRRRLSYSDSDLRRTEFLLEQGETAWTVPAQILLCNKLKQNSSEESSATDEQKPQLDLNKEALVRNTCTIWSQTKFNLDGQKDGSSLYQRRNSTKEVQRSRTFSSGLASLHYTREPGTPRHNFTNEVGHRKERETRTYSRRVYVSEDSDSSSSSKVNFSIGCESQGSKDPSEAIPHIVLQSELSLEARRVLAAKALANINEFLEEDEVKQKVEMWQKELNSRDGAWDKISTERDPFILCSLMWSWIEQLKEPIISKDDIDMLAKNSIESQDALNLLRKEQCQTILCILHCVVNLQTLPADVEEALLVRAIKAFTKTSFDSEDGPHVYNTLKKVFKQTLEEKRKKLKEGTENPS", "length": 738, "header": "tr|E1C6I5-1|E1C6I5_CHICK Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PTPDC1 PE=3 SV=2 CANONICAL=A0A8V1AH94-1" }, "locus": { "chromosome": "12", "start_pos": 6296413, "end_pos": 6287574, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067081.1", "url": "https://www.ensembl.org/id/ENSGALT00010067081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041006.1", "url": "https://www.ensembl.org/id/ENSGALP00010041006.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 212, "end_pos": 279, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AH94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH94" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 297, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHA2-1", "uniprot_ac": "A0A8V1AHA2", "uniprot_id": "A0A8V1AHA2_CHICK", "mass": { "chemical_mass": 14691.0, "monoisotopic_mass": 14691.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "IF rod domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AHA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2", "locus": {} } ], "crossref": [ { "id": "A0A8V1AHA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45721:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45721:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AHA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTPSQRRSGRGGGPSGTPLSPTRITRLQEKEDLQELNDRLAVYIDKVRSLELENAGLRLRITESEEVVSREVSGIKAAYEAELADARKTLDSVAKERARLQLELSKVREEHKELKARWGRRWVPGGRDP", "length": 130, "header": "tr|A0A8V1AHA2-1|A0A8V1AHA2_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AHA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2/entry#A0A8V1AHA2-1", "sequence": { "sequence": "MSTPSQRRSGRGGGPSGTPLSPTRITRLQEKEDLQELNDRLAVYIDKVRSLELENAGLRLRITESEEVVSREVSGIKAAYEAELADARKTLDSVAKERARLQLELSKVREEHKELKARWGRRWVPGGRDP", "length": 130, "header": "tr|A0A8V1AHA2-1|A0A8V1AHA2_CHICK Isoform 1 of IF rod domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AHA2-1" }, "locus": { "chromosome": "25", "start_pos": 338505, "end_pos": 337078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068006.1", "url": "https://www.ensembl.org/id/ENSGALT00010068006.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041749.1", "url": "https://www.ensembl.org/id/ENSGALP00010041749.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA2" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 130, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHB4-1", "uniprot_ac": "A0A8V1AHB4", "uniprot_id": "A0A8V1AHB4_CHICK", "mass": { "chemical_mass": 73109.0, "monoisotopic_mass": 73109.0 }, "refseq": { "ac": "XP_015151487", "name": "SH2B adapter protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151487" }, "gene_names": [ { "name": "SH2B1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ] }, { "name": "SH2B1", "type": "synonym", "evidence": [ { "id": "XP_015151487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151487" } ] } ], "protein_names": [ { "name": "SH2B adapter protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AHB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4/entry#names_and_taxonomy" } ] }, { "name": "Adapter protein with pleckstrin homology and Src homology 2 domains", "type": "synonym", "evidence": [ { "id": "A0A8V1AHB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4/entry#names_and_taxonomy" } ] }, { "name": "SH2 and PH domain-containing adapter protein APS", "type": "synonym", "evidence": [ { "id": "A0A8V1AHB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4/entry#names_and_taxonomy" } ] }, { "name": "SH2B adapter protein 2", "type": "synonym", "evidence": [ { "id": "XP_015151487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151487" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151487" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH2B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AHB4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01231", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01231", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10411", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10411", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771172", "url": "https://www.ncbi.nlm.nih.gov/gene/771172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771172", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771172", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQKWEKS", "url": "https://omabrowser.org/oma/group/TQKWEKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHB4", "url": "https://www.orthodb.org/?gene=A0A8V1AHB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10872:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10872:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1433559", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433559", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151487", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGDALCQEPSSPLPDWREFCELHAQAAAVDFAQKFCQFLKENPHYDTPGAEASFSHHFAANFLDIFSVEVSRVFVSDSPTKYNIVPFVGLQNCHVPYGREVAQRKEETSTESLDSMEAPLGAGRYLSPAQQAQARKVSSYGQSRSSEDVSVHASAKPKFKKGFSLRNMSLCVVDGMKEMWHRRSSPEPGAEAAPGNRRAEREPWGKEPADPREKWTHKLRLSKAQSSKVELVDIQREGTLRYMVADDTNCVGSSQWQKCRLLLRKAVKVEGERFLLEFYVPPKASKPKVSIPLSAIIEVRTTMPLEMPDKDNTFVLKVENGAEYILETIDSLQKHSWVADIQDCIDPGDSGDDIELASCAQGACLPGRASSCSCEFLADDAHRLPDRCALPSAHNATTTAVPTPHGRGRDSMGELLAHVPLESFLQTLESAPTASAHLAGEDSEADTEINLSDFPWFHGTLSRIKAAQLVLFGGARSHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNESGQCHVQHLWFQSIFDMLRHFHTHPIPLESGGAADITLRSYVVAQSLQPDVGPPPALVPQPPLCRTDPPPPHYFCNTAPAAPPVPPPAEGVAVPPAVPAPYHRLEGALGPRSRSDSAERRPEPPATGTEDYHDADGARSRTRAVENQYSFY", "length": 664, "header": "tr|A0A8V1AHB4-1|A0A8V1AHB4_CHICK Isoform 1 of SH2B adapter protein 2 OS=Gallus gallus OX=9031 GN=SH2B1 PE=3 SV=1 CANONICAL=A0A8V1AHB4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4/entry#A0A8V1AHB4-1", "sequence": { "sequence": "MNGDALCQEPSSPLPDWREFCELHAQAAAVDFAQKFCQFLKENPHYDTPGAEASFSHHFAANFLDIFSVEVSRVFVSDSPTKYNIVPFVGLQNCHVPYGREVAQRKEETSTESLDSMEAPLGAGRYLSPAQQAQARKVSSYGQSRSSEDVSVHASAKPKFKKGFSLRNMSLCVVDGMKEMWHRRSSPEPGAEAAPGNRRAEREPWGKEPADPREKWTHKLRLSKAQSSKVELVDIQREGTLRYMVADDTNCVGSSQWQKCRLLLRKAVKVEGERFLLEFYVPPKASKPKVSIPLSAIIEVRTTMPLEMPDKDNTFVLKVENGAEYILETIDSLQKHSWVADIQDCIDPGDSGDDIELASCAQGACLPGRASSCSCEFLADDAHRLPDRCALPSAHNATTTAVPTPHGRGRDSMGELLAHVPLESFLQTLESAPTASAHLAGEDSEADTEINLSDFPWFHGTLSRIKAAQLVLFGGARSHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNESGQCHVQHLWFQSIFDMLRHFHTHPIPLESGGAADITLRSYVVAQSLQPDVGPPPALVPQPPLCRTDPPPPHYFCNTAPAAPPVPPPAEGVAVPPAVPAPYHRLEGALGPRSRSDSAERRPEPPATGTEDYHDADGARSRTRAVENQYSFY", "length": 664, "header": "tr|A0A8V1AHB4-1|A0A8V1AHB4_CHICK Isoform 1 of SH2B adapter protein 2 OS=Gallus gallus OX=9031 GN=SH2B1 PE=3 SV=1 CANONICAL=A0A8V1AHB4-1" }, "locus": { "chromosome": "19", "start_pos": 4609402, "end_pos": 4600970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070851.1", "url": "https://www.ensembl.org/id/ENSGALT00010070851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043542.1", "url": "https://www.ensembl.org/id/ENSGALP00010043542.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771172", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771172", "resource": "KEGG Pathway" }, { "id": "R-GGA-1433559", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1433559", "resource": "Reactome", "description": "Regulation of KIT signaling" }, { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LHY5-1", "protein_name": "Lnk, isoform D", "gene_name": "Lnk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGNSTGANTSAFSAGGYIGPTSASSHHSLGTSSAAAAAAAGSDLIPAPIGTGNAMGVSSYAYGGTSWEEFCERHARVAASDFAKACITYINGNLPPEEARNIQHRSFAQKFVESFSAHYDTEFFKRRSTLKSGAGSLDFEEEHEVPKLLSKSLLRRLSFKGLRKGKISLLQAFFHKNSDDLDGSGGSGKQSKTKLAKIVVECRKEGTVNNLTPESLDQPTGSQKWEKCRLVLVKAVGGYMLEFYTPHKATKPRSGVFCFLISEARETTALEMPDRLNTFVLKADNNMEYVIEAESAEEMRSWLATIRYCMRTPPTQQPTIESDGVMASAMQTSPTLPSPNPIGGIQNPQYQQQRGSNGNLVGGGAPLTSSLSADSALGQGGATSASELNVINELGTSPTSGPPDIPVRPHRGEQRLSASSNFDGIEGTENDADVADLTAEMSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTISEKGQCRVQHLWFPSIQEMLEHFRHNPIPLESGGTSDVTLTEWVHSHSRLNDPTTAANHDSGQLNDLSTNGNGNGNGNGYDNGQGSSTASNAAGGTASGAAGGGHPSPRHCNEVITMNLSVRLKTNEIELPQEPTHVYFPEQVYFHLDPTTLTVHGSPPPAQNFLDQPHLRASNASLQAAAHHQAGSSGNRHPSDGGSNSGGAGGGSGSSGGAECTGRAVDNQYSFT", "length": 728 }, "evidence": [ { "id": "A0A8V1AHB4", "url": "https://omabrowser.org/oma/group/A0A8V1AHB4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A286Y8A3-1", "protein_name": "SH2B adapter protein 2", "gene_name": "sh2b2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGAGAPSSPEHSSCTLPDWKEFCELHARASAADFAYKFRRFITENPCYDSPGADVSFSQHFAQHFLTCFSAALDQLQDPGSPGHTSAPKYSIVPFVGIQSCTLPFSHDLYHRRKDVGASSESLDSMDSGAGGQEQQTPTRKMATVSQSRSSEDVSLGRRKTRFKKGFSLRNMSLSVVDGVKEIWHRRASPEPDPSGSSRRTNGAESMGSEHWSQKLRLPRGTQGHKTELLEIQREGALRYMVADDTNCMGAAQWQKCRLLLRKTTAYVEPGEKFQLEFYVPPKSSKPKVSVPLSAIVEVRTTMPLEMPDKDNTFVLKVENGAEYILETIDSLQKNSWVADIQDCIDPGDSGDDIELASCAHSQPPKDFSLVSSCSCELLCDGSHRGSAAGDQSSAARCQEPPVTQHPSHVPLERFLQSPEAQNTNTASGSPGETPREGEGDASLSGYPWFHGTLSRVRAAQLVLAGGARSHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSVNDSGQCHVHHLWFQTVADMLRHFHTHPIPLESGGSTDITLRSYVQVQRSPTDAVAPHVPVAPRDPSACRSESTHPPSGAAETPLSSSSSSSPMAQPSTGLHSRSNSAERLLEPAAAATADDYHDTDGTRRTRAVENQYSFY", "length": 645 }, "evidence": [ { "id": "A0A8V1AHB4", "url": "https://omabrowser.org/oma/group/A0A8V1AHB4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O14492-1", "protein_name": "SH2B adapter protein 2", "gene_name": "SH2B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGAGPGPAAAAPVPVPVPVPDWRQFCELHAQAAAVDFAHKFCRFLRDNPAYDTPDAGASFSRHFAANFLDVFGEEVRRVLVAGPTTRGAAVSAEAMEPELADTSALKAAPYGHSRSSEDVSTHAATKARVRKGFSLRNMSLCVVDGVRDMWHRRASPEPDAAAAPRTAEPRDKWTRRLRLSRTLAAKVELVDIQREGALRFMVADDAAAGSGGSAQWQKCRLLLRRAVAEERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTELSCTRGGCLASRVASCSCELLTDAVDLPRPPETTAVGAVVTAPHSRGRDAVRESLIHVPLETFLQTLESPGGSGSDSNNTGEQGAETDPEAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTHPIPLESGGSADITLRSYVRAQDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACPPASPSDAAGASSSSASSSSAASGPAPPRPVEGQLSARSRSNSAERLLEAVAATAAEEPPEAAPGRARAVENQYSFY", "length": 632 }, "evidence": [ { "id": "A0A8V1AHB4", "url": "https://omabrowser.org/oma/group/A0A8V1AHB4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JID9-1", "protein_name": "SH2B adapter protein 2", "gene_name": "Sh2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGATPSSAAAPAPVPDWRQFCELHAQVAAVDFAHKFCRFLRDNPTYDTPDAGTSFSRHFAANFLAVFSEEVRRVLGSAADTMEPEPAVTSVTSALKTATYGHSRSSEDVSAHAATKARVRKGFSLRNMSLCVVDGVRDLWHRRSSPEPDGGATPKAAEPASEPRDKWTRRLRLARTLAAKVELVDIQREGALRFMVADDAASGPGGTAQWQKCRLLLRRAVAGERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTGLSCARGGCLASRVASCSCELLTDADMPRPPETTTAVGAVVTAPHGRARDTVGESLAHVPLETFLQTLESSGGVSENNNPGDEGAELDTDAEAELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVFDMLRHFHTHPIPLESGGSADITLRSYVRAQGPPPDPGPAPNTAAPVPACWTEPAGQHYFSSLATATCPPASPSNGAGASSSSGSSSSATSLPPRPAEGPLSAHSRSNSTEHLLDAASGATEEPTEATLGRARAVENQYSFY", "length": 621 }, "evidence": [ { "id": "A0A8V1AHB4", "url": "https://omabrowser.org/oma/group/A0A8V1AHB4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z200-1", "protein_name": "SH2B adapter protein 2", "gene_name": "Sh2b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGATPGSAAAPAPVPDWRQFCELHAQVAAVDFAHKFCRFLRDNPTYDTPDAGTSFSRHFAANFLAVFSEEVRRVLGTAADTMEPEPAVTSVTSALKTATYGHSRSSEDVSAHVATKARVRKGFSLRNMSLCVVDGVRDLWHRRASPEPEGGATPKTTEPVSEPRDKWTRRLRLARTLAAKVELVDIQREGALRFMVADDAASGPGGTAQWQKCRLLLRRAVAGERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTGLSCARGGCLASRVTSCSCELLTEADMPRPPETMTAVGAVVTAPHGRARDTVGESLAHVPLETFLQTLESSGGVSESNNTGDEGAELDPDAEAELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVFDMLRHFHTHPIPLESGGSADITLRSYVRAQGPPPDPGPAPNTAAPVPACWTEPAGQHYFSSLATATCPPTSPSNGAGASSSSGSSSSATSVPPRPAEGPLSARSRSNSTEHLLEAASGATEEPADATLGRARAVENQYSFY", "length": 621 }, "evidence": [ { "id": "A0A8V1AHB4", "url": "https://omabrowser.org/oma/group/A0A8V1AHB4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" }, { "name": "transmembrane receptor protein tyrosine kinase adaptor activity", "id": "GO:0005068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005068", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 347, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AHB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB4" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 457, "end_pos": 555, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHB5-1", "uniprot_ac": "A0A8V1AHB5", "uniprot_id": "A0A8V1AHB5_CHICK", "mass": { "chemical_mass": 123241.0, "monoisotopic_mass": 123241.0 }, "refseq": {}, "gene_names": [ { "name": "PHF2", "type": "recommended", "evidence": [ { "id": "A0A8V1AHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ] } ], "protein_names": [ { "name": "Lysine-specific demethylase PHF2", "type": "recommended", "evidence": [ { "id": "A0A8V1AHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5/entry#names_and_taxonomy" } ] }, { "name": "Lysine-specific demethylase phf2", "type": "synonym", "evidence": [ { "id": "A0A8V1AHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5/entry#names_and_taxonomy" } ] }, { "name": "PHD finger protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AHB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5", "locus": { "chromosome": "12", "start_pos": 6479220, "end_pos": 6561351, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027692", "url": "https://www.ensembl.org/id/ENSGALG00010027692" } ] } } ], "crossref": [ { "id": "A0A8V1AHB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15554", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15554", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACQ9", "url": "https://www.orthodb.org/?gene=A0A8V1ACQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFD0", "url": "https://www.orthodb.org/?gene=A0A8V1AFD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHB5", "url": "https://www.orthodb.org/?gene=A0A8V1AHB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23123", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23123", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17811", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17811", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ACQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQADEQPPKLPSGRSRRQPRSPLRESGVVLKGANMATVPVYCICRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNCEKTHGKSTLKKKRNWHKHDTGQSTEVKPVQNGSQIFIKELRSRTFPSAEDIVVKVPGSQLTTEYLEENGFTEPILVPKKDGLGLSVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIKPASANISLYERWQSAANHSEMFFADQVDKCYKCTVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKIVSLTQFPNYETACWYMGKHLLETFKGLHKAGQQPPAHLLQGAKILNGAFRSWTKKQALAEHEDELPENFKPAQLIKDLAKEIRLSENASKASKADTSANTNAEEICPVEKEEAPSPIQVTPPSPPVEKLPKKKTPKTVKTPKQLKPSKPPKPPKPPKPPKPPKTPKVKGEGKKKGKKAKESPPPAIPNLDLLEAHTKEALTKIETPKKGKATKNVLSVPNKETPTKQNEVEKFEVREQNKSKTEAKWKYKNSKPDSLLKMEEEHKSEKTPLSGNKDNKFTFSFANKKLLGSKGVKTQLNTSVFGSLQNFKEDKAKPVRDEYEYVSDDGELKIDEFPIRRKKNTTKRELPFFSDKKDTMQHTPVKKPKVESVSYKSDDSSDEDLLHIDTEAKPGRNSKVKKESGSSAGILDLLQASKEVGGLEYNTNSQPPASPSTQEAIQGMLSMANLQSSDSCLQASWGTNQAKNNSISSQNSKKTGGGGSKNAGKRLLKKSTKNSIDIEDYDEDQDHLDACFKDSDYVYPSLESDEDNPVFKSRSKKRKSSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKGKKKKNTKKKLSTNNVNKPAQEGSSPEPKLESHASSLTDHEYTAGASTFGAAQPNRGSQPMAPGVFLTQRRPSSSSQNNASAKGADDTCGSLQNWSEMKILAWNCVFVVKWRHESPRGPW", "length": 1104, "header": "tr|A0A8V1AHB5-1|A0A8V1AHB5_CHICK Isoform 1 of Lysine-specific demethylase PHF2 OS=Gallus gallus OX=9031 GN=PHF2 PE=1 SV=1 CANONICAL=A0A8V1AHB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5/entry#A0A8V1ACQ9-1", "sequence": { "sequence": "MERIMAAEPHCSCVGVEEEEAPDIDIYHCPNCEKTHGKSTLKKKRNWHKHDTGQSTEVKPVQNGSQIFIKELRSRTFPSAEDIVVKVPGSQLTTEYLEENGFTEPILVPKKDGLGLSVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCKMKLKEFVDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIKPASANISLYERWQSAANHSEMFFADQVDKCYKCTVKQGQTLFIPSGWIYATLTPVDCLAFAGHFLHSLSVEMQMRAYEVERRLKIVSLTQFPNYETACWYMGKHLLETFKGLHKAGQQPPAHLLQGAKILNGAFRSWTKKQALAEHEDELPENFKPAQLIKDLAKEIRLSENASKASKADTSANTNAEEICPVEKEEAPSPIQVTPPSPPVEKLPKKKTPKTVKTPKQLKPSKPPKPPKPPKPPKPPKTPKVKGEGKKKGKKAKESPPPAIPNLDLLEAHTKEALTKIETPKKGKATKNVLSVPNKETPTKQNEVEKFEVREQNKSKTEAKWKYKNSKPDSLLKMEEEHKSEKTPLSGNKDNKFTFSFANKKLLGSKGVKTQLNTSVFGSLQNFKEDKAKPVRDEYEYVSDDGELKIDEFPIRRKKNTTKRELPFFSDKKDTMQHTPVKKPKVESVSYKSDDSSDEDLLHIDTEAKPGRNSKVKKESGSSAGILDLLQASKEVGGLEYNTNSQPPASPSTQEAIQGMLSMANLQSSDSCLQASWGTNQAKNNSISSQNSKKTGGGGSKNAGKRLLKKSTKNSIDIEDYDEDQDHLDACFKDSDYVYPSLESDEDNPVFKSRSKKRKSSDDAPYSPTARVGPSVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKGKKKKNTKKKLSTNNVNKPAQEGSSPEPKLESHASSLTDHEYTAGASTFGAAQPNRGSQPMAPGVFLTQRRPSSSSQNNASAKGKRTKKGMATAKQRLGKILKIHRNGKLLL", "length": 1040, "header": "tr|A0A8V1ACQ9-1|A0A8V1ACQ9_CHICK Computationally mapped isoform of PHD finger protein 2 OS=Gallus gallus OX=9031 GN=PHF2 PE=1 SV=1 CANONICAL=A0A8V1AHB5-1" }, "locus": { "chromosome": "12", "start_pos": 6541843, "end_pos": 6480053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067118.1", "url": "https://www.ensembl.org/id/ENSGALT00010067118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041023.1", "url": "https://www.ensembl.org/id/ENSGALP00010041023.1" } ] } }, { "isoform_ac": "A0A8V1AFD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5/entry#A0A8V1AFD0-1", "sequence": { "sequence": 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"length": 1096, "header": "tr|A0A8V1AFD0-1|A0A8V1AFD0_CHICK Computationally mapped isoform of Lysine-specific demethylase PHF2 OS=Gallus gallus OX=9031 GN=PHF2 PE=1 SV=1 CANONICAL=A0A8V1AHB5-1" }, "locus": { "chromosome": "12", "start_pos": 6561244, "end_pos": 6480053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067123.1", "url": "https://www.ensembl.org/id/ENSGALT00010067123.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041027.1", "url": "https://www.ensembl.org/id/ENSGALP00010041027.1" } ] } }, { "isoform_ac": "A0A8V1AHB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5/entry#A0A8V1AHB5-1", "sequence": { "sequence": 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"length": 1104, "header": "tr|A0A8V1AHB5-1|A0A8V1AHB5_CHICK Isoform 1 of Lysine-specific demethylase PHF2 OS=Gallus gallus OX=9031 GN=PHF2 PE=1 SV=1 CANONICAL=A0A8V1AHB5-1" }, "locus": { "chromosome": "12", "start_pos": 6561244, "end_pos": 6481380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067121.1", "url": "https://www.ensembl.org/id/ENSGALT00010067121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041025.1", "url": "https://www.ensembl.org/id/ENSGALP00010041025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "histone H4K20 demethylase activity", "id": "GO:0035575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "histone demethylase activity", "id": "GO:0032452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032452", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "histone H3K9 demethylase activity", "id": "GO:0032454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "histone H3K4me3 reader activity", "id": "GO:0140002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHD0-1", "uniprot_ac": "A0A8V1AHD0", "uniprot_id": "A0A8V1AHD0_CHICK", "mass": { "chemical_mass": 37168.0, "monoisotopic_mass": 37168.0 }, "refseq": {}, "gene_names": [ { "name": "ORAI3", "type": "recommended", "evidence": [ { "id": "A0A8V1AHD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ] } ], "protein_names": [ { "name": "ORAI calcium release-activated calcium modulator 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AHD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ORAI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0", "locus": { "chromosome": "19", "start_pos": 4635480, "end_pos": 4623598, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029304", "url": "https://www.ensembl.org/id/ENSGALG00010029304" } ] } } ], "crossref": [ { "id": "A0A8V1AHD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC33", "url": "https://www.orthodb.org/?gene=A0A8V1AC33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHD0", "url": "https://www.orthodb.org/?gene=A0A8V1AHD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJE7", "url": "https://www.orthodb.org/?gene=A0A8V1AJE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJF2", "url": "https://www.orthodb.org/?gene=A0A8V1AJF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALH4", "url": "https://www.orthodb.org/?gene=A0A8V1ALH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN25", "url": "https://www.orthodb.org/?gene=A0A8V1AN25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31501:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31501:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AC33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN25", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLGAGPGVALTNAAAITCRGAGLPAAPPFPAGHVAGARRCLGSGGGGGGSGTRRLPGRRARAGQRAAAPPEPPAAPPCPQAVSASLMMSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 345, "header": "tr|A0A8V1AHD0-1|A0A8V1AHD0_CHICK Isoform 1 of ORAI calcium release-activated calcium modulator 3 OS=Gallus gallus OX=9031 GN=ORAI3 PE=3 SV=1 CANONICAL=A0A8V1AHD0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0/entry#A0A8V1AC33-1", "sequence": { "sequence": "MMSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQAASSVPLSDKKVAPAMTHWLS", "length": 277, "header": "tr|A0A8V1AC33-1|A0A8V1AC33_CHICK Computationally mapped isoform of ORAI calcium release-activated calcium modulator 3 OS=Gallus gallus OX=9031 GN=ORAI3 PE=3 SV=1 CANONICAL=A0A8V1AHD0-1" }, "locus": { "chromosome": "19", "start_pos": 4635309, "end_pos": 4626240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070870.1", "url": "https://www.ensembl.org/id/ENSGALT00010070870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043561.1", "url": "https://www.ensembl.org/id/ENSGALP00010043561.1" } ] } }, { "isoform_ac": "A0A8V1AHD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0/entry#A0A8V1AHD0-1", "sequence": { "sequence": "MGLGAGPGVALTNAAAITCRGAGLPAAPPFPAGHVAGARRCLGSGGGGGGSGTRRLPGRRARAGQRAAAPPEPPAAPPCPQAVSASLMMSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 345, "header": "tr|A0A8V1AHD0-1|A0A8V1AHD0_CHICK Isoform 1 of ORAI calcium release-activated calcium modulator 3 OS=Gallus gallus OX=9031 GN=ORAI3 PE=3 SV=1 CANONICAL=A0A8V1AHD0-1" }, "locus": { "chromosome": "19", "start_pos": 4631468, "end_pos": 4624149, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070867.1", "url": "https://www.ensembl.org/id/ENSGALT00010070867.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043558.1", "url": "https://www.ensembl.org/id/ENSGALP00010043558.1" } ] } }, { "isoform_ac": "A0A8V1AJE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0/entry#A0A8V1AJE7-1", "sequence": { "sequence": "MHSLTPCSVQLWGCFGQELASLMMSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 280, "header": "tr|A0A8V1AJE7-1|A0A8V1AJE7_CHICK Computationally mapped isoform of ORAI calcium release-activated calcium modulator 3 OS=Gallus gallus OX=9031 GN=ORAI3 PE=3 SV=1 CANONICAL=A0A8V1AHD0-1" }, "locus": { "chromosome": "19", "start_pos": 4631468, "end_pos": 4625705, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070864.1", "url": "https://www.ensembl.org/id/ENSGALT00010070864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043555.1", "url": "https://www.ensembl.org/id/ENSGALP00010043555.1" } ] } }, { "isoform_ac": "A0A8V1AJF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0/entry#A0A8V1AJF2-1", "sequence": { "sequence": "MQGDSSSSVALIYKGRLLQSSAPPQVRLLLYSNRNKRWRAGSASSTTHRPGPAPGFPQRASLMMSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 320, "header": "tr|A0A8V1AJF2-1|A0A8V1AJF2_CHICK Computationally mapped isoform of ORAI calcium release-activated calcium modulator 3 OS=Gallus gallus OX=9031 GN=ORAI3 PE=3 SV=1 CANONICAL=A0A8V1AHD0-1" }, "locus": { "chromosome": "19", "start_pos": 4631468, "end_pos": 4623948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070869.1", "url": "https://www.ensembl.org/id/ENSGALT00010070869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043560.1", "url": "https://www.ensembl.org/id/ENSGALP00010043560.1" } ] } }, { "isoform_ac": "A0A8V1ALH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0/entry#A0A8V1ALH4-1", "sequence": { "sequence": "MLALTCKVGCRATSLTVLQQFQVSLCNPTWFSCASLMMSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 294, "header": "tr|A0A8V1ALH4-1|A0A8V1ALH4_CHICK Computationally mapped isoform of ORAI calcium release-activated calcium modulator 3 OS=Gallus gallus OX=9031 GN=ORAI3 PE=3 SV=1 CANONICAL=A0A8V1AHD0-1" }, "locus": { "chromosome": "19", "start_pos": 4631468, "end_pos": 4625998, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070863.1", "url": "https://www.ensembl.org/id/ENSGALT00010070863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043554.1", "url": "https://www.ensembl.org/id/ENSGALP00010043554.1" } ] } }, { "isoform_ac": "A0A8V1AN25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0/entry#A0A8V1AN25-1", "sequence": { "sequence": "MRRRSRAEGRGCRQPPHFLRVTWRGPGVALAAVEAAEAPVPGGSRGAAPEPASGQQRASLMMSSELNVPVDPSTPACCSEPGTKGMDYRDWVRRSYLELVTSNHHSVQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLEMQYKYPQMLLIAFSACTTVLVAVHLFALLISTCILPNVEAVSNIHNLNSISESPHERMHPYIELAWGFSTVLGILLFLAEVVLLCWIKFLPVDSILKNDTTTIQKPSGHAGWQAALVSTIIMVPVGLIFVVFTIHFYRSLVRHKTERHNREIEELHKLKVQLDGHDRGMQVV", "length": 318, "header": "tr|A0A8V1AN25-1|A0A8V1AN25_CHICK Computationally mapped isoform of ORAI calcium release-activated calcium modulator 3 OS=Gallus gallus OX=9031 GN=ORAI3 PE=3 SV=1 CANONICAL=A0A8V1AHD0-1" }, "locus": { "chromosome": "19", "start_pos": 4631468, "end_pos": 4624186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070866.1", "url": "https://www.ensembl.org/id/ENSGALT00010070866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043557.1", "url": "https://www.ensembl.org/id/ENSGALP00010043557.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 101, "start_aa": "Thr", "end_pos": 101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr101", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "store-operated calcium entry", "id": "GO:0002115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "store-operated calcium channel activity", "id": "GO:0015279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 101 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHD9-1", "uniprot_ac": "A0A8V1AHD9", "uniprot_id": "A0A8V1AHD9_CHICK", "mass": { "chemical_mass": 63610.0, "monoisotopic_mass": 63610.0 }, "refseq": { "ac": "XP_420084", "name": "N-sulphoglucosamine sulphohydrolase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420084" }, "gene_names": [ { "name": "SGSH", "type": "recommended", "evidence": [ { "id": "A0A8V1AHD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9" } ] }, { "name": "SGSH", "type": "synonym", "evidence": [ { "id": "XP_420084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420084" } ] } ], "protein_names": [ { "name": "N-sulfoglucosamine sulfohydrolase", "type": "synonym", "evidence": [ { "id": "A0A8V1AHD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9/entry#names_and_taxonomy" } ] }, { "name": "N-sulphoglucosamine sulphohydrolase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_420084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420084" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420084.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420084" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGSH", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9", "locus": { "chromosome": "18", "start_pos": 10181043, "end_pos": 10177820, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029307", "url": "https://www.ensembl.org/id/ENSGALG00010029307" } ] } } ], "crossref": [ { "id": "A0A8V1AHD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16027", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16027", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422081", "url": "https://www.ncbi.nlm.nih.gov/gene/422081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MAYPMRM", "url": "https://omabrowser.org/oma/group/MAYPMRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHD9", "url": "https://www.orthodb.org/?gene=A0A8V1AHD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43108:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43108:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2024096", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_420084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420084", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHFGLTASPAAAPPAGRPAPPAAPDGFGTQTPGALHPAGGPARAGSEPFRPAHVTGAEEELRPPSTAGGGGGVGAMRVWALPLLLGALRLDGAPARNVLLLLADDGGFESGAYNNSAIRTPNLDALARRGLLFQNAFTSVSSCSPSRASVLTGLPQHQNGMYGLHQGVHHFNSFDAVRSLPGLLRQANIRTGIIGKKHVGPEAVYPFDFAYTEENSSVLQVGRNITRIKVLVRRFLQSQDVRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGWIPDWKPQLYRPEDVQVPHFVPDTPAARADLAAQYTTIGRMDQGIGLVLEELRRAGVLNSTLVIYTSDNGIPFPSGRTNLYWSGTAEPLLLSSPEHPGRWGQVSSAFASLLDLTPTILDWFSIPYPSYSIFGTKRVQLTGKSLLPALQSEQPWATAFSSQSHHEATMYYPMRAIQHRQFRLIHNLNYKMPFPIDQDFYVSPTFQDLLNRTRAGQPTHWNKTLHQYYYRDRWELFDCSQDPTESHNLASDPRYAAIFQMLRAQLLKWQWDTGDPWVCAPDAVLEEKLSPQCQPLHNEL", "length": 576, "header": "tr|A0A8V1AHD9-1|A0A8V1AHD9_CHICK Isoform 1 of N-sulfoglucosamine sulfohydrolase OS=Gallus gallus OX=9031 GN=SGSH PE=1 SV=1 CANONICAL=A0A8V1AHD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9/entry#A0A8V1AHD9-1", "sequence": { "sequence": "MAHFGLTASPAAAPPAGRPAPPAAPDGFGTQTPGALHPAGGPARAGSEPFRPAHVTGAEEELRPPSTAGGGGGVGAMRVWALPLLLGALRLDGAPARNVLLLLADDGGFESGAYNNSAIRTPNLDALARRGLLFQNAFTSVSSCSPSRASVLTGLPQHQNGMYGLHQGVHHFNSFDAVRSLPGLLRQANIRTGIIGKKHVGPEAVYPFDFAYTEENSSVLQVGRNITRIKVLVRRFLQSQDVRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGWIPDWKPQLYRPEDVQVPHFVPDTPAARADLAAQYTTIGRMDQGIGLVLEELRRAGVLNSTLVIYTSDNGIPFPSGRTNLYWSGTAEPLLLSSPEHPGRWGQVSSAFASLLDLTPTILDWFSIPYPSYSIFGTKRVQLTGKSLLPALQSEQPWATAFSSQSHHEATMYYPMRAIQHRQFRLIHNLNYKMPFPIDQDFYVSPTFQDLLNRTRAGQPTHWNKTLHQYYYRDRWELFDCSQDPTESHNLASDPRYAAIFQMLRAQLLKWQWDTGDPWVCAPDAVLEEKLSPQCQPLHNEL", "length": 576, "header": "tr|A0A8V1AHD9-1|A0A8V1AHD9_CHICK Isoform 1 of N-sulfoglucosamine sulfohydrolase OS=Gallus gallus OX=9031 GN=SGSH PE=1 SV=1 CANONICAL=A0A8V1AHD9-1" }, "locus": { "chromosome": "18", "start_pos": 10180825, "end_pos": 10178015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070877.1", "url": "https://www.ensembl.org/id/ENSGALT00010070877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043568.1", "url": "https://www.ensembl.org/id/ENSGALP00010043568.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024096", "resource": "Reactome", "description": "HS-GAG degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZ84-1", "protein_name": "N-sulfoglucosamine sulfohydrolase", "gene_name": "Sgsh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHRPAVACCLLLLVLGLYGAHSRNVLLIVADDGGFESGVYNNTAINTPHLDALARHSLIFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVQSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAFTEENSSVLQVGRNITRIKQLVRKFLQTQDDRPFFLYVALHDPHRCGHSQPQYGAFCEKFGNGESGMGRIPDWTPQIYDPQDVMVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLIIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPQRWGQVSDAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIQLTGRSLLPALEAEPPWATVFSSQSHHEVTMSYPMRSVYHQNFRLIHNLSFKMPFPIDQDFYVSPTFQDLLNRTAAGQPTGWYKNLQHYYYRERWELYDISRDPRETRNLAAEPDFAQVLEVLKAQLVKWQWETHDPWVCAPDGVLEEKLTPQCRPLHNEL", "length": 502 }, "evidence": [ { "id": "A0A8V1AHD9", "url": "https://omabrowser.org/oma/group/A0A8V1AHD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0V3V9-1", "protein_name": "3.10.1.1", "gene_name": "sgsh", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFVFAWTLLCLLLCFDVGGCRSRNVLLIIADDGGFETDVYNNTVVQTPHLRALSKRSLIFKNAFTSVSSCSPSRSTILTGLPQHQNGMYGLHQGVHHFNSFDGVQSLPLLLKRANIHTGIIGKKHVGPGPVYPFDFAYTEETNSVLQVGRNITKIKLLVRKFFQSHKEERSETKEERPFFLYVAFHDPHRCGHSQPQYGVFCEKFGNGESGMGRIPDWEPKYYSPDQVKVPYFIPDTPAARADIAAQYTTVSRLDQGIGLVLEELRKAGFENDTLVIYSSDNGIPFPNGRTNLYGSGVKEPMLLSSPEHQQRWGKLSQAYVSLLDITPTILDWFSLPYPSYSLSMSQPVELTGRSLLPALISEPSWDTVFSSQSLHEVTMFYPMRSIHKGPYRLLHNLHYRMPFPIDQDFYISPTFQDLLNRTQSGRPTGWFKTLNEYYYRQRWELFDVRTDPMEKVNLAGDLDYSEVLESLKDLLLKWQWRTEDPWVCEPDAVLEAKLEPECRPLYNGL", "length": 511 }, "evidence": [ { "id": "A0A8V1AHD9", "url": "https://omabrowser.org/oma/group/A0A8V1AHD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RZ89-1", "protein_name": "N-sulfoglucosamine sulfohydrolase", "gene_name": "SGSH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRREPVGWVLLLALGLCCAQGGRRRNVLLILADDGGFESGAYNNSAITTPHLDALARRSIVFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDRVQSLPLLLGRAGVRTGIIGKKHVGPEAVYPFDFAHTEENDSILQVGRNITRMKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGAFCEKFGNGESGMGWIPDWTPQTYNPQDVQVPYFVPDTPAARADLAAQYTTIGRMDQGIGLVLQELRGAGVLNDTLVIFTSDNGVPFPSGRTNLYWPGAAEPLLVSSPEHPQRWGQVSEAYVSLLDLTPTVLDWFSIPYPHYAIFGSKTVQLTGRSLLPALEAESLWTTVFGSQSHHEVTMSYPMRSVQHQDFRLVHNLHFRLPFPIDQDFYVSPTFQDLLNRTVAGQPTGWYKDLHRYYYRERWELYDRSRDPHETQNLAADPRYAQVLELLQTQLAKWQWDTHDPWVCAPDGVLEEKLSPQCRPLHNEL", "length": 505 }, "evidence": [ { "id": "A0A8V1AHD9", "url": "https://omabrowser.org/oma/group/A0A8V1AHD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HTF0-1", "protein_name": "N-sulphoglucosamine sulphohydrolase", "gene_name": "Sgsh", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRARGLSCCAVLLVLGLCCVHSRNVLLMVADDGGFESGAYNNSAITTPHLDALARRSLIFRNAFSSVSSCSPSRASLLTGLPQHQNGMYGLHQGVHHFNAFDKVQSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAFTEENSSVLQVGRNITRIKELVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQTYDPQDVMVPYFVPDTPAARADLAAQYTTIGRMDQGVGLVLQELQSAGVLSDTLIIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPQRWGQVSEAYVSLLDLTPTILDWFSISYPSYAIFGSKTIQLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVYHHNFRLIHNLSFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLHHYYYRERWELYDVSRDPRETQNLATDPLFSQVLEALKAQLAKWQWETHDPWVCAPDGVLEEKLSPQCRPLHNEL", "length": 502 }, "evidence": [ { "id": "A0A8V1AHD9", "url": "https://omabrowser.org/oma/group/A0A8V1AHD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P51688-1", "protein_name": "N-sulphoglucosamine sulphohydrolase", "gene_name": "SGSH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCPVPACCALLLVLGLCRARPRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSCSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNEL", "length": 502 }, "evidence": [ { "id": "A0A8V1AHD9", "url": "https://omabrowser.org/oma/group/A0A8V1AHD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VE24-1", "protein_name": "3.10.1.1", "gene_name": "Sgsh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQFLQWIFTLWLIAGCSAGPQNVLLLLADDAGFESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSPSRSQLLTGQAGHSSGMYGLHQGVHNFNVLPDTGSLPNLIRDQSGGRILSGIIGKKHVGAANNFRFDFEQTEEQHSINQIGRNITRMKEYARQFLKQAKDEKKPFFLMVGFHDPHRCGHITPQFGEFCERWGSGEEGMGSIPDWKPIYYDWRNLDVPAWLPDTDVVRQELAAQYMTISRLDQGVGLMLKELEAAGVADQTLVIYTSDNGPPFPGGRTNLYEHGIRSPLIISSPNKEDRHHEATAAMVSLLDIYPSVMDALQIPRPNDTKIVGRSILPVLREEPPIKESDSVFGSHSYHEVTMAYPMRMVRNRRYKLIHNINYWADFPIDQDFYTSPTFQQILNATLRKQTLPWYRSLLQYYQRPEWELYDIKTDPLERFNLADKAKYNGTLKQLREQLFDWQVATKDPWRCAPHAVLQEQGVYKDQPVCLTLGHEALQRPKRRILGQYEEYVVFS", "length": 524 }, "evidence": [ { "id": "A0A8V1AHD9", "url": "https://omabrowser.org/oma/group/A0A8V1AHD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "N-sulfoglucosamine sulfohydrolase activity", "id": "GO:0016250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016250", "evidence": [ { "database": "UniProtKB", "id": 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"GO:0006027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan catabolic process", "id": "GO:0030200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" } ], 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"end_pos": 401, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 487, "end_pos": 489 }, { "start_pos": 498, "end_pos": 500 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHE3-1", "uniprot_ac": "A0A8V1AHE3", "uniprot_id": "A0A8V1AHE3_CHICK", "mass": { "chemical_mass": 53406.0, "monoisotopic_mass": 53406.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "LNAAARAPAGRLQAAEITNTWPTGHVGPTGPAGCVGPARPLVSVGPAGPTGRVGPAGSAGCVGPVGPTAPVGSVGPMGAVASVGSLGPVGSLDSMGPEGSVGPVGLVGPAGPAGHVSFVGPVRPVGSVGLLGPAGPVGSVGPVRSVGHVGPVRCAGPVGCVGHVRPVECMGPVVCVPVAVGGGGPRVGWEQGKGGGRGGQPGPRGACAPPTPRTPNRGGGGGGVRPGGGGGVGGGVRGVFGVHEGCGVHGLHALNGICGVHEVHGVCGVHGGCGVDEVHGVNGICSIHEVHGVRGVFGVHEGCGVHGLHGLNGICGVHGAQRAVGSLEAVGSMGSMGSVGSMGSKGSAGFNEVHGVSGVHGGCGLYEVHGVNGICGVYGGCGVHGVNGICEVHGVQGVCGVHEVHGVFGVHGGCGVYEVHGVNGICSIHGSMEAVGPLGSVKAVGSMGSMGSMGSVGFMGSKGSVGSMQSMGSKGSMKFMEFIGSLGSMESMGSMGSVGSMESVESMRPMGSMGSVGSMGSKGSTQSVESMGSTRPVGSMRSMESVGSLGSLRLWSIWGP", "length": 560, "header": "tr|A0A8V1AHE3-1|A0A8V1AHE3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AHE3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE3/entry#A0A8V1AHE3-1", "sequence": { "sequence": "LNAAARAPAGRLQAAEITNTWPTGHVGPTGPAGCVGPARPLVSVGPAGPTGRVGPAGSAGCVGPVGPTAPVGSVGPMGAVASVGSLGPVGSLDSMGPEGSVGPVGLVGPAGPAGHVSFVGPVRPVGSVGLLGPAGPVGSVGPVRSVGHVGPVRCAGPVGCVGHVRPVECMGPVVCVPVAVGGGGPRVGWEQGKGGGRGGQPGPRGACAPPTPRTPNRGGGGGGVRPGGGGGVGGGVRGVFGVHEGCGVHGLHALNGICGVHEVHGVCGVHGGCGVDEVHGVNGICSIHEVHGVRGVFGVHEGCGVHGLHGLNGICGVHGAQRAVGSLEAVGSMGSMGSVGSMGSKGSAGFNEVHGVSGVHGGCGLYEVHGVNGICGVYGGCGVHGVNGICEVHGVQGVCGVHEVHGVFGVHGGCGVYEVHGVNGICSIHGSMEAVGPLGSVKAVGSMGSMGSMGSVGFMGSKGSVGSMQSMGSKGSMKFMEFIGSLGSMESMGSMGSVGSMESVESMRPMGSMGSVGSMGSKGSTQSVESMGSTRPVGSMRSMESVGSLGSLRLWSIWGP", "length": 560, "header": "tr|A0A8V1AHE3-1|A0A8V1AHE3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AHE3-1" }, "locus": { "chromosome": "28", "start_pos": 1518716, "end_pos": 1383058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068068.1", "url": "https://www.ensembl.org/id/ENSGALT00010068068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041811.1", "url": "https://www.ensembl.org/id/ENSGALP00010041811.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 68, "start_aa": "Thr", "end_pos": 68, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr68", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 29, 50, 68, 211 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, 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"count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJL7-1", "uniprot_ac": "A0A8V1AJL7", "uniprot_id": "A0A8V1AJL7_CHICK", "mass": { "chemical_mass": 70959.0, "monoisotopic_mass": 70959.0 }, "refseq": { "ac": "XP_004945922", "name": "carnitine O-acetyltransferase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945922" }, "gene_names": [ { "name": "CRAT", "type": "recommended", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "name": "CRAT", "type": "synonym", "evidence": [ { "id": "XP_004945922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945922" } ] } ], "protein_names": [ { "name": "Carnitine O-acetyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.137", "type": "synonym", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.7", "type": "synonym", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7/entry#names_and_taxonomy" } ] }, { "name": "Carnitine acetyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7/entry#names_and_taxonomy" } ] }, { "name": "carnitine O-acetyltransferase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004945922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945922" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945922" } ] }, { "annotation": "Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE6#function" }, { "database": "UniProtKB", "id": "ARBA00058613", "url": "https://www.uniprot.org/uniprotkb/ARBA00058613#function" }, { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRAT", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7", "locus": { "chromosome": "17", "start_pos": 6094415, "end_pos": 6110712, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028626", "url": "https://www.ensembl.org/id/ENSGALG00010028626" } ] } } ], "crossref": [ { "id": "A0A8V1AJL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "417195", "url": "https://www.ncbi.nlm.nih.gov/gene/417195", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039551", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039551", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417195", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417195", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENHSKGP", "url": "https://omabrowser.org/oma/group/ENHSKGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHE6", "url": "https://www.orthodb.org/?gene=A0A8V1AHE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJL7", "url": "https://www.orthodb.org/?gene=A0A8V1AJL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22589", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22589", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22589:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22589:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-389887", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389887", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17177", "url": "https://www.rhea-db.org/rhea/17177", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "21136", "url": "https://www.rhea-db.org/rhea/21136", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44828", "url": "https://www.rhea-db.org/rhea/44828", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44860", "url": "https://www.rhea-db.org/rhea/44860", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44972", "url": "https://www.rhea-db.org/rhea/44972", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44976", "url": "https://www.rhea-db.org/rhea/44976", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44980", "url": "https://www.rhea-db.org/rhea/44980", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44984", "url": "https://www.rhea-db.org/rhea/44984", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44988", "url": "https://www.rhea-db.org/rhea/44988", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44992", "url": "https://www.rhea-db.org/rhea/44992", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44996", "url": "https://www.rhea-db.org/rhea/44996", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45000", "url": "https://www.rhea-db.org/rhea/45000", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "45004", "url": "https://www.rhea-db.org/rhea/45004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AHE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGCVARAAARPYGLLKPAALGKIPGRFLLHQEALPHLPVPPLQQTLDRYLLTLQPIISEEELNHTQELVAEFRKPGGVGERLQKGLERRARKTENWLSDWWLKTAYLEYRLPVVVHSSPGVVLPKQDFQDRQGQLRFAAKLIEGILDFKTMIDNETLPVEYMGGKPLCMNQYYQILSSCRIPGPKRDSIVNYAKGKKQSRHITVVHNFQFFELDVYNSDGSPLTTDQIFIQLEKIWNTSLQTNKEPIGILTTNHRNSWAKAYNNLLKDKTNKESVRTIEKSICTVCLDAPMPRVSEDIYKSRVAAQMLHGGGSRWNSGNRWFDKTLQFIIAEDGSCGLVYEHAPSEGPPIVALLDHIVEYTKKPELVRSPMIPLPMPKKLRFNITPEIKNDIEKAKQNLNIMVEDLDIKVMVFHQFGKAFPKSEKISPDAFIQLALQLAYYRMYGHACPTYESASLRMFRLGRTDTIRSASIESLKFVQSMDSPDKSDQVKTDLLRRATQAHREYTDMAIRGNAIDRHLLGLKLQAIEDLVSIPELFMDTAYAVAMHFNLSTSQVPAKTDCVMCFGPVVPDGYGICYNPMDEHINFAISAFNSCADTNAARMAHYLEKALLDMRSLLQSTPKSKL", "length": 626, "header": "tr|A0A8V1AJL7-1|A0A8V1AJL7_CHICK Isoform 1 of Carnitine O-acetyltransferase OS=Gallus gallus OX=9031 GN=CRAT PE=1 SV=1 CANONICAL=A0A8V1AJL7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7/entry#A0A8V1AHE6-1", "sequence": { "sequence": "MAEPASPRSKMAVWRPRPLSAERGGGARCRRCPCGGRRRPGAEPCWAAWRGRRPLSGGRGNQDRPRESFTIISVLPAMDSKQKQAEKARPYGLLKPAALGKIPGRFLLHQEALPHLPVPPLQQTLDRYLLTLQPIISEEELNHTQELVAEFRKPGGVGERLQKGLERRARKTENWLSDWWLKTAYLEYRLPVVVHSSPGVVLPKQDFQDRQGQLRFAAKLIEGILDFKTMIDNETLPVEYMGGKPLCMNQYYQILSSCRIPGPKRDSIVNYAKGKKQSRHITVVHNFQFFELDVYNSDGSPLTTDQIFIQLEKIWNTSLQTNKEPIGILTTNHRNSWAKAYNNLLKDKTNKESVRTIEKSICTVCLDAPMPRVSEDIYKSRVAAQMLHGGGSRWNSGNRWFDKTLQFIIAEDGSCGLVYEHAPSEGPPIVALLDHIVEYTKKPELVRSPMIPLPMPKKLRFNITPEIKNDIEKAKQNLNIMVEDLDIKVMVFHQFGKAFPKSEKISPDAFIQLALQLAYYRMYGHACPTYESASLRMFRLGRTDTIRSASIESLKFVQSMDSPDKSDQVKTDLLRRATQAHREYTDMAIRGNAIDRHLLGLKLQAIEDLVSIPELFMDTAYAVAMHFNLSTSQVPAKTDCVMCFGPVVPDGYGICYNPMDEHINFAISAFNSCADTNAARMAHYLEKALLDMRSLLQSTPKSKL", "length": 704, "header": "tr|A0A8V1AHE6-1|A0A8V1AJL7_CHICK Computationally mapped isoform of Carnitine O-acetyltransferase OS=Gallus gallus OX=9031 GN=CRAT PE=1 SV=1 CANONICAL=A0A8V1AJL7-1" }, "locus": { "chromosome": "17", "start_pos": 6110513, "end_pos": 6097430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069321.1", "url": "https://www.ensembl.org/id/ENSGALT00010069321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042746.1", "url": "https://www.ensembl.org/id/ENSGALP00010042746.1" } ] } }, { "isoform_ac": "A0A8V1AJL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7/entry#A0A8V1AJL7-1", "sequence": { "sequence": "MLGCVARAAARPYGLLKPAALGKIPGRFLLHQEALPHLPVPPLQQTLDRYLLTLQPIISEEELNHTQELVAEFRKPGGVGERLQKGLERRARKTENWLSDWWLKTAYLEYRLPVVVHSSPGVVLPKQDFQDRQGQLRFAAKLIEGILDFKTMIDNETLPVEYMGGKPLCMNQYYQILSSCRIPGPKRDSIVNYAKGKKQSRHITVVHNFQFFELDVYNSDGSPLTTDQIFIQLEKIWNTSLQTNKEPIGILTTNHRNSWAKAYNNLLKDKTNKESVRTIEKSICTVCLDAPMPRVSEDIYKSRVAAQMLHGGGSRWNSGNRWFDKTLQFIIAEDGSCGLVYEHAPSEGPPIVALLDHIVEYTKKPELVRSPMIPLPMPKKLRFNITPEIKNDIEKAKQNLNIMVEDLDIKVMVFHQFGKAFPKSEKISPDAFIQLALQLAYYRMYGHACPTYESASLRMFRLGRTDTIRSASIESLKFVQSMDSPDKSDQVKTDLLRRATQAHREYTDMAIRGNAIDRHLLGLKLQAIEDLVSIPELFMDTAYAVAMHFNLSTSQVPAKTDCVMCFGPVVPDGYGICYNPMDEHINFAISAFNSCADTNAARMAHYLEKALLDMRSLLQSTPKSKL", "length": 626, "header": "tr|A0A8V1AJL7-1|A0A8V1AJL7_CHICK Isoform 1 of Carnitine O-acetyltransferase OS=Gallus gallus OX=9031 GN=CRAT PE=1 SV=1 CANONICAL=A0A8V1AJL7-1" }, "locus": { "chromosome": "17", "start_pos": 6110382, "end_pos": 6097430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069318.1", "url": "https://www.ensembl.org/id/ENSGALT00010069318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042745.1", "url": "https://www.ensembl.org/id/ENSGALP00010042745.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417195", "resource": "KEGG Pathway" }, { "id": "R-GGA-389887", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389887", "resource": "Reactome", "description": "Beta-oxidation of pristanoyl-CoA" }, { "id": "R-GGA-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZRC3-1", "protein_name": "Carnitine O-acetyltransferase", "gene_name": "CRAT", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDGQQKEKARPLGFLKPSSLTKVSSHFKTHQDSLPRLPVPPLQQTLDHYLKALQPIVSEEEWAQTKQLVEEFQSPGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPLVIYSSPGMALPKQDFVDLQGQLRFAAKLIEGVLDFKAMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDSVTNFSKIKKPPAHITVVHNYQFFELDVYHSDGTPLTSDQIFTQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYSTLIKDKVNRESVRSIQKSIFTVCLDAPMPRVSEDRYRHQVACQMLHGGGGKLNSGNRWFDKTLQFIVAEDGACGLIYEHAAAEGPPITTLVDHVIEFTKKPELVRSPMIPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVFVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMGDPNVTEHQKVELLRKAVQAHRAYTDLAICGKAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMESHINFSVSAYNSCAETNAVRLAHYLEQALLDMRALLQSHPRAKL", "length": 626 }, "evidence": [ { "id": "A0A8V1AJL7", "url": "https://omabrowser.org/oma/group/A0A8V1AJL7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IL47-1", "protein_name": "Carnitine O-acetyltransferase", "gene_name": "Crat", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLAFAARTVVKPLGLLKPSSLMKVSGRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQTPGGVGERLQKGLERRAKKMENWLSDWWLKTAYLQYRQPVVIHSSPGVMLPKQNFVDQQGQLRFAAKLIEGVLDFKSMIDNESLPVEFLGGKPLCMNQYYQILSSCRVPGPKQDSVVNFLKTKKPPMHITVVHNYQFFELDVYHSDGTPFTSDQIFVQLEKIWNSSLQTNKEPIGILTSNHRNTWAKAYNTLIKDKVNRESVNSIQKSIFTVCLDKPVPRVSDDVYRNHVAGQMLHGGGSKLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMLPMPMPKKLRFNITPEIKNDIEKAKQNISIMIQDLDITMLVFHHFGKDFPKSEKLSPDAFIQIALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSSSMDSLAFVKGMDDSTVLEHQKVELLRKAVQAHRAYTDRAIRGESFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPKAKL", "length": 626 }, "evidence": [ { "id": "A0A8V1AJL7", "url": "https://omabrowser.org/oma/group/A0A8V1AJL7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P43155-1", "protein_name": "Carnitine O-acetyltransferase", "gene_name": "CRAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSHPRAKL", "length": 626 }, "evidence": [ { "id": "A0A8V1AJL7", "url": "https://omabrowser.org/oma/group/A0A8V1AJL7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47934-1", "protein_name": "Carnitine O-acetyltransferase", "gene_name": "Crat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAFAARTVVKPLGLLKPSSLMKVSGRFKAHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAKL", "length": 626 }, "evidence": [ { "id": "A0A8V1AJL7", "url": "https://omabrowser.org/oma/group/A0A8V1AJL7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q704S8-1", "protein_name": "Carnitine O-acetyltransferase", "gene_name": "Crat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAFAARTVVKPLGLLKPSSLMKVSGRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVLLPKQDFMDLQGQLRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGLKQDSVVNFLKSKKPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNSWAKAYSSLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRSHVAGQMLHGGGSKFNSGNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEIKNDIEKAKQNISIMIQDLDIMMLVFHHFGKDFPKSQKLSPDAFIQIALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASTDSLAFVKGMDDPKVPEQQRVELLRKAVQAHRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMSFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAKL", "length": 626 }, "evidence": [ { "id": "A0A8V1AJL7", "url": "https://omabrowser.org/oma/group/A0A8V1AJL7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VEM4-1", "protein_name": "Choline/carnitine acyltransferase domain-containing protein", "gene_name": "Dmel\\CG5265", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKFRDNGKVLWNFARISALQQTRYTFGKKMPIASYSTAKDKPKSDQPNLLKYHVLPLEEILNRFMITVQPLLTPEEFKKQEKITNEFQRKEGAKLQKLLEETGEQEKNWLAHRWLKVAYLQFRSPVTCFSSPGMTFPKQKFESVHEFVDYTSRVIFGLGEFNDLVHAKKIPIVKMGKNELDNSQFGKVFGTCRIPRRFTDDIVYNPCSDYVVVIYRNHFYQLKIYDKEGKLIIAPCLAVQLEEIMAKEKEPGVPYGILTTDSRDNWAEAYEHLSNTPRNRVALKTIQNAMFTVSLDECTSPKEGRDAEELILTLIHGKGSKCNSANRWMDKTIQLVVNPNGHVGFTYEHSPAEGQPIAMMMDYVVKKMKDDPSYGECGSENFIPAKKIKFCDVSKCVEQWLIIAQKNVDKLVQDLQMKVLKFDCYGKDFIKKQRLGPDSFVQMALQLAFFKLHYEPAAQYESAHLRIFDGGRTETIRSCSNESLAFCHAMDDVSASAQERASKIREAVMCHQMYAKLALLGKGVDRHLFGLKLMAVENCLPVPEFFSSPGYVKSTHFRMSTSQVATKYDAFMGYGPSVEDGYACCYNPREHDIILAISAWRHCQATDHQKIAKALAQSFAEMKDVLETCPASKDKPPELKCKY", "length": 643 }, "evidence": [ { "id": "A0A8V1AJL7", "url": "https://omabrowser.org/oma/group/A0A8V1AJL7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "fatty acid beta-oxidation using acyl-CoA oxidase", "id": "GO:0033540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "short-chain fatty acid metabolic process", "id": "GO:0046459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "medium-chain fatty acid metabolic process", "id": "GO:0051791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "carnitine metabolic process, CoA-linked", "id": "GO:0019254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "acyl-CoA oxidase activity", "id": "GO:0003997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003997", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "carnitine O-octanoyltransferase activity", "id": "GO:0008458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008458", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" }, { "name": "carnitine O-acetyltransferase activity", "id": "GO:0004092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17177", "name": "", "equation": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZWG4-1", "A0A8V0XIT0-1", "A0A8V1AJL7-1" ], "evidence": [ { "id": "17177", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17177" } ] }, { "id": "21136", "name": "", "equation": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "21136", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21136" } ] }, { "id": "44828", "name": "", "equation": "decanoyl-CoA + (R)-carnitine = O-decanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZWG4-1", "A0A8V1AJL7-1" ], "evidence": [ { "id": "44828", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44828" } ] }, { "id": "44860", "name": "", "equation": "4,8-dimethylnonanoyl-CoA + (R)-carnitine = O-4,8-dimethylnonanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZWG4-1", "A0A8V0XIT0-1", "A0A8V1AJL7-1" ], "evidence": [ { "id": "44860", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44860" } ] }, { "id": "44972", "name": "", "equation": "hexanoyl-CoA + (R)-carnitine = O-hexanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "44972", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44972" } ] }, { "id": "44976", "name": "", "equation": "propanoyl-CoA + (R)-carnitine = O-propanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "44976", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44976" } ] }, { "id": "44980", "name": "", "equation": "butanoyl-CoA + (R)-carnitine = O-butanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "44980", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44980" } ] }, { "id": "44984", "name": "", "equation": "3-methylbutanoyl-CoA + (R)-carnitine = O-3-methylbutanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "44984", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44984" } ] }, { "id": "44988", "name": "", "equation": "2-methylpropanoyl-CoA + (R)-carnitine = O-isobutanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "44988", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44988" } ] }, { "id": "44992", "name": "", "equation": "2-methylbutanoyl-CoA + (R)-carnitine = O-2-methylbutanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "44992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44992" } ] }, { "id": "44996", "name": "", "equation": "acetoacetyl-CoA + (R)-carnitine = O-3-oxobutanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "44996", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44996" } ] }, { "id": "45000", "name": "", "equation": "3-hydroxybutanoyl-CoA + (R)-carnitine = O-3-hydroxybutanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "45000", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45000" } ] }, { "id": "45004", "name": "", "equation": "2,6-dimethylheptanoyl-CoA + (R)-carnitine = O-2,6-dimethylheptanoyl-(R)-carnitine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "45004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/45004" } ] }, { "id": "R-GGA-390284", "name": "propionyl-CoA + carnitine => propionylcarnitine + CoASH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-390294" ], "output_participant_list": [ "R-ALL-390274" ], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "R-GGA-390284", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390284" } ] }, { "id": "R-GGA-390291", "name": "acetyl-CoA + carnitine => acetylcarnitine + CoASH", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-390287" ], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "R-GGA-390291", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390291" } ] }, { "id": "R-GGA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033235" } ] }, { "id": "R-GGA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033236" } ] }, { "id": "R-GGA-9971123", "name": "CRAT transfers ISB to CAR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-9971124" ], "enzyme_list": [ "A0A8V1AJL7-1" ], "evidence": [ { "id": "R-GGA-9971123", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9971123" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-390274", "participant_name": "Propionylcarnitine [peroxisomal matrix]", "crossref": [ { "id": "HMDB0000824", "database": "HMDB Metabolite", "url": "" }, { "id": "53210", "database": "ChEBI", "url": "" }, { "id": "ZINC000001529576", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-390287", "participant_name": "ACAR [peroxisomal matrix]", "crossref": [ { "id": "4520", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "HMDB0000201", "database": "HMDB Metabolite", "url": "" }, { "id": "57589", "database": "ChEBI", "url": "" }, { "id": "ZINC000003644165", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-390294", "participant_name": "CAR [peroxisomal matrix]", "crossref": [ { "id": "16347", "database": "ChEBI", "url": "" }, { "id": "C00318", "database": "COMPOUND", "url": "" }, { "id": "4780", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003079340", "database": "ZINC", "url": "" }, { "id": "HMDB0000062", "database": "HMDB Metabolite", "url": "" }, { "id": "C00487", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-9971124", "participant_name": "ISB-CAR [mitochondrial matrix]", "crossref": [ { "id": "HMDB0000736", "database": "HMDB Metabolite", "url": "" }, { "id": "84838", "database": "ChEBI", "url": "" }, { "id": "ZINC000005359087", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5PZB7", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] } ] }, { "uniprot_ac": "A0A1L1RJ90", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] } ] }, { "uniprot_ac": "A0A8V0XEK2", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] } ] }, { "uniprot_ac": "A0A8V0XIT0", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] } ] }, { "uniprot_ac": "A0A8V0XXY0", "gene_name": "MLYCD", "activity": [ { "ec_number": "4.1.1.9", "activity": "malonyl-CoA + H(+) = acetyl-CoA + CO2.", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] }, { "ec_number": "4.1.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] } ] }, { "uniprot_ac": "A0A8V0Y1Q3", "gene_name": "NUDT7", "activity": [ { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] } ] }, { "uniprot_ac": "A0A8V0Y2T0", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] } ] }, { "uniprot_ac": "A0A8V0YAP6", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] } ] }, { "uniprot_ac": "A0A8V0YMJ0", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZC97", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] } ] }, { "uniprot_ac": "A0A8V0ZI42", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] } ] }, { "uniprot_ac": "A0A8V0ZIT7", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] } ] }, { "uniprot_ac": "A0A8V0ZLD0", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZLD0", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A8V0ZWG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWG4" } ] } ] }, { "uniprot_ac": "A0A8V1A097", "gene_name": "HAO2", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] } ] }, { "uniprot_ac": "A0A8V1A124", "gene_name": "AGXT", "activity": [ { "ec_number": "2.6.1.51", "activity": "L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V1A124", "database": 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4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] } ] }, { "uniprot_ac": "A0A8V1A8Z1", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] } ] }, { "uniprot_ac": "A0A8V1AJL7", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] } ] }, { "uniprot_ac": "A0A8V1ANC5", "gene_name": "PIPOX", "activity": [ { "ec_number": "1.5.3.1", "activity": "sarcosine + O2 + H2O = formaldehyde + glycine + H2O2.", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "L-pipecolate + O2 = L-1-piperideine-6-carboxylate + H2O2 + H(+).", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.1", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] } ] }, { "uniprot_ac": "E1BRR7", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] } ] }, { "uniprot_ac": "F1N9G6", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] } ] }, { "uniprot_ac": "F1NG68", "gene_name": "DECR2", "activity": [ { "ec_number": "1.3.1.124", "activity": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] }, { "ec_number": "1.3.1.124", "activity": "", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] } ] }, { "uniprot_ac": "F1NKY1", "gene_name": "AMACR", "activity": [ { "ec_number": "5.1.99.4", "activity": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] }, { "ec_number": "5.1.99.4", "activity": "", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] } ] }, { "uniprot_ac": "Q5ZL13", "gene_name": "NUDT19", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" }, { "id": "PF00755", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00755" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Choline/carnitine acyltransferase", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 609, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.137", "ec_name": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "2.3.1.137", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.137" }, { "id": "2.3.1.137", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.137" } ] }, { "ec_number": "2.3.1.7", "ec_name": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "2.3.1.7", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.7" }, { "id": "2.3.1.7", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.7" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHF1-1", "uniprot_ac": "A0A8V1AHF1", "uniprot_id": "A0A8V1AHF1_CHICK", "mass": { "chemical_mass": 56767.0, "monoisotopic_mass": 56767.0 }, "refseq": { "ac": "XP_024999300", "name": "tetratricopeptide repeat protein 24", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999300" }, "gene_names": [ { "name": "TTC24", "type": "recommended", "evidence": [ { "id": "A0A8V1AHF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1" } ] }, { "name": "TTC24", "type": "synonym", "evidence": [ { "id": "XP_024999300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999300" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat domain 24", "type": "synonym", "evidence": [ { "id": "A0A8V1AHF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 24", "type": "synonym", "evidence": [ { "id": "XP_024999300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999300" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999300.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999300" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC24", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1", "locus": { "chromosome": "25", "start_pos": 434788, "end_pos": 439294, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028097", "url": "https://www.ensembl.org/id/ENSGALG00010028097" } ] } } ], "crossref": [ { "id": "A0A8V1AHF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747902", "url": "https://www.ncbi.nlm.nih.gov/gene/101747902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747902", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASSCPMF", "url": "https://omabrowser.org/oma/group/ASSCPMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF09", "url": "https://www.orthodb.org/?gene=A0A8V1AF09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHF1", "url": "https://www.orthodb.org/?gene=A0A8V1AHF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47050:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47050:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999300", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AF09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHTGTWRTPRCSPHSRWLSSPLPMASEEPTTPPAPAAPGRKRRRKGKEKPILGEGDNAEDGDDGAGRVAEIEGLTRAGCRALGLGDTRGALGCFRRAVGLSLRTPTPRLRRDCAFRLGAAYVEAGKPRKGLKFLLKSQPSDGERPEGLRFDVAAAHEGLRDFPEDLRGSGGAAPRAGSSAVMGCCYLGMREPDRAARCFLEAARGYAGIHRPEAAAVALSRASGSMLQSGRFGAAEVAGTLAQCRALCDSIPDPTLQGKLYNDIGLGYSQLRIFPLAAESFERALTACRGAPGCSGEAAVLQNLGAARNALRRFNAALAPHRRAAALHGAAGNRRAQGQCFGNLAYAFSQLGEHEAAAENYLHALQAFRDSGDVHGQCKACEGLGAARFHLGDPQRAVGHYQEALRLLSRCQGTPRADGERIVTELTRTLQLQLCLRPTPALDLVPLQFCSPLPHISGTQLRGRTVSFRDTARGGGEAAQGDPPRGSAPKLRHPPALPPSIPAVIALRAAPEPPRSTRAGPGGRGGCTVLSQLCSLL", "length": 538, "header": "tr|A0A8V1AHF1-1|A0A8V1AHF1_CHICK Isoform 1 of Tetratricopeptide repeat domain 24 OS=Gallus gallus OX=9031 GN=TTC24 PE=4 SV=1 CANONICAL=A0A8V1AHF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1/entry#A0A8V1AF09-1", "sequence": { "sequence": "MASEEPTTPPAPAAPGRKRRRKGKEKPILGEGDNAEDGDDGAGRVAEIEGLTRAGCRALGLGDTRGALGCFRRAVGLSLRTPTPRLRRDCAFRLGAAYVEAGKPRKGLKFLLKSQPSDGERPEGLRFDVAAAHEGLRDFPEDLRGSGGAAPRAGSSAVMGCCYLGMREPDRAARCFLEAARGYAGIHRPEAAAVALSRASGSMLQSGRFGAAEVAGTLAQCRALCDSIPDPTLQGKLYNDIGLGYSQLRIFPLAAESFERALTACRGAPGCSGEAAVLQNLGAARNALRRFNAALAPHRRAAALHGAAGNRRAQGQCFGNLAYAFSQLGEHEAAAENYLHALQAFRDSGDVHGQCKACEGLGAARFHLGDPQRAVGHYQEALRLLSRCQGTPRADGERIVTELTRTLQLQLCLRPTPALDLVPLQFCSPLPHISGTQLRGRTVSFRDTARGGGEAAQGDPPRGSAPKLRHPPALPPSIPAVIALRAAPEPPRSTRAGPGGRGGCTVLSQLCSLL", "length": 514, "header": "tr|A0A8V1AF09-1|A0A8V1AF09_CHICK Computationally mapped isoform of Tetratricopeptide repeat domain 24 OS=Gallus gallus OX=9031 GN=TTC24 PE=4 SV=1 CANONICAL=A0A8V1AHF1-1" }, "locus": { "chromosome": "25", "start_pos": 438317, "end_pos": 435173, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068080.1", "url": "https://www.ensembl.org/id/ENSGALT00010068080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041823.1", "url": "https://www.ensembl.org/id/ENSGALP00010041823.1" } ] } }, { "isoform_ac": "A0A8V1AHF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF1/entry#A0A8V1AHF1-1", "sequence": { "sequence": "MGHTGTWRTPRCSPHSRWLSSPLPMASEEPTTPPAPAAPGRKRRRKGKEKPILGEGDNAEDGDDGAGRVAEIEGLTRAGCRALGLGDTRGALGCFRRAVGLSLRTPTPRLRRDCAFRLGAAYVEAGKPRKGLKFLLKSQPSDGERPEGLRFDVAAAHEGLRDFPEDLRGSGGAAPRAGSSAVMGCCYLGMREPDRAARCFLEAARGYAGIHRPEAAAVALSRASGSMLQSGRFGAAEVAGTLAQCRALCDSIPDPTLQGKLYNDIGLGYSQLRIFPLAAESFERALTACRGAPGCSGEAAVLQNLGAARNALRRFNAALAPHRRAAALHGAAGNRRAQGQCFGNLAYAFSQLGEHEAAAENYLHALQAFRDSGDVHGQCKACEGLGAARFHLGDPQRAVGHYQEALRLLSRCQGTPRADGERIVTELTRTLQLQLCLRPTPALDLVPLQFCSPLPHISGTQLRGRTVSFRDTARGGGEAAQGDPPRGSAPKLRHPPALPPSIPAVIALRAAPEPPRSTRAGPGGRGGCTVLSQLCSLL", "length": 538, "header": "tr|A0A8V1AHF1-1|A0A8V1AHF1_CHICK Isoform 1 of Tetratricopeptide repeat domain 24 OS=Gallus gallus OX=9031 GN=TTC24 PE=4 SV=1 CANONICAL=A0A8V1AHF1-1" }, "locus": { "chromosome": "25", "start_pos": 438703, "end_pos": 435173, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068079.1", "url": "https://www.ensembl.org/id/ENSGALT00010068079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041822.1", "url": "https://www.ensembl.org/id/ENSGALP00010041822.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 440, "start_aa": "Thr", "end_pos": 440, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr440", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101747902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747902", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A3L6-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "TTC24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSPNPEDVPRRPEPEPSSSNKKKKKRKWLRQEASIQALTRAGHGALQAGQNHEALNNFQRAFLLASKAPQTRDTPVLQACAFNLGAAYVETGDPARGLELLLRAHPEEKAQGRRHGDQCFNVALAYHALGELPQALAWYHRALGHYQPQGDQGEAWAKMGACYQALGQPELAAHCLQEASQAYAQERQLRAAALALGAAAGCMLKSGRHRVGEVVQVLEKSRRLAERSTERRLLGHLYNDLGLGYSQLQLFPLAVEAFLQALPLCWVPGEQATVLRNLGMAHNALGNYQEAREFHQKAADLHGSVGQRWEQGRSFGSLAFALSQLGDHKAARDNYLHALQAARDSGDMKGQWQACEGLGAAAARLGQYDQALKYYKEALAQCQKEPDSVRERLVAKLADTVRTRLAQVGLVQTHTLTSAPGRLQAPGGASQAEGTPAKAGSSTAGVQHRSSSGWEDEEFEEGHQKKKEERSANVPVRAGPGRPELCFLPGTVNHSHHLASSCPTFTKHTPCRGTVLGKASIYSPGPRAHLPFVGPGPPRAEYPSILVPNGPQANRSSRWPRESLSRSRQRRPMESGICTIV", "length": 582 }, "evidence": [ { "id": "A0A8V1AHF1", "url": "https://omabrowser.org/oma/group/A0A8V1AHF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1LUG6-1", "protein_name": "Tetratricopeptide repeat domain 24", "gene_name": "Ttc24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSSRQYRLSEVLQALEESRKLADADRGADQGLLGPFYNDVGMGYFQLQLFPLAVEAFLQALPLCRQAAEQATVLQNLGMTHNVLGNYWEAQEFHQKAVDLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSIRERLVAKLADATRTFVTQEKLAQAHFLPSVPGKLQTSWEASLEAKNSARVHSSAEDAQDSRSEEGREKKKEGLMNMTIVLEPQRQDCLGASEHLPSGGPWPRGVEHLVNTAPNNRSSIGTKEALGRNLQRTSIQSGLCTIV", "length": 330 }, "evidence": [ { "id": "A0A8V1AHF1", "url": "https://omabrowser.org/oma/group/A0A8V1AHF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 440 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJM1-1", "uniprot_ac": "A0A8V1AJM1", "uniprot_id": "A0A8V1AJM1_CHICK", "mass": { "chemical_mass": 45104.0, "monoisotopic_mass": 45104.0 }, "refseq": {}, "gene_names": [ { "name": "LOC101751615", "type": "recommended", "evidence": [ { "id": "A0A8V1AJM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AJM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101751615", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJM1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00099", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00099", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9W3", "url": "https://www.orthodb.org/?gene=A0A8V1A9W3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHF4", "url": "https://www.orthodb.org/?gene=A0A8V1AHF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJM1", "url": "https://www.orthodb.org/?gene=A0A8V1AJM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14334:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14334:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9W3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAERAAPLSTWGGGDGVGAASLLSFPNLCPLPEVPPSPLCAPRCPPGASSHRHCHLSHNLGCRMRHRKAPPRPRGPVPPQIPHSERSARAESSLEPFSCAQRHPSMPCSPAAVVLLLLLPGAARAQLRIRQSPAQLWVRPGRTAELNCSTDSGWNVDRHRAVSWYREQPGSRLQFIYPSPDSSRSEGKYSQMRRAKGLFSFYINSAQREDSGFYYCASTSEPFEFGDGTRLVVTDATEPTLSILLPLDAELREPPRAAIPLLCHLYDAPKGWDTVRWHHGNVSPVTATSMDGRGVLSAWSLTWLTAEQWDGTVGCTAVQSSTGRTITVTIRQPSSTAQCLQWLPVVLLPSVLTIAVQLMLQLCRKTHTGGPGAPQPPQQCRHPRPSHRAAGWSQETEYAMVALRAPSPRVQ", "length": 412, "header": "tr|A0A8V1AJM1-1|A0A8V1AJM1_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751615 PE=4 SV=1 CANONICAL=A0A8V1AJM1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1/entry#A0A8V1A9W3-1", "sequence": { "sequence": "MRHRKAPPRPRGPVPPQIPHSERSARAESSLEPFSCAQRHPSMPCSPAAVVLLLLLPGAARAQLRIRQSPAQLWVRPGRTAELNCSTDSGWNVDRHRAVSWYREQPGSRLQFIYPSPDSSRSEGKYSQMRRAKGLFSFYINSAQREDSGFYYCASTSEPFEFGDGTRLVVTDATEPTLSILLPLDAELREPPRAAIPLLCHLYDAPKGWDTVRWHHGNVSPVTATSMDGRGVLSAWSLTWLTAEQWDGTVGCTAVQSSTGRTITVTIRQPSSTAQCLQWLPVVLLPSVLTIAVQLMLQLCRKTHTGGPGAPQPPQQCRHPRPSHRAAGWSQEEILREEKRK", "length": 341, "header": "tr|A0A8V1A9W3-1|A0A8V1A9W3_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751615 PE=4 SV=1 CANONICAL=A0A8V1AJM1-1" }, "locus": { "chromosome": "25", "start_pos": 2332297, "end_pos": 2323502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069362.1", "url": "https://www.ensembl.org/id/ENSGALT00010069362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042752.1", "url": "https://www.ensembl.org/id/ENSGALP00010042752.1" } ] } }, { "isoform_ac": "A0A8V1AHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1/entry#A0A8V1AHF4-1", "sequence": { "sequence": "MRHRKAPPRPRGPVPPQIPHSERSARAESSLEPFSCAQRHPSMPCSPAAVVLLLLLPGAARAQLRIRQSPAQLWVRPGRTAELNCSTDSGWNVDRHRAVSWYREQPGSRLQFIYPSPDSSRSEGKYSQMRRAKGLFSFYINSAQREDSGFYYCASTSEPFEFGDGTRLVVTDATEPTLSILLPLDAELREPPRAAIPLLCHLYDAPKGWDTVRWHHGNVSPVTATSMDGRGVLSAWSLTWLTAEQWDGTVGCTAVQSSTGRTITVTIRQPSSTAQCLQWLPVVLLPSVLTIAVQLMLQLCRKTHTGGPGAPQPPQQCRHPRPSHRAAGWSQETEYAMVALRAPSPRVQ", "length": 348, "header": "tr|A0A8V1AHF4-1|A0A8V1AJM1_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751615 PE=4 SV=1 CANONICAL=A0A8V1AJM1-1" }, "locus": { "chromosome": "25", "start_pos": 2326386, "end_pos": 2323502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069360.1", "url": "https://www.ensembl.org/id/ENSGALT00010069360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042751.1", "url": "https://www.ensembl.org/id/ENSGALP00010042751.1" } ] } }, { "isoform_ac": "A0A8V1AJM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1/entry#A0A8V1AJM1-1", "sequence": { "sequence": "MRAERAAPLSTWGGGDGVGAASLLSFPNLCPLPEVPPSPLCAPRCPPGASSHRHCHLSHNLGCRMRHRKAPPRPRGPVPPQIPHSERSARAESSLEPFSCAQRHPSMPCSPAAVVLLLLLPGAARAQLRIRQSPAQLWVRPGRTAELNCSTDSGWNVDRHRAVSWYREQPGSRLQFIYPSPDSSRSEGKYSQMRRAKGLFSFYINSAQREDSGFYYCASTSEPFEFGDGTRLVVTDATEPTLSILLPLDAELREPPRAAIPLLCHLYDAPKGWDTVRWHHGNVSPVTATSMDGRGVLSAWSLTWLTAEQWDGTVGCTAVQSSTGRTITVTIRQPSSTAQCLQWLPVVLLPSVLTIAVQLMLQLCRKTHTGGPGAPQPPQQCRHPRPSHRAAGWSQETEYAMVALRAPSPRVQ", "length": 412, "header": "tr|A0A8V1AJM1-1|A0A8V1AJM1_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC101751615 PE=4 SV=1 CANONICAL=A0A8V1AJM1-1" }, "locus": { "chromosome": "25", "start_pos": 2326386, "end_pos": 2323310, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069358.1", "url": "https://www.ensembl.org/id/ENSGALT00010069358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042750.1", "url": "https://www.ensembl.org/id/ENSGALP00010042750.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 235, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 282, "end_pos": 284 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHF9-1", "uniprot_ac": "A0A8V1AHF9", "uniprot_id": "A0A8V1AHF9_CHICK", "mass": { "chemical_mass": 66810.0, "monoisotopic_mass": 66810.0 }, "refseq": { "ac": "XP_003642326", "name": "inactive glycosyltransferase 25 family member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642326" }, "gene_names": [ { "name": "CERCAM", "type": "recommended", "evidence": [ { "id": "A0A8V1AHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9" } ] }, { "name": "CERCAM", "type": "synonym", "evidence": [ { "id": "XP_003642326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642326" } ] } ], "protein_names": [ { "name": "Cerebral endothelial cell adhesion molecule", "type": "synonym", "evidence": [ { "id": "A0A8V1AHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9/entry#names_and_taxonomy" } ] }, { "name": "inactive glycosyltransferase 25 family member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003642326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642326" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642326.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642326" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CERCAM", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9", "locus": { "chromosome": "17", "start_pos": 5609828, "end_pos": 5614584, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028102", "url": "https://www.ensembl.org/id/ENSGALG00010028102" } ] } } ], "crossref": [ { "id": "A0A8V1AHF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06532", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06532", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427768", "url": "https://www.ncbi.nlm.nih.gov/gene/427768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427768", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427768", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEVHVCN", "url": "https://omabrowser.org/oma/group/VEVHVCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHF9", "url": "https://www.orthodb.org/?gene=A0A8V1AHF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10730:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10730:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPLRCAALVLLLLLLLGTGTGTGTGGSPEPPRVVLALLARNAQHSLPHCLGALESLDFPAGNIALWCATDHNSDNTTAMLQEWLQAVGSNYHSVAWKAEEGPSSYPDELSPKHWSDKRYENLMRLKQEALSYARGLRADYILFVDTDSILTNNQTLTFLMAQNKSVVAPMLDSQTFYSNFWCGITPQGFYRRTADYFPTKNRQRRGCFAVPMVYATFLIDLRKEETAQLAFYPPHPNYTWAFDDIIVFAYSCQEAGAEVHVCNQQRFGYINVPVKAHQTLEDERVNFVHLTLEAMVDGPPMQRSRHISVPPKPLTKLGFDEIFLINLVRRPDRRRRMLESLQELEITARVVDAVDGSTLNSSDIKVLGVDLLPGYYDPFSGRTLTKGEVGCFLSHYNIWKEIVSQGLERVLVFEDDVRFEVSFPARLQQLMEELEEARHDWDLIYLGRKQVNAEDEAPVEGVQNLVVAGYSYWTLAYAISLRGAQKLLAAKPLSKMLPVDEFLPIMYDKHPNEDYKRHFAPRDLQVFSAHPLLVYPTHYAGDSNWLSDTETSTIWDDDSKQTGWVGSQKTLRDPRDGGGYLRSASHDEF", "length": 590, "header": "tr|A0A8V1AHF9-1|A0A8V1AHF9_CHICK Isoform 1 of Cerebral endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=CERCAM PE=3 SV=1 CANONICAL=A0A8V1AHF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9/entry#A0A8V1AHF9-1", "sequence": { "sequence": "MGPLRCAALVLLLLLLLGTGTGTGTGGSPEPPRVVLALLARNAQHSLPHCLGALESLDFPAGNIALWCATDHNSDNTTAMLQEWLQAVGSNYHSVAWKAEEGPSSYPDELSPKHWSDKRYENLMRLKQEALSYARGLRADYILFVDTDSILTNNQTLTFLMAQNKSVVAPMLDSQTFYSNFWCGITPQGFYRRTADYFPTKNRQRRGCFAVPMVYATFLIDLRKEETAQLAFYPPHPNYTWAFDDIIVFAYSCQEAGAEVHVCNQQRFGYINVPVKAHQTLEDERVNFVHLTLEAMVDGPPMQRSRHISVPPKPLTKLGFDEIFLINLVRRPDRRRRMLESLQELEITARVVDAVDGSTLNSSDIKVLGVDLLPGYYDPFSGRTLTKGEVGCFLSHYNIWKEIVSQGLERVLVFEDDVRFEVSFPARLQQLMEELEEARHDWDLIYLGRKQVNAEDEAPVEGVQNLVVAGYSYWTLAYAISLRGAQKLLAAKPLSKMLPVDEFLPIMYDKHPNEDYKRHFAPRDLQVFSAHPLLVYPTHYAGDSNWLSDTETSTIWDDDSKQTGWVGSQKTLRDPRDGGGYLRSASHDEF", "length": 590, "header": "tr|A0A8V1AHF9-1|A0A8V1AHF9_CHICK Isoform 1 of Cerebral endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=CERCAM PE=3 SV=1 CANONICAL=A0A8V1AHF9-1" }, "locus": { "chromosome": "17", "start_pos": 5614557, "end_pos": 5610278, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068089.1", "url": "https://www.ensembl.org/id/ENSGALT00010068089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041832.1", "url": "https://www.ensembl.org/id/ENSGALP00010041832.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427768", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427768", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KGW5-1", "protein_name": "Inactive glycosyltransferase 25 family member 3", "gene_name": "Cercam", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHVARLLPLLLLLGQQLRAASVTEPTLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNMDNTTGMLREWLAAVGRDYATVVWKPEEEARSYPDEQGPKHWTKERHQFLMELRQEALAFARDWGADYILFADTDNILTNNQTLKLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLLSLQTEETARLAFYPPHPNYSWPFDDIIVFAYACQAAGVSMHVCNDHRYGYMNVVVKPHQSLEEEKTNFIHLILEALVDGPPMLASAHVSRPPKKLSKMGFDEVFVISLARRPQRRARMLSSLWEMEISAQVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGHTLTKGEVGCFLSHYSIWEEVVARGLARVVVFEDDVRFKDNFRRRLERLMEDVLIQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAYFWPRDLQAFSARPLLASPTHYSGDAEWLSDTETSSPWDDDSGRLISQTGSQKALRGPHLHLTGSSGHSLHPHHRDEL", "length": 592 }, "evidence": [ { "id": "A0A8V1AHF9", "url": "https://omabrowser.org/oma/group/A0A8V1AHF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7MB73-1", "protein_name": "Probable inactive glycosyltransferase 25 family member 3", "gene_name": "CERCAM", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRAAPAAPLLQLLLLLGPRPEAAGVAEPPLPTVVLAILARNAEHSLPHYLGALERLDYPRARLALWCATDHNVDNTTAMLREWLAAVGDNYAAVVWRPEGEPRSYPDEEGPKHWTKERHQFLMELKQEALTFARDWGADYILFADTDNILTNNQTLRLLIEPGLPVVAPMLDSQTYYSNFWCGITPQGYYRRTADYFPTKNRQRRGCFRVPMVHSTFLVSLRAEGTGQLAFYPPHPNYTWPFDDIIVFAYACQAAGVAVHVCNEQRYGYLNVPVKSHQGLEDERVNFIHLILEALVDGPPMWASAHVSRPPKRPSKMGFDEVFVISLARRPDRRERMLTSLWEMEISGRVVDAVDGRMLNSSVMRTLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVTRGLAQVVVFEDDVRFESNFKGRLEQLMEEVEAEKLPWDLIYLGRKQVNPEEEAVVEGLPHLVAAGYSYWTLAYVLSLAGARKLLASQPLRRMLPVDEFLPIMFDQHPNEQYKAHFWPRDLQAFSARPLLAAPTHYAGDSEWLSDTETSSPWDDDSGRLISWTGSYKTLRGPRLDLAGGSGHSLRPHPRDEL", "length": 595 }, "evidence": [ { "id": "A0A8V1AHF9", "url": "https://omabrowser.org/oma/group/A0A8V1AHF9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RR83-1", "protein_name": "Cerebral endothelial cell adhesion molecule", "gene_name": "CERCAM", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAAPAAPLLQLLLLLGPRLQAAGIAEPPLPTVVLVILARNAEHSLPHYLGALERLDYPRARLALWCATDHNEDSTTEMLQEWLAAVGEDYAAVVWRPEGEPRSYPDEEGPKHWTKERHQFLMELKQEALTFARDWGADYILFADTDNILTNNQTLRLLIEQQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRRGCFRVPMVHSTFLISLRAEGTGQLSFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNEHRYGYMNVPVKSHQGLEDERVNFIHLLLEALVDGPPMWASAHVSRPPKRPSKMGFDEVFVISLARRPDRRERMLSSLWEMEIAGRVVDAVDGRMLNSSVMRRLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVAQGLAQVVVFEDDVRFESNFRGRLERLMEEVEAEKLPWDLIYLGRKQVNPEEEAAVEGLPQLVVAGYSYWTLAYVLSLAGARKLLASQPLRRMLPVDEFLPIMFDQHPNEQYKAHFWPRDLRAFSARPLLAAPTHYAGDAEWLSDTETSSPWDDDSGRLISWSGSYKTLRDPRLDLAGSSGHSLHPRPQDEL", "length": 595 }, "evidence": [ { "id": "A0A8V1AHF9", "url": "https://omabrowser.org/oma/group/A0A8V1AHF9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5T4B2-1", "protein_name": "Inactive glycosyltransferase 25 family member 3", "gene_name": "CERCAM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAARAAPLLQLLLLLGPWLEAAGVAESPLPAVVLAILARNAEHSLPHYLGALERLDYPRARMALWCATDHNVDNTTEMLQEWLAAVGDDYAAVVWRPEGEPRFYPDEEGPKHWTKERHQFLMELKQEALTFARNWGADYILFADTDNILTNNQTLRLLMGQGLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRRGCFRVPMVHSTFLASLRAEGADQLAFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNEHRYGYMNVPVKSHQGLEDERVNFIHLILEALVDGPRMQASAHVTRPSKRPSKIGFDEVFVISLARRPDRRERMLASLWEMEISGRVVDAVDGWMLNSSAIRNLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVARGLARVLVFEDDVRFESNFRGRLERLMEDVEAEKLSWDLIYLGRKQVNPEKETAVEGLPGLVVAGYSYWTLAYALRLAGARKLLASQPLRRMLPVDEFLPIMFDQHPNEQYKAHFWPRDLVAFSAQPLLAAPTHYAGDAEWLSDTETSSPWDDDSGRLISWSGSQKTLRSPRLDLTGSSGHSLQPQPRDEL", "length": 595 }, "evidence": [ { "id": "A0A8V1AHF9", "url": "https://omabrowser.org/oma/group/A0A8V1AHF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U309-1", "protein_name": "Probable inactive glycosyltransferase 25 family member 3", "gene_name": "Cercam", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFIIRARACGGDARSWKQPDQLHPILFTNLRLPLQLIASSAGGATDHNVDNTTGMLQEWLAAVGRDYATVVWKSEDEARSYPDEQGPKHWTRERHQFLMELKQEALAFARDWGADYILFADTDNILTNNQTLRLLIDRQLPVVAPMLDSQTYYSNFWCGITPQGYYRRTAEYFPTKNRQRQGCFRVPMVHSTFLVSLQTEETARLAFYPPHPNYTWPFDDIIVFAYACQAAGVSVHVCNDHRYGYMNVGVKPHQGLEEEKTNFIHLILEALVDGPPMMASAHVSRPPKKPSKMGFDEVFVISLARRPQRRARMLSSLWEMEISARVVDAVDGRTLNSSILKHLGVDLLPGYQDPYSGRTLTKGEVGCFLSHYSIWEEVVAKGLARVVVFEDDVRFEDNFRKRLERLMEDVLTQKLSWDLIYLGRKQVNPEEEVAVEGLPGLVVAGYSYWTLAYTLSLAGARKLLASQPLHRMLPVDEFLPVMFDRHPNDQYKAHFWPRDLQAFSARPLLASPTHYAGDTEWLSDTETSSPWDDDSGRLISWTGSQKTLRGPYLHLAGSSGHSLHPHPRDEL", "length": 572 }, "evidence": [ { "id": "A0A8V1AHF9", "url": "https://omabrowser.org/oma/group/A0A8V1AHF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF9" }, { "id": "PF01755", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01755" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl transferase family 25", "eco_id": "ECO_0000259", "start_pos": 321, "end_pos": 503, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHG1-1", "uniprot_ac": "A0A8V1AHG1", "uniprot_id": "A0A8V1AHG1_CHICK", "mass": { "chemical_mass": 62079.0, "monoisotopic_mass": 62079.0 }, "refseq": { "ac": "XP_040508271", "name": "Fc receptor-like 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508271" }, "gene_names": [ { "name": "FCRL4", "type": "recommended", "evidence": [ { "id": "A0A8V1AHG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1" } ] }, { "name": "FCR/L", "type": "synonym", "evidence": [ { "id": "XP_040508271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508271" } ] }, { "name": "FCRL2", "type": "synonym", "evidence": [ { "id": "XP_040508271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508271" } ] }, { "name": "FCRL4", "type": "synonym", "evidence": [ { "id": "XP_040508271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508271" } ] } ], "protein_names": [ { "name": "Fc receptor like 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AHG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1/entry#names_and_taxonomy" } ] }, { "name": "Fc receptor-like 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040508271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040508271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FCRL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1", "locus": { "chromosome": "25", "start_pos": 2335836, "end_pos": 2342953, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028662", "url": "https://www.ensembl.org/id/ENSGALG00010028662" } ] } } ], "crossref": [ { "id": "A0A8V1AHG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHG1", "database": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871809", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871809", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871837", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871837", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040508271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040508271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9X3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGWPLRSMGHLLLVLLWDMPGEGLDLLGEGDMFAYPVWLRGLGWSSGRPITIQAQGFLCRMVAGNAGQERNWGPARLAGMSTVRVGMLCHGVVGGARRCLGTWQTITKSHRPNDGSPPRAGSCRRPGSVGWSFSPHLFLLLAAQALSLAVAEMALLTMDPPWSVIFQGESVTLRCQGPPVHKQQPTAWYHNGKLLEHTETNTYRIQNARYKQNGRYECQSPGSTSSNSVTLSVSYDLLILQVPSHAVFEGELLQMQCRGWKVGSLAAVRFYRDGADITKPYTSAMQLSIPQAKAHHSGRYHCSADMHSYLSLKRRESQGLYISIKELFTSPVLSVASSAEPLEGSPLNLSCITQLSPYRPHTVLWYLFYGNSTVLQGPVTSSEYQVPAVGLMDTGFYSCAVRTESSNVQKWSPRVPITIKRVPISGVSLEVWPQEGQVMEGHRLVLHCSVATGTGSISFSWHREGSAEVLGRDSRYEIPSTQQSDNGQYYCMASNGDSPARSLKVQVTVVGVSSPFCSRVRALLLLAALGTLLLEVMVVHVLTAGSRAPKGTKQQTLMEPFAPGGDV", "length": 568, "header": "tr|A0A8V1AHG1-1|A0A8V1AHG1_CHICK Isoform 1 of Fc receptor like 4 OS=Gallus gallus OX=9031 GN=FCRL4 PE=4 SV=1 CANONICAL=A0A8V1AHG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1/entry#A0A8V1A9X3-1", "sequence": { "sequence": "MVLRAKPRRHRRFEDVAQALSLAVAEMALLTMDPPWSVIFQGESVTLRCQGPPVHKQQPTAWYHNGKLLEHTETNTYRIQNARYKQNGRYECQSPGSTSSNSVTLSVSYDLLILQVPSHAVFEGELLQMQCRGWKVGSLAAVRFYRDGADITKPYTSAMQLSIPQAKAHHSGRYHCSADMHSYLSLKRRESQGLYISIKELFTSPVLSVASSAEPLEGSPLNLSCITQLSPYRPHTVLWYLFYGNSTVLQGPVTSSEYQVPAVGLMDTGFYSCAVRTESSNVQKWSPRVPITIKRVPISGVSLEVWPQEGQVMEGHRLVLHCSVATGTGSISFSWHREGSAEVLGRDSRYEIPSTQQSDNGQYYCMASNGDSPARSLKVQVTVVGVSSPFCSRVRALLLLAALGTLLLEVMVVHVLTAGSRAPKGTKQQTLMEPFAPGGDV", "length": 441, "header": "tr|A0A8V1A9X3-1|A0A8V1A9X3_CHICK Computationally mapped isoform of Fc receptor like 4 OS=Gallus gallus OX=9031 GN=FCRL4 PE=4 SV=1 CANONICAL=A0A8V1AHG1-1" }, "locus": { "chromosome": "25", "start_pos": 2342735, "end_pos": 2335999, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069394.1", "url": "https://www.ensembl.org/id/ENSGALT00010069394.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042762.1", "url": "https://www.ensembl.org/id/ENSGALP00010042762.1" } ] } }, { "isoform_ac": "A0A8V1AHG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1/entry#A0A8V1AHG1-1", "sequence": { "sequence": "MEGWPLRSMGHLLLVLLWDMPGEGLDLLGEGDMFAYPVWLRGLGWSSGRPITIQAQGFLCRMVAGNAGQERNWGPARLAGMSTVRVGMLCHGVVGGARRCLGTWQTITKSHRPNDGSPPRAGSCRRPGSVGWSFSPHLFLLLAAQALSLAVAEMALLTMDPPWSVIFQGESVTLRCQGPPVHKQQPTAWYHNGKLLEHTETNTYRIQNARYKQNGRYECQSPGSTSSNSVTLSVSYDLLILQVPSHAVFEGELLQMQCRGWKVGSLAAVRFYRDGADITKPYTSAMQLSIPQAKAHHSGRYHCSADMHSYLSLKRRESQGLYISIKELFTSPVLSVASSAEPLEGSPLNLSCITQLSPYRPHTVLWYLFYGNSTVLQGPVTSSEYQVPAVGLMDTGFYSCAVRTESSNVQKWSPRVPITIKRVPISGVSLEVWPQEGQVMEGHRLVLHCSVATGTGSISFSWHREGSAEVLGRDSRYEIPSTQQSDNGQYYCMASNGDSPARSLKVQVTVVGVSSPFCSRVRALLLLAALGTLLLEVMVVHVLTAGSRAPKGTKQQTLMEPFAPGGDV", "length": 568, "header": "tr|A0A8V1AHG1-1|A0A8V1AHG1_CHICK Isoform 1 of Fc receptor like 4 OS=Gallus gallus OX=9031 GN=FCRL4 PE=4 SV=1 CANONICAL=A0A8V1AHG1-1" }, "locus": { "chromosome": "25", "start_pos": 2339440, "end_pos": 2335999, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069393.1", "url": "https://www.ensembl.org/id/ENSGALT00010069393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042761.1", "url": "https://www.ensembl.org/id/ENSGALP00010042761.1" } ] } }, { "isoform_ac": "A0A8V1AJN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1/entry#A0A8V1AJN2-1", "sequence": { "sequence": "MAVSRALLLLAQALSLAVAEMALLTMDPPWSVIFQGESVTLRCQGPPVHKQQPTAWYHNGKLLEHTETNTYRIQNARYKQNGRYECQSPGSTSSNSVTLSVSYDLLILQVPSHAVFEGELLQMQCRGWKVGSLAAVRFYRDGADITKPYTSAMQLSIPQAKAHHSGRYHCSADMHSYLSLKRRESQGLYISIKELFTSPVLSVASSAEPLEGSPLNLSCITQLSPYRPHTVLWYLFYGNSTVLQGPVTSSEYQVPAVGLMDTGFYSCAVRTESSNVQKWSPRVPITIKRVPISGVSLEVWPQEGQVMEGHRLVLHCSVATGTGSISFSWHREGSAEVLGRDSRYEIPSTQQSDNGQYYCMASNGDSPARSLKVQVTVVGVSSPFCSRVRALLLLAALGTLLLEVMVVHVLTAGSRAPKGTKQQTLMEPFAPGGDV", "length": 435, "header": "tr|A0A8V1AJN2-1|A0A8V1AJN2_CHICK Computationally mapped isoform of Fc receptor like 4 OS=Gallus gallus OX=9031 GN=FCRL4 PE=4 SV=1 CANONICAL=A0A8V1AHG1-1" }, "locus": { "chromosome": "25", "start_pos": 2339529, "end_pos": 2335999, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069391.1", "url": "https://www.ensembl.org/id/ENSGALT00010069391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042760.1", "url": "https://www.ensembl.org/id/ENSGALP00010042760.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425592", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425592", "resource": "KEGG Pathway" }, { "id": "R-GGA-1236978", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1236978", "resource": "Reactome", "description": "Cross-presentation of soluble exogenous antigens (endosomes)" }, { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" }, { "id": "R-GGA-2029481", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029481", "resource": "Reactome", "description": "FCGR activation" }, { "id": "R-GGA-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-GGA-2029485", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029485", "resource": "Reactome", "description": "Role of phospholipids in phagocytosis" }, { "id": "R-GGA-2454202", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2454202", "resource": "Reactome", "description": "Fc epsilon receptor (FCERI) signaling" }, { "id": "R-GGA-2730905", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2730905", "resource": "Reactome", "description": "Role of LAT2/NTAL/LAB on calcium mobilization" }, { "id": "R-GGA-2871796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871796", "resource": "Reactome", "description": "FCERI mediated MAPK activation" }, { "id": "R-GGA-2871809", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871809", "resource": "Reactome", "description": "FCERI mediated Ca+2 mobilization" }, { "id": "R-GGA-2871837", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871837", "resource": "Reactome", "description": "FCERI mediated NF-kB activation" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "Q96PJ5-1", "protein_name": "Fc receptor-like protein 4", "gene_name": "FCRL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES", "length": 515 }, "evidence": [ { "id": "A0A8V1AHG1", "url": "https://omabrowser.org/oma/group/A0A8V1AHG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 235, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 349, "end_pos": 351 }, { "start_pos": 372, "end_pos": 374 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHG3-1", "uniprot_ac": "A0A8V1AHG3", "uniprot_id": "A0A8V1AHG3_CHICK", "mass": { "chemical_mass": 93288.0, "monoisotopic_mass": 93288.0 }, "refseq": { "ac": "XP_024997151", "name": "golgin subfamily A member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997151" }, "gene_names": [ { "name": "GOLGA1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3" } ] }, { "name": "GOLGA1", "type": "synonym", "evidence": [ { "id": "XP_024997151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997151" } ] } ], "protein_names": [ { "name": "Golgin subfamily A member 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3/entry#names_and_taxonomy" } ] }, { "name": "Golgin-97", "type": "synonym", "evidence": [ { "id": "A0A8V1AHG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3/entry#names_and_taxonomy" } ] }, { "name": "golgin subfamily A member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024997151", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997151" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997151.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997151" } ] }, { "annotation": "Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. Mechanistically, captures transport vesicles arriving from endosomes via the protein TBC1D23. Recognized vesicles are then tethered to the trans-Golgi before subsequent SNARE engagement and vesicle fusion. Selectively regulates E-cadherin transport from the trans-Golgi network in tubulovesicular carriers.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AC85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC85#function" }, { "database": "UniProtKB", "id": "ARBA00093371", "url": "https://www.uniprot.org/uniprotkb/ARBA00093371#function" }, { "database": "UniProtKB", "id": "A0A8V1AHG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3", "locus": { "chromosome": "17", "start_pos": 10186682, "end_pos": 10171544, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028104", "url": "https://www.ensembl.org/id/ENSGALG00010028104" } ] } } ], "crossref": [ { "id": "A0A8V1AHG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "417097", "url": "https://www.ncbi.nlm.nih.gov/gene/417097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417097", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNCIIMD", "url": "https://omabrowser.org/oma/group/GNCIIMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC85", "url": "https://www.orthodb.org/?gene=A0A8V1AC85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHG3", "url": "https://www.orthodb.org/?gene=A0A8V1AHG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23157:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23157:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024997151", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997151", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFAKLKKKIAEEAAIAPRPGGAARIPRSISKESITSVGADSGDDFASDGSSSREDLSSQLFRRNEQIRKLEVKLSDYADQIRNLQKIKEKLENALEKHQDSSMRKFQEQNEAHQANRAKMAEGMALALEKKDQEWMEKLSHIEKEKKMLETQLQEMRERSLNLFQKRDEIDELEGFQQQEMAKVKHMLLKKEECLSKAEQELEARTRELIHAKEMLQEASTESSGLRKDLHELQEQFLEVEARRDELMTAERNAENKITALELREQELQTVIQHLSVDLQNARVAGSGCEKRLETLRVEHESLKVEYEQHKLKMTFEFAERSKLIEQLQEKVSSLEKKLERNLSGDEHVQELLKEKASLEQKLDETSQQILTDRMDHANGMNQLETQNRELEEKLQIATEALKMSKEAACEQDLKIQKLQMDVENERSKLQQQVLSEKHQYEQKISELESQIAALQTAWEFDKTAAQHKISQLEKENENLNGSREEYESSLKKQESVLNKLKKELSSRETVNTEIANTLEETEKQKDKLQQQVSHLASLIKDKDRLIDEKSGMLLKQKEELNQLRQDHEAALLQMHQLRSDIEASNSQAVEKEETARKEIEELKLQIQEFLLAREHEKNVSELEESARGLNEHLHLPENCATEQNGEVTATDVIQLQKDNRELEQQIVEKNKMIKQLQQRMAELKKTLQKELKIRPDSEVPELREKTNSEVPNASVTVTNNSDLNDSREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPSPKGSIRPSISSPRTLWS", "length": 804, "header": "tr|A0A8V1AHG3-1|A0A8V1AHG3_CHICK Isoform 1 of Golgin subfamily A member 1 OS=Gallus gallus OX=9031 GN=GOLGA1 PE=1 SV=1 CANONICAL=A0A8V1AHG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3/entry#A0A8V1AC85-1", "sequence": { "sequence": "MFAKLKKKIAEEAAIAPRPGGAARIPRSISKESITSVGADSGDDFASDGSSSREDLSSQLFRRNEQIRKLEVKLSASMRKFQEQNEAHQANRAKMAEGMALALEKKDQEWMEKLSHIEKEKKMLETQLQEMRERSLNLFQKRDEIDELEGFQQQEMAKVKHMLLKKEECLSKAEQELEARTRELIHAKEMLQEASTESSGLRKDLHELQEQFLEVEARRDELMTAERNAENKITALELREQELQTVIQHLSVDLQNARVAGSGCEKRLETLRVEHESLKVEYEQHKLKMTFEFAERSKLIEQLQEKVSSLEKKLERNLSGDEHVQELLKEKASLEQKLDETSQQILTDRMDHANGMNQLETQNRELEEKLQIATEALKMSKEAACEQDLKIQKLQMDVENERSKLQQQVLSEKHQYEQKISELESQIAALQTAWEFDKTAAQHKISQLEKENENLNGSREEYESSLKKQESVLNKLKKELSSRETVNTEIANTLEETEKQKDKLQQQVSHLASLIKDKDRLIDEKSGMLLKQKEELNQLRQDHEAALLQMHQLRSDIEASNSQAVEKEETARKEIEELKLQIQEFLLAREHEKNVSELEESARGLNEHLHLPENCATEQNGEVTATDVIQLQKDNRELEQQIVEKNKMIKQLQQRMAELKKTLQKELKIRPDSEVPELREKTNSEVPNASVTVTNNSDLNDSREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPSPKGSIRPSISSPRTLWS", "length": 779, "header": "tr|A0A8V1AC85-1|A0A8V1AC85_CHICK Computationally mapped isoform of Golgin subfamily A member 1 OS=Gallus gallus OX=9031 GN=GOLGA1 PE=1 SV=1 CANONICAL=A0A8V1AHG3-1" }, "locus": { "chromosome": "17", "start_pos": 10185775, "end_pos": 10172093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068093.1", "url": "https://www.ensembl.org/id/ENSGALT00010068093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041836.1", "url": "https://www.ensembl.org/id/ENSGALP00010041836.1" } ] } }, { "isoform_ac": "A0A8V1AHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3/entry#A0A8V1AHG3-1", "sequence": { "sequence": "MFAKLKKKIAEEAAIAPRPGGAARIPRSISKESITSVGADSGDDFASDGSSSREDLSSQLFRRNEQIRKLEVKLSDYADQIRNLQKIKEKLENALEKHQDSSMRKFQEQNEAHQANRAKMAEGMALALEKKDQEWMEKLSHIEKEKKMLETQLQEMRERSLNLFQKRDEIDELEGFQQQEMAKVKHMLLKKEECLSKAEQELEARTRELIHAKEMLQEASTESSGLRKDLHELQEQFLEVEARRDELMTAERNAENKITALELREQELQTVIQHLSVDLQNARVAGSGCEKRLETLRVEHESLKVEYEQHKLKMTFEFAERSKLIEQLQEKVSSLEKKLERNLSGDEHVQELLKEKASLEQKLDETSQQILTDRMDHANGMNQLETQNRELEEKLQIATEALKMSKEAACEQDLKIQKLQMDVENERSKLQQQVLSEKHQYEQKISELESQIAALQTAWEFDKTAAQHKISQLEKENENLNGSREEYESSLKKQESVLNKLKKELSSRETVNTEIANTLEETEKQKDKLQQQVSHLASLIKDKDRLIDEKSGMLLKQKEELNQLRQDHEAALLQMHQLRSDIEASNSQAVEKEETARKEIEELKLQIQEFLLAREHEKNVSELEESARGLNEHLHLPENCATEQNGEVTATDVIQLQKDNRELEQQIVEKNKMIKQLQQRMAELKKTLQKELKIRPDSEVPELREKTNSEVPNASVTVTNNSDLNDSREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPSPKGSIRPSISSPRTLWS", "length": 804, "header": "tr|A0A8V1AHG3-1|A0A8V1AHG3_CHICK Isoform 1 of Golgin subfamily A member 1 OS=Gallus gallus OX=9031 GN=GOLGA1 PE=1 SV=1 CANONICAL=A0A8V1AHG3-1" }, "locus": { "chromosome": "17", "start_pos": 10185775, "end_pos": 10172093, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068094.1", "url": "https://www.ensembl.org/id/ENSGALT00010068094.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041837.1", "url": "https://www.ensembl.org/id/ENSGALP00010041837.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417097", "resource": "KEGG Pathway" }, { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A6K4-1", "protein_name": "Golgin subfamily A member 1", "gene_name": "Golga1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKLKKKIAEETAVAQRPGCTPRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMEQLEKEKRFLTSQLQEVKNQSLSLFQKRDEIDELEGFQQQEISKVKHMLLKKEECLGKMEHELDARTRDLNRTQEELVTSNQLSSDLSQRLQELQRHCATLEEQRDHLTASKAGAEHKIVVLEQKEQELQAIIQQFSIDLQKVNAETQEKEKVITHLQDKVTFLEKRLEQDLSGEDHVQELLKEKTVAEQKLQDTRQQLLAAKNSHTKAVDLLETRVKDLEQSLQAAEEQLSQSRDVVAGQEAQIQKLITTNQENNLSQQQVLALEQHCRERIHALEAQIEALEQTRAADQIASEQGMRQLQQENVALKESRDECIQSLQHHQLELKKLKDEWNQREIVSVAMAQALEEVRKQREEFQQQATELTAIIEEKNQSLCEKDEALLQKEEELQQLEKGHNSALLQMHQLQRELETLKTFRAQEAMPATTGEDCLPLQGQEPLVISKAMQNCEYELPAAEGTPNGEVGAMDLKQLQKEKQDLEQQLTEKNKIMKQMQQRMLELKKTLQKELKIKPDNELFEVREKTGPEIPNMAPSVTNNTDLTEAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPAPKGSIRPSISNPRIPWS", "length": 758 }, "evidence": [ { "id": "A0A8V1AHG3", "url": "https://omabrowser.org/oma/group/A0A8V1AHG3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92805-1", "protein_name": "Golgin subfamily A member 1", "gene_name": "GOLGA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHLQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELEALRTLKAEEAAVVAEQEDLLRLRGPLQAEALSVNESHVTSRAMQDPVFQLPTAGRTPNGEVGAMDLTQLQKEKQDLEQQLLEKNKTIKQMQQRMLELRKTLQKELKIRPDNELFEVREKPGPEMANMAPSVTNNTDLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPAPKGSIRPSISNPRIPWS", "length": 767 }, "evidence": [ { "id": "A0A8V1AHG3", "url": "https://omabrowser.org/oma/group/A0A8V1AHG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CW79-1", "protein_name": "Golgin subfamily A member 1", "gene_name": "Golga1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAKLKKKIAEETAVAQRPGGTTRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQASRAKMAEGLALALARKDQEWSEKMEQLEKDKRFLTSQLQEVKNQSLSLFQKRDEIDELEGFQQQEISKVKHMLLKKEECLGKMEQELDARTRELNRTQEELVTSNQLSSDLNERLEELQRHCSTLEEQRDHLTASKAGAEHKIVVLEQKEQELQAIIQQHSIDLQKVTAETQEKEKVITHLQEKVIFLEKRLEQNLSGEDHVQELLKEKTVAEQNLEDTRQQLLAARNSHTKALYLLETRVKDLERSLQAAEEQLSQSRNVVADQEAQIQKLITTNQENSLSQQQVLALEQHCRERIHALEAQIEALEQTRVADQIASEQGMLQLQQENVALKESRNECEHSLQHHQLELKKLKDEWSQREIVSVAMAQALEEVRKQREEFQQQATELTAIIEEKNQSLCEKDEALLQKEQELRQLEKGHSSALLQMHKLQRELEALKTCKAQEAMPATTGEDCLPLQGQEPLVISKAMQNSEYELPAAEGTPNGEVGASDLKQLQKEKQDLEQQLIEKNKIMKQMQQRMLELKKTLQKELKIRPDSELFEVREKTGPEIPNMAPSVTNNTDLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPTPKGSIRPSISNPRIPWS", "length": 758 }, "evidence": [ { "id": "A0A8V1AHG3", "url": "https://omabrowser.org/oma/group/A0A8V1AHG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular 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}, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transepithelial transport", "id": "GO:0070633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular carrier activity", "id": "GO:0140104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG3" }, { "id": "PS50913", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50913" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRIP", "eco_id": "ECO_0000259", "start_pos": 725, "end_pos": 774, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 342, "end_pos": 344 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 619, "end_pos": 621 }, { "start_pos": 713, "end_pos": 715 }, { "start_pos": 720, "end_pos": 722 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 762, "end_pos": 764 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHG8-1", "uniprot_ac": "A0A8V1AHG8", "uniprot_id": "A0A8V1AHG8_CHICK", "mass": { "chemical_mass": 34713.0, "monoisotopic_mass": 34713.0 }, "refseq": {}, "gene_names": [ { "name": "CRPL2", "type": "recommended", "evidence": [ { "id": "A0A8V1AHG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8" } ] } ], "protein_names": [ { "name": "C-reactive protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AHG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8", "locus": { "chromosome": "25", "start_pos": 2431016, "end_pos": 2428938, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028683", "url": "https://www.ensembl.org/id/ENSGALG00010028683" } ] } } ], "crossref": [ { "id": "A0A8V1AHG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9Y1", "url": "https://www.orthodb.org/?gene=A0A8V1A9Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHG8", "url": "https://www.orthodb.org/?gene=A0A8V1AHG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45869:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45869:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTQRHVGQCPRSPGRKSGAAAKMSAQIQSSPIVPSMYRSLVLSCKVSGDPGPKEFVWEKKGIHKPLQKGPIDILLFRSLNKTHLGTYTCKVSSPQGTAVATYNLWIDDLKYRVFVFPQASNDSYVLLQARPEHPLLNFTVCLRSYTDLTRPHSLFSYATKEQDNEILLLKFKPTEYHFYVGGKYVAFHIPENYMDPEHVCVTWESPSGIVRFWLNGRPWPRKGLQKGYVVGNEAVVVLGQEQDAYGGGFDVLQSFTGEMSDVYMWDFGLSDSEVKMLHYSEPEVAPIFGWRNFPYKTEGEVYLMS", "length": 306, "header": "tr|A0A8V1AHG8-1|A0A8V1AHG8_CHICK Isoform 1 of C-reactive protein OS=Gallus gallus OX=9031 GN=CRPL2 PE=3 SV=1 CANONICAL=A0A8V1AHG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8/entry#A0A8V1A9Y1-1", "sequence": { "sequence": "MRAAGDNDKSAAAKMSAQIQSSPIVPSMYRSLVLSCKVSGDPGPKEFVWEKKGIHKPLQKGPIDILLFRSLNKTHLGTYTCKVSSPQGTAVATYNLWIDDLKYRVFVFPQASNDSYVLLQARPEHPLLNFTVCLRSYTDLTRPHSLFSYATKEQDNEILLLKFKPTEYHFYVGGKYVAFHIPENYMDPEHVCVTWESPSGIVRFWLNGRPWPRKGLQKGYVVGNEAVVVLGQEQDAYGGGFDVLQSFTGEMSDVYMWDFGLSDSEVKMLHYSEPEVAPIFGWRNFPYKTEGEVYLMS", "length": 297, "header": "tr|A0A8V1A9Y1-1|A0A8V1A9Y1_CHICK Computationally mapped isoform of C-reactive protein OS=Gallus gallus OX=9031 GN=CRPL2 PE=3 SV=1 CANONICAL=A0A8V1AHG8-1" }, "locus": { "chromosome": "25", "start_pos": 2430882, "end_pos": 2429137, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069437.1", "url": "https://www.ensembl.org/id/ENSGALT00010069437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042772.1", "url": "https://www.ensembl.org/id/ENSGALP00010042772.1" } ] } }, { "isoform_ac": "A0A8V1AHG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8/entry#A0A8V1AHG8-1", "sequence": { "sequence": "MSTQRHVGQCPRSPGRKSGAAAKMSAQIQSSPIVPSMYRSLVLSCKVSGDPGPKEFVWEKKGIHKPLQKGPIDILLFRSLNKTHLGTYTCKVSSPQGTAVATYNLWIDDLKYRVFVFPQASNDSYVLLQARPEHPLLNFTVCLRSYTDLTRPHSLFSYATKEQDNEILLLKFKPTEYHFYVGGKYVAFHIPENYMDPEHVCVTWESPSGIVRFWLNGRPWPRKGLQKGYVVGNEAVVVLGQEQDAYGGGFDVLQSFTGEMSDVYMWDFGLSDSEVKMLHYSEPEVAPIFGWRNFPYKTEGEVYLMS", "length": 306, "header": "tr|A0A8V1AHG8-1|A0A8V1AHG8_CHICK Isoform 1 of C-reactive protein OS=Gallus gallus OX=9031 GN=CRPL2 PE=3 SV=1 CANONICAL=A0A8V1AHG8-1" }, "locus": { "chromosome": "25", "start_pos": 2430882, "end_pos": 2429345, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069436.1", "url": "https://www.ensembl.org/id/ENSGALT00010069436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042771.1", "url": "https://www.ensembl.org/id/ENSGALP00010042771.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8" } ], "pmid": "" }, { "name": "acute-phase response", "id": "GO:0006953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHG8", "url": 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"table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHH3-1", "uniprot_ac": "A0A8V1AHH3", "uniprot_id": "A0A8V1AHH3_CHICK", "mass": { "chemical_mass": 34326.0, "monoisotopic_mass": 34326.0 }, "refseq": {}, "gene_names": [ { "name": "SUSD3", "type": "recommended", "evidence": [ { "id": "A0A8V1AHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3" } ] } ], "protein_names": [ { "name": "Sushi domain containing 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3", "locus": { "chromosome": "12", "start_pos": 6838157, "end_pos": 6867611, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027721", "url": "https://www.ensembl.org/id/ENSGALG00010027721" } ] } } ], "crossref": [ { "id": "A0A8V1AHH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415988", "url": "https://www.ncbi.nlm.nih.gov/gene/415988", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415988", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415988", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIWKGNG", "url": "https://omabrowser.org/oma/group/CIWKGNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5B3", "url": "https://www.orthodb.org/?gene=A0A8V1A5B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA71", "url": "https://www.orthodb.org/?gene=A0A8V1AA71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACZ1", "url": "https://www.orthodb.org/?gene=A0A8V1ACZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFK5", "url": "https://www.orthodb.org/?gene=A0A8V1AFK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHH3", "url": "https://www.orthodb.org/?gene=A0A8V1AHH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHH8", "url": "https://www.orthodb.org/?gene=A0A8V1AHH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46879", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46879", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46879:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46879:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFK5-1", "url": 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312, "header": "tr|A0A8V1AHH3-1|A0A8V1AHH3_CHICK Isoform 1 of Sushi domain containing 3 OS=Gallus gallus OX=9031 GN=SUSD3 PE=4 SV=1 CANONICAL=A0A8V1AHH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3/entry#A0A8V1A5B3-1", "sequence": { "sequence": "MPPLLLHVVYLPTQVWFQILLQKATTLRTKRRTYVITHTAPQGQCSHVHPPQLGTLQIIHGNGTAVGTVIAFQCAAEHQLEGPGIITCIWKGNDTQWTAEVPSCKPISKYETFGFKVAVIASIVSCAIILLMSMAFLTCCLIKCVKKSERRRTERDMQLWYQLRTEELENMHAAYFGYKGRNNNNNKKLRNKSVFDDMANVAYDNQGFYRFQEEWTRDTAAPGRCKAGEQLPKLSSSSSSSGTPGRHTGPGHSSAQHTVNSVHVVEVYGHTERYNKARCQIPG", "length": 283, "header": "tr|A0A8V1A5B3-1|A0A8V1A5B3_CHICK Computationally mapped isoform of Sushi domain containing 3 OS=Gallus gallus OX=9031 GN=SUSD3 PE=4 SV=1 CANONICAL=A0A8V1AHH3-1" }, "locus": { "chromosome": "12", "start_pos": 6862970, "end_pos": 6838601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067195.1", "url": "https://www.ensembl.org/id/ENSGALT00010067195.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041099.1", "url": "https://www.ensembl.org/id/ENSGALP00010041099.1" } ] } }, { "isoform_ac": "A0A8V1AA71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3/entry#A0A8V1AA71-1", "sequence": { "sequence": "MLTTKPYGQCSHVHPPQLGTLQIIHGNGTAVGTVIAFQCAAEHQLEGPGIITCIWKGNDTQWTAEVPSCKPISKYETFGFKVAVIASIVSCAIILLMSMAFLTCCLIKCVKKSERRRTERDMQLWYQLRTEELENMHAAYFGYKGRNNNNNKKLRNKSVFDDMANVAYDNQGFYRFQEEWTRDTAAPGRCKAGEQLPKLSSSSSSSGTPGRHTGPGHSSAQHTVNSVHVVEVYGHTERYNKARCQIPG", "length": 248, "header": "tr|A0A8V1AA71-1|A0A8V1AA71_CHICK Computationally mapped isoform of Sushi domain containing 3 OS=Gallus gallus OX=9031 GN=SUSD3 PE=4 SV=1 CANONICAL=A0A8V1AHH3-1" }, "locus": { "chromosome": "12", "start_pos": 6853660, "end_pos": 6838601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067192.1", "url": "https://www.ensembl.org/id/ENSGALT00010067192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041096.1", "url": "https://www.ensembl.org/id/ENSGALP00010041096.1" } ] } }, { "isoform_ac": "A0A8V1ACZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3/entry#A0A8V1ACZ1-1", "sequence": { "sequence": "MPAATAPGPDEPRTAAPGRDGGGPRGYTGQCSHVHPPQLGTLQIIHGNGTAVGTVIAFQCAAEHQLEGPGIITCIWKGNDTQWTAEVPSCKPISKYETFGFKVAVIASIVSCAIILLMSMAFLTCCLIKCVKKSERRRTERDMQLWYQLRTEELENMHAAYFGYKGRNNNNNKKLRNKSVFDDMANVAYDNQGFYRFQEEWTRDTAAPGRCKAGEQLPKLSSSSSSSGTPGRHTGPGHSSAQHTVNSVHVVEVYGHTERYNKARCQIPG", "length": 269, "header": "tr|A0A8V1ACZ1-1|A0A8V1ACZ1_CHICK Computationally mapped isoform of Sushi domain containing 3 OS=Gallus gallus OX=9031 GN=SUSD3 PE=4 SV=1 CANONICAL=A0A8V1AHH3-1" }, "locus": { "chromosome": "12", "start_pos": 6862500, "end_pos": 6838601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067194.1", "url": "https://www.ensembl.org/id/ENSGALT00010067194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041098.1", "url": "https://www.ensembl.org/id/ENSGALP00010041098.1" } ] } }, { "isoform_ac": "A0A8V1AFK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3/entry#A0A8V1AFK5-1", "sequence": { "sequence": "MCLHEGQCSHVHPPQLGTLQIIHGNGTAVGTVIAFQCAAEHQLEGPGIITCIWKGNDTQWTAEVPSCKPISKYETFGFKVAVIASIVSCAIILLMSMAFLTCCLIKCVKKSERRRTERDMQLWYQLRTEELENMHAAYFGYKGRNNNNNKKLRNKSVFDDMANVAYDNQGFYRFQEEWTRDTAAPGRCKAGEQLPKLSSSSSSSGTPGRHTGPGHSSAQHTVNSVHVVEVYGHTERYNKARCQIPG", "length": 246, "header": "tr|A0A8V1AFK5-1|A0A8V1AFK5_CHICK Computationally mapped isoform of Sushi domain containing 3 OS=Gallus gallus OX=9031 GN=SUSD3 PE=4 SV=1 CANONICAL=A0A8V1AHH3-1" }, "locus": { "chromosome": "12", "start_pos": 6860708, "end_pos": 6838601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067193.1", "url": "https://www.ensembl.org/id/ENSGALT00010067193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041097.1", "url": "https://www.ensembl.org/id/ENSGALP00010041097.1" } ] } }, { "isoform_ac": "A0A8V1AHH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3/entry#A0A8V1AHH3-1", "sequence": { "sequence": "MGLRAEELLAGITGSGHGLAPGRASSIAHAELCSLLWPLTWADLKYDYDQPTKVNLHFLLSCCIASCICSAGQCSHVHPPQLGTLQIIHGNGTAVGTVIAFQCAAEHQLEGPGIITCIWKGNDTQWTAEVPSCKPISKYETFGFKVAVIASIVSCAIILLMSMAFLTCCLIKCVKKSERRRTERDMQLWYQLRTEELENMHAAYFGYKGRNNNNNKKLRNKSVFDDMANVAYDNQGFYRFQEEWTRDTAAPGRCKAGEQLPKLSSSSSSSGTPGRHTGPGHSSAQHTVNSVHVVEVYGHTERYNKARCQIPG", "length": 312, "header": "tr|A0A8V1AHH3-1|A0A8V1AHH3_CHICK Isoform 1 of Sushi domain containing 3 OS=Gallus gallus OX=9031 GN=SUSD3 PE=4 SV=1 CANONICAL=A0A8V1AHH3-1" }, "locus": { "chromosome": "12", "start_pos": 6849814, "end_pos": 6838601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067191.1", "url": "https://www.ensembl.org/id/ENSGALT00010067191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041095.1", "url": "https://www.ensembl.org/id/ENSGALP00010041095.1" } ] } }, { "isoform_ac": "A0A8V1AHH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3/entry#A0A8V1AHH8-1", "sequence": { "sequence": "MQTRQCSHVHPPQLGTLQIIHGNGTAVGTVIAFQCAAEHQLEGPGIITCIWKGNDTQWTAEVPSCKPISKYETFGFKVAVIASIVSCAIILLMSMAFLTCCLIKCVKKSERRRTERDMQLWYQLRTEELENMHAAYFGYKGRNNNNNKKLRNKSVFDDMANVAYDNQGFYRFQEEWTRDTAAPGRCKAGEQLPKLSSSSSSSGTPGRHTGPGHSSAQHTVNSVHVVEVYGHTERYNKARCQIPG", "length": 244, "header": "tr|A0A8V1AHH8-1|A0A8V1AHH8_CHICK Computationally mapped isoform of Sushi domain containing 3 OS=Gallus gallus OX=9031 GN=SUSD3 PE=4 SV=1 CANONICAL=A0A8V1AHH3-1" }, "locus": { "chromosome": "12", "start_pos": 6867553, "end_pos": 6838601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067196.1", "url": "https://www.ensembl.org/id/ENSGALT00010067196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041100.1", "url": "https://www.ensembl.org/id/ENSGALP00010041100.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 272, "start_aa": "Thr", "end_pos": 272, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr272", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415988", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415988", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH3" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 135, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 272 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHH6-1", "uniprot_ac": "A0A8V1AHH6", "uniprot_id": "A0A8V1AHH6_CHICK", "mass": { "chemical_mass": 341372.0, "monoisotopic_mass": 341372.0 }, "refseq": {}, "gene_names": [ { "name": "BPTF", "type": "recommended", "evidence": [ { "id": "A0A8V1AHH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6" } ] } ], "protein_names": [ { "name": "Bromodomain PHD finger transcription factor", "type": "synonym", "evidence": [ { "id": "A0A8V1AHH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BPTF", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6", "locus": { "chromosome": "18", "start_pos": 7629998, "end_pos": 7676823, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029322", "url": "https://www.ensembl.org/id/ENSGALG00010029322" } ] } } ], "crossref": [ { "id": "cd05509", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05509", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15559", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15559", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15560", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15560", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC76", "url": "https://www.orthodb.org/?gene=A0A8V1AC76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC81", "url": "https://www.orthodb.org/?gene=A0A8V1AC81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHH6", "url": "https://www.orthodb.org/?gene=A0A8V1AHH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJJ3", "url": "https://www.orthodb.org/?gene=A0A8V1AJJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALL6", "url": "https://www.orthodb.org/?gene=A0A8V1ALL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN57", "url": "https://www.orthodb.org/?gene=A0A8V1AN57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45975", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45975", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45975:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45975:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AC76", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC81", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN57", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSDEEEEADPEDNQDSEEEEEEEIMEEEDDDDSDYPEEMEDEDDASYCTESSFRSHSTYSSTPGRRRQRVHRPRSPILEEKDIPPLEFPKSSEDLMVPSEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHIVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQETEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRHRRKYWFLNRRIIIEEDSESEKDKKVWYYSTKIQLAELIECLDKDYWEADLCKTLEEMREEVHRHMDVTEDLTNKARGTNKSFLSAANDEILDVIRARRGEIGEDRNTPADEAEKAKSDAENDQTDVEKSKEESGDQEKTEDTPTEQSVEKVKNEEATVIGDKSNCLTSSTDDNNTNPSAGETSCSEGKNAMGCQSETPDSNNVAEKKVASELHQELSEETGQMIPTNSSASAAAPQADVENSSSSELSSGQNDSIKMPDDAENAEGGLQTSEDIGEKANGERSDSPGAGKGTPGSTRMLTRLRNPDSKLCQMKSQQVAAAAHEANKLNKENREVLVVNSQGEVSRMNTKREIVMKGNINNYFKLGQEGKYRVYHNQYATNSFALNKHQHREDHDKRRHLSHKFCLTTAGEFKWNGSVHGSKVLTISTLRLTIIQLENNIPASFLHPNWASHRSNWIKAVQMCSKPREFALALAILECAIKPVVMLPIWRESLGHTRLRRMTAIEREEKEKVKKKERKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVHRFMPKLPGNTNANYRKLLPTKNEDEKCNLDKRKGPIKVKIEKDRMKDSHDLQAKHKGDTSEAAEKVQVKEEKSHEEKVDTNSENLGHAKDKVEKEIDGENYKVIKEEPMDIDTKTESSIKDEDSHCKLDIINVSEGFHLRTCYKRKVKSSKLDGLLERRIKQFTLEEKQRLERMKLEASAKNGGIQSLSSQKNLDELQMKKVKEGSQSVTSSQNQTYVSDKIQREDTGQDCLPVSSISCMKTGEQDELSLPSTNRLSKREGQLLDEDSPQPSEGERSIQNDSKDNNSEPVAADKSQVQEDVTEHESSFVDDLKQTNTDGKVKWDVLETNEKPLKQKLPITRVSQKEYENSEPLITKSSCRKGALAIPDKTNTEGNSQQQSRDPEKNCMIKSNFEPLSFQESKLEKDIIPKKTESKSENKIAFHQKLVSKDIESLKTELISERDLGSQTLEHEDGAKVDEELLRSQLTEANGQKKGQELKVETNTINKYLDQTNLNSVTDKKNNKDEETEMDLEKDKSTFQMNGKDNDIKVLSNDESLVKVTYGATADDIEPRVNNINKSFPEHEMKPLTSKESSVKPFMNGDITTEDSADKNAVDPKSSLQSSPEFEAEKTLQPSEEAPKYVQKTEEKHLSPQRSSFLDTSSTPTHDFCKENNLSSETESMETEDTEDKKVTSSPVMSCEESSLSSDFADQNGLQTYKVEDVNGESKIKTVITEVTTTTSTVSTESKTVFKVAETLASNDEKTVVSSTENCAISTVTTTTTVTKLTTPATDSNVDVISVQEHRKTVVTTTVTDSLSTPEGTLVTSMTVSKEYSTKDKVKLMKFTKPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARRGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWACLKWDDMAAKAPPGGGTTRTETTETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKQIPVAGVAATVTTASSTTSTVSTPQKVVVGPLAGPVPTGTKVVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSSTATSTAATSATTIASTGQTFQISGSPVTMAGKVITKLPLPANSKIVAVNVPSTQGGVVQVQQKVLGIIPSTTGASQTFTSFQPRTATVTIRPNTTGTLGTTSTSQVMQGTPLRPGMTVIRTPLQQSTLGKTIIRTPLVVQQGILPASQSQQVVTQIIRGQPVSTAVSSTSTASTSSGQKTVTSPGTPPQQIQPQTASQPPRPQQGQVKLTMAQLTQLTQGQGGSQGLTVVIQGQGQTTGQLQLIPQGVTVIPGPGQQLMQAAMPNGTIQRFLFTPLPAAATTASTTTTTASTSTSATEQKQALQAQPASVLPPVQPQPQSQQQSQPQAQNQSAQPVSPTQPQAPQPPLQPETQTQLESQTPASLDSPVTPETQSSKSPVQSPAQTQAQGQSPTQVQSQPQSAVLPQGQSQVQPQQPAQVQTTTQQQIQMQPHAPIQIQPQLQQLQPQVQTSVSTLPTTQSLNQVPVQSPTRPQLQLQQPPTKVITVPQLQQQVQVLSQLQSHVVAQIQAQQGSVPQQIKLQLPIQIQQSSPVQAHQIQNVVTVQAASVQEQLQRVQQLREQQQKKKQQQIEIKREHTLQASNQSDIIQKQVVMKQNAVIEHLKQKKTLTPTEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLKAEILKKRALLDKELQIEVQEELKRDLTKIKKEKEKAQAAAAAAAAAAAAAAAAASATPPPPPPPLPSPPQHHTASVTSSSSTTVPVPISSQKRKRDEERDLSASKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLSPLTDKDYEGLRRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERILKRYYKKVTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 3056, "header": "tr|A0A8V1AHH6-1|A0A8V1AHH6_CHICK Isoform 1 of Bromodomain PHD finger transcription factor OS=Gallus gallus OX=9031 GN=BPTF PE=1 SV=1 CANONICAL=A0A8V1AHH6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6/entry#A0A8V1AC76-1", "sequence": { "sequence": "MRGRRGRPPKQQQPAAGTAQASSPAPPSAAGPIGGLRSRQRGSSRGRWASSAQAETAAGPKQKGAGAAQASSSAAVSPRGGSKRKGGSGSSSTPGGGGSSGKGRGRAGAGGAGGGGGGGSCNSQGRAASSRRSISKVVYDDHESEEEEESMVSDEEEEADPEDNQDSEEEEEEEIMEEEDDDDSDYPEEMEDEDDASYCTESSFRSHSTYSSTPGRRRQRVHRPRSPILEEKDIPPLEFPKSSEDLMVPSEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHIVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQETEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRHRRKYWFLNRRIIIEEDSESEKDKKVWYYSTKIQLAELIECLDKDYWEADLCKTLEEMREEVHRHMDVTEDLTNKARGTNKSFLSAANDEILDVIRARRGEIGEDRNTPADEAEKAKSDAENDQTDVEKSKEESGDQEKTEDTPTEQSVEKVKNEEETGQMIPTNSSASAAAPQADVENSSSSELSSGQNDSIKMPDDAENAEGGLQTSEDIGEKANGERSDSPGAGKGTPGSTRMLTRLRNPDSKLCQMKSQQVAAAAHEANKLNKENREVLVVNSQGEVSRMNTKREIVMKGNINNYFKLGQEGKYRVYHNQYATNSFALNKHQHREDHDKRRHLSHKFCLTTAGEFKWNGSVHGSKVLTISTLRLTIIQLENNIPASFLHPNWASHRSNWIKAVQMCSKPREFALALAILECAIKPVVMLPIWRESLGHTRLRRMTAIEREEKEKVKKKERKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVHRFMPKLPGNTNANYRKLLPTKNEDEKCNLDKRKGPIKVKIEKDRMKDSHDLQAKHKGDTSEAAEKVQVKEEKSHEEKVDTNSENLGHAKDKVEKEIDGENYKVIKEEPMDIDTKTESSIKDEDSHCKLDIINVSEGFHLRTCYKRKVKSSKLDGLLERRIKQFTLEEKQRLERMKLEASAKNGGIQSLSSQKNLDELQMKKVKEGSQSVTSSQNQTYVSDKIQREDTGQDCLPVSSISCMKTGEQDELSLPSTNRLSKREGQLLDEDSPQPSEGERSIQNDSKDNNSEPVAADKSQVQEDVTEHESSFVDDLKQTNTDGKVKWDVLETNEKPLKQKLPITRVSQKEYENSEPLITKSSCRKGALAIPDKTNTEGNSQQQSRDPEKNCMIKSNFEPLSFQESKLEKDIIPKKTESKSENKIAFHQKLVSKDIESLKTELISERDLGSQTLEHEDGAKVDEELLRSQLTEANGQKKGQELKVETNTINKYLDQTNLNSVTDKKNNKDEETEMDLEKDKSTFQMNGKDNDIKVLSNDESLVKVTYGATADDIEPRVNNINKSFPEHEMKPLTSKESSVKPFMNGDITTEDSADKNAVDPKSSLQSSPEFEAEKTLQPSEEAPKYVQKTEEKHLSPQRSSFLDTSSTPTHDFCKENNLSSETESMETEDTEDKKVTSSPVMSCEESSLSSDFADQNGLQTYKVEDVNGESKIKTVITEVTTTTSTVSTESKTVFKVAETLASNDEKTVVSSTENCAISTVTTTTTVTKLTTPATDSNVDVISVQEHRKTVVTTTVTDSLSTPEGTLVTSMTVSKEYSTKDKVKLMKFTKPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARRGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWACLKWDDMAAKAPPGGGTTRTETTETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKQIPVAGVAATVTTASSTTSTVSTPQKVVVGPLAGPVPTGTKVVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSSTGVVQVQQKVLGIIPSTTGASQTFTSFQPRTATVTIRPNTTGTLGTTSTSQVMQGTPLRPGMTVIRTPLQQSTLGKTIIRTPLVVQQGILPASQSQQVVTQIIRGQPVSTAVSSTSTASTSSGQKTVTSPGTPPQQIQPQTASQPPRPQQGQVKLTMAQLTQLTQGQGGSQGLTVVIQGQGQTTGQLQLIPQGVTVIPGPGQQLMQAAMPNGTIQRFLFTPLPAAATTASTTTTTASTSTSATEQKQALQAQPASVLPPVQPQPQSQQQSQPQAQNQSAQPVSPTQPQAPQPPLQPETQTQLESQTPASLDSPVTPETQSSKSPVQSPAQTQAQGQSPTQVQSQPQSAVLPQGQSQVQPQQPAQVVMKQNAVIEHLKQKKTLTPTEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLKAEILKKRALLDKELQIEVQEELKRDLTKIKKEKEKAQAAAAAAAAAAAAAAAAASATPPPPPPPLPSPPQHHTASVTSSSSTTVPVPISSQKRKRDEERDLSASKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLSPLTDKDYEGLRRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERILKRYYKKVTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRKTDEEYFPNVDISENE", "length": 2864, "header": "tr|A0A8V1AC76-1|A0A8V1AC76_CHICK Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Gallus gallus OX=9031 GN=BPTF PE=1 SV=1 CANONICAL=A0A8V1AHH6-1" }, "locus": { "chromosome": "18", "start_pos": 7676624, "end_pos": 7632290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070911.1", "url": "https://www.ensembl.org/id/ENSGALT00010070911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043602.1", "url": "https://www.ensembl.org/id/ENSGALP00010043602.1" } ] } }, { "isoform_ac": "A0A8V1AC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6/entry#A0A8V1AC81-1", "sequence": { "sequence": "MVSDEEEEADPEDNQDSEEEEEEEIMEEEDDDDSDYPEEMEDEDDASYCTESSFRSHSTYSSTPGRRRQRVHRPRSPILEEKDIPPLEFPKSSEDLMVPSEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHIVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQETEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRHRRKYWFLNRRIIIEEDSESEKDKKVWYYSTKIQLAELIECLDKDYWEADLCKTLEEMREEVHRHMDVTEDLTNKARGTNKSFLSAANDEILDVIRARRGEIGEDRNTPADEAEKAKSDAENDQTDVEKSKEESGDQEKTEDTPTEQSVEKVKNEEETGQMIPTNSSASAAAPQADVENSSSSELSSGQNDSIKMPDDAENAEGGLQTSEDIGEKANGERSDSPGAGKGTPGSTRMLTRLRNPDSKLCQMKSQQVAAAAHEANKLNKENREVLVVNSQGEVSRMNTKREIVMKGNINNYFKLGQEGKYRVYHNQYATNSFALNKHQHREDHDKRRHLSHKFCLTTAGEFKWNGSVHGSKVLTISTLRLTIIQLENNIPASFLHPNWASHRSNWIKAVQMCSKPREFALALAILECAIKPVVMLPIWRESLGHTRLRRMTAIEREEKEKVKKKERKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVHRFMPKLPGNTNANYRKLLPTKNEDEKCNLDKRKGPIKVKIEKDRMKDSHDLQAKHKGDTSEAAEKVQVKEEKSHEEKVDTNSENLGHAKDKVEKEIDGENYKVIKEEPMDIDTKTESSIKDEDSHCKLDIINVSEGFHLRTCYKRKVKSSKLDGLLERRIKQFTLEEKQRLERMKLEASAKNGGIQSLSSQKNLDELQMKKVKEGSQSVTSSQNQTYVSDKIQREDTGQDCLPVSSISCMKTGEQDELSLPSTNRLSKREGQLLDEDSPQPSEGERSIQNDSKDNNSEPVAADKSQVQEDVTEHESSFVDDLKQTNTDGKVKWDVLETNEKPLKQKLPITRVSQKEYENSEPLITKSSCRKGALAIPDKTNTEGNSQQQSRDPEKNCMIKSNFEPLSFQESKLEKDIIPKKTESKSENKIAFHQKLVSKDIESLKTELISERDLGSQTLEHEDGAKVDEELLRSQLTEANGQKKGQELKVETNTINKYLDQTNLNSVTDKKNNKDEETEMDLEKDKSTFQMNGKDNDIKVLSNDESLVKVTYGATADDIEPRVNNINKSFPEHEMKPLTSKESSVKPFMNGDITTEDSADKNAVDPKSSLQSSPEFEAEKTLQPSEEAPKYVQKTEEKHLSPQRSSFLDTSSTPTHDFCKENNLSSETESMETEDTEDKKVTSSPVMSCEESSLSSDFADQNGLQTYKVEDVNGESKIKTVITEVTTTTSTVSTESKTVFKVAETLASNDEKTVVSSTENCAISTVTTTTTVTKLTTPATDSNVDVISVQEHRKTVVTTTVTDSLSTPEGTLVTSMTVSKEYSTKDKVKLMKFTKPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARRGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWACLKWDDMAAKAPPGGGTTRTETTETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKQIPVAGVAATVTTASSTTSTVSTPQKVVVGPLAGPVPTGTKVVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSSTGVVQVQQKVLGIIPSTTGASQTFTSFQPRTATVTIRPNTTGTLGTTSTSQVMQGTPLRPGMTVIRTPLQQSTLGKTIIRTPLVVQQGILPASQSQQVVTQIIRGQPVSTAVSSTSTASTSSGQKTVTSPGTPPQQIQPQTASQPPRPQQGQVKLTMAQLTQLTQGQGGSQGLTVVIQGQGQTTGQLQLIPQGVTVIPGPGQQLMQAAMPNGTIQRFLFTPLPAAATTASTTTTTASTSTSATEQKQALQAQPASVLPPVQPQPQSQQQSQPQAQNQSAQPVSPTQPQAPQPPLQPETQTQLESQTPASLDSPVTPETQSSKSPVQSPAQTQAQGQSPTQVQSQPQSAVLPQGQSQVQPQQPAQVQTTTQQQIQMQPHAPIQIQPQLQQLQPQVQTSVSTLPTTQSLNQVPVQSPTRPQLQLQQPPTKVITVPQLQQQVQVLSQLQSHVVAQIQAQQGSVPQQIKLQLPIQIQQSSPVQAHQIQNVVTVQAASVQEQLQRVQQLREQQQKKKQQQIEIKREHTLQASNQSDIIQKQVVMKQNAVIEHLKQKKTLTPTEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLKAEILKKRALLDKELQIEVQEELKRDLTKIKKEKEKAQAAAAAAAAAAAAAAAAASATPPPPPPPLPSPPQHHTASVTSSSSTTVPVPISSQKRKRDEERDLSASKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLSPLTDKDYEGLRRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERILKRYYKKVTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 2939, "header": "tr|A0A8V1AC81-1|A0A8V1AC81_CHICK Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Gallus gallus OX=9031 GN=BPTF PE=1 SV=1 CANONICAL=A0A8V1AHH6-1" }, "locus": { "chromosome": "18", "start_pos": 7676174, "end_pos": 7631002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070916.1", "url": "https://www.ensembl.org/id/ENSGALT00010070916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043607.1", "url": "https://www.ensembl.org/id/ENSGALP00010043607.1" } ] } }, { "isoform_ac": "A0A8V1AHH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6/entry#A0A8V1AHH6-1", "sequence": { "sequence": "MVSDEEEEADPEDNQDSEEEEEEEIMEEEDDDDSDYPEEMEDEDDASYCTESSFRSHSTYSSTPGRRRQRVHRPRSPILEEKDIPPLEFPKSSEDLMVPSEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHIVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQETEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRHRRKYWFLNRRIIIEEDSESEKDKKVWYYSTKIQLAELIECLDKDYWEADLCKTLEEMREEVHRHMDVTEDLTNKARGTNKSFLSAANDEILDVIRARRGEIGEDRNTPADEAEKAKSDAENDQTDVEKSKEESGDQEKTEDTPTEQSVEKVKNEEATVIGDKSNCLTSSTDDNNTNPSAGETSCSEGKNAMGCQSETPDSNNVAEKKVASELHQELSEETGQMIPTNSSASAAAPQADVENSSSSELSSGQNDSIKMPDDAENAEGGLQTSEDIGEKANGERSDSPGAGKGTPGSTRMLTRLRNPDSKLCQMKSQQVAAAAHEANKLNKENREVLVVNSQGEVSRMNTKREIVMKGNINNYFKLGQEGKYRVYHNQYATNSFALNKHQHREDHDKRRHLSHKFCLTTAGEFKWNGSVHGSKVLTISTLRLTIIQLENNIPASFLHPNWASHRSNWIKAVQMCSKPREFALALAILECAIKPVVMLPIWRESLGHTRLRRMTAIEREEKEKVKKKERKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVHRFMPKLPGNTNANYRKLLPTKNEDEKCNLDKRKGPIKVKIEKDRMKDSHDLQAKHKGDTSEAAEKVQVKEEKSHEEKVDTNSENLGHAKDKVEKEIDGENYKVIKEEPMDIDTKTESSIKDEDSHCKLDIINVSEGFHLRTCYKRKVKSSKLDGLLERRIKQFTLEEKQRLERMKLEASAKNGGIQSLSSQKNLDELQMKKVKEGSQSVTSSQNQTYVSDKIQREDTGQDCLPVSSISCMKTGEQDELSLPSTNRLSKREGQLLDEDSPQPSEGERSIQNDSKDNNSEPVAADKSQVQEDVTEHESSFVDDLKQTNTDGKVKWDVLETNEKPLKQKLPITRVSQKEYENSEPLITKSSCRKGALAIPDKTNTEGNSQQQSRDPEKNCMIKSNFEPLSFQESKLEKDIIPKKTESKSENKIAFHQKLVSKDIESLKTELISERDLGSQTLEHEDGAKVDEELLRSQLTEANGQKKGQELKVETNTINKYLDQTNLNSVTDKKNNKDEETEMDLEKDKSTFQMNGKDNDIKVLSNDESLVKVTYGATADDIEPRVNNINKSFPEHEMKPLTSKESSVKPFMNGDITTEDSADKNAVDPKSSLQSSPEFEAEKTLQPSEEAPKYVQKTEEKHLSPQRSSFLDTSSTPTHDFCKENNLSSETESMETEDTEDKKVTSSPVMSCEESSLSSDFADQNGLQTYKVEDVNGESKIKTVITEVTTTTSTVSTESKTVFKVAETLASNDEKTVVSSTENCAISTVTTTTTVTKLTTPATDSNVDVISVQEHRKTVVTTTVTDSLSTPEGTLVTSMTVSKEYSTKDKVKLMKFTKPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARRGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWACLKWDDMAAKAPPGGGTTRTETTETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKQIPVAGVAATVTTASSTTSTVSTPQKVVVGPLAGPVPTGTKVVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSSTATSTAATSATTIASTGQTFQISGSPVTMAGKVITKLPLPANSKIVAVNVPSTQGGVVQVQQKVLGIIPSTTGASQTFTSFQPRTATVTIRPNTTGTLGTTSTSQVMQGTPLRPGMTVIRTPLQQSTLGKTIIRTPLVVQQGILPASQSQQVVTQIIRGQPVSTAVSSTSTASTSSGQKTVTSPGTPPQQIQPQTASQPPRPQQGQVKLTMAQLTQLTQGQGGSQGLTVVIQGQGQTTGQLQLIPQGVTVIPGPGQQLMQAAMPNGTIQRFLFTPLPAAATTASTTTTTASTSTSATEQKQALQAQPASVLPPVQPQPQSQQQSQPQAQNQSAQPVSPTQPQAPQPPLQPETQTQLESQTPASLDSPVTPETQSSKSPVQSPAQTQAQGQSPTQVQSQPQSAVLPQGQSQVQPQQPAQVQTTTQQQIQMQPHAPIQIQPQLQQLQPQVQTSVSTLPTTQSLNQVPVQSPTRPQLQLQQPPTKVITVPQLQQQVQVLSQLQSHVVAQIQAQQGSVPQQIKLQLPIQIQQSSPVQAHQIQNVVTVQAASVQEQLQRVQQLREQQQKKKQQQIEIKREHTLQASNQSDIIQKQVVMKQNAVIEHLKQKKTLTPTEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLKAEILKKRALLDKELQIEVQEELKRDLTKIKKEKEKAQAAAAAAAAAAAAAAAAASATPPPPPPPLPSPPQHHTASVTSSSSTTVPVPISSQKRKRDEERDLSASKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLSPLTDKDYEGLRRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERILKRYYKKVTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 3056, "header": "tr|A0A8V1AHH6-1|A0A8V1AHH6_CHICK Isoform 1 of Bromodomain PHD finger transcription factor OS=Gallus gallus OX=9031 GN=BPTF PE=1 SV=1 CANONICAL=A0A8V1AHH6-1" }, "locus": { "chromosome": "18", "start_pos": 7676174, "end_pos": 7631002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070913.1", "url": "https://www.ensembl.org/id/ENSGALT00010070913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043604.1", "url": "https://www.ensembl.org/id/ENSGALP00010043604.1" } ] } }, { "isoform_ac": "A0A8V1AJJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6/entry#A0A8V1AJJ3-1", "sequence": { "sequence": "MVSDEEEEADPEDNQDSEEEEEEEIMEEEDDDDSDYPEEMEDEDDASYCTESSFRSHSTYSSTPGRRRQRVHRPRSPILEEKDIPPLEFPKSSEDLMVPSEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHIVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQETEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRHRRKYWFLNRRIIIEEDSESEKDKKVWYYSTKIQLAELIECLDKDYWEADLCKTLEEMREEVHRHMDVTEDLTNKARGTNKSFLSAANDEILDVIRARRGEIGEDRNTPADEAEKAKSDAENDQTDVEKSKEESGDQEKTEDTPTEQSVEKVKNEEATVIGDKSNCLTSSTDDNNTNPSAGETSCSEGKNAMGCQSETPDSNNVAEKKVASELHQELSEETGQMIPTNSSASAAAPQADVENSSSSELSSGQNDSIKMPDDAENAEGGLQTSEDIGEKANGERSDSPGAGKGTPGSTRMLTRLRNPDSKLCQMKSQQVAAAAHEANKLNKENREVLVVNSQGEVSRMNTKREIVMKGNINNYFKLGQEGKYRVYHNQYATNSFALNKHQHREDHDKRRHLSHKFCLTTAGEFKWNGSVHGSKVLTISTLRLTIIQLENNIPASFLHPNWASHRSNWIKAVQMCSKPREFALALAILECAIKPVVMLPIWRESLGHTRLRRMTAIEREEKEKVKKKERKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVHRFMPKLPGNTNANYRKLLPTKNEDEKCNLDKRKGPIKVKIEKDRMKDSHDLQAKHKGDTSEAAEKVQVKEEKSHEEKVDTNSENLGHAKDKVEKEIDGENYKVIKEEPMDIDTKTESSIKDEDSHCKLDIINVSEGFHLRTCYKRKVKSSKLDGLLERRIKQFTLEEKQRLERMKLEASAKNGGIQSLSSQKNLDELQMKKVKEGSQSVTSSQNQTYVSDKIQREDTGQDCLPVSSISCMKTGEQDELSLPSTNRLSKREGQLLDEDSPQPSEGERSIQNDSKDNNSEPVAADKSQVQEDVTEHESSFVDDLKQTNTDGKVKWDVLETNEKPLKQKLPITRVSQKEYENSEPLITKSSCRKGALAIPDKTNTEGNSQQQSRDPEKNCMIKSNFEPLSFQESKLEKDIIPKKTESKSENKIAFHQKLVSKDIESLKTELISERDLGSQTLEHEDGAKVDEELLRSQLTEANGQKKGQELKVETNTINKYLDQTNLNSVTDKKNNKDEETEMDLEKDKSTFQMNGKDNDIKVLSNDESLVKVTYGATADDIEPRVNNINKSFPEHEMKPLTSKESSVKPFMNGDITTEDSADKNAVDPKSSLQSSPEFEAEKTLQPSEEAPKYVQKTEEKHLSPQRSSFLDTSSTPTHDFCKENNLSSETESMETEDTEDKKVTSSPVMSCEESSLSSDFADQNGLQTYKVEDVNGESKIKTVITEVTTTTSTVSTESKTVFKVAETLASNDEKTVVSSTENCAISTVTTTTTVTKLTTPATDSNVDVISVQEHRKTVVTTTVTDSLSTPEGTLVTSMTVSKEYSTKDKVKLMKFTKPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARRGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWACLKWDDMAAKAPPGGGTTRTETTETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKQIPVAGVAATVTTASSTTSTVSTPQKVVVGPLAGPVPTGTKVVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSSTGVVQVQQKVLGIIPSTTGASQTFTSFQPRTATVTIRPNTTGTLGTTSTSQVMQGTPLRPGMTVIRTPLQQSTLGKTIIRTPLVVQQGILPASQSQQVVTQIIRGQPVSTAVSSTSTASTSSGQKTVTSPGTPPQQIQPQTASQPPRPQQGQVKLTMAQLTQLTQGQGGSQGLTVVIQGQGQTTGQLQLIPQGVTVIPGPGQQLMQAAMPNGTIQRFLFTPLPAAATTASTTTTTASTSTSATEQKQALQAQPASVLPPVQPQPQSQQQSQPQAQNQSAQPVSPTQPQAPQPPLQPETQTQLESQTPASLDSPVTPETQSSKSPVQSPAQTQAQGQSPTQVQSQPQSAVLPQGQSQVQPQQPAQVQTTTQQQIQMQPHAPIQIQPQLQQLQPQVQTSVSTLPTTQSLNQVPVQSPTRPQLQLQQPPTKVITVPQLQQQVQVLSQLQSHVVAQIQAQQGSVPQQIKLQLPIQIQQSSPVQAHQIQNVVTVQAASVQEQLQRVQQLREQQQKKKQQQIEIKREHTLQASNQSDIIQKQVVMKQNAVIEHLKQKKTLTPTEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLKAEILKKRALLDKELQIEVQEELKRDLTKIKKEKEKAQAAAAAAAAAAAAAAAAASATPPPPPPPLPSPPQHHTASVTSSSSTTVPVPISSQKRKRDEERDLSASKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLSPLTDKDYEGLRRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERILKRYYKKVTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 2944, "header": "tr|A0A8V1AJJ3-1|A0A8V1AJJ3_CHICK Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Gallus gallus OX=9031 GN=BPTF PE=1 SV=1 CANONICAL=A0A8V1AHH6-1" }, "locus": { "chromosome": "18", "start_pos": 7676174, "end_pos": 7631002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070915.1", "url": "https://www.ensembl.org/id/ENSGALT00010070915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043606.1", "url": "https://www.ensembl.org/id/ENSGALP00010043606.1" } ] } }, { "isoform_ac": "A0A8V1ALL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6/entry#A0A8V1ALL6-1", "sequence": { "sequence": "MVSDEEEEADPEDNQDSEEEEEEEIMEEEDDDDSDYPEEMEDEDDASYCTESSFRSHSTYSSTPGRRRQRVHRPRSPILEEKDIPPLEFPKSSEDLMVPSEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHIVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQETEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRHRRKYWFLNRRIIIEEDSESEKDKKVWYYSTKIQLAELIECLDKDYWEADLCKTLEEMREEVHRHMDVTEDLTNKARGTNKSFLSAANDEILDVIRARRGEIGEDRNTPADEAEKAKSDAENDQTDVEKSKEESGDQEKTEDTPTEQSVEKVKNEEATVIGDKSNCLTSSTDDNNTNPSAGETSCSEGKNAMGCQSETPDSNNVAEKKVASELHQELSEETGQMIPTNSSASAAAPQADVENSSSSELSSGQNDSIKMPDDAENAEGGLQTSEDIGEKANGERSDSPGAGKGTPGSTRMLTRLRNPDSKLCQMKSQQVAAAAHEANKLNKENREVLVVNSQGEVSRMNTKREIVMKGNINNYFKLGQEGKYRVYHNQYATNSFALNKHQHREDHDKRRHLSHKFCLTTAGEFKWNGSVHGSKVLTISTLRLTIIQLENNIPASFLHPNWASHRSNWIKAVQMCSKPREFALALAILECAIKPVVMLPIWRESLGHTRLRRMTAIEREEKEKVKKKERKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVHRFMPKLPGNTNANYRKLLPTKNEDEKCNLDKRKGPIKVKIEKDRMKDSHDLQAKHKGDTSEAAEKVQVKEEKSHEEKVDTNSENLGHAKDKVEKEIDGENYKVIKEEPMDIDTKTESSIKDEDSHCKLDIINVSEGFHLRTCYKRKVKSSKLDGLLERRIKQFTLEEKQRLERMKLEASAKNGGIQSLSSQKNLDELQMKKVKEGSQSVTSSQNQTYVSDKIQREDTGQDCLPVSSISCMKTGEQDELSLPSTNRLSKREGQLLDEDSPQPSEGERSIQNDSKDNNSEPVAADKSQVQEDVTEHESSFVDDLKQTNTDGKVKWDVLETNEKPLKQKLPITRVSQKEYENSEPLITKSSCRKGALAIPDKTNTEGNSQQQSRDPEKNCMIKSNFEPLSFQESKLEKDIIPKKTESKSENKIAFHQKLVSKDIESLKTELISERDLGSQTLEHEDGAKVDEELLRSQLTEANGQKKGQELKVETNTINKYLDQTNLNSVTDKKNNKDEETEMDLEKDKSTFQMNGKDNDIKVLSNDESLVKVTYGATADDIEPRVNNINKSFPEHEMKPLTSKESSVKPFMNGDITTEDSADKNAVDPKSSLQSSPEFEAEKTLQPSEEAPKYVQKTEEKHLSPQRSSFLDTSSTPTHDFCKENNLSSETESMETEDTEDKKVTSSPVMSCEESSLSSDFADQNGLQTYKVEDVNGESKIKTVITEVTTTTSTVSTESKTVFKVAETLASNDEKTVVSSTENCAISTVTTTTTVTKLTTPATDSNVDVISVQEHRKTVVTTTVTDSLSTPEGTLVTSMTVSKEYSTKDKVKLMKFTKPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARRGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWACLKWDDMAAKAPPGGGTTRTETTETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKQIPVAGVAATVTTASSTTSTVSTPQKVVVGPLAGPVPTGTKVVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSSTATSTAATSATTIASTGQTFQISGSPVTMAGKVITKLPLPANSKIVAVNVPSTQGGVVQVQQKVLGIIPSTTGASQTFTSFQPRTATVTIRPNTTGTLGTTSTSQVMQGTPLRPGMTVIRTPLQQSTLGKTIIRTPLVVQQGILPASQSQQVVTQIIRGQPVSTAVSSTSTASTSSGQKTVTSPGTPPQQIQPQTASQPPRPQQGQVKLTMAQLTQLTQGQGGSQGLTVVIQGQGQTTGQLQLIPQGVTVIPGPGQQLMQAAMPNGTIQRFLFTPLPAAATTASTTTTTASTSTSATEQKQALQAQPASVLPPVQPQPQSQQQSQPQAQNQSAQPVSPTQPQAPQPPLQPETQTQLESQTPASLDSPVTPETQSSKSPVQSPAQTQAQGQSPTQVQSQPQSAVLPQGQSQVQPQQPAQVQTTTQQQIQMQPHAPIQIQPQLQQLQPQVQTSVSTLPTTQSLNQVPVQSPTRPQLQLQQPPTKVITVPQLQQQVQVLSQLQSHVVAQIQAQQGSVPQQIKLQLPIQIQQSSPVQAHQIQNVVTVQAASVQEQLQRVQQLREQQQKKKQQQIEIKREHTLQASNQSDIIQKQVVMKQNAVIEHLKQKKTLTPTEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLKAEILKKRALLDKELQIEVQEELKRDLTKIKKEKEKAQAAAAAAAAAAAAAAAAASATPPPPPPPLPSPPQHHTASVTSSSSTTVPVPISSQKRKRDEERDLSASKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLSPLTDKDYEGLRRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERILKRYYKKVTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS", "length": 2998, "header": "tr|A0A8V1ALL6-1|A0A8V1ALL6_CHICK Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Gallus gallus OX=9031 GN=BPTF PE=1 SV=1 CANONICAL=A0A8V1AHH6-1" }, "locus": { "chromosome": "18", "start_pos": 7676174, "end_pos": 7631002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070914.1", "url": "https://www.ensembl.org/id/ENSGALT00010070914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043605.1", "url": "https://www.ensembl.org/id/ENSGALP00010043605.1" } ] } }, { "isoform_ac": "A0A8V1AN57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH6/entry#A0A8V1AN57-1", "sequence": { "sequence": "MVSDEEEEADPEDNQDSEEEEEEEIMEEEDDDDSDYPEEMEDEDDASYCTESSFRSHSTYSSTPGRRRQRVHRPRSPILEEKDIPPLEFPKSSEDLMVPSEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHIVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQETEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRHRRKYWFLNRRIIIEEDSESEKDKKVWYYSTKIQLAELIECLDKDYWEADLCKTLEEMREEVHRHMDVTEDLTNKARGTNKSFLSAANDEILDVIRARRGEIGEDRNTPADEAEKAKSDAENDQTDVEKSKEESGDQEKTEDTPTEQSVEKVKNEEATVIGDKSNCLTSSTDDNNTNPSAGETSCSEGKNAMGCQSETPDSNNVAEKKVASELHQELSEETGQMIPTNSSASAAAPQADVENSSSSELSSGQNDSIKMPDDAENAEGGLQTSEDIGEKANGERSDSPGAGKGTPGSTRMLTRLRNPDSKLCQMKSQQVAAAAHEANKLNKENREVLVVNSQGEVSRMNTKREIVMKGNINNYFKLGQEGKYRVYHNQYATNSFALNKHQHREDHDKRRHLSHKFCLTTAGEFKWNGSVHGSKVLTISTLRLTIIQLENNIPASFLHPNWASHRSNWIKAVQMCSKPREFALALAILECAIKPVVMLPIWRESLGHTRLRRMTAIEREEKEKVKKKERKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVHRFMPKLPGNTNANYRKLLPTKNEDEKCNLDKRKGPIKVKIEKDRMKDSHDLQAKHKGDTSEAAEKVQVKEEKSHEEKVDTNSENLGHAKDKVEKEIDGENYKVIKEEPMDIDTKTESSIKDEDSHCKLDIINVSEGFHLRTCYKRKVKSSKLDGLLERRIKQFTLEEKQRLERMKLEASAKNGGIQSLSSQKNLDELQMKKVKEGSQSVTSSQNQTYVSDKIQREDTGQDCLPVSSISCMKTGEQDELSLPSTNRLSKREGQLLDEDSPQPSEGERSIQNDSKDNNSEPVAADKSQVQEDVTEHESSFVDDLKQTNTDGKVKWDVLETNEKPLKQKLPITRVSQKEYENSEPLITKSSCRKGALAIPDKTNTEGNSQQQSRDPEKNCMIKSNFEPLSFQESKLEKDIIPKKTESKSENKIAFHQKLVSKDIESLKTELISERDLGSQTLEHEDGAKVDEELLRSQLTEANGQKKGQELKVETNTINKYLDQTNLNSVTDKKNNKDEETEMDLEKDKSTFQMNGKDNDIKVLSNDESLVKVTYGATADDIEPRVNNINKSFPEHEMKPLTSKESSVKPFMNGDITTEDSADKNAVDPKSSLQSSPEFEAEKTLQPSEEAPKYVQKTEEKHLSPQRSSFLDTSSTPTHDFCKENNLSSETESMETEDTEDKKVTSSPVMSCEESSLSSDFADQNGLQTYKVEDVNGESKIKTVITEVTTTTSTVSTESKTVFKVAETLASNDEKTVVSSTENCAISTVTTTTTVTKLTTPATDSNVDVISVQEHRKTVVTTTVTDSLSTPEGTLVTSMTVSKEYSTKDKVKLMKFTKPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARRGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWACLKWDDMAAKAPPGGGTTRTETTETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPEAPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIESWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKQIPVAGVAATVTTASSTTSTVSTPQKVVVGPLAGPVPTGTKVVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSSTGVVQVQQKVLGIIPSTTGASQTFTSFQPRTATVTIRPNTTGTLGTTSTSQVMQGTPLRPGMTVIRTPLQQSTLGKTIIRTPLVVQQGQSQQVVTQIIRGQPVSTAVSSTSTASTSSGQKTVTSPGTPPQQIQPQTASQPPRPQQGQVKLTMAQLTQLTQGQGGSQGLTVVIQGQGQTTGQLQLIPQGVTVIPGPGQQLMQAAMPNGTIQRFLFTPLPAAATTASTTTTTASTSTSATEQKQALQAQPASVLPPVQPQPQSQQQSQPQAQNQSAQPVSPTQPQAPQPPLQPETQTQLESQTPASLDSPVTPETQSSKSPVQSPAQTQAQGQSPTQVQSQPQSAVLPQGQSQVQPQQPAQVVMKQNAVIEHLKQKKTLTPTEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLKAEILKKRALLDKELQIEVQEELKRDLTKIKKEKEKAQAAAAAAAAAAAAAAAAASATPPPPPPPLPSPPQHHTASVTSSSSTTVPVPISSQKRKRDEERDLSASKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEADLIDEYVCPQCQSTEDAMTVLSPLTDKDYEGLRRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERILKRYYKKVTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRL", "length": 2815, "header": "tr|A0A8V1AN57-1|A0A8V1AN57_CHICK Computationally mapped isoform of Bromodomain PHD finger transcription factor OS=Gallus gallus OX=9031 GN=BPTF PE=1 SV=1 CANONICAL=A0A8V1AHH6-1" }, "locus": { "chromosome": "18", "start_pos": 7676174, "end_pos": 7631786, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070912.1", "url": "https://www.ensembl.org/id/ENSGALT00010070912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043603.1", "url": "https://www.ensembl.org/id/ENSGALP00010043603.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2360, "start_aa": "Thr", "end_pos": 2360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2360", 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"A0A8V1AHH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH9/entry#names_and_taxonomy" } ] }, { "name": "beta-keratin-related protein-like", "type": "synonym", "evidence": [ { "id": "XP_015153861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153861" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015153861.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153861" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107055091", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH9", "locus": {} } ], "crossref": [ { "id": "A0A8V1AHH9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055091", "url": "https://www.ncbi.nlm.nih.gov/gene/107055091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107055091", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPCEVSC", "url": "https://omabrowser.org/oma/group/SPCEVSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHH9", "url": "https://www.orthodb.org/?gene=A0A8V1AHH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] 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"MSSGGQMMSSRCSSPCEVTCPQPYANVCSQPCVTSCGDSRAVVYPPPVVITFPGPILNSCPQESIVGTSFPAPIGGYSESGGSFSSGGSYGGGIGGSYGGGSSYGGGFGGSYGGGSSYGGGMGGSYGGGRSFGSGGSFGGRRSISSRSCYGGGFGGGSSYGGGSYGGGRSFGIGSCYGGSSSSGFRRSSGGSCGYF", "length": 196, "header": "tr|A0A8V1AHH9-1|A0A8V1AHH9_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC107055091 PE=3 SV=1 CANONICAL=A0A8V1AHH9-1" }, "locus": { "chromosome": "25", "start_pos": 1362769, "end_pos": 1362182, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069499.1", "url": "https://www.ensembl.org/id/ENSGALT00010069499.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042786.1", "url": "https://www.ensembl.org/id/ENSGALP00010042786.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107055091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055091", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHJ1-1", "uniprot_ac": "A0A8V1AHJ1", "uniprot_id": "A0A8V1AHJ1_CHICK", "mass": { "chemical_mass": 25453.0, "monoisotopic_mass": 25453.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AHJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AHJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AF54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERAEGRPGVEAQDGEVLVVLAGLQEVLRSGAFVDEVGVEDVEFVTLHDFGRGVIEVVVGLVVFVPLEARVHAVEEARFAGPVFVGPEVRLARQRHLHAELRLVCSHALLGLAEEDVVGALGGVACGEESPVRLSDAAGSGKDLTHLSMGLSCVPLTAQHTSRPLTACSGPASCSPGGQHSLQPCTPEHTRLPEPSWVLLPVTWSCWRSSSSRCVSSSASSTWASKGSSLVPSSRGLYFPAS", "length": 242, "header": "tr|A0A8V1AHJ1-1|A0A8V1AHJ1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AHJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ1/entry#A0A8V1AF54-1", "sequence": { "sequence": "RGEGEQSAGGCGSLSGAGRGDGGPPSPAVAVPLEVEPQLEDTVGKLAAEAVAVGIFPFPVDDLKGDVLIGRPGVEAQDGEVLVVLAGLQEVLRSGAFVDEVGVEDVEFVTLHDFGRGVIEVVVGLVVFVPLEARVHAVEEARFAGPVFVGPEVRLARQRHLHAELRLVCSHALLGLAEEDVVGALGGVACGEERRSCFTCSGAERDVRLLGLPQGSHSRTPPSPRSVSPSSP", "length": 232, "header": "tr|A0A8V1AF54-1|A0A8V1AF54_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AHJ1-1" }, "locus": { "chromosome": "28", "start_pos": 1456114, "end_pos": 1453411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068130.1", "url": "https://www.ensembl.org/id/ENSGALT00010068130.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041873.1", "url": "https://www.ensembl.org/id/ENSGALP00010041873.1" } ] } }, { "isoform_ac": "A0A8V1AHJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ1/entry#A0A8V1AHJ1-1", "sequence": { "sequence": "MERAEGRPGVEAQDGEVLVVLAGLQEVLRSGAFVDEVGVEDVEFVTLHDFGRGVIEVVVGLVVFVPLEARVHAVEEARFAGPVFVGPEVRLARQRHLHAELRLVCSHALLGLAEEDVVGALGGVACGEESPVRLSDAAGSGKDLTHLSMGLSCVPLTAQHTSRPLTACSGPASCSPGGQHSLQPCTPEHTRLPEPSWVLLPVTWSCWRSSSSRCVSSSASSTWASKGSSLVPSSRGLYFPAS", "length": 242, "header": "tr|A0A8V1AHJ1-1|A0A8V1AHJ1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AHJ1-1" }, "locus": { "chromosome": "28", "start_pos": 1456316, "end_pos": 1455065, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068128.1", "url": "https://www.ensembl.org/id/ENSGALT00010068128.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041872.1", "url": "https://www.ensembl.org/id/ENSGALP00010041872.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJR7-1", "uniprot_ac": "A0A8V1AJR7", "uniprot_id": "A0A8V1AJR7_CHICK", "mass": { "chemical_mass": 52196.0, "monoisotopic_mass": 52196.0 }, "refseq": { "ac": "XP_040509657", "name": "midnolin-A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509657" }, "gene_names": [ { "name": "MIDN", "type": "recommended", "evidence": [ { "id": "A0A8V1AJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7" } ] }, { "name": "MIDN", "type": "synonym", "evidence": [ { "id": "XP_040509657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509657" } ] } ], "protein_names": [ { "name": "Midnolin", "type": "synonym", "evidence": [ { "id": "A0A8V1AJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7/entry#names_and_taxonomy" } ] }, { "name": "midnolin-A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040509657", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509657" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509657" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIDN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7", "locus": { "chromosome": "28", "start_pos": 3503408, "end_pos": 3494295, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028738", "url": "https://www.ensembl.org/id/ENSGALG00010028738" } ] } } ], "crossref": [ { "id": "A0A8V1AJR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01804", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01804", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107055352", "url": "https://www.ncbi.nlm.nih.gov/gene/107055352", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PSHDIGQ", "url": "https://omabrowser.org/oma/group/PSHDIGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHJ3", "url": "https://www.orthodb.org/?gene=A0A8V1AHJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJR7", "url": "https://www.orthodb.org/?gene=A0A8V1AJR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23010", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23010", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23010:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23010:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040509657", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509657", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPQPGARSCSRGAAPCDPLPAERPVHLCIHTTTGARYEVAVPPDETVEGLKRRLSQRLKVPKERLALLHKDSRLSSGKLQDLGVVEGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVNDFLSGRSPLTLALRVGDHMMFVQLQLAAQQSSGQLQHRHVIASRGEAGATNGPHCRTLHGSTGSGFARIPVVPSCPQSPAPSPTPATPAPPVYCNAPHPAPVTAGMFRSHGAGAQTVNSSVVSSCSEVDCSMRGGSSPSSSPAPSARSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPQSLAQLRCQTQFSSSSSSSSSSSSSPPASPDLTTKTTSEPLPAAAASPPLHPVVQCQSQIRMCKPSGDRLRQTENRATRCKVERLQLLMQQKRLRRKARRDARAPYHWLPNRKSSRTNSNSSVSSEGSLDLDFEDSVWKPEVKADIKSEFVVA", "length": 488, "header": "tr|A0A8V1AJR7-1|A0A8V1AJR7_CHICK Isoform 1 of Midnolin OS=Gallus gallus OX=9031 GN=MIDN PE=4 SV=1 CANONICAL=A0A8V1AJR7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7/entry#A0A8V1AHJ3-1", "sequence": { "sequence": "MEPQPGARSCSRGAAPCDPLPAERPVHLCIHTTTGARYEVAVPPDETVEGLKRRLSQRLKVPKERLALLHKDSRLSSGKLQDLGVVEGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVNDFLSGRSPLTLALRVGDHMMFVQLQLAAQQSSGQLQHRHVIASRGEAGATNGPHCRTLHGSTGSGFARIPVVPSCPQSPAPSPTPATPAPPVYCNAPHPAPVTAGMFRSHGAGAQTVNSSVVSSCSEVDCSMRGGSSPSSSPAPSARSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPQSLAQLRCQTQFSSSSSSSSSSSSSPPASPDLTTKTTSEPRTRVGGEVTLTLTPPPPSLPPPTCDRPPTIPPYPPHHHPVEDGVLFLLAWARSPLLRMWLRWGGGRGERWELLLCPPPPFPLAQVLPLP", "length": 464, "header": "tr|A0A8V1AHJ3-1|A0A8V1AJR7_CHICK Computationally mapped isoform of Midnolin OS=Gallus gallus OX=9031 GN=MIDN PE=4 SV=1 CANONICAL=A0A8V1AJR7-1" }, "locus": { "chromosome": "28", "start_pos": 3502462, "end_pos": 3494300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069545.1", "url": "https://www.ensembl.org/id/ENSGALT00010069545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042806.1", "url": "https://www.ensembl.org/id/ENSGALP00010042806.1" } ] } }, { "isoform_ac": "A0A8V1AJR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7/entry#A0A8V1AJR7-1", "sequence": { "sequence": "MEPQPGARSCSRGAAPCDPLPAERPVHLCIHTTTGARYEVAVPPDETVEGLKRRLSQRLKVPKERLALLHKDSRLSSGKLQDLGVVEGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVNDFLSGRSPLTLALRVGDHMMFVQLQLAAQQSSGQLQHRHVIASRGEAGATNGPHCRTLHGSTGSGFARIPVVPSCPQSPAPSPTPATPAPPVYCNAPHPAPVTAGMFRSHGAGAQTVNSSVVSSCSEVDCSMRGGSSPSSSPAPSARSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPQSLAQLRCQTQFSSSSSSSSSSSSSPPASPDLTTKTTSEPLPAAAASPPLHPVVQCQSQIRMCKPSGDRLRQTENRATRCKVERLQLLMQQKRLRRKARRDARAPYHWLPNRKSSRTNSNSSVSSEGSLDLDFEDSVWKPEVKADIKSEFVVA", "length": 488, "header": "tr|A0A8V1AJR7-1|A0A8V1AJR7_CHICK Isoform 1 of Midnolin OS=Gallus gallus OX=9031 GN=MIDN PE=4 SV=1 CANONICAL=A0A8V1AJR7-1" }, "locus": { "chromosome": "28", "start_pos": 3502176, "end_pos": 3494300, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069544.1", "url": "https://www.ensembl.org/id/ENSGALT00010069544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042805.1", "url": "https://www.ensembl.org/id/ENSGALP00010042805.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 209, "start_aa": "Thr", "end_pos": 209, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr209", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABE3-1", "protein_name": "Midnolin", "gene_name": "MIDN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPQPGGARSCRRGAPGGACELGPAAETSSMSLAIHSTTGTRYELSVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAARGDPSMTTTPVSSPCRPVSSAARVPPVPSSPTPASSSVTAGSFRSHSASTTCPEQMDCSPPASAGASPTSPAGGSPTSRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLTQLRCHAQCTPASPAPDLAPKTTSCEKLAAAAPASLSQARLCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWPPSRKAGRSDSSSSGGGGSPSEASGLGLDFEDSVWKPEVNPDIKSEFVVA", "length": 460 }, "evidence": [ { "id": "A0A8V1AJR7", "url": "https://omabrowser.org/oma/group/A0A8V1AJR7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1MNV0-1", "protein_name": "Midnolin", "gene_name": "MIDN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPQPGGARSCRRGAPGGACELSPTAETAPMSLAIHSTTGTRYELSVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQPPAAPDLGRAGGGGFRKYRFILFKHPWHRQGPQNPQRGGERPQVTQRGGPGRAGLGTLRAGALGLTGLSLQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAATRGDPSMTTTPVSSPCRPVSSAARVPPVPTSPTPASSPVTAGSFRSHSASTTCPEQMDCSPAASTGASPTSPTGSSPTSRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLTQLRCHAQCTPDLGPKTTSCEKLAAAAPASLSQARLCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWPPSRKAGRSDSTGSGGGGSPSEAAGLGLDFEDSVWKPEVNPDIKSEFVVA", "length": 524 }, "evidence": [ { "id": "A0A8V1AJR7", "url": "https://omabrowser.org/oma/group/A0A8V1AJR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4AE48-1", "protein_name": "Midnolin", "gene_name": "Midn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPQPGGARSCRRGAPGGACELSTTAESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQPPATPGPGRAAGGGFRKYRLILFKRPWHRQGPQSPERGGERPQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAAARGDSSIATPVSSPCRPVSSAARVPPVSSSPSSPVSPSPVTAGTFQSHAASTTCPEQTDCSPPASSNTTSTPGSSPTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPASLTQLRCHAQCSPASPAPDLTPKTTSCEKLATPSLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGRSDSSSSGGGGSPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA", "length": 505 }, "evidence": [ { "id": "A0A8V1AJR7", "url": "https://omabrowser.org/oma/group/A0A8V1AJR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TPJ7-1", "protein_name": "Midnolin", "gene_name": "Midn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPQPGGARSCRRGAPGGACELNTATESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAAARGDSSVATPVSSPCRPVSSAARVPPVSSSPSSPVSPSPVTAGSFRSHAASTTCPEQMDCSPPASSSSTSTPGSSPTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLTQLRCHAQCSPASPAPDLTPKTTSCEKLAATSSTSLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGRSDSSSSGGGGGPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA", "length": 465 }, "evidence": [ { "id": "A0A8V1AJR7", "url": "https://omabrowser.org/oma/group/A0A8V1AJR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504T8-1", "protein_name": "Midnolin", "gene_name": "MIDN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAARGDPSIASPVSSPCRPVSSAARVPPVPTSPSPASPSPITAGSFRSHAASTTCPEQMDCSPTASSSASPGASTTSTPGASPAPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLAQLRCHAQCSPASPAPDLAPRTTSCEKLTAAPSASLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWSPSRKAGRSDSSSSGGGGSPSEASGLGLDFEDSVWKPEVNPDIKSEFVVA", "length": 468 }, "evidence": [ { "id": "A0A8V1AJR7", "url": "https://omabrowser.org/oma/group/A0A8V1AJR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NYU6-1", "protein_name": "Midnolin", "gene_name": "midn", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQHPSARSCSSRGAAPSCESVSGEPPMNLYIHSTTGTRFELSLPAEETVEGLKRRLSQRLKVPKERLALLHKETRLSSGKLQDLGITDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQPSGGPQLQHRHLISRGSSEGTTGLSHGASGSASGMARVSHNPHPHHPHQHPHHPNTTLPSNPAAFPPSPSIPSIPPMYSTSASGHCSPPPQPSQLPGSFLHSQQPSSACAPSPSSPSPAASCPEASCSAKTSGNCNTPLRSRKPGAIIESFVNHAPGVFSGTFSGTLHPNCQDSTGRPRRDIGTILQILNDLLSATRHYQGMPPSLTQLRYQTQCTSPNSPAPSPPPSPPHTTGLTGLPTTVPSETQPTLHPLVQCQSQIRMCKPPGDRLRQTENRATRCKVERLQLLMQQKRLRRKARRDSRAPYHWLPNRKAGRSNSNSSMSSEGSLDLDFEDSVWKPDVKADMKSEFIMA", "length": 509 }, "evidence": [ { "id": "A0A8V1AJR7", "url": "https://omabrowser.org/oma/group/A0A8V1AJR7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR7" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 100, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 209, 212 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 }, { "start_pos": 455, "end_pos": 457 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHJ4-1", "uniprot_ac": "A0A8V1AHJ4", "uniprot_id": "A0A8V1AHJ4_CHICK", "mass": { "chemical_mass": 36475.0, "monoisotopic_mass": 36475.0 }, "refseq": { "ac": "XP_015135463", "name": "cytoplasmic phosphatidylinositol transfer protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135463" }, "gene_names": [ { "name": "PITPNC1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ] }, { "name": "PITPNC1", "type": "synonym", "evidence": [ { "id": "XP_015135463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135463" } ] } ], "protein_names": [ { "name": "Cytoplasmic phosphatidylinositol transfer protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4/entry#names_and_taxonomy" } ] }, { "name": "Retinal degeneration B homolog beta", "type": "synonym", "evidence": [ { "id": "A0A8V1AHJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4/entry#names_and_taxonomy" } ] }, { "name": "cytoplasmic phosphatidylinositol transfer protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135463" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135463" } ] }, { "annotation": "Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidic acid (PA) between membranes. Binds PA derived from the phospholipase D signaling pathway and among the cellular PA species, preferably binds to the C16:0/16:1 and C16:1/18:1 PA species.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK7#function" }, { "database": "UniProtKB", "id": "ARBA00055461", "url": "https://www.uniprot.org/uniprotkb/ARBA00055461#function" }, { "database": "UniProtKB", "id": "A0A8V1AN70", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN70#function" }, { "database": "UniProtKB", "id": "A0A8V1AC94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC94#function" }, { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PITPNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AHJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08890", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08890", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859655", "url": "https://www.ncbi.nlm.nih.gov/gene/100859655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859655", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VENRPCE", "url": "https://omabrowser.org/oma/group/VENRPCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC94", "url": "https://www.orthodb.org/?gene=A0A8V1AC94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHJ4", "url": "https://www.orthodb.org/?gene=A0A8V1AHJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJK7", "url": "https://www.orthodb.org/?gene=A0A8V1AJK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALN0", "url": "https://www.orthodb.org/?gene=A0A8V1ALN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN70", "url": "https://www.orthodb.org/?gene=A0A8V1AN70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135463", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36435", "url": "https://www.rhea-db.org/rhea/36435", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38691", "url": "https://www.rhea-db.org/rhea/38691", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AC94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN70", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLMKEYRICMPLTVEEYRIGQLYMISKHSHEQSDRGEGVEVVQNEPYEDPNHGNGQLTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDNEAKDLEREVCFIDIASDEIPERYYKESEDPKYFKSQKTGRGQLKEGWRDTHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPEISISNISMPSSTRSAPSSAPSTPLSTDAPDFLTVPKDRPRKKSAPETLTLPDPEKKKN", "length": 313, "header": "tr|A0A8V1AHJ4-1|A0A8V1AHJ4_CHICK Isoform 1 of Cytoplasmic phosphatidylinositol transfer protein 1 OS=Gallus gallus OX=9031 GN=PITPNC1 PE=3 SV=1 CANONICAL=A0A8V1AHJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4/entry#A0A8V1AC94-1", "sequence": { "sequence": "MISKHSHEQSDRGEGVEVVQNEPYEDPNHGNGQLTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDNEAKDLEREVCFIDIASDEIPERYYKESEDPKYFKSQKTGRGQLKEGWRDTHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDDVREYEKNMHEKTNIKVCNQHSSTVDEIESHAKART", "length": 245, "header": "tr|A0A8V1AC94-1|A0A8V1AC94_CHICK Computationally mapped isoform of Cytoplasmic phosphatidylinositol transfer protein 1 OS=Gallus gallus OX=9031 GN=PITPNC1 PE=3 SV=1 CANONICAL=A0A8V1AHJ4-1" }, "locus": { "chromosome": "18", "start_pos": 7735081, "end_pos": 7697572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070927.1", "url": "https://www.ensembl.org/id/ENSGALT00010070927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043618.1", "url": "https://www.ensembl.org/id/ENSGALP00010043618.1" } ] } }, { "isoform_ac": "A0A8V1AHJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4/entry#A0A8V1AHJ4-1", "sequence": { "sequence": "MLMKEYRICMPLTVEEYRIGQLYMISKHSHEQSDRGEGVEVVQNEPYEDPNHGNGQLTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDNEAKDLEREVCFIDIASDEIPERYYKESEDPKYFKSQKTGRGQLKEGWRDTHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPEISISNISMPSSTRSAPSSAPSTPLSTDAPDFLTVPKDRPRKKSAPETLTLPDPEKKKN", "length": 313, "header": "tr|A0A8V1AHJ4-1|A0A8V1AHJ4_CHICK Isoform 1 of Cytoplasmic phosphatidylinositol transfer protein 1 OS=Gallus gallus OX=9031 GN=PITPNC1 PE=3 SV=1 CANONICAL=A0A8V1AHJ4-1" }, "locus": { "chromosome": "18", "start_pos": 7763627, "end_pos": 7697318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070929.1", "url": "https://www.ensembl.org/id/ENSGALT00010070929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043620.1", "url": "https://www.ensembl.org/id/ENSGALP00010043620.1" } ] } }, { "isoform_ac": "A0A8V1AJK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4/entry#A0A8V1AJK7-1", "sequence": { "sequence": "MLMKEYRICMPLTVEEYRIGQLYMISKHSHEQSDRGEGVEVVQNEPYEDPNHGNGQLTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDNEAKDLEREVCFIDIASDEIPERYYKESEDPKYFKSQKTGRGQLKEGWRDTHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDDVREYEKNMHEKTNIKVCNQHSSTVDEIESHAKART", "length": 268, "header": "tr|A0A8V1AJK7-1|A0A8V1AJK7_CHICK Computationally mapped isoform of Cytoplasmic phosphatidylinositol transfer protein 1 OS=Gallus gallus OX=9031 GN=PITPNC1 PE=3 SV=1 CANONICAL=A0A8V1AHJ4-1" }, "locus": { "chromosome": "18", "start_pos": 7763627, "end_pos": 7697572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070931.1", "url": "https://www.ensembl.org/id/ENSGALT00010070931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043622.1", "url": "https://www.ensembl.org/id/ENSGALP00010043622.1" } ] } }, { "isoform_ac": "A0A8V1ALN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4/entry#A0A8V1ALN0-1", "sequence": { "sequence": "MLMKEYRICMPLTVEEYRIGQLYMISKHSHEQSDRGEGVEVVQNEPYEDPNHGNGQLTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTIFDNEAKDLEREVCFIDIASDEIPERYYKESEDPKYFKSQKTGRGQLKEGWRDTHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPEISISNISMPSSTRSAPSSAPSTPLSTDAPDFLTVPKDRPRKKSAPETLTLPDPEKKKN", "length": 289, "header": "tr|A0A8V1ALN0-1|A0A8V1ALN0_CHICK Computationally mapped isoform of Phosphatidylinositol transfer protein cytoplasmic 1 OS=Gallus gallus OX=9031 GN=PITPNC1 PE=4 SV=1 CANONICAL=A0A8V1AHJ4-1" }, "locus": { "chromosome": "18", "start_pos": 7763627, "end_pos": 7697318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070930.1", "url": "https://www.ensembl.org/id/ENSGALT00010070930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043621.1", "url": "https://www.ensembl.org/id/ENSGALP00010043621.1" } ] } }, { "isoform_ac": "A0A8V1AN70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4/entry#A0A8V1AN70-1", "sequence": { "sequence": "MLGAGPQTAACLGYRIGQLYMISKHSHEQSDRGEGVEVVQNEPYEDPNHGNGQLTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDNEAKDLEREVCFIDIASDEIPERYYKESEDPKYFKSQKTGRGQLKEGWRDTHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDDVREYEKNMHEKTNIKVCNQHSSTVDEIESHAKART", "length": 265, "header": "tr|A0A8V1AN70-1|A0A8V1AN70_CHICK Computationally mapped isoform of Cytoplasmic phosphatidylinositol transfer protein 1 OS=Gallus gallus OX=9031 GN=PITPNC1 PE=3 SV=1 CANONICAL=A0A8V1AHJ4-1" }, "locus": { "chromosome": "18", "start_pos": 7762759, "end_pos": 7697572, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070928.1", "url": "https://www.ensembl.org/id/ENSGALT00010070928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043619.1", "url": "https://www.ensembl.org/id/ENSGALP00010043619.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859655", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q54VC7-1", "protein_name": "Phosphatidylinositol transfer protein 5", "gene_name": "pitE", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLIKEFRIPLPLTVEEYKVAQLFMVATISKKNTSLGEGIEVIENKPYADGATTGFFTRKIFHLGGRLPTWLRSFAPTSLQIEEKAWNAYPYCKTSYACPLLGDRFSVSIETRYEPDSGTQDNCLNLNSEELSIREVEHIDIVNDPIDEAHYKPEEDPKIFQSVKTGRGKLQNDWMKSTKPIMCCYKVCKVEFRCWGVQNKVENFIQRVALRDTFFMGHRQIFCWIDQWFDMDMESLREFEKKTNEEMKAQFHNNNNNNSNNSNNNNNNNTQPQRSSFFSRSTDGNK", "length": 287 }, "evidence": [ { "id": "A0A8V1AHJ4", "url": "https://omabrowser.org/oma/group/A0A8V1AHJ4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K4R4-1", "protein_name": "Cytoplasmic phosphatidylinositol transfer protein 1", "gene_name": "Pitpnc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLKEYRICMPLTVDEYKIGQLYMISKHSHEQSDRGEGVEVVQNEPFEDPHHGNGQFTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDSIFDSEAKDLEREVCFIDIACDEIPERYYKESEDPKHFKSEKTGRGQLREGWRDNHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGVFPPAISISSIALLPSSVRSAPSSAPSTPLSTDAPEFLSIPKDRPRKKSAPETLTLPDPEKKATLNLPGVYTSEKPCRPKSE", "length": 332 }, "evidence": [ { "id": "A0A8V1AHJ4", "url": "https://omabrowser.org/oma/group/A0A8V1AHJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9U9P7-1", "protein_name": "Cytoplasmic phosphatidylinositol transfer protein 1", "gene_name": "rdgBbeta", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLIKEYRVCMPLTVEEYKIGQLYMIARHSLEQSEEGEGVEVVENKPCEDPVHGKGQYTEKHIHLSSRLPYWIQAICPRVFYVIEKSWNYYPYTLTEYTCSFIPKLNVLIKTKYEDNNGSTENCLDLTEDELKVRTVDHLDIAFDEVSAKHYKKEEDPKFFKSEKTNRGPLIEGWRETDKPIMCSYKVVHASFEVWGLQTKVEDFIQRGIREILLLGHRQAFAWVDEWHGMTLEDVRAYERQKQAETNEKIHNTSGGANAAANAKEANDGDID", "length": 273 }, "evidence": [ { "id": "A0A8V1AHJ4", "url": "https://omabrowser.org/oma/group/A0A8V1AHJ4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9UKF7-1", "protein_name": "Cytoplasmic phosphatidylinositol transfer protein 1", "gene_name": "PITPNC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLKEYRICMPLTVDEYKIGQLYMISKHSHEQSDRGEGVEVVQNEPFEDPHHGNGQFTEKRVYLNSKLPSWARAVVPKIFYVTEKAWNYYPYTITEYTCSFLPKFSIHIETKYEDNKGSNDTIFDNEAKDVEREVCFIDIACDEIPERYYKESEDPKHFKSEKTGRGQLREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISISSIPLLPSSVRSAPSSAPSTPLSTDAPEFLSVPKDRPRKKSAPETLTLPDPEKKATLNLPGMHSSDKPCRPKSE", "length": 332 }, "evidence": [ { "id": "A0A8V1AHJ4", "url": "https://omabrowser.org/oma/group/A0A8V1AHJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ], "pmid": "" }, { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36435", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphate(in) = a 1,2-diacyl-sn-glycero-3-phosphate(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36435" } ] }, { "id": "38691", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "38691", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/38691" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHJ4" }, { "id": "PF02121", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidylinositol transfer protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 243, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 260, "end_pos": 262 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHK8-1", "uniprot_ac": "A0A8V1AHK8", "uniprot_id": "A0A8V1AHK8_CHICK", "mass": { "chemical_mass": 22814.0, "monoisotopic_mass": 22814.0 }, "refseq": { "ac": "XP_004950013", "name": "RING finger protein 222", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950013" }, "gene_names": [ { "name": "RNF222", "type": "recommended", "evidence": [ { "id": "A0A8V1AHK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8" } ] }, { "name": "RNF222", "type": "synonym", "evidence": [ { "id": "XP_004950013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950013" } ] } ], "protein_names": [ { "name": "RING finger protein 222", "type": "synonym", "evidence": [ { "id": "XP_004950013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950013" } ] }, { "name": "Ring finger protein 222", "type": "synonym", "evidence": [ { "id": "A0A8V1AHK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004950013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950013" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF222", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8", "locus": { "chromosome": "18", "start_pos": 2310664, "end_pos": 2314186, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029335", "url": "https://www.ensembl.org/id/ENSGALG00010029335" } ] } } ], "crossref": [ { "id": "cd16564", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16564", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101751367", "url": "https://www.ncbi.nlm.nih.gov/gene/101751367", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042973", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042973", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101751367", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TRSFCCR", "url": "https://omabrowser.org/oma/group/TRSFCCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHK8", "url": "https://www.orthodb.org/?gene=A0A8V1AHK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47095:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47095:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004950013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950013", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTETSPSKEGAPAECPVCYEKFHPLEHTHRQLSCGHAFCHDCLVKCLLSAKLDGHIQNSIICPVCRYVTFLSKKKALWLSNPRTLEVPLSPSSLSQLTKLESSNALVVPSHFVVPVQSLERCSPTGAQGELARGAHIFIISRHGMPLVDTDCSSLRRESQAETRSTMSSSSALGLQCCQSPIALAVLLILTVALLAAVLPWLLLVKKDSQ", "length": 210, "header": "tr|A0A8V1AHK8-1|A0A8V1AHK8_CHICK Isoform 1 of Ring finger protein 222 OS=Gallus gallus OX=9031 GN=RNF222 PE=4 SV=1 CANONICAL=A0A8V1AHK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8/entry#A0A8V1AHK8-1", "sequence": { "sequence": "MTETSPSKEGAPAECPVCYEKFHPLEHTHRQLSCGHAFCHDCLVKCLLSAKLDGHIQNSIICPVCRYVTFLSKKKALWLSNPRTLEVPLSPSSLSQLTKLESSNALVVPSHFVVPVQSLERCSPTGAQGELARGAHIFIISRHGMPLVDTDCSSLRRESQAETRSTMSSSSALGLQCCQSPIALAVLLILTVALLAAVLPWLLLVKKDSQ", "length": 210, "header": "tr|A0A8V1AHK8-1|A0A8V1AHK8_CHICK Isoform 1 of Ring finger protein 222 OS=Gallus gallus OX=9031 GN=RNF222 PE=4 SV=1 CANONICAL=A0A8V1AHK8-1" }, "locus": { "chromosome": "18", "start_pos": 2312326, "end_pos": 2311697, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070946.1", "url": "https://www.ensembl.org/id/ENSGALT00010070946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043637.1", "url": "https://www.ensembl.org/id/ENSGALP00010043637.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101751367", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751367", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TJ06-1", "protein_name": "Ring finger protein 222", "gene_name": "RNF222", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSEGESKDSSGSECPVCYEKFRELQGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTIVCPICRYVTFLSRKSSRWPAKLDKSSQILAVPVGLPPSPLPDALGHANPLALSQPVWRSSPGQGGQLPLDPPPSLPREPQIFIISRHGMPLGEQDSVLPRRSLAELSGASLAPSSTRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQA", "length": 211 }, "evidence": [ { "id": "A0A8V1AHK8", "url": "https://omabrowser.org/oma/group/A0A8V1AHK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A6NCQ9-1", "protein_name": "RING finger protein 222", "gene_name": "RNF222", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEGESKDSSGSECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTLVCPICRYVTFLSKKSSRWPSMLDKSSQTLAVPVGLPSVPPLDSLGHTNPLAASSPAWRPPPGQARPPGSPGQSAQLPLDLLPSLPRESQIFVISRHGMPLGEQDSVLPRRSLAELSEASLAPRSARAFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQA", "length": 220 }, "evidence": [ { "id": "A0A8V1AHK8", "url": "https://omabrowser.org/oma/group/A0A8V1AHK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZTZ3-1", "protein_name": "Ring finger protein 222", "gene_name": "Rnf222", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEGESKDSSGSECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTIVCPICRYVTFLSKKSSRWPSMLDKSSQTLAVPVGLPSTPSPDRGGHTNPLVISHQVWRQSPSQGTQLPLDLLPSLPRESQIFIISRHGMPLGEQDSVLPRRSLAEISEASPAPSATRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQT", "length": 211 }, "evidence": [ { "id": "A0A8V1AHK8", "url": "https://omabrowser.org/oma/group/A0A8V1AHK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SSX3-1", "protein_name": "Ring finger protein 222", "gene_name": "RNF222", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEGESKDSSGSECPVCYERLRDLEGAGRTLSCGHVFCHDCLVKYLLSTCVDGQVQRTIVCPVCRYVTFLSKKSSRWPSKLDKSSQTLAVPVGLPPGPPPATLGHATPPATSPPAWGPSPSQSGQLPVDLPPGLPREPQIFVISRHGMPLGEQDSVLPRRSLAEVSEASPAPSSTRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQV", "length": 211 }, "evidence": [ { "id": "A0A8V1AHK8", "url": "https://omabrowser.org/oma/group/A0A8V1AHK8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GY46-1", "protein_name": "RING finger protein 222", "gene_name": "Rnf222", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEGESKDSSGSECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTIVCPICRYVTFLSKKSSRWPSMLDKSSQTLVVPVGLPSMPSPDRGGHTNPLAVSQQVWRQSPHQGTQLPLDLLPTTLPRESQIFIISRHGMPLGEQDSVLPRRSLAEISEASPAPSATRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQA", "length": 212 }, "evidence": [ { "id": "A0A8V1AHK8", "url": "https://omabrowser.org/oma/group/A0A8V1AHK8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CEF8-1", "protein_name": "RING finger protein 222", "gene_name": "Rnf222", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEGGSKDSSGSECPVCYEKFRDLDGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTIVCPICRYVTFLSKKSSRWPSMLDKSSQTLTVPVGLPSTPSPDRGGHTNPLVISHQVWRQSSSQGSQVPLDLLPSLPRESQIFIISRHGMPLGEQDSVLPRRSLAEISEASPAPSATRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQA", "length": 211 }, "evidence": [ { "id": "A0A8V1AHK8", "url": "https://omabrowser.org/oma/group/A0A8V1AHK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHM1-1", "uniprot_ac": "A0A8V1AHM1", "uniprot_id": "A0A8V1AHM1_CHICK", "mass": { "chemical_mass": 39707.0, "monoisotopic_mass": 39707.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM115", "type": "recommended", "evidence": [ { "id": "A0A8V1AHM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ] } ], "protein_names": [ { "name": "Transmembrane protein 115", "type": "synonym", "evidence": [ { "id": "A0A8V1AHM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM115", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1", "locus": { "chromosome": "12", "start_pos": 1542008, "end_pos": 1545172, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028130", "url": "https://www.ensembl.org/id/ENSGALG00010028130" } ] } } ], "crossref": [ { "id": "A0A8V1AHM1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHM1", "url": "https://www.orthodb.org/?gene=A0A8V1AHM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13377:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13377:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08551", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08551", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRYLPVARQHCVAALGGTSVVVKAVSGAVLLLYALSFALDTAYGLAVTPGFLFLPRCWLWTLLTHGLVERRAAGVALSLGTVAAAGRLLEPRWGALELLVFFAVVNASVGLLGAAAYFLTYAATFHVAYLFDVHIHGGLGFLAGVLVALKQTMGDSTVLRVPQVRMKAVPVLLLLLLAALRLATLIESPALASYGFGLLSSWVYLRFYQRHSRGRGDMSDHFAFATFFPEILQPAVGLAANLVHTLLVKVRLCRKTVKRYDVGAPSSITISLPGTDPQDAERRRQLALKALNERLKRVEDQTAWPSMEDEEEEVVVKSEGPLLPEASALGHEGISRRPGSEVSKQHHALSLLLCTQNLIFSFLD", "length": 365, "header": "tr|A0A8V1AHM1-1|A0A8V1AHM1_CHICK Isoform 1 of Transmembrane protein 115 OS=Gallus gallus OX=9031 GN=TMEM115 PE=1 SV=1 CANONICAL=A0A8V1AHM1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1/entry#A0A8V1AHM1-1", "sequence": { "sequence": "MRRYLPVARQHCVAALGGTSVVVKAVSGAVLLLYALSFALDTAYGLAVTPGFLFLPRCWLWTLLTHGLVERRAAGVALSLGTVAAAGRLLEPRWGALELLVFFAVVNASVGLLGAAAYFLTYAATFHVAYLFDVHIHGGLGFLAGVLVALKQTMGDSTVLRVPQVRMKAVPVLLLLLLAALRLATLIESPALASYGFGLLSSWVYLRFYQRHSRGRGDMSDHFAFATFFPEILQPAVGLAANLVHTLLVKVRLCRKTVKRYDVGAPSSITISLPGTDPQDAERRRQLALKALNERLKRVEDQTAWPSMEDEEEEVVVKSEGPLLPEASALGHEGISRRPGSEVSKQHHALSLLLCTQNLIFSFLD", "length": 365, "header": "tr|A0A8V1AHM1-1|A0A8V1AHM1_CHICK Isoform 1 of Transmembrane protein 115 OS=Gallus gallus OX=9031 GN=TMEM115 PE=1 SV=1 CANONICAL=A0A8V1AHM1-1" }, "locus": { "chromosome": "12", "start_pos": 1545083, "end_pos": 1543012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068169.1", "url": "https://www.ensembl.org/id/ENSGALT00010068169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041912.1", "url": "https://www.ensembl.org/id/ENSGALP00010041912.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 49, "start_aa": "Thr", "end_pos": 49, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr49", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ], "pmid": "" }, { "name": "Golgi transport complex", "id": "GO:0017119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017119", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 49 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHM4-1", "uniprot_ac": "A0A8V1AHM4", "uniprot_id": "A0A8V1AHM4_CHICK", "mass": { "chemical_mass": 127215.0, "monoisotopic_mass": 127215.0 }, "refseq": { "ac": "XP_015148271", "name": "voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148271" }, "gene_names": [ { "name": "CACNA2D2", "type": "recommended", "evidence": [ { "id": "A0A8V1AHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4" } ] }, { "name": "CACNA2D2", "type": "synonym", "evidence": [ { "id": "XP_015148271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148271" } ] } ], "protein_names": [ { "name": "Calcium voltage-gated channel auxiliary subunit alpha2delta 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4/entry#names_and_taxonomy" } ] }, { "name": "voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CACNA2D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4", "locus": { "chromosome": "12", "start_pos": 1547320, "end_pos": 1675085, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028132", "url": "https://www.ensembl.org/id/ENSGALG00010028132" } ] } } ], "crossref": [ { "id": "A0A8V1AHM4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038242", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038242", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "430150", "url": "https://www.ncbi.nlm.nih.gov/gene/430150", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430150", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430150", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQITNFR", "url": "https://omabrowser.org/oma/group/PQITNFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PIN9", "url": "https://www.orthodb.org/?gene=A0A1D5PIN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHM4", "url": "https://www.orthodb.org/?gene=A0A8V1AHM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10166:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10166:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112308", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112308", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-422356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5576892", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576892", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5576893", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576893", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PIN9", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PIN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMAAPTGSAAPVAPALCGHLALLLLLAAPAAHGYSFPQQHTMQYWARRLEQEIDGVMRIFGGVQQLRGIYNENRNLFEVKENVPRKLVEKVAGDIESLLAKKVRALKRLANAAEKFQKAHHWQDNIREEDIEYYDSKADTEFVSAVSTDDPDGEEIEREKSNSLKLEFTDDANFKTKVNYSYAAVQIPTDIYKGSTVILNELNWTQALEDVFIENRKEDPSLLWQVFGSATGVTRYYPATPWRAPNKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAKPVSCFKHLVQANIRNKKVFKEDVQGMVAKGTTDYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNKTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGNRAKQVQWTNVYQDALGLGLVVTGTLPVFNLTEDNSDRKNQLILGVMGIDVALNDIKKLTPRYNLGANGYVFAIDLNGYVLLHPNLQPQIINFREPVTLDFLDAELEDENKEEIRRSMIDGNDGQRFIKTLIKSLDEQYIDEVFRTYTWAPIKSTNYSLGLVLPPYSTYYIQANLSDQILQVKLPNIKMKDFEYLLPNSFESEGHVFIAPREYCKDLDLSDNNTEFLENFIALMEKVTPDSKQCDNFLLHNLILDTGITQQLVERVWKDQDLNTYSLLAVFAATDGGITRVFPNKAADDWEEEPEPFNASFYRRSLDNKGYIFKPPYRDDGYRGLDLENNTIGILVSTAVELSIGGKTLKPAVVGVKLDLEAWAEKFKVLASNRTDRDQLGSRRCDPSSSCEMDCEANNKDLICVLIDDGGFLVLSNQEDHWYQVGKFFSEVDANLMSALYNNSFYARKESYDFQSVCAPEAQSNTGAAPRGVFVPTVADLLSLAWWTSAAAWSLFQQFLYSLTYSSWFQTEDVMADGMEARETSCIMKQTQYYFSTVNATYNAIIDCGNCSRLFHAQRLANTNLLFVVADKPLCSQCESVKLLQAEVRAPPRDPNQCELVDRPRYRKGPHICFDYNATEDTSDCGRGASFTPSLGVLLSLQLLLLYASTSRHPLPPAACL", "length": 1126, "header": "tr|A0A8V1AHM4-1|A0A8V1AHM4_CHICK Isoform 1 of Calcium voltage-gated channel auxiliary subunit alpha2delta 2 OS=Gallus gallus OX=9031 GN=CACNA2D2 PE=3 SV=1 CANONICAL=A0A8V1AHM4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PIN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4/entry#A0A1D5PIN9-1", "sequence": { "sequence": "MAMAAPTGSAAPVAPALCGHLALLLLLAAPAAHGYSFPQQHTMQYWARRLEQEIDGVMRIFGGVQQLRGIYNENRNLFEVKENVPRKLVEKVAGDIESLLAKKVRALKRLANAAEKFQKAHHWQDNIREEDIEYYDSKADTEFVSAVSTDDPDGEEIEREKSNSLKLEFTDDANFKTKVNYSYAAVQIPTDIYKGSTVILNELNWTQALEDVFIENRKEDPSLLWQVFGSATGVTRYYPATPWRAPNKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAKPVSCFKHLVQANIRNKKVFKEDVQGMVAKGTTDYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNKTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGNRAKQVQWTNVYQDALGLGLVVTGTLPVFNLTEDNSDRKNQLILGVMGIDVALNDIKKLTPRYNLGANGYVFAIDLNGYVLLHPNLQPQIINFREPVTLDFLDAELEDENKEEIRRSMIDGNDGQRFIKTLIKSLDEQYIDEVFRTYTWAPIKSTNYSLGLVLPPYSTYYIQANLSDQILQVKYFEYLLPNSFESEGHVFIAPREYCKDLDLSDNNTEFLENFIALMEKVTPDSKQCDNFLLHNLILDTGITQQLVERVWKDQDLNTYSLLAVFAATDGGITRVFPNKAADDWEEEPEPFNASFYRRSLDNKGYIFKPPYRDDGYRGLDLENNTIGILVSTAVELSIGGKTLKPAVVGVKLDLEAWAEKFKVLASNRTDRDQLGSRRCDPSSSCEMDCEANNKDLICVLIDDGGFLVLSNQEDHWYQVGKFFSEVDANLMSALYNNSFYARKESYDFQSVCAPEAQSNTGAAPRGVFVPTVADLLSLAWWTSAAAWSLFQQFLYSLTYSSWFQTEDVMADGMEARETSCIMKQTQYYFSTVNATYNAIIDCGNCSRLFHAQRLANTNLLFVVADKPLCSQCESVKLLQAEVRAPPRDPNQCELVDRPRYRKGPHICFDYNATEDTSDCGRGASFTPSLGVLLSLQLLLLYASTSRHPLPPAACL", "length": 1119, "header": "tr|A0A1D5PIN9-1|A0A1D5PIN9_CHICK Computationally mapped isoform of Calcium voltage-gated channel auxiliary subunit alpha2delta 2 OS=Gallus gallus OX=9031 GN=CACNA2D2 PE=3 SV=2 CANONICAL=A0A8V1AHM4-1" }, "locus": { "chromosome": "12", "start_pos": 1674903, "end_pos": 1547948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068176.1", "url": "https://www.ensembl.org/id/ENSGALT00010068176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041919.1", "url": "https://www.ensembl.org/id/ENSGALP00010041919.1" } ] } }, { "isoform_ac": "A0A8V1AHM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4/entry#A0A8V1AHM4-1", "sequence": { "sequence": "MAMAAPTGSAAPVAPALCGHLALLLLLAAPAAHGYSFPQQHTMQYWARRLEQEIDGVMRIFGGVQQLRGIYNENRNLFEVKENVPRKLVEKVAGDIESLLAKKVRALKRLANAAEKFQKAHHWQDNIREEDIEYYDSKADTEFVSAVSTDDPDGEEIEREKSNSLKLEFTDDANFKTKVNYSYAAVQIPTDIYKGSTVILNELNWTQALEDVFIENRKEDPSLLWQVFGSATGVTRYYPATPWRAPNKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAKPVSCFKHLVQANIRNKKVFKEDVQGMVAKGTTDYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNKTVRVFTFSVGQHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGNRAKQVQWTNVYQDALGLGLVVTGTLPVFNLTEDNSDRKNQLILGVMGIDVALNDIKKLTPRYNLGANGYVFAIDLNGYVLLHPNLQPQIINFREPVTLDFLDAELEDENKEEIRRSMIDGNDGQRFIKTLIKSLDEQYIDEVFRTYTWAPIKSTNYSLGLVLPPYSTYYIQANLSDQILQVKLPNIKMKDFEYLLPNSFESEGHVFIAPREYCKDLDLSDNNTEFLENFIALMEKVTPDSKQCDNFLLHNLILDTGITQQLVERVWKDQDLNTYSLLAVFAATDGGITRVFPNKAADDWEEEPEPFNASFYRRSLDNKGYIFKPPYRDDGYRGLDLENNTIGILVSTAVELSIGGKTLKPAVVGVKLDLEAWAEKFKVLASNRTDRDQLGSRRCDPSSSCEMDCEANNKDLICVLIDDGGFLVLSNQEDHWYQVGKFFSEVDANLMSALYNNSFYARKESYDFQSVCAPEAQSNTGAAPRGVFVPTVADLLSLAWWTSAAAWSLFQQFLYSLTYSSWFQTEDVMADGMEARETSCIMKQTQYYFSTVNATYNAIIDCGNCSRLFHAQRLANTNLLFVVADKPLCSQCESVKLLQAEVRAPPRDPNQCELVDRPRYRKGPHICFDYNATEDTSDCGRGASFTPSLGVLLSLQLLLLYASTSRHPLPPAACL", "length": 1126, "header": "tr|A0A8V1AHM4-1|A0A8V1AHM4_CHICK Isoform 1 of Calcium voltage-gated channel auxiliary subunit alpha2delta 2 OS=Gallus gallus OX=9031 GN=CACNA2D2 PE=3 SV=1 CANONICAL=A0A8V1AHM4-1" }, "locus": { "chromosome": "12", "start_pos": 1674903, "end_pos": 1547948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068174.1", "url": "https://www.ensembl.org/id/ENSGALT00010068174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041917.1", "url": "https://www.ensembl.org/id/ENSGALP00010041917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:430150", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430150", "resource": "KEGG Pathway" }, { "id": "R-GGA-112308", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112308", "resource": "Reactome", "description": "Presynaptic depolarization and calcium channel opening" }, { "id": "R-GGA-422356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "resource": "Reactome", "description": "Regulation of insulin secretion" }, { "id": "R-GGA-5576892", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576892", "resource": "Reactome", "description": "Phase 0 - rapid depolarisation" }, { "id": "R-GGA-5576893", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576893", "resource": "Reactome", "description": "Phase 2 - plateau phase" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6PHS9-1", "protein_name": "Voltage-dependent calcium channel subunit alpha-2/delta-2", "gene_name": "Cacna2d2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVPARTCGASWPGPVRTARPWPGRGPRPCPDPRGPASGPARPLLLLLPPLLLLPLLTAPGASAYSFPQQHTMQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKAHRWQDNIKEEDIMYYDAKADAELDDPESEDMERGSKTSALRLDFIEDPNFKNKVNYSYTAVQIPTDIYKGSTVILNELNWTEALENVFIENRRQDPTLLWQVFGSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACTNKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKDAKQVQWTNVYEDALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGDKGHKQIRTLVKSLDERYIDEVIRNYTWVPIRSTNYSLGLVLPPYSTYYLQANLSDQILQVKLPISKLKDFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLDNHGYIFKPPHQDSLLRPLELENDTVGVLVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPSSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTIADFLNLAWWTSAAAWSLFQQLLYGLIYHSWFQADPAEAEGSPETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQCEAGRLLQKETHSDGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVHSFAASRHL", 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"https://www.uniprot.org/uniprotkb/A0A8V1AHM4" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHM4" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", 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"snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHN3-1", "uniprot_ac": "A0A8V1AHN3", "uniprot_id": "A0A8V1AHN3_CHICK", "mass": { "chemical_mass": 212192.0, "monoisotopic_mass": 212192.0 }, "refseq": { "ac": "XP_040505300", "name": "nuclear pore complex protein Nup214 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505300" }, "gene_names": [ { "name": "NUP214", "type": "recommended", "evidence": [ { "id": "A0A8V1AHN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ] }, { "name": "NUP214", "type": "synonym", "evidence": [ { "id": "XP_040505300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505300" } ] } ], "protein_names": [ { "name": "Nuclear pore complex protein Nup214", "type": "recommended", "evidence": [ { "id": "A0A8V1AHN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3/entry#names_and_taxonomy" } ] }, { "name": "214 kDa nucleoporin", "type": "synonym", "evidence": [ { "id": "A0A8V1AHN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3/entry#names_and_taxonomy" } ] }, { "name": "Nucleoporin Nup214", "type": "synonym", "evidence": [ { "id": "A0A8V1AHN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup214 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040505300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505300" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505300" } ] }, { "annotation": "Part of the nuclear pore complex. Has a critical role in nucleocytoplasmic transport. May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3#function" }, { "database": "UniProtKB", "id": "ARBA00055090", "url": "https://www.uniprot.org/uniprotkb/ARBA00055090#function" }, { "database": "UniProtKB", "id": "A0A8V1AFA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP214", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3", "locus": { "chromosome": "17", "start_pos": 6737399, "end_pos": 6698346, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028137", "url": "https://www.ensembl.org/id/ENSGALG00010028137" } ] } } ], "crossref": [ { "id": "427760", "url": "https://www.ncbi.nlm.nih.gov/gene/427760", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427760", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427760", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WLSTFQF", "url": "https://omabrowser.org/oma/group/WLSTFQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFA3", "url": "https://www.orthodb.org/?gene=A0A8V1AFA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHN3", "url": "https://www.orthodb.org/?gene=A0A8V1AHN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23193:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23193:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16755", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16755", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "database": 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"R-GGA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040505300", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505300", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEDGDLVPEREMKDFQFRALKKVRIFDPPDDLPKERSSLLVVSNKYGLVFAGGGTSLQIFHTRDLLMQNQLGEDPNNIVENVQGTSVPMKFPVQHLALSCDNLTLSVCMMSSDIGSFIGFFDVRTFFNQAKQQKRMFAYHKLAKDSGNAAMVNDLKWNPASPTMVAVCLSDGSISVLQVTDSVKVYATLPPSVAVTSVCWSPKGKQLAVGRQNGTVVQYLPNLQEKKVIPYPPFYQADNPVKVLDVLWIGTYVFAIVYAAADGTLETPPEVVVAILPKKEEKRPEKFVNFMEPCYGSCAERQHHYYLNYVEEWDLILAASAASTEVSILARQGDQNWESWILEDSSRAELPVTDKSDDTLPVGVAVDYTNNMPIPISDEKTLPPAPVLILLSTDGVLCPFYMINQNPGVRSLLVTPEPLPAAGERAPKSPGSTVTAPTTPPTSLKPDAVPAVAPAPSQPPAGDGAAAFSFTPSTAKVPSSTGSELPPYPFATDTSKQVLAPSLTGAATFSFSSASPKASITPAPSVGTTAATATSFSFGSINLKPSAESSPGLPHSTAPAAQKSSFVPSASSVKVNLNEKFTAVDTSSPTTSSGPTSSTMFSFSTTSKTVSGGPLSQPVTLSASPTTPLKTSTPAPAAMARPAQNVPAASLLQKTAKTTPSAAKPGSTQGKSALSSAALDKPAHQWKDSDPVIAGIREEIAHFQKEMEELKARTSKACFQVGTPEEMKTLRTESDDLHTFLLEIKETTESLHGDISTLKTTLLEGFAGVEEAREQNERNHSLGYLHLLYKKPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQERKQKRLIVPERETLFNTLANNREIINQQKKRLNQLVNSLQQLRLYNQTSQWSVPSDTSSPSSTQSFDSDLESLRSALMKTTLESRAKPPPKAPAKLSPVKLTQLRNFLAKRKTPPVRSMAPASLSRSAFLSTRYYEDLDEVSSTSSVSQSLENEDLQAADQEEEAAPIQVPRHAPVVRTPSIQPGLVAQPPSFGKQHPSLGTLLPTSSNRIIPQGADSTMLATKTVKHGAPAPTVTVPAPQAAAAAALRRQMATQSPAVSTSLTESTLKNVPQVVNVRELKTGALTPAVSTVIGSSVPHSAAQAVHQVLASVATNQAKQTPQTSSLKGQAPPSSVSASCPVASTPGPTSSGNKISGQGTAKTVTAVTSTVASVPATSAQPNKAFSFSSVGSGFNFGVVTSAASSPTLPSLAASQAPAKESTQPDSFSLAGGSKFGAVPESSFAFGSLKPASASGAAVANSSSADGTQSNKPAATMSSAPSTASGKLDIPQSKPGDTLFLSSLSGETLGSFSGLRVGQADDNAKTTTKTPSTSAAGAQSTKASTSPSGFVFGSPLMLGKAGEATSTSVTSAGTAPTSISTSATGSLFGNVQITNTGSPGVFNLAGSSGNKLNFSFGIQQASSMSTSTSAPSALPASTSLSFGNLLSPSQTAAPAASSIKGGGDAKLLSASEKTAENEAPESSPPTTQTPQPQIQLSEPVKEPPASQTAAGDTSTVGSSTASVAPPPDAIATPASTSELKAPVPPAASASVPQDQSISEAASATTIASPAEAASTLTAAAGVPTCVQSPAVGASVFVATSAGSSVFSQPPNSSSSGSAFSQPAGDTTATPSTPSVFGQLPAGTTASAPFGQPTTATVTTPTASTGFGTSAFGTTTTGGFGQPAFGQAPTFGQPASSSSSGFTFNQSGFGTVPAFGQPAASTAASSSGNVFGASSSTNSASSFSFGQPSASTGGGMFGQSNTLVFGQSSSFGQGGSVFGNTAAVTTTTSSAGFSFCQASGFGSSNTGSVFGQAANTGGIVFGQQSSSSTGGLFGSGSGGRGGGFFTGLGGKPSQDAANKNPFGSSSGGFGSAASQNSSSLFGNSGAKAFGFGNSSFGDQKPTGTFSSGGGSVASQGFGFSSPTKAGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPTFSSPLGSTGGKVFGEGTAAASAGGFGFGGTSNNTASFSTLANQNTPTFGSLSQQGTGFGTQNSGFSAFGTVGGGFGFGSTNTSSSGFSGWRS", "length": 2080, "header": "tr|A0A8V1AHN3-1|A0A8V1AHN3_CHICK Isoform 1 of Nuclear pore complex protein Nup214 OS=Gallus gallus OX=9031 GN=NUP214 PE=1 SV=1 CANONICAL=A0A8V1AHN3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3/entry#A0A8V1AFA3-1", "sequence": { "sequence": "MGEDGDLVPEREMKDFQFRALKKVRIFDPPDDLPKERSSLLVVSNKYGLVFAGGGTSLQIFHTRDLLMQNQLGEDPNNIVENVQGTSVPMKFPVQHLALSCDNLTLSVCMMSSDIGSFIGFFDVRTFFNQAKQQKRMFAYHKLAKDSGNAAMVNDLKWNPASPTMVAVCLSDGSISVLQVTDSVKVYATLPPSVAVTSVCWSPKGKQLAVGRQNGTVVQYLPNLQEKKVIPYPPFYQADNPVKVLDVLWIGTYVFAIVYAAADGTLETPPEVVVAILPKKEEKRPEKFVNFMEPCYGSCAERQHHYYLNYVEEWDLILAASAASTEVSILARQGDQNWESWILEDSSRAELPVTDKSDDTLPVGVAVDYTNNMPIPISDEKTLPPAPVLILLSTDGVLCPFYMINQNPGVRSLLVTPEPLPAAGERAPKSPGSTVTAPTTPPTSLKPDAVPAVAPAPSQPPAGDGAAAFSFTPSTAKASITPAPSVGTTAATATSFSFGSINLKPSAESSPGLPHSTAPAAQKSSFVPSASSVKVNLNEKFTAVDTSSPTTSSGPTSSTMFSFSTTSKTVSGGPLSQPVTLSASPTTPLKTSTPAPAAMARPAQNVPAASLLQKTAKTTPSAAKPGSTQGKSALSSAALDKPAHQWKDSDPVIAGIREEIAHFQKEMEELKARTSKACFQVGTPEEMKTLRTESDDLHTFLLEIKETTESLHGDISTLKTTLLEGFAGVEEAREQNERNHSLGYLHLLYKKPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQERKQKRLIVPERETLFNTLANNREIINQQKKRLNQLVNSLQQLRLYNQTSQWSVPSDTSSPSSTQSFDSDLESLRSALMKTTLESRAKPPPKAPAKLSPVKLTQLRNFLAKRKTPPVRSMAPASLSRSAFLSTRYYEDLDEVSSTSSVSQSLENEDLQAADQEEEAAPIQVPRHAPVVRTPSIQPGLVAQPPSFGKQHPSLGTLLPTSSNRIIPQGADSTMLATKTVKHGAPAPTVTVPAPQAAAAAALRRQMATQSPAVSTSLTESTLKNVPQVVNVRELKTGALTPAVSTVIGSSVPHSAAQAVHQVLASVATNQAKQTPQTSSLKGQAPPSSVSASCPVASTPGPTSSGNKISGQGTAKTVTAVTSTVASVPATSAQPNKAFSFSSVGSGFNFGVVTSAASSPTLPSLAASQAPAKESTQPDSFSLAGGSKFGAVPESSFAFGSLKPASASGAAVANSSSADGTQSNKPAATMSSAPSTASGKLDIPQSKPGDTLFLSSLSGETLGSFSGLRVGQADDNAKTTTKTPSTSAAGAQSTKASTSPSGFVFGSPLMLGKAGEATSTSVTSAGTAPTSISTSATGSLFGNVQITNTGSPGVFNLAGSSGNKLNFSFGIQQASSMSTSTSAPSALPASTSLSFGNLLSPSQTAAPAASSIKGGGDAKLLSASEKTAENEAPESSPPTTQTPQPQIQLSEPVKEPPASQTAAGDTSTVGSSTASVAPPPDAIATPASTSELKAPVPPAASASVPQDQSISEAASATTIASPAEAASTLTAAAGVPTCVQSPAVGASVFVATSAGSSVFSQPPNSSSSGSAFSQPAGDTTATPSTPSVFGQLPAGTTASAPFGQPTTATVTTPTASTGFGTSAFGTTTTGGFGQPAFGQAPTFGQPASSSSSGFTFNQSGFGTVPAFGQPAASTAASSSGNVFGASSSTNSASSFSFGQPSASTGGGMFGQSNTLVFGQSSSFGQGGSVFGNTAAVTTTTSSAGFSFCQASGFGSSNTGSVFGQAANTGGIVFGQQSSSSTGGLFGSGSGGRGGGFFTGLGGKPSQDAANKNPFGSSSGGFGSAASQNSSSLFGNSGAKAFGFGNSSFGDQKPTGTFSSGGGSVASQGFGFSSPTKAGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPTFSSPLGSTGGKVFGEGTAAASAGGFGFGGTSNNTASFSTLANQNTPTFGSLSQQGTGFGTQNSGFSAFGTVGGGFGFGSTNTSSSGFSGWRS", "length": 2039, "header": "tr|A0A8V1AFA3-1|A0A8V1AFA3_CHICK Computationally mapped isoform of Nuclear pore complex protein Nup214 OS=Gallus gallus OX=9031 GN=NUP214 PE=1 SV=1 CANONICAL=A0A8V1AHN3-1" }, "locus": { "chromosome": "17", "start_pos": 6737212, "end_pos": 6698376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068185.1", "url": "https://www.ensembl.org/id/ENSGALT00010068185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041928.1", "url": "https://www.ensembl.org/id/ENSGALP00010041928.1" } ] } }, { "isoform_ac": "A0A8V1AHN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3/entry#A0A8V1AHN3-1", "sequence": { "sequence": "MGEDGDLVPEREMKDFQFRALKKVRIFDPPDDLPKERSSLLVVSNKYGLVFAGGGTSLQIFHTRDLLMQNQLGEDPNNIVENVQGTSVPMKFPVQHLALSCDNLTLSVCMMSSDIGSFIGFFDVRTFFNQAKQQKRMFAYHKLAKDSGNAAMVNDLKWNPASPTMVAVCLSDGSISVLQVTDSVKVYATLPPSVAVTSVCWSPKGKQLAVGRQNGTVVQYLPNLQEKKVIPYPPFYQADNPVKVLDVLWIGTYVFAIVYAAADGTLETPPEVVVAILPKKEEKRPEKFVNFMEPCYGSCAERQHHYYLNYVEEWDLILAASAASTEVSILARQGDQNWESWILEDSSRAELPVTDKSDDTLPVGVAVDYTNNMPIPISDEKTLPPAPVLILLSTDGVLCPFYMINQNPGVRSLLVTPEPLPAAGERAPKSPGSTVTAPTTPPTSLKPDAVPAVAPAPSQPPAGDGAAAFSFTPSTAKVPSSTGSELPPYPFATDTSKQVLAPSLTGAATFSFSSASPKASITPAPSVGTTAATATSFSFGSINLKPSAESSPGLPHSTAPAAQKSSFVPSASSVKVNLNEKFTAVDTSSPTTSSGPTSSTMFSFSTTSKTVSGGPLSQPVTLSASPTTPLKTSTPAPAAMARPAQNVPAASLLQKTAKTTPSAAKPGSTQGKSALSSAALDKPAHQWKDSDPVIAGIREEIAHFQKEMEELKARTSKACFQVGTPEEMKTLRTESDDLHTFLLEIKETTESLHGDISTLKTTLLEGFAGVEEAREQNERNHSLGYLHLLYKKPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQERKQKRLIVPERETLFNTLANNREIINQQKKRLNQLVNSLQQLRLYNQTSQWSVPSDTSSPSSTQSFDSDLESLRSALMKTTLESRAKPPPKAPAKLSPVKLTQLRNFLAKRKTPPVRSMAPASLSRSAFLSTRYYEDLDEVSSTSSVSQSLENEDLQAADQEEEAAPIQVPRHAPVVRTPSIQPGLVAQPPSFGKQHPSLGTLLPTSSNRIIPQGADSTMLATKTVKHGAPAPTVTVPAPQAAAAAALRRQMATQSPAVSTSLTESTLKNVPQVVNVRELKTGALTPAVSTVIGSSVPHSAAQAVHQVLASVATNQAKQTPQTSSLKGQAPPSSVSASCPVASTPGPTSSGNKISGQGTAKTVTAVTSTVASVPATSAQPNKAFSFSSVGSGFNFGVVTSAASSPTLPSLAASQAPAKESTQPDSFSLAGGSKFGAVPESSFAFGSLKPASASGAAVANSSSADGTQSNKPAATMSSAPSTASGKLDIPQSKPGDTLFLSSLSGETLGSFSGLRVGQADDNAKTTTKTPSTSAAGAQSTKASTSPSGFVFGSPLMLGKAGEATSTSVTSAGTAPTSISTSATGSLFGNVQITNTGSPGVFNLAGSSGNKLNFSFGIQQASSMSTSTSAPSALPASTSLSFGNLLSPSQTAAPAASSIKGGGDAKLLSASEKTAENEAPESSPPTTQTPQPQIQLSEPVKEPPASQTAAGDTSTVGSSTASVAPPPDAIATPASTSELKAPVPPAASASVPQDQSISEAASATTIASPAEAASTLTAAAGVPTCVQSPAVGASVFVATSAGSSVFSQPPNSSSSGSAFSQPAGDTTATPSTPSVFGQLPAGTTASAPFGQPTTATVTTPTASTGFGTSAFGTTTTGGFGQPAFGQAPTFGQPASSSSSGFTFNQSGFGTVPAFGQPAASTAASSSGNVFGASSSTNSASSFSFGQPSASTGGGMFGQSNTLVFGQSSSFGQGGSVFGNTAAVTTTTSSAGFSFCQASGFGSSNTGSVFGQAANTGGIVFGQQSSSSTGGLFGSGSGGRGGGFFTGLGGKPSQDAANKNPFGSSSGGFGSAASQNSSSLFGNSGAKAFGFGNSSFGDQKPTGTFSSGGGSVASQGFGFSSPTKAGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPTFSSPLGSTGGKVFGEGTAAASAGGFGFGGTSNNTASFSTLANQNTPTFGSLSQQGTGFGTQNSGFSAFGTVGGGFGFGSTNTSSSGFSGWRS", "length": 2080, "header": "tr|A0A8V1AHN3-1|A0A8V1AHN3_CHICK Isoform 1 of Nuclear pore complex protein Nup214 OS=Gallus gallus OX=9031 GN=NUP214 PE=1 SV=1 CANONICAL=A0A8V1AHN3-1" }, "locus": { "chromosome": "17", "start_pos": 6737212, "end_pos": 6698376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068184.1", "url": "https://www.ensembl.org/id/ENSGALT00010068184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041927.1", "url": "https://www.ensembl.org/id/ENSGALP00010041927.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1068, "start_aa": "Thr", "end_pos": 1068, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1068", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1178, "start_aa": "Thr", "end_pos": 1178, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1178", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1182, "start_aa": "Thr", "end_pos": 1182, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1182", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1664, "start_aa": "Thr", "end_pos": 1664, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1664", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 597, "start_aa": "Thr", "end_pos": 597, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr597", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427760", "resource": "KEGG Pathway" }, { "id": "R-GGA-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-GGA-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-GGA-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-GGA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-GGA-1855170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "resource": "Reactome", "description": "IPs transport between nucleus and cytosol" }, { "id": "R-GGA-1855196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-GGA-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACK1-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "Nup214", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSVLTVSNKYGMLFAGGTNGLNVFPTKSLLIQNKPGDDPNKIVDTIQGLNVPMKFPVHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNQAKPLKRPFTYHKLSNGASGMVNDMKWNPTVPSMAAVCLADGSISVLQVTDVVKVCATLPPSSGVTCVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYEADHPVRVLDVLWIGTYVFTIVYAGADGALETCPDVVMALLPKKEEKHPEIFVNFMEPCYSSCTERQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQTNWESWVLEDSSRAELPVTDKSDDSLPVGVAIDYTNEVEVAINEEKTLPPAPVLLLLSTDGVLCPFYMINQNPGVRSLIKTLELISAEGERQPKSSGSFPSTPPSPQAPQNLDAPATASSPLPPVSAAPTATFPLPSAGGGPSVFSFGPSPFKSSSIPGEPPPYPTGSDSSRAAPASGTPTFSFAPPSKGTLAPTPAVAPVPTSAAPFTFGSSGFKPPLESTPMSSAPNTGMKPSFPPSTSSVKVNLNEKFTAVASSAPVHSSTSIPSVLPFSSSPKPPASGPLSHPTPLPASPSSMPLKPSVSPSPSVGRSAQTAPSSAPSTGQKSPRVNPPVPKSGSSQARALQPPVTEKQRHQWKESDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTPEEMKMLRTESDDLHTFLFEIREATESLHGDISTLKTTLLEGFAGVEEAREQHGRNHDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQKKRQRRLIVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYNQTSPWNRPSTLSTQSDTPSFDSDLEHLLKTTIESHTKPSPRVPGKLSPAKQAQLRNFLAKRKTPPVRSTAPVSSDSQSRPCPSSLAVKAPLSTEHLIHFCSSCFRLRCKIMKMLSELLVSVSPSAEMARLSGLLRVSNVVFGRAFVASLSRSAFLSQRYYEDLDEGSSASSVAHPLEGEDARPTPTCREEEAVVPVPRHAPVVRTPSVQPSLLPQAMPFAKPHLIHSSSPAAMSSSISTSATKVIPQGADTTMLATKTVKHGAPGPSHTVAAPQAAAAAALRRQMASQAPAVSTLTESTLKNVPQVVNVQELKSNPSPPSAAMGSSGPHSAAKAPHAVLTPVAASQAKQGSLINSFKPSGPTPVSCQLSSGDKAVGPGTAKTESPVTSTPSTGQLNKPFSFASPGTFTFGTITPAPSSSFTATPGAAPPTKESNQLEAFSFGGGGKPFCETIPGNPPATGPPSAPSTSVTTTSLEDSAPTSSKPATPETPVSTASSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQAEESTKPVSKASSTNLAGAQPAKPSGFSFPAASVLGKPVEPSVTSSAPAAPVSALSASTSSSSATVFGSVPLTSAAPSGLMSFSGASLASSKASFSFGNQQTSSAAAAAATPASTSVAPSLPASFPTLSFGGLLSSPSASSLPVSSGKITEEATPPAVPDKSDHSEVSASTPSLPLQPPSAQLPQASLQTSDPVKKEPVPAQTTDSRPSSSASLVASTESTPVAPGGPDSKTEAVSPASTFAGPGPAVVAAVLLGAGSAASEASGTPSTSSTVSSSTPTPATETAVFGTATSGSSVFTQPPAASSSSAFNQLSSNTATAPSATPVFGQVAASIASTAAATPQASSSGFGSPAFGASAPGVFGQTAFGQSPAFGQATSSPASGFSFSQPGFSSVPAFGQSVSSTPTSTSANVFGATSSTSSPGSFSFGQASTNTGGTLFGQNNPPAFGQSPGFGQGGSVFGSTSATTSTAAPSGFSFCQASGFGSSNTGSVFGQAASSGGSVFGQQSSTSSGSVFGSGNATRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTPTPNTSNLFGNSGAKTFGGFGSSFGEQKPAGTFSSGGGSVASQGFGFSTPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTASFGTLASQNAPTFGSLSQQTSGFGTPSSGFSGFGSGTGAFTFGSSNSSVQGFGGWRS", "length": 2143 }, "evidence": [ { "id": "A0A8V1AHN3", "url": "https://omabrowser.org/oma/group/A0A8V1AHN3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGLVFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHHLALSCDNLTLSACMMSSEYGSIIAFFDVRTFSNEAKQQKRPFAYHKLLKDAGGMVIDMKWNPTVPSMVAVCLADGSIAVLQVTETVKVCATLPSTVAVTSVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFAIVYAAADGTLETSPDVVMALLPKKEEKHPEIFVNFMEPCYGSCTERQHHYYLSYIEEWDLVLAASAASTEVSILARQSDQINWESWLLEDSSRAELPVTDKSDDSLPMGVVVDYTNQVEITISDEKTLPPAPVLMLLSTDGVLCPFYMINQNPGVKSLIKTPERLSLEGERQPKSPGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSPQAKSLQPAVAEKQGHQWKDSDPVMAGIGEEIAHFQKELEELKARTSKACFQVGTSEEMKMLRTESDDLHTFLLEIKETTESLHGDISSLKTTLLEGFAGVEEAREQNERNRDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDQHLEQKKKQRHLLVPERETLFNTLANNREIINQQRKRLNHLVDSLQQLRLYKQTSLWSLSSAVPSQSSIHSFDSDLESLCNALLKTTIESHTKSLPKVPAKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLESEDARTSCKDDEAVVQAPRHAPVVRTPSIQPSLLPHAAPFAKSHLVHGSSPGVMGTSVATSASKIIPQGADSTMLATKTVKHGAPSPSHPISAPQAAAAAALRRQMASQAPAVNTLTESTLKNVPQVVNVQELKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTAASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS", "length": 2090 }, "evidence": [ { "id": "A0A8V1AHN3", "url": "https://omabrowser.org/oma/group/A0A8V1AHN3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80U93-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "Nup214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSVLTISNKYGMLFAGGTNGLNVFPTKSLLIQNKPGDDPNKIVDTIQGLNVPMKFPVHHLALSCDSLTLSACMMSSEYGSIIAFFDVRTFSNQAKPLKRPFTYHKVSNDASGMVNDMKWNPTVPSMVAVCLADGSISVLQVTDVVKVCATLPPSTGVTCVCWSPKGKQLAVGKQNGTVVQYLPTLQEKKVIPCPPFYESDHPVRVLDVLWIGTYVFTIVYAGADGTLETCPDVVMALLPKKEEKHPEIFVNFMEPCYSSCTERQHHYYLSYIEEWDLVLAASAASTEVSILARQNDQTNWESWLLEDSSRAELPVTDKSDDSLPMGVAIDYTNEVEVTINEEKTLPPAPVLLLLSTDGVLCPFYMINQNPGVRSLIKTLELISTEGERQPKSSGSFPGTPSSPQAPQNLDAPATASSPLPPVSAAPTSTFPMPSAAGSPSVFSFGPSSFKSSASVTGEPPLYPTGSDSSRAAPGSGTSTFSFAPPSKGSLASTPAVAPVATSAAPFTFGFKPTLESTPMSSTPNTGMKPSFPPSASSVKVNLNEKFTAVASSAPVHSSTSTPSVLPFSSSPKPTASGPLSHPTPLPASSSSMPLKSSVSPSPAAGRSTQTAPSSAPSTGQKSPRVNPPVPKSGSSQAKALQPPVTEKQRPQWKDSDPVLAGIGEEIAHFQKELEELKARTAKACLQVGTSEEMKMLRTESDDLHTFLFEIRETTESLHGDISTLKTTLLEGFAGVEEAREQHGRNHDSGYLHLLYKRPLDPKSEAQLQEIRRLHQYVKFAVQDVNDVLDLEWDRHLEQKKRQRRLIVPERETLFNTLANNREIINQQRKRLNQLVDSLQQLRLYNHTAPWSLPSALSTQSNSHSFDSDLECLLKTTIESHTKPSPRVPGKLSPAKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEGSSASSVAQPLEGEDARPTCTSVAQPLEGEDAQPICKEEEAVVPVPRHAPVVRTPSIQPSLLPQSMPFAKPHLIHSSSPAVMSSAVSTSATKVIPQGADSTMLATKTVKHGAPGPSHTVAAPQAAAAAALRRQMASQAPAMSTLTESTLKTVPQVVNVQELRSNPSPPSAAMGSAVQHSAAKTPHAVLTPVANSQAKQGSLINSFKPSGPTAASCQLSSGDKAVGQGTAKTESAATSTPSAAGQLNKPFSFASPGTFTFGTITPTPSSSFTATPGAGPPTKEPTQLEAFSFGGGGKPFSEAIPGNSPATGATSAPSTSVTAASLEDSAPSSSKPAAPPETTVSSASSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQAEDSTKPVSKASSTNLAGAQPAKPSGVSFPNTSVLGKPVEPAVTSSVSPAPAAPASALNVSTSSSSATVFGSVPLTSAGPPGLISFGGAALASSKASFSFGNQQTSSSTASSATPTSTSVAPSLPASFPTLSFGGLLSSPSASSLPVSSGKSTEEAAPPAVPDKSDSSEVSATTPSLPVQPQSTQASLQTSDPVKKEPVLVQTTDSSPSRPASSASFVASTESMPVTLGAPDSKIEAVSPASTFAGPGQAAVATAVLPGAGSAATEASGTPTTSTVSSSSPTSATETAVFGTATSGSSVFTQPPAASSSSAFSQLSSNTATAPSATPVFGQVAASITSTAAATPQASSSGFGSPAFGASAPGVFGQTAFGQTPAFGQATSSPASGFSFSQPGFSSVPAFGQSVSSTPASTSANVFGATSSTSSPGSFSFGQASTNTGGTLFGQNNPPAFGQSPGFGQGSSVFGGTSATTSTAAPSGFSFCQASGFGSSNTGSVFGQAANTGGSVFGQSSTSSGGVFGSGNATRGGGFFSGLGGKPSQDAANKNPFSSAGGGFGSTAAPNTSNLFGNSGAKTFGGFGSSSFGEQKPAGTFSSGGGSVASQGFGFSTPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSGNTASFGTLASQNAPTFGSLSQQTSGFGTPSSGFAGFGSGTGAFTFGSSNSSVQGFGGWRS", "length": 2085 }, "evidence": [ { "id": "A0A8V1AHN3", "url": "https://omabrowser.org/oma/group/A0A8V1AHN3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W1X4-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "Nup214", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQNAPDCEDTQDFQFKLHHKIVAFKKCGEPRSNVNLLAVSSSRGLLFAGSPTQPELKVIIVKDLVNAKSTAQQPQARLVPLPSIPNYIACSSDGNLLAVNHTQNGTSLLSIYAVLSFMTPDVRPVYNIRLAAEDHVHGVQLLWNPVLPNSLAVVLSNGALAMYALKEGGNFEMHSLDKNQQVKCGCWSPKGKQIVLGFPGGTVKQFKPDLTLAKTLLCPPNIHDAPFDTIAIQWLSTFQFAVIFLQHGEDCSPSLYILNAPKAGAPSYINYYDICYSMNGPRNHQFVFSHVPQWNLLLVVSANGVEVGIMRSTEAGDTPAWQQLTLLDEARIEMPLSEDKDETFPLGFAFDTSTTHQLTINEKKLQTMPMVHVLSSDGELLSFNFLNVLPTAVSVCSPPPPVADTSGQFKPLNMLLASEEEEQPAWAASPSKAPAATPAASSDISFAFTPNTVTSTPAPSKDKQPSLFSGFGAAAAKAPAPQLSFGTAPTSSPVSFGAPTTNAAKPTTPFGGFGTQATTTAMGSMFSASGANAFGGMALNKPAIASVTPRTAAPGSTVPATPASAPANKPLYTVPLTFTPVDTKPATSAPPQIADESLKPDDTEPIIKDMIALQIEAFSKDIQKQKEQTKELLKGIAAPSALRAYAKRLDDLQELNEQAKDVEFELDVQGLRQGLNEAYAIVAECRGKLEIYRKPEITRLMNSSSCDPSGRRMLARLQSYVAANEAQLRLAQQHVDLQWEQFQDVVRRNSKSRMHMPCLEGIYQRLTRLQNLTSNQRIVQNNIKSKLKERGLLQAALLDQEKSRTRTNEAVDTLTDSILTMSLSQVVDSNAAKLTRERLQKIRNIVQLQKINVICPQRPDRVGLKSEVILETKRRAEQIKRAAAKPATANKYTQAAVAPPSPPDVAPTPAVAPMPQATVTVAPPLPKPMPSIPSVVEKPGVPTHPTTPVATPFSFSQSIPFVKTSTVTPTTNTVTPGEAAKPGLSIFGGSTISSFSFGGGAAKSALSFGTGSPAVAAPTPKPNPLSAVEKPTPEPTKPKEQKAAESKEFKAVQPETEESKVPQKPKAETENKSFGFGGFTGTGGTVGNTSSSPFSFGGLGSSLGFGGTAAAVPKSEPSSTATTSVATSASTAPFGIFSAALAKPSNSEPITTVTSNTTTITSKPTNVIASSSVTDAPSVTTTNAVTSSTDPIGGLFSSVTICKPNTPADTTKPANIFGGGLSAGSFSFGGTIDASKGLFGSTKPVATAPTSVTEANNKTDPISTTPSAISTTTATTTVSSPAVVPAAVTAAVPATSSTTVTSSTAVPGSAFSFSNAFSTLSAGGAAAPTTSASAPLAAKSPTATSTGNNSSNSVFGGGFAVATSTAAPVASPFQSAAKSPVSSANIFGSIPKAETSVFGGATTAPSNTTAAATPDAPPAGLFASAAISNPSPFGSPTTRAPASGGNIFGQAVKPSVFGQPAQAGDSGGSIFGGGSASTPFGSSSIFGGGNTQGAVGAPAAGSTSIFGQKVFGQSSAAAPAAGGNIFSNPVGSPQASPFGGGGNSIFGSPATAPPASGGSIFGGGSSSGGFGSFTQTTPAQGGFGGGFGQGGGGSVAQTGFGSPQAPQQQTTTPGGFGAKPVFGGSPAFGASPTFGGGATFGSPKGFGGFGGASPVASPPPFGAAAKPAQGNIFETLGGQESGLSFGNLAQTGNSNAQKPAFGGSSFMNYR", "length": 1711 }, "evidence": [ { "id": "A0A8V1AHN3", "url": "https://omabrowser.org/oma/group/A0A8V1AHN3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" }, { "name": "cytoplasmic side of nuclear pore", "id": "GO:1990876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990876", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" }, { "name": "regulation of nucleocytoplasmic transport", "id": "GO:0046822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046822", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" }, { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" }, { "name": "nuclear export signal receptor activity", "id": "GO:0005049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1293, "end_pos": 1295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1445, "end_pos": 1447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1643, "end_pos": 1645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1736, "end_pos": 1738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1907, "end_pos": 1909, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1924, "end_pos": 1926, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2020, "end_pos": 2022, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2069, "end_pos": 2071, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" }, { "id": "PF18617", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18617" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nuclear pore complex protein Nup214 phenylalanine-glycine (FG)", "eco_id": "ECO_0000259", "start_pos": 1906, "end_pos": 1966, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AHN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHN3" }, { "id": "PF16755", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16755" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoporin Nup159/Nup146 N-terminal", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 398, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 597, 1068, 1178, 1182, 1664 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 1293, "end_pos": 1295 }, { "start_pos": 1445, "end_pos": 1447 }, { "start_pos": 1643, "end_pos": 1645 }, { "start_pos": 1736, "end_pos": 1738 }, { "start_pos": 1907, "end_pos": 1909 }, { "start_pos": 1924, "end_pos": 1926 }, { "start_pos": 2020, "end_pos": 2022 }, { "start_pos": 2069, "end_pos": 2071 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 780, "end_pos": 782 }, { "start_pos": 880, "end_pos": 882 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], 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"categories": [ "Enzyme and Pathway" ] }, { "id": "AGPDCEC", "url": "https://omabrowser.org/oma/group/AGPDCEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFI7", "url": "https://www.orthodb.org/?gene=A0A8V1AFI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFJ2", "url": "https://www.orthodb.org/?gene=A0A8V1AFJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHP6", "url": "https://www.orthodb.org/?gene=A0A8V1AHP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHP9", "url": "https://www.orthodb.org/?gene=A0A8V1AHP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJW9", "url": "https://www.orthodb.org/?gene=A0A8V1AJW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJX4", "url": "https://www.orthodb.org/?gene=A0A8V1AJX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALQ1", "url": "https://www.orthodb.org/?gene=A0A8V1ALQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10574:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10574:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135244", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNACAAAGSAFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIECNCNQIGSLHDRCNETGYCECKEGATGPKCDDCLPNYYWRQGCFPNVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 527, "header": "tr|A0A8V1AJX4-1|A0A8V1AJX4_CHICK Isoform 1 of Netrin-G2 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4/entry#A0A8V1AFI7-1", "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNAYCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIECNCNQIGSLHDRCNETGYCECKEGATGPKCDDCLPNYYWRQGCFPNVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 518, "header": "tr|A0A8V1AFI7-1|A0A8V1AFI7_CHICK Computationally mapped isoform of Netrin-G1 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "locus": { "chromosome": "17", "start_pos": 7088441, "end_pos": 7053550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069613.1", "url": "https://www.ensembl.org/id/ENSGALT00010069613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042874.1", "url": "https://www.ensembl.org/id/ENSGALP00010042874.1" } ] } }, { "isoform_ac": "A0A8V1AFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4/entry#A0A8V1AFJ2-1", "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNACAAAGSAFGTVLSPTKVAAPEPKLKAPDPPKNIRAAPKSKAGRTAHSAGKRHGKKSASSKNSKLIRLQPDTGPVAPIETYKDCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIECNCNQIGSLHDRCNETGYCECKEGATGPKCDDCLPNYYWRQGCFPNVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 599, "header": "tr|A0A8V1AFJ2-1|A0A8V1AFJ2_CHICK Computationally mapped isoform of Netrin-G2 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "locus": { "chromosome": "17", "start_pos": 7088441, "end_pos": 7053550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069618.1", "url": "https://www.ensembl.org/id/ENSGALT00010069618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042879.1", "url": "https://www.ensembl.org/id/ENSGALP00010042879.1" } ] } }, { "isoform_ac": "A0A8V1AHP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4/entry#A0A8V1AHP6-1", "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNACAAAGSAFGTFERPQRVTTAKTTTAKTTPTTTTTTTTTTTTTSAPLPASTTTQPASIIRPASEPAASVPMKEKEEKAAVLSPTKVAAPEPKLKAPDPPKNIRAAPKSKAGRTAHSAGKRHGKKSASSKNSKLIRLQPDTGPVAPIETYKDCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIECNCNQIGSLHDRCNETGYCECKEGATGPKCDDCLPNYYWRQGCFPNVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 667, "header": "tr|A0A8V1AHP6-1|A0A8V1AJX4_CHICK Computationally mapped isoform of Netrin-G2 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "locus": { "chromosome": "17", "start_pos": 7088441, "end_pos": 7053550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069615.1", "url": "https://www.ensembl.org/id/ENSGALT00010069615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042876.1", "url": "https://www.ensembl.org/id/ENSGALP00010042876.1" } ] } }, { "isoform_ac": "A0A8V1AHP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4/entry#A0A8V1AHP9-1", "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNACAAAGSAFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIANVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 482, "header": "tr|A0A8V1AHP9-1|A0A8V1AHP9_CHICK Computationally mapped isoform of Netrin G2 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "locus": { "chromosome": "17", "start_pos": 7088441, "end_pos": 7053550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069620.1", "url": "https://www.ensembl.org/id/ENSGALT00010069620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042881.1", "url": "https://www.ensembl.org/id/ENSGALP00010042881.1" } ] } }, { "isoform_ac": "A0A8V1AJW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4/entry#A0A8V1AJW9-1", "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNACAAAGSAFGTFERPQRVTTAKTTTAKTTPTTTTTTTTTTTTTSAPLPASTTTQPASIIRPASEPAASVPMKEKEEKAGYPGLSAAAPLQVGSPPAKVGAAEAVLSPTKVAAPEPKLKAPDPPKNIRAAPKSKAGRTAHSAGKRHGKKSASSKNSKLIRLQPDTGPVAPIETYKDCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIECNCNQIGSLHDRCNETGYCECKEGATGPKCDDCLPNYYWRQGCFPNVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 691, "header": "tr|A0A8V1AJW9-1|A0A8V1AJW9_CHICK Computationally mapped isoform of Netrin-G2 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "locus": { "chromosome": "17", "start_pos": 7088441, "end_pos": 7053550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069614.1", "url": "https://www.ensembl.org/id/ENSGALT00010069614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042875.1", "url": "https://www.ensembl.org/id/ENSGALP00010042875.1" } ] } }, { "isoform_ac": "A0A8V1AJX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4/entry#A0A8V1AJX4-1", "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNACAAAGSAFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIECNCNQIGSLHDRCNETGYCECKEGATGPKCDDCLPNYYWRQGCFPNVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 527, "header": "tr|A0A8V1AJX4-1|A0A8V1AJX4_CHICK Isoform 1 of Netrin-G2 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "locus": { "chromosome": "17", "start_pos": 7088441, "end_pos": 7053550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069619.1", "url": "https://www.ensembl.org/id/ENSGALT00010069619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042880.1", "url": "https://www.ensembl.org/id/ENSGALP00010042880.1" } ] } }, { "isoform_ac": "A0A8V1ALQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4/entry#A0A8V1ALQ1-1", "sequence": { "sequence": "MLYLLALLLHRLPLAMGQYDICKSWVTTDDGPSWEFYACQPKAMRMKDYVTVRVDPAGITCGDPPERFCTHENPYLCSDECDASNPDLAHPPKLMFDSEDEGLATYWQSVTWRRYPEPLLANITLSWNKSIELTDDIVITFEYGRPTIMMLEKSLDNGRTWHPYQYYADDCMEAFSMPARRVRDLSTTSANRVLCTEEYSRWAGSKKEKTVRFEVRDRFAIFAGPDLKNMDNLYTRLESAKGLKDFFTVTDLRMRLLRPALGGTYVQRENLYKYFYAVSNIEVTGRCKCNLHANLCTFKEGSLQCECEHNTTGQDCGKCKKNFRSRSWRAGSYLPLPNGSPNACAAAGSAFGTFERPQRVTTAKTTTAKTTPTTTTTTTTTTTTTSAPLPASTTTQPAVLSPTKVAAPEPKLKAPDPPKNIRAAPKSKAGRTAHSAGKRHGKKSASSKNSKLIRLQPDTGPVAPIETYKDCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGFYRNSSAELDDENVCIECNCNQIGSLHDRCNETGYCECKEGATGPKCDDCLPNYYWRQGCFPNVCDDELLLCQNGGTCYQNQRCICPVGFKGVLCQQSRCEADRKDCDGASSTRAAISTVLLGVLGLQLRGWADL", "length": 644, "header": "tr|A0A8V1ALQ1-1|A0A8V1ALQ1_CHICK Computationally mapped isoform of Netrin-G2 OS=Gallus gallus OX=9031 GN=NTNG2 PE=4 SV=1 CANONICAL=A0A8V1AJX4-1" }, "locus": { "chromosome": "17", "start_pos": 7088441, "end_pos": 7053550, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069617.1", "url": "https://www.ensembl.org/id/ENSGALT00010069617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042878.1", "url": "https://www.ensembl.org/id/ENSGALP00010042878.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417171", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417171", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ADT9-1", "protein_name": "Netrin G2", "gene_name": "Ntng2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHLLALFLHCLPLVSGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDREDEGLATYWQSVTWSRYPSPLEANITLSWNKSVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSPSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRMESAKGLKEFFTFTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCTVREGSLQCECEHNTTGPDCGKCKKNFRTRAWRAGSYLPLPHGSPNACAAAGSAFGSQTKPTTVAPLGDSSFWPQVSSSAEAVTIPVAIPSQAKDSTLFQLKPRSPQVIPIEEFQDCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAVGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCQQNQRCACPPGYAGIRCEQPRCDLADDAGPDCDRAPGTVPRPDTLLGCLLLLGLAARLTC", "length": 589 }, "evidence": [ { "id": "A0A8V1AJX4", "url": "https://omabrowser.org/oma/group/A0A8V1AJX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4F1-1", "protein_name": "Netrin-G2", "gene_name": "Ntng2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRLLALFLHCLPLVSGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDREDEGLATYWQSVTWSRYPSPLEANITLSWNKSVELTDDVVVTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSPSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRMESAKGLKEFFTFTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCTVREGSLQCECEHNTTGPDCGRCKKNFRTRAWRAGSYLPLPHGSPNACAAAGSAFGSQTKPPTMAPLGDSSFWPQVSSSAEAVAISVAVPSQAKDSTLFELKPRSPQVIPIEEFQDCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAVGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCQQNQRCACPPGYTGIRCEQPRCDLADDAGPDCDRAPGIVPRPDTLLGCLLLLGLAARLAC", "length": 589 }, "evidence": [ { "id": "A0A8V1AJX4", "url": "https://omabrowser.org/oma/group/A0A8V1AJX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96CW9-1", "protein_name": "Netrin-G2", "gene_name": "NTNG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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} ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 453, "end_pos": 488, "start_aa": "Phe", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AJX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJX4" }, { "id": "PS50027", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin EGF-like", "eco_id": "ECO_0000259", "start_pos": 410, "end_pos": 454, "start_aa": "Cys", "end_aa": "Pro", 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[] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHP7-1", "uniprot_ac": "A0A8V1AHP7", "uniprot_id": "A0A8V1AHP7_CHICK", "mass": { "chemical_mass": 50925.0, "monoisotopic_mass": 50925.0 }, "refseq": {}, "gene_names": [ { "name": "ANGPTL4", "type": "recommended", "evidence": [ { "id": "A0A8V1AHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP7" } ] } ], "protein_names": [ { "name": "Angiopoietin like 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AHP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANGPTL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP7", "locus": { "chromosome": "28", "start_pos": 1263083, "end_pos": 1273435, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027751", "url": "https://www.ensembl.org/id/ENSGALG00010027751" } ] } } ], "crossref": [ { "id": "A0A8V1AHP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": 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"PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8963889", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8963889", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9762292", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9762292", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AHP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGDERALRGAFLGMGRIQSSGCPPPPRAALLLGHGLKEHVDRTKGQMRELGSRLSAHNSSMGRLLRQARETQEQGELLRASVRELEGRGRQLFNLSEALRQRLEEVAADKAEIQGRLEQLEGRVRQALQARPAENQSSKDLGALQTLMDAQNSRIEELLQKIKQQQYKLDKQNLQIKSLQSKVNLLIPLHPKDNKTQSPKWKINPKKSFSHTNQSHNVSVEPALPHKLPEDCQQLFLAGQQSSGVFQVQPSGSQPFKVYCDMTAEGGWTVIQRRTDGSVDFDQLWDAYKNGFGDLHGDFWLGLEKIHHLVQEGRYDLLIELEDWEGNSQEIQFEFSLGGESTAYTLNLLGPLSGELENAIGDFRQLPFSTRDRDHDLKADTNCAKHLSGGWWFSTCGHANLNGKYFRSIPRQRHERKQGIFWKTWKGRYYPLKSTTMKIQPAALEAEP", "length": 449, "header": "tr|A0A8V1AHP7-1|A0A8V1AHP7_CHICK Isoform 1 of Angiopoietin like 4 OS=Gallus gallus OX=9031 GN=ANGPTL4 PE=4 SV=1 CANONICAL=A0A8V1AHP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHP7/entry#A0A8V1AHP7-1", "sequence": { "sequence": 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] } ], "sequence": { "sequence": "MAAACACAVGAPGSSFAPHFFARERLPAALRRRLPRAAMGSKHIAQETFDDAVQENIAEFEMDPEEAVREAVQQFESQGVDLSNIIKAVRQPASENGQKQKHEVLLTLDSLGRCVADSDLTEMAEQLVVFTDQCKEQLAFRYLAGQNGAYPVVFSACQLASGDRNLMMKAFNTLSAILDGQPDLLDSAGQDLLLQTLKEYKEDAEMTLAGIRCIRHACLKHEQNRQDFVKGGVLPLLTGAIVLHGDSADVVRTASSALRIMTFDDDIRVPFGHAHDHAKMIVLENDGLRVLIEAAKAFTDNCSVLSELCATLSRLSVRNEFCQEIVDLGGLNFMVSLLADSIDHPDVVKQVLSAIRAIAGNDDVKDAIVTAGGTDLIVLAISHHLNNPQICEQGCAALCMLALRKPENCNVIMEGGGALAALQAMKAHPREVAVQKQACMLIRNLVSRSRDYSQPILEMGAEDLITEARATHKDCDDVAKAALRDLGCKVELRELWTGQKGSLAQ", "length": 505, "header": "tr|A0A8V1AHQ0-1|A0A8V1AHQ0_CHICK Isoform 1 of Armadillo repeat containing 6 OS=Gallus gallus OX=9031 GN=ARMC6 PE=1 SV=1 CANONICAL=A0A8V1AHQ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHQ0/entry#A0A8V1AFC6-1", "sequence": { "sequence": "MGSKHIAQETFDDAVQQFESQGVDLSNIIKAVRQPASENGQKQKHEVLLTLDSLGRCVADSDLTEMAEQLVVFTDQCKEQLAFRYLAGQNGAYPVVFSACQLASGDRNLMMKAFNTLSAILDGQPDLLDSAGQDLLLQTLKEYKEDAEMTLAGIRCIRHACLKHEQNRQDFVKGGVLPLLTGAIVLHGDSADVVRTASSALRIMTFDDDIRVPFGHAHDHAKMIVLENDGLRVLIEAAKAFTDNCSVLSELCATLSRLSVRNEFCQEIVDLGGLNFMVSLLADSIDHPDVVKQVLSAIRAIAGNDDVKDAIVTAGGTDLIVLAISHHLNNPQICEQGCAALCMLALRKPENCNVIMEGGGALAALQAMKAHPREVAVQKQACMLIRNLVSRSRDYSQPILEMGAEDLITEARATHKDCDDVAKAALRDLGCKVELRELWTGQKGSLAQ", "length": 448, "header": "tr|A0A8V1AFC6-1|A0A8V1AFC6_CHICK Computationally mapped isoform of Armadillo repeat containing 6 OS=Gallus gallus OX=9031 GN=ARMC6 PE=1 SV=1 CANONICAL=A0A8V1AHQ0-1" }, "locus": { "chromosome": "28", "start_pos": 4106689, "end_pos": 4102816, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068210.1", "url": "https://www.ensembl.org/id/ENSGALT00010068210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041953.1", "url": "https://www.ensembl.org/id/ENSGALP00010041953.1" } ] } 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Cilia and flagella associated protein 77 OS=Gallus gallus OX=9031 GN=CFAP77 PE=4 SV=1 CANONICAL=A0A8V1AHQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHQ7/entry#A0A8V1AA91-1", "sequence": { "sequence": "MAGPPRRPLSLAEVAAGSENERLGVARDSMLRNPRILKAELGKPLRNCYTLPGLDFSYGLYIERTDGGVPEAIGHWNTIKPRTNPTQNMPRDFITMNRGALKAGYTTARQFNLYYKAKDVRRKDDEYSRFKRSPPHVSPDRTYGIPARLGLISVLFQTVMLVRRHSVPPIEKCLGEAVPSPGQPYSELRSGPQPAWSPASAIDIGFLRI", "length": 209, "header": "tr|A0A8V1AA91-1|A0A8V1AA91_CHICK Computationally mapped isoform of Cilia and flagella associated protein 77 OS=Gallus gallus OX=9031 GN=CFAP77 PE=4 SV=1 CANONICAL=A0A8V1AHQ7-1" }, "locus": { "chromosome": "17", "start_pos": 7186818, "end_pos": 7134471, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069631.1", "url": "https://www.ensembl.org/id/ENSGALT00010069631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042892.1", "url": 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"isoform_ac": "F1NLZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHQ7/entry#F1NLZ5-1", "sequence": { "sequence": "MAGPPRRPLSLAEVAAGSENERLGVARDSMLRNPRILKAELGKPLRNCYTLPGLDFSYGLYIERTDGGVPEAIGHWNTIKPRTNPTQNMPRDFITMNRGALKAGYTTARQFNLYYKAKDVRRKDDEYSRFKRSPPHVSPDRTYGIPARPSTPLFDLLQHKYRELWMQQQRALTAALRLEKTKSQKDKVRDTRTTLLRKNPVPPKEESFWHLPHLEKVGPHLSTFPDRDARKKAFSASH", "length": 238, "header": "tr|F1NLZ5-1|F1NLZ5_CHICK Computationally mapped isoform of Cilia and flagella associated protein 77 OS=Gallus gallus OX=9031 GN=CFAP77 PE=4 SV=5 CANONICAL=A0A8V1AHQ7-1" }, "locus": { "chromosome": "17", "start_pos": 7186700, "end_pos": 7134471, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069632.1", "url": "https://www.ensembl.org/id/ENSGALT00010069632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042893.1", "url": "https://www.ensembl.org/id/ENSGALP00010042893.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417168", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417168", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A087WRI3-1", "protein_name": "Cilia- and flagella-associated protein 77", "gene_name": "Cfap77", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPDPAKPGKDLTAWKKKKQPVHRTVSQICPPPRRPLTVVDIRTGMENERLGVVRDSMFQNPLIVKAELGKPRERSCSLPGINFNYGLYIRGLDGGVPEAIGHWNVFKQQPTCPHELTRNYIAMNRGAVKAGLVTARENMLYRELNDIRINDQEDRRQKEPPPIPPNMTFGIRSRPSTPFFDLLQHRYQQLWVQEQKATQQAIKMEKKQKVILGKLYETRSSQLRKYKPPVKLDALWHMPHFKKVASHLATFPTEADRQRALKAHKEEYAVRQGTLRMGNYTHP", "length": 283 }, "evidence": [ { "id": "A0A8V1AHQ7", "url": "https://omabrowser.org/oma/group/A0A8V1AHQ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3Q1LJD6-1", "protein_name": "Cilia and flagella associated protein 77", "gene_name": "CFAP77", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPEARNSCQDLTRWKKKKPPVRRTVSQICPPPRRPLTVADIRPGMENERLGVVRDSMFQNPLIVKAELGKPRERSCSLPGINFNYGLYIRGLDGGVPEAIGHWNVFKQQPTCPHELTRNYIAMNRGAVKAGLVTARENLHYRQLNDIRISDQDDRRLKKEPPSLPPNMTFGIRARPSTPFFDLLQHRYQQLWVQEQKDTQKAIKLEKKHKVILGKLYETRSSQLRKYKPPMGLDTLWHMPHFQKVGPHLATFPTEADRQRAFKAHREECAVRQGTLRMGNYTHP", "length": 284 }, "evidence": [ { "id": "A0A8V1AHQ7", "url": "https://omabrowser.org/oma/group/A0A8V1AHQ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2BFC9-1", "protein_name": "Cilia- and flagella-associated protein 77", "gene_name": "cfap77", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESPRIGVVRDSMLHRPLLIKPTLGKSKSRGLSYPGPEFVFGTATTVQDGGVQEAISNWHTHTMSTTHRAAERDFIALNREGVKSGLVTAKELHQYRATHDIRRKPLTREGFRRSAPPRLSPDDSFFVSNRPSTPISELIEYKYAQRWLEEQQVRDRVLQAHQHKKAQLGRIQDTRTTLLRKSQPLPEAPSTWKLPRFQKVGAALDTFRDPEARKKAMNAHCSESVSRRGILGQGTYTVD", "length": 240 }, "evidence": [ { "id": "A0A8V1AHQ7", "url": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AHR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFGAGWYTGPCSNPCTVQCPQPLATSCNEPCVVSCPASRVIIFPPPVVVTFPGPILTTCPQETVVGSSAVPDGCASASLASVGAEVLCSEPSAERSIPTPMSQCTPQCSYAFASHWVHPCNRASYTCYQPPENEKEEHIPEKEKPETENIDTTNEDKETPEV", "length": 163, "header": "tr|A0A8V1AHR0-1|A0A8V1AHR0_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AHR0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR0/entry#A0A8V1AHR0-1", "sequence": { "sequence": "MSFGAGWYTGPCSNPCTVQCPQPLATSCNEPCVVSCPASRVIIFPPPVVVTFPGPILTTCPQETVVGSSAVPDGCASASLASVGAEVLCSEPSAERSIPTPMSQCTPQCSYAFASHWVHPCNRASYTCYQPPENEKEEHIPEKEKPETENIDTTNEDKETPEV", "length": 163, "header": "tr|A0A8V1AHR0-1|A0A8V1AHR0_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1AHR0-1" }, "locus": { "chromosome": "25", "start_pos": 1348526, "end_pos": 1348038, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067306.1", "url": "https://www.ensembl.org/id/ENSGALT00010067306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041185.1", "url": "https://www.ensembl.org/id/ENSGALP00010041185.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHR8-1", "uniprot_ac": "A0A8V1AHR8", "uniprot_id": "A0A8V1AHR8_CHICK", "mass": { "chemical_mass": 27429.0, "monoisotopic_mass": 27429.0 }, "refseq": { "ac": "XP_015135022", "name": "sperm acrosome-associated protein 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135022" }, "gene_names": [ { "name": "SPACA9", "type": "recommended", "evidence": [ { "id": "A0A8V1AHR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ] }, { "name": "C17H9ORF9", "type": "synonym", "evidence": [ { "id": "XP_015135022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135022" } ] }, { "name": "C9ORF9", "type": "synonym", "evidence": [ { "id": "XP_015135022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135022" } ] }, { "name": "SPACA9", "type": "synonym", "evidence": [ { "id": "XP_015135022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135022" } ] } ], "protein_names": [ { "name": "Sperm acrosome associated 9", "type": "synonym", "evidence": [ { "id": "A0A8V1AHR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8/entry#names_and_taxonomy" } ] }, { "name": "sperm acrosome-associated protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135022.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135022" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPACA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8", "locus": { "chromosome": "17", "start_pos": 7328550, "end_pos": 7321737, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028806", "url": "https://www.ensembl.org/id/ENSGALG00010028806" } ] } } ], "crossref": [ { "id": "A0A8V1AHR8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003509", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003509", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "772069", "url": "https://www.ncbi.nlm.nih.gov/gene/772069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772069", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EHHCYNS", "url": "https://omabrowser.org/oma/group/EHHCYNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHR8", "url": "https://www.orthodb.org/?gene=A0A8V1AHR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZQ8", "url": "https://www.orthodb.org/?gene=E1BZQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32455:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32455:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15120", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15120", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZQ8", "url": "https://www.uniprot.org/uniprotkb/E1BZQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZQ8-1", "url": "https://www.uniprot.org/uniprotkb/E1BZQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEVKDTLKVIEDNYKLFLQQQFTFVGALQHTRENAHDMIRPVASISQVQSYMDHHCNNLTDRRILTMFLNICNDLSNLCHKLETLHPGNSTTNEILERCKLLLNHSNDLSTIRAKYPHDVVNHLSCDEAKNHFGGVVSLIPIVLDGVKEWLSHTEKLPRRMLCNVSGGSAVTEKRAPQDAAARAAISPKIPSVHPEAQTSVSNKDCIQVQGNKHVRKKHETDRENQNGKLKGPWKPPGRHAF", "length": 243, "header": "tr|A0A8V1AHR8-1|A0A8V1AHR8_CHICK Isoform 1 of Sperm acrosome associated 9 OS=Gallus gallus OX=9031 GN=SPACA9 PE=1 SV=1 CANONICAL=A0A8V1AHR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8/entry#A0A8V1AHR8-1", "sequence": { "sequence": "MNEVKDTLKVIEDNYKLFLQQQFTFVGALQHTRENAHDMIRPVASISQVQSYMDHHCNNLTDRRILTMFLNICNDLSNLCHKLETLHPGNSTTNEILERCKLLLNHSNDLSTIRAKYPHDVVNHLSCDEAKNHFGGVVSLIPIVLDGVKEWLSHTEKLPRRMLCNVSGGSAVTEKRAPQDAAARAAISPKIPSVHPEAQTSVSNKDCIQVQGNKHVRKKHETDRENQNGKLKGPWKPPGRHAF", "length": 243, "header": "tr|A0A8V1AHR8-1|A0A8V1AHR8_CHICK Isoform 1 of Sperm acrosome associated 9 OS=Gallus gallus OX=9031 GN=SPACA9 PE=1 SV=1 CANONICAL=A0A8V1AHR8-1" }, "locus": { "chromosome": "17", "start_pos": 7325965, "end_pos": 7322382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069679.1", "url": "https://www.ensembl.org/id/ENSGALT00010069679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042906.1", "url": "https://www.ensembl.org/id/ENSGALP00010042906.1" } ] } }, { "isoform_ac": "E1BZQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8/entry#E1BZQ8-1", "sequence": { "sequence": "MNEVKDTLKVIEDNYKLFLQQQFTFVGALQHTRENAHDMIRPVASISQVQSYMDHHCNNLTDRRILTMFLNICNDLSNLCHKLETLHPGNSTTNEILERCKLLLNHSNDLSTIRAKYPHDVVNHLSCDEAKNHFGGVVSLIPIVLDGVKEWLSHTEKLPRRMLCNAN", "length": 167, "header": "tr|E1BZQ8-1|E1BZQ8_CHICK Computationally mapped isoform of Sperm acrosome associated 9 OS=Gallus gallus OX=9031 GN=SPACA9 PE=1 SV=3 CANONICAL=A0A8V1AHR8-1" }, "locus": { "chromosome": "17", "start_pos": 7326950, "end_pos": 7322382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069681.1", "url": "https://www.ensembl.org/id/ENSGALT00010069681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042907.1", "url": "https://www.ensembl.org/id/ENSGALP00010042907.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772069", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F6S0F4-1", "protein_name": "Sperm acrosome associated 9", "gene_name": "SPACA9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMNEVKESLRSVEQKYKIFQQQQFTFIGALEHCRENAHDKIRPISSIGQVQSYMEHHCSNSTDRRILLMFLDICSELSKLCQHFEALHAGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPIILDLMKEWVAHSEKLPRKALQQVSEPQAATRATAHAPQASGTQPQLRKQNCGQLIQNIPKPGGKDQGSSKPPWRPPGGKL", "length": 224 }, "evidence": [ { "id": "A0A8V1AHR8", "url": "https://omabrowser.org/oma/group/A0A8V1AHR8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TPM5-1", "protein_name": "Sperm acrosome-associated protein 9", "gene_name": "Spaca9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNEVKESLRSIEQKYKLFQQQQFTFIAALEHCRENAHDKIRPISSIEQVQSYMEHYCNNSTHRRILIMFMDICSELSKLCQHFEALHSGTPVTNSLLEKCKTLVSQSNDLSSLRAKYPHEVVNHLSCDEARNHYGGVVSLIPIVLDFMKEWIAHSEKLPRKVLQHGTT", "length": 168 }, "evidence": [ { "id": "A0A8V1AHR8", "url": "https://omabrowser.org/oma/group/A0A8V1AHR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96E40-1", "protein_name": "Sperm acrosome-associated protein 9", "gene_name": "SPACA9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRKVLQHVSEPQAHQESTRGAARPAQAIGTQPRATKHKCRQLTKASLKPRGCSKPPWRPPGGKL", "length": 222 }, "evidence": [ { "id": "A0A8V1AHR8", "url": "https://omabrowser.org/oma/group/A0A8V1AHR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "axonemal microtubule doublet inner sheath", "id": "GO:0160110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJL9-1", "uniprot_ac": "A0A8V1AJL9", "uniprot_id": "A0A8V1AJL9_CHICK", "mass": { "chemical_mass": 70493.0, "monoisotopic_mass": 70493.0 }, "refseq": {}, "gene_names": [ { "name": "CARD9", "type": "recommended", "evidence": [ { "id": "A0A8V1AJL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ] } ], "protein_names": [ { "name": "Caspase recruitment domain family member 9", "type": "synonym", "evidence": [ { "id": "A0A8V1AJL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CARD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9", "locus": { "chromosome": "17", "start_pos": 8523380, "end_pos": 8515532, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028162", "url": "https://www.ensembl.org/id/ENSGALG00010028162" } ] } } ], "crossref": [ { "id": "A0A8V1AJL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08809", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08809", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427756", "url": "https://www.ncbi.nlm.nih.gov/gene/427756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HEVDWEN", "url": "https://omabrowser.org/oma/group/HEVDWEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7Q2", "url": "https://www.orthodb.org/?gene=A0A8V1A7Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFF2", "url": "https://www.orthodb.org/?gene=A0A8V1AFF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHS1", "url": "https://www.orthodb.org/?gene=A0A8V1AHS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJL9", "url": "https://www.orthodb.org/?gene=A0A8V1AJL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14559:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14559:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5607764", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5607764", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSDQEKRSEGFCLHKPRKDEAAHCYFSLTTMLEEDNDETCWNSLENFRVKLISVIDPSRITPYLRQCQVINHDDEEQVLNDPSLVMRKRKAGVLLDILQRTGRKGFEAFMESLELYYPQLYKKITGKEPSRVFSLIIDTAGESGLSQLLMNEITKLQRTVQEERQKAQELTVWLHTKENMIREMWVRDSLLRKHQERVQKMREERDSLSKELRKCKDENYNLAMSYARQSEEKSSALMKNRDLLLEIDSLKHSLMKAEDDCKLERKHSMKLKHAIEQRPSHEVMWEIQQEKELLLAKNQELENTLQVAREQNLETSLSHETVQNDCSQVLERQDLLNTLYHLRKELRQAEVLRDKYAEEKEILELQCTSLRKDSQMYKKRMEAVLEQMEEVASERDQALLTREQFYTQYSKNLVERDTYRKQIRELGERCDELQLQLFQKEGQLLATEAKLKRLQLELPALTSDLDDTSSRDSQDLTLHGHLDEDSHLTKKDCCKGQTQQFSMQESNLTAESPTFEECSSAHEELSEKERRRMKDCFERYRRSGRIPPPPPPSRAPFPSGSVSRIPVSRKRALRRAPAGRRPEADWEPSTGSDNTDTEGS", "length": 601, "header": "tr|A0A8V1AJL9-1|A0A8V1AJL9_CHICK Isoform 1 of Caspase recruitment domain family member 9 OS=Gallus gallus OX=9031 GN=CARD9 PE=4 SV=1 CANONICAL=A0A8V1AJL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9/entry#A0A8V1A7Q2-1", "sequence": { "sequence": "MCSDQEKRSEGFCLHKPRKDEAAHCYFSLTTMLEEDNDETCWNSLENFRVKLISVIDPSRITPYLRQCQVINHDDEEQVLNDPSLVMRKRKAGVLLDILQRTGRKGFEAFMESLELYYPQLYKKITGKEPSRVFSLIIDTAGESGLSQLLMNEITKLQRTVQEERQKAQELTVWLHTKENMIREMWVRDSLLRKHQERVQKMREERDSLSKELRKCKDENYNLAMSYARQSEEKSSALMKNRDLLLEIDSLKHSLMKAEDDCKLERKHSMKLKHAIEQRPSHEVMWEIQQEKELLLAKNQELENTLQQVAREQNLETSLSHETVQNDCSQVLERQDLLNTLYHLRKELRQAEVLRDKYAEEKEILELQCTSLRKDSQMYKKRMEAVLEQMEEVASERDQALLTREQFYTQYSKNLVERDTYRKQIRELGERCDELQLQLFQKEGQLLATEAKLKRLQLELPALTSDLDDTSSRDSQDLTLHGHLDEDSHLTKKDCCKGQTQQFSMQESNLTAESPTFEECSSAHEELSEKERRRMKDCFERYRRKRALRRAPAGRRPEADWEPSTGSDNTDTEGS", "length": 575, "header": "tr|A0A8V1A7Q2-1|A0A8V1A7Q2_CHICK Computationally mapped isoform of Caspase recruitment domain family member 9 OS=Gallus gallus OX=9031 GN=CARD9 PE=4 SV=1 CANONICAL=A0A8V1AJL9-1" }, "locus": { "chromosome": "17", "start_pos": 8523313, "end_pos": 8515958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068237.1", "url": "https://www.ensembl.org/id/ENSGALT00010068237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041980.1", "url": "https://www.ensembl.org/id/ENSGALP00010041980.1" } ] } }, { "isoform_ac": "A0A8V1AFF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9/entry#A0A8V1AFF2-1", "sequence": { "sequence": "MCSDQEKRSEGFCLHKPRKDEAAHCYFSLTTMLEEDNDETCWNSLENFRVKLISVIDPSRITPYLRQCQVINHDDEEQVLNDPSLVMRKRKAGVLLDILQRTGRKGFEAFMESLELYYPQLYKKITGKEPSRVFSLIIDTAGESGLSQLLMNEITKLQRTVQEERQKAQELTVWLHTKENMIREMWVRDSLLRKHQERVQKMREERDSLSKELRKCKDENYNLAMSYARQSEEKSSALMKNRDLLLEIDSLKHSLMKAEDDCKLERKHSMKLKHAIEQRPSHEVMWEIQQEKELLLAKNQELENTLQVAREQNLETSLSHETVQNDCSQVLERQDLLNTLYHLRKELRQAEVLRDKYAEEKEILELQCTSLRKDSQMYKKRMEAVLEQMEEVASERDQALLTREQFYTQYSKNLVERDTYRKQIRELGERCDELQLQLFQKEGQLLATEAKLKRLQLELPALTSDLDDTSSRDSQDLTLHGHLDEDSHLTKSKAFIGENIQYSSCPVFRGTGTDVLFILVQKRCID", "length": 526, "header": "tr|A0A8V1AFF2-1|A0A8V1AFF2_CHICK Computationally mapped isoform of Caspase recruitment domain family member 9 OS=Gallus gallus OX=9031 GN=CARD9 PE=4 SV=1 CANONICAL=A0A8V1AJL9-1" }, "locus": { "chromosome": "17", "start_pos": 8521093, "end_pos": 8515958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068236.1", "url": "https://www.ensembl.org/id/ENSGALT00010068236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041979.1", "url": "https://www.ensembl.org/id/ENSGALP00010041979.1" } ] } }, { "isoform_ac": "A0A8V1AHS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9/entry#A0A8V1AHS1-1", "sequence": { "sequence": "MCSDQEKRSEGFCLHKPRKDEAAHCYFSLTTMLEEDNDETCWNSLENFRVKLISVIDPSRITPYLRQCQVINHDDEEQVLNDPSLVMRKRKAGVLLDILQRTGRKGFEAFMESLELYYPQLYKKITGKEPSRVFSLIIDTAGESGLSQLLMNEITKLQRTVQEERQKAQELTVWLHTKENMIREMWVRDSLLRKHQERVQKMREERDSLSKELRKCKDENYNLAMSYARQSEEKSSALMKNRDLLLEIDSLKHSLMKAEDDCKLERKHSMKLKHAIEQRPSHEVMWEIQQEKELLLAKNQELENTLQVAREQNLETSLSHETVQNDCSQVLERQDLLNTLYHLRKELRQAEVLRDKYAEEKEILELQCTSLRKDSQMYKKRMEAVLEQMEEVASERDQALLTREQFYTQYSKNLVERDTYRKQIRELGERCDELQLQLFQKEGQLLATEAKLKRLQLELPALLTLHGHLDEDSHLTKKDCCKGQTQQFSMQESNLTAESPTFEECSSAHEELSEKERRRMKDCFERYRRKRALRRAPAGRRPEADWEPSTGSDNTDTEGS", "length": 560, "header": "tr|A0A8V1AHS1-1|A0A8V1AJL9_CHICK Computationally mapped isoform of Caspase recruitment domain family member 9 OS=Gallus gallus OX=9031 GN=CARD9 PE=4 SV=1 CANONICAL=A0A8V1AJL9-1" }, "locus": { "chromosome": "17", "start_pos": 8523313, "end_pos": 8515958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068235.1", "url": "https://www.ensembl.org/id/ENSGALT00010068235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041978.1", "url": "https://www.ensembl.org/id/ENSGALP00010041978.1" } ] } }, { "isoform_ac": "A0A8V1AJL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9/entry#A0A8V1AJL9-1", "sequence": { "sequence": "MCSDQEKRSEGFCLHKPRKDEAAHCYFSLTTMLEEDNDETCWNSLENFRVKLISVIDPSRITPYLRQCQVINHDDEEQVLNDPSLVMRKRKAGVLLDILQRTGRKGFEAFMESLELYYPQLYKKITGKEPSRVFSLIIDTAGESGLSQLLMNEITKLQRTVQEERQKAQELTVWLHTKENMIREMWVRDSLLRKHQERVQKMREERDSLSKELRKCKDENYNLAMSYARQSEEKSSALMKNRDLLLEIDSLKHSLMKAEDDCKLERKHSMKLKHAIEQRPSHEVMWEIQQEKELLLAKNQELENTLQVAREQNLETSLSHETVQNDCSQVLERQDLLNTLYHLRKELRQAEVLRDKYAEEKEILELQCTSLRKDSQMYKKRMEAVLEQMEEVASERDQALLTREQFYTQYSKNLVERDTYRKQIRELGERCDELQLQLFQKEGQLLATEAKLKRLQLELPALTSDLDDTSSRDSQDLTLHGHLDEDSHLTKKDCCKGQTQQFSMQESNLTAESPTFEECSSAHEELSEKERRRMKDCFERYRRSGRIPPPPPPSRAPFPSGSVSRIPVSRKRALRRAPAGRRPEADWEPSTGSDNTDTEGS", "length": 601, "header": "tr|A0A8V1AJL9-1|A0A8V1AJL9_CHICK Isoform 1 of Caspase recruitment domain family member 9 OS=Gallus gallus OX=9031 GN=CARD9 PE=4 SV=1 CANONICAL=A0A8V1AJL9-1" }, "locus": { "chromosome": "17", "start_pos": 8523313, "end_pos": 8515958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068238.1", "url": "https://www.ensembl.org/id/ENSGALT00010068238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041981.1", "url": "https://www.ensembl.org/id/ENSGALP00010041981.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5607764", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5607764", "resource": "Reactome", "description": "CLEC7A (Dectin-1) signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TP44-1", "protein_name": "Caspase recruitment domain family member 9", "gene_name": "CARD9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"sequence": { "sequence": "MSDYENDDECWSALESFRVKLISVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRKVGVLLDILQRTGHKGYVAFLESLELYYPQLYRKVTGKEPARVFSMIIDASGESGLTQLLMTEVMKLQKKVQDLTALLSSKDDFIKELRVKDSLLRKHQERVQRLKEECELSSAELKRCKDENYDLAMRLAHLSEEKGAALMRNRDLQLEVDQLRHSLMKAEDDCKVERKHTLKLRHAMEQRPSQELLWDLQQERDLLQARVQELEVSVQEGKLHRNSPYIQVLEEDWRQALQEHQEQASTIFSLRKDLRQAEALRTRCMEEKEMFELQCLALRKDAKMYKDRIEAILQQMEEVSIERDQAMTSREELHAQCAQSFQDKDKLRKQVRELDEKADELQLQLFQTESRLLAAEGRLKQQQLDMLILSSDLEDSSPRNSQELSLPQDLEEDAQLSDKGVLADRESPEQPFVVLNKKHLSQTHDTVPSSSEPPEKERRRLKESFENYRRKRALRKMQNSWRQGEGDHGNTTGSDNTDTEGS", "length": 536 }, "evidence": [ { "id": "A0A8V1AJL9", "url": "https://omabrowser.org/oma/group/A0A8V1AJL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H257-1", "protein_name": "Caspase recruitment domain-containing protein 9", "gene_name": "CARD9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "positive regulation of interleukin-17 production", "id": "GO:0032740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "neutrophil mediated immunity", "id": "GO:0002446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "positive regulation of chemokine production", "id": "GO:0032722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "positive regulation of interleukin-6 production", "id": "GO:0032755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL9" } ], "pmid": "" }, { "name": "apoptotic signaling pathway", "id": "GO:0097190", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5", "locus": {} } ], "crossref": [ { "id": "A0A8V1AHS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395366", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MQSDNFC", "url": "https://omabrowser.org/oma/group/MQSDNFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7Q7", "url": "https://www.orthodb.org/?gene=A0A8V1A7Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFG2", "url": "https://www.orthodb.org/?gene=A0A8V1AFG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHS5", "url": "https://www.orthodb.org/?gene=A0A8V1AHS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHS9", "url": "https://www.orthodb.org/?gene=A0A8V1AHS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9953170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9953170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9968551", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9968551", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTPVLPMPAPLCLVTNKDGVLALNPAALAVLHSVTQPVVVVAIAGLYRTGKSFLMNQLAQKRTGEQRGKPHPFWVTFCGISDSSLSKGFPLGPTVYAETKGIWMWCLPHPRQPRVTLVLLDTEGLGDPNKDDDHSDAWIFTLALLLSSTLVYNSIGTIDQRALEQLRLVTELSEHIRVREKDNNPASNFVSIFPGFVWTVRDFTLQLRAGEKTLSEDEYLEDVLRLQTGGGQKAQERNELRRCLRNFFPRRKLFTMERPAADANLTRLEELREDELQPGFRKQVDAFCRYIWEEAPVKVLPGGHQVTGSALACLAEKYVAAISSGSVPCVESAVTALARAENSAAVQAAVAEYQQGMEHDLVLPTASYDALLAVHRDCEQRALALFLSRAFADHEHQYHDELVHKLEAAKEEFCQRNKEASEQRCRTVLQELWRDVELRLQRGDYVARGGAQLFKDDLHRVLEEYKQRPDKGVRVSEVWGSGVGWHRVRWNCASWLYGQAEAVLKEFLREHEGLAQVLKATEVQLELAERQQEAAAAEAEAARKAAEAWREEQQRSMEEHKRQLEQWMKEEQRTWLEEQQRVLEHHRKEYEALLREGFTREAAALKEQIRELQEMMRPPKCTVL", "length": 625, "header": "tr|A0A8V1AHS5-1|A0A8V1AHS5_CHICK Isoform 1 of Guanylate binding protein OS=Gallus gallus OX=9031 GN=LOC121106626 PE=1 SV=1 CANONICAL=A0A8V1AHS5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5/entry#A0A8V1A7Q7-1", "sequence": { "sequence": "MDTPVLPMPAPLCLVTNKDGVLALNPAALAVLHSVTQPVVVVAIAGLYRTGKSFLMNQLAQKRTGFPLGPTVYAETKGIWMWCLPHPHRPGVTLVLLDTEGLGDPSKVSARVGGPRQPIEAELPVTPICVQDDNHSDAWIFTLALLLSSTLVYNSVGTIDQRALEQLRLVTELSEHIRVREKDDNPAFNFVGIFPGFVWTVRDFMLQLRAGEKTLSEDEYLEDVMRLQTGGGQKAQERNELRRCLRNFFPRRKLFTMERPAADADLTRLEELREDELQPGFRKQVDAFCRYIWEEAPVKVLPGGHQVTGSALAYLTEKYVAAISSGSVPCVESAVKALARAENTAAVQAAVAEYQRGMEQDLVLPTASYDALLAVHRDCEQRAITLFLSRAFADHEHQYHDKLVDKLEMAKEEFCQRNKEASEQRCRTVLQELWRDVELRLQRGDYVARGGAQLFKDDLNRVLEEYKQRHDKGVRAEAVLKEFLREHEGLAQVLKATEVQLELAERQQEAAAAEAEAARKAAEAWREEQQRSMEEHKRQLEQWMKEEQRTWLEEQQRVLEHHRKEYEALLREGFTREAAALKEQIRELQEMMRPPKCTVL", "length": 600, "header": "tr|A0A8V1A7Q7-1|A0A8V1A7Q7_CHICK Computationally mapped isoform of Guanylate binding protein OS=Gallus gallus OX=9031 GN=LOC121106626 PE=1 SV=1 CANONICAL=A0A8V1AHS5-1" }, "locus": { "chromosome": "12", "start_pos": 2438965, "end_pos": 2424561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068242.1", "url": "https://www.ensembl.org/id/ENSGALT00010068242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041985.1", "url": "https://www.ensembl.org/id/ENSGALP00010041985.1" } ] } }, { "isoform_ac": "A0A8V1AFG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5/entry#A0A8V1AFG2-1", "sequence": { "sequence": "MDTPVLPMPAPLCLVTNKDGVLALNPAALAVLHSVTQPVVVVAIAGLYRTGKSFLMNQLAQKRTGFPLGPTVYAETKGIWMWCLPHPRQPRVTLVLLDTEGLGDPNKDDDHSDAWIFTLALLLSSTLVYNSIGTIDQRALEQLRLVTELSEHIRVREKDNNPASNFVSIFPGFVWTVRDFTLQLRAGEKTLSEDEYLEDVLRLQTGGGQKAQERNELRRCLRNFFPRRKLFTMERPAADANLTRLEELREDELQPGFRKQVDAFCRYIWEEAPVKVLPGGHQVTGSALAYLTEKYVAAISSGSVPCVESAVKALARAENTAAVQAAVAEYQRGMEQDLVLPTASYDALLAVHRDCEQRAITLFLSRAFADHEHQYHDKLVDKLEMAKEEFCQRNKEASEQRCRTVLQELWRDVELRLQRGDYVARGGAQLFKDDLNRVLEEYKQRHDKGVRAEAVLKEFLREHEGLAQVLKATEVQLELAERQQEAAAAEAEAARKAAEAWREEQQRSMEEHKRQLEQWMKEEQRTWLEEQQRVLEHHRKEYEALLREGFRLEAAAKEKQIRELQEEMRSCNCTVL", "length": 576, "header": "tr|A0A8V1AFG2-1|A0A8V1AFG2_CHICK Computationally mapped isoform of Guanylate binding protein OS=Gallus gallus OX=9031 GN=LOC121106626 PE=3 SV=1 CANONICAL=A0A8V1AHS5-1" }, "locus": { "chromosome": "12", "start_pos": 2438965, "end_pos": 2413071, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068246.1", "url": "https://www.ensembl.org/id/ENSGALT00010068246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041989.1", "url": "https://www.ensembl.org/id/ENSGALP00010041989.1" } ] } }, { "isoform_ac": "A0A8V1AHS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5/entry#A0A8V1AHS5-1", "sequence": { "sequence": "MDTPVLPMPAPLCLVTNKDGVLALNPAALAVLHSVTQPVVVVAIAGLYRTGKSFLMNQLAQKRTGEQRGKPHPFWVTFCGISDSSLSKGFPLGPTVYAETKGIWMWCLPHPRQPRVTLVLLDTEGLGDPNKDDDHSDAWIFTLALLLSSTLVYNSIGTIDQRALEQLRLVTELSEHIRVREKDNNPASNFVSIFPGFVWTVRDFTLQLRAGEKTLSEDEYLEDVLRLQTGGGQKAQERNELRRCLRNFFPRRKLFTMERPAADANLTRLEELREDELQPGFRKQVDAFCRYIWEEAPVKVLPGGHQVTGSALACLAEKYVAAISSGSVPCVESAVTALARAENSAAVQAAVAEYQQGMEHDLVLPTASYDALLAVHRDCEQRALALFLSRAFADHEHQYHDELVHKLEAAKEEFCQRNKEASEQRCRTVLQELWRDVELRLQRGDYVARGGAQLFKDDLHRVLEEYKQRPDKGVRVSEVWGSGVGWHRVRWNCASWLYGQAEAVLKEFLREHEGLAQVLKATEVQLELAERQQEAAAAEAEAARKAAEAWREEQQRSMEEHKRQLEQWMKEEQRTWLEEQQRVLEHHRKEYEALLREGFTREAAALKEQIRELQEMMRPPKCTVL", "length": 625, "header": "tr|A0A8V1AHS5-1|A0A8V1AHS5_CHICK Isoform 1 of Guanylate binding protein OS=Gallus gallus OX=9031 GN=LOC121106626 PE=1 SV=1 CANONICAL=A0A8V1AHS5-1" }, "locus": { "chromosome": "12", "start_pos": 2438965, "end_pos": 2424561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068240.1", "url": "https://www.ensembl.org/id/ENSGALT00010068240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041983.1", "url": "https://www.ensembl.org/id/ENSGALP00010041983.1" } ] } }, { "isoform_ac": "A0A8V1AHS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5/entry#A0A8V1AHS9-1", "sequence": { "sequence": "MDTPVLPMPAPLCLVTNKDGVLALNPAALAVLHSVTQPVVVVAIAGLYRTGKSFLMNQLAQKRTGFPLGPTVYAETKGIWMWCLPHPRQPRVTLVLLDTEGLGDPNKDDDHSDAWIFTLALLLSSTLVYNSIGTIDQRALEQLRLVTELSEHIRVREKDNNPASNFVSIFPGFVWTVRDFTLQLRAGEKTLSEDEYLEDVLRLQTGGGQKAQERNELRRCLRNFFPRRKLFTMERPAADANLTRLEELREDELQPGFRKQVDAFCRYIWEEAPVKVLPGGHQVTGSALACLAEKYVAAISSGSVPCVESAVTALARAENSAAVQAAVAEYQQGMEHDLVLPTASYDALLAVHRDCEQRALALFLSRAFADHEHQYHDELVHKLEAAKEEFCQRNKEASEQRCRTVLQELWRDVELRLQRGDYVARGGAQLFKDDLHRVLEEYKQRPDKGVRAEAVLKEFLREHEGLAQVLKATEVQLELAERQQEAAAAEAEAARKAAEAWKEEQKRSMEEYERQLQQRMKEEQRTWLEEQQRVLEHHRKEYEALLREGFTREAAALKEQIRELQEMMRPPKCTVL", "length": 576, "header": "tr|A0A8V1AHS9-1|A0A8V1AHS9_CHICK Computationally mapped isoform of Guanylate binding protein OS=Gallus gallus OX=9031 GN=LOC121106626 PE=1 SV=1 CANONICAL=A0A8V1AHS5-1" }, "locus": { "chromosome": "12", "start_pos": 2438965, "end_pos": 2436583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068245.1", "url": "https://www.ensembl.org/id/ENSGALT00010068245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041988.1", "url": "https://www.ensembl.org/id/ENSGALP00010041988.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395366", "resource": "KEGG Pathway" }, { "id": "R-GGA-9953170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9953170", "resource": "Reactome", "description": "GBP-mediated host defense" }, { "id": "R-GGA-9968551", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9968551", "resource": "Reactome", "description": "Regulation of GBP-mediated host defense" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQL3-1", "protein_name": "Guanylate binding protein 4", "gene_name": "Gbp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAPICLVQNWKEQLTVNLEAIGILEQIAQPLVVVAIVGLYRTGKSYLMNRLAGRNHGFSLGSTVQSETKGIWMWCVPHPTKPTHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTQLIRAKSDPREDKVEDSSEFVGFFPDFIWAVRDFVLELKLDGRPITEDEYLENALKLIPENNPKGQKSNMTRECIRYFFPVRKCFVFDRPTNDKSLLFQIENVPENQLEWNFQVESENFCSYIFANGKTKTLRGGVIVTGNRLGTLVQTYVDAINSGTVPCLENAVTALAQRENSAAVQKAAEHYAEQMAQRLRLPTDTLQELLEVHSACEKEAIAVFMEHSFKDDEQEFQKRLVATIEKWKEEFMLRNEAASIRHCQAELEKLSESLKESISCGAFSVPGGHSLYLEARKKVELSYEQVPRKGVKAKEVLKSFLQSQATVENSILQSDKALTDGERAVAAERTKKEVAEKERELLKQRQKEQEQVMEAQERSFQENIAKLQEKMERERVMLLREQEKMMEHKLKVQKELLVEGFRKKSDMLKNEISQLREEIERTRKKPSLFAHILDTVGNAFIMILPGAGKICGAGMKVLSSLMK", "length": 620 }, "evidence": [ { "id": "A0A8V1AHS5", "url": "https://omabrowser.org/oma/group/A0A8V1AHS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61107-1", "protein_name": "Guanylate-binding protein 3", "gene_name": "Gbp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAPICLVENWKNQLTVNLEAIRILEQIAQPLVVVAIVGLYRTGKSYLMNRLAGRNHGFSLGSTVQSETKGIWMWCVPHPTKPTHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINQQALEQLHFVTELTQLIRAKSSPREDKVKDSSEFVGFFPDFIWAVRDFALELKLNGRPITEDEYLENALKLIQGDNLKVQQSNMTRECIRYFFPVRKCFVFDRPTSDKRLLLQIENVPENQLERNFQVESEKFCSYIFTNGKTKTLRGGVIVTGNRLGTLVQTYVNAINSGTVPCLENAVTTLAQRENSIAVQKAADHYSEQMAQRMRLPTDTLQELLTVHAACEKEAIAVFMEHSFKDDEQEFQKKLVVTIEERKEEFIRQNEAASIRHCQAELERLSESLRKSISCGAFSVPGGHSLYLEARKKIELGYQQVLRKGVKAKEVLKSFLQSQAIMEDSILQSDKALTDGERAIAAERTKKEVAEKELELLRQRQKEQEQVMEAQERSFRENIAKLQEKMESEKEMLLREQEKMLEHKLKVQEELLIEGFREKSDMLKNEISHLREEMERTRRKPSLFGQILDTIGNAFIMILPGAGKLFGVGLKFLGSLSS", "length": 620 }, "evidence": [ { "id": "A0A8V1AHS5", "url": "https://omabrowser.org/oma/group/A0A8V1AHS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PP9-1", "protein_name": "Guanylate-binding protein 4", "gene_name": "GBP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGERTLHAAVPTPGYPESESIMMAPICLVENQEEQLTVNSKALEILDKISQPVVVVAIVGLYRTGKSYLMNRLAGKRNGFPLGSTVQSETKGIWMWCVPHLSKPNHTLVLLDTEGLGDVEKSNPKNDSWIFALAVLLSSSFVYNSVSTINHQALEQLHYVTELAELIRAKSCPRPDEAEDSSEFASFFPDFIWTVRDFTLELKLDGNPITEDEYLENALKLIPGKNPKIQNSNMPRECIRHFFRKRKCFVFDRPTNDKQYLNHMDEVPEENLERHFLMQSDNFCSYIFTHAKTKTLREGIIVTGKRLGTLVVTYVDAINSGAVPCLENAVTALAQLENPAAVQRAADHYSQQMAQQLRLPTDTLQELLDVHAACEREAIAVFMEHSFKDENHEFQKKLVDTIEKKKGDFVLQNEEASAKYCQAELKRLSEHLTESILRGIFSVPGGHNLYLEEKKQVEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKEQELLREKQKEQQQMMEAQERSFQEYMAQMEKKLEEERENLLREHERLLKHKLKVQEEMLKEEFQKKSEQLNKEINQLKEKIESTKNEQLRLLKILDMASNIMIVTLPGASKLLGVGTKYLGSRI", "length": 640 }, "evidence": [ { "id": "A0A8V1AHS5", "url": "https://omabrowser.org/oma/group/A0A8V1AHS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS5" }, { "id": "PS51715", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51715" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GB1/RHD3-type G", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 297, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT7" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT7" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT7" } ], "pmid": "" }, { "name": "chaperone-mediated protein complex assembly", "id": "GO:0051131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT7" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT7" }, { "id": "PS51501", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNL-type", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 150, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHV9-1", "uniprot_ac": "A0A8V1AHV9", "uniprot_id": "A0A8V1AHV9_CHICK", "mass": { "chemical_mass": 55966.0, "monoisotopic_mass": 55966.0 }, "refseq": { "ac": "XP_423637", "name": "solute carrier family 2, facilitated glucose transporter member 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423637" }, "gene_names": [ { "name": "SLC2A6", "type": "recommended", "evidence": [ { "id": "A0A8V1AHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" } ] }, { "name": "SLC2A6", "type": "synonym", "evidence": [ { "id": "XP_423637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423637" } ] } ], "protein_names": [ { "name": "Solute carrier family 2, facilitated glucose transporter member 6", "type": "recommended", "evidence": [ { "id": "A0A8V1AHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9/entry#names_and_taxonomy" } ] }, { "name": "Glucose transporter type 6", "type": "synonym", "evidence": [ { "id": "A0A8V1AHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 2, facilitated glucose transporter member 6", "type": "synonym", "evidence": [ { "id": "XP_423637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423637" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_423637.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423637" } ] }, { "annotation": "Probable sugar transporter that acts as a regulator of glycolysis in macrophages. Does not transport glucose.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK38", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK38#function" }, { "database": "UniProtKB", "id": "ARBA00053035", "url": "https://www.uniprot.org/uniprotkb/ARBA00053035#function" }, { "database": "UniProtKB", "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC2A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9", "locus": { "chromosome": "17", "start_pos": 7543152, "end_pos": 7547412, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028872", "url": "https://www.ensembl.org/id/ENSGALG00010028872" } ] } } ], "crossref": [ { "id": "A0A8V1AHV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17434", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17434", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425954", "url": "https://www.ncbi.nlm.nih.gov/gene/425954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VTCVLVY", "url": "https://omabrowser.org/oma/group/VTCVLVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHV9", "url": "https://www.orthodb.org/?gene=A0A8V1AHV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK38", "url": "https://www.orthodb.org/?gene=A0A8V1AK38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48021:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48021:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_423637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK38", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPSVREPLVRRSSSSYHTFPESIRRGLDKEYLQSLNNKRLYMAVFAAVLGNFSFGFALVYPSPVIPALETHPNPALRLDRYRASWFGSVFMLGAAAGGLSTMLLNDHLGRKLSIMFSAVPSAVGYALMASAQGIEMLLLGRVLTGYAGGVTSASIPVYISEISHPGVRGMLGTCPQIMAVLGSLILYVLGLLLDWRWLAVAGEVPVLTMILLLCFMPNSPRFLLSQGKEDEALRSLCWLRGKDTDYAQEYEQIKDSVRKQSQRISCAEIKDPFIYKPILIAVGMRFLQQLSGVTCVLVYLQPIFKKTAVILKPEYDAALVGLVRLFSVAIAAVSMDKAGRKILLFVSAGVMLASNLTMGLYIHLVPSSQNSTIANRTLGSLASPAEPTNYITLIPLLAAMFFIMGYAMGWGPITWLLMSEILPLKARGVASGLCVVVSWLTAFALTQLFLGVVEFFGLEVPFLFFAVICAGNVLFTACCVPETKRRSLEQIEAFFRTGRKSFLRSFRR", "length": 509, "header": "tr|A0A8V1AHV9-1|A0A8V1AHV9_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 6 OS=Gallus gallus OX=9031 GN=SLC2A6 PE=1 SV=1 CANONICAL=A0A8V1AHV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9/entry#A0A8V1AHV9-1", "sequence": { "sequence": "MEPSVREPLVRRSSSSYHTFPESIRRGLDKEYLQSLNNKRLYMAVFAAVLGNFSFGFALVYPSPVIPALETHPNPALRLDRYRASWFGSVFMLGAAAGGLSTMLLNDHLGRKLSIMFSAVPSAVGYALMASAQGIEMLLLGRVLTGYAGGVTSASIPVYISEISHPGVRGMLGTCPQIMAVLGSLILYVLGLLLDWRWLAVAGEVPVLTMILLLCFMPNSPRFLLSQGKEDEALRSLCWLRGKDTDYAQEYEQIKDSVRKQSQRISCAEIKDPFIYKPILIAVGMRFLQQLSGVTCVLVYLQPIFKKTAVILKPEYDAALVGLVRLFSVAIAAVSMDKAGRKILLFVSAGVMLASNLTMGLYIHLVPSSQNSTIANRTLGSLASPAEPTNYITLIPLLAAMFFIMGYAMGWGPITWLLMSEILPLKARGVASGLCVVVSWLTAFALTQLFLGVVEFFGLEVPFLFFAVICAGNVLFTACCVPETKRRSLEQIEAFFRTGRKSFLRSFRR", "length": 509, "header": "tr|A0A8V1AHV9-1|A0A8V1AHV9_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 6 OS=Gallus gallus OX=9031 GN=SLC2A6 PE=1 SV=1 CANONICAL=A0A8V1AHV9-1" }, "locus": { "chromosome": "17", "start_pos": 7547356, "end_pos": 7543729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069837.1", "url": "https://www.ensembl.org/id/ENSGALT00010069837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042963.1", "url": "https://www.ensembl.org/id/ENSGALP00010042963.1" } ] } }, { "isoform_ac": "A0A8V1AK38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9/entry#A0A8V1AK38-1", "sequence": { "sequence": "MEPSVREPLVRRSSSSYHTFPESIRRGLDKEYLHLNNKRLYMAVFAAVLGNFSFGFALVYPSPVIPALETHPNPALRLDRYRASWFGSVFMLGAAAGGLSTMLLNDHLGRKLSIMFSAVPSAVGYALMASAQGIEMLLLGRVLTGYAGGVTSASIPVYISEISHPGVRGMLGTCPQIMAVLGSLILYVLGLLLDWRWLAVAGEVPVLTMILLLCFMPNSPRFLLSQGKEDEALRSLCWLRGKDTDYAQEYEQIKDSVRKQSQRISCAEIKDPFIYKPILIAVGMRFLQQLSGVTCVLVYLQPIFKKTAVILKPEYDAALVGLVRLFSVAIAAVSMDKAGRKILLFVSAGVMLASNLTMGLYIHLVPSSQNSTIANRTLGSLASPAEPTNYITLIPLLAAMFFIMGYAMGWGPITWLLMSEILPLKARGVASGLCVVVSWLTAFALTQLFLGVVEFFGLEKPNGGPWNRLRPFSGPVGSHS", "length": 480, "header": "tr|A0A8V1AK38-1|A0A8V1AK38_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 6 OS=Gallus gallus OX=9031 GN=SLC2A6 PE=4 SV=1 CANONICAL=A0A8V1AHV9-1" }, "locus": { "chromosome": "17", "start_pos": 7547356, "end_pos": 7543746, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069836.1", "url": "https://www.ensembl.org/id/ENSGALT00010069836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042962.1", "url": "https://www.ensembl.org/id/ENSGALP00010042962.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "resource": "Reactome", "description": "Cellular hexose transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480L693-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 6", "gene_name": "SLC2A6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQEPLLGAEGPDYDTFPEKPPPSPGERTRVGVLQSKRVLLAAFAAVLGNFSFGYSLVYASPVIPALEHSLDPNLSLTKTQASWFGSVFTLGAAAGGLSAMVLNDLLGRKLSIMFSALPSVAGYAFMAGAHGLWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEGPVLVMILLLSFMPNSPRFLLSRGRDSEALQALTWLRGADADIRWEFEQIQDNVRKQSSRMSWAEARDPHMYRPITIALVMRFLQQLTGITPILVYLQSIFDSTAVLLLPKYDAAIVGAVRLLSVLIAAVTMDLAGRKALLFVSGATMFAANLTLGLYVHFGPKALTPNSTMGMESVPVAGTEQPLVTPTSYLTLVPLLATMLFIMGYAMGWGPITWLLMAEILPLRARGVASGLCVLVSWLTAFALTKSFLPVVNAFGLQAPFFFFAAVCLVNLAFTGCCVPETKGRSLEQIESFFHSGRSVLH", "length": 506 }, "evidence": [ { "id": "A0A8V1AHV9", "url": "https://omabrowser.org/oma/group/A0A8V1AHV9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RB41-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 6", "gene_name": "slc2a6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADRSDEATPLINNSPPRISHGKLYLAVFSAVLGNFNFGFALVFPSPVIPQLKQGDDTRLQMNVHQISWFGSIFTLGAAAGGLSAMFLNDRVGRKISIMISGLPSVLGLLVMGSAQNFWMLLWGRFLTGIAGGITAGSIPVYVSEISHPSVRGALGSCPQITAVFGSLALYAFGLILPWRWLAVAGEVPVVIMMLLLCCMPTSPRYHIMKGNRAKAVKSLEWLRGPNSDYMTEFNKIERSITTQGVQWSDLKTKSYYKPILISVVMRFLQQMTGITPILVYLEPIFHLTAISLEPKYDAALVGAVRLISVAIAASLMDKAGRKALLFTSGFLIYIAMLSMTMYTHQTPCSQGNLTLTDGLNISSEVQAGAAFDPKTLIPLISAMVIIFGYAMGWGPITWLLMSEILPLGARGVASGLCVGVSWITAFVLTQLFMHVVVAYGLYVPFLFFCVVSVVNIIFTAKCVPETKGRTLEEIENYFRTGRSFTIHDP", "length": 490 }, "evidence": [ { "id": "A0A8V1AHV9", "url": "https://omabrowser.org/oma/group/A0A8V1AHV9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UDF0-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 6", "gene_name": "Slc2a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQEPLLRTEGLDYDTFPEVPATPGERERAGALKNRRVFLATFAAVLGNFSFGYALVYTSPVIPELKLSSDPALHLDKIQASWFGSVFTLGAAAGGLSAMLLNDLLGRKLSIMFSAVPSAIGYAIMAGARGLWMLLLGRMLTGFAGGLTAACIPVYVSEIAPPDVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEGPVLIMILLLSFMPNSPRFLLSKSRDEEALQALTWLRADSEVHWEFEQIQDNVRRQSSRVSWAEAREPRVYRPVLIAVLMRFLQQLTGITPILVYLQTIFDNTSVVLPSQQDAAIVGAVRLLSVLIAAVTMDLAGRKVLLYVSASVMFAANLTLGLYVQFVPRPLTPNSTVEIVTLGDTAFNYLTLIPLLATMLFIMGYAMGWGPITWLLMSEVLPLRARGVASGLCVLVSWLTAFVLTNYFLLAVNAFGLQVPFFFFSAICLLSLLFTGCCVPETRGRSLEQIEAFFHTRRMSFRP", "length": 497 }, "evidence": [ { "id": "A0A8V1AHV9", "url": "https://omabrowser.org/oma/group/A0A8V1AHV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGQ3-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 6", "gene_name": "SLC2A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQEPLLGAEGPDYDTFPEKPPPSPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSFLR", "length": 507 }, "evidence": [ { "id": "A0A8V1AHV9", "url": "https://omabrowser.org/oma/group/A0A8V1AHV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ZNS0-1", "protein_name": "Probable polyol transporter 3", "gene_name": "PLT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVHADGHNFPGSDPNPHMNKFAFGCAIVASIISIIFGYDTGVMSGAQIFIRDDLKINDTQIEVLAGILNLCALVGSLTAGKTSDVIGRRYTIALSAVIFLVGSVLMGYGPNYPVLMVGRCIAGVGVGFALMIAPVYSAEISSASHRGFLTSLPELCISLGILLGYVSNYCFGKLTLKLGWRLMLGIAAFPSLILAFGITRMPESPRWLVMQGRLEEAKKIMVLVSNTEEEAEERFRDILTAAEVDVTEIKEVGGGVKKKNHGKSVWRELVIKPRPAVRLILIAAVGIHFFEHATGIEAVVLYSPRIFKKAGVVSKDKLLLATVGVGLTKAFFIIIATFLLDKVGRRKLLLTSTGGMVFALTSLAVSLTMVQRFGRLAWALSLSIVSTYAFVAFFSIGLGPITWVYSSEIFPLRLRAQGASIGVAVNRIMNATVSMSFLSMTKAITTGGVFFVFAGIAVAAWWFFFFMLPETKGLPLEEMEKLFGGGGPRGDRDGLEIQTKTISIGGFS", "length": 508 }, "evidence": [ { "id": "A0A8V1AHV9", "url": "https://omabrowser.org/oma/group/A0A8V1AHV9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of glycolytic process", "id": "GO:0006110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHV9" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 485, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 356, "end_pos": 358 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHW0-1", "uniprot_ac": "A0A8V1AHW0", "uniprot_id": "A0A8V1AHW0_CHICK", "mass": { "chemical_mass": 39375.0, "monoisotopic_mass": 39375.0 }, "refseq": {}, "gene_names": [ { "name": "SLAMF8", "type": "recommended", "evidence": [ { "id": "A0A8V1AHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0" } ] } ], "protein_names": [ { "name": "SLAM family member 8", "type": "synonym", "evidence": [ { "id": "A0A8V1AHW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLAMF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0", "locus": { "chromosome": "25", "start_pos": 1144967, "end_pos": 1148510, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027842", "url": "https://www.ensembl.org/id/ENSGALG00010027842" } ] } } ], "crossref": [ { "id": "A0A8V1AHW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A5R5", "url": "https://www.orthodb.org/?gene=A0A8V1A5R5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHW0", "url": "https://www.orthodb.org/?gene=A0A8V1AHW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A5R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A5R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQLCDQRCPFIPRLLALLLVTTGTAAVQIKPVSGMLGDSVQLPLQLLPGDMVKRIIWSFRANASKKIELVEYNPETSEYPKYNRQQLKLINGTLQISALELNDSGVYDAQVTYQSTLMEECSFNLTVYEPVPEPLIQHEILSHSAPDCSIILRCLVPAGSGAQATWQHDNTSSALWRQSDDRHMLHVTIPTSTLNAIYTCVARNPVQEQSKSVDLAALCADGKAPHYLPLPHQVPRAIQPSQYLVPIEARRWRWPIYLAVLVAVLGALSIALYLLRRRGKAADRGWHCRGGAAGRQEGTIPIHHGLTFPTAVACPKEPLYSQVQRGNVEDRDEQGPSRTIYSEVGTGGDGTARLQA", "length": 357, "header": "tr|A0A8V1AHW0-1|A0A8V1AHW0_CHICK Isoform 1 of SLAM family member 8 OS=Gallus gallus OX=9031 GN=SLAMF8 PE=4 SV=1 CANONICAL=A0A8V1AHW0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A5R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0/entry#A0A8V1A5R5-1", "sequence": { "sequence": "MGQLCDQRCPFIPRLLALLLVTTARSSQADAPLCKSCSVLPGLHEAEARHPLLSNEWAQPLPARRLQGTAAVQIKPVSGMLGDSVQLPLQLLPGDMVKRIIWSFRANASKKIELVEYNPETSEYPKYNRQQLKLINGTLQISALELNDSGVYDAQVTYQSTLMEECSFNLTVYEPVPEPLIQHEILSHSAPDCSIILRCLVPAGSGAQATWQHDNTSSALWRQSDDRHMLHVTIPTSTLNAIYTCVARNPVQEQSKSVDLAALCADEARRWRWPIYLAVLVAVLGALSIALYLLRRRGKAADRAVACPKEPLYSQVQRGNVEDRDEQGPSRTIYSEVGTGGDGTARLQA", "length": 349, "header": "tr|A0A8V1A5R5-1|A0A8V1A5R5_CHICK Computationally mapped isoform of SLAM family member 8 OS=Gallus gallus OX=9031 GN=SLAMF8 PE=4 SV=1 CANONICAL=A0A8V1AHW0-1" }, "locus": { "chromosome": "25", "start_pos": 1148034, "end_pos": 1145138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067475.1", "url": "https://www.ensembl.org/id/ENSGALT00010067475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041239.1", "url": "https://www.ensembl.org/id/ENSGALP00010041239.1" } ] } }, { "isoform_ac": "A0A8V1AHW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHW0/entry#A0A8V1AHW0-1", "sequence": { "sequence": "MGQLCDQRCPFIPRLLALLLVTTGTAAVQIKPVSGMLGDSVQLPLQLLPGDMVKRIIWSFRANASKKIELVEYNPETSEYPKYNRQQLKLINGTLQISALELNDSGVYDAQVTYQSTLMEECSFNLTVYEPVPEPLIQHEILSHSAPDCSIILRCLVPAGSGAQATWQHDNTSSALWRQSDDRHMLHVTIPTSTLNAIYTCVARNPVQEQSKSVDLAALCADGKAPHYLPLPHQVPRAIQPSQYLVPIEARRWRWPIYLAVLVAVLGALSIALYLLRRRGKAADRGWHCRGGAAGRQEGTIPIHHGLTFPTAVACPKEPLYSQVQRGNVEDRDEQGPSRTIYSEVGTGGDGTARLQA", "length": 357, "header": "tr|A0A8V1AHW0-1|A0A8V1AHW0_CHICK Isoform 1 of SLAM family member 8 OS=Gallus gallus OX=9031 GN=SLAMF8 PE=4 SV=1 CANONICAL=A0A8V1AHW0-1" }, "locus": { "chromosome": "25", "start_pos": 1148034, "end_pos": 1145138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067478.1", "url": "https://www.ensembl.org/id/ENSGALT00010067478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041240.1", "url": "https://www.ensembl.org/id/ENSGALP00010041240.1" } ] } } ], "glycosylation": [], 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This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. 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] } ], "sequence": { "sequence": "MAAPALGALLLLGAAAVGGREVSMQYNPGWNGSSVNVLHVRAVGRSDALHYVWSTIGAPSVLLVATRSPDSALSIDWGRLLSPAPTGAVWIDPPGSVVYAAAVVFTKLFEYSNANASEEVFYPTYDLSDFSWDSINRTMNHTALTAELRGVPTSDSSGSFSNGSLAFRVTAYESGGRDGALPGLLHTANSSKVEFVLAGAAPRGNGSRFVLEVATVEERGAASRLRSVRSIDDEYTPTIFERWALRCFCSCWAPPRCSVPGGDPTANTSPSTERRRSARGAIAAAAGNTAPLSPLCLRFWGRAGQGGQWGPPPCRCAALRAAACTDGGASFLPAAHCRGLTGQRVRVIPVIVLILILLLGEGTSCCPASPKAAAMRGNSAAQRSDCFSSGPGRAFRSPRVTAGAAALPRAAMVGGGAAPFPRPQPLTHF", "length": 429, "header": "tr|A0A8V1AHX4-1|A0A8V1AHX4_CHICK Isoform 1 of Glycosylated lysosomal membrane protein OS=Gallus gallus OX=9031 GN=GLMP PE=1 SV=1 CANONICAL=A0A8V1AHX4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHX4/entry#A0A8V1A7W6-1", "sequence": { "sequence": "MCCAGRRMAAPALGALLLLGAAAVGGREVSMQYNPGWNGSSVNVLHVRAVGRSDALHYVWSTIGAPSVLLVATRSPDSALSIDWGRLLSPAPTGAVWIDPPGSVVYAAAVVFTKLFEYSNANASEEVFYPTYDLSDFSWDSINRTMNHTALTAELRGVPTSDSSGSFSNGSLAFRVTAYESGGRDGALPGLLHTANSSKVEFVLAGAAPRGNGSRFVLEVATVEERGAASRLRSVRSIDDEYTPTIFETLSLVAESPNDSSPLSFLQWKATAYGSQHPTRGDGIRCRAGGLRAAGGTRPPSAIVRAYFGDGAGSAYSVSAINVSFGGEDGGAYQERRYLSWSALLGFGLPPEDAFSPLIVSIVAAALGAPLLLLLLGAAALLCARRRPYSEYEPIN", "length": 396, "header": "tr|A0A8V1A7W6-1|A0A8V1A7W6_CHICK Computationally mapped isoform of Glycosylated lysosomal membrane protein OS=Gallus gallus OX=9031 GN=GLMP PE=1 SV=1 CANONICAL=A0A8V1AHX4-1" }, "locus": { "chromosome": "25", "start_pos": 32773, "end_pos": 29093, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068303.1", "url": "https://www.ensembl.org/id/ENSGALT00010068303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042046.1", "url": "https://www.ensembl.org/id/ENSGALP00010042046.1" } ] } }, { "isoform_ac": "A0A8V1AHX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHX4/entry#A0A8V1AHX4-1", "sequence": { "sequence": "MAAPALGALLLLGAAAVGGREVSMQYNPGWNGSSVNVLHVRAVGRSDALHYVWSTIGAPSVLLVATRSPDSALSIDWGRLLSPAPTGAVWIDPPGSVVYAAAVVFTKLFEYSNANASEEVFYPTYDLSDFSWDSINRTMNHTALTAELRGVPTSDSSGSFSNGSLAFRVTAYESGGRDGALPGLLHTANSSKVEFVLAGAAPRGNGSRFVLEVATVEERGAASRLRSVRSIDDEYTPTIFERWALRCFCSCWAPPRCSVPGGDPTANTSPSTERRRSARGAIAAAAGNTAPLSPLCLRFWGRAGQGGQWGPPPCRCAALRAAACTDGGASFLPAAHCRGLTGQRVRVIPVIVLILILLLGEGTSCCPASPKAAAMRGNSAAQRSDCFSSGPGRAFRSPRVTAGAAALPRAAMVGGGAAPFPRPQPLTHF", "length": 429, "header": "tr|A0A8V1AHX4-1|A0A8V1AHX4_CHICK Isoform 1 of Glycosylated lysosomal membrane protein OS=Gallus gallus OX=9031 GN=GLMP PE=1 SV=1 CANONICAL=A0A8V1AHX4-1" }, "locus": { "chromosome": "25", "start_pos": 32752, "end_pos": 28621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068301.1", "url": "https://www.ensembl.org/id/ENSGALT00010068301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042044.1", "url": "https://www.ensembl.org/id/ENSGALP00010042044.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 86, "start_aa": "Thr", "end_pos": 86, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr86", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": 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], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 86 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": 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"table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AK61-1", "uniprot_ac": "A0A8V1AK61", "uniprot_id": "A0A8V1AK61_CHICK", "mass": { "chemical_mass": 14105.0, "monoisotopic_mass": 14105.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121107574", "type": "recommended", "evidence": [ { "id": "A0A8V1AK61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AK61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121107574", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61", "locus": {} } ], "crossref": [ { "id": "A0A8V1AK61", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AK61", "database": "AlphaFoldDB", "categories": [] }, { "id": "121107574", "url": "https://www.ncbi.nlm.nih.gov/gene/121107574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395095", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395095", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRYSHGH", "url": "https://omabrowser.org/oma/group/NRYSHGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "WGEVTVM", "url": "https://omabrowser.org/oma/group/WGEVTVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "YTGYSHR", "url": "https://omabrowser.org/oma/group/YTGYSHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFW2", "url": "https://www.orthodb.org/?gene=A0A8V1AFW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "H9L3N2", "url": "https://www.orthodb.org/?gene=H9L3N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L3N2", "url": "https://www.uniprot.org/uniprotkb/H9L3N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H9L3N2-1", "url": "https://www.uniprot.org/uniprotkb/H9L3N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCSSLCAPACGVATPTPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSSPQYAAVGSAGVPTVGSGMGGTFGRSAGFGGYGGLGGYGGYGGLGGYGGYGGLGGYGGYGGFYGLGGYGGYGSCGYGGWSRGHRYLSGNCGPC", "length": 147, "header": "tr|A0A8V1AK61-1|A0A8V1AK61_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121107574 PE=3 SV=1 CANONICAL=A0A8V1AK61-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61/entry#A0A8V1AFW2-1", "sequence": { "sequence": "MSCSSLCAPACGVATPTPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSFPQNAVVGSAGVPAVGSGMGGTFGRSAGFGGYGGLGGYGGLGGYGGYGGFYGLGSYGGYGGYGSCGYGGWSRGHRYLSGNCGPC", "length": 138, "header": "tr|A0A8V1AFW2-1|A0A8V1AFW2_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC121107574 PE=3 SV=1 CANONICAL=A0A8V1AK61-1" }, "locus": { "chromosome": "25", "start_pos": 1584500, "end_pos": 1579686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069865.1", "url": "https://www.ensembl.org/id/ENSGALT00010069865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042991.1", "url": "https://www.ensembl.org/id/ENSGALP00010042991.1" } ] } }, { "isoform_ac": "A0A8V1AHY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61/entry#A0A8V1AHY1-1", "sequence": { "sequence": "MSCSSLCAPACGVATPTPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSFPQNAVVGSAGVPAVGSGMGGTFGRSAGFGGYGGLGGYGGLGGYGGYGGFYGLGGYGGYGSCGYGGWSRGHRYLSGNCGPC", "length": 135, "header": "tr|A0A8V1AHY1-1|A0A8V1AK61_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC121107574 PE=3 SV=1 CANONICAL=A0A8V1AK61-1" }, "locus": { "chromosome": "25", "start_pos": 1584500, "end_pos": 1584096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069862.1", "url": "https://www.ensembl.org/id/ENSGALT00010069862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042988.1", "url": "https://www.ensembl.org/id/ENSGALP00010042988.1" } ] } }, { "isoform_ac": "A0A8V1AHY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61/entry#A0A8V1AHY5-1", "sequence": { "sequence": "MSCSSLCAPACGVATPAPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSFPQNAVVGSAGVPAVGSGMGGTFGRGAGFGGYGGLGGYGGYGGFYGLGGYGGYGSCGYGGWSRGHRYLSGNCGPC", "length": 129, "header": "tr|A0A8V1AHY5-1|A0A8V1AHY5_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC121107574 PE=3 SV=1 CANONICAL=A0A8V1AK61-1" }, "locus": { "chromosome": "25", "start_pos": 1580099, "end_pos": 1575291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069867.1", "url": "https://www.ensembl.org/id/ENSGALT00010069867.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042993.1", "url": "https://www.ensembl.org/id/ENSGALP00010042993.1" } ] } }, { "isoform_ac": "A0A8V1AK61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61/entry#A0A8V1AK61-1", "sequence": { "sequence": "MSCSSLCAPACGVATPTPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSSPQYAAVGSAGVPTVGSGMGGTFGRSAGFGGYGGLGGYGGYGGLGGYGGYGGLGGYGGYGGFYGLGGYGGYGSCGYGGWSRGHRYLSGNCGPC", "length": 147, "header": "tr|A0A8V1AK61-1|A0A8V1AK61_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC121107574 PE=3 SV=1 CANONICAL=A0A8V1AK61-1" }, "locus": { "chromosome": "25", "start_pos": 1580099, "end_pos": 1570993, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069866.1", "url": "https://www.ensembl.org/id/ENSGALT00010069866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042992.1", "url": "https://www.ensembl.org/id/ENSGALP00010042992.1" } ] } }, { "isoform_ac": "H9L3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61/entry#H9L3N2-1", "sequence": { "sequence": "MSCSSLCAPACGVATPAPLADSCNEPCVRQCPDSTVVIQPPATVVTFPGPILSSFPQNAVVGSAGVPAVGSGMGGTFGRGAGFGGYGGLGGYGGYGGLGGYGGYGGFYGLGGYGGYGSCGYGGWSRGHRYLSGNCGPC", "length": 138, "header": "tr|H9L3N2-1|H9L3N2_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC121107574 PE=3 SV=2 CANONICAL=A0A8V1AK61-1" }, "locus": { "chromosome": "25", "start_pos": 1580099, "end_pos": 1575291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069864.1", "url": "https://www.ensembl.org/id/ENSGALT00010069864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042990.1", "url": "https://www.ensembl.org/id/ENSGALP00010042990.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395095", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395095", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHY6-1", "uniprot_ac": "A0A8V1AHY6", "uniprot_id": "A0A8V1AHY6_CHICK", "mass": { "chemical_mass": 81701.0, "monoisotopic_mass": 81701.0 }, "refseq": {}, "gene_names": [ { "name": "GPSM1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ] } ], "protein_names": [ { "name": "G protein signaling modulator 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AHY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPSM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6", "locus": { "chromosome": "17", "start_pos": 8528511, "end_pos": 8590970, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028189", "url": "https://www.ensembl.org/id/ENSGALG00010028189" } ] } } ], "crossref": [ { "id": "A0A8V1AHY6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "417132", "url": "https://www.ncbi.nlm.nih.gov/gene/417132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417132", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417132", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7X5", "url": "https://www.orthodb.org/?gene=A0A8V1A7X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFM5", "url": "https://www.orthodb.org/?gene=A0A8V1AFM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFN0", "url": "https://www.orthodb.org/?gene=A0A8V1AFN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHY6", "url": "https://www.orthodb.org/?gene=A0A8V1AHY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJT5", "url": "https://www.orthodb.org/?gene=A0A8V1AJT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45954", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45954", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45954:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45954:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13374", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13374", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7X5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVGALGYVPKPYSSNPMPPRKASCCCCSVSVASGPDSEEERSAKTLKNCSSFPGHTCHSQHTTPRGCHSPDELRAFLKLWGFLLSAHRMEASCLELALEGERLCKAGDFKAGAAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLKEYSKALEYHKHDLTLARTIGDRIGEAKASGNLGNTLKILGQFDEAVVCCQRHLDISQEQGDKIGEARALYNIGNVYHAKGKHLSWNMAQDPGYLPQEVKETLQKASEYYERNLSLVKELGDRAAQGRAYGNLGNTQYLLGNFSEAIAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDISAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYEKAIEYHLKHLVIAQELGDRVGEGRACWSLGNAYVSLGSHEQALHFARKHLEISQEIGDRTGELTAQVNMAQLRAALGLGPGDEEVGMARPYSGYEAQGARPKRVQRNSMDSLDLLKFPSEKDQNGDSHHVGDLKISGKEFLSLPARSKKYREHHLGLERRPHGQCASPLDSSQVQVQVPQPKINRTPSDEECFFDLLSKFQSNRMDDQRCPLEECPSEAAEAAATPVPALEERIPHSSLMASPQTEEFFDLIASSQSRRLDDQRANVGNLPGLRITHNNLGHLCMEGDAQEPGDEFFNMLMKCQSSRIDDQRCAPPDSIPRGPTMPDEDFFSLIQRVQAKRMDEQRVDLASAQEEAEEEQQRPGSS", "length": 735, "header": "tr|A0A8V1AHY6-1|A0A8V1AHY6_CHICK Isoform 1 of G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=GPSM1 PE=1 SV=1 CANONICAL=A0A8V1AHY6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6/entry#A0A8V1A7X5-1", "sequence": { "sequence": "MAGAPGGDSPGSAARRLYSRMEASCLELALEGERLCKAGDFKAGAAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLKEYSKALEYHKHDLTLARTIGDRIGEAKASGNLGNTLKILGQFDEAVVCCQRHLDISQEQGDKIGEARALYNIGNVYHAKGKHLSWNMAQDPGYLPQEVKETLQKASEYYERNLSLVKELGDRAAQGRAYGNLGNTQYLLGNFSEAIAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDISAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYEKAIEYHLKHLVIAQELGDRVGEGRACWSLGNAYVSLGSHEQALHFARKHLEISQEIGDRTGELTAQVNMAQLRAALGLGPGDEEVGMARPYSGYEAQGARPKRVQRNSMDSLDLLKFPSEKDQNGDSHHVGDLKISGKEFLSLPARSKKYREHHLGLERRPHGQCASPLDSSQVQVQVPQPKINRTPSDEECFFDLLSKFQSNRMDDQRCPLEECPSEAAEAAATPVPALEERIRKRGAHSSLMASPQTEEFFDLIASSQSRRLDDQRANVGNLPGLRITHNNLGHLCMEGDAQEPGDEFFNMLMKCQSSRIDDQRCAPPDSIPRGPTMPDEDFFSLIQRVQAKRMDEQRVDLASAQEEAEEEQQRPGSS", "length": 670, "header": "tr|A0A8V1A7X5-1|A0A8V1A7X5_CHICK Computationally mapped isoform of G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=GPSM1 PE=1 SV=1 CANONICAL=A0A8V1AHY6-1" }, "locus": { "chromosome": "17", "start_pos": 8580664, "end_pos": 8530467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068313.1", "url": "https://www.ensembl.org/id/ENSGALT00010068313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042056.1", "url": "https://www.ensembl.org/id/ENSGALP00010042056.1" } ] } }, { "isoform_ac": "A0A8V1AFM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6/entry#A0A8V1AFM5-1", "sequence": { "sequence": "MPSASSKPQLPLVSSAVRAVCKTVPGGAQPCSLLLPVGLELWVYVQKMRRLQKRRMEASCLELALEGERLCKAGDFKAGAAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLKEYSKALEYHKHDLTLARTIGDRIGEAKASGNLGNTLKILGQFDEAVVCCQRHLDISQEQGDKIGEARALYNIGNVYHAKGKHLSWNMAQDPGYLPQEVKETLQKASEYYERNLSLVKELGDRAAQGRAYGNLGNTQYLLGNFSEAIAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDISAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYEKAIEYHLKHLVIAQELGDRVGEGRACWSLGNAYVSLGSHEQALHFARKHLEISQEIGDRTGELTAQVNMAQLRAALGLGPGDEEVGMARPYSGYEAQGARPKRVQRNSMDSLDLLKFPSEKDQNGDSHHVGDLKISGKEFLSLPARSKKYREHHLGLERRPHGQCASPLDSSQVQVQVPQPKINRTPSDEECFFDLLSKFQSNRMDDQRCPLEECPSEAAEAAATPVPALEERIPHSSLMASPQTEEFFDLIASSQSRRLDDQRANVGNLPGLRITHNNLGHLCMEGDAQEPGDEFFNMLMKCQSSRIDDQRCAPPDSIPRGPTMPDEDFFSLIQRVQAKRMDEQRVDLASAQEEAEEEQQRPGSS", "length": 701, "header": "tr|A0A8V1AFM5-1|A0A8V1AFM5_CHICK Computationally mapped isoform of G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=GPSM1 PE=1 SV=1 CANONICAL=A0A8V1AHY6-1" }, "locus": { "chromosome": "17", "start_pos": 8568600, "end_pos": 8530467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068312.1", "url": "https://www.ensembl.org/id/ENSGALT00010068312.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042055.1", "url": "https://www.ensembl.org/id/ENSGALP00010042055.1" } ] } }, { "isoform_ac": "A0A8V1AFN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6/entry#A0A8V1AFN0-1", "sequence": { "sequence": "MGRLPALCRGMWESTRLPWKPAIVNGALQLQGRIYSTRQFKSAIRRMEASCLELALEGERLCKAGDFKAGAAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLKEYSKALEYHKHDLTLARTIGDRIGEAKASGNLGNTLKILGQFDEAVVCCQRHLDISQEQGDKIGEARALYNIGNVYHAKGKHLSWNMAQDPGYLPQEVKETLQKASEYYERNLSLVKELGDRAAQGRAYGNLGNTQYLLGNFSEAIAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDISAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYEKAIEYHLKHLVIAQELGDRVGEGRACWSLGNAYVSLGSHEQALHFARKHLEISQEIGDRTGELTAQVNMAQLRAALGLGPGDEEVGMARPYSGYEAQGARPKRVQRNSMDSLDLLKFPSEKDQNGDSHHVGDLKISGKEFLSLPARSKKYREHHLGLERRPHGQCASPLDSSQVQVQVPQPKINRTPSDEECFFDLLSKFQSNRMDDQRCPLEECPSEAAEAAATPVPALEERIPHSSLMASPQTEEFFDLIASSQSRRLDDQRANVGNLPGLRITHNNLGHLCMEGDAQEPGDEFFNMLMKCQSSRIDDQRCAPPDSIPRGPTMPDEDFFSLIQRVQAKRMDEQRVDLASAQEEAEEEQQRPGSS", "length": 692, "header": "tr|A0A8V1AFN0-1|A0A8V1AFN0_CHICK Computationally mapped isoform of G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=GPSM1 PE=1 SV=1 CANONICAL=A0A8V1AHY6-1" }, "locus": { "chromosome": "17", "start_pos": 8587639, "end_pos": 8530467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068317.1", "url": "https://www.ensembl.org/id/ENSGALT00010068317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042060.1", "url": "https://www.ensembl.org/id/ENSGALP00010042060.1" } ] } }, { "isoform_ac": "A0A8V1AHY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6/entry#A0A8V1AHY6-1", "sequence": { "sequence": "MEVGALGYVPKPYSSNPMPPRKASCCCCSVSVASGPDSEEERSAKTLKNCSSFPGHTCHSQHTTPRGCHSPDELRAFLKLWGFLLSAHRMEASCLELALEGERLCKAGDFKAGAAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLKEYSKALEYHKHDLTLARTIGDRIGEAKASGNLGNTLKILGQFDEAVVCCQRHLDISQEQGDKIGEARALYNIGNVYHAKGKHLSWNMAQDPGYLPQEVKETLQKASEYYERNLSLVKELGDRAAQGRAYGNLGNTQYLLGNFSEAIAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDISAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYEKAIEYHLKHLVIAQELGDRVGEGRACWSLGNAYVSLGSHEQALHFARKHLEISQEIGDRTGELTAQVNMAQLRAALGLGPGDEEVGMARPYSGYEAQGARPKRVQRNSMDSLDLLKFPSEKDQNGDSHHVGDLKISGKEFLSLPARSKKYREHHLGLERRPHGQCASPLDSSQVQVQVPQPKINRTPSDEECFFDLLSKFQSNRMDDQRCPLEECPSEAAEAAATPVPALEERIPHSSLMASPQTEEFFDLIASSQSRRLDDQRANVGNLPGLRITHNNLGHLCMEGDAQEPGDEFFNMLMKCQSSRIDDQRCAPPDSIPRGPTMPDEDFFSLIQRVQAKRMDEQRVDLASAQEEAEEEQQRPGSS", "length": 735, "header": "tr|A0A8V1AHY6-1|A0A8V1AHY6_CHICK Isoform 1 of G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=GPSM1 PE=1 SV=1 CANONICAL=A0A8V1AHY6-1" }, "locus": { "chromosome": "17", "start_pos": 8584162, "end_pos": 8530467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068316.1", "url": "https://www.ensembl.org/id/ENSGALT00010068316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042059.1", "url": "https://www.ensembl.org/id/ENSGALP00010042059.1" } ] } }, { "isoform_ac": "A0A8V1AJT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6/entry#A0A8V1AJT5-1", "sequence": { "sequence": "MQDFFLMQMEASCLELALEGERLCKAGDFKAGAAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLKEYSKALEYHKHDLTLARTIGDRIGEAKASGNLGNTLKILGQFDEAVVCCQRHLDISQEQGDKIGEARALYNIGNVYHAKGKHLSWNMAQDPGYLPQEVKETLQKASEYYERNLSLVKELGDRAAQGRAYGNLGNTQYLLGNFSEAIAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDISAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYEKAIEYHLKHLVIAQELGDRVGEGRACWSLGNAYVSLGSHEQALHFARKHLEISQEIGDRTGELTAQVNMAQLRAALGLGPGDEEVGMARPYSGYEAQGARPKRVQRNSMDSLDLLKFPSEKDQNGDSHHVGDLKISGKEFLSLPARSKKYREHHLGLERRPHGQCASPLDSSQVQVQVPQPKINRTPSDEECFFDLLSKFQSNRMDDQRCPLEECPSEAAEAAATPVPALEERIPHSSLMASPQTEEFFDLIASSQSRRLDDQRANVGNLPGLRITHNNLGHLCMEGDAQEPGDEFFNMLMKCQSSRIDDQRCAPPDSIPRGPTMPDEDFFSLIQRVQAKRMDEQRVDLASAQEEAEEEQQRPGSS", "length": 654, "header": "tr|A0A8V1AJT5-1|A0A8V1AJT5_CHICK Computationally mapped isoform of G protein signaling modulator 1 OS=Gallus gallus OX=9031 GN=GPSM1 PE=1 SV=1 CANONICAL=A0A8V1AHY6-1" }, "locus": { "chromosome": "17", "start_pos": 8565902, "end_pos": 8530467, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068314.1", "url": "https://www.ensembl.org/id/ENSGALT00010068314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042057.1", "url": "https://www.ensembl.org/id/ENSGALP00010042057.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417132", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417132", "resource": "KEGG Pathway" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G-protein alpha-subunit binding", "id": "GO:0001965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" }, { "name": "GDP-dissociation inhibitor activity", "id": "GO:0005092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" }, { "name": "GTPase regulator activity", "id": "GO:0030695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030695", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 553, "end_pos": 555 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHZ1-1", "uniprot_ac": "A0A8V1AHZ1", "uniprot_id": "A0A8V1AHZ1_CHICK", "mass": { "chemical_mass": 72212.0, "monoisotopic_mass": 72212.0 }, "refseq": {}, "gene_names": [ { "name": "KLHL26", "type": "recommended", "evidence": [ { "id": "A0A8V1AHZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1" } ] } ], "protein_names": [ { "name": "Kelch like family member 26", "type": "synonym", "evidence": [ { "id": "A0A8V1AHZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1", "locus": { "chromosome": "28", "start_pos": 4296829, "end_pos": 4311730, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028191", "url": "https://www.ensembl.org/id/ENSGALG00010028191" } ] } } ], "crossref": [ { "id": "A0A8V1AHZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000033270", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000033270", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18255", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18255", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18465", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18465", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420121", "url": "https://www.ncbi.nlm.nih.gov/gene/420121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420121", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420121", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "INREAFH", "url": "https://omabrowser.org/oma/group/INREAFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NYT7", "url": "https://www.orthodb.org/?gene=A0A1D5NYT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7Y7", "url": "https://www.orthodb.org/?gene=A0A8V1A7Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFN4", "url": "https://www.orthodb.org/?gene=A0A8V1AFN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHZ1", "url": "https://www.orthodb.org/?gene=A0A8V1AHZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJU0", "url": "https://www.orthodb.org/?gene=A0A8V1AJU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5NYT7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NYT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NYT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSGHAEKSVRVWKTGGGLFCTAGCPGLCCGVRCAWSQAAREGVWMSGMGPRLPEGFSMADKNSTLKCTFSAPGHSTTLLQGLASLRAQAQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSAKGLKHIIDFAYSAEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLASLKESVDAFTFRHFLQISEEEDFLHLPLERLVFFLQSNKLQSCSEIDLFRAAVRWLQYDPTRRASASQVLCHIRFPLMKSSELVDNVQTFDIMVEDVLCRQYLLEAFNYQILPFRQHEMQSPRTTIRSDVLSLITFGGTPYTDNDRTVSCKVYCLPDASGRQFKELTEMEVGSSHSCVAVLDNFVYIVGGQHLQYRSGEGAVDICYRYDPHLNQWLRIQAMQESRIQFQLNVLHGMVYATGGRNRSGSLASVEKYCPKDNEWTYVCSLKRRTWGHAGATVGDKLYISGGYGISVEDKKALHCYDPAVDQWEFKTPMNEPRVLHAMVSANGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTTVSPMRAGQSEAGCCLLEKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACAPVILPQITTPR", "length": 645, "header": "tr|A0A8V1AHZ1-1|A0A8V1AHZ1_CHICK Isoform 1 of Kelch like family member 26 OS=Gallus gallus OX=9031 GN=KLHL26 PE=4 SV=1 CANONICAL=A0A8V1AHZ1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NYT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1/entry#A0A1D5NYT7-1", "sequence": { "sequence": "MAESGGAEFGAERPSSMADKNSTLKCTFSAPGHSTTLLQGLASLRAQAQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSAKGLKHIIDFAYSAEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLASLKESVDAFTFRHFLQISEEEDFLHLPLERLVFFLQSNKLQSCSEIDLFRAAVRWLQYDPTRRASASQVLCHIRFPLMKSSELVDNVQTFDIMVEDVLCRQYLLEAFNYQILPFRQHEMQSPRTTIRSDVLSLITFGGTPYTDNDRTVSCKVYCLPDASGRQFKELTEMEVGSSHSCVAVLDNFVYIVGGQHLQYRSGEGAVDICYRYDPHLNQWLRIQAMQESRIQFQLNVLHGMVYATGGRNRSGSLASVEKYCPKDNEWTYVCSLKRRTWGHAGATVGDKLYISGGYGISVEDKKALHCYDPAVDQWEFKTPMNEPRVLHAMVSANGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTTVSPMRAGQSEAGCCLLEKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACAPVILPQITTPR", "length": 603, "header": "tr|A0A1D5NYT7-1|A0A1D5NYT7_CHICK Computationally mapped isoform of Kelch like family member 26 OS=Gallus gallus OX=9031 GN=KLHL26 PE=4 SV=2 CANONICAL=A0A8V1AHZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4311621, "end_pos": 4298437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068324.1", "url": "https://www.ensembl.org/id/ENSGALT00010068324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042067.1", "url": "https://www.ensembl.org/id/ENSGALP00010042067.1" } ] } }, { "isoform_ac": "A0A8V1A7Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1/entry#A0A8V1A7Y7-1", "sequence": { "sequence": "MAESGGAEFGAERPSSMADKNSTLKCTFSAPGHSTTLLQGLASLRAQAQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSAKGLKHIIDFAYSAEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLASLKESVDAFTFRHFLQISEEEDFLHLPLERLVFFLQSNKLQSCSEIDLFRAAVRWLQYDPTRRASASQVLCHIRFPLMKSSELVDNVQTFDIMVEDVLCRQYLLEAFNYQILPFRQHEMQSPRTTIRSDVLSLITFGGTPYTDNDRTVSCKVYCLPDASGRQFKELTEMEVGSSHSCVAVLDNFVYIVGGQHLQYRSGEGAVDICYRYDPHLNQWLRIQFQLNVLHGMVYATGGRNRSGSLASVEKYCPKDNEWTYVCSLKRRTWGHAGATVGDKLYISGGYGISVEDKKALHCYDPAVDQWEFKTPMNEPRVLHAMVSANGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTTVSPMRAGQSEAGCCLLEKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACAPVILPQITTPR", "length": 595, "header": "tr|A0A8V1A7Y7-1|A0A8V1A7Y7_CHICK Computationally mapped isoform of Kelch like family member 26 OS=Gallus gallus OX=9031 GN=KLHL26 PE=4 SV=1 CANONICAL=A0A8V1AHZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4311621, "end_pos": 4298437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068323.1", "url": "https://www.ensembl.org/id/ENSGALT00010068323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042066.1", "url": "https://www.ensembl.org/id/ENSGALP00010042066.1" } ] } }, { "isoform_ac": "A0A8V1AFN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1/entry#A0A8V1AFN4-1", "sequence": { "sequence": "MDGGPAGLSYLMADKNSTLKCTFSAPGHSTTLLQGLASLRAQAQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSAKGLKHIIDFAYSAEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLASLKESVDAFTFRHFLQISEEEDFLHLPLERLVFFLQSNKLQSCSEIDLFRAAVRWLQYDPTRRASASQVLCHIRFPLMKSSELVDNVQTFDIMVEDVLCRQYLLEAFNYQILPFRQHEMQSPRTTIRSDVLSLITFGGTPYTDNDRTVSCKVYCLPDASGRQFKELTEMEVGSSHSCVAVLDNFVYIVGGQHLQYRSGEGAVDICYRYDPHLNQWLRIQAMQESRIQFQLNVLHGMVYATGGRNRSGSLASVEKYCPKDNEWTYVCSLKRRTWGHAGATVGDKLYISGGYGISVEDKKALHCYDPAVDQWEFKTPMNEPRVLHAMVSANGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTTVSPMRAGQSEAGCCLLEKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACAPVILPQITTPR", "length": 598, "header": "tr|A0A8V1AFN4-1|A0A8V1AFN4_CHICK Computationally mapped isoform of Kelch like family member 26 OS=Gallus gallus OX=9031 GN=KLHL26 PE=4 SV=1 CANONICAL=A0A8V1AHZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4309739, "end_pos": 4298437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068322.1", "url": "https://www.ensembl.org/id/ENSGALT00010068322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042065.1", "url": "https://www.ensembl.org/id/ENSGALP00010042065.1" } ] } }, { "isoform_ac": "A0A8V1AHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1/entry#A0A8V1AHZ1-1", "sequence": { "sequence": "MSSGHAEKSVRVWKTGGGLFCTAGCPGLCCGVRCAWSQAAREGVWMSGMGPRLPEGFSMADKNSTLKCTFSAPGHSTTLLQGLASLRAQAQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSAKGLKHIIDFAYSAEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLASLKESVDAFTFRHFLQISEEEDFLHLPLERLVFFLQSNKLQSCSEIDLFRAAVRWLQYDPTRRASASQVLCHIRFPLMKSSELVDNVQTFDIMVEDVLCRQYLLEAFNYQILPFRQHEMQSPRTTIRSDVLSLITFGGTPYTDNDRTVSCKVYCLPDASGRQFKELTEMEVGSSHSCVAVLDNFVYIVGGQHLQYRSGEGAVDICYRYDPHLNQWLRIQAMQESRIQFQLNVLHGMVYATGGRNRSGSLASVEKYCPKDNEWTYVCSLKRRTWGHAGATVGDKLYISGGYGISVEDKKALHCYDPAVDQWEFKTPMNEPRVLHAMVSANGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTTVSPMRAGQSEAGCCLLEKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACAPVILPQITTPR", "length": 645, "header": "tr|A0A8V1AHZ1-1|A0A8V1AHZ1_CHICK Isoform 1 of Kelch like family member 26 OS=Gallus gallus OX=9031 GN=KLHL26 PE=4 SV=1 CANONICAL=A0A8V1AHZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4309184, "end_pos": 4298437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068321.1", "url": "https://www.ensembl.org/id/ENSGALT00010068321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042064.1", "url": "https://www.ensembl.org/id/ENSGALP00010042064.1" } ] } }, { "isoform_ac": "A0A8V1AJU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1/entry#A0A8V1AJU0-1", "sequence": { "sequence": "MSLLCWDKGIQPSMADKNSTLKCTFSAPGHSTTLLQGLASLRAQAQLLDVILTINNEVFQVHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSAKGLKHIIDFAYSAEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLASLKESVDAFTFRHFLQISEEEDFLHLPLERLVFFLQSNKLQSCSEIDLFRAAVRWLQYDPTRRASASQVLCHIRFPLMKSSELVDNVQTFDIMVEDVLCRQYLLEAFNYQILPFRQHEMQSPRTTIRSDVLSLITFGGTPYTDNDRTVSCKVYCLPDASGRQFKELTEMEVGSSHSCVAVLDNFVYIVGGQHLQYRSGEGAVDICYRYDPHLNQWLRIQAMQESRIQFQLNVLHGMVYATGGRNRSGSLASVEKYCPKDNEWTYVCSLKRRTWGHAGATVGDKLYISGGYGISVEDKKALHCYDPAVDQWEFKTPMNEPRVLHAMVSANGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTTVSPMRAGQSEAGCCLLEKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACAPVILPQITTPR", "length": 600, "header": "tr|A0A8V1AJU0-1|A0A8V1AJU0_CHICK Computationally mapped isoform of Kelch like family member 26 OS=Gallus gallus OX=9031 GN=KLHL26 PE=4 SV=1 CANONICAL=A0A8V1AHZ1-1" }, "locus": { "chromosome": "28", "start_pos": 4303140, "end_pos": 4298437, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068319.1", "url": "https://www.ensembl.org/id/ENSGALT00010068319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042062.1", "url": "https://www.ensembl.org/id/ENSGALP00010042062.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420121", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LIM8-1", "protein_name": "Kelch-like family member 26", "gene_name": "Klhl26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFSTFNPTSAGSARCPGLGLRVRAPLHRSGARRKMAESGGSSGSGQSPERPSSLADRNGALKCTFSAAGHSTGLLQGLAALRAQGQLLDVVLTVNSEAFHAHKVVLAACSDYFRAMFTGGMREASQAVIQLQGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEDFLKAAMSVETCLHIGQMATTFSLTSLRESVDAFTFRHFLQIAAEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRARASLVLRHVRFPLMQPAELVDSVQTLDVMLDDALCRQYLLEAFSYHVLPCRQHDMQSPRTAVRSDVASLVAFGGTPYTDSDRAVSSKVFQLPEPGARHFRELTEMELGCSHAGVAVLDNFVYVAGGQHLQHRSGEGAVDACYRYDPQRNRWLRLRALRESRVQFQLTALGGLLYATGGRNRAGSLASVERYCPRRDSWDFACPLKRRTWGHAGAAAAGRLYISGGYGVSAEDKKALQCYDPAADRWEPRAPMREPRVLHAMLGAAGRIYALGGRMDHVDRCFDVLAVEYYVPDADQWTSVTPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTETDEWERDLHFPESFAGIACAAVLLPRSGHGR", "length": 641 }, "evidence": [ { "id": "A0A8V1AHZ1", "url": "https://omabrowser.org/oma/group/A0A8V1AHZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S905-1", "protein_name": "Kelch like family member 26", "gene_name": "KLHL26", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAESGGGGGAGGGGFSAGPGPERPSSMADKNGALKCTFSAPGHSTSLLQGLAALRAQGQLLDVVLTINQETFHAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGHMATTFSLASLKESVDAFTFRHFLQIAEEEDFLHLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRQRASHVLCHIRFPLMRSSDLVDSVQTLDIMVEDVLCRQYLLEAFNYQVLPFRQHEMQSPRTAVRSDVPSLVAFGGTPYTDSDRSVSSKVYQLPEPGARHFRELTEMEVGCSHTCVAVLDNFVYVAGGQHLQYRSGEGAVDACYRYDPHLNRWLRLQAMQESRIQFQLNVLCGMVYATGGRNRAGSLASVERYCPRRNEWGYACSLKRRTWGHAGASAGGRLYISGGYGISVEDKKALHCYDPEADQWEFKAPMSEPRVLHAMVGAGGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTSVSPMRAGQSEAGCCLLDRKIYIVGGYNWRLNNVTGIVQVYNTETDEWERDLHFPESFAGIACAPVLLPRAGTRR", "length": 613 }, "evidence": [ { "id": "A0A8V1AHZ1", "url": "https://omabrowser.org/oma/group/A0A8V1AHZ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q53HC5-1", "protein_name": "Kelch-like protein 26", "gene_name": "KLHL26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESGGSSGGAGGGGAFGAGPGPERPNSTADKNGALKCTFSAPSHSTSLLQGLATLRAQGQLLDVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGQMATTFSLASLRESVDAFTFRHFLQIAEEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRPRASHVLCHIRFPLMQSSELVDSVQTLDIMVEDVLCRQYLLEAFNYQVLPFRQHEMQSPRTAVRSDVPSLVTFGGTPYTDSDRSVSSKVYQLPEPGARHFRELTEMEVGCSHTCVAVLDNFVYVAGGQHLQYRSGEGAVDACYRYDPHLNRWLRLQAMQESRIQFQLNVLCGMVYATGGRNRAGSLASVERYCPRRNEWGYACSLKRRTWGHAGAASGGRLYISGGYGISVEDKKALHCYDPVADQWEFKAPMSEPRVLHAMVGAGGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTSVSPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTDTDEWERDLHFPESFAGIACAPVLLPRAGTRR", "length": 615 }, "evidence": [ { "id": "A0A8V1AHZ1", "url": "https://omabrowser.org/oma/group/A0A8V1AHZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RGB8-1", "protein_name": "Kelch-like protein 26", "gene_name": "klhl26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESDGVEFFANRAQSSMADNKNSVLRCTFSAPSHSSTLLRGLSALRDQGQLLDVVLAIDNERFEVHKAVLASCSDYFRAMFTGGMKESNQNTIELIGLSARGLKHIIDFAYSSEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLSSLKQSVDAYTFRHFLQIAQEDDFLHIPMERLTFFLQSNKLKNCSEIDLFHAAIRWLQHDASRRTVASEVLCHVRFPLMRSSELVDSVQIVDIMVEDVQCRHFLLEAFNYQILPFRQHEMQSPRTSIRSDITSLITFGGTPYTDNDRTVSSKVYFLPDITVRQFKELTEMEMGCSHACVSVLDNFVYVVGGQHLQYRSGEGAVDICFRYDPHLNQWLRIQPMQESRIQFQLNVLDGQLYATGGRNRSGSLSSVECYCPKKNEWTNVDSLKRRIWGHAGATCGDKLYISGGYGVSVEDKKTLHCYDSALDQWDFKCPMNEPRVLHAMISANNRIYALGGRMDHVDRCFDVLAVEYYIPETDQWTTVSPMRAGQSEAGCCLLDKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACTPIILPQTTTQR", "length": 605 }, "evidence": [ { "id": "A0A8V1AHZ1", "url": "https://omabrowser.org/oma/group/A0A8V1AHZ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BGY4-1", "protein_name": "Kelch-like protein 26", "gene_name": "Klhl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESGGSSGSSQSPERPSSLADRNGALKCTFSAAGHSTGLLQGLAALRAQGQLLDVVLTVNSEAFHAHKVVLAACSDYFRAMFTGGMREANQAVIQLQGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEDFLKAAMSVETCLHIGQMATTFSLTSLRESVDAFTFRHFLQIAAEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRARASLVLRHVRFPLMQPAELVDSVQTLDVMLDDALCRQYLLEAFSYHVLPCRQHDMQSPRTAVRSDVASLVAFGGTPYTDSDRAVSSKVFQLPEPGARHFRELTEMELGCSHAGVAVLDNFVYVAGGQHLQHRSGEGAVDACYRYDPQRNRWLRLRALRESRVQFQLTALGGLLYATGGRNRAGSLASVERYCPRRDSWDFACPLKRRTWGHAGAAAAGRLYISGGYGVSAEDKKALQCYDPAADRWEPRAPMREPRVLHAMLGAAGRIYALGGRMDHVDRCFDVLAVEYYVPDADQWTSVTPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTETDEWERDLHFPESFAGIACAAVLLPRSGHGR", "length": 606 }, "evidence": [ { "id": "A0A8V1AHZ1", "url": "https://omabrowser.org/oma/group/A0A8V1AHZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ1" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 160, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 452, "end_pos": 454 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHZ4-1", "uniprot_ac": "A0A8V1AHZ4", "uniprot_id": "A0A8V1AHZ4_CHICK", "mass": { "chemical_mass": 107447.0, "monoisotopic_mass": 107447.0 }, "refseq": { "ac": "XP_003642443", "name": "general transcription factor II-I repeat domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642443" }, "gene_names": [ { "name": "GTF2IRD1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ] }, { "name": "GTF2IRD1", "type": "synonym", "evidence": [ { "id": "XP_003642443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642443" } ] } ], "protein_names": [ { "name": "General transcription factor II-I repeat domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AHZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4/entry#names_and_taxonomy" } ] }, { "name": "general transcription factor II-I repeat domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003642443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642443" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003642443.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642443" } ] }, { "annotation": "May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY0#function" }, { "database": "UniProtKB", "id": "ARBA00058906", "url": "https://www.uniprot.org/uniprotkb/ARBA00058906#function" }, { "database": "UniProtKB", "id": "A0A8V1ALY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY8#function" }, { "database": "UniProtKB", "id": "A0A8V1ANH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANH8#function" }, { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4#function" }, { "database": "UniProtKB", "id": "A0A8V1ACN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTF2IRD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4", "locus": { "chromosome": "19", "start_pos": 3203948, "end_pos": 3254310, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029382", "url": "https://www.ensembl.org/id/ENSGALG00010029382" } ] } } ], "crossref": [ { "id": "A0A8V1AHZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "417487", "url": "https://www.ncbi.nlm.nih.gov/gene/417487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417487", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACN7", "url": "https://www.orthodb.org/?gene=A0A8V1ACN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHZ4", "url": "https://www.orthodb.org/?gene=A0A8V1AHZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJY0", "url": "https://www.orthodb.org/?gene=A0A8V1AJY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALY8", "url": "https://www.orthodb.org/?gene=A0A8V1ALY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANH8", "url": "https://www.orthodb.org/?gene=A0A8V1ANH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALAGRPLDVTLGSSRPEQWNMVFPQKDEIITSLVSALDSMCSALSKLNAEVACIAVHDENTFVLGTEKGRVFLSARKELQADFQKFCRVQQRREQDAEAQKKAKECGRSVLRVSPDQGSDVYLLRKMVEEVFDVLYSEAVGKSSVVPLPYERFLKEPGLLAVAGLPEGISFKKPMEYDVKSLMAILEHSHSIRFRLKRPADEPSREPNPSVELTCTSLVPKGGRDPGANSHTAKPSGQDAPPAVAVTNFLYGVSLPTQIAMDLKQEVSSGLHGATVASEVLLPRPSGELKVPSSQEYSDCCGQKSAVSGGPLIQNVHSSKRILFSIVHDKTDKWDSFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHNIHFVIKRMFDERIFTGSKFTKDPTKLEPSSPPGEISPEPHRGAVLDLAGTSQAASRSEKCSLPESCEPGTSGELGGIRQIKIEPDELDIIQITVPDRSPGSDEMHDPATTHVASEESSYILDAVAGTEKGPGEEPRHEEKQMEGSDGIGDVLSHLRKQVEMLFNTRYAKAIGISEPVKVPYSKFLMYPEDLFVVGLPEGILLRRPNCFGIAKLKKILQASNNIQFVIKRPELLAEGIKEMALDSPGAKAASDCGDALLDDAVKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPAPRRITSLEKAYAALNDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPIMVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARESIRMVIINQLQPFSEICTEAKPTEKDSSVPKRKRKRISEGNSVSSSSSSSSSSSSNMESTSSTNQISLVQWPMNMYMLDYGGLNVQIPGPINY", "length": 971, "header": "tr|A0A8V1AHZ4-1|A0A8V1AHZ4_CHICK Isoform 1 of General transcription factor II-I repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GTF2IRD1 PE=4 SV=1 CANONICAL=A0A8V1AHZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4/entry#A0A8V1ACN7-1", "sequence": { "sequence": "MALAGRPLDVTLGSSRPEQWNMVFPQKDEIITSLVSALDSMCSALSKLNAEVACIAVHDENTFVLGTEKGRVFLSARKELQADFQKFCREAVGKSSVVPLPYERFLKEPGLLAVAGLPEGISFKKPMEYDVKSLMAILEHSHSIRFRLKRPADEPSREPNPSVELTCTSLVPKGGRDPGANSHTAKPSGQDAPPAVAVTNFLYGVSLPTQIAMDLKQEVSSGLHGATVASEVLLPRPSGELKVPSSQEYSDCCGQKSAVSGGPLIQNVHSSKRILFSIVHDKTDKWDSFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHNIHFVIKRMFDERIFTGSKFTKDPTKLEPSSPPGEISPEPHRGAVLDLAGTSQAASRSEKCSLPESCEPGTSGELGGIRQIKIEPDELDIIQITVPDRSPGSDEMHDPATTHVASEESSYILDAVAGTEKGPGEEPRHEEKQMEGSDGIGDVLSHLRKQVEMLFNTRYAKAIGISEPVKVPYSKFLMYPEDLFVVGLPEGILLRRPNCFGIAKLKKILQASNNIQFVIKRPELLAEGIKEMALDSPGAKAASDCGDALLDDAVKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPAPRRITSLEKAYAALNDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPIMVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARESIRMVIINQLQPFSEICTEAKPTEKDSSVPKRKRKRISEGNSVSSSSSSSSSSSSNMESTSSTNQISLVQWPMNMYMLDYGGLNVQIPGPINY", "length": 922, "header": "tr|A0A8V1ACN7-1|A0A8V1ACN7_CHICK Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GTF2IRD1 PE=4 SV=1 CANONICAL=A0A8V1AHZ4-1" }, "locus": { "chromosome": "19", "start_pos": 3238893, "end_pos": 3204124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071064.1", "url": "https://www.ensembl.org/id/ENSGALT00010071064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043755.1", "url": "https://www.ensembl.org/id/ENSGALP00010043755.1" } ] } }, { "isoform_ac": "A0A8V1AHZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4/entry#A0A8V1AHZ4-1", "sequence": { "sequence": "MALAGRPLDVTLGSSRPEQWNMVFPQKDEIITSLVSALDSMCSALSKLNAEVACIAVHDENTFVLGTEKGRVFLSARKELQADFQKFCRVQQRREQDAEAQKKAKECGRSVLRVSPDQGSDVYLLRKMVEEVFDVLYSEAVGKSSVVPLPYERFLKEPGLLAVAGLPEGISFKKPMEYDVKSLMAILEHSHSIRFRLKRPADEPSREPNPSVELTCTSLVPKGGRDPGANSHTAKPSGQDAPPAVAVTNFLYGVSLPTQIAMDLKQEVSSGLHGATVASEVLLPRPSGELKVPSSQEYSDCCGQKSAVSGGPLIQNVHSSKRILFSIVHDKTDKWDSFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHNIHFVIKRMFDERIFTGSKFTKDPTKLEPSSPPGEISPEPHRGAVLDLAGTSQAASRSEKCSLPESCEPGTSGELGGIRQIKIEPDELDIIQITVPDRSPGSDEMHDPATTHVASEESSYILDAVAGTEKGPGEEPRHEEKQMEGSDGIGDVLSHLRKQVEMLFNTRYAKAIGISEPVKVPYSKFLMYPEDLFVVGLPEGILLRRPNCFGIAKLKKILQASNNIQFVIKRPELLAEGIKEMALDSPGAKAASDCGDALLDDAVKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPAPRRITSLEKAYAALNDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPIMVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARESIRMVIINQLQPFSEICTEAKPTEKDSSVPKRKRKRISEGNSVSSSSSSSSSSSSNMESTSSTNQISLVQWPMNMYMLDYGGLNVQIPGPINY", "length": 971, "header": "tr|A0A8V1AHZ4-1|A0A8V1AHZ4_CHICK Isoform 1 of General transcription factor II-I repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GTF2IRD1 PE=4 SV=1 CANONICAL=A0A8V1AHZ4-1" }, "locus": { "chromosome": "19", "start_pos": 3238893, "end_pos": 3204124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071066.1", "url": "https://www.ensembl.org/id/ENSGALT00010071066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043757.1", "url": "https://www.ensembl.org/id/ENSGALP00010043757.1" } ] } }, { "isoform_ac": "A0A8V1AJY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4/entry#A0A8V1AJY0-1", "sequence": { "sequence": "MALAGRPLDVTLGSSRPEQWNMVFPQKDEIITSLVSALDSMCSALSKLNAEVACIAVHDENTFVLGTEKGRVFLSARKELQADFQKFCRVQQRREQDAEAQKKAKECGRSVLRVSPDQGSDVYLLRKMVEEVFDVLYSEAVGKSSVVPLPYERFLKEPGLLAVAGLPEGISFKKPMEYDVKSLMAILEHSHSIRFRLKRPADEPSREPNPSVELTCTSLVPKGGRDPGANSHTAKPSGQDAPPAVAVTNFLYGVSLPTQIAMDLKQEVSSGLHGATVASEVLLPRPSGELKVPSSQEYSDCCGQKSAVSGGPLIQNVHSSKRILFSIVHDKTDKWDSFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHNIHFVIKRMFDERIFTGSKFTKDPTKLEPSSPPGEISPEPHRGAVLDLAGTSQAASRSEKCSLPESCEPGTSGELGGIRQIKIEPDELDIIQITVPDRSPGSDEMHDPATTHVASEESSYILDAVAGTEKGPGEEPRHEEKQMEGSDGIGDVLSHLRKQVEMLFNTRYAKAIGISEPVKVPYSKFLMYPEDLFVVGLPEGILLRRPNCFGIAKLKKILQASNNIQFVIKRPELLAEGIKEMALDSPGAKAASDCGDALLDDAVKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPIMVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARESIRMVIINQLQPFSEICTEAKPTEKDSSVPKRKRKRISEGNSVSSSSSSSSSSSSNMESTSSTNQISLVQWPMNMYMLDYGGLNVQIPGPINY", "length": 955, "header": "tr|A0A8V1AJY0-1|A0A8V1AJY0_CHICK Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GTF2IRD1 PE=4 SV=1 CANONICAL=A0A8V1AHZ4-1" }, "locus": { "chromosome": "19", "start_pos": 3238893, "end_pos": 3204124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071063.1", "url": "https://www.ensembl.org/id/ENSGALT00010071063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043754.1", "url": "https://www.ensembl.org/id/ENSGALP00010043754.1" } ] } }, { "isoform_ac": "A0A8V1ALY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4/entry#A0A8V1ALY8-1", "sequence": { "sequence": "MALAGRPLDVTLGSSRPEQWNMVFPQKDEIITSLVSALDSMCSALSKLNAEVACIAVHDENTFVLGTEKGRVFLSARKELQADFQKFCRVQQRREQDAEAQKKAKECGRSVLRVSPDQGSDVYLLRKMVEEVFDVLYSEAVGKSSVVPLPYERFLKEPGLLAVAGLPEGISFKKPMEYDVKSLMAILEHSHSIRFRLKRPADEPSREPNPSVELTCTSLVPKGGRDPGANSHTAKPSGQDAPPAVAVTNFLYGVSLPTQIAMDLKQEVSSGLHGATVASEVLLPRPSGELKVPSSQEYSDCCGQKSAVSGGPLIQNVHSSKRILFSIVHDKTDKWDSFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHNIHFVIKRMFDERIFTGSKFTKDPTKLEPSSPPGEISPEPHRGAVLDLAGTSQAASRSEKCSLPESCEPGTSGELGGIRQIKIEPDELDIIQITVPDRSPGSDEMHDPATTHVASEESSYILDAVAGTEKGPGEEPRHEEKQMEGSDGIGDVLSHLRKQVEMLFNTRYAKAIGISEPVKVPYSKFLMYPEDLFVVGLPEGILLRRPNCFGIAKLKKILQASNNIQFVIKRPELLAEGIKEMALDSPGAKENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPAPRRITSLEKAYAALNDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPIMVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARESIRMVIINQLQPFSEICTEAKPTEKDSSVPKRKRKRISEGNSVSSSSSSSSSSSSNMESTSSTNQISLVQWPMNMYMLDYGGLNVQIPGPINY", "length": 951, "header": "tr|A0A8V1ALY8-1|A0A8V1ALY8_CHICK Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GTF2IRD1 PE=4 SV=1 CANONICAL=A0A8V1AHZ4-1" }, "locus": { "chromosome": "19", "start_pos": 3238893, "end_pos": 3204124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071067.1", "url": "https://www.ensembl.org/id/ENSGALT00010071067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043758.1", "url": "https://www.ensembl.org/id/ENSGALP00010043758.1" } ] } }, { "isoform_ac": "A0A8V1ANH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4/entry#A0A8V1ANH8-1", "sequence": { "sequence": "MALAGRPLDVTLGSSRPEQWNMVFPQKDEIITSLVSALDSMCSALSKLNAEVACIAVHDENTFVLGTEKGRVFLSARKELQADFQKFCRVQQRREQDAEAQKKAKECGRSVLRVSPDQGSDVYLLRKMVEEVFDVLYSEAVGKSSVVPLPYERFLKEPGLLAVAGLPEGISFKKPMEYDVKSLMAILEHSHSIRFRLKRPADEPSREPNPSVELTCTSLVPKGGRDPGANSHTAKPSGQDAPPAVAVTNFLYGVSLPTQIAMDLKQEVSSGLHGATVASEVLLPRPSGELKVPSSQEYSDCCGQKSAVSGGPLIQNVHSSKRILFSIVHDKTDKWDSFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHNIHFVIKRMFDERIFTGSKFTKDPTKLEPSSPPGEISPEPHRGAVLDLAGTSQAASRSEKCSLPESCEPDRSPGSDEMHDPATTHVASEESSYILDAVAGTEKGPGEEPRHEEKQMEGSDGIGDVLSHLRKQVEMLFNTRYAKAIGISEPVKVPYSKFLMYPEDLFVVGLPEGILLRRPNCFGIAKLKKILQASNNIQFVIKRPELLAEGIKEMALDSPGAKAASDCGDALLDDAVKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPIMVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARESIRMVIINQLQPFSEICTEAKPTEKDSSVPKRKRKRISEGNSVSSSSSSSSSSSSNMESTSSTNQISLVQWPMNMYMLDYGGLNVQIPGPINY", "length": 928, "header": "tr|A0A8V1ANH8-1|A0A8V1ANH8_CHICK Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 OS=Gallus gallus OX=9031 GN=GTF2IRD1 PE=4 SV=1 CANONICAL=A0A8V1AHZ4-1" }, "locus": { "chromosome": "19", "start_pos": 3238893, "end_pos": 3204124, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071065.1", "url": "https://www.ensembl.org/id/ENSGALT00010071065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043756.1", "url": "https://www.ensembl.org/id/ENSGALP00010043756.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417487", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI04-1", "uniprot_ac": "A0A8V1AI04", "uniprot_id": "A0A8V1AI04_CHICK", "mass": { "chemical_mass": 118350.0, "monoisotopic_mass": 118350.0 }, "refseq": {}, "gene_names": [ { "name": "INTS3", "type": "recommended", "evidence": [ { "id": "A0A8V1AI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04", "locus": { "chromosome": "25", "start_pos": 1805836, "end_pos": 1773431, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028197", "url": "https://www.ensembl.org/id/ENSGALG00010028197" } ] } } ], "crossref": [ { "id": "A0A8V1AI04", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AI04", "database": "AlphaFoldDB", "categories": [] }, { "id": "771890", "url": "https://www.ncbi.nlm.nih.gov/gene/771890", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771890", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771890", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FEQYCLW", "url": "https://omabrowser.org/oma/group/FEQYCLW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7Z8", "url": "https://www.orthodb.org/?gene=A0A8V1A7Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI04", "url": "https://www.orthodb.org/?gene=A0A8V1AI04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJV8", "url": "https://www.orthodb.org/?gene=A0A8V1AJV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13587:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13587:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMQKGKGGAAGGGGGKLLLSTLLDAKDELEERLERCVGIVTSLTNGLSEREANDALNAHICKGTPQHEEICLGLFTLVLTEPTQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLMWLLRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAENVLEILTEQREWVLKSSLLIAMAVYTYLRLIVDHHGTAPLQALRQKEVDFCISLLRERFMDCFMIGRDLVRLLQNVARIPEFEQLWKDIIHNPQVLSTQFTGVLQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRLYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTPWLCCALDPLGSAFPASPSSSSRPFALRAVQILDASKSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEAHVRQGVFNSLTHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPIEVKIEEPVSMEMDNHMSDKDDSCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETIVEEPVDITPFLDQLDESLKDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSGFSLLLDLLSELYQKQPKIGYHLLYYLKASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCTWQLFLAHSIPLEAIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWGLKHDDLLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDSLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSSKPPHSVFPPISPPPPPRRHRCADFQTRDVNKGVSTKGWG", "length": 1039, "header": "tr|A0A8V1AI04-1|A0A8V1AI04_CHICK Isoform 1 of Integrator complex subunit 3 OS=Gallus gallus OX=9031 GN=INTS3 PE=1 SV=1 CANONICAL=A0A8V1AI04-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04/entry#A0A8V1A7Z8-1", "sequence": { "sequence": "MSPRCEVCAGATVTKICKGTPQHEEICLGLFTLVLTEPTQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLMWLLRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAENVLEILTEQREWVLKSSLLIAMAVYTYLRLIVDHHGTAPLQALRQKEVDFCISLLRERFMDCFMIGRDLVRLLQNVARIPEFEQLWKDIIHNPQVLSTQFTGVLQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRLYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEAHVRQGVFNSLTHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPIEVKIEEPVSMEMDNHMSDKDDSCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETIVEEPVDITPFLDQLDESLKDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSGFSLLLDLLSELYQKQPKIGYHLLYYLKASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCTWQLFLAHSIPLEAIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWGLKHDDLLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDSLRLNLANTKQNCSAISSPWLRNTRTRPANPPRAAGRPPSPAPAAARALRSPPTTRRSRRPAAPRRRRTPNPNPQSGSGRAPPPWVRTATEAQRGRAAPTARRSAPIATAPPGGGGGNCTCVSPPHSVFPPISPPPPPRRHRCADFQTRDVNKGVSTKGWG", "length": 1026, "header": "tr|A0A8V1A7Z8-1|A0A8V1A7Z8_CHICK Computationally mapped isoform of Integrator complex subunit 3 OS=Gallus gallus OX=9031 GN=INTS3 PE=1 SV=1 CANONICAL=A0A8V1AI04-1" }, "locus": { "chromosome": "25", "start_pos": 1805719, "end_pos": 1777212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068333.1", "url": "https://www.ensembl.org/id/ENSGALT00010068333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042076.1", "url": "https://www.ensembl.org/id/ENSGALP00010042076.1" } ] } }, { "isoform_ac": "A0A8V1AI04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04/entry#A0A8V1AI04-1", "sequence": { "sequence": "MEMQKGKGGAAGGGGGKLLLSTLLDAKDELEERLERCVGIVTSLTNGLSEREANDALNAHICKGTPQHEEICLGLFTLVLTEPTQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLMWLLRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAENVLEILTEQREWVLKSSLLIAMAVYTYLRLIVDHHGTAPLQALRQKEVDFCISLLRERFMDCFMIGRDLVRLLQNVARIPEFEQLWKDIIHNPQVLSTQFTGVLQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRLYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTPWLCCALDPLGSAFPASPSSSSRPFALRAVQILDASKSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEAHVRQGVFNSLTHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPIEVKIEEPVSMEMDNHMSDKDDSCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETIVEEPVDITPFLDQLDESLKDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSGFSLLLDLLSELYQKQPKIGYHLLYYLKASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCTWQLFLAHSIPLEAIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWGLKHDDLLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDSLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSSKPPHSVFPPISPPPPPRRHRCADFQTRDVNKGVSTKGWG", "length": 1039, "header": "tr|A0A8V1AI04-1|A0A8V1AI04_CHICK Isoform 1 of Integrator complex subunit 3 OS=Gallus gallus OX=9031 GN=INTS3 PE=1 SV=1 CANONICAL=A0A8V1AI04-1" }, "locus": { "chromosome": "25", "start_pos": 1805719, "end_pos": 1773954, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068336.1", "url": "https://www.ensembl.org/id/ENSGALT00010068336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042079.1", "url": "https://www.ensembl.org/id/ENSGALP00010042079.1" } ] } }, { "isoform_ac": "A0A8V1AJV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI04/entry#A0A8V1AJV8-1", "sequence": { "sequence": "MEMQKGKGGAAGGGGGKLLLSTLLDAKDELEERLERCVGIVTSLTNGLSEREANDALNAHICKGTPQHEEICLGLFTLVLTEPTQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLMWLLRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAENVLEILTEQREWVLKSSLLIAMAVYTYLRLIVDHHGTAPLQALRQKEVDFCISLLRERFMDCFMIGRDLVRLLQNVARIPEFEQLWKDIIHNPQVLSTQFTGVLQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRLYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEAHVRQGVFNSLTHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPIEVKIEEPVSMEMDNHMSDKDDSCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETIVEEPVDITPFLDQLDESLKDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSGFSLLLDLLSELYQKQPKIGYHLLYYLKASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCYLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCTWQLFLAHSIPLEAIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWGLKHDDLLAEHIKALLIKNNSLPRKRQRTNGRSRSAPSLRSSSSKLAQLTLEQILEHLDSLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSSKPPKSRRKAALASPRSRKSAAQPPNNEEESASSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1034, "header": "tr|A0A8V1AJV8-1|A0A8V1AJV8_CHICK Computationally mapped isoform of Integrator complex subunit 3 OS=Gallus gallus OX=9031 GN=INTS3 PE=1 SV=1 CANONICAL=A0A8V1AI04-1" }, "locus": { "chromosome": "25", "start_pos": 1805419, "end_pos": 1773954, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068339.1", "url": "https://www.ensembl.org/id/ENSGALT00010068339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042082.1", "url": "https://www.ensembl.org/id/ENSGALP00010042082.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771890", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771890", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7F730-1", "protein_name": "Integrator complex subunit 3 isoform X1", "gene_name": "Ints3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MELQKGKGTVAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTTGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDVTPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEMREDFDSEQLSVLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNTAQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1043 }, "evidence": [ { "id": "A0A8V1AI04", "url": "https://omabrowser.org/oma/group/A0A8V1AI04/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZUT9-1", "protein_name": "Integrator complex subunit 3", "gene_name": "Ints3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELQKGKGTVAAASSGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRSMLREKFPEFCSSPSPPVEASFPEASGILGSTRGYQESFFLYSQVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDVTPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETVIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNAAQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1066 }, "evidence": [ { "id": "A0A8V1AI04", "url": "https://omabrowser.org/oma/group/A0A8V1AI04/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BN70-1", "protein_name": "Integrator complex subunit 3", "gene_name": "INTS3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELQKGKGAAAAAASGAAGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTTGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILMEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMVGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKGHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1040 }, "evidence": [ { "id": "A0A8V1AI04", "url": "https://omabrowser.org/oma/group/A0A8V1AI04/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SFW4-1", "protein_name": "Integrator complex subunit 3", "gene_name": "INTS3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELQKGKGAAAAAASGAAGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTTGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTTPLLALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFEQLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNAAQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1040 }, "evidence": [ { "id": "A0A8V1AI04", "url": "https://omabrowser.org/oma/group/A0A8V1AI04/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LXC9-1", "protein_name": "Integrator complex subunit 3", "gene_name": "ints3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPSPAKGKAQGRLLVSTSLDAKDELEERLERCMSITTSITNGLSEREANDALTAHVCKGPQQHEEVCLGLFTLLLTEPPQAQRCYRDLTLVNRDGMNVVLMKINQILMEKFLKLQDVCRTQLVWLVRELVKSGVIGADGVLMTLMKQIAGGDISSKNLWLAENVLDILVDQREWVLKSGMLVAMSLYTYLRLIVDHGTTSLLPLRQREVDFCIGLLRERFMECFIIGRDLVRLLQNVARIPEMELVWRDLLHSPQTLSPQFTGILQLLTSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTAESQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFNPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPHFFPPLEGQVRQGVFNSLNFIMEKRVLAHLAPLFDNPKLDRELRSMLRERFPEFCSSPSPPTEVKMEESVPLEMDNHVLDKEDGCYDNTDATFSDDEEELNNKGKKREFRFHQLKETYIDEPSDITPFVDQLDEALKERVLQLQKGSDTETHCEVMQEIVDLILEEDFDSEQMSTLASCLAELFKSHFRGDVLPEEITEESLEESVCKPVCLIFRNLCQMQEDNSGFSVLLDLLAELYQKQPKIGYHLLYYLKASKAASGKMSLYESFAQATALGDLHTCLMMDMKACQEDDVRLLCYLTPSIYSEFPDETLRSGELLNMIVAVIDSAQLQELMCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYSTWQLFLAHSIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPYHQEDQFTTSILRHWTAKHDDLLGEHIKALLIKNNNMPRKRQSLRSSSSKLAQLTLEQMLEHLDSLRLSLSNTKNNFFSQTPILQALQHVQASCDEAHKMRFSDLFSLAEEYEDSSKPPKSRRKAPASSPRSRKGAAPQPCNEEESVSSSASEEEDSKPKASKRKRKGSAVGSDSD", "length": 1017 }, "evidence": [ { "id": "A0A8V1AI04", "url": "https://omabrowser.org/oma/group/A0A8V1AI04/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q68E01-1", "protein_name": "Integrator complex subunit 3", "gene_name": "INTS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELQKGKGAAAAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGLPQHEEICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", "length": 1043 }, "evidence": [ { "id": "A0A8V1AI04", "url": "https://omabrowser.org/oma/group/A0A8V1AI04/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7PLS8-1", "protein_name": "Integrator complex subunit 3", "gene_name": "IntS3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEQQQSKNNAHVSKLFICTAVDCKDDIEEKFERSFVTLQMQISGLSDKEMHDMLSQAVCKEKQHEEISIGFLYIMLTDPSMASKTYRDVTLVSRDGMNGIVTNLTFLVAEKYTKLTEVARRQLIWLLREFVKHQVLSVENVIWNCLRQAGGGDVSSRNLFLIESLLDIFIEFRTWLETNPFLVQSTVYSFVRLIEDHANPALLSLRQKEVKFTISLIRERFHDIIPLGRDFVRLLQNVARIPEFEQLWRDILFNPKMLHQTFNGIWQLLHIRTSRRFLQCRLLPEMERKISFLASSVKFGNQKRYQDWFQDKYFATPESHSLRSDLIRFIINVIHPTNDMLCSDIIPRWAIIGWLISSCTNPIASANAKLSLFYDWLFFDPAKDNIMNIEPGILVMYHSIRNHPFVSSTLLDFLCRITKNFFVKHEDKIRIGVYNSLKLILEKQVIPNLQPLFESPKLDRELRNLIRDNFREFLSPPANHGQLLFTSLHPVQGHILKKESDQRILHCENMDLHETGLINISGTIDEDKKILLVPTDQEIESVFSDETAENLRRVHNIEDNTDDDDDLPLSEVRLKEKPKVELAEAIAESFDAFVTKRNSYTWEAFLKDFRPLPASAFEEFQLNYVISNTVLILRETLPQQNIFSESKTEEKHLAKSISYPLYGLFRFLYENDEKSKKPFQTLLSEICEGIPEIGYLLLYFMKIYCKLQTRKNSQQSYQFKTTIYRQICDAADEKIGNCLLRDLDLLEKENTNIFLWLLPDIYREFKSIATNNTDLLRITLRCIDAKNVRDILYSIAQGKLTIFKQDGLIDCIRQSLEFETYEQFCLWQIVQAHDVPLRCIQDILPELEAGSHPEALSHFLLLLKNEEPTNEIIRLMLSRESKSKGDPFVTSALRFWCQRYEEKLSEIIASLLTSKYPSSSPNKRKRPPKGISVSTSTPSADQVLNHLEHYRRSCRHGTGTGLYVHDMMQRALQSAYSHSNDSTKKQFCDLFALAAEEDTTVGRRGGSGRGRKQPGSKKDVNNHGTSKKNPEMVKTIYSSDDNSSEEDWSKSKILQTAKRRKKANNDSD", "length": 1068 }, "evidence": [ { "id": "A0A8V1AI04", "url": "https://omabrowser.org/oma/group/A0A8V1AI04/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7TPD0-1", "protein_name": "Integrator complex subunit 3", "gene_name": "Ints3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELQKGKGTVAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQAQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKLALFYDWLFFSPEKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRSMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDVTPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEHIKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD", 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"MGSCGRRNFGMEPGLRMAFIHLIAGLMSSPAPGGLPGLDKTSEMRESALGVLVEHTGSWKSPAGYFSRWLDRISKGWPSLLGAVAALVLLAQEARRLTLGQR", "length": 102, "header": "tr|A0A8V1AI11-1|A0A8V1AI11_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AI11-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AI11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI11/entry#A0A8V1AI11-1", "sequence": { "sequence": "MGSCGRRNFGMEPGLRMAFIHLIAGLMSSPAPGGLPGLDKTSEMRESALGVLVEHTGSWKSPAGYFSRWLDRISKGWPSLLGAVAALVLLAQEARRLTLGQR", "length": 102, "header": "tr|A0A8V1AI11-1|A0A8V1AI11_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AI11-1" }, "locus": { "chromosome": "12", "start_pos": 3440047, "end_pos": 3439742, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068346.1", "url": "https://www.ensembl.org/id/ENSGALT00010068346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042089.1", "url": "https://www.ensembl.org/id/ENSGALP00010042089.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI21-1", "uniprot_ac": "A0A8V1AI21", "uniprot_id": "A0A8V1AI21_CHICK", "mass": { "chemical_mass": 99065.0, "monoisotopic_mass": 99065.0 }, "refseq": { "ac": "XP_427028", "name": "whirlin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427028" }, "gene_names": [ { "name": "WHRN", "type": "recommended", "evidence": [ { "id": "A0A8V1AI21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ] }, { "name": "WHRN", "type": "synonym", "evidence": [ { "id": "XP_427028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427028" } ] } ], "protein_names": [ { "name": "Whirlin", "type": "recommended", "evidence": [ { "id": "A0A8V1AI21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21/entry#names_and_taxonomy" } ] }, { "name": "whirlin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_427028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427028" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_427028.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_427028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427028" } ] }, { "annotation": "Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21#function" }, { "database": "UniProtKB", "id": "ARBA00053543", "url": "https://www.uniprot.org/uniprotkb/ARBA00053543#function" }, { "database": "UniProtKB", "id": "A0A8V1AAM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAM7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WHRN", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21", "locus": { "chromosome": "17", "start_pos": 3138781, "end_pos": 3165940, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028895", "url": "https://www.ensembl.org/id/ENSGALG00010028895" } ] } } ], "crossref": [ { "id": "A0A8V1AI21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AI21", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06740", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06740", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06742", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06742", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07357", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07357", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429472", "url": "https://www.ncbi.nlm.nih.gov/gene/429472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429472", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TMVNQTR", "url": "https://omabrowser.org/oma/group/TMVNQTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAM7", "url": "https://www.orthodb.org/?gene=A0A8V1AAM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI21", "url": "https://www.orthodb.org/?gene=A0A8V1AI21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23116:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23116:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_427028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAEPDGVSLRSSSSSSGSLGSAAGPALRPLSANVRRLHQALTALLSEAERERFILCLNAYHGRRNVCDLVRSLRALLDGPRRRQLLPLLRLVLPRSDQLLFDQYTAEGPYLPPPGRPPPPPGELRQVTLRRSKAHEGLGFSIRGGAEHGVGIYVSLVEPGSLAEREGLRVGDQILGVNGKPLDRVTHAEAVKVLKGCKKLNLSVHSVGRIPGGYVTNHIYTWVDPQGRSVSPPTGLPHHQNSSLRKDGEKRSHLQLLQEGDEKKVNLVLNEGKSLGLMIRGGAEYSLGIYITGVDKGSEAESTGLKVGDQILEVNGRSFLSIPHDEAVKLLKSSRHLIMTVKDIGRLPHARTTVDETRWIASSQIGETLVSSTGVVGDHAAEATARPLFYRGLAGSQVTLSSMVNQTRVMLEEQARHLLNEQERATMGYYLDEYKEGHISVDALVMALFELLNTHAKFSLLSEVRGVISPQDLDRFDNLVLKREIESMKARQPAGPSVGTDSYSMMSYSDTISSSSSHFTSTTVSSARERLLWLIDLMENTSELEGGEDCQQSSINTLPDISLDDLSSFPEEPPNFKPPPPPTAPQMLDPSAAQHRNPGKDKPKRPSSESSQSGLFFVAPRNPTPPPSHSEKDTISVASTATTSTEESSPSAIYATISPAPRGSRRQMDPQLSLLSHPPIGPFPRVQSPTRLTSPPTDGPAAAGCQSPASPSPPPPPAHPAPPPPSPQANQHFIMVEVHQPNSEPDVNEVRPLPQARASTLSQLSDSGQTLSEDSGVDIGEVEVSSKDKSRQPVLGKSRSLKEGTRSEGTAEGASKPPGLLEPTSCLIRVSKSAPTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGTGLRGKEHREAARIIAEAFKLKEKDYIDFLVTEFNVAL", "length": 919, "header": "tr|A0A8V1AI21-1|A0A8V1AI21_CHICK Isoform 1 of Whirlin OS=Gallus gallus OX=9031 GN=WHRN PE=4 SV=1 CANONICAL=A0A8V1AI21-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21/entry#A0A8V1AAM7-1", "sequence": { "sequence": "MSAEPDGVSLRSSSSSSGSLGSAAGPALRPLSANVRRLHQALTALLSEAERERFILCLNAYHGRRNVCDLVRSLRALLDGPRRRQLLPLLRLVLPRSDQLLFDQYTAEGPYLPPPGRPPPPPGELRQVTLRRSKAHEGLGFSIRGGAEHGVGIYVSLVEPGSLAEREGLRVGDQILGVNGKPLDRVTHAEAVKVLKGCKKLNLSVHSVGRIPGGYVTNHIYTWVDPQGRSVSPPTGLPHHQNSSLRKDGEKRSHLQLLQEGDEKKVNLVLNEGKSLGLMIRGGAEYSLGIYITGVDKGSEAESTGLKVGDQILEVNGRSFLSIPHDEAVKLLKSSRHLIMTVKDIGRLPHARTTVDETRWIASSQIGETLVSSTGVVGDHAAEATARPLFYRGLAGSQVTLSSMVNQTRVMLEEQARHLLNEQERATMGYYLDEYKEGHISVDALVMALFELLNTHAKFSLLSEVRGVISPQDLDRFDNLVLKREIESMKARQPAGPSVGTDSYSMMSYSDTISSSSSHFTSTTVSSARNTSELEGGEDCQQSSINTLPDISLDDLSSFPEEPPNFKPPPPPTAPQMLDPSAAQHRNPGKDKPKRPSSESSQSGLFFVAPRNPTPPPSHSEKDTISVASTATTSTEESSPSAIYATISPAPRGSRRQMDPQLSLLSHPPIGPFPRVQSPTRLTSPPTDGPAAAGCQSPASPSPPPPPAHPAPPPPSPQANQHFIMVEVHQPNSEPDVNEVRPLPQARASTLSQLSDSGQTLSEDSGVDIGEVEVSSKDKSRQPVLGKSRSLKEGTRSEGTAEGASKPPGLLEPTSCLIRVSKSAPTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGTGLRGKEHREAARIIAEAFKLKEKDYIDFLVTEFNVAL", "length": 908, "header": "tr|A0A8V1AAM7-1|A0A8V1AAM7_CHICK Computationally mapped isoform of Whirlin OS=Gallus gallus OX=9031 GN=WHRN PE=4 SV=1 CANONICAL=A0A8V1AI21-1" }, "locus": { "chromosome": "17", "start_pos": 3165815, "end_pos": 3139310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069908.1", "url": "https://www.ensembl.org/id/ENSGALT00010069908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043034.1", "url": "https://www.ensembl.org/id/ENSGALP00010043034.1" } ] } }, { "isoform_ac": "A0A8V1AI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21/entry#A0A8V1AI21-1", "sequence": { "sequence": "MSAEPDGVSLRSSSSSSGSLGSAAGPALRPLSANVRRLHQALTALLSEAERERFILCLNAYHGRRNVCDLVRSLRALLDGPRRRQLLPLLRLVLPRSDQLLFDQYTAEGPYLPPPGRPPPPPGELRQVTLRRSKAHEGLGFSIRGGAEHGVGIYVSLVEPGSLAEREGLRVGDQILGVNGKPLDRVTHAEAVKVLKGCKKLNLSVHSVGRIPGGYVTNHIYTWVDPQGRSVSPPTGLPHHQNSSLRKDGEKRSHLQLLQEGDEKKVNLVLNEGKSLGLMIRGGAEYSLGIYITGVDKGSEAESTGLKVGDQILEVNGRSFLSIPHDEAVKLLKSSRHLIMTVKDIGRLPHARTTVDETRWIASSQIGETLVSSTGVVGDHAAEATARPLFYRGLAGSQVTLSSMVNQTRVMLEEQARHLLNEQERATMGYYLDEYKEGHISVDALVMALFELLNTHAKFSLLSEVRGVISPQDLDRFDNLVLKREIESMKARQPAGPSVGTDSYSMMSYSDTISSSSSHFTSTTVSSARERLLWLIDLMENTSELEGGEDCQQSSINTLPDISLDDLSSFPEEPPNFKPPPPPTAPQMLDPSAAQHRNPGKDKPKRPSSESSQSGLFFVAPRNPTPPPSHSEKDTISVASTATTSTEESSPSAIYATISPAPRGSRRQMDPQLSLLSHPPIGPFPRVQSPTRLTSPPTDGPAAAGCQSPASPSPPPPPAHPAPPPPSPQANQHFIMVEVHQPNSEPDVNEVRPLPQARASTLSQLSDSGQTLSEDSGVDIGEVEVSSKDKSRQPVLGKSRSLKEGTRSEGTAEGASKPPGLLEPTSCLIRVSKSAPTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGTGLRGKEHREAARIIAEAFKLKEKDYIDFLVTEFNVAL", "length": 919, "header": "tr|A0A8V1AI21-1|A0A8V1AI21_CHICK Isoform 1 of Whirlin OS=Gallus gallus OX=9031 GN=WHRN PE=4 SV=1 CANONICAL=A0A8V1AI21-1" }, "locus": { "chromosome": "17", "start_pos": 3165815, "end_pos": 3139310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069907.1", "url": "https://www.ensembl.org/id/ENSGALT00010069907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043033.1", "url": "https://www.ensembl.org/id/ENSGALP00010043033.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 584, "start_aa": "Thr", "end_pos": 584, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr584", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:429472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429472", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LPJ0-1", "protein_name": "Whirlin", "gene_name": "WHRN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNAQLDGLSVGSSSTGSLGSAAGAGGSGGAGLRLLSANVRQLHQALTALLSEAEREQFTHCLNAYHARRNVFDLVRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPVWGGPDGAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSISPPSGLPQPHGSALRQHEGDRRSTLHLLQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYVTGVDPGSEAESSGLKVGDQILEVNGRSFLNILHDEAVRLLKSSQHLILTVKDIGRLPHARTTVDQTEWIASSRIGDAAASCARFPGDLTAEGTNKLGFYKGPAGSQVTLSSLGIQTRVLLEEQARHLLTEQERATMAYYLEEYRGGSVSVEALVMALFELLNTHAKFSLLSEVRGTISPQDLDRFDHLVLRREIESMKARQPPGPAAGDTYSTVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNANTLSDVSLDDVKSTSKGLPSYKPPPPPPPLIQGHDHLLIQPRKPGREDLQPPSSASSHSGIVFSAPQNRSPPAGTAPVPEAPTAQNSPSSPIYASISPANLGSKRPLDTHLALVNQHPIGPFPRVQSPPHLKSPPAEAALAGGGLPPPSPSGHPDQAGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGEAEASVPGRGRQTAPTRSRSGKETPRNERPTEGATKPPGLLEPTSTLIRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGVTLRGKEHREAARIIAEAFKTKERDYIDFLVTEFNVLL", "length": 907 }, "evidence": [ { "id": "A0A8V1AI21", "url": "https://omabrowser.org/oma/group/A0A8V1AI21/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AC58IAF3-1", "protein_name": "Whirlin", "gene_name": "whrna", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTDLERLSLNSSSGNSVASSARSLSANVKKLHNALNLLLSDLEREQFIHCLNVYHSKRNVYDLVQTLKVILNVPSKRQLLPMLRLVIPRSDQLLFDQYTSEGLYLKSEIHARNGDPDGAQEGANSSPTHGANFPASQVALRGSPDSISTSSDGTATLIPLLGRNFLPEPPGEIRQVILKRHKSNEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRMGDQIMKVNDKVFDRVTHADAVKVLKGSKKLCMSVRSVGRIPGGYITNHVYTWVDPQGRSVSPPPDLLAEHRSATLRRSNSQGRSHMQLLQDGDEKKVNLVLDDGRSLGLMIRGGAEYSLGIYITGVDRGSAAECGGIKTVPSPASSRPALPPPAHTPSPVCPPSCPQVGDQILEVNGRSFLSIPHDEAVRVLKSSHHLMMTVKDVGRLPHTRTVVGETKWIASSQISDSSASSSVTGISLDQGASTSAKGGFYKGVAGSQVTLSSLVNQSRAMLEEQARHLLTEPERQTMGYYIQEYRDGHVGVEQLVMALFELFNTHAKFSLLSEVRGIVTPQDVEKFDGLVLRREIDALKARQGGGAGFQDSFSMVSYPDTLASSSASFMTNTTLSSARNDGVAENNGEQGSLEHSNALPDISLDEVHSTSDSPPSFKPPPPPGLQRRPSRKATLSKRPSSSSSQSGLYFTAPSRSHTRESKHPKAPKAFMSPPGTLKIDVPASQLSVVSQHPIGPFPRVQSPNKAKPAQSSSPIPPPAPNVPAPPGPPPPPPPPLPPPSCPDKPTPSSPASNQHFVMVEVHRPNAEPDVNEVRPLPQVRGGTLSQLSDSGQTLSEDSGVDIPESGRLSKDTSPRPARTRAPRDGHGGGETSAKPPGLLEPMSTLVRVAKSASTLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGQVILEVNGVSLRGKEHREAARLIAEAFKTKEKDYIDFLITEFNVAL", "length": 968 }, "evidence": [ { "id": "A0A8V1AI21", "url": "https://omabrowser.org/oma/group/A0A8V1AI21/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80VW5-1", "protein_name": "Whirlin", "gene_name": "Whrn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAQLDGLSVSSSSTGSLGSAAAAAGGGGGAGLRLLSANVRQLHQALTALLSEPEREQFTHCLNAYHARRNVFDLVRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWAAPDGAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSTSPPSSLPQPHGSTLRQREDDRRSTLHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFLNILHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESVANSAGFPGDHTEEGTSKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLAQYRGGTISVEAMVMALFELLNTHAKFSLLSEVRSIISPQDLDRFDHLVLRREIESMKARQPPGPGVGDTYSMVSYSDTGSSTGSHGTSTTVSSARERLLWLIDLMENTLDLEGTGETTQGSTNALPDVSVDDVKSPSEDLPGIKPPPPPPPLAQGHDRLLGQPRKPGREDPAPLSSAAHSGIVFSAPRNRSPPPGTAPTPGPSSAQDSPSSPIYASISHANPSSRKPLDTHLALVNQHPIGPFPRVQSPPHLKSPPAETPGAGACLPPPSPSEHPDAVGANQHFVLVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGETEASTSGRGRQTASAKNKNGKEQPRTERTAEGANKPPGLLEPTSTLVRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAEAFKTKERDYIDFLVTEFNVML", "length": 918 }, "evidence": [ { "id": "A0A8V1AI21", "url": "https://omabrowser.org/oma/group/A0A8V1AI21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q810W9-1", "protein_name": "Whirlin", "gene_name": "Whrn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAQLDGLSVSSSSTGSLGSAAAAAGGGGGAGLRLLSANVRQLHQALTALLSEPEREQFTHCLNAYHARRNVFDLVRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWAAPDGAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSTSPPSSLPHGSTLRQHEDDRRSALHLLQSGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSGLKVGDQILEVNGRSFLSILHDEAVKLLKSSRHLILTVKDVGRLPHARTTVDQTKWIASSRIGESITNSAGFPGDLTEEGTNKPGFYKGPAGSQVTLSSLGNQTRALLDDQARHLLTEQERATMMYYLDQYRGGTISVEALVMALFELLNTHAKFSLLSEVRGIISPQDLDRFDHLVLRREIESMKARQPPGPGVGDTYSMVSYSDTGSSTGSHGTSTTVSSARERLLWLIDLMENTLDLEGTCETTQGSTNALPDVSVDDVRSPSEDLPGIKPPPPPPPLAQGHDRLLGQTRKPVREDSAPLSSAAHSGIVFSAPRNRSPPPPPGIAPTPTPGPSSARDSPSSPIYASISHANPSSRKPLDTHLALVNQHPIGPFPRVQSPPHLKSPPAEAPGAGACLPPPSPSEHADAMGANQHFVLVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGETEASTSGRGRQTANTKNKNGKELPQTERTTEGANKPPGLLEPTSTLIRVRKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHREAARVIAEAFKTKERDYIDFLVTEFNVML", "length": 920 }, "evidence": [ { "id": "A0A8V1AI21", "url": "https://omabrowser.org/oma/group/A0A8V1AI21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P202-1", "protein_name": "Whirlin", "gene_name": "WHRN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNAPLDGLSVSSSSTGSLGSAAGAGGGGGAGLRLLSANVRQLHQALTALLSEAEREQFTHCLNAYHARRNVFDLVRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWGGPDSAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTHAEAVKALKGSKKLVLSVYSAGRIPGGYVTNHIYTWVDPQGRSISPPSGLPQPHGGALRQQEGDRRSTLHLLQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNILHDEAVRLLKSSRHLILTVKDVGRLPHARTTVDETKWIASSRIRETMANSAGFLGDLTTEGINKPGFYKGPAGSQVTLSSLGNQTRVLLEEQARHLLNEQEHATMAYYLDEYRGGSVSVEALVMALFKLLNTHAKFSLLSEVRGTISPQDLERFDHLVLRREIESMKARQPPGPGAGDTYSMVSYSDTGSSTGSHGTSTTVSSARNTLDLEETGEAVQGNINALPDVSVDDVRSTSQGLSSFKPLPRPPPLAQGNDLPLGQPRKLGREDLQPPSSMPSCSGTVFSAPQNRSPPAGTAPTPGTSSAQDLPSSPIYASVSPANPSSKRPLDAHLALVNQHPIGPFPRVQSPPHLKSPSAEATVAGGCLLPPSPSGHPDQTGTNQHFVMVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGEAEASAPGRGRQSVSTKSRSSKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML", "length": 907 }, "evidence": [ { "id": "A0A8V1AI21", "url": "https://omabrowser.org/oma/group/A0A8V1AI21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 14, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "stereocilia ankle link complex", "id": "GO:0002142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002142", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "stereocilium tip", "id": "GO:0032426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "periciliary membrane compartment", "id": "GO:1990075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990075", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "USH2 complex", "id": "GO:1990696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990696", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "detection of mechanical stimulus involved in sensory perception of sound", "id": "GO:0050910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "retina homeostasis", "id": "GO:0001895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "cerebellar Purkinje cell layer formation", "id": "GO:0021694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "auditory receptor cell stereocilium organization", "id": "GO:0060088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060088", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "paranodal junction maintenance", "id": "GO:1990227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" }, { "name": "sensory perception of light stimulus", "id": "GO:0050953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AK96-1", "uniprot_ac": "A0A8V1AK96", "uniprot_id": "A0A8V1AK96_CHICK", "mass": { "chemical_mass": 40921.0, "monoisotopic_mass": 40921.0 }, "refseq": { "ac": "XP_024997292", "name": "transmembrane protein 268 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997292" }, "gene_names": [ { "name": "TMEM268", "type": "recommended", "evidence": [ { "id": "A0A8V1AK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96" } ] }, { "name": "TMEM268", "type": "synonym", "evidence": [ { "id": "XP_024997292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997292" } ] } ], "protein_names": [ { "name": "Transmembrane protein 268", "type": "synonym", "evidence": [ { "id": "A0A8V1AK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 268 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_024997292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997292" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997292.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997292" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK96", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM268", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96", "locus": { "chromosome": "17", "start_pos": 3198582, "end_pos": 3189063, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028897", "url": "https://www.ensembl.org/id/ENSGALG00010028897" } ] } } ], "crossref": [ { "id": "A0A8V1AK96", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AK96", "database": "AlphaFoldDB", "categories": [] }, { "id": "417248", "url": "https://www.ncbi.nlm.nih.gov/gene/417248", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI25", "url": "https://www.orthodb.org/?gene=A0A8V1AI25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK96", "url": "https://www.orthodb.org/?gene=A0A8V1AK96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31193:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31193:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14800", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14800", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997292", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AI25", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK96", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACKSPAGGIEKNSSLSSVLYCKSDLKEGSLQWAKEPRNGQVLMVLSMDNTCSAASFDMELCAEKLQSLGVQAAAGEWRRLIEEAVLKPEVRRYLFYNSRAFQIAIAVVFYMSLWTNIYTTVQLCSFGRYWEASVLVTLAAVAVTVVVILVIDHRQRKINMNTDVRLAAVNEFFIKHSLILGITDVLDGPHSILQLCFVHFSPERCLQSLSAHIAELRQAQELGWRHRLDQLCVMMEVAVPTAEDTSCEESPLLSGGESFKKEPIMCNELLHLIPEGPPEVMAQQLLVIFSACYVRLLVSGRLPRPVATGHMDGSSVPCPCQFIQASVLSTGCCWLPGRGLRGAEGQAQQCEEAEEKSVASHSGLLWKKE", "length": 370, "header": "tr|A0A8V1AK96-1|A0A8V1AK96_CHICK Isoform 1 of Transmembrane protein 268 OS=Gallus gallus OX=9031 GN=TMEM268 PE=4 SV=1 CANONICAL=A0A8V1AK96-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AI25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96/entry#A0A8V1AI25-1", "sequence": { "sequence": "MACKSPAGGIEKNSSLSSVLYCKSDLKEGSLQWAKEPRNGQVLMVLSMDNTCSAASFDMELCAEKLQSLGVQAAAGEWRRLIEEAVLKPEVRRYLFYNSRAFQIAIAVVFYMSLWTNIYTTVQLCSFGRYWEASVLVTLAAVAVTVVVILVIDHRQRKINMNTDVRLAAVNEFFIKHSLILGITDVLDGPHSILQLCFVHFSPERCLQSLSAHIAELRQAQELGWRHRLDQLCVMMEVAVPTAEDTSCEESPLLSGGESFKKEPIMCNELLHLIPEGPPEVMRKPPLWAEHLLGMLSPKLIPVGIAHGVEHLQT", "length": 314, "header": "tr|A0A8V1AI25-1|A0A8V1AK96_CHICK Computationally mapped isoform of Transmembrane protein 268 OS=Gallus gallus OX=9031 GN=TMEM268 PE=4 SV=1 CANONICAL=A0A8V1AK96-1" }, "locus": { "chromosome": "17", "start_pos": 3197578, "end_pos": 3191670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069912.1", "url": "https://www.ensembl.org/id/ENSGALT00010069912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043038.1", "url": "https://www.ensembl.org/id/ENSGALP00010043038.1" } ] } }, { "isoform_ac": "A0A8V1AK96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK96/entry#A0A8V1AK96-1", "sequence": { "sequence": "MACKSPAGGIEKNSSLSSVLYCKSDLKEGSLQWAKEPRNGQVLMVLSMDNTCSAASFDMELCAEKLQSLGVQAAAGEWRRLIEEAVLKPEVRRYLFYNSRAFQIAIAVVFYMSLWTNIYTTVQLCSFGRYWEASVLVTLAAVAVTVVVILVIDHRQRKINMNTDVRLAAVNEFFIKHSLILGITDVLDGPHSILQLCFVHFSPERCLQSLSAHIAELRQAQELGWRHRLDQLCVMMEVAVPTAEDTSCEESPLLSGGESFKKEPIMCNELLHLIPEGPPEVMAQQLLVIFSACYVRLLVSGRLPRPVATGHMDGSSVPCPCQFIQASVLSTGCCWLPGRGLRGAEGQAQQCEEAEEKSVASHSGLLWKKE", "length": 370, "header": "tr|A0A8V1AK96-1|A0A8V1AK96_CHICK Isoform 1 of Transmembrane protein 268 OS=Gallus gallus OX=9031 GN=TMEM268 PE=4 SV=1 CANONICAL=A0A8V1AK96-1" }, "locus": { "chromosome": "17", "start_pos": 3198496, "end_pos": 3191670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069911.1", "url": "https://www.ensembl.org/id/ENSGALT00010069911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043037.1", "url": "https://www.ensembl.org/id/ENSGALP00010043037.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI26-1", "uniprot_ac": "A0A8V1AI26", "uniprot_id": "A0A8V1AI26_CHICK", "mass": { "chemical_mass": 64876.0, "monoisotopic_mass": 64876.0 }, "refseq": { "ac": "XP_024997391", "name": "arylsulfatase G isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997391" }, "gene_names": [ { "name": "ARSG", "type": "recommended", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ] }, { "name": "ARSG", "type": "synonym", "evidence": [ { "id": "XP_024997391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997391" } ] } ], "protein_names": [ { "name": "Arylsulfatase G", "type": "recommended", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.15", "type": "synonym", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#names_and_taxonomy" } ] }, { "name": "3.1.6.1", "type": "synonym", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#names_and_taxonomy" } ] }, { "name": "N-sulfoglucosamine-3-sulfatase", "type": "synonym", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#names_and_taxonomy" } ] }, { "name": "arylsulfatase G isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024997391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997391" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997391.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997391" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARSG", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26", "locus": { "chromosome": "18", "start_pos": 8485687, "end_pos": 8444082, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029391", "url": "https://www.ensembl.org/id/ENSGALG00010029391" } ] } } ], "crossref": [ { "id": "A0A8V1AI26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AI26", "database": "AlphaFoldDB", "categories": [] }, { "id": "771433", "url": "https://www.ncbi.nlm.nih.gov/gene/771433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771433", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HVACRCQ", "url": "https://omabrowser.org/oma/group/HVACRCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI26", "url": "https://www.orthodb.org/?gene=A0A8V1AI26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42693:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42693:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1663150", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024997391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17261", "url": "https://www.rhea-db.org/rhea/17261", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTPAPWSVLLLAVLVGLCTSPVAQGKPNFIVILADDLGWGDLGANWAETKETPHLDELAAEGTRFVDFHSAASTCSPSRASLLTGRLGVRNGVTHNFAISSVGGLPLNETTLAEVLRAAGYSTAAIGKWHLGHHGHHHPIFRGFDYYFGIPYSHDMGCTDTPGYNVPPCPPCPQHSAATSPTNKDCYTDVALPLFENLTIIQQPVDLSSLVEQYMEAAARFIQQARDSSRPFFLYLALAHMHVPLQIAPPPDRGIYGAALREMDALVGHVKHLADSCGKGSTLLWFTGDNGPWMQKCELAGRLGPLLGAWQRAQGGSPAKQTTWEGGHRVPALAYWPGHVPAKRSSHAMLSTLDVFPTLVALAGATLPPNRRFDGMDVSPVLFGLSDVGHKVLLHPNSGAAGKDGAVEALRLAQYKAFYTTGGAKACDGSIGPEEHHRPPLIFNLDRDIQEQEPLDVASREYQAVLPAISRAYAQALEDIATDNTTVADYSKDPAAVPCCSTQHVACRCHAPTSHTASLDQHTDGRATRLCLSDRSLKPLLDESPNCSALRKQRSPVKFRTSKHPNQGSLCTTQREPAPHQRAEQMQNTLLPAMEEKPES", "length": 601, "header": "tr|A0A8V1AI26-1|A0A8V1AI26_CHICK Isoform 1 of Arylsulfatase G OS=Gallus gallus OX=9031 GN=ARSG PE=3 SV=1 CANONICAL=A0A8V1AI26-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AI26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#A0A8V1AI26-1", "sequence": { "sequence": "MGTPAPWSVLLLAVLVGLCTSPVAQGKPNFIVILADDLGWGDLGANWAETKETPHLDELAAEGTRFVDFHSAASTCSPSRASLLTGRLGVRNGVTHNFAISSVGGLPLNETTLAEVLRAAGYSTAAIGKWHLGHHGHHHPIFRGFDYYFGIPYSHDMGCTDTPGYNVPPCPPCPQHSAATSPTNKDCYTDVALPLFENLTIIQQPVDLSSLVEQYMEAAARFIQQARDSSRPFFLYLALAHMHVPLQIAPPPDRGIYGAALREMDALVGHVKHLADSCGKGSTLLWFTGDNGPWMQKCELAGRLGPLLGAWQRAQGGSPAKQTTWEGGHRVPALAYWPGHVPAKRSSHAMLSTLDVFPTLVALAGATLPPNRRFDGMDVSPVLFGLSDVGHKVLLHPNSGAAGKDGAVEALRLAQYKAFYTTGGAKACDGSIGPEEHHRPPLIFNLDRDIQEQEPLDVASREYQAVLPAISRAYAQALEDIATDNTTVADYSKDPAAVPCCSTQHVACRCHAPTSHTASLDQHTDGRATRLCLSDRSLKPLLDESPNCSALRKQRSPVKFRTSKHPNQGSLCTTQREPAPHQRAEQMQNTLLPAMEEKPES", "length": 601, "header": "tr|A0A8V1AI26-1|A0A8V1AI26_CHICK Isoform 1 of Arylsulfatase G OS=Gallus gallus OX=9031 GN=ARSG PE=3 SV=1 CANONICAL=A0A8V1AI26-1" }, "locus": { "chromosome": "18", "start_pos": 8462614, "end_pos": 8444281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071096.1", "url": "https://www.ensembl.org/id/ENSGALT00010071096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043787.1", "url": "https://www.ensembl.org/id/ENSGALP00010043787.1" } ] } }, { "isoform_ac": "A0A8V1AK11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#A0A8V1AK11-1", "sequence": { "sequence": "MGTPAPWSVLLLAVLVGLCTSPVAQGKPNFIVILADDLGWGDLGANWAETKETPHLDELAAEGTRFVDFHSAASTCSPSRASLLTGRLGVRNGVTHNFAISSVGGLPLNETTLAEVLRAAGYSTAAIGKWHLGHHGHHHPIFRGFDYYFGIPYSHDMGCTDTPGYNVPPCPPCPQHSAATSPTNKDCYTDVALPLFENLTIIQQPVDLSSLVEQYMEAAARFIQQARDSSRPFFLYLALAHMHVPLQIAPPPDRGIYGAALREMDALVGHVKHLADSCGKGSTLLWFTGDNGPWMQKCELAGRLGPLLGAWQRAQGGSPAKQTTWEGGHRVPALAYWPGHVPAKRSSHAMLSTLDVFPTLVALAGATLPPNRRFDGMDVSPVLFGLSDVGHKVLLHPNSGAAGKDGAVEALRLAQYKAFYTTGGAKACDGSIGPEEHHRPPLIFNLDRDIQEQEPLDVASREYQAVLPAISRAYAQALEDIATDNTTVADYSKDPAAVPCCSTQHVACRCHAPTSHTASLDQHTDGRATRLCL", "length": 533, "header": "tr|A0A8V1AK11-1|A0A8V1AK11_CHICK Computationally mapped isoform of Arylsulfatase G OS=Gallus gallus OX=9031 GN=ARSG PE=3 SV=1 CANONICAL=A0A8V1AI26-1" }, "locus": { "chromosome": "18", "start_pos": 8459160, "end_pos": 8444281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071093.1", "url": "https://www.ensembl.org/id/ENSGALT00010071093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043784.1", "url": "https://www.ensembl.org/id/ENSGALP00010043784.1" } ] } }, { "isoform_ac": "A0A8V1AM13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#A0A8V1AM13-1", "sequence": { "sequence": "MGTPAPWSVLLLAVLVGLCTSPVAQGKPNFIVILADDLGWGDLGANWAETKETPHLDELAAEGTRFVDFHSAASTCSPSRASLLTGRLGVRNGVTHNFAISSVGGLPLNETTLAEVLRAAGYSTAAIGKWHLGHHGHHHPIFRGFDYYFGIPYSHDMGCTDTPGYNVPPCPPCPQHSAATSPTNKDCYTDVALPLFENLTIIQQPVDLSSLVEQYMEAAARFIQQARDSSRPFFLYLALAHMHVPLQIAPPPDRGIYGAALREMDALVGHVKHLADSCGKGSTLLWFTGDNGPWMQKCELAGRLGPLLGAWQRAQGGSPAKQTTWEGGHRVPALAYWPGHVPAKRSSHAMLSTLDVFPTLVALAGATLPPNRRFDGMDVSPVLFGLSDVGHKVLLHPNSGAAGKDGAVEALRLAQYKAFYTTGGAKACDGSIGPEEHHRPPLIFNLDRDIQEQEPLDVASREYQAVLPAISRAYAQALEDIATDNTTVADYSKDPAAVPCCSTQHVACRCHAPTSHTASLDQHTDGRATRLCLEGTVMTLKRAAGFNHENCAADNFVMKMKQKQLTT", "length": 567, "header": "tr|A0A8V1AM13-1|A0A8V1AM13_CHICK Computationally mapped isoform of Arylsulfatase G OS=Gallus gallus OX=9031 GN=ARSG PE=3 SV=1 CANONICAL=A0A8V1AI26-1" }, "locus": { "chromosome": "18", "start_pos": 8485640, "end_pos": 8444281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071097.1", "url": "https://www.ensembl.org/id/ENSGALT00010071097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043788.1", "url": "https://www.ensembl.org/id/ENSGALP00010043788.1" } ] } }, { "isoform_ac": "A0A8V1ANK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26/entry#A0A8V1ANK1-1", "sequence": { "sequence": "MGTPAPWSVLLLAVLVGLCTSPVAQGKPNFIVILADDLGWGDLGANWAETKETPHLDELAAEGTRFVDFHSAASTCSPSRASLLTGRLGVRNGVTHNFAISSVGGLPLNETTLAEVLRAAGYSTAAIGKWHLGHHGHHHPIFRGFDYYFGIPYSHDMGCTDTPGYNVPPCPPCPQHSAATSPTNKDCYTDVALPLFENLTIIQQPVDLSSLVEQYMEAAARFIQQARDSSRPFFLYLALAHMHVPLQIAPPPDRGIYGAALREMDALVGHVKHLADSCGKGSTLLWFTGDNGPWMQKCELAGRLGPLLGAWQRAQGGSPAKQTTWEGGHRVPALAYWPGHVPAKRSSHAMLSTLDVFPTLVALAGATLPPNRRFDGMDVSPVLFGLSDVGHKVLLHPNSGAAGKDGAVEALRLAQYKAFYTTGGAKACDGSIGPEEHHRPPLIFNLDRDIQEQEPLDVASREYQAVLPAISRAYAQALEDIATDNTTVADYSKDPAAVPCCSTQHVACRCHAPTSHTASLDQHTDGRATRLCLNVHTVHGHPTQTRIKTRGEQGQLFTYTYSS", "length": 563, "header": "tr|A0A8V1ANK1-1|A0A8V1ANK1_CHICK Computationally mapped isoform of Arylsulfatase G OS=Gallus gallus OX=9031 GN=ARSG PE=3 SV=1 CANONICAL=A0A8V1AI26-1" }, "locus": { "chromosome": "18", "start_pos": 8460538, "end_pos": 8444281, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071095.1", "url": "https://www.ensembl.org/id/ENSGALT00010071095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043786.1", "url": "https://www.ensembl.org/id/ENSGALP00010043786.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:771433", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771433", "resource": "KEGG Pathway" }, { "id": "R-GGA-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-GGA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LGS6-1", "protein_name": "Arylsulfatase G", "gene_name": "Arsg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGWLFLKVLLAGMTFSGLLYPLLDLSISGKTRAPKPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNYPPCPACPQSDGLWRNPERDCYTDVALPLYENLNIVEQPVNLSGLARKYLEKAVAFIEQASTSGRPFLLYMGLAHMHVPLSVTPPLENPGSQRPYRASLQEMDSLVGQIKDKVDHMAKENTLLWITGDNGPWAQKCELAGSVGPFFGLWQTHQGGSSAKQTTWEGGHRVPALAYWPGRVPANATSTALLSMLDIFPTAIALAGASLPPNRNFDGLDVSEVLFGRSQVGHRVLFHPNSGAAGEYGGLQTVRLDHHKAFYITGGAKACDGSTGPEQLHASPLIFNLEDDAAEAAPLQRGSPEYQAVLPKVTRVLADVLQDIADDNSSRADYSQDPSVTPCCSPSQIACRCQTV", "length": 525 }, "evidence": [ { "id": "A0A8V1AI26", "url": "https://omabrowser.org/oma/group/A0A8V1AI26/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1N665-1", "protein_name": "Arylsulfatase G", "gene_name": "ARSG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAWLSLKVWLVGLSFLGCLYPLVDFSFSGETRGQKPNFVIILADDMGWGDLGANWAGTKDTANLDRMAAEGTRFVDFHAAASTCSPSRAALLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLRGAGYVTGMIGKWHLGHHGSHHPNFRGFDYYFGVPYSHDMGCTDTPGYNHPPCPACPRGDRPSRNLERDCYSDVALPLYENLNIVEQPVNLSALAQKYAEKATQFIQQASTSGRPFLLYVGLAHMHVPLAGTPPSAGPRGQRLYSAGLREMDHLVGRIKDTVDLVAKNNTFLWFTGDNGPWAQKCELAGSVGPFTGSWQACRGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSAALLSVLDIFPTVLALAGAPLPQGRRFDGLDVSQVLFGRAQTGHRVLFHPNSGAAGEDGALQTVRLEQYKAFYVTGGARACDGSVGPERHHERPLIFDLEADLAEAAPLDRGGAEYRAVLPRVAAALAGVLADIARDRVSRADYSQDPSVRPCCDPRRPACRCRAA", "length": 525 }, "evidence": [ { "id": "A0A8V1AI26", "url": "https://omabrowser.org/oma/group/A0A8V1AI26/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q32KJ9-1", "protein_name": "Arylsulfatase G", "gene_name": "Arsg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGWLFLKVLLVGMVFSGLLYPFVDFSISGETRAPRPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPSFRGFDYYFGIPYSNDMGCTDNPGYNYPPCPACPQSDGRWRNPDRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLANPQSQRLYRASLQEMDSLVGQIKDKVDHVAKENTLLWFAGDNGPWAQKCELAGSMGPFSGLWQTHQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSLLDIFPTVIALAGASLPPNRKFDGVDVSEVLFGKSQTGHRVLFHPNSGAAGEYGALQTVRLDRYKAFYITGGAKACDGGVGPEQHHVSPLIFNLEDDAAESSPLQKGSPEYQELLPKVTRVLADVLQDIADDNSSQADYTQDPSVTPCCNPYQITCRCQPGE", "length": 526 }, "evidence": [ { "id": "A0A8V1AI26", "url": "https://omabrowser.org/oma/group/A0A8V1AI26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TYD4-1", "protein_name": "Arylsulfatase G", "gene_name": "Arsg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGWLFLKVLLVGMAFSGFFYPLVDFSISGKTRAPQPNIVIILADDMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTHNFAVTSVGGLPVNETTLAEVLRQEGYVTAMIGKWHLGHHGSYHPNFRGFDYYFGIPYSNDMGCTDAPGYNYPPCPACPQRDGLWRNPGRDCYTDVALPLYENLNIVEQPVNLSGLAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLAHPQRQSLYRASLREMDSLVGQIKDKVDHVARENTLLWFTGDNGPWAQKCELAGSVGPFFGLWQTHQGGSPTKQTTWEGGHRVPALAYWPGRVPANVTSTALLSLLDIFPTVIALAGASLPPNRKFDGRDVSEVLFGKSQMGHRVLFHPNSGAAGEYGALQTVRLNHYKAFYITGGAKACDGSVGPEQHHVAPLIFNLEDAADEGMPLQKGSPEYQEVLQQVTRALADVLQDIADDNSSRADYTQDPSVIPCCNPYQTTCRCQPV", "length": 525 }, "evidence": [ { "id": "A0A8V1AI26", "url": "https://omabrowser.org/oma/group/A0A8V1AI26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EG1-1", "protein_name": "Arylsulfatase G", "gene_name": "ARSG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGVTRNFAVTSVGGLPLNETTLAEVLQQAGYVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPSRNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQKYAEKATQFIQRASTSGRPFLLYVALAHMHVPLPVTQLPAAPRGRSLYGAGLWEMDSLVGQIKDKVDHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTTWEGGHRVPALAYWPGRVPVNVTSTALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQPGHRVLFHPNSGAAGEFGALQTVRLERYKAFYITGGARACDGSTGPELQHKFPLIFNLEDDTAEAVPLERGGAEYQAVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQIACRCQAA", "length": 525 }, "evidence": [ { "id": "A0A8V1AI26", "url": "https://omabrowser.org/oma/group/A0A8V1AI26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "pmid": "" }, { "name": "arylsulfatase activity", "id": "GO:0004065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "pmid": "" }, { "name": "N-sulfoglucosamine-3-sulfatase activity", "id": "GO:0033889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033889", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sulfur compound metabolic process", "id": "GO:0006790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17261", "name": "", "equation": "an aryl sulfate + H2O = a phenol + sulfate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5ZK90-1", "A0A8V0YHL1-1", "A0A8V1AI26-1" ], "evidence": [ { "id": "17261", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17261" } ] }, { "id": "R-GGA-1614362", "name": "SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-194653" ], "output_participant_list": [ "R-ALL-1663154" ], "enzyme_list": [ "A0A8V0XXM5-1", "A0A8V1AI26-1", "A0A8V0YHL1-1" ], "evidence": [ { "id": "R-GGA-1614362", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1614362" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1663154", "participant_name": "H2S [endoplasmic reticulum lumen]", "crossref": [ { "id": "29919", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-194653", "participant_name": "NAD+ [endoplasmic reticulum lumen]", "crossref": [ { "id": "57540", "database": "ChEBI", "url": "" }, { "id": "ZINC000008214766", "database": "ZINC", "url": "" }, { "id": "C00003", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XXM5", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] } ] }, { "uniprot_ac": "A0A8V0YHL1", "gene_name": "ARSK", "activity": [ { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ] }, { "ec_number": "3.1.6.18", "activity": "Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ] }, { "ec_number": "3.1.6.1", "activity": "", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ] }, { "ec_number": "3.1.6.18", "activity": "", "evidence": [ { "id": "A0A8V0YHL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL1" } ] } ] }, { "uniprot_ac": "A0A8V1AI26", "gene_name": "ARSG", "activity": [ { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ] }, { "ec_number": "3.1.6.15", "activity": "Hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ] }, { "ec_number": "3.1.6.1", "activity": "", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ] }, { "ec_number": "3.1.6.15", "activity": "", "evidence": [ { "id": "A0A8V1AI26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI26" } ] } ] }, { "uniprot_ac": "Q5ZK90", "gene_name": "ARSK", "activity": [ { "ec_number": "3.1.6.1", "activity": "an aryl sulfate + H2O = a phenol + sulfate + H(+).", "evidence": [ { "id": "Q5ZK90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK90" } ] }, { "ec_number": "3.1.6.18", "activity": "Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.", "evidence": [ { "id": "Q5ZK90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK90" } ] }, { "ec_number": "3.1.6.1", "activity": "", "evidence": [ { "id": "Q5ZK90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZK90" } ] } ] } ], "biomarkers": 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units of heparin.", "evidence": [] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 547, "end_pos": 549 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI46-1", "uniprot_ac": "A0A8V1AI46", "uniprot_id": "A0A8V1AI46_CHICK", "mass": { "chemical_mass": 71631.0, "monoisotopic_mass": 71631.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AI46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46/entry#names_and_taxonomy" } ] } ], "function": 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"MVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSPTVARWVAYLSQRSRLSLSPLKEELQKILGPLTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVLMVIAQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHWKLRHAGQKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLLETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTASGLMQPYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHLTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALKMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPWGRLLEVGGSVNPSVIGVWPTEVIVDTPVFIARGTLIMSMWQIRTPPLVPDIVIQSQISGQRVWYRRPGRAPIQAEVLTQDRNTACILPWRADLPLLVPIKHLFYSP", "length": 636, "header": "tr|A0A8V1AI46-1|A0A8V1AI46_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AI46-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46/entry#A0A8V1AD72-1", "sequence": { "sequence": "MVIAQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHWKLRHAGQKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLLETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTASGLMQPYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHLTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALKMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPWGRLLEVGGSVNPSVIGVWPTEVIVDTPVFIARGTLIMSMWQIRTPPLVPDIVIQSQISGQRVWYRRPGRAPIQAEVLTQDRNTACILPWRADLPLLVPIKHLFYSP", "length": 477, "header": "tr|A0A8V1AD72-1|A0A8V1AD72_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AI46-1" }, "locus": { "chromosome": "28", "start_pos": 408284, "end_pos": 406854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068434.1", "url": "https://www.ensembl.org/id/ENSGALT00010068434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042129.1", "url": "https://www.ensembl.org/id/ENSGALP00010042129.1" } ] } }, { "isoform_ac": "A0A8V1AFU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46/entry#A0A8V1AFU5-1", "sequence": { "sequence": "MVIAQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHWKLRHAGQKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLLETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTASGLMQPYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHLTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALKMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRLAQQNREGDCH", "length": 360, "header": "tr|A0A8V1AFU5-1|A0A8V1AFU5_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AI46-1" }, "locus": { "chromosome": "28", "start_pos": 408284, "end_pos": 406648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068429.1", "url": "https://www.ensembl.org/id/ENSGALT00010068429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042126.1", "url": "https://www.ensembl.org/id/ENSGALP00010042126.1" } ] } }, { "isoform_ac": "A0A8V1AI46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46/entry#A0A8V1AI46-1", "sequence": { "sequence": "MVEKQLLATYSALQAVEPITQTAEVIVKTTLPIQGWVKDLTHIPKTGVAQSPTVARWVAYLSQRSRLSLSPLKEELQKILGPLTYHSETPEEIVVTCPEKSPVQEGKYPIPEDAWYTDGSSRGNPSRWRAVAYHPSTETIWFEEGDGQSSQWAELRAVLMVIAQEPGNSALNICTDSWAVYRGLTLWIAQWATQDWTIHARPIWGKDMWVDIWNVVRHRTVRAYHVSGHQPLQSPGNDEADTLARVRWLGSTPSEDIAHWLHWKLRHAGQKTMWAAAKAWGLPIQLPDIVQACQDCDACSRMRPRPLLETTAHLARGHNPLQRWQIDYIGPLPRSEGARYALTCVDTASGLMQPYPVAKANQAYTIKALTRLMASYGTPEVIESDQGTHLTGATVQKWAEDNNIEWRFHLPYNPTGAGLIERYNGILKAALKADSQSLQGWTKRLYETLRDLNERPRDGRPSALKMLQTTWASPLRIQITSKDTSLKPQVGTMNNLLLPAPDDLEPGRHKVKWPWKVQAGPKWCGLLAPWGRLLEVGGSVNPSVIGVWPTEVIVDTPVFIARGTLIMSMWQIRTPPLVPDIVIQSQISGQRVWYRRPGRAPIQAEVLTQDRNTACILPWRADLPLLVPIKHLFYSP", "length": 636, "header": "tr|A0A8V1AI46-1|A0A8V1AI46_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AI46-1" }, "locus": { "chromosome": "28", "start_pos": 408761, "end_pos": 406854, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068432.1", "url": "https://www.ensembl.org/id/ENSGALT00010068432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042128.1", "url": "https://www.ensembl.org/id/ENSGALP00010042128.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI46", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI46", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI46", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI46", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI46", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AI46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 482, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AI46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI46" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 249, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12947", "database": "Pfam", "categories": [ "Protein Classification", 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"MNHQRVPTMKSEEEDTFVWAVTAPCASYVDECGTISGVCDGGECTNTAGSYVCTCPRGFMTSHDGSRCIDQRVGTCFSALIGGRCAGDLPGQYTKMQCCCDSGRCWAIGQTPEMCPVRGSDEYRRLCIEGLPVVPGFPGSFPGIPGFGPNGVGPGLNGPGGIGPNGANGQGGIPGLPGMGPGSSSIGTATLNQTIDICKHFTNLCLNGRCIPTPSSYRCECNMGYKQDVRGECIDVDECSSSPCVHGDCVNTPGSYHCKCHEGFQSTPTKQACIDIDECIMNGVMCRNGRCVNTDGSFQCICNAGFEITPDGKNCVDHDECATTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCVDIDECETPGICMNGWCINTEGSFRCECLGGLAIGVDGRVCVDTHMRSTCYGGIKKGTCARPFPGAVTKSECCCANPDHGFGEPCQPCPAKNSAEFQALCSSGIGITADGRDINECALNPDICPNGMCENLRGSYRCICNLGYESDPTGKNCVDVDECTVNRLLCDNGLCRNTPGSYTCTCPKGFVFRTETDTCEDINECTSNPCVNGVCRNNAGSFACECSPGSKLDPSGTICVDSMKGTCWLNIQDGRCEVNINGATLKSECCATLGAAWGSPCERCEIDTACPRGYARMKGVTCEDVNECDVFPGVCPNGRCVNTAGSFRCECPEGLTLDGTARTCVDVRVEQCYMKWDEDECTEPLPGKYRIDMCCCSVGSAWGIDCEECPKVGSNEYKAICPRGPGFANRGDVLSGRPFYKDVNECKVFSGLCTHGTCRNTIGSFRCICGNGFALDAEERNCTDIDECRISPDLCGHGTCVNTPGSFECECFEGYESGFMMMKNCMDINECERDPLLCRGGICMNTDGSFECICPPGHELTSEGNTCIDINECSLSDNLCRNGRCVNVIGTYQCACDPGFQATPDRQGCVDIDECTITNGGCDTHCSNSEGSYECSCSEGYALMPDKRSCADIDECEDNPDICDGGQCTNIPGEYRCLCFDGFMASLDMKTCIDVNECDLNPNICLHGECENTKGSFICHCQLGYFVKKGTTGCTDIDECEIGAHNCDMHASCINVPGSFKCKCRTGWLGDGLKCNDLDECATEEHKCNLNANCINTPGSYRCACREGFNGDGFSCSDVDECADNVNLCENGQCLNAPGGYRCECEMGFNPTEDSKACQDIDECTFQNICVFGTCQNLPGMFRCACDDGYELDRSGGNCTDINECADPVNCINGLCVNTPGSYLCNCPQDFELNPTGVGCVDTRVGNCFLDTQDRGDGGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPPANTTEYKTLCPGGEGFRPNPITVILEDIDECQELPGLCQGGNCVNTFGSFQCECPLGYYLNEDTRICEDIDECSAHIGICGPGTCYNTLGNYTCVCPPEYMQVNGGNNCMDMRKSVCYRNYNDTCENELSFNMTKKMCCCSYNIGKAWNKPCEPCPTPASPEYQILCGNQAPGFIIDIHTGKPIDIDECSEIPAICTNGVCINQIGSFRCECPIGFSYNNILLICEDIDECSSGENLCQRNADCINIPGSYRCECSTGYKLSPSGACVGRNECQEIPNVCSHGDCVDTEGSYICICHNGFKATGEQTMCMDIDECDRQPCGNGTCKNTVGSYNCLCFPGFELTHNNDCMDIDECSSMLGQVCRNGQCINSIGSFQCLCQEGYDRTPDGKNCVDINECVSLPGTCSPGTCQNLEGSFRCICPPGYEVQNDNCIDINECEEEPNICLFGTCTNTPGSFQCVCPPGFVLSDNGRRCFDTRQSFCFTRFDNGKCSVPKAFNTTKARCCCSKMPGEGWGDPCELCPQEGNVAFQELCPYGHGAIPGPGDTREDVNECSENLGVCINGACINTDGSFRCECPFGYNLDYTGVNCVDTDECSIGNPCGNGTCTNVVGGFECACDEGFEPGPMMTCEDINECASNPLLCAFRCINTFGSYECTCPSGYALRDDRRMCRDLDECAEGLHDCESRGMLCKNLIGTFMCICPPGMQRRPDGEGCTDENECRTKPGICPNGRCINTVGSYRCDCNEGFEVSPSGTECIDTRQGFCFTEVLQTMCQMSSTNRNLVTKSECCCNSGRSWGPQCELCPLLGTAQYKKMCPHGPGYSTDGRDIDECKVLPNLCKNGQCINSIGSFRCHCRLGYTADITGTACVDLDECNQSPKPCNFICKNTEGSYQCSCPRGYVLQEDGKICKDLDECSTKQHNCQFLCVNVIGGFNCKCPPGFTQHHSSCIDNNECTAQPSLCGAKGQCLNTPGSYNCECQKGFSLDSSGVNCEDVDECDGNHRCQHGCQNVLGGYRCGCPQGYVQHYQWNQCVDENECSSPTACGSASCYNTLGSFKCVCPSGFDFDQAFGGCQDVDECSAGGSPCSYGCSNTDGGYLCGCPGGYFRAGQGHCISGLGFGKGSYLPAPQEEDEDNLLSPETCYECKINGYPKRGRQRRSVNGTERHKDHTVNLASMDVEAPLSMMLNLSDLAHNEHILELLPAVEPLENRVRYLISHGNEDGFFRIHQKEGLSFLHLGRKKIVPGTYLLEIMSVPLYRKRELQKLEAKNDLNYLAGELGQALRMKLQLQLY", "length": 2611, "header": "tr|A0A8V1AI65-1|A0A8V1AI65_CHICK Isoform 1 of Fibrillin 3 OS=Gallus gallus OX=9031 GN=FBN3 PE=1 SV=1 CANONICAL=A0A8V1AI65-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AI65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI65/entry#A0A8V1AI65-1", "sequence": { "sequence": "MNHQRVPTMKSEEEDTFVWAVTAPCASYVDECGTISGVCDGGECTNTAGSYVCTCPRGFMTSHDGSRCIDQRVGTCFSALIGGRCAGDLPGQYTKMQCCCDSGRCWAIGQTPEMCPVRGSDEYRRLCIEGLPVVPGFPGSFPGIPGFGPNGVGPGLNGPGGIGPNGANGQGGIPGLPGMGPGSSSIGTATLNQTIDICKHFTNLCLNGRCIPTPSSYRCECNMGYKQDVRGECIDVDECSSSPCVHGDCVNTPGSYHCKCHEGFQSTPTKQACIDIDECIMNGVMCRNGRCVNTDGSFQCICNAGFEITPDGKNCVDHDECATTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCVDIDECETPGICMNGWCINTEGSFRCECLGGLAIGVDGRVCVDTHMRSTCYGGIKKGTCARPFPGAVTKSECCCANPDHGFGEPCQPCPAKNSAEFQALCSSGIGITADGRDINECALNPDICPNGMCENLRGSYRCICNLGYESDPTGKNCVDVDECTVNRLLCDNGLCRNTPGSYTCTCPKGFVFRTETDTCEDINECTSNPCVNGVCRNNAGSFACECSPGSKLDPSGTICVDSMKGTCWLNIQDGRCEVNINGATLKSECCATLGAAWGSPCERCEIDTACPRGYARMKGVTCEDVNECDVFPGVCPNGRCVNTAGSFRCECPEGLTLDGTARTCVDVRVEQCYMKWDEDECTEPLPGKYRIDMCCCSVGSAWGIDCEECPKVGSNEYKAICPRGPGFANRGDVLSGRPFYKDVNECKVFSGLCTHGTCRNTIGSFRCICGNGFALDAEERNCTDIDECRISPDLCGHGTCVNTPGSFECECFEGYESGFMMMKNCMDINECERDPLLCRGGICMNTDGSFECICPPGHELTSEGNTCIDINECSLSDNLCRNGRCVNVIGTYQCACDPGFQATPDRQGCVDIDECTITNGGCDTHCSNSEGSYECSCSEGYALMPDKRSCADIDECEDNPDICDGGQCTNIPGEYRCLCFDGFMASLDMKTCIDVNECDLNPNICLHGECENTKGSFICHCQLGYFVKKGTTGCTDIDECEIGAHNCDMHASCINVPGSFKCKCRTGWLGDGLKCNDLDECATEEHKCNLNANCINTPGSYRCACREGFNGDGFSCSDVDECADNVNLCENGQCLNAPGGYRCECEMGFNPTEDSKACQDIDECTFQNICVFGTCQNLPGMFRCACDDGYELDRSGGNCTDINECADPVNCINGLCVNTPGSYLCNCPQDFELNPTGVGCVDTRVGNCFLDTQDRGDGGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPPANTTEYKTLCPGGEGFRPNPITVILEDIDECQELPGLCQGGNCVNTFGSFQCECPLGYYLNEDTRICEDIDECSAHIGICGPGTCYNTLGNYTCVCPPEYMQVNGGNNCMDMRKSVCYRNYNDTCENELSFNMTKKMCCCSYNIGKAWNKPCEPCPTPASPEYQILCGNQAPGFIIDIHTGKPIDIDECSEIPAICTNGVCINQIGSFRCECPIGFSYNNILLICEDIDECSSGENLCQRNADCINIPGSYRCECSTGYKLSPSGACVGRNECQEIPNVCSHGDCVDTEGSYICICHNGFKATGEQTMCMDIDECDRQPCGNGTCKNTVGSYNCLCFPGFELTHNNDCMDIDECSSMLGQVCRNGQCINSIGSFQCLCQEGYDRTPDGKNCVDINECVSLPGTCSPGTCQNLEGSFRCICPPGYEVQNDNCIDINECEEEPNICLFGTCTNTPGSFQCVCPPGFVLSDNGRRCFDTRQSFCFTRFDNGKCSVPKAFNTTKARCCCSKMPGEGWGDPCELCPQEGNVAFQELCPYGHGAIPGPGDTREDVNECSENLGVCINGACINTDGSFRCECPFGYNLDYTGVNCVDTDECSIGNPCGNGTCTNVVGGFECACDEGFEPGPMMTCEDINECASNPLLCAFRCINTFGSYECTCPSGYALRDDRRMCRDLDECAEGLHDCESRGMLCKNLIGTFMCICPPGMQRRPDGEGCTDENECRTKPGICPNGRCINTVGSYRCDCNEGFEVSPSGTECIDTRQGFCFTEVLQTMCQMSSTNRNLVTKSECCCNSGRSWGPQCELCPLLGTAQYKKMCPHGPGYSTDGRDIDECKVLPNLCKNGQCINSIGSFRCHCRLGYTADITGTACVDLDECNQSPKPCNFICKNTEGSYQCSCPRGYVLQEDGKICKDLDECSTKQHNCQFLCVNVIGGFNCKCPPGFTQHHSSCIDNNECTAQPSLCGAKGQCLNTPGSYNCECQKGFSLDSSGVNCEDVDECDGNHRCQHGCQNVLGGYRCGCPQGYVQHYQWNQCVDENECSSPTACGSASCYNTLGSFKCVCPSGFDFDQAFGGCQDVDECSAGGSPCSYGCSNTDGGYLCGCPGGYFRAGQGHCISGLGFGKGSYLPAPQEEDEDNLLSPETCYECKINGYPKRGRQRRSVNGTERHKDHTVNLASMDVEAPLSMMLNLSDLAHNEHILELLPAVEPLENRVRYLISHGNEDGFFRIHQKEGLSFLHLGRKKIVPGTYLLEIMSVPLYRKRELQKLEAKNDLNYLAGELGQALRMKLQLQLY", "length": 2611, "header": "tr|A0A8V1AI65-1|A0A8V1AI65_CHICK Isoform 1 of Fibrillin 3 OS=Gallus gallus OX=9031 GN=FBN3 PE=1 SV=1 CANONICAL=A0A8V1AI65-1" }, "locus": { "chromosome": "28", "start_pos": 807043, "end_pos": 748129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068518.1", "url": "https://www.ensembl.org/id/ENSGALT00010068518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042150.1", "url": "https://www.ensembl.org/id/ENSGALP00010042150.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1480, "start_aa": "Thr", "end_pos": 1480, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1480", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI65" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI65" } ], "pmid": "" }, { "name": "embryonic morphogenesis", "id": "GO:0048598", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048598", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI65" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI65" } ], "pmid": "" }, { "name": "microfibril", "id": "GO:0001527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI65" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1229, "end_pos": 1231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1325, "end_pos": 1327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1414, "end_pos": 1416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1445, "end_pos": 1447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1455, "end_pos": 1457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1645, "end_pos": 1647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1820, "end_pos": 1822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1925, "end_pos": 1927, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2196, "end_pos": 2198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2481, "end_pos": 2483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2507, "end_pos": 2509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" } ], 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"o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI71-1", "uniprot_ac": "A0A8V1AI71", "uniprot_id": "A0A8V1AI71_CHICK", "mass": { "chemical_mass": 65857.0, "monoisotopic_mass": 65857.0 }, "refseq": { "ac": "XP_003642037", "name": "synapsin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642037" }, "gene_names": [ { "name": "SYN2", "type": "recommended", "evidence": [ { "id": "A0A8V1AI71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71" } ] }, { "name": "SYN2", "type": "synonym", "evidence": [ { "id": "XP_003642037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642037" } ] } ], "protein_names": [ { "name": "Synapsin-2", "type": "recommended", "evidence": [ { "id": "A0A8V1AI71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71/entry#names_and_taxonomy" } ] }, { "name": "Synapsin II", "type": "synonym", "evidence": [ { "id": "A0A8V1AI71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71/entry#names_and_taxonomy" } ] }, { "name": "synapsin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003642037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642037" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642037.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642037" } ] }, { "annotation": "Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71#function" }, { "database": "UniProtKB", "id": "ARBA00056023", "url": "https://www.uniprot.org/uniprotkb/ARBA00056023#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71", "locus": { "chromosome": "12", "start_pos": 4990745, "end_pos": 4845702, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027905", "url": "https://www.ensembl.org/id/ENSGALG00010027905" } ] } } ], "crossref": [ { "id": "A0A8V1AI71", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AI71", "database": "AlphaFoldDB", "categories": [] }, { "id": "415963", "url": "https://www.ncbi.nlm.nih.gov/gene/415963", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415963", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415963", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCEIFGG", "url": "https://omabrowser.org/oma/group/CCEIFGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB08", "url": "https://www.orthodb.org/?gene=A0A8V1AB08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADT0", "url": "https://www.orthodb.org/?gene=A0A8V1ADT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI67", "url": "https://www.orthodb.org/?gene=A0A8V1AI67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI71", "url": "https://www.orthodb.org/?gene=A0A8V1AI71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10841", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10841", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10841:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10841:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02750", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02750", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642037", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB08", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNFLRRRLSDSSFIANLPNGYMTDLQRPDPQQPPPPPPSASSAPASGSPAAERRQPPQSAPPQQQPPPPQQSAGSSFFSSLSNAVKQTAASAGLVDPTSASSSAAGRKFKLLLVIDEPHTDWAKAFRGKKVHGEYDIKVEQAEFSEINLIAHADGNYAVDIQVFRNGTKVVRSFRPDFVLVRQHSFSMAENEDFRNLIIGLQYAGIPSVNSLESIYNFCDKPWVFAQLVSVYKTLGPEKFPLIEQTFYPNHKEMLTMLTFPVVVKIGHAHSGMGKIKVDNHYDFQDIASVVALTQTYATTEPFIDSKYDIRIQKIGSNYKAYMRTSISGNWKTNTGSAMLEQIAMSDKYKLWVDTCSEIFGGLDICAVKAVHGKDGKDYIFEVMDCAMPLIGEHQIEDRQHITELVVSKMNQMLSKTPIPSPQRPTATQQPQSGSLKEPEPNKIPPQRPPPQGGPVQPQGMQSQSQEPLQPQRMYPPGQSAKPSTSQPQRPPGPTTQQPRAQAQGPSSTRIQKEAEAQPAPQPQPAPQPQPAPQPAPQPASQQKPQSHPQLNKSQSLTNAFSFTESSFFRSSVNEDEAKAETIRNLRKSFASLFSD", "length": 597, "header": "tr|A0A8V1AI71-1|A0A8V1AI71_CHICK Isoform 1 of Synapsin-2 OS=Gallus gallus OX=9031 GN=SYN2 PE=1 SV=1 CANONICAL=A0A8V1AI71-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71/entry#A0A8V1AB08-1", "sequence": { "sequence": "MLIQAWERRTSISGNWKTNTGSAMLEQIAMSDKYKLWVDTCSEIFGGLDICAVKAVHGKDGKDYIFEVMDCAMPLIGEHQIEDRQHITELVVSKMNQMLSKTPIPSPQRPTATQQPQSGSLKEPEPNKIPPQRPPPQGGPVQPQGMQSQSQEPLQPQRMYPPGQSAKPSTSQPQRPPGPTTQQPRAQAQGPSSTRIQKEAEAQPAPQPQPAPQPQPAPQPAPQPASQQKPQSHPQLNKSQSLTNAFSFTESSFFRSSVNEDEAKAETIRNLRKSFASLFSD", "length": 281, "header": "tr|A0A8V1AB08-1|A0A8V1AB08_CHICK Computationally mapped isoform of Synapsin II OS=Gallus gallus OX=9031 GN=SYN2 PE=1 SV=1 CANONICAL=A0A8V1AI71-1" }, "locus": { "chromosome": "12", "start_pos": 4989787, "end_pos": 4947259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067642.1", "url": "https://www.ensembl.org/id/ENSGALT00010067642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041385.1", "url": "https://www.ensembl.org/id/ENSGALP00010041385.1" } ] } }, { "isoform_ac": "A0A8V1ADT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71/entry#A0A8V1ADT0-1", "sequence": { "sequence": "MMNFLRRRLSDSSFIANLPNGYMTDLQRPDPQQPPPPPPSASSAPASGSPAAERRQPPQSAPPQQQPPPPQQSAGSSFFSSLSNAVKQTAASAGLVDPTSASSSAAGRKFKLLLVIDEPHTDWAKAFRGKKVHGEYDIKVEQAEFSEINLIAHADGNYAVDIQVFRNGTKVVRSFRPDFVLVRQHSFSMAENEDFRNLIIGLQYAGIPSVNSLESIYNFCDKPWVFAQLVSVYKTLGPEKFPLIEQTFYPNHKEMIKVDNHYDFQDIASVVALTQTYATTEPFIDSKYDIRIQKIGSNYKAYMRTSISGNWKTNTGSAMLEQIAMSDKYKLWVDTCSEIFGGLDICAVKAVHGKDGKDYIFEVMDCAMPLIGEHQIEDRQHITELVVSKMNQMLSKTPIPSPQRPTATQQPQSGSLKEPEPNKIPPQRPPPQGGPVQPQGMQSQSQEPLQPQRMYPPGQSAKPSTSQPQRPPGPTTQQPRAQAQGPSSTRIQKEAEAQPAPQPQPAPQPQPAPQPAPQPASQQKPQSHPQLNKSQSLTNAFSFTESSFFRSSVNEDEAKAETIRNLRKSFASLFSD", "length": 576, "header": "tr|A0A8V1ADT0-1|A0A8V1ADT0_CHICK Computationally mapped isoform of Synapsin II OS=Gallus gallus OX=9031 GN=SYN2 PE=1 SV=1 CANONICAL=A0A8V1AI71-1" }, "locus": { "chromosome": "12", "start_pos": 4989787, "end_pos": 4845848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067644.1", "url": "https://www.ensembl.org/id/ENSGALT00010067644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041387.1", "url": "https://www.ensembl.org/id/ENSGALP00010041387.1" } ] } }, { "isoform_ac": "A0A8V1AI67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71/entry#A0A8V1AI67-1", "sequence": { "sequence": "MEPKLTMLTFPVVVKIGHAHSGMGKIKVDNHYDFQDIASVVALTQTYATTEPFIDSKYDIRIQKIGSNYKAYMRTSISGNWKTNTGSAMLEQIAMSDKYKLWVDTCSEIFGGLDICAVKAVHGKDGKDYIFEVMDCAMPLIGEHQIEDRQHITELVVSKMNQMLSKTPIPSPQRPTATQQPQSGSLKEPEPNKIPPQRPPPQGCLQYILDCNGVAVGPKQVQAT", "length": 224, "header": "tr|A0A8V1AI67-1|A0A8V1AI71_CHICK Computationally mapped isoform of Synapsin-2 OS=Gallus gallus OX=9031 GN=SYN2 PE=1 SV=1 CANONICAL=A0A8V1AI71-1" }, "locus": { "chromosome": "12", "start_pos": 4983376, "end_pos": 4946950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067641.1", "url": "https://www.ensembl.org/id/ENSGALT00010067641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041384.1", "url": "https://www.ensembl.org/id/ENSGALP00010041384.1" } ] } }, { "isoform_ac": "A0A8V1AI71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI71/entry#A0A8V1AI71-1", "sequence": { "sequence": "MMNFLRRRLSDSSFIANLPNGYMTDLQRPDPQQPPPPPPSASSAPASGSPAAERRQPPQSAPPQQQPPPPQQSAGSSFFSSLSNAVKQTAASAGLVDPTSASSSAAGRKFKLLLVIDEPHTDWAKAFRGKKVHGEYDIKVEQAEFSEINLIAHADGNYAVDIQVFRNGTKVVRSFRPDFVLVRQHSFSMAENEDFRNLIIGLQYAGIPSVNSLESIYNFCDKPWVFAQLVSVYKTLGPEKFPLIEQTFYPNHKEMLTMLTFPVVVKIGHAHSGMGKIKVDNHYDFQDIASVVALTQTYATTEPFIDSKYDIRIQKIGSNYKAYMRTSISGNWKTNTGSAMLEQIAMSDKYKLWVDTCSEIFGGLDICAVKAVHGKDGKDYIFEVMDCAMPLIGEHQIEDRQHITELVVSKMNQMLSKTPIPSPQRPTATQQPQSGSLKEPEPNKIPPQRPPPQGGPVQPQGMQSQSQEPLQPQRMYPPGQSAKPSTSQPQRPPGPTTQQPRAQAQGPSSTRIQKEAEAQPAPQPQPAPQPQPAPQPAPQPASQQKPQSHPQLNKSQSLTNAFSFTESSFFRSSVNEDEAKAETIRNLRKSFASLFSD", "length": 597, "header": "tr|A0A8V1AI71-1|A0A8V1AI71_CHICK Isoform 1 of Synapsin-2 OS=Gallus gallus OX=9031 GN=SYN2 PE=1 SV=1 CANONICAL=A0A8V1AI71-1" }, "locus": { "chromosome": "12", "start_pos": 4989787, "end_pos": 4845848, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067646.1", "url": "https://www.ensembl.org/id/ENSGALT00010067646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041389.1", "url": "https://www.ensembl.org/id/ENSGALP00010041389.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 496, "start_aa": "Thr", "end_pos": 496, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr496", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415963", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415963", "resource": "KEGG Pathway" }, { "id": "R-GGA-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-GGA-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R0A8-1", "protein_name": "Synapsin-2a", "gene_name": "syn2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNYLRRRLSDSTFISNLPNGYMSDLQKPDPPQPPPPGPAPVPAPASGPAPVSPRQERKPIQPQPGLGTGFFSSITNVVKQTAASAGLVEQTSVPASSKRIKILLVIDEPQHDWAKLFRGKKLNGDYDIKVEQAEFGDISIVAHANGSCNVAVQVLQNENKVLRSFKPDFVLIRQHAFSMTENEDFRNLIIGLQYAGIPSINSLESVYNLCDKPWAFACLINTYKKLGQEKFPLIEQTFYPNYKEMVTMPAFPVVVKIGHAHSGVGKVKVENHTKFQDIASVVAITQTYSTCEPFIDPKYDIRIQKIGNDYKAYMRTSVSGNWKSNTGTAMVEQVAMTDRYKLWVDTCCEIFGGLEICAVKAINGKDGKDYITEVMGSSMPLMGEHQAQDQQLIADMVIAKMNHVMAQNPKRPTAIQPKQITVENNTLVEVKNAPPQKAPPQGCLQYILDCNGVAVGPKLVQAN", "length": 463 }, "evidence": [ { "id": "A0A8V1AI71", "url": "https://omabrowser.org/oma/group/A0A8V1AI71/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q63537-1", "protein_name": "Synapsin-2", "gene_name": "Syn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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] }, { "id": "R-GGA-186763", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-186763", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8875555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8875555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-912631", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-912631", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A883", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A883", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A883-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A883-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI70", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCFCVFLDSERSHLSSFTMKLKGKFHSPKIKRTPSKKGKQADLTVKTPEKSANKVSKWRASSPRLTGFLLSVTQVLRSTALLSNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQSDPRIQQSSAISSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKDVIKAVLDGVKELVKLTIEKQEHPSPTSPVKPSLPACKSDSPSELPLTDREMEILNKTTNMTQSNELLTDSMDEEVAPPKPPLPCIRVAENSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQVPTTLSPLPESLGESGSPFHGHAFQLPQGSSSPLEFCSLSGAVQPTETPPALPEKKRRSAASQTSDSSCRVSYERHPSQYDNISEDDMQNAGSLSSVPCTPFAPILPFQQGNSSAQVEFIADFAAPDSNSDPEKPPPLPEKKNKHMMAYMQFVEDYSEPQPSMFYQTPQNEHIYQQKNKHLMEVYGFNDSFISLDPSQDLAPPPALPPKQRQLASYAASSFPSVSYCVQQTKVPFTPEDTGAAQGLTMSVSNSFLNRHSSFPVHSYKSVFRSYSQDFVPHNQVSVPPFLSSTSSSCSTAPFPPVHPSPSSDLAVPATASPSPSTGDVPNSSSQESSFNGSAPVCLPSETSLTDSLENASEEAGEGEYVNLYSSGQSNGELPHSGGESPSVKDGHSKDSTSNSSAMGKEGKDGAERQQQSPDALESSQLEEEVDELSLIDHSEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFITPEELIKKLHKNTFFVLVRVVDELCLVELTEEILKLLMDLVFRLVCNGELSLARVLRKNILDKVDQKKMLRYANSIKPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQDLTFVHLGNPDYIDSKVNFSKRWQQFNILDSMRCFQQVHYDIKRNDDIVSFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT", "length": 1227, "header": "tr|A0A8V1AK14-1|A0A8V1AK14_CHICK Isoform 1 of CRK SH3-binding GNRP OS=Gallus gallus OX=9031 GN=RAPGEF1 PE=4 SV=1 CANONICAL=A0A8V1AK14-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A883-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14/entry#A0A8V1A883-1", "sequence": { "sequence": "CFPGLGTCLPIHPNLVMCFCVFLDSERSHLSSFTMKLKGKFHSPKIKRTPSKKGKQADLTVKTPEKSANKVSKWRASSPRLTGFLLSVTQVLRSTALLSVCDFNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQSDPRIQQSSAISSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKDVIKAVLDGVKELVKLTIEKQEHPSPTSPVKPSLPACKSDSPSELPLTDREMEILNKTTNMTQSNELLTDSMDEEVAPPKPPLPCIRVAENSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQVPTTLSPLPESLGESGSPFHGHAFQLPQGSSSPLEFCSLSGAVQPTETPPALPEKKRRSAASQTSDSSCRVSYERHPSQYDNISEDDMQNAGSLSSVPCTPFAPILPFQQGNSSAQVEFIADFAAPDSNSDPEKPPPLPEKKNKHMMAYMQFVEDYSEPQPSMFYQTPQNEHIYQQKNKHLMEVYGFNDSFISLDPSQDLAPPPALPPKQRQLESPSVKDGHSKDSTSNSSAMGKEGKDGAERQQQSPDALESSQLEEEVDELSLIDHSEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFITPEELIKKLHKNTFFVLVRVVDELCLVELTEEILKLLMDLVFRLVCNGELSLARVLRKNILDKVDQKKMLRYANSIKPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQDLTFVHLGNPDYIDSKVNFSKRWQQFNILDSMRCFQQVHYDIKRNDDIVSFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT", "length": 1075, "header": "tr|A0A8V1A883-1|A0A8V1A883_CHICK Computationally mapped isoform of CRK SH3-binding GNRP OS=Gallus gallus OX=9031 GN=RAPGEF1 PE=4 SV=1 CANONICAL=A0A8V1AK14-1" }, "locus": { "chromosome": "17", "start_pos": 6896526, "end_pos": 6848514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068554.1", "url": "https://www.ensembl.org/id/ENSGALT00010068554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042162.1", "url": "https://www.ensembl.org/id/ENSGALP00010042162.1" } ] } }, { "isoform_ac": "A0A8V1ADA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14/entry#A0A8V1ADA1-1", "sequence": { "sequence": "MCFCVFLDSERSHLSSFTMKLKGKFHSPKIKRTPSKKGKQADLTVKTPEKSANKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQSDPRIQQSSAISSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKDVIKAVLDGVKELVKLTIEKQEHPSPTSPVKPSLPACKSDSPSELPLTDREMEILNKTTNMTQSNELLTDSMDEEVAPPKPPLPCIRVAENSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQVPTTLSPLPESLGESGSPFHGHAFQLPQGSSSPLEFCSLSGAVQPTETPPALPEKKRRSAASQTSDSSCRVSYERHPSQYDNISEDDMQNAGSLSSVPCTPFAPILPFQQGNSSAQVEFIADFAAPDSNSDPEKPPPLPEKKNKHMMAYMQFVEDYSEPQPSMFYQTPQNEHIYQQKNKHLMEVYGFNDSFISLDPSQDLAPPPALPPKQRQLSENASEEAGEGEYVNLYSSGQSNGELPHSGGESPSVKDGHSKDSTSNSSAMGKEGKDGAERQQQSPDALESSQLEEEVDELSLIDHSEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFITPEELIKKLHKNTFFVLVRVVDELCLVELTEEILKLLMDLVFRLVCNGELSLARVLRKNILDKVDQKKMLRYANSIKPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQDLTFVHLGNPDYIDSKVNFSKRWQQFNILDSMRCFQQVHYDIKRNDDIVSFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT", "length": 1057, "header": "tr|A0A8V1ADA1-1|A0A8V1ADA1_CHICK Computationally mapped isoform of CRK SH3-binding GNRP OS=Gallus gallus OX=9031 GN=RAPGEF1 PE=4 SV=1 CANONICAL=A0A8V1AK14-1" }, "locus": { "chromosome": "17", "start_pos": 6896057, "end_pos": 6848514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068534.1", "url": "https://www.ensembl.org/id/ENSGALT00010068534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042154.1", "url": "https://www.ensembl.org/id/ENSGALP00010042154.1" } ] } }, { "isoform_ac": "A0A8V1ADA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14/entry#A0A8V1ADA7-1", "sequence": { "sequence": "CFPGLGTCLPIHPNLVMCFCVFLDSERSHLSSFTMKLKGKFHSPKIKRTPSKKGKQADLTVKTPEKSANKNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQSDPRIQQSSAISSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKDVIKAVLDGVKELVKLTIEKQEHPSPTSPVKPSLPACKSDSPSELPLTDREMEILNKTTNMTQSNELLTDSMDEEVAPPKPPLPCIRVAENSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQVPTTLSPLPESLGESGSPFHGHAFQLPQGSSSPLEFCSLSGAVQPTETPPALPEKKRRSAASQTSDSSCRVSYERHPSQYDNISEDDMQNAGSLSSVPCTPFAPILPFQQGNSSAQVEFIADFAAPDSNSDPEKPPPLPEKKNKHMMAYMQFVEDYSEPQPSMFYQTPQNEHIYQQKNKHLMEVYGFNDSFISLDPSQDLAPPPALPPKQRQLQASYAASSFPSVSYCVQQTKVPFTPEDTGAAQGLTMSVSNSFLNRHSSFPVHSYKSVFRSYSQDFVPHNQVSVPPFLSSTSSSCSTAPFPPVHPSPSSDLAVPATASPSPSTGDVPNSSSQESSFNGSAPVCLPSETSLTDSLENASEEAGEGEYVNLYSSGQSNGELPHSGGVSNRERPRTGKGLPGSPDALESSQLEEEVDELSLIDHSEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFITPEELIKKLHKNTFFVLVRVVDELCLVELTEEILKLLMDLVFRLVCNGELSLARVLRKNILDKVDQKKMLRYANSIKPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQDLTFVHLGNPDYIDSKVNFSKRWQQFNILDSMRCFQQVHYDIKRNDDIVSFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT", "length": 1197, "header": "tr|A0A8V1ADA7-1|A0A8V1ADA7_CHICK Computationally mapped isoform of CRK SH3-binding GNRP OS=Gallus gallus OX=9031 GN=RAPGEF1 PE=4 SV=1 CANONICAL=A0A8V1AK14-1" }, "locus": { "chromosome": "17", "start_pos": 6896526, "end_pos": 6848514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068551.1", "url": "https://www.ensembl.org/id/ENSGALT00010068551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042159.1", "url": "https://www.ensembl.org/id/ENSGALP00010042159.1" } ] } }, { "isoform_ac": "A0A8V1ADB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14/entry#A0A8V1ADB4-1", "sequence": { "sequence": "MRLLLDHQKTLKRHFSKGPSDSERSHLSSFTMKLKGKFHSPKIKRTPSKKGKQADLTVKTPEKSANKVSKWRASSPRLTGFLLSVTQVLRSTALLSVCDFNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQSDPRIQQSSAISSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKDVIKAVLDGVKELVKLTIEKQEHPSPTSPVKPSLPACKSDSPSELPLTDREMEILNKTTNMTQSNELLTDSMDEEVAPPKPPLPCIRVAENSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQVPTTLSPLPESLGESGSPFHGHAFQLPQGSSSPLEFCSLSGAVQPTETPPALPEKKRRSAASQTSDSSCRVSYERHPSQYDNISEDDMQNAGSLSSVPCTPFAPILPFQQGNSSAQVEFIADFAAPDSNSDPEKPPPLPEKKNKHMMAYMQFVEDYSEPQPSMFYQTPQNEHIYQQKNKHLMEVYGFNDSFISLDPSQDLAPPPALPPKQRQLESPSVKDGHSKDSTSNSSAMGKEGKDGAERQQQSPDALESSQLEEEVDELSLIDHSEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFITPEELIKKLHKNTFFVLVRVVDELCLVELTEEILKLLMDLVFRLVCNGELSLARVLRKNILDKVDQKKMLRYANSIKPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQDLTFVHLGNPDYIDSKVNFSKRWQQFNILDSMRCFQQVHYDIKRNDDIVSFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT", "length": 1072, "header": "tr|A0A8V1ADB4-1|A0A8V1ADB4_CHICK Computationally mapped isoform of CRK SH3-binding GNRP OS=Gallus gallus OX=9031 GN=RAPGEF1 PE=4 SV=2 CANONICAL=A0A8V1AK14-1" }, "locus": { "chromosome": "17", "start_pos": 6896796, "end_pos": 6848514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068556.1", "url": "https://www.ensembl.org/id/ENSGALT00010068556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042164.1", "url": "https://www.ensembl.org/id/ENSGALP00010042164.1" } ] } }, { "isoform_ac": "A0A8V1AFX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14/entry#A0A8V1AFX4-1", "sequence": { "sequence": "CFPGLGTCLPIHPNLVMCFCVFLDSERSHLSSFTMKLKGKFHSPKIKRTPSKKGKQADLTVKTPEKSANKVSKWRASSPRLTGFLLSVTQVLRSTALLSVCDFNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQSDPRIQQSSAISSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKDVIKAVLDGVKELVKLTIEKQEHPSPTSPVKPSLPACKSDSPSELPLTDREMEILNKTTNMTQSNELLTDSMDEEVAPPKPPLPCIRVAENSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQVPTTLSPLPESLGESGSPFHGHAFQLPQGSSSPLEFCSLSGAVQPTETPPALPEKKRRSAASQTSDSSCRVSYERHPSQYDNISEDDMQNAGSLSSVPCTPFAPILPFQQGNSSAQVEFIADFAAPDSNSDPEKPPPLPEKKNKHMMAYMQFVEDYSEPQPSMFYQTPQNEHIYQQKNKHLMEVYGFNDSFISLDPSQDLAPPPALPPKQRQLQASYAASSFPSVSYCVQQTKVPFTPEDTGAAQGLTMSVSNSFLNRHSSFPVHSYKSVFRSYSQDFVPHNQVSVPPFLSSTSSSCSTAPFPPVHPSPSSDLAVPATASPSPSTGDVPNSSSQESSFNGSAPVCLPSETSLTDSLQTPSESPSVKDGHSKDSTSNSSAMGKEGKDGAERQQQSPDALESSQLEEEVDELSLIDHSEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFITPEELIKKLHKNTFFVLVRVVDELCLVELTEEILKLLMDLVFRLVCNGELSLARVLRKNILDKVDQKKMLRYANSIKPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQDLTFVHLGNPDYIDSKVNFSKRWQQFNILDSMRCFQQVHYDIKRNDDIVSFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT", "length": 1222, "header": "tr|A0A8V1AFX4-1|A0A8V1AFX4_CHICK Computationally mapped isoform of CRK SH3-binding GNRP OS=Gallus gallus OX=9031 GN=RAPGEF1 PE=4 SV=1 CANONICAL=A0A8V1AK14-1" }, "locus": { "chromosome": "17", "start_pos": 6896526, "end_pos": 6848514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068544.1", "url": "https://www.ensembl.org/id/ENSGALT00010068544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042156.1", "url": "https://www.ensembl.org/id/ENSGALP00010042156.1" } ] } }, { "isoform_ac": "A0A8V1AI70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14/entry#A0A8V1AI70-1", "sequence": { "sequence": "QDTNSERSHLSSFTMKLKGKFHSPKIKRTPSKKGKQADLTVKTPEKSANKVSKWRASSPRLTGFLLSVTQVLRSTALLSVCDFNLSWLEEKEKEVVSALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQSDPRIQQSSAISSCYSRVYQSLANLIRWSDQVMLEGVNSEDKEMVTTVKDVIKAVLDGVKELVKLTIEKQEHPSPTSPVKPSLPACKSDSPSELPLTDREMEILNKTTNMTQSNELLTDSMDEEVAPPKPPLPCIRVAENSPPPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGGESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQIPQQVPTTLSPLPESLGESGSPFHGHAFQLPQGSSSPLEFCSLSGAVQPTETPPALPEKKRRSAASQTSDSSCRVSYERHPSQYDNISEDDMQNAGSLSSVPCTPFAPILPFQQGNSSAQVEFIADFAAPDSNSDPEKPPPLPEKKNKHMMAYMQFVEDYSEPQPSMFYQTPQNEHIYQQKNKHLMEVYGFNDSFISLDPSQDLAPPPALPPKQRQLVTLPAGLLCKPRAQVDPASLCHQGGDDTDGCLPVFYRQQQSPDALESSQLEEEVDELSLIDHSEIMARLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFITPEELIKKLHKNTFFVLVRVVDELCLVELTEEILKLLMDLVFRLVCNGELSLARVLRKNILDKVDQKKMLRYANSIKPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEGLAEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQDLTFVHLGNPDYIDSKVNFSKRWQQFNILDSMRCFQQVHYDIKRNDDIVSFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT", "length": 1062, "header": "tr|A0A8V1AI70-1|A0A8V1AK14_CHICK Computationally mapped isoform of CRK SH3-binding GNRP OS=Gallus gallus OX=9031 GN=RAPGEF1 PE=4 SV=1 CANONICAL=A0A8V1AK14-1" }, "locus": { "chromosome": "17", "start_pos": 6896481, "end_pos": 6848514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068541.1", "url": "https://www.ensembl.org/id/ENSGALT00010068541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042155.1", "url": "https://www.ensembl.org/id/ENSGALP00010042155.1" } ] } }, { "isoform_ac": "A0A8V1AK14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK14/entry#A0A8V1AK14-1", "sequence": { "sequence": 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homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "xenobiotic catabolic process", "id": "GO:0042178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ], "pmid": "" }, { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ], "pmid": "" }, { "name": "nitrobenzene metabolic process", "id": "GO:0018916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018916", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ], "pmid": "" }, { "name": "cellular detoxification of nitrogen compound", "id": "GO:0070458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070458", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI83", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P20135-1", "Q08393-1", "A0A8V1AI83-1", "A0A8V0ZJE0-1", "A0A8V0XB81-1", "A0A1D5PN41-1", "A0A8V0XH39-1", "E1BUB6-1", "O73888-1", "A0A1D5NT70-1" ], "evidence": [ { "id": "R-GGA-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-176054" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NT70", "gene_name": "LOC395611", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A1D5NT70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A1D5NT70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NT70" } ] } ] }, { "uniprot_ac": "A0A1D5PN41", "gene_name": "GSTZ1", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "5.2.1.2", "activity": "", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A1D5PN41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN41" } ] } ] }, { "uniprot_ac": "A0A8V0XB81", "gene_name": "GSTA4", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0XB81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB81" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0XB81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB81" } ] } ] }, { "uniprot_ac": "A0A8V0XH39", "gene_name": "LOC100859645", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0XH39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH39" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0XH39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH39" } ] } ] }, { "uniprot_ac": "A0A8V0ZJE0", "gene_name": "GSTO2", "activity": [ { "ec_number": "1.20.4.2", "activity": "methylarsonate + 2 glutathione + H(+) = methylarsonous acid + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.8.5.1", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] }, { "ec_number": "1.20.4.2", "activity": "", "evidence": [ { "id": "A0A8V0ZJE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE0" } ] } ] }, { "uniprot_ac": "A0A8V1AI83", "gene_name": "LOC107050492", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V1AI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V1AI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI83" } ] } ] }, { "uniprot_ac": "E1BUB6", "gene_name": "GSTT1L", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1BUB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUB6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1BUB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUB6" } ] } ] }, { "uniprot_ac": "O73888", "gene_name": "HPGDS", "activity": [ { "ec_number": "5.3.99.2", "activity": "prostaglandin H2 = prostaglandin D2.", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] }, { "ec_number": "5.3.99.2", "activity": "", "evidence": [ { "id": "O73888", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O73888" } ] } ] }, { "uniprot_ac": "P20135", "gene_name": "GSTT1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted 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} ], "protein_names": [ { "name": "Rh family B glycoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V1AI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86/entry#names_and_taxonomy" } ] }, { "name": "Rhesus blood group, B glycoprotein", "type": "synonym", "evidence": [ { "id": "NP_989698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989698" } ] }, { "name": "ammonium transporter Rh type B", "type": "synonym", "evidence": [ { "id": "NP_989698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989698" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX935023.2, SRR13267659.309956.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. 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"https://www.reactome.org/PathwayBrowser/#R-GGA-444411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989698", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI86", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERAAARLHLSGLCFFLQLLTIVLFATFVRYSPESSNLCSTEPRCSQRDPSPTLGYPRFRDAHLRALLGFGFLLAFLSRYGVGSVAGSLLIVAFTIQWAILAQGLFYFSQNSKIYVSTQSMVSADFCTAAILISTGAVLGRVNPIQMLLMALLEVPLFACNEYILRSILGVSDSGGSLTIHTFGAYFGLTVSRALHQPHEDKRKEQQDVGHGPDVFAVVGTICLWIFWPSFASATTAHDSAEPWAVLNLYFSLAASTLATFILSPILYEEGTLQVAQLQDATLASTAVMGMAGEMLSTPFGALTAGFLASQLSLLSSRFLSPILRSRLKTEDTCGVHNVHGLPGILGTFLGTLLAALATADVFGDRLQLVFPLVADGSRTTAEQAQWQLCGLVVTLLLAALGGGLTGALLRTKVLRSPPERNELESKALREVDEDGCDHGTSSEERRTIA", "length": 451, "header": "tr|A0A8V1AI86-1|A0A8V1AI86_CHICK Isoform 1 of Rh family B glycoprotein OS=Gallus gallus OX=9031 GN=RHBG PE=3 SV=1 CANONICAL=A0A8V1AI86-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86/entry#A0A8V1ADB8-1", "sequence": { "sequence": "MAERAAARLHLSGLCFFLQLLTIVLFATFVRYSPESSNLCSTEPRCSQRDPSPTLGYPRFRDAHLRALLGFGFLLAFLSRYGVGSVAGSLLIVAFTIQWAILAQGLFYFSQNSKIYVSTQSMVSADFCTAAILISTGAVLGRVNPIQMLLMALLEVPLFACNEYILRSILGVSDSGGSLTIHTFGAYFGLTVSRALHQPHEDKRKEQQDVGHGPDVFAVVGTICLWIFWPSFASATTAHDSAEPWAVLNLYFSLAASTLATFILSPILYEEGTLQVAQLQDATLASTAVMGMAGEMLSTPFGALTAGFLASQLSLLSSRFLSPILRSRLKTEDTCGVHNVHGLPGILGTFLGTLLAALATADVFGDRLQLVFPLVADGSRTTAEQAQWQLCGLVVTLLLAALGGGLTGEFQPRALNIYIYIYRPQKPNETTKSDAERWSPRGAARPGGR", "length": 449, "header": "tr|A0A8V1ADB8-1|A0A8V1ADB8_CHICK Computationally mapped isoform of Rh family B glycoprotein OS=Gallus gallus OX=9031 GN=RHBG PE=3 SV=1 CANONICAL=A0A8V1AI86-1" }, "locus": { "chromosome": "25", "start_pos": 988921, "end_pos": 985372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068566.1", "url": "https://www.ensembl.org/id/ENSGALT00010068566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042169.1", "url": "https://www.ensembl.org/id/ENSGALP00010042169.1" } ] } }, { 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"spectrin-associated cytoskeleton", "id": "GO:0014731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI86", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ammonium channel activity", "id": "GO:0008519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI86", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86" } ], "pmid": "" }, { "name": "carbon dioxide transmembrane transporter activity", "id": "GO:0035379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI86", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86" } ], "pmid": "" }, { "name": "ankyrin binding", "id": "GO:0030506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI86", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI86" }, { "id": "PF00909", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00909" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ammonium transporter AmtB-like", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 412, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI87-1", "uniprot_ac": "A0A8V1AI87", "uniprot_id": "A0A8V1AI87_CHICK", "mass": { "chemical_mass": 13159.0, "monoisotopic_mass": 13159.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121111891", "type": "recommended", "evidence": [ { "id": "A0A8V1AI87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI87" } ] } ], "protein_names": [ { "name": "Pyroglutamylated RFamide peptide", "type": "synonym", "evidence": [ { "id": "A0A8V1AI87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI87/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI87", 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"categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-389397", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389397", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AI87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAPYSLTCLILLSLGACCPPHEHHEPRHPEDVLEPCWRGAVAEAVGPCGWAAPMRRRSEELGALLGIARVLRGYGQQHSVGPRGRPEGSEKRGGGGTLGDLAEELNGYGRKKGGFAFRFGR", "length": 122, "header": "tr|A0A8V1AI87-1|A0A8V1AI87_CHICK Isoform 1 of Pyroglutamylated RFamide peptide OS=Gallus gallus OX=9031 GN=LOC121111891 PE=3 SV=1 CANONICAL=A0A8V1AI87-1" }, "isoforms": [ { "isoform_ac": 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"https://www.uniprot.org/uniprotkb/A0A8V1AKF6/entry#A0A8V1AKF6-1", "sequence": { "sequence": "MHQGSFLLFHYYPDVLLEFISFSSVCFGTYVKKSQNPFPEAVNASSSMCRWSALVGVWPWCLLCPPEPCPRRLDCALQRRKFCPLGSSTCGPCLPNFLEDSHGHCLQEKRSPSGRTSVPSLEDEIDVLADVLARQDATRSHALRDGKPRTTLAPTGRQRVPSRLRQELLQRGPAGSKAAATLPTSTTATAPKYPVEAAPVPSNDDVVLGLIVVCTLAGISALIVAAVCWCRLQKEVRLAQKADYSAQRVASPLPYDKISPGDKTLAQSAQMYHYQHQKQQMLSMEKHKEEPKVPDSASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDDSSLHPPNPKVHP", "length": 343, "header": "tr|A0A8V1AKF6-1|A0A8V1AKF6_CHICK Isoform 1 of Neural proliferation, differentiation and control 1 OS=Gallus gallus OX=9031 GN=NPDC1 PE=1 SV=1 CANONICAL=A0A8V1AKF6-1" }, "locus": { "chromosome": "17", "start_pos": 1151374, "end_pos": 1143513, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070416.1", "url": "https://www.ensembl.org/id/ENSGALT00010070416.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043107.1", "url": "https://www.ensembl.org/id/ENSGALP00010043107.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AI99-1", "uniprot_ac": "A0A8V1AI99", "uniprot_id": "A0A8V1AI99_CHICK", "mass": { "chemical_mass": 149296.0, "monoisotopic_mass": 149296.0 }, "refseq": {}, "gene_names": [ { "name": "MYBBP1A", "type": "recommended", "evidence": [ { "id": "A0A8V1AI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ] } ], "protein_names": [ { "name": "MYB binding protein 1a", "type": "synonym", "evidence": [ { "id": "A0A8V1AI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYBBP1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99", "locus": { "chromosome": "19", "start_pos": 3423110, "end_pos": 3371266, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029423", "url": "https://www.ensembl.org/id/ENSGALG00010029423" } ] } } ], "crossref": [ { "id": "IPR007015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI99", "url": "https://www.orthodb.org/?gene=A0A8V1AI99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM61", "url": "https://www.orthodb.org/?gene=A0A8V1AM61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13213:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13213:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM61", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEREARHGGGVPADPRGVLRKGRAFLDLFWDIAKPEQEVRLAATENLLRHLRDGGEDEELKYALRRLVEGLGATREAARPGFSLALAQVLQAFEEIPLCSVLEQIQEKHNLEKVKKKLVRNAAFGNFFGVMALFQSGRLIKDQKALLESIQLLQQLAHHQTHLRDLPSKTLVDILSEVWPQPVVPETVFEEVLFGILQADLTSAFKSPENLHLLLVGMQKFPGVLKPKKLKKLFGSPTIVNEENIPRLVELLESAAKSEKKDKKLPSVGLDLLQVSLKEGAFELFWSEAVENGLFKEKSGPVSYMCYRLLGSALPLLSVDQLQMVLKGRVMQHYGEHVVTTQLPDRFKFAPEMEAYVDKFLTSCDDPERQLAVMIGFSTLTNQGYPVVPSVWRVVRHLQPVALQKYIDWLKDMFLKPDLGCCLDFSTNRQKQNQENKNIAQHKIARLRKWIIHRLMSIVESPVKKEESLVMDISRFCFFHAFFETKKKTSQIPETNALMSEPLDEQAHSLAANYFFGLLQTLNTLTVLGDTAEAAALREKHIHGVTADGKLWIFHLVEYASELLSSEKYVKAVKPFTKEQRDAWERSLQSVKNLQKKKSKSDSAKLFAFQQLLLLMAIHLFKNPSETMDLLSDLLNCTERAFSKEPKKKKTENAEPEWVEVIVEILLSLLAQPSLLIRRISNSVFGRICPNLTKKGLQLILDVLDPYQDQDEESAVVVVEESEKEKKSAQDTDDDESEDSSDDGDTEEENDSEDEKNEEVDEDFRSQLINVLQAGNAVGEDESDEELDDEAMMALDKSISALFAEQQKRIQAKKDEKDRIRKEKILRRDFKIKVLDLIEVFLSKQPENPLVFDIIEPLLQVIEQCMSSDSDKQEIDFLQKTAHIFTNSLCRAKQYCKRVDVLQDDLHTFVERLVKKACKHTDSSVALYYFSASLYLLKVLKGNVSDKSPALPVPLSKKQTDTIPQACQLLSTGCLDVERVTLIYQQALTQFLSKRNSALTSSMFLDLFTRFPIMCKPLIDILVKSITAGARQHQQAQACLLLQKVLPLRELKLSTTKEEWEELIRESISQVTESLKVADKLRVKAEKEKVARSLELLNFLLKTVTQQKLHVELMELDKVLVALNQQESIGKSARLDSLYWNVMRWLNYTKPKKEKTANKPVQEAEPLKRKKKGFLPETKKRKNRKKAVQENGAAPVASEDGDSAAPEEQPLGIETPEQKDGHLPGSKKHRKRNRGVRENGVAVEGSGNGAVNGGDAVAEKKKKKKRNRKRKGDVGNEAEQIPATKKAKGDVNQETQQKQGKAKKKRKEKKSAMLQE", "length": 1317, "header": "tr|A0A8V1AI99-1|A0A8V1AI99_CHICK Isoform 1 of MYB binding protein 1a OS=Gallus gallus OX=9031 GN=MYBBP1A PE=1 SV=1 CANONICAL=A0A8V1AI99-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AI99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99/entry#A0A8V1AI99-1", "sequence": { "sequence": "MAEREARHGGGVPADPRGVLRKGRAFLDLFWDIAKPEQEVRLAATENLLRHLRDGGEDEELKYALRRLVEGLGATREAARPGFSLALAQVLQAFEEIPLCSVLEQIQEKHNLEKVKKKLVRNAAFGNFFGVMALFQSGRLIKDQKALLESIQLLQQLAHHQTHLRDLPSKTLVDILSEVWPQPVVPETVFEEVLFGILQADLTSAFKSPENLHLLLVGMQKFPGVLKPKKLKKLFGSPTIVNEENIPRLVELLESAAKSEKKDKKLPSVGLDLLQVSLKEGAFELFWSEAVENGLFKEKSGPVSYMCYRLLGSALPLLSVDQLQMVLKGRVMQHYGEHVVTTQLPDRFKFAPEMEAYVDKFLTSCDDPERQLAVMIGFSTLTNQGYPVVPSVWRVVRHLQPVALQKYIDWLKDMFLKPDLGCCLDFSTNRQKQNQENKNIAQHKIARLRKWIIHRLMSIVESPVKKEESLVMDISRFCFFHAFFETKKKTSQIPETNALMSEPLDEQAHSLAANYFFGLLQTLNTLTVLGDTAEAAALREKHIHGVTADGKLWIFHLVEYASELLSSEKYVKAVKPFTKEQRDAWERSLQSVKNLQKKKSKSDSAKLFAFQQLLLLMAIHLFKNPSETMDLLSDLLNCTERAFSKEPKKKKTENAEPEWVEVIVEILLSLLAQPSLLIRRISNSVFGRICPNLTKKGLQLILDVLDPYQDQDEESAVVVVEESEKEKKSAQDTDDDESEDSSDDGDTEEENDSEDEKNEEVDEDFRSQLINVLQAGNAVGEDESDEELDDEAMMALDKSISALFAEQQKRIQAKKDEKDRIRKEKILRRDFKIKVLDLIEVFLSKQPENPLVFDIIEPLLQVIEQCMSSDSDKQEIDFLQKTAHIFTNSLCRAKQYCKRVDVLQDDLHTFVERLVKKACKHTDSSVALYYFSASLYLLKVLKGNVSDKSPALPVPLSKKQTDTIPQACQLLSTGCLDVERVTLIYQQALTQFLSKRNSALTSSMFLDLFTRFPIMCKPLIDILVKSITAGARQHQQAQACLLLQKVLPLRELKLSTTKEEWEELIRESISQVTESLKVADKLRVKAEKEKVARSLELLNFLLKTVTQQKLHVELMELDKVLVALNQQESIGKSARLDSLYWNVMRWLNYTKPKKEKTANKPVQEAEPLKRKKKGFLPETKKRKNRKKAVQENGAAPVASEDGDSAAPEEQPLGIETPEQKDGHLPGSKKHRKRNRGVRENGVAVEGSGNGAVNGGDAVAEKKKKKKRNRKRKGDVGNEAEQIPATKKAKGDVNQETQQKQGKAKKKRKEKKSAMLQE", "length": 1317, "header": "tr|A0A8V1AI99-1|A0A8V1AI99_CHICK Isoform 1 of MYB binding protein 1a OS=Gallus gallus OX=9031 GN=MYBBP1A PE=1 SV=1 CANONICAL=A0A8V1AI99-1" }, "locus": { "chromosome": "19", "start_pos": 3422024, "end_pos": 3371297, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071180.1", "url": "https://www.ensembl.org/id/ENSGALT00010071180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043871.1", "url": "https://www.ensembl.org/id/ENSGALP00010043871.1" } ] } }, { "isoform_ac": "A0A8V1AM61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99/entry#A0A8V1AM61-1", "sequence": { "sequence": "MAEREARHGGGVPADPRGVLRKGRAFLDLFWDIAKPEQEVRLAATENLLRHLRDGGEDEELKYALRRLVEGLGATREAARPGFSLALAQVLQAFEEIPLCSVLEQIQEKHNLEKVKKKLVRNAAFGNFFGVMALFQSGRLIKDQKALLESIQLLQQLAHHQTHLRDLPSKTLVDILSEVPETVFEEVLFGILQADLTSAFKSPENLHLLLVGMQKFPGVLKPKKLKKLFGSPTIVNEENIPRLVELLESAAKSEKKDKKLPSVGLDLLQVSLKEGAFELFWSEAVENGLFKEKSGPVSYMCYRLLGSALPLLSVDQLQMVLKGRVMQHYGEHVVTTQLPDRFKFAPEMEAYVDKFLTSCDDPERQLAVMIGFSTLTNQGYPVVPSVWRVVRHLQPVALQKYIDWLKDMFLKPDLGCCLDFSTNRQKQNQENKNIAQHKIARLRKWIIHRLMSIVESPVKKEESLVMDISRFCFFHAFFETKKKTSQIPETNALMSEPLDEQAHSLAANYFFGLLQTLNTLTVLGDTAEAAALREKHIHGVTADGKLWIFHLVEYASELLSSEKYVKAVKPFTKEQRDAWERSLQSVKNLQKKKSKSDSAKLFAFQQLLLLMAIHLFKNPSETMDLLSDLLNCTERAFSKEPKKKKTENAEPEWVEVIVEILLSLLAQPSLLIRRISNSVFGRICPNLTKKGLQLILDVLDPYQDQDEESAVVVVEESEKEKKSAQDTDDDESEDSSDDGDTEEENDSEDEKNEEVDEDFRSQLINVLQAGNAVGEDESDEELDDEAMMALDKSISALFAEQQKRIQAKKDEKDRIRKEKILRRDFKIKVLDLIEVFLSKQPENPLVFDIIEPLLQVIEQCMSSDSDKQEIDFLQKTAHIFTNSLCRAKQYCKRVDVLQDDLHTFVERLVKKACKHTDSSVALYYFSASLYLLKVLKGNVSDKSPALPVPLSKKQTDTIPQACQLLSTGCLDVERVTLIYQQALTQFLSKRNSALTSSMFLDLFTRFPIMCKPLIDILVKSITAGARQHQQAQACLLLQKVLPLRELKLSTTKEEWEELIRESISQVTESLKVADKLRVKAEKEKVARSLELLNFLLKTVTQQKLHVELMELDKVLVALNQQESIGKSARLDSLYWNVMRWLNYTKPKKEKTANKPVQEAEPLKRKKKGFLPETKKLCQDSRLCAASSLPSSPRPADHHAPGSWTCRAEAEQRTQELGCFCSAFGFLPAGGSVLHHMGKGKGNVMLVAKGCVCPWLFMCLCNVFSQMA", "length": 1267, "header": "tr|A0A8V1AM61-1|A0A8V1AM61_CHICK Computationally mapped isoform of MYB binding protein 1a OS=Gallus gallus OX=9031 GN=MYBBP1A PE=1 SV=1 CANONICAL=A0A8V1AI99-1" }, "locus": { "chromosome": "19", "start_pos": 3422945, "end_pos": 3371297, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071181.1", "url": "https://www.ensembl.org/id/ENSGALT00010071181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043872.1", "url": "https://www.ensembl.org/id/ENSGALP00010043872.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "NLS-dependent protein nuclear import complex", "id": "GO:0042564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "positive regulation of anoikis", "id": "GO:2000210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000210", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI99", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI99" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQETNQTQVPLLCTTGCGFYGSPRTNGMCSVCYKEFLQRQQSSDRISPPAASSPSSSPVASDSIAGQRAEEDSTAEDAKASAQTPVTHQMTAMSISREEGSSEAEGLAKTEEATPASSSSGTLLETSQSAAEDKTSPEKPKQKKNRCFTCRKKIGLTGETLTMGTAVCSPSSLQTDRLPELRGLAWLSAWGYPSKKCFGSASCADGKGTDCSSPCQPLNSGLQNCMEQCLSGYFCSLAEAVCGNTGSVHCRSNCSPIQGSGKALALLM", "length": 269, "header": "tr|A0A8V1AIA9-1|A0A8V1AIA9_CHICK Isoform 1 of A20-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC426626 PE=4 SV=1 CANONICAL=A0A8V1AIA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A691-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9/entry#A0A8V1A691-1", "sequence": { "sequence": "MAQETNQTQVPLLCTTGCGFYGSPRTNGMCSVCYKEFLQRQQSSDRISPPAASSPSSSPVASDSIAGQRAEEDSTAEDAKASAQTPVTHQMTAMSISREEGSSEAEGLAKTEEATPASSSSGTLLETSQSAAEDKTSPEKPKQKKNRCFTCRKKIGLTGFDCRCGNLFCAIHRYSDMHACPYDYKAEAAEKIRKENPVVIAEKIQKL", "length": 207, "header": "tr|A0A8V1A691-1|A0A8V1A691_CHICK Computationally mapped isoform of AN1-type zinc finger protein 5-like OS=Gallus gallus OX=9031 GN=LOC426626 PE=4 SV=1 CANONICAL=A0A8V1AIA9-1" }, "locus": { "chromosome": "28", "start_pos": 2651907, "end_pos": 2647874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067691.1", "url": "https://www.ensembl.org/id/ENSGALT00010067691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041434.1", "url": "https://www.ensembl.org/id/ENSGALP00010041434.1" } ] } }, { "isoform_ac": "A0A8V1ADX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9/entry#A0A8V1ADX3-1", "sequence": { "sequence": "MCVLSGGTRVALCFWHLGGGRMAQETNQTQVPLLCTTGCGFYGSPRTNGMCSVCYKEFLQRQQSSDRISPPAASSPSSSPVASDSIAGQRAEEDSTAEDAKASAQTPVTHQMTAMSISREEGSSEAEGLAKTEEATPASSSSGTLLETSQSAAEDKTSPEKPKQKKNRCFTCRKKIGLTGFDCRCGNLFCAIHRYSDMHACPYDYKAEAAEKIRKENPVVIAEKIQKL", "length": 228, "header": "tr|A0A8V1ADX3-1|A0A8V1ADX3_CHICK Computationally mapped isoform of AN1-type zinc finger protein 5 OS=Gallus gallus OX=9031 GN=LOC426626 PE=4 SV=1 CANONICAL=A0A8V1AIA9-1" }, "locus": { "chromosome": "28", "start_pos": 2651907, "end_pos": 2647720, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067690.1", "url": "https://www.ensembl.org/id/ENSGALT00010067690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041433.1", "url": "https://www.ensembl.org/id/ENSGALP00010041433.1" } ] } }, { "isoform_ac": "A0A8V1AIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9/entry#A0A8V1AIA9-1", "sequence": { "sequence": "MAQETNQTQVPLLCTTGCGFYGSPRTNGMCSVCYKEFLQRQQSSDRISPPAASSPSSSPVASDSIAGQRAEEDSTAEDAKASAQTPVTHQMTAMSISREEGSSEAEGLAKTEEATPASSSSGTLLETSQSAAEDKTSPEKPKQKKNRCFTCRKKIGLTGETLTMGTAVCSPSSLQTDRLPELRGLAWLSAWGYPSKKCFGSASCADGKGTDCSSPCQPLNSGLQNCMEQCLSGYFCSLAEAVCGNTGSVHCRSNCSPIQGSGKALALLM", "length": 269, "header": "tr|A0A8V1AIA9-1|A0A8V1AIA9_CHICK Isoform 1 of A20-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC426626 PE=4 SV=1 CANONICAL=A0A8V1AIA9-1" }, "locus": { "chromosome": "28", "start_pos": 2650690, "end_pos": 2647874, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067692.1", "url": "https://www.ensembl.org/id/ENSGALT00010067692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041435.1", "url": "https://www.ensembl.org/id/ENSGALP00010041435.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426626", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426626", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QGJ3-1", "protein_name": "Perilipin", "gene_name": "plin3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADNVKTAEKDKEDSQEQQSVISRVGNLPLVSSACGAVYNAYSSTKDSVPLLKGVMEVAESGVRTLGAAASTGSKPILDRLEPQIAAVNEYAIKGLEKVEGNLPILQQPADKLVSDTVGMVYQSVTGAKDAVVGAVMEGVEKTRMAVTGGINTVMGSRVGQMVSNGVDKALTHSEDWVEQNLPISEKELATLAEPRPGEEEGFIVSTRSSYFVRLGKLSAKVRERALEQSLLRARKARDTTHASVTQMTSTMDLLESARVTLTSANQQLAGAPEQLLQRWKEWKEGQPKELQEKVTAETEADGAKDKEQEMESKALLMVRGLSDQLKTACSGVVSSVQGLPGTVQEQLLNARRTAGELQASLSGTKTLTPVLLLQTRQQIGQVRQSLDGVVEYLLNNTPLNWLVGPFAPQITEKGE", "length": 416 }, "evidence": [ { "id": "A0A8V1AIA9", "url": "https://omabrowser.org/oma/group/A0A8V1AIA9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA9" }, { "id": "PS51036", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A20-type", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 42, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 115 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AID0-1", "uniprot_ac": "A0A8V1AID0", "uniprot_id": "A0A8V1AID0_CHICK", "mass": { "chemical_mass": 23721.0, "monoisotopic_mass": 23721.0 }, "refseq": {}, "gene_names": [ { "name": "RBM18", "type": "recommended", "evidence": [ { "id": "A0A8V1AID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0" } ] } ], "protein_names": [ { "name": "Probable RNA-binding protein 18", "type": "recommended", "evidence": [ { "id": "A0A8V1AID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 18", "type": "synonym", "evidence": [ { "id": "A0A8V1AID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AID0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBM18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0", "locus": { "chromosome": "17", "start_pos": 9343108, "end_pos": 9353882, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028355", "url": "https://www.ensembl.org/id/ENSGALG00010028355" } ] } } ], "crossref": [ { "id": "A0A8V1AID0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AID0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12355", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12355", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADH0", "url": "https://www.orthodb.org/?gene=A0A8V1ADH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AID0", "url": "https://www.orthodb.org/?gene=A0A8V1AID0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK69", "url": "https://www.orthodb.org/?gene=A0A8V1AK69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AID0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AID0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRGGPAPPWSRNDRRCRWRMPPSCPRAPCRTGTASGSATSTPRSPSERAGGCATEWRYHLLKLLQKFGKVKQFDFLFHKSGALEGQPRGYCFVNFETKQEAEKAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNEKILPISLEPSSSTEPPQSNLSVSAKIKAIEAKLKMMAENPDAEYPAAPVYSYFKPPEKKRTTPYSRAAWKSRR", "length": 210, "header": "tr|A0A8V1AID0-1|A0A8V1AID0_CHICK Isoform 1 of Probable RNA-binding protein 18 OS=Gallus gallus OX=9031 GN=RBM18 PE=4 SV=1 CANONICAL=A0A8V1AID0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0/entry#A0A8V1ADH0-1", "sequence": { "sequence": "INPRLPFREQPITAIKHWGVNRYHLLKLLQKFGKVKQFDFLFHKSGALEGQPRGYCFVNFETKQEAEKAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNEKILPISLEPSSSTEPPQSNLSVSAKIKAIEAKLKMMAENPDAEYPAAPVYSYFKPPEKKRTTPYSRAAWKSRR", "length": 174, "header": "tr|A0A8V1ADH0-1|A0A8V1ADH0_CHICK Computationally mapped isoform of Probable RNA-binding protein 18 OS=Gallus gallus OX=9031 GN=RBM18 PE=4 SV=1 CANONICAL=A0A8V1AID0-1" }, "locus": { "chromosome": "17", "start_pos": 9352165, "end_pos": 9344846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068690.1", "url": "https://www.ensembl.org/id/ENSGALT00010068690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042214.1", "url": "https://www.ensembl.org/id/ENSGALP00010042214.1" } ] } }, { "isoform_ac": "A0A8V1AID0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0/entry#A0A8V1AID0-1", "sequence": { "sequence": "MVRGGPAPPWSRNDRRCRWRMPPSCPRAPCRTGTASGSATSTPRSPSERAGGCATEWRYHLLKLLQKFGKVKQFDFLFHKSGALEGQPRGYCFVNFETKQEAEKAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNEKILPISLEPSSSTEPPQSNLSVSAKIKAIEAKLKMMAENPDAEYPAAPVYSYFKPPEKKRTTPYSRAAWKSRR", "length": 210, "header": "tr|A0A8V1AID0-1|A0A8V1AID0_CHICK Isoform 1 of Probable RNA-binding protein 18 OS=Gallus gallus OX=9031 GN=RBM18 PE=4 SV=1 CANONICAL=A0A8V1AID0-1" }, "locus": { "chromosome": "17", "start_pos": 9353861, "end_pos": 9344846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068691.1", "url": "https://www.ensembl.org/id/ENSGALT00010068691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042215.1", "url": "https://www.ensembl.org/id/ENSGALP00010042215.1" } ] } }, { "isoform_ac": "A0A8V1AK69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0/entry#A0A8V1AK69-1", "sequence": { "sequence": "MRVSLSPYFQSTERCHMSFPPPRYHLLKLLQKFGKVKQFDFLFHKSGALEGQPRGYCFVNFETKQEAEKAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNEKILPISLEPSSSTEPPQSNLSVSAKIKAIEAKLKMMAENPDAEYPAAPVYSYFKPPEKKRTTPYSRAAWKSRR", "length": 175, "header": "tr|A0A8V1AK69-1|A0A8V1AK69_CHICK Computationally mapped isoform of Probable RNA-binding protein 18 OS=Gallus gallus OX=9031 GN=RBM18 PE=4 SV=1 CANONICAL=A0A8V1AID0-1" }, "locus": { "chromosome": "17", "start_pos": 9349026, "end_pos": 9344846, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068689.1", "url": "https://www.ensembl.org/id/ENSGALT00010068689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042213.1", "url": "https://www.ensembl.org/id/ENSGALP00010042213.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AID0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AID0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AID0", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AID3-1", "uniprot_ac": "A0A8V1AID3", "uniprot_id": "A0A8V1AID3_CHICK", "mass": { "chemical_mass": 32415.0, "monoisotopic_mass": 32415.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121106516", "type": "recommended", "evidence": [ { "id": "A0A8V1AID3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3" } ] } ], "protein_names": [ { "name": "Borealin N-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AID3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AID3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106516", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3", "locus": {} } ], "crossref": [ { "id": "A0A8V1AID3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AID3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AID3", "url": "https://www.orthodb.org/?gene=A0A8V1AID3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10444", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10444", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AID3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AID3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENLYDVELLRLPAALREMNWLEFFGDADRASGAPGGTWLEVWRHMPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 300, "header": "tr|A0A8V1AID3-1|A0A8V1AID3_CHICK Isoform 1 of Borealin N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106516 PE=4 SV=1 CANONICAL=A0A8V1AID3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AID3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3/entry#A0A8V1AID3-1", "sequence": { "sequence": "MENLYDVELLRLPAALREMNWLEFFGDADRASGAPGGTWLEVWRHMPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 300, "header": "tr|A0A8V1AID3-1|A0A8V1AID3_CHICK Isoform 1 of Borealin N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106516 PE=4 SV=1 CANONICAL=A0A8V1AID3-1" }, "locus": { "chromosome": "19", "start_pos": 60964, "end_pos": 56523, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071215.1", "url": "https://www.ensembl.org/id/ENSGALT00010071215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043906.1", "url": "https://www.ensembl.org/id/ENSGALP00010043906.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 148, "start_aa": "Thr", "end_pos": 148, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr148", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AID3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AID3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID3" }, { "id": "PF10444", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Borealin N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 25, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 148 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AID4-1", "uniprot_ac": "A0A8V1AID4", "uniprot_id": "A0A8V1AID4_CHICK", "mass": { "chemical_mass": 49317.0, "monoisotopic_mass": 49317.0 }, "refseq": { "ac": "XP_414312", "name": "haloacid dehalogenase-like hydrolase domain-containing 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414312" }, "gene_names": [ { "name": "CECR5L", "type": "recommended", "evidence": [ { "id": "A0A8V1AID4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID4" } ] }, { "name": "CECR5L", "type": "synonym", "evidence": [ { "id": "XP_414312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414312" } ] } ], "protein_names": [ { "name": "Haloacid dehalogenase-like hydrolase domain-containing 5", "type": "recommended", "evidence": [ { "id": "A0A8V1AID4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AID4/entry#names_and_taxonomy" } ] }, { "name": "haloacid dehalogenase-like hydrolase domain-containing 5", "type": "synonym", "evidence": [ { "id": "XP_414312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414312" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_414312.2. 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This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135383.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135383" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM104A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE4", "locus": { "chromosome": "18", "start_pos": 9618677, "end_pos": 9628072, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029477", "url": "https://www.ensembl.org/id/ENSGALG00010029477" } ] } } ], "crossref": [ { "id": "A0A8V1AKE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "417450", 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] }, { "id": "A0A8V1AKE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCRQPLPSERGARQRKRRRNGNEEDSHIPQTKRSTRNTVLQDSWDTESKCVTECAPQPGEMKVAVTKNSKEHRLKGNKVSCASSSSDSGSSSSSCSSSSINSPDRASGSEPSLNPIVTGSSPVSSQSFHEQSALSQGPYFHINQILKEAHFHSLQSRGRPPT", "length": 163, "header": "tr|A0A8V1AKE4-1|A0A8V1AKE4_CHICK Isoform 1 of Family with sequence similarity 104 member A OS=Gallus gallus OX=9031 GN=FAM104A PE=4 SV=1 CANONICAL=A0A8V1AKE4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE4/entry#A0A8V1AIJ7-1", "sequence": { "sequence": "MSCRQPLPSERGARQRKRRRNGNEEDSHIPQTKRSTRNTVLQDSWDTESKCVTECAPQPGEMSSSSDSGSSSSSCSSSSINSPDRASGSEPSLNPIVTGSSPVSSQSFHEQSALSQGPYFHINQILKEAHFHSLQSRGRPPT", "length": 142, "header": "tr|A0A8V1AIJ7-1|A0A8V1AKE4_CHICK Computationally mapped isoform of Family with sequence similarity 104 member A OS=Gallus gallus OX=9031 GN=FAM104A PE=4 SV=1 CANONICAL=A0A8V1AKE4-1" }, "locus": { "chromosome": "18", "start_pos": 9627936, "end_pos": 9621101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071280.1", "url": "https://www.ensembl.org/id/ENSGALT00010071280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043971.1", "url": "https://www.ensembl.org/id/ENSGALP00010043971.1" } ] } }, { "isoform_ac": "A0A8V1AKE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE4/entry#A0A8V1AKE4-1", "sequence": { "sequence": "MSCRQPLPSERGARQRKRRRNGNEEDSHIPQTKRSTRNTVLQDSWDTESKCVTECAPQPGEMKVAVTKNSKEHRLKGNKVSCASSSSDSGSSSSSCSSSSINSPDRASGSEPSLNPIVTGSSPVSSQSFHEQSALSQGPYFHINQILKEAHFHSLQSRGRPPT", "length": 163, "header": "tr|A0A8V1AKE4-1|A0A8V1AKE4_CHICK Isoform 1 of Family with sequence similarity 104 member A OS=Gallus gallus OX=9031 GN=FAM104A PE=4 SV=1 CANONICAL=A0A8V1AKE4-1" }, "locus": { "chromosome": "18", "start_pos": 9627936, "end_pos": 9621101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071277.1", "url": "https://www.ensembl.org/id/ENSGALT00010071277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043968.1", "url": "https://www.ensembl.org/id/ENSGALP00010043968.1" } ] } }, { "isoform_ac": "A0A8V1AMC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE4/entry#A0A8V1AMC4-1", "sequence": { "sequence": "MAKQALWREEEEFSVEQGIEMGVMKLRISGKTFMKVAVTKNSKEHRLKGNKVSCASSSSDSGSSSSSCSSSSINSPDRASGSEPSLNPIVTGSSPVSSQSFHEQSALSQGPYFHINQILKEAHFHSLQSRGRPPT", "length": 135, "header": "tr|A0A8V1AMC4-1|A0A8V1AMC4_CHICK Computationally mapped isoform of Family with sequence similarity 104 member A OS=Gallus gallus OX=9031 GN=FAM104A PE=4 SV=1 CANONICAL=A0A8V1AKE4-1" }, "locus": { "chromosome": "18", "start_pos": 9625303, "end_pos": 9621101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071276.1", "url": "https://www.ensembl.org/id/ENSGALT00010071276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043967.1", "url": "https://www.ensembl.org/id/ENSGALP00010043967.1" } ] } }, { "isoform_ac": "A0A8V1ANW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE4/entry#A0A8V1ANW2-1", "sequence": { "sequence": "DSCKQDESNRVFIESVRRRNGNEEDSHIPQTKRSTRNTVLQDSWDTEKVAVTKNSKEHRLKGNKVSCASSSSDSGSSSSSCSSSSINSPDRASGSEPSLNPIVTGSSPVSSQSFHEQSALSQGPYFHINQILKEAHFHSLQSRGRPPT", "length": 148, "header": "tr|A0A8V1ANW2-1|A0A8V1ANW2_CHICK Computationally mapped isoform of Family with sequence similarity 104 member A OS=Gallus gallus OX=9031 GN=FAM104A PE=4 SV=1 CANONICAL=A0A8V1AKE4-1" }, "locus": { "chromosome": "18", "start_pos": 9626871, "end_pos": 9621101, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071274.1", "url": "https://www.ensembl.org/id/ENSGALT00010071274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043965.1", "url": "https://www.ensembl.org/id/ENSGALP00010043965.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5W4-1", "protein_name": "VCP nuclear cofactor family member 1", "gene_name": "VCF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGRGADAGSSGGTGPTEGYSPPAASTRAAARAKARGGGRGGRRNTTPSVPSSRGAAPRRSPPPAAMSERLRPRKRRRNGSEEDHHLPPQTKRSSRNAVFHDSWDTESSSSDSGGSSSSSINSPDRASGPESSFNHLASGSSPHTPQPVPEPSALCQGPYFHINQTLKEAHFHSLQHRGRPPT", "length": 183 }, "evidence": [ { "id": "A0A8V1AKE4", "url": "https://omabrowser.org/oma/group/A0A8V1AKE4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2A6P4-1", "protein_name": "VCP nuclear cofactor family member 1", "gene_name": "Vcf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRRGGDTGSGCGPGRPEGDSAPAATTRAAAVRAQTRAGGRGGRRDTAPTVRCRRGAAPRRSPSPAAMSERLRPRKRRRNGSDDDNHPPPQTKRSSRNPIFQDSWDTESSSSDSGGSSSSSSINSPDRASGPESSLSHTIPGSCPSTPQPMPEQSALCQGPYFHINQTLKEAHFHSLQHRGRPPT", "length": 185 }, "evidence": [ { "id": "A0A8V1AKE4", "url": "https://omabrowser.org/oma/group/A0A8V1AKE4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969W3-1", "protein_name": "Protein VCF1", "gene_name": "VCF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGRGADAGSSGGTGPTEGYSPPAASTRAAARAKARGGGRGGRRNTTPSVPSLRGAAPRSFHPPAAMSERLRPRKRRRNGNEEDNHLPPQTKRSSRNPVFQDSWDTESSGSDSGGSSSSSSSSINSPDRASGPEGSLSQTMAGSSPNTPQPVPEQSALCQGLYFHINQTLREAHFHSLQHRGRPLT", "length": 186 }, "evidence": [ { "id": "A0A8V1AKE4", "url": "https://omabrowser.org/oma/group/A0A8V1AKE4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKE0-1", "uniprot_ac": "A0A8V1AKE0", "uniprot_id": "A0A8V1AKE0_CHICK", "mass": { "chemical_mass": 17083.0, "monoisotopic_mass": 17083.0 }, "refseq": {}, "gene_names": [ { "name": "NR2C2AP", "type": "recommended", "evidence": [ { "id": "A0A8V1AKE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0" } ] } ], "protein_names": [ { "name": "Nuclear receptor 2C2-associated protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AKE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NR2C2AP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0", "locus": { "chromosome": "28", "start_pos": 4014788, "end_pos": 4010983, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028430", "url": "https://www.ensembl.org/id/ENSGALG00010028430" } ] } } ], "crossref": [ { "id": "A0A8V1AKE0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKE0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIK3", "url": "https://www.orthodb.org/?gene=A0A8V1AIK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKE0", "url": "https://www.orthodb.org/?gene=A0A8V1AKE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAEPLVCADTATRVSSVLNRDVKQFGKKHMFDANEETCWNSDQGSCQWVTLDFPRTVRVSQLHIQFQGGFSSRLCTLEGCRTGEELVKISDVYPEDINAMQISFAMLQAGGAVLFQVEETALDTLKITFENSIDFFGRIVVYHLQVLGERL", "length": 152, "header": "tr|A0A8V1AKE0-1|A0A8V1AKE0_CHICK Isoform 1 of Nuclear receptor 2C2-associated protein OS=Gallus gallus OX=9031 GN=NR2C2AP PE=1 SV=1 CANONICAL=A0A8V1AKE0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0/entry#A0A8V1AIK3-1", "sequence": { "sequence": "MPAEPLVCADTATRVSSVLNRDVKQFGKKHMFDANEETCWNSDQGSCQWVTLDFPRTVRVSQLHIQFQGGFSSRLCTLEGCRTGEELVKISDVYPEDINAMQIFQVEETALDTLKITFENSIDFFGRIVVYHLQVLGERL", "length": 140, "header": "tr|A0A8V1AIK3-1|A0A8V1AKE0_CHICK Computationally mapped isoform of Nuclear receptor 2C2-associated protein OS=Gallus gallus OX=9031 GN=NR2C2AP PE=1 SV=1 CANONICAL=A0A8V1AKE0-1" }, "locus": { "chromosome": "28", "start_pos": 4012062, "end_pos": 4011127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068861.1", "url": "https://www.ensembl.org/id/ENSGALT00010068861.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042303.1", "url": "https://www.ensembl.org/id/ENSGALP00010042303.1" } ] } }, { "isoform_ac": "A0A8V1AKE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0/entry#A0A8V1AKE0-1", "sequence": { "sequence": "MPAEPLVCADTATRVSSVLNRDVKQFGKKHMFDANEETCWNSDQGSCQWVTLDFPRTVRVSQLHIQFQGGFSSRLCTLEGCRTGEELVKISDVYPEDINAMQISFAMLQAGGAVLFQVEETALDTLKITFENSIDFFGRIVVYHLQVLGERL", "length": 152, "header": "tr|A0A8V1AKE0-1|A0A8V1AKE0_CHICK Isoform 1 of Nuclear receptor 2C2-associated protein OS=Gallus gallus OX=9031 GN=NR2C2AP PE=1 SV=1 CANONICAL=A0A8V1AKE0-1" }, "locus": { "chromosome": "28", "start_pos": 4012062, "end_pos": 4011127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068859.1", "url": "https://www.ensembl.org/id/ENSGALT00010068859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042301.1", "url": "https://www.ensembl.org/id/ENSGALP00010042301.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIK8-1", "uniprot_ac": "A0A8V1AIK8", "uniprot_id": "A0A8V1AIK8_CHICK", "mass": { "chemical_mass": 32254.0, "monoisotopic_mass": 32254.0 }, "refseq": { "ac": "XP_001233620", "name": "cdc42 effector protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233620" }, "gene_names": [ { "name": "CDC42EP4", "type": "recommended", "evidence": [ { "id": "A0A8V1AIK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK8" } ] }, { "name": "CDC42EP4", "type": "synonym", "evidence": [ { "id": "XP_001233620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233620" } ] } ], "protein_names": [ { "name": "CDC42 effector protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AIK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK8/entry#names_and_taxonomy" } ] }, { "name": "cdc42 effector protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233620" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233620.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233620" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC42EP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIK8", "locus": { "chromosome": "18", "start_pos": 9636352, "end_pos": 9644357, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029487", "url": "https://www.ensembl.org/id/ENSGALG00010029487" } ] } } ], "crossref": [ { "id": "771509", "url": "https://www.ncbi.nlm.nih.gov/gene/771509", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771509", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771509", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKYEYNM", "url": "https://omabrowser.org/oma/group/DKYEYNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIK8", "url": "https://www.orthodb.org/?gene=A0A8V1AIK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15344:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15344:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14957", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14957", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { 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"keywords": [], "publication": [], "pathway": [ { "id": "gga:771509", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771509", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WC33-1", "protein_name": "CDC42 effector protein 4", "gene_name": "Cdc42ep4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIN8-1", "uniprot_ac": "A0A8V1AIN8", "uniprot_id": "A0A8V1AIN8_CHICK", "mass": { "chemical_mass": 22125.0, "monoisotopic_mass": 22125.0 }, "refseq": {}, "gene_names": [ { "name": "C9orf142", "type": "recommended", "evidence": [ { "id": "A0A8V1AIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8" } ] } ], "protein_names": [ { "name": "PAXX non-homologous end joining factor", "type": "recommended", "evidence": [ { "id": "A0A8V1AIN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C9orf142", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR027873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIN8", "url": "https://www.orthodb.org/?gene=A0A8V1AIN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28586", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28586", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28586:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28586:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GAPSQPRPFPQRRPRLSHRPFRRCHGGAVGAFPSASGRSGPLPLLLPPRARPRLGRHRLVWAGRLGGDQPEDGVAELRAALGRGTVSLGLRDGAATLRLREGHEALLLPRLPAAEARPQLQALLFAMAARVRDLEERLEVLGTLSYSPEKNTPRSQQPILPDPSPRKNRAAGSALPVKRKIPGESLINPGFKSKSVPSGVDFEDS", "length": 205, "header": "tr|A0A8V1AIN8-1|A0A8V1AIN8_CHICK Isoform 1 of PAXX non-homologous end joining factor OS=Gallus gallus OX=9031 GN=C9orf142 PE=4 SV=1 CANONICAL=A0A8V1AIN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8/entry#A0A8V1AIN8-1", "sequence": { "sequence": "GAPSQPRPFPQRRPRLSHRPFRRCHGGAVGAFPSASGRSGPLPLLLPPRARPRLGRHRLVWAGRLGGDQPEDGVAELRAALGRGTVSLGLRDGAATLRLREGHEALLLPRLPAAEARPQLQALLFAMAARVRDLEERLEVLGTLSYSPEKNTPRSQQPILPDPSPRKNRAAGSALPVKRKIPGESLINPGFKSKSVPSGVDFEDS", "length": 205, "header": "tr|A0A8V1AIN8-1|A0A8V1AIN8_CHICK Isoform 1 of PAXX non-homologous end joining factor OS=Gallus gallus OX=9031 GN=C9orf142 PE=4 SV=1 CANONICAL=A0A8V1AIN8-1" }, "locus": { "chromosome": "17", "start_pos": 1090527, "end_pos": 1088895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067840.1", "url": "https://www.ensembl.org/id/ENSGALT00010067840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041583.1", "url": "https://www.ensembl.org/id/ENSGALP00010041583.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nonhomologous end joining complex", "id": "GO:0070419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070419", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIP1-1", "uniprot_ac": "A0A8V1AIP1", "uniprot_id": "A0A8V1AIP1_CHICK", "mass": { "chemical_mass": 32884.0, "monoisotopic_mass": 32884.0 }, "refseq": {}, "gene_names": [ { "name": "LOC430700", "type": "recommended", "evidence": [ { "id": "A0A8V1AIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1" } ] } ], "protein_names": [ { "name": "Fibrinogen C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC430700", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADA8", "url": "https://www.orthodb.org/?gene=A0A8V1ADA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIP1", "url": "https://www.orthodb.org/?gene=A0A8V1AIP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKI3", "url": "https://www.orthodb.org/?gene=A0A8V1AKI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWEGAPLGSCSLLSCAVVMGLQAGTHQLRGNLILLPVAVVMLLHCASAGPGMPTASSRSAPVESSPPLYRQGNVPFKTRAKVPVAGFPADCSHLRKTSPSGVYVIQPARSPPRVVWCDMDTEGKGWTVVQRNSHDTEIAWKQSWTTYKYGFGNVQGDHWLGTEYLHLLTQQGTYKVRFVVRDKANVTHYAEYDIFRVESESSGYPLRLGRYSGEGDDYLTGYYPKKGGIHDNMKFSTVDKDQDQYSGNCASSYGGWWYDRCQNVVLNAKKYILWPGFCDKGDCTSSLILVKPTDVC", "length": 297, "header": "tr|A0A8V1AIP1-1|A0A8V1AIP1_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430700 PE=4 SV=1 CANONICAL=A0A8V1AIP1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1/entry#A0A8V1ADA8-1", "sequence": { "sequence": "MLLHCASAGPGMPTASSRSVPVAGFPADCSHLRKTSPSGVYVIQPARSPPRVVWCDMDTEGKGWTVVQRNSHDTEIAWKQSWTTYKYGFGNVQGDHWLGTEYLHLLTQQGTYKVRFVVRDKANVTHYAEYDIFRVESESSGYPLRLGRYSGEGDDYLTGYYPKKGGIHDNMKFSTVDKDQDQYSGNCASSYGGWWYDRCQNVVLNAKKYILWPGFCDKGDCTSSLILVKPTDVC", "length": 234, "header": "tr|A0A8V1ADA8-1|A0A8V1ADA8_CHICK Computationally mapped isoform of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430700 PE=4 SV=1 CANONICAL=A0A8V1AIP1-1" }, "locus": { "chromosome": "19", "start_pos": 600095, "end_pos": 598417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071323.1", "url": "https://www.ensembl.org/id/ENSGALT00010071323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044014.1", "url": "https://www.ensembl.org/id/ENSGALP00010044014.1" } ] } }, { "isoform_ac": "A0A8V1AIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1/entry#A0A8V1AIP1-1", "sequence": { "sequence": "MAWEGAPLGSCSLLSCAVVMGLQAGTHQLRGNLILLPVAVVMLLHCASAGPGMPTASSRSAPVESSPPLYRQGNVPFKTRAKVPVAGFPADCSHLRKTSPSGVYVIQPARSPPRVVWCDMDTEGKGWTVVQRNSHDTEIAWKQSWTTYKYGFGNVQGDHWLGTEYLHLLTQQGTYKVRFVVRDKANVTHYAEYDIFRVESESSGYPLRLGRYSGEGDDYLTGYYPKKGGIHDNMKFSTVDKDQDQYSGNCASSYGGWWYDRCQNVVLNAKKYILWPGFCDKGDCTSSLILVKPTDVC", "length": 297, "header": "tr|A0A8V1AIP1-1|A0A8V1AIP1_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430700 PE=4 SV=1 CANONICAL=A0A8V1AIP1-1" }, "locus": { "chromosome": "19", "start_pos": 600824, "end_pos": 598417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071320.1", "url": "https://www.ensembl.org/id/ENSGALT00010071320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044011.1", "url": "https://www.ensembl.org/id/ENSGALP00010044011.1" } ] } }, { "isoform_ac": "A0A8V1AKI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1/entry#A0A8V1AKI3-1", "sequence": { "sequence": "MGGCTTGFLLSAQLCCCDGAAGWDTPAPWEPHPPARGGGDASPLCECSHLRKTSPSGVYVIQPARSPPRVVWCDMDTEGKGWTVVQRNSHDTEIAWKQSWTTYKYGFGNVQGDHWLGTEYLHLLTQQGTYKVRFVVRDKANVTHYAEYDIFRVESESSGYPLRLGRYSGEGDDYLTGYYPKKGGIHDNMKFSTVDKDQDQYSGNCASSYGGWWYDRCQNVVLNAKKYILWPGFCDKGDCTSSLILVKPTDVC", "length": 252, "header": "tr|A0A8V1AKI3-1|A0A8V1AKI3_CHICK Computationally mapped isoform of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC430700 PE=4 SV=1 CANONICAL=A0A8V1AIP1-1" }, "locus": { "chromosome": "19", "start_pos": 600819, "end_pos": 598417, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071322.1", "url": "https://www.ensembl.org/id/ENSGALT00010071322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044013.1", "url": "https://www.ensembl.org/id/ENSGALP00010044013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP1" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { 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"refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AIP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP3", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIP3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR036663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036663", "database": "InterPro", "categories": [ 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"protein_names": [ { "name": "Oxidoreductase-like domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OXLD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP5", "locus": { "chromosome": "18", "start_pos": 9776616, "end_pos": 9772372, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029506", "url": "https://www.ensembl.org/id/ENSGALG00010029506" } ] } } ], "crossref": [ { "id": "A0A8V1AIP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "427815", "url": "https://www.ncbi.nlm.nih.gov/gene/427815", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCVWVGY", "url": "https://omabrowser.org/oma/group/SCVWVGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIP5", "url": "https://www.orthodb.org/?gene=A0A8V1AIP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANZ3", "url": "https://www.orthodb.org/?gene=A0A8V1ANZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21193", "url": 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] } ], "sequence": { "sequence": "MWRGDAEGTGSVAEDYGFMQHPQGVRATMEGSYTMQEQQRRAPHPSAICSRRRRSDTPRSDCQTGTPRGEGETTRGAESPYPHPPELPPPTNCCMSGCHNCVWIEYVEQLLQHYGDGGERALAAVEQHVQDESIKAVLKLEIRLRMGTD", "length": 149, "header": "tr|A0A8V1AIP5-1|A0A8V1AIP5_CHICK Isoform 1 of Oxidoreductase-like domain containing 1 OS=Gallus gallus OX=9031 GN=OXLD1 PE=4 SV=1 CANONICAL=A0A8V1AIP5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP5/entry#A0A8V1AIP5-1", "sequence": { "sequence": "MWRGDAEGTGSVAEDYGFMQHPQGVRATMEGSYTMQEQQRRAPHPSAICSRRRRSDTPRSDCQTGTPRGEGETTRGAESPYPHPPELPPPTNCCMSGCHNCVWIEYVEQLLQHYGDGGERALAAVEQHVQDESIKAVLKLEIRLRMGTD", "length": 149, "header": "tr|A0A8V1AIP5-1|A0A8V1AIP5_CHICK Isoform 1 of Oxidoreductase-like domain containing 1 OS=Gallus gallus OX=9031 GN=OXLD1 PE=4 SV=1 CANONICAL=A0A8V1AIP5-1" }, "locus": { "chromosome": "18", "start_pos": 9775612, "end_pos": 9772389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071325.1", "url": "https://www.ensembl.org/id/ENSGALT00010071325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044016.1", "url": "https://www.ensembl.org/id/ENSGALP00010044016.1" } ] } }, { "isoform_ac": "A0A8V1ANZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP5/entry#A0A8V1ANZ3-1", "sequence": { "sequence": "MLLRAARGARGLAGRGREEQQRRAPHPSAICSRRRRSDTPRSDCQTGTPRGEGETTRGAESPYPHPPELPPPTNCCMSGCHNCVWIEYVEQLLQHYGDGGERALAAVEQHVQDESIKAVLKLEIRLRMGTD", "length": 131, "header": "tr|A0A8V1ANZ3-1|A0A8V1ANZ3_CHICK Computationally mapped isoform of Oxidoreductase-like domain containing 1 OS=Gallus gallus OX=9031 GN=OXLD1 PE=4 SV=1 CANONICAL=A0A8V1AIP5-1" }, "locus": { "chromosome": "18", "start_pos": 9775612, "end_pos": 9774727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071324.1", "url": "https://www.ensembl.org/id/ENSGALT00010071324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044015.1", "url": "https://www.ensembl.org/id/ENSGALP00010044015.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP5" }, { "id": "PF09791", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09791" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Oxidoreductase-like", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 110, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKU0-1", "uniprot_ac": "A0A8V1AKU0", "uniprot_id": "A0A8V1AKU0_CHICK", "mass": { "chemical_mass": 58909.0, "monoisotopic_mass": 58909.0 }, "refseq": { "ac": "XP_015150698", "name": "growth arrest-specific protein 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150698" }, "gene_names": [ { "name": "GAS7", "type": "recommended", "evidence": [ { "id": "A0A8V1AKU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ] }, { "name": "GAS7", "type": "synonym", "evidence": [ { "id": "XP_015150698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150698" } ] } ], "protein_names": [ { "name": "Growth arrest specific 7", "type": "synonym", "evidence": [ { "id": "A0A8V1AKU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#names_and_taxonomy" } ] }, { "name": "growth arrest-specific protein 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015150698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150698" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150698" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GAS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0", "locus": { "chromosome": "18", "start_pos": 824809, "end_pos": 931087, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029200", "url": "https://www.ensembl.org/id/ENSGALG00010029200" } ] } } ], "crossref": [ { "id": "A0A8V1AKU0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07649", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07649", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417305", "url": "https://www.ncbi.nlm.nih.gov/gene/417305", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RVEWVQQ", "url": "https://omabrowser.org/oma/group/RVEWVQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABA8", "url": "https://www.orthodb.org/?gene=A0A8V1ABA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABB2", "url": "https://www.orthodb.org/?gene=A0A8V1ABB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIP7", "url": "https://www.orthodb.org/?gene=A0A8V1AIP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIQ1", "url": "https://www.orthodb.org/?gene=A0A8V1AIQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKU0", "url": "https://www.orthodb.org/?gene=A0A8V1AKU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMI8", "url": "https://www.orthodb.org/?gene=A0A8V1AMI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMJ2", "url": "https://www.orthodb.org/?gene=A0A8V1AMJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16623", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16623", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSRCQTLYPFSGERHRQGLRFAAGELITVLQVPDGGWWEGQKEDGLRGWFPASYVQLLEQKPRKATPQPGEDTLNSHLPPGWQSYMSPQGRRYYVNTFTNETTWERPSSVPGTPKSPVTQQSPAVNGYHISGTPVHQLDSAHMNLRKASGDPQTPGSPAAPRRQSKESSLTINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRERIKIEEEYAKNLSKLSQNSLAAQEEGQSSLTVAQANRKIGHLWYRGLYLKLHCLENNFSDRKSTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 511, "header": "tr|A0A8V1AKU0-1|A0A8V1AKU0_CHICK Isoform 1 of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#A0A8V1ABA8-1", "sequence": { "sequence": "MEELQEVNSPLQKPRKATPQPGEDTLNSHLPPGWQSYMSPQGRRYYVNTFTNETTWERPSSVPGTPKSPVTQQSPAVNGYHISGTPVHQLDSAHMNLRKASGDPQINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRERIKIEEEYAKNLSKLSQNSLAAQEEGTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 406, "header": "tr|A0A8V1ABA8-1|A0A8V1ABA8_CHICK Computationally mapped isoform of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "locus": { "chromosome": "18", "start_pos": 895678, "end_pos": 828059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070565.1", "url": "https://www.ensembl.org/id/ENSGALT00010070565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043256.1", "url": "https://www.ensembl.org/id/ENSGALP00010043256.1" } ] } }, { "isoform_ac": "A0A8V1ABB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#A0A8V1ABB2-1", "sequence": { "sequence": "MSGSRCQTLYPFSGERHRQGLRFAAGELITVLQVPDGGWWEGQKEDGLRGWFPASYVQLLEKPRKATPQPGEDTLNSHLPPGWQSYMSPQGRRYYVNTFTNVNGYHISGTPVHQLDSAHMNLRKASGDPQTPGSPAAPRRQSKESSLTINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRERIKIEEEYAKNLSKLSQNSLAAQEEGTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 449, "header": "tr|A0A8V1ABB2-1|A0A8V1ABB2_CHICK Computationally mapped isoform of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "locus": { "chromosome": "18", "start_pos": 931007, "end_pos": 828059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070570.1", "url": "https://www.ensembl.org/id/ENSGALT00010070570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043261.1", "url": "https://www.ensembl.org/id/ENSGALP00010043261.1" } ] } }, { "isoform_ac": "A0A8V1AIP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#A0A8V1AIP7-1", "sequence": { "sequence": "MLGSECALDDAIRFSPQTPGSPAAPRRQSKESSLTINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRESTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 311, "header": "tr|A0A8V1AIP7-1|A0A8V1AKU0_CHICK Computationally mapped isoform of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "locus": { "chromosome": "18", "start_pos": 865618, "end_pos": 828059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070564.1", "url": "https://www.ensembl.org/id/ENSGALT00010070564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043255.1", "url": "https://www.ensembl.org/id/ENSGALP00010043255.1" } ] } }, { "isoform_ac": "A0A8V1AIQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#A0A8V1AIQ1-1", "sequence": { "sequence": "MNLHSSSVQQHDAYPLLFLMMCITPSELDHQQKPRKATPQPGEDTLNSHLPPGWQSYMSPQGRRYYVNTFTNETTWERPSSVPGTPKSPVTQQSPAVNGYHISGTPVHQLDSAHMNLRKASGDPQINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRERIKIEEEYAKNLSKLSQNSLAAQEEGTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 426, "header": "tr|A0A8V1AIQ1-1|A0A8V1AIQ1_CHICK Computationally mapped isoform of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "locus": { "chromosome": "18", "start_pos": 890819, "end_pos": 828059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070569.1", "url": "https://www.ensembl.org/id/ENSGALT00010070569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043260.1", "url": "https://www.ensembl.org/id/ENSGALP00010043260.1" } ] } }, { "isoform_ac": "A0A8V1AKU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#A0A8V1AKU0-1", "sequence": { "sequence": "MSGSRCQTLYPFSGERHRQGLRFAAGELITVLQVPDGGWWEGQKEDGLRGWFPASYVQLLEQKPRKATPQPGEDTLNSHLPPGWQSYMSPQGRRYYVNTFTNETTWERPSSVPGTPKSPVTQQSPAVNGYHISGTPVHQLDSAHMNLRKASGDPQTPGSPAAPRRQSKESSLTINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRERIKIEEEYAKNLSKLSQNSLAAQEEGQSSLTVAQANRKIGHLWYRGLYLKLHCLENNFSDRKSTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 511, "header": "tr|A0A8V1AKU0-1|A0A8V1AKU0_CHICK Isoform 1 of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "locus": { "chromosome": "18", "start_pos": 931007, "end_pos": 828059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070568.1", "url": "https://www.ensembl.org/id/ENSGALT00010070568.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043259.1", "url": "https://www.ensembl.org/id/ENSGALP00010043259.1" } ] } }, { "isoform_ac": "A0A8V1AMI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#A0A8V1AMI8-1", "sequence": { "sequence": "MEECSCKPRKQMPLLLGAAVVVPHSCCPAACLPSGTERERSRGAAAMQKPRKATPQPGEDTLNSHLPPGWQSYMSPQGRRYYVNTFTNETTWERPSSVPGTPKSPVTQQSPAVNGYHISGTPVHQLDSAHMNLRKASGDPQTPGSPAAPRRQSKESSLTINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRERIKIEEEYAKNLSKLSQNSLAAQEEGTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 460, "header": "tr|A0A8V1AMI8-1|A0A8V1AMI8_CHICK Computationally mapped isoform of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "locus": { "chromosome": "18", "start_pos": 905328, "end_pos": 828059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070566.1", "url": "https://www.ensembl.org/id/ENSGALT00010070566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043257.1", "url": "https://www.ensembl.org/id/ENSGALP00010043257.1" } ] } }, { "isoform_ac": "A0A8V1AMJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0/entry#A0A8V1AMJ2-1", "sequence": { "sequence": "MNLHSSSVQQHDAYPLLFLMMCITPSELDHQQKPRKATPQPGEDTLNSHLPPGWQSYMSPQGRRYYVNTFTNETTWERPSSVPGTPKSPVTQQSPAVNGYHISGTPVHQLDSAHMNLRKASGDPQTPGSPAAPRRQSKESSLTINCVTFPHPDIMPEQQLLKPSEWSYCDYFWADKKDSQGNNTVSGFEILLQKQLKGKQMQKEMAEFVRERIKIEEEYAKNLSKLSQNSLAAQEEGTLGEAWAQLKKSLADEAEVHLKFSSKLQSEVEKPLLNFRENFKKDMKKCDHHIADLRKQLASRYAAVEKARKALTERQKDLEMKTQQLEVKLSNKTEEEIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVELVDQLLRKVDPAKDRELWVKEHKTGDIRPVDMEI", "length": 444, "header": "tr|A0A8V1AMJ2-1|A0A8V1AMJ2_CHICK Computationally mapped isoform of Growth arrest specific 7 OS=Gallus gallus OX=9031 GN=GAS7 PE=1 SV=1 CANONICAL=A0A8V1AKU0-1" }, "locus": { "chromosome": "18", "start_pos": 890819, "end_pos": 828059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070571.1", "url": "https://www.ensembl.org/id/ENSGALT00010070571.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043262.1", "url": "https://www.ensembl.org/id/ENSGALP00010043262.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "pmid": "" }, { "name": "clathrin coat assembly", "id": "GO:0048268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "pmid": "" }, { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 491, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AKU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 62, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AKU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU0" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 111, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 472, "end_pos": 474 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKU6-1", "uniprot_ac": "A0A8V1AKU6", "uniprot_id": "A0A8V1AKU6_CHICK", "mass": { "chemical_mass": 220243.0, "monoisotopic_mass": 220243.0 }, "refseq": { "ac": "XP_004946278", "name": "probable helicase with zinc finger domain isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946278" }, "gene_names": [ { "name": "HELZ", "type": "recommended", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "name": "HELZ", "type": "synonym", "evidence": [ { "id": "XP_004946278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946278" } ] } ], "protein_names": [ { "name": "ATP-dependent RNA helicase with zinc finger domain", "type": "recommended", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6/entry#names_and_taxonomy" } ] }, { "name": "probable helicase with zinc finger domain isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004946278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946278" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946278.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946278" } ] }, { "annotation": "ATP-dependent RNA helicase that promotes degradation of mRNAs via its association with the CCR4-NOT deadenylase complex, leading to deadenylation, decapping, and subsequent degradation of target mRNAs. Can repress translation independently of mRNA decay in a manner dependent on both the CCR4-NOT complex and the helicase DDX6. Involved in promoting cell proliferation, translation initiation, and ribosomal protein S6 (RPS6) phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ6#function" }, { "database": "UniProtKB", "id": "ARBA00094397", "url": "https://www.uniprot.org/uniprotkb/ARBA00094397#function" }, { "database": "UniProtKB", "id": "A0A8V1AKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6#function" }, { "database": "UniProtKB", "id": "A0A8V1AMJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMJ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HELZ", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6", "locus": { "chromosome": "18", "start_pos": 7850726, "end_pos": 7778748, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029204", "url": "https://www.ensembl.org/id/ENSGALG00010029204" } ] } } ], "crossref": [ { "id": "cd18077", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18077", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18808", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18808", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417427", "url": "https://www.ncbi.nlm.nih.gov/gene/417427", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIQ6", "url": "https://www.orthodb.org/?gene=A0A8V1AIQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKU6", "url": "https://www.orthodb.org/?gene=A0A8V1AKU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMJ4", "url": "https://www.orthodb.org/?gene=A0A8V1AMJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10887:SF365", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10887:SF365", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946278", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRRPEKSCEQACESLKQQDYEVAVKHCTEALLSLSQYPPAHLPEACQAEIDRIKIETLLYRIASFLQLKKYGQADEDCRHVLGEGLAKGDGSFRAVLCCMHLKGKLQIVSNVLSKSLMGESLNGMVTKDLTRLKTLLAETEAADKVPSGYHVEDLEEGSRDGWQFRPPPRGVTSSEEYTLCKRFLEQGICRYGAQCTSAHSQEELTEWQKRYASRLIRLKQQKENKQCSGSYMETLIEKWMNSLSPEKVLSESIEGVRVEHNPELSVTVTTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMVQNGIDHYIYKVSIAFNTEIFGTFRQTVVFDFGLEPVLMQRVMIDAASTEDLEYLMHARQQLLTTAKRWDSTSKTIVEFEPNETTELEKSLLTRYQIPLSADQLFTQSVLDKSLTKTNYQSRLHDLLYIEEIAQYKEVSKFNIKVQLQIVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPLTKEKSAQTQGTKEKVYEAAIEEKTKDYIFLRVSRECCEELNLRADCEMQVELQFQLNRLPLCEMHYALDRIKDNSILFPDVSMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLSIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQDTRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTHSTFQMPQKEDILKQRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALANKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENESLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRHQHSANTTKQQQSPPKGKVHHHNQNDHFPPDGIVQPNPSVLIGNPIRAYTPPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGGNMVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQAHGRGSPIPFGLGHHSPVSIGQQQQLQHPDKEQHEQSRNGKSEGTAGPEINKIRTPEKKPVESKQVDLDANSQTRSPESRSNGSYPNAKFHRKDNLNPRQLNLHLTPPHSQYAVPNRHFQHLSQIPRQPYPLQQQQNLLSQQQNHLPEQQNQIPPQQSQVVQQHNHLNQQPPQPSQLSPAYQAGPSQSFFNNPIPHRPHSPAVDAVISEQHPPPMLQEVSNPLRPIAQHNPVLPTHLNNFIEENPSGMPLGDTLDRMHGNVALETIRQQQQARLQQWNEHNAYLSQGTIPYQHHHHPHLPHLPQQPIGLHQQQQVRANWKLASNTEDETEATYSRFQDLLRELSHRDQSESRDLAEMPPPQSRLLQYRQVQPRSPPALPSPSCNSNHSGHFPNFTENNRDIEIPSNPAFQQHLPQIYNPPFSMPSEHITPSPLKYLQPDGSWTYANLQQNHLMGQGFHYGIPPLPHRSQQNPFIQIQNHQHAVGQEPFHPLTSRAVSASSLHSLEEYEPRGPGRPLYQRRISSSSVQACSEELSTPQDSLGQCKELQDHSNQSSFNYSSPELWVNSSSSAPYPNIPCNGANRAVPHRELLAPLKTVKPPEEHLKAENIQLSNSFNYSVLQHLGQFPPLMPNKQIMESNSTSQQNAGGSKPVMSYASALRAPPKPKPPPEQTKKNSDPLSLFQELSLGSSSGSNGFYSYFK", "length": 1941, "header": "tr|A0A8V1AKU6-1|A0A8V1AKU6_CHICK Isoform 1 of ATP-dependent RNA helicase with zinc finger domain OS=Gallus gallus OX=9031 GN=HELZ PE=3 SV=1 CANONICAL=A0A8V1AKU6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6/entry#A0A8V1AIQ6-1", "sequence": { "sequence": "MCKTRIGKLPEFRCDLSYSWKKYGQADEDCRHVLGEGLAKGDGSFRAVLCCMHLKGKLQIVSNVLSKSLMGESLNGMVTKDLTRLKTLLAETEAADKVPSGYHVEDLEEGSRDGWQFRPPPRGVTSSEEYTLCKRFLEQGICRYGAQCTSAHSQEELTEWQKRYASRLIRLKQQKENKQCSGSYMETLIEKWMNSLSPEKVLSESIEGVRVEHNPELSVTVTTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMVQNGIDHYIYKVSIAFNTEIFGTFRQTVVFDFGLEPVLMQRVMIDAASTEDLEYLMHARQQLLTTAKRWDSTSKTIVEFEPNETTELEKSLLTRYQIPLSADQLFTQSVLDKSLTKTNYQSRLHDLLYIEEIAQYKEVSKFNIKVQLQIVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPLTKEKSAQTQGTKEKVYEAAIEEKTKDYIFLRVSRECCEELNLRADCEMQVELQFQLNRLPLCEMHYALDRIKDNSILFPDVSMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLSIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQDTRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTHSTFQMPQKEDILKQRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALANKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENESLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRHQHSANTTKQQQSPPKGKVHHHNQNDHFPPDGIVQPNPSVLIGNPIRAYTPPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGGNMVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQAHGRGSPIPFGLGHHSPVSIGQQQQLQHPDKEQHEQSRNGKSEGTAGPEINKIRTPEKKPVESKQVDLDANSQTRSPESRSNGSYPNAKFHRKDNLNPRQLNLHLTPPHSQYAVPNRHFQHLSQIPRQPYPLQQQQNLLSQQQNHLPEQQNQIPPQQSQVVQQHNHLNQQPPQPSQLSPAYQAGPSQSFFNNPIPHRPHSPAVDAVISEQHPPPMLQEVSNPLRPIAQHNPVLPTHLNNFIEENPSGMPLGDTLDRMHGNVALETIRQQQQARLQQWNEHNAYLSQGTIPYQHHHHPHLPHLPQQPIGLHQQQQVRANWKLASNTEDETEATYSRFQDLLRELSHRDQSESRDLAEMPPPQSRLLQYRQVQPRSPPALPSPSCNSNHSGHFPNFTENNRDIEIPSNPAFQQHLPQIYNPPFSMPSEHITPSPLKYLQPDGSWTYANLQQNHLMGQGFHYGIPPLPHRSQQNPFIQIQNHQHAVGQEPFHPLTSRAVSASSLHSLEEYEPRGPGRPLYQRRISSSSVQACSEELSTPQDSLGQCKELQDHSNQSSFNYSSPELWVNSSSSAPYPNIPCNGANRAVPHRELLAPLKTVKPPEEHLKAENIQLSNSFNYSVLQHLGQFPPLMPNKQIMESNSTSQQNAGGSKPVMSYASALRAPPKPKPPPEQTKKNSDPLSLFQELSLGSSSGSNGFYSYFK", "length": 1891, "header": "tr|A0A8V1AIQ6-1|A0A8V1AKU6_CHICK Computationally mapped isoform of ATP-dependent RNA helicase with zinc finger domain OS=Gallus gallus OX=9031 GN=HELZ PE=3 SV=1 CANONICAL=A0A8V1AKU6-1" }, "locus": { "chromosome": "18", "start_pos": 7850386, "end_pos": 7794922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070574.1", "url": "https://www.ensembl.org/id/ENSGALT00010070574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043265.1", "url": "https://www.ensembl.org/id/ENSGALP00010043265.1" } ] } }, { "isoform_ac": "A0A8V1AKU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6/entry#A0A8V1AKU6-1", "sequence": { "sequence": "MADRRPEKSCEQACESLKQQDYEVAVKHCTEALLSLSQYPPAHLPEACQAEIDRIKIETLLYRIASFLQLKKYGQADEDCRHVLGEGLAKGDGSFRAVLCCMHLKGKLQIVSNVLSKSLMGESLNGMVTKDLTRLKTLLAETEAADKVPSGYHVEDLEEGSRDGWQFRPPPRGVTSSEEYTLCKRFLEQGICRYGAQCTSAHSQEELTEWQKRYASRLIRLKQQKENKQCSGSYMETLIEKWMNSLSPEKVLSESIEGVRVEHNPELSVTVTTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMVQNGIDHYIYKVSIAFNTEIFGTFRQTVVFDFGLEPVLMQRVMIDAASTEDLEYLMHARQQLLTTAKRWDSTSKTIVEFEPNETTELEKSLLTRYQIPLSADQLFTQSVLDKSLTKTNYQSRLHDLLYIEEIAQYKEVSKFNIKVQLQIVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPLTKEKSAQTQGTKEKVYEAAIEEKTKDYIFLRVSRECCEELNLRADCEMQVELQFQLNRLPLCEMHYALDRIKDNSILFPDVSMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLSIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQDTRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTHSTFQMPQKEDILKQRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALANKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENESLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRHQHSANTTKQQQSPPKGKVHHHNQNDHFPPDGIVQPNPSVLIGNPIRAYTPPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGGNMVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQAHGRGSPIPFGLGHHSPVSIGQQQQLQHPDKEQHEQSRNGKSEGTAGPEINKIRTPEKKPVESKQVDLDANSQTRSPESRSNGSYPNAKFHRKDNLNPRQLNLHLTPPHSQYAVPNRHFQHLSQIPRQPYPLQQQQNLLSQQQNHLPEQQNQIPPQQSQVVQQHNHLNQQPPQPSQLSPAYQAGPSQSFFNNPIPHRPHSPAVDAVISEQHPPPMLQEVSNPLRPIAQHNPVLPTHLNNFIEENPSGMPLGDTLDRMHGNVALETIRQQQQARLQQWNEHNAYLSQGTIPYQHHHHPHLPHLPQQPIGLHQQQQVRANWKLASNTEDETEATYSRFQDLLRELSHRDQSESRDLAEMPPPQSRLLQYRQVQPRSPPALPSPSCNSNHSGHFPNFTENNRDIEIPSNPAFQQHLPQIYNPPFSMPSEHITPSPLKYLQPDGSWTYANLQQNHLMGQGFHYGIPPLPHRSQQNPFIQIQNHQHAVGQEPFHPLTSRAVSASSLHSLEEYEPRGPGRPLYQRRISSSSVQACSEELSTPQDSLGQCKELQDHSNQSSFNYSSPELWVNSSSSAPYPNIPCNGANRAVPHRELLAPLKTVKPPEEHLKAENIQLSNSFNYSVLQHLGQFPPLMPNKQIMESNSTSQQNAGGSKPVMSYASALRAPPKPKPPPEQTKKNSDPLSLFQELSLGSSSGSNGFYSYFK", "length": 1941, "header": "tr|A0A8V1AKU6-1|A0A8V1AKU6_CHICK Isoform 1 of ATP-dependent RNA helicase with zinc finger domain OS=Gallus gallus OX=9031 GN=HELZ PE=3 SV=1 CANONICAL=A0A8V1AKU6-1" }, "locus": { "chromosome": "18", "start_pos": 7850386, "end_pos": 7793803, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070578.1", "url": "https://www.ensembl.org/id/ENSGALT00010070578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043269.1", "url": "https://www.ensembl.org/id/ENSGALP00010043269.1" } ] } }, { "isoform_ac": "A0A8V1AMJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6/entry#A0A8V1AMJ4-1", "sequence": { "sequence": "MTVLGEGLAKGDGSFRAVLCCMHLKGKLQIVSNVLSKSLMGESLNGMVTKDLTRLKTLLAETEAADKVPSGYHVEDLEEGSRDGWQFRPPPRGVTSSEEYTLCKRFLEQGICRYGAQCTSAHSQEELTEWQKRYASRLIRLKQQKENKQCSGSYMETLIEKWMNSLSPEKVLSESIEGVRVEHNPELSVTVTTKKSHQTWTFALTCKPARMLYRVALLYDAHRPHFSIIAISAGDSTTQVSQEVPENCQEWIGGKMVQNGIDHYIYKVSIAFNTEIFGTFRQTVVFDFGLEPVLMQRVMIDAASTEDLEYLMHARQQLLTTAKRWDSTSKTIVEFEPNETTELEKSLLTRYQIPLSADQLFTQSVLDKSLTKTNYQSRLHDLLYIEEIAQYKEVSKFNIKVQLQIVASFMLTGVSGGAKYAQNGQLFGRFKLTETLSEDTLAGRLVMTKVNAVYLLPLTKEKSAQTQGTKEKVYEAAIEEKTKDYIFLRVSRECCEELNLRADCEMQVELQFQLNRLPLCEMHYALDRIKDNSILFPDVSMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLSIQLPPVLIIGPYGTGKTFTLAQAVKHILQQQDTSRILICTHSNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSTHSTFQMPQKEDILKQRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALANKNTRIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKRKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENESLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRHQHSANTTKQQQSPPKGKVHHHNQNDHFPPDGIVQPNPSVLIGNPIRAYTPPPPPLGPHPNLGKSPSPVQRIDPHTGTSILYVPAVYGGNMVMSVPLPVPWTGYQGRFAVDPRIITHQAAMAYNMNLLQAHGRGSPIPFGLGHHSPVSIGQQQQLQHPDKEQHEQSRNGKSEGTAGPEINKIRTPEKKPVESKQVDLDANSQTRSPESRSNGSYPNAKFHRKDNLNPRQLNLHLTPPHSQYAVPNRHFQHLSQIPRQPYPLQQQQNLLSQQQNHLPEQQNQIPPQQSQVVQQHNHLNQQPPQPSQLSPAYQAGPSQSFFNNPIPHRPHSPAVDAVISEQHPPPMLQEVSNPLRPIAQHNPVLPTHLNNFIEENPSGMPLGDTLDRMHGNVALETIRQQQQARLQQWNEHNAYLSQGTIPYQHHHHPHLPHLPQQPIGLHQQQQVRANWKLASNTEDETEATYSRFQDLLRELSHRDQSESRDLAEMPPPQSRLLQYRQVQPRSPPALPSPSCNSNHSGHFPNFTENNRDIEIPSNPAFQQHLPQIYNPPFSMPSEHITPSPLKYLQPDGSWTYANLQQNHLMGQGFHYGIPPLPHRSQQNPFIQIQNHQHAVGQEPFHPLTSRAVSASSLHSLEEYEPRGPGRPLYQRRISSSSVQACSEELSTPQDSLGQCKELQDHSNQSSFNYSSPELWVNSSSSAPYPNIPCNGANRAVPHRELLAPLKTVKPPEEHLKAENIQLSNSFNYSVLQHLGQFPPLMPNKQIMESNSTSQQNAGGSKPVMSYASALRAPPKPKPPPEQTKKNSDPLSLFQELSLGSSSGSNGFYSYFK", "length": 1862, "header": "tr|A0A8V1AMJ4-1|A0A8V1AMJ4_CHICK Computationally mapped isoform of ATP-dependent RNA helicase with zinc finger domain OS=Gallus gallus OX=9031 GN=HELZ PE=3 SV=1 CANONICAL=A0A8V1AKU6-1" }, "locus": { "chromosome": "18", "start_pos": 7850386, "end_pos": 7778922, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070576.1", "url": "https://www.ensembl.org/id/ENSGALT00010070576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043267.1", "url": "https://www.ensembl.org/id/ENSGALP00010043267.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU6", "url": 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] } ] }, { "uniprot_ac": "A0A8V0XJV9", "gene_name": "SPATA5", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0XJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJV9" } ] } ] }, { "uniprot_ac": "A0A8V0XLC7", "gene_name": "MCM4", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XLC7", "database": 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} ] }, { "uniprot_ac": "A0A8V0ZTR5", "gene_name": "LOC423693", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZTR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZU49", "gene_name": "DNA2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU49" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0ZU49", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": 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"url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] } ] }, { "uniprot_ac": "F1P5C0", "gene_name": "DDX20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1P5C0", "database": "UniProtKB", "url": 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{ "name": "CUE domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015151674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151674" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151674.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151674" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CUEDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ8", "locus": { "chromosome": "19", "start_pos": 9237684, "end_pos": 9221490, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029511", "url": "https://www.ensembl.org/id/ENSGALG00010029511" } ] } } ], "crossref": [ { "id": "A0A8V1AIQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14366", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14366", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417665", "url": "https://www.ncbi.nlm.nih.gov/gene/417665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TDFKTMF", "url": "https://omabrowser.org/oma/group/TDFKTMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIQ8", "url": "https://www.orthodb.org/?gene=A0A8V1AIQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13467", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13467", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13467:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13467:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02845", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02845", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSLFRRSSSNGGSRGGSSAQELNNSRPARQVRRLEFNQAMEDFKTMFPNMDYDIIECVLRANNGAVDATIDQLLQMNLDGSGCEDSSDSEDSIPPEIIERTLEPDSSDEEPPPVYSPPAYESQVLGSPRAPPTPPPRADVPGPGRYRNWNPPLLGNLPEDFLRILPQQAAHTQGSPGCRQPVPRGQGSLEQERRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESKKSKLTSAAVSNDFCFSSVIPGDVATPGTSEAGSAVSDDALFRDKLKHMGKSTRKKLFELARAFSEKTKMRKSKRKHLLKHQVLGTAASTANLLDDVEGHSCDEDFQARRQQLREEEETLKEGQ", "length": 361, "header": "tr|A0A8V1AIQ8-1|A0A8V1AIQ8_CHICK Isoform 1 of CUE domain containing 1 OS=Gallus gallus OX=9031 GN=CUEDC1 PE=4 SV=1 CANONICAL=A0A8V1AIQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ8/entry#A0A8V1AIQ8-1", "sequence": { "sequence": "MTSLFRRSSSNGGSRGGSSAQELNNSRPARQVRRLEFNQAMEDFKTMFPNMDYDIIECVLRANNGAVDATIDQLLQMNLDGSGCEDSSDSEDSIPPEIIERTLEPDSSDEEPPPVYSPPAYESQVLGSPRAPPTPPPRADVPGPGRYRNWNPPLLGNLPEDFLRILPQQAAHTQGSPGCRQPVPRGQGSLEQERRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESKKSKLTSAAVSNDFCFSSVIPGDVATPGTSEAGSAVSDDALFRDKLKHMGKSTRKKLFELARAFSEKTKMRKSKRKHLLKHQVLGTAASTANLLDDVEGHSCDEDFQARRQQLREEEETLKEGQ", "length": 361, "header": "tr|A0A8V1AIQ8-1|A0A8V1AIQ8_CHICK Isoform 1 of CUE domain containing 1 OS=Gallus gallus OX=9031 GN=CUEDC1 PE=4 SV=1 CANONICAL=A0A8V1AIQ8-1" }, "locus": { "chromosome": "19", "start_pos": 9235175, "end_pos": 9230361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071335.1", "url": "https://www.ensembl.org/id/ENSGALT00010071335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044026.1", "url": "https://www.ensembl.org/id/ENSGALP00010044026.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 134, "start_aa": "Thr", "end_pos": 134, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr134", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 263, "start_aa": "Thr", "end_pos": 263, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr263", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MX67-1", "protein_name": "CUE domain containing 1", "gene_name": "CUEDC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSLFRRSSGGGGAAGARGAGAGAAASQELNNSRPARQVRRLEFNQAMDDFTTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEAGGGGVYEDSSDSEDSIPPEVLERTLEPDSSDEEPPPVYSPPAYHMHVLDRPYPLAPPTPPPRIDVLGSAPPSSQRRYRNWNPPLLGNLPEDFLRILPQQLDSIQATSRGSKLASTEGSLPPAAGPEPRDQESRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSTSSSVAVGNDFDFPSPVPGNSDASPAVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHAYDEDFRGRRQEVPTVEEALKEGQ", "length": 381 }, "evidence": [ { "id": "A0A8V1AIQ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RSB7-1", "protein_name": "CUE domain containing 1", "gene_name": "CUEDC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSLFRRSGGGGGGGGGGGGSAGARGAGGSAAASQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEAGGGSVYEDSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHMFDRPYPLAPPTPPPRIDVLGSVPPSSQRRYRNWNPPLLGNLPEDFLRILPQQLDSIQANSGSKPTSTEGGLTPAAGPGPRDQDSRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSTSSSVAVGNDFDFPSPAPGTSDANPAVSEDALFRDKLKHMGKSTQRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHTCDDEFRGRRQEAAKVEEALREGQ", "length": 387 }, "evidence": [ { "id": "A0A8V1AIQ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R3V6-1", "protein_name": "CUE domain-containing protein 1", "gene_name": "Cuedc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLFRRSSSGSGGGGATGARGAGTGAGDGSTAPQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEAGGGSAYEDSSDSEDSIPPEILERTLEPDSSEEEPPPVYSPPAYHMHVFDRPYLMAPPTPPPRIDVPGSGQPASQRRYRNWNPPLLGSLPDDFLRILPQQMDSIQGHPGGSKPMSGEGGPPPAPGPMACDQDSRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSKSNNAAVGNDGGFPSSVPGTSETNPTVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKKKHLPKLQSLGAAASTANLLDDVEGHAYEEDFRGRRQEVPKVEEALREGQ", "length": 388 }, "evidence": [ { "id": "A0A8V1AIQ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWM3-1", "protein_name": "CUE domain-containing protein 1", "gene_name": "CUEDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYEDSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPPTPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNAGGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ", "length": 386 }, "evidence": [ { "id": "A0A8V1AIQ8", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ8" }, { "id": "PS51140", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51140" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUE", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 79, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 134, 263 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIQ9-1", "uniprot_ac": "A0A8V1AIQ9", "uniprot_id": "A0A8V1AIQ9_CHICK", "mass": { "chemical_mass": 62591.0, "monoisotopic_mass": 62591.0 }, "refseq": { "ac": "NP_001026517", "name": "sorting nexin-27", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026517" }, "gene_names": [ { "name": "SNX27", "type": "recommended", "evidence": [ { "id": "A0A8V1AIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ] }, { "name": "SNX27", "type": "synonym", "evidence": [ { "id": "NP_001026517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026517" } ] } ], "protein_names": [ { "name": "Sorting nexin-27", "type": "recommended", "evidence": [ { "id": "A0A8V1AIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-27", "type": "synonym", "evidence": [ { "id": "NP_001026517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026517" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720623.1, HAEL01006608.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000353.1. On Sep 23, 2021 this sequence version replaced NP_001026517.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026517" } ] }, { "annotation": "Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosphatidylinositol-3-phosphate (PtdIns(3P)). May participate in establishment of natural killer cell polarity. Recruits CYTIP to early endosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9#function" }, { "database": "UniProtKB", "id": "ARBA00058700", "url": "https://www.uniprot.org/uniprotkb/ARBA00058700#function" }, { "database": "UniProtKB", "id": "A0A8V1A6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9", "locus": { "chromosome": "25", "start_pos": 2811480, "end_pos": 2795352, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027998", "url": "https://www.ensembl.org/id/ENSGALG00010027998" } ] } } ], "crossref": [ { "id": "A0A8V1AIQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06886", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06886", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13338", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13338", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23070", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425666", "url": "https://www.ncbi.nlm.nih.gov/gene/425666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425666", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425666", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNEFPHN", "url": "https://omabrowser.org/oma/group/PNEFPHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A6Q7", "url": "https://www.orthodb.org/?gene=A0A8V1A6Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIQ9", "url": "https://www.orthodb.org/?gene=A0A8V1AIQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12431:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12431:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026517", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026517", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A6Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADEEGEGPPRSAAAPQRNGGDEGAPGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLGGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISIPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDITTVTVRVKKNSTTDQVYQAVAAKVGMDSVTANYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEALLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLCEQRKMVMYLNMLRTCEGYNEIIFPHCSCDSRRKGHVITAISIKHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKEVEEEATDKDNQNCSTDTVCSKNIFQTVRSQQRDAAT", "length": 550, "header": "tr|A0A8V1AIQ9-1|A0A8V1AIQ9_CHICK Isoform 1 of Sorting nexin-27 OS=Gallus gallus OX=9031 GN=SNX27 PE=1 SV=1 CANONICAL=A0A8V1AIQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A6Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9/entry#A0A8V1A6Q7-1", "sequence": { "sequence": "MADEEGEGPPRSAAAPQRNGGDEGAPGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLGGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISIPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDITTVTVRVKKNSTTDQVYQAVAAKVGMDSVTANYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEALLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLCEQRKMVMYLNMLRTCEGYNEIIFPHCSCDSRRKGHVITAISIKHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYVSSPIPRRFEKPELLCVQVKWCHPGAHPGSSDL", "length": 527, "header": "tr|A0A8V1A6Q7-1|A0A8V1A6Q7_CHICK Computationally mapped isoform of Sorting nexin-27 OS=Gallus gallus OX=9031 GN=SNX27 PE=1 SV=1 CANONICAL=A0A8V1AIQ9-1" }, "locus": { "chromosome": "25", "start_pos": 2808791, "end_pos": 2795365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067864.1", "url": "https://www.ensembl.org/id/ENSGALT00010067864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041607.1", "url": "https://www.ensembl.org/id/ENSGALP00010041607.1" } ] } }, { "isoform_ac": "A0A8V1AIQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9/entry#A0A8V1AIQ9-1", "sequence": { "sequence": "MADEEGEGPPRSAAAPQRNGGDEGAPGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLGGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISIPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDITTVTVRVKKNSTTDQVYQAVAAKVGMDSVTANYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEALLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLCEQRKMVMYLNMLRTCEGYNEIIFPHCSCDSRRKGHVITAISIKHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKEVEEEATDKDNQNCSTDTVCSKNIFQTVRSQQRDAAT", "length": 550, "header": "tr|A0A8V1AIQ9-1|A0A8V1AIQ9_CHICK Isoform 1 of Sorting nexin-27 OS=Gallus gallus OX=9031 GN=SNX27 PE=1 SV=1 CANONICAL=A0A8V1AIQ9-1" }, "locus": { "chromosome": "25", "start_pos": 2811153, "end_pos": 2795365, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067865.1", "url": "https://www.ensembl.org/id/ENSGALT00010067865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041608.1", "url": "https://www.ensembl.org/id/ENSGALP00010041608.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425666", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425666", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480XS68-1", "protein_name": "Sorting nexin-27", "gene_name": "SNX27", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADEDGEGIHPAAPHRNGGGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTVRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKENIFQMARSQQRDVAT", "length": 541 }, "evidence": [ { "id": "A0A8V1AIQ9", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5PKA5-1", "protein_name": "Sorting nexin-27", "gene_name": "SNX27", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADEDGEGIHPAAPHRNGGGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKENIFQMARSQQRDVAT", "length": 541 }, "evidence": [ { "id": "A0A8V1AIQ9", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UHD6-1", "protein_name": "Sorting nexin-27", "gene_name": "Snx27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADEDGEGIHPSAPHRNGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEVLLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLHEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKENIFQMARSQQRDVAT", "length": 539 }, "evidence": [ { "id": "A0A8V1AIQ9", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K4V4-1", "protein_name": "Sorting nexin-27", "gene_name": "Snx27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADEDGEGIHPSTPHRNGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDGATVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEVLLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKENIFQMARSQQRDVAT", "length": 539 }, "evidence": [ { "id": "A0A8V1AIQ9", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96L92-1", "protein_name": "Sorting nexin-27", "gene_name": "SNX27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADEDGEGIHPSAPHRNGGGGGGGGSGLHCAGNGGGGGGGPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKAEEKSYQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRWDTDEEGMAFCFEYARGEKKPRWVKIFTPYFNYMHECFERVFCELKWRKENIFQMARSQQRDVAT", "length": 541 }, "evidence": [ { "id": "A0A8V1AIQ9", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W486-1", "protein_name": "3.4.24.-", "gene_name": "Snx27", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIVGENHPLPTPTPASAVVTASSGGGGGGAVVMGVGVGVTTANGPRVVTIYKTETGFGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLENGAAEKAGIKKGDRILEVNGVSVEGATHKQVVDLIKSGGDCLTLTVISVTQQEADRLEPQEDQSGYSYIDYSDKRSLPISIPDYGIVNRNGERYIVFNIHMAGRQLCSRRYREFANLHSLLRKEFSGFNFPKLPGKWPFQLSEQQLDTRRRGLEQYLEKVCAVRVIAESDAVQDFLTDTEDDISASPVDIKVMLPDHEVSTVSVKKSSNAQVVWEILVQRANLTAYTQQYFYLFEIVEYNFERKLQPHEIPHQLYVQNYSTASSTCLCVRRWLFSVAKELTLPDGEQAGRFIFYQAVDEVNRGNIRADGRLYELKALQDAKKAGDYLALARTLPGYGDVVFPHCSCDSRKEGHVVPAVGMKSFRLHACREDGSLEAQMVELTWDSITRSESDEESMSFCFQYNRPDKPARWVKVYTPYHAFLADCFDRIMEERKWEDSGD", "length": 531 }, "evidence": [ { "id": "A0A8V1AIQ9", "url": "https://omabrowser.org/oma/group/A0A8V1AIQ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "postsynaptic recycling endosome", "id": "GO:0098837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "immunological synapse", "id": "GO:0001772", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001772", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "postsynaptic early endosome", "id": "GO:0098842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "regulation of synapse maturation", "id": "GO:0090128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090128", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "regulation of postsynaptic membrane neurotransmitter receptor levels", "id": "GO:0099072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 124, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 257, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AIQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIQ9" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 261, "end_pos": 350, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 526, "end_pos": 528 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIR1-1", "uniprot_ac": "A0A8V1AIR1", "uniprot_id": "A0A8V1AIR1_CHICK", "mass": { "chemical_mass": 121034.0, "monoisotopic_mass": 121034.0 }, "refseq": { "ac": "NP_001376650", "name": "apical junction component 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376650" }, "gene_names": [ { "name": "AJM1", "type": "recommended", "evidence": [ { "id": "A0A8V1AIR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1" } ] }, { "name": "AJM1", "type": "synonym", "evidence": [ { "id": "NP_001376650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376650" } ] }, { "name": "C17H9ORF172", "type": "synonym", "evidence": [ { "id": "NP_001376650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376650" } ] } ], "protein_names": [ { "name": "Apical junction component 1 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1AIR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1/entry#names_and_taxonomy" } ] }, { "name": "apical junction component 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001376650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376650" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992453 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000308.1. On Sep 16, 2021 this sequence version replaced NP_001376650.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376650" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AJM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1", "locus": { "chromosome": "17", "start_pos": 1243811, "end_pos": 1251553, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028470", "url": "https://www.ensembl.org/id/ENSGALG00010028470" } ] } } ], "crossref": [ { "id": "A0A8V1AIR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "427779", "url": "https://www.ncbi.nlm.nih.gov/gene/427779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KEKTHDN", "url": "https://omabrowser.org/oma/group/KEKTHDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIR1", "url": "https://www.orthodb.org/?gene=A0A8V1AIR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21517:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21517:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26649", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26649", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27982", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27982", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376650", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376650", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRTDPPDILVSTVYQDIKVASAAPGDSIVCQPLARCDASMSSSLPRDPQPFNKRHCRSFDFLESLDEPLGAPPAMERPCPRPGTPEPTPGPPGRRAPPKPDPYGGRAPPPAREAPRGEPKRRARSKSAPRMKPSFTPVPIAVSASPPPARRGREALRVERGPPRAEPSPRRESHVPLRALANEVHPIKLQPQRSSVSRISPLCVGSNCFEEGPGAKVGASPHVKCRVDIKPDEAVLVHTARSLRAAQSRPELPQWPRAPRAARSLAVPGSRQVSVSRTPTPSDSYSGDPPLLPYPGEYFEADPRVLAYQTVPVPASREFREYPERGCMTFSAAGVPTKFFYAEEPVRCPSPAMPLRSSGYASYPYPVRQGPPQHFYVEDPAKAGVHTVPPRTLYVEEARGYPVQEAPSHAFYREEPRFYTPRSTPVKALYTEDARTYPALGSSARVFYAEDYGKYREREVLSRTCPPPRSTQPLHFGDWYCPERSALPYQSLQVSRFSPQPAGREAMLSSWHASYSTNPPRLGRDSQHYSKSWDNILAPAARREEALQRGRSYENLLVQEQHRALSPDERRQPVVINLSSSPKRYAALSLSESSILERVHSDSGRGPLGRSWYVTPEITITDNDIRANGTGRSERRSASWDVLDAGREQTPYAAPYAPQPVPKESGSARQRSLEQLDELITDLVIDYKPAPGHRAGDRDSLAEQLKKLLSSSAPGPPRRGEGRKVPPSVPESFRPTKEQPGPSSFGSAPRPQPSPPASGTFEKPLENCSPDLSAEEDDMMMCSNAKCRRTETMFNACLYFKSCHSCYTYYCSRHCRREDWDTHKESCVYGRVGSVCRHVLQFCRENAEVHKAFSRIAKVGYLSRGRGVLFLGFPNSGSAENFLQFGLESLLMSPTYLSLRELESYSDNLGEYARELRETGNQYDPDECFLLNVTVAVAQKVPERPSPKVQVPTVRKYAKVALASSSPEKKIPKKERDMETLILTPPPGTADIDKEGEEGRKAREVCFINIQRELRIRGVFLRHEFPAVYEQLCDFVESNKRFTPTTIYPIDKRTGKQFMCMIMAASEPRTLDWVASPNLLDDIM", "length": 1085, "header": "tr|A0A8V1AIR1-1|A0A8V1AIR1_CHICK Isoform 1 of Apical junction component 1 homolog OS=Gallus gallus OX=9031 GN=AJM1 PE=4 SV=1 CANONICAL=A0A8V1AIR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1/entry#A0A8V1AIR1-1", "sequence": { "sequence": "MTRTDPPDILVSTVYQDIKVASAAPGDSIVCQPLARCDASMSSSLPRDPQPFNKRHCRSFDFLESLDEPLGAPPAMERPCPRPGTPEPTPGPPGRRAPPKPDPYGGRAPPPAREAPRGEPKRRARSKSAPRMKPSFTPVPIAVSASPPPARRGREALRVERGPPRAEPSPRRESHVPLRALANEVHPIKLQPQRSSVSRISPLCVGSNCFEEGPGAKVGASPHVKCRVDIKPDEAVLVHTARSLRAAQSRPELPQWPRAPRAARSLAVPGSRQVSVSRTPTPSDSYSGDPPLLPYPGEYFEADPRVLAYQTVPVPASREFREYPERGCMTFSAAGVPTKFFYAEEPVRCPSPAMPLRSSGYASYPYPVRQGPPQHFYVEDPAKAGVHTVPPRTLYVEEARGYPVQEAPSHAFYREEPRFYTPRSTPVKALYTEDARTYPALGSSARVFYAEDYGKYREREVLSRTCPPPRSTQPLHFGDWYCPERSALPYQSLQVSRFSPQPAGREAMLSSWHASYSTNPPRLGRDSQHYSKSWDNILAPAARREEALQRGRSYENLLVQEQHRALSPDERRQPVVINLSSSPKRYAALSLSESSILERVHSDSGRGPLGRSWYVTPEITITDNDIRANGTGRSERRSASWDVLDAGREQTPYAAPYAPQPVPKESGSARQRSLEQLDELITDLVIDYKPAPGHRAGDRDSLAEQLKKLLSSSAPGPPRRGEGRKVPPSVPESFRPTKEQPGPSSFGSAPRPQPSPPASGTFEKPLENCSPDLSAEEDDMMMCSNAKCRRTETMFNACLYFKSCHSCYTYYCSRHCRREDWDTHKESCVYGRVGSVCRHVLQFCRENAEVHKAFSRIAKVGYLSRGRGVLFLGFPNSGSAENFLQFGLESLLMSPTYLSLRELESYSDNLGEYARELRETGNQYDPDECFLLNVTVAVAQKVPERPSPKVQVPTVRKYAKVALASSSPEKKIPKKERDMETLILTPPPGTADIDKEGEEGRKAREVCFINIQRELRIRGVFLRHEFPAVYEQLCDFVESNKRFTPTTIYPIDKRTGKQFMCMIMAASEPRTLDWVASPNLLDDIM", "length": 1085, "header": "tr|A0A8V1AIR1-1|A0A8V1AIR1_CHICK Isoform 1 of Apical junction component 1 homolog OS=Gallus gallus OX=9031 GN=AJM1 PE=4 SV=1 CANONICAL=A0A8V1AIR1-1" }, "locus": { "chromosome": "17", "start_pos": 1247199, "end_pos": 1243945, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068940.1", "url": "https://www.ensembl.org/id/ENSGALT00010068940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042382.1", "url": "https://www.ensembl.org/id/ENSGALP00010042382.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2AJA9-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "Ajm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAAPTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDSEPRRRTRSKSAPRASQGLATAPASPPVLQRRGREAQRAVRVEGSPRREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPEPPSGPVPHVRCRLDIKPDEAVLQHAARSSRSCAPRETTSWARTAPQFHGLTVPGPRHVALSRTPTPSDLYCTDPRTLYCDGPLPGPRDYLEHRSQPFTTPPGPTQFFYTEEPEGYAGSFTTSPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGMPFVPRYVPEEPRAHPGARTFYTEDFGRYRERDVLARTYPHPRSSPPWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGESLGRNWYVTPEITITDNDLRSVDRPTAKGWELPGGRPRQPVSTVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPAAEGLGRQLRRLLDSRAAGPGGATLLAPSRSPPASAGSTEEPTGSGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPSAAPPGAAARPAPRTPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRMRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 974 }, "evidence": [ { "id": "A0A8V1AIR1", "url": "https://omabrowser.org/oma/group/A0A8V1AIR1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C9J069-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "AJM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 976 }, "evidence": [ { "id": "A0A8V1AIR1", "url": "https://omabrowser.org/oma/group/A0A8V1AIR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZTF0-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "Ajm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAASTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDGEPRRRTRSKSAPRVPQSLTTAPASPPVLQRRGREAQRAVRVEGSPCREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPESSAGPVPHVRCRLDIKPDEAVLQHAARSSRSGAPRETSSWARTVPQFHGLTVPGPRHVALSRTPTPSDLYCTDPRPLYCDGPLPGPRDYLEHRTQPFTTPPGPTQFFYTEEPEGYAGSFTASPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGLPFVPRYVPEEPRVHPGARAFYTEDFGRYRERDALARTYPHPRSSPTWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLVTDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRTGECLGRNWYVTPEITITDNDLRSAERPTAKGWELPGGRPRQPVPVVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPTAEGLGRQLRRLLDSRPAGPGGATALAPSRSPPASAGSTEEPTGSGEAAEASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGAAPPGAAARPAPRSPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 974 }, "evidence": [ { "id": "A0A8V1AIR1", "url": "https://omabrowser.org/oma/group/A0A8V1AIR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B9Y2-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "AJM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVAAPGPVSRPPPCERPMARPAAPAPFNKRHCRSFDFLEGLDGVAMEARPEAPPPEPAAPRARSRDGETRRRARSKSAPRAPPNLAPAPASPPVLPRRGREAQRTARADASPRREPAYPALRALANELHPIKLQPQRGGPGRIAPLCAAANRCAPAEPPAGPAPHVRCRLDIKPDEAVLQHAARGSRPCGPPEPAPWPRAAPQLHGLTVPGPRHVALSRTPTPSDSYCTDPRALYCDGPLPGPRDYAERRSVPFTTPPGPTQFFYTEEPEGHPGGFMASPGPPFDGYYPRPFLPEEPPGPSPRRGSGYYAGEARTFPVQEPPSRSYYGEAPRAYGPPCGPRYAPEEPRARPAARAFYTEDFGRYRNREALTRTYPHPRGSPAWGDWGPRPYRTLQVAPPPDPGPLLASWHGGTGTSPPRLATDSRHYSRSWDNILASGPRREDPLGRGRSYENLLGHEAREPRGTSPEGRRPPVVVNLSTSPRRYAALSLSETSLSEKGRVGEGPGRNWYVTPEITITDNDLRAAERPAARSWEMPGSRPRQSQPAAPDGPASGRQRSLEQLDELITDLVIDSRSPAGQALEPTSDGLGRQLRRLLDSRPSGPGGPALAPRSPPASAGSAEEPAGQGQAADASPEPSADEDDLMTCSNARCGRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGATPPGAPARPVPAPRSPGPTVRKFAKVALAAGSPARPPPARGREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 975 }, "evidence": [ { "id": "A0A8V1AIR1", "url": "https://omabrowser.org/oma/group/A0A8V1AIR1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 933, "end_pos": 935, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR1" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 785, "end_pos": 828, "start_aa": "Asn", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 89, 281 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 578, "end_pos": 580 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 768, "end_pos": 770 }, { "start_pos": 933, "end_pos": 935 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIR8-1", "uniprot_ac": "A0A8V1AIR8", "uniprot_id": "A0A8V1AIR8_CHICK", "mass": { "chemical_mass": 17727.0, "monoisotopic_mass": 17727.0 }, "refseq": {}, "gene_names": [ { "name": "LOC123575613", "type": "recommended", "evidence": [ { "id": "A0A8V1AIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC123575613", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIR8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "123575613", "url": "https://www.ncbi.nlm.nih.gov/gene/123575613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "TVVLDNW", "url": "https://omabrowser.org/oma/group/TVVLDNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP07", "url": "https://www.orthodb.org/?gene=A0A8V1AP07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR41693", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41693", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41693:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41693:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "ARPGQSVCNQQHSRVRPGLAPGRLVKKGQQQLHGARAGGAEPSERPPRLQAGPGTAARAPRGCANLTLILDNWRFAITSQLRNLLLFHHHTVLPDYGRIRALSGALDELYEDFSALKEQLGRLSGRFVEVEAFVDQLSRSPGPRTAPRPGPRRRGLPQPALK", "length": 162, "header": "tr|A0A8V1AIR8-1|A0A8V1AIR8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC123575613 PE=4 SV=1 CANONICAL=A0A8V1AIR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8/entry#A0A8V1AIR8-1", "sequence": { "sequence": "ARPGQSVCNQQHSRVRPGLAPGRLVKKGQQQLHGARAGGAEPSERPPRLQAGPGTAARAPRGCANLTLILDNWRFAITSQLRNLLLFHHHTVLPDYGRIRALSGALDELYEDFSALKEQLGRLSGRFVEVEAFVDQLSRSPGPRTAPRPGPRRRGLPQPALK", "length": 162, "header": "tr|A0A8V1AIR8-1|A0A8V1AIR8_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC123575613 PE=4 SV=1 CANONICAL=A0A8V1AIR8-1" }, "locus": { "chromosome": "18", "start_pos": 9809730, "end_pos": 9808699, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071345.1", "url": "https://www.ensembl.org/id/ENSGALT00010071345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044036.1", "url": "https://www.ensembl.org/id/ENSGALP00010044036.1" } ] } }, { "isoform_ac": "A0A8V1AP07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIR8/entry#A0A8V1AP07-1", "sequence": { "sequence": "MARLLPLLLLAALGAAAKLKRQPAAWDERADAARAPRGCANLTLILDNWRFAITSQLRNLLLFHHHTVLPDYGRIRALSGALDELYEDFSALKEQLGRLSGRFVEVEAFVDQLSRSPGPRTAPRPGPRRRGLPQPALK", "length": 138, "header": "tr|A0A8V1AP07-1|A0A8V1AP07_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC123575613 PE=4 SV=1 CANONICAL=A0A8V1AIR8-1" }, "locus": { "chromosome": "18", "start_pos": 9809730, "end_pos": 9809133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071344.1", "url": "https://www.ensembl.org/id/ENSGALT00010071344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044035.1", "url": "https://www.ensembl.org/id/ENSGALP00010044035.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIS1-1", "uniprot_ac": "A0A8V1AIS1", "uniprot_id": "A0A8V1AIS1_CHICK", "mass": { "chemical_mass": 27443.0, "monoisotopic_mass": 27443.0 }, "refseq": { "ac": "XP_003642473", "name": "stromal cell-derived factor 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642473" }, "gene_names": [ { "name": "SDF2", "type": "recommended", "evidence": [ { "id": "A0A8V1AIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" } ] }, { "name": "SDF2", "type": "synonym", "evidence": [ { "id": "XP_003642473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642473" } ] } ], "protein_names": [ { "name": "Stromal cell derived factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1/entry#names_and_taxonomy" } ] }, { "name": "stromal cell-derived factor 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003642473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642473" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_003642473.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642473" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SDF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1", "locus": { "chromosome": "19", "start_pos": 6251258, "end_pos": 6253649, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029211", "url": "https://www.ensembl.org/id/ENSGALG00010029211" } ] } } ], "crossref": [ { "id": "A0A8V1AIS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23293", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23293", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427832", "url": "https://www.ncbi.nlm.nih.gov/gene/427832", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427832", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427832", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AIS1", "url": "https://www.orthodb.org/?gene=A0A8V1AIS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46809:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46809:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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CANONICAL=A0A8V1AIS1-1" }, "locus": { "chromosome": "19", "start_pos": 6253450, "end_pos": 6251895, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070594.1", "url": "https://www.ensembl.org/id/ENSGALT00010070594.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043285.1", "url": "https://www.ensembl.org/id/ENSGALP00010043285.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427832", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427832", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" } ], "pmid": "" }, { "name": "protein folding chaperone complex", "id": "GO:0101031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "misfolded protein binding", "id": "GO:0051787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein refolding", "id": "GO:0042026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS1" }, { "id": "PS50919", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50919" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIR", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 122, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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985, "header": "tr|A0A8V1AIS9-1|A0A8V1AIS9_CHICK Isoform 1 of Centrosomal protein 112 OS=Gallus gallus OX=9031 GN=CEP112 PE=4 SV=1 CANONICAL=A0A8V1AIS9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U8D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9/entry#A0A3Q2U8D0-1", "sequence": { "sequence": "MNGEEETWKELDAEFDRCVVDVKPHVLKLQHRSERQRCALWVKKLCEPSGAGTGIAGRRNRNSYAKLLLHMLKRGVLEDPFTHEPEPGMLKTLPSYMLIYFDEPNSTRIQSSSPDYLPDWVMGELGKGESRHEELWTLSSKEESPSATALTYEERLKYDGKPTLRSQSTSPLLRTDEDDLAAPLPDHHHKKTISLDDSDLDARLSSWNLGLENPRYLREKPMPVSLKTPKIGLGKGSSFQEDPALFRMHEKELDMKMKMMEGKFHEERLQLQQKHDSNVQKILDRKNDEIELLKSLHKSKQNEAEETIRKLEKKVQTLLRESQVIREAKEKQIVELKKMCEKSTESLNNEWEKKLHNAVAEMEKEKFSIRKKNTEDMRELLEDTNARLREMEEDYMEQIKSTNQTIKNLEARVQQLMVEAENSNLQRQKLSQEKTEAEQCYQAACSELQEMKARHKLFLEGKDRIVQEYEESIQQLQSKYDVDINVMKQEHALSAAKASDVIEELQHSVCLLKQQLQASEHQREQQLRDQDYKLQQDKLHLESVYEKQILGIQNDLDKERGDAQKKIHKLEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKQQMEKVEADLSRSKVLREKQSKEFSWQLEELKQRYEQQIVELKLEHEQEKTHLFQQHNAEKDCLVRDHEREIEKLEKQSRAAMAEHESRTQECRKRDGQVICDLESQIHKLNEELVQVKAQQKQQLMELSLQREEERQRAARDHKAAVSQLKAETERMVLDMKKVHAAETEKTLDKANCRLKQMEKEYSQKLAKSSQTLQDEVERSRSQARAAEKKLQRRELETHEQVTHIRQEYETKLKSLMPASLRQELEDTIVSLKSQVNILQKRASVQQEELNAYPTRR", "length": 901, "header": "tr|A0A3Q2U8D0-1|A0A3Q2U8D0_CHICK Computationally mapped isoform of Centrosomal protein 112 OS=Gallus gallus OX=9031 GN=CEP112 PE=4 SV=1 CANONICAL=A0A8V1AIS9-1" }, "locus": { "chromosome": "18", "start_pos": 8223776, "end_pos": 8085282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070611.1", "url": "https://www.ensembl.org/id/ENSGALT00010070611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043302.1", "url": "https://www.ensembl.org/id/ENSGALP00010043302.1" } ] } }, { "isoform_ac": "A0A8V1ABE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9/entry#A0A8V1ABE7-1", "sequence": { "sequence": "MNGEEETWKELDAEFDRCVVDVKPHVLKLQHRSERQRCALWVKKLCEPSGAGTGIAGRRNRNSYAKLLLHMLKRGVLEDPFTHEPEPGMLKTLPSYMLIYFDEPNSTRIQSSSPDYLPDWVMGELGKGESRHEELWTLSSKEESPSATALTYEERLKYDGKPTLRSQSTSPLLRTDEDDLAAPLPDHHHKKTISLDDSDLDARLSSWNLGLENPRYLREKPMPVSLKTPKIGLGKGSSFQEDPALFRMHEKELDMKMKMMEGKFHEERLQLQQKHDSNVQKILDRKNDEIELLKSLHKSKQNEAEETIRKLEKKVQTLLRESQVIREAKEKQIVELKKMCEKSTESLNNEWEKKLHNAVAEMEKEKFSIRKKNTEDMRELLEDTNARLREMEEDYMEQIKSTNQTIKNLEARVQQLMVEAENSNLQRQKLSQEKTEAEQCYQAACSELQEMKARHKLFLEGKDRIVQEYEESIQQLQSKYDVDINVMKQEHALSAAKASDVIEELQHSVCLLKQQLQASEHQREQQLRDQDYKLQQDKLHLESVYEKQILGIQNDLDKERGDAQKKIHKLEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKQQMEKVEADLSRSKVLREKQSKEFSWQLEELKQRYEQQIVELKLEHEQEKTHLFQQHNAEKDCLVRDHEREIEKLEKQSRAAMAEHESRTQECRKRDGQVICDLESQIHKLNEELVQVKAQQKQQLMELSLQREEERQRAARDHKAAVSQLKAETERMVLDMKKVHAAETEKTLDKANCRLKQMEKEYSQKLAKSSQIIAELKTTISSLTEENSRQQLAAEQRLQEVVQQFEDKKQQLITDNNRAIKTLQDEVERSRSQARAAEKKLQRRELETHEQVTHIRQEYETKLKSLMPASLRQELEDTIVSLKSQVNILQKRASVQQEELNAYPTRSCWSCWISLIAKWTAFNRFEDLALVN", "length": 976, "header": "tr|A0A8V1ABE7-1|A0A8V1ABE7_CHICK Computationally mapped isoform of Centrosomal protein 112 OS=Gallus gallus OX=9031 GN=CEP112 PE=4 SV=1 CANONICAL=A0A8V1AIS9-1" }, "locus": { "chromosome": "18", "start_pos": 8223855, "end_pos": 8085282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070610.1", "url": "https://www.ensembl.org/id/ENSGALT00010070610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043301.1", "url": "https://www.ensembl.org/id/ENSGALP00010043301.1" } ] } }, { "isoform_ac": "A0A8V1AIS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9/entry#A0A8V1AIS9-1", "sequence": { "sequence": "MVWPGMCRDGCRVVFNLVRFNAGDRTGCAVVSIKMNGEEETWKELDAEFDRCVVDVKPHVLKLQHRSERQRCALWVKKLCEPSGAGTGIAGRRNRNSYAKLLLHMLKRGVLEDPFTHEPEPGMLKTLPSYMLIYFDEPNSTRIQSSSPDYLPDWVMGELGKGESRHEELWTLSSKEESPSATALTYEERLKYDGKPTLRSQSTSPLLRTDEDDLAAPLPDHHHKKTISLDDSDLDARLSSWNLGLENPRYLREKPMPVSLKTPKIGLGKGSSFQEDPALFRMHEKELDMKMKMMEGKFHEERLQLQQKHDSNVQKILDRKNDEIELLKSLHKSKQNEAEETIRKLEKKVQTLLRESQVIREAKEKQIVELKKMCEKSTESLNNEWEKKLHNAVAEMEKEKFSIRKKNTEDMRELLEDTNARLREMEEDYMEQIKSTNQTIKNLEARVQQLMVEAENSNLQRQKLSQEKTEAEQCYQAACSELQEMKARHKLFLEGKDRIVQEYEESIQQLQSKYDVDINVMKQEHALSAAKASDVIEELQHSVCLLKQQLQASEHQREQQLRDQDYKLQQDKLHLESVYEKQILGIQNDLDKERGDAQKKIHKLEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKQQMEKVEADLSRSKVLREKQSKEFSWQLEELKQRYEQQIVELKLEHEQEKTHLFQQHNAEKDCLVRDHEREIEKLEKQSRAAMAEHESRTQECRKRDGQVICDLESQIHKLNEELVQVKAQQKQQLMELSLQREEERQRAARDHKAAVSQLKAETERMVLDMKKVHAAETEKTLDKANCRLKQMEKEYSQKLAKSSQIIAELKTTISSLTEENSRQQLAAEQRLQEVVQQFEDKKQQLITDNNRAIKTLQDEVERSRSQARAAEKKLQRRELETHEQVTHIRQEYETKLKSLMPASLRQELEDTIVSLKSQVNILQKRASVQQEELNAYPTRR", "length": 985, "header": "tr|A0A8V1AIS9-1|A0A8V1AIS9_CHICK Isoform 1 of Centrosomal protein 112 OS=Gallus gallus OX=9031 GN=CEP112 PE=4 SV=1 CANONICAL=A0A8V1AIS9-1" }, "locus": { "chromosome": "18", "start_pos": 8223776, "end_pos": 8085180, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070604.1", "url": "https://www.ensembl.org/id/ENSGALT00010070604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043295.1", "url": "https://www.ensembl.org/id/ENSGALP00010043295.1" } ] } }, { "isoform_ac": "A0A8V1AKW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9/entry#A0A8V1AKW7-1", "sequence": { "sequence": "MLYLIAMCGELIYFDEPNSTRIQSSSPDYLPDWVMGELGKGESRHEELWTLSSKEESPSATALTYEERLKYDGKPTLRSQSTSPLLRTDEDDLAAPLPDHHHKKTISLDDSDLDARLSSWNLGLENPRYLREKPMPVSLKTPKIGLGKGSSFQEDPALFRMHEKELDMKMKMMEGKFHEERLQLQQKHDSNVQKILDRKNDEIELLKSLHKSKQNEAEETIRKLEKKVQTLLRESQVIREAKEKQIVELKKMCEKSTESLNNEWEKKLHNAVAEMEKEKFSIRKKNTEDMRELLEDTNARLREMEEDYMEQIKSTNQTIKNLEARVQQLMVEAENSNLQRQKLSQEKTEAEQCYQAACSELQEMKARHKLFLEGKDRIVQEYEESIQQLQSKYDVDINVMKQEHALSAAKASDVIEELQHSVCLLKQQLQASEHQREQQLRDQDYKLQQDKLHLESVYEKQILGIQNDLDKERGDAQKKIHKLEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKQQMEKVEADLSRSKVLREKQSKEFSWQLEELKQRYEQQIVELKLEHEQEKTHLFQQHNAEKDCLVRDHEREIEKLEKQSRAAMAEHESRTQECRKRDGQVICDLESQIHKLNEELVQVKAQQKQQLMELSLQREEERQRAARDHKAAVSQLKAETERMVLDMKKVHAAETEKTLDKANCRLKQMEKEYSQKLAKSSQIIAELKTTISSLTEENSRQQLAAEQRLQEVVQQFEDKKQQLITDNNRAIKTLQDEVERSRSQARAAEKKLQRRELETHEQVTHIRQEYETKLKSLMPASLRQELEDTIVSLKSQVNILQKRASVQQEELNAYPTRR", "length": 864, "header": "tr|A0A8V1AKW7-1|A0A8V1AKW7_CHICK Computationally mapped isoform of Centrosomal protein 112 OS=Gallus gallus OX=9031 GN=CEP112 PE=4 SV=1 CANONICAL=A0A8V1AIS9-1" }, "locus": { "chromosome": "18", "start_pos": 8223776, "end_pos": 8086378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070603.1", "url": "https://www.ensembl.org/id/ENSGALT00010070603.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043294.1", "url": "https://www.ensembl.org/id/ENSGALP00010043294.1" } ] } }, { "isoform_ac": "A0A8V1AKW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9/entry#A0A8V1AKW9-1", "sequence": { "sequence": "MNGEEETWKELDAEFDRCVVDVKPHVLKLQHRSERQRCALWVKKLCEPSGAGTGIAGRRNRNSYAKLLLHMLKRGVLEDPFTHEPEPGMLKTLPSYMLIYFDEPNSTRIQSSSPDYLPDWVMGELGKGESRHEELWTLSSKEESPSATALTYEERLKYDGKPTLRSQSTSPLLRTDEDDLAAPLPDHHHKKTISLDDSDLDARLSSWNLGLENPRYLREKPMPVSLKTPKIGLGKGSSFQEDPALFRMHEKELDMKMKMMEGKFHEERLQLQQKHDSNVQKILDRKNDEIELLKSLHKSKQNEAEETIRKLEKKVQTLLRESQVIREAKEKQIVELKKMCEKSTESLNNEWEKKLHNAVAEMEKEKFSIRKKNTEDMRELLEDTNARLREMEEDYMEQIKSTNQTIKNLEARVQQLMVEAENSNLQRQKLSQEKTEAEQCYQAACSELQEMKARHKLFLEGKDRIVQEYEESIQQLQSKYDVDINVMKQEHALSAAKASDVIEELQHSVCLLKQQLQASEHQREQQLRDQDYKLQQDKLHLESVYEKQILGIQNDLDKERGDAQKKIHKLEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKQQMEKVEADLSRSKVLREKQSKEFSWQLEELKQRYEQQIVELKLEHEQEKTHLFQQHNAEKDCLVRDHEREIEKLEKQSRAAMAEHESRTQECRKRDGQVICDLESQIHKLNEELVQVKAQQKQQLMELSLQREEERQRAARDHKAAVSQLKAETERMVLDMKKVHAAETEKTLDKTLQDEVERSRSQARAAEKKLQRRELETHEQVTHIRQEYETKLKSLMPASLRQELEDTIVSLKSQVNILQKRASVQQEELNAYPTRR", "length": 880, "header": "tr|A0A8V1AKW9-1|A0A8V1AKW9_CHICK Computationally mapped isoform of Centrosomal protein 112 OS=Gallus gallus OX=9031 GN=CEP112 PE=4 SV=1 CANONICAL=A0A8V1AIS9-1" }, "locus": { "chromosome": "18", "start_pos": 8223776, "end_pos": 8085282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070608.1", "url": "https://www.ensembl.org/id/ENSGALT00010070608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043299.1", "url": "https://www.ensembl.org/id/ENSGALP00010043299.1" } ] } }, { "isoform_ac": "A0A8V1AML4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9/entry#A0A8V1AML4-1", "sequence": { "sequence": "MNGEEETWKELDAEFDRCVVDVKPHVLKLQHRSERQRCALWVKKLCEPSGAGTGIAGRRNRNSYAKLLLHMLKRGVLEDPFTHEPEPGMLKTLPSYMLIYFDEPNSTRIQSSSPDYLPDWVMGELGKGESRHEELWTLSSKEESPSATALTYEERLKYDGKPTLRSQSTSPLLRTDEDDLAAPLPDHHHKKTISLDDSDLDARLSSWNLGLENPRYLREKPMPVSLKTPKIGLGKGSSFQEDPALFRMHEKELDMKMKMMEGKFHEERLQLQQKHDSNVQKILDRKNDEIELLKSLHKSKQNEAEETIRKLEKKVQTLLRESQVIREAKEKQIVELKKMCEKSTESLNNEWEKKLHNAVAEMEKEKFSIRKKNTEDMRELLEDTNARLREMEEDYMEQIKSTNQTIKNLEARVQQLMVEAENSNLQRQKLSQEKTEAEQCYQAACSELQEMKARHKLFLEGKDRIVQEYEESIQQLQSKYDVDINVMKQEHALSAAKDQDYKLQQDKLHLESVYEKQILGIQNDLDKERGDAQKKIHKLEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKQQMEKVEADLSRSKVLREKQSKEFSWQLEELKQRYEQQIVELKLEHEQEKTHLFQQHNAEKDCLVRDHEREIEKLEKQSRAAMAEHESRTQECRKRDGQVICDLESQIHKLNEELVQVKAQQKQQLMELSLQREEERQRAARDHKAAVSQLKAETERMVLDMKKVHAAETEKTLDKANCRLKQMEKEYSQKLAKSSQIIAELKTTISSLTEENSRQQLAAEQRLQEVVQQFEDKKQQLITDNNRAIKTLQDEVERSRSQARAAEKKLQRRELETHEQVTHIRQEYETKLKSLMPASLRQELEDTIVSLKSQVNILQKRASVQQEELNAYPTRR", "length": 920, "header": "tr|A0A8V1AML4-1|A0A8V1AML4_CHICK Computationally mapped isoform of Centrosomal protein 112 OS=Gallus gallus OX=9031 GN=CEP112 PE=4 SV=1 CANONICAL=A0A8V1AIS9-1" }, "locus": { "chromosome": "18", "start_pos": 8223776, "end_pos": 8085282, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070606.1", "url": "https://www.ensembl.org/id/ENSGALT00010070606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043297.1", "url": "https://www.ensembl.org/id/ENSGALP00010043297.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIS9" }, { "id": "PF14846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4485", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 130, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 437, "end_pos": 439 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIT4-1", "uniprot_ac": "A0A8V1AIT4", "uniprot_id": "A0A8V1AIT4_CHICK", "mass": { "chemical_mass": 52488.0, "monoisotopic_mass": 52488.0 }, "refseq": { "ac": "XP_015148223", "name": "U3 small nucleolar RNA-interacting protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148223" }, "gene_names": [ { "name": "RRP9", "type": "recommended", "evidence": [ { "id": "A0A8V1AIT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4" } ] }, { "name": "RRP9", "type": "synonym", "evidence": [ { "id": "XP_015148223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148223" } ] } ], "protein_names": [ { "name": "U3 small nucleolar RNA-interacting protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AIT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4/entry#names_and_taxonomy" } ] }, { "name": "RRP9 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1AIT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4/entry#names_and_taxonomy" } ] }, { "name": "U3 small nucleolar RNA-interacting protein 2", "type": "synonym", "evidence": [ { "id": "XP_015148223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148223" } ] }, { "name": "U3 small nucleolar ribonucleoprotein-associated 55 kDa protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AIT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148223", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148223" } ] }, { "annotation": "Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4#function" }, { "database": "UniProtKB", "id": "ARBA00055322", "url": "https://www.uniprot.org/uniprotkb/ARBA00055322#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RRP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4", "locus": { "chromosome": "12", "start_pos": 180824, "end_pos": 176993, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028009", "url": "https://www.ensembl.org/id/ENSGALG00010028009" } ] } } ], "crossref": [ { "id": "A0A8V1AIT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415888", "url": "https://www.ncbi.nlm.nih.gov/gene/415888", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415888", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415888", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSLRIWK", "url": "https://omabrowser.org/oma/group/CSLRIWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIT4", "url": "https://www.orthodb.org/?gene=A0A8V1AIT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19865:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19865:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148223", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148223", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGRRARAVRRRRQPRVAGPSAEGKPGPAPHRRTRDEEVSSEEETESAAAGRRREEAASEEEVAETPQEKKLRLAKLYLEELRRHEEERAAEEEEEAAAFPGDLVGERLKEAVLEQQGRLRRPAAQDVCPPAPDAIRVLRGHQHSVTCLVVSPDDKFIFSAAKDGSVIKWEVESGKKLCVVPGGKKSTEGQPMGHTAHVLCIAISSDGKYLATGDRNKLILIWEAATCKRLYTFTGHRDAVSGLSFRKGTYQLYSASHDRSVKVWNVEENAYVETLFGHQDVITGMDSLSRECCVTSGGRDGTVRFWKIPEESQLIFYGHQGSIDCIQLINEEHMVSGADDGSVALWGLAKKKPLALVRQSHGTQGSAQDLQQPYWVSAVAALLNSDLVATGSHSGCVKLWKCGEGFQKLEPLCDIPLIGFVNSLKFSSAGDFMVAGIGQEHRLGRWWRVKEAKNSICIIPLKCRAGAPGPMAADST", "length": 479, "header": "tr|A0A8V1AIT4-1|A0A8V1AIT4_CHICK Isoform 1 of U3 small nucleolar RNA-interacting protein 2 OS=Gallus gallus OX=9031 GN=RRP9 PE=1 SV=1 CANONICAL=A0A8V1AIT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT4/entry#A0A8V1AIT4-1", "sequence": { "sequence": "MAAAGRRARAVRRRRQPRVAGPSAEGKPGPAPHRRTRDEEVSSEEETESAAAGRRREEAASEEEVAETPQEKKLRLAKLYLEELRRHEEERAAEEEEEAAAFPGDLVGERLKEAVLEQQGRLRRPAAQDVCPPAPDAIRVLRGHQHSVTCLVVSPDDKFIFSAAKDGSVIKWEVESGKKLCVVPGGKKSTEGQPMGHTAHVLCIAISSDGKYLATGDRNKLILIWEAATCKRLYTFTGHRDAVSGLSFRKGTYQLYSASHDRSVKVWNVEENAYVETLFGHQDVITGMDSLSRECCVTSGGRDGTVRFWKIPEESQLIFYGHQGSIDCIQLINEEHMVSGADDGSVALWGLAKKKPLALVRQSHGTQGSAQDLQQPYWVSAVAALLNSDLVATGSHSGCVKLWKCGEGFQKLEPLCDIPLIGFVNSLKFSSAGDFMVAGIGQEHRLGRWWRVKEAKNSICIIPLKCRAGAPGPMAADST", "length": 479, "header": "tr|A0A8V1AIT4-1|A0A8V1AIT4_CHICK Isoform 1 of U3 small nucleolar RNA-interacting protein 2 OS=Gallus gallus OX=9031 GN=RRP9 PE=1 SV=1 CANONICAL=A0A8V1AIT4-1" }, "locus": { "chromosome": "12", "start_pos": 180607, "end_pos": 177015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067890.1", "url": "https://www.ensembl.org/id/ENSGALT00010067890.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041633.1", "url": "https://www.ensembl.org/id/ENSGALP00010041633.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415888", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415888", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "B0BND5-1", "protein_name": "U3 small nucleolar RNA-interacting protein 2", "gene_name": "Rrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSMSTAVATRKRAKPAPGPGAAPVDGKRRRKVDSAASRGKSKGGGKMNEEISSDSESESLAPRKTEEEEEEELEETAQEKKLRLAKLYLEQLRQQEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKLVAKEIQAPAPTDIRVLRGHQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKLHVIPRAKKGTQGQPSGHSSHILCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRSVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLHGEPGLEQPFWISSVAALLNTDLVATGSHNACVRLWQCGEGFRQLDPLCDIPLVGFINSLKFSSGGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRVPVSPVAGS", "length": 478 }, "evidence": [ { "id": "A0A8V1AIT4", "url": "https://omabrowser.org/oma/group/A0A8V1AIT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H897-1", "protein_name": "U3 small nucleolar RNA-interacting protein 2", "gene_name": "Rrp9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSTAMATRKRAKPAPGSGADAVAGKRRRKVDSARDRGKSKGGGKMNEEISSDSETESLAPRKTEEEEEEELEETAQEKKLRLAKLYLEQLRQQEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKSVAKEIQAPAPTDIRVLRGHQLSITCLVVTPDDLAIFSAAKDCTIIKWSVESGRKLRVIPRAKKGTQGQPAGHSTHILCMAISSDGKYLASGDRSKLILIWDAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLHGEPGLEQPFWVSSVAALLNTDLVATGSHNACVRLWQCGEGFRQLDPLCDIPLVGFINSLKFSSAGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRLPAPPVAGS", "length": 475 }, "evidence": [ { "id": "A0A8V1AIT4", "url": "https://omabrowser.org/oma/group/A0A8V1AIT4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LQS7-1", "protein_name": "U3 small nucleolar RNA-interacting protein 2", "gene_name": "RRP9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSATVAARKRGKSASGAGAGAGAGKRRRKGDSSGDKGKSKGGGKMNEEISSDSENESIAPRKTEEEEEEELEETAQEKKLRLAKLYLEQLKQQEEEKAEAREFEEDQVAGKLKEDVLEQRGRLQKSVAKEIQAPAPADIRILRGHQLSITCLVITPDDLAIFSAAKDCTIIKWSVESGRKLHVIPRAKKGAEGQPPGHSSHILCMAISSDGKYLASGDRSKLILIWEAQSCRHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDSIQLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLRGEQGLEQPFWVSSVAALLNTDLIATGSHNNSVRLWQCGEGFRQLDLLCDIPLVGFINSLKFSSAGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLHRAPRPPAAGS", "length": 475 }, "evidence": [ { "id": "A0A8V1AIT4", "url": "https://omabrowser.org/oma/group/A0A8V1AIT4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43818-1", "protein_name": "U3 small nucleolar RNA-interacting protein 2", "gene_name": "RRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATAAARKRGKPASGAGAGAGAGKRRRKADSAGDRGKSKGGGKMNEEISSDSESESLAPRKPEEEEEEELEETAQEKKLRLAKLYLEQLRQQEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKLVAKEIQAPASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLRGEPGLEQPFWISSVAALLNTDLVATGSHSSCVRLWQCGEGFRQLDLLCDIPLVGFINSLKFSSSGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRVPVPPAAGS", "length": 475 }, "evidence": [ { "id": "A0A8V1AIT4", "url": "https://omabrowser.org/oma/group/A0A8V1AIT4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06506-1", "protein_name": "Ribosomal RNA-processing protein 9", "gene_name": "RRP9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDVTQQKKRKRSKGEVNPSKPTVDEEITDPSSNEDEQLEVSDEEDALESEEEFEGENPADKRRRLAKQYLENLKSEANDILTDNRNAEEKDLNNLKERTIDEYNNFDAGDLDKDIIASRLKEDVAEQQGRVFRYFGDKLLISEAKQSFTRVGENNLTCISCFQPVLNKYTFEESSNGDKNKGRLFAYTVSKDLQLTKYDITDFSKRPKKLKYAKGGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIVEDISALAMERCVTVGARDRTAMLWKIPDETRLTFRGGDEPQKLLRRWMKENAKEGEDGEVKYPDESEAPLFFCEGSIDVVSMVDDFHFITGSDNGNICLWSLAKKKPIFTERIAHGILPEPSFNDISGETDEELRKRQLQGKKLLQPFWITSLYAIPYSNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGKHGKEKFRILASIAKEHRLGRWIANVSGARNGIYSAVIDQTGF", "length": 573 }, "evidence": [ { "id": "A0A8V1AIT4", "url": "https://omabrowser.org/oma/group/A0A8V1AIT4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54BV0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSFFIKPGTAHTLSSNRAGAKNVVDTRINSRPSSNRGGRGGGMSSSRGGGGRGGRGGFMSSSRGGGRGGSMSSSRGGGRGGAMSSSRGGGKFRERESATNDTTNKYRDSKNNYKRKLSTEKDDYYDSDDNQDDEDNEKPSDEESDDNNNNIKNNFKNNIAVKKNINKYKNIDSDDQSDDDDDDDNNNGEIEEFHSGDEDRFNSENDSEEDKSSIKKRLKLSVVQEDETTDERRLRLANEYLEKIRKTKQDLDLNDAVKDDLDKSSGRYQYSYRQQVSNIKFIENSSNITILKGHSSPITCIVLSDDQSIAYSASRDIIIKWDLINKIKLNKIKGFIPSKKNRIELESLGKDGKEELKKKSYQGKILSMALSFDGKYLVTGGEEKLIKVWDTESMQVVETFKGHKDVISALTFRKGTYTLYSGSNDRTIKIWDLSQMAFVDTRYGHQSPITAMDSLSRERCISVSTDKTVRVWKIPEESQLIFRGHTHSVDCCVLVAEDKFLTGSQEGSIALWNVNKKNATFIKNNAHPVNSGGNSGTDSFSWISSVSAIPNSDMAASGSCDGSIRLWSIMGGDKLKEINQIPAIGFVNDLKFAHDCSFLLAAVSKEHKFGRWKKIGSAKNSLLLINLKEQVNPNDLLQQEEQVEIELNNNIENQDEDEEDEEEEEEEN", "length": 669 }, "evidence": [ { "id": "A0A8V1AIT4", "url": "https://omabrowser.org/oma/group/A0A8V1AIT4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q91WM3-1", "protein_name": "U3 small nucleolar RNA-interacting protein 2", "gene_name": "Rrp9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTAVATRKRAKPAPGPGAAPVAGKRRRKVDSAADRGKSKGGGKMNEEISSDSESESLAPRKTEEEEEEELEETAQEKKLRLAKLYLEQLRQQEEEKAEARAFEEDQVAGRLKEDVLEQRGRLQKSVAKEIQAPAPTDIRVLRGHQLSITCLVITPDDLAIFSAAKDCTIIKWSVETGRKLHVIPRAKKGAQGQPAGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRKGTHQLYSTSHDRSVKVWNAAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLHGEPGLEQPFWVSSVAALLNTDLVATGSHNARVRLWQCGEGFRQLDPLCDIPLVGFINSLKFSSAGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRLPVSPVAGS", "length": 475 }, "evidence": [ { "id": "A0A8V1AIT4", "url": "https://omabrowser.org/oma/group/A0A8V1AIT4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIT4", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR051427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GHTEEWQ", "url": "https://omabrowser.org/oma/group/GHTEEWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKM6", "url": "https://www.orthodb.org/?gene=A0A8V1AKM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23277:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23277:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418990", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-420597", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420597", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A8Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A8Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPTRPRAPTCATPPPPWQRCPRVVEGAPQCHPLLSAPTVPIVPIVPIVPIVPTVPIVPSVGGGFWRCQRPDPSRLCAPHNGSATCADPMSPPRHPAGRTDGQRDAVPAGAEGCDGGVVEVQRSVTAVLGQDAVLPCRYRAQEGEQVVQVTWLKRSASGRSTEVAVLDLRHGEHVQDAYVGRVRRRGDGALEDGGIVLRNAVQGDEGDYECHLITFPLGSFEGRVALRVLVPPLPILNPGPPLEEGQGRTLAASCTAEGNPVPTVRWETEVRGANATRQSQHDHSASVTSEFFVVPGRSMNGKSLTCVVAHPGLVQEKRIIHQLSVAYLSDASVLGHTEEWAEGMEGAALTCLGDGNPPPTYNWTRLDAPLPAGVRVKGDTLLFQRPLAAADAGDYVCRVANRVAAKEARANVSIKSRAAEDEVRRVDLVSASVVVVGVIAAVLLCVLVVVVVVMTLYHKRKTKRISEKYEEELTLTRENSIRRLHSSHSTDTRTQMEETLQLRTESRQGSLRGDSLRGDSLRGDSLRGDSLRGTSICSAMSEEAEGRSYSTLSTVREIETQTEVPVSPLLSPSLEGKEVKEEEEDGGDNPIKQAMTHFVQENGMLQARPSTNGIYINGRGHLV", "length": 625, "header": "tr|A0A8V1AIU8-1|A0A8V1AIU8_CHICK Isoform 1 of Nectin-4 OS=Gallus gallus OX=9031 GN=LOC101750739 PE=3 SV=1 CANONICAL=A0A8V1AIU8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A8Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8/entry#A0A8V1A8Y7-1", "sequence": { "sequence": "MHGALTSAHFVTLSVPSGCDGGVVEVQRSVTAVLGQDAVLPCRYRAQEGEQVVQVTWLKRSASGRSTEVAVLDLRHGEHVQDAYVGRVRRRGDGALEDGGIVLRNAVQGDEGDYECHLITFPLGSFEGRVALRVLVPPLPILNPGPPLEEGQGRTLAASCTAEGNPVPTVRWETEVRGANATRQSQHDHSASVTSEFFVVPGRSMNGKSLTCVVAHPGLVQEKRIIHQLSVAYLSDASVLGHTEEWAEGMEGAALTCLGDGNPPPTYNWTRLDAPLPAGVRVKGDTLLFQRPLAAADAGDYVCRVANRVAAKEARANVSIKSRAAEDEVRRVDLVSASVVVVGVIAAVLLCVLVVVVVVMTLYHKRKTKRISEKYEEELTLTRENSIRRLHSSHSTDTRTQMEETLQLRTESRQGSLRGDSLRGDSLRGDSLRGDSLRGTSICSAMSEEAEGRSYSTLSTVREIETQTEVPVSPLLSPSLEGKEVKEEEEDGGDNPIKQAMTHFVQENGMLQARPSTNGIYINGRGHLV", "length": 529, "header": "tr|A0A8V1A8Y7-1|A0A8V1A8Y7_CHICK Computationally mapped isoform of Nectin-4 OS=Gallus gallus OX=9031 GN=LOC101750739 PE=3 SV=1 CANONICAL=A0A8V1AIU8-1" }, "locus": { "chromosome": "25", "start_pos": 123850, "end_pos": 115144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068982.1", "url": "https://www.ensembl.org/id/ENSGALT00010068982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042424.1", "url": "https://www.ensembl.org/id/ENSGALP00010042424.1" } ] } }, { "isoform_ac": "A0A8V1AIU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8/entry#A0A8V1AIU8-1", "sequence": { "sequence": "MSPPTRPRAPTCATPPPPWQRCPRVVEGAPQCHPLLSAPTVPIVPIVPIVPIVPTVPIVPSVGGGFWRCQRPDPSRLCAPHNGSATCADPMSPPRHPAGRTDGQRDAVPAGAEGCDGGVVEVQRSVTAVLGQDAVLPCRYRAQEGEQVVQVTWLKRSASGRSTEVAVLDLRHGEHVQDAYVGRVRRRGDGALEDGGIVLRNAVQGDEGDYECHLITFPLGSFEGRVALRVLVPPLPILNPGPPLEEGQGRTLAASCTAEGNPVPTVRWETEVRGANATRQSQHDHSASVTSEFFVVPGRSMNGKSLTCVVAHPGLVQEKRIIHQLSVAYLSDASVLGHTEEWAEGMEGAALTCLGDGNPPPTYNWTRLDAPLPAGVRVKGDTLLFQRPLAAADAGDYVCRVANRVAAKEARANVSIKSRAAEDEVRRVDLVSASVVVVGVIAAVLLCVLVVVVVVMTLYHKRKTKRISEKYEEELTLTRENSIRRLHSSHSTDTRTQMEETLQLRTESRQGSLRGDSLRGDSLRGDSLRGDSLRGTSICSAMSEEAEGRSYSTLSTVREIETQTEVPVSPLLSPSLEGKEVKEEEEDGGDNPIKQAMTHFVQENGMLQARPSTNGIYINGRGHLV", "length": 625, "header": "tr|A0A8V1AIU8-1|A0A8V1AIU8_CHICK Isoform 1 of Nectin-4 OS=Gallus gallus OX=9031 GN=LOC101750739 PE=3 SV=1 CANONICAL=A0A8V1AIU8-1" }, "locus": { "chromosome": "25", "start_pos": 135523, "end_pos": 115144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068985.1", "url": "https://www.ensembl.org/id/ENSGALT00010068985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042427.1", "url": "https://www.ensembl.org/id/ENSGALP00010042427.1" } ] } }, { "isoform_ac": "A0A8V1AKM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8/entry#A0A8V1AKM6-1", "sequence": { "sequence": "MAPRGTRPGAAAFSLLLLLLLTGCDGGVVEVQRSVTAVLGQDAVLPCRYRAQEGEQVVQVTWLKRSASGRSTEVAVLDLRHGEHVQDAYVGRVRRRGDGALEDGGIVLRNAVQGDEGDYECHLITFPLGSFEGRVALRVLVPPLPILNPGPPLEEGQGRTLAASCTAEGNPVPTVRWETEVRGANATRQSQHDHSASVTSEFFVVPGRSMNGKSLTCVVAHPGLVQEKRIIHQLSVAYLSDASVLGHTEEWAEGMEGAALTCLGDGNPPPTYNWTRLDAPLPAGVRVKGDTLLFQRPLAAADAGDYVCRVANRVAAKEARANVSIKSRAAEDEVRRVDLVSASVVVVGVIAAVLLCVLVVVVVVMTLYHKRKTKRISEKYEEELTLTRENSIRRLHSSHSTDTRTQMEETLQLRTESRQGSLRGDSLRGDSLRGDSLRGDSLRGTSICSAMSEEAEGRSYSTLSTVREIETQTEVPVSPLLSPSLEGKEVKEEEEDGGDNPIKQAMTHFVQENGMLQARPSTNGIYINGRGHLV", "length": 534, "header": "tr|A0A8V1AKM6-1|A0A8V1AKM6_CHICK Computationally mapped isoform of Nectin-4 OS=Gallus gallus OX=9031 GN=LOC101750739 PE=3 SV=1 CANONICAL=A0A8V1AIU8-1" }, "locus": { "chromosome": "25", "start_pos": 130018, "end_pos": 115144, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068983.1", "url": "https://www.ensembl.org/id/ENSGALT00010068983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042425.1", "url": "https://www.ensembl.org/id/ENSGALP00010042425.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 14, "start_aa": "Thr", "end_pos": 14, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr14", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-418990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418990", "resource": "Reactome", "description": "Adherens junctions interactions" }, { "id": "R-GGA-420597", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-420597", "resource": "Reactome", "description": "Nectin/Necl trans heterodimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZET1-1", "protein_name": "Nectin-4", "gene_name": "Nectin4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLSLGAEMWGPEAWLLLLFLASFTGRYSAGELETSDLVTVVLGQDAKLPCFYRGDPDEQVGQVAWARVDPNEGTRELALLHSKYGLHVSPAYEDRVEQPPPPRDPLDGSILLRNAVQADEGEYECRVSTFPAGSFQARMRLRVLVPPLPSLNPGPPLEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTQSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHTLQVAFLAEASVRGLEDQNLWHVGREGATLKCLSEGQPPPKYNWTRLDGPLPSGVRVKGDTLGFPPLTTEHSGVYVCHVSNELSSRASQVTVEVLADPEDPGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRTEEEDDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV", "length": 509 }, "evidence": [ { "id": "A0A8V1AIU8", "url": "https://omabrowser.org/oma/group/A0A8V1AIU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" }, { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" }, { "name": "cell adhesion mediator activity", "id": "GO:0098631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098631", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" }, { "name": "heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0007157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" }, { "name": "negative regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIU8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 212, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 14, 55 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945753", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945753" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC189", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750428", "url": "https://www.ncbi.nlm.nih.gov/gene/101750428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032727", "url": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIV5-1", "uniprot_ac": "A0A8V1AIV5", "uniprot_id": "A0A8V1AIV5_CHICK", "mass": { "chemical_mass": 21785.0, "monoisotopic_mass": 21785.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121107750", "type": "recommended", "evidence": [ { "id": "A0A8V1AIV5", "database": "UniProtKB", "url": 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"database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIV5", "url": "https://www.orthodb.org/?gene=A0A8V1AIV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23010", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23010", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23010:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23010:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPQPGARSCSRGAAPCDPLPAERPVHLCIHTTTGARYEVAVPPDETVEGLKRRLSQRLKVPKERLALLHKDSRLSSGKLQDLGVVEGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSGCETKSSMGRGCRGPSRPHPVPSSPPLPAVPSGRGGSAEGGARGGRRHWVWGGPTLRPQPKQPRVVGGGCGGCGAVTQPRSSS", "length": 208, "header": "tr|A0A8V1AIV5-1|A0A8V1AIV5_CHICK Isoform 1 of Midnolin OS=Gallus gallus OX=9031 GN=LOC121107750 PE=4 SV=1 CANONICAL=A0A8V1AIV5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIV5/entry#A0A8V1AIV5-1", "sequence": { "sequence": "MEPQPGARSCSRGAAPCDPLPAERPVHLCIHTTTGARYEVAVPPDETVEGLKRRLSQRLKVPKERLALLHKDSRLSSGKLQDLGVVEGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSGCETKSSMGRGCRGPSRPHPVPSSPPLPAVPSGRGGSAEGGARGGRRHWVWGGPTLRPQPKQPRVVGGGCGGCGAVTQPRSSS", "length": 208, "header": "tr|A0A8V1AIV5-1|A0A8V1AIV5_CHICK Isoform 1 of Midnolin OS=Gallus gallus OX=9031 GN=LOC121107750 PE=4 SV=1 CANONICAL=A0A8V1AIV5-1" }, "locus": { "chromosome": "28", "start_pos": 3487205, "end_pos": 3485602, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067916.1", "url": "https://www.ensembl.org/id/ENSGALT00010067916.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041659.1", "url": "https://www.ensembl.org/id/ENSGALP00010041659.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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CANONICAL=A0A8V1AIW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIW5/entry#A0A8V1AIW5-1", "sequence": { "sequence": "MLRPQPLCVLLLLLHGGRAASPNNGTETPRAAEGNGTRTGAGLLPASGLPVLRRAVFVVSALSALAALYFVLRTFRSRPDGRRREPSAAFRWKKPQRKKYGLLSSSDERVEMASLDSDEDTVFETQNLRR", "length": 130, "header": "tr|A0A8V1AIW5-1|A0A8V1AIW5_CHICK Isoform 1 of Family with sequence similarity 174 member C OS=Gallus gallus OX=9031 GN=C19orf24 PE=3 SV=1 CANONICAL=A0A8V1AIW5-1" }, "locus": { "chromosome": "28", "start_pos": 3529503, "end_pos": 3528532, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067927.1", "url": "https://www.ensembl.org/id/ENSGALT00010067927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041670.1", "url": "https://www.ensembl.org/id/ENSGALP00010041670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], 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"evidence": [ { "id": "A0A8V1AIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ] }, { "name": "FCN2", "type": "synonym", "evidence": [ { "id": "XP_040505362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505362" } ] } ], "protein_names": [ { "name": "Ficolin 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6/entry#names_and_taxonomy" } ] }, { "name": "ficolin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040505362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505362" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505362" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FCN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6", "locus": {} } ], "crossref": [ { "id": "A0A8V1AIX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417298", 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}, { "id": "WNTGRGY", "url": "https://omabrowser.org/oma/group/WNTGRGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABS3", "url": "https://www.orthodb.org/?gene=A0A8V1ABS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEL7", "url": "https://www.orthodb.org/?gene=A0A8V1AEL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIX6", "url": "https://www.orthodb.org/?gene=A0A8V1AIX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V1AEL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSCRSRRKLCRHRQGTQAVGKRRGGAYMGFFGQCKSLRQLSANHNAWSTGKGSREWSTVLAMGRAAPILLALLSASATTCSTQDTCPEVKIVGLGEADRLAVLQGCPGIPGAAGPKGEPGLSGKKGEMGTKGPPGKAGPPGIKGAAGDPGLPGPKGEGRTRCGRQREIRGVCPTGAKGEPGFPEPLARNCQELLDKGKILSGWYTIHPQGCNATTVFCDMDTDGGGWIVFQRRLDGSVNFLRDWNSYKRGFGNQLTEFWLGNDNLHFLTSLGTCELRVDLRDFDNNYYFAKYASFRVLGESEKYKLVLGDFLGGNAGDSLSYHKDMSFSTADQDNDMSSFNCATAYKGAWWYNDCHYSNLNGMYWLGAHGSYADGINWKTGKEYHYSHKRTEMKFKPI", "length": 399, "header": "tr|A0A8V1AIX6-1|A0A8V1AIX6_CHICK Isoform 1 of Ficolin 2 OS=Gallus gallus OX=9031 GN=FCN2 PE=4 SV=1 CANONICAL=A0A8V1AIX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6/entry#A0A8V1ABS3-1", "sequence": { "sequence": "MGSCRSRRKLCRHRQGTQAVGKRRGGAYMGFFGQCKSLRQLSANHNAWSTGKGSREWSTVLAMGRAAPILLALLSASATTCSTQDTCPEVKIVGLGEADRLAVLQGCPGIPGAAGPKGEPGLSGKKGEMGTKGPPGKAGPPGIKGAAGDPGLPGPKARNCQELLDKGKILSGWYTIHPQGCNATTVFCDMDTDGGGWIVFQRRLDGSVNFLRDWNSYKRGFGNQLTEFWLGNDNLHFLTSLGTCELRVDLRDFDNNYYFAKYASFRVLGESEKYKLVLGDFLGGNAGDSLSYHKDMSFSTADQDNDMSSFNCATAYKGAWWYNDCHYSNLNGMYWLGAHGSYADGINWKTGKEYHYSHKRTEMKFKPI", "length": 368, "header": "tr|A0A8V1ABS3-1|A0A8V1ABS3_CHICK Computationally mapped isoform of Ficolin 2 OS=Gallus gallus OX=9031 GN=FCN2 PE=4 SV=1 CANONICAL=A0A8V1AIX6-1" }, "locus": { "chromosome": "17", "start_pos": 959773, "end_pos": 952482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067938.1", "url": "https://www.ensembl.org/id/ENSGALT00010067938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041681.1", "url": "https://www.ensembl.org/id/ENSGALP00010041681.1" } ] } }, { "isoform_ac": "A0A8V1AEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6/entry#A0A8V1AEL7-1", "sequence": { "sequence": "MGSCRSRRKLCRHRQGTQAVGKRRGGAYMGFFGQCKSLRQLSANHNAWSTGKGSREWSTVLAMGRAAPILLALLSASATTCSTQDTCPGEMGTKGPPGKAGPPGIKGAAGDPGLPGPKARNCQELLDKGKILSGWYTIHPQGCNATTVFCDMDTDGGGWIVFQRRLDGSVNFLRDWNSYKRGFGNQLTEFWLGNDNLHFLTSLGTCELRVDLRDFDNNYYFAKYASFRVLGESEKYKLVLGDFLGGNAGDSLSYHKDMSFSTADQDNDMSSFNCATAYKGAWWYNDCHYSNLNGMYWLGAHGSYADGINWKTGKEYHYSHKRTEMKFKPI", "length": 330, "header": "tr|A0A8V1AEL7-1|A0A8V1AEL7_CHICK Computationally mapped isoform of Ficolin 2 OS=Gallus gallus OX=9031 GN=FCN2 PE=4 SV=1 CANONICAL=A0A8V1AIX6-1" }, "locus": { "chromosome": "17", "start_pos": 959773, "end_pos": 952482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067935.1", "url": "https://www.ensembl.org/id/ENSGALT00010067935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041678.1", "url": "https://www.ensembl.org/id/ENSGALP00010041678.1" } ] } }, { "isoform_ac": "A0A8V1AIX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6/entry#A0A8V1AIX6-1", "sequence": { "sequence": "MGSCRSRRKLCRHRQGTQAVGKRRGGAYMGFFGQCKSLRQLSANHNAWSTGKGSREWSTVLAMGRAAPILLALLSASATTCSTQDTCPEVKIVGLGEADRLAVLQGCPGIPGAAGPKGEPGLSGKKGEMGTKGPPGKAGPPGIKGAAGDPGLPGPKGEGRTRCGRQREIRGVCPTGAKGEPGFPEPLARNCQELLDKGKILSGWYTIHPQGCNATTVFCDMDTDGGGWIVFQRRLDGSVNFLRDWNSYKRGFGNQLTEFWLGNDNLHFLTSLGTCELRVDLRDFDNNYYFAKYASFRVLGESEKYKLVLGDFLGGNAGDSLSYHKDMSFSTADQDNDMSSFNCATAYKGAWWYNDCHYSNLNGMYWLGAHGSYADGINWKTGKEYHYSHKRTEMKFKPI", "length": 399, "header": "tr|A0A8V1AIX6-1|A0A8V1AIX6_CHICK Isoform 1 of Ficolin 2 OS=Gallus gallus OX=9031 GN=FCN2 PE=4 SV=1 CANONICAL=A0A8V1AIX6-1" }, "locus": { "chromosome": "17", "start_pos": 959773, "end_pos": 952482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067937.1", "url": "https://www.ensembl.org/id/ENSGALT00010067937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041680.1", "url": "https://www.ensembl.org/id/ENSGALP00010041680.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 175, "start_aa": "Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-2855086", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2855086", "resource": "Reactome", "description": "Ficolins bind to repetitive carbohydrate structures on the target cell surface" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FNY0-1", "protein_name": "Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)", "gene_name": "FCN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTRGVAAAMRPLVLLVAFLCTAAPALDTCPEVKVVGLEGSDKLSILRGCPGLPGAAGPKGEAGADGPKGPHPAPPRLTEPPGLKVPGTDLPGAVRPGHCERSRLLPAVRGELGLESPPGLPALVSDWRGASAGAGIQGPRLLVPRVRPSTAFLRARPGVPGSGRFAHRRVLKLAGGQGPPGAPGEPGPPGPKGDRGEKGEPGPKGEAPALASTSPLPFPGPRTCKELLTRGHFLSGWHTIYLPDCQPLTVLCDMDTDGGGWTVFQRRSDGSVDFYRDWAAYKRGFGSQLGEFWLGNDHIHALTAQGTNELRVDLVDFEGNHQFAKYRSFQVADEAEKYMLVLGAFVEGNAGDSLTSHNNSLFTTKDQDNDQYASNCAVLYQGAWWYKSCHVSNLNGRYLGGSHGSFANGVNWSSGKGYNYSYKVSEMKFRAT", "length": 433 }, "evidence": [ { "id": "A0A8V1AIX6", "url": "https://omabrowser.org/oma/group/A0A8V1AIX6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q15485-1", "protein_name": "Ficolin-2", "gene_name": "FCN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA", "length": 313 }, "evidence": [ { "id": "A0A8V1AIX6", "url": "https://omabrowser.org/oma/group/A0A8V1AIX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" }, { "name": "antigen binding", "id": "GO:0003823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" }, { "name": "carbohydrate derivative binding", "id": "GO:0097367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097367", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "complement activation, lectin pathway", "id": "GO:0001867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX6" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 399, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 175 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AIZ2-1", "uniprot_ac": "A0A8V1AIZ2", "uniprot_id": "A0A8V1AIZ2_CHICK", "mass": { "chemical_mass": 134996.0, "monoisotopic_mass": 134996.0 }, "refseq": { "ac": "XP_015155600", "name": "cartilage intermediate layer protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155600" }, "gene_names": [ { "name": "CILP2", "type": "recommended", "evidence": [ { "id": "A0A8V1AIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2" } ] }, { "name": "CILP2", "type": "synonym", "evidence": [ { "id": "XP_015155600", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155600" } ] } ], "protein_names": [ { "name": "Cartilage intermediate layer protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AIZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2/entry#names_and_taxonomy" } ] }, { "name": "cartilage intermediate layer protein 2", "type": "synonym", "evidence": [ { "id": "XP_015155600", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155600" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155600.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155600" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CILP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2", "locus": { "chromosome": "28", "start_pos": 3885779, "end_pos": 3893021, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028510", "url": "https://www.ensembl.org/id/ENSGALG00010028510" } ] } } ], "crossref": [ { "id": "A0A8V1AIZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AIZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "430666", "url": "https://www.ncbi.nlm.nih.gov/gene/430666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430666", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430666", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RLEKPYM", "url": "https://omabrowser.org/oma/group/RLEKPYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIZ2", "url": "https://www.orthodb.org/?gene=A0A8V1AIZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23591", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23591", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23599", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23599", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23730", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23730", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155600", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERLLLPALLALAAFCCSGAAESLENDSEPGKSDAPGKPWKVPSPEELDLNTAGGGAEWTSWFNIDHPGGDGDYESLDAIRFYYRGRVCARPVAIQARTTEWELPQDVGEVVHFSPKKGFRCVNKEQPHGKTCSNYHIRFLCPLEHIFWSHWSSWSPCSRSACGSSGTQSRRRRCVNAQAVSALKELKCRGKAVERRPCSTGPCPEPMWTEWGAWGPCSRSCGSTGTRVRRRSCQNARKLLCAGHPSEVQQCPPTPCPACPEHTLQGAVVSATGAALPGARVYLEGRPPTLLARSDTRGAFRVPGLCVSIGANVSAHRDGFAPGLTSVVSNGSGALVAHIVLQKLEKPYMVLHPTPKVRVAGQEVTFCCKASGTPVPKKYYWYQNGTLLDRTAHRYSSRLVLRALTPEQAGSYHCKASTEAGAIRSAPAQLTVLAQGQQSCKAAPEPSLVELPAECHRDAGASRYYDVGHCPSTPCAGSPADGQRCGAGARRCCGVRRMEMREIRCGGSVLPIKVVAKCGCGPCAQPRVLVQGRVTAADTGEPLRFGQIFLGKKKIGFTGFQGSFTIEVPPDTQRLVARFVDRQQRLVDAVKVLPFDRRGGAVYQEVKMMRKKEAVELDAGQTNAIPLGEASGREPIAELVIPAGAFLRPSGEVFGGTVKASVTFLDPRDMATARAASSDLSFANADGEIVPLRTYGMFAVDFRDGESGTALQTGPVEVRMDAGQIGMAEHLRKMKLWSLNPETGLWEEEGVLRPTEERRGRREERTFLVGNMEIRERRLFNLDVPEDRRCFVKVRAYSNEKFNPYEQLEGVVISLINLEPQPGFPANPRAWGRFDSVVTGPNGACLPAFCDARRPDAYTAYITATLGGEELEAVPSSPKLNPNAVGVSQPYLNKLGYRRLDHDDPDIKKTAFQVNVAKPDPNNIDETNGPIYPYRSLRECEEAPVSANHFRFYRVEVDKYEYNVVPFKESDLTSWTGDYLSWWPNPQEFRACFIKVRIEGPQEYMVRSRNEGGSHPRTVGQLYGLRDARSVRDAMREGSSGACLEFKCSGMLYDQSLVDRTLVSVIPQGSCRRTAVNGLLRDYLARHPPVADANNTAAFTMLAPVDPLGHNYGIYTVTDQNPRLAKEIAIGRCFDGTSDGFSREMKSDAGTAVTFTCQERPAGRESFFQRLLTSPAEALDEIRREMGAGELRRAPPEVLDFASGVRALSPAPPPRTPGSRRRMGRVRAQQ", "length": 1231, "header": "tr|A0A8V1AIZ2-1|A0A8V1AIZ2_CHICK Isoform 1 of Cartilage intermediate layer protein 2 OS=Gallus gallus OX=9031 GN=CILP2 PE=4 SV=1 CANONICAL=A0A8V1AIZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2/entry#A0A8V1AIZ2-1", "sequence": { "sequence": "MERLLLPALLALAAFCCSGAAESLENDSEPGKSDAPGKPWKVPSPEELDLNTAGGGAEWTSWFNIDHPGGDGDYESLDAIRFYYRGRVCARPVAIQARTTEWELPQDVGEVVHFSPKKGFRCVNKEQPHGKTCSNYHIRFLCPLEHIFWSHWSSWSPCSRSACGSSGTQSRRRRCVNAQAVSALKELKCRGKAVERRPCSTGPCPEPMWTEWGAWGPCSRSCGSTGTRVRRRSCQNARKLLCAGHPSEVQQCPPTPCPACPEHTLQGAVVSATGAALPGARVYLEGRPPTLLARSDTRGAFRVPGLCVSIGANVSAHRDGFAPGLTSVVSNGSGALVAHIVLQKLEKPYMVLHPTPKVRVAGQEVTFCCKASGTPVPKKYYWYQNGTLLDRTAHRYSSRLVLRALTPEQAGSYHCKASTEAGAIRSAPAQLTVLAQGQQSCKAAPEPSLVELPAECHRDAGASRYYDVGHCPSTPCAGSPADGQRCGAGARRCCGVRRMEMREIRCGGSVLPIKVVAKCGCGPCAQPRVLVQGRVTAADTGEPLRFGQIFLGKKKIGFTGFQGSFTIEVPPDTQRLVARFVDRQQRLVDAVKVLPFDRRGGAVYQEVKMMRKKEAVELDAGQTNAIPLGEASGREPIAELVIPAGAFLRPSGEVFGGTVKASVTFLDPRDMATARAASSDLSFANADGEIVPLRTYGMFAVDFRDGESGTALQTGPVEVRMDAGQIGMAEHLRKMKLWSLNPETGLWEEEGVLRPTEERRGRREERTFLVGNMEIRERRLFNLDVPEDRRCFVKVRAYSNEKFNPYEQLEGVVISLINLEPQPGFPANPRAWGRFDSVVTGPNGACLPAFCDARRPDAYTAYITATLGGEELEAVPSSPKLNPNAVGVSQPYLNKLGYRRLDHDDPDIKKTAFQVNVAKPDPNNIDETNGPIYPYRSLRECEEAPVSANHFRFYRVEVDKYEYNVVPFKESDLTSWTGDYLSWWPNPQEFRACFIKVRIEGPQEYMVRSRNEGGSHPRTVGQLYGLRDARSVRDAMREGSSGACLEFKCSGMLYDQSLVDRTLVSVIPQGSCRRTAVNGLLRDYLARHPPVADANNTAAFTMLAPVDPLGHNYGIYTVTDQNPRLAKEIAIGRCFDGTSDGFSREMKSDAGTAVTFTCQERPAGRESFFQRLLTSPAEALDEIRREMGAGELRRAPPEVLDFASGVRALSPAPPPRTPGSRRRMGRVRAQQ", "length": 1231, "header": "tr|A0A8V1AIZ2-1|A0A8V1AIZ2_CHICK Isoform 1 of Cartilage intermediate layer protein 2 OS=Gallus gallus OX=9031 GN=CILP2 PE=4 SV=1 CANONICAL=A0A8V1AIZ2-1" }, "locus": { "chromosome": "28", "start_pos": 3892822, "end_pos": 3886559, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069040.1", "url": "https://www.ensembl.org/id/ENSGALT00010069040.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042482.1", "url": "https://www.ensembl.org/id/ENSGALP00010042482.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 255, "start_aa": "Thr", "end_pos": 255, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr255", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:430666", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430666", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z7H8-1", "protein_name": "Cartilage intermediate layer protein 2", "gene_name": "Cilp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPLPLLYLCLAALHLAGARDATPTEEHTSTARGLQGRPPDTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAMGERVHANPERGFWCLNREQPRGRRCSNYHVRFRCPLEAAWGAWGAWGLCSKSCGLGRRLRRRSCQSSSGDTCPGSPQEAQKCVRSRCPGCSSDTCGCPNHILLGSVVTPSGRPLSGARVSLRTRPGTIATSGTHGTFQVPGVCAGSKASVSAQMNGFSAGTAQAHANSSNTATVTIILEELGKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRQQGSGPHLELQGLHQAQAGEYHCKAWNEAGTVRSRAALLTILAPGQQACDPRPQEHLIKLPDDCGQPGGGPTYLDVGLCADTRCPGPVGSGPRCGDAGSRCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRRGLVRGRVVAADSGEPLRFARILLGRAPIGFTSYQGDFTIEVPPATERLVVTFVDPSGDFVDSVRVLPFDPRGAGVYHEIRALRKAAAVLLDAERGGEIPLGSTEEAPALGELVLPPGTFHHPDGRPYTGPVEARVTFVDPRDLASASAASSDLRFLDSAGELAPLRTYGMFAVDLRAPGSTEQLHVARADVHVDADHVRMPGHAEALALWSLDPETGLWEEEGSEQGSGGFRRETAAARVRREERAFLVGALTMRERRLFNLDVPERRRCFVKVRAYGTDRFAPAEQVQGVVVTLLNLEPAPGFTANPRAWGRFDSAVTGPNGACVPAFCDAEKPDAYTAFVTAALGGEELEAAPSRPRATAAVVGVAQPYLERLGYQRTDHDDPALKRTGFRLNLARPRAGHESEAHGPVYPWRRLRDCEDAPVTDSHFRFSRVEADKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQGPQEYMVRSHNAGGTHEATRGRLYGLRDTRSVRHPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSCRRVAVNTLLQDYLARHPPLAAADDPAAFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPARPSLFQRLLENPSSALGDIRREMGQATRYSRVNQTQAGDTGPFGPGQ", "length": 1162 }, "evidence": [ { "id": "A0A8V1AIZ2", "url": "https://omabrowser.org/oma/group/A0A8V1AIZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZE05-1", "protein_name": "Cartilage intermediate layer protein 2", "gene_name": "Cilp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSPLPLLYLCIAAAHLAGARDATPTEEHTATVRGLQGRPPDPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPAAIGERVHANPERGFWCLNREQPRGRRCSNYHVRFRCPLDPPYLPPCSAEAAWGAWGAWGLCSKSCGPGRRLRRRSCQSSSGDTCPGSPQEAQKCVRSRCPAPPKSSLCPCCSHVPLGCSSDTCGCPNHILLGSVVTPSGRPLSGARVSLRTRPGTVATSDTHGTFRVPGVCAGSKANVSARMNGFSTGTAQAHANTSNSAVVTIVLEELGKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRQQGSGPHLELQGLREEQAGEYHCKAWNEAGTVRSRAAHLTVLAPGQPACDPRPQEHLIKLPDDCGQPGGGPTYLDVGLCADTRCPGPVGSGPRCGDAGSRCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRRGLVRGRVVAADSGEPLRFARILLGLAPIGFTSYQGDFTIEVPPATERLVVTFVDSSGEFVDSIRVLPFDPRGAGVYHEIRVLRKAAAVLLDAEQGGEIPLGGTEEAPALGELVFPPRTFHHPDGRPYSGPVEARVTFVDPRDLASAAAASSDLRYLDSSGELAPLRTYGMFAVDLHAPGSTEQLHVARADVRVDADHVRMPGHADALALWSLDPETGLWEEEGAEQGGGGFRREKEAVRVRREERTFLVGALTVRERRLFNLDVPERRRCFVKVRAYGTDRFAPSEQVQGVVVTLLNLEPAPGFTANPRAWGRFDSAVTGPNGACVPAFCDAERPDAYTAFVTASLGGEELEAAPSRPRATAATVGVAEPYLERLGYQRTDHDDPALKRTGFRLNLARPRTGHESEAHGPVYPWRRLRDCEDAPVTDSHFRFSRVEADKYEYDVVPFHEGAPASWTGDLLAWWPNPQEFRACFLKVRLQGPQEYMVRSHNAGGTHEDTRGHLYGLRDTRSVRNPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSCRRVAVNTLLQDYLARHPPLAPADDPATFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPARPSLFQRLLENPASALGDIRREMGQAARDSRVTQTQAGDTGPFGSGQ", "length": 1188 }, "evidence": [ { "id": "A0A8V1AIZ2", "url": "https://omabrowser.org/oma/group/A0A8V1AIZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BKL4-1", "protein_name": "Cartilage intermediate layer protein 2", "gene_name": "CILP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSLPTLLCLCVAAAHLAGARGTPDAEEPTVTAWGLEGSSLRPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSDVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEATWGSWGPWGPCSGSCGPGRRLRRRRCSSPAGDACPGRPSEAQKCVRPRCPGCGPSTCGCPDHILLGSVVTPSGRPLPGARVSLRDWPGTIATSDAHGTFRMPGVCASSQANVSAQMDGFSAGMTQAQANSSMSSVATVVLNKLEKPYLVKHPESQVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRTHRYGAHLELHGLRPDQAGTYHCKAWNDAGAVRSGAARLTVLAPGQPACDPRPREHLIKLPDDCGQPGRGPTYLDVGLCPDTLCPSPAGSSPRCGDAGSRCCSVRRLESRKIHCSGYTLPVKVVAECGCQKCLPLRGLIRGRVVAADSREPLRFARILLGREPIGFTSYQGDFTLEVAPSTQRLVMTFVDPSGQFVDTVRVLPFDPRGAGVYHEVKAMRKKAPIILDARQSNTISLGEMGEEAPLGELIIPPGAFRRADGQPYTGAVEAQVTFVDPRNLTSAAAAPSDLLFVDGDGELAPLRTYGMFSVDLRAAGSAEQLQTGLVAVRVAADQIRMPGHMEALKLWSLNPDTGLWEEESGFQRERPASQRARREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADQPDAYTAVVTATLGGEELEPAPSRPRPLPAAVGVAQPYLDRLDYRRTDHDDPALKRSGFRINLAKPRPGEPTEANGPVYPWRSLRECQEAPVTASHFRFARVEADKYEYNVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNLGGSHPRTQGQLYGLRDSRSVRDPQRPSSSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLQDYLTRHPPLAPTDDLASFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPTAGRPSLFQRLLESPSAALGDIRREMGESARVQARASSPLRTRRGRAQQ", "length": 1157 }, "evidence": [ { "id": "A0A8V1AIZ2", "url": "https://omabrowser.org/oma/group/A0A8V1AIZ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q5N7-1", "protein_name": "Cartilage intermediate layer protein 1", "gene_name": "cilp2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWDFTVVTLVLSTVFVVSLAQGPIWDSSRLRRLNQTDRNRKLAYNTLVEPQTTGVTEWTSWFNIDHPGGNGDYERLEAIRFYYRERVCSRPVAMEARTTDWVAAADTGEVVHSSLEKGFWCINKEQPFGRSCSNYHVRFQCPPVHSYWTDWSEWTPCSATACNDVGIQVRQRKCMSTQPLPLLLSPVCVGPHIERRECSTPPCQAMWSQWGSWGACSVTCGKGRRTRRRTCHRSSTKIQCTGRPIEVQKCGNPCPVKCKRVCPGGRPDKSCSYCICDGQALHGEVFSITGVPVMNATVALASQAKIIRAHTDAKGQFKMDGLCISPQTQIVIRKDKFAPATLPVSNNSTDELWVRAILQSSEKPYIEKHPEDKVRYEGQRATLCCRATGSPKPDKYYWYHNGTLLNRTIFKYDEDLILRDLKPEQSGQYHCKATSLTGSIKSTSAVLTVFTKGTPACKSTPETHLIKLPLDCKQPGTDSKFYNAGRCPHNKCPGALDFDMRCRDGTGFCCGVKEMDAKEINCGRYTLPIKVVSECGCQTCVEPKVLVRGRVVATDNDEPLRFGHIYIGKERIGTTGYQGGFTIQVSPETQRLVVNFVDPSQKFIDTIKVFIFDKRGGAVYHDVKVMRKQEPIDINAAESNTIYLGEMKDEDPIGQLVIPPNSFHKNTGEVYEGTVKASVTFLDPRNITMAAAAPGDLNFVDDEGDMLPLRTYGMFSVDFRDGENQEVLGAGAVQVLLDTEHVKMQEHIPAMKLWSLNPDTGIWEEESNFQPTQSTIAGTGRNKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAYMSDKFLPNEQLEGVVINLINLEPKPGYSSNPRAWGRFDSVITGPNGACLPAFCDAQRADAYTAYVTAIMGGEELEAAPSMPKMNPNIIGVSQPYLGKLDYQRSDHEDSALKKTAFRINLAKPNPNNFDETNGPIYPFQSLIACENAPVDANHFRFFRVEKDKYEYNVVPFQESDLTSWTGDYLSWWPNPQEFRACFIKVKIHGATEIMVRSRNLGGTHPQTRGQLYGIRDIRSTRDLHHPNTSAACLEFKCSGMLFDQGSVDRSLISVIPQANCRRIGINSLLQEYLIKHPPVLQNNESHAFNMLAPVDPLGHNYGIYTVTDQNPRVAKEIAIGRCFDGTSDGFSREMKSDSGVALTFSCPKRTVNRESLFQRLQTNPGLTLTQMAREMRESQGLQVRRGSTQMVAYPFGQQGRSQNRRATNTNRRRPASRTQPRQ", "length": 1255 }, "evidence": [ { "id": "A0A8V1AIZ2", "url": "https://omabrowser.org/oma/group/A0A8V1AIZ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IUL8-1", "protein_name": "Cartilage intermediate layer protein 2", "gene_name": "CILP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLLPLLCLCVVAAHLAGARDATPTEEPMATALGLERRSVYTGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPSAVGERVHLNPTRGFWCLNREQPRGRRCSNYHVRFRCPLEASWGAWGPWGPCSGSCGPGRRLRRRHCPSPAGDACPGRPLEAQKCVRPRCPGCSLDTCECPDHILLGSVVTPSGQPLLGARVSLRDQPGTVATSDAHGTFRVPGVCADSRANIRAQMDGFSAGEAQAQANGSISVVTIILDKLEKPYLVKHPESRVREAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRAHGYGAHLELRGLRPDQAGIYHCKAWNEAGAVRSGTARLTVLAPGQPACDPRPREYLIKLPEDCGQPGSGPAYLDVGLCPDTRCPSLAGSSPRCGDASSRCCSVRRLERREIHCPGYVLPVKVVAECGCQKCLPPRGLVRGRVVAADSGEPLRFARILLGQEPIGFTAYQGDFTIEVPPSTQRLVVTFVDPSGEFMDAVRVLPFDPRGAGVYHEVKAMRKKAPVILHTSQSNTIPLGELEDEAPLGELVLPSGAFRRADGKPYSGPVEARVTFVDPRDLTSAASAPSDLRFVDSDGELAPLRTYGMFSVDLRAPGSAEQLQVGPVAVRVAASQIHMPGHVEALKLWSLNPETGLWEEESGFRREGSSGPRVRREERVFLVGNVEIRERRLFNLDVPERRRCFVKVRAYANDKFTPSEQVEGVVVTLVNLEPAPGFSANPRAWGRFDSAVTGPNGACLPAFCDADRPDAYTALVTATLGGEELEPAPSLPRPLPATVGVTQPYLDRLGYRRTDHDDPAFKRNGFRINLAKPRPGDPAEANGPVYPWRSLRECQGAPVTASHFRFARVEADKYEYNVVPFREGTPASWTGDLLAWWPNPQEFRACFLKVKIQGPQEYMVRSHNAGGSHPRTRGQLYGLRDARSVRDPERPGTSAACVEFKCSGMLFDQRQVDRTLVTIMPQGSCRRVAVNGLLRDYLTRHPPPVPAEDPAAFSMLAPLDPLGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPPAGRPSLFQRLLESPATALGDIRREMSEAAQAQARASGPLRTRRGRVRQ", "length": 1156 }, "evidence": [ { "id": "A0A8V1AIZ2", "url": "https://omabrowser.org/oma/group/A0A8V1AIZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AIZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNLFGRKRRSRVTEQDKAVLQLKQQRDKLRQYQKRISLGLERERELARQLLKEGKKEKAMLLLKKKRYQEQLLDKTDNQISNLERMVQDIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERIIGETQDAVEYQRQIDEILAGSLTEEDEDAILEELNAITQEQLELPDVPSEPLPEEPPEHPSRTGQNQSWWQHLNSRFWGSPHNFHPGQFAIPACAGNKQCLGSIPAVLGRLWSRIPCAGWGTSADRLLLLYQDYFLVLSFFVTSILNSLSCAVLGLNNNSKTSKAKHFSLGLISAVNLPLLCPIPSQLSPWAASV", "length": 321, "header": "tr|A0A8V1AJ03-1|A0A8V1AJ03_CHICK Isoform 1 of Charged multivesicular body protein 6 OS=Gallus gallus OX=9031 GN=CHMP6 PE=3 SV=1 CANONICAL=A0A8V1AJ03-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03/entry#A0A8V1ADL7-1", "sequence": { "sequence": "MNQFTAIYNGNGELINNIKYYDGFMGQRVGAISCLAFHPHWQLKQQRDKLRQYQKRISLGLERERELARQLLKEGKKEKAMLLLKKKRYQEQLLDKTDNQISNLERMVQDIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERIIGETQDAVEYQRQIDEILAGSLTEEDEDAILEELNAITQEQLELPDVPSEPLPEEPPEATPVKNRPKPELVAAS", "length": 220, "header": "tr|A0A8V1ADL7-1|A0A8V1ADL7_CHICK Computationally mapped isoform of Charged multivesicular body protein 6 OS=Gallus gallus OX=9031 GN=CHMP6 PE=3 SV=1 CANONICAL=A0A8V1AJ03-1" }, "locus": { "chromosome": "18", "start_pos": 9980779, "end_pos": 9973184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071430.1", "url": "https://www.ensembl.org/id/ENSGALT00010071430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044120.1", "url": "https://www.ensembl.org/id/ENSGALP00010044120.1" } ] } }, { "isoform_ac": "A0A8V1AJ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03/entry#A0A8V1AJ03-1", "sequence": { "sequence": "MGNLFGRKRRSRVTEQDKAVLQLKQQRDKLRQYQKRISLGLERERELARQLLKEGKKEKAMLLLKKKRYQEQLLDKTDNQISNLERMVQDIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERIIGETQDAVEYQRQIDEILAGSLTEEDEDAILEELNAITQEQLELPDVPSEPLPEEPPEHPSRTGQNQSWWQHLNSRFWGSPHNFHPGQFAIPACAGNKQCLGSIPAVLGRLWSRIPCAGWGTSADRLLLLYQDYFLVLSFFVTSILNSLSCAVLGLNNNSKTSKAKHFSLGLISAVNLPLLCPIPSQLSPWAASV", "length": 321, "header": "tr|A0A8V1AJ03-1|A0A8V1AJ03_CHICK Isoform 1 of Charged multivesicular body protein 6 OS=Gallus gallus OX=9031 GN=CHMP6 PE=3 SV=1 CANONICAL=A0A8V1AJ03-1" }, "locus": { "chromosome": "18", "start_pos": 9976754, "end_pos": 9972817, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071427.1", "url": "https://www.ensembl.org/id/ENSGALT00010071427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044117.1", "url": "https://www.ensembl.org/id/ENSGALP00010044117.1" } ] } }, { "isoform_ac": "A0A8V1AKS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03/entry#A0A8V1AKS2-1", "sequence": { "sequence": "MGNLFGRKRRSRVTEQDKAVLQLKQQRDKLRQYQKRISLGLERERELARQLLKEGKKEKAMLLLKKKRYQEQLLDKTDNQISNLERMVQDIEFTQIEMKVIEGLKIGNECLNKMHQVMSIEEVERIIGETQDAVEYQRQIDEILAGSLTEEDEDAILEELNAITQEQLELPDVPSEPLPEEPPASCFHSKCF", "length": 192, "header": "tr|A0A8V1AKS2-1|A0A8V1AKS2_CHICK Computationally mapped isoform of Charged multivesicular body protein 6 OS=Gallus gallus OX=9031 GN=CHMP6 PE=3 SV=1 CANONICAL=A0A8V1AJ03-1" }, "locus": { "chromosome": "18", "start_pos": 9976754, "end_pos": 9970868, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071429.1", "url": "https://www.ensembl.org/id/ENSGALT00010071429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044119.1", "url": "https://www.ensembl.org/id/ENSGALP00010044119.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" }, { "id": "R-GGA-5620971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620971", "resource": "Reactome", "description": "Pyroptosis" }, { "id": "R-GGA-917729", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-917729", "resource": "Reactome", "description": "Endosomal Sorting Complex Required For Transport (ESCRT)" }, { "id": "R-GGA-9668328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9668328", "resource": "Reactome", "description": "Sealing of the nuclear envelope (NE) by ESCRT-III" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "ESCRT III complex", "id": "GO:0000815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" }, { "name": "multivesicular body", "id": "GO:0005771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005771", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "nuclear membrane reassembly", "id": "GO:0031468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" }, { "name": "vesicle budding from membrane", "id": "GO:0006900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" }, { "name": "late endosome to vacuole transport via multivesicular body sorting pathway", "id": "GO:0032511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" }, { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJ21-1", "uniprot_ac": "A0A8V1AJ21", "uniprot_id": "A0A8V1AJ21_CHICK", "mass": { "chemical_mass": 35357.0, "monoisotopic_mass": 35357.0 }, "refseq": { "ac": "XP_004945818", "name": "leucine-rich repeat-containing protein 26", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945818" }, "gene_names": [ { "name": "LRRC26", "type": "recommended", "evidence": [ { "id": "A0A8V1AJ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" } ] }, { "name": "LRRC26", "type": "synonym", "evidence": [ { "id": "XP_004945818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945818" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 26", "type": "synonym", "evidence": [ { "id": "A0A8V1AJ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 26", "type": "synonym", "evidence": [ { "id": "XP_004945818", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945818" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945818.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945818", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945818" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJ21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ21", "database": "AlphaFoldDB", "categories": [] }, { "id": "101749800", "url": "https://www.ncbi.nlm.nih.gov/gene/101749800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749800", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749800", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAAFSHC", "url": 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"Protein" ] }, { "id": "A0A8V1AJ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLPGAGHIQLLTAPKGARQGRVAGQGEGCWASCLGATLMPGTGEPSPHGWVTMGRWRGPSILLAVLLLLRPLPAPACPHTCHCWAGDVDCRQRALHEVPPLLPTNASTLWLGYNLIAVLGARAFPSLPVLLRLSLPHNRLEKIHRQALLGLRELQELDLSDNYLSVLNPETFLPLTSLSMLNLGYNRLEELEAGVLHALPQLQAIFLNGNPWMCSCSILPLWHWLGHNREKVPERSSLQCVFPESLNTYPITAFGNDSFQQCQKVPLSAQHYAAFLLIGPFSFLASIFCCTLIGFIVVIYQHLRKEPQTWRRPLSSGGH", "length": 320, "header": "tr|A0A8V1AJ21-1|A0A8V1AJ21_CHICK Isoform 1 of Leucine rich repeat containing 26 OS=Gallus gallus OX=9031 GN=LRRC26 PE=4 SV=1 CANONICAL=A0A8V1AJ21-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21/entry#A0A8V1AJ21-1", "sequence": { "sequence": "MQLPGAGHIQLLTAPKGARQGRVAGQGEGCWASCLGATLMPGTGEPSPHGWVTMGRWRGPSILLAVLLLLRPLPAPACPHTCHCWAGDVDCRQRALHEVPPLLPTNASTLWLGYNLIAVLGARAFPSLPVLLRLSLPHNRLEKIHRQALLGLRELQELDLSDNYLSVLNPETFLPLTSLSMLNLGYNRLEELEAGVLHALPQLQAIFLNGNPWMCSCSILPLWHWLGHNREKVPERSSLQCVFPESLNTYPITAFGNDSFQQCQKVPLSAQHYAAFLLIGPFSFLASIFCCTLIGFIVVIYQHLRKEPQTWRRPLSSGGH", "length": 320, "header": "tr|A0A8V1AJ21-1|A0A8V1AJ21_CHICK Isoform 1 of Leucine rich repeat containing 26 OS=Gallus gallus OX=9031 GN=LRRC26 PE=4 SV=1 CANONICAL=A0A8V1AJ21-1" }, "locus": { "chromosome": "17", "start_pos": 1675990, "end_pos": 1674299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069075.1", "url": "https://www.ensembl.org/id/ENSGALT00010069075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042517.1", "url": "https://www.ensembl.org/id/ENSGALP00010042517.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101749800", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749800", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IG36-1", "protein_name": "Leucine-rich repeat-containing protein 26", "gene_name": "Lrrc26", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRGSFFSRLLPQLSLLLLLLLLLLSLRRVWAQEHVGTAPSRSPVAPECPEACSCSLGGKVNCSALELPAVPVGLNWRISSLLLDHNRVSTLPPGAFAGAGGLLYLDLRENRLRSVHARAFWGLGVLQWLDLSANQLETLSPGTFAPLRALRFLSLAGNRLTLLEPSILGALPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLRGNPWACSCALRPLCTWLRKHPRPASETENLLCVSPRRQTLSLLTAFPDAAFRHCTQPLAARDLAVVYSLGPVSFLASLAICLALGSVLTACSARRRRRRTTVRPLLRRQVDPSGPASLEDAGRPAAAATQA", "length": 335 }, "evidence": [ { "id": "A0A8V1AJ21", "url": "https://omabrowser.org/oma/group/A0A8V1AJ21/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2I0M4-1", "protein_name": "Leucine-rich repeat-containing protein 26", "gene_name": "LRRC26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGPSWSRPRPLLLLLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGRLTLSPLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARRRRLRTAALRPPRPPDPNPDPDPHGCASPADPGSPAAAAQA", "length": 334 }, "evidence": [ { "id": "A0A8V1AJ21", "url": "https://omabrowser.org/oma/group/A0A8V1AJ21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P7C4-1", "protein_name": "Leucine-rich repeat-containing protein 26", "gene_name": "Lrrc26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGSFFSRLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVAPVCPEACSCSPGGKANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAFKQCTQSLAARDLAVVYALGPASFLASLAICLALGSVLTACGARRRRRRTTVRHLIRRQPDPEGPASLEDVGSPTTTAIQA", "length": 334 }, "evidence": [ { "id": "A0A8V1AJ21", "url": "https://omabrowser.org/oma/group/A0A8V1AJ21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91W20-1", "protein_name": "Leucine-rich repeat-containing protein 26", "gene_name": "Lrrc26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGSFFSRLPPQLSLLLLLSLRRVWTQEDIGTAPSKSPVAPECPEACSCSLGGKANCSALALPAVPADLSWQVRSLLLDHNRVSALPPGAFANAGALLYLDLRENRLRSVHARAFWGLGVLQWLDLSSNQLETLPPGTFAPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSAIEAGLLNNLPALDVLRLHGNPWTCNCALRPLCTWLRKHPRPASETETLLCVSPRLQTLSLLTAFPDAAFKQCTQSLAARDLAVVYALGPVSFLASLAICLALGSVLTACGARRRRRRRTTVRHLLRRQLDPEGPPSLEDAGSPVTAAIQA", "length": 331 }, "evidence": [ { "id": "A0A8V1AJ21", "url": "https://omabrowser.org/oma/group/A0A8V1AJ21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" } ], "pmid": "" }, { "name": "potassium channel activator activity", "id": "GO:0099104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 264, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AJ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ21" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 109, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 257, "end_pos": 259 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJ40-1", "uniprot_ac": "A0A8V1AJ40", "uniprot_id": "A0A8V1AJ40_CHICK", "mass": { "chemical_mass": 30011.0, "monoisotopic_mass": 30011.0 }, "refseq": { "ac": "XP_040505906", "name": "transmembrane protein 220 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505906" }, "gene_names": [ { "name": "TMEM220", "type": "recommended", "evidence": [ { "id": "A0A8V1AJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40" } ] }, { "name": "TMEM220", "type": "synonym", "evidence": [ { "id": "XP_040505906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505906" } ] } ], "protein_names": [ { "name": "Transmembrane protein 220", "type": "synonym", "evidence": [ { "id": "A0A8V1AJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 220 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040505906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505906" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505906" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM220", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40", "locus": { "chromosome": "18", "start_pos": 1315491, "end_pos": 1322633, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029569", "url": "https://www.ensembl.org/id/ENSGALG00010029569" } ] } } ], "crossref": [ { "id": "A0A8V1AJ40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ40", "database": "AlphaFoldDB", "categories": [] }, { "id": "417311", "url": "https://www.ncbi.nlm.nih.gov/gene/417311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADQ0", "url": "https://www.orthodb.org/?gene=A0A8V1ADQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ33", "url": "https://www.orthodb.org/?gene=A0A8V1AJ33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ40", "url": "https://www.orthodb.org/?gene=A0A8V1AJ40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKU5", "url": "https://www.orthodb.org/?gene=A0A8V1AKU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMQ1", "url": "https://www.orthodb.org/?gene=A0A8V1AMQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP79", "url": "https://www.orthodb.org/?gene=A0A8V1AP79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34262", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34262", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34262:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34262:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505906", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSTTSAHLQNTPRGEDSPGQFASQKSYCKHRNVGMRDVRTALVQHPTRSTNSAYASLGNLQGRRSRSPPRHPLPAARPRQDEWQPAPPSGRGQPAPLPAEAESRAVMEACRSVGLLWRLCNLLMAAFFGLAAAVQVNDPDAGLWVVVYLVPAALTLLVVLNPLVTENFFWRSLCDLHSAGCIIGTISLAYSLFAYTQGNILHEEEGRELFGLVIITTWMSLCRSSAKNPLGGIHLTAAILVALFPFVSWLYIYMNKEMRESWPEHCKTVI", "length": 272, "header": "tr|A0A8V1AJ40-1|A0A8V1AJ40_CHICK Isoform 1 of Transmembrane protein 220 OS=Gallus gallus OX=9031 GN=TMEM220 PE=4 SV=1 CANONICAL=A0A8V1AJ40-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40/entry#A0A8V1ADQ0-1", "sequence": { "sequence": "MPLGGAPVEALQPAYGRLLRAGGRRAGERPRCRAVGENFFWRSLCDLHSAGCIIGTISLAYSLFAYTQGNILHEEEGRNPLGGIHLTAAILVALFPFVSWLYIYMNKEMRESWPEHCKTVI", "length": 121, "header": "tr|A0A8V1ADQ0-1|A0A8V1ADQ0_CHICK Computationally mapped isoform of Transmembrane protein 220 OS=Gallus gallus OX=9031 GN=TMEM220 PE=4 SV=1 CANONICAL=A0A8V1AJ40-1" }, "locus": { "chromosome": "18", "start_pos": 1322024, "end_pos": 1316682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071461.1", "url": "https://www.ensembl.org/id/ENSGALT00010071461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044151.1", "url": "https://www.ensembl.org/id/ENSGALP00010044151.1" } ] } }, { "isoform_ac": "A0A8V1AJ33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40/entry#A0A8V1AJ33-1", "sequence": { "sequence": "MSLSLSLKHQSPALRQRCQCCSQSPAKGQMEACQGARRQTLLVPWCLLSTTGQRENFFWRSLCDLHSAGCIIGTISLAYSLFAYTQGNILHEEEGRELFGLVIITTWMSLCRSSAKNPLGGIHLTAAILVALFPFVSWLYIYMNKEMRESWPEHCKTVI", "length": 159, "header": "tr|A0A8V1AJ33-1|A0A8V1AJ40_CHICK Computationally mapped isoform of Transmembrane protein 220 OS=Gallus gallus OX=9031 GN=TMEM220 PE=4 SV=1 CANONICAL=A0A8V1AJ40-1" }, "locus": { "chromosome": "18", "start_pos": 1319153, "end_pos": 1316682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071458.1", "url": "https://www.ensembl.org/id/ENSGALT00010071458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044148.1", "url": "https://www.ensembl.org/id/ENSGALP00010044148.1" } ] } }, { "isoform_ac": "A0A8V1AJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40/entry#A0A8V1AJ40-1", "sequence": { "sequence": "MSLSTTSAHLQNTPRGEDSPGQFASQKSYCKHRNVGMRDVRTALVQHPTRSTNSAYASLGNLQGRRSRSPPRHPLPAARPRQDEWQPAPPSGRGQPAPLPAEAESRAVMEACRSVGLLWRLCNLLMAAFFGLAAAVQVNDPDAGLWVVVYLVPAALTLLVVLNPLVTENFFWRSLCDLHSAGCIIGTISLAYSLFAYTQGNILHEEEGRELFGLVIITTWMSLCRSSAKNPLGGIHLTAAILVALFPFVSWLYIYMNKEMRESWPEHCKTVI", "length": 272, "header": "tr|A0A8V1AJ40-1|A0A8V1AJ40_CHICK Isoform 1 of Transmembrane protein 220 OS=Gallus gallus OX=9031 GN=TMEM220 PE=4 SV=1 CANONICAL=A0A8V1AJ40-1" }, "locus": { "chromosome": "18", "start_pos": 1322434, "end_pos": 1316682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071463.1", "url": "https://www.ensembl.org/id/ENSGALT00010071463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044153.1", "url": "https://www.ensembl.org/id/ENSGALP00010044153.1" } ] } }, { "isoform_ac": "A0A8V1AKU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ40/entry#A0A8V1AKU5-1", "sequence": { "sequence": 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"MAASPSLRPRAARPSPGGGGEPCRHGGMPLGGAPVEALQPAYGRLLRAGGRRAGERPRCRAVGENFFWRSLCDLHSAGCIIGTISLAYSLFAYTQGNILHEEEGRELFGLVIITTWMSLCRSSAKNPLGGIHLTAAILVALFPFVSWLYIYMNKEMRESWPEHCKTVI", "length": 168, "header": "tr|A0A8V1AP79-1|A0A8V1AP79_CHICK Computationally mapped isoform of Transmembrane protein 220 OS=Gallus gallus OX=9031 GN=TMEM220 PE=4 SV=1 CANONICAL=A0A8V1AJ40-1" }, "locus": { "chromosome": "18", "start_pos": 1322105, "end_pos": 1316682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071462.1", "url": "https://www.ensembl.org/id/ENSGALT00010071462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044152.1", "url": "https://www.ensembl.org/id/ENSGALP00010044152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"LOC124417394", "type": "synonym", "evidence": [ { "id": "XP_046759956", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759956" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AJ36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ36/entry#names_and_taxonomy" } ] }, { "name": "claw keratin-like", "type": "synonym", "evidence": [ { "id": "XP_046759956", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759956" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759956" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ36" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC124417394", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ36", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJ36", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ36", "database": "AlphaFoldDB", "categories": [] }, { "id": "124417394", "url": "https://www.ncbi.nlm.nih.gov/gene/124417394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SAIMVEY", "url": "https://omabrowser.org/oma/group/SAIMVEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ36", "url": "https://www.orthodb.org/?gene=A0A8V1AJ36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046759956", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759956", "database": "RefSeq", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJ39-1", "uniprot_ac": "A0A8V1AJ39", "uniprot_id": "A0A8V1AJ39_CHICK", "mass": { "chemical_mass": 36663.0, "monoisotopic_mass": 36663.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121106470", "type": "recommended", "evidence": [ { "id": "A0A8V1AJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39" } ] } ], "protein_names": [ { "name": "Deaminated glutathione amidase", "type": "recommended", "evidence": [ { "id": "A0A8V1AJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.128", "type": "synonym", "evidence": [ { "id": "A0A8V1AJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39/entry#names_and_taxonomy" } ] }, { "name": "Nitrilase homolog 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106470", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJ39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ39", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07572", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07572", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A737", "url": "https://www.orthodb.org/?gene=A0A8V1A737", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ39", "url": "https://www.orthodb.org/?gene=A0A8V1AJ39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23088", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23088", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23088:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23088:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00795", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00795", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A737", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A737", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A737-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A737-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGPRGQSEGVLLAVRRCWLSAVLRLPLHRFCAGPRSPLGSHQAMAASLGPKPLVAVGQVTSTPDKEQNFSGCAALVRAAARRGACLVFLPEGFDYIGRDSAQTLSLAESLDGDLMVRYSTLARDCGVWLSLGGFHERRADWPSTQRIYNCHVLLDPTGRLAAAYRKTHLCDVELEGRVTMKESSFTNPGTEIVPPISTPAGMLGLSICYDLRFPEISLALRHAGAEILTYPSAFTFPTGSAHWEVLLRARAIETQCYVVAAAQTGRNHEGRVSYGHTLVADPWGAVVAQCSEGPGLCYAEIDLEYLRRVRREIPVQSHRRADLYGTVGLQAALSVP", "length": 337, "header": "tr|A0A8V1AJ39-1|A0A8V1AJ39_CHICK Isoform 1 of Deaminated glutathione amidase OS=Gallus gallus OX=9031 GN=LOC121106470 PE=3 SV=1 CANONICAL=A0A8V1AJ39-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A737-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39/entry#A0A8V1A737-1", "sequence": { "sequence": "MYGPRGQSEGVLLAVRSHQAMAASLGPKPLVAVGQVTSTPDKEQNFSGCAALVRAAARRGACLVFLPEGFDYIGRDSAQTLSLAESLDGDLMVRYSTLARDCGVWLSLGGFHERRADWPSTQRIYNCHVLLDPTGRLAAAYRKTHLCDVELEGRVTMKESSFTNPGTEIVPPISTPAGMLGLSICYDLRFPEISLALRHAGAEILTYPSAFTFPTGSAHWEVSVNCNPTPQ", "length": 231, "header": "tr|A0A8V1A737-1|A0A8V1A737_CHICK Computationally mapped isoform of CN hydrolase domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121106470 PE=4 SV=1 CANONICAL=A0A8V1AJ39-1" }, "locus": { "chromosome": "25", "start_pos": 2957089, "end_pos": 2955019, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067998.1", "url": "https://www.ensembl.org/id/ENSGALT00010067998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041741.1", "url": "https://www.ensembl.org/id/ENSGALP00010041741.1" } ] } }, { "isoform_ac": "A0A8V1AJ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39/entry#A0A8V1AJ39-1", "sequence": { "sequence": "MYGPRGQSEGVLLAVRRCWLSAVLRLPLHRFCAGPRSPLGSHQAMAASLGPKPLVAVGQVTSTPDKEQNFSGCAALVRAAARRGACLVFLPEGFDYIGRDSAQTLSLAESLDGDLMVRYSTLARDCGVWLSLGGFHERRADWPSTQRIYNCHVLLDPTGRLAAAYRKTHLCDVELEGRVTMKESSFTNPGTEIVPPISTPAGMLGLSICYDLRFPEISLALRHAGAEILTYPSAFTFPTGSAHWEVLLRARAIETQCYVVAAAQTGRNHEGRVSYGHTLVADPWGAVVAQCSEGPGLCYAEIDLEYLRRVRREIPVQSHRRADLYGTVGLQAALSVP", "length": 337, "header": "tr|A0A8V1AJ39-1|A0A8V1AJ39_CHICK Isoform 1 of Deaminated glutathione amidase OS=Gallus gallus OX=9031 GN=LOC121106470 PE=3 SV=1 CANONICAL=A0A8V1AJ39-1" }, "locus": { "chromosome": "25", "start_pos": 2957089, "end_pos": 2954677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010067999.1", "url": "https://www.ensembl.org/id/ENSGALT00010067999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041742.1", "url": "https://www.ensembl.org/id/ENSGALP00010041742.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "deaminated glutathione amidase activity", "id": "GO:0110050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ39" }, { "id": "PS50263", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50263" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CN hydrolase", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 304, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.128", "ec_name": "N-(4-oxoglutaryl)-L-cysteinylglycine + H2O = L-cysteinylglycine + 2-oxoglutarate.", "evidence": [ { "id": "3.5.1.128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.128" }, { "id": "3.5.1.128", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.128" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJ62-1", "uniprot_ac": "A0A8V1AJ62", "uniprot_id": "A0A8V1AJ62_CHICK", "mass": { "chemical_mass": 50380.0, "monoisotopic_mass": 50380.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF414", "type": "recommended", "evidence": [ { "id": "A0A8V1AJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62" } ] } ], "protein_names": [ { "name": "Zinc finger protein 414", "type": "synonym", "evidence": [ { "id": "A0A8V1AJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF414", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62", "locus": { "chromosome": "28", "start_pos": 2161609, "end_pos": 2167002, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028544", "url": "https://www.ensembl.org/id/ENSGALG00010028544" } ] } } ], "crossref": [ { "id": "A0A8V1AJ62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJ62", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ62", "url": "https://www.orthodb.org/?gene=A0A8V1AJ62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21695:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21695:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHGSSVPWHVAEGVTFACFGDHTWGGRGGEGGGWLLTPREEQEEVVVAPCCVNPCSSVGCSTTKKRRAPCPAAAMKTEKDEALPNFSLGGKYAGEGAGPMTALGSGGAPPAQDLRLLKRRPAPGKHYACSSYGCRLAFPSMQELMDHLKVHYRPTQSLEGKTFQCPTLGCTETFPSMQDLMAHMKVHYKPNRYFKCENCLLRFRTHRSLFKHLHVCSDRASSPAPPPQRAEKPTLPPASTQEKEPTAKPPPEGLPKPPTVIRHTEKEAITTTPGTDTASSLPELPGSLEALPLVPPAPHPFPLLEPNLFGPPTLTRFSGPPPPPPPSSVPFLSYVHPPVPFSLPTAQPRLRPCSPSHGPSASNAVWKKSQGVSVSPLLPCFGSGVTPGHSSNSRIVWEHTRGRYTCMQCPYSTASREEMTLHIEEHRKNAAPAGRMDTDMDFGVSIASFHSKLTPEMENSLYSQL", "length": 465, "header": "tr|A0A8V1AJ62-1|A0A8V1AJ62_CHICK Isoform 1 of Zinc finger protein 414 OS=Gallus gallus OX=9031 GN=ZNF414 PE=4 SV=1 CANONICAL=A0A8V1AJ62-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62/entry#A0A8V1AJ62-1", "sequence": { "sequence": "MHGSSVPWHVAEGVTFACFGDHTWGGRGGEGGGWLLTPREEQEEVVVAPCCVNPCSSVGCSTTKKRRAPCPAAAMKTEKDEALPNFSLGGKYAGEGAGPMTALGSGGAPPAQDLRLLKRRPAPGKHYACSSYGCRLAFPSMQELMDHLKVHYRPTQSLEGKTFQCPTLGCTETFPSMQDLMAHMKVHYKPNRYFKCENCLLRFRTHRSLFKHLHVCSDRASSPAPPPQRAEKPTLPPASTQEKEPTAKPPPEGLPKPPTVIRHTEKEAITTTPGTDTASSLPELPGSLEALPLVPPAPHPFPLLEPNLFGPPTLTRFSGPPPPPPPSSVPFLSYVHPPVPFSLPTAQPRLRPCSPSHGPSASNAVWKKSQGVSVSPLLPCFGSGVTPGHSSNSRIVWEHTRGRYTCMQCPYSTASREEMTLHIEEHRKNAAPAGRMDTDMDFGVSIASFHSKLTPEMENSLYSQL", "length": 465, "header": "tr|A0A8V1AJ62-1|A0A8V1AJ62_CHICK Isoform 1 of Zinc finger protein 414 OS=Gallus gallus OX=9031 GN=ZNF414 PE=4 SV=1 CANONICAL=A0A8V1AJ62-1" }, "locus": { "chromosome": "28", "start_pos": 2166803, "end_pos": 2163357, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069126.1", "url": "https://www.ensembl.org/id/ENSGALT00010069126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042568.1", "url": "https://www.ensembl.org/id/ENSGALP00010042568.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 386, "start_aa": "Thr", "end_pos": 386, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ62" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 156, "start_aa": "Tyr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 386 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR021935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADS4", "url": "https://www.orthodb.org/?gene=A0A8V1ADS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ63", "url": "https://www.orthodb.org/?gene=A0A8V1AJ63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP93", "url": "https://www.orthodb.org/?gene=A0A8V1AP93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ADS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"header": "tr|A0A8V1ADS4-1|A0A8V1ADS4_CHICK Computationally mapped isoform of Small G protein signaling modulator 2 OS=Gallus gallus OX=9031 GN=SGSM2 PE=3 SV=1 CANONICAL=A0A8V1AJ63-1" }, "locus": { "chromosome": "19", "start_pos": 9847167, "end_pos": 9809119, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071482.1", "url": "https://www.ensembl.org/id/ENSGALT00010071482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044172.1", "url": "https://www.ensembl.org/id/ENSGALP00010044172.1" } ] } }, { "isoform_ac": "A0A8V1AJ63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ63/entry#A0A8V1AJ63-1", "sequence": { "sequence": "MSCSADAAKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGVVEACLLHMLKRRAAGFLRTDKVAALFTKVGKTYAIAGDICKKVQELQQQVESRKNQPNVQEPLKRQGSATSKTPVLTPQAIKHIWVRTALIEKVLDKIVQYIVDNCSKYYEKEALLADPVCGPILASLLVGPCALEYTKLKTADHYWTDPSADELVQRHRIHGVHGRQDSPSKRPALGIRKRHSSGSTSEDRFAASAREYVESLHQNSRTHLLYGKNNVLVQPKDDLEAIPGYLSLHQSADSLTLKWTPNQLMNGTLGDSELEKSVYWDYALIVPLSQIVCIHCHQQRESRWTLVLVSQDGTQKPPLHFPQGGHLLAFLSCLENGLLPRGQLEPPLWSQQGKGKVFPKLRKRNSNKSLDLEEMPAEDTSTDYVFRIIYPGHKHDNITINYHHLAASRSASVDDDEEEEDKLHAMLSMICSRNLTAPNRMKDTSEMIEMQGFGANLLSWQLEHCSQGSSCISCSTGSSPYDIPSCCNCIHDRTPLKMLCESMKRQIVSRAFYGWLAYCRHLSTVRTHLSALVNHTIIPPDKPSSAAGGLTKEVWSKYQKDRKNYKELELLRKVYYGGVQHEIRKEVWPFLLGHYKFGMAKKEMDQVDEEIALRYQKVMAEWKACEVIVKQREKESHSATLAKFSSGSSIDSHVQRLIHRDSTISNDVFISVDETDSAEQDSKCQDDPTFTVVSADTPAAAAAVEQQSVEFDSPDSGLPSSRNYSVASGILSSIDDGQSVSFEEGAEEETSGDMERTDPDTTPMQKAKSAVPQPQDSVAEEQLCSQVDYLMDVASVCAASYTIELLDTVALNLHRIDKDVQRCDRNYWYFTADNLEKLRNVMCSYVWEHLEVGYVQGMCDLLAPLMVILDNDQLAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFTVWEVIWAAKHISSEHFVLFIALALVEVYREIIRDNNMDFTDIIKFFNEMAEHHNAQEILRIARDLVYKVQTLIENK", "length": 1059, "header": "tr|A0A8V1AJ63-1|A0A8V1AJ63_CHICK Isoform 1 of Small G protein signaling modulator 2 OS=Gallus gallus OX=9031 GN=SGSM2 PE=3 SV=1 CANONICAL=A0A8V1AJ63-1" }, "locus": { "chromosome": "19", "start_pos": 9847167, "end_pos": 9803270, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071484.1", "url": "https://www.ensembl.org/id/ENSGALT00010071484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044174.1", "url": "https://www.ensembl.org/id/ENSGALP00010044174.1" } ] } }, { "isoform_ac": "A0A8V1AP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ63/entry#A0A8V1AP93-1", "sequence": { "sequence": "MSCSADAAKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGVVEACLLHMLKRRAAGFLRTDKVAALFTKVGKTYAIAGDICKKVQELQQQVESRKNQPNVQEPLKRQGSATSKTPVLTPQAIKHIWVRTALIEKVLDKIVQYIVDNCSKYYEKEALLADPVCGPILASLLVGPCALEYTKLKTADHYWTDPSADELVQRHRIHGVHGRQDSPSKRPALGIRKRHSSGSTSEDRFAASAREYVESLHQNSRTHLLYGKNNVLVQPKDDLEAIPGYLSLHQSADSLTLKWTPNQLMNGTLGDSELEKSVYWDYALIVPLSQIVCIHCHQQRESRWTLVLVSQDGTQKPPLHFPQGGHLLAFLSCLENGLLPRGQLEPPLWSQQGKGKVFPKLRKRNSNKSLDLEEMPAEDTSTDYVFRIIYPGHKHDNNTSEMIEMQGFGANLLSWQLEHCSQGSSCISCSTGSSPYDIPSCCNCIHDRTPLKMLCESMKRQIVSRAFYGWLAYCRHLSTVRTHLSALVNHTIIPPDKPSSAAGGLTKEVWSKYQKDRKNYKELELLRKVYYGGVQHEIRKEVWPFLLGHYKFGMAKKEMDQVDEEIALRYQKVMAEWKACEVIVKQREKESHSATLAKFSSGSSIDSHVQRLIHRDSTISNDVFISVDETDSAEQDSKCQDDPTFTVVSADTPAAAAAVEQQSVEFDSPDSGLPSSRNYSVASGILSSIDDGQSVSFEEGAEEETSGDMERTDPDTTPMQKAKSAVPQPQDSVAEEQLCSQVDYLMDVASVCAASYTIELLDTVALNLHRIDKDVQRCDRNYWYFTADNLEKLRNVMCSYVWEHLEVGYVQGMCDLLAPLMVILDNDQLAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELLYEDVFTVWEVIWAAKHISSEHFVLFIALALVEVYREIIRDNNMDFTDIIKFFNGKTYFKKDIAINSNYPQSAASPLL", "length": 1009, "header": "tr|A0A8V1AP93-1|A0A8V1AP93_CHICK Computationally mapped isoform of Small G protein signaling modulator 2 OS=Gallus gallus OX=9031 GN=SGSM2 PE=3 SV=1 CANONICAL=A0A8V1AJ63-1" }, "locus": { "chromosome": "19", "start_pos": 9846343, "end_pos": 9803270, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071483.1", "url": "https://www.ensembl.org/id/ENSGALT00010071483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044173.1", "url": "https://www.ensembl.org/id/ENSGALP00010044173.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ63", "url": 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"https://www.uniprot.org/uniprotkb/A0A3Q2TTU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALMCPRPLLRYRSFAILLFAPLLLLPLPITVPTREAKCAYIIIIMAVYWCTEVIPLAVTSLMPVVFFPLLGVQSSKSFRLFSTKKGNRVLESGGSSKAATALSGNVGVRPGALNGFEGKAGSTSETSKRQDLVPLSIFFVLQVCLQYLNDTNMLFVGGLIVAISVERWNLHKRIALRVLLILGVKPALLMLGFMIVTAFLSMWISNTATTAMMVPIVQAVLDQMDNTENDVTMMEQATGQTNTVIELEEKNASDPTPVQVISNGQVPDGTRSSEEKKMKKRICKGMTLCVCYAASIGGTATLTGTGPNMVLKGQMNQLYPDNNDVVNFASWFGFAFPNMILMLVLAWLWLQCSFMGFNFKKSWGCGTVRTAKEKAAYNVLKAEMKKLGPISYAEFNVLVMFALLVLLWFSRHPGFVKGWASRLFPEGEKYITDSAPAVFIALLLFILPANKPKFIGWNSSMSDTEQTEEDIKKPFLSAPLLDWNVVQRKMPWSIVLLLGGGFALADASANSGLSAWLGHQMTPLGSIPPWSIATVLSLIIAVFTECTSNVATATLFLPVFSSMATSVKIHPLYVMLPGTLSASFAFMLPVATPPNAIVFSYGHIRVLDMVRSGIVMNIIGVFCVTLAINTWGRPIFELDTFPTWANSTTNQ", "length": 652, "header": "tr|A0A8V1AJ78-1|A0A8V1AJ78_CHICK Isoform 1 of Solute carrier family 13 member 5 OS=Gallus gallus OX=9031 GN=SLC13A5 PE=3 SV=1 CANONICAL=A0A8V1AJ78-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TTU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78/entry#A0A3Q2TTU5-1", "sequence": { "sequence": "MALMCPRPLLRYRSFAILLFAPLLLLPLPITVPTREAKCAYIIIIMAVYWCTEVIPLAVTSLMPVVFFPLLGVQSSKSFRLFSTKKGNRVLESGGSSKAATALSGNVGVCLQYLNDTNMLFVGGLIVAISVERWNLHKRIALRVLLILGVKPALLMLGFMIVTAFLSMWISNTATTAMMVPIVQAVLDQMDNTENDVTMMEQATGQTNTVIELEEKNASDPTPVQVISNGQVPDGTRSSEEKKMKKRICKGMTLCVCYAASIGGTATLTGTGPNMVLKGQMNQLYPDNNDVVNFASWFGFAFPNMILMLVLAWLWLQCSFMGFNFKKSWGCGTVRTAKEKAAYNVLKAEMKKLGPISYAEFNVLVMFALLVLLWFSRHPGFVKGWASRLFPEGEKYITDSAPAVFIALLLFILPANKPKFIGWNSSMSDTEQTEEDIKKPFLSAPLLDWNVVQRKMPWSIVLLLGGGFALADASANSGLSAWLGHQMTPLGSIPPWSIATVLSLIIAVFTECTSNVATATLFLPVFSSMATSVKIHPLYVMLPGTLSASFAFMLPVATPPNAIVFSYGHIRVLDMVRSGIVMNIIGVFCVTLAINTWGRPIFELDTFPTWANSTTNQ", "length": 617, "header": "tr|A0A3Q2TTU5-1|A0A3Q2TTU5_CHICK Computationally mapped isoform of Solute carrier family 13 member 5 OS=Gallus gallus OX=9031 GN=SLC13A5 PE=3 SV=1 CANONICAL=A0A8V1AJ78-1" }, "locus": { "chromosome": "19", "start_pos": 10274374, "end_pos": 10260242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070787.1", "url": "https://www.ensembl.org/id/ENSGALT00010070787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043478.1", "url": "https://www.ensembl.org/id/ENSGALP00010043478.1" } ] } }, { "isoform_ac": "A0A8V1AJ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78/entry#A0A8V1AJ78-1", "sequence": { "sequence": "MALMCPRPLLRYRSFAILLFAPLLLLPLPITVPTREAKCAYIIIIMAVYWCTEVIPLAVTSLMPVVFFPLLGVQSSKSFRLFSTKKGNRVLESGGSSKAATALSGNVGVRPGALNGFEGKAGSTSETSKRQDLVPLSIFFVLQVCLQYLNDTNMLFVGGLIVAISVERWNLHKRIALRVLLILGVKPALLMLGFMIVTAFLSMWISNTATTAMMVPIVQAVLDQMDNTENDVTMMEQATGQTNTVIELEEKNASDPTPVQVISNGQVPDGTRSSEEKKMKKRICKGMTLCVCYAASIGGTATLTGTGPNMVLKGQMNQLYPDNNDVVNFASWFGFAFPNMILMLVLAWLWLQCSFMGFNFKKSWGCGTVRTAKEKAAYNVLKAEMKKLGPISYAEFNVLVMFALLVLLWFSRHPGFVKGWASRLFPEGEKYITDSAPAVFIALLLFILPANKPKFIGWNSSMSDTEQTEEDIKKPFLSAPLLDWNVVQRKMPWSIVLLLGGGFALADASANSGLSAWLGHQMTPLGSIPPWSIATVLSLIIAVFTECTSNVATATLFLPVFSSMATSVKIHPLYVMLPGTLSASFAFMLPVATPPNAIVFSYGHIRVLDMVRSGIVMNIIGVFCVTLAINTWGRPIFELDTFPTWANSTTNQ", "length": 652, "header": "tr|A0A8V1AJ78-1|A0A8V1AJ78_CHICK Isoform 1 of Solute carrier family 13 member 5 OS=Gallus gallus OX=9031 GN=SLC13A5 PE=3 SV=1 CANONICAL=A0A8V1AJ78-1" }, "locus": { "chromosome": "19", "start_pos": 10274374, "end_pos": 10260242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070786.1", "url": "https://www.ensembl.org/id/ENSGALT00010070786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043477.1", "url": "https://www.ensembl.org/id/ENSGALP00010043477.1" } ] } }, { "isoform_ac": "A0A8V1AMX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78/entry#A0A8V1AMX4-1", "sequence": { "sequence": "MALMCPRPLLRYRSFAILLFAPLLLLPLPITVPTRVCLQYLNDTNMLFVGGLIVAISVERWNLHKRIALRVLLILGVKPALLMLGFMIVTAFLSMWISNTATTAMMVPIVQAVLDQMDNTENDVTMMEQATGQTNTVIELEEKNASDPTPVQVISNGQVPDGTRSSEEKKMKKRICKGMTLCVCYAASIGGTATLTGTGPNMVLKGQMNQLYPDNNDVVNFASWFGFAFPNMILMLVLAWLWLQCSFMGFNFKKSWGCGTVRTAKEKAAYNVLKAEMKKLGPISYAEFNVLVMFALLVLLWFSRHPGFVKGWASRLFPEGEKYITDSAPAVFIALLLFILPANKPKFIGWNSSMSDTEQTEEDIKKPFLSAPLLDWNVVQRKMPWSIVLLLGGGFALADASANSGLSAWLGHQMTPLGSIPPWSIATVLSLIIAVFTECTSNVATATLFLPVFSSMATSVKIHPLYVMLPGTLSASFAFMLPVATPPNAIVFSYGHIRVLDMVRSGIVMNIIGVFCVTLAINTWGRPIFELDTFPTWANSTTNQ", "length": 544, "header": "tr|A0A8V1AMX4-1|A0A8V1AMX4_CHICK Computationally mapped isoform of Solute carrier family 13 member 5 OS=Gallus gallus OX=9031 GN=SLC13A5 PE=3 SV=1 CANONICAL=A0A8V1AJ78-1" }, "locus": { "chromosome": "19", "start_pos": 10274374, "end_pos": 10260242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070788.1", "url": "https://www.ensembl.org/id/ENSGALT00010070788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043479.1", "url": "https://www.ensembl.org/id/ENSGALP00010043479.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9955298", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9955298", "resource": "Reactome", "description": "SLC-mediated transport of organic anions" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9VVT2-1", "protein_name": "Protein I'm not dead yet", "gene_name": "Indy", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATETTKMIYTPPPLDIKMEIEIGEQPQPPVKCSNFFANHWKGLVVFLVPLLCLPVMLLNEGAEFRCMYLLLVMAIFWVTEALPLYVTSMIPIVAFPIMGIMSSDQTCRLYFKDTLVMFMGGIMVALAVEYCNLHKRLALRVIQIVGCSPRRLHFGLIMVTMFLSMWISNAACTAMMCPIIQAVLEELQAQGVCKINHEPQYQIVGGNKKNNEDEPPYPTKITLCYYLGIAYASSLGGCGTIIGTATNLTFKGIYEARFKNSTEQMDFPTFMFYSVPSMLVYTLLTFVFLQWHFMGLWRPKSKEAQEVQRGREGADVAKKVIDQRYKDLGPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLLNSKDIRNSMPTIFVVVMCFMLPANYAFLRYCTRRGGPVPTGPTPSLITWKFIQTKVPWGLVFLLGGGFALAEGSKQSGMAKLIGNALIGLKVLPNSVLLLVVILVAVFLTAFSSNVAIANIIIPVLAEMSLAIEIHPLYLILPAGLACSMAFHLPVSTPPNALVAGYANIRTKDMAIAGIGPTIITIITLFVFCQTWGLVVYPNLNSFPEWAQIYAAAALGNKTH", "length": 590 }, "evidence": [ { "id": "A0A8V1AJ78", "url": "https://omabrowser.org/oma/group/A0A8V1AJ78/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "citrate transport", "id": "GO:0015746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "cellular response to lithium ion", "id": "GO:0071285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "alpha-ketoglutarate transport", "id": "GO:0015742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "oxaloacetate transport", "id": "GO:0015729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "succinate transport", "id": "GO:0015744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015744", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "fumarate transport", "id": "GO:0015741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "citrate transmembrane transporter activity", "id": "GO:0015137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015137", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "sodium:dicarboxylate symporter activity", "id": "GO:0017153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017153", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "succinate transmembrane transporter activity", "id": "GO:0015141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" }, { "name": "solute:sodium symporter activity", "id": "GO:0015370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015370", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 647, "end_pos": 649, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 31 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 647, "end_pos": 649 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL19-1", "uniprot_ac": "A0A8V1AL19", "uniprot_id": "A0A8V1AL19_CHICK", "mass": { "chemical_mass": 18097.0, "monoisotopic_mass": 18097.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100858797", "type": "recommended", "evidence": [ { "id": "A0A8V1AL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL19" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL19", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100858797", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL19", "locus": {} } ], "crossref": [ { "id": "A0A8V1AL19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL19", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEN5", "url": "https://www.orthodb.org/?gene=A0A8V1AEN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ96", "url": "https://www.orthodb.org/?gene=A0A8V1AJ96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL19", "url": "https://www.orthodb.org/?gene=A0A8V1AL19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ96", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ96-1", "database": "UniProtKB", "categories": [ "Protein" 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"MAERVEQRLEDRVPELEQLGRVGLFTHEEIRAVLKKATALEYKIQRRALRKEDFINYIQRTGYSFKKEEIESSIMHRVHSLFKRATGKWKEDVQLWLSHVAFCKQWNAKHQLSKVFSTMLAIHPNKPALWIMAAKWEMETRLSSESARHLFLRALRFHPECPKLYQEYFRMELMNAEKQRKEKKELERAKMNLEEFNYSEKILNGEMAHIIYRDAAQKIKGVEFHLALLSIAKLFDFTHDLQKEILESLQAEYADNPLTWDYMARRELELGSLKSTEPTTKQMKVSEMTQREERCCAVFDEAVTAVPTEDMWKCYITFCLERYNRKTNSEELKQKRLERTLSVFSKAHESSLLPEALYKQWLQLLLESSLSQKAAEVAEAATKRFSLSVEIWQLRLQVLIQLKSDNVTQCFEEAFKHVKSKGTLPLWTLWVEWSEVTNSKEDTEALYQRSLHAVAPAESVTMKEKYLDWAYRSGGYKKVRRVFTSLHESRPLSLDFFRKMIEIEKEQESCKMLHLREYYERALREFGSADSDLWLEYIKEELSHPQGKPENSASIHWRAMKMLQEDQVEDFISKYTLLQTGHI", "length": 583, "header": "tr|A0A8V1AJA3-1|A0A8V1AL12_CHICK Computationally mapped isoform of UTP6, small subunit processome component OS=Gallus gallus OX=9031 GN=UTP6 PE=3 SV=1 CANONICAL=A0A8V1AL12-1" }, "locus": { "chromosome": "18", "start_pos": 7211869, "end_pos": 7202235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071527.1", "url": "https://www.ensembl.org/id/ENSGALT00010071527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044217.1", "url": "https://www.ensembl.org/id/ENSGALP00010044217.1" } ] } }, { "isoform_ac": "A0A8V1AL12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12/entry#A0A8V1AL12-1", "sequence": { "sequence": "MAERVEQRLEDRVPELEQLGRVGLFTHEEIRAVLKKATALEYKIQRRALRKEDFINYIQYEINLLELIKKRRARTGYSFKKEEIESSIMHRVHSLFKRATGKWKEDVQLWLSHVAFCKQWNAKHQLSKVFSTMLAIHPNKPALWIMAAKWEMETRLSSESARHLFLRALRFHPECPKLYQEYFRMELMNAEKQRKEKKELERAKMNLEEFNYSEKILNGEMAHIIYRDAAQKIKGVEFHLALLSIAKLFDFTHDLQKEILESLQAEYADNPLTWDYMARRELELGSLKSTEPTTKQMKVSEMTQREERCCAVFDEAVTAVPTEDMWKCYITFCLERYNRKTNSEELKQKRLERTLSVFSKAHESSLLPEALYKQWLQLLLESSLSQKAAEVAEAATKRFSLSVEIWQLRLQVLIQLKSDNVTQCFEEAFKHVKSKGTLPLWTLWVEWSEVTNSKEDTEALYQRSLHAVAPAESVTMKEKYLDWAYRSGGYKKVRRVFTSLHESRPLSLDFFRKMIEIEKEQESCKMLHLREYYERALREFGSADSDLWLEYIKEELSHPQGKPENSASIHWRAMKMLQEDQVMAATLEHTSLEEEQPPNKKETMTWKPTEVKPKILGQTKADECLLKNILCVLDSDSEGSEFSDISACEDDVSLHTDTDMEDLCGELSRMPEDVTFPQQQTASTYEVEDWDKELEESECSPYDAGDLYCGSFQENNLLASYSFREDSLYNPCCHHAACLAFTLPVRMTEVGQFDDADE", "length": 758, "header": "tr|A0A8V1AL12-1|A0A8V1AL12_CHICK Isoform 1 of UTP6, small subunit processome component OS=Gallus gallus OX=9031 GN=UTP6 PE=3 SV=1 CANONICAL=A0A8V1AL12-1" }, "locus": { "chromosome": "18", "start_pos": 7211869, "end_pos": 7197762, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071529.1", "url": "https://www.ensembl.org/id/ENSGALT00010071529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044219.1", "url": "https://www.ensembl.org/id/ENSGALP00010044219.1" } ] } }, { "isoform_ac": "A0A8V1AMU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12/entry#A0A8V1AMU7-1", "sequence": { "sequence": "MAPCLLSYRAVLKKATALEYKIQRRALRKEDFINYIQYEINLLELIKKRRARTGYSFKKEEIESSIMHRVHSLFKRATGKWKEDVQLWLSHVAFCKQWNAKHQLSKVFSTMLAIHPNKPALWIMAAKWEMETRLSSESARHLFLRALRFHPECPKLYQEYFRMELMNAEKQRKEKKELERAKMNLEEFNYSEKILNGEMAHIIYRDAAQKIKGVEFHLALLSIAKLFDFTHDLQKEILESLQAEYADNPLTWDYMARRELELGSLKSTEPTTKQMKVSEMTQREERCCAVFDEAVTAVPTEDMWKCYITFCLERYNRKTNSEELKQKRLERTLSVFSKAHESSLLPEALYKQWLQLLLESSLSQKAAEVAEAATKRFSLSVEIWQLRLQVLIQLKSDNVTQCFEEAFKHVKSKGTLPLWTLWVEWSEVTNSKEDTEALYQRSLHAVAPAESVTMKEKYLDWAYRSGGYKKVRRVFTSLHESRPLSLDFFRKMIEIEKEQESCKMLHLREYYERALREFGSADSDLWLEYIKEELSHPQGKPENSASIHWRAMKMLQEDQVEDFISKYTLLQTGHI", "length": 575, "header": "tr|A0A8V1AMU7-1|A0A8V1AMU7_CHICK Computationally mapped isoform of UTP6, small subunit processome component OS=Gallus gallus OX=9031 GN=UTP6 PE=3 SV=1 CANONICAL=A0A8V1AL12-1" }, "locus": { "chromosome": "18", "start_pos": 7211722, "end_pos": 7202235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071528.1", "url": "https://www.ensembl.org/id/ENSGALT00010071528.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044218.1", "url": "https://www.ensembl.org/id/ENSGALP00010044218.1" } ] } }, { "isoform_ac": "A0A8V1APC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12/entry#A0A8V1APC1-1", "sequence": { "sequence": "MAATTESLRAVLLVTAMAERVEQRLEDRVPELEQLGRVGLFTHEEIRAVLKKATALEYKIQRRALRKEDFINYIQYEINLLELIKKRRARTGYSFKKEEIESSIMHRVHSLFKRATGKWKEDVQLWLSHVAFCKQWNAKHQLSKVFSTMLAIHPNKPALWIMAAKWEMETRLSSESARHLFLRALRFHPECPKLYQEYFRMELMNAEKQRKEKKELERAKMNLEEFNYSEKILNGEMAHIIYRDAAQKIKGVEFHLALLSIAKLFDFTHDLQKEILESLQAEYADNPLTWDYMARRELELGSLKSTEPTTKQMKVSEMTQREERCCAVFDEAVTAVPTEDMWKCYITFCLERYNRKTNSEELKQKRLERTLSVFSKAHESSLLPEALYKQWLQLLLESSLSQKAAEVAEAATKRFSLSVEIWQLRLQVLIQLKSDNVTQCFEEAFKHVKSKGTLPLWTLWVEWSEVTNSKEDTEALYQRSLHAVAPAESVTMKEKYLDWAYRSGGYKKVRRVFTSLHESRPLSLDFFRKMIEIEKEQESCKMLHLREYYERALREFGSADSDLWLEYIKEELSHPQGKPENSASIHWRAMKMLQEDQVEDFISKYTLLQTGHI", "length": 613, "header": "tr|A0A8V1APC1-1|A0A8V1APC1_CHICK Computationally mapped isoform of UTP6, small subunit processome component OS=Gallus gallus OX=9031 GN=UTP6 PE=3 SV=1 CANONICAL=A0A8V1AL12-1" }, "locus": { "chromosome": "18", "start_pos": 7212442, "end_pos": 7202235, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071526.1", "url": "https://www.ensembl.org/id/ENSGALT00010071526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044216.1", "url": "https://www.ensembl.org/id/ENSGALP00010044216.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" } ], "pmid": "" }, { "name": "Pwp2p-containing subcomplex of 90S preribosome", "id": "GO:0034388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "snoRNA binding", "id": "GO:0030515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" }, { "id": "PF08640", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08640" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 6 N-terminal", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 91, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AL12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL12" }, { "id": "PF24892", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 6 homolog C-terminal", "eco_id": "ECO_0000259", "start_pos": 307, "end_pos": 577, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 420, "end_pos": 422 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJA8-1", "uniprot_ac": "A0A8V1AJA8", "uniprot_id": "A0A8V1AJA8_CHICK", "mass": { "chemical_mass": 78129.0, "monoisotopic_mass": 78129.0 }, "refseq": {}, "gene_names": [ { "name": "APBA3", "type": "recommended", "evidence": [ { "id": "A0A8V1AJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ] } ], "protein_names": [ { "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "type": "recommended", "evidence": [ { "id": "A0A8V1AJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8/entry#names_and_taxonomy" } ] }, { "name": "Adapter protein X11gamma", "type": "synonym", "evidence": [ { "id": "A0A8V1AJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8/entry#names_and_taxonomy" } ] }, { "name": "Neuron-specific X11L2 protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8/entry#names_and_taxonomy" } ] }, { "name": "Neuronal Munc18-1-interacting protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8#function" }, { "database": "UniProtKB", "id": "ARBA00058713", "url": "https://www.uniprot.org/uniprotkb/ARBA00058713#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APBA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8", "locus": { "chromosome": "28", "start_pos": 1405541, "end_pos": 1399081, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028103", "url": "https://www.ensembl.org/id/ENSGALG00010028103" } ] } } ], "crossref": [ { "id": "A0A8V1AJA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01208", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01208", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06720", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06720", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJA8", "url": "https://www.orthodb.org/?gene=A0A8V1AJA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12345:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12345:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGWDTGMGCGKRTQVGHRTGHGNRTRAHDTGMDFQPALDLPAMDTEEGQHVAPQPTAAEGQLEGPTFSGTAVDQQRSAEPGSGPASATNLNSGDERSGLCRNSGREMEEEAVTTGPQGPTDWRLRAGSTSRDTGPPRTPSSGTMELDEAPEEEPSEMQGLLAQLETLNPSLCDAPNTAPGVGERGYAECRGECQPCPLHVATGRGLAVRPCCAQHSARSRPCHGLLFAEADREDLLNLLCYEGGLPEPDTETPLTRSEVLTGTKLEMLQTPEEHSAADGPGGLGSSEERPSGSWICGDGLSEDKPTCEGSRDSSPEPAWTELSPAVTPEKERPPQSSVTNKESPSSCLAFKEVPGPCDPEDLLDGVIFGAKYLGSTQLVSERNPPTSVRMAQAQEAVDRIKAPEGESQPMTEVDLFVSTQRIKVLTADTQEAMMDHSLQTISYIADIGSLVVLMARRKLPRRAEAAEEKRLYKMICHVFHSADAQIIAQAIGQAFGVAYQRFLEANSIDPSELSPRQYSRALEDQEQHNAELTHFSRQENCKDVYIRKQKGEILGIAVVESGWGSILPTVVIANLMHGGPAERSGELSIGDRLMSINGTSLVGLPLTTCQSIIRELKHQTEVMLNIVHCSPVTTAVIRRPDSKYQLGFCVENGVICSLMRGGIAEKGGIRVGHRIIEINGQSVVATPHEKIIQILTQAVSEVHIKTMPASTYRLLTGQEQPVFL", "length": 725, "header": "tr|A0A8V1AJA8-1|A0A8V1AJA8_CHICK Isoform 1 of Amyloid-beta A4 precursor protein-binding family A member 3 OS=Gallus gallus OX=9031 GN=APBA3 PE=4 SV=1 CANONICAL=A0A8V1AJA8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8/entry#A0A8V1AJA8-1", "sequence": { "sequence": "MGGWDTGMGCGKRTQVGHRTGHGNRTRAHDTGMDFQPALDLPAMDTEEGQHVAPQPTAAEGQLEGPTFSGTAVDQQRSAEPGSGPASATNLNSGDERSGLCRNSGREMEEEAVTTGPQGPTDWRLRAGSTSRDTGPPRTPSSGTMELDEAPEEEPSEMQGLLAQLETLNPSLCDAPNTAPGVGERGYAECRGECQPCPLHVATGRGLAVRPCCAQHSARSRPCHGLLFAEADREDLLNLLCYEGGLPEPDTETPLTRSEVLTGTKLEMLQTPEEHSAADGPGGLGSSEERPSGSWICGDGLSEDKPTCEGSRDSSPEPAWTELSPAVTPEKERPPQSSVTNKESPSSCLAFKEVPGPCDPEDLLDGVIFGAKYLGSTQLVSERNPPTSVRMAQAQEAVDRIKAPEGESQPMTEVDLFVSTQRIKVLTADTQEAMMDHSLQTISYIADIGSLVVLMARRKLPRRAEAAEEKRLYKMICHVFHSADAQIIAQAIGQAFGVAYQRFLEANSIDPSELSPRQYSRALEDQEQHNAELTHFSRQENCKDVYIRKQKGEILGIAVVESGWGSILPTVVIANLMHGGPAERSGELSIGDRLMSINGTSLVGLPLTTCQSIIRELKHQTEVMLNIVHCSPVTTAVIRRPDSKYQLGFCVENGVICSLMRGGIAEKGGIRVGHRIIEINGQSVVATPHEKIIQILTQAVSEVHIKTMPASTYRLLTGQEQPVFL", "length": 725, "header": "tr|A0A8V1AJA8-1|A0A8V1AJA8_CHICK Isoform 1 of Amyloid-beta A4 precursor protein-binding family A member 3 OS=Gallus gallus OX=9031 GN=APBA3 PE=4 SV=1 CANONICAL=A0A8V1AJA8-1" }, "locus": { "chromosome": "28", "start_pos": 1404656, "end_pos": 1399133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068092.1", "url": "https://www.ensembl.org/id/ENSGALT00010068092.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041835.1", "url": "https://www.ensembl.org/id/ENSGALP00010041835.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" }, { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 544, "end_pos": 629, "start_aa": "Asp", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA8" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 511, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 }, { "start_pos": 598, "end_pos": 600 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJD3-1", "uniprot_ac": "A0A8V1AJD3", "uniprot_id": "A0A8V1AJD3_CHICK", "mass": { "chemical_mass": 58104.0, "monoisotopic_mass": 58104.0 }, "refseq": {}, "gene_names": [ { "name": "KCNN1", "type": "recommended", "evidence": [ { "id": "A0A8V1AJD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ] } ], "protein_names": [ { "name": "Potassium calcium-activated channel subfamily N member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AJD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3", "locus": { "chromosome": "28", "start_pos": 3806320, "end_pos": 3800789, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028573", "url": "https://www.ensembl.org/id/ENSGALG00010028573" } ] } } ], "crossref": [ { "id": "A0A8V1AJD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJD3", "url": "https://www.orthodb.org/?gene=A0A8V1AJD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL57", "url": "https://www.orthodb.org/?gene=A0A8V1AL57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296052", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296052", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL57", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGPRRNGGVPSASPRSPPPLEAQSPALRPRRAPGLEVVVQPPAPPGRGDAAEGRGGPRRNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTVILLGLIVMYHAREIQLFMVDNGADDWRIAMTYERIFFIALELLVCAIHPIPGQYLFTWTARLAFTYAASVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMVSELQERNEDLEKRISALEGKLEALGLSLLALPALVSQAIGQQQRELLGSWAPRLCPATAPCTPARRRRSPSTAPHSSSDSG", "length": 521, "header": "tr|A0A8V1AJD3-1|A0A8V1AJD3_CHICK Isoform 1 of Potassium calcium-activated channel subfamily N member 1 OS=Gallus gallus OX=9031 GN=KCNN1 PE=4 SV=1 CANONICAL=A0A8V1AJD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3/entry#A0A8V1AJD3-1", "sequence": { "sequence": "MSGPRRNGGVPSASPRSPPPLEAQSPALRPRRAPGLEVVVQPPAPPGRGDAAEGRGGPRRNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESSYSFALKCLISLSTVILLGLIVMYHAREIQLFMVDNGADDWRIAMTYERIFFIALELLVCAIHPIPGQYLFTWTARLAFTYAASVADADVDIILSIPMFLRLYLIGRVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMVSELQERNEDLEKRISALEGKLEALGLSLLALPALVSQAIGQQQRELLGSWAPRLCPATAPCTPARRRRSPSTAPHSSSDSG", "length": 521, "header": "tr|A0A8V1AJD3-1|A0A8V1AJD3_CHICK Isoform 1 of Potassium calcium-activated channel subfamily N member 1 OS=Gallus gallus OX=9031 GN=KCNN1 PE=4 SV=1 CANONICAL=A0A8V1AJD3-1" }, "locus": { "chromosome": "28", "start_pos": 3805316, "end_pos": 3801225, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069207.1", "url": "https://www.ensembl.org/id/ENSGALT00010069207.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042649.1", "url": "https://www.ensembl.org/id/ENSGALP00010042649.1" } ] } }, { "isoform_ac": "A0A8V1AL57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3/entry#A0A8V1AL57-1", "sequence": { "sequence": "MPYQPLHRHPAGAHSHVPRQGDPALHGGQRGGRLAHRHDLRAHLLHRSGAAGLRHPPHPRAVPVHLDGTFGLHLRRFGGRRRRGHHPVHPHVPSALPDRARHAAAQQALHRRVVAQHRRPQQDQLQHPLCHEDPHDHLPRHRALGLQHLLLDHRRLDRPRLREVPRQAGGDQQLPGGHVAHLHHLPLHRLRGHGAAHLLREGGLSAHRHHGRRLHGSGRRRGCQKARAHQSRETRAQLHDGYAANQAGEKRCCQRTQGNVAHLQTHQAGEEDRPCQSSETPAAQKLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMVSELQERNEDLEKRISALEGKLEALGLSLLALPALVSQAIGQQQRELLGSWAPRLCPATAPCTPARRRRSPSTAPHSSSDSG", "length": 398, "header": "tr|A0A8V1AL57-1|A0A8V1AL57_CHICK Computationally mapped isoform of Potassium calcium-activated channel subfamily N member 1 OS=Gallus gallus OX=9031 GN=KCNN1 PE=4 SV=1 CANONICAL=A0A8V1AJD3-1" }, "locus": { "chromosome": "28", "start_pos": 3805316, "end_pos": 3801654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069205.1", "url": "https://www.ensembl.org/id/ENSGALT00010069205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042647.1", "url": "https://www.ensembl.org/id/ENSGALP00010042647.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1296052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296052", "resource": "Reactome", "description": "Ca2+ activated K+ channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" }, { "name": "small conductance calcium-activated potassium channel activity", "id": "GO:0016286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" }, { "name": "inward rectifier potassium channel activity", "id": "GO:0005242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD3" }, { "id": "SM01053", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calmodulin-binding", "eco_id": "ECO_0000259", "start_pos": 359, "end_pos": 435, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJD6-1", "uniprot_ac": "A0A8V1AJD6", "uniprot_id": "A0A8V1AJD6_CHICK", "mass": { "chemical_mass": 28970.0, "monoisotopic_mass": 28970.0 }, "refseq": {}, "gene_names": [ { "name": "ENDOV", "type": "recommended", "evidence": [ { "id": "A0A8V1AJD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ] } ], "protein_names": [ { "name": "Endonuclease V", "type": "synonym", "evidence": [ { "id": "A0A8V1AJD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENDOV", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6", "locus": { "chromosome": "18", "start_pos": 10116001, "end_pos": 10124552, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029298", "url": "https://www.ensembl.org/id/ENSGALG00010029298" } ] } } ], "crossref": [ { "id": "A0A8V1AJD6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJD6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06559", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06559", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJD6", "url": "https://www.orthodb.org/?gene=A0A8V1AJD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALG5", "url": "https://www.orthodb.org/?gene=A0A8V1ALG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28511:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28511:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAETVPKAVPAATLRRWECEQDRLRAAVVPEDTERWQREPGWAGLQRVGGVDLSYVKGGDGSACASLVVLGYPGLEVLYEDCRMVAVSAPYVAGFLAFREVPFMVEAVERLQREQPGLRPQVLLVDGNGLLHQRGFGVACHLGVLTDLPCVGVAKNLLHVDGLVKDELHKEQVKPDSFPAEERRYFPSDRHFRGCPWPCEAATTALNLCISLWATGYAWRQLCVSSSPAASTGSQSPSARLTLDRGRIFRSRCVPHQRSYLPG", "length": 263, "header": "tr|A0A8V1AJD6-1|A0A8V1AJD6_CHICK Isoform 1 of Endonuclease V OS=Gallus gallus OX=9031 GN=ENDOV PE=4 SV=1 CANONICAL=A0A8V1AJD6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6/entry#A0A8V1AJD6-1", "sequence": { "sequence": "MAETVPKAVPAATLRRWECEQDRLRAAVVPEDTERWQREPGWAGLQRVGGVDLSYVKGGDGSACASLVVLGYPGLEVLYEDCRMVAVSAPYVAGFLAFREVPFMVEAVERLQREQPGLRPQVLLVDGNGLLHQRGFGVACHLGVLTDLPCVGVAKNLLHVDGLVKDELHKEQVKPDSFPAEERRYFPSDRHFRGCPWPCEAATTALNLCISLWATGYAWRQLCVSSSPAASTGSQSPSARLTLDRGRIFRSRCVPHQRSYLPG", "length": 263, "header": "tr|A0A8V1AJD6-1|A0A8V1AJD6_CHICK Isoform 1 of Endonuclease V OS=Gallus gallus OX=9031 GN=ENDOV PE=4 SV=1 CANONICAL=A0A8V1AJD6-1" }, "locus": { "chromosome": "18", "start_pos": 10124534, "end_pos": 10117363, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070853.1", "url": "https://www.ensembl.org/id/ENSGALT00010070853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043544.1", "url": "https://www.ensembl.org/id/ENSGALP00010043544.1" } ] } }, { "isoform_ac": "A0A8V1ALG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6/entry#A0A8V1ALG5-1", "sequence": { "sequence": "MVAVSAPYVAGFLAFREVPFMVEAVERLQREQPGLRPQVLLVDGNGLLHQRGFGVACHLGVLTDLPCVGVAKNLLHVDGLVKDELHKEQVKPDSFPAEERRYFPSDRHFRGCPWYGPARLQQQL", "length": 124, "header": "tr|A0A8V1ALG5-1|A0A8V1ALG5_CHICK Computationally mapped isoform of Endonuclease V OS=Gallus gallus OX=9031 GN=ENDOV PE=4 SV=1 CANONICAL=A0A8V1AJD6-1" }, "locus": { "chromosome": "18", "start_pos": 10123706, "end_pos": 10122320, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070852.1", "url": "https://www.ensembl.org/id/ENSGALT00010070852.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043543.1", "url": "https://www.ensembl.org/id/ENSGALP00010043543.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" }, { "name": "DNA endonuclease activity, producing 5'-phosphomonoesters", "id": "GO:0016888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" }, { "name": "RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism", "id": "GO:0016891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJE2-1", "uniprot_ac": "A0A8V1AJE2", "uniprot_id": "A0A8V1AJE2_CHICK", "mass": { "chemical_mass": 119963.0, "monoisotopic_mass": 119963.0 }, "refseq": {}, "gene_names": [ { "name": "GOLGA2", "type": "recommended", "evidence": [ { "id": "A0A8V1AJE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2" } ] } ], "protein_names": [ { "name": "Golgin A2", "type": "synonym", "evidence": [ { "id": "A0A8V1AJE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLGA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR024858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7F2", "url": "https://www.orthodb.org/?gene=A0A8V1A7F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACC7", "url": "https://www.orthodb.org/?gene=A0A8V1ACC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACD2", "url": "https://www.orthodb.org/?gene=A0A8V1ACD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF58", "url": "https://www.orthodb.org/?gene=A0A8V1AF58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF62", "url": "https://www.orthodb.org/?gene=A0A8V1AF62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJE2", "url": "https://www.orthodb.org/?gene=A0A8V1AJE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10881", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10881", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10881:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10881:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15070", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162658", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162658", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A7F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADGSRQSKLAAAKKKLKEYQQKNSPGATAGAKKKRKAKEGSRPETPTNDDRQSPENIQNILKVLVSDLNRSNGVAIPSLDKRKAYFDSDVATRNADQLAADVPVLSNSNSLPSCASVLPAPGSTQLTQIHEAEDRKNTLDENRSLSSTESLRQLSEQLNGLVAQSTSYVNGESGVSSTNIKEMETRYQELAVALDSSNLTNKQLITKIEELKQQNQEAVNQLEKEKKEFEQKFSKEQAALREQLQVHIQTIGILVSEKSELQTALGHTQQAARQKSGEAEDLAARLQSSRQRVSELERTLSSISMQQKQSEKHNKELVKERDNLKLELYKQSKGSEEIKQQNSELSEKLRSVVSENSAMKLDVEDLHKKLEMAELMIQQFSNHTGNVDANQQLQMALEERASLETQITQLSESLHQLRAERDQYVEKLKEEGSIWQQRVQQLSEQVRTMAEEKEKHVAQIQELESNVTELLSKSAVKPMDVEPSLPAGPTAAELSLQEEIKRLQHEKEELHGQYQAQVRDNEQLSHLNQEQEERLLELEKTVQRYNEESVDRQQILESMQSDKATISRALSQNRELKEQLAELQNGFVKLTNENMEVTSALQSEQHVKKELAKKLGQLQENLGELKETLELKTQEARALQEQRDQYYGHLQQYTVAYQQLAAEREELQKQYLLQTQLMDRLQHEEVQGKVTVEMHLKELQQTKESLEAVAKENKELQAQISQLAAELDGRMLHRLDGDGVESEVMSEEMKNPSFVIPEKFESHEEMVTFLTSAMSQVEKEREEMRQQLAVQKQQCRNLLQQIAALRQEQQHNITLSEDSTMDSVPVEVHEALKTAMEKLQSRFTDLIQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQSQRAILKQRHQEKEEYISRLAQDKEEMKIKLLELQDLVMRLVKERNEWYSKYVAAAQSPELLASQNEKALPVERRIELNATDGEGLREVNLADEAEQDAAALHQSSFYPTDTKAAQPSQEDPTAKQIMQLLREIQNPQERSGSLLENPCIPFFYRADENDEVKIMVV", "length": 1050, "header": "tr|A0A8V1AJE2-1|A0A8V1AJE2_CHICK Isoform 1 of Golgin A2 OS=Gallus gallus OX=9031 GN=GOLGA2 PE=1 SV=1 CANONICAL=A0A8V1AJE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2/entry#A0A8V1A7F2-1", "sequence": { "sequence": "MDEVKQAYFDSDVATRNADQLAADVPVLSNSNSLPSCASVLPAPGSTQLTQIHEAEDRKNTLDENRSLSSTESLRQLSEQLNGLVAQSTSYVNGESGVSSTNIKEMETRYQELAVALDSSNLTNKQLITKIEELKQQNQEAVNQLEKEKKEFEQKFSKEQAALREQLQVHIQTIGILVSEKSELQTALGHTQQAARQKSGEAEDLAARLQSSRQRVSELERTLSSISMQQKQSEKHNKELVKERDNLKLELYKQSKGSEEIKQQNSELSEKLRSVVSENSAMKLDVEDLHKKLEMAELMIQQFSNHTGNVDANQQLQMALEERASLETQITQLSESLHQLRAERDQYVEKLKEEGSIWQQRVQQLSEQVRTMAEEKEKHVAQIQELESNVTELLSKSAVKPMDVEPSLPAGPTAAELSLQEEIKRLQHEKEELHGQYQAQVRDNEQLSHLNQEQEERLLELEKTVQRYNEESVDRQQILESMQSDKATISRALSQNRELKEQLAELQNGFVKLTNENMEVTSALQSEQHVKKELAKKLGQLQENLGELKETLELKTQEARALQEQRDQYYGHLQQYTVAYQQLAAEREELQKQYLLQTQLMDRLQHEEVQGKVTVEMHLKELQQTKESLEAVAKENKELQAQISQLAAELDGRMLHRLDGDGVESEVMSEEMKNPSFVIPEKFESHEEMVTFLTSAMSQVEKEREEMRQQLAVQKQQCRNLLQQIAALRQEQQHNITLSEDSTMDSVPVEVHEALKTAMEKLQSRFTDLIQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQSQRAILKQRHQEKEEYISRLAQDKEEMKIKLLELQDLVMRLVKERNEWYSKYVAAAQSPELLASQNEKALPVERRIELNATDGEGLREVNLADEAEQDAAALHQSSFYPTDTKAAQPSQEDPTAKQIMQLLREIQNPQERSGSLLENPCIPFFYRADENDEVKIMVV", "length": 972, "header": "tr|A0A8V1A7F2-1|A0A8V1A7F2_CHICK Computationally mapped isoform of Golgin A2 OS=Gallus gallus OX=9031 GN=GOLGA2 PE=1 SV=1 CANONICAL=A0A8V1AJE2-1" }, "locus": { "chromosome": "17", "start_pos": 5688011, "end_pos": 5673185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068131.1", "url": "https://www.ensembl.org/id/ENSGALT00010068131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041874.1", "url": "https://www.ensembl.org/id/ENSGALP00010041874.1" } ] } }, { "isoform_ac": "A0A8V1ACC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2/entry#A0A8V1ACC7-1", "sequence": { "sequence": "MLTVDAFWLDFRLSFFPPQLKEYQQKNSPGATAGAKKKRKAKEGSRPETPTNDDRQSPENIQNILKVLVSDLNRSNGVAIPSLDKRKIHEAEDRKNTLDENRSLSSTESLRQLSEQLNGLVAQSTSYVNGESGVSSTNIKEMEKQQNQEAVNQLEKEKKEFEQKFSKEQAALREQLQVHIQTIGILVSEKSELQTALGHTQQAARQKSGEAEDLAARLQSSRQRVSELERTLSSISMQQKQSEKHNKELVKERDNLKLELYKQSKGSEEIKQQNSELSEKLRSVVSENSAMKLDVEDLHKKLEMAELMIQQFSNHTGNVDANQQLQMALEERASLETQITQLSESLHQLRAERDQYVEKLKEEGSIWQQRVQQLSEQVRTMAEEKEKHVAQIQELESNVTELLSKSAVKPMDVEPSLPAGPTAAELSLQEEIKRLQHEKEELHGQYQAQVRDNEQLSHLNQEQEERLLELEKTVQRYNEESVDRQQILESMQSDKATISRALSQNRELKEQLAELQNGFVKLTNENMEVTSALQSEQHVKKELAKKLGQLQENLGELKETLELKTQEARALQEQRDQYYGHLQQYTVAYQQLAAEREELQKQYLLQTQLMDRLQHEEVQGKVTVEMHLKELQQTKESLEAVAKENKELQAQISQLAAELDGRMLHRLDGDGVESEVMSEEMKNPSFVIPEKFESHEEMVTFLTSAMSQVEKEREEMRQQLAVQKQQCRNLLQQIAALRQEQQHNITLSEDSTMDSVPVEVHEALKTAMEKLQSRFTDLIQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQSQRAILKQRHQEKEEYISRLAQDKEEMKIKLLELQDLVMRLVKERNEWYSKYVAAAQSPELLASQNEKALPVERRIELNATDGEGLREVNLADEAEQDAAALHQSSFYPTDTKAAQPSQEDPTAKQIMQLLREIQNPQERSGSLLENPCIPFFYRADENDEVKIMVV", "length": 981, "header": "tr|A0A8V1ACC7-1|A0A8V1ACC7_CHICK Computationally mapped isoform of Golgin A2 OS=Gallus gallus OX=9031 GN=GOLGA2 PE=1 SV=1 CANONICAL=A0A8V1AJE2-1" }, "locus": { "chromosome": "17", "start_pos": 5688011, "end_pos": 5671436, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068133.1", "url": "https://www.ensembl.org/id/ENSGALT00010068133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041876.1", "url": "https://www.ensembl.org/id/ENSGALP00010041876.1" } ] } }, { "isoform_ac": "A0A8V1ACD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2/entry#A0A8V1ACD2-1", "sequence": { "sequence": "MADGSRQSKLAAAKKKLKEYQQKNSPGATAGAKKKRKAKEGSRPETPTNDDRQSPENAYFDSDVATRNADQLAADVPVLSNSNSLPSCASVLPAPGSTQLTQIHEAEDRKNTLDENRSLSSTESLRQLSEQLNGLVAQSTSYVNGESGVSSTNIKEMETRYQELAVALDSSNLTNKQLITKIEELKQQNQEAVNQLEKEKKEFEQKFSKEQAALREQLQVHIQTIGILVSEKSELQTALGHTQQAARQKSGEAEDLAARLQSSRQRVSELERTLSSISMQQKQSEKHNKELVKERDNLKLELYKQSKGSEEIKQQNSELSEKLRSVVSENSAMKLDVEDLHKKLEMAELMIQQFSNHTGNVDANQQLQMALEERASLETQITQLSESLHQLRAERDQYVEKLKEEGSIWQQRVQQLSEQVRTMAEEKEKHVAQIQELESNVTELLSKSAVKPMDVEPSLPAGPTAAELSLQEEIKRLQHEKEELHGQYQAQVRDNEQLSHLNQEQEERLLELEKTVQRYNEESVDRQQILESMQSDKATISRALSQNRELKEQLAELQNGFVKLTNENMEVTSALQSEQHVKKELAKKLGQLQENLGELKETLELKTQEARALQEQRDQYYGHLQQYTVAYQQLAAEREELQKQYLLQTQLMDRLQHEEVQGKVTVEMHLKELQQTKESLEAVAKENKELQAQISQLAAELDGRMLHRLDGDGVESEVMSEEMKNPSFVIPEKFESHEEMVTFLTSAMSQVEKEREEMRQQLAVQKQQCRNLLQQIAALRQEQQHNITLSEDSTMDSVPVEVHEALKTAMEKLQSRFTDLIQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQSQRAILKQRHQEKEEYISRLAQDKEEMKIKLLELQDLVMRLVKERNEWYSKYVAAAQSPELLASQNEKALPVERRIELNATDGEGLREVNLADEAEQDAAALHQSSFYPTDTKAAQPSQEDPTAKQIMQLLREIQNPQERSGSLLENPCIPFFYRADENDEVKIMVV", "length": 1023, "header": "tr|A0A8V1ACD2-1|A0A8V1ACD2_CHICK Computationally mapped isoform of Golgin A2 OS=Gallus gallus OX=9031 GN=GOLGA2 PE=1 SV=1 CANONICAL=A0A8V1AJE2-1" }, "locus": { "chromosome": "17", "start_pos": 5688011, "end_pos": 5670378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068138.1", "url": "https://www.ensembl.org/id/ENSGALT00010068138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041881.1", "url": "https://www.ensembl.org/id/ENSGALP00010041881.1" } ] } }, { "isoform_ac": "A0A8V1AF58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2/entry#A0A8V1AF58-1", "sequence": { "sequence": "MADGSRQSKLAAAKKKLKEYQQKNSPGATAGAKKKRKAKEGSRPETPTNDDRQSPENIQNILKVLVSDLNRSNGVAIPSLDKRKAYFDSDVATRNADQLAADVPVLSNSNSLPSCASVLPAPGSTQLTQIHEAEDRKNTLDENRSLSSTESLRQLSEQLNGLVAQSTSYVNGESGVSSTNIKEMEKQQNQEAVNQLEKEKKEFEQKFSKEQAALREQLQVHIQTIGILVSEKSELQTALGHTQQAARQKSGEAEDLAARLQSSRQRVSELERTLSSISMQQKQSEKHNKELVKERDNLKLELYKQSKGSEEIKQQNSELSEKLRSVVSENSAMKLDVEDLHKKLEMAELMIQQFSNHTGNVDANQQLQMALEERASLETQITQLSESLHQLRAERDQYVEKLKEEGSIWQQRVQQLSEQVRTMAEEKEKHVAQIQELESNVTELLSKSAVKPMDVEPSLPAGPTAAELSLQEEIKRLQHEKEELHGQYQAQVRDNEQLSHLNQEQEERLLELEKTVQRYNEESVDRQQILESMQSDKATISRALSQNRELKEQLAELQNGFVKLTNENMEVTSALQSEQHVKKELAKKLGQLQENLGELKETLELKTQEARALQEQRDQYYGHLQQYTVAYQQLAAEREELQKQYLLQTQLMDRLQHEEVQGKVTVEMHLKELQQTKESLEAVAKENKELQAQISQLAAELDGRMLHRLDGDGVESEVMSEEMKNPSFVIPEKFESHEEMVTFLTSAMSQVEKEREEMRQQLAVQKQQCRNLLQQIAALRQEQQHNITLSEDSTMDSVPVEVHEALKTAMEKLQSRFTDLIQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQSQRAILKQRHQEKEEYISRLAQDKEEMKIKLLELQDLVMRLVKERNEWYSKYVAAAQSPELLASQNEKALPVERRIELNATDGEGLREVNLADEAEQDAAALHQSSFYPTDTKAAQPSQEDPTAKQIMQLLREIQNPQERSGSLLENPCIPFFYRADENDEVKIMVV", "length": 1023, "header": "tr|A0A8V1AF58-1|A0A8V1AF58_CHICK Computationally mapped isoform of Golgin A2 OS=Gallus gallus OX=9031 GN=GOLGA2 PE=1 SV=1 CANONICAL=A0A8V1AJE2-1" }, "locus": { "chromosome": "17", "start_pos": 5688011, "end_pos": 5670378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068135.1", "url": "https://www.ensembl.org/id/ENSGALT00010068135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041878.1", "url": "https://www.ensembl.org/id/ENSGALP00010041878.1" } ] } }, { "isoform_ac": "A0A8V1AF62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2/entry#A0A8V1AF62-1", "sequence": { "sequence": 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"header": "tr|A0A8V1AF62-1|A0A8V1AF62_CHICK Computationally mapped isoform of Golgin A2 OS=Gallus gallus OX=9031 GN=GOLGA2 PE=1 SV=1 CANONICAL=A0A8V1AJE2-1" }, "locus": { "chromosome": "17", "start_pos": 5688011, "end_pos": 5670378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068140.1", "url": "https://www.ensembl.org/id/ENSGALT00010068140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041883.1", "url": "https://www.ensembl.org/id/ENSGALP00010041883.1" } ] } }, { "isoform_ac": "A0A8V1AJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2/entry#A0A8V1AJE2-1", "sequence": { "sequence": "MADGSRQSKLAAAKKKLKEYQQKNSPGATAGAKKKRKAKEGSRPETPTNDDRQSPENIQNILKVLVSDLNRSNGVAIPSLDKRKAYFDSDVATRNADQLAADVPVLSNSNSLPSCASVLPAPGSTQLTQIHEAEDRKNTLDENRSLSSTESLRQLSEQLNGLVAQSTSYVNGESGVSSTNIKEMETRYQELAVALDSSNLTNKQLITKIEELKQQNQEAVNQLEKEKKEFEQKFSKEQAALREQLQVHIQTIGILVSEKSELQTALGHTQQAARQKSGEAEDLAARLQSSRQRVSELERTLSSISMQQKQSEKHNKELVKERDNLKLELYKQSKGSEEIKQQNSELSEKLRSVVSENSAMKLDVEDLHKKLEMAELMIQQFSNHTGNVDANQQLQMALEERASLETQITQLSESLHQLRAERDQYVEKLKEEGSIWQQRVQQLSEQVRTMAEEKEKHVAQIQELESNVTELLSKSAVKPMDVEPSLPAGPTAAELSLQEEIKRLQHEKEELHGQYQAQVRDNEQLSHLNQEQEERLLELEKTVQRYNEESVDRQQILESMQSDKATISRALSQNRELKEQLAELQNGFVKLTNENMEVTSALQSEQHVKKELAKKLGQLQENLGELKETLELKTQEARALQEQRDQYYGHLQQYTVAYQQLAAEREELQKQYLLQTQLMDRLQHEEVQGKVTVEMHLKELQQTKESLEAVAKENKELQAQISQLAAELDGRMLHRLDGDGVESEVMSEEMKNPSFVIPEKFESHEEMVTFLTSAMSQVEKEREEMRQQLAVQKQQCRNLLQQIAALRQEQQHNITLSEDSTMDSVPVEVHEALKTAMEKLQSRFTDLIQEKADLKERLEELEHRCIQLSGETDTIGEYIALYQSQRAILKQRHQEKEEYISRLAQDKEEMKIKLLELQDLVMRLVKERNEWYSKYVAAAQSPELLASQNEKALPVERRIELNATDGEGLREVNLADEAEQDAAALHQSSFYPTDTKAAQPSQEDPTAKQIMQLLREIQNPQERSGSLLENPCIPFFYRADENDEVKIMVV", "length": 1050, "header": "tr|A0A8V1AJE2-1|A0A8V1AJE2_CHICK Isoform 1 of Golgin A2 OS=Gallus gallus OX=9031 GN=GOLGA2 PE=1 SV=1 CANONICAL=A0A8V1AJE2-1" }, "locus": { "chromosome": "17", "start_pos": 5688011, "end_pos": 5670378, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068137.1", "url": "https://www.ensembl.org/id/ENSGALT00010068137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041880.1", "url": "https://www.ensembl.org/id/ENSGALP00010041880.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 491, "start_aa": "Thr", "end_pos": 491, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr491", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-162658", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162658", "resource": "Reactome", "description": "Golgi Cisternae Pericentriolar Stack Reorganization" }, { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2" } ], "pmid": "" }, { "name": "Golgi cis cisterna", "id": "GO:0000137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000137", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJE2" }, { "id": "PF15070", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Golgin subfamily A conserved", "eco_id": "ECO_0000259", "start_pos": 410, "end_pos": 940, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 491 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 962, "end_pos": 964 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { 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"site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJG2-1", "uniprot_ac": "A0A8V1AJG2", "uniprot_id": "A0A8V1AJG2_CHICK", "mass": { "chemical_mass": 35594.0, "monoisotopic_mass": 35594.0 }, "refseq": { "ac": "XP_046758526", "name": "alpha-ketoglutarate-dependent dioxygenase alkB homolog 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758526" }, "gene_names": [ { "name": "ALKBH4", "type": "recommended", "evidence": [ { "id": "A0A8V1AJG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ] }, { "name": "ALKBH4", "type": "synonym", "evidence": [ { "id": "XP_046758526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758526" } ] } ], "protein_names": [ { "name": "AlkB homolog 4, lysine demethylase", "type": "synonym", "evidence": [ { "id": "A0A8V1AJG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2/entry#names_and_taxonomy" } ] }, { "name": "alpha-ketoglutarate-dependent dioxygenase alkB homolog 4", "type": "synonym", "evidence": [ { "id": "XP_046758526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758526" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758526" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALKBH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2", "locus": { "chromosome": "19", "start_pos": 4638058, "end_pos": 4641101, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029309", "url": "https://www.ensembl.org/id/ENSGALG00010029309" } ] } } ], "crossref": [ { "id": "A0A8V1AJG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "417510", "url": "https://www.ncbi.nlm.nih.gov/gene/417510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MNTLRPC", "url": "https://omabrowser.org/oma/group/MNTLRPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJG2", "url": "https://www.orthodb.org/?gene=A0A8V1AJG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12463", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12463", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12463:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12463:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_046758526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758526", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AC46", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLELLGRKPRAQTQPGRERAVLNIPHSARSRAGSFHMEGDDNFTYCPSTGLAEGNEHTPFAGWAFPFPGVFLAEEFVSEEEEAEMVELMDRDEWKPSQSGRKKQDYGPKVNFKKQRLKAGGFTGLPSFSKKIVAQMEACSVLGGFLPVEQCNLDYRPERGSAIDPHFDDWWLWGERLVSLNLLSKTVLSMSCDSEDTIQLFPTFGNENGELNPRASLTQTSACENSGKQGSSCLLSPRLVPSKEVTVAIHLPRRSLVVLYGDARYKWKHAIYRRHIEHRRVCVTFRELSAEFSAGGRREELGKELLEIALSFQGAPV", "length": 317, "header": "tr|A0A8V1AJG2-1|A0A8V1AJG2_CHICK Isoform 1 of AlkB homolog 4, lysine demethylase OS=Gallus gallus OX=9031 GN=ALKBH4 PE=4 SV=1 CANONICAL=A0A8V1AJG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2/entry#A0A8V1AC46-1", "sequence": { "sequence": "MDSPLTASVFPHTWGDDNFTYCPSTGLAEGNEHTPFAGWAFPFPGVFLAEEFVSEEEEAEMVELMDRDEWKPSQSGRKKQDYGPKVNFKKQRLKAGGFTGLPSFSKKIVAQMEACSVLGGFLPVEQCNLDYRPERGSAIDPHFDDWWLWGERLVSLNLLSKTVLSMSCDSEDTIQLFPTFGNENGELNPRASLTQTSACENSGKQGSSCLLSPRLVPSKEVTVAIHLPRRSLVVLYGDARYKWKHAIYRRHIEHRRVCVTFRELSAEFSAGGRREELGKELLEIALSFQGAPV", "length": 293, "header": "tr|A0A8V1AC46-1|A0A8V1AC46_CHICK Computationally mapped isoform of AlkB homolog 4, lysine demethylase OS=Gallus gallus OX=9031 GN=ALKBH4 PE=4 SV=1 CANONICAL=A0A8V1AJG2-1" }, "locus": { "chromosome": "19", "start_pos": 4640902, "end_pos": 4638126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070880.1", "url": "https://www.ensembl.org/id/ENSGALT00010070880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043571.1", "url": "https://www.ensembl.org/id/ENSGALP00010043571.1" } ] } }, { "isoform_ac": "A0A8V1AJG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2/entry#A0A8V1AJG2-1", "sequence": { "sequence": "MLELLGRKPRAQTQPGRERAVLNIPHSARSRAGSFHMEGDDNFTYCPSTGLAEGNEHTPFAGWAFPFPGVFLAEEFVSEEEEAEMVELMDRDEWKPSQSGRKKQDYGPKVNFKKQRLKAGGFTGLPSFSKKIVAQMEACSVLGGFLPVEQCNLDYRPERGSAIDPHFDDWWLWGERLVSLNLLSKTVLSMSCDSEDTIQLFPTFGNENGELNPRASLTQTSACENSGKQGSSCLLSPRLVPSKEVTVAIHLPRRSLVVLYGDARYKWKHAIYRRHIEHRRVCVTFRELSAEFSAGGRREELGKELLEIALSFQGAPV", "length": 317, "header": "tr|A0A8V1AJG2-1|A0A8V1AJG2_CHICK Isoform 1 of AlkB homolog 4, lysine demethylase OS=Gallus gallus OX=9031 GN=ALKBH4 PE=4 SV=1 CANONICAL=A0A8V1AJG2-1" }, "locus": { "chromosome": "19", "start_pos": 4639755, "end_pos": 4638126, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070879.1", "url": "https://www.ensembl.org/id/ENSGALT00010070879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043570.1", "url": "https://www.ensembl.org/id/ENSGALP00010043570.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MV12-1", "protein_name": "AlkB homolog 4, lysine demethylase", "gene_name": "ALKBH4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARRRRPRVPKPQHGNPMLAPALASVQEVAPRESVRGGDHRKEASPRTSRPAHGLPLPAAPAAPPLRPGRRDAAMAAAAVAPPEVLRECGCKGIRTCLICERQRGGDPPWQHPSQRTHRFIYYPDTGWAVGAEESDFEGWAFPFPGVTLIEDFVTPEEEAEMVQLMDRDPWKLSQSGRRKQDYGPKVNFRKQKLKRAGFRGLPSFSREVVRRMGLYPILEDFRPVEQCNLDYSPERGSAIDPHLDDAWLWGERLVSLNLLSPTVLSMSREAPGSLLLCLAPSGFPEALADSAMAPSRSVPCQEVEVAVPLPRRSLVVLRGGARHQWKHAIHRRHIGARRVGVTFRELSAEFGPGGKQQELGRELLQMALSFQGRPTT", "length": 377 }, "evidence": [ { "id": "A0A8V1AJG2", "url": "https://omabrowser.org/oma/group/A0A8V1AJG2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RKF4-1", "protein_name": "AlkB homolog 4, lysine demethylase", "gene_name": "ALKBH4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAAVAAPEVLRECGCKGIRTCLICERQRGGDPPWQHSPQKTHRFIYYTDTGWAVGAEESDFEGWAFPFPGVTLIEDFVTREEEAEMVQLMDRDPWKLSQSGRRKQDYGPKVNFRKQKLKTASFRGLPSFSREVVRRMGLYPVLEDFRPVEQCNLDYCPERGSAIDPHLDDAWLWGERLVSLNLLSPTVLSMSREAPGSLLLCLAPSGFPEALVEGAVAPSRSVLCQEVEVAVPLPRRSLLVLTGAARHQWKHAIHRRHIEARRVSATFRELSADFGPGGRQQDLGRELLQISLSFQGRPT", "length": 302 }, "evidence": [ { "id": "A0A8V1AJG2", "url": "https://omabrowser.org/oma/group/A0A8V1AJG2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D8F1-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4", "gene_name": "Alkbh4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAEVSLLQECGCKGIRTCLICERQRHRDPPWQICLQKKCCFLYCPDTGWAAGAEGSDLEGWAFPFPGVTLIQDFVTPEEEAEMVRLMDCDPWKLSQSGRKKQDYGPKVNFRKQKLKMAGFQGLPGFSQKVVQRMGLYPGLEDFQPVEQCNLDYSPERGSAIDPHLDDAWLWGERLVSLNLLSATVVSMSPEAPGSLLLCSAPSVRPDAFEDSLVAPSRSVPCQEVEVAITVPRRSLLVLTGAARHQWTHAIHRRHIKARRVCATFRELSSEFLPGGKQQELGQELLQAALSFQGRPV", "length": 300 }, "evidence": [ { "id": "A0A8V1AJG2", "url": "https://omabrowser.org/oma/group/A0A8V1AJG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXW9-1", "protein_name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4", "gene_name": "ALKBH4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAETPEVLRECGCKGIRTCLICERQRGSDPPWELPPAKTYRFIYCSDTGWAVGTEESDFEGWAFPFPGVMLIEDFVTREEEAELVRLMDRDPWKLSQSGRRKQDYGPKVNFRKQKLKTEGFCGLPSFSREVVRRMGLYPGLEGFRPVEQCNLDYCPERGSAIDPHLDDAWLWGERLVSLNLLSPTVLSMCREAPGSLLLCSAPSAAPEALVDSVIAPSRSVLCQEVEVAIPLPARSLLVLTGAARHQWKHAIHRRHIEARRVCVTFRELSAEFGPGGRQQELGQELLRIALSFQGRPV", "length": 302 }, "evidence": [ { "id": "A0A8V1AJG2", "url": "https://omabrowser.org/oma/group/A0A8V1AJG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" }, { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" }, { "name": "demethylase activity", "id": "GO:0032451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" }, { "name": "broad specificity oxidative DNA demethylase activity", "id": "GO:0035516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" }, { "name": "cleavage furrow ingression", "id": "GO:0036090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" }, { "name": "demethylation", "id": "GO:0070988", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070988", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" }, { "name": "positive regulation of gene expression, epigenetic", "id": "GO:0141137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141137", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" }, { "name": "contractile ring", "id": "GO:0070938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJG8-1", "uniprot_ac": "A0A8V1AJG8", "uniprot_id": "A0A8V1AJG8_CHICK", "mass": { "chemical_mass": 82917.0, "monoisotopic_mass": 82917.0 }, "refseq": {}, "gene_names": [ { "name": "TMEM161A", "type": "recommended", "evidence": [ { "id": "A0A8V1AJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8" } ] } ], "protein_names": [ { "name": "Transmembrane protein 161A", "type": "recommended", "evidence": [ { "id": "A0A8V1AJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM161A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8", "locus": { "chromosome": "28", "start_pos": 4080977, "end_pos": 4076004, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028131", "url": "https://www.ensembl.org/id/ENSGALG00010028131" } ] } } ], "crossref": [ { "id": "A0A8V1AJG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7J3", "url": "https://www.orthodb.org/?gene=A0A8V1A7J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF88", "url": "https://www.orthodb.org/?gene=A0A8V1AF88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJG8", "url": "https://www.orthodb.org/?gene=A0A8V1AJG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13624:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13624:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10268", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10268", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPGHRPRPDRGHRQRQGLPPLGWAGGHSEVRAVSAKCFRAPCWARVAPECQEQCAVLFAMHGAVCNARCCLQCTVLFAMHGAACNARCCLQCAVLFAMHAAFAAHGAMHAAQTLPLPSDSAALALPTLSPPVSQGSNGIKRIDCIKRETRAEGAAAPRAVHASALRARQPWGCTGIAKPPFVHTCSTPGARTRHTRARCTHAHALRRAARAVDEPQLPGGSARGTDRRQRARPPRGSASPLAKELPISRKTASDWPAGRGGGGRASCGRLCADPGMAVMGVQVVVSLLAASVMQKLAPHCSFARWLLCNGSLHRYKHPSEEELRVLAGKQRPKTKRDRRMNGVTDDKPLSVPRDIDLHLDTSPITAVDALVLRYFLEYQWFVDFAVYATAVYIFTEGYSCVVEPQREMNLGVLWCLLTVFFSIKVFFMVMRHYFRSEEGGERSVCLTFAFFFLLLAMVVLVVREEYLEFGLEPGLDSVSSNLESILKPRGWEWTLPLARLAFKLGLVALCSFLGACLTFPGLRLAQTHLDALRMAADRPLAQVLLHVSFLAPVLLVVMWIRPISRDFVLHAPMGKQTVQILSDSAFNTARLWAVVGLCGLRLAATRPHLQAYLGLAERWVQQMRKEAGRIAAVEIQRKITRIYCYVPVVSLQYLGPIILTLHCALLLKTLGHHSWGLYPESPPVPAAVAAAPSRPGGEDGEEVRAAVEQITGVLGGILTPLFFRGLFAFLTWWVAACQVVTSLFGLYFHQHLAAS", "length": 757, "header": "tr|A0A8V1AJG8-1|A0A8V1AJG8_CHICK Isoform 1 of Transmembrane protein 161A OS=Gallus gallus OX=9031 GN=TMEM161A PE=3 SV=1 CANONICAL=A0A8V1AJG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8/entry#A0A8V1A7J3-1", "sequence": { "sequence": "MAVMGVQVVVSLLAASVMQKLAPHCSFARWLLCNGRRMNGVTDDKPLSVPRDIDLHLDTSPITAVDALVLRYFLEYQWFVDFAVYATAVYIFTEGYSCVVEPQREMNLGVLWCLLTVFFSIKVFFMVMRHYFRSEEGGERSVCLTFAFFFLLLAMVVLVVREEYLEFGLEPGLDSVSSNLESILKPRGWEWTLPLARLAFKLGLVALCSFLGACLTFPGLRLAQTHLDALRMAADRPLAQVLLHVSFLAPVLLVVMWIRPISRDFVLHAPMGKQTVQILSDSAFNTARLWAVVGLCGLRLAATRPHLQAYLGLAERWVQQMRKEAGRIAAVEIQRKITRIYCYVPVVSLQYLGPIILTLHCALLLKTLGHHSWGLYPESPPVPAAVAAAPSRPGGEDGEEVRAAVEQITGVLGGILTPLFFRGLFAFLTWWVAACQVVTSLFGLYFHQHLAAS", "length": 453, "header": "tr|A0A8V1A7J3-1|A0A8V1A7J3_CHICK Computationally mapped isoform of Transmembrane protein 161A OS=Gallus gallus OX=9031 GN=TMEM161A PE=3 SV=1 CANONICAL=A0A8V1AJG8-1" }, "locus": { "chromosome": "28", "start_pos": 4080387, "end_pos": 4077004, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068171.1", "url": "https://www.ensembl.org/id/ENSGALT00010068171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041914.1", "url": "https://www.ensembl.org/id/ENSGALP00010041914.1" } ] } }, { "isoform_ac": "A0A8V1AF88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8/entry#A0A8V1AF88-1", "sequence": { "sequence": "MGVQVVVSLLAASVMQKLAPHCSFARWLLCNGSLHRYKHPSEEELRVLAGKQRPKTKRDRRMNGVTDDKPLSVPRDIDLHLDTSPITAVDALVLRYFLEYQWFVDFAVYATAVYIFTEGYSCVVEPQREMNLGVLWCLLTVFFSIKVFFMVMRHYFRSEEGGERSVCLTFAFFFLLLAMVVLVVREEYLEFGLEPGLDSVSSNLESILKPRGWEWTLPLARLAFKLGLVALCSFLGACLTFPGLRLAQTHLDALRMAADRPLAQVLLHVSFLAPVLLVVMWIRPISRDFVLHAPMGKQTVQILSDSAFNTARLWAVVGLCGLRLAATRPHLQAYLGLAERWVQQMRKEAGRIAAVEIQRKITRIYCYVPVVSLQYLGPIILTLHCALLLKTLGHHSWGLYPESPPVPAAVAAAPSRPGGEDGEEVRAAVEQITGVLGGILTPLFFRGLFAFLTCRLSAGRVLYIRVQQCVASPLLPPITAVPVPIAPAPCSDIAAPCSDIAAPQRGLLLCCRLQTAAQSSAASRDPSRDCRGAVGLGQQPRFLEQTLGFALRSLPPLTECVCFYRVSALPSGVRALGVVPLLGVKSLGPAASAVGCFRNK", "length": 600, "header": "tr|A0A8V1AF88-1|A0A8V1AF88_CHICK Computationally mapped isoform of Transmembrane protein 161A OS=Gallus gallus OX=9031 GN=TMEM161A PE=3 SV=1 CANONICAL=A0A8V1AJG8-1" }, "locus": { "chromosome": "28", "start_pos": 4080954, "end_pos": 4077484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068170.1", "url": "https://www.ensembl.org/id/ENSGALT00010068170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041913.1", "url": "https://www.ensembl.org/id/ENSGALP00010041913.1" } ] } }, { "isoform_ac": "A0A8V1AJG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8/entry#A0A8V1AJG8-1", "sequence": { "sequence": "MATPGHRPRPDRGHRQRQGLPPLGWAGGHSEVRAVSAKCFRAPCWARVAPECQEQCAVLFAMHGAVCNARCCLQCTVLFAMHGAACNARCCLQCAVLFAMHAAFAAHGAMHAAQTLPLPSDSAALALPTLSPPVSQGSNGIKRIDCIKRETRAEGAAAPRAVHASALRARQPWGCTGIAKPPFVHTCSTPGARTRHTRARCTHAHALRRAARAVDEPQLPGGSARGTDRRQRARPPRGSASPLAKELPISRKTASDWPAGRGGGGRASCGRLCADPGMAVMGVQVVVSLLAASVMQKLAPHCSFARWLLCNGSLHRYKHPSEEELRVLAGKQRPKTKRDRRMNGVTDDKPLSVPRDIDLHLDTSPITAVDALVLRYFLEYQWFVDFAVYATAVYIFTEGYSCVVEPQREMNLGVLWCLLTVFFSIKVFFMVMRHYFRSEEGGERSVCLTFAFFFLLLAMVVLVVREEYLEFGLEPGLDSVSSNLESILKPRGWEWTLPLARLAFKLGLVALCSFLGACLTFPGLRLAQTHLDALRMAADRPLAQVLLHVSFLAPVLLVVMWIRPISRDFVLHAPMGKQTVQILSDSAFNTARLWAVVGLCGLRLAATRPHLQAYLGLAERWVQQMRKEAGRIAAVEIQRKITRIYCYVPVVSLQYLGPIILTLHCALLLKTLGHHSWGLYPESPPVPAAVAAAPSRPGGEDGEEVRAAVEQITGVLGGILTPLFFRGLFAFLTWWVAACQVVTSLFGLYFHQHLAAS", "length": 757, "header": "tr|A0A8V1AJG8-1|A0A8V1AJG8_CHICK Isoform 1 of Transmembrane protein 161A OS=Gallus gallus OX=9031 GN=TMEM161A PE=3 SV=1 CANONICAL=A0A8V1AJG8-1" }, "locus": { "chromosome": "28", "start_pos": 4080387, "end_pos": 4076173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068172.1", "url": "https://www.ensembl.org/id/ENSGALT00010068172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041915.1", "url": "https://www.ensembl.org/id/ENSGALP00010041915.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3, "start_aa": "Thr", "end_pos": 3, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJG8" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 111, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 3 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 311, "end_pos": 313 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJH1-1", "uniprot_ac": "A0A8V1AJH1", "uniprot_id": "A0A8V1AJH1_CHICK", "mass": { "chemical_mass": 21177.0, "monoisotopic_mass": 21177.0 }, "refseq": { "ac": "XP_015155269", "name": "uncharacterized protein C19orf71 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155269" }, "gene_names": [ { "name": "C19orf71", "type": "recommended", "evidence": [ { "id": "A0A8V1AJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH1" } ] }, { "name": "C19orf71", "type": "synonym", "evidence": [ { "id": "XP_015155269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155269" } ] } ], "protein_names": [ { "name": "Tektin bundle interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C19orf71 homolog", "type": "synonym", "evidence": [ { "id": "XP_015155269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155269" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155269.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155269" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C19orf71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJH1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "101749669", "url": "https://www.ncbi.nlm.nih.gov/gene/101749669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749669", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749669", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EAWYNLP", "url": "https://omabrowser.org/oma/group/EAWYNLP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJH1", "url": "https://www.orthodb.org/?gene=A0A8V1AJH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31254:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31254:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015155269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155269", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGVRRAWVPQSTLEAEFPLPLCSEQYVTLRGPRCAPVLRQAVRWKMAPLGRDAVGQSWWTEPSCHGAEDTQYSLTHSTAWQRWQRSQSAPERQPLPPVYDQHLREAACWDPTVPAAYPGPGTRWGAFLWQERPILGKEYVATRSQSTAAQGGSPGYVPLLSFCRPPTTRRDVCSWSLLQHQPSAPQ", "length": 188, "header": "tr|A0A8V1AJH1-1|A0A8V1AJH1_CHICK Isoform 1 of Tektin bundle interacting protein 1 OS=Gallus gallus OX=9031 GN=C19orf71 PE=4 SV=1 CANONICAL=A0A8V1AJH1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH1/entry#A0A8V1AJH1-1", "sequence": { "sequence": "MEPGVRRAWVPQSTLEAEFPLPLCSEQYVTLRGPRCAPVLRQAVRWKMAPLGRDAVGQSWWTEPSCHGAEDTQYSLTHSTAWQRWQRSQSAPERQPLPPVYDQHLREAACWDPTVPAAYPGPGTRWGAFLWQERPILGKEYVATRSQSTAAQGGSPGYVPLLSFCRPPTTRRDVCSWSLLQHQPSAPQ", "length": 188, "header": "tr|A0A8V1AJH1-1|A0A8V1AJH1_CHICK Isoform 1 of Tektin bundle interacting protein 1 OS=Gallus gallus OX=9031 GN=C19orf71 PE=4 SV=1 CANONICAL=A0A8V1AJH1-1" }, "locus": { "chromosome": "28", "start_pos": 1484998, "end_pos": 1484081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068177.1", "url": "https://www.ensembl.org/id/ENSGALT00010068177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041920.1", "url": "https://www.ensembl.org/id/ENSGALP00010041920.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101749669", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749669", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VRW9-1", "protein_name": "Tektin bundle interacting protein 1", "gene_name": "TEKTIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQTLRRKAAQPYVPRDTLEVDFPASLYSDDYLSQEGPRWTPAIKQATRWKYTPMGRDAAGQLWYTGLTNSDSREAWYTVPRALDSPYREAYARWHGCYRHREQSMPSAYAQRLWETAWYDPIIPAQYRDPSTRWGSMLWKDRPIRGKEYVINRHRFGVEPLWRASDYVPYLSAPQHPRYTAQNYRQWDLEPYCPSTNQRPPPNYTPIHG", "length": 209 }, "evidence": [ { "id": "A0A8V1AJH1", "url": "https://omabrowser.org/oma/group/A0A8V1AJH1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6H6Q4-1", "protein_name": "Tektin bundle-interacting protein 1", "gene_name": "Tektip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENVRREATRPSVPSGTLELYFPDHLYRNDYVSLEGPRWAPAIKQAVRWKFTPMGRDAAGQVWFTGLTNSEPGDAWYKLPRALDTPYREAHTRWHGCFQSRQRGLPPAYTQHLREMAFWDPAITAQYLNSGPRWGCMQWRDRQIRGKEFVVTRNQFGAKLPWRSDYVPLLSLPQRPRFTAQDFRQRGLQRPCPAIGQPPPAFTPAL", "length": 206 }, "evidence": [ { "id": "A0A8V1AJH1", "url": "https://omabrowser.org/oma/group/A0A8V1AJH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A6NCJ1-1", "protein_name": "Tektin bundle-interacting protein 1", "gene_name": "TEKTIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQTLRQEAARPCIPSGTLEASFPAPLYSDDYLSLEGSRWPPAIRQATRWKYTPMGRDAAGQLWYTGLTNSDAWEAWYNLPRAPASPFREAYNRWHSCYQHRECSMPSAYTQHLRETAWHDPIVPAQYQAPSTRWGSALWKDRPIRGKEYVLNRNRYGVEPLWRASDYVPSLSAPQRPPGTTQNYREWVLEPYCPSTCQRSPPSLTPTPR", "length": 209 }, "evidence": [ { "id": "A0A8V1AJH1", "url": "https://omabrowser.org/oma/group/A0A8V1AJH1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A8Z4-1", "protein_name": "Tektin bundle interacting protein 1", "gene_name": "Tektip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJI2-1", "uniprot_ac": "A0A8V1AJI2", "uniprot_id": "A0A8V1AJI2_CHICK", "mass": { "chemical_mass": 37357.0, "monoisotopic_mass": 37357.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Tyrosine-protein phosphatase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AJI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI2/entry#names_and_taxonomy" } ] } ], 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"https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46659", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46659", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46659:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46659:SF1", "database": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJI4-1", "uniprot_ac": "A0A8V1AJI4", "uniprot_id": "A0A8V1AJI4_CHICK", "mass": { "chemical_mass": 46062.0, "monoisotopic_mass": 46062.0 }, "refseq": {}, "gene_names": [ { "name": "C17orf58", "type": "recommended", "evidence": [ { "id": "A0A8V1AJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4" } ] } ], "protein_names": [ { "name": "Chromosome 17 open reading frame 58", "type": "synonym", "evidence": [ { "id": "A0A8V1AJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C17orf58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4", "locus": { "chromosome": "18", "start_pos": 7627170, "end_pos": 7619904, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029318", "url": "https://www.ensembl.org/id/ENSGALG00010029318" } ] } } ], "crossref": [ { "id": "A0A8V1AJI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03576", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417421", "url": "https://www.ncbi.nlm.nih.gov/gene/417421", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417421", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417421", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNRQETW", "url": "https://omabrowser.org/oma/group/VNRQETW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJI4", "url": "https://www.orthodb.org/?gene=A0A8V1AJI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALK7", "url": "https://www.orthodb.org/?gene=A0A8V1ALK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35967", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35967", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35967:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35967:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "FRTPHFWSLREACSEPLSRSSSGCGALPAGVPSAVPLPPPLGSGGTAVRCAERSPLQCAGSLPCAEKASQSVSKYVCNSADATPGQAKLPAWATTREDPSEHRLLSPTNLQHPKPPEISSLSSDKKKQTKPSTENSTGLRKHLLQYGGTLPLEPATEGPSPTSFDLNQANRKQADRRLAEAANSVSAHFQHAASSYHKITSLLGAHPFLDSGTAESADPNMLDHFNRPGKINPYKSVELLKMISKPSWVTNRQPPSLPYHFSMLKKGADMEKACLTECRKERDEVEAYCTSEFAVNGIVYNMERLGSGVHLITLLVNSDGLYKMSRLYITPDGFFFRVHILVVDSFNCSKPCPDFKLGSRYIVMGQIYHKRRQIPANLVQFLRGHLRPGDGLLASSSSYVKRFNRKRNRKVQGARTKCT", "length": 419, "header": "tr|A0A8V1AJI4-1|A0A8V1AJI4_CHICK Isoform 1 of Chromosome 17 open reading frame 58 OS=Gallus gallus OX=9031 GN=C17orf58 PE=4 SV=1 CANONICAL=A0A8V1AJI4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4/entry#A0A8V1AJI4-1", "sequence": { "sequence": "FRTPHFWSLREACSEPLSRSSSGCGALPAGVPSAVPLPPPLGSGGTAVRCAERSPLQCAGSLPCAEKASQSVSKYVCNSADATPGQAKLPAWATTREDPSEHRLLSPTNLQHPKPPEISSLSSDKKKQTKPSTENSTGLRKHLLQYGGTLPLEPATEGPSPTSFDLNQANRKQADRRLAEAANSVSAHFQHAASSYHKITSLLGAHPFLDSGTAESADPNMLDHFNRPGKINPYKSVELLKMISKPSWVTNRQPPSLPYHFSMLKKGADMEKACLTECRKERDEVEAYCTSEFAVNGIVYNMERLGSGVHLITLLVNSDGLYKMSRLYITPDGFFFRVHILVVDSFNCSKPCPDFKLGSRYIVMGQIYHKRRQIPANLVQFLRGHLRPGDGLLASSSSYVKRFNRKRNRKVQGARTKCT", "length": 419, "header": "tr|A0A8V1AJI4-1|A0A8V1AJI4_CHICK Isoform 1 of Chromosome 17 open reading frame 58 OS=Gallus gallus OX=9031 GN=C17orf58 PE=4 SV=1 CANONICAL=A0A8V1AJI4-1" }, "locus": { "chromosome": "18", "start_pos": 7626199, "end_pos": 7620103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070904.1", "url": "https://www.ensembl.org/id/ENSGALT00010070904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043595.1", "url": "https://www.ensembl.org/id/ENSGALP00010043595.1" } ] } }, { "isoform_ac": "A0A8V1ALK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4/entry#A0A8V1ALK7-1", "sequence": { "sequence": "MTTKALWLLCFIIRSSCSSAAGSLPCAEKASQSVSKYVCNSADATPGQAKLPAWATTREDPSEHRLLSPTNLQHPKPPEISSLSSDKKKQTKPSTENSTGLRKHLLQYGGTLPLEPATEGPSPTSFDLNQANRKQADRRLAEAANSVSAHFQHAASSYHKITSLLGAHPFLDSGTAESADPNMLDHFNRPGKINPYKSVELLKMISKPSWVTNRQPPSLPYHFSMLKKGADMEKACLTECRKERDEVEAYCTSEFAVNGIVYNMERLGSGVHLITLLVNSDGLYKMSRLYITPDGFFFRVHILVVDSFNCSKPCPDFKLGSRYIVMGQIYHKRRQIPANLVQFLRGHLRPGDGLLASSSSYVKRFNRKRNRKVQGARTKCT", "length": 381, "header": "tr|A0A8V1ALK7-1|A0A8V1ALK7_CHICK Computationally mapped isoform of Chromosome 17 open reading frame 58 OS=Gallus gallus OX=9031 GN=C17orf58 PE=4 SV=1 CANONICAL=A0A8V1AJI4-1" }, "locus": { "chromosome": "18", "start_pos": 7626199, "end_pos": 7621063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070903.1", "url": "https://www.ensembl.org/id/ENSGALT00010070903.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043594.1", "url": "https://www.ensembl.org/id/ENSGALP00010043594.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 83, "start_aa": "Thr", "end_pos": 83, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr83", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417421", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417421", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI4" }, { "id": "PS50189", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50189" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTR", "eco_id": "ECO_0000259", "start_pos": 274, "end_pos": 418, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 83 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 347, "end_pos": 349 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJK2-1", "uniprot_ac": "A0A8V1AJK2", "uniprot_id": "A0A8V1AJK2_CHICK", "mass": { "chemical_mass": 68481.0, "monoisotopic_mass": 68481.0 }, "refseq": {}, "gene_names": [ { "name": "NCBP3", "type": "recommended", "evidence": [ { "id": "A0A8V1AJK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ] } ], "protein_names": [ { "name": "Nuclear cap-binding protein subunit 3", "type": "recommended", "evidence": [ { "id": "A0A8V1AJK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2", "locus": { "chromosome": "19", "start_pos": 5631504, "end_pos": 5646737, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029326", "url": "https://www.ensembl.org/id/ENSGALG00010029326" } ] } } ], "crossref": [ { "id": "A0A8V1AJK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJK2", "url": "https://www.orthodb.org/?gene=A0A8V1AJK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16291:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16291:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10309", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10309", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVRGLRISVKAEATATTAEPRGPEPEPMEVEEGELETIPVRRSLRELIPDTSRRYENKAGSFITGIDEAIEKKEQRAKRFHFRAEVNLAQRNVALDRDMMKKAIPKVRLDTIYICGVDEMSTQDIFAYFKEYPPAHIEWLDDTSCNVVWLDEVTATRALINMSSFPDQEKPKGRENNEEKTAEKNKKEKQEESTDDETEEGEVEDENPSDIELDALTQVEEDSLLRNDLRPANKLAKGNKLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIHRDVIKKRTLIGDDVGLTPPYKHRHSGLVNVPEEPIEEEEEEEEVQDMDEDDRVVVEYRDDLQPFKQSRDRGAARRSSASASDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSIATSNVKNRIGSKGLSDKVVDVRLLLEEKRQNNNGLRQPNSIVKSDVRQRLGKRPHSPEVKPPSSISAPRREPISDVHSRLGIPKQDVKGLYSDTREKKSGNLWTRLGSAPKTQEKTSDKPENSVASPEEDDSELQRVWGALIKEKEESRQKKSRLDNLPSLQIEISRESSSGSDTES", "length": 600, "header": "tr|A0A8V1AJK2-1|A0A8V1AJK2_CHICK Isoform 1 of Nuclear cap-binding protein subunit 3 OS=Gallus gallus OX=9031 GN=NCBP3 PE=3 SV=1 CANONICAL=A0A8V1AJK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2/entry#A0A8V1AJK2-1", "sequence": { "sequence": "MAAVRGLRISVKAEATATTAEPRGPEPEPMEVEEGELETIPVRRSLRELIPDTSRRYENKAGSFITGIDEAIEKKEQRAKRFHFRAEVNLAQRNVALDRDMMKKAIPKVRLDTIYICGVDEMSTQDIFAYFKEYPPAHIEWLDDTSCNVVWLDEVTATRALINMSSFPDQEKPKGRENNEEKTAEKNKKEKQEESTDDETEEGEVEDENPSDIELDALTQVEEDSLLRNDLRPANKLAKGNKLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIHRDVIKKRTLIGDDVGLTPPYKHRHSGLVNVPEEPIEEEEEEEEVQDMDEDDRVVVEYRDDLQPFKQSRDRGAARRSSASASDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSIATSNVKNRIGSKGLSDKVVDVRLLLEEKRQNNNGLRQPNSIVKSDVRQRLGKRPHSPEVKPPSSISAPRREPISDVHSRLGIPKQDVKGLYSDTREKKSGNLWTRLGSAPKTQEKTSDKPENSVASPEEDDSELQRVWGALIKEKEESRQKKSRLDNLPSLQIEISRESSSGSDTES", "length": 600, "header": "tr|A0A8V1AJK2-1|A0A8V1AJK2_CHICK Isoform 1 of Nuclear cap-binding protein subunit 3 OS=Gallus gallus OX=9031 GN=NCBP3 PE=3 SV=1 CANONICAL=A0A8V1AJK2-1" }, "locus": { "chromosome": "19", "start_pos": 5646731, "end_pos": 5633443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070925.1", "url": "https://www.ensembl.org/id/ENSGALT00010070925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043616.1", "url": "https://www.ensembl.org/id/ENSGALP00010043616.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" }, { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" }, { "name": "RNA cap binding", "id": "GO:0000339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" }, { "name": "7-methylguanosine mRNA capping", "id": "GO:0006370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006370", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" }, { "name": "snRNA export from nucleus", "id": "GO:0006408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJK6-1", "uniprot_ac": "A0A8V1AJK6", "uniprot_id": "A0A8V1AJK6_CHICK", "mass": { "chemical_mass": 80181.0, "monoisotopic_mass": 80181.0 }, "refseq": {}, "gene_names": [ { "name": "CIZ1", "type": "recommended", "evidence": [ { "id": "A0A8V1AJK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6" } ] } ], "protein_names": [ { "name": "CDKN1A interacting zinc finger protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AJK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CIZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6", "locus": { "chromosome": "17", "start_pos": 5776565, "end_pos": 5756636, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028155", "url": "https://www.ensembl.org/id/ENSGALG00010028155" } ] } } ], "crossref": [ { "id": "A0A8V1AJK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A7N9", "url": "https://www.orthodb.org/?gene=A0A8V1A7N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACM3", "url": "https://www.orthodb.org/?gene=A0A8V1ACM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFD7", "url": "https://www.orthodb.org/?gene=A0A8V1AFD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJK6", "url": "https://www.orthodb.org/?gene=A0A8V1AJK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15491", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15491", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15491:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15491:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A7N9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A7N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFNQQQFQQHHHHPPAQQGGRGLPPPPPPPPQQQQMLSLRATNQPSLLNANPMLQRALLMQQMQGNLRGFNMTAPALQQFFPQATRHSLLGPPPVGVSLKPTRLGFPNLPFQRQNRMFRKDFQRVPDRKRELDAGSSSHMHGDEKIEFRGELRAGSEQNNSLSTEPRTPAEAVLNTEPAAKRLKSVTEESALENAAGSKEELSTHVQADGTNNVKQYAAESLSKERKFSEEPKAPEVLSSGGSLKVTIQQSSESRAISTTALKPGQWTCEMGTADASPESALKFYCYICKTNCCNQQNFQAHMAGIQHQQRLGEIQHMSNVCFVSLLPMVKEQKLLAEKDGETQQRWCNTCQIHFTGDLIKHRRTQEHKLAKRSLRPFCTVCSRHFKTPRKFVEHMKSPEHKQKAKEVRLGEKELGSPEDSEELITVDAVGCFEDDEEEEEEEEEEEGTGEGEDLDVVLVENEDSAAKQTGLKEVSLEDYKGSEKYCPDTAYGLDFLVPVAGYLCRLCHKFYHSDSAARLAHCKSLMHFENFQRYKVARHRATAAYPEAPLHSQGSGSQLLDDQKQPPATTEDSSKKTNANHGIDKEGTELSALQEQALRSPEGKGKLATAVAESKSLASVTDVCGITVVEESLQESKSTATCPLPEESSAAGELLGHAVYEEEEANAARQGEGTDYCQDPGSGGGLGQKEASNVGQEAAAEPSSLAKGEAASLTSAGCRRSSRRKPR", "length": 728, "header": "tr|A0A8V1AJK6-1|A0A8V1AJK6_CHICK Isoform 1 of CDKN1A interacting zinc finger protein 1 OS=Gallus gallus OX=9031 GN=CIZ1 PE=4 SV=1 CANONICAL=A0A8V1AJK6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A7N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6/entry#A0A8V1A7N9-1", "sequence": { "sequence": "MFNQQQFQQQLLQLQHLLQQQQHHHHPPAQQGGRGLPPPPPPPPQQQQMLSLRATNQPSLLNANPMLQRALLMQQMQGNLRGFNMTAPALQQFFPQATRHSLLGPPPVGVSLKPTRLGFPNLPFQRQNRMFRKDFQRVPDRKRELDAGSSSHMHGDEKIEFRGELRAGSEQNNSLSTEPRTPAEAVLNTEPAAKRLKSVTEESALENAAGSKEELSTHVQADGTNNVKQYAAESLSKERKFSEEPKAPEVLSSGGSLKVTIQQSSESRAISTTALKPGQWTCEMGTADASPESALKFYCYICKTNCCNQQNFQAHMAGIQHQQRLGEIQHMSNVCFVSLLPMVKEQKLLAEKDGETQQRWCNTCQIHFTGDLIKHRRTQEHKLAKRSLRPFCTVCSRHFKTPRKFVEHMKSPEHKQKAKEVRLGEKELGSPEDSEELITVDAVGCFEDDEEEEEEEEEEEGTGEGEDLDVVLVENEDSAAKQTGLKEVSLEDYKGSEKYCPDTAYGLDFLVPVAGYLCRLCHKFYHSDSAARLAHCKSLMHFENFQRYKVARHRATAAYPEAPLHSQGSGSQLLDDQKQPPATTEDSSKKTNANHGIDKEGTELSALQEQALRSPEGKGKLATAVAESKSTATCPLPEESSAAGELLGHAVYEEEAAAEPSSLAKGEAASLTSAGCRRSSRRKPR", "length": 685, "header": "tr|A0A8V1A7N9-1|A0A8V1A7N9_CHICK Computationally mapped isoform of CDKN1A interacting zinc finger protein 1 OS=Gallus gallus OX=9031 GN=CIZ1 PE=4 SV=1 CANONICAL=A0A8V1AJK6-1" }, "locus": { "chromosome": "17", "start_pos": 5775561, "end_pos": 5757061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068221.1", "url": "https://www.ensembl.org/id/ENSGALT00010068221.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041964.1", "url": "https://www.ensembl.org/id/ENSGALP00010041964.1" } ] } }, { "isoform_ac": "A0A8V1ACM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6/entry#A0A8V1ACM3-1", "sequence": { "sequence": "MFNQQQFQQQLLQLQHLLQQQQHHHHPPAQQGGRGLPPPPPPPPQQQQMLSLRATNQPSLLNANPMLQRALLMQQMQGNLRGFNMTAPALQQFFPQATRHSLLGPPPVGVSLKPTRLGFPNLPFQRQNRMFRKDFQRVPDRKRELDAGSSSHMHGDEKIEFRGELRAGSEQNNSLSTEPRTPAEAVLNTEPAAKRLKSVTEESALENAAGSKEELSTHVQADGTNNVKQYAAESLSKERKFSEEPKAPEVLSSGGSLKVTIQQSSESRAISTTALKPGQWTCEMGTADASPESALKFYCYICKTNCCNQQNFQAHMAGIQHQQRLGEIQHMSNVCFVSLLPMVKEQKLLAEKDGETQQRWCNTCQIHFTGDLIKHRRTQEHKLAKRSLRPFCTVCSRHFKTPRKFVEHMKSPEHKQKAKEVRLGEKELGSPEDSEELITVDAVGCFEDDEEEEEEEEEEEGTGEGEDLDVVLVENEDSAAKQTGLKEVSLEDYKGSEKYCPDTAYGLDFLVPVAGYLCRLCHKFYHSDSAARLAHCKSLMHFENFQRYKVARHRATAAYPEAPLHSQGSGSQLLDDQKQPPATTEDSSKKTNANHGIDKEGTELSALQEQALRSPEEESLQESKSTATCPLPEESSAAGELLGHAVYEEEEANAARQGEGTDYCQDPGSGGGLGQKEASNVGQEAAAEPSSLAKGEAASLTSAGCRRSSRRKPR", "length": 714, "header": "tr|A0A8V1ACM3-1|A0A8V1ACM3_CHICK Computationally mapped isoform of CDKN1A interacting zinc finger protein 1 OS=Gallus gallus OX=9031 GN=CIZ1 PE=4 SV=1 CANONICAL=A0A8V1AJK6-1" }, "locus": { "chromosome": "17", "start_pos": 5775561, "end_pos": 5757061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068223.1", "url": "https://www.ensembl.org/id/ENSGALT00010068223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041966.1", "url": "https://www.ensembl.org/id/ENSGALP00010041966.1" } ] } }, { "isoform_ac": "A0A8V1AFD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6/entry#A0A8V1AFD7-1", "sequence": { "sequence": "MMTCLARCGRCRFWKSGLPPPPPPPPQQQQMLSLRATNQPSLLNANPMLQRALLMQQMQGNLRGFNMTAPALQQFFPQATRHSLLGPPPVGVSLKPTRLGFPNLPFQRQNRMFRKDFQRVPDRKRELDAGSSSHMHGDEKIEFRGELRAGSEQNNSLSTEPRTPAEAVLNTEPAAKRLKSVTEESALENAAGSKEELSTHVQADGTNNVKQYAAESLSKERKFSEEPKAPEVLSSGGSLKVTIQQSSESRAISTTALKPGQWTCEMGTADASPESALKFYCYICKTNCCNQQNFQAHMAGIQHQQRLGEIQHMSNVCFVSLLPMVKEQKLLAEKDGETQQRWCNTCQIHFTGDLIKHRRTQEHKLAKRSLRPFCTVCSRHFKTPRKFVEHMKSPEHKQKAKEVRLGEKELGSPEDSEELITVDAVGCFEDDEEEEEEEEEEEGTGEGEDLDVVLVENEDSAAKQTGLKEVSLEDYKGSEKYCPDTAYGLDFLVPVAGYLCRLCHKFYHSDSAARLAHCKSLMHFENFQRYKVARHRATAAYPEAPLHSQGSGSQLLDDQKQPPATTEDSSKKTNANHGIDKEGTELSALQEQALRSPEGKGKLATAVAESKSLASVTDVCGITVVEESLQESKSTATCPLPEESSAAGELLGHAVYEEEEANAARQGEGTDYCQDPGSGGGLGQKEASNVGQEAAAEPSSLAKGEAASLTSAGCRRSSRRKPR", "length": 723, "header": "tr|A0A8V1AFD7-1|A0A8V1AFD7_CHICK Computationally mapped isoform of CDKN1A interacting zinc finger protein 1 OS=Gallus gallus OX=9031 GN=CIZ1 PE=4 SV=1 CANONICAL=A0A8V1AJK6-1" }, "locus": { "chromosome": "17", "start_pos": 5775561, "end_pos": 5758719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068220.1", "url": "https://www.ensembl.org/id/ENSGALT00010068220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041963.1", "url": "https://www.ensembl.org/id/ENSGALP00010041963.1" } ] } }, { "isoform_ac": "A0A8V1AJK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6/entry#A0A8V1AJK6-1", "sequence": { "sequence": "MFNQQQFQQHHHHPPAQQGGRGLPPPPPPPPQQQQMLSLRATNQPSLLNANPMLQRALLMQQMQGNLRGFNMTAPALQQFFPQATRHSLLGPPPVGVSLKPTRLGFPNLPFQRQNRMFRKDFQRVPDRKRELDAGSSSHMHGDEKIEFRGELRAGSEQNNSLSTEPRTPAEAVLNTEPAAKRLKSVTEESALENAAGSKEELSTHVQADGTNNVKQYAAESLSKERKFSEEPKAPEVLSSGGSLKVTIQQSSESRAISTTALKPGQWTCEMGTADASPESALKFYCYICKTNCCNQQNFQAHMAGIQHQQRLGEIQHMSNVCFVSLLPMVKEQKLLAEKDGETQQRWCNTCQIHFTGDLIKHRRTQEHKLAKRSLRPFCTVCSRHFKTPRKFVEHMKSPEHKQKAKEVRLGEKELGSPEDSEELITVDAVGCFEDDEEEEEEEEEEEGTGEGEDLDVVLVENEDSAAKQTGLKEVSLEDYKGSEKYCPDTAYGLDFLVPVAGYLCRLCHKFYHSDSAARLAHCKSLMHFENFQRYKVARHRATAAYPEAPLHSQGSGSQLLDDQKQPPATTEDSSKKTNANHGIDKEGTELSALQEQALRSPEGKGKLATAVAESKSLASVTDVCGITVVEESLQESKSTATCPLPEESSAAGELLGHAVYEEEEANAARQGEGTDYCQDPGSGGGLGQKEASNVGQEAAAEPSSLAKGEAASLTSAGCRRSSRRKPR", "length": 728, "header": "tr|A0A8V1AJK6-1|A0A8V1AJK6_CHICK Isoform 1 of CDKN1A interacting zinc finger protein 1 OS=Gallus gallus OX=9031 GN=CIZ1 PE=4 SV=1 CANONICAL=A0A8V1AJK6-1" }, "locus": { "chromosome": "17", "start_pos": 5775561, "end_pos": 5757061, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068222.1", "url": "https://www.ensembl.org/id/ENSGALT00010068222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041965.1", "url": "https://www.ensembl.org/id/ENSGALP00010041965.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK6" } ], "pmid": "" } ] }, { "name": "Molecular Function", 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJL8-1", "uniprot_ac": "A0A8V1AJL8", "uniprot_id": "A0A8V1AJL8_CHICK", "mass": { "chemical_mass": 43275.0, "monoisotopic_mass": 43275.0 }, "refseq": { "ac": "XP_040505993", "name": "DNA repair protein RAD51 homolog 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505993" }, "gene_names": [ { "name": "RAD51D", "type": "recommended", "evidence": [ { "id": "A0A8V1AJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ] }, { "name": "RAD51D", "type": "synonym", "evidence": [ { "id": "XP_040505993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505993" } ] }, { "name": "RAD51L3", "type": "synonym", "evidence": [ { "id": "XP_040505993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505993" } ] } ], "protein_names": [ { "name": "DNA repair protein RAD51 homolog 4", "type": "recommended", "evidence": [ { "id": "A0A8V1AJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8/entry#names_and_taxonomy" } ] }, { "name": "DNA repair protein RAD51 homolog 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040505993", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505993" } ] }, { "name": "R51H3", "type": "synonym", "evidence": [ { "id": "A0A8V1AJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8/entry#names_and_taxonomy" } ] }, { "name": "RAD51 homolog D", "type": "synonym", "evidence": [ { "id": "A0A8V1AJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8/entry#names_and_taxonomy" } ] }, { "name": "RAD51-like protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505993" } ] }, { "annotation": "Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8#function" }, { "database": "UniProtKB", "id": "ARBA00057808", "url": "https://www.uniprot.org/uniprotkb/ARBA00057808#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAD51D", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8", "locus": { "chromosome": "19", "start_pos": 4971692, "end_pos": 4960058, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029630", "url": "https://www.ensembl.org/id/ENSGALG00010029630" } ] } } ], "crossref": [ { "id": "A0A8V1AJL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19489", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19489", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417528", "url": "https://www.ncbi.nlm.nih.gov/gene/417528", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QRIHTFR", "url": "https://omabrowser.org/oma/group/QRIHTFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJL8", "url": "https://www.orthodb.org/?gene=A0A8V1AJL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN24", "url": "https://www.orthodb.org/?gene=A0A8V1AN24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APJ6", "url": "https://www.orthodb.org/?gene=A0A8V1APJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46457", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46457", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46457:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46457:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5685942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693537", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693568", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693579", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693616", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040505993", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN24", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGVVWVALKGHPLGVTRHHCSVGGPMGMLRAVCPHGPPWYPRVRYGTPWVPIPSPHRSLRFHPRSAPSHSAGAMVVLRAGLCPGLTEEMIQLLRANNIRTVVDFVSSDLEDVAQSCSLSYKALVAVRRVLLAQFSAFPTNGADLYEELKSSTAILPTGNPSLDQLLDAGLYTGEVTELAGAPGSGKTQVCLSIAASVSLGLRQHVFFLDSTGGFTASRLYQMLQARVEDKEEQLEALQRVQVVRMFDIYEMLRALHEVRDCLSQQVESSAGPLKAVLIDSVSAVLSPLLGGRQSEGLAIMMQLARELKTLAKEFSVAVVVTNQVTRDSSTGALKSALGRSWSFVPSTRVLLQGRAVPWEEGAAPHTACLAKSPRQPTGMQVQLDIGSDAVQEQRPVTPTP", "length": 402, "header": "tr|A0A8V1AJL8-1|A0A8V1AJL8_CHICK Isoform 1 of DNA repair protein RAD51 homolog 4 OS=Gallus gallus OX=9031 GN=RAD51D PE=3 SV=1 CANONICAL=A0A8V1AJL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8/entry#A0A8V1AJL8-1", "sequence": { "sequence": "MAAGVVWVALKGHPLGVTRHHCSVGGPMGMLRAVCPHGPPWYPRVRYGTPWVPIPSPHRSLRFHPRSAPSHSAGAMVVLRAGLCPGLTEEMIQLLRANNIRTVVDFVSSDLEDVAQSCSLSYKALVAVRRVLLAQFSAFPTNGADLYEELKSSTAILPTGNPSLDQLLDAGLYTGEVTELAGAPGSGKTQVCLSIAASVSLGLRQHVFFLDSTGGFTASRLYQMLQARVEDKEEQLEALQRVQVVRMFDIYEMLRALHEVRDCLSQQVESSAGPLKAVLIDSVSAVLSPLLGGRQSEGLAIMMQLARELKTLAKEFSVAVVVTNQVTRDSSTGALKSALGRSWSFVPSTRVLLQGRAVPWEEGAAPHTACLAKSPRQPTGMQVQLDIGSDAVQEQRPVTPTP", "length": 402, "header": "tr|A0A8V1AJL8-1|A0A8V1AJL8_CHICK Isoform 1 of DNA repair protein RAD51 homolog 4 OS=Gallus gallus OX=9031 GN=RAD51D PE=3 SV=1 CANONICAL=A0A8V1AJL8-1" }, "locus": { "chromosome": "19", "start_pos": 4963845, "end_pos": 4960257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071643.1", "url": "https://www.ensembl.org/id/ENSGALT00010071643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044333.1", "url": "https://www.ensembl.org/id/ENSGALP00010044333.1" } ] } }, { "isoform_ac": "A0A8V1AN24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8/entry#A0A8V1AN24-1", "sequence": { "sequence": "MVVLRAGLCPGLTEEMIQLLRANNIRTVVDFVSSDLEDVAQSCSLSYKALVAVRRVLLAQFSAFPTNGADLYEELKSSTAILPTGNPSLDQLLDAGLYTGEVTELAGAPGSGKTQVCLSIAASVSLGLRQHVFFLDSTGGFTASRLYQMLQARVEDKEEQLEALQRVQVVRMFDIYEMLRALHEVRDCLSQQVESSAGPLKAVLIDSVSAVLSPLLGGRQSEGLAIMMQLARELKTLAKEFSVAVVVGSNNHFMFNNPGSALVDVNSSCALVVCCPASAGSLHRCLKCLARSFNILL", "length": 297, "header": "tr|A0A8V1AN24-1|A0A8V1AN24_CHICK Computationally mapped isoform of RAD51 paralog D OS=Gallus gallus OX=9031 GN=RAD51D PE=3 SV=1 CANONICAL=A0A8V1AJL8-1" }, "locus": { "chromosome": "19", "start_pos": 4971652, "end_pos": 4960482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071644.1", "url": "https://www.ensembl.org/id/ENSGALT00010071644.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044334.1", "url": "https://www.ensembl.org/id/ENSGALP00010044334.1" } ] } }, { "isoform_ac": "A0A8V1APJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8/entry#A0A8V1APJ6-1", "sequence": { "sequence": "MVVLRAGLCPGLTEEMIQLLRANNIRTGNLVGDVGFCRFGVSPHVPPVYSPSAVLMVVIQFLLSVPFAVVDFVSSDLEDVAQSCSLSYKALVAVRRVLLAQFSAFPTNGADLYEELKSSTAILPTGNPSCHQPQPGCCPLRAEVTFHVLWL", "length": 151, "header": "tr|A0A8V1APJ6-1|A0A8V1APJ6_CHICK Computationally mapped isoform of RAD51 paralog D OS=Gallus gallus OX=9031 GN=RAD51D PE=4 SV=1 CANONICAL=A0A8V1AJL8-1" }, "locus": { "chromosome": "19", "start_pos": 4961150, "end_pos": 4960482, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071642.1", "url": "https://www.ensembl.org/id/ENSGALT00010071642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044332.1", "url": "https://www.ensembl.org/id/ENSGALP00010044332.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-GGA-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-GGA-5693568", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693568", "resource": "Reactome", "description": "Resolution of D-loop Structures through Holliday Junction Intermediates" }, { "id": "R-GGA-5693579", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693579", "resource": "Reactome", "description": "Homologous DNA Pairing and Strand Exchange" }, { "id": "R-GGA-5693616", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693616", "resource": "Reactome", "description": "Presynaptic phase of homologous DNA pairing and strand exchange" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R474-1", "protein_name": "DNA repair protein", "gene_name": "rad51d", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVVLREGICPGINEDFIKALQTEDIRTVEDFVSWNPEELAQKCSLSYKALVAVRRVLLAQYTAYPISGADLYEELLSSTAILSTGSPSLDKLLDSGLYTGEITELTGSPGSGKTQVCFSVAVNISHQLKQTVVYIDTKGGMCANRLLQMLQTKTSNEQEQMEALQKIKVFRVFDVFSLLACLQNLRSTGLQKTSVGGGSVKALMVDSVSAVLSPILGGKQNEGMSLLMQVAGELKMIAKDFNIAVLVTNHVTKDGNGQLKAGLGLSWSHVPRTRVLLQRVENEETSSLRTATLTKSSRQACHMTKVFDLCHWSEERTTSISGKRKLD", "length": 327 }, "evidence": [ { "id": "A0A8V1AJL8", "url": "https://omabrowser.org/oma/group/A0A8V1AJL8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3GTU6-1", "protein_name": "DNA repair protein RAD51 homolog 4", "gene_name": "Rad51d", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGVLRVGLCPGLTEEIVQLLKGQRIKTVADLAAANLEEVAQKCGLSYKALVALRRVLLAQFSAFPLNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCVAANVAHSLQQNVLYVDSSGGMTASRLLQLLQARTQDEEKQAGALQRIQVVHVFDIFQMLDMLQDLRGSMAQQSTSSSGTVKVVIVDSVTAVIAPLLGGQQREGLALMMQLARELKILARDLAVAVVVTNHLTRDRDGRRFKPALGRSWSFVPSTRILLDVTKGAGTLGRGQRTVCLTKSPRQPTGLQEVIDIGTLGTEEQSPELPAKQT", "length": 329 }, "evidence": [ { "id": "A0A8V1AJL8", "url": "https://omabrowser.org/oma/group/A0A8V1AJL8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O55230-1", "protein_name": "DNA repair protein RAD51 homolog 4", "gene_name": "Rad51d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGMLRAGLCPGLTEETVQLLRGRKIKTVADLAAADLEEVAQKCGLSYKALVALRRVLLAQFSAFPLNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCVAANVAHSLQQNVLYVDSNGGMTASRLLQLLQARTQDEEKQASALQRIQVVRSFDIFRMLDMLQDLRGTIAQQEATSSGAVKVVIVDSVTAVVAPLLGGQQREGLALMMQLARELKILARDLGVAVVVTNHLTRDWDGRRFKPALGRSWSFVPSTRILLDVTEGAGTLGSSQRTVCLTKSPRQPTGLQEMIDIGTLGTEEQSPELPGKQT", "length": 329 }, "evidence": [ { "id": "A0A8V1AJL8", "url": "https://omabrowser.org/oma/group/A0A8V1AJL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75771-1", "protein_name": "DNA repair protein RAD51 homolog 4", "gene_name": "RAD51D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQFSAFPVNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCMAANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQVVHAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLARDLGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSATLQGDQT", "length": 328 }, "evidence": [ { "id": "A0A8V1AJL8", "url": "https://omabrowser.org/oma/group/A0A8V1AJL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1ZXF0-1", "protein_name": "Probable DNA repair protein RAD51 homolog 4", "gene_name": "rad51d", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEEESISGLEVRFYQTQCLSEDNVIKFENNGYPMIDLILFSDAYQIQRNTSIPIETVTLIQRNLQRLFSSVPINGYQHYLDVKEFKTHYSSGIKLLDQLLGGNGFTSGEIYELVGNTSCGKTQISMCCSLNLSQQYNSNIIYIDSSNSFSPPRLIEIFKSNYLIKQRQKQQQKQQQKQHQKQQENNDKIEQDKILKILDRIKVFNCFDSITLLELLSTIDSTLSIISDEIPTFENQFYKGLKMVVIDSIGTLLAPIIGGKQTQGHYTMMMISRLIKYIADTYQIIFLITNNTVGGNSFDNKAALGEAWSMVPNHQLMINHQYNDDENEERSIYIEKSTRLPVSIIFIINLYWLF", "length": 354 }, "evidence": [ { "id": "A0A8V1AJL8", "url": "https://omabrowser.org/oma/group/A0A8V1AJL8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8CIN9-1", "protein_name": "E3 ubiquitin-protein ligase rififylin", "gene_name": "Rffl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWASCCNWFCLDGQPEETPPPQGARTQAYSNPGYSSFPSPTGSEPSCKACGVHFASTTRKQTCLDCKKNFCMTCSSQEGNGPRLCLLCLRFRATAFQREELMKMKVKDLRDYLSLHDISTEMCREKEELVFLVLGQQPVISEADRTRAPTLPQAFPEQQAFLTQPQSSTVPPTSPGLPSSPAQVTSVLAQDQETQQAIGHVSQDHEEPIFLESTARVPPEDETQSVDSEDSFVPGRRASLSDLTHLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGNEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVFRS", "length": 362 }, "evidence": [ { "id": "A0A8V1AJL8", "url": "https://omabrowser.org/oma/group/A0A8V1AJL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9LQQ2-1", "protein_name": "DNA repair protein RAD51 homolog 4", "gene_name": "RAD51D", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPLKHLEKENPIIDACFQDFCASHGILTIEDFLLHDLYELTAFSQRQTNADRLKEGITLILSLIERQCRPLVNGLKLLEDLHRNKHTLSTGDKETDSLLQGGFREGQLTELVGPSSSGKTQFCMQAAASVAENHLGRVLYLDTGNSFSARRIAQFICSSSDATLGQKVMSRILCHTVYDIYTLFDTLQDLEITLRLQMNVNESRLRLLVVDSISSLITPILGGSGSQGRALMVAIGYLLKKLAHEHSIAILVTNHTVGAGGEGGKTKPALGETWKSIPHVRLSLSRDHKNSNCTISILKHTSLPSGQAAKTLTRKENQQCP", "length": 322 }, "evidence": [ { "id": "A0A8V1AJL8", "url": "https://omabrowser.org/oma/group/A0A8V1AJL8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "Rad51B-Rad51C-Rad51D-XRCC2 complex", "id": "GO:0033063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "DNA strand invasion", "id": "GO:0042148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042148", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "supramolecular fiber organization", "id": "GO:0097435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL8" }, { "id": "PS50162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecA family profile 1", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 326, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 399, 401 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJM2-1", "uniprot_ac": "A0A8V1AJM2", "uniprot_id": "A0A8V1AJM2_CHICK", "mass": { "chemical_mass": 40110.0, "monoisotopic_mass": 40110.0 }, "refseq": { "ac": "XP_004946243", "name": "allergin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946243" }, "gene_names": [ { "name": "MILR1", "type": "recommended", "evidence": [ { "id": "A0A8V1AJM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2" } ] }, { "name": "MILR1", "type": "synonym", "evidence": [ { "id": "XP_004946243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946243" } ] } ], "protein_names": [ { "name": "Mast cell immunoglobulin like receptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AJM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2/entry#names_and_taxonomy" } ] }, { "name": "allergin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004946243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946243" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946243.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946243" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MILR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417417", "url": "https://www.ncbi.nlm.nih.gov/gene/417417", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417417", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417417", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEIHYAT", "url": "https://omabrowser.org/oma/group/HEIHYAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE89", "url": "https://www.orthodb.org/?gene=A0A8V1AE89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE93", "url": "https://www.orthodb.org/?gene=A0A8V1AE93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJM2", "url": "https://www.orthodb.org/?gene=A0A8V1AJM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN27", "url": "https://www.orthodb.org/?gene=A0A8V1AN27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APJ8", "url": "https://www.orthodb.org/?gene=A0A8V1APJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44337:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44337:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44337:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44337:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AE89", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN27", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLQLIFPHVQTLSSDHWASSRKRYQRKKNQRTDSWRAQSTQQIQNATADYREILSNPMLTPLHGTLEVVMKQEVSLSCHLDSGSPPVRYTLFKNRQKLSALNRTDLTPVLFNLTINSASDVGEYKCKAQNEISNSEKYSRSLNFTLKEPVSKPVLSSPNSQAKKGQNVTLSCLSENGSLPITYTFFKDRQSIQPPVKMQNREAAVISVLIKSSNDFGMYKCKAENCFHNKTKYSNGFNFTLAEERSNSQPLIICLGLTLLLLAIGFALAIPFFIIPLYKAKKFTPTRSSTGHTSKEKVEESEDYVTYAEIEPIQPEACVNLSVIRRDEQENRACATIYSEVLVGEGAQAGPLHSPE", "length": 357, "header": "tr|A0A8V1AJM2-1|A0A8V1AJM2_CHICK Isoform 1 of Mast cell immunoglobulin like receptor 1 OS=Gallus gallus OX=9031 GN=MILR1 PE=4 SV=1 CANONICAL=A0A8V1AJM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2/entry#A0A8V1AE89-1", "sequence": { "sequence": "MFYFILLLFPYSQSTQQIQNATADYREILSNPMLTPLHGTLEVVMKQEVSLSCHLDSGSPPVRYTLFKNRQKLSALNRTDLTPVLFNLTINSASDVGEYKCKAQNEISNSEKYSRSLNFTLKEPVSKPVLSSPNSQAKKGQNVTLSCLSENGSLPITYTFFKDRQSIQPPVKMQNREAAVISVLIKSSNDFGMYKCKAENCFHNKTKYSNGFNFTLAEERSNSQPLIICLGLTLLLLAIGFALAIPFFIIPLYKAKKFTPTRSSTGHTSKEKVEESEDYVTYAEIEPIQPEACVNLSVIRRDEQENRACATIYSEVLVGEGAQAGPLHSPE", "length": 331, "header": "tr|A0A8V1AE89-1|A0A8V1AE89_CHICK Computationally mapped isoform of Mast cell immunoglobulin like receptor 1 OS=Gallus gallus OX=9031 GN=MILR1 PE=4 SV=1 CANONICAL=A0A8V1AJM2-1" }, "locus": { "chromosome": "18", "start_pos": 7512021, "end_pos": 7507111, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071641.1", "url": "https://www.ensembl.org/id/ENSGALT00010071641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044331.1", "url": "https://www.ensembl.org/id/ENSGALP00010044331.1" } ] } }, { "isoform_ac": "A0A8V1AE93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2/entry#A0A8V1AE93-1", "sequence": { "sequence": "MLTPLHGTLEVVMKQEVSLSCHLDSGSPPVRYTLFKNRQKLSALNRTDLTPVLFNLTINSASDVGEYKCKAQNEISNSEKYSRSLNFTLKEPVSKPVLSSPNSQAKKGQNVTLSCLSENGSLPITYTFFKDRQSIQPPVKMQNREAAVISVLIKSSNDFGMYKCKAENCFHNKTKYSNGFNFTLAEERSNSQPLIICLGLTLLLLAIGFALAIPFFIIPLYKAKKFTPTRSSTGHTSKEKVEESEDYVTYAEIEPIQPEACVNLSVIRRDEQENRACATIYSEVLVGEGAQAGPLHSPE", "length": 299, "header": "tr|A0A8V1AE93-1|A0A8V1AE93_CHICK Computationally mapped isoform of Mast cell immunoglobulin like receptor 1 OS=Gallus gallus OX=9031 GN=MILR1 PE=4 SV=1 CANONICAL=A0A8V1AJM2-1" }, "locus": { "chromosome": "18", "start_pos": 7512021, "end_pos": 7508143, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071646.1", "url": "https://www.ensembl.org/id/ENSGALT00010071646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044336.1", "url": "https://www.ensembl.org/id/ENSGALP00010044336.1" } ] } }, { "isoform_ac": "A0A8V1AJM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2/entry#A0A8V1AJM2-1", "sequence": { "sequence": "MNLQLIFPHVQTLSSDHWASSRKRYQRKKNQRTDSWRAQSTQQIQNATADYREILSNPMLTPLHGTLEVVMKQEVSLSCHLDSGSPPVRYTLFKNRQKLSALNRTDLTPVLFNLTINSASDVGEYKCKAQNEISNSEKYSRSLNFTLKEPVSKPVLSSPNSQAKKGQNVTLSCLSENGSLPITYTFFKDRQSIQPPVKMQNREAAVISVLIKSSNDFGMYKCKAENCFHNKTKYSNGFNFTLAEERSNSQPLIICLGLTLLLLAIGFALAIPFFIIPLYKAKKFTPTRSSTGHTSKEKVEESEDYVTYAEIEPIQPEACVNLSVIRRDEQENRACATIYSEVLVGEGAQAGPLHSPE", "length": 357, "header": "tr|A0A8V1AJM2-1|A0A8V1AJM2_CHICK Isoform 1 of Mast cell immunoglobulin like receptor 1 OS=Gallus gallus OX=9031 GN=MILR1 PE=4 SV=1 CANONICAL=A0A8V1AJM2-1" }, "locus": { "chromosome": "18", "start_pos": 7512021, "end_pos": 7506112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071648.1", "url": "https://www.ensembl.org/id/ENSGALT00010071648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044338.1", "url": "https://www.ensembl.org/id/ENSGALP00010044338.1" } ] } }, { "isoform_ac": "A0A8V1AN27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2/entry#A0A8V1AN27-1", "sequence": { "sequence": "MNLQLIFPHVQTLSSDHWASSRKRYQRKKNQRTDSWRAQSTQQIQNATADYREILSNPMLTPLHGTLEVVMKQEVSLSCHLDSGSPPVRYTLFKNRQKLSALNRTDLTPVLFNLTINSASDVGEYKCKAQNEISNSEKYSRSLNFTLKEPVSKPVLSSPNSQAKKGQNVTLSCLSENGSLPITYTFFKDRQSIQPPVKMQNREAAVISVLIKSSNDFGMYKCKAENCFHNKTKYSNGFNFTLAEERSNSQPLIICLGLTLLLLAIGFALAIPFFIIPLYKAKKFTPTRSSTGHTSKEKVEESEDYVTYAEIENRACATIYSEVLVGEGAQAGPLHSPE", "length": 338, "header": "tr|A0A8V1AN27-1|A0A8V1AN27_CHICK Computationally mapped isoform of Mast cell immunoglobulin like receptor 1 OS=Gallus gallus OX=9031 GN=MILR1 PE=4 SV=1 CANONICAL=A0A8V1AJM2-1" }, "locus": { "chromosome": "18", "start_pos": 7512021, "end_pos": 7506112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071649.1", "url": "https://www.ensembl.org/id/ENSGALT00010071649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044339.1", "url": "https://www.ensembl.org/id/ENSGALP00010044339.1" } ] } }, { "isoform_ac": "A0A8V1APJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2/entry#A0A8V1APJ8-1", "sequence": { "sequence": "MNLQLIFPHVQTLSSDHWASSRKRYQRKKNQRTDSWRAQSTQQIQNATADYREILSNPMLTPLHGTLEVVMKQEVSLSCHLDSGSPPVRYTLFKNRQKLSALNRTDLTPVLFNLTINSASDVGEYKCKAQNEISNSEKYSRSLNFTLKEPVSKPVLSSPNSQAKKGQNVTLSCLSENGSLPITYTFFKDRQSIQPPVKMQNREAAVISVLIKSSNDFGMYKCKAENCFHNKTKYSNGFNFTLAEERSNSQPLIICLGLTLLLLAIGFALAIPFFIIPLYKAKPIQPEACVNLSVIRRDEQENRACATIYSEVLVGEGAQAGPLHSPE", "length": 327, "header": "tr|A0A8V1APJ8-1|A0A8V1APJ8_CHICK Computationally mapped isoform of Mast cell immunoglobulin like receptor 1 OS=Gallus gallus OX=9031 GN=MILR1 PE=4 SV=1 CANONICAL=A0A8V1AJM2-1" }, "locus": { "chromosome": "18", "start_pos": 7512021, "end_pos": 7506112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071647.1", "url": "https://www.ensembl.org/id/ENSGALT00010071647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044337.1", "url": "https://www.ensembl.org/id/ENSGALP00010044337.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417417", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417417", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BHD8-1", "protein_name": "Mast cell immunoglobulin like receptor 1", "gene_name": "MILR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWKKSLLMFLFSLPVQKAALDCERMRKTNEFSSPNLESKTHEVMRGQNVSLFCSHKNNSLEITYNLFLGGKNLGCHDRKGEPATFNLTISEARDLGPYKCKAQVSNCSKYSYEFNFTFVDPVAAPVLNISVIQTKTDQYIMLHCISFNGSLPINYTFFEENITISPTISKDVREPAEFNLTKSNTGEGKEYRCEAKNRLPNHAKYSQFVTIPLIGGDSCPFCLQLLLPGLLLLVLIVIILVLAFWMLPKYKARKAMKENKSRVYENTSMEAGIYANICSKQEDEESVPDLESRQCVPIAQDETEGSQEIHYATPAFQAVAPRDWEASNDYKTDYVYTELNF", "length": 341 }, "evidence": [ { "id": "A0A8V1AJM2", "url": "https://omabrowser.org/oma/group/A0A8V1AJM2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z6M3-1", "protein_name": "Allergin-1", "gene_name": "MILR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWSHLNRLLFWSIFSSVTCRKAVLDCEAMKTNEFPSPCLDSKTKVVMKGQNVSMFCSHKNKSLQITYSLFRRKTHLGTQDGKGEPAIFNLSITEAHESGPYKCKAQVTSCSKYSRDFSFTIVDPVTSPVLNIMVIQTETDRHITLHCLSVNGSLPINYTFFENHVAISPAISKYDREPAEFNLTKKNPGEEEEYRCEAKNRLPNYATYSHPVTMPSTGGDSCPFCLKLLLPGLLLLLVVIILILAFWVLPKYKTRKAMRNNVPRDRGDTAMEVGIYANILEKQAKEESVPEVGSRPCVSTAQDEAKHSQELQYATPVFQEVAPREQEACDSYKSGYVYSELNF", "length": 343 }, "evidence": [ { "id": "A0A8V1AJM2", "url": "https://omabrowser.org/oma/group/A0A8V1AJM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 144, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 230, 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJM7-1", "uniprot_ac": "A0A8V1AJM7", "uniprot_id": "A0A8V1AJM7_CHICK", "mass": { "chemical_mass": 21481.0, "monoisotopic_mass": 21481.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AJM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERANTITYLKGETIGTEMRKKGNKGCAATGLEKFPKNINRLHVTQLSIVCPFKYLVYMERQRKERPKKKQQMYCTGHEVSRKKSTTQVMRLKARRSAISPGETTNAIHKEPEGVPAKDKAWRNKSSGHYPSAVETVNQKVSPYKHKHFKHCHSLSENSDRFKLNFFFSKSASLALLHLENQRRSF", "length": 186, "header": "tr|A0A8V1AJM7-1|A0A8V1AJM7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AJM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM7/entry#A0A8V1AJM7-1", "sequence": { "sequence": "MERANTITYLKGETIGTEMRKKGNKGCAATGLEKFPKNINRLHVTQLSIVCPFKYLVYMERQRKERPKKKQQMYCTGHEVSRKKSTTQVMRLKARRSAISPGETTNAIHKEPEGVPAKDKAWRNKSSGHYPSAVETVNQKVSPYKHKHFKHCHSLSENSDRFKLNFFFSKSASLALLHLENQRRSF", "length": 186, "header": "tr|A0A8V1AJM7-1|A0A8V1AJM7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AJM7-1" }, "locus": { "chromosome": "17", "start_pos": 6826356, "end_pos": 6824833, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068248.1", "url": "https://www.ensembl.org/id/ENSGALT00010068248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041991.1", "url": "https://www.ensembl.org/id/ENSGALP00010041991.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJM9-1", "uniprot_ac": "A0A8V1AJM9", "uniprot_id": "A0A8V1AJM9_CHICK", "mass": { "chemical_mass": 55074.0, "monoisotopic_mass": 55074.0 }, "refseq": { "ac": "XP_024997747", "name": "inositol polyphosphate 5-phosphatase K isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997747" }, "gene_names": [ { "name": "INPP5K", "type": "recommended", "evidence": [ { "id": "A0A8V1AJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9" } ] }, { "name": "INPP5K", "type": "synonym", "evidence": [ { "id": "XP_024997747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997747" } ] } ], "protein_names": [ { "name": "Inositol polyphosphate-5-phosphatase K", "type": "synonym", "evidence": [ { "id": "A0A8V1AJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9/entry#names_and_taxonomy" } ] }, { "name": "inositol polyphosphate 5-phosphatase K isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024997747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997747" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997747.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997747" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INPP5K", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9", "locus": { "chromosome": "19", "start_pos": 5746699, "end_pos": 5762799, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029338", "url": "https://www.ensembl.org/id/ENSGALG00010029338" } ] } } ], "crossref": [ { "id": "A0A8V1AJM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09094", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09094", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771549", "url": "https://www.ncbi.nlm.nih.gov/gene/771549", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NSECQHI", "url": "https://omabrowser.org/oma/group/NSECQHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJM9", "url": "https://www.orthodb.org/?gene=A0A8V1AJM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALQ2", "url": "https://www.orthodb.org/?gene=A0A8V1ALQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11200", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11200", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11200:SF117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11200:SF117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024997747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSEQHSSAQRDAVRELRLHLVTWNVGTASPPPDVTSLLQLDSPSPAIDMYVIGLQEVNSRITNFLSDLVFDDPWSIFFMTVLSPLGYIKLSSIRMQGLLLLIFVKHDHLPFIRDVRTNYTRTGLYGYWGNKGGVTVRMSLYGHTICFINCHLPAHMENTEQRLDDFEKILEMQFEEENVPSTLDHDVLFWFGDLNFRIADYGIHFVRESINNKRYNLLWEKDQLNMAKKKEAFLQEFIEGPLQFKPTYKFDLHSDVYDTREQKSLFWFNEKKRKPAWTDRILWRVKSLCQHASKEDDFSEEEQTISVTLNNYISHMSYGISDHKPVTGTFGIELKPLLSDPLVTLSPEGEWSSERDVFISYSAVPGFPSSAWDWIGLFKVTFRHANDYVTYAWVEDDEISSNEDSKQVYMSAAEIPDMGGKFLLCYYSNNLQSIVGISQPFQIQPNRTSIGKDLAQEENAWMQKPDNLESHNEF", "length": 475, "header": "tr|A0A8V1AJM9-1|A0A8V1AJM9_CHICK Isoform 1 of Inositol polyphosphate-5-phosphatase K OS=Gallus gallus OX=9031 GN=INPP5K PE=1 SV=1 CANONICAL=A0A8V1AJM9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9/entry#A0A8V1AJM9-1", "sequence": { "sequence": "MDSEQHSSAQRDAVRELRLHLVTWNVGTASPPPDVTSLLQLDSPSPAIDMYVIGLQEVNSRITNFLSDLVFDDPWSIFFMTVLSPLGYIKLSSIRMQGLLLLIFVKHDHLPFIRDVRTNYTRTGLYGYWGNKGGVTVRMSLYGHTICFINCHLPAHMENTEQRLDDFEKILEMQFEEENVPSTLDHDVLFWFGDLNFRIADYGIHFVRESINNKRYNLLWEKDQLNMAKKKEAFLQEFIEGPLQFKPTYKFDLHSDVYDTREQKSLFWFNEKKRKPAWTDRILWRVKSLCQHASKEDDFSEEEQTISVTLNNYISHMSYGISDHKPVTGTFGIELKPLLSDPLVTLSPEGEWSSERDVFISYSAVPGFPSSAWDWIGLFKVTFRHANDYVTYAWVEDDEISSNEDSKQVYMSAAEIPDMGGKFLLCYYSNNLQSIVGISQPFQIQPNRTSIGKDLAQEENAWMQKPDNLESHNEF", "length": 475, "header": "tr|A0A8V1AJM9-1|A0A8V1AJM9_CHICK Isoform 1 of Inositol polyphosphate-5-phosphatase K OS=Gallus gallus OX=9031 GN=INPP5K PE=1 SV=1 CANONICAL=A0A8V1AJM9-1" }, "locus": { "chromosome": "19", "start_pos": 5762662, "end_pos": 5749297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070957.1", "url": "https://www.ensembl.org/id/ENSGALT00010070957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043648.1", "url": "https://www.ensembl.org/id/ENSGALP00010043648.1" } ] } }, { "isoform_ac": "A0A8V1ALQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJM9/entry#A0A8V1ALQ2-1", "sequence": { "sequence": "MDSEQHSSAQRDAVRELRLHLVTWNVGTASPPPDVTSLLQLDSPSPAIDILQEVNSRITNFLSDLVFDDPWSIFFMTVLSPLGYIKLSSIRMQGLLLLIFVKHDHLPFIRDVRTNYTRTGLYGYWGNKGGVTVRMSLYGHTICFINCHLPAHMENTEQRLDDFEKILEMQFEEENVPSTLDHDVLFWFGDLNFRIADYGIHFVRESINNKRYNLLWEKDQLNMAKKKEAFLQEFIEGPLQFKPTYKFDLHSDVYDTSEKKRKPAWTDRILWRVKSLCQHASKEDDFSEEEQTISVTLNNYISHMSYGISDHKPVTGTFGIELKPLLSDPLVTLSPEGEWSSERDVFISYSAVPGFPSSAWDWIGLFKVTFRHANDYVTYAWVEDDEISSNEDSKQVYMSAAEIPDMGGKFLLCYYSNNLQSIVGISQPFQIQPNRTSIGKDLAQEENAWMQKPDNLESHNEF", "length": 462, "header": "tr|A0A8V1ALQ2-1|A0A8V1ALQ2_CHICK Computationally mapped isoform of Inositol polyphosphate-5-phosphatase K OS=Gallus gallus OX=9031 GN=INPP5K PE=1 SV=1 CANONICAL=A0A8V1AJM9-1" }, "locus": { "chromosome": "19", "start_pos": 5762662, "end_pos": 5749297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070956.1", "url": "https://www.ensembl.org/id/ENSGALT00010070956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043647.1", "url": "https://www.ensembl.org/id/ENSGALP00010043647.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2Z2-1", "protein_name": "Inositol polyphosphate 5-phosphatase K", "gene_name": "Inpp5k", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTASLRKPSAPKELMLSIHVVTWNVASAAPTVDLSDLLQLNNEDLNLDIYIIGLQEMNYGIISLLSDAAFEDPWSSFFMDMLSPLNLVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSIPTGLYGYWGNKGGINICLKLYGYYVSIVNCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFGLLFVQECITKKRYKELWEKDQLFIAKKQDQLLREFQEGPLLFPPTYKFDRHSNNYDTSEKKRKPAWTDRILWRLKRQPAKANPSGFLLTQKDYVSHMTYSISDHKPVTGTFDLELNPLMSVPLITMMPEYLWTKENDMLINYTSTPEFLSSPWDWIGLYKVGMRHINDYVSYVWVGDNQVSRGNNPNQVYINISAIPDTEEQFLLCYYSNNLHSIVGISQPFKIPSGFFLREDTLSELEPQL", "length": 446 }, "evidence": [ { "id": "A0A8V1AJM9", "url": "https://omabrowser.org/oma/group/A0A8V1AJM9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HTF6-1", "protein_name": "Inositol polyphosphate 5-phosphatase K", "gene_name": "Inpp5k", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKSAACLRRPSTPKVSVLSIHVVTWNVASAAPTVDLSDLLQLNSQDLNLDIYIIGLQEMNSGIISLLSDAAFEDPWSTLFMDVLSRLHFVKVSQVRMQGLLLLVFAKYQHLPFIQIISTKSIPTGFYGYWGNKGGVNICLKLYGYYVSIINCHLPPHMSNNDQRLEHFDRILESQTFEGSDVPNILDHDLILWFGDMNFRIEDFGLLFVQECITKQYYQELWEKDQLRIAKRRDPLLREFQEGPLLFPPTYKFDRHSNNYDTSEKKRKPAWTDRILWRLKRQPQTSPLVSRLPSSYFSLTLKSYVSHMTYSISDHKPVTGTFNLELNPRMSVPLITMMPECLWTMENDMLISYTSTPEFLSSPWDWIGLYKVGMRHINDYVSYAWVGDNQVSYGNHPHQVYINISNVPETEDQFLLCYYSNNLHSVVGISQPFKIPLRFFLRDDTLSDPQI", "length": 451 }, "evidence": [ { "id": "A0A8V1AJM9", "url": "https://omabrowser.org/oma/group/A0A8V1AJM9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LIY2-1", "protein_name": "Inositol polyphosphate 5-phosphatase K", "gene_name": "INPP5K", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAATNPQTEPRSRTLSIHVVTWNVASAAPPPDLSDLLQLHTPNLNLDVYVIGLQEMNCGIMSLLSDTAFEDPWSSFFMDVLSPLSFVKVSSVRMQGLLLLVFAKYQHLPFIQILSAKSTPTGLFGYWGNKGGVNIFLKLYGYYVSIINCHLPPHMANNDQRLEHFDRILEMQNFEAQDIPNILDHDLILWFGDMNFRIEDFGLHFVRESIKHQCYSDLWEKDQLSIAKRHDPLLREFQEGPLLFPPTYKFDKNSNNYDTSEKKRKPAWTDRILWRLKRQPQADCHPPTLPGPHFSLVLRSYVSHMMYSISDHKPVTGTFDLELKPLVSAPLITLLPEGPCTTESDLLISYSLASDFLSSPWDWIGLYKVGLRHINDYVSYVWVGDNQVSFGDQLNQVYISLSDIPETEDGFLLFYYSNSLRSVVGISRPFKIQPRSFLEQDSLDEAQPQI", "length": 450 }, "evidence": [ { "id": "A0A8V1AJM9", "url": "https://omabrowser.org/oma/group/A0A8V1AJM9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5EAF2-1", "protein_name": "Type IV inositol polyphosphate 5-phosphatase 11", "gene_name": "IP5P11", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": 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automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506307" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106433", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN8", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997431.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997431" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN9", "locus": { "chromosome": "18", "start_pos": 10507554, "end_pos": 10500929, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029342", "url": "https://www.ensembl.org/id/ENSGALG00010029342" } ] } } ], "crossref": [ { "id": "A0A8V1AJN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "422089", 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"synonym", "evidence": [ { "id": "NP_001001310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001310" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01009972.1, BX934148.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992531 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. On Sep 23, 2021 this sequence version replaced NP_001001310.2. Sequence Note:This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001001310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001310" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC408038", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJQ2", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "408038", "url": "https://www.ncbi.nlm.nih.gov/gene/408038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003461", "url": 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gallus OX=9031 GN=TLCD2 PE=4 SV=1 CANONICAL=A0A8V1AJR3-1" }, "locus": { "chromosome": "19", "start_pos": 5852561, "end_pos": 5849725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070991.1", "url": "https://www.ensembl.org/id/ENSGALT00010070991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043682.1", "url": "https://www.ensembl.org/id/ENSGALP00010043682.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR3" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR3" } ], "pmid": "" }, { "name": "membrane assembly", "id": "GO:0071709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR3" } ], "pmid": "" }, { "name": "regulation of membrane lipid distribution", "id": "GO:0097035", 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJR4-1", "uniprot_ac": "A0A8V1AJR4", "uniprot_id": "A0A8V1AJR4_CHICK", "mass": { "chemical_mass": 58220.0, "monoisotopic_mass": 58220.0 }, "refseq": {}, "gene_names": [ { "name": "PLIN5", "type": "recommended", "evidence": [ { "id": "A0A8V1AJR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR4" } ] } ], "protein_names": [ { "name": "Perilipin 5", "type": "synonym", "evidence": [ { "id": "A0A8V1AJR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, 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"MSHGTPWTPWGRRGPPPPLQRPLEDGGSPAPPPPPQGPSPRRDLSHADPPVRTPRTCPPRGAGTQPRLQRGSPRGPPRGTPRCPAPLPPLADPTPVHPGGVGAMSANNAAPAREELQQSVVVRVANLPLVSSACSTVSSAYNSTKGSHPYVRSVCDAAEKGVRTLTAAAVSGAQPILTKLEPQISTANEYACKGLDKLEEKLPILQQPTEKVVAGTKELVLCTVMGVREAVSGAVGMAYGAVRGGVERTQRMLSCSIGTVVGTRLGQLLANGTDTVLEKSEELMGHYLPGMDGGPAGGTGVTSREQRRRRQSCMVRVGSLSAKLKHRALRRSLGELRWAQHSAQQALSGLHRIIELVEQGSLHSARQHLHRMWLEWSLQDDAPMEDHQVEVRTMAMLRGLLRQLRAACAHLPIRGLPRGVQDTVGHVRHGVEGLHSSLSRARSFHDLSGMVLEQSRQRVLQAQLSIDELLEYVGQHAALPWIVGPFAPVLVEYPEDCPIEMAKWDGCVCVGHGVSAEPNGCAEGSQPQWGQQQDGLGGPAWDP", "length": 543, "header": "tr|A0A8V1AJR4-1|A0A8V1AJR4_CHICK Isoform 1 of Perilipin 5 OS=Gallus gallus OX=9031 GN=PLIN5 PE=3 SV=1 CANONICAL=A0A8V1AJR4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR4/entry#A0A8V1AJR4-1", "sequence": { "sequence": "MSHGTPWTPWGRRGPPPPLQRPLEDGGSPAPPPPPQGPSPRRDLSHADPPVRTPRTCPPRGAGTQPRLQRGSPRGPPRGTPRCPAPLPPLADPTPVHPGGVGAMSANNAAPAREELQQSVVVRVANLPLVSSACSTVSSAYNSTKGSHPYVRSVCDAAEKGVRTLTAAAVSGAQPILTKLEPQISTANEYACKGLDKLEEKLPILQQPTEKVVAGTKELVLCTVMGVREAVSGAVGMAYGAVRGGVERTQRMLSCSIGTVVGTRLGQLLANGTDTVLEKSEELMGHYLPGMDGGPAGGTGVTSREQRRRRQSCMVRVGSLSAKLKHRALRRSLGELRWAQHSAQQALSGLHRIIELVEQGSLHSARQHLHRMWLEWSLQDDAPMEDHQVEVRTMAMLRGLLRQLRAACAHLPIRGLPRGVQDTVGHVRHGVEGLHSSLSRARSFHDLSGMVLEQSRQRVLQAQLSIDELLEYVGQHAALPWIVGPFAPVLVEYPEDCPIEMAKWDGCVCVGHGVSAEPNGCAEGSQPQWGQQQDGLGGPAWDP", "length": 543, "header": "tr|A0A8V1AJR4-1|A0A8V1AJR4_CHICK Isoform 1 of Perilipin 5 OS=Gallus gallus OX=9031 GN=PLIN5 PE=3 SV=1 CANONICAL=A0A8V1AJR4-1" }, "locus": { "chromosome": "28", "start_pos": 2981519, "end_pos": 2978838, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069539.1", "url": "https://www.ensembl.org/id/ENSGALT00010069539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042800.1", "url": 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"A0A8V1AJR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR4" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU3/entry#names_and_taxonomy" } ] }, { "name": "epidermal differentiation protein starting with MTF motif 3", "type": "synonym", "evidence": [ { "id": "NP_001338382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338382" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738215, SAMN02738216 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000349.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001338382", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001338382" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107055126", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU3", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055126", "url": "https://www.ncbi.nlm.nih.gov/gene/107055126", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "gga:107055126", "url": 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G exchanging factor-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AJW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion. Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2#function" }, { "database": "UniProtKB", "id": "ARBA00059435", "url": "https://www.uniprot.org/uniprotkb/ARBA00059435#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RCC1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2", "locus": { "chromosome": "19", "start_pos": 3122681, "end_pos": 3137608, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029374", "url": "https://www.ensembl.org/id/ENSGALG00010029374" } ] } } ], "crossref": [ { "id": "A0A8V1AJW2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJW2", "url": "https://www.orthodb.org/?gene=A0A8V1AJW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46337:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46337:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AJW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGSHERGLAKPAGPPSARQLREADEASPIFQYVGKAVKRKDRVFVWGFSYSGALGVPSFVKPDAGWKKPRRIQATPYRLETEEKITSAACGYGFTLLSSNTTDITKVWGMGLNKDSQLGFQRSIRDRTKGYEYVLEPSPIPLPLEKPQKTRVLQVSCGRAHSLVLTDSEGVFTMGNNSYGQCGRKVVEDEIYSESHLIHQLNDFDSRVVQVVCGQDHSLFRTKKGAVFACGWGADGQTGLGHYNITSVPTKLGGDIAGVNIVQVSSYGDCCLAVSDEGDLFGWGNSEYLQLASVTETTQVNVPRHLPFKIGKIKEAACGGTGNIVLTEEGAVFVWGYGILGKGPNLTETAVPEMIPPSLFGWSDFSSDVRVARVRCGLSHFAALTNRGELFVWGKNLRGCLGIGRMEDQYFPWRVTIPGEVVDVACGVDHMVSMVKSFM", "length": 440, "header": "tr|A0A8V1AJW2-1|A0A8V1AJW2_CHICK Isoform 1 of RCC1-like G exchanging factor-like protein OS=Gallus gallus OX=9031 GN=RCC1L PE=4 SV=1 CANONICAL=A0A8V1AJW2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2/entry#A0A8V1AJW2-1", "sequence": { "sequence": "MRGSHERGLAKPAGPPSARQLREADEASPIFQYVGKAVKRKDRVFVWGFSYSGALGVPSFVKPDAGWKKPRRIQATPYRLETEEKITSAACGYGFTLLSSNTTDITKVWGMGLNKDSQLGFQRSIRDRTKGYEYVLEPSPIPLPLEKPQKTRVLQVSCGRAHSLVLTDSEGVFTMGNNSYGQCGRKVVEDEIYSESHLIHQLNDFDSRVVQVVCGQDHSLFRTKKGAVFACGWGADGQTGLGHYNITSVPTKLGGDIAGVNIVQVSSYGDCCLAVSDEGDLFGWGNSEYLQLASVTETTQVNVPRHLPFKIGKIKEAACGGTGNIVLTEEGAVFVWGYGILGKGPNLTETAVPEMIPPSLFGWSDFSSDVRVARVRCGLSHFAALTNRGELFVWGKNLRGCLGIGRMEDQYFPWRVTIPGEVVDVACGVDHMVSMVKSFM", "length": 440, "header": "tr|A0A8V1AJW2-1|A0A8V1AJW2_CHICK Isoform 1 of RCC1-like G exchanging factor-like protein OS=Gallus gallus OX=9031 GN=RCC1L PE=4 SV=1 CANONICAL=A0A8V1AJW2-1" }, "locus": { "chromosome": "19", "start_pos": 3137409, "end_pos": 3124672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071043.1", "url": "https://www.ensembl.org/id/ENSGALT00010071043.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043734.1", "url": "https://www.ensembl.org/id/ENSGALP00010043734.1" } ] } } ], 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW2" }, { "id": "PF25390", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RCC1-like", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 321, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 245, "end_pos": 247 }, { "start_pos": 346, "end_pos": 348 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJW6-1", "uniprot_ac": "A0A8V1AJW6", "uniprot_id": "A0A8V1AJW6_CHICK", "mass": { "chemical_mass": 27857.0, "monoisotopic_mass": 27857.0 }, "refseq": { "ac": "XP_015150779", "name": "matrix-remodeling-associated protein 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150779" }, "gene_names": [ { "name": "MXRA7", "type": "recommended", "evidence": [ { "id": "A0A8V1AJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6" } ] }, { "name": "MXRA7", "type": "synonym", "evidence": [ { "id": "XP_015150779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150779" } ] } ], "protein_names": [ { "name": "Matrix remodeling associated 7", "type": "synonym", "evidence": [ { "id": "A0A8V1AJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6/entry#names_and_taxonomy" } ] }, { "name": "matrix-remodeling-associated protein 7", "type": "synonym", "evidence": [ { "id": "XP_015150779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150779" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015150779.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150779" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MXRA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJW6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "769894", "url": "https://www.ncbi.nlm.nih.gov/gene/769894", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769894", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769894", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMNIPRQ", "url": "https://omabrowser.org/oma/group/EMNIPRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJW6", "url": "https://www.orthodb.org/?gene=A0A8V1AJW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21845:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21845:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25473", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25473", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150779", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVAVDLYLAVPLLFTVLAIVLASVFVKLRGGEGQRAAERQPESEPEPSKAEPGREEPGSAAGGEAEPRGAAEGPGVEGSRVPVEEVGAGGEGKEEEKEKEEQEKEAAVAEQKSAAEQKPVAERSPESIPRPPPAAEPREQQQQQQQQQEDEEEEEEESKEEDPDSDSEKLMVKETEDDDAADETFSFKYSPGKLRGNQYKSMMTKEELEEEQRVQREQLAAIFRLMKEKSDTFGEMSEGDMKEQLKLYDI", "length": 251, "header": "tr|A0A8V1AJW6-1|A0A8V1AJW6_CHICK Isoform 1 of Matrix remodeling associated 7 OS=Gallus gallus OX=9031 GN=MXRA7 PE=1 SV=1 CANONICAL=A0A8V1AJW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6/entry#A0A8V1AJW6-1", "sequence": { "sequence": "MDVAVDLYLAVPLLFTVLAIVLASVFVKLRGGEGQRAAERQPESEPEPSKAEPGREEPGSAAGGEAEPRGAAEGPGVEGSRVPVEEVGAGGEGKEEEKEKEEQEKEAAVAEQKSAAEQKPVAERSPESIPRPPPAAEPREQQQQQQQQQEDEEEEEEESKEEDPDSDSEKLMVKETEDDDAADETFSFKYSPGKLRGNQYKSMMTKEELEEEQRVQREQLAAIFRLMKEKSDTFGEMSEGDMKEQLKLYDI", "length": 251, "header": "tr|A0A8V1AJW6-1|A0A8V1AJW6_CHICK Isoform 1 of Matrix remodeling associated 7 OS=Gallus gallus OX=9031 GN=MXRA7 PE=1 SV=1 CANONICAL=A0A8V1AJW6-1" }, "locus": { "chromosome": "18", "start_pos": 4906315, "end_pos": 4886210, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071048.1", "url": "https://www.ensembl.org/id/ENSGALT00010071048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043739.1", "url": "https://www.ensembl.org/id/ENSGALP00010043739.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769894", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769894", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW6" }, { "id": "PF25473", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25473" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Matrix-remodeling-associated protein 7 helical", "eco_id": "ECO_0000259", "start_pos": 189, "end_pos": 250, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJW7-1", "uniprot_ac": "A0A8V1AJW7", "uniprot_id": "A0A8V1AJW7_CHICK", "mass": { "chemical_mass": 24823.0, "monoisotopic_mass": 24823.0 }, "refseq": { "ac": "XP_025010451", "name": "coiled-coil domain-containing glutamate-rich protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010451" }, "gene_names": [ { "name": "LOC112533358", "type": "recommended", "evidence": [ { "id": "A0A8V1AJW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW7" } ] }, { "name": "LOC112533358", "type": "synonym", "evidence": [ { "id": "XP_025010451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010451" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AJW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW7/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing glutamate-rich protein 1-like", "type": "synonym", "evidence": [ { "id": "XP_025010451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010451" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025010451.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025010451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010451" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112533358", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJW7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJW7", "database": "AlphaFoldDB", "categories": [] }, { "id": "112533358", "url": "https://www.ncbi.nlm.nih.gov/gene/112533358", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:112533358", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112533358", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEMDPLD", "url": "https://omabrowser.org/oma/group/CEMDPLD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJW7", "url": "https://www.orthodb.org/?gene=A0A8V1AJW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15482", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15482", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025010451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025010451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRAEPAAWSGARRPRWAPARGEGLPGGGCAPLKGEARRGGSRSRWPPGRRGGQPGVWRKLLGSRTHSHLQHSLQLQQRCRAVRRCHRPYRPRVLLSLRPVNLLGRRAPGMRAPRNTNQFLMREKYQLMHLRSDSVGTESGGSDCEMDPLDMDSYLGVLENARGALTGPAEDAPPRPAEPPPAAPLLAQEDSQQYFPSEDDVLESELFMERDFLEFCSRIA", "length": 222, "header": "tr|A0A8V1AJW7-1|A0A8V1AJW7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC112533358 PE=4 SV=1 CANONICAL=A0A8V1AJW7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW7/entry#A0A8V1AJW7-1", "sequence": { "sequence": "MLRRAEPAAWSGARRPRWAPARGEGLPGGGCAPLKGEARRGGSRSRWPPGRRGGQPGVWRKLLGSRTHSHLQHSLQLQQRCRAVRRCHRPYRPRVLLSLRPVNLLGRRAPGMRAPRNTNQFLMREKYQLMHLRSDSVGTESGGSDCEMDPLDMDSYLGVLENARGALTGPAEDAPPRPAEPPPAAPLLAQEDSQQYFPSEDDVLESELFMERDFLEFCSRIA", "length": 222, "header": "tr|A0A8V1AJW7-1|A0A8V1AJW7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC112533358 PE=4 SV=1 CANONICAL=A0A8V1AJW7-1" }, "locus": { "chromosome": "12", "start_pos": 3693346, "end_pos": 3692681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068349.1", "url": "https://www.ensembl.org/id/ENSGALT00010068349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042092.1", "url": "https://www.ensembl.org/id/ENSGALP00010042092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:112533358", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112533358", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJW8-1", "uniprot_ac": "A0A8V1AJW8", "uniprot_id": "A0A8V1AJW8_CHICK", "mass": { "chemical_mass": 89471.0, "monoisotopic_mass": 89471.0 }, "refseq": { "ac": "XP_040542685", "name": "protein HID1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542685" }, "gene_names": [ { "name": "HID1", "type": "recommended", "evidence": [ { "id": "A0A8V1AJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ] }, { "name": "HID1", "type": "synonym", "evidence": [ { "id": "XP_040542685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542685" } ] } ], "protein_names": [ { "name": "HID1 domain containing", "type": "synonym", "evidence": [ { "id": "A0A8V1AJW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8/entry#names_and_taxonomy" } ] }, { "name": "protein HID1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040542685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542685" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052590.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040542685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542685" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8", "locus": { "chromosome": "18", "start_pos": 11125650, "end_pos": 11227146, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029669", "url": "https://www.ensembl.org/id/ENSGALG00010029669" } ] } } ], "crossref": [ { "id": "A0A8V1AJW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "422113", "url": "https://www.ncbi.nlm.nih.gov/gene/422113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IFEDDKW", "url": "https://omabrowser.org/oma/group/IFEDDKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEJ4", "url": "https://www.orthodb.org/?gene=A0A8V1AEJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJW8", "url": "https://www.orthodb.org/?gene=A0A8V1AJW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALK6", "url": "https://www.orthodb.org/?gene=A0A8V1ALK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APQ9", "url": "https://www.orthodb.org/?gene=A0A8V1APQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21575", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21575", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21575:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21575:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040542685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040542685", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHTEKERQIVLNCSRLLTRILPYIFEDPDWRGFFWSTVPGAGRGGGDEDDENARPLAESLLLAVADLLFCPDFTVQSHRRSTVDTAEDIHSIDSCEYIWEAGVGFAHSPQPNYIHDLNRTELLKLLLTCFSEAMYLPPSSDSSNTNPWVQFFCSTENRHALPLFTSLLNVVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDYDSSTSSSPTVDGTTTGTAMDDVDPPGPDNLFVNYLSRIHREEDFQFILKGVARLLSNPLVQTYLPNSAKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIIVFHKIITSGHQRLQPLFDCLLTIIVNVSPYLKSLSMVAANKLLHLLEAFSTTWFLFSAVQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAVIRKRNVFHQLANLPTDSQSIQKGLQRKKKSPEPISRTNSQDGASMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTMRSLEPESLQPLPEGNLPSAASDGEPWSGEVSHPQRDRRRLSSASSSGQWSPTPDWVMSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 796, "header": "tr|A0A8V1AJW8-1|A0A8V1AJW8_CHICK Isoform 1 of HID1 domain containing OS=Gallus gallus OX=9031 GN=HID1 PE=1 SV=1 CANONICAL=A0A8V1AJW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8/entry#A0A8V1AEJ4-1", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHTEKERQIVLNCSRLLTRILPYIFEDPDWRGFFWSTVPGAGRGGGDEDDENARPLAESLLLAVADLLFCPDFTVQSHRRSTVDTAEDIHSIDSCEYIWEAGVGFAHSPQPNYIHDLNRTELLKLLLTCFSEAMYLPPSSDSSNTNPWVQFFCSTENRHALPLFTSLLNVVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDYDSSTSSSPTVDGTTTGTAMDDVDPPGPDNLFVNYLSRIHREEDFQFILKGVARLLSNPLVQTYLPNSAKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIIVFHKIITSGHQRLQPLFDCLLTIIVNVSPYLKSLSMVAANKLLHLLEAFSTTWFLFSAVQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAVIRKRNVFHQLANLPTDSQSIQKGLQRKKKSPEPISRTNSQDGASMEGSRPAAPAEPGTLKTSLVATPGGQWSPTPDWVMSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 734, "header": "tr|A0A8V1AEJ4-1|A0A8V1AEJ4_CHICK Computationally mapped isoform of HID1 domain containing OS=Gallus gallus OX=9031 GN=HID1 PE=1 SV=1 CANONICAL=A0A8V1AJW8-1" }, "locus": { "chromosome": "18", "start_pos": 11227030, "end_pos": 11205076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071756.1", "url": "https://www.ensembl.org/id/ENSGALT00010071756.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044446.1", "url": "https://www.ensembl.org/id/ENSGALP00010044446.1" } ] } }, { "isoform_ac": "A0A8V1AJW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8/entry#A0A8V1AJW8-1", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHTEKERQIVLNCSRLLTRILPYIFEDPDWRGFFWSTVPGAGRGGGDEDDENARPLAESLLLAVADLLFCPDFTVQSHRRSTVDTAEDIHSIDSCEYIWEAGVGFAHSPQPNYIHDLNRTELLKLLLTCFSEAMYLPPSSDSSNTNPWVQFFCSTENRHALPLFTSLLNVVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDYDSSTSSSPTVDGTTTGTAMDDVDPPGPDNLFVNYLSRIHREEDFQFILKGVARLLSNPLVQTYLPNSAKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIIVFHKIITSGHQRLQPLFDCLLTIIVNVSPYLKSLSMVAANKLLHLLEAFSTTWFLFSAVQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAVIRKRNVFHQLANLPTDSQSIQKGLQRKKKSPEPISRTNSQDGASMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTMRSLEPESLQPLPEGNLPSAASDGEPWSGEVSHPQRDRRRLSSASSSGQWSPTPDWVMSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 796, "header": "tr|A0A8V1AJW8-1|A0A8V1AJW8_CHICK Isoform 1 of HID1 domain containing OS=Gallus gallus OX=9031 GN=HID1 PE=1 SV=1 CANONICAL=A0A8V1AJW8-1" }, "locus": { "chromosome": "18", "start_pos": 11227030, "end_pos": 11205076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071758.1", "url": "https://www.ensembl.org/id/ENSGALT00010071758.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044448.1", "url": "https://www.ensembl.org/id/ENSGALP00010044448.1" } ] } }, { "isoform_ac": "A0A8V1ALK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8/entry#A0A8V1ALK6-1", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHTEKERQIVLNCSRLLTRILPYIFEDPDWRGFFWSTVPGAGRGGGDEDDENARPLAESLLLAVADLLFCPDFTVQSHRRSTVDTAEDIHSIDSCEYIWEAGVGFAHSPQPNYIHDLNRTELLKLLLTCFSEAMYLPPSSDSSNTNPWVQFFCSTENRHALPLFTSLLNVVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDYDSSTSSSPTVDGTTTGTAMDDVDPPGPDNLFVNYLSRIHRDFQFILKGVARLLSNPLVQTYLPNSAKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIIVFHKIITSGHQRLQPLFDCLLTIIVNVSPYLKSLSMVAANKLLHLLEAFSTTWFLFSAVQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAVIRKRNVFHQLANLPTDSQSIQKGLQRKKKSPEPISRTNSQDGASMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTMRSLEPESLQPLPEGNLPSAASDGEPWSGEVSHPQRDRRRLSSASSSGQWSPTPDWVMSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 794, "header": "tr|A0A8V1ALK6-1|A0A8V1ALK6_CHICK Computationally mapped isoform of HID1 domain containing OS=Gallus gallus OX=9031 GN=HID1 PE=1 SV=1 CANONICAL=A0A8V1AJW8-1" }, "locus": { "chromosome": "18", "start_pos": 11227030, "end_pos": 11205076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071755.1", "url": "https://www.ensembl.org/id/ENSGALT00010071755.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044445.1", "url": "https://www.ensembl.org/id/ENSGALP00010044445.1" } ] } }, { "isoform_ac": "A0A8V1APQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8/entry#A0A8V1APQ9-1", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKGDEDDENARPLAESLLLAVADLLFCPDFTVQSHRRSTVDTAEDIHSIDSCEYIWEAGVGFAHSPQPNYIHDLNRTELLKLLLTCFSEAMYLPPSSDSSNTNPWVQFFCSTENRHALPLFTSLLNVVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDYDSSTSSSPTVDGTTTGTAMDDVDPPGPDNLFVNYLSRIHREEDFQFILKGVARLLSNPLVQTYLPNSAKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIIVFHKIITSGHQRLQPLFDCLLTIIVNVSPYLKSLSMVAANKLLHLLEAFSTTWFLFSAVQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAVIRKRNVFHQLANLPTDSQSIQKGLQRKKKSPEPISRTNSQDGASMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTMRSLEPESLQPLPEGNLPSAASDGEPWSGEVSHPQRDRRRLSSASSSGQWSPTPDWVMSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 739, "header": "tr|A0A8V1APQ9-1|A0A8V1APQ9_CHICK Computationally mapped isoform of HID1 domain containing OS=Gallus gallus OX=9031 GN=HID1 PE=1 SV=1 CANONICAL=A0A8V1AJW8-1" }, "locus": { "chromosome": "18", "start_pos": 11227030, "end_pos": 11205076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071757.1", "url": "https://www.ensembl.org/id/ENSGALT00010071757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044447.1", "url": "https://www.ensembl.org/id/ENSGALP00010044447.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 619, "start_aa": "Thr", "end_pos": 619, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr619", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 689, "start_aa": "Thr", "end_pos": 689, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr689", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287BQ79-1", "protein_name": "HID1 domain containing", "gene_name": "HID1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHSEKEKQIVLNCSRLLTRVLPCIFEDPDWRGFFWSTVPGAGRGGQGEDDDENARPLAESLLLAIADLLFCPDFTVQSHRRSTVDSAEDIHSLDSCEYIWEAGVGFAHSPQPSYIHDMNRMELLKLLLTCFSEAMYLPPAADCGNTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSTTSASPTVDGTTTGTAMDDADPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVAANKLLHLLEAFSTTWFLFSAAQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRSVFHQLANLPTDPPAIHKALQRRRRAPEPLSRTGSQEGASMEGSRPAVPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPAPQQSSAEGSPATEEPSQAWREQRRPSSASASGQWSPTSEWVLSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPVWYDTDVKLFEIQRV", "length": 788 }, "evidence": [ { "id": "A0A8V1AJW8", "url": "https://omabrowser.org/oma/group/A0A8V1AJW8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7GBX3-1", "protein_name": "Protein HID1 isoform X1", "gene_name": "Hid1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHSEKERQVVLNCSRLLTRVLPYIFEDPDWRGFFWSTVPGAGRGGQGEEDDETARPLAESLLLAIADLLFCPDFTVQSHRRNNVDSAEDVRSLDSCEYIWEAGVGFAHSPQPNSIHDMNRMELLKLLLTCFSEAMYLPPSPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSATSTTCTVDGTTTGTAMDDAEPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIVVFHKIVTSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSASQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRGVFHQLANLPTDPPSIHKALQRRRKTPEPLSRAGSQEGASMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPESQSSSAEGSPSEGEPSQTWREQRRLSSASASGQWNPTSDWILSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQANSGTAVWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 788 }, "evidence": [ { "id": "A0A8V1AJW8", "url": "https://omabrowser.org/oma/group/A0A8V1AJW8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A0C3-1", "protein_name": "Protein HID1", "gene_name": "Hid1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDNAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAEGGCHSEKEKQVVLNCSRLLTRVLPYIFEDPDWRGFFWSTVPGAGRGGQGEEEDENARPLAESLLLAIADLLFCPDFTVQNHRRNDVDSAEDVHSLDSCEYIWEAGVGFAHSPQPNYIHDMNRMELLKLLLTCFSEAMYLPPSPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSATSTSPTVDGTTTGTVMDDADPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSASQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRGVFHQLANLPTDPPSIHKALQRRRRTPEPLSRAGSQEGASMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPESQQNSAEGSPSEGEPNQTWREQRRLSNASASGQWSPTSDWILSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 788 }, "evidence": [ { "id": "A0A8V1AJW8", "url": "https://omabrowser.org/oma/group/A0A8V1AJW8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0E9B5-1", "protein_name": "Protein HID1", "gene_name": "Dmc1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNTDSKLNFRKAIVQLTQKNQKIDPSDEQFWEQFWQGHQTTLEDVFALVTSSEIRQIRNENPANLATLCYKAVEKLAQAVDSSCRTQAEQQCVLNCVRLLVRCLPYIFEDEKWRDFFWSSLPSQDKTMPLAQSLLNATCDLLFCPDFTVTATRRAGPEKAEELANIDSCEYIWEAGVGFAQSPPHNAHMERRRTELLKLLLTCFSEPMYRSPQQSEEPNKWIAYFTSADNRHALPLFTSFLNTVCSYDPVGFGVPYNHLLFADTTEPLVEACLQLLIVTLDHDMVVQQQLTQPGQASYDEGNCGDNLFINYLSRVHRDEDFHFVLKGITRLLNNPLVQNYLPNSTKRLHCHQELLILFWKICDYNKKFLYFVLKSSDVLDILIPILYHLNYSRADQSRVGLMHIGVFILLLLSGERNFGVRLNKAYSATVPMDIPVFTGTHADLLITVFHKIIATGHQRLQPLFDCLLTILVNVSPYLKTLSMVASVKMLHLLEAFSTPWFLLSAPSNHHLVFFLLEIFNNIIQYQFDGNSNLVYTIIRKRHVFHAMANLPTDMAGIAKCLSGRKTGGKFNLPRVPQRRTPAVSQELPSAHVPEEYNEEDEDEDEEEIINEEPKAEEDLESETESHERSQAGELQSDVLTAQPAEPGTLKTSLLDTPGITQMTEREQAHPNDKPQVEDSTDIVPYDRSAASTPTDERKSTSPTELSRLSVAHRASIRMVPGESDRWTPTPEWIVSWRSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILKFLQHGTLVGLLPVPHPILIRKYQANAGTTAWFRTYIWGVIYLRNVEPAIWYDTEVKLFEIQRV", "length": 837 }, "evidence": [ { "id": "A0A8V1AJW8", "url": "https://omabrowser.org/oma/group/A0A8V1AJW8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q54JJ6-1", "protein_name": "Protein HID1", "gene_name": "hid1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGTGSSREQHLNSFNTLQKETVPFSSDLWKTILSQNLEDDSLYLENLKKLKNERPENLATFIKKLVNQLVLVKGLQRETNTPGDFQLTSISLSYLSRILPIVFESGDDFADKVFWLNEGIEPLSHPSAKISTPPSITTTKTTEIIEEQEKKDQENKQVEENKENEEKKDEEKKDEEKKDEEKKDEDKKENKTTTTTTTTNTTNNTNNNNNSDESSFDTTPLAVKLMDSLLDLLFFPGFTVTESLGLKSPKEASPDAIPVLFSWAGGFGVDSVPTVHNKQFWINRLSVLQCLITCLSEQLYVPQDSVSTFKSKWLDWITHTQEYYTEALLFSLINTFATFDPIGWGIPYNHLMYSDDHEICSKLSIQILNVLLTYDPIENNDQQPQQQHHHHQQQHHQQQQQQQQSTIECRNKFIQYIKTLKRVRDFKFFFNAFERIMNVPLIASHTKLPNSTKKIELHQDLTYTMWLFLSYNHDFLRSIVNYENSPEFLIPLLQYMDEGRKSQTTHGIVQIGTFILLLLSGERDFSISLNKPFVGRIHIDIQQPQVYSDFVITVMYRLLVDTPDRLESIYECVLTILSNLSPYMKNLSMVTCVKLMKLFEYLSTPRFLFATNHNYRYVGFLLESLNNLLQHQYESNTRLIYAILRCQNQFSKLAYLKISPVTPSKPMEQITQPSPISTSEEAFGKLNKLSISEEPSTLSNEKSDKTTDGGDHQDESISKSKVQSKPTTEHPNSTGATPSSTNSGTPTIKAFSSTTPNQESPKLGGDGIDSQSSTPNKQQLPPPPPQQTKKTQMVSHFMPTDEWLQDIKKQLPLDNILKVITHLSPQIQGLCTGSGSDEQKIMDYLKMSTIVGIFHNPGPIMTRRYHSNAITKSWFIAYMWCIIYLENHSPPLFLHTNIKLFQVKQ", "length": 905 }, "evidence": [ { "id": "A0A8V1AJW8", "url": "https://omabrowser.org/oma/group/A0A8V1AJW8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IV36-1", "protein_name": "Protein HID1", "gene_name": "HID1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSTDSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHSEKEKQIVLNCSRLLTRVLPYIFEDPDWRGFFWSTVPGAGRGGQGEEDDEHARPLAESLLLAIADLLFCPDFTVQSHRRSTVDSAEDVHSLDSCEYIWEAGVGFAHSPQPNYIHDMNRMELLKLLLTCFSEAMYLPPAPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSASSASPTVDGTTTGTAMDDADPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILFFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSIRVPMDIPVFTGTHADLLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSAAQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRSIFHQLANLPTDPPTIHKALQRRRRTPEPLSRTGSQEGTSMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPEPQQSLEDGSPAKGEPSQAWREQRRPSTSSASGQWSPTPEWVLSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPVWYDTDVKLFEIQRV", "length": 788 }, "evidence": [ { "id": "A0A8V1AJW8", "url": "https://omabrowser.org/oma/group/A0A8V1AJW8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R1F6-1", "protein_name": "Protein HID1", "gene_name": "Hid1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSADSKLNFRKAVIQLTTKTQPVEATDNAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAEGGCHSEKEKQVVLNCSRLLTRVLPYIFEDPDWRGFFWSTVPGAGRGGQGEEEDENARPLAESLLLAIADLLFCPDFTVQNHRRNDVDSAEDVHSLDSCEYIWEAGVGFAHSPQPNYIHDMNRMELLKLLLTCFSEAMYLPPSPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSATSTSPTVDGTTTGTAMDDADPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSVRVPMDIPVFTGTHADLLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSASQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRAVFHQLANLPTDPPSIHKALQRRRRTPEPLSRTGSQEGTSMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPESQQSSAENSPSDGESSQTWREQRRLSNASASGQWSPTSDWILSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPIWYDTDVKLFEIQRV", "length": 788 }, "evidence": [ { "id": "A0A8V1AJW8", "url": "https://omabrowser.org/oma/group/A0A8V1AJW8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ], "pmid": "" }, { "name": "Golgi medial cisterna", "id": "GO:0005797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005797", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ], "pmid": "" }, { "name": "Golgi trans cisterna", "id": "GO:0000138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ], "pmid": "" }, { "name": "cytoplasmic side of Golgi membrane", "id": "GO:0098548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"isoform_ac": "A0A8V1AJZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2/entry#A0A8V1AJZ2-1", "sequence": { "sequence": "MNDQYHRAARDGYLDLLKEATKKDLNSPDEDGMTPTLWAAYHGNLDALRLIVSRGGDPDKCDIWGNTPLHLAAANGHLNCLSFLISFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVSKLKDKAFRDAERRIKDCVKLQKKHHERMEKRYRKEMSDNSDTMSFSSYSSSTLSKKFQHMSMVTSLPYSQATIHGTAKGKTKIQRKLERKKQVDGTFKIYEDGRKSVRSLSGLQLGNDVMFVKQGTYASPKEWTRRNIRDMFLTDEDTVSRAISDPGLHMDSAHSEVSTDSGHESLFKPPRVGHHGVPAQLRQQRALRDRPRGRRRVGGGQRGRGRAQTARPPAALAKSQRQHWQCQQPAGEERGGAALGRGGAGPRRRR", "length": 393, "header": "tr|A0A8V1AJZ2-1|A0A8V1AJZ2_CHICK Isoform 1 of USH1 protein network component sans OS=Gallus gallus OX=9031 GN=USH1G PE=4 SV=1 CANONICAL=A0A8V1AJZ2-1" }, "locus": { "chromosome": "18", "start_pos": 11181243, "end_pos": 11175325, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071783.1", "url": "https://www.ensembl.org/id/ENSGALT00010071783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044473.1", "url": "https://www.ensembl.org/id/ENSGALP00010044473.1" } ] } }, { "isoform_ac": "A0A8V1APS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2/entry#A0A8V1APS2-1", "sequence": { "sequence": "MVFRRNYVSSGLFGIGREDAGVLGEGNADGAGLKLRGRLQRSPSLNDSIGSANSLQERNAEELPWDEVELGLDDDDEPDSSPLETFLASLHMFEFISILKKEKIDLEALMLCSDNDLKSINIPLGPRKKIVDAIQRRRQTLERPDVIVDTEL", "length": 152, "header": "tr|A0A8V1APS2-1|A0A8V1APS2_CHICK Computationally mapped isoform of USH1 protein network component sans OS=Gallus gallus OX=9031 GN=USH1G PE=4 SV=1 CANONICAL=A0A8V1AJZ2-1" }, "locus": { "chromosome": "18", "start_pos": 11175551, "end_pos": 11174381, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071782.1", "url": "https://www.ensembl.org/id/ENSGALT00010071782.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044472.1", "url": "https://www.ensembl.org/id/ENSGALP00010044472.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "regulation of clathrin-dependent endocytosis", "id": "GO:2000369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000369", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "sensory perception of light stimulus", "id": "GO:0050953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" }, { "name": "equilibrioception", "id": "GO:0050957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050957", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AJZ7-1", "uniprot_ac": "A0A8V1AJZ7", "uniprot_id": "A0A8V1AJZ7_CHICK", "mass": { "chemical_mass": 53183.0, "monoisotopic_mass": 53183.0 }, "refseq": { "ac": "XP_040548927", "name": "PHD finger protein 7-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548927" }, "gene_names": [ { "name": "LOC121112228", "type": "recommended", "evidence": [ { "id": "A0A8V1AJZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7" } ] }, { "name": "LOC121112228", "type": "synonym", "evidence": [ { "id": "XP_040548927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548927" } ] } ], "protein_names": [ { "name": "PHD-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AJZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7/entry#names_and_taxonomy" } ] }, { "name": "PHD finger protein 7-like", "type": "synonym", "evidence": [ { "id": "XP_040548927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548927" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040548927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548927" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121112228", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AJZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AJZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16448", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16448", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "121112228", "url": "https://www.ncbi.nlm.nih.gov/gene/121112228", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TYKSYCH", "url": "https://omabrowser.org/oma/group/TYKSYCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJZ7", "url": "https://www.orthodb.org/?gene=A0A8V1AJZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12420", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12420:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26054", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26054", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040548927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040548927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNMSSRKRKSPDSGEQACVLCRRADVNPDICGRTFAESDLCVHEFCLLFANIRFEESAPWEETVGLPVGTIRCRIKQADQKQCFVCGERGAAISCAERGCARSFHLPCAVDGECVTQFFGQHRSFCREHRPRQAVEAAPSQGTDCVICLEPMGDSTSYQTLRCPACKHTWFHRSCVQGQAMNAGTMCFQCPICQDTEQFRAEMSTLGIQIPVRRPSWWDDRTYPSLLRRHGRCDVSTCLYPGGREQEEADGPWQLLLCSSCAAEGTHRRCSYLSNRVNSWECNSCAGVGTASSSNTERAGPSTSSQGALEPPRGSQGLENISSGPSSQAASGLPQRSQLPENSHLPSEPGTRQRTVRPRLPADHEASRHRGSGRTTAPRTSSGSRRSTQQRASRPSADSPVAAPRRGPRQQGTGRVRSRSPLQDRASRSQSRPRRSRGSRQTPRQAARSSTLCSATPVTSRPSRGSPQPGHRRASRQQGRAHT", "length": 484, "header": "tr|A0A8V1AJZ7-1|A0A8V1AJZ7_CHICK Isoform 1 of PHD-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121112228 PE=4 SV=1 CANONICAL=A0A8V1AJZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7/entry#A0A8V1AJZ7-1", "sequence": { "sequence": "MRNMSSRKRKSPDSGEQACVLCRRADVNPDICGRTFAESDLCVHEFCLLFANIRFEESAPWEETVGLPVGTIRCRIKQADQKQCFVCGERGAAISCAERGCARSFHLPCAVDGECVTQFFGQHRSFCREHRPRQAVEAAPSQGTDCVICLEPMGDSTSYQTLRCPACKHTWFHRSCVQGQAMNAGTMCFQCPICQDTEQFRAEMSTLGIQIPVRRPSWWDDRTYPSLLRRHGRCDVSTCLYPGGREQEEADGPWQLLLCSSCAAEGTHRRCSYLSNRVNSWECNSCAGVGTASSSNTERAGPSTSSQGALEPPRGSQGLENISSGPSSQAASGLPQRSQLPENSHLPSEPGTRQRTVRPRLPADHEASRHRGSGRTTAPRTSSGSRRSTQQRASRPSADSPVAAPRRGPRQQGTGRVRSRSPLQDRASRSQSRPRRSRGSRQTPRQAARSSTLCSATPVTSRPSRGSPQPGHRRASRQQGRAHT", "length": 484, "header": "tr|A0A8V1AJZ7-1|A0A8V1AJZ7_CHICK Isoform 1 of PHD-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC121112228 PE=4 SV=1 CANONICAL=A0A8V1AJZ7-1" }, "locus": { "chromosome": "28", "start_pos": 494537, "end_pos": 491542, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068447.1", "url": "https://www.ensembl.org/id/ENSGALT00010068447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042133.1", "url": "https://www.ensembl.org/id/ENSGALP00010042133.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q9VKW2-1", "protein_name": "Pineapple eye protein", "gene_name": "pie", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEDNKELQCLICKYSDTDDLVFGEWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRKCWYCNKIGASLQCDRCRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKRQLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSGYYLRCIWCRSERFRDSIRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGRTYNRLSWVILCCSSCAATSAHLKCLVGALRLPKKRERTDFKCSMCLDVERRIAEGPARTTEETNADGDNQVDGSFYVQKLGPDAATRSLTQTPVFSEEDESERSSNITVIFSQPKSNATSERLSLSPPQEEMIVEIPDSPEASPKTSIDENHSPQPIARRDTSDSPQPIAASEIPDSPQPTAASEIPDLPQTTAINVNPELTQQTALNTIPHSPQPEASFSTQLVSQTFDCPQPQEQAVAKAPNSPSLPKEDPNTLLVLKSGFQCPGEPFFYLVIYEFEHGTCMGECIGTCVLRFKEDDPRIQDTSQAALERVNITPDDVWCRSEDRGIFEHIEKFHEWYRSEGFS", "length": 582 }, "evidence": [ { "id": "A0A8V1AJZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AJZ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W5W9-1", "protein_name": "PHD finger protein 7, isoform C", "gene_name": "Phf7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVQICVLCLSGERDELIFGTVHVEGNMMVHRNCLYLSSNLIQRGEKKLSIMNFLKEDIEAEVNRCRLLKCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQFCDTYNSFCHQHVLVPRNRPVFKNDEECLLCAEDVVAKGERFSVVTCLYAPCCRNGWFHRRCLQRYANSSGYFFKCPLCNNTDVFRRVAYMGIAVLDQDASWETEPDAFAGQYRRDVNCTAALCVAVSGRADTSAMLLYCTSCGANPSHYLCTLKTLQNYVCKVCSAVSPEAVPVAESDSDDAGSMDDSAEAPRPGHLNGDQIQEKLSPSHWDDFGSSDDDAVFQRAFDTKVQSRVVTLSDDQPSTSAGARALADRGTRTFESQGTQTTFLSSVVTSFRSATATATSSTSTSTSTSASTLDNQENTEPSTSNGRRPWRPRYVSPPRHVSDSDDDSDEYDSDEYESKRRQLTPTAAAPSNGRRLLGSISPEPSTPAPRVLRRRTLANRPSSLANMDISCVANRTRHRLSNHMASRKD", "length": 520 }, "evidence": [ { "id": "A0A8V1AJZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AJZ7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7" }, { "id": "PS51805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 131, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AJZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 195, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 }, { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AK00-1", "uniprot_ac": "A0A8V1AK00", "uniprot_id": "A0A8V1AK00_CHICK", "mass": { "chemical_mass": 50087.0, "monoisotopic_mass": 50087.0 }, "refseq": {}, "gene_names": [ { "name": "SERPINF1", "type": "recommended", "evidence": [ { "id": "A0A8V1AK00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00" } ] } ], "protein_names": [ { "name": "Serpin family F member 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AK00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERPINF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00", "locus": { "chromosome": "19", "start_pos": 5899511, "end_pos": 5894676, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029387", "url": "https://www.ensembl.org/id/ENSGALG00010029387" } ] } } ], "crossref": [ { "id": "A0A8V1AK00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AK00", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACQ4", "url": "https://www.orthodb.org/?gene=A0A8V1ACQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK00", "url": "https://www.orthodb.org/?gene=A0A8V1AK00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11461:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11461:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ACQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNACPVLKSSEPRLAEYFKLEEKKTQQRSGSGMQIPAVLLLLGLLTIPSKSQNSPAGQNSPTTDGTVGEVEEEDPFYKTPINKLAAAVSNFGYDLYRQQSSRTATANVLLSPFSLATALSGLSLGAGERTEDVISRALFYDLLNKAEVHNTYKDLLASVTGPEKSLKSASRIIVEKRLRVKSTFHSQLEKSYRMRLRALSGNTQLDLQEINNWVRQQTRGRILRFMKDMPTDVSILLAGAAYFKGTWKTKFDTKRTVLKDFHLDEDRTVQVSMMSDPKAILRYGFDSELNCKIAQLPLTEGVSAMFFLPTKVTQNMTLIEESLTSEFVHDVDRELKTVHAVLSLPKLKLNYEEALGNTVKETRLQSLFTSPDFTKISAKPIKLSHVQHKAILELSEDGEKSTPNPGVNAARLTFPIEYHVDRPFLLVLRDDTTGTLLFIGKILDPRSV", "length": 448, "header": "tr|A0A8V1AK00-1|A0A8V1AK00_CHICK Isoform 1 of Serpin family F member 1 OS=Gallus gallus OX=9031 GN=SERPINF1 PE=1 SV=1 CANONICAL=A0A8V1AK00-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00/entry#A0A8V1ACQ4-1", "sequence": { "sequence": "MQIPAVLLLLGLLTIPSKSQNSPAGQQSSRTATANVLLSPFSLATALSGLSLGAGERTEDVISRALFYDLLNKAEVHNTYKDLLASVTGPEKSLKSASRIIVEKRLRVKSTFHSQLEKSYRMRLRALSGNTQLDLQEINNWVRQQTRGRILRFMKDMPTDVSILLAGAAYFKGTWKTKFDTKRTVLKDFHLDEDRTVQVSMMSDPKAILRYGFDSELNCKIAQLPLTEGVSAMFFLPTKVTQNMTLIEESLTSEFVHDVDRELKTVHAVLSLPKLKLNYEEALGNTVKETRLQSLFTSPDFTKISAKPIKLSHVQHKAILELSEDGEKSTPNPGVNAARLTFPIEYHVDRPFLLVLRDDTTGTLLFIGKILDPRSV", "length": 376, "header": "tr|A0A8V1ACQ4-1|A0A8V1ACQ4_CHICK Computationally mapped isoform of Serpin family F member 1 OS=Gallus gallus OX=9031 GN=SERPINF1 PE=1 SV=1 CANONICAL=A0A8V1AK00-1" }, "locus": { "chromosome": "19", "start_pos": 5899016, "end_pos": 5894961, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071079.1", "url": "https://www.ensembl.org/id/ENSGALT00010071079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043770.1", "url": "https://www.ensembl.org/id/ENSGALP00010043770.1" } ] } }, { "isoform_ac": "A0A8V1AK00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00/entry#A0A8V1AK00-1", "sequence": { "sequence": "MNACPVLKSSEPRLAEYFKLEEKKTQQRSGSGMQIPAVLLLLGLLTIPSKSQNSPAGQNSPTTDGTVGEVEEEDPFYKTPINKLAAAVSNFGYDLYRQQSSRTATANVLLSPFSLATALSGLSLGAGERTEDVISRALFYDLLNKAEVHNTYKDLLASVTGPEKSLKSASRIIVEKRLRVKSTFHSQLEKSYRMRLRALSGNTQLDLQEINNWVRQQTRGRILRFMKDMPTDVSILLAGAAYFKGTWKTKFDTKRTVLKDFHLDEDRTVQVSMMSDPKAILRYGFDSELNCKIAQLPLTEGVSAMFFLPTKVTQNMTLIEESLTSEFVHDVDRELKTVHAVLSLPKLKLNYEEALGNTVKETRLQSLFTSPDFTKISAKPIKLSHVQHKAILELSEDGEKSTPNPGVNAARLTFPIEYHVDRPFLLVLRDDTTGTLLFIGKILDPRSV", "length": 448, "header": "tr|A0A8V1AK00-1|A0A8V1AK00_CHICK Isoform 1 of Serpin family F member 1 OS=Gallus gallus OX=9031 GN=SERPINF1 PE=1 SV=1 CANONICAL=A0A8V1AK00-1" }, "locus": { "chromosome": "19", "start_pos": 5899016, "end_pos": 5894727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071078.1", "url": "https://www.ensembl.org/id/ENSGALT00010071078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043769.1", "url": "https://www.ensembl.org/id/ENSGALP00010043769.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of angiogenesis", "id": "GO:0016525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00" } ], "pmid": "" }, { "name": "positive regulation of neurogenesis", "id": "GO:0050769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AK00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK00" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 445, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 315, "end_pos": 317 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040509524.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040509524", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040509524" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK09", "locus": {} } ], "crossref": [ { "id": "107055329", "url": "https://www.ncbi.nlm.nih.gov/gene/107055329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004028", "url": 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Classification" ] }, { "id": "QYTLWKE", "url": "https://omabrowser.org/oma/group/QYTLWKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK09", "url": "https://www.orthodb.org/?gene=A0A8V1AK09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR40389", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40389", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR40389:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40389:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02813", "url": 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"MEHVPKVLLQFCKEYCEKNAPSKKNIQAVISRLEREGEIKAPQEVFDHRRWDHLTSALAQYVMNSQKGGSELKTWGLILGALKAAREEEKVWEEARRLWSPDQTDPGGGSQGVSSDVKQQCRPGGSLSCRNSDEEHSTKIAPSDPNTPGQTTGDKQQDGRIQPSAPLSGEDTLSQGLESPPPYPRQPLYPSLQNFTPPTGAEKGVEEQGGGIPAPSHGAVKGAEEKRGGVFVPTQGVKNRHHTPPEGAGGRRGTDWQGIKDAVEEKGLLTAFPAVLGEEGPEWTPLDPKGVTRLIEAVEKKGLRSPVTINALEALTEPGPMLPYDIENLMRMVLKPVQYTLWKEEWLTELKRVIAAAQDDPGHPVHGTDLMRLMGSAAGMATPRAQLAQLRPGELIATTDAAIGAFRKFARRVEPSTPWSEIAQGPTESFQEFTDRIIKAVEGSDLPRAVHGPVIVDCLKQRSLEDIKTLLRAAPRKIATPEEIIRYVLDKQKTTPLTNEGLAAAITNIMAVTLRPLRAAESYRGPCFQCGQFGHNKAQCTTPMDDEKGGLCFRCGQFGHIKVQCRAMRHGERGRVICQLCGKAGHSARQCRSVRVQQQGNEWGRVPQAQGPSQSSQDGPSMTPTWSLPVRPAPNLKFLTRPPWH", "length": 645, "header": "tr|A0A8V1AK09-1|A0A8V1AK09_CHICK Isoform 1 of Gag polyprotein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AK09-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AK09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK09/entry#A0A8V1AK09-1", "sequence": { "sequence": 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"id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK09" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "viral process", "id": "GO:0016032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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{ "id": "A0A8V1AK42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AK42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14504", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14504", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ 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"categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESPLVLHLGIPPLDPSMESPLFPISGVPHCAPPWRSPCPPPWGTPVCPPLRSPPCPHPWGPPLCSSMGSPLVPHFGVPPCPQPLRPPLSPSVGLGRGQSKDRGGAPVSWYLHGVQPRAPIPPAGWDTEGGGWEGVRPGAASQPLGLRLPVPALRSIPPFPAAPLRPPAAFPGTEGREGPGRGRRGGQAGPGPRFEAMVEPPNFSWVAEGRLAGLGMPREPGHYRFLLGRGVKHLVSLSERPPPHHGCCPAVQLHRFRVPDFTPPTARQIQSFLQLVEEANGRGEAVAVHCMLGHGRTGTMLACYLVKTQKMSGSDAIREIRRLRPGSIETREQEQAVMEFHRRFSAGEDSREA", "length": 354, "header": "tr|A0A8V1AK42-1|A0A8V1AK42_CHICK Isoform 1 of Dual specificity protein phosphatase 23 OS=Gallus gallus OX=9031 GN=DUSP23 PE=3 SV=1 CANONICAL=A0A8V1AK42-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42/entry#A0A8V1AK42-1", "sequence": { "sequence": "MESPLVLHLGIPPLDPSMESPLFPISGVPHCAPPWRSPCPPPWGTPVCPPLRSPPCPHPWGPPLCSSMGSPLVPHFGVPPCPQPLRPPLSPSVGLGRGQSKDRGGAPVSWYLHGVQPRAPIPPAGWDTEGGGWEGVRPGAASQPLGLRLPVPALRSIPPFPAAPLRPPAAFPGTEGREGPGRGRRGGQAGPGPRFEAMVEPPNFSWVAEGRLAGLGMPREPGHYRFLLGRGVKHLVSLSERPPPHHGCCPAVQLHRFRVPDFTPPTARQIQSFLQLVEEANGRGEAVAVHCMLGHGRTGTMLACYLVKTQKMSGSDAIREIRRLRPGSIETREQEQAVMEFHRRFSAGEDSREA", "length": 354, "header": "tr|A0A8V1AK42-1|A0A8V1AK42_CHICK Isoform 1 of Dual specificity protein phosphatase 23 OS=Gallus gallus OX=9031 GN=DUSP23 PE=3 SV=1 CANONICAL=A0A8V1AK42-1" }, "locus": { "chromosome": "25", "start_pos": 2433294, "end_pos": 2431163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069841.1", "url": "https://www.ensembl.org/id/ENSGALT00010069841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042967.1", "url": "https://www.ensembl.org/id/ENSGALP00010042967.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A6D3", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1AK42", "gene_name": "DUSP23", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK42" } ] } ] }, { "uniprot_ac": "A0A8V1AKZ7", "gene_name": "PPM1E", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] } ] }, { "uniprot_ac": "E1BVM8", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] } ] }, { "uniprot_ac": "E1BYA9", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { 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"https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFU3", "url": "https://www.orthodb.org/?gene=A0A8V1AFU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK45", "url": "https://www.orthodb.org/?gene=A0A8V1AK45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRTPSVPPNALYSHLTPPLSHPMPFIPTLLPLCPTLCPLFPPHAPSVPPYALYSHPDPPLSHPMPFFPPRPPSVPPYALYSHPKPPPPPTPELHLPSAPAPPSLSSPPHHWPPASFRYHGDDQSEAPHRRGGVANPSPSHRRCFGGGRPVVAAERCGRFGSGPGDEEPAAAPGAGPRGARRNPAELRRWHPVTGASCGTGTCAMRWWLRAAFLSLLAGTDGSGQSGAVVGRVGDSAVLGCDLLGAQPGRPPLYVIEWVRVGFVLPIFIKFGLYSPRVDPEYSGRVRIEEGASLRIDLLRAEDQGWYECRVLFLDRPSADADFQNGTWIHLTVNAPPTFLVTPPAFVEVRDRDALSLTCTAVGNPQPIISWKRSDLALQSGDTLQVRNGTLSIAAVERASAGTYTCHASSKEGTITHTTRVLVQGPPVIVVPPQNVTVNVSQDAFLACQAEAYPGNLTYTWFQGSSNVFHLSHLQARVRILVDGSLLLQRATPDDAGKYTCIASNGLWKPPSASAFITVLYPAQVTTMLPETHLPKGMRGIIRCPTRANPPLLSVSWTRDGRPLELGKFPGWSTRSDGSIVIATGNDDALGVYTCTPYNSYGTAGASRPTRVLLKDPPTFTVRPKEEYFQEVGRELVIPCTAHGDPPPTITWGKVGSAGQIGAQVDGNSSLIFHPLIKEQHGVWECTATNAVASVSTATTVHVLGTSPHAVTNVSVLPLLLAANISWEPGFDGGYFQRFSVWYTPLVKHPPRAHHDWVSLAVPPGAQHLLVENLQPDTSYQFSVLAQNKLGSGPFSQIVTSVPRGFPVTTVPPEPPAVTVHILLSPPQALSANETARGVLLRWQPPAQLSVPLSGYALELRQDRGGWEVLERSIPSTESQVLVPGLIKDAFYEFRLVAFAGSYISDPSNTVNVSTAGMEVYPSRTQLPELLPQPVLAGVIGGICFLSVAIIFSTTAACIMNRRRAARIQKRRQDPPLVFSPSKKLPAAHPSHAADSPPSTAKLKLQPSPCPSLRRALLWGEKAGTSLGLSIAGGSAAGYALYESHVGEHVPLERIRRGPDGRFVVESTETTPQQRDPPPARRQETEPIWHKEVALRPRPPGNPPAPSGRRRGRYFGYGSSSPVDEGTALCIVDVSPVASAATLPYSPDPPSARWDSLPPRGTPPDSNTPQRTASPPPQSGILQYLSLPFFKEMCVDGDWPPPEEAPQPPTPPQQQPGGGQDCADPCAKLPPAPTLLQPPKVPLGPLKASLPGPPVWPTPPEPTRRGPPIDKTENREVPPPEKLPRGSLTSQSSGRGSASFLRPPSLAPSLGGPGPGTPPADGGSWKVGTEPIHVVGGKRRDTSVDESYEWDAEVTLATDLLAALQLYRTAEPPRPLSTIALRDLERQKPGGGGSTPVTSVSAEALVAAGGPPPHGRHREGAQQRRRQRPGGGRGGCGERCELATLL", "length": 1447, "header": "tr|A0A8V1AK45-1|A0A8V1AK45_CHICK Isoform 1 of Immunoglobulin superfamily member 9 OS=Gallus gallus OX=9031 GN=IGSF9 PE=1 SV=1 CANONICAL=A0A8V1AK45-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45/entry#A0A8V1AFU3-1", "sequence": { "sequence": "MAVARGCRGEDGGVLLSVGEEEELRPALGGIRGVPCALIRAKGTFVWSLLFPAPSWRLWGCSVRPCGAMPSFPSLPRPPSAPGKRKLGRGCRESRAARGRVRIEEGASLRIDLLRAEDQGWYECRVLFLDRPSADADFQNGTWIHLTVNAPPTFLVTPPAFVEVRDRDALSLTCTAVGNPQPIISWKRSDLALQSGDTLQVRNGTLSIAAVERASAGTYTCHASSKEGTITHTTRVLVQGPPVIVVPPQNVTVNVSQDAFLACQAEAYPGNLTYTWFQGSSNVFHLSHLQARVRILVDGSLLLQRATPDDAGKYTCIASNGLWKPPSASAFITVLYPAQVTTMLPETHLPKGMRGIIRCPTRANPPLLSVSWTRDGRPLELGKFPGWSTRSDGSIVIATGNDDALGVYTCTPYNSYGTAGASRPTRVLLKDPPTFTVRPKEEYFQEVGRELVIPCTAHGDPPPTITWGKVGSAGQIGAQVDGNSSLIFHPLIKEQHGVWECTATNAVASVSTATTVHVLGTSPHAVTNVSVLPLLLAANISWEPGFDGGYFQRFSVWYTPLVKHPPRAHHDWVSLAVPPGAQHLLVENLQPDTSYQFSVLAQNKLGSGPFSQIVTSVPRGFPVTTVPPEPPAVTVHILLSPPQALSANETARGVLLRWQPPAQLSVPLSGYALELRQDRGGWEVLERSIPSTESQVLVPGLIKDAFYEFRLVAFAGSYISDPSNTVNVSTAGMEVYPSRTQLPELLPQPVLAGVIGGICFLSVAIIFSTTAACIMNRRRAARIQKRRQDPPLVFSPSKKLPAAHPSHAADSPPSTAKLKLQPSPCPSLRRALLWGEKAGTSLGLSIAGGSAAGYALYESHVGEHVPLERIRRGPDGRFVVESTETTPQQRDPPPARRQETEPIWHKEVALRPRPPGNPPAPSGRRRGRYFGYGSSSPVDEGTALCIVDVSPVASAATLPYSPDPPSARWDSLPPRGTPPDSNTPQRTASPPPQSGILQYLSLPFFKEMCVDGDWPPPEEAPQPPTPPQQQPGGGQDCADPCAKLPPAPTLLQPPKVPLGPLKASLPGPPVWPTPPEPTRRGPPIDKTENREVPPPEKLPRGSLTSQSSGRGSASFLRPPSLAPSLGGPGPGTPPADGGSWKVGTEPIHVVGGKRRDTSVDESYEWDAEVTLATDLLAALQLYRTAEPPRPLSTIALRDLERQKPGGGGSTPVTSVSAEALVAAGGPPPHGRHREGAQQRRRQRPGGGRGGCGERCELATLL", "length": 1261, "header": "tr|A0A8V1AFU3-1|A0A8V1AFU3_CHICK Computationally mapped isoform of Immunoglobulin superfamily member 9 OS=Gallus gallus OX=9031 GN=IGSF9 PE=4 SV=1 CANONICAL=A0A8V1AK45-1" }, "locus": { "chromosome": "25", "start_pos": 2446255, "end_pos": 2437955, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069845.1", "url": "https://www.ensembl.org/id/ENSGALT00010069845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042971.1", "url": "https://www.ensembl.org/id/ENSGALP00010042971.1" } ] } }, { "isoform_ac": "A0A8V1AK45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45/entry#A0A8V1AK45-1", "sequence": { "sequence": "MAPRTPSVPPNALYSHLTPPLSHPMPFIPTLLPLCPTLCPLFPPHAPSVPPYALYSHPDPPLSHPMPFFPPRPPSVPPYALYSHPKPPPPPTPELHLPSAPAPPSLSSPPHHWPPASFRYHGDDQSEAPHRRGGVANPSPSHRRCFGGGRPVVAAERCGRFGSGPGDEEPAAAPGAGPRGARRNPAELRRWHPVTGASCGTGTCAMRWWLRAAFLSLLAGTDGSGQSGAVVGRVGDSAVLGCDLLGAQPGRPPLYVIEWVRVGFVLPIFIKFGLYSPRVDPEYSGRVRIEEGASLRIDLLRAEDQGWYECRVLFLDRPSADADFQNGTWIHLTVNAPPTFLVTPPAFVEVRDRDALSLTCTAVGNPQPIISWKRSDLALQSGDTLQVRNGTLSIAAVERASAGTYTCHASSKEGTITHTTRVLVQGPPVIVVPPQNVTVNVSQDAFLACQAEAYPGNLTYTWFQGSSNVFHLSHLQARVRILVDGSLLLQRATPDDAGKYTCIASNGLWKPPSASAFITVLYPAQVTTMLPETHLPKGMRGIIRCPTRANPPLLSVSWTRDGRPLELGKFPGWSTRSDGSIVIATGNDDALGVYTCTPYNSYGTAGASRPTRVLLKDPPTFTVRPKEEYFQEVGRELVIPCTAHGDPPPTITWGKVGSAGQIGAQVDGNSSLIFHPLIKEQHGVWECTATNAVASVSTATTVHVLGTSPHAVTNVSVLPLLLAANISWEPGFDGGYFQRFSVWYTPLVKHPPRAHHDWVSLAVPPGAQHLLVENLQPDTSYQFSVLAQNKLGSGPFSQIVTSVPRGFPVTTVPPEPPAVTVHILLSPPQALSANETARGVLLRWQPPAQLSVPLSGYALELRQDRGGWEVLERSIPSTESQVLVPGLIKDAFYEFRLVAFAGSYISDPSNTVNVSTAGMEVYPSRTQLPELLPQPVLAGVIGGICFLSVAIIFSTTAACIMNRRRAARIQKRRQDPPLVFSPSKKLPAAHPSHAADSPPSTAKLKLQPSPCPSLRRALLWGEKAGTSLGLSIAGGSAAGYALYESHVGEHVPLERIRRGPDGRFVVESTETTPQQRDPPPARRQETEPIWHKEVALRPRPPGNPPAPSGRRRGRYFGYGSSSPVDEGTALCIVDVSPVASAATLPYSPDPPSARWDSLPPRGTPPDSNTPQRTASPPPQSGILQYLSLPFFKEMCVDGDWPPPEEAPQPPTPPQQQPGGGQDCADPCAKLPPAPTLLQPPKVPLGPLKASLPGPPVWPTPPEPTRRGPPIDKTENREVPPPEKLPRGSLTSQSSGRGSASFLRPPSLAPSLGGPGPGTPPADGGSWKVGTEPIHVVGGKRRDTSVDESYEWDAEVTLATDLLAALQLYRTAEPPRPLSTIALRDLERQKPGGGGSTPVTSVSAEALVAAGGPPPHGRHREGAQQRRRQRPGGGRGGCGERCELATLL", "length": 1447, "header": "tr|A0A8V1AK45-1|A0A8V1AK45_CHICK Isoform 1 of Immunoglobulin superfamily member 9 OS=Gallus gallus OX=9031 GN=IGSF9 PE=1 SV=1 CANONICAL=A0A8V1AK45-1" }, "locus": { "chromosome": "25", "start_pos": 2446255, "end_pos": 2435106, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069846.1", "url": "https://www.ensembl.org/id/ENSGALT00010069846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042972.1", "url": "https://www.ensembl.org/id/ENSGALP00010042972.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1211, "start_aa": "Thr", "end_pos": 1211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1211", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1259, "start_aa": "Thr", "end_pos": 1259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1259", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45" } ], "pmid": "" }, { "name": "inhibitory synapse", "id": "GO:0060077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 834, "end_pos": 836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 913, "end_pos": 915, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 708, "end_pos": 814, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK45" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 312, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 92, 1211, 1259 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 326, "end_pos": 328 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 440, "end_pos": 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"ac": "XP_015151140", "name": "transmembrane and immunoglobulin domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151140" }, "gene_names": [ { "name": "TMIGD1", "type": "recommended", "evidence": [ { "id": "A0A8V1AK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK72" } ] }, { "name": "TMIGD1", "type": "synonym", "evidence": [ { "id": "XP_015151140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151140" } ] } ], "protein_names": [ { "name": "Transmembrane and immunoglobulin domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK72/entry#names_and_taxonomy" } ] }, { "name": "transmembrane and immunoglobulin domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151140", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151140.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151140" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK72", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK72" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMIGD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK72", "locus": { "chromosome": "19", "start_pos": 6724917, "end_pos": 6729360, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029712", "url": "https://www.ensembl.org/id/ENSGALG00010029712" } ] } } ], "crossref": [ { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101751326", "url": "https://www.ncbi.nlm.nih.gov/gene/101751326", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TCQLARN", "url": "https://omabrowser.org/oma/group/TCQLARN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK72", "url": "https://www.orthodb.org/?gene=A0A8V1AK72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45889", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45889", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45889:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45889:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": 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CANONICAL=A0A8V1AK72-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AK72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK72/entry#A0A8V1AK72-1", "sequence": { "sequence": "MAQRSRLTASCRAHVLVLCFLAHVATGVELSVNNHNDDFTLTISSGSLASLSCLAQNSSQAEELLWYRGDGRVDLKDENKVNISNICISPVSESDNGVAFTCRLLRDQSVQVSVVLDVRFPPSAGEDESIYIEEGKDVTLTCNAKSNPQGQTTWYKNNTILTLHDHYQVYQNSETFQLSIRKVQKSDNGTYTCEVKSSCGDSSKDFHLIVEDKKPVFPTEAVIAAVVVVVLTGLFGIVAQKEKIFKCFKKPSQTAL", "length": 256, "header": "tr|A0A8V1AK72-1|A0A8V1AK72_CHICK Isoform 1 of Transmembrane and immunoglobulin domain containing 1 OS=Gallus gallus OX=9031 GN=TMIGD1 PE=4 SV=1 CANONICAL=A0A8V1AK72-1" }, "locus": { "chromosome": "19", "start_pos": 6728948, "end_pos": 6725319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071865.1", "url": "https://www.ensembl.org/id/ENSGALT00010071865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044555.1", "url": "https://www.ensembl.org/id/ENSGALP00010044555.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 219, "start_aa": "Thr", "end_pos": 219, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr219", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RMH4-1", "protein_name": "Transmembrane and immunoglobulin domain-containing protein 1", "gene_name": "TMIGD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AK80-1", "uniprot_ac": "A0A8V1AK80", "uniprot_id": "A0A8V1AK80_CHICK", "mass": { "chemical_mass": 54769.0, "monoisotopic_mass": 54769.0 }, "refseq": { "ac": "XP_040506519", "name": "protein spinster homolog 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506519" }, "gene_names": [ { "name": "SPNS3", "type": "recommended", "evidence": [ { "id": "A0A8V1AK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80" } ] }, { "name": "SPNS3", "type": "synonym", "evidence": [ { "id": "XP_040506519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506519" } ] } ], "protein_names": [ { "name": "SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)", "type": "synonym", "evidence": [ { "id": "A0A8V1AK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80/entry#names_and_taxonomy" } ] }, { "name": "protein spinster homolog 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040506519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506519" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506519" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPNS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80", "locus": { "chromosome": "19", "start_pos": 3593595, "end_pos": 3624968, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029427", "url": "https://www.ensembl.org/id/ENSGALG00010029427" } ] } } ], "crossref": [ { "id": "A0A8V1AK80", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AK80", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417493", "url": "https://www.ncbi.nlm.nih.gov/gene/417493", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YTCVYTA", "url": "https://omabrowser.org/oma/group/YTCVYTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACZ2", "url": "https://www.orthodb.org/?gene=A0A8V1ACZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK80", "url": "https://www.orthodb.org/?gene=A0A8V1AK80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANQ9", "url": "https://www.orthodb.org/?gene=A0A8V1ANQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23505:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23505:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506519", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNPSADENTDLQPRVPSEEQNYGATAARVRRGPHVRVSRNSPAKRDYLIVGVLCYANLINFMDWFIVPGILLDIQKYFDLSDGAAGLLQTVFILCYMLAAPFFGYLGDRYNRKAIIGAGIFFWSAVTLGTSFISESYYWIFFLSRGLVGIGTASYSTVAPTIIADRFDEGKRTTMLSVFYICIPMGSGLGYVLASSMTHVTGDWHWAFRVTPCMGGLALVLLILLVPHRIQRRTEAHRALSIHGSIRVAAEKPGAQGAAKTSWCQDVISLGKNWSFVWSSLGLTAMAFVTGALGLWVPMFLYRAQVALGTVQQCLEKSCNSSNSLIFGGITIGTGILGVIAGAEAARRLRKTNNRADPLICATSMFASSLCLYIAIMVAQKNILSTFIFIAFGELFLSVNWAVVTDILLYVVTPRRQSTAIALQILVSHLLGDAGSPYLVGMISNAIQAKKDQSFHWSFCSLQYSFIICVFVGVFGGVFFLLTSFYIEEDRKEAEQF", "length": 498, "header": "tr|A0A8V1AK80-1|A0A8V1AK80_CHICK Isoform 1 of SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative) OS=Gallus gallus OX=9031 GN=SPNS3 PE=3 SV=1 CANONICAL=A0A8V1AK80-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80/entry#A0A8V1ACZ2-1", "sequence": { "sequence": "MTYSYSCSLFLNFKSAGEAEPASFPRQKHDLHAWKMKTICGLYLFHSCHHCLCISLEWNISGILLDIQKYFDLSDGAAGLLQTVFILCYMLAAPFFGYLGDRYNRKAIIGAGIFFWSAVTLGTSFISESYYWIFFLSRGLVGIGTASYSTVAPTIIADRFDEGKRTTMLSVFYICIPMGSGLGYVLASSMTHVTGDWHWAFRVTPCMGGLALVLLILLVPHRIQRRTEAHRALSIHGSIRVAAEKPGAQGAAKTSWCQDVISLGKNWSFVWSSLGLTAMAFVTGALGLWVPMFLYRAQVALGTVQQCLEKSCNSSNSLIFGGITIGTGILGVIAGAEAARRLRKTNNRADPLICATSMFASSLCLYIAIMVAQKNILSTFIFIAFGELFLSVNWAVVTDILLYVVTPRRQSTAIALQILVSHLLGDAGSPYLVGMISNAIQAKKDQSFHWSFCSLQYSFIICVFVGVFGGVFFLLTSFYIEEDRKEAEQF", "length": 490, "header": "tr|A0A8V1ACZ2-1|A0A8V1ACZ2_CHICK Computationally mapped isoform of SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative) OS=Gallus gallus OX=9031 GN=SPNS3 PE=3 SV=1 CANONICAL=A0A8V1AK80-1" }, "locus": { "chromosome": "19", "start_pos": 3621548, "end_pos": 3593742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071193.1", "url": "https://www.ensembl.org/id/ENSGALT00010071193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043884.1", "url": "https://www.ensembl.org/id/ENSGALP00010043884.1" } ] } }, { "isoform_ac": "A0A8V1AK80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80/entry#A0A8V1AK80-1", "sequence": { "sequence": "MQNPSADENTDLQPRVPSEEQNYGATAARVRRGPHVRVSRNSPAKRDYLIVGVLCYANLINFMDWFIVPGILLDIQKYFDLSDGAAGLLQTVFILCYMLAAPFFGYLGDRYNRKAIIGAGIFFWSAVTLGTSFISESYYWIFFLSRGLVGIGTASYSTVAPTIIADRFDEGKRTTMLSVFYICIPMGSGLGYVLASSMTHVTGDWHWAFRVTPCMGGLALVLLILLVPHRIQRRTEAHRALSIHGSIRVAAEKPGAQGAAKTSWCQDVISLGKNWSFVWSSLGLTAMAFVTGALGLWVPMFLYRAQVALGTVQQCLEKSCNSSNSLIFGGITIGTGILGVIAGAEAARRLRKTNNRADPLICATSMFASSLCLYIAIMVAQKNILSTFIFIAFGELFLSVNWAVVTDILLYVVTPRRQSTAIALQILVSHLLGDAGSPYLVGMISNAIQAKKDQSFHWSFCSLQYSFIICVFVGVFGGVFFLLTSFYIEEDRKEAEQF", "length": 498, "header": "tr|A0A8V1AK80-1|A0A8V1AK80_CHICK Isoform 1 of SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative) OS=Gallus gallus OX=9031 GN=SPNS3 PE=3 SV=1 CANONICAL=A0A8V1AK80-1" }, "locus": { "chromosome": "19", "start_pos": 3616200, "end_pos": 3593742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071192.1", "url": "https://www.ensembl.org/id/ENSGALT00010071192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043883.1", "url": "https://www.ensembl.org/id/ENSGALP00010043883.1" } ] } }, { "isoform_ac": "A0A8V1ANQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80/entry#A0A8V1ANQ9-1", "sequence": { "sequence": "MWIIRILLDIQKYFDLSDGAAGLLQTVFILCYMLAAPFFGYLGDRYNRKAIIGAGIFFWSAVTLGTSFISESYYWIFFLSRGLVGIGTASYSTVAPTIIADRFDEGKRTTMLSVFYICIPMGSGLGYVLASSMTHVTGDWHWAFRVTPCMGGLALVLLILLVPHRIQRRTEAHRALSIHGSIRVAAEKPGAQGAAKTSWCQDVISLGKNWSFVWSSLGLTAMAFVTGALGLWVPMFLYRAQVALGTVQQCLEKSCNSSNSLIFGGITIGTGILGVIAGAEAARRLRKTNNRADPLICATSMFASSLCLYIAIMVAQKNILSTFIFIAFGELFLSVNWAVVTDILLYVVTPRRQSTAIALQILVSHLLGDAGSPYLVGMISNAIQAKKDQSFHWSFCSLQYSFIICVFVGVFGGVFFLLTSFYIEEDRKEAEQF", "length": 433, "header": "tr|A0A8V1ANQ9-1|A0A8V1ANQ9_CHICK Computationally mapped isoform of SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative) OS=Gallus gallus OX=9031 GN=SPNS3 PE=3 SV=1 CANONICAL=A0A8V1AK80-1" }, "locus": { "chromosome": "19", "start_pos": 3621432, "end_pos": 3593742, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071194.1", "url": "https://www.ensembl.org/id/ENSGALT00010071194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043885.1", "url": "https://www.ensembl.org/id/ENSGALP00010043885.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZPL7-1", "protein_name": "Sphingolipid transporter 3", "gene_name": "Spns3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRECIKPQTGGPQSQSLSPGGQYGALASGNCLPPSTSASWSLPRWRAYLAAAVLCYVNLLNYMNWFIIPGVLLDVQKYFHISDSHAGLLQTVFIGCLLVSAPVFGYLGDRYSRKAILSFGVLLWSGAGLSSSFISYQYSWLFFLSRGIVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRIMPCLDAVALALLILLVPDLPRGAAEKQGEVPVRAPRSSWYEDVRYLGRNWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGIIGVMLGAEASRKYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPNSYLQHFLSLQHSFLCCAFAIVLGGGCFLLTALHLERDQARARQPGEETLDSKDIARRDTERQGLLSGTSTPTE", "length": 514 }, "evidence": [ { "id": "A0A8V1AK80", "url": "https://omabrowser.org/oma/group/A0A8V1AK80/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2CER7-1", "protein_name": "Protein spinster homolog 3", "gene_name": "spns3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASDQHRPKPRLSLRSSTTIRYGSMSSEHPDGDPSTPQTTSISQRRSYIAVAVLCYINLLNYMDRYTIAGVLLRIQKFFFISDSTSGLLQTVFICSFMFLAPVFGYLGDRYDRKLIMIVGLVMWIVTTLGSSFVRKSHFWVLVATRALVGTGEASYSTIAPTIIGDLFAGSKRTLMISFFYIFIPVGSGLGYIIGATVADATGDWRWALRVSPALGGLGLLLLVFLIPNPPRGASDNGGANMETTSYTEDIKYLLKNRSFVWSSLGVTAMAFVTGALAFWTPTFLSRAQVTQGLKQPCKEEPCDSVDSYIFGAITVVTGVVGVFLGTCISKKLRDRVPNADPLICAVGMLSSSPCFFIAIVLASTSIPATYTFIAIGETLLSLNWAILADILLYVVVPNRRATAEALQIMVCHLLGDAGSPYLIGAISDSLSKYNTTDPSWDFRRLEYSVLLCPFIGVLGGLFFLMTSLYIKEDRKAAELLTSGQTPQPEITTVSESV", "length": 498 }, "evidence": [ { "id": "A0A8V1AK80", "url": "https://omabrowser.org/oma/group/A0A8V1AK80/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1ME77-1", "protein_name": "SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)", "gene_name": "SPNS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVEFRQPEGLHGQSPGPGGPSRATDTDPPSLPAPWSLPRWRAYVAAAVLCYINLLNYMNWFIIAGVLLDVQKFFHISDSNAGLLQTVFISFLLLSAPVFGYLGDRHSRKATLSFGILLWSGAGLSSSFISPRYSWLFFLSRGLVGTGTASYSTIAPTVLGDLFVRDQRTRVLAIFYIFIPVGSGLGYVLGSAVAELTGNWRWALRIMPCLEAVALILLIMLVPDPPRGAAEKQGVATTGDPRSSWCEDVRYLWRNWSFVWSTLGVTAMAFVTGALGFWAPKFLFEARVVHGLLLPCFREPCNSQDSLIFGALTVVTGIIGVILGAETSRRYKKVNPQAEPLICAASLLAAAPCLYLALILAPTTLLASYVFLALGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVGHILGDAGSPYLMGLVSALQAGRPDTYLQRFLSLQQSFLCCAFVIALGGGCFLLTALYLERDQAQAQKSGTGTLLLCTHAGLRADPIETKSTGHPLNLLIYPFIHLLIHAHVIIMPLLCARQDCRSWGVNIKSKPT", "length": 546 }, "evidence": [ { "id": "A0A8V1AK80", "url": "https://omabrowser.org/oma/group/A0A8V1AK80/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4IKF6-1", "protein_name": "Probable sphingolipid transporter spinster homolog 3", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVTKEEDCLPPVTETTSRCYSTSSSTPLAELETVRSLEIVESSSSLSPVWLLVIFCIINLLNYMDRGAIASNGVNGSTRSCNDKGKCTLATGIQGHFNLSNFEDGVLSSSFMVGLLIASPIFASLAKRLIGVGLTVWTIAVLGCGSSFAFWFIVLCRMFVGVGEASFISLAAPFIDDNAPQEQKAAWLGLFYMCIPSGVALGYVYGGYVGKHFSWRYAFWGEAVLMAPFAVLGFLMKPLQLKGSETLKNNNRLQVDNEIEHDQFEVSIETSKSSYANAVFKSFTGFAKDMKVLYKEKVFVVNVLGYVSYNFVIGAYSYWGPKAGYNIYKMKNADMIFGAVTIICGIVGTLSGGFILDRVTATIPNAFKLLSGATFLGAVFCFTAFTLKSLYGFIALFALGELLVFATQAPVNYVCLHCVKPSLRPLSMAISTVAIHIFGDVPSSPLVGIVQDHINSWRKTTLILTSILFLAAAIWFIGKINLNSFYSNDESFLVQIKLFVANLCFCKGYS", "length": 510 }, "evidence": [ { "id": "A0A8V1AK80", "url": "https://omabrowser.org/oma/group/A0A8V1AK80/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6ZMD2-1", "protein_name": "Protein spinster homolog 3", "gene_name": "SPNS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGMSAECPEPGPGGLQGQSPGPGRQCPPPITPTSWSLPPWRAYVAAAVLCYINLLNYMNWFIIAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFGILLWSGAGLSSSFISPRYSWLFFLSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLGSAVTMLTGNWRWALRVMPCLEAVALILLILLVPDPPRGAAETQGEGAVGGFRSSWCEDVRYLGKNWSFVWSTLGVTAMAFVTGALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVIGVILGAEAARRYKKVIPGAEPLICASSLLATAPCLYLALVLAPTTLLASYVFLGLGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVGHILGDAGSPYLTGLISSVLRARRPDSYLQRFRSLQQSFLCCAFVIALGGGCFLLTALYLERDETRAWQPVTGTPDSNDVDSNDLERQGLLSGAGASTEEP", "length": 512 }, "evidence": [ { "id": "A0A8V1AK80", "url": "https://omabrowser.org/oma/group/A0A8V1AK80/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D232-1", "protein_name": "Protein spinster homolog 3", "gene_name": "Spns3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTECLKPQTGGPQSQSLSQGGQYGALASGTCLPPSTPVPWSLPRWRAYLAAAVLCYINLLNYMNWFIIPGVLLDVQKYFHISDSHAGLLQTVFISCLLVSAPVFGYLGDRYNRKAILSFGILLWSGAGLSSSFISYQYSWLFFLSRGFVGTGAASYSTIAPTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRLMPCLDAMALALLILLVPDVPRGAAEKQGEVAVRAPRSSWCEDVRYLGRNWSFVFSTLGVTAIAFVTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGIIGVMLGAEASRRYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWAVVADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPDSYLQHFLSLQHSFLCCAFAIVLGGGFFLLTALHLEKDQARARQPGKGTLDSKDIASRNTESQGLLSGTSTPTE", "length": 514 }, "evidence": [ { "id": "A0A8V1AK80", "url": "https://omabrowser.org/oma/group/A0A8V1AK80/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AK80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK80" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 492, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 212 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AK82-1", "uniprot_ac": "A0A8V1AK82", "uniprot_id": "A0A8V1AK82_CHICK", "mass": { "chemical_mass": 28937.0, "monoisotopic_mass": 28937.0 }, "refseq": {}, "gene_names": [ { "name": "TUSC5", "type": "recommended", "evidence": [ { "id": "A0A8V1AK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82" } ] } ], "protein_names": [ { "name": "Trafficking regulator of GLUT4 (SLC2A4) 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TUSC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82", "locus": {} } ], "crossref": [ { "id": "A0A8V1AK82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AK82", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK82", "url": "https://www.orthodb.org/?gene=A0A8V1AK82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14948:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14948:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AK82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGDVAPAGSGSGSGSGTVLPSRLQETEKLLAATEGREGLRGSKSFTAALAGEAERNGHGLSYKSVSVGHLEAAPLSPSRLSLGRASSTATSTAAPDQGRPRDYLVLAIFSCFCPVWPINVVALVFSIMSRNSGQQGDMDGARRLGRMARLLSIVSIVLGTIIIVLYVSLSVRALQQKLVTAEPVWRNVRGCSTAFWGRAGMGTRRGDEGQELDMSREEKGKSTTSFPSNGAGRPRWGMDRRRRRREIPDRSSFEGKPKDGPRHFEESS", "length": 270, "header": "tr|A0A8V1AK82-1|A0A8V1AK82_CHICK Isoform 1 of Trafficking regulator of GLUT4 (SLC2A4) 1 OS=Gallus gallus OX=9031 GN=TUSC5 PE=3 SV=1 CANONICAL=A0A8V1AK82-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AK82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82/entry#A0A8V1AK82-1", "sequence": { "sequence": "MASGDVAPAGSGSGSGSGTVLPSRLQETEKLLAATEGREGLRGSKSFTAALAGEAERNGHGLSYKSVSVGHLEAAPLSPSRLSLGRASSTATSTAAPDQGRPRDYLVLAIFSCFCPVWPINVVALVFSIMSRNSGQQGDMDGARRLGRMARLLSIVSIVLGTIIIVLYVSLSVRALQQKLVTAEPVWRNVRGCSTAFWGRAGMGTRRGDEGQELDMSREEKGKSTTSFPSNGAGRPRWGMDRRRRRREIPDRSSFEGKPKDGPRHFEESS", "length": 270, "header": "tr|A0A8V1AK82-1|A0A8V1AK82_CHICK Isoform 1 of Trafficking regulator of GLUT4 (SLC2A4) 1 OS=Gallus gallus OX=9031 GN=TUSC5 PE=3 SV=1 CANONICAL=A0A8V1AK82-1" }, "locus": { "chromosome": "19", "start_pos": 6791193, "end_pos": 6786611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071875.1", "url": "https://www.ensembl.org/id/ENSGALT00010071875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044565.1", "url": "https://www.ensembl.org/id/ENSGALP00010044565.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cellular response to insulin stimulus", "id": "GO:0032869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82" } ], "pmid": "" }, { "name": "endosome to plasma membrane protein transport", "id": "GO:0099638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099638", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKA5-1", "uniprot_ac": "A0A8V1AKA5", "uniprot_id": "A0A8V1AKA5_CHICK", "mass": { "chemical_mass": 39396.0, "monoisotopic_mass": 39396.0 }, "refseq": { "ac": "XP_040505608", "name": "phosphoribosyl pyrophosphate synthase-associated protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505608" }, "gene_names": [ { "name": "PRPSAP1", "type": "recommended", "evidence": [ { "id": "A0A8V1AKA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ] }, { "name": "PRPSAP1", "type": "synonym", "evidence": [ { "id": "XP_040505608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505608" } ] } ], "protein_names": [ { "name": "Phosphoribosyl pyrophosphate synthetase associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AKA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5/entry#names_and_taxonomy" } ] }, { "name": "phosphoribosyl pyrophosphate synthase-associated protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_040505608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505608" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505608" } ] }, { "annotation": "Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5#function" }, { "database": "UniProtKB", "id": "ARBA00037514", "url": "https://www.uniprot.org/uniprotkb/ARBA00037514#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRPSAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5", "locus": { "chromosome": "18", "start_pos": 5087193, "end_pos": 5063429, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029446", "url": "https://www.ensembl.org/id/ENSGALG00010029446" } ] } } ], "crossref": [ { "id": "A0A8V1AKA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "417360", "url": "https://www.ncbi.nlm.nih.gov/gene/417360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GIIACPG", "url": "https://omabrowser.org/oma/group/GIIACPG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKA5", "url": "https://www.orthodb.org/?gene=A0A8V1AKA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10210:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10210:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNAARSGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTSCARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLIQYIQEEIPDYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTEQDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIFVMATHGLLSADAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356, "header": "tr|A0A8V1AKA5-1|A0A8V1AKA5_CHICK Isoform 1 of Phosphoribosyl pyrophosphate synthetase associated protein 1 OS=Gallus gallus OX=9031 GN=PRPSAP1 PE=1 SV=1 CANONICAL=A0A8V1AKA5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5/entry#A0A8V1AKA5-1", "sequence": { "sequence": "MNAARSGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTSCARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLIQYIQEEIPDYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTEQDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIFVMATHGLLSADAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356, "header": "tr|A0A8V1AKA5-1|A0A8V1AKA5_CHICK Isoform 1 of Phosphoribosyl pyrophosphate synthetase associated protein 1 OS=Gallus gallus OX=9031 GN=PRPSAP1 PE=1 SV=1 CANONICAL=A0A8V1AKA5-1" }, "locus": { "chromosome": "18", "start_pos": 5085957, "end_pos": 5064069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071227.1", "url": "https://www.ensembl.org/id/ENSGALT00010071227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043918.1", "url": "https://www.ensembl.org/id/ENSGALP00010043918.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1RWP0-1", "protein_name": "Phosphoribosyl pyrophosphate synthetase associated protein 1", "gene_name": "PRPSAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKKLLLLPPLSVSSAFRAPRACPASRPAMNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCAELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 385 }, "evidence": [ { "id": "A0A8V1AKA5", "url": "https://omabrowser.org/oma/group/A0A8V1AKA5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08DW2-1", "protein_name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "gene_name": "PRPSAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIQESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCAEMDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYRIYVMATHGILSAEAPRLIEESSIDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "A0A8V1AKA5", "url": "https://omabrowser.org/oma/group/A0A8V1AKA5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q14558-1", "protein_name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "gene_name": "PRPSAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "A0A8V1AKA5", "url": "https://omabrowser.org/oma/group/A0A8V1AKA5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54QU9-1", "protein_name": "Ribose-phosphate pyrophosphokinase C", "gene_name": "prsC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKTMESVRLISGSAHPQFAELLSKGMNIELSKCESKHFLNGETSVILGESVRSASVYIIQPTCSPNVNDNIMELLVLVDAVRRASSKHITAVIPFFGYGKQNKKEKSREPITGKLIANLIETSGVDRVISMDLEASQIQGFFNIPVDNLYAEPLIVKYIEKHYKHLGEKVVISPAVDGVKRAKLVSDKLNCDLAILDRQTKGDKEDMILVGDVSGKVAIIIGSIADTCETLALSAKILKSKGATNVFALVSHGELSGNAIETLNNSELEELVITNSIPQTEKSKQCPKLKIINVTPMFCEALKRIIHGESITAASSKFVIL", "length": 321 }, "evidence": [ { "id": "A0A8V1AKA5", "url": "https://omabrowser.org/oma/group/A0A8V1AKA5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q63468-1", "protein_name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "gene_name": "Prpsap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "A0A8V1AKA5", "url": "https://omabrowser.org/oma/group/A0A8V1AKA5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D0M1-1", "protein_name": "Phosphoribosyl pyrophosphate synthase-associated protein 1", "gene_name": "Prpsap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAEILKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD", "length": 356 }, "evidence": [ { "id": "A0A8V1AKA5", "url": "https://omabrowser.org/oma/group/A0A8V1AKA5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "5-phosphoribose 1-diphosphate biosynthetic process", "id": "GO:0006015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ], "pmid": "" }, { "name": "purine nucleotide biosynthetic process", "id": "GO:0006164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006164", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA5" }, { "id": "PF13793", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13793" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribose-phosphate pyrophosphokinase N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 126, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 351, "end_pos": 353 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKD0-1", "uniprot_ac": "A0A8V1AKD0", "uniprot_id": "A0A8V1AKD0_CHICK", "mass": { "chemical_mass": 47297.0, "monoisotopic_mass": 47297.0 }, "refseq": { "ac": "NP_001313421", "name": "La ribonucleoprotein domain family, member 6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313421" }, "gene_names": [ { "name": "LARP6L", "type": "recommended", "evidence": [ { "id": "A0A8V1AKD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" } ] }, { "name": "LARP6L", "type": "synonym", "evidence": [ { "id": "NP_001313421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313421" } ] } ], "protein_names": [ { "name": "La ribonucleoprotein domain family member 6", "type": "synonym", "evidence": [ { "id": "A0A8V1AKD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0/entry#names_and_taxonomy" } ] }, { "name": "La ribonucleoprotein domain family, member 6-like", "type": "synonym", "evidence": [ { "id": "NP_001313421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313421" } ] }, { "name": "la-related protein 6-like", "type": "synonym", "evidence": [ { "id": "NP_001313421", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313421" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BM440675.1, BM440429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140853 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000375.1. On Dec 3, 2021 this sequence version replaced NP_001313421.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313421" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LARP6L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0", "locus": { "chromosome": "28", "start_pos": 1999357, "end_pos": 2002299, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028423", "url": "https://www.ensembl.org/id/ENSGALG00010028423" } ] } } ], "crossref": [ { "id": "A0A8V1AKD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420093", "url": "https://www.ncbi.nlm.nih.gov/gene/420093", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420093", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420093", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TRDWRVT", "url": "https://omabrowser.org/oma/group/TRDWRVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKD0", "url": "https://www.orthodb.org/?gene=A0A8V1AKD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22792", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22792", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22792:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22792:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313421", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313421", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRSSVVALGLSSQPSCSTPLSAQRNSFPGLHLPSQSLLLGQDSFFKSSHGSFCDTSDAVGSELFDCSYSIPDPQLIRRIVSQVEFYLSDENLAKDAFLLKHVQKNKLGFVSIKLLTSFKKVKYLTRDWRLTLYALRFSKLLEVNQEGTKVRRRVPIPDSILNIPPTKLLLAWDPLPLEPGTPLPLQKNFIETITQMFSPFGAIASIRILRPGRKLPSDVRKYATRFPELLSHRCALVEYESLESARRACEELGQPCSHSICVVQLSGKGSKRRSGAEGEELVEMLGWKERAEAFHFGVGDSLFCSSPGSDVTSPQLFLAPTWPHGHDFQPGSFSSAFPGSLLSSTAFPPLTAELGFSLGASPKSPDLGWGSTWAPWHSSAPHSPSLDAASPPRTPLAVKPKSCVLRLPHGPDGTRGFYNSIGRGKLVLEH", "length": 432, "header": "tr|A0A8V1AKD0-1|A0A8V1AKD0_CHICK Isoform 1 of La ribonucleoprotein domain family member 6 OS=Gallus gallus OX=9031 GN=LARP6L PE=1 SV=1 CANONICAL=A0A8V1AKD0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0/entry#A0A8V1AKD0-1", "sequence": { "sequence": "MASRSSVVALGLSSQPSCSTPLSAQRNSFPGLHLPSQSLLLGQDSFFKSSHGSFCDTSDAVGSELFDCSYSIPDPQLIRRIVSQVEFYLSDENLAKDAFLLKHVQKNKLGFVSIKLLTSFKKVKYLTRDWRLTLYALRFSKLLEVNQEGTKVRRRVPIPDSILNIPPTKLLLAWDPLPLEPGTPLPLQKNFIETITQMFSPFGAIASIRILRPGRKLPSDVRKYATRFPELLSHRCALVEYESLESARRACEELGQPCSHSICVVQLSGKGSKRRSGAEGEELVEMLGWKERAEAFHFGVGDSLFCSSPGSDVTSPQLFLAPTWPHGHDFQPGSFSSAFPGSLLSSTAFPPLTAELGFSLGASPKSPDLGWGSTWAPWHSSAPHSPSLDAASPPRTPLAVKPKSCVLRLPHGPDGTRGFYNSIGRGKLVLEH", "length": 432, "header": "tr|A0A8V1AKD0-1|A0A8V1AKD0_CHICK Isoform 1 of La ribonucleoprotein domain family member 6 OS=Gallus gallus OX=9031 GN=LARP6L PE=1 SV=1 CANONICAL=A0A8V1AKD0-1" }, "locus": { "chromosome": "28", "start_pos": 2002055, "end_pos": 1999750, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068844.1", "url": "https://www.ensembl.org/id/ENSGALT00010068844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042286.1", "url": "https://www.ensembl.org/id/ENSGALP00010042286.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420093", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420093", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" }, { "id": "PS50961", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50961" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH La-type RNA-binding", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 162, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AKD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD0" }, { "id": "PS51938", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51938" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUZ-C", "eco_id": "ECO_0000259", "start_pos": 379, "end_pos": 423, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKD2-1", "uniprot_ac": "A0A8V1AKD2", "uniprot_id": "A0A8V1AKD2_CHICK", "mass": { "chemical_mass": 283425.0, "monoisotopic_mass": 283425.0 }, "refseq": {}, "gene_names": [ { "name": "NCOR1", "type": "recommended", "evidence": [ { "id": "A0A8V1AKD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ] } ], "protein_names": [ { "name": "Nuclear receptor corepressor 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AKD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation. Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression. The NCOR1-HDAC3 complex regulates the circadian expression of the core clock gene ARTNL/BMAL1 and the genes involved in lipid metabolism in the liver.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2#function" }, { "database": "UniProtKB", "id": "ARBA00054129", "url": "https://www.uniprot.org/uniprotkb/ARBA00054129#function" }, { "database": "UniProtKB", "id": "A0A8V1ANJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANJ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCOR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2", "locus": { "chromosome": "19", "start_pos": 6951037, "end_pos": 7005631, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029731", "url": "https://www.ensembl.org/id/ENSGALG00010029731" } ] } } ], "crossref": [ { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKD2", "url": "https://www.orthodb.org/?gene=A0A8V1AKD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANJ9", "url": "https://www.orthodb.org/?gene=A0A8V1ANJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13992", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13992", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13992:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13992:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27579", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27579", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2173795", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173795", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-350054", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-381340", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381340", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"sequence": { "sequence": "MAVAVALRLSFVKTSSLIMSSSGYPPNQGAFSTEQSRYPTHSVQYTFPSTRHQQEFAVPDYRSSHLEVSQATQLLQQQQQQQQQLRRRPSLLSEFHPGSDRPQERRTGYEQQFHPGPSQTDHDSLESKRPRLEQVSDSHFQRVSAATVLPLVHPLQEGLRSADIKKDPGFGGKHEGPSSPISGQPCGEDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPERPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKEKFVQHPKNFGLIASYLERKNVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKVEEEKAEKADKKDEEKKDEEEKDEKEESKENTKEKDKTEVATEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAQANAAAAAATEEPPPPLPPPPEPSSTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDSLLQQHKQKSSRRPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPTPAETAKPTEETPSESAASKMTTEAAAEQESTVKPAASTSPSLTSQGVSTAESQTSEPQVKEEINTEAEEPMEVDSRSHPVEAKPVLNLPVHTKVEPVETEMRLPENIQVKIESDTKEREMEKPKEKSEPEEMDYSLSQQVNSARQESHSDNDSSATCSADEEVDGEPDRQGIFRESKPSLLNPAGSILVSPTIKQGQMDLQQLHHRAAVIPPMVSCSPCTVPVGTPVSGYALYQRHIKAMHESALLEEQRQRQEQLDMEYRSSVSPCGTSKSPNVEWEGKPVAYMPYAEVKRAIEQEAQVQTTATRSASPYRLSPREVNKASPQPDMNAARYSVPPVLQPAPHQVITNIPEGVRLPTTRPTRPPPPLIPSSKTSVPSEKPSFIMGGSISQGTPGTYLTSHSQASYTQETAKPSVGSISLGLPRQQESAKSASLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTTTIQEGSITRGTPTNKVSVETIPSLRGSITQGTPALSQSGIAADALLKGTITRLATEDSSPEKCREEASAKGHVIYEGKSGHILSYDAIKNVREGTRSPRTAHEISLKRSYDTMEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHAELKERTVLSGSIMQGTPRATSESFEEGLKYPKQIKRESPPIRAFEGAITKGKPYDGVTTIKEMGRSIHEIPRQDLLSQESRKTPEIVQTARPIIEGSISQGTPIKYESNSGQSAIKHNVKSLITGPSKLPRGMPQLEMVPENVKVVERGKYEDVKTGDAVRSRHTSVVSSGPSVLRSTLHETPKSQLSPGIYDDTNARRTPVNYQSPMSRSSPMMNRVSEAGISSGKSANHERKNTLTPTQRESVPAKSPVPGVDPVVAHSPFDPHHRGATPEVYRSHLPPHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVTRGLSPREQTLALPYAGARGIIDLNNMAPTILVPHPGGTSTPPMERITYIPGTQLTFPPRPYNPASLSPGHPTHLAASAAANAEREREREREKERERERERERERERERERERERITSVPAELYLRPGAEQPGRPGSHGYVRSPSPSVRSQENILQQRPSIFQGTNGTSVITPLDPAAQLRIMQLTPGAPSITQGLPASRYNTAADALAALVDAAASAPQMEVAKGKDTKHEGTRIEENVGRRSAVVTEQQQMEQKTLEVEKRAVQCPYTSANFSGGKSQGQSSTVVYSEAGKEKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARDRGSQSSDSSSSLSSHRYEAPGDAIEVISPANSPIPTQEKLQPYQQETPKPSQAESDPNRQYEGPIHRYRAQQEPPPSPQQPPPPSSQAEGMAHVPRTHRLITLADHICQIITQDFARNQAASQASLQPPTTTFQNSTPAPTPVSTRAKTSSRYSPEAQSQPVHHQRPGARVSPENLSDKSRGRPGKSPERSHVSSEPYEPISPPQVPVVHEKQENVLLLSQRAEPTEQRTDSRSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMATAQPGTEIFNLPAVTTSGAVSSRGHSFADPASNLGLEDIIRKALMGNFDDKSEDHGVVMSQSIAVAPGNSSAVVSASNETRREEANPSPNSGGAVSKQKLIGKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPVWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTSIACAPPSMSQATTHQQNRIWEREPAPLLSAQYETLSDSDD", "length": 2553, "header": "tr|A0A8V1AKD2-1|A0A8V1AKD2_CHICK Isoform 1 of Nuclear receptor corepressor 1 OS=Gallus gallus OX=9031 GN=NCOR1 PE=1 SV=1 CANONICAL=A0A8V1AKD2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2/entry#A0A8V1AKD2-1", "sequence": { "sequence": "MAVAVALRLSFVKTSSLIMSSSGYPPNQGAFSTEQSRYPTHSVQYTFPSTRHQQEFAVPDYRSSHLEVSQATQLLQQQQQQQQQLRRRPSLLSEFHPGSDRPQERRTGYEQQFHPGPSQTDHDSLESKRPRLEQVSDSHFQRVSAATVLPLVHPLQEGLRSADIKKDPGFGGKHEGPSSPISGQPCGEDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPERPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKEKFVQHPKNFGLIASYLERKNVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKVEEEKAEKADKKDEEKKDEEEKDEKEESKENTKEKDKTEVATEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAQANAAAAAATEEPPPPLPPPPEPSSTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDSLLQQHKQKSSRRPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPTPAETAKPTEETPSESAASKMTTEAAAEQESTVKPAASTSPSLTSQGVSTAESQTSEPQVKEEINTEAEEPMEVDSRSHPVEAKPVLNLPVHTKVEPVETEMRLPENIQVKIESDTKEREMEKPKEKSEPEEMDYSLSQQVNSARQESHSDNDSSATCSADEEVDGEPDRQGIFRESKPSLLNPAGSILVSPTIKQGQMDLQQLHHRAAVIPPMVSCSPCTVPVGTPVSGYALYQRHIKAMHESALLEEQRQRQEQLDMEYRSSVSPCGTSKSPNVEWEGKPVAYMPYAEVKRAIEQEAQVQTTATRSASPYRLSPREVNKASPQPDMNAARYSVPPVLQPAPHQVITNIPEGVRLPTTRPTRPPPPLIPSSKTSVPSEKPSFIMGGSISQGTPGTYLTSHSQASYTQETAKPSVGSISLGLPRQQESAKSASLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTTTIQEGSITRGTPTNKVSVETIPSLRGSITQGTPALSQSGIAADALLKGTITRLATEDSSPEKCREEASAKGHVIYEGKSGHILSYDAIKNVREGTRSPRTAHEISLKRSYDTMEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHAELKERTVLSGSIMQGTPRATSESFEEGLKYPKQIKRESPPIRAFEGAITKGKPYDGVTTIKEMGRSIHEIPRQDLLSQESRKTPEIVQTARPIIEGSISQGTPIKYESNSGQSAIKHNVKSLITGPSKLPRGMPQLEMVPENVKVVERGKYEDVKTGDAVRSRHTSVVSSGPSVLRSTLHETPKSQLSPGIYDDTNARRTPVNYQSPMSRSSPMMNRVSEAGISSGKSANHERKNTLTPTQRESVPAKSPVPGVDPVVAHSPFDPHHRGATPEVYRSHLPPHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVTRGLSPREQTLALPYAGARGIIDLNNMAPTILVPHPGGTSTPPMERITYIPGTQLTFPPRPYNPASLSPGHPTHLAASAAANAEREREREREKERERERERERERERERERERERITSVPAELYLRPGAEQPGRPGSHGYVRSPSPSVRSQENILQQRPSIFQGTNGTSVITPLDPAAQLRIMQLTPGAPSITQGLPASRYNTAADALAALVDAAASAPQMEVAKGKDTKHEGTRIEENVGRRSAVVTEQQQMEQKTLEVEKRAVQCPYTSANFSGGKSQGQSSTVVYSEAGKEKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARDRGSQSSDSSSSLSSHRYEAPGDAIEVISPANSPIPTQEKLQPYQQETPKPSQAESDPNRQYEGPIHRYRAQQEPPPSPQQPPPPSSQAEGMAHVPRTHRLITLADHICQIITQDFARNQAASQASLQPPTTTFQNSTPAPTPVSTRAKTSSRYSPEAQSQPVHHQRPGARVSPENLSDKSRGRPGKSPERSHVSSEPYEPISPPQVPVVHEKQENVLLLSQRAEPTEQRTDSRSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMATAQPGTEIFNLPAVTTSGAVSSRGHSFADPASNLGLEDIIRKALMGNFDDKSEDHGVVMSQSIAVAPGNSSAVVSASNETRREEANPSPNSGGAVSKQKLIGKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPVWAWEDRPSSTGSTQFPYNPLTMRMLSSTPPTSIACAPPSMSQATTHQQNRIWEREPAPLLSAQYETLSDSDD", "length": 2553, "header": "tr|A0A8V1AKD2-1|A0A8V1AKD2_CHICK Isoform 1 of Nuclear receptor corepressor 1 OS=Gallus gallus OX=9031 GN=NCOR1 PE=1 SV=1 CANONICAL=A0A8V1AKD2-1" }, "locus": { "chromosome": "19", "start_pos": 7005442, "end_pos": 6951662, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071921.1", "url": "https://www.ensembl.org/id/ENSGALT00010071921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044611.1", "url": "https://www.ensembl.org/id/ENSGALP00010044611.1" } ] } }, { "isoform_ac": "A0A8V1ANJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2/entry#A0A8V1ANJ9-1", "sequence": { "sequence": "MSSSGYPPNQGAFSTEQSRYPTHSVQYTFPSTRHQQEFAVPDYRSSHLEVSQATQLLQQQQQQQQQLRRRPSLLSEFHPGSDRPQERRTGYEQQFHPGPSQTDHDSLESKRPRLEQVSDSHFQRVSAATVLPLVHPLQEGLRSADIKKDPGFGGKHEGPSSPISGQPCGEDQNASPSKLSKEELIQSMDRVDREIAKVEQQILKLKKKQQQLEEEAAKPPEPERPVSPPPVEQKHRSIVQIIYDENRKKAEEAHKIFEGLGPKVELPLYNQPSDTKVYHENIKTNQVMRKKLILFFKRRNHARKQREQKICQRYDQLMEAWEKKVDRIENNPRRKAKESKTREYYEKQFPEIRKQREQQERFQRVGQRGAGLSATIARSEHEISEIIDGLSEQENNEKQMRQLSVIPPMMFDAEQRRVKFINMNGLMEDPMKVYKDRQFMNVWTDHEKEIFKEKFVQHPKNFGLIASYLERKNVPDCVLYYYLTKKNENYKALVRRNYGKRRGRNQQQIARPSQEEKVEEKVEEEKAEKADKKDEEKKDEEEKDEKEESKENTKEKDKTEVATEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAQANAAAAAATEEPPPPLPPPPEPSSTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQCKNFYFNYKRRHNLDSLLQQHKQKSSRRPREERDVSQCESVASTVSAQEDEDIEASNEEENPEDSEGAENSSDTESAPSPTPAETAKPTEETPSESAASKMTTEAAAEQESTVKPAASTSPSLTSQGVSTAESQTSEPQVKEEINTEAEEPMEVDSRSHPVEAKPVLNLPVHTKVEPVETEMRLPENIQVKIESDTKEREMEKPKEKSEPEEMDYSLSQQVNSARQESHSDNDSSATCSADEEVDGEPDRQGIFRESKPSLLNPAGSILVSPTIKQGQMDLQQLHHRAAVIPPMVSCSPCTVPVGTPVSGYALYQRHIKAMHESALLEEQRQRQEQLDMEYRSSVSPCGTSKSPNVEWEGKPVAYMPYAEVKRAIEQEAQVQTTATRSASPYRLSPREVNKASPQPDMNAARYSVPPVLQPAPHQVITNIPEGVRLPTTRPTRPPPPLIPSSKTSVPSEKPSFIMGGSISQGTPGTYLTSHSQASYTQETAKPSVGSISLGLPRQQESAKSASLPYIKQEEFSPRSQNSQPEGLLVRAQHEGVVRGTTTIQEGSITRGTPTNKVSVETIPSLRGSITQGTPALSQSGIAADALLKGTITRLATEDSSPEKCREEASAKGHVIYEGKSGHILSYDAIKNVREGTRSPRTAHEISLKRSYDTMEGNIKQGMSMRESPVSAPLEGLICRALPRGSPHAELKERTVLSGSIMQGTPRATSESFEEGLKYPKQIKRESPPIRAFEGAITKGKPYDGVTTIKEMGRSIHEIPRQDLLSQESRKTPEIVQTARPIIEGSISQGTPIKYESNSGQSAIKHNVKSLITGPSKLPRGMPQLEMVPENVKVVERGKYEDVKTGDAVRSRHTSVVSSGPSVLRSTLHETPKSQLSPGIYDDTNARRTPVNYQSPMSRSSPMMNRVSEAGISSGKSANHERKNTLTPTQRESVPAKSPVPGVDPVVAHSPFDPHHRGATPEVYRSHLPPHLDPAMPFHRALDPAAAAYLFQRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLRPDVTRGLSPREQTLALPYAGARGIIDLNNMAPTILVPHPGGTSTPPMERITYIPGTQLTFPPRPYNPASLSPGHPTHLAASAAANAEREREREREKERERERERERERERERERERERITSVPAELYLRPGAEQPGRPGSHGYVRSPSPSVRSQENILQQRPSIFQGTNGTSVITPLDPAAQLRIMQLTPGAPSITQGLPASRYNTAADALAALVDAAASAPQMEVAKGKDTKHEGTRIEENVGRRSAVVTEQQQMEQKTLEVEKRAVQCPYTSANFSGGKSQGQSSTVVYSEAGKEKGPPPKSRYEEELRTRGKTTITAANFIDVIITRQIASDKDARDRGSQSSDSSSSLSSHRYEAPGDAIEVISPANSPIPTQEKLQPYQQETPKPSQAESDPNRQYEGPIHRYRAQQEPPPSPQQPPPPSSQAEGMAHVPRTHRLITLADHICQIITQDFARNQAASQASLQPPTTTFQNSTPAPTPVSTRAKTSSRYSPEAQSQPVHHQRPGARVSPENLSDKSRGRPGKSPERSHVSSEPYEPISPPQVPVVHEKQENVLLLSQRAEPTEQRTDSRSPGSISYLPSFFTKLENTSPMVKSKKQEIFRKLNSSGGGDSDMATAQPGTEIFNLPAVTTSGAVSSRGHSFADPASNLGLEDIIRKALMGNFDDKSEDHGVVMSQSIAVAPGNSSAVVSASNETRREEANPSPNSGGAVSKQKLIGKSNSRKSKSPIPGQGYLGTERPSSVSSVHSEGDYHRQTPVWAWEDRPSSTGEKCRFSFSLMN", "length": 2485, "header": "tr|A0A8V1ANJ9-1|A0A8V1ANJ9_CHICK Computationally mapped isoform of Nuclear receptor corepressor 1 OS=Gallus gallus OX=9031 GN=NCOR1 PE=1 SV=1 CANONICAL=A0A8V1AKD2-1" }, "locus": { "chromosome": "19", "start_pos": 6993528, "end_pos": 6952041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071922.1", "url": "https://www.ensembl.org/id/ENSGALT00010071922.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044612.1", "url": "https://www.ensembl.org/id/ENSGALP00010044612.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1688, "start_aa": "Thr", "end_pos": 1688, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1688", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2203, "start_aa": "Thr", "end_pos": 2203, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2203", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 765, "start_aa": "Thr", "end_pos": 765, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr765", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-2173795", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173795", "resource": "Reactome", "description": "Downregulation of SMAD2/3:SMAD4 transcriptional activity" }, { "id": "R-GGA-350054", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-350054", "resource": "Reactome", "description": "Notch-HLH transcription pathway" }, { "id": "R-GGA-381340", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381340", "resource": "Reactome", "description": "Transcriptional regulation of white adipocyte differentiation" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" }, { "id": "R-GGA-400206", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-400206", "resource": "Reactome", "description": "Regulation of lipid metabolism by PPARalpha" }, { "id": "R-GGA-9029569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9029569", "resource": "Reactome", "description": "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" }, { "id": "R-GGA-9841922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9841922", "resource": "Reactome", "description": "MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "negative regulation of fatty acid metabolic process", "id": "GO:0045922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "negative regulation of glycolytic process", "id": "GO:0045820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045820", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "negative regulation of JNK cascade", "id": "GO:0046329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046329", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "spindle assembly", "id": "GO:0051225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "negative regulation of androgen receptor 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKD2" } ], "pmid": "" }, { "name": "nuclear receptor binding", "id": "GO:0016922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016922", "evidence": [ { "database": "UniProtKB", 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKF1-1", "uniprot_ac": "A0A8V1AKF1", "uniprot_id": "A0A8V1AKF1_CHICK", "mass": { "chemical_mass": 15893.0, "monoisotopic_mass": 15893.0 }, "refseq": { "ac": "XP_024997162", "name": "transmembrane protein 203", "summary": "", "url": 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Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997162.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997162" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM203", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF1", "locus": { "chromosome": "17", "start_pos": 1624107, "end_pos": 1625812, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028924", "url": "https://www.ensembl.org/id/ENSGALG00010028924" } ] } } ], "crossref": [ { "id": "A0A8V1AKF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22816", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22816", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112529981", "url": "https://www.ncbi.nlm.nih.gov/gene/112529981", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:112529981", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112529981", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LNTYFCA", "url": "https://omabrowser.org/oma/group/LNTYFCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKF1", "url": "https://www.orthodb.org/?gene=A0A8V1AKF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10269", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10269", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997162", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFSLRELVQWLGFATFEIFLHGLALLVFSVLLVLKVDSEVSPLSWWVVFVPFFVADGLSTYFTAIVSVRLFQDGEKRLAVLRLFWILTILSLKFVFEMLLCQKLVERTRELWYGLIMSPVFILLQLLMIRACRVN", "length": 136, "header": "tr|A0A8V1AKF1-1|A0A8V1AKF1_CHICK Isoform 1 of Transmembrane protein 203 OS=Gallus gallus OX=9031 GN=TMEM203 PE=4 SV=1 CANONICAL=A0A8V1AKF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF1/entry#A0A8V1AKF1-1", "sequence": { "sequence": "MLFSLRELVQWLGFATFEIFLHGLALLVFSVLLVLKVDSEVSPLSWWVVFVPFFVADGLSTYFTAIVSVRLFQDGEKRLAVLRLFWILTILSLKFVFEMLLCQKLVERTRELWYGLIMSPVFILLQLLMIRACRVN", "length": 136, "header": "tr|A0A8V1AKF1-1|A0A8V1AKF1_CHICK Isoform 1 of Transmembrane protein 203 OS=Gallus gallus OX=9031 GN=TMEM203 PE=4 SV=1 CANONICAL=A0A8V1AKF1-1" }, "locus": { "chromosome": "17", "start_pos": 1625707, "end_pos": 1625300, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069976.1", "url": "https://www.ensembl.org/id/ENSGALT00010069976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043102.1", "url": "https://www.ensembl.org/id/ENSGALP00010043102.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:112529981", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112529981", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5B9-1", "protein_name": "Transmembrane protein 203", "gene_name": "TMEM203", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLFSLRELVQWLGFATFEIFVHLLALLVFSVLLALRVDGLAPGLSWWNVFVPFFAADGLSTYFTTIVSVRLFQDGEKRLAVLRLFWVLTVLSLKFVFEMLLCQKLVEQTRELWFGLITSPVFILLQLLMIRACRVN", "length": 136 }, "evidence": [ { "id": "A0A8V1AKF1", "url": "https://omabrowser.org/oma/group/A0A8V1AKF1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8R235-1", "protein_name": "Transmembrane protein 203", "gene_name": "Tmem203", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFSLRELVQWLGFATFEIFVHLLALLVFSVLLALRVDGLTPGLSWWNVFVPFFAADGLSTYFTTIVSVRLFQDGEKRLAVLRLFWVLTVLSLKFVFEMLLCQKLVEQTRELWFGLITSPVFILLQLLMIRACRVN", 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} ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF1" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"isoforms": [ { "isoform_ac": "A0A8V1AKF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKF8/entry#A0A8V1AKF8-1", "sequence": { "sequence": "MCVRMRRIGAPACIPPCGHQPAARVFQCATCRLVDCQFPVDCPVQDVWVHEDEAITLHCDVPFAVPPELQVTWMFAKDIRTQDLALFEELQRGIGEPPSLTVQDPTLGTIACRLGAASETLARKYFYLNVSGGSVEAEQELQARFRAVLRWPQGRAPLHLTTSLQLGLVLGVAGLVLLLLLLLASWRCCRKSPEPPRPP", "length": 199, "header": "tr|A0A8V1AKF8-1|A0A8V1AKF8_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107054772 PE=4 SV=1 CANONICAL=A0A8V1AKF8-1" }, "locus": { "chromosome": "19", "start_pos": 531832, "end_pos": 529133, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071297.1", "url": "https://www.ensembl.org/id/ENSGALT00010071297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043988.1", "url": "https://www.ensembl.org/id/ENSGALP00010043988.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101747587", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1", "locus": {} } ], "crossref": [ { "id": "A0A8V1AKG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKG1", "url": "https://www.orthodb.org/?gene=A0A8V1AKG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALZ7", "url": "https://www.orthodb.org/?gene=A0A8V1ALZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANK7", "url": "https://www.orthodb.org/?gene=A0A8V1ANK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AKG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPQQQALHPGKGWNHLCSQSSHKIRCSIFSAATFLTAAPISADLATVWSSRFTATPDPSAPSEILGLLRVSALCRRYQGPLCSWKRDWRGREVNMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY", "length": 400, "header": "tr|A0A8V1AKG1-1|A0A8V1AKG1_CHICK Isoform 1 of Ubiquitin B OS=Gallus gallus OX=9031 GN=LOC101747587 PE=3 SV=1 CANONICAL=A0A8V1AKG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1/entry#A0A8V1AKG1-1", "sequence": { "sequence": "MCPQQQALHPGKGWNHLCSQSSHKIRCSIFSAATFLTAAPISADLATVWSSRFTATPDPSAPSEILGLLRVSALCRRYQGPLCSWKRDWRGREVNMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY", "length": 400, "header": "tr|A0A8V1AKG1-1|A0A8V1AKG1_CHICK Isoform 1 of Ubiquitin B OS=Gallus gallus OX=9031 GN=LOC101747587 PE=3 SV=1 CANONICAL=A0A8V1AKG1-1" }, "locus": { "chromosome": "19", "start_pos": 7071859, "end_pos": 7068308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071936.1", "url": "https://www.ensembl.org/id/ENSGALT00010071936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044626.1", "url": "https://www.ensembl.org/id/ENSGALP00010044626.1" } ] } }, { "isoform_ac": "A0A8V1ALZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1/entry#A0A8V1ALZ7-1", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPMTPLRM", "length": 101, "header": "tr|A0A8V1ALZ7-1|A0A8V1ALZ7_CHICK Computationally mapped isoform of Ubiquitin B OS=Gallus gallus OX=9031 GN=LOC101747587 PE=3 SV=1 CANONICAL=A0A8V1AKG1-1" }, "locus": { "chromosome": "19", "start_pos": 7071704, "end_pos": 7070945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071933.1", "url": "https://www.ensembl.org/id/ENSGALT00010071933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044623.1", "url": "https://www.ensembl.org/id/ENSGALP00010044623.1" } ] } }, { "isoform_ac": "A0A8V1ANK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1/entry#A0A8V1ANK7-1", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY", "length": 229, "header": "tr|A0A8V1ANK7-1|A0A8V1ANK7_CHICK Computationally mapped isoform of Ubiquitin B OS=Gallus gallus OX=9031 GN=LOC101747587 PE=3 SV=1 CANONICAL=A0A8V1AKG1-1" }, "locus": { "chromosome": "19", "start_pos": 7071859, "end_pos": 7070945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071935.1", "url": "https://www.ensembl.org/id/ENSGALT00010071935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044625.1", "url": "https://www.ensembl.org/id/ENSGALP00010044625.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG1" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 171, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKH3-1", "uniprot_ac": "A0A8V1AKH3", "uniprot_id": "A0A8V1AKH3_CHICK", "mass": { "chemical_mass": 85177.0, "monoisotopic_mass": 85177.0 }, "refseq": { "ac": "XP_024997193", "name": "rab-like protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997193" }, "gene_names": [ { "name": "RABL6", "type": "recommended", "evidence": [ { "id": "A0A8V1AKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3" } ] }, { "name": "RABL6", "type": "synonym", "evidence": [ { "id": "XP_024997193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997193" } ] } ], "protein_names": [ { "name": "Rab-like protein 6", "type": "recommended", "evidence": [ { "id": "A0A8V1AKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1AKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein Parf", "type": "synonym", "evidence": [ { "id": "A0A8V1AKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3/entry#names_and_taxonomy" } ] }, { "name": "Rab-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AKH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3/entry#names_and_taxonomy" } ] }, { "name": "rab-like protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_024997193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997193" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997193" } ] }, { "annotation": "Small GTPase involved in the regulation of cell growth and survival. Promotes cellular proliferation. May reduce growth inhibitory activity of CDKN2A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3#function" }, { "database": "UniProtKB", "id": "ARBA00094275", "url": "https://www.uniprot.org/uniprotkb/ARBA00094275#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RABL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3", "locus": { "chromosome": "17", "start_pos": 1256285, "end_pos": 1309899, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029147", "url": "https://www.ensembl.org/id/ENSGALG00010029147" } ] } } ], "crossref": [ { "id": "A0A8V1AKH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "417284", "url": "https://www.ncbi.nlm.nih.gov/gene/417284", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417284", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417284", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHVTYFI", "url": "https://omabrowser.org/oma/group/DHVTYFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKH3", "url": "https://www.orthodb.org/?gene=A0A8V1AKH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14932:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14932:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997193", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AKH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSALKKLVGSDQAAVRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTTLWHRLQGKKFIEEYIPTQEIQVTSIHWNYKTTDDIVKVEVWDVVDKGKCKKRGDGLKLENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDMGEHRVILPGDVRDFIDNLNRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYELFLEMMEARSRGHASPLTTNGQSPSSGSQSPIVPPSSTSTGSSSPGTPQPPQPPSTSSTVSPEPPSSFSPVPAPEAQPPHAPLPAAASPAPPAAAPPPKRSIISRLFGTSPAPEPSPPQPDAAAAAPPHPAAPAKVQSVEDFVPDDSLDHSFLEDSAPQKDKGRPQTKHRVDSESDGETPGGNPMVAGFQDDLDLDDKIPSRAVLATERVPSKNITLSSEEEEEEEAKDSRVTLIPDESIDTEREKKRSSRNSVKPQSEAVLTKATDPKPPDSLPPHSGSERSSSSKLGASLPTAAATPAVQASKTTSQSKGHALKQKVVKEEKPEESDSDQEGPIATQMLSFVMDDPDFESEESDSQRKKMDEFPVREDLSEISDDDTSLAKPPQPVKSTVHSFKLKNDSDLFGLGLEETGPKESSEEDKHASKEKKKKKKKSKEEEEKSVKKKSKHKKGKEKEESKEEKDRKKKKKRSKEKNNEIDELEAFLGGGGASMSKPRGGGDYEEL", "length": 772, "header": "tr|A0A8V1AKH3-1|A0A8V1AKH3_CHICK Isoform 1 of Rab-like protein 6 OS=Gallus gallus OX=9031 GN=RABL6 PE=1 SV=1 CANONICAL=A0A8V1AKH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3/entry#A0A8V1AKH3-1", "sequence": { "sequence": "MFSALKKLVGSDQAAVRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTTLWHRLQGKKFIEEYIPTQEIQVTSIHWNYKTTDDIVKVEVWDVVDKGKCKKRGDGLKLENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDMGEHRVILPGDVRDFIDNLNRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYELFLEMMEARSRGHASPLTTNGQSPSSGSQSPIVPPSSTSTGSSSPGTPQPPQPPSTSSTVSPEPPSSFSPVPAPEAQPPHAPLPAAASPAPPAAAPPPKRSIISRLFGTSPAPEPSPPQPDAAAAAPPHPAAPAKVQSVEDFVPDDSLDHSFLEDSAPQKDKGRPQTKHRVDSESDGETPGGNPMVAGFQDDLDLDDKIPSRAVLATERVPSKNITLSSEEEEEEEAKDSRVTLIPDESIDTEREKKRSSRNSVKPQSEAVLTKATDPKPPDSLPPHSGSERSSSSKLGASLPTAAATPAVQASKTTSQSKGHALKQKVVKEEKPEESDSDQEGPIATQMLSFVMDDPDFESEESDSQRKKMDEFPVREDLSEISDDDTSLAKPPQPVKSTVHSFKLKNDSDLFGLGLEETGPKESSEEDKHASKEKKKKKKKSKEEEEKSVKKKSKHKKGKEKEESKEEKDRKKKKKRSKEKNNEIDELEAFLGGGGASMSKPRGGGDYEEL", "length": 772, "header": "tr|A0A8V1AKH3-1|A0A8V1AKH3_CHICK Isoform 1 of Rab-like protein 6 OS=Gallus gallus OX=9031 GN=RABL6 PE=1 SV=1 CANONICAL=A0A8V1AKH3-1" }, "locus": { "chromosome": "17", "start_pos": 1309700, "end_pos": 1257289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070436.1", "url": "https://www.ensembl.org/id/ENSGALT00010070436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043127.1", "url": "https://www.ensembl.org/id/ENSGALP00010043127.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 567, "start_aa": "Thr", "end_pos": 567, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr567", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417284", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417284", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q08DA0-1", "protein_name": "Rab-like protein 6", "gene_name": "RABL6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFSALKKLVGSEQAPGRDRNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGKKFVEEYIPTQEIQVTSIHWSYKTTDDVVKVEVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDVLDHLDRPPGSSYFRYAESSMKNSFGLKYLHRFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYDIFLEMMEARSRGHASPLTTSGQSPSSGSQSPVVPPSTVSTGSSSPSTPQPVLQPPLQAPPAPPAPAEAPPLPAAPPRRSIIARLFGSTPATEAAPPPPEPTPAAEASQKVQNVEDFVPEDSLDGSFLEDTVPAKDEKRLGARGPQDSDSDRETQAGNPMVAGFQDDVDLEDKPPSRPLPPTGPVPSEDITLSSEEEAEEGAGHPKAAVLAPQKCPEPETRRSSTKALGPPRDAAPRAAKPRPEGPSGKLEEGTDKPVSSESDAEGPIAAQMLSFVMDDPDFESDSDAQRRAGEFPVREDLSDLTDEDAGPVQPPAPPKPLAPSFRLKDDSDLFGLGLEEPGREDSSEQDKEGRPPAKEKKKKKKKGREEEDKAAKKRSKHKKSRERADDKGRDERRRRPRGPQRTALDELEAFLGGGAPSGPLRGGGDYEAL", "length": 701 }, "evidence": [ { "id": "A0A8V1AKH3", "url": "https://omabrowser.org/oma/group/A0A8V1AKH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3YEC7-1", "protein_name": "Rab-like protein 6", "gene_name": "RABL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGGGAPGGRHPGGGDYEEL", "length": 729 }, "evidence": [ { "id": "A0A8V1AKH3", "url": "https://omabrowser.org/oma/group/A0A8V1AKH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U3K5-1", "protein_name": "Rab-like protein 6", "gene_name": "Rabl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSALKKLVGSEQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGKKFVEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGKCKKRGDGLKTENDPQEAESELALDAEFLDVYKNCNGVVMMFDITKQWTFNYVLRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIEHLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYSIFLEMMEARSRGHASPLAANGQSPSSGSQSPVVPPSAVSTGSSSPSTPQPAPQLSLGVSSTCPSAPSPVPSLEAMPSSVHSSAPAPTPAPAPAPAQRRSIISRLFGTSPAAEVTPSPPEPAPALEAPARVQNVEDFVPEDGLDRSFLEDTSVPKDKKVGAKGPQQDSDSDDGEALGGNPMVAGFQDDVDIEDQTHGKSLLPSDPMPSKNISLSSEEEAEGLAGHPRVAPQQCSEPETKWSSTKVSHPQKKRAPTRGTPPWSDGLTTDDSERPQEGKDKQVSSESDPEGPIAAQMLSFVMDDPDFESDESDTQRRMGRFPVREDLSDVTDEDTGPAQPPPPSKLPGAFRLKNDSDLFGLGLEEMGPKESSDEDRDSKLPSKEKKKKKKKSKEEEEKTTKKKSKHKKSKDKEEGKEDRKKKRKPPRSKEQKAADELEAFLGGGAPGSRHPGGGDYEEL", "length": 725 }, "evidence": [ { "id": "A0A8V1AKH3", "url": "https://omabrowser.org/oma/group/A0A8V1AKH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKJ4-1", "uniprot_ac": "A0A8V1AKJ4", "uniprot_id": "A0A8V1AKJ4_CHICK", "mass": { "chemical_mass": 62232.0, "monoisotopic_mass": 62232.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Scavenger receptor cysteine rich family member with 4 domains", "type": "synonym", "evidence": [ { "id": "A0A8V1AKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AKJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AKJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPGSCMACGALPSSLLLLLFLLGPTGTSEPSPPPLPELRLANGPSRCQGRVEILYNGSWGTVCDDDWDIVDANVVCRQLGCGHAIAMPAPMTFGQGSGPIFLDNVDCKGQEAALSECWSHGWGVHNCYHYEDVAVVCNELSPTSASEGPTSRTATASVQNGEGDGRIRLVSGADACQGRVEIFYQGSWGTVCDDDWGLSDASVVCKQVGCGPALEYKSNAYFGYGTGHILLDNVNCEGSEPILSACYSLGWGIHNCGHHEDAGVICMGLDTSTVTSFTTSTALDYEEMLTATATAVTDGHEQPSPATKVVTTVLVTAELESGGVRLANGNGSCRGRVEVRHGGTWGTVCDDDWDFPDAQVVCRQLGCGPAVSATVLGSFGYGSGPVLLDNVGCDGHEARLADCFHLGWGQHNCGHHEDAGVVCRGADDSGDHFQEATVATTTSAPTLLEDGERPMGAGVEKRGSPWPGLAGTSPFSSTPSQCPTAGFLRLVNGSHRCEGRVEMFYLSQWGTVCDDAWDLRDAEVVCRQLGCGSAVAAWGEAHYGPGTGYIFLDNLKCKGSEPALLRCSHIRWDVHNCDHSEDASAVCSLL", "length": 591, "header": "tr|A0A8V1AKJ4-1|A0A8V1AKJ4_CHICK Isoform 1 of Scavenger receptor cysteine rich family member with 4 domains OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AKJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4/entry#A0A8V1AKJ4-1", "sequence": { "sequence": "MSPGSCMACGALPSSLLLLLFLLGPTGTSEPSPPPLPELRLANGPSRCQGRVEILYNGSWGTVCDDDWDIVDANVVCRQLGCGHAIAMPAPMTFGQGSGPIFLDNVDCKGQEAALSECWSHGWGVHNCYHYEDVAVVCNELSPTSASEGPTSRTATASVQNGEGDGRIRLVSGADACQGRVEIFYQGSWGTVCDDDWGLSDASVVCKQVGCGPALEYKSNAYFGYGTGHILLDNVNCEGSEPILSACYSLGWGIHNCGHHEDAGVICMGLDTSTVTSFTTSTALDYEEMLTATATAVTDGHEQPSPATKVVTTVLVTAELESGGVRLANGNGSCRGRVEVRHGGTWGTVCDDDWDFPDAQVVCRQLGCGPAVSATVLGSFGYGSGPVLLDNVGCDGHEARLADCFHLGWGQHNCGHHEDAGVVCRGADDSGDHFQEATVATTTSAPTLLEDGERPMGAGVEKRGSPWPGLAGTSPFSSTPSQCPTAGFLRLVNGSHRCEGRVEMFYLSQWGTVCDDAWDLRDAEVVCRQLGCGSAVAAWGEAHYGPGTGYIFLDNLKCKGSEPALLRCSHIRWDVHNCDHSEDASAVCSLL", "length": 591, "header": "tr|A0A8V1AKJ4-1|A0A8V1AKJ4_CHICK Isoform 1 of Scavenger receptor cysteine rich family member with 4 domains OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AKJ4-1" }, "locus": { "chromosome": "19", "start_pos": 4713409, "end_pos": 4706425, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070461.1", "url": "https://www.ensembl.org/id/ENSGALT00010070461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043152.1", "url": "https://www.ensembl.org/id/ENSGALP00010043152.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 151, "start_aa": "Thr", "end_pos": 151, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr151", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 479, "start_aa": "Thr", "end_pos": 479, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr479", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ4" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 139, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 151, 479 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 331, "end_pos": 333 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKK4-1", "uniprot_ac": "A0A8V1AKK4", "uniprot_id": "A0A8V1AKK4_CHICK", "mass": { "chemical_mass": 40458.0, "monoisotopic_mass": 40458.0 }, "refseq": { "ac": "XP_004946747", "name": "spermatogenesis-associated protein 22 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946747" }, "gene_names": [ { "name": "SPATA22", "type": "recommended", "evidence": [ { "id": "A0A8V1AKK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4" } ] }, { "name": "SPATA22", "type": "synonym", "evidence": [ { "id": "XP_004946747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946747" } ] } ], "protein_names": [ { "name": "Spermatosis associated 22", "type": "synonym", "evidence": [ { "id": "A0A8V1AKK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-associated protein 22 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004946747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946747" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946747.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946747" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPATA22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4", "locus": { "chromosome": "19", "start_pos": 7201364, "end_pos": 7195363, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029751", "url": "https://www.ensembl.org/id/ENSGALG00010029751" } ] } } ], "crossref": [ { "id": "A0A8V1AKK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "771958", "url": "https://www.ncbi.nlm.nih.gov/gene/771958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771958", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771958", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AKK4", "url": "https://www.orthodb.org/?gene=A0A8V1AKK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35258:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35258:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004946747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRSSADASTRSTAGCLPVPLFNQKKRTRQPLTSNPLKNEPGSSSATHDSFSSSLGWGAANPEVDELQKAANEGADDHMAPSLMKPPNASKSNSVKAGRNLYAFRTEEKTPSTKIWNRNECTPASNRTGSNSDSGTTQKFENRSNNWKTVQQQKMPDSSNASQHIRTPETSQTHSTKGQRPVKPNTTSRNLQDSGLAYKFNSNSQQNSMNEKQFDCVPEDKSQDISSFQLKLKEKRNSLRIISAVIESMKHWSQYTYKTTLLFEVLGTLDSAVTSGAYGAKNFLLRDGTESLPCVFYEIDRELPRLIRGRVLRCMGNYDAKRNIFKCVSVRPATIPEQNTFQEFVKIADVEMTAYVKTMNEI", "length": 362, "header": "tr|A0A8V1AKK4-1|A0A8V1AKK4_CHICK Isoform 1 of Spermatosis associated 22 OS=Gallus gallus OX=9031 GN=SPATA22 PE=4 SV=1 CANONICAL=A0A8V1AKK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4/entry#A0A8V1AKK4-1", "sequence": { "sequence": "MKRSSADASTRSTAGCLPVPLFNQKKRTRQPLTSNPLKNEPGSSSATHDSFSSSLGWGAANPEVDELQKAANEGADDHMAPSLMKPPNASKSNSVKAGRNLYAFRTEEKTPSTKIWNRNECTPASNRTGSNSDSGTTQKFENRSNNWKTVQQQKMPDSSNASQHIRTPETSQTHSTKGQRPVKPNTTSRNLQDSGLAYKFNSNSQQNSMNEKQFDCVPEDKSQDISSFQLKLKEKRNSLRIISAVIESMKHWSQYTYKTTLLFEVLGTLDSAVTSGAYGAKNFLLRDGTESLPCVFYEIDRELPRLIRGRVLRCMGNYDAKRNIFKCVSVRPATIPEQNTFQEFVKIADVEMTAYVKTMNEI", "length": 362, "header": "tr|A0A8V1AKK4-1|A0A8V1AKK4_CHICK Isoform 1 of Spermatosis associated 22 OS=Gallus gallus OX=9031 GN=SPATA22 PE=4 SV=1 CANONICAL=A0A8V1AKK4-1" }, "locus": { "chromosome": "19", "start_pos": 7200316, "end_pos": 7196168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071977.1", "url": "https://www.ensembl.org/id/ENSGALT00010071977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044666.1", "url": "https://www.ensembl.org/id/ENSGALP00010044666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771958", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771958", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of meiotic cell cycle", "id": "GO:0051445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051445", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4" } ], "pmid": "" }, { "name": "meiotic DNA repair synthesis", "id": "GO:0000711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4" } ], "pmid": "" }, { "name": "gamete generation", "id": "GO:0007276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKK6-1", "uniprot_ac": "A0A8V1AKK6", "uniprot_id": "A0A8V1AKK6_CHICK", "mass": { "chemical_mass": 29284.0, "monoisotopic_mass": 29284.0 }, "refseq": {}, "gene_names": [ { "name": "CYB5D2", "type": "recommended", "evidence": [ { "id": "A0A8V1AKK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6" } ] } ], "protein_names": [ { "name": "Neuferricin", "type": "recommended", "evidence": [ { "id": "A0A8V1AKK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome b5 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AKK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Heme-binding protein which promotes neuronal but not astrocyte differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6#function" }, { "database": "UniProtKB", "id": "ARBA00037690", "url": "https://www.uniprot.org/uniprotkb/ARBA00037690#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYB5D2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6", "locus": { "chromosome": "19", "start_pos": 3688995, "end_pos": 3693555, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029164", "url": "https://www.ensembl.org/id/ENSGALG00010029164" } ] } } ], "crossref": [ { "id": "A0A8V1AKK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKK6", "url": "https://www.orthodb.org/?gene=A0A8V1AKK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10281:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRGAVVVSVLCLGAAWLLGRGFDPRSWLQPRSRLLSAAELGRYRGAPGDPGLYLALLGRVFDVQPGRKHYGPGGAYSGLAGVTAPFATGRDATRAFATGDFTPSGLVDDVSALSPAEMLTIQSWLSFYSTNYACVGKLVGRFYDENGAPTEALRQAEAAIEEGLKFKAESDQWKERFPPCNSEWSSAKGSRFWCSRQSGGVNRDWTGVPRKLYRPGLRGSHCVCVRTNGPPWGQQGSAQHSDRGDLDNPHLQEYDGCHPRAEQCILST", "length": 269, "header": "tr|A0A8V1AKK6-1|A0A8V1AKK6_CHICK Isoform 1 of Neuferricin OS=Gallus gallus OX=9031 GN=CYB5D2 PE=3 SV=1 CANONICAL=A0A8V1AKK6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6/entry#A0A8V1AKK6-1", "sequence": { "sequence": "MRRGAVVVSVLCLGAAWLLGRGFDPRSWLQPRSRLLSAAELGRYRGAPGDPGLYLALLGRVFDVQPGRKHYGPGGAYSGLAGVTAPFATGRDATRAFATGDFTPSGLVDDVSALSPAEMLTIQSWLSFYSTNYACVGKLVGRFYDENGAPTEALRQAEAAIEEGLKFKAESDQWKERFPPCNSEWSSAKGSRFWCSRQSGGVNRDWTGVPRKLYRPGLRGSHCVCVRTNGPPWGQQGSAQHSDRGDLDNPHLQEYDGCHPRAEQCILST", "length": 269, "header": "tr|A0A8V1AKK6-1|A0A8V1AKK6_CHICK Isoform 1 of Neuferricin OS=Gallus gallus OX=9031 GN=CYB5D2 PE=3 SV=1 CANONICAL=A0A8V1AKK6-1" }, "locus": { "chromosome": "19", "start_pos": 3693541, "end_pos": 3690431, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070476.1", "url": "https://www.ensembl.org/id/ENSGALT00010070476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043167.1", "url": "https://www.ensembl.org/id/ENSGALP00010043167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK6" }, { "id": "SM01117", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01117" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytochrome b5 heme-binding", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 140, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKK8-1", "uniprot_ac": "A0A8V1AKK8", "uniprot_id": "A0A8V1AKK8_CHICK", "mass": { "chemical_mass": 95377.0, "monoisotopic_mass": 95377.0 }, "refseq": { "ac": "NP_001092080", "name": "Fanconi anemia core complex-associated protein 100", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080" }, "gene_names": [ { "name": "FAAP100", "type": "recommended", "evidence": [ { "id": "A0A8V1AKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8" } ] }, { "name": "C17orf70", "type": "synonym", "evidence": [ { "id": "NP_001092080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080" } ] }, { "name": "C18H17orf70", "type": "synonym", "evidence": [ { "id": "NP_001092080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080" } ] }, { "name": "FAAP100", "type": "synonym", "evidence": [ { "id": "NP_001092080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080" } ] } ], "protein_names": [ { "name": "FancA associated protein of 100 kDa", "type": "synonym", "evidence": [ { "id": "NP_001092080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080" } ] }, { "name": "Fanconi anemia core complex associated protein 100", "type": "synonym", "evidence": [ { "id": "A0A8V1AKK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8/entry#names_and_taxonomy" } ] }, { "name": "Fanconi anemia core complex-associated protein 100", "type": "synonym", "evidence": [ { "id": "NP_001092080", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.16581.1, SRR13267655.12056.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000317.1. On Dec 9, 2021 this sequence version replaced NP_001092080.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001092080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAAP100", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8", "locus": { "chromosome": "18", "start_pos": 9816678, "end_pos": 9809919, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029518", "url": "https://www.ensembl.org/id/ENSGALG00010029518" } ] } } ], "crossref": [ { "id": "A0A8V1AKK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100049617", "url": "https://www.ncbi.nlm.nih.gov/gene/100049617", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100049617", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100049617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RVHHAVI", "url": "https://omabrowser.org/oma/group/RVHHAVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKK8", "url": "https://www.orthodb.org/?gene=A0A8V1AKK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14890:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14890:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001092080", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092080", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQVGHRVDYLAGFCCPVGGLVAGKPRVLCHESEIYLCNGSEFVYIYDQEGKVLKAVYRCPDQVWHVELLPLTRQLYILCAHSGIYCVSLDQQSRLMEQTDGDGQESNCPSGVFPVDSDACIFPDSSLCMFTLLNNFVITLSQAHGKWWMKLHELPRPEQDSPPYRQVSEVGFCPGPAPSEEGDGAPSRFLPVLCCASSPGTAGSGEGPWCSGGFVLEEPLFSLLFGIDAAMLESPMILCGFPDGQLCAVPLKALSSPPADGCHDVSGQDPPVKILHHLEEPIVFIGALRTERRAAEEEEEEEEDAEDDALFGNAGCDCVVAVGHYGKMVAVKADQRDETTVPELREYYLRGPILCAACGSGSRMYYSTHSDISAVDLDWVSESSDPEDAESCGGVLPPVLSPASLSICSVVALSLSSRASEGESELLALSAKGRLMTCGLCSPEDADVELTPAEAGRRIKALLSGIGNTSERVSFLKKAVDQKNRALASLNQVMNVSAALLSGQEGQKPIACTVTANWSCLLLRDTVTISCLLENCSEYSLEQGWTLCVQLLASPCALEEESVDSATTFTFPIDQLLPGTKRELTLPLSSAADTKLDLPLTISCALYYSLRDILGSGSDSPEALDDLLPDDSPILSPDREGICLPLSECTIDMLQCLRFESSTPRPDASPKAASLPAPQDPVETFLKASKEQPEPEAGTASEQPCATGEGGMPPSAASIRVSSELLKNALKTSGSDVPLSCATLRWLLAENAAATTLSSEEVTSVCGAAPDGGEVQLIIREVAMNDLSPAGPIQAVEILMESPSLAHTCRMHHAVIRRMQALVLEQAAQGSGPPDLRMQYLRQIQTNHEMLLKEAQSLRDHSPLTEEDTEKLLHIYQQLRNPSLVLL", "length": 888, "header": "tr|A0A8V1AKK8-1|A0A8V1AKK8_CHICK Isoform 1 of Fanconi anemia core complex associated protein 100 OS=Gallus gallus OX=9031 GN=FAAP100 PE=4 SV=1 CANONICAL=A0A8V1AKK8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8/entry#A0A8V1AKK8-1", "sequence": { "sequence": "MAQVGHRVDYLAGFCCPVGGLVAGKPRVLCHESEIYLCNGSEFVYIYDQEGKVLKAVYRCPDQVWHVELLPLTRQLYILCAHSGIYCVSLDQQSRLMEQTDGDGQESNCPSGVFPVDSDACIFPDSSLCMFTLLNNFVITLSQAHGKWWMKLHELPRPEQDSPPYRQVSEVGFCPGPAPSEEGDGAPSRFLPVLCCASSPGTAGSGEGPWCSGGFVLEEPLFSLLFGIDAAMLESPMILCGFPDGQLCAVPLKALSSPPADGCHDVSGQDPPVKILHHLEEPIVFIGALRTERRAAEEEEEEEEDAEDDALFGNAGCDCVVAVGHYGKMVAVKADQRDETTVPELREYYLRGPILCAACGSGSRMYYSTHSDISAVDLDWVSESSDPEDAESCGGVLPPVLSPASLSICSVVALSLSSRASEGESELLALSAKGRLMTCGLCSPEDADVELTPAEAGRRIKALLSGIGNTSERVSFLKKAVDQKNRALASLNQVMNVSAALLSGQEGQKPIACTVTANWSCLLLRDTVTISCLLENCSEYSLEQGWTLCVQLLASPCALEEESVDSATTFTFPIDQLLPGTKRELTLPLSSAADTKLDLPLTISCALYYSLRDILGSGSDSPEALDDLLPDDSPILSPDREGICLPLSECTIDMLQCLRFESSTPRPDASPKAASLPAPQDPVETFLKASKEQPEPEAGTASEQPCATGEGGMPPSAASIRVSSELLKNALKTSGSDVPLSCATLRWLLAENAAATTLSSEEVTSVCGAAPDGGEVQLIIREVAMNDLSPAGPIQAVEILMESPSLAHTCRMHHAVIRRMQALVLEQAAQGSGPPDLRMQYLRQIQTNHEMLLKEAQSLRDHSPLTEEDTEKLLHIYQQLRNPSLVLL", "length": 888, "header": "tr|A0A8V1AKK8-1|A0A8V1AKK8_CHICK Isoform 1 of Fanconi anemia core complex associated protein 100 OS=Gallus gallus OX=9031 GN=FAAP100 PE=4 SV=1 CANONICAL=A0A8V1AKK8-1" }, "locus": { "chromosome": "18", "start_pos": 9816169, "end_pos": 9810534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071352.1", "url": "https://www.ensembl.org/id/ENSGALT00010071352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044043.1", "url": "https://www.ensembl.org/id/ENSGALP00010044043.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100049617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100049617", "resource": "KEGG Pathway" }, { "id": "R-GGA-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-GGA-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZNL4-1", "protein_name": "FA core complex associated protein 100", "gene_name": "Faap100", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWAVPSQVLSQNDARASAAYNLAPEQPLLNRMAGASSRVHYLSDFCCPLGGRAAGKPHVLRHDAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLATRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEDETHPYPVIHVDPDACVLPDAALCAFTVLDDVLVTLAQGPTQWKMQLFECPHAGEEPRPGGQVGEVQLSTCTPPGGVPGEPTAPCFLPVLCCVFPPDSRAPHGHPQGCGCFMLEEALFGLLFGVDASLLQSPVVLCGLPDGQLCCVALKALVTSELAPGDPKVLVKILHHLEEPVIFIGALRAEPQEEEEEEAVRELLPVENVHSDCLVALGHQGRTLAIRASWSESGNLVPELREYYLPGPVLCAACGRDGHMYHSTPSDLCVVDLTRRDSTWNPEKPDGAIGSLPSTLCPASLNICSALALCVTARAPTGGTELLVLSSKGRLITCSLDLNPEAPVPTKMAVANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSSQEGDRPISCTITTSWSRLELRDMLMATCTLDNSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVIGEALAPSDPLEVPYLEKLPLNLPKQEGVCLPLCKRTVDMLQCLRFPGVASHPAQAPSVPGPACDPVETFLKTCQGPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDGHSGFHLCSATLCWLLAENAAVDVLRAQALSSIQGIAPDGTDVNLIVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIKTMVTEQAAQGSSPPDLRMQYLQQIHANHQELLREVQTLRDQLCTEDEVSSCSTAQKLLQIYKQLRNPSLVLL", "length": 913 }, "evidence": [ { "id": "A0A8V1AKK8", "url": "https://omabrowser.org/oma/group/A0A8V1AKK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32U1W0-1", "protein_name": "Fanconi anemia core complex-associated protein 100 isoform X1", "gene_name": "faap100", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAARCSVEFLSEFSDCQSDSVRFIREDTNLFLTSGHRDVLIFSVQDRKVKTVIQFEDSVTFLDLSDDKHRLYALCKNGGLYCIPLPQQLSSSPVNKSPEPMLHVVSDDSLVLKNAGLQAFTIVKKILVTLSLDKSVWSFNLYEEPGSKPFCKLAHIQITTVTTCCLNVADKETSVSSPPVLTCIHPEGSTSVKTHQSDLHPHLEPHLFRLLFGVDAALVSSPVILCGLPDGRICCFPLLVPTLTGPRGEQRSPIRVLQSLEQPIVFIGTCISGEHGPQSLIVVGQRGKLLMVRSKPRSSEGKEADYSFNEHSVRGPVLCACVDDKRLFYSSLNDFHALQLTTSSSSEAMGTEPQLQALISNSLGVCRVIALAGPYTNPTGSVQLLALSSSGRLMRVNLPQGSEKGILSRLSSSLAGQRVKDLLASIGNVWERAESLKQKLQEKNESLKQLNQVLNICSLLLESNGKEKQSNMDTKPLISCHGAARWSSLLQKTSLTLTCVLENSSGCTLEHGWTLCFQVHSFYQHPNTESASSSYSFPLRKLDSGQKLDVTIPLESNGGLFLPVKVCCSLSFSLCALFGPEASSPGVFQLLKEAGSISATLNTLTVDWLDALRLEGSFSPNDIRCNTVSEGIQAFLRSRGVSTKHLDNISNPGPVAVVVSVSIELLKSKLHLSTTSSLESSMSVLNWLVSPEKIGSVKSPVVNAYSPDGCSVKIMAKEVTLGDFYSEGPLEALEIRVESSSVAAVCGLHHAILRRLLDLLRDSSAQYSHTRNLKAQSLCEAVRHVEVIYLFTLQLFNCMNKVLRCHHMNHYSVKVSEHFNSSPEFNMRQAMVTHKQC", "length": 838 }, "evidence": [ { "id": "A0A8V1AKK8", "url": "https://omabrowser.org/oma/group/A0A8V1AKK8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2ACJ2-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "Faap100", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGASSRVHYLSDFCCPLGGRAAGKPFVLRHEAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLAIRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEEAAPPYPVIHVDPDACVLPDAALCAFTVLDDMLVTLAQGPTQWKMQLFERPCAGEEPLPRGQIGEVELSTCTPPGGVPEKPAAPRFLPVLCCVFPPDSRAPHGHPQGCGCFTLEEALFGLLFGVDATLLQSPVILCGLPDGQLCCVVLKALVTSGLAPGDPKVLVKILHHLEEPVIFIGALRAEPHEEEAAGELLPGQHEHSDCLVALGHQGRTLAIKASWSESGNLVPELREYCLPGPVLCAACDRDGHVYHSTPSDLCVVDLTRRDSPWNPEKPDGAIGGLPSVLCPASLNICSALALCVTARAPTGSTELLALSSKGRLITCSLDLNSEAPVPAKMAMANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRPIACTITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQFPLSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRAQTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIQTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLHIYKQLRNPSLVLL", "length": 879 }, "evidence": [ { "id": "A0A8V1AKK8", "url": "https://omabrowser.org/oma/group/A0A8V1AKK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MJP8-1", "protein_name": "FA core complex associated protein 100", "gene_name": "FAAP100", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADPRPRVEYLAGFCCPLGGVAAGKPRVLCHGAEIFLSTGGEMVYVYDREGRLLIAVYKFPGQVWHLELLALRKVLYVLCARSGIYCLSLDQTTRSVSRDEEDGGDDQDREDGQVGEPPVPVIPVDPDSCVLPDASLHAFTVLDDTLVTLALGPTQWKMQLFERPSPGEDPRPGGQIGEVELSTCTPPAGSQGESAAPRFLPVLCCASPPGSRTPLGHSRSSEGVMLEGALFGLLFGADAALLESPVVLCGLPDGQLCCVIIKTLVTSMSAPGDPKALVKILHHLEEPVVFIGALRTEPLAEDMEDVHCDCLVALGHHGRTLAIKASWDEAGHLVPELREYSIPGPVLCAACDRSSHVYHSTSAGLRVVDLAQEGSPLDPTERDGAPGSLPPLLYPDNLGVGSLVTLCVSSSAPEGGAELLALSAKGRLMICHLDPHNEAPQSSRVTSAKAGKKIKQLLSGIGTVSERVSSLKKAVDQRDKALTCLNEVMNVSCALLSSREGPRPISCTISTTWSHLQLQDVLVATCLLENSSGFSLDRGWALCIQVLRSSRALDLDSAGSAITYTIPVDQLGPGGRREVTLPLGPGEDGALDLPVTVSCALFYSLREVVGRALTPQDPFKDPPSAECTPIVLPEQDGVCLPLSEHTVDMLQGLRFPSLGVPHTQALGPARDPIHTFLGTCRVPGSQPAGPESLRAKYLPPSVATIKVSAELLRAALGDSHAGVSLGCATLQWLLAENAAADIIKAQALSSVQGVAPDGTDVHLIIREATVTDLCPAGPIQAMEIQVESSSLANMCRAHHAIVGRLQRLVVEQAARGSSPPDLRLQYLHQMQANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRRLRSPSLLLL", "length": 879 }, "evidence": [ { "id": "A0A8V1AKK8", "url": "https://omabrowser.org/oma/group/A0A8V1AKK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0VG06-1", "protein_name": "Fanconi anemia core complex-associated protein 100", "gene_name": "FAAP100", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAAPRVRYLAGFCCPLGGLAAGKPRVLCHEAEVFLSTGSELVYVYDQEGGLLTAAFRFPDQVWHLELLAPRRLLYALCARRGLYCLSLDHPGRSRSTSQDDRDSEDGDQPSPVIPVDPDACILPDAALCAFTLLDSVLVTLVQGPARWKMQLFEQPCPGEDPRPGGQIGEVELSSYTPPAGVPGKPAAPHFLPVLCSVSPSGSRVPHDLLGGSGGFTLEDALFGLLFGADATLLQSPVVLCGLPDGQLCCVILKALVTSRSAPGDPNALVKILHHLEEPVIFIGALKTEPQAAEAAENFLPDEDVHCDCLVAFGHHGRMLAIKASWDESGKLVPELREYCLPGPVLCAACGGGGRVYHSTPSDLCVVDLSRGSTPLGPEQPEEGPGGLPPMLCPASLNICSVVSLSASPRTHEGGTKLLALSAKGRLMTCSLDLDSEMPGPARMTTESAGQKIKELLSGIGNISERVSFLKKAVDQRNKALTSLNEAMNVSCALLSSGTGPRPISCTTSTTWSRLQTQDVLMATCVLENSSSFSLDQGWTLCIQVLTSSCALDLDSACSAITYTIPVDQLGPGARREVTLPLGPGENGGLDLPVTVSCTLFYSLREVVGGALAPSDSEDPFLDECPSDVLPEQEGVCLPLSRHTVDMLQCLRFPGLAPPHTRAPSPLGPTRDPVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQATQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL", "length": 881 }, "evidence": [ { "id": "A0A8V1AKK8", "url": "https://omabrowser.org/oma/group/A0A8V1AKK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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CANONICAL=A0A8V1AKM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM7/entry#A0A8V1AKM7-1", "sequence": { "sequence": "GGGSPYGRGPPIPRKRFTRPSHRQPLPRVEPRTGQTGSRYPLGTPGSSQSLTPRSDGAPPLDAAWWRDPRLQVGRLTAAPRLLRLCNTLTGQNCVVEVCGEEPVGEALWRAKAWKEQLERYTACYGGVPLRLHLSLEQNGIPDSTSELRSLRLDPKDFIPTVLLYFNDDAGNATEAPTVTSSPP", "length": 184, "header": "tr|A0A8V1AKM7-1|A0A8V1AKM7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC107055082 PE=3 SV=1 CANONICAL=A0A8V1AKM7-1" }, "locus": { "chromosome": "25", "start_pos": 153572, "end_pos": 152637, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068988.1", "url": "https://www.ensembl.org/id/ENSGALT00010068988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042430.1", "url": "https://www.ensembl.org/id/ENSGALP00010042430.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { 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movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 44 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 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"exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074362" } ] }, { "name": "EVI2A", "type": "synonym", "evidence": [ { "id": "NP_001074362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074362" } ] } ], "protein_names": [ { "name": "Ecotropic viral integration site 2A", "type": "synonym", "evidence": [ { "id": "A0A8V1AKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN3/entry#names_and_taxonomy" } ] }, { "name": "protein EVI2A precursor", "type": "synonym", "evidence": [ { "id": "NP_001074362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074362" } ] }, { "name": "protein EVI2A", "type": "synonym", "evidence": [ { "id": "NP_001074362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074362" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720220.1, CF255526.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000323.1. 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"Genome Annotation" ] }, { "id": "IPR008608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776037", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776037", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THLWANN", "url": "https://omabrowser.org/oma/group/THLWANN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKN3", "url": "https://www.orthodb.org/?gene=A0A8V1AKN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15568:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15568:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05399", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05399", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001074362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTKRHGKPHSAFPLWIIFSLCLQVTANHTDYPRVTNEIWYPICQNLTCSQNIPETNTTSPPGTEFNGKSTPTAEMQTATPQPLYSTMGSNFFTSSSAQSVPDTGGPGNTSKPKITMTKETCEDNKFLILICFVIIAALVLICTFLFLSTIVIANKLSYLKKAQQGKRRPRSNGDILATNSFWPTAAGTWQRIPKETTGSDLVMQDLLSGRDAAIQTKTQDEPTESHTKDTVNKHENKETVSHKSILTNFVVEI", "length": 254, "header": "tr|A0A8V1AKN3-1|A0A8V1AKN3_CHICK Isoform 1 of Ecotropic viral integration site 2A OS=Gallus gallus OX=9031 GN=EVI2A PE=4 SV=1 CANONICAL=A0A8V1AKN3-1" }, 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"MPTDMEHTGHYLHLAFLMTTVFSLSPGTKANYTRLWANSTSSWDSVIQNKTGRNQNENINTNPITPEVDYKGNSTNMPETSHIVALTSKSEQELYIPSVVSNSPSTVQSIENTSKSHGEIFKKDVCAENNNNMAMLICLIIIAVLFLICTFLFLSTVVLANKVSSLRRSKQVGKRQPRSNGDFLASGLWPAESDTWKRTKQLTGPNLVMQSTGVLTATRERKDEEGTEKLTNKQIG", "length": 236 }, "evidence": [ { "id": "A0A8V1AKN3", "url": "https://omabrowser.org/oma/group/A0A8V1AKN3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKN7-1", "uniprot_ac": "A0A8V1AKN7", "uniprot_id": "A0A8V1AKN7_CHICK", "mass": { "chemical_mass": 97416.0, "monoisotopic_mass": 97416.0 }, "refseq": { "ac": "XP_046758233", "name": "carbohydrate-responsive element-binding protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758233" }, "gene_names": [ { "name": "MLXIPL", "type": "recommended", "evidence": [ { "id": "A0A8V1AKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7" } ] }, { "name": "ChREBP", "type": "synonym", "evidence": [ { "id": "XP_046758233", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758233" } ] }, { "name": "MLXIPL", "type": "synonym", "evidence": [ { "id": "XP_046758233", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758233" } ] } ], "protein_names": [ { "name": "MLX interacting protein like", "type": "synonym", "evidence": [ { "id": "A0A8V1AKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7/entry#names_and_taxonomy" } ] }, { "name": "carbohydrate-responsive element-binding protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046758233", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758233" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758233" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MLXIPL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7", "locus": { "chromosome": "19", "start_pos": 702127, "end_pos": 717312, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029533", "url": "https://www.ensembl.org/id/ENSGALG00010029533" } ] } } ], "crossref": [ { "id": "A0A8V1AKN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21771", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21771", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101751014", "url": "https://www.ncbi.nlm.nih.gov/gene/101751014", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADH3", "url": "https://www.orthodb.org/?gene=A0A8V1ADH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKN7", "url": "https://www.orthodb.org/?gene=A0A8V1AKN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP38", "url": "https://www.orthodb.org/?gene=A0A8V1AP38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15741", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15741", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15741:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15741:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046758233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758233", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP38", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAQLGLPGPFAQPPVGPCPDSDFDSDPEDAAAGGAGPGAAVQNPSQVIHSGHFMVSSPHHDALPHRRHRRAEPSAADPRSIDPTLTWLFECMSLEYSGKLVSPKWKNFKGQQLLCRDKIRLNNAIWRAWYIQYVEQRKNPVCGFITPLEGSEADEHRKPEAVVLEGNYWKRRIEVVMREYHKWRTYYKKRLRKSSREGELSSPKQDEDAWRPTEKWCNQLFCNVVPMLLGDEEEELGGRQHFDLDTFLSDISDTLFTMTQIPSTHQELPEDAYIGNADMIQPDLAPLQPSLDDTMEISDIFIGHRPLPAQMPLGYQEPPCFEPLYGSGGTVPASSDAPLPPSPLLQVSGTLAHDPRPPVPEPPLLTQPCPPQPSDATQLSLHGAFFGPEQPPLAPEPLTAVPGCLSPQLKPKPLLQYGFPSKCLGTEPLSLPYTAPSQAPGTPLLGSQPPFSPASAPHSKFPFTASPSPSLLAHPASPLSVPCFAQHTPGLGYAMDVVPLGYPSPAVPQHLPPAVPPGPRFATPKGPTPAERSKVKPSGTKAKRLPGPPVPSHLTVPNACLTQLLATAKQEPAFDAPHVHSPALMPASPASPQSSVPDVPAVFLPRVAQLSSVLSPGSSPSQEVPVMQAGAAPGPLRVPKAERLSPTLVCGSDWPKPGQVSPGAAPPPGTTISLHHPPSRRGRPDSSKMESRRITHISAEQKRRFNIKLGFDTLHSLVSTLSAQPSIKVSKATTLQKTAEYICKLQQERAALQDEAQRLREQIEELNSSINLCQEQLPATGVPITRQRFDQMRSMFDDYVRSSTLHNWKFWIVSFGPAPASHCPFHHTLGPLSPPSSVWDPSFSRGSVGDAWRGHAQMLRRNFCHKRATRVGINGRSLGSREATSRAELSIAT", "length": 895, "header": "tr|A0A8V1AKN7-1|A0A8V1AKN7_CHICK Isoform 1 of MLX interacting protein like OS=Gallus gallus OX=9031 GN=MLXIPL PE=4 SV=1 CANONICAL=A0A8V1AKN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7/entry#A0A8V1ADH3-1", "sequence": { "sequence": "MAEAQLGLPGPFAQPPVGPCPDSDFDSDPEDAAAGGAGPGAAVQNPSQVIHSGHFMVSSPHHDALPHRRHRRAEPSAADPRSIDPTLTWLFECMSLEYSGKLVSPKWKNFKGQQLLCRDKIRLNNAIWRAWYIQYVEQRKNPVCGFITPLEGSEADEHRKPEAVVLEGNYWKRRIEVVMREYHKWRTYYKKRLRKSSREGELSSPKQDEDAWRPTEKWCNQLFCNVVPMLLGDEEEELGGRQHFDLDTFLSDISDTLFTMTQIPSTHQELPEDAYIGNADMIQPDLAPLQPSLDDTMEISDIFIGHRPLPAQMPLGYQEPPCFEPLYGSGGTVPASSDAPLPPSPLLQPSDATQLSLHGAFFGPEQPPLAPEPLTAVPGCLSPQLKPKPLLQYGFPSKCLGTEPLSLPYTAPSQAPGTPLLGSQPPFSPASAPHSKFPFTASPSPSLLAHPASPLSVPCFAQHTPGLGYAMDVVPLGYPSPAVPQHLPPAVPPGPRFATPKGPTPAERSKVKPSGTKAKRLPGPPVPSHLTVPNACLTQLLATAKQEPAFDAPHVHSPALMPASPASPQSSVPDVPAVFLPRVAQLSSVLSPGSSPSQEVPVMQAGAAPGPLRVPKAERLSPTLVCGSDWPKPGQVSPGAAPPPGTTISLHHPPSRRGRPDSSKMESRRITHISAEQKRRFNIKLGFDTLHSLVSTLSAQPSIKVSKATTLQKTAEYICKLQQERAALQDEAQRLREQIEELNSSINLCQEQLPATGVPITRQRFDQMRSMFDDYVRSSTLHNWKFWIVSFGPAPASHCPFHHTLGPLSPPSSVWDPSFSRGSVGDAWRGHAQMLRRNFCHKRATRVGINGRSLGSREATSRAELSIAT", "length": 869, "header": "tr|A0A8V1ADH3-1|A0A8V1ADH3_CHICK Computationally mapped isoform of MLX interacting protein like OS=Gallus gallus OX=9031 GN=MLXIPL PE=4 SV=1 CANONICAL=A0A8V1AKN7-1" }, "locus": { "chromosome": "19", "start_pos": 717129, "end_pos": 703514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071390.1", "url": "https://www.ensembl.org/id/ENSGALT00010071390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044080.1", "url": "https://www.ensembl.org/id/ENSGALP00010044080.1" } ] } }, { "isoform_ac": "A0A8V1AKN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7/entry#A0A8V1AKN7-1", "sequence": { "sequence": "MAEAQLGLPGPFAQPPVGPCPDSDFDSDPEDAAAGGAGPGAAVQNPSQVIHSGHFMVSSPHHDALPHRRHRRAEPSAADPRSIDPTLTWLFECMSLEYSGKLVSPKWKNFKGQQLLCRDKIRLNNAIWRAWYIQYVEQRKNPVCGFITPLEGSEADEHRKPEAVVLEGNYWKRRIEVVMREYHKWRTYYKKRLRKSSREGELSSPKQDEDAWRPTEKWCNQLFCNVVPMLLGDEEEELGGRQHFDLDTFLSDISDTLFTMTQIPSTHQELPEDAYIGNADMIQPDLAPLQPSLDDTMEISDIFIGHRPLPAQMPLGYQEPPCFEPLYGSGGTVPASSDAPLPPSPLLQVSGTLAHDPRPPVPEPPLLTQPCPPQPSDATQLSLHGAFFGPEQPPLAPEPLTAVPGCLSPQLKPKPLLQYGFPSKCLGTEPLSLPYTAPSQAPGTPLLGSQPPFSPASAPHSKFPFTASPSPSLLAHPASPLSVPCFAQHTPGLGYAMDVVPLGYPSPAVPQHLPPAVPPGPRFATPKGPTPAERSKVKPSGTKAKRLPGPPVPSHLTVPNACLTQLLATAKQEPAFDAPHVHSPALMPASPASPQSSVPDVPAVFLPRVAQLSSVLSPGSSPSQEVPVMQAGAAPGPLRVPKAERLSPTLVCGSDWPKPGQVSPGAAPPPGTTISLHHPPSRRGRPDSSKMESRRITHISAEQKRRFNIKLGFDTLHSLVSTLSAQPSIKVSKATTLQKTAEYICKLQQERAALQDEAQRLREQIEELNSSINLCQEQLPATGVPITRQRFDQMRSMFDDYVRSSTLHNWKFWIVSFGPAPASHCPFHHTLGPLSPPSSVWDPSFSRGSVGDAWRGHAQMLRRNFCHKRATRVGINGRSLGSREATSRAELSIAT", "length": 895, "header": "tr|A0A8V1AKN7-1|A0A8V1AKN7_CHICK Isoform 1 of MLX interacting protein like OS=Gallus gallus OX=9031 GN=MLXIPL PE=4 SV=1 CANONICAL=A0A8V1AKN7-1" }, "locus": { "chromosome": "19", "start_pos": 717129, "end_pos": 703514, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071389.1", "url": "https://www.ensembl.org/id/ENSGALT00010071389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044079.1", "url": "https://www.ensembl.org/id/ENSGALP00010044079.1" } ] } }, { "isoform_ac": "A0A8V1AP38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7/entry#A0A8V1AP38-1", "sequence": { "sequence": "MAEAQLGLPGPFAQPPVGPCPDSDFDSDPEDAAAGGAGPGAAVQNPSQVIHSGHFMVSSPHHDALPHRRHRRAEPSAADPRSIDPTLTWLFECMSLEYSGKLVSPKWKNFKGQQLLCRDKIRLNNAIWRAWYIQYVEQRKNPVCGFITPLEGSEADEHRKPEAVVLEGNYWKRRIEVVMREYHKWRTYYKKRLRKSSREGELSSPKQDEDAWRPTEKWCNQLFCNVVPMLLGDEEEELGGRQHFDLDTFLSDISDTLFTMTQIPSTHQELPEDAYIGNADMIQPDLAPLQPSLDDTMEISDIFIGHRPLPAQMPLGYQEPPCFEPLYGSGGTVPASSDAPLPPSPLLQVSGTLAHDPRPPVPEPPLLTQPCPPQPSDATQLSLHGAFFGPEQPPLAPEPLTAVPGCLSPQLKPKPLLQYGFPSKCLGTEPLSLPYTAPSQAPGTPLLGSQPPFSPASAPHSKFPFTASPSPSLLAHPASPLSVPCFAQHTPGLGYAMDVVPLGYPSPAVPQHLPPAVPPGPRFATPKGPTPAERSKVKPSGTKAKRLPGPPVPSHLTVPNACLTQLLATAKQEPAFDAPHVHSPALMPASPASPQSSVPDVPAVFLPRVAQLSSVLSPGSSPSQEVPVMQAGAAPGPLRVPKAERLSPTLVCGSDWPKPGQVSPGAAPPPGTTISLHHPPSRRGRPDSSKMESRRITHISAEQKRRFNIKLGFDTLHSLVSTLSAQPSIKVSKATTLQKTAEYICKLQQERAALQDEAQRLREQIEELNSSINLCQEQLPATGVPITRQRFDQMRSMFDDYVRSSTLHNWKFWIFGVIIRPLFESFNGMVSTTSMECLTQTSLSWLEQHCSLPALRPSILSSLRQLSISTSILSDPARVPEQAARAAAGGGPS", "length": 893, "header": "tr|A0A8V1AP38-1|A0A8V1AP38_CHICK Computationally mapped isoform of MLX interacting protein like OS=Gallus gallus OX=9031 GN=MLXIPL PE=4 SV=1 CANONICAL=A0A8V1AKN7-1" }, "locus": { "chromosome": "19", "start_pos": 717129, "end_pos": 702285, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071391.1", "url": "https://www.ensembl.org/id/ENSGALT00010071391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044081.1", "url": "https://www.ensembl.org/id/ENSGALP00010044081.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 530, "start_aa": "Thr", "end_pos": 530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr530", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], 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"https://www.uniprot.org/uniprotkb/A0A8V1AKN7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKN7" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": 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"MAMMACFYCCLRARDAGGSPLGRGFGTAVPHRAAASPSRCAMADTIFGSGTGPWVCPNDRQLALRAKLQTGWSVHTFQTEKQRKMQALSPQELEVILEVIRKAEKLDVVEQQRIGRLVERLENMRKNAMGNGLSQCLLCSELLGLLGSTSVFCQDCKKKVCTKCGIETFGAQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYITPLKSSSRAGEVPSQPWQSEAAVLEAGSVGTGRSFTWARGKVVSSDSDSELSSSSQEDRPSSVGSKGSPGGKQQAGQVLSGEPGRPMRVSGSRGSAGSGQGESCHSDQAADGHNSGGGRAPGKRGTHSTTRC", "length": 336, "header": "tr|A0A8V1AKR6-1|A0A8V1AKR6_CHICK Isoform 1 of Rab effector Noc2 OS=Gallus gallus OX=9031 GN=RPH3AL PE=4 SV=1 CANONICAL=A0A8V1AKR6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6/entry#A0A8V1AKR6-1", "sequence": { "sequence": "MAMMACFYCCLRARDAGGSPLGRGFGTAVPHRAAASPSRCAMADTIFGSGTGPWVCPNDRQLALRAKLQTGWSVHTFQTEKQRKMQALSPQELEVILEVIRKAEKLDVVEQQRIGRLVERLENMRKNAMGNGLSQCLLCSELLGLLGSTSVFCQDCKKKVCTKCGIETFGAQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYITPLKSSSRAGEVPSQPWQSEAAVLEAGSVGTGRSFTWARGKVVSSDSDSELSSSSQEDRPSSVGSKGSPGGKQQAGQVLSGEPGRPMRVSGSRGSAGSGQGESCHSDQAADGHNSGGGRAPGKRGTHSTTRC", "length": 336, "header": "tr|A0A8V1AKR6-1|A0A8V1AKR6_CHICK Isoform 1 of Rab effector Noc2 OS=Gallus gallus OX=9031 GN=RPH3AL PE=4 SV=1 CANONICAL=A0A8V1AKR6-1" }, "locus": { "chromosome": "19", "start_pos": 7505434, "end_pos": 7484719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072037.1", "url": "https://www.ensembl.org/id/ENSGALT00010072037.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044727.1", "url": "https://www.ensembl.org/id/ENSGALP00010044727.1" } ] } }, { "isoform_ac": "A0A8V1AM95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6/entry#A0A8V1AM95-1", "sequence": { "sequence": "MADTIFGSGTGPWVCPNDRQLALRAKLQTGWSVHTFQTEKQRKMQALSPQELEVILEVIRKAEKLDVVEQQRIGRLVERLENMRKNAMGNGLSQCLLCSELLGLLGSTSVFCQDCKKKVCTKCGIETFGAQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYITPLKSSSRAGEVPSQPWQSEAAVLEAGSVGTGRSFTWARGKVVSSDSDSELSSSSQEDRPSSVGSKGSPGGKQQAGQVLSGEPGRPMRVSGSRGSAGSGQGESCHSDQAADGHNSGGGRAPGKRGTHSTTRC", "length": 295, "header": "tr|A0A8V1AM95-1|A0A8V1AM95_CHICK Computationally mapped isoform of Rab effector Noc2 OS=Gallus gallus OX=9031 GN=RPH3AL PE=4 SV=1 CANONICAL=A0A8V1AKR6-1" }, "locus": { "chromosome": "19", "start_pos": 7505434, "end_pos": 7484842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072039.1", "url": "https://www.ensembl.org/id/ENSGALT00010072039.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044729.1", "url": "https://www.ensembl.org/id/ENSGALP00010044729.1" } ] } }, { "isoform_ac": "A0A8V1ANT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6/entry#A0A8V1ANT7-1", "sequence": { "sequence": "MAMMACFYCCLRARDAGGSPLGRGFGTAVPHRAAASPSRCAMADTIFGSGTGPWVCPNDRQLALRAKLQTGWSVHTFQTEKQRKMQALSPQELEVILEVIRKAEKLDVVEQQRIGRLVERLENMRKNAMGNGLSQCLLCSELLGLLGSTSVFCQDCKKVWKRSGAWFYKGLPKYITPLKSSSRAGEVPSQPWQSEAAVLEAGSVGTGRSFTWARGKVVSSDSDSELSSSSQEDRPSSVGSKGSPGGKQQAGQVLSGEPGRPMRVSGSRGSAGSGQGESCHSDQAADGHNSGGGRAPGKRGTHSTTRC", "length": 307, "header": "tr|A0A8V1ANT7-1|A0A8V1ANT7_CHICK Computationally mapped isoform of Rabphilin 3A like (without C2 domains) OS=Gallus gallus OX=9031 GN=RPH3AL PE=4 SV=1 CANONICAL=A0A8V1AKR6-1" }, "locus": { "chromosome": "19", "start_pos": 7505434, "end_pos": 7484719, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072038.1", "url": "https://www.ensembl.org/id/ENSGALT00010072038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044728.1", "url": "https://www.ensembl.org/id/ENSGALP00010044728.1" } ] } }, { "isoform_ac": "A0A8V1AQ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6/entry#A0A8V1AQ55-1", "sequence": { "sequence": "MADTIFGSGTGPWVCPNDRQLALRAKLQTGWSVHTFQTEKQRKMQALSPQELEVILEVIRKAEKLDVVEQQRIGRLVERLENMRKNAMGNGLSQCLLCSELLGLLGSTSVFCQDCKKSAPNVASKPSEPRNGPFGCARSAANSERSGRGPARGSTKGCPSTSHL", "length": 164, "header": "tr|A0A8V1AQ55-1|A0A8V1AQ55_CHICK Computationally mapped isoform of Rabphilin 3A like (without C2 domains) OS=Gallus gallus OX=9031 GN=RPH3AL PE=4 SV=1 CANONICAL=A0A8V1AKR6-1" }, "locus": { "chromosome": "19", "start_pos": 7495921, "end_pos": 7484842, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072036.1", "url": "https://www.ensembl.org/id/ENSGALT00010072036.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044726.1", "url": "https://www.ensembl.org/id/ENSGALP00010044726.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772026", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" }, { "name": "positive regulation of calcium ion-dependent exocytosis", "id": "GO:0045956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" }, { "name": "calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0099502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR6" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 187, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": 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"name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AKT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AKT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AKT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SSSSILLWNSRLFARSLLTCDSAMSARSSASSSSCWILRNLESPTHPGLQLLNLLLASLQGQLLCLIQAVLQVLHRLVQVLLHPLQVGTGVSLHLLLQPQGLIPAPDLSIQAALQGLHNSEVISLQLVNFLIFLCYLPVNLRLDLVELQLEAQDLPLFMLQGGLDK", "length": 166, "header": "tr|A0A8V1AKT4-1|A0A8V1AKT4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AKT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT4/entry#A0A8V1AKT4-1", "sequence": { "sequence": "SSSSILLWNSRLFARSLLTCDSAMSARSSASSSSCWILRNLESPTHPGLQLLNLLLASLQGQLLCLIQAVLQVLHRLVQVLLHPLQVGTGVSLHLLLQPQGLIPAPDLSIQAALQGLHNSEVISLQLVNFLIFLCYLPVNLRLDLVELQLEAQDLPLFMLQGGLDK", "length": 166, "header": "tr|A0A8V1AKT4-1|A0A8V1AKT4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AKT4-1" }, "locus": { "chromosome": "18", "start_pos": 1266905, "end_pos": 1264687, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071444.1", "url": "https://www.ensembl.org/id/ENSGALT00010071444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044134.1", "url": "https://www.ensembl.org/id/ENSGALP00010044134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKT6-1", "uniprot_ac": "A0A8V1AKT6", "uniprot_id": "A0A8V1AKT6_CHICK", "mass": { "chemical_mass": 30385.0, "monoisotopic_mass": 30385.0 }, "refseq": { "ac": "XP_015135120", "name": "RING finger protein 208", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135120" }, "gene_names": [ { "name": "RNF208", "type": "recommended", "evidence": [ { "id": "A0A8V1AKT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6" } ] }, { "name": "RNF208", "type": "synonym", "evidence": [ { "id": "XP_015135120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135120" } ] } ], "protein_names": [ { "name": "RING finger protein 208", "type": "synonym", "evidence": [ { "id": "XP_015135120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135120" } ] }, { "name": "Ring finger protein 208", "type": "synonym", "evidence": [ { "id": "A0A8V1AKT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135120" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF208", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6", "locus": { "chromosome": "17", "start_pos": 1647726, "end_pos": 1653240, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028517", "url": "https://www.ensembl.org/id/ENSGALG00010028517" } ] } } ], "crossref": [ { "id": "cd16559", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16559", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417279", "url": "https://www.ncbi.nlm.nih.gov/gene/417279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417279", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVNQYVV", "url": "https://omabrowser.org/oma/group/IVNQYVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKT6", "url": "https://www.orthodb.org/?gene=A0A8V1AKT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015135120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPACCSLMQASFGDPRAVDSNVKTILMSCLKGQQVIIKMEAMKIIHPEKFSELQAAPPRYAPAPRREPPLVAKRAWPSESEIIVNQACGDIPALDATPAPLPLPRTPPLPRRERGYQGQRKGSSEVCFHRQPPSDEVIVNQYVLHPSTPCEPLECPTCGHMYNFTNKRPRILSCLHSVCEECLQILYESCPKYKFISCPTCKRETVLFTDYGLAALAVNTSILNRLPAEALAANPVQWSSDTDRSCYQTFRQYCGAACTCHIRNPLSSCTIM", "length": 273, "header": "tr|A0A8V1AKT6-1|A0A8V1AKT6_CHICK Isoform 1 of Ring finger protein 208 OS=Gallus gallus OX=9031 GN=RNF208 PE=4 SV=1 CANONICAL=A0A8V1AKT6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6/entry#A0A8V1AKT6-1", "sequence": { "sequence": "MLPACCSLMQASFGDPRAVDSNVKTILMSCLKGQQVIIKMEAMKIIHPEKFSELQAAPPRYAPAPRREPPLVAKRAWPSESEIIVNQACGDIPALDATPAPLPLPRTPPLPRRERGYQGQRKGSSEVCFHRQPPSDEVIVNQYVLHPSTPCEPLECPTCGHMYNFTNKRPRILSCLHSVCEECLQILYESCPKYKFISCPTCKRETVLFTDYGLAALAVNTSILNRLPAEALAANPVQWSSDTDRSCYQTFRQYCGAACTCHIRNPLSSCTIM", "length": 273, "header": "tr|A0A8V1AKT6-1|A0A8V1AKT6_CHICK Isoform 1 of Ring finger protein 208 OS=Gallus gallus OX=9031 GN=RNF208 PE=4 SV=1 CANONICAL=A0A8V1AKT6-1" }, "locus": { "chromosome": "17", "start_pos": 1651170, "end_pos": 1650352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069067.1", "url": "https://www.ensembl.org/id/ENSGALT00010069067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042509.1", "url": "https://www.ensembl.org/id/ENSGALP00010042509.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 98, "start_aa": "Thr", "end_pos": 98, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr98", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417279", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HFG4-1", "protein_name": "RING finger protein 208", "gene_name": "Rnf208", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPADPGPEVGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAATPCFPPAPRPTPTLAPKRAWPSDTEIIVNQACGGDMPTLEGAPHTPPLPRRPRKGSSELGFPRVAPVDEVIVNQYVIRPGPTASAPSSSGPVIAGEPLECPTCGHTYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCHRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGGESEGSCYQTFRQYCGAACTCHVRNPLSACSIM", "length": 265 }, "evidence": [ { "id": "A0A8V1AKT6", "url": "https://omabrowser.org/oma/group/A0A8V1AKT6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4ADR3-1", "protein_name": "RING finger protein 208", "gene_name": "Rnf208", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPADPGPEVGSGWPGLLMSCLKGPHVILKMEAMKIVHPEKFPELPAATPCFPPAPRPTPTLAPKRAWPSDTEIIVNQACGGDMPTLEGASHTPPLPRRPRKGSSELGFPRVAPVDEVIVNQYVIRPGPTASAPSSSGPVIAGEPLECPTCGHTYNVTQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCHRETVLFTDYGLAALAVNTSILSRLPPEALTAPSGGQWGGESEGSCYQTFRQYCGAACTCHVRNPLSACSIM", "length": 265 }, "evidence": [ { "id": "A0A8V1AKT6", "url": "https://omabrowser.org/oma/group/A0A8V1AKT6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MX21-1", "protein_name": "RING finger protein 208", "gene_name": "RNF208", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPADPGPEVGGGWPGFLMSCLKGPHVILKMEAMKMVHPEKFPELQAATPCFPPAPRPAPALAPKRAWPSDTEIIVNQACGGDMPALEGAPCTPPLPRRPRKGSAELGFPRVAPADEVIVNQYVIRPSPAAPGAPAAAVAAAAGEPLECPTCGHTYNATQRRPRVLSCLHSVCEQCLQILYESCPKYKFISCPTCRRETVLFTDYGLAALAINTSILSRLPPEALTAPSGGQWGGEPEGSCYQTFRQYCGAACTCHARNPLSACSIM", "length": 266 }, "evidence": [ { "id": "A0A8V1AKT6", "url": "https://omabrowser.org/oma/group/A0A8V1AKT6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K0W3-1", "protein_name": "RING finger protein 208", "gene_name": "Rnf208", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKT6" } ], "pmid": "" } ] }, { "name": "Biological Process", 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This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948290.3. 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506390" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BHLHA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2", "locus": { "chromosome": "19", "start_pos": 6792573, "end_pos": 6793553, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029789", "url": "https://www.ensembl.org/id/ENSGALG00010029789" } ] } } ], "crossref": [ { "id": "A0A8V1AKU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771883", "url": "https://www.ncbi.nlm.nih.gov/gene/771883", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKU2", "url": "https://www.orthodb.org/?gene=A0A8V1AKU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506390", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRAAAAQLGELDGSEEELERGAAPRACCRQEMWIPKGRDATACLGDTEEMKVRKRSRPARSKARRMAANVRERKRILDYNQAFNALRLVLKHDLGGKRLSKIATLRRAIHRIAALSLSLHCWPCTHSECRRQGVRDSRLVPPSAMGYGCYPSESQLHCYESLQEDRPAASPVFYPVGSQQKHTSNPQAIPLAPLPWQPGGLQSSGFQCLPIH", "length": 213, "header": "tr|A0A8V1AKU2-1|A0A8V1AKU2_CHICK Isoform 1 of Basic helix-loop-helix family member a9 OS=Gallus gallus OX=9031 GN=BHLHA9 PE=4 SV=1 CANONICAL=A0A8V1AKU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2/entry#A0A8V1AKU2-1", "sequence": { "sequence": "MSRAAAAQLGELDGSEEELERGAAPRACCRQEMWIPKGRDATACLGDTEEMKVRKRSRPARSKARRMAANVRERKRILDYNQAFNALRLVLKHDLGGKRLSKIATLRRAIHRIAALSLSLHCWPCTHSECRRQGVRDSRLVPPSAMGYGCYPSESQLHCYESLQEDRPAASPVFYPVGSQQKHTSNPQAIPLAPLPWQPGGLQSSGFQCLPIH", "length": 213, "header": "tr|A0A8V1AKU2-1|A0A8V1AKU2_CHICK Isoform 1 of Basic helix-loop-helix family member a9 OS=Gallus gallus OX=9031 GN=BHLHA9 PE=4 SV=1 CANONICAL=A0A8V1AKU2-1" }, "locus": { "chromosome": "19", "start_pos": 6793486, "end_pos": 6792848, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072063.1", "url": "https://www.ensembl.org/id/ENSGALT00010072063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044753.1", "url": "https://www.ensembl.org/id/ENSGALP00010044753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AKU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU2" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 116, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKV6-1", "uniprot_ac": "A0A8V1AKV6", "uniprot_id": "A0A8V1AKV6_CHICK", "mass": { "chemical_mass": 12372.0, "monoisotopic_mass": 12372.0 }, "refseq": {}, "gene_names": [ { "name": "LOC431317", "type": "recommended", "evidence": [ { "id": "A0A8V1AKV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V1AKV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC431317", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6", "locus": {} } ], "crossref": [ { "id": "A0A8V1AKV6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CPQESIT", "url": "https://omabrowser.org/oma/group/CPQESIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKV6", "url": "https://www.orthodb.org/?gene=A0A8V1AKV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AKV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCYDLCPPKTSMAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPACSPCPLPRYSRKLWDNCGPC", "length": 121, "header": "tr|A0A8V1AKV6-1|A0A8V1AKV6_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC431317 PE=3 SV=1 CANONICAL=A0A8V1AKV6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6/entry#A0A8V1AKV6-1", "sequence": { "sequence": "MSCYDLCPPKTSMAVPQPIAESCNELCARQCPDSTAFIQPPPVVVTFPGPILSSFPQQAVVGSSGAPAFGGSLGLGGLYGAGATQGSGGLCTFGRPYVSPACSPCPLPRYSRKLWDNCGPC", "length": 121, "header": "tr|A0A8V1AKV6-1|A0A8V1AKV6_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC431317 PE=3 SV=1 CANONICAL=A0A8V1AKV6-1" }, "locus": { "chromosome": "25", "start_pos": 1456003, "end_pos": 1455641, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069093.1", "url": "https://www.ensembl.org/id/ENSGALT00010069093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042535.1", "url": "https://www.ensembl.org/id/ENSGALP00010042535.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKV7-1", "uniprot_ac": "A0A8V1AKV7", "uniprot_id": "A0A8V1AKV7_CHICK", "mass": { "chemical_mass": 42031.0, "monoisotopic_mass": 42031.0 }, "refseq": { "ac": "XP_040506351", "name": "ribosomal protein S6 kinase-related protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506351" }, "gene_names": [ { "name": "SGK494", "type": "recommended", "evidence": [ { "id": "A0A8V1AKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV7" } ] }, { "name": "SGK494", "type": "synonym", "evidence": [ { "id": "XP_040506351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506351" } ] } ], "protein_names": [ { "name": "Ribosomal protein S6 kinase related", "type": "synonym", "evidence": [ { "id": "A0A8V1AKV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV7/entry#names_and_taxonomy" } ] }, { "name": "ribosomal protein S6 kinase-related protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040506351", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506351" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040506351.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506351", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506351" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGK494", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AKV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05123", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05123", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107054802", "url": "https://www.ncbi.nlm.nih.gov/gene/107054802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKV7", "url": "https://www.orthodb.org/?gene=A0A8V1AKV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24355", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24355", "database": "PANTHER", "categories": [ "Protein 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"MGAASSGSGPGPPQGRAVGSWVRALLRRSGSVQGPVPVPGLAVATEEPPFPGWPLPQLVSLFLPEFPVRPSARQQQLKILGLVAKGSFGTILKVLDCGREKVCAVKVVPKVEVLRRDTLKQCKEEVSIQRQVRHPFVHGLGDSWQGQRHLFIMCTYCSTGDLHALWRAAGRFTEATVRLFAAELVLVLVYLHDLGIVHRDVKMENILLDERGHLKLADFGLSRHLRCGERAHTICGTLQYMAPEVLSGGPYSHAADWWSLGVLLFALASGEFPVPPARDHVAMLERVKESSYASPPALSPALGRLLAELLCHNPLRRLRYLHHFQDHPFFRGLAFDAELLQKDPVAVAVAPRPTEQPLPDPTTFDDFDCDLTAAPPNRPWPG", "length": 382, "header": "tr|A0A8V1AKV7-1|A0A8V1AKV7_CHICK Isoform 1 of Ribosomal protein S6 kinase related OS=Gallus gallus OX=9031 GN=SGK494 PE=4 SV=1 CANONICAL=A0A8V1AKV7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV7/entry#A0A8V1AKV7-1", "sequence": { "sequence": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKX6-1", "uniprot_ac": "A0A8V1AKX6", "uniprot_id": "A0A8V1AKX6_CHICK", 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"https://www.uniprot.org/uniprotkb/A0A8V1AQ87#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX6", "locus": { "chromosome": "18", "start_pos": 2722480, "end_pos": 2798484, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029921", "url": "https://www.ensembl.org/id/ENSGALG00010029921" } ] } } ], "crossref": [ { "id": "A0A8V1AKX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417321", "url": "https://www.ncbi.nlm.nih.gov/gene/417321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKX6", "url": "https://www.orthodb.org/?gene=A0A8V1AKX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ87", "url": "https://www.orthodb.org/?gene=A0A8V1AQ87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19957:SF124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957:SF124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AKX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPDPWLSQYDAACQLAQEVAERIQERSRHRRNGESSAKLNVIIRSSLQNLKEKIDQLKDSLLRAVSTHQITQLEGDRRQNLVDDLLTRQKQLQSSYKNEGTEPDVISSELPKIHRPPPRAMKASSLMAGGVKRGVTNPWLLEESEETRGLGFDDIRQQQRRIIEEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLTNLVENTDSKLRTQTRHVKMVDRKSTSCGMLVVIVLLLIAIAVVAVWPTK", "length": 252, "header": "tr|A0A8V1AKX6-1|A0A8V1AKX6_CHICK Isoform 1 of Syntaxin-8 OS=Gallus gallus OX=9031 GN=STX8 PE=1 SV=1 CANONICAL=A0A8V1AKX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX6/entry#A0A8V1AKX6-1", "sequence": { "sequence": "MAPDPWLSQYDAACQLAQEVAERIQERSRHRRNGESSAKLNVIIRSSLQNLKEKIDQLKDSLLRAVSTHQITQLEGDRRQNLVDDLLTRQKQLQSSYKNEGTEPDVISSELPKIHRPPPRAMKASSLMAGGVKRGVTNPWLLEESEETRGLGFDDIRQQQRRIIEEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLTNLVENTDSKLRTQTRHVKMVDRKSTSCGMLVVIVLLLIAIAVVAVWPTK", "length": 252, "header": "tr|A0A8V1AKX6-1|A0A8V1AKX6_CHICK Isoform 1 of Syntaxin-8 OS=Gallus gallus OX=9031 GN=STX8 PE=1 SV=1 CANONICAL=A0A8V1AKX6-1" }, "locus": { "chromosome": "18", "start_pos": 2798430, "end_pos": 2723057, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072316.1", "url": "https://www.ensembl.org/id/ENSGALT00010072316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044785.1", "url": "https://www.ensembl.org/id/ENSGALP00010044785.1" } ] } }, { "isoform_ac": "A0A8V1AQ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX6/entry#A0A8V1AQ87-1", "sequence": { "sequence": "MAPDPWLSQYDAACQLAQEVAERIQERSRHRRNGESSAKLNVIIRSSLQNLKEKIDQLKDSLLRAVSTHQITQLEGDRRQNLVDDLLTRQKQLQSSYKNEGTEPDVIRSSLMAGGVKRGVTNPWLLEESEETRGLGFDDIRQQQRRIIEEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLTNLVENTDSKLRTQTRHVKMVDRKSTSCAQRPGRATASCILCHSLKHLA", "length": 235, "header": "tr|A0A8V1AQ87-1|A0A8V1AQ87_CHICK Computationally mapped isoform of Syntaxin-8 OS=Gallus gallus OX=9031 GN=STX8 PE=1 SV=1 CANONICAL=A0A8V1AKX6-1" }, "locus": { "chromosome": "18", "start_pos": 2798430, "end_pos": 2744486, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072315.1", "url": "https://www.ensembl.org/id/ENSGALT00010072315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044784.1", "url": "https://www.ensembl.org/id/ENSGALP00010044784.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chloride channel inhibitor activity", "id": "GO:0019869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKX6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKX6", "url": 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"expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GGNBP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7", "locus": { "chromosome": "19", "start_pos": 8650168, "end_pos": 8627096, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029925", "url": "https://www.ensembl.org/id/ENSGALG00010029925" } ] } } ], "crossref": [ { "id": "A0A8V1AKY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "425053", "url": "https://www.ncbi.nlm.nih.gov/gene/425053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MMLMDLN", "url": "https://omabrowser.org/oma/group/MMLMDLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFJ3", "url": "https://www.orthodb.org/?gene=A0A8V1AFJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKY7", "url": "https://www.orthodb.org/?gene=A0A8V1AKY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AME5", "url": "https://www.orthodb.org/?gene=A0A8V1AME5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANX9", "url": "https://www.orthodb.org/?gene=A0A8V1ANX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ90", "url": "https://www.orthodb.org/?gene=A0A8V1AQ90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13601:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13601:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPGPKSPSIKRGALRTRRAAGVRTQSPTAAGRGAAPRQHPLLGQCAARCVHPPQSKRCSLESRKRSSPARIRNHPQVLLLRREEGAQRLQRGDAAEMARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGYERRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 797, "header": "tr|A0A8V1AKY7-1|A0A8V1AKY7_CHICK Isoform 1 of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=4 SV=1 CANONICAL=A0A8V1AKY7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7/entry#A0A8V1AFJ3-1", "sequence": { "sequence": "MARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGEGSSSTHSAEKLSADKKSSEDSKKEESKCRITFHYGPFQGAVRGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGYERRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 743, "header": "tr|A0A8V1AFJ3-1|A0A8V1AFJ3_CHICK Computationally mapped isoform of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=4 SV=1 CANONICAL=A0A8V1AKY7-1" }, "locus": { "chromosome": "19", "start_pos": 8649715, "end_pos": 8634121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072321.1", "url": "https://www.ensembl.org/id/ENSGALT00010072321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044788.1", "url": "https://www.ensembl.org/id/ENSGALP00010044788.1" } ] } }, { "isoform_ac": "A0A8V1AKY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7/entry#A0A8V1AKY7-1", "sequence": { "sequence": "MQPGPKSPSIKRGALRTRRAAGVRTQSPTAAGRGAAPRQHPLLGQCAARCVHPPQSKRCSLESRKRSSPARIRNHPQVLLLRREEGAQRLQRGDAAEMARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGYERRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 797, "header": "tr|A0A8V1AKY7-1|A0A8V1AKY7_CHICK Isoform 1 of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=4 SV=1 CANONICAL=A0A8V1AKY7-1" }, "locus": { "chromosome": "19", "start_pos": 8649715, "end_pos": 8627295, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072323.1", "url": "https://www.ensembl.org/id/ENSGALT00010072323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044790.1", "url": "https://www.ensembl.org/id/ENSGALP00010044790.1" } ] } }, { "isoform_ac": "A0A8V1AME5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7/entry#A0A8V1AME5-1", "sequence": { "sequence": "MARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLVSNHLHCNYGLLHTASNRCD", "length": 651, "header": "tr|A0A8V1AME5-1|A0A8V1AME5_CHICK Computationally mapped isoform of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=4 SV=1 CANONICAL=A0A8V1AKY7-1" }, "locus": { "chromosome": "19", "start_pos": 8648860, "end_pos": 8634121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072320.1", "url": "https://www.ensembl.org/id/ENSGALT00010072320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044787.1", "url": "https://www.ensembl.org/id/ENSGALP00010044787.1" } ] } }, { "isoform_ac": "A0A8V1ANX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7/entry#A0A8V1ANX9-1", "sequence": { "sequence": "MARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGYERRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 662, "header": "tr|A0A8V1ANX9-1|A0A8V1ANX9_CHICK Computationally mapped isoform of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=4 SV=1 CANONICAL=A0A8V1AKY7-1" }, "locus": { "chromosome": "19", "start_pos": 8649715, "end_pos": 8634121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072319.1", "url": "https://www.ensembl.org/id/ENSGALT00010072319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044786.1", "url": "https://www.ensembl.org/id/ENSGALP00010044786.1" } ] } }, { "isoform_ac": "A0A8V1AQ90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7/entry#A0A8V1AQ90-1", "sequence": { "sequence": "MVFSSTLRLQRGDAAEMARLVAVCRDGEEEFPFEKRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLNIAMMVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLAVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGYERRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMAVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCEIPTPLQAAEEKEINQAKENLDFTENSCKACGSTEEANNCVEVIVTNESTSCTCPSSGTLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDENGDDSCVHRCDDKEEDGDSCVECWANSEESNTKGKNKKKKKKSKTLKCENEHIQKLGSCMADPGNRETSGNTTHTEFHRDKTKDTHAESCCSSEKSGQQLPWFEHMKNVSQFAEPTEMSLVPDTGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNKSFYSNREQYRQHLKEKFNKYCRLNDHKRPICNGWLTTAGAN", "length": 716, "header": "tr|A0A8V1AQ90-1|A0A8V1AQ90_CHICK Computationally mapped isoform of Gametogenetin-binding protein 2 OS=Gallus gallus OX=9031 GN=GGNBP2 PE=4 SV=1 CANONICAL=A0A8V1AKY7-1" }, "locus": { "chromosome": "19", "start_pos": 8649715, "end_pos": 8630809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072322.1", "url": "https://www.ensembl.org/id/ENSGALT00010072322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044789.1", "url": "https://www.ensembl.org/id/ENSGALP00010044789.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M6R7-1", "protein_name": "Gametogenetin-binding protein 2", "gene_name": "GGNBP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGTQLKQFIQRHSMLKQQDLSIAMVVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGYERRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCDIPTPLQTADEKEVSQEKETDFIENSCKACGSTEDGNSCVEVIVTNENTSCTCPTSGNLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDEHGDDSCVHHCEDKEDDGDSCVECWANSEENSTKGKNKKKKKKSKMLKCDEHIQKLGSCITDPGTRETSGNTVHTVFHRDKTKDAHPESCCSSEKGGQPLAWFEHRKNVPQCAEPTETSFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYSNREQYRQHLKEKFNKYCRLNDHKRPICSGWLTTAGAN", "length": 698 }, "evidence": [ { "id": "A0A8V1AKY7", "url": "https://omabrowser.org/oma/group/A0A8V1AKY7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5SV77-1", "protein_name": "Gametogenetin-binding protein 2", "gene_name": "Ggnbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLSIAMVVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSLTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCDTPASLHTADEKAVSREKETDFIENSCNACGSAEDGETCVEVMVTSENTSCTCPSSGNLLGSPKIKKGMSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDEHGEDSCVHHCEDKEDDGDSCVECWANSEENNIKGKNKKKKKKSKMLKCDEHIQKLGSCITDPGNRETSGNTMHTVFHRDKTKDAHPESCCSTEKGGQPLPWFEHRKSVPQFTEPTEMSFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYSNREQYRQHLKEKFNKYCRLNDHKRPVCSGWLTTAGAN", "length": 696 }, "evidence": [ { "id": "A0A8V1AKY7", "url": "https://omabrowser.org/oma/group/A0A8V1AKY7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6GVH5-1", "protein_name": "Gametogenetin-binding protein 2", "gene_name": "Ggnbp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHSMLKQQDLSIAMVVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSLTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCDSPASLHTADEKAVSQEKETDFMENSCKACGSTEDGNTCVEVIVTNENTSCTCPSSGNLLGSPKIKKGMSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDEHGEDPCVHHCEDKEDDGDSCVECWANSEENNTKGKNKKKKKKSKMLKCDEHIQKLGSCITDPGNRETSGNTMHTVFHRDKTKDAHPESCCSTEKGGQPLPWFEHRKNVPQFTEPTEMSFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYSNREQYRQHLKEKFNKYCRLNDHKRPVCSGWLTTAGAN", "length": 696 }, "evidence": [ { "id": "A0A8V1AKY7", "url": "https://omabrowser.org/oma/group/A0A8V1AKY7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H3C7-1", "protein_name": "Gametogenetin-binding protein 2", "gene_name": "GGNBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRHGMLKQQDLSIAMVVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKGVLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWMDVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEKGYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLTCLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFSEEERVRELKQEKKRQKRKNRRKNKCVCDIPTPLQTADEKEVSQEKETDFIENSSCKACGSTEDGNTCVEVIVTNENTSCTCPSSGNLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSREGSDVACTEGICNHDEHGDDSCVHHCEDKEDDGDSCVECWANSEENDTKGKNKKKKKKSKILKCDEHIQKLGSCITDPGNRETSGNTMHTVFHRDKTKDTHPESCCSSEKGGQPLPWFEHRKNVPQFAEPTETLFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYSNREQYRQHLKEKFNKYCRLNDHKRPICSGWLTTAGAN", "length": 697 }, "evidence": [ { "id": "A0A8V1AKY7", "url": "https://omabrowser.org/oma/group/A0A8V1AKY7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 755, "end_pos": 757, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 533, "end_pos": 535 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 755, "end_pos": 757 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AKZ7-1", "uniprot_ac": "A0A8V1AKZ7", "uniprot_id": "A0A8V1AKZ7_CHICK", "mass": { "chemical_mass": 79903.0, "monoisotopic_mass": 79903.0 }, "refseq": { "ac": "XP_415871", "name": "protein phosphatase 1E isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415871" }, "gene_names": [ { "name": "PPM1E", "type": "recommended", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "name": "PPM1E", "type": "synonym", "evidence": [ { "id": "XP_415871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415871" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1E", "type": "recommended", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7/entry#names_and_taxonomy" } ] }, { "name": "Ca(2+)/calmodulin-dependent protein kinase phosphatase N", "type": "synonym", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7/entry#names_and_taxonomy" } ] }, { "name": "CaMKP-nucleus", "type": "synonym", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7/entry#names_and_taxonomy" } ] }, { "name": "Partner of PIX 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7/entry#names_and_taxonomy" } ] }, { "name": "Partner of PIX-alpha", "type": "synonym", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1E isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415871" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415871.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415871" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPM1E", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7", "locus": { "chromosome": "19", "start_pos": 7645892, "end_pos": 7590830, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029230", "url": "https://www.ensembl.org/id/ENSGALG00010029230" } ] } } ], "crossref": [ { "id": "A0A8V1AKZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AKZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417627", "url": "https://www.ncbi.nlm.nih.gov/gene/417627", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417627", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417627", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHLRYHY", "url": "https://omabrowser.org/oma/group/SHLRYHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKZ7", "url": "https://www.orthodb.org/?gene=A0A8V1AKZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF535", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF535", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGSGSSGGGGSAEEKNYRRFLELFLGEFRGPFGAEPAPAPPPPAADTVDTAASEEDPAAEGEAAAAEAEEGDSADPRPPTPPPPPPPLPPLPRPLSEYITEEEVEGECLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYLPKHVDNADGIIQIETVKLARLVFSKLHEICSNWVKEFPLQPKPHRYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNMVHQEMFQHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWLGDSQVMLVRKGQAVELMKPHKPDREDEKKRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGSEDYLILACDGFYDTVNPDEAVKVVADHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNAAVSVSEESDWTENSFQGGQEDNGEDKENHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSIGSGINPFDDQGYVDLTKTETSMPNSAKYLPPIQVFSPGIPKNASLINGLTVKNESPESTSSICGQSNPREYSAPVSLHAAGQSIYRVKGLTPISFGLEDELFKSLGKQVAFFHFRFCNGKRRRGARLKPKFHTPLLAREPSHREGSGLPLPVRSRGSTRLLVRHSPWWRLPRPNAYSESMFLMRRQSHCIPDAYLHQCCEM", "length": 725, "header": "tr|A0A8V1AKZ7-1|A0A8V1AKZ7_CHICK Isoform 1 of Protein phosphatase 1E OS=Gallus gallus OX=9031 GN=PPM1E PE=1 SV=1 CANONICAL=A0A8V1AKZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7/entry#A0A8V1AKZ7-1", "sequence": { "sequence": "MAAGGSGSSGGGGSAEEKNYRRFLELFLGEFRGPFGAEPAPAPPPPAADTVDTAASEEDPAAEGEAAAAEAEEGDSADPRPPTPPPPPPPLPPLPRPLSEYITEEEVEGECLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYLPKHVDNADGIIQIETVKLARLVFSKLHEICSNWVKEFPLQPKPHRYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNMVHQEMFQHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWLGDSQVMLVRKGQAVELMKPHKPDREDEKKRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGSEDYLILACDGFYDTVNPDEAVKVVADHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNAAVSVSEESDWTENSFQGGQEDNGEDKENHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSIGSGINPFDDQGYVDLTKTETSMPNSAKYLPPIQVFSPGIPKNASLINGLTVKNESPESTSSICGQSNPREYSAPVSLHAAGQSIYRVKGLTPISFGLEDELFKSLGKQVAFFHFRFCNGKRRRGARLKPKFHTPLLAREPSHREGSGLPLPVRSRGSTRLLVRHSPWWRLPRPNAYSESMFLMRRQSHCIPDAYLHQCCEM", "length": 725, "header": "tr|A0A8V1AKZ7-1|A0A8V1AKZ7_CHICK Isoform 1 of Protein phosphatase 1E OS=Gallus gallus OX=9031 GN=PPM1E PE=1 SV=1 CANONICAL=A0A8V1AKZ7-1" }, "locus": { "chromosome": "19", "start_pos": 7645820, "end_pos": 7590949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070645.1", "url": "https://www.ensembl.org/id/ENSGALT00010070645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043336.1", "url": "https://www.ensembl.org/id/ENSGALP00010043336.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 83, "start_aa": "Thr", "end_pos": 83, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr83", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417627", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417627", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N580-1", "protein_name": "Protein phosphatase 1E", "gene_name": "PPM1E", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGCSPEEKTYRRFLELFLGEFRGPCGGGEPQPEPEPEESEPEPEPELVAAEAREASVEEAGEAAAAGAASEEGEHEQEREDPEPEEEAVEEEAAAAAAAAGEEAAARGQSAVPPPQPRLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLVRQETFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEDSDWTENSFQGGQEAGGDDKESHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSPGSQGNVLEDPGYLDLTQIETSKPHGAQFLPPVEMFGPGAPKRANLINELIMEKKSVPSSLPEWSGAGEVLSSFNVGSTGQQVCSMGSLPPVCSRLENEQFKFLGKRVSRLSHLHYHYSKRRHGFRFNPKFYSFLSAQEPSHKTGSSLSSLIRNGKRNSMLRSSLPWRQNSWKGYSENVMRKPKKSNDPAHPELPWSFKI", "length": 755 }, "evidence": [ { "id": "A0A8V1AKZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AKZ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LNY3-1", "protein_name": "Protein phosphatase 1E", "gene_name": "PPM1E", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGCSPEEKTYRRFLELFLGEFRGPCGGGEPEPEPEPESEPESELVAAEATEASVEESGEGAATVAATEEGEQEQEQDPEPEEAVEEEALAAAEGEEEAAAARGQSAVPPPPQPLLPPLPPLPRPLSERITLEEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYIPKEMDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLHRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVLEDPGYLDLTQIEASKPHSAQFLPPVEMFGPGAPKKANLINELIMEKKSVQSSLPERSGAGEFLSSFNLGSTGQQICRMESLSPVCSRLENEQFRFLGKRVSRLSHLRYHYSKRRHGFRFNPKFHSFLSAREPSHKAGTSLSSLIRSGKRNRMLRSSLPWRQSSWKGYNENMMRKLKKNDIPYPDLPWSFKI", "length": 750 }, "evidence": [ { "id": "A0A8V1AKZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AKZ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80TL0-1", "protein_name": "Protein phosphatase 1E", "gene_name": "Ppm1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPESEPEPEPEAELVAAEAAEASGEEPGEDAATVEATEEGEQDQDPEPEDEAVEEETATEGEEEEEEEAAAPGHSAVPPPPQPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHCIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQIYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESEWTENSFQGGQEDGGDDKETHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSPGPQINVLEDPDYLDLTQIEASKPHSTQFLPPVEMIGPGAPKKDLNELIMEERSVKSSLPERSGAGEPRVSFNLGSTGQQICRMENLSPVSSGLENEQFKSRGKTASRLYHLRHHYSKRQRGFRFNPKFYSFLSAREPSHKIGISLSSLTRSGKRNKMLRSSLPWRENSWEGYSGNVKIRKRNDIPCPDFPWSYKI", "length": 749 }, "evidence": [ { "id": "A0A8V1AKZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AKZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80Z30-1", "protein_name": "Protein phosphatase 1E", "gene_name": "Ppm1e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPESEPEPEPEAELVAAEAAEASGEDPGEDAATVEAAEEGVQDQDPEPEEEAVEEEAAAEGEEEEEEEEAAAPGHSAVPPPQPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHCIPKETDGTEGTVEIETVKLARSVFSKLHEICCNWVKDFPLRRRPQIYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYEGRVDSFTDRTSLSPGPQINVLEDPDYLDLTQIETSKPHSTQFLPPVEMIGPGAPKKAYVNELIMEESSVTPSQPERSGAGELLVSFNLGSTGQQICRMENLSPVYSGLENEQFKSPGKRASRLYHLRHHYSKRQRGFRFNPKFYSFFSAQESSRKIGISLSSLTRSGKRNKMLRSSLPWRENSWEGYSGNMAIRKRNNISCPDLPWDYKI", "length": 750 }, "evidence": [ { "id": "A0A8V1AKZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AKZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WY54-2", "protein_name": "Protein phosphatase 1E", "gene_name": "PPM1E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPEPEPEPEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPEEEAAVEGEEEEEGAATAAAAPGHSAVPPPPPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCPSFLAAALARATSDEVLQSDLSAHYIPKETDGTEGTVEIETVKLARSVFSKLHEICCSWVKDFPLRRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTENSFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVLEDPGYLDLTQIEASKPHSAQFLLPVEMFGPGAPKKANLINELMMEKKSVQSSLPEWSGAGEFPTAFNLGSTGEQIYRMQSLSPVCSGLENEQFKSPGNRVSRLSHLRHHYSKKWHRFRFNPKFYSFLSAQEPSHKIGTSLSSLTGSGKRNRIRSSLPWRQNSWKGYSENMRKLRKTHDIPCPDLPWSYKIE", "length": 755 }, "evidence": [ { "id": "A0A8V1AKZ7", "url": "https://omabrowser.org/oma/group/A0A8V1AKZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" }, { "name": "cellular response to xenobiotic stimulus", "id": "GO:0071466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071466", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AKZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A6D3", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL07-1", "uniprot_ac": "A0A8V1AL07", "uniprot_id": "A0A8V1AL07_CHICK", "mass": { "chemical_mass": 28300.0, "monoisotopic_mass": 28300.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL07/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL07", "locus": {} } ], "crossref": [ { "id": "A0A8V1AL07", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL07", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR043247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR47115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47115:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47115:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QIEHESFVTAEVEKAKAAVQCSRVWDITSRLLAQQKSTAELEQHIRACKEKRRALKDTLQELELKHAELKFHQPPSAISCRKLEAELRVRLQQEEARLEQARAQYVSNQELLLQFENGIDNLVIRLHGINVPEQDVSVEFKGVDEKLQYCRQKLQHLAQRVASLPAHTYSPDEDNETFVKVRNLMEKTTAREPWNLKIPLEDIGSGVQAPSDFVEEDHDLVLTREDIKKQGLHLIESKIRSSKRK", "length": 245, "header": "tr|A0A8V1AL07-1|A0A8V1AL07_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AL07-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL07/entry#A0A8V1AL07-1", "sequence": { "sequence": "QIEHESFVTAEVEKAKAAVQCSRVWDITSRLLAQQKSTAELEQHIRACKEKRRALKDTLQELELKHAELKFHQPPSAISCRKLEAELRVRLQQEEARLEQARAQYVSNQELLLQFENGIDNLVIRLHGINVPEQDVSVEFKGVDEKLQYCRQKLQHLAQRVASLPAHTYSPDEDNETFVKVRNLMEKTTAREPWNLKIPLEDIGSGVQAPSDFVEEDHDLVLTREDIKKQGLHLIESKIRSSKRK", "length": 245, "header": "tr|A0A8V1AL07-1|A0A8V1AL07_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AL07-1" }, "locus": { "chromosome": "19", "start_pos": 1328575, "end_pos": 1326176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071524.1", "url": "https://www.ensembl.org/id/ENSGALT00010071524.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044214.1", "url": "https://www.ensembl.org/id/ENSGALP00010044214.1" } ] } }, { "isoform_ac": "A0A8V1AMU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL07/entry#A0A8V1AMU4-1", "sequence": { "sequence": "MSLQQARYDLAVDFPSLLMQDSALGSQVQATRSQIEHESFVTAEVEKAKAAVQCSRVWDITSRLLAQQKSTAELEQHIRACKEKRRALKDTLQELELKHAELKFHQPPSAIRMSPLSSKGWMRSCSTAGRSCSTWPSAWPPCLLTPTAPTRTTRLL", "length": 156, "header": "tr|A0A8V1AMU4-1|A0A8V1AMU4_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AL07-1" }, "locus": { "chromosome": "19", "start_pos": 1328762, "end_pos": 1327012, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071523.1", "url": "https://www.ensembl.org/id/ENSGALT00010071523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044213.1", "url": "https://www.ensembl.org/id/ENSGALP00010044213.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL15-1", "uniprot_ac": "A0A8V1AL15", "uniprot_id": "A0A8V1AL15_CHICK", "mass": { "chemical_mass": 27310.0, "monoisotopic_mass": 27310.0 }, "refseq": { "ac": "XP_001233973", "name": "cytochrome c oxidase assembly protein COX11, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233973" }, "gene_names": [ { "name": "COX11", "type": "recommended", "evidence": [ { "id": "A0A8V1AL15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15" } ] }, { "name": "COX11", "type": "synonym", "evidence": [ { "id": "XP_001233973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233973" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V1AL15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase assembly protein COX11, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_001233973", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233973" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233973.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233973" } ] }, { "annotation": "Assembly factor for cytochrome c oxidase (respiratory chain complex IV, CIV). Probably acts as a metallochaperone that delivers copper to the copper B site of COX1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15#function" }, { "database": "UniProtKB", "id": "ARBA00094317", "url": "https://www.uniprot.org/uniprotkb/ARBA00094317#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COX11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15", "locus": { "chromosome": "18", "start_pos": 6467557, "end_pos": 6470361, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029237", "url": "https://www.ensembl.org/id/ENSGALG00010029237" } ] } } ], "crossref": [ { "id": "A0A8V1AL15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL15", "database": "AlphaFoldDB", "categories": [] }, { "id": "770638", "url": "https://www.ncbi.nlm.nih.gov/gene/770638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770638", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKLECFC", "url": "https://omabrowser.org/oma/group/NKLECFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL15", "url": "https://www.orthodb.org/?gene=A0A8V1AL15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21320:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21320:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04442", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04442", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233973", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233973", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPGPRLQLCAGALRALALGRAVSRPCRGGWTSPRLQARGLRSSNPFTRRQEEEWRRRNRTALTYIAAAAVGMVGMSYAAVPLYRLYCQATGLGGTTGAGRGAERLEEMRPVRERVLKVTFNADVHAGLQWNFRPQQSEIYVVPGETALAFYKAKNPTDKPIIGISTYNVVPFEAGQYFNKIQCFCFEEQWLNPQEEVDMPVFFYIDPEFAEDPKMAKVDSITLSYTFFEAKEGQHLPLPGYQ", "length": 243, "header": "tr|A0A8V1AL15-1|A0A8V1AL15_CHICK Isoform 1 of Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Gallus gallus OX=9031 GN=COX11 PE=3 SV=1 CANONICAL=A0A8V1AL15-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AL15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL15/entry#A0A8V1AL15-1", "sequence": { "sequence": "MGPGPRLQLCAGALRALALGRAVSRPCRGGWTSPRLQARGLRSSNPFTRRQEEEWRRRNRTALTYIAAAAVGMVGMSYAAVPLYRLYCQATGLGGTTGAGRGAERLEEMRPVRERVLKVTFNADVHAGLQWNFRPQQSEIYVVPGETALAFYKAKNPTDKPIIGISTYNVVPFEAGQYFNKIQCFCFEEQWLNPQEEVDMPVFFYIDPEFAEDPKMAKVDSITLSYTFFEAKEGQHLPLPGYQ", "length": 243, "header": "tr|A0A8V1AL15-1|A0A8V1AL15_CHICK Isoform 1 of Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Gallus gallus OX=9031 GN=COX11 PE=3 SV=1 CANONICAL=A0A8V1AL15-1" }, "locus": { "chromosome": "18", "start_pos": 6470324, "end_pos": 6468967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070665.1", "url": "https://www.ensembl.org/id/ENSGALT00010070665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043356.1", "url": "https://www.ensembl.org/id/ENSGALP00010043356.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770638", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KMZ6-1", "protein_name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "gene_name": "COX11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGLWRPAWRRVVFCGWSWSHLGRPTRAAERAEPCLRPGRSGPAGTEQGLRRLGTWRRPSPAEQPARRPKSTNPYTRSQEEDWRRRNKTVLTYMAAAAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDQIENMVPVKDRIIKITFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGHTLPVPGYNSNQQLSPASNL", "length": 282 }, "evidence": [ { "id": "A0A8V1AL15", "url": "https://omabrowser.org/oma/group/A0A8V1AL15/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZNJ0-1", "protein_name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "gene_name": "Cox11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGLWCPGWRFITLCGRGWSQPRWSGRTVVNAERALRPGWNGVGGAEQGLRRLGTWKRPSGARGPVAQPPRRPKSSNPFQRAQEDEWRRRNKTVLTYVAAAAVGMLGASYAAVPLYRLYCQVGRDEARHGSHLSHHSVPEAEVTHPWSPRFQTGKDVPKTTGLGGSAVAGHASDQIENMVPVKDRIIKVTFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGHKLAVPGYN", "length": 313 }, "evidence": [ { "id": "A0A8V1AL15", "url": "https://omabrowser.org/oma/group/A0A8V1AL15/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RSF6-1", "protein_name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "gene_name": "COX11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGLWRLGWSRVAFCGWPWSHLGAPTRAAERIEPYLGHGRSGTGGAERGLRRLGTWRRPSLAVQPLRRPKSTNPFTREQEEDWRRRNKTVLTYVAAAAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDQIENMVPVKDRIIKVTFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGQKLPVPGYN", "length": 271 }, "evidence": [ { "id": "A0A8V1AL15", "url": "https://omabrowser.org/oma/group/A0A8V1AL15/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6P8I6-1", "protein_name": "Cytochrome c oxidase assembly protein COX11, mitochondrial", "gene_name": "Cox11", "tax_id": 10090, 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Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. May play a role during development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9#function" }, { "database": "UniProtKB", "id": "ARBA00045929", "url": "https://www.uniprot.org/uniprotkb/ARBA00045929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9", "locus": { "chromosome": "28", "start_pos": 3318729, "end_pos": 3307148, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027533", "url": "https://www.ensembl.org/id/ENSGALG00010027533" } ] } } ], "crossref": [ { "id": "A0A8V1AGV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AGV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9G8", "url": "https://www.orthodb.org/?gene=A0A8V1A9G8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9H3", "url": "https://www.orthodb.org/?gene=A0A8V1A9H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC74", "url": "https://www.orthodb.org/?gene=A0A8V1AC74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEV2", "url": "https://www.orthodb.org/?gene=A0A8V1AEV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGV9", "url": "https://www.orthodb.org/?gene=A0A8V1AGV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18763:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18763:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9G8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC74", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPMEVALVSDAAGPLCNCSVWELHSGSALPGYRGGNTGPRGLALLGGEHLLGAQLGKSYINVWELQRKDQLQQKIICPGPVTCLTASPNGLYILAGVAESIYLWEVSNGNLLAILNRHYQDLTCLCFTDDSSHFLSGAKDCLALVWNLYSVLQAEPSQIPDPRHVWSRHSLPITDMCCGFGGPLARAATASLDQTAKLWEVSSGELLLSVLFDVGIMAVTLDLSEYHMFCGGMDGSIFQVDLFQRDRTFQTERENGKIFKGHRNQVTCLSVSTDGSLLLSGSHDETVRLWDIQSKQCLKTMNHKGPVTNAFIVLAPANMLNPDGKPSVPLPKFSKHLYGTESTDEQGSEGVTLRLGLHQQESGESYLEKAEKMYSQMCSTREKNLMGDQEHLTIQVSELEEEVSTLRKINKNLFDFSARIITKPAK", "length": 428, "header": "tr|A0A8V1AGV9-1|A0A8V1AGV9_CHICK Isoform 1 of WD repeat-containing protein 18 OS=Gallus gallus OX=9031 GN=WDR18 PE=1 SV=1 CANONICAL=A0A8V1AGV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9/entry#A0A8V1A9G8-1", "sequence": { "sequence": "MAAPMEVALVSDAAGPLCNCSVWELHSGSALPGYRGGNTGPRGLALLGGEHLLGAQLGKSYINVWELQRKDQLQQKIICPGPVTCLTASPNGLYILAGVAESIYLWEVSNGNLLAILNRHYQDLTCLCFTDDSSHFLSGAKDCLALVWNLYSVLQAEPSQIPDPRHVWSRHSLPITDMCCGFGGPLARAATASLDQTAKLWEVSSGELLLSVLFDVGIMAVTLDLSEYHMFCGGMDGSIFQVDLCAWPVQRDRTFQTERENGKIFKGHRNQVTCLSVSTDGSLLLSGSHDETVRLWDIQSKQCLKTMNHKGPVTNAFIVLAPANMLNPDGKPSVPLPKFSKHLYGTESTDEQGSEGVTLRLGLHHPGWCSHLSSPPGAVVWALSAVRRC", "length": 389, "header": "tr|A0A8V1A9G8-1|A0A8V1A9G8_CHICK Computationally mapped isoform of WD repeat-containing protein 18 OS=Gallus gallus OX=9031 GN=WDR18 PE=1 SV=1 CANONICAL=A0A8V1AGV9-1" }, "locus": { "chromosome": "28", "start_pos": 3316724, "end_pos": 3307230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066687.1", "url": "https://www.ensembl.org/id/ENSGALT00010066687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040828.1", "url": "https://www.ensembl.org/id/ENSGALP00010040828.1" } ] } }, { "isoform_ac": "A0A8V1A9H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9/entry#A0A8V1A9H3-1", "sequence": { "sequence": "MAAPMEVALVSDAAGPLCNCSVWELHSGSALPGYRGGNTGPRGLALLGGEHLLGAQLGKSYINVWELQRKDQLQQKIICPGPVTCLTASPNGLYILAGVAESIYLWEVSNGNLLAILNRHYQDLTCLCFTDDSSHFLSGAKDCLALVWNLYSVLQAEPSQIPDPRHVWSRHSLPITDMCCGFGGPLARAATASLDQTAKLWEVSSGELLLSVLFDVGIMAVTLDLSEYHMFCGGMDGSIFQVDLCAWPVQRDRTFQTERENGKIFKGHRNQVTCLSVSTDGSLLLSGSHDETVRLWDIQSKQCLKTMNHKGRHALISVILPSLSVKSCCCLALTLPSAIQAFLCCLFHPFGKGRGIKGMPSLSGVGF", "length": 367, "header": "tr|A0A8V1A9H3-1|A0A8V1A9H3_CHICK Computationally mapped isoform of WD repeat domain 18 OS=Gallus gallus OX=9031 GN=WDR18 PE=1 SV=1 CANONICAL=A0A8V1AGV9-1" }, "locus": { "chromosome": "28", "start_pos": 3312984, "end_pos": 3307230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066693.1", "url": "https://www.ensembl.org/id/ENSGALT00010066693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040834.1", "url": "https://www.ensembl.org/id/ENSGALP00010040834.1" } ] } }, { "isoform_ac": "A0A8V1AC74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9/entry#A0A8V1AC74-1", "sequence": { "sequence": "MAAPMEVALVSDAAGPLCNCSVWELHSGSALPGYRGGNTGPRGLALLGGEHLLGAQLGKSYINVWELQRKDQLQQKIICPGPVTCLTASPNGLYILAGVAESIYLWEVSNGNLLAILNRHYQDLTCLCFTDDSSHFLSGAKDCLALVWNLYSVLQAEPSQIPDPRHVWSRHSLPITDMCCGFGGPLARAATASLDQTAKLWEVSSGELLLSVLFDVGIMAVTLDLSEYHMFCGGMDGSIFQVDLCAWPVQRDRTFQTERENGKIFKGHRNQVTCLSVSTDGSLLLSGSHDETVRLWDIQSKQCLKTMNHKGPVTNAFIVLAPANMLNPDGKPSVPLPKFSKHLYGTESTDEQGSEGVTLRLGLHQQVMGRRKALGEGLHGVRGDGVGFSPQPDCCEWAAAPWGLVSSPCAVGEGPGALLGCGVMFSGQWGFLQWAQGW", "length": 438, "header": "tr|A0A8V1AC74-1|A0A8V1AC74_CHICK Computationally mapped isoform of WD repeat-containing protein 18 OS=Gallus gallus OX=9031 GN=WDR18 PE=1 SV=1 CANONICAL=A0A8V1AGV9-1" }, "locus": { "chromosome": "28", "start_pos": 3316098, "end_pos": 3307230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066689.1", "url": "https://www.ensembl.org/id/ENSGALT00010066689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040830.1", "url": "https://www.ensembl.org/id/ENSGALP00010040830.1" } ] } }, { "isoform_ac": "A0A8V1AEV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9/entry#A0A8V1AEV2-1", "sequence": { "sequence": "MAAPMEVALVSDAAGPLCNCSVWELHSGSALPGYRGGNTGPRGLALLGGEHLLGAQLGKSYINVWELQRKDQLQQKIICPGPVTCLTASPNGLYILAGVAESIYLWEVSNGNLLAILNRHYQDLTCLCFTDDSSHFLSGAKDCLALVWNLYSVLQAEPSQIPDPRHVWSRHSLPITDMCCGFGGPLARAATASLDQTAKLWEVSSGELLLSVLFDVGIMAVTLDLSEYHMFCGGMDGSIFQVDLCAWPVQRDRTFQTERENGKIFKGHRNQVTCLSVSTDGSLLLSGSHDETVRLWDIQSKQCLKTMNHKGPVTNAFIVLAPANMLNPDGKPSVPLPKFSKHLYGTESTDEQGSEGVTLRLGLHQQASRHCRTLSPGRAIWRRLRRCTLRCAQRGKR", "length": 397, "header": "tr|A0A8V1AEV2-1|A0A8V1AEV2_CHICK Computationally mapped isoform of WD repeat-containing protein 18 OS=Gallus gallus OX=9031 GN=WDR18 PE=1 SV=1 CANONICAL=A0A8V1AGV9-1" }, "locus": { "chromosome": "28", "start_pos": 3317431, "end_pos": 3307230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066688.1", "url": "https://www.ensembl.org/id/ENSGALT00010066688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040829.1", "url": "https://www.ensembl.org/id/ENSGALP00010040829.1" } ] } }, { "isoform_ac": "A0A8V1AGV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9/entry#A0A8V1AGV9-1", "sequence": { "sequence": "MAAPMEVALVSDAAGPLCNCSVWELHSGSALPGYRGGNTGPRGLALLGGEHLLGAQLGKSYINVWELQRKDQLQQKIICPGPVTCLTASPNGLYILAGVAESIYLWEVSNGNLLAILNRHYQDLTCLCFTDDSSHFLSGAKDCLALVWNLYSVLQAEPSQIPDPRHVWSRHSLPITDMCCGFGGPLARAATASLDQTAKLWEVSSGELLLSVLFDVGIMAVTLDLSEYHMFCGGMDGSIFQVDLFQRDRTFQTERENGKIFKGHRNQVTCLSVSTDGSLLLSGSHDETVRLWDIQSKQCLKTMNHKGPVTNAFIVLAPANMLNPDGKPSVPLPKFSKHLYGTESTDEQGSEGVTLRLGLHQQESGESYLEKAEKMYSQMCSTREKNLMGDQEHLTIQVSELEEEVSTLRKINKNLFDFSARIITKPAK", "length": 428, "header": "tr|A0A8V1AGV9-1|A0A8V1AGV9_CHICK Isoform 1 of WD repeat-containing protein 18 OS=Gallus gallus OX=9031 GN=WDR18 PE=1 SV=1 CANONICAL=A0A8V1AGV9-1" }, "locus": { "chromosome": "28", "start_pos": 3317849, "end_pos": 3307230, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066691.1", "url": "https://www.ensembl.org/id/ENSGALT00010066691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040832.1", "url": "https://www.ensembl.org/id/ENSGALP00010040832.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "pmid": "" }, { "name": "dynein axonemal particle", "id": "GO:0120293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120293", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "pmid": "" }, { "name": "nuclear pre-replicative complex", "id": "GO:0005656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005656", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "pmid": "" }, { "name": "rixosome complex", "id": "GO:0120330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AGV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV9" }, { "id": "PF14077", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14077" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WD repeat-containing protein 18 C-terminal", "eco_id": "ECO_0000259", "start_pos": 379, "end_pos": 426, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL35-1", "uniprot_ac": "A0A8V1AL35", "uniprot_id": "A0A8V1AL35_CHICK", "mass": { "chemical_mass": 29759.0, "monoisotopic_mass": 29759.0 }, "refseq": {}, "gene_names": [ { "name": "SET", "type": "recommended", "evidence": [ { "id": "A0A8V1AL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35" } ] } ], "protein_names": [ { "name": "SET nuclear proto-onco", "type": "synonym", "evidence": [ { "id": 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] }, { "id": "A0A8V1A9H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPTRPQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGEDD", "length": 255, "header": "tr|A0A8V1AL35-1|A0A8V1AL35_CHICK Isoform 1 of SET nuclear proto-onco OS=Gallus gallus OX=9031 GN=SET PE=1 SV=1 CANONICAL=A0A8V1AL35-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35/entry#A0A8V1A9H8-1", "sequence": { "sequence": "MSAPAAKVSKKELNSNHDGADETSEKEQQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEVSA", "length": 273, "header": "tr|A0A8V1A9H8-1|A0A8V1A9H8_CHICK Computationally mapped isoform of SET nuclear proto-onco OS=Gallus gallus OX=9031 GN=SET PE=1 SV=1 CANONICAL=A0A8V1AL35-1" }, "locus": { "chromosome": "17", "start_pos": 5887545, "end_pos": 5882680, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069179.1", "url": "https://www.ensembl.org/id/ENSGALT00010069179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042621.1", "url": "https://www.ensembl.org/id/ENSGALP00010042621.1" } ] } }, { "isoform_ac": "A0A8V1AL35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35/entry#A0A8V1AL35-1", "sequence": { "sequence": "MGPTRPQEAIEHIDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVTTFVNHPQVSALLGEEDEEALHYLTRVEVTEFEDIKSGYRIDFYFDENPYFENKVLSKEFHLNESGDPSSKSTEIKWKSGKDLTKRSSQTQNKASRKRQHEEPESFFTWFTDHSDAGADELGEVIKDDIWPNPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGEDD", "length": 255, "header": "tr|A0A8V1AL35-1|A0A8V1AL35_CHICK Isoform 1 of SET nuclear proto-onco OS=Gallus gallus OX=9031 GN=SET PE=1 SV=1 CANONICAL=A0A8V1AL35-1" }, "locus": { "chromosome": "17", "start_pos": 5888492, "end_pos": 5882732, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069180.1", "url": "https://www.ensembl.org/id/ENSGALT00010069180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042622.1", "url": "https://www.ensembl.org/id/ENSGALP00010042622.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": 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"protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL35" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL35", "url": 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"A0A8V1AH47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFRLHESFPKPKRVCKEPPYKVEESGYAGFIMPIEVYFRNKEEPKKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTKEFRRKLIKAGGVMVMPEGAETVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKASKPHKVTKEHRERPRKDSESKNSSKDLEREQNKPLKDSSRKPTENKLPKEEKAPPKAAFKEPKLAVKETKLENTSPKGGPQPELKSSSKRPSNVESPKPSAKKQKKSSSKGVKNILGTSPRTSSSSYPEKKQTKEKMNAKVEKVKSESEAKEIKKPVEMEESNSEDENSFKSESSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDDDDSSSGEEAAVKANPVSRDSRLSLSDSDSDNSADSCLPSREPPSAQKLPPANNKASGRKSPESCNKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSYLEAVAT", "length": 551, "header": "tr|A0A8V1AJC4-1|A0A8V1AJC4_CHICK Isoform 1 of MLLT1 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT1 PE=4 SV=1 CANONICAL=A0A8V1AJC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4/entry#A0A8V1A9J8-1", "sequence": { "sequence": "MEAEGEHGRTKCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFRLHESFPKPKRVCKEPPYKVEESGYAGFIMPIEVYFRNKEEPKKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTKEFRRKLIKAGGVMVMPEGAETVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKASKPHKVTKEHRERPRKDSESKNSSKDLEREQNKPLKDSSRKPTENKLPKEEKAPPKAAFKEPKLAVKETKLENTSPKGGPQPELKSSSKRPSNVESPKPSAKKQKKSSSKGVKNILGTSPRTSSSSYPEKKQTKEKMNAKVEKVKSESEAKEIKKPVEMEESNSEDENSFKSESVQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDDDDSSSGEEAAVKANPVSRDSRLSLSDSDSDNSADSCLPSREPPSAQKLPPANNKASGRKSPESCNKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSYLEAVAT", "length": 561, "header": "tr|A0A8V1A9J8-1|A0A8V1A9J8_CHICK Computationally mapped isoform of MLLT1 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT1 PE=4 SV=1 CANONICAL=A0A8V1AJC4-1" }, "locus": { "chromosome": "28", "start_pos": 2119674, "end_pos": 2092452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069199.1", "url": "https://www.ensembl.org/id/ENSGALT00010069199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042641.1", "url": "https://www.ensembl.org/id/ENSGALP00010042641.1" } ] } }, { "isoform_ac": "A0A8V1AH47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4/entry#A0A8V1AH47-1", "sequence": { "sequence": "MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFRLHESFPKPKRVCKEPPYKVEESGYAGFIMPIEVYFRNKEEPKKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTKEFRRKLIKAGGVMVMPEGAETVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKASKPHKVTKEHRERPRKDSESKNSSKDLEREQNKPLKDSSRKPTENKLPKEEKAPPKAAFKEPKLAVKETKLENTSPKGGPQPELKSSSKRPSNVESPKPSAKKQKKSSSKGVKNILGTSPRTSSSSYPEKKQTKEKMNAKVEKVKSESEAKEIKKPVEMEESNSEDENSFKSESVQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDDDDSSSGEEAAVKANPVSRDSRLSLSDSDSDNSADSCLPSREPPSAQKLPPANNKASGRKSPESCNKPEKILKKGTYDKIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSYLEAVAT", "length": 530, "header": "tr|A0A8V1AH47-1|A0A8V1AH47_CHICK Computationally mapped isoform of MLLT1 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT1 PE=4 SV=1 CANONICAL=A0A8V1AJC4-1" }, "locus": { "chromosome": "28", "start_pos": 2118691, "end_pos": 2092452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069198.1", "url": "https://www.ensembl.org/id/ENSGALT00010069198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042640.1", "url": "https://www.ensembl.org/id/ENSGALP00010042640.1" } ] } }, { "isoform_ac": "A0A8V1AJC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4/entry#A0A8V1AJC4-1", "sequence": { "sequence": "MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFRLHESFPKPKRVCKEPPYKVEESGYAGFIMPIEVYFRNKEEPKKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTKEFRRKLIKAGGVMVMPEGAETVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKASKPHKVTKEHRERPRKDSESKNSSKDLEREQNKPLKDSSRKPTENKLPKEEKAPPKAAFKEPKLAVKETKLENTSPKGGPQPELKSSSKRPSNVESPKPSAKKQKKSSSKGVKNILGTSPRTSSSSYPEKKQTKEKMNAKVEKVKSESEAKEIKKPVEMEESNSEDENSFKSESSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDDDDSSSGEEAAVKANPVSRDSRLSLSDSDSDNSADSCLPSREPPSAQKLPPANNKASGRKSPESCNKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSYLEAVAT", "length": 551, "header": "tr|A0A8V1AJC4-1|A0A8V1AJC4_CHICK Isoform 1 of MLLT1 super elongation complex subunit OS=Gallus gallus OX=9031 GN=MLLT1 PE=4 SV=1 CANONICAL=A0A8V1AJC4-1" }, "locus": { "chromosome": "28", "start_pos": 2118691, "end_pos": 2092452, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069197.1", "url": "https://www.ensembl.org/id/ENSGALT00010069197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042639.1", "url": "https://www.ensembl.org/id/ENSGALP00010042639.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC4" }, { "id": "PS51037", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YEATS", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 138, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 524, "end_pos": 526 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AH84-1", "uniprot_ac": "A0A8V1AH84", "uniprot_id": "A0A8V1AH84_CHICK", "mass": { "chemical_mass": 32969.0, "monoisotopic_mass": 32969.0 }, "refseq": {}, "gene_names": [ { "name": "PHYHD1", "type": "recommended", "evidence": [ { "id": "A0A8V1AH84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84" } ] } ], "protein_names": [ { "name": "Phytanoyl-CoA dioxygenase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AH84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "2-oxoglutarate(2OG)-dependent dioxygenase that catalyzes the conversion of 2-oxoglutarate to succinate and CO(2) in an iron-dependent manner. However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism. Does not show detectable activity towards fatty acid CoA thioesters.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A9N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N4#function" }, { "database": "UniProtKB", "id": "ARBA00045487", "url": "https://www.uniprot.org/uniprotkb/ARBA00045487#function" }, { "database": "UniProtKB", "id": "A0A8V1AEW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW9#function" }, { "database": "UniProtKB", "id": "A0A8V1AEX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX5#function" }, { "database": "UniProtKB", "id": "A0A8V1AH84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84#function" }, { "database": "UniProtKB", "id": "A0A8V1AJF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHYHD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84", "locus": { "chromosome": "17", "start_pos": 6001785, "end_pos": 5993882, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028589", "url": "https://www.ensembl.org/id/ENSGALG00010028589" } ] } } ], "crossref": [ { "id": "A0A8V1AH84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AH84", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9N4", "url": "https://www.orthodb.org/?gene=A0A8V1A9N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEW9", "url": "https://www.orthodb.org/?gene=A0A8V1AEW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEX5", "url": "https://www.orthodb.org/?gene=A0A8V1AEX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH84", "url": "https://www.orthodb.org/?gene=A0A8V1AH84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJF4", "url": "https://www.orthodb.org/?gene=A0A8V1AJF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20883:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20883:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05721", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05721", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1A9N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASVTQHQMQKFREDGFLVLEHFFSPEECDSMRSSIQRILDGMEVPPHCRTEFSTKEEEQLQAQMQGSSDYFLTSGDKIRFFFEKGVLDERGNFLIAKEKSVSKIGHALHAHDPVFKQITHSSKVQELGRKLGLERPVVVQSMYIFKQPGIGGEVTPHQDATFLHTEPLGRVLGFWIALEDATQENGCLWFIPGSHTSGITRRMVRAAQGASTCVEFVGSEPAYDDSKFIPVPISKGGLIVIHGEVVHKSAMNSSAFSRHVYTFHVMEAEGTNWSKENWLQPTPELPFPPLYT", "length": 293, "header": "tr|A0A8V1AH84-1|A0A8V1AH84_CHICK Isoform 1 of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PHYHD1 PE=1 SV=1 CANONICAL=A0A8V1AH84-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84/entry#A0A8V1A9N4-1", "sequence": { "sequence": "MASVTQHQMQKFREDGFLVLEHFFSPEECDSMRSSIQRILDGMEVPPHCRTEFSTKEEEQLQAQGSSDYFLTSGDKIRFFFEKGVLDERGNFLIAKEKSVSKIGHALHAHDPVFKQITHSSKVQQPGIGGEVTPHQDATFLHTEPLGRVLGFWIALEDATQENGCLWFIPGSHTSGITRRMVRAAQGASTCVEFVGSEPAYDDSKFIPVPISKGGLIVIHGEVVHKSAMNSSAFSRHVYTFHVMEAEGTNWSKENWLQPTPELPFPPLYT", "length": 270, "header": "tr|A0A8V1A9N4-1|A0A8V1A9N4_CHICK Computationally mapped isoform of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PHYHD1 PE=1 SV=1 CANONICAL=A0A8V1AH84-1" }, "locus": { "chromosome": "17", "start_pos": 6000556, "end_pos": 5995397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069235.1", "url": "https://www.ensembl.org/id/ENSGALT00010069235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042677.1", "url": "https://www.ensembl.org/id/ENSGALP00010042677.1" } ] } }, { "isoform_ac": "A0A8V1AEW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84/entry#A0A8V1AEW9-1", "sequence": { "sequence": "MSEIPQEEGSHPMSPFQFREDGFLVLEHFFSPEECDSMRSSIQRILDGMEVPPHCRTEFSTKEEEQLQAQGSSDYFLTSGDKIRFFFEKGVLDERALHAHDPVFKQITHSSKVQELGRKLGLERPVVVQSMYIFKQPGIGGEVTPHQDATFLHTEPLGRVLGFWIALEDATQENGCLWFIPGSHTSGITRRMVRAAQGASTCVEFVGSEPAYDDSKFIPVPISKGGLIVIHGEVVHKSAMNSSAFSRHVYTFHVMEAEGTNWSKENWLQPTPELPFPPLYT", "length": 281, "header": "tr|A0A8V1AEW9-1|A0A8V1AEW9_CHICK Computationally mapped isoform of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PHYHD1 PE=1 SV=1 CANONICAL=A0A8V1AH84-1" }, "locus": { "chromosome": "17", "start_pos": 6000556, "end_pos": 5996132, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069232.1", "url": "https://www.ensembl.org/id/ENSGALT00010069232.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042674.1", "url": "https://www.ensembl.org/id/ENSGALP00010042674.1" } ] } }, { "isoform_ac": "A0A8V1AEX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84/entry#A0A8V1AEX5-1", "sequence": { "sequence": "MASVTQHQMQKFREDGFLVLEHFFSPEECDSMRSSIQRILDGMEVPPHCRTEFSTKEEEQLQAQGSSDYFLTSGDKIRFFFEKGVLDERGNFLIAKEKSVSKIGHALHAHDPVFKQITHSSKVQDRIPTENSALWCAESSKRELWKVSFQELGRKLGLERPVVVQSMYIFKQPGIGGEVTPHQDATFLHTEPLGRVLGFWIALEDATQENGCLWFIPGSHTSGITRRMVRAAQGASTCVEFVGSEPAYDDSKFIPVPISKGGLIVIHGEVVHKSAMNSSAFSRHVYTFHVMEAEGTNWSKENWLQPTPELPFPPLYT", "length": 317, "header": "tr|A0A8V1AEX5-1|A0A8V1AEX5_CHICK Computationally mapped isoform of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PHYHD1 PE=1 SV=1 CANONICAL=A0A8V1AH84-1" }, "locus": { "chromosome": "17", "start_pos": 6000556, "end_pos": 5995397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069237.1", "url": "https://www.ensembl.org/id/ENSGALT00010069237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042679.1", "url": "https://www.ensembl.org/id/ENSGALP00010042679.1" } ] } }, { "isoform_ac": "A0A8V1AH84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84/entry#A0A8V1AH84-1", "sequence": { "sequence": "MASVTQHQMQKFREDGFLVLEHFFSPEECDSMRSSIQRILDGMEVPPHCRTEFSTKEEEQLQAQMQGSSDYFLTSGDKIRFFFEKGVLDERGNFLIAKEKSVSKIGHALHAHDPVFKQITHSSKVQELGRKLGLERPVVVQSMYIFKQPGIGGEVTPHQDATFLHTEPLGRVLGFWIALEDATQENGCLWFIPGSHTSGITRRMVRAAQGASTCVEFVGSEPAYDDSKFIPVPISKGGLIVIHGEVVHKSAMNSSAFSRHVYTFHVMEAEGTNWSKENWLQPTPELPFPPLYT", "length": 293, "header": "tr|A0A8V1AH84-1|A0A8V1AH84_CHICK Isoform 1 of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PHYHD1 PE=1 SV=1 CANONICAL=A0A8V1AH84-1" }, "locus": { "chromosome": "17", "start_pos": 6000556, "end_pos": 5995397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069239.1", "url": "https://www.ensembl.org/id/ENSGALT00010069239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042681.1", "url": "https://www.ensembl.org/id/ENSGALP00010042681.1" } ] } }, { "isoform_ac": "A0A8V1AJF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84/entry#A0A8V1AJF4-1", "sequence": { "sequence": "MASVTQHQMQKFREDGFLVLEHFFSPEECDSMRSSIQRILDGMEVPPHCRTEFSTKEEEQLQAQGSSDYFLTSGDKIRFFFEKGVLDERGNFLIAKEKSVSKIGHALHAHDPVFKQITHSSKVQELGRKLGLERPVVVQSMYIFKQPGIGGEVTPHQDATFLHTEPLGRVLGFWIALEDATQENGCLWFIPGSHTSGITRRMVRAAQGASTCVEFVGSEPAYDDSKFIPVPISKGGLIVIHGEVVHKSAMNSSAFSRHVYTFHVMEAEGTNWSKENCCTLVRLQAS", "length": 286, "header": "tr|A0A8V1AJF4-1|A0A8V1AJF4_CHICK Computationally mapped isoform of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PHYHD1 PE=1 SV=1 CANONICAL=A0A8V1AH84-1" }, "locus": { "chromosome": "17", "start_pos": 6000146, "end_pos": 5995397, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069233.1", "url": "https://www.ensembl.org/id/ENSGALT00010069233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042675.1", "url": "https://www.ensembl.org/id/ENSGALP00010042675.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 283, "start_aa": "Thr", "end_pos": 283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84" } ], "pmid": "" }, { "name": "2-oxoglutarate-dependent dioxygenase activity", "id": "GO:0016706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AH84", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 283 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 }, { "start_pos": 273, "end_pos": 275 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AHS2-1", "uniprot_ac": "A0A8V1AHS2", "uniprot_id": "A0A8V1AHS2_CHICK", "mass": { "chemical_mass": 38623.0, "monoisotopic_mass": 38623.0 }, "refseq": {}, "gene_names": [ { "name": "GFI1B", "type": "recommended", "evidence": [ { "id": "A0A8V1AHS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ] } ], "protein_names": [ { "name": "Growth factor independent 1B transcriptional repressor", "type": "synonym", "evidence": [ { "id": "A0A8V1AHS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GFI1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2", "locus": { "chromosome": "17", "start_pos": 7370891, "end_pos": 7359746, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028823", "url": "https://www.ensembl.org/id/ENSGALG00010028823" } ] } } ], "crossref": [ { "id": "A0A8V1AHS2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AHS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "395977", "url": "https://www.ncbi.nlm.nih.gov/gene/395977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395977", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395977", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECPVPQG", "url": "https://omabrowser.org/oma/group/ECPVPQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAA8", "url": "https://www.orthodb.org/?gene=A0A8V1AAA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHS2", "url": "https://www.orthodb.org/?gene=A0A8V1AHS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990422", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRSFLVKSKKAHTYHQHRFVEDDLPIFTWDPITSAFTAAGDRDKTPEDGKKQDLEWVVPKQEKDSFQPKEESVPVQYLSRMLPGPSAQDVSISGLQVKDCTNPTSVPTFYKTGFSWDAFQLPYSYRQMSSTMQSALLEHPVSLYGSHLLPSAEPPLDYSMRYSSDMETYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACEVCGKTFGHAVSLEQHTNIHSQERSFECKMCGKTFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCAKGFQRKVDLRRHRETQHSLK", "length": 337, "header": "tr|A0A8V1AHS2-1|A0A8V1AHS2_CHICK Isoform 1 of Growth factor independent 1B transcriptional repressor OS=Gallus gallus OX=9031 GN=GFI1B PE=4 SV=1 CANONICAL=A0A8V1AHS2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2/entry#A0A8V1AAA8-1", "sequence": { "sequence": "MLQLSEKVEGAQREDDVSLGAHPGRSQGKSSSEWKMPRSFLVKSKKAHTYHQHRFVEDDLPIFTWDPITSAFTAAGDRDKTPEDGKKQDLEWVVPKQEKDSFQPKEESVPVQYLSRMLPGPSAQDVSISGLQVKDCTNPTSVPTFYKTGFSWDAFQLPYSYRQMSSTMQSALLEHPVSLYGSHLLPSAEPPLDYSMRYSSDMETYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACEVCGKTFGHAVSLEQHTNIHSQERSFECKMCGKTFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCAKGFQRKVDLRRHRETQHSLK", "length": 372, "header": "tr|A0A8V1AAA8-1|A0A8V1AAA8_CHICK Computationally mapped isoform of Growth factor independent 1B transcriptional repressor OS=Gallus gallus OX=9031 GN=GFI1B PE=4 SV=1 CANONICAL=A0A8V1AHS2-1" }, "locus": { "chromosome": "17", "start_pos": 7368786, "end_pos": 7359783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069721.1", "url": "https://www.ensembl.org/id/ENSGALT00010069721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042912.1", "url": "https://www.ensembl.org/id/ENSGALP00010042912.1" } ] } }, { "isoform_ac": "A0A8V1AHS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2/entry#A0A8V1AHS2-1", "sequence": { "sequence": "MPRSFLVKSKKAHTYHQHRFVEDDLPIFTWDPITSAFTAAGDRDKTPEDGKKQDLEWVVPKQEKDSFQPKEESVPVQYLSRMLPGPSAQDVSISGLQVKDCTNPTSVPTFYKTGFSWDAFQLPYSYRQMSSTMQSALLEHPVSLYGSHLLPSAEPPLDYSMRYSSDMETYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACEVCGKTFGHAVSLEQHTNIHSQERSFECKMCGKTFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCAKGFQRKVDLRRHRETQHSLK", "length": 337, "header": "tr|A0A8V1AHS2-1|A0A8V1AHS2_CHICK Isoform 1 of Growth factor independent 1B transcriptional repressor OS=Gallus gallus OX=9031 GN=GFI1B PE=4 SV=1 CANONICAL=A0A8V1AHS2-1" }, "locus": { "chromosome": "17", "start_pos": 7368786, "end_pos": 7364866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069720.1", "url": "https://www.ensembl.org/id/ENSGALT00010069720.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042911.1", "url": "https://www.ensembl.org/id/ENSGALP00010042911.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395977", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395977", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XL46-1", "protein_name": "Growth factor independent 1B transcriptional repressor", "gene_name": "Gfi1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRSFLVKSKKAHTYHQPRAQGDDLVWPPAVIPVAKEHTQSGSPVLSTLLPSQTLDWSAVKQKQEMLLNQSLPKMASAPEGPHVTSQPQDGESPLSESPPFYKPSFSWDTLASSYRHSYQQTPSTMQSAFLERSVRLYGSPLVPSTESPLDFSLRYSPGMDTYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQGVPARSSPSPSLAVPGLEAPPAPDPPRPRFLRQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK", "length": 363 }, "evidence": [ { "id": "A0A8V1AHS2", "url": "https://omabrowser.org/oma/group/A0A8V1AHS2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7G7Q7-1", "protein_name": "Zinc finger protein Gfi-1b", "gene_name": "Gfi1b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPRSFLVKSKKAHTYHQPRAQDDDLVWPPAVIPVVKEHILSSSPVLGTLLPSQTLDWNIVKQEQEMLLDQNLPKMASAPEGPLVTSQPQDGESPVSESPPFYKPSFSWDTLASSYNHSYQQTPSTMQSAFLERSVRLYGSPLVPSTESPLDFSLRYSPGMDTYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDVCGKTFGHAVSLEQHTHVHSQGVPTGSSPVPSLAVPGLEAPPAPDPPGPRFLRQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK", "length": 363 }, "evidence": [ { "id": "A0A8V1AHS2", "url": "https://omabrowser.org/oma/group/A0A8V1AHS2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SYB3-1", "protein_name": "Growth factor independent 1B transcriptional repressor", "gene_name": "GFI1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPRSFLVKSKKAHTYHQPRTREDELLWPLALGPVARDQVPSISPVLSSLFPNQRLDWTDLKREPQLELEQSSMTRLASGPEGPAVTSRPQDGDSPSSDSPPFYKPSFSWDTLASSYGHSYRQAPSTMQSAFLERSVSLYGSPLVPSAEPPLDFSLHYSPGMDAYHCIKCSKVFSTPHGLEVHARRSHSGTRPFACNVCGKTFGHSVSLEQHTHVHSQATPTECPVPQGIPAGSSPAPTPDPPGPRFLRQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCAKGFQRKVDLRRHRESQHNLK", "length": 363 }, "evidence": [ { "id": "A0A8V1AHS2", "url": "https://omabrowser.org/oma/group/A0A8V1AHS2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5VTD9-1", "protein_name": "Zinc finger protein Gfi-1b", "gene_name": "GFI1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAPAPEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK", "length": 330 }, "evidence": [ { "id": "A0A8V1AHS2", "url": "https://omabrowser.org/oma/group/A0A8V1AHS2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "regulation of hemopoiesis", "id": "GO:1903706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AHS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHS2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 198, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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[], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AK54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VAV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54", "locus": { "chromosome": "17", "start_pos": 7654447, "end_pos": 7754765, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028884", "url": "https://www.ensembl.org/id/ENSGALG00010028884" } ] } } ], "crossref": [ { "id": "A0A8V1AK54", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AK54", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01223", "url": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAH7", "url": "https://www.orthodb.org/?gene=A0A8V1AAH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFV3", "url": "https://www.orthodb.org/?gene=A0A8V1AFV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHX6", "url": "https://www.orthodb.org/?gene=A0A8V1AHX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK54", "url": "https://www.orthodb.org/?gene=A0A8V1AK54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALX4", "url": "https://www.orthodb.org/?gene=A0A8V1ALX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALX8", "url": "https://www.orthodb.org/?gene=A0A8V1ALX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45818:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45818:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11971", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11971", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2424491", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2424491", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871796", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2871809", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2871809", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3928665", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928665", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-445144", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445144", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5218920", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218920", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013026", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013106", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9748787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9748787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9958810", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9958810", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AAH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSDLFDPFDLFDVRDFGKVISAVSRLSFHSIAQTKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIRVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLTPQDMEAIFINLEDLIKVHFNFLRAIDVSMMSGGSSLAKVFLEFKERLLIYGKYCSHMEYAQNTLNHLIANRDDVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSSDRPEKQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYNYELKEIIELLFHKMTDDPMNNKDIKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEEMKRKWMEQFEMAMSNIKPEKANANHHSFQMYTFEKTTNCKACKMFLRGTFYQGYLCPKCGAGAHKECLEIIPPCKMGSSADQDLLSAGPGPKMVAVQNYHGNPAPPGKPVLTFQIGDVIELLRGDPDSPWWEGRLLQTKKSGYFPSSSVKPCPVDARPPNSRPPSREIDYTVYPWFAGNMERQQTDNLLKAHVSGTYLIRERPAEAERFAISIKFNEEVKHIKVVEKDNWIHITEAKKFESLLELVEYYQNHSLKESFKQLDTTLKYPYKSRERSTSRTFTRSPASCASYNFSFLSPQGLNFSSQSSSSPFWSVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRVGWFPSTYVEEEGVQ", "length": 878, "header": "tr|A0A8V1AK54-1|A0A8V1AK54_CHICK Isoform 1 of Vav guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=VAV2 PE=1 SV=1 CANONICAL=A0A8V1AK54-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54/entry#A0A8V1AAH7-1", "sequence": { "sequence": "MRWRSRRAPVLLWEETDLESKSFPRKMKKNGRAPPHIPVSRSPFPHRGRRCSGRSALLPSAFPLLAALPAVPIAIPMSRRVLPSSCPAPAPTRTYGNWKALGFRPLELFSVSDCFDGGEPQTGSGCFGFECPAVFFACRAVRYLHGSRETKSIANSKPCSPVPCAEDPSFLCLKNIRTFLKVCHDKFGLRNSDLFDPFDLFDVRDFGKVISAVSRLSFHSIAQTKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIRVEVQQPMKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLTPQDMEAIFINLEDLIKVHFNFLRAIDVSMMSGGSSLAKVFLEFKERLLIYGKYCSHMEYAQNTLNHLIANRDDVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSSDRPEKQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYNYELKEIIELLFHKMTDDPMNNKDIKKWSYGFYLIHLQGKQGFQFFCKTEEMKRKWMEQFEMAMSNIKPEKANANHHSFQMYTFEKTTNCKACKMFLRGTFYQGYLCPKCGAGAHKECLEIIPPCKMGSSADQDLLSAGPGPKMVAVQNYHGNPAPPGKPVLTFQIGDVIELLRGDPDSPWWEGRLLQTKKSGYFPSSSVKPCPVDARPPNSRPPSREIDYTVYPWFAGNMERQQTDNLLKAHVSGTYLIRERPAEAERFAISIKFNEEVKHIKVVEKDNWIHITEAKKFESLLELVEYYQNHSLKESFKQLDTTLKYPYKSRERSTSRTFTRSPVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRVGWFPSTYVEEEGVQ", "length": 940, "header": "tr|A0A8V1AAH7-1|A0A8V1AAH7_CHICK Computationally mapped isoform of Vav guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=VAV2 PE=1 SV=1 CANONICAL=A0A8V1AK54-1" }, "locus": { "chromosome": "17", "start_pos": 7753885, "end_pos": 7656905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069858.1", "url": "https://www.ensembl.org/id/ENSGALT00010069858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042984.1", "url": "https://www.ensembl.org/id/ENSGALP00010042984.1" } ] } }, { "isoform_ac": "A0A8V1AFV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54/entry#A0A8V1AFV3-1", "sequence": { "sequence": "MEEWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSDLFDPFDLFDVRDFGKVISAVSRLSFHSIAQTKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIRVEVQQPMKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLTPQDMEAIFINLEDLIKVHFNFLRAIDVSMMSGGSSLAKVFLEFKERLLIYGKYCSHMEYAQNTLNHLIANRDDVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSSDRPEKQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYNYELKEIIELLFHKMTDDPMNNKDIKKWSYGFYLIHLQGKQGFQFFCKTEEMKRKWMEQFEMAMSNIKPEKANANHHSFQMYTFEKTTNCKACKMFLRGTFYQGYLCPKCGAGAHKECLEIIPPCKMGSSADQDLLSAGPGPKMVAVQNYHGNPAPPGKPVLTFQIGDVIELLRGDPDSPWWEPPNSRPPSREIDYTVYPWFAGNMERQQTDNLLKAHVSGTYLIRERPAEAERFAISIKFNEEVKHIKVVEKDNWIHITEAKKFESLLELVEYYQNHSLKESFKQLDTTLKYPYKSRERSTSRTFTRSPVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRVGWFPSTYVEEEGVQ", "length": 814, "header": "tr|A0A8V1AFV3-1|A0A8V1AFV3_CHICK Computationally mapped isoform of Vav guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=VAV2 PE=1 SV=1 CANONICAL=A0A8V1AK54-1" }, "locus": { "chromosome": "17", "start_pos": 7754393, "end_pos": 7656905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069855.1", "url": "https://www.ensembl.org/id/ENSGALT00010069855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042981.1", "url": "https://www.ensembl.org/id/ENSGALP00010042981.1" } ] } }, { "isoform_ac": "A0A8V1AHX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54/entry#A0A8V1AHX6-1", "sequence": { "sequence": "MEEWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSDLFDPFDLFDVRDFGKVISAVSRLSFHSIAQTKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIRVEVQQPMKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLTPQDMEAIFINLEDLIKVHFNFLRAIDVSMMSGGSSLAKVFLEFKERLLIYGKYCSHMEYAQNTLNHLIANRDDVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSSDRPEKQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYNYELKEIIELLFHKMTDDPMNNKDIKKWSYGFYLIHLQGKQGFQFFCKTEEMKRKWMEQFEMAMSNIKPEKANANHHSFQMYTFEKTTNCKACKMFLRGTFYQGYLCPKCGAGAHKECLEIIPPCKMGELLGPDLLSAGPGPKMVAVQNYHGNPAPPGKPVLTFQIGDVIELLRGDPDSPWWEGRLLQTKKSGYFPSSSVKPCPVDARPPNSRPPSREIDYTVYPWFAGNMERQQTDNLLKAHVSGTYLIRERPAEAERFAISIKFNEEVKHIKVVEKDNWIHITEAKKFESLLELVEYYQNHSLKESFKQLDTTLKYPYKSRERSTSRTFTRSPVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRVGWFPSTYVEEEGVQ", "length": 839, "header": "tr|A0A8V1AHX6-1|A0A8V1AHX6_CHICK Computationally mapped isoform of Vav guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=VAV2 PE=1 SV=1 CANONICAL=A0A8V1AK54-1" }, "locus": { "chromosome": "17", "start_pos": 7754393, "end_pos": 7656905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069857.1", "url": "https://www.ensembl.org/id/ENSGALT00010069857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042983.1", "url": "https://www.ensembl.org/id/ENSGALP00010042983.1" } ] } }, { "isoform_ac": "A0A8V1AK54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54/entry#A0A8V1AK54-1", "sequence": { "sequence": "MEEWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSDLFDPFDLFDVRDFGKVISAVSRLSFHSIAQTKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIRVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLTPQDMEAIFINLEDLIKVHFNFLRAIDVSMMSGGSSLAKVFLEFKERLLIYGKYCSHMEYAQNTLNHLIANRDDVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSSDRPEKQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYNYELKEIIELLFHKMTDDPMNNKDIKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEEMKRKWMEQFEMAMSNIKPEKANANHHSFQMYTFEKTTNCKACKMFLRGTFYQGYLCPKCGAGAHKECLEIIPPCKMGSSADQDLLSAGPGPKMVAVQNYHGNPAPPGKPVLTFQIGDVIELLRGDPDSPWWEGRLLQTKKSGYFPSSSVKPCPVDARPPNSRPPSREIDYTVYPWFAGNMERQQTDNLLKAHVSGTYLIRERPAEAERFAISIKFNEEVKHIKVVEKDNWIHITEAKKFESLLELVEYYQNHSLKESFKQLDTTLKYPYKSRERSTSRTFTRSPASCASYNFSFLSPQGLNFSSQSSSSPFWSVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRVGWFPSTYVEEEGVQ", "length": 878, "header": "tr|A0A8V1AK54-1|A0A8V1AK54_CHICK Isoform 1 of Vav guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=VAV2 PE=1 SV=1 CANONICAL=A0A8V1AK54-1" }, "locus": { "chromosome": "17", "start_pos": 7754393, "end_pos": 7656905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069856.1", "url": "https://www.ensembl.org/id/ENSGALT00010069856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042982.1", "url": "https://www.ensembl.org/id/ENSGALP00010042982.1" } ] } }, { "isoform_ac": "A0A8V1ALX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54/entry#A0A8V1ALX4-1", "sequence": { "sequence": "MWFDFICPAGGEQCPLNRFEKLLSASQVISAVSRLSFHSIAQTKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIRVEVQQPMKMGMTEDDKRNCCLLEIQETEAKYYKTLEDIEKNYMNPLKLVLTPQDMEAIFINLEDLIKVHFNFLRAIDVSMMSGGSSLAKVFLEFKERLLIYGKYCSHMEYAQNTLNHLIANRDDVRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSSDRPEKQQLKEALEAMQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYNYELKEIIELLFHKMTDDPMNNKDIKKWSYGFYLIHLQGKQGFQFFCKTEEMKRKWMEQFEMAMSNIKPEKANANHHSFQMYTFEKTTNCKACKMFLRGTFYQGYLCPKCGAGAHKECLEIIPPCKMGSSADQDLLSAGPGPKMVAVQNYHGNPAPPGKPVLTFQIGDVIELLRGDPDSPWWEGRLLQTKKSGYFPSSSVKPCPVDARPPNSRPPSREIDYTVYPWFAGNMERQQTDNLLKAHVSGTYLIRERPAEAERFAISIKFNEEVKHIKVVEKDNWIHITEAKKFESLLELVEYYQNHSLKESFKQLDTTLKYPYKSRERSTSRTFTRSPVFTPRVIGTAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGETNGRVGWFPSTYVEEEGVQ", "length": 759, "header": "tr|A0A8V1ALX4-1|A0A8V1ALX4_CHICK Computationally mapped isoform of Vav guanine nucleotide exchange factor 2 OS=Gallus gallus OX=9031 GN=VAV2 PE=1 SV=1 CANONICAL=A0A8V1AK54-1" }, "locus": { "chromosome": "17", "start_pos": 7726602, "end_pos": 7656905, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069854.1", "url": "https://www.ensembl.org/id/ENSGALT00010069854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042980.1", "url": "https://www.ensembl.org/id/ENSGALP00010042980.1" } ] } }, { "isoform_ac": "A0A8V1ALX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK54/entry#A0A8V1ALX8-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758136" } ] }, { "annotation": "Monocarboxylate transporter selective for taurine. May associate with BSG/CD147 or EMB/GP70 ancillary proteins to mediate facilitative efflux or influx of taurine across the plasma membrane. The transport is pH- and sodium-independent. Rather low-affinity, is likely effective for taurine transport in tissues where taurine is present at high concentrations.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ9#function" }, { "database": "UniProtKB", "id": "ARBA00058516", "url": "https://www.uniprot.org/uniprotkb/ARBA00058516#function" }, { "database": "UniProtKB", "id": "A0A8V1ACQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACQ0#function" }, { "database": "UniProtKB", "id": "A0A8V1AI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC16A6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09", "locus": { "chromosome": "18", "start_pos": 8430463, "end_pos": 8439811, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029386", "url": "https://www.ensembl.org/id/ENSGALG00010029386" } ] } } ], "crossref": [ { "id": "A0A8V1AI09", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AI09", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17422", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17422", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417435", "url": "https://www.ncbi.nlm.nih.gov/gene/417435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417435", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFFCGVQ", "url": "https://omabrowser.org/oma/group/TFFCGVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACQ0", "url": "https://www.orthodb.org/?gene=A0A8V1ACQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI09", "url": "https://www.orthodb.org/?gene=A0A8V1AI09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALZ9", "url": "https://www.orthodb.org/?gene=A0A8V1ALZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANI7", "url": "https://www.orthodb.org/?gene=A0A8V1ANI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046758136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758136", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "66328", "url": "https://www.rhea-db.org/rhea/66328", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVKAVKMPCTTPNVYTKVPDGGWGWAIAVAFFFVEALTYGVIKSFGVFFNDLMESFDETNSRISWIISICVFVQTFTAPLSTVLTNRFGHRFVVMAGGVLVSTGMITASFARSVVHMYITIGIISGLGYCLSFLPTVTILSQYFDKRRSLVTAVASTGECFAVFLFAPVNTHLKEQIGWRYSLLFVGALQLSIVICGSLLRPMIIKEQEEEEEVKVQPPEEPAETKYMLENEQTRTSIESIDSGVEITTSPKNVPGNTKAEPKSEEPKDHVQITVENNSTPTEPKTKLLDFSVMRDYSFICYAFFGLFATLGFFAPSLYVIPLSRSLGISKDHSAYILSAMAIAEVLGRISAGWVLNREPIRKIHIELICVILLSVALFAFPFASEFWGLMTCSIFFGFMLGTVAGTHIPLLAEDDVVGIARMSSAAGVYVFIQSFSGLAGPPLAGVIVDRTQNYSSAFYSCAAGTVMGAVFLSLVRPCKVGMCHQQPAGAEGSVVEGTQDSPEDFIDMDIGKADHSGKGSDSVA", "length": 526, "header": "tr|A0A8V1AI09-1|A0A8V1AI09_CHICK Isoform 1 of Monocarboxylate transporter 7 OS=Gallus gallus OX=9031 GN=SLC16A6 PE=4 SV=1 CANONICAL=A0A8V1AI09-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09/entry#A0A8V1ACQ0-1", "sequence": { "sequence": "MRELGSPAAVLLGYRSEMTVKAVKMPCTTPNVYTKVPDGGWGWAIAVAFFFVEALTYGVIKSFGVFFNDLMESFDETNSRISWIISICVFVQTFTAPLSTVLTNRFGHRFVVMAGGVLVSTGMITASFARSVVHMYITIGIISGLGYCLSFLPTVTILSQYFDKRRSLVTAVASTGECFAVFLFAPVNTHLKEQIGWRYSLLFVGALQLSIVICGSLLRPMIIKEQEEEEEVKVQPPEEPAETKYMLENEQTRTSIESIDSGVEITTSPKNVPGNTKAEPKSEEPKDHVQITVENNSTPTEPKTKLLDFSVMRDYSFICYAFFGLFATLGFFAPSLYVIPLSRSLGISKDHSAYILSAMAIAEVLGRISAGWVLNREPIRKIHIELICVILLSVALFAFPFASEFWGLMTCSIFFGFMLGTVAGTHIPLLAEDDVVGIARMSSAAGVYVFIQSFSGLAGPPLAGVIVDRTQNYSSAFYSCAAGTVMGAVFLSLVRPCKVGMCHQQPAGAEGSVVEGTQDSPEDFIDMDIGKADHSGKGSDSVA", "length": 543, "header": "tr|A0A8V1ACQ0-1|A0A8V1ACQ0_CHICK Computationally mapped isoform of Monocarboxylate transporter 7 OS=Gallus gallus OX=9031 GN=SLC16A6 PE=4 SV=1 CANONICAL=A0A8V1AI09-1" }, "locus": { "chromosome": "18", "start_pos": 8437538, "end_pos": 8432638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071074.1", "url": "https://www.ensembl.org/id/ENSGALT00010071074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043765.1", "url": "https://www.ensembl.org/id/ENSGALP00010043765.1" } ] } }, { "isoform_ac": "A0A8V1AI09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09/entry#A0A8V1AI09-1", "sequence": { "sequence": "MTVKAVKMPCTTPNVYTKVPDGGWGWAIAVAFFFVEALTYGVIKSFGVFFNDLMESFDETNSRISWIISICVFVQTFTAPLSTVLTNRFGHRFVVMAGGVLVSTGMITASFARSVVHMYITIGIISGLGYCLSFLPTVTILSQYFDKRRSLVTAVASTGECFAVFLFAPVNTHLKEQIGWRYSLLFVGALQLSIVICGSLLRPMIIKEQEEEEEVKVQPPEEPAETKYMLENEQTRTSIESIDSGVEITTSPKNVPGNTKAEPKSEEPKDHVQITVENNSTPTEPKTKLLDFSVMRDYSFICYAFFGLFATLGFFAPSLYVIPLSRSLGISKDHSAYILSAMAIAEVLGRISAGWVLNREPIRKIHIELICVILLSVALFAFPFASEFWGLMTCSIFFGFMLGTVAGTHIPLLAEDDVVGIARMSSAAGVYVFIQSFSGLAGPPLAGVIVDRTQNYSSAFYSCAAGTVMGAVFLSLVRPCKVGMCHQQPAGAEGSVVEGTQDSPEDFIDMDIGKADHSGKGSDSVA", "length": 526, "header": "tr|A0A8V1AI09-1|A0A8V1AI09_CHICK Isoform 1 of Monocarboxylate transporter 7 OS=Gallus gallus OX=9031 GN=SLC16A6 PE=4 SV=1 CANONICAL=A0A8V1AI09-1" }, "locus": { "chromosome": "18", "start_pos": 8436948, "end_pos": 8432638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071076.1", "url": "https://www.ensembl.org/id/ENSGALT00010071076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043767.1", "url": "https://www.ensembl.org/id/ENSGALP00010043767.1" } ] } }, { "isoform_ac": "A0A8V1ALZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09/entry#A0A8V1ALZ9-1", "sequence": { "sequence": "MLNAAPQRSEMTVKAVKMPCTTPNVYTKVPDGGWGWAIAVAFFFVEALTYGVIKSFGVFFNDLMESFDETNSRISWIISICVFVQTFTAPLSTVLTNRFGHRFVVMAGGVLVSTGMITASFARSVVHMYITIGIISGLGYCLSFLPTVTILSQYFDKRRSLVTAVASTGECFAVFLFAPVNTHLKEQIGWRYSLLFVGALQLSIVICGSLLRPMIIKEQEEEEEVKVQPPEEPAETKYMLENEQTRTSIESIDSGVEITTSPKNVPGNTKAEPKSEEPKDHVQITVENNSTPTEPKTKLLDFSVMRDYSFICYAFFGLFATLGFFAPSLYVIPLSRSLGISKDHSAYILSAMAIAEVLGRISAGWVLNREPIRKIHIELICVILLSVALFAFPFASEFWGLMTCSIFFGFMLGTVAGTHIPLLAEDDVVGIARMSSAAGVYVFIQSFSGLAGPPLAGVIVDRTQNYSSAFYSCAAGTVMGAVFLSLVRPCKVGMCHQQPAGAEGSVVEGTQDSPEDFIDMDIGKADHSGKGSDSVA", "length": 536, "header": "tr|A0A8V1ALZ9-1|A0A8V1ALZ9_CHICK Computationally mapped isoform of Monocarboxylate transporter 7 OS=Gallus gallus OX=9031 GN=SLC16A6 PE=4 SV=1 CANONICAL=A0A8V1AI09-1" }, "locus": { "chromosome": "18", "start_pos": 8439612, "end_pos": 8432638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071077.1", "url": "https://www.ensembl.org/id/ENSGALT00010071077.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043768.1", "url": "https://www.ensembl.org/id/ENSGALP00010043768.1" } ] } }, { "isoform_ac": "A0A8V1ANI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09/entry#A0A8V1ANI7-1", "sequence": { "sequence": "MTVKAVKMPCTTPNVYTKVPDGGWGWAIAVAFFFVEALTYGVIKSFGVFFNDLMESFDETNSRISWIISICVFVQTFTGLGYCLSFLPTVTILSQYFDKRRSLVTAVASTGECFAVFLFAPVNTHLKEQIGWRYSLLFVGALQLSIVICGSLLRPMIIKEQEEEEEVKVQPPEEPAETKYMLENEQTRTSIESIDSGVEITTSPKNVPGNTKAEPKSEEPKDHVQITVENNSTPTEPKTKLLDFSVMRDYSFICYAFFGLFATLGFFAPSLYVIPLSRSLGISKDHSAYILSAMAIAEVLGRISAGWVLNREPIRKIHIELICVILLSVALFAFPFASEFWGLMTCSIFFGFMLGTVAGTHIPLLAEDDVVGIARMSSAAGVYVFIQSFSGLAGPPLAGVIVDRTQNYSSAFYSCAAGTVMGAVFLSLVRPCKVGMCHQQPAGAEGSVVEGTQDSPEDFIDMDIGKADHSGKGSDSVA", "length": 478, "header": "tr|A0A8V1ANI7-1|A0A8V1ANI7_CHICK Computationally mapped isoform of Solute carrier family 16 member 6 OS=Gallus gallus OX=9031 GN=SLC16A6 PE=4 SV=1 CANONICAL=A0A8V1AI09-1" }, "locus": { "chromosome": "18", "start_pos": 8436948, "end_pos": 8432638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071075.1", "url": "https://www.ensembl.org/id/ENSGALT00010071075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043766.1", "url": "https://www.ensembl.org/id/ENSGALP00010043766.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417435", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1AT66-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNSKISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQETRAEQQQTLVTAPKHSQMKAPLLDFSVLKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKGLCQNSHSGENQTDRQRGKALQDIPEDFLEMDLGKCEHRAHMKMDPV", "length": 607 }, "evidence": [ { "id": "A0A8V1AI09", "url": "https://omabrowser.org/oma/group/A0A8V1AI09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MBH6-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "SLC16A6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSHKKSQLCCRANVYTQVPDGGWGWVVAVFFFVEVFTYGIIKSFGVFFNDLMDSFNESNSRISWIISICVFVLTFTAPLSTVLSSRFGHRLVVMLGGLLVSAGMVTAAFSQKVYHMYIAIGIVSGLGFCFSFLPTVTILSQYFDRRRSVVTAVASTGECFAMFAFAPAITALKETVGWRYSMLFVGLLQLNLVVCGALLRPIVIVGAPGTPKTPAPEHRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPGHPAMVEPAAELQARGQPGAPLLDFSVLTERSFICYTLFGLFVTLGFFAPSLYIIPLGLSLGLDRDRAALLLCAMAVAEVFGRIGAGLVLNREPIRKVYIELICVILLTLSLFTFTFAAGFWGLMACSVFSGAMIGTVAGTHIPLLAEDDVVGIQKMSSAAGVYVFFQSISGLAGPPLAGLLVDQSRIYSRAFYSCAAGMLVAAVCLALVRPCKQGLCCRPRAREGKAGGPRGKKVLQDIPEDFLEMDLGKTEHRAPARTEPV", "length": 515 }, "evidence": [ { "id": "A0A8V1AI09", "url": "https://omabrowser.org/oma/group/A0A8V1AI09/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RV21-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "SLC16A6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTQKKSQLCSRANVYTQVPDGGWGWVVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNSRISWIISICVFVLTFTAPLSTVLSTRFGHRLVVMAGGLLVSTGMVTASFSQKVYHMYLAIGIISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAMFAFAPAITALKETIGWRYSLLFVGLLQLNIIVCGAMLRPIVISGPGTPKATTHENRREVQYMLENEKTRTSIDSIDSGVELTTSPRNVPSHPGVEPEPKADLQQILGKPSSKQSDQKPPLLDFSVLREKSFICYAFFGLFVTLGFFAPSLYIIPLGLSLGIDQDRSAFLLSTMAIAEVFGRIGAGLVLNREPIRKIYIELVCVILLTVSLFAFTFATDFWGLMSCSIFFGAMVGTVGGTHIPLLAEDDVVGIEKMSSAAGVYVFFQSVAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMFLAALCLALVRPCKRGLCQRPRAHEGTAETHRGKALQDIPEDFLEMDLGKHEHKGHLKTEPV", "length": 523 }, "evidence": [ { "id": "A0A8V1AI09", "url": "https://omabrowser.org/oma/group/A0A8V1AI09/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15403-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "SLC16A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLEMDLAKNEHRVHVQMEPV", "length": 523 }, "evidence": [ { "id": "A0A8V1AI09", "url": "https://omabrowser.org/oma/group/A0A8V1AI09/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08777-1", "protein_name": "Riboflavin transporter MCH5", "gene_name": "MCH5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTADYQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF", "length": 521 }, "evidence": [ { "id": "A0A8V1AI09", "url": "https://omabrowser.org/oma/group/A0A8V1AI09/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AI09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI09" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948813.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948813" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ88" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101748229", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ88", "locus": {} } ], "crossref": [ { "id": "cd14694", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14694", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101748229", "url": "https://www.ncbi.nlm.nih.gov/gene/101748229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": 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"ENSGALT00010069157.1", "url": "https://www.ensembl.org/id/ENSGALT00010069157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042599.1", "url": "https://www.ensembl.org/id/ENSGALP00010042599.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101748229", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748229", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ88" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ88" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ88" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ88" } ], "pmid": "" }, { "name": "circadian rhythm", "id": "GO:0007623", "url": 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419950" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXP3", "url": "https://www.uniprot.org/uniprotkb/E1BXP3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOL10", "url": "https://www.uniprot.org/uniprotkb/E1BXP3", "locus": { "chromosome": "3", "start_pos": 96551128, "end_pos": 96596893, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003525", "url": "https://www.ensembl.org/id/ENSGALG00010003525" } ] } } ], "crossref": [ { "id": "E1BXP3", "url": "https://alphafold.ebi.ac.uk/entry/E1BXP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016445", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016445", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421938", "url": "https://www.ncbi.nlm.nih.gov/gene/421938", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056551", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056551", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421938", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421938", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYFMDVR", "url": "https://omabrowser.org/oma/group/GYFMDVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X9V8", "url": "https://www.orthodb.org/?gene=A0A8V0X9V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXP3", "url": "https://www.orthodb.org/?gene=E1BXP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14927", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14927", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14927:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14927:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419950", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X9V8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X9V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXP3", "url": "https://www.uniprot.org/uniprotkb/E1BXP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXP3-1", "url": "https://www.uniprot.org/uniprotkb/E1BXP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVSSLNEVKIYSLSAGRSLPEWLSDRKKRALQKKDVDIRRRIELIQDFEMPTVSTKIKVSRDGQYIMAVGTYKPRIRCYDTYQLSQKFERCLDSEVVTFEILSDDYSKIVFLQCDRYVEFHSQHGHYYRTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRFLNSLPTDASENNVCDINPVHYLFATGTAEGKVECWDPRTRNRVGLLDCALSSVTADTEVDCLPSISALKFDGALNMAVGTSTGQVLLYDLRSSNPLIVKDHQYGLPIKSIQFQHQLDLIISADSRIIKMWNKDTGKIFTSMEPEYDINDVCLYPNSGMLMTANEAPRMNIYYMPVLGPAPKWCSFLDNLTEELEENPESTVYDDYKFVTRKDLENLGLAHLIGSSLLRAYMHGFFMDIRLYHKAKMMANPFAYEEYRREKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEGEEQQATRKRKQKNLPSLLKDDRFKVMFENPDFQVDEQSEEFRLLNPLVSKISEKRKKKLKLLQEQEAREQEEEEEPEGKPSDAESSESSDDEKGWVEEVRKQRKLLRQEEKVKRQERFKEDQQTLLKPQFFEIKEGEEFRSFKDSAKKQKLMKKTLGDRLKLEEKLGTLNVSDTTVGSKQATFKLKKSEHQKKQQEAEKQHRQERKALRRSASHLKSKHGRGQRFH", "length": 688, "header": "tr|E1BXP3-1|E1BXP3_CHICK Isoform 1 of Nucleolar protein 10 OS=Gallus gallus OX=9031 GN=NOL10 PE=1 SV=1 CANONICAL=E1BXP3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X9V8-1", "url": "https://www.uniprot.org/uniprotkb/E1BXP3/entry#A0A8V0X9V8-1", "sequence": { "sequence": "MQVSSLNEVKIYSLSAGRSLPEWLSDRKKRALQKKDVDIRRRIELIQDFEMPTVSTKIKVSRDGQYIMAVVVTFEILSDDYSKIVFLQCDRYVEFHSQHGHYYRTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRFLNSLPTDASENNVCDINPVHYLFATGTAEGKVECWDPRTRNRVGLLDCALSSVTADTEVDCLPSISALKFDGALNMAVGTSTGQVLLYDLRSSNPLIVKDHQYGLPIKSIQFQHQLDLIISADSRIIKMWNKDTGKIFTSMEPEYDINDVCLYPNSGMLMTANEAPRMNIYYMPVLGPAPKWCSFLDNLTEELEENPESTVYDDYKFVTRKDLENLGLAHLIGSSLLRAYMHGFFMDIRLYHKAKMMANPFAYEEYRREKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEGEEQQATRKRKQKNLPSLLKDDRFKVMFENPDFQVDEQSEEFRLLNPLVSKISEKRKKKLKLLQEQEAREQEEEEEPEGKPSDAESSESSDDEKGWVEEVRKQRKLLRQEEKVKRQERFKEDQQTLLKPQFFEIKEGEEFRSFKDSAKKQKLMKKTLGDRLKLEEKLGTLNVSDTTVGSKQATFKLKKSEHQKKQQEAEKQHRQERKALRRSASHLKSKHGRGQRFH", "length": 662, "header": "tr|A0A8V0X9V8-1|E1BXP3_CHICK Computationally mapped isoform of Nucleolar protein 10 OS=Gallus gallus OX=9031 GN=NOL10 PE=1 SV=1 CANONICAL=E1BXP3-1" }, "locus": { "chromosome": "3", "start_pos": 96596874, "end_pos": 96552293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008239.1", "url": "https://www.ensembl.org/id/ENSGALT00010008239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004894.1", "url": "https://www.ensembl.org/id/ENSGALP00010004894.1" } ] } }, { "isoform_ac": "E1BXP3-1", "url": "https://www.uniprot.org/uniprotkb/E1BXP3/entry#E1BXP3-1", "sequence": { "sequence": "MQVSSLNEVKIYSLSAGRSLPEWLSDRKKRALQKKDVDIRRRIELIQDFEMPTVSTKIKVSRDGQYIMAVGTYKPRIRCYDTYQLSQKFERCLDSEVVTFEILSDDYSKIVFLQCDRYVEFHSQHGHYYRTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRFLNSLPTDASENNVCDINPVHYLFATGTAEGKVECWDPRTRNRVGLLDCALSSVTADTEVDCLPSISALKFDGALNMAVGTSTGQVLLYDLRSSNPLIVKDHQYGLPIKSIQFQHQLDLIISADSRIIKMWNKDTGKIFTSMEPEYDINDVCLYPNSGMLMTANEAPRMNIYYMPVLGPAPKWCSFLDNLTEELEENPESTVYDDYKFVTRKDLENLGLAHLIGSSLLRAYMHGFFMDIRLYHKAKMMANPFAYEEYRREKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEGEEQQATRKRKQKNLPSLLKDDRFKVMFENPDFQVDEQSEEFRLLNPLVSKISEKRKKKLKLLQEQEAREQEEEEEPEGKPSDAESSESSDDEKGWVEEVRKQRKLLRQEEKVKRQERFKEDQQTLLKPQFFEIKEGEEFRSFKDSAKKQKLMKKTLGDRLKLEEKLGTLNVSDTTVGSKQATFKLKKSEHQKKQQEAEKQHRQERKALRRSASHLKSKHGRGQRFH", "length": 688, "header": "tr|E1BXP3-1|E1BXP3_CHICK Isoform 1 of Nucleolar protein 10 OS=Gallus gallus OX=9031 GN=NOL10 PE=1 SV=1 CANONICAL=E1BXP3-1" }, "locus": { "chromosome": "3", "start_pos": 96596874, "end_pos": 96552293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008233.1", "url": "https://www.ensembl.org/id/ENSGALT00010008233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004892.1", "url": "https://www.ensembl.org/id/ENSGALP00010004892.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421938", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421938", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BKR4-1", "protein_name": "Nucleolar protein 10", "gene_name": "NOL10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFETLSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENNVCDINSVHGLFATGTIEGRVECWDPRTRGRVGVLDCALSSVTADSEINSLPTISALKFNGALTMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIIKMWNKNSGKIFTSLEPEHDLNDVCLYPSSGMLLTANEAPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMLNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELHGKEEEEEPEGKPSDAESSESSDDEKDWVAEVRKQRRLLQQEEKVKRQEQLREDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKLEAKNGTLSVSDTTVGSKQLTFTLKKSEQQKKQQEAEKLHRQERKAVRRSAGHLRSRPRRGRPFH", "length": 688 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HB02-1", "protein_name": "Nucleolar protein 10", "gene_name": "Nol10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENNVCDINAVHGLFATGTIEGRVECWDPRVRKRVGVLDCALNSVTADSEINSLPTISALKFNGALTMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLVLSSDSRIVKMWNRNSGKIFTSLEPEHDLNDVCLYPNSGMLLTANEAPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKATLKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSRISEKRKKQLRLLEQQELQAKNEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEERAQRRREQLEEDQETVLKPQFYEIKAGEEFRSFKESATKQRLMNKTLEDRLKLEAKHGTLNVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKKLRRSAGHLRSRPRRGRPFH", "length": 690 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P48234-1", "protein_name": "Ribosome biogenesis protein ENP2", "gene_name": "ENP2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVLKSTSANDVSVYQVSGTNVSRSLPDWIAKKRKRQLKNDLEYQNRVELIQDFEFSEASNKIKVSRDGQYCMATGTYKPQIHVYDFANLSLKFDRHTDAENVDFTILSDDWTKSVHLQNDRSIQFQNKGGLHYTTRIPKFGRSLVYNKVNCDLYVGASGNELYRLNLEKGRFLNPFKLDTEGVNHVSINEVNGLLAAGTETNVVEFWDPRSRSRVSKLYLENNIDNRPFQVTTTSFRNDGLTFACGTSNGYSYIYDLRTSEPSIIKDQGYGFDIKKIIWLDNVGTENKIVTCDKRIAKIWDRLDGKAYASMEPSVDINDIEHVPGTGMFFTANESIPMHTYYIPSLGPSPRWCSFLDSITEELEEKPSDTVYSNYRFITRDDVKKLNLTHLVGSRVLRAYMHGFFINTELYDKVSLIANPDAYKDEREREIRRRIEKERESRIRSSGAVQKPKIKVNKTLVDKLSQKRGDKVAGKVLTDDRFKEMFEDEEFQVDEDDYDFKQLNPVKSIKETEEGAAKRIRALTAAEESDEERIAMKDGRGHYDYEDEESDEEESDDETNQKSNKEELSEKDLRKMEKQKALIERRKKEKEQSERFMNEMKAGTSTSTQRDESAHVTFGEQVGELLEVENGKKSNESILRRNQRGEAELTFIPQRKSKKDGNYKSRRHDNSSDEEGIDENGNKKDNGRSKPRFENRRRASKNAFRGM", "length": 707 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54D60-1", "protein_name": "NUC153 domain-containing protein", "gene_name": "nol10", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLLTTNGVKIYNVSAGKSLPEWLSENKREELRKNKEFNQRIELIQDFSFETSSQRVRISQDGQYIMATGIYPPQFKVFELSQLSQKVSRNLDCNVVTFEMLSDDYSKPVFLRDDRYIEFHAKFGSYFKTRIPKLGRDMTYHKPSCDLYITASDTEVYRLNLEEGRFLAPLTTHLNGGINVIAQNPVHQLMMLGGENGFIECWDPRVRTMVSTINAAAALPDYNSADEDSEPISITAGKFGPDGLLLGLGTSNGGVLMYDIRSASPSMIKMHQYQLPINSINFHISGDGTQRIMSSDAKIFKSFEKDTGKIHMVLEPKNPITDVVVTNGSGLLLMPGNTQKIQTYYVPALGAAPRWCSFLDNLTEELEEDKQLVYEDYKFITRDEVAKLDIENLIGTGYLKAYMHGYFIHIKLYNKVVMSKNPTNYEDLRKQQIKDKLAEKNQTRISLTKKPTSSSSTTINKPAVNAKLAERLAAQYEIQKQDSHKPMDAEITQSSSSDPRFKAMFENRDFEQDEGSEAFLRVNPRSKISKLDKHIQDNFDKVDFDDEDSDDDNDDDDDDQDNYKNKNRNSDSEDSDDDDDYDEDDIKIKSNPITNKRKELQKEQIKSKKPIKMYEIKTGHSLPSLNGKESGKQQILKSAPFSVRVGKEIKKATGLDDKDEKDGTKITKKDNGDLEIAFIPSASKKNLNNKSKKVVKKK", "length": 699 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RJG1-1", "protein_name": "Nucleolar protein 10", "gene_name": "Nol10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKNVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENNVCDINAVHGLFATGTIEGRVECWDPRVRKRVGVLDCALNSVTADSEINSLPTISALKFNGALSMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLVLSADSRIVKMWNKDSGKIFTSLEPEHDLNDVCLYPSSGMLLTANESPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTLKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSRISEKRKKQLRLLEQQELKDEEEEEPEGKPSDAESSESSDDEKGWVEEVRKQRRLLQQEERVKRQEQLKEDQQTVLKPQFYEIKAGEEFRSFKESATKQRLMNKTLEDRLKLEAKHGTLNVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKNLRRSASHLRSRPRRGRPFH", "length": 687 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66H99-1", "protein_name": "Nucleolar protein 10", "gene_name": "Nol10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENNVCDINTVHGLFATGTIEGRVECWDPRVRKRVGVLDCALNSVTADSEINSLPTISALKFNGALSMAVGTSTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLVLSADSRIVKMWNKDSGKIFTSLEPEHDLNDVCLYPSSGMILTANESPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTLKKKVKSLPNILTDDRFKVMFENPDFQVDEDSEEFRLLNPLVSRISEKRKKQLRLLEQQEQLKNEEEEEPEGKPSDAESSESSDDEKDWVEEVRKQRRLLQQEERVKRQEQLKEDQQTVLKPQFYEIKAGEEFRSFKESATKQKLMNKTLEDRLKLEAKHGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKKLRRSASHLRSRPRRGRPFH", "length": 688 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BSC4-1", "protein_name": "Nucleolar protein 10", "gene_name": "NOL10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDGQYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFYYKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENNVCDINSVHGLFATGTIEGRVECWDPRTRNRVGLLDCALNSVTADSEINSLPTISALKFNGALTMAVGTTTGQVLLYDLRSDKPLLVKDHQYGLPIKSVHFQDSLDLILSADSRIVKMWNKNSGKIFTSLEPEHDLNDVCLYPNSGMLLTANETPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENLGLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPKVNKELALKLIEEEEEKQKSTWKKKVKSLPNILTDDRFKVMFENPDFQVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAESSESSDDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQKLMNKTLEDRLKIEAKNGTLSVSDTTVGSKQLTFTLKRSEQQKKQQEAEKLHRQERKRLRRSAGHLKSRHKRGRSFH", "length": 688 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M1J9-1", "protein_name": "Embryo sac development arrest 7", "gene_name": "EDA7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTSYGDRLKSTSINGVKLYNVSSAPNVPTWLNPKKQRALRKNPHYMQRVELIQELKFETATTRIKATPDGEYLIASGIYPPQVKVYELNQLALKFERHLDSEIVDFEILDDDFSKLAFLCADRSINLHAKYGKHHTLRIPRMGRDMTYDSWSCDLLCAASSPDLYRINLEQGRFLSPLSTQSPALNVVSRSNLHGLVACGGEDGAVEFFDMRMKSSAARINAVTHGGDAAAEVTAIEFDDSEGLQVAVGSSAGKVFIYDLRTSTPIRVKDHMYESPILNIKWQRTLNTQQPKLITTDKHIVRIWDPNTGEGMTSIEPTQGGINDICVFRGSGLMLLALDSSLIPSYFIPELGPAPKWCSPLENLTEELEESAQTTIYDNYKFLAMEDLEKLQLTHLIGTDLLKASMHGYFINYHLYKKALAVIEPFAFDDYLERRKQEKLEEQRTQRITKKRRLPKVNRDLAARLHGDESEEENKTAEDGEATKKVLKKKKPILTDEHFVDGRFGSMFQNPDFQIDKDSYEYGVLHPVASSKKQPSLLDEHFEAVSDDDENSDSDASQPSDDEADDGDATRPSKKARTPKLYEVKDERHAAAYHNRTSLAKEDSLPMGERVKAIENRRGNFGGSKDIKFGPGGSREFSFKARGSSKYKEDRDDEYEDGQRNKRRGVQSLGLKSTNIRGGFRGRGGGGFRGRGGGGSRGKGGRGGGRGRGRQ", "length": 711 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V3P2-1", "protein_name": "Nucleolar protein 10", "gene_name": "l(2)34Fd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFVNEVNDVKIYNLSAGKSVPDWLTDRRKRSQLMKKVDSRRQIELIQDFDMPGVCTSIRMSPDQQYILATGTYKPRVKCFEVSNLSIKFERCFDAEVTTFEVISDDYSKMVFLQCDRYVEIHAAHGRHYRLRIPRFGRDMKYHKPSCDMFIVGVGRDIFRLNLERGQFLQPFETDGSCLNACEVNPEHHLLVAGTKEGTVEAWDPRTKQRCSTLDVAMKLPGVKEFPSVTALKFRNGLHMGVGTASGHVLIYDIRAKQPLLVKNHLNRLPIKRLAFNPAQNAVYSLDEATLKLWDEQTGKQIAYVESTSSFNDFCTIPDTGMFFVAQEDVKMMTYYVPAMGPAPRWCSFLDNLTEEIESEVVENVYDDYQFVTAKELAELGMEHLVGSNLLKGYMHGYFMDARLYNKAKAVVEPFAFDRFRKDKIRQEIESERKSRLQIESKLPKVNKELALKIMDEQANPSNSAKQRNVPSLLEDSRFKAMFENADFEVNKSAEEYRLLAPVLNRLDKSKAKELKKRVEVAHVAELHADEAQQREESDNDEDLFGFEKSDGETKDDSGDEASSDDDDRREYVKEMKQAYKQVKRQREEEEELEDDEQQPDEISDTAKRPQTNGHSQQPTTNGNRFTMTPLDQHQGSSLLQQRIKKASLQDRVRVMSQLEGQVTNVGRSLGNRQMTFEVNKQKKSQFHAKKREAEMKKHREERRSIVRPIKSLRLKKVNFK", "length": 721 }, "evidence": [ { "id": "E1BXP3", "url": "https://omabrowser.org/oma/group/E1BXP3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BXP3", "url": "https://www.uniprot.org/uniprotkb/E1BXP3" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "E1BXP3", "url": "https://www.uniprot.org/uniprotkb/E1BXP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "E1BXP3", "url": "https://www.uniprot.org/uniprotkb/E1BXP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BXP3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 688, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BXP3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BXP3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BXP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXP3" }, { "id": "PF08159", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NUC153", "eco_id": "ECO_0000259", "start_pos": 482, "end_pos": 508, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BXP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXP3" }, { "id": "PF23098", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23098" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 10-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 364, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BXP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXP3" }, { "id": "PF23097", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 10-like second", "eco_id": "ECO_0000259", "start_pos": 369, "end_pos": 417, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 356, "end_pos": 358 }, { "start_pos": 632, "end_pos": 634 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTK3-1", "uniprot_ac": "E1BTK3", "uniprot_id": "E1BTK3_CHICK", "mass": { "chemical_mass": 24475.0, "monoisotopic_mass": 24475.0 }, "refseq": { "ac": "NP_001264287", "name": "zinc finger CCHC-type and RNA-binding motif-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264287" }, "gene_names": [ { "name": "ZCRB1", "type": "recommended", "evidence": [ { "id": "E1BTK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTK3" } ] }, { "name": "ZCRB1", "type": "synonym", "evidence": [ { "id": "NP_001264287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264287" } ] } ], "protein_names": [ { "name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "type": "recommended", "evidence": [ { "id": "E1BTK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTK3/entry#names_and_taxonomy" } ] }, { "name": "U11/U12 small nuclear ribonucleoprotein 31 kDa protein", "type": "synonym", "evidence": [ { "id": "E1BTK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTK3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCHC-type and RNA binding motif 1", "type": "synonym", "evidence": [ { "id": "NP_001264287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264287" } ] }, { "name": "zinc finger CCHC-type and RNA-binding motif-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001264287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264287" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01003073.1, HAEK01117661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992453 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Apr 5, 2013 this sequence version replaced XP_416034.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264287" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTK3", "url": "https://www.uniprot.org/uniprotkb/E1BTK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZCRB1", "url": "https://www.uniprot.org/uniprotkb/E1BTK3", "locus": { "chromosome": "1", "start_pos": 29708126, "end_pos": 29718549, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001834", "url": "https://www.ensembl.org/id/ENSGALG00010001834" } ] } } ], "crossref": [ { "id": "E1BTK3", "url": "https://alphafold.ebi.ac.uk/entry/E1BTK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009544", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009544", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417791", "url": "https://www.ncbi.nlm.nih.gov/gene/417791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417791", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHYFNDE", "url": "https://omabrowser.org/oma/group/AHYFNDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XAA9", "url": "https://www.orthodb.org/?gene=A0A8V0XAA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTK3", "url": "https://www.orthodb.org/?gene=E1BTK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46259", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46259", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46259:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46259:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XAA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XAA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTK3", "url": "https://www.uniprot.org/uniprotkb/E1BTK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTK3-1", "url": "https://www.uniprot.org/uniprotkb/E1BTK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFALTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKESAQNCSRALNNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGEAGHLSYACPKNMLGEREPPKKKEKKKRKKVVEPEEIEEEEESEEEGEDPALDSLSQAIAVQQAKIEEEQQRWTQTAGESSVSDDSKRPRIKKSAYFSDEEELSD", "length": 216, "header": "tr|E1BTK3-1|E1BTK3_CHICK Isoform 1 of Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Gallus gallus OX=9031 GN=ZCRB1 PE=4 SV=1 CANONICAL=E1BTK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XAA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTK3/entry#A0A8V0XAA9-1", "sequence": { "sequence": "MGLLLNPMEIMYWLPADALKKMSGGLAPSKSTVYVSNLPFALTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKESAQNCSRALNNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGEAGHLSYACPKNMLGEREPPKKKEKKKRKKVVEPEEIEEEEESEEEGEDPALDSLSQAIAVQQAKIEEEQQRWTQTAGESSVSDDSKRPRIKKSAYFSDEEELSD", "length": 237, "header": "tr|A0A8V0XAA9-1|E1BTK3_CHICK Computationally mapped isoform of Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Gallus gallus OX=9031 GN=ZCRB1 PE=4 SV=1 CANONICAL=E1BTK3-1" }, "locus": { "chromosome": "1", "start_pos": 29718367, "end_pos": 29708671, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004176.1", "url": "https://www.ensembl.org/id/ENSGALT00010004176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002473.1", "url": "https://www.ensembl.org/id/ENSGALP00010002473.1" } ] } }, { "isoform_ac": "E1BTK3-1", "url": "https://www.uniprot.org/uniprotkb/E1BTK3/entry#E1BTK3-1", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFALTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKESAQNCSRALNNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGEAGHLSYACPKNMLGEREPPKKKEKKKRKKVVEPEEIEEEEESEEEGEDPALDSLSQAIAVQQAKIEEEQQRWTQTAGESSVSDDSKRPRIKKSAYFSDEEELSD", "length": 216, "header": "tr|E1BTK3-1|E1BTK3_CHICK Isoform 1 of Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Gallus gallus OX=9031 GN=ZCRB1 PE=4 SV=1 CANONICAL=E1BTK3-1" }, "locus": { "chromosome": "1", "start_pos": 29714765, "end_pos": 29708671, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004175.1", "url": "https://www.ensembl.org/id/ENSGALT00010004175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002472.1", "url": "https://www.ensembl.org/id/ENSGALP00010002472.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417791", "resource": "KEGG Pathway" }, { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TVT7-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKIPEPEEEIEEVEESDDEGEDPALDSLSQAIAFQQAKIEEEQRKWKPSSGGPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "E1BTK3", "url": "https://omabrowser.org/oma/group/E1BTK3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2N728-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "Zcrb1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRRSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKVPEPEEVEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQNKWRPSPGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 216 }, "evidence": [ { "id": "E1BTK3", "url": "https://omabrowser.org/oma/group/E1BTK3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q499V6-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "Zcrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKVPEPEEEIEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQNKWRPSTGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "E1BTK3", "url": "https://omabrowser.org/oma/group/E1BTK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q56JZ7-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRRSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKIPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGGPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "E1BTK3", "url": "https://omabrowser.org/oma/group/E1BTK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5SP50-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "zcrb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGGLAPSKSTVYVSNIPFSLTNSDMHKLCSKYGKVVKVTIVKDKHTRMSKGVAFVLFLDRESAYNCSRSLNNKQLFGRMVKASIAIDNGRAAEFIRKRNYTDKSKCYECGEEGHLSYACPKNLLGEREPPPKKEKKKKKKVQQPEEVEPEDSEEEGEDPALDSLSQAIAFQQARIEEEEKRRKQAAEDASQASTSEDTHKPRIKKSAYFSDEEELSD", "length": 218 }, "evidence": [ { "id": "E1BTK3", "url": "https://omabrowser.org/oma/group/E1BTK3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8TBF4-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "ZCRB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSAQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKKKAPEPEEEIEEVEESEDEGEDPALDSLSQAIAFQQAKIEEEQKKWKPSSGVPSTSDDSRRPRIKKSTYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "E1BTK3", "url": "https://omabrowser.org/oma/group/E1BTK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZ96-1", "protein_name": "Zinc finger CCHC-type and RNA-binding motif-containing protein 1", "gene_name": "Zcrb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGGLAPSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDSALNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGEREPPKKKEKKKKRKLPEPEEEIEEVEVSEEEGEDPALDSLSQAIAFQQAKIEEEQSKWRPNPGGPSTSDDSRRPRIKKSAYFSDEEELSD", "length": 217 }, "evidence": [ { "id": "E1BTK3", "url": "https://omabrowser.org/oma/group/E1BTK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BTK3", "url": "https://www.uniprot.org/uniprotkb/E1BTK3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BTK3", "url": "https://www.uniprot.org/uniprotkb/E1BTK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "E1BTK3", "url": "https://www.uniprot.org/uniprotkb/E1BTK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "E1BTK3", "url": "https://www.uniprot.org/uniprotkb/E1BTK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK73", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK77", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSRGAPRALLSFVCRRGRATRWGRARGCAWHRAGVGGGVRNPQQPAVAQETRACAQPRSAHGEGATRFPPPRNIRAHPSRAGGGGMNGGRAGGCPSSPPPLLSPSPPPIPPAGVPQRGAERGGAGPGAGPGAGTGRTMRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1901, "header": "tr|A0A8V1ALZ8-1|A0A8V1ALZ8_CHICK Isoform 1 of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1AAK4-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1745, "header": "tr|A0A8V1AAK4-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069883.1", "url": "https://www.ensembl.org/id/ENSGALT00010069883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043009.1", "url": "https://www.ensembl.org/id/ENSGALP00010043009.1" } ] } }, { "isoform_ac": "A0A8V1AAK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1AAK9-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1709, "header": "tr|A0A8V1AAK9-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069888.1", "url": "https://www.ensembl.org/id/ENSGALT00010069888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043014.1", "url": "https://www.ensembl.org/id/ENSGALP00010043014.1" } ] } }, { "isoform_ac": "A0A8V1AFX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1AFX9-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1745, "header": "tr|A0A8V1AFX9-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069885.1", "url": "https://www.ensembl.org/id/ENSGALT00010069885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043011.1", "url": "https://www.ensembl.org/id/ENSGALP00010043011.1" } ] } }, { "isoform_ac": "A0A8V1AHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1AHZ7-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1736, "header": "tr|A0A8V1AHZ7-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069882.1", "url": "https://www.ensembl.org/id/ENSGALT00010069882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043008.1", "url": "https://www.ensembl.org/id/ENSGALP00010043008.1" } ] } }, { "isoform_ac": "A0A8V1AI03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1AI03-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1727, "header": "tr|A0A8V1AI03-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069887.1", "url": "https://www.ensembl.org/id/ENSGALT00010069887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043013.1", "url": "https://www.ensembl.org/id/ENSGALP00010043013.1" } ] } }, { "isoform_ac": "A0A8V1AK73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1AK73-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAVRISSPLLASGGAGNWVQELPFKAPPPLGAVLLFGCTNTALGWLMLAFPLQGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1796, "header": "tr|A0A8V1AK73-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069881.1", "url": "https://www.ensembl.org/id/ENSGALT00010069881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043007.1", "url": "https://www.ensembl.org/id/ENSGALP00010043007.1" } ] } }, { "isoform_ac": "A0A8V1AK77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1AK77-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1745, "header": "tr|A0A8V1AK77-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069886.1", "url": "https://www.ensembl.org/id/ENSGALT00010069886.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043012.1", "url": "https://www.ensembl.org/id/ENSGALP00010043012.1" } ] } }, { "isoform_ac": "A0A8V1ALZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1ALZ6-1", "sequence": { "sequence": "MRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1674, "header": "tr|A0A8V1ALZ6-1|A0A8V1ALZ8_CHICK Computationally mapped isoform of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069884.1", "url": "https://www.ensembl.org/id/ENSGALT00010069884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043010.1", "url": "https://www.ensembl.org/id/ENSGALP00010043010.1" } ] } }, { "isoform_ac": "A0A8V1ALZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8/entry#A0A8V1ALZ8-1", "sequence": { "sequence": "MQSRGAPRALLSFVCRRGRATRWGRARGCAWHRAGVGGGVRNPQQPAVAQETRACAQPRSAHGEGATRFPPPRNIRAHPSRAGGGGMNGGRAGGCPSSPPPLLSPSPPPIPPAGVPQRGAERGGAGPGAGPGAGTGRTMRCGALALALLCALPLGAAGLELPETGSGLQADEVNLLDKVTSHAQDLSNVSFSYDEANCSTLQIGQYSTLSIPTQEVFGDRFADELSVLMKLRYSLQEDTSLVTILSHRSHVLFQIRVSPHGLVFVTTRKRHYEFPVSLLSDGRWHRIALSISQESLELHVDCRLVERASWPGYLGMGVGTEGLLVIGGLVESFEIPFEGALQQLTFVMGDAAAAGEHCRSHTVTCVRSSGLSPPPRDHSAAWPEDSKLSHSDLTLGPPWTWEDAQETLSLQPDGSTRTLFSAAEVPTAEEQEEEEGSLSIEDEGFELLNSTYNKVTDPGKPGISRSRPRIIGILGPSAKKEQASDQENITTEKLKGNANTHLHLPPIKPGGATKPIASSKVSPARHQAAAPKGSSGMAAGDPEHPPTPLRNPILPSVHGYWARVKPGPPGLPGPPGLPGCPGRRGLVGPKGDKGHAGAMGRMGPPGDPGPMGIPGVPTVVLWRNSREDWLSFTQSSFYQLLHAGWPRKPGAPGPPGHPGKAGVPGLCGEPGEPGEKGQRGYTGKPGLQGWPGRAGQPGLDGSPGLGGKPGLCGLPGEQGLQGFRGDRGLAGEKGEEGFLGDPGPAGEKGEKGMKGVKGESGLPGPAGAHGMAGLKGAMGFQGPAGPEGEGGSVGASGPAGPMGQPGQPGSVGCQGVNGSQGEMGPPGLPGPHGPKGPQGLQGRRGPPGLGGMQGPAGMEGSSGPKGDAGTEGVPGMRGQPGQEGPVGFIGLPGSKGVQGERGCRGPSGAKGELGAKGDKGLHGAPGAVGPPGLRGQMGSLGFPGPRGAAGPRGPEGEEGQMGPMGLNSSEGPKGGRGPDGPKGMPGPRGARGRGGQRGLVGAPGAPGSRGIPGAEGTEGKPGIQGPPGAVGSPGRMGAPGFVGVQGGRGHTGPPGPTGPQGKPGADGDLGCMGPKGLPGKPGLEGPQGPVGMYGYPGLAGDRGKPGHRGEKGEAGARGPPGFPGKAGPKAPPGRPGPRGAPGSQGRAGEPGPRGLPGLPGAPGVRGLHGMPGKPGLAGEIGAPGAAGAAGPPGYPGREGPRGPEGPSGMRGEQGVLGDPGEAGVSGLDGEQGPPGPVGAEGRPGLKGQQGDAGPRGAPGVSGACGERGDRGPAGLPGGPGQQGKEGDVGDAGELGEPGPRGRKGDAGPQGPPGVPGLGAAPGEAGEKGRKGEKGQEGLLGQLGVSGAAGPAGARGRSGGTGLRGPPGLRGLEGVKGDAGPCGRDGAAGAAGLEGPAGEDGAKGDPGHPGPVGSVGARGRPGGPGFKGYIGHRGAGGAAGTRGQPGRQGPLGPPGNAGVPGSGGIEGVVGAKGEPGTVGEPGHTGSPGPAGPPGQKGHKGEKGDVGQEGPEGAPGEAGRRGKRGKVGHRAPRGPRGPKGHQGAEGLAGPQGLQGLYGIPGLKGFIGDPGHKGPKGEKGSRGHQGQHGDDGFKGKHGPQGTPGRPGPKGEQGDTGPPGPRGLPGLPGKPGLPGQKGLKGFLGHPGARGKPGPPGLAGPPGPSGPALMLSEEELWHLIYPADCLNRTTVLALLHTLSRELRALVEHPDGTKDKPAATCKELLLAHPNLPDGHYYIDPNQGSTRDALVAFCNFTAGGETCIPPVHNQVPIKAWLSSYASSDTFEWFSTLPGGFMLEYVGASVVQLRFLRLHSHRAAQKVSYSCRPAAHHHRQPQKEIRFLADTREQSYVATLQGCLLDNDSSIADTIFHFATEELALLPLRDLAVFHDGDASHQFGFTIGPVCFS", "length": 1901, "header": "tr|A0A8V1ALZ8-1|A0A8V1ALZ8_CHICK Isoform 1 of Fibrillar collagen NC1 domain-containing protein OS=Gallus gallus OX=9031 GN=COL1A4 PE=4 SV=1 CANONICAL=A0A8V1ALZ8-1" }, "locus": { "chromosome": "17", "start_pos": 3082285, "end_pos": 3039301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069889.1", "url": "https://www.ensembl.org/id/ENSGALT00010069889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043015.1", "url": "https://www.ensembl.org/id/ENSGALP00010043015.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1057, "start_aa": "Thr", "end_pos": 1057, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1057", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1599, "start_aa": "Thr", "end_pos": 1599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1599", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1682, "end_pos": 1684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1748, "end_pos": 1750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1855, "end_pos": 1857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 817, "end_pos": 819, "annotation": "n_glycosylation_sequon" }, { "start_pos": 967, 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Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane. Required for correct assembly and maintenance of the mitotic spindle, and proper progression of mitosis. Involved in neuron morphogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8#function" }, { "database": "UniProtKB", "id": "ARBA00057349", "url": "https://www.uniprot.org/uniprotkb/ARBA00057349#function" }, { "database": "UniProtKB", "id": "A0A8V1AK64", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK64#function" }, { "database": "UniProtKB", "id": "A0A8V1AM59", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM59#function" }, { "database": "UniProtKB", "id": "A0A8V1ACX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACX7#function" }, { "database": "UniProtKB", "id": "A0A8V1AI94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI94#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBCD", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8", "locus": { "chromosome": "18", "start_pos": 3857296, "end_pos": 3967188, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029421", "url": "https://www.ensembl.org/id/ENSGALG00010029421" } ] } } ], "crossref": [ { "id": "A0A8V1ANP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "417334", "url": "https://www.ncbi.nlm.nih.gov/gene/417334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM59", "url": "https://www.orthodb.org/?gene=A0A8V1AM59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANP8", "url": "https://www.orthodb.org/?gene=A0A8V1ANP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12658:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12658:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23579", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23579", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25767", 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"MAVGETDGAGSEESGSREADVISRGNILESFTESQEVRALLGNLRTVYGDPVAQEVIVEKFIVIMDKYQEQPHLLDRHLEWMMNMLLDIIRDSGSPPVLFHLAFKFLYIITKVRGYKLFLRLFPHEVTDLQPVLDMIVDQNPKDCETWETRYMLLLWLSMICLIPFDLARFDGNILSEEGHTRMPTMDRILEIAKCYLVVSDKARDAAAVLVSKFIVRPDVRQKRMADFLDWTLSMLSKSSFQSMEGTVVMNGMLQALAQLFKHGKREDCLPYAATVLECLDNCKLSESNQMVLRKLGMKLVQRLGLTFVKPKVAKWRYQRGCRSLAANLQAQSSVMQSQKITVAANEAEDDEEYDIPGEIENVVEQLLVGLKDKDTIVRWSAAKGIGRITGRLPKELADDVVGSLLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRISDGGLHEVHACCLCVPLINLTRICKVMLLLYLEVVPVILKALTYDEKRGSCSVGSNVRDAACYLSWAFARAYDPSELIPFINQISSALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTAADYFAVGNRVNCYLTISVYIAGFPEYTQPMIDHLVNMKINHWDSVIRELSTKALHNLTPRAPEYMANVVLPRLLPLSVGTDLHTRHGAILACAEITHALCKLAEENNRSITYYFNGKSLEGLKQIHQELCSRQLYRGLGGELMRPAVCTLIEKLSLSKMPFKGDPIIEGWQWLINDSLRSLPLASCAARQHVKESAVSALSALCNEYYINENGEADPALQGELVTQYISELQSTEQMIRCGFSLALGALPRFLLKGRLQQVLEGLRKVTLITPRDVSFAESRRDALIAIAEICQTVGVKGEGSQEEYICKDNVAQIYATLLNCVTDYTTDSRGDVGGWVREAAMTSLMKVTLLLVQNEAELINANICKQIMCWLAQQSAEKIDKFRAHAGSVFLTLLHFDSPPVPHIPHREELERIFPRSEAETLNWNAASEAFPRITQLLALPAYQYYVLLGLSVSVGGLTETTLRYSAQSLFDYMKNIQNDSSAMEGFCETLLKVFEDNLRNDRVSVPLLTMLDQMLANGCFDIFTTQGNHPFPVKLLHLCKEEIKRSKDVRKLRSSIGVFCGLIQFQGDMREKVLFQLLLLLCHPFPVIRKTTASQVYEMLITYSEIIDPAIVDEVMAILSDSNWEAEVAELREKRNRLCDLMKVPKPQLVTKSSAK", "length": 1227, "header": "tr|A0A8V1ACX7-1|A0A8V1ANP8_CHICK Computationally mapped isoform of Tubulin-specific chaperone D OS=Gallus gallus OX=9031 GN=TBCD PE=1 SV=1 CANONICAL=A0A8V1ANP8-1" }, "locus": { "chromosome": "18", "start_pos": 3966958, "end_pos": 3858326, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071173.1", "url": "https://www.ensembl.org/id/ENSGALT00010071173.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043864.1", "url": "https://www.ensembl.org/id/ENSGALP00010043864.1" } ] } }, { "isoform_ac": "A0A8V1AI94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8/entry#A0A8V1AI94-1", "sequence": { "sequence": "MAVGETDGAGSEESGSREADVISRGNILESFTESQEVRALLGNLRTVYGDPVAQEVIVEKFIVIMDKYQEQPHLLDRHLEWMMNMLLDIIRDSGSPPVLFHLAFKFLYIITKVRGYKLFLRLFPHEVTDLQPVLDMIVDQNPKDCETWETRYMLLLWLSMICLIPFDLARFDGNILSEEGHTRMPTMDRILEIAKCYLVVSDKARDAAAVLVSKFIVRPDVRQKRMADFLDWTLSMLSKSSFQSMEGTVVMNGMLQALAQLFKHGKREDCLPYAATVLECLDNCKLSESNQMVLRKLGMKLVQRLGLTFVKPKVAKWRYQRGCRSLAANLQAQSSVMQSQKITVAANEAEDDEEYDIPGEIENVVEQLLVGLKDKDTIVRWSAAKGIGRITGRLPKELADDVVGSLLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRISDVVPVILKALTYDEKRGSCSVGSNVRDAACYLSWAFARAYDPSELIPFINQISSALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTAADYFAVGNRVNCYLTISVYIAGFPEYTQPMIDHLVNMKINHWDSVIRELSTKALHNLTPRAPEYMANVVLPRLLPLSVGTDLHTRHGAILACAEITHALCKLAEENNRSITYYFNGKSLEGLKQIHQEVCSKGLGGELMRPAVCTLIEKLSLSKMPFKGDPIIEGWQWLINDSLRSLPLASCAARQHVKESAVSALSALCNEYYINENGEADPALQGELVTQYISELQSTEQMIRCGFSLALGALPRFLLKGRLQQVLEGLRKVTLITPRDVSFAESRRDALIAIAEICQTVGVKGEGSQEEYICKDNVAQIYATLLNCVTDYTTDSRGDVGGWVREAAMTSLMKVTLLLVQNEAELINANICKQIMCWLAQQSAEKIDKFRAHAGSVFLTLLHFDSPPVPHIPHREELERIFPRSEAETLNWNAASEAFPRITQLLALPAYQYYVLLGLSVSVGGLTETTLRYSAQSLFDYMKNIQNDSSAMEGFCETLLKVFEDNLRNDRVSVPLLTMLDQMLANGCFDIFTTQGNHPFPVKLLHLCKEEIKRSKDVRKLRSSIGVFCGLIQFQGDMREKVLFQLLLLLCHPFPVIRKTTASQVYEMLITYSEIIDPAIVDEVMAILSDSNWEAEVAELREKRNRLCDLMKVPKPQLVTKPAGTHTGAHIS", "length": 1199, "header": "tr|A0A8V1AI94-1|A0A8V1ANP8_CHICK Computationally mapped isoform of Tubulin-specific chaperone D OS=Gallus gallus OX=9031 GN=TBCD PE=1 SV=1 CANONICAL=A0A8V1ANP8-1" }, "locus": { "chromosome": "18", "start_pos": 3966958, "end_pos": 3858546, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071175.1", "url": "https://www.ensembl.org/id/ENSGALT00010071175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043866.1", "url": "https://www.ensembl.org/id/ENSGALP00010043866.1" } ] } }, { "isoform_ac": "A0A8V1AK64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8/entry#A0A8V1AK64-1", "sequence": { "sequence": "MAVGETDGAGSEESGSREADVISRGNILESFTESQEVRALLGNLRTVYGDPVAQEVIVEKFIVIMDKYQEQPHLLDRHLEWMMNMLLDIIRDSGSPPVLFHLAFKFLYIITKVRGYKLFLRLFPHEVTDLQPVLDMIVDQNPKDCETWETRYMLLLWLSMICLIPFDLARFDGNILSEEGHTRMPTMDRILEIAKCYLVVSDKARDAAAVLVSKFIVRPDVRQKRMADFLDWTLSMLSKSSFQSMEGTVVMNGMLQALAQLFKHGKREDCLPYAATVLECLDNCKLSESNQMVLRKLGMKLVQRLGLTFVKPKVAKWRYQRGCRSLAANLQAQSSVMQSQKITVAANEAEDDEEYDIPGEIENVVEQLLVGLKDKDTIVRWSAAKGIGRITGRLPKELADDVVGSLLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRISDVVPVILKALTYDEKRGSCSVGSNVRDAACYLSWAFARAYDPSELIPFINQISSALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTAADYFAVGNRVNCYLTISVYIAGFPEYTQPMIDHLVNMKINHWDSVIRELSTKALHNLTPRAPEYMANVVLPRLLPLSVGTDLHTRHGAILACAEITHALCKLAEENNRSITYYFNGKSLEGLKQIHQEVLPLRLLCRGLGGELMRPAVCTLIEKLSLSKMPFKGDPIIEGWQWLINDSLRSLPLASCAARQHVKESAVSALSALCNEYYINENGEADPALQGELVTQYISELQSTEQMIRCGFSLALGALPRFLLKGRLQQVLEGLRKVTLITPRDVSFAESRRDALIAIAEICQTVGVKGEGSQEEYICKDNVAQIYATLLNCVTDYTTDSRGDVGGWVREAAMTSLMKVTLLLVQNEAELINANICKQIMCWLAQQSAEKIDKFRAHAGSVFLTLLHFDSPPVPHIPHREELERIFPRSEAETLNWNAASEAFPRITQLLALPAYQYYVLLGLSVSVGGLTETTGVCAPPDNAGPNAGKRLF", "length": 1020, "header": "tr|A0A8V1AK64-1|A0A8V1ANP8_CHICK Computationally mapped isoform of Tubulin-specific chaperone D OS=Gallus gallus OX=9031 GN=TBCD PE=1 SV=1 CANONICAL=A0A8V1ANP8-1" }, "locus": { "chromosome": "18", "start_pos": 3966958, "end_pos": 3869614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071172.1", "url": "https://www.ensembl.org/id/ENSGALT00010071172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043863.1", "url": "https://www.ensembl.org/id/ENSGALP00010043863.1" } ] } }, { "isoform_ac": "A0A8V1AM59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8/entry#A0A8V1AM59-1", "sequence": { "sequence": "MAVGETDGAGSEESGSREADVISRGNILESFTESQEVRALLGNLRTVYGDPVAQEVIVEKFIVIMDKYQEQPHLLDRHLEWMMNMLLDIIRDSGSPPVLFHLAFKFLYIITKVRGYKLFLRLFPHEVTDLQPVLDMIVDQNPKDCETWETRYMLLLWLSMICLIPFDLARFDGNILSEEGHTRMPTMDRILEIAKCYLVVSDKARDAAAVLVSKFIVRPDVRQKRMADFLDWTLSMLSKSSFQSMEGTVVMNGMLQALAQLFKHGKREDCLPYAATVLECLDNCKLSESNQMVLRKLGMKLVQRLGLTFVKPKVAKWRYQRGCRSLAANLQAQSSVMQSQKITVAANEAEDDEEYDIPGEIENVVEQLLVGLKDKDTIVRWSAAKGIGRITGRLPKELADDVVGSLLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRISDVVPVILKALTYDEKRGSCSVGSNVRDAACYLSWAFARAYDPSELIPFINQISSALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTAADYFAVGNRVNCYLTISVYIAGFPEYTQPMIDHLVNMKINHWDSVIRELSTKALHNLTPRAPEYMANVVLPRLLPLSVGTDLHTRHGAILACAEITHALCKLAEENNRSITYYFNGKSLEGLKQIHQELCSRQLYRGLGGELMRPAVCTLIEKLSLSKMPFKGDPIIEGWQWLINDSLRSLPLASCAARQHVKESAVSALSALCNEYYINENGEADPALQGELVTQYISELQSTEQMIRCGFSLALGALPRFLLKGRLQQVLEGLRKVTLITPRDVSFAESRRDALIAIAEICQTVGVKGEGSQEEYICKDNVAQIYATLLNCVTDYTTDSRGDVGGWVREAAMTSLMKVTLLLVQNEAELINANICKQIMCWLAQQSAEKIDKFRAHAGSVFLTLLHFDSPPVPHIPHREELERIFPRSEAETLNWNAASEAFPRITQLLALPAYQYYVLLGLSVSVGGLTETTLRYSAQSLFDYMKNIQNDSSAMEGFCETLLKVFEDNLRNDRVSVPLLTMLDQMLANGCFDIFTTQGNHPFPVKLLHLCKEEIKRSKDVRKLRSSIGVFCGLIQFQGDMREKVLFQLLLLLCHPFPVIRKTTASQVYEMLITYSEIIDPAIVDEVMAILSDSNWEAEVAELREKRNRLCDLMKVPKPQLVTKPAGTHTGAHIS", "length": 1203, "header": "tr|A0A8V1AM59-1|A0A8V1ANP8_CHICK Computationally mapped isoform of Tubulin-specific chaperone D OS=Gallus gallus OX=9031 GN=TBCD PE=1 SV=1 CANONICAL=A0A8V1ANP8-1" }, "locus": { "chromosome": "18", "start_pos": 3966958, "end_pos": 3858546, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071176.1", "url": "https://www.ensembl.org/id/ENSGALT00010071176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043867.1", "url": "https://www.ensembl.org/id/ENSGALP00010043867.1" } ] } }, { "isoform_ac": "A0A8V1ANP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8/entry#A0A8V1ANP8-1", "sequence": { "sequence": "MAVGETDGAGSEESGSREADVISRGNILESFTESQEVRALLGNLRTVYGDPVAQEVIVEKFIVIMDKYQEQPHLLDRHLEWMMNMLLDIIRDSGSPPVLFHLAFKFLYIITKVRGYKLFLRLFPHEVTDLQPVLDMIVDQNPKDCETWETRYMLLLWLSMICLIPFDLARFDGNILSEEGHTRMPTMDRILEIAKCYLVVSDKARDAAAVLVSKFIVRPDVRQKRMADFLDWTLSMLSKSSFQSMEGTVVMNGMLQALAQLFKHGKREDCLPYAATVLECLDNCKLSESNQMVLRKLGMKLVQRLGLTFVKPKVAKWRYQRGCRSLAANLQAQSSVMQSQKITVAANEAEDDEEYDIPGEIENVVEQLLVGLKDKDTIVRWSAAKGIGRITGRLPKELADDVVGSLLDCFSFQETDNAWHGGCLALAELGRRGLLLPSRISDGGLHEVHACCLCVPLINLTRICKVMLLLYLEVVPVILKALTYDEKRGSCSVGSNVRDAACYLSWAFARAYDPSELIPFINQISSALVIAAVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTAADYFAVGNRVNCYLTISVYIAGFPEYTQPMIDHLVNMKINHWDSVIRELSTKALHNLTPRAPEYMANVVLPRLLPLSVGTDLHTRHGAILACAEITHALCKLAEENNRSITYYFNGKSLEGLKQIHQELCSRQLYRGLGGELMRPAVCTLIEKLSLSKMPFKGDPIIEGWQWLINDSLRSLPLASCAARQHVKESAVSALSALCNEYYINENGEADPALQGELVTQYISELQSTEQMIRCGFSLALGALPRFLLKGRLQQVLEGLRKVTLITPRDVSFAESRRDALIAIAEICQTVGVKGEGSQEEYICKDNVAQIYATLLNCVTDYTTDSRGDVGGWVREAAMTSLMKVTLLLVQNEAELINANICKQIMCWLAQQSAEKIDKFRAHAGSVFLTLLHFDSPPVPHIPHREELERIFPRSEAETLNWNAASEAFPRITQLLALPAYQYYVLLGLSVSVGGLTETTLRYSAQSLFDYMKNIQNDSSAMEGFCETLLKVFEDNLRNDRVSVPLLTMLDQMLANGCFDIFTTQGNHPFPVKLLHLCKEEIKRSKDVRKLRSSIGVFCGLIQFQGDMREKVLFQLLLLLCHPFPVIRKTTASQVYEMLITYSEIIDPAIVDEVMAILSDSNWEAEVAELREKRNRLCDLMKVPKPQLVTKPAGTHTGAHIS", "length": 1234, "header": "tr|A0A8V1ANP8-1|A0A8V1ANP8_CHICK Isoform 1 of Tubulin-specific chaperone D OS=Gallus gallus OX=9031 GN=TBCD PE=1 SV=1 CANONICAL=A0A8V1ANP8-1" }, "locus": { "chromosome": "18", "start_pos": 3966958, "end_pos": 3858546, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071174.1", "url": "https://www.ensembl.org/id/ENSGALT00010071174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043865.1", "url": "https://www.ensembl.org/id/ENSGALP00010043865.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZJB6-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "Tbcd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLSNEPAASAAEEEVEDDALVRASTLEAFGESAETRALLRSLPAVHRERAAREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDIVQDETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVADVQPVLDMFTGQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLPTQSGETRMPIMDRILQIAQSYLVVSDKARDAAAVLVSKFITRPDVKQRKMASFLDWSLCTLAHSSFQTIDGVITMDGMLQALAQIFKHGKREDCLPYANTVLQCLDGCRLPESSHTLLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLQLRAPGKSEQKLLSDSLTSDGDEDYDVPEGVETVIEQLLVGLKDKDTIVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLSEVVTVILKALTYDEKRGACSVGANVRDAACYVCWAFARAYEPQELTPFVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKINHWDGAIRELSAKALHNLTSLVPEYMATHVFPALLLMTQSPDLHTRHGAILACAEVTYALYELAAQSNRLVTDYLDEKAVQSLKQIHQQVCVSYKSLFGKIMCCFFSFSFSIVCILIEKLSLSRMPFKGDTVIEGWQWLINDTLRSLHLVSSHSREQIKHCPGLPVMRQRPLLNTSFFPEELIPQYLAELRSPEEMTRCGFSSALGALPCFLLRGHLQQVLSGLRRVTCTTSPMDVSFAEARRDGLKAISRICQTVGVNTQGPPDEVICQENISEVYAALLGCMSDYTTDSRGDVGAWVREASMTSLMDLMLLLAQTEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRKELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLGLAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLESFSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFSGDVRKKVLLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDAEVLDEVMSVLSDTAWDSELPVVRGQRNHLCDLLGVPRPQLVPKVILVVVPVLPVVLSSGLK", "length": 1208 }, "evidence": [ { "id": "A0A8V1ANP8", "url": "https://omabrowser.org/oma/group/A0A8V1ANP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BYA0-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "Tbcd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLSNEPAASAAEEEVEDDALVRASALEAFGESAETRALLRSLPAVHRERASREVAEERFRVIMDKYQEQPHLLDPHLEWMMNSLLDLVQDETSLPDLVHLAFKFLYIITKVRGYKVFLRLFPHEVANVQPVLDMFTGQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLSTQTGETRVPTMDRILQIAESYLVVSDKARDAAAVLVSKFITRPDVKQRKMASFLDWSLCTLAHSSFQTIEGVITMDGMLQALAQIFKHGKREDCLPYANTVLQCLDGCRLPESSHTSLRKLGVKLVQRLGLTFLKPKVATWRYQRGCRSLAANLKLCAPGKSDQKLLSDSLTSDGDEDYDVPEGVETVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRELADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLSEVVTVILKALTYDEKRGACSVGANVRDAACYVCWAFARAYEPQELTPFVTAISSALVIAAVFDRNVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNISNCFLIISVFIAGFQEYTKPMIDHLVSMKINHWDGAIRELSAKALHNLTPQVPEYIAMHVFPALLLMTQSPDLHTRHGAILACAEVTYALYKLATQSNRLVTDYLDEKAVQSLKQIHQQLCDRHLYRGLGGELMRQAVCILIEKLSLSRMPFKGDATVEGWQWLINDTLRSLHLVSSHSRQQIKEVAVSALTALCSEYYVKEPGEAGSSIAKELIPQYLAELQSPEEMARCGFSSALGALPGFLLRGHLQQVLSGLRRVTCISPNDVSFAEARRDGLKAISRICQTVGVNTRGPPDEVICKENISEVYAALLGCMSDYTTDSRGDVGAWVREAAMTSLMDLMLLLARTEPVLIEAHICERVMCCVAQQASEKIDRFRAHAARVFLTLLHFDSPPIPHVPHRQELESLFPRSDVATVNWNAPSQAFPLITQLLGLPTYRYHVLLGLAVSVGGLTESTVRHSTQSLFEYMKGIQKDAQVLQSFSETLLKVFEDNLLNDRVSVSLLKMLDQLLANGCFDIFTAEENHPFCVKLLTLCKEEIKKSKDIQKLRSSIAVLCGMVQFNGDVRKKILLQLFLLLGHPFPVIRKSTASQVYEMVLTYSDLVDAEVLDEVMSVLSDTAWDAELPVVREQRNRLCDLLGVPRPQLVPKPIPGS", "length": 1196 }, "evidence": [ { "id": "A0A8V1ANP8", "url": "https://omabrowser.org/oma/group/A0A8V1ANP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8L5R3-1", "protein_name": "Tubulin-folding cofactor D", "gene_name": "TFCD", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASRAEEMSPTKIEIETAVKIEEEEDDEHDSKERVLQRYFLQEWKLVKSLLDDIVSNGRVVDPTSVHKIRSIMDKYQEQGQLVEPYLESIVSPLMFIIRSKTVDLEAKPDEILEIIKPISIIIYALVTVCGYKAVIKFFPHQVSDLELAVLLLEKCHSTNSVSALRQESTGEMEAKCVTLLWLSILVLVPFDISSVDTSIADDKTFGVDDLAPLVLKILGFCKDYLCSAGPMRRISGLLLSKLLTRPDMGKAFSSFFEWTYEVLSCKEDSVTNHFRLLGVMEALSAIFKTASRKVLLDVLPIVLNDVTVLSKSNAAAKSSLLRKYLIKLTQRIGLVCLPHRSPSWRYVAQTASLSENMSTSSSQRLAPDHTVTAILQPESLDDQEDEDMDVPEILEEIIEMLLSGLRDTDTVVRWSAAKGIGRVTSRLTSVLSDEVLSSVLELFSPGEGDGSWHGGCLALAELARRGLLLPRSFPLVVPVIVKALHYDVRRGPHSVGSHVRDAAAYVCWAFGRAYSHKDMKNVLDQLAPDLLIVGSFDREVNCRRAAAAAFQENVGRQGNYPHGIDIVSIADYFSLSSRVNSYLQVAVSIAQYEGYLYPFVDELLYNKICHWDKSLRELAAEALAPLVKYEPKHFANYVLEKLIPCTLSTDLCMRHGATLAAGEVVLALHQCGYVLSADSQKRMAGIVPSIEKARLYRGKGGEIMRLAVSRFIECISLSHVTLAERTERILLDTLTENLRHPNSQIQNAAVSAVKQLVQSYLVGNDKKSVDLILKHLKHLTDPNVAVRRGSALALGVLPYELLTAKWKDIVLKLCSACKIEVNPEDRDAEARVNAVKGLTSVCETLTQKRASDPGNDDLSLFLLIKTEVMDTLLKALDDYSVDNRGDVGSWVREAAVHGLEKCTYILCKKMETYSEGDYNDDTSSLFDSNLATRLIGGMLKQGVEKMDKLRETAAKVLQRILYHKSVSVPHVPYREKLEEILPNKANLQWAVPAFSFPRFVQLLKLRCYSKEVMSGLVISIGGLQDSLRKASLVALLEYMREGEAKDPKEQQSRESALGDDILWILQEYKKCDRVMVPCLQTIEILFSSKIFLNQESYTFSFYAGVMDSLAIELRASKDFTKLKAGLAILGYIASVSHFISTKAFSQLLSFLGHRYPMIRKAAAEQVYLALLQNGILVTEEKMEKVIEIISESCWEADMETTKTQRLELCELAGLDHEVVFKTRNRLVIKDIAGNKSAADENASYSSLVDSSGF", "length": 1254 }, "evidence": [ { "id": "A0A8V1ANP8", "url": "https://omabrowser.org/oma/group/A0A8V1ANP8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9BTW9-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "TBCD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALSDEPAAGGPEEEAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERFRVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLRLFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPDVKQSKMAEFLDWSLCNLARSSFQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRCLDGCRLPESNQTLLRKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILTEDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGALPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQPGAC", "length": 1192 }, "evidence": [ { "id": "A0A8V1ANP8", "url": "https://omabrowser.org/oma/group/A0A8V1ANP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQ78-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "Tbcd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNSVEECKDEDLPANTLEHFTELQQVLEMIDNIKSIAANTFEREFEQYAQVLSRYQEQPHLLDPHLEELLGKLLHKIRKPDLDTGELHAAFKYLYIICKVRTYKVLVKFMPHELSDLEFVLDLLGQQNPKEFEQWETRYILLLWMSILVLNPFHMSRLDAYDTSTSAPTTNCSPVNHVQSKNTKMDRIFELIQLYVSSNDTCSSMAAFLAAKYFIRSDIKDLYLERFLDWIMEQHQADTLNVKFGQLAAVAAILKHGKREDLLPYADKLLQWITSCQYKDDNDFLKYKNYVKIIQRIGLVHLKPRIASWRYKRGTRSLATNLNQTTAAGGEPVVLEQSLEEGEEIVVPDAIEEVIEELLQALRSGGNDIRWSAAKGLGRVTNRLPKELADEVIGSVIDILNPLEPHEAWHGACLALAELAKRGLLLPHRLEELVPLLMQALFYDEMKGYMSVGQHIRDSACYMCWAFARAYNPDDVKPFVHKISSGLLTVAVFDREVNCRRAASAAFQESVGRLGNFPFGIEISTTTDFYSVGIRQNSYLNISDYIAQFEVYREPLINHLVQHKVSHWDSAIRELTAKALHKLSLWEPEYMAAVVLPQLLAKTDTIDINCRHGCVLAMGEITLTLRKLEEKSDPQVVYLSNQRVAELNELIITFLDKNFYRGMSGDLMKSCTSSYIKNCSLAKLQATPECLVSWQKVIDSCLITKSNAIRDGAVEAFGELCTTYYCSDSRHGENEAIINTYLTGADNDLEEHIRMGYIAALGVLPSFMIRCHLQAILDSLVKHSLTPLQAVLVGEMGDRENIQAYRWSEARTQSVLALTKLVKTVGYGGGIDSFAEPKNFNKVIECLLRALQEYTLDNRGDIGAWVREAAMSSLYEIVTTCPPDLLAPEQVHEIVVGFMQQAVEKIDRTRGLGGRLCCQLIHHQPRIPYIREHSKLLEIFPADADSVLWLFADHTFPLFCELLSLPDYSKRVLLGLSASIGQLTESLIKYASSALFHFLRSNPETVPRLCSEVVQIFEEHLLNERVTYPLLSFLDILIGSGTVESVLHDEANPFAEDIFRLLNLEVKGYKKLYKTATSISAFCQLLQVPRLSKRILSKLSVFLGLQHVHVRKTAATKLYEALALHGDVTEVPEENMDEILTLLSETDWTQPLVEVRPLRNQLCQLMDIKPPVSGAAAAAALQQASADK", "length": 1189 }, "evidence": [ { "id": "A0A8V1ANP8", "url": "https://omabrowser.org/oma/group/A0A8V1ANP8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "lateral plasma membrane", "id": "GO:0016328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "tubulin complex assembly", "id": "GO:0007021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "post-chaperonin tubulin folding pathway", "id": "GO:0007023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "negative regulation of microtubule polymerization", "id": "GO:0031115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "bicellular tight junction assembly", "id": "GO:0070830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070830", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "adherens junction assembly", "id": "GO:0034333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" }, { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1049, "end_pos": 1051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" }, { "id": "PF25767", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25767" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin-folding cofactor D ARM repeats", "eco_id": "ECO_0000259", "start_pos": 294, "end_pos": 442, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ANP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP8" }, { "id": "PF12612", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12612" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin-folding cofactor D C-terminal", "eco_id": "ECO_0000259", "start_pos": 935, "end_pos": 1122, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1049, "end_pos": 1051 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 742, "end_pos": 744 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1APT6-1", "uniprot_ac": "A0A8V1APT6", "uniprot_id": "A0A8V1APT6_CHICK", "mass": { "chemical_mass": 143862.0, "monoisotopic_mass": 143862.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Myosin tail domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1APT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6", "locus": {} } ], "crossref": [ { "id": "A0A8V1APT6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1APT6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQGQHCVLPLRHSLGNKSPTRGHPRWDEGHGAGHKGRAPCSRCCDTGGMLASHCAPPSRCFFRAGSLARLEEQRDTQTSRNITLFQAACRGFLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLTEEQIRGKDEEIQQLKSKLEKVEKERNELRLNSDRLESRITELTSELTDERNTGESASQLLDAETAERLRAEKEMKDLQAKYDALKKQMESMEMEVMEARLIRAAELNGELDDDDSGGEWRLKYERAVREIDFTKKRLQQELEDKLEVEQQGKRQLERRLADLQADGEESQRALQQLKKKCQRLAAELQDTKLHLEGQQGRNHDLEKKQRRFDGELSQAHEETQRERLQREKLSREKDVLVAEVFGLKQLLEDKDADIAGLTQRAEALEAELQDISCQESKDEASLAKVKKQLRDLEAKAKDQEEELDEQAGTIQMLEQAKLRLEMEMERLRQTHAKEVESRDEEVEEIRQSCQKKLKQMEMQLEEEYEDKQKVLREKRELESKLSAVSDQANQRDFETEKRLRRDLKRTKALLADAQIMLDHLKNNAPSKREIAQLKNQLEESEFTCAAAVKARKSMEVEIEDLHLQIDDLSKAKAALEEQLSRLQREKNEVQSRLEEDQEDMNELMKKHKAAVAQASRDLAQMNDLQAQLEEVSKEKQELQEKLQGLQSQLEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLATRLKENMEKLTEERDQRAAAENREKEQNKRLQRQLRDVKEEMGELAKKEAEASRKKHELEMDLESLEAANQSLQSDLKLAFKRIGDLQAAIEDEMESDSNEDLINSDGDSDVDSELEDRVDGVKSWLSKNKGSSKALSDDGSLKGSSRSAPADVPEGEERPVSVLSSLSYRKRPSLKDSIGGRGDEQTLFSALSERAASPERAARRARGTEHEDRAAVIARAFADASGRARQGLGKRWSLSAGDGEKGSVASAPVSRASSASWRAPEDGDEGDEGCSVLSFALSSPGSLRSRRSGADGRPDSRLSLARSLLDEADDASRGQPPLGRSFSVPPRPRSAASEDGPPGDARPVGHRSYLDPDLEAAIQEVLSYRSPRAGGLSSPDSGDDGRSVRSVRSAAPLGAADRPGSLRRSASALEVSRPSRRSGRRRSSSSSESSSSSSEEEEERKKKSAKKKSKKSKKKSKKKKKKSSSESGSDSSSDSSSGSTVSYRSTSSVKKGPRAAGGEEPVRPDRARKEEKRRKKQVDSLMMKYLYRPESD", "length": 1274, "header": "tr|A0A8V1APT6-1|A0A8V1APT6_CHICK Isoform 1 of Myosin tail domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1APT6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6/entry#A0A8V1AEP2-1", "sequence": { "sequence": "MLASHCAPPSRCFFRAGSLARLEEQRDTQTSRNITLFQAACRGFLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLTEEQIRGKDEEIQQLKSKLEKVEKERNELRLNSDRLESRITELTSELTDERNTGESASQLLDAETAERLRAEKEMKDLQAKYDALKKQMESMEMEVMEARLIRAAELNGELDDDDSGGEWRLKYERAVREIDFTKKRLQQELEDKLEVEQQGKRQLERRLADLQADGEESQRALQQLKKKCQRLAAELQDTKLHLEGQQGRNHDLEKKQRRFDGELSQAHEETQRERLQREKLSREKDVLVAEVFGLKQLLEDKDADIAGLTQRAEALEAELQDISCQESKDEASLAKVKKQLRDLEAKAKDQEEELDEQAGTIQMLEQAKLRLEMEMERLRQTHAKEVESRDEEVEEIRQSCQKKLKQMEMQLEEEYEDKQKVLREKRELESKLSAVSDQANQRDFETEKRLRRDLKRTKALLADAQIMLDHLKNNAPSKREIAQLKNQLEESEFTCAAAVKARKSMEVEIEDLHLQIDDLSKAKAALEEQLSRLQREKNEVQSRLEEDQEDMNELMKKHKAAVAQASRDLAQMNDLQAQLEEVSKEKQELQEKLQGLQSQLEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLEAANQSLQSDLKLAFKRIGDLQAAIEDEMESDSNEDLINSLQDMVAKYQKRKSKLDGDSDVDSELEDRVDGVKSWLSKNKGSSKALSDDGSLKGSSRSAPADVPEGEERPVSVLSSLSYRKRPSLKDSIGGRGDEQTLFSALSERAASPERAARRARGTEHEDRAAVIARAFADASGRARQGLGKRWSLSAGDGEKGSVASAPVSRASSASWRAPEDGDEGDEGCSVLSFALSSPGSLRSRRSGADGRPDSRLSLARSLLDEADDASRGQPPLGRSFSVPPRPRSAASEDGPPGDARPVGHRSYLDPDLEAAIQEVLSYRSPRAGGLSSPDSGDDGRSVRSVRSAAPLGAADRPGSLRRSASALEVSRPSRRSGRRRSSSSSESSSSSSEEEEERKKKSAKKKSKKSKKKSKKKKKKSSSESGSDSSSDSSSGSTVSYRSTSSVKKGPRAAGGEEPVRPDRARKEEKRRKKQVDSLMMKYLYRPESD", "length": 1173, "header": "tr|A0A8V1AEP2-1|A0A8V1APT6_CHICK Computationally mapped isoform of Myosin tail domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1APT6-1" }, "locus": { "chromosome": "19", "start_pos": 6426401, "end_pos": 6415687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071806.1", "url": "https://www.ensembl.org/id/ENSGALT00010071806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044496.1", "url": "https://www.ensembl.org/id/ENSGALP00010044496.1" } ] } }, { "isoform_ac": "A0A8V1APT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6/entry#A0A8V1APT6-1", "sequence": { "sequence": "MAQGQHCVLPLRHSLGNKSPTRGHPRWDEGHGAGHKGRAPCSRCCDTGGMLASHCAPPSRCFFRAGSLARLEEQRDTQTSRNITLFQAACRGFLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLTEEQIRGKDEEIQQLKSKLEKVEKERNELRLNSDRLESRITELTSELTDERNTGESASQLLDAETAERLRAEKEMKDLQAKYDALKKQMESMEMEVMEARLIRAAELNGELDDDDSGGEWRLKYERAVREIDFTKKRLQQELEDKLEVEQQGKRQLERRLADLQADGEESQRALQQLKKKCQRLAAELQDTKLHLEGQQGRNHDLEKKQRRFDGELSQAHEETQRERLQREKLSREKDVLVAEVFGLKQLLEDKDADIAGLTQRAEALEAELQDISCQESKDEASLAKVKKQLRDLEAKAKDQEEELDEQAGTIQMLEQAKLRLEMEMERLRQTHAKEVESRDEEVEEIRQSCQKKLKQMEMQLEEEYEDKQKVLREKRELESKLSAVSDQANQRDFETEKRLRRDLKRTKALLADAQIMLDHLKNNAPSKREIAQLKNQLEESEFTCAAAVKARKSMEVEIEDLHLQIDDLSKAKAALEEQLSRLQREKNEVQSRLEEDQEDMNELMKKHKAAVAQASRDLAQMNDLQAQLEEVSKEKQELQEKLQGLQSQLEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLATRLKENMEKLTEERDQRAAAENREKEQNKRLQRQLRDVKEEMGELAKKEAEASRKKHELEMDLESLEAANQSLQSDLKLAFKRIGDLQAAIEDEMESDSNEDLINSDGDSDVDSELEDRVDGVKSWLSKNKGSSKALSDDGSLKGSSRSAPADVPEGEERPVSVLSSLSYRKRPSLKDSIGGRGDEQTLFSALSERAASPERAARRARGTEHEDRAAVIARAFADASGRARQGLGKRWSLSAGDGEKGSVASAPVSRASSASWRAPEDGDEGDEGCSVLSFALSSPGSLRSRRSGADGRPDSRLSLARSLLDEADDASRGQPPLGRSFSVPPRPRSAASEDGPPGDARPVGHRSYLDPDLEAAIQEVLSYRSPRAGGLSSPDSGDDGRSVRSVRSAAPLGAADRPGSLRRSASALEVSRPSRRSGRRRSSSSSESSSSSSEEEEERKKKSAKKKSKKSKKKSKKKKKKSSSESGSDSSSDSSSGSTVSYRSTSSVKKGPRAAGGEEPVRPDRARKEEKRRKKQVDSLMMKYLYRPESD", "length": 1274, "header": "tr|A0A8V1APT6-1|A0A8V1APT6_CHICK Isoform 1 of Myosin tail domain-containing protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V1APT6-1" }, "locus": { "chromosome": "19", "start_pos": 6426548, "end_pos": 6415687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071807.1", "url": "https://www.ensembl.org/id/ENSGALT00010071807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044497.1", "url": "https://www.ensembl.org/id/ENSGALP00010044497.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6" } ], "pmid": "" }, { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 806, "end_pos": 808, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT6" }, { "id": "PF01576", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin tail", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 566, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 }, { "start_pos": 806, "end_pos": 808 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMQ5-1", "uniprot_ac": "A0A8V1AMQ5", "uniprot_id": "A0A8V1AMQ5_CHICK", "mass": { "chemical_mass": 51872.0, "monoisotopic_mass": 51872.0 }, "refseq": {}, "gene_names": [ { "name": "RBFOX3", "type": "recommended", "evidence": [ { "id": "A0A8V1AMQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ] } ], "protein_names": [ { "name": "RNA binding fox-1 homolog 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AMQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA-binding protein that regulates alternative splicing events.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AGV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV0#function" }, { "database": "UniProtKB", "id": "PIRNR037932", "url": "https://www.uniprot.org/uniprotkb/PIRNR037932#function" }, { "database": "UniProtKB", "id": "A0A8V1AGV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV5#function" }, { "database": "UniProtKB", "id": "A0A8V1AL20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL20#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBFOX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5", "locus": { "chromosome": "18", "start_pos": 10378760, "end_pos": 10294230, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029239", "url": "https://www.ensembl.org/id/ENSGALG00010029239" } ] } } ], "crossref": [ { "id": "A0A8V1AMQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857589", "url": "https://www.ncbi.nlm.nih.gov/gene/100857589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025670", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025670", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857589", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AAEPYHH", "url": "https://omabrowser.org/oma/group/AAEPYHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGV5", "url": "https://www.orthodb.org/?gene=A0A8V1AGV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15597", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15597", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15597:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15597:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ABK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCSMANSGCLLVSNSGMLPHSLPCPPAFLYLQQSNQDATAPPDAMAQPYPPAQYPPPPQNGIPAEYAPPHPHPTQDYSGQSTVPEHAMTLYTPAQSHAEQPGSDASTQSIAGTQTVPQTDEAAQTDSQQLHSSDNTDKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSTDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPATGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAASPSQPPLSVPLLQGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTMVRAAPAAFPCIPTRPTRAAAGPGGSGAAGRGAEQHSPRAAPSPAAPRERSVASLATSIKDEKSHLWAGSQAKRPFSSSLNWYLFFTLPHPPVEPWPPGPPPSPAPPSAHIVPMAAVGAPGEPALCTPRTEVN", "length": 489, "header": "tr|A0A8V1AMQ5-1|A0A8V1AMQ5_CHICK Isoform 1 of RNA binding fox-1 homolog 3 OS=Gallus gallus OX=9031 GN=RBFOX3 PE=4 SV=1 CANONICAL=A0A8V1AMQ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5/entry#A0A8V1ABK3-1", "sequence": { "sequence": "MAQPYPPAQYPPPPQNGIPAEYAPPHPHPTQDYSGQSTVPEHAMTLYTPAQSHAEQPGSDASTQSIAGTQTVPQTDEAAQTDSQQLHSSDNTDKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPATGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAASPSQPPLSVPLLQGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTMVRAAPAAFPCIPTRPTRAAAGPGGSGAAGRGAEQHSPRAAPSPAAPRERSVASLATSIKDEKSHLWAGSQAKRPFSSSLNWYLFFTLPHPPVEPWPPGPPPSPAPPSAHIVPMAAVGAPGEPALCTPRTEVN", "length": 413, "header": "tr|A0A8V1ABK3-1|A0A8V1ABK3_CHICK Computationally mapped isoform of RNA binding fox-1 homolog 3 OS=Gallus gallus OX=9031 GN=RBFOX3 PE=4 SV=1 CANONICAL=A0A8V1AMQ5-1" }, "locus": { "chromosome": "18", "start_pos": 10378176, "end_pos": 10372463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070672.1", "url": "https://www.ensembl.org/id/ENSGALT00010070672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043363.1", "url": "https://www.ensembl.org/id/ENSGALP00010043363.1" } ] } }, { "isoform_ac": "A0A8V1AGV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5/entry#A0A8V1AGV0-1", "sequence": { "sequence": "MAAGGTGTIVLAPQLSSPPREPSVSTAGGTWLHKGMLPHSLPCPPAFLYLQQSNQDATAPPDAMAQPYPPAQYPPPPQNGIPAEYAPPHPHPTQDYSGQSTVPEHAMTLYTPAQSHAEQPGSDASTQSIAGTQTVPQTDEAAQTDSQQLHSSDNTDKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSTDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPATGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTM", "length": 374, "header": "tr|A0A8V1AGV0-1|A0A8V1AMQ5_CHICK Computationally mapped isoform of RNA binding fox-1 homolog 3 OS=Gallus gallus OX=9031 GN=RBFOX3 PE=4 SV=1 CANONICAL=A0A8V1AMQ5-1" }, "locus": { "chromosome": "18", "start_pos": 10377780, "end_pos": 10334339, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070669.1", "url": "https://www.ensembl.org/id/ENSGALT00010070669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043360.1", "url": "https://www.ensembl.org/id/ENSGALP00010043360.1" } ] } }, { "isoform_ac": "A0A8V1AGV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5/entry#A0A8V1AGV5-1", "sequence": { "sequence": "MLCSMANSGCLLVSNSGMLPHSLPCPPAFLYLQQSNQDATAPPDAMAQPYPPAQYPPPPQNGIPAEYAPPHPHPTQDYSGQSTVPEHAMTLYTPAQSHAEQPGSDASTQSIAGTQTVPQTDEAAQTDSQQLHSSDNTDKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSTDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPATGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTMASLYRGGYSRFTPY", "length": 370, "header": "tr|A0A8V1AGV5-1|A0A8V1AMQ5_CHICK Computationally mapped isoform of RNA binding fox-1 homolog 3 OS=Gallus gallus OX=9031 GN=RBFOX3 PE=4 SV=1 CANONICAL=A0A8V1AMQ5-1" }, "locus": { "chromosome": "18", "start_pos": 10378336, "end_pos": 10361978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070674.1", "url": "https://www.ensembl.org/id/ENSGALT00010070674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043365.1", "url": "https://www.ensembl.org/id/ENSGALP00010043365.1" } ] } }, { "isoform_ac": "A0A8V1AIY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5/entry#A0A8V1AIY3-1", "sequence": { "sequence": "MCSSLAAQGWDLPAAKHELGGSACSLWAFSPLAPGGRLLKPGVVLLWLESANCCAHVELVGEPSVSTAGGTWLHKGMLPHSLPCPPAFLYLQQSNQDATAPPDAMAQPYPPAQYPPPPQNGIPAEYAPPHPHPTQDYSGQSTVPEHAMTLYTPAQSHAEQPGSDASTQSIAGTQTVPQTDEAAQTDSQQLHSSDNTDKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSTDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPATGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTM", "length": 415, "header": "tr|A0A8V1AIY3-1|A0A8V1AMQ5_CHICK Computationally mapped isoform of RNA binding fox-1 homolog 3 OS=Gallus gallus OX=9031 GN=RBFOX3 PE=4 SV=1 CANONICAL=A0A8V1AMQ5-1" }, "locus": { "chromosome": "18", "start_pos": 10377780, "end_pos": 10329194, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070671.1", "url": "https://www.ensembl.org/id/ENSGALT00010070671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043362.1", "url": "https://www.ensembl.org/id/ENSGALP00010043362.1" } ] } }, { "isoform_ac": "A0A8V1AL20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5/entry#A0A8V1AL20-1", "sequence": { "sequence": "MAQPYPPAQYPPPPQNGIPAEYAPPHPHPTQDYSGQSTVPEHAMTLYTPAQSHAEQPGSDASTQSIAGTQTVPQTDEAAQTDSQQLHSSDNTDKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSTDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPATGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTMASLYRGGYSRFTPY", "length": 325, "header": "tr|A0A8V1AL20-1|A0A8V1AMQ5_CHICK Computationally mapped isoform of RNA binding fox-1 homolog 3 OS=Gallus gallus OX=9031 GN=RBFOX3 PE=4 SV=1 CANONICAL=A0A8V1AMQ5-1" }, "locus": { "chromosome": "18", "start_pos": 10378336, "end_pos": 10372463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070670.1", "url": "https://www.ensembl.org/id/ENSGALT00010070670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043361.1", "url": "https://www.ensembl.org/id/ENSGALP00010043361.1" } ] } }, { "isoform_ac": "A0A8V1AMQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5/entry#A0A8V1AMQ5-1", "sequence": { "sequence": "MLCSMANSGCLLVSNSGMLPHSLPCPPAFLYLQQSNQDATAPPDAMAQPYPPAQYPPPPQNGIPAEYAPPHPHPTQDYSGQSTVPEHAMTLYTPAQSHAEQPGSDASTQSIAGTQTVPQTDEAAQTDSQQLHSSDNTDKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSTDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPATGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAASPSQPPLSVPLLQGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTMVRAAPAAFPCIPTRPTRAAAGPGGSGAAGRGAEQHSPRAAPSPAAPRERSVASLATSIKDEKSHLWAGSQAKRPFSSSLNWYLFFTLPHPPVEPWPPGPPPSPAPPSAHIVPMAAVGAPGEPALCTPRTEVN", "length": 489, "header": "tr|A0A8V1AMQ5-1|A0A8V1AMQ5_CHICK Isoform 1 of RNA binding fox-1 homolog 3 OS=Gallus gallus OX=9031 GN=RBFOX3 PE=4 SV=1 CANONICAL=A0A8V1AMQ5-1" }, "locus": { "chromosome": "18", "start_pos": 10378176, "end_pos": 10361978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070673.1", "url": "https://www.ensembl.org/id/ENSGALT00010070673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043364.1", "url": "https://www.ensembl.org/id/ENSGALP00010043364.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857589", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MKN0-1", "protein_name": "RNA binding protein fox-1 homolog 3", "gene_name": "Rbfox3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTQDYSGQTPVPPEHGMTLYTPAQTHPEQPGTEASTQPITGTQTVPQADEAAQTDSQQLHPSDPTEKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKPGNPYANGWKLNPVVGAVYGPEFYAVTSFPYPTTGTTVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAAAYSDSYGRVYAATDPYHHTIGPTATYSIGTMASLCRGGYSRFTPY", "length": 375 }, "evidence": [ { "id": "A0A8V1AMQ5", "url": "https://omabrowser.org/oma/group/A0A8V1AMQ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A6NFN3-1", "protein_name": "RNA binding protein fox-1 homolog 3", "gene_name": "RBFOX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTQDYSGQTPVPTEHGMTLYTPAQTHPEQPGSEASTQPIAGTQTVPQTDEAAQTDSQPLHPSDPTEKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTGNPYTNGWKLNPVVGAVYGPEFYAVTGFPYPTTGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTM", "length": 312 }, "evidence": [ { "id": "A0A8V1AMQ5", "url": "https://omabrowser.org/oma/group/A0A8V1AMQ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A2H6-1", "protein_name": "RNA binding protein fox-1 homolog 3", "gene_name": "Rbfox3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTQDYSGQTPVPPEHGMTLYTPAQTHPEQPGTEASTQPIAGTQTVPQADEAAQTDSQQLHPSDPTEKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKPGNPYANGWKLNPVVGAVYGPEFYAVTSFPYPTTGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAAAYSDSYGRVYAAADPYHHTIGPTATYSIGTMASLCRGGYSRFTPY", "length": 375 }, "evidence": [ { "id": "A0A8V1AMQ5", "url": "https://omabrowser.org/oma/group/A0A8V1AMQ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VD23-1", "protein_name": "RNA binding protein fox-1 homolog 3", "gene_name": "RBFOX3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTPDYSGQTPVPPEHGMTLYTPAQTHPEQPSSDTSTQPITGAQTVPQTDEAAQTDSQPLHPSDPTEKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKVNNATARVMTNKKTANPYTNGWKLNPVVGAVYGPEFYAVTGFPYPTTGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAYSDSYGRVYAAADPYHHTIGPAATYSIGTM", "length": 328 }, "evidence": [ { "id": "A0A8V1AMQ5", "url": "https://omabrowser.org/oma/group/A0A8V1AMQ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BIF2-1", "protein_name": "RNA binding protein fox-1 homolog 3", "gene_name": "Rbfox3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQPYPPAQYPPPPQNGIPAEYAPPPPHPTQDYSGQTPVPPEHGMTLYTPAQTHPEQPGTEASTQPIAGTQTVPQADEAAQTDNQQLHPSDPTEKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKPGNPYANGWKLNPVVGTVYGPEFYAVTSFPYPTTGTAVAYRGAHLRGRGRAVYNTFRAAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQPAAATAAAYSDSYGRVYAAADPYHHTIGPTATYSIGTMASLCRGGYSRFTPY", "length": 374 }, "evidence": [ { "id": "A0A8V1AMQ5", "url": "https://omabrowser.org/oma/group/A0A8V1AMQ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ5" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 219, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AP69-1", "uniprot_ac": "A0A8V1AP69", "uniprot_id": "A0A8V1AP69_CHICK", "mass": { "chemical_mass": 52353.0, "monoisotopic_mass": 52353.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM58", "type": "recommended", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69", "locus": {} } ], "crossref": [ { "id": "A0A8V1AP69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP69", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16594", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16594", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19762", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19762", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ24", "url": "https://www.orthodb.org/?gene=A0A8V1AJ24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP69", "url": "https://www.orthodb.org/?gene=A0A8V1AP69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3134975", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134975", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-844456", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-844456", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9755511", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AJ24", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSEALERLDEEAICSICLEYMSEPVSVDCGHNFCRSCIGKHCQEKGLWNDTPFSCPQCRAPCRRSSLRPNRQLANIVESIRQLGLRGSVGTATETGAGTLLCPLHNERLKLFCEVDEQPICVVCRESQQHRSHTVYPIEEAAQGYKEKVKRKRETIVCEFGKLHQLLADEEKLLLQKLEEEETQILVMISENLARVTEQKCSLVELILEIKEKMQQPVEVLLKDRRCILNRCEMMKFQAPKPVSVNLKEDYSIPERCMGMRHMLRKFKVDVTLDPETANLELILSEDRKSVRRGSRKLFLLLFDSPKRFNCAPVVLGLQAFFSGRSYWEVQVGDKPEWGLGLCKEAAGRRGNIVFSPQNGYWVLRLQNGGYEALTCPVSCLTLRVRPRCIGIFLDYEAGEISFYNVSDRSHLYTFTDKFSGKLRPFFYLGSLMGGKNAEPLVISWMRDTQGTSCVVL", "length": 459, "header": "tr|A0A8V1AP69-1|A0A8V1AP69_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM58 PE=3 SV=1 CANONICAL=A0A8V1AP69-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69/entry#A0A8V1AJ24-1", "sequence": { "sequence": "MALSEALERLDEEAICSICLEYMSEPVSVDCGHNFCRSCIGKHCQEKGLWNDTPFSCPQCRAPCRRSSLRPNRQLANIVESIRQLGLRGSVGTATETGAGTLLCPLHNERLKLFCEVDEQPICVVCRESQQHRSHTVYPIEEAAQGYKVKLQKCLEQLSKEVEDMKKRESEAKMKTQECKEKVKRKRETIVCEFGKLHQLLADEEKLLLQKLEEEETQILVMISENLARVTEQKCSLVELILEIKEKMQQPVEVLLKDRRCILNRCEMMKFQAPKPVSVNLKEDYSIPERCMGMRHMLRKFKVDVTLDPETANLELILSEDRKSVQVGDKPEWGLGLCKEAAGRRGNIVFSPQNGYWVLRLQNGGYEALTCPVSCLTLRVRPRCIGIFLDYEAGEISFYNVSDRSHLYTFTDKFSGKLRPFFYLGSLMGGKNAEPLVISWMRDTQGTSCVVL", "length": 452, "header": "tr|A0A8V1AJ24-1|A0A8V1AP69_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM58 PE=3 SV=1 CANONICAL=A0A8V1AP69-1" }, "locus": { "chromosome": "19", "start_pos": 901496, "end_pos": 896535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071447.1", "url": "https://www.ensembl.org/id/ENSGALT00010071447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044137.1", "url": "https://www.ensembl.org/id/ENSGALP00010044137.1" } ] } }, { "isoform_ac": "A0A8V1AP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69/entry#A0A8V1AP69-1", "sequence": { "sequence": "MALSEALERLDEEAICSICLEYMSEPVSVDCGHNFCRSCIGKHCQEKGLWNDTPFSCPQCRAPCRRSSLRPNRQLANIVESIRQLGLRGSVGTATETGAGTLLCPLHNERLKLFCEVDEQPICVVCRESQQHRSHTVYPIEEAAQGYKEKVKRKRETIVCEFGKLHQLLADEEKLLLQKLEEEETQILVMISENLARVTEQKCSLVELILEIKEKMQQPVEVLLKDRRCILNRCEMMKFQAPKPVSVNLKEDYSIPERCMGMRHMLRKFKVDVTLDPETANLELILSEDRKSVRRGSRKLFLLLFDSPKRFNCAPVVLGLQAFFSGRSYWEVQVGDKPEWGLGLCKEAAGRRGNIVFSPQNGYWVLRLQNGGYEALTCPVSCLTLRVRPRCIGIFLDYEAGEISFYNVSDRSHLYTFTDKFSGKLRPFFYLGSLMGGKNAEPLVISWMRDTQGTSCVVL", "length": 459, "header": "tr|A0A8V1AP69-1|A0A8V1AP69_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM58 PE=3 SV=1 CANONICAL=A0A8V1AP69-1" }, "locus": { "chromosome": "19", "start_pos": 901496, "end_pos": 896535, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071446.1", "url": "https://www.ensembl.org/id/ENSGALT00010071446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044136.1", "url": "https://www.ensembl.org/id/ENSGALP00010044136.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-3134975", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134975", "resource": "Reactome", "description": "Regulation of innate immune responses to cytosolic DNA" }, { "id": "R-GGA-844456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-844456", "resource": "Reactome", "description": "The NLRP3 inflammasome" }, { "id": "R-GGA-9755511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755511", "resource": "Reactome", "description": "KEAP1-NFE2L2 pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-3134946", "name": "DDX41 ubiquitination by TRIM21", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP69-1", "A0A8V0Y242-1" ], "evidence": [ { "id": "R-GGA-3134946", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3134946" } ] }, { "id": "R-GGA-879221", "name": "PSTPIP1 binds Pyrin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP69-1" ], "evidence": [ { "id": "R-GGA-879221", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-879221" } ] }, { "id": "R-GGA-9759154", "name": "TRIM21 ubiquitinates SQSTM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-GGA-193937" ], "output_participant_list": [ "R-GGA-9759088" ], "enzyme_list": [ "A0A8V1AP69-1" ], "evidence": [ { "id": "R-GGA-9759154", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9759154" } ] }, { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-193937", "participant_name": "SQSTM1 [cytosol]", "crossref": [ { "id": "ENSGALG00010016907", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010023771", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010040807", "database": "ENSEMBL", "url": "" }, { "id": "XP_040538686.1", "database": "RefSeq", "url": "" }, { "id": "XP_001233249.2", "database": "RefSeq", "url": "" }, { "id": "A0A1D5PLN4", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-GGA-9759088", "participant_name": "SQSTM1 [cytosol]", "crossref": [ { "id": "XP_040538686.1", "database": "RefSeq", "url": "" }, { "id": "ENSGALP00010023771", "database": "ENSEMBL", "url": "" }, { "id": "A0A1D5PLN4", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010016907", "database": "ENSEMBL", "url": "" }, { "id": "XP_001233249.2", "database": "RefSeq", "url": "" }, { "id": "ENSGALT00010040807", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": 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"https://www.ensembl.org/id/ENSGALG00010029440" } ] } } ], "crossref": [ { "id": "A0A8V1ANS6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427798", "url": "https://www.ncbi.nlm.nih.gov/gene/427798", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107049008", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049008", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMKPVTY", "url": "https://omabrowser.org/oma/group/AMKPVTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AD14", "url": "https://www.orthodb.org/?gene=A0A8V1AD14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK98", "url": "https://www.orthodb.org/?gene=A0A8V1AK98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANS6", "url": "https://www.orthodb.org/?gene=A0A8V1ANS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45881", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45881", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45881:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45881:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AD14", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK98", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPLTMSLPTKRCGRPPVLSFLEKKKRKQSLDRRRGKTRIYVGNHIDRWLTLKEKLDFRNDAEVAGFLLDLYDSYDPLTKAPICSLPGGVRRISVKEERALSGSACLIAADGTYDDGDRLSEEAACSEYGDYRIVTVKEERETPPHCSSVKTDNTCTFRFPSTNIKITFTALSNEKREKQEAPESPVKPVQPQISPLTINIPDNMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMSRVIPSDLHLMADNSQSENDKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPESLSREGSPVPMEPEPSAIQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQTIKPVTYTVATPVTTSTSQQPVVQTVHVVHQIPAVSVTNVTGLAPANTYTVAGQAVVTQAAMVTQPKVEPQENGDHKEVKVKVEPIPAISHATIGAASRIIQTSQTTPLQTVTIVQQAPLGQHQLPIKTVTQNGTHIVPITTAIQGQGNAAAASPLHMLATHASASASLPTKRQNGDQSEQQELKRIKTEDGESIVIAVNVDTPPVAVSDKGSQN", "length": 675, "header": "tr|A0A8V1ANS6-1|A0A8V1ANS6_CHICK Isoform 1 of Forkhead box K2 OS=Gallus gallus OX=9031 GN=FOXK2 PE=4 SV=1 CANONICAL=A0A8V1ANS6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6/entry#A0A8V1AD14-1", "sequence": { "sequence": "MSLPTKRCGRPPVLSFLEKKKRKQSLDRRRGKTRIYVGNHIDRWLTLKEKLDFRNDAEVAGFLLDLYDSYDPLTKAPICSLPGGVRRISVKEERALSGSACLIAADGTYDDGDRLSEEAACSEYGDYRIVTVKEERETPPHCSSVKTDNTCTFRFPSTNIKITFTALSNEKREKQEAPESPVKPVQPQISPLTINIPDNMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMSRVIPSDLHLMADNSQSENDKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPESLSREGSPVPMEPEPSAIQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQTIKPVTYTVATPVTTSTSQQPVVQTVHVVHQIPAVSVTNVTGLAPANTYTVAGQAVVTQAAMVTQPKVEPQENGDHKEVKVKVEPIPAISHATIGAASRIIQTSQTTPLQTVTIVQQAPLGQHQLPIKTVTQNGTHIVPITTAIQGQGNAAAASPLHMLATHASASASLPTKRQNGDQSEQQELKRIKTEDGESIVIAVNVDTPPVAVSDKGSQN", "length": 670, "header": "tr|A0A8V1AD14-1|A0A8V1AD14_CHICK Computationally mapped isoform of Forkhead box K2 OS=Gallus gallus OX=9031 GN=FOXK2 PE=4 SV=1 CANONICAL=A0A8V1ANS6-1" }, "locus": { "chromosome": "18", "start_pos": 4094678, "end_pos": 4036211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071218.1", "url": "https://www.ensembl.org/id/ENSGALT00010071218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043909.1", "url": "https://www.ensembl.org/id/ENSGALP00010043909.1" } ] } }, { "isoform_ac": "A0A8V1AK98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6/entry#A0A8V1AK98-1", "sequence": { "sequence": "MAAAAAAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTAAPPPPPPAGADGPPPPAQGDPAAAGGGGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSNEKREKQEAPESPVKPVQPQISPLTINIPDNMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMSRVIPSDLHLMADNSQSENDKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPESLSREGSPVPMEPEPSAIQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQTIKPVTYTVATPVTTSTSQQPVVQTVHVVHQIPAVSVTNVTGLAPANTYTVAGQAVVTQAAMVTQPKVEPQENGDHKEVKVKVEPIPAISHATIGAASRIIQTSQTTPLQTVTIVQQAPLGQHQLPIKTVTQNGTHIVPITTAIQGQGNAAAASPLHMLATHASASASLPTKRQNGDQSEQQELKRIKTEDGESIVIAVNVDTPPVAVSDKGSQN", "length": 636, "header": "tr|A0A8V1AK98-1|A0A8V1ANS6_CHICK Computationally mapped isoform of Forkhead box K2 OS=Gallus gallus OX=9031 GN=FOXK2 PE=4 SV=1 CANONICAL=A0A8V1ANS6-1" }, "locus": { "chromosome": "18", "start_pos": 4075685, "end_pos": 4036211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071217.1", "url": "https://www.ensembl.org/id/ENSGALT00010071217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043908.1", "url": "https://www.ensembl.org/id/ENSGALP00010043908.1" } ] } }, { "isoform_ac": "A0A8V1ANS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6/entry#A0A8V1ANS6-1", "sequence": { "sequence": "MLPLTMSLPTKRCGRPPVLSFLEKKKRKQSLDRRRGKTRIYVGNHIDRWLTLKEKLDFRNDAEVAGFLLDLYDSYDPLTKAPICSLPGGVRRISVKEERALSGSACLIAADGTYDDGDRLSEEAACSEYGDYRIVTVKEERETPPHCSSVKTDNTCTFRFPSTNIKITFTALSNEKREKQEAPESPVKPVQPQISPLTINIPDNMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMSRVIPSDLHLMADNSQSENDKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPESLSREGSPVPMEPEPSAIQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQTIKPVTYTVATPVTTSTSQQPVVQTVHVVHQIPAVSVTNVTGLAPANTYTVAGQAVVTQAAMVTQPKVEPQENGDHKEVKVKVEPIPAISHATIGAASRIIQTSQTTPLQTVTIVQQAPLGQHQLPIKTVTQNGTHIVPITTAIQGQGNAAAASPLHMLATHASASASLPTKRQNGDQSEQQELKRIKTEDGESIVIAVNVDTPPVAVSDKGSQN", "length": 675, "header": "tr|A0A8V1ANS6-1|A0A8V1ANS6_CHICK Isoform 1 of Forkhead box K2 OS=Gallus gallus OX=9031 GN=FOXK2 PE=4 SV=1 CANONICAL=A0A8V1ANS6-1" }, "locus": { "chromosome": "18", "start_pos": 4095419, "end_pos": 4036211, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071219.1", "url": "https://www.ensembl.org/id/ENSGALT00010071219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043910.1", "url": "https://www.ensembl.org/id/ENSGALP00010043910.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107049008", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049008", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A5H3-1", "protein_name": "Forkhead box protein K2", "gene_name": "Foxk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAALSGAGAPPAGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGHSAAAPEPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVAVTSVAGLAPANTYTVAGQAVVTQAAVLAPKTEPQENGDHREVRVKVEPVPAISPATLGAASRIIQTSQGTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVVPMPTAVHSQVNNAVASPLHMLATHASASASLPTKRQNGDQAEQPELKRVKAEDGESIVIALSVDAPPAAVREKAIQN", "length": 650 }, "evidence": [ { "id": "A0A8V1ANS6", "url": "https://omabrowser.org/oma/group/A0A8V1ANS6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FFM9-1", "protein_name": "Forkhead box protein K2", "gene_name": "foxk2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAMARLEGREFEYVMKKRSVTVGRNSSQGSVDVSMGHSSFISRRHLEIFTAAAEDTGSGPGGGDFYLRCLGKNGVFVDGVFLRRGAPPLQLPRVCTFRFPSTNIKITFTALASVKREKREPESPVKAVQPQISPLTINIPDNIAHLMSPLPSPTGTISAANSCPSSPRGAGSSGYRLGRIVPDLQLMNDNSQSENDKETSEGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPSSEGKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHSGVLSAHSSGVQTPDSLSREGSPVPMESEPVSVPPPAAVAVAAVQPKLAVIQETRFTQNTTASPITTQPVLIAVQRPLTQNMKPVTYAVAAPVSSSTSAQPLMQTVHVVHQIPAVAVSTVKTEPRENGDYDELKVKVEAVPGIAHGSIGTANRVIQTSAAATPLQTVTIVQQAPLGQHQLPIKTITQNGTHVVPIATAIQSQANTVSSPLHLLAAHASASASLPTKRQNGEKASDPPESKRLKTEDEEQKVSSDPNGSAADTDSANHN", "length": 597 }, "evidence": [ { "id": "A0A8V1ANS6", "url": "https://omabrowser.org/oma/group/A0A8V1ANS6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S012-1", "protein_name": "Forkhead box protein K2", "gene_name": "FOXK2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAAALPGAGGPPAGGGAGGGGGAGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPEPSAQPGPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKRETQEAPESPVKPVQAHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSGQPVLIAVQRPLPPTIKPVTYTVTTPVTTSTSQQPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPKAEPQENGDHREVKVKVEPIPAISHATLGAAGRIIQTPQATPVQTVTIVQQAPLGQHQLPIKAVTQNGTHVVPIPAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDPAEQPELKRVKTEDGEGIVIALSVDAPAAGREKGVQN", "length": 656 }, "evidence": [ { "id": "A0A8V1ANS6", "url": "https://omabrowser.org/oma/group/A0A8V1ANS6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q01167-1", "protein_name": "Forkhead box protein K2", "gene_name": "FOXK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN", "length": 660 }, "evidence": [ { "id": "A0A8V1ANS6", "url": "https://omabrowser.org/oma/group/A0A8V1ANS6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UCQ1-1", "protein_name": "Forkhead box protein K2", "gene_name": "Foxk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAALSGAGAPPAGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGHSAAAPEPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEAPESPVKPVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLSLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGASQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPPAIKPVTYTVATPVTTPTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVAGQAVVTQAAVLAPPNPEPQENGDHREVRVKVEPVPAISPATLGAASRIIQTSQGTPVQTVTIVQQAPLGQHQLPIKTVTQNGAHVVPMPTAVHSQVNNAAASPLHMLATHASASASLPTKRQNGDQAEQPELKRVKAEDGESIVIALSVDAPPAAVREKAIQN", "length": 651 }, "evidence": [ { "id": "A0A8V1ANS6", "url": "https://omabrowser.org/oma/group/A0A8V1ANS6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "response to starvation", "id": "GO:0042594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "regulation of glucose metabolic process", "id": "GO:0010906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010906", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" }, { "name": "intracellular glucose homeostasis", "id": "GO:0001678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001678", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANS6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1APK7-1", "uniprot_ac": "A0A8V1APK7", "uniprot_id": "A0A8V1APK7_CHICK", "mass": { "chemical_mass": 64671.0, "monoisotopic_mass": 64671.0 }, "refseq": { "ac": "XP_046758208", "name": "epsin-3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758208" }, "gene_names": [ { "name": "EPN3", "type": "recommended", "evidence": [ { "id": "A0A8V1APK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7" } ] }, { "name": "EPN3", "type": "synonym", "evidence": [ { "id": "XP_046758208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758208" } ] } ], "protein_names": [ { "name": "Epsin 3", "type": "synonym", "evidence": [ { "id": "A0A8V1APK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7/entry#names_and_taxonomy" } ] }, { "name": "epsin-3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046758208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758208" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758208" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EPN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7", "locus": { "chromosome": "18", "start_pos": 10948860, "end_pos": 10956744, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029638", "url": "https://www.ensembl.org/id/ENSGALG00010029638" } ] } } ], "crossref": [ { "id": "A0A8V1APK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1APK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023279", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023279", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859290", "url": "https://www.ncbi.nlm.nih.gov/gene/100859290", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859290", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859290", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SGTHESA", "url": "https://omabrowser.org/oma/group/SGTHESA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APK7", "url": "https://www.orthodb.org/?gene=A0A8V1APK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZR2", "url": "https://www.orthodb.org/?gene=F1NZR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12276:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12276:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046758208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758208", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1APK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZR2", "url": "https://www.uniprot.org/uniprotkb/F1NZR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZR2-1", "url": "https://www.uniprot.org/uniprotkb/F1NZR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMIWRRLNDSGKNWRHVYKALTLLDYLIKTGSEKVTHQCRENLYTIQTLKDFQYVDRDGKDQGINIREKVKQVMALLKDEERLKQERAHALQTKERMALEGMGSGSHQSTYGRRASPYGDDYGRTRGSPSSFNSSSSSPRFASDLEQARPQTTGEEELQLQLALAMSREEAEKEVRAWQGENSLLQRALEETAQGGEEEEEEDKMKKSQSSILELADIFGPAPAPSGHTSADPWDMPDMKPKAEPAAWTGTADPWVPVLSSSGEPVPQAGTTSQQTAAGPWDFPPASADPWGKAPASSGFSPADPWTATSPPAQGSGTTPATDPWAAVAEPNPNPAAGGDAFDLFAKQPEAAEQPEMEHSQPPSSVKSSSPAELDPFGDLFPGTKQDAAKSFDLANLADSLPESCKERKDCKTPEAFLGPAASSLVNLDSLVAPPQAAKTRNPFLSGLSTPSPTNPFSLAEQPKPTLNQMRTGSPVPGLPAALPANAMTYSTSLPLPLSSVPAALPASASAFPQAGAGPFPELPGALPQPLLPLSGPPAPQGGLNPFL", "length": 605, "header": "tr|A0A8V1APK7-1|A0A8V1APK7_CHICK Isoform 1 of Epsin 3 OS=Gallus gallus OX=9031 GN=EPN3 PE=1 SV=1 CANONICAL=A0A8V1APK7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1APK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7/entry#A0A8V1APK7-1", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMIWRRLNDSGKNWRHVYKALTLLDYLIKTGSEKVTHQCRENLYTIQTLKDFQYVDRDGKDQGINIREKVKQVMALLKDEERLKQERAHALQTKERMALEGMGSGSHQSTYGRRASPYGDDYGRTRGSPSSFNSSSSSPRFASDLEQARPQTTGEEELQLQLALAMSREEAEKEVRAWQGENSLLQRALEETAQGGEEEEEEDKMKKSQSSILELADIFGPAPAPSGHTSADPWDMPDMKPKAEPAAWTGTADPWVPVLSSSGEPVPQAGTTSQQTAAGPWDFPPASADPWGKAPASSGFSPADPWTATSPPAQGSGTTPATDPWAAVAEPNPNPAAGGDAFDLFAKQPEAAEQPEMEHSQPPSSVKSSSPAELDPFGDLFPGTKQDAAKSFDLANLADSLPESCKERKDCKTPEAFLGPAASSLVNLDSLVAPPQAAKTRNPFLSGLSTPSPTNPFSLAEQPKPTLNQMRTGSPVPGLPAALPANAMTYSTSLPLPLSSVPAALPASASAFPQAGAGPFPELPGALPQPLLPLSGPPAPQGGLNPFL", "length": 605, "header": "tr|A0A8V1APK7-1|A0A8V1APK7_CHICK Isoform 1 of Epsin 3 OS=Gallus gallus OX=9031 GN=EPN3 PE=1 SV=1 CANONICAL=A0A8V1APK7-1" }, "locus": { "chromosome": "18", "start_pos": 10954435, "end_pos": 10949491, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071662.1", "url": "https://www.ensembl.org/id/ENSGALT00010071662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044352.1", "url": "https://www.ensembl.org/id/ENSGALP00010044352.1" } ] } }, { "isoform_ac": "F1NZR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7/entry#F1NZR2-1", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMIWRRLNDSGKNWRHVYKALTLLDYLIKTGSEKVTHQCRENLYTIQTLKDFQYVDRDGKDQGINIREKVKQVMALLKDEERLKQERAHALQTKERMALEGMGSGSHQSTYGRRASPYGDDYGRTRGSPSSFNSSSSSPRFASDLEQARPQTTGEEELQLQLALAMSREEAEKKPLPPISSTDEERQLQLALALSKEEHEKEVRAWQGENSLLQRALEETAQGGEEEEEEDKMKKSQSSILELADIFGPAPAPSGHTSADPWDMPDMKPKAEPAAWTGTADPWVPVLSSSGEPVPQAGTTSQQTAAGPWDFPPASADPWGKAPASSGFSPADPWTATSPPAQGSGTTPATDPWAAVAEPNPNPAAGGDAFDLFAKQPEAAEQPEMEHSQPPSSVKSSSPAELDPFGDLFPGTKQDAAKSFDLANLADSLPESCKERKDCKTPEAFLGPAASSLVNLDSLVAPPQAAKTRNPFLSGLSTPSPTNPFSLAEQPKPTLNQMRTGSPVPGLPAALPANAMTYSTSLPLPLSSVPAALPASASAFPQAGAGPFPELPGALPQPLLPLSGPPAPQGGLNPFL", "length": 633, "header": "tr|F1NZR2-1|A0A8V1APK7_CHICK Computationally mapped isoform of Epsin 3 OS=Gallus gallus OX=9031 GN=EPN3 PE=1 SV=4 CANONICAL=A0A8V1APK7-1" }, "locus": { "chromosome": "18", "start_pos": 10954435, "end_pos": 10949491, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071661.1", "url": "https://www.ensembl.org/id/ENSGALT00010071661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044351.1", "url": "https://www.ensembl.org/id/ENSGALP00010044351.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 376, "start_aa": "Thr", "end_pos": 376, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr376", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859290", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859290", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N4F8-1", "protein_name": "Epsin 3", "gene_name": "EPN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYVDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGTGISSGQLGLSRARGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKEVRSWQGDDSPVANGAGAGAHRRWDREPERAEREEEKLKTSQSSSLDLVDIFASASTLPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGSIMSQSQPWDLPPVLSSSEPWGRTPVLPAGPPTTDFWAQNSPHHKLPNNGAKPWGNLVETFNTPALDGSSTFDPLAKPPVSTETKEGLECTQALPSGKPSSPVELDLFGDHTPSVKQNGTKEPDAFDLDVLGEALAQSSRDTPARRTPESFLGPSASSLVNLDSLVKVPQAVKTRNPFLTGLSTPSPTNPFGGGDQSRRTLNQMRTGSPALSLTAGGPIGAPFGSMTYSASLPLPLSSVPAGVTLPASVSVFPQARAFTPPPSGSLPQPLLPTSGSAGPLNQTPLTDTNPFL", "length": 608 }, "evidence": [ { "id": "A0A8V1APK7", "url": "https://omabrowser.org/oma/group/A0A8V1APK7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V882-1", "protein_name": "Epsin-3", "gene_name": "Epn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGFSRRSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAEKGGRSWKGDDFPVANGAEPAGQRRRDREPEREERKEEEKLKTSQSSILDLADVFAPAPALPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGNALSRSQPWDLLPTLSSSEPWGRTPVLPSGPPITDPWAPSSPTPKLPSTGVDPWGASVETSNTSALGGASPFDPFAKPLESTEPMESRDSAQALPKGKSPSPVELDPFGDSSPSCKQNGVKETEALDLGVLGEALTQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNPFLTGLSAPSPTNPFGAGEQGRPTLNQMRTGSPALGLPPGGPVGVPLGSMTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPASLPQPLLPTSDPVGPLPPQAGTNPFL", "length": 608 }, "evidence": [ { "id": "A0A8V1APK7", "url": "https://omabrowser.org/oma/group/A0A8V1APK7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91W69-1", "protein_name": "Epsin-3", "gene_name": "Epn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGYSRRSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAERPVPPASHRDEDLQLQLALSLSRQEHEKGVRSWKGDDSPVANGAEPAGQRRQRDREPEREERKEEEKLKTSQSSILDLADIFAPAPALPSTHCSADPWDIPGLRPNTEPSGSSWGPSADPWSPVPSGNALSRSQPWDLLPTLSSSEPWGRTPVLPSGPPIADPWAPSSPTRKLPSTGADPWGASMETSDTSALGGASPFDPFAKPLESTEPKESRDSAQALPTGKSPSTVELDPFGDSSPSCKQNGMKEPEALDLGVLGEALPQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNPFLTGLGVPSPTNPFGAGDQGRPTLNQMRTGSPALGLPPGGPVGAPVGSMTYSASLPLPLSSVPVGATLPASVSVFPQAGAFAPPPASLPQPLLPTSGPMGPLPPQAGTNPFL", "length": 636 }, "evidence": [ { "id": "A0A8V1APK7", "url": "https://omabrowser.org/oma/group/A0A8V1APK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H201-1", "protein_name": "Epsin-3", "gene_name": "EPN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQRDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSPIPSGTVLSRSQPWDLTPMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGGASTFDPFAKPPESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDALDLGILGEALTQPSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNPFLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLAGGPVGAPLGSMTYSASLPLPLSSVPAGLTLPASVSVFPQAGAFAPQPLLPTPSSAGPRPPPPQTGTNPFL", "length": 632 }, "evidence": [ { "id": "A0A8V1APK7", "url": "https://omabrowser.org/oma/group/A0A8V1APK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7" } ], "pmid": "" }, { "name": "clathrin vesicle coat", "id": "GO:0030125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 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"database": "Ensembl Peptide", "id": "ENSGALP00010044344.1", "url": "https://www.ensembl.org/id/ENSGALP00010044344.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chemokine activity", "id": 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"Protein" ] }, { "id": "A0A8V1AMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLV3", "url": "https://www.uniprot.org/uniprotkb/F1NLV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLV3-1", "url": "https://www.uniprot.org/uniprotkb/F1NLV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRQGSSDDIEDVSLFDADDEVSRRSKKSKIRHPVASFFHLFFRVSAIVVYLLCELLTSSFIACMVTIILLLSCDFWAVKNVTGRLMVGLRWWNQVDDDGRSHWKFESRKVSAQGHKTSSESESRIFWLGLITCPIIWVIFAFSALFSFKVKWLAVVMMGVVLQGANLYGYIRCKVGSRKNLTSMATSYLGKQFLRQCHGVVP", "length": 203, "header": "tr|A0A8V1AMG5-1|A0A8V1AMG5_CHICK Isoform 1 of Golgi apparatus membrane protein TVP23 homolog OS=Gallus gallus OX=9031 GN=TVP23B PE=1 SV=1 CANONICAL=A0A8V1AMG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG5/entry#A0A8V1AFM4-1", "sequence": { "sequence": "MLRQGSSDDIEDVSLFDADDEVSRRSKKSKIRHPVASFFHLFFRVSAIVVYLLCELLTSSFIACMVTIILLLSCDFWAVKNVTGRLMVGLRWWNQVDDDGRSHWKFESRKVSAQGHKTSSESESRIFWLGLITCPIIWVIFAFSALFSFKVKWLAVVMMGVVLQGANLYGYIRCKVGSRKNLTSMATSYLGKQFLRQLPAALGTTGHCSTSRLSFNYSLSQVS", "length": 223, "header": "tr|A0A8V1AFM4-1|A0A8V1AFM4_CHICK Computationally mapped isoform of Golgi apparatus membrane protein TVP23 homolog OS=Gallus gallus OX=9031 GN=TVP23B PE=1 SV=1 CANONICAL=A0A8V1AMG5-1" }, "locus": { "chromosome": "18", "start_pos": 2880326, "end_pos": 2875323, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072351.1", "url": "https://www.ensembl.org/id/ENSGALT00010072351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044818.1", "url": "https://www.ensembl.org/id/ENSGALP00010044818.1" } ] } }, { "isoform_ac": "A0A8V1AMG5-1", "url": 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Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZVP7-1", "protein_name": "Golgi apparatus membrane protein TVP23 homolog", "gene_name": "Tvp23b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ISKQDSNDDTEDVSLFDAEEETTSRPRKSRIRHPVASFFHLFFRVSAVVVYLLCELLSSSFIACMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGKSHWVFESRKSTPQDSKTISEAESRIFWLGLIACPVLWVIFAFSALFSFRVKWLAVVIMGVVLQGANLYGYVRCKVGSKKNLTSMATSYLGKQFLRQNAGDGQTS", "length": 205 }, "evidence": [ { "id": "A0A8V1AMG5", "url": "https://omabrowser.org/oma/group/A0A8V1AMG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86I95-1", "protein_name": "Uncharacterized Golgi apparatus membrane protein-like protein 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMKYSPFQDEPSSDNNNNGQNSESQPQSNAPKHPISVFFHLFFKIVAVAIFILSSFVNIGFVLTFIIVTLSSAFDFWVTKNVTGRKLVGLRWWNQIKEDGTNNWVFESVQDKSQVNPAESLMFWVPVLAFTAAWFVFSIISLFGLSFLWLVVEIVCFLLAGANLLGYIKCAKDARKKVKGMAQSYIVGTIVNQAINRV", "length": 198 }, "evidence": [ { "id": "A0A8V1AMG5", "url": "https://omabrowser.org/oma/group/A0A8V1AMG5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IQC1-1", "protein_name": "Uncharacterized Golgi apparatus membrane protein-like protein CG5021", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASATVRNVPLLDDDTIPFGEEDEMRDPSRAGQKYTHPYVTFFHLFFRGAAILIYMFCGWFSDSFITSFVFVVLFLSADFWTVKNISGRLLVGLRWWNYVDDDGVSHWVFESKNSESYQSRVNKNEQRIFWLGLILCPVFWGLFFLFALFGLKFKWLLLVMIAIALNAANLYGYVKCNYGANKDLNSAATDFVKTQFFKNAVDIMTRPSGAPPPTNVRPTGVV", "length": 223 }, "evidence": [ { "id": "A0A8V1AMG5", "url": "https://omabrowser.org/oma/group/A0A8V1AMG5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q96ET8-1", "protein_name": "Golgi apparatus membrane protein TVP23 homolog C", "gene_name": "TVP23C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQQDSNDDTEDVSLFDAEEETTNRPRKAKIRHPVASFFHLFFRVSAIIVCLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGKSHWVFESRKESSQENKTVSEAESRIFWLGLIACSVLWVIFAFSALFSFTVKWLRRSRHIAQTGLKVLGSRDPPASAFQSAGITGVSRCPGHPSRKFHQVDINSFTRITDRALYWKPAPRLSSPPLRAAPGNCQQMAPARLFLSLRLWAWRGGGESPNSRGTGEPGPKFHLASGMH", "length": 276 }, "evidence": [ { "id": "A0A8V1AMG5", "url": "https://omabrowser.org/oma/group/A0A8V1AMG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8T4-1", "protein_name": "Golgi apparatus membrane protein TVP23 homolog B", "gene_name": "Tvp23b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALG4-1", "uniprot_ac": "A0A8V1ALG4", "uniprot_id": "A0A8V1ALG4_CHICK", "mass": { "chemical_mass": 56567.0, "monoisotopic_mass": 56567.0 }, "refseq": {}, "gene_names": [ { "name": "ZBTB34", "type": "recommended", "evidence": [ { "id": "A0A8V1ALG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain containing 34", "type": "synonym", "evidence": [ { "id": "A0A8V1ALG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB34", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4", "locus": { "chromosome": "17", "start_pos": 10877691, "end_pos": 10852388, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028669", "url": "https://www.ensembl.org/id/ENSGALG00010028669" } ] } } ], "crossref": [ { "id": "A0A8V1ALG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023407", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023407", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417090", "url": "https://www.ncbi.nlm.nih.gov/gene/417090", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417090", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417090", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVSNTGY", "url": "https://omabrowser.org/oma/group/MVSNTGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALG4", "url": "https://www.orthodb.org/?gene=A0A8V1ALG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZL6", "url": "https://www.orthodb.org/?gene=F1NZL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZL6", "url": "https://www.uniprot.org/uniprotkb/F1NZL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZL6-1", "url": "https://www.uniprot.org/uniprotkb/F1NZL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFHFTSVEMDSSSFIQFDVPEYSNTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENSENRNGVKDSSYFANPIEISPPYCSQVRQSTASSDLRMETTPGKTLRSRLQEEGHSDRGSSGSISEYEVQIEGDHEQGDLIVRESQIAEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHVYSFTHASSQATGVSETFGNLSNSSPSRSMLSCFRGGRARQKRISAGHLHTDVQGLVQGTDGDSMVSNTGYENSPRERNARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVTEVRNRVESPDRTEAFVEQKVDNDASASETMDSSMEIHAMSNTSD", "length": 508, "header": "tr|A0A8V1ALG4-1|A0A8V1ALG4_CHICK Isoform 1 of Zinc finger and BTB domain containing 34 OS=Gallus gallus OX=9031 GN=ZBTB34 PE=4 SV=1 CANONICAL=A0A8V1ALG4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4/entry#A0A8V1ALG4-1", "sequence": { "sequence": "MRFHFTSVEMDSSSFIQFDVPEYSNTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENSENRNGVKDSSYFANPIEISPPYCSQVRQSTASSDLRMETTPGKTLRSRLQEEGHSDRGSSGSISEYEVQIEGDHEQGDLIVRESQIAEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHVYSFTHASSQATGVSETFGNLSNSSPSRSMLSCFRGGRARQKRISAGHLHTDVQGLVQGTDGDSMVSNTGYENSPRERNARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVTEVRNRVESPDRTEAFVEQKVDNDASASETMDSSMEIHAMSNTSD", "length": 508, "header": "tr|A0A8V1ALG4-1|A0A8V1ALG4_CHICK Isoform 1 of Zinc finger and BTB domain containing 34 OS=Gallus gallus OX=9031 GN=ZBTB34 PE=4 SV=1 CANONICAL=A0A8V1ALG4-1" }, "locus": { "chromosome": "17", "start_pos": 10872042, "end_pos": 10868171, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069403.1", "url": "https://www.ensembl.org/id/ENSGALT00010069403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042763.1", "url": "https://www.ensembl.org/id/ENSGALP00010042763.1" } ] } }, { "isoform_ac": "F1NZL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4/entry#F1NZL6-1", "sequence": { "sequence": "MDSSSFIQFDVPEYSNTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENSENRNGVKDSSYFANPIEISPPYCSQVRQSTASSDLRMETTPGKTLRSRLQEEGHSDRGSSGSISEYEVQIEGDHEQGDLIVRESQIAEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHVYSFTHASSQATGVSETFGNLSNSSPSRSMLSCFRGGRARQKRISAGHLHTDVQGLVQGTDGDSMVSNTGYENSPRERNARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVTEVRNRVESPDRTEAFVEQKVDNDASASETMDSSMEIHAMSNTSD", "length": 499, "header": "tr|F1NZL6-1|A0A8V1ALG4_CHICK Computationally mapped isoform of Zinc finger and BTB domain containing 34 OS=Gallus gallus OX=9031 GN=ZBTB34 PE=4 SV=1 CANONICAL=A0A8V1ALG4-1" }, "locus": { "chromosome": "17", "start_pos": 10872042, "end_pos": 10870546, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069404.1", "url": "https://www.ensembl.org/id/ENSGALT00010069404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042764.1", "url": "https://www.ensembl.org/id/ENSGALP00010042764.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417090", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417090", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ATY4-1", "protein_name": "Zinc finger and BTB domain containing 34", "gene_name": "Zbtb34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESTLEECNSRLRFVSGEMDNSSFIQFDVPEHSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPSVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTIGAEENPESRNGVKDGSFFTNPVEISPPYCPQVRQPPVSSDLRMETTPNKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGAYGSVLQHAYPYSQTASQPSSVPEAFGGQTNSSPSRSMLSCFRGRGARQKRALSVHLHSDLQGVVQGSDSEAMMNNPGYESSPRERSARGYWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEVCGKCFPFQGTLNQHLRKNHPGVTEGRGRMESPERTDMYVEQKLESDASASEMALDSRLEMHTVSDAPD", "length": 518 }, "evidence": [ { "id": "A0A8V1ALG4", "url": "https://omabrowser.org/oma/group/A0A8V1ALG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0V1A3-1", "protein_name": "Zinc finger and BTB domain-containing protein 34", "gene_name": "zbtb34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDCGSLIEFDVPEFSNTVLNQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSSLGTMSGLSISVIKSPEVFEQLLAFCYTGRMALRLRDVISFLTAASFLQMQAVIDKCTQILEGIHSKISIPASGEIDPDNECTTSRAGRNGVKDRGIFVNPTEISPSHFSRQNHCMEGQSSGKGIAEEGQSDRGSSDSISEQEASMEVESEQVELIGKDGQVTDVHIKLEKTDRPSYSDSSSAGDDGYHTELVDGEQVLAVSVGSYMPVLSSVGYTYSALPSSCFVSLSSSSPSRSLLSSVRGGRARPKRPVPLPVDMLTQPKPGADEGEPPATTATFENDVRERSLRGQWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDNKPFHCQICGKCFPFQGTLNQHLRKKHMTSGTEINNHTDLLEEAPDGQRGEQEDISEGEAACGAAYPDDLSKKSPSEESGKCSPEEPPASKLLRGY", "length": 508 }, "evidence": [ { "id": "A0A8V1ALG4", "url": "https://omabrowser.org/oma/group/A0A8V1ALG4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LW70-1", "protein_name": "Zinc finger and BTB domain containing 34", "gene_name": "Zbtb34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSSFIQFDVPEHSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPSVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTIGAEETPESRNGVKDGSFFTSPVEISPPYCPQVRQPPVSSDLRMETTPNKALRSRLQEEGHSDRGSSGSVSEYEVQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGTYGSVLQHAYPYSQAASQPSSVPEAFGGQTNSSPSRSMLSCFRGRGARQKRALSVHLHSDLQGVVQGSDSEAMMNNPGYESSPRERSARGYWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEVCGKCFPFQGTLNQHLRKNHPGVTEGRGRMESPERTDVYGEQKLESDASASEMALDSRLEIHTVSDAPD", "length": 500 }, "evidence": [ { "id": "A0A8V1ALG4", "url": "https://omabrowser.org/oma/group/A0A8V1ALG4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MIV1-1", "protein_name": "Zinc finger and BTB domain containing 34", "gene_name": "ZBTB34", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEETPESRNGVKDSSFFANPVEISPPYCSQVRQPTTSSDLRMETTPSKALRSSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLGRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYCQAASQPAGGVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAVVSNPGFESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRMESPERTDVYAEQKLENDASASEMALDSRMEIHTVSDAPD", "length": 506 }, "evidence": [ { "id": "A0A8V1ALG4", "url": "https://omabrowser.org/oma/group/A0A8V1ALG4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NCN2-1", "protein_name": "Zinc finger and BTB domain-containing protein 34", "gene_name": "ZBTB34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD", "length": 500 }, "evidence": [ { "id": "A0A8V1ALG4", "url": "https://omabrowser.org/oma/group/A0A8V1ALG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 105, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ALG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 381, "end_pos": 408, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BYD2-1", "uniprot_ac": "E1BYD2", "uniprot_id": "E1BYD2_CHICK", "mass": { "chemical_mass": 36950.0, "monoisotopic_mass": 36950.0 }, "refseq": { "ac": "NP_001264321", "name": "nucleoporin Nup37", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264321" }, "gene_names": [ { "name": "NUP37", "type": "recommended", "evidence": [ { "id": "E1BYD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYD2" } ] }, { "name": "NUP37", "type": "synonym", "evidence": [ { "id": "NP_001264321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264321" } ] } ], "protein_names": [ { "name": "Nucleoporin Nup37", "type": "recommended", "evidence": [ { "id": "E1BYD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYD2/entry#names_and_taxonomy" } ] }, { "name": "Nup107-160 subcomplex subunit Nup37", "type": "synonym", "evidence": [ { "id": "E1BYD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYD2/entry#names_and_taxonomy" } ] }, { "name": "nucleoporin 37kDa", "type": "synonym", "evidence": [ { "id": "NP_001264321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264321" } ] }, { "name": "nucleoporin Nup37", "type": "synonym", "evidence": [ { "id": "NP_001264321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264321" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01120335.1, HAEK01000181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Apr 6, 2013 this sequence version replaced XP_416326.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264321" } ] }, { "annotation": "Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. 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"tr|A0A8V0YCU0-1|E1BYD2_CHICK Computationally mapped isoform of Nucleoporin Nup37 OS=Gallus gallus OX=9031 GN=NUP37 PE=1 SV=1 CANONICAL=E1BYD2-1" }, "locus": { "chromosome": "1", "start_pos": 55489115, "end_pos": 55465415, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027181.1", "url": "https://www.ensembl.org/id/ENSGALT00010027181.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015475.1", "url": "https://www.ensembl.org/id/ENSGALP00010015475.1" } ] } }, { "isoform_ac": "A0A8V0YHH1-1", "url": "https://www.uniprot.org/uniprotkb/E1BYD2/entry#A0A8V0YHH1-1", "sequence": { "sequence": "MKQDSLRNAAYTVDCEDYVHVIKFNPFDSGDACSLIAYGGNNYVVVGTCRFQEEDAEVEGIQYKTLRTFHHGIRVDAIAWSPETRLDALPPQIRFCTAASDRKLRLFTSDLQDKNEYKTFDGHSDYVNDLVFAPREGQEVASVSDDHTCRVWDLEGNEKAHFVLRSPGMSVCWHPEEAFKLMVAEKNGTIRFYDLITHQAILSLECEQTPLMSADWCLKNTLRIGAVAGSDWLIWDITRSRYFLHVGEYFLLKQHVKSCGYFANITFNCSMYCITYSVINKYFIRNYKITTGHFLPYFFMFTSMC", "length": 305, "header": "tr|A0A8V0YHH1-1|E1BYD2_CHICK Computationally mapped isoform of Nucleoporin Nup37 OS=Gallus gallus OX=9031 GN=NUP37 PE=1 SV=1 CANONICAL=E1BYD2-1" }, "locus": { "chromosome": "1", "start_pos": 55485619, "end_pos": 55465415, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027171.1", "url": "https://www.ensembl.org/id/ENSGALT00010027171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015468.1", "url": "https://www.ensembl.org/id/ENSGALP00010015468.1" } ] } }, { "isoform_ac": "E1BYD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BYD2/entry#E1BYD2-1", "sequence": { "sequence": "MKQDSLRNAAYTVDCEDYVHVIKFNPFDSGDACSLIAYGGNNYVVVGTCRFQEEDAEVEGIQYKTLRTFHHGIRVDAIAWSPETRLDALPPQIRFCTAASDRKLRLFTSDLQDKNEYKTFDGHSDYVNDLVFAPREGQEVASVSDDHTCRVWDLEGNEKAHFVLRSPGMSVCWHPEEAFKLMVAEKNGTIRFYDLITHQAILSLECEQTPLMSADWCLKNTLRIGAVAGSDWLIWDITRSSYPQDKRPVHVDRARLFRWSRVNENLFATIGYPGKATTQLLVHHLGHPQPILTGTAAVGSGLTWHRTLPLCAVGGDHKIFFWVTEM", "length": 326, "header": "tr|E1BYD2-1|E1BYD2_CHICK Isoform 1 of 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"description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization 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"MKQDATRNAAYTVDCEDYVHVVEFNPFESGDSGNLIAYGGSNYVVIGMCTFQEEEADIEGIQYKTLRTFHHGVRVDGIAWSPETKLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHSDFINDLVFHPKEGHEIASVSDDHTCRIWSLEGKQTAHFLLHSPGMSVCWHPEETFKLMVAEKNGMIRFYDLMAQQAILSLQSEQTPLMSAHWCLKNTFKVGAVAGNDWIIWDITRSSYPQETRPVHMDRAHLFRWSAISENLFATTGYPGKMASQFQIHHLGHSQPILTGSVAVGSGLSWHRTLPLCAVGGDHKLLFWVTEI", "length": 326 }, "evidence": [ { "id": "E1BYD2", "url": "https://omabrowser.org/oma/group/E1BYD2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V6M8-1", "protein_name": "Nucleoporin Nup37", "gene_name": "Nup37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKQDVTRNAAYTVDCEDYVHVVEFNPFESGESGNLIAYGGSNYVVVGMCMFQEEGTDTEGIQYKTLRTFHHGVRVDGIAWSPETKLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHSDFINDLVFHPREGQEIASVSDDHTCRIWSLEGKQTAHFLLHSPGMSVCWHPEETFKLMVAEKNGTIRFYDLMAQQAILSLQSEQTPLMSAHWCLKNTFKVGAVAGNDWIIWDITRSSYPQETRPVHMDRAHSFRWSAISENLFATTGYPGKMSSQFQIHHLGHSQFRDSKEPCAVIAFLYIHLTEEHLRCLSELRPPLLHCTLSPL", "length": 330 }, "evidence": [ { "id": "E1BYD2", "url": "https://omabrowser.org/oma/group/E1BYD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKQDASRNAAYTVDCEDYVHVVEFNPFENGDSGNLIAYGGNNYVVIGTCTFQEEEADVEGIQYKTLRTFHHGVRVDGIAWSPETRLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHTDFINGLVFDPKEGQEIASVSDDHTCRIWNLEGVQTAHFVLHSPGMSVCWHPEETFKLMVAEKNGTIRFYDLLAQQAILSLESEQVPLMSAHWCLKNTFKVGAVAGNDWLIWDITRSSYPQNKRPVHMDRACLFRWSTISENLFATTGYPGKMASQFQIHHLGHPQPILMGSVAVGSGLSWHRTLPLCVIGGDHKLLFWVTEV", 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"UniProtKB", "id": "E1BYD2", "url": "https://www.uniprot.org/uniprotkb/E1BYD2" } ], "pmid": "" }, { "name": "mRNA transport", "id": "GO:0051028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051028", "evidence": [ { "database": "UniProtKB", "id": "E1BYD2", "url": "https://www.uniprot.org/uniprotkb/E1BYD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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} ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTS5-1", "uniprot_ac": "E1BTS5", "uniprot_id": "E1BTS5_CHICK", "mass": { "chemical_mass": 67664.0, "monoisotopic_mass": 67664.0 }, "refseq": { "ac": "XP_015145753", "name": "syntaxin-binding protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145753" }, "gene_names": [ { "name": "STXBP3", "type": "recommended", "evidence": [ { "id": "E1BTS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ] }, { "name": "STXBP3", "type": "synonym", "evidence": [ { "id": "XP_015145753", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145753" } ] } ], "protein_names": [ { "name": "Syntaxin binding protein 3", "type": "synonym", "evidence": [ { "id": "E1BTS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTS5/entry#names_and_taxonomy" } ] }, { "name": "syntaxin-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015145753", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145753" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145753", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145753" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STXBP3", "url": "https://www.uniprot.org/uniprotkb/E1BTS5", "locus": { "chromosome": "8", "start_pos": 1308967, "end_pos": 1280967, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012066", "url": "https://www.ensembl.org/id/ENSGALG00010012066" } ] } } ], "crossref": [ { "id": "E1BTS5", "url": "https://alphafold.ebi.ac.uk/entry/E1BTS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002001", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002001", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424341", "url": "https://www.ncbi.nlm.nih.gov/gene/424341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LSTCVRM", "url": "https://omabrowser.org/oma/group/LSTCVRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NW10", "url": "https://www.orthodb.org/?gene=A0A1D5NW10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7M8", "url": "https://www.orthodb.org/?gene=A0A8V0Y7M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCK6", "url": "https://www.orthodb.org/?gene=A0A8V0YCK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCL4", "url": "https://www.orthodb.org/?gene=A0A8V0YCL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDV4", "url": "https://www.orthodb.org/?gene=A0A8V0YDV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTS5", "url": "https://www.orthodb.org/?gene=E1BTS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114516", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114516", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015145753", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145753", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NW10", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NW10-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NW10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y7M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTS5-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPTARGLKSLVWQKLKSAVFDDCRKEDEWKVILLDDYTTKLLSLCCKMTDLLAEGITVVENVYKNREPVPHMKAIYFITPTKKSVDGLIDDFISKSSSRYKAAYVYFTDTCPDNLFNKIKSSCARSIRRCKEISISFFPYESQVFTLNVPDAFYCCYSPTLENSKDKDAVMEAMAEQIVTLCATLEENPGVRCKSTPSDNASRLAQLVEKKLENYYKTDEQSQIKAKTHSQLIIIDRGFDPVSTVLHELTFQAMAYDLLPIENETYKYKADGKDKEAILEEDDELWVKIRHKHIADVIEEISQLLKEVSSKKKAAEGKLTLSGLAHLMKKMPQYRKEITRQVVHLNIAEDCMSKFKANIERLCKTEQDLALGTDAEGQKVKDTMRVLLPVLLNKSHDSYDKIRAILLYIFSTNGTTEENLDKLIQNVQIESDSDMIRNWEYLHVPITNSSAVQQQKQPRRDRSSEETFQLSRWTPLIKDVMEDAIENKLDSKEWPYCSQCPPTWNGSGIVSARQKPKGSYQDERRSNARLIIFVIGGITYSEMRSAYEVSQTYKSCEVIVGSTHILTPRRLLDEVKSLNKPKDTVCIKDE", "length": 591, "header": "tr|E1BTS5-1|E1BTS5_CHICK Isoform 1 of Syntaxin binding protein 3 OS=Gallus gallus OX=9031 GN=STXBP3 PE=1 SV=4 CANONICAL=E1BTS5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NW10-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS5/entry#A0A1D5NW10-1", "sequence": { "sequence": "MEVVENVYKNREPVPHMKAIYFITPTKKSVDGLIDDFISKSSSRYKAAYVYFTDTCPDNLFNKIKSSCARSIRRCKEISISFFPYESQVFTLNVPDAFYCCYSPTLENSKDKDAVMEAMAEQIVTLCATLEENPGVRCKSTPSDNASRLAQLVEKKLENYYKTDEQSQIKAKTHSQLIIIDRGFDPVSTVLHELTFQAMAYDLLPIENETYKYKADGKDKEAILEEDDELWVKIRHKHIADVIEEISQLLKEVSSKKKAAEGKLTLSGLAHLMKKMPQYRKEITRQVVHLNIAEDCMSKFKANIERLCKTEQDLALGTDAEGQKVKDTMRVLLPVLLNKSHDSYDKIRAILLYIFSTNGTTEENLDKLIQNVQIESDSDMIRNWEYLHVPITNSSAVQQQKQPRRDRSSEETFQLSRWTPLIKDVMEDAIENKLDSKEWPYCSQCPPTWNGSGIVSARQKPKGSYQDERRSNARLIIFVIGGITYSEMRSAYEVSQTYKSCEVIVGSTHILTPRRLLDEVKSLNKPKDTVCIKDE", "length": 535, "header": "tr|A0A1D5NW10-1|A0A1D5NW10_CHICK Computationally mapped isoform of Syntaxin binding protein 3 OS=Gallus gallus OX=9031 GN=STXBP3 PE=1 SV=2 CANONICAL=E1BTS5-1" }, "locus": { "chromosome": "8", "start_pos": 1305674, "end_pos": 1284418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028913.1", "url": "https://www.ensembl.org/id/ENSGALT00010028913.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016672.1", "url": "https://www.ensembl.org/id/ENSGALP00010016672.1" } ] } }, { "isoform_ac": "A0A8V0Y7M8-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS5/entry#A0A8V0Y7M8-1", "sequence": { "sequence": "MRNRNQRYKVILLDDYTTKLLSLCCKMTDLLAEGITVVENVYKNREPVPHMKAIYFITPTKKSVDGLIDDFISKSSSRYKAAYVYFTDTCPDNLFNKIKSSCARSIRRCKEISISFFPYESQVFTLNVPDAFYCCYSPTLENSKDKDAVMEAMAEQIVTLCATLEENPGVRCKSTPSDNASRLAQLVEKKLENYYKTDEQSQIKAKTHSQLIIIDRGFDPVSTVLHELTFQAMAYDLLPIENETYKYKADGKDKEAILEEDDELWVKIRHKHIADVIEYVFELMSSIVSLQLTLSGLAHLMKKMPQYRKEITRQVVHLNIAEDCMSKFKANIERLCKTEQDLALGTDAEGQKVKDTMRVLLPVLLNKSHDSYDKIRAILLYIFSTNGTTEENLDKLIQNVQIESDSDMIRNWEYLHVPITNSSAVQQQKQPRRDRSSEETFQLSRWTPLIKDVMEDAIENKLDSKEWPYCSQCPPTWNGSGIVSARQKPKGSYQDERRSNARLIIFVIGGITYSEMRSAYEVSQTYKSCEVIVGSTHILTPRRLLDEVKSLNKPKDTVCIKDE", "length": 563, "header": "tr|A0A8V0Y7M8-1|E1BTS5_CHICK Computationally mapped isoform of Syntaxin binding protein 3 OS=Gallus gallus OX=9031 GN=STXBP3 PE=1 SV=1 CANONICAL=E1BTS5-1" }, "locus": { "chromosome": "8", "start_pos": 1305674, "end_pos": 1284604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028912.1", "url": "https://www.ensembl.org/id/ENSGALT00010028912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016671.1", "url": "https://www.ensembl.org/id/ENSGALP00010016671.1" } ] } }, { "isoform_ac": "A0A8V0YCK6-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS5/entry#A0A8V0YCK6-1", "sequence": { "sequence": "MCVFSYGCMKFLISKCSISCVVVVENVYKNREPVPHMKAIYFITPTKKSVDGLIDDFISKSSSRYKAAYVYFTDTCPDNLFNKIKSSCARSIRRCKEISISFFPYESQVFTLNVPDAFYCCYSPTLENSKDKDAVMEAMAEQIVTLCATLEENPGVRCKSTPSDNASRLAQLVEKKLENYYKTDEQSQIKAKTHSQLIIIDRGFDPVSTVLHELTFQAMAYDLLPIENETYKYKADGKDKEAILEEDDELWVKIRHKHIADVIEEISQLLKEVSSKKKAAEGKLTLSGLAHLMKKMPQYRKEITRQVVHLNIAEDCMSKFKANIERLCKTEQDLALGTDAEGQKVKDTMRVLLPVLLNKSHDSYDKIRAILLYIFSTNGTTEENLDKLIQNVQIESDSDMIRNWEYLHVPITNSSAVQQQKQPRRDRSSEETFQLSRWTPLIKDVMEDAIENKLDSKEWPYCSQCPPTWNGSGIVSARQKPKGSYQDERRSNARLIIFVIGGITYSEMRSAYEVSQTYKSCEVIVGSTHILTPRRLLDEVKSLNKPKDTVCIKDE", "length": 555, "header": "tr|A0A8V0YCK6-1|E1BTS5_CHICK Computationally mapped isoform of Syntaxin binding protein 3 OS=Gallus gallus OX=9031 GN=STXBP3 PE=1 SV=1 CANONICAL=E1BTS5-1" }, "locus": { "chromosome": "8", "start_pos": 1305674, "end_pos": 1287715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028906.1", "url": "https://www.ensembl.org/id/ENSGALT00010028906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016665.1", "url": "https://www.ensembl.org/id/ENSGALP00010016665.1" } ] } }, { "isoform_ac": "A0A8V0YCL4-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS5/entry#A0A8V0YCL4-1", "sequence": { "sequence": "MRNRNQRYKVILLDDYTTKLLSLCCKMTDLLAEGITVVENVYKNREPVPHMKAIYFITPTKKSVDGLIDDFISKSSSRYKAAYVYFTDTCPDNLFNKIKSSCARSIRRCKEISISFFPYESQVFTLNVPDAFYCCYSPTLENSKDKDAVMEAMAEQIVTLCATLEENPGVRCKSTPSDNASRLAQLVEKKLENYYKTDEQSQIKAKTHSQLIIIDRGFDPVSTVLHELTFQAMAYDLLPIENETYKYKADGKDKEAILEEDDELWVKIRHKHIADVIEEISQLLKEVSSKKKAAEGKLTLSGLAHLMKKMPQYRKEITRQVVHLNIAEDCMSKFKANIERLCKTEQDLALGTDAEGQKVKDTMRVLLPVLLNKSHDSYDKIRAILLYIFSTNGTTEENLDKLIQNVQIESDSDMIRNWEYLHVPITNSSAVQQQKQPRRDRSSEETFQLSRWTPLIKDVMEDAIENKLDSKEWPYCSQCPPTWNGSGIVSARQKPKGSYQDERRSNARLIIFVIGGITYSEMRSAYEVSQTYKSCEVIVGSTHILTPRRLLDEVKSLNKPKDTVCIKDE", "length": 569, "header": "tr|A0A8V0YCL4-1|E1BTS5_CHICK Computationally mapped isoform of Syntaxin binding protein 3 OS=Gallus gallus OX=9031 GN=STXBP3 PE=1 SV=1 CANONICAL=E1BTS5-1" }, "locus": { "chromosome": "8", "start_pos": 1305674, "end_pos": 1284604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028911.1", "url": "https://www.ensembl.org/id/ENSGALT00010028911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016670.1", "url": "https://www.ensembl.org/id/ENSGALP00010016670.1" } ] } }, { "isoform_ac": "A0A8V0YDV4-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS5/entry#A0A8V0YDV4-1", "sequence": { "sequence": "MSSSDALSEPRMSELRPAPGAGSRGSSVLHGLELVELKSAVFDDCRKEDEWKVILLDDYTTKLLSLCCKMTDLLAEGITVVENVYKNREPVPHMKAIYFITPTKKSVDGLIDDFISKSSSRYKAAYVYFTDTCPDNLFNKIKSSCARSIRRCKEISISFFPYESQVFTLNVPDAFYCCYSPTLENSKDKDAVMEAMAEQIVTLCATLEENPGVRCKSTPSDNASRLAQLVEKKLENYYKTDEQSQIKAKTHSQLIIIDRGFDPVSTVLHELTFQAMAYDLLPIENETYKYKADGKDKEAILEEDDELWVKIRHKHIADVIEEISQLLKEVSSKKKAAEGKLTLSGLAHLMKKMPQYRKEITRQVVHLNIAEDCMSKFKANIERLCKTEQDLALGTDAEGQKVKDTMRVLLPVLLNKSHDSYDKIRAILLYIFSTNGTTEENLDKLIQNVQIESDSDMIRNWEYLHVPITNSSAVQQQKQPRRDRSSEETFQLSRWTPLIKDVMEDAIENKLDSKEWPYCSQCPPTWNGSGIVSARQKPKGSYQDERRSNARLIIFVIGGITYSEMRSAYEVSQTYKSCEVIVGSTHILTPRRLLDEVKSLNKPKDTVCIKDE", "length": 612, "header": "tr|A0A8V0YDV4-1|E1BTS5_CHICK Computationally mapped isoform of Syntaxin binding protein 3 OS=Gallus gallus OX=9031 GN=STXBP3 PE=1 SV=1 CANONICAL=E1BTS5-1" }, "locus": { "chromosome": "8", "start_pos": 1305674, "end_pos": 1281158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028914.1", "url": "https://www.ensembl.org/id/ENSGALT00010028914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016673.1", "url": "https://www.ensembl.org/id/ENSGALP00010016673.1" } ] } }, { "isoform_ac": "E1BTS5-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS5/entry#E1BTS5-1", "sequence": { "sequence": "MAPTARGLKSLVWQKLKSAVFDDCRKEDEWKVILLDDYTTKLLSLCCKMTDLLAEGITVVENVYKNREPVPHMKAIYFITPTKKSVDGLIDDFISKSSSRYKAAYVYFTDTCPDNLFNKIKSSCARSIRRCKEISISFFPYESQVFTLNVPDAFYCCYSPTLENSKDKDAVMEAMAEQIVTLCATLEENPGVRCKSTPSDNASRLAQLVEKKLENYYKTDEQSQIKAKTHSQLIIIDRGFDPVSTVLHELTFQAMAYDLLPIENETYKYKADGKDKEAILEEDDELWVKIRHKHIADVIEEISQLLKEVSSKKKAAEGKLTLSGLAHLMKKMPQYRKEITRQVVHLNIAEDCMSKFKANIERLCKTEQDLALGTDAEGQKVKDTMRVLLPVLLNKSHDSYDKIRAILLYIFSTNGTTEENLDKLIQNVQIESDSDMIRNWEYLHVPITNSSAVQQQKQPRRDRSSEETFQLSRWTPLIKDVMEDAIENKLDSKEWPYCSQCPPTWNGSGIVSARQKPKGSYQDERRSNARLIIFVIGGITYSEMRSAYEVSQTYKSCEVIVGSTHILTPRRLLDEVKSLNKPKDTVCIKDE", "length": 591, "header": "tr|E1BTS5-1|E1BTS5_CHICK Isoform 1 of Syntaxin binding protein 3 OS=Gallus gallus OX=9031 GN=STXBP3 PE=1 SV=4 CANONICAL=E1BTS5-1" }, "locus": { "chromosome": "8", "start_pos": 1305674, "end_pos": 1281898, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028917.1", "url": "https://www.ensembl.org/id/ENSGALT00010028917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016676.1", "url": "https://www.ensembl.org/id/ENSGALP00010016676.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-114516", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114516", "resource": "Reactome", "description": "Disinhibition of SNARE formation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IK27-1", "protein_name": "Syntaxin-binding protein 3", "gene_name": "Stxbp3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPPVTERGLKSVVWRKIKTAVFDDCRKEGEWKIMLLDEFTTKLLSSCCKMTDLLEEGITVIENIYKNREPVRQMKALYFISPTSKSVDCFLRDFGSKRENKYKAAYIYFTDFCPDSLFNKIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPSNASRKEAVMEAMAEQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKMDEKGLVKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKYRTDGKDKEAVLEEDDDLWVRVRHRHIALVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQMTKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQRVKDSMLVLLPVLLNKNHDNCDKIRAVLLYIFGINGTTEENLDRLIHNVKIEDDSDMIRNWSHLGVPIVPPSQQAKPVRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSRCPAVWNGSGAVSARQKPRANYLELDRKNGSRLIIFVIGGITYSEMRCAYEVSQAHKSCEVIIGSTHILTPRKLLDDIKMLNKSKDKVSFLKEE", "length": 593 }, "evidence": [ { "id": "E1BTS5", "url": "https://omabrowser.org/oma/group/E1BTS5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O00186-1", "protein_name": "Syntaxin-binding protein 3", "gene_name": "STXBP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPVAERGLKSVVWQKIKATVFDDCKKEGEWKIMLLDEFTTKLLASCCKMTDLLEEGITVVENIYKNREPVRQMKALYFITPTSKSVDCFLHDFASKSENKYKAAYIYFTDFCPDNLFNKIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPGNAKGKDAIMETMADQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKSLIKGKTHSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAILEEEDDLWVRIRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQITKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQKVKDSMRVLLPVLLNKNHDNCDKIRAILLYIFSINGTTEENLDRLIQNVKIENESDMIRNWSYLGVPIVPQSQQGKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSQCPAVWNGSGAVSARQKPRANYLEDRKNGSKLIVFVIGGITYSEVRCAYEVSQAHKSCEVIIGSTHVLTPKKLLDDIKMLNKPKDKVSLIKDE", "length": 592 }, "evidence": [ { "id": "E1BTS5", "url": "https://omabrowser.org/oma/group/E1BTS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60770-1", "protein_name": "Syntaxin-binding protein 3", "gene_name": "Stxbp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPPVSERGLKSVVWRKIKTAVFDDCRKEGEWKIMLLDEFTTKLLSSCCKMTDLLEEGITVIENIYKNREPVRQMKALYFISPTPKSVDCFLRDFGSKSEKKYKAAYIYFTDFCPDSLFNKIKASCSKSIRRCKEINISFIPQESQVYTLDVPDAFYYCYSPDPSNASRKEVVMEAMAEQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDEKGLIKGKTQSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIENDTYKYKTDGKEKEAVLEEDDDLWVRVRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQISKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQRVKDSMLVLLPVLLNKNHDNCDKIRAVLLYIFGINGTTEENLDRLIHNVKIEDDSDMIRNWSHLGVPIVPPSQQAKPLRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSRCPAVWNGSGAVSARQKPRTNYLELDRKNGSRLIIFVIGGITYSEMRCAYEVSQAHKSCEVIIGSTHILTPRKLLDDIKMLNKSKDKVSFKDE", "length": 592 }, "evidence": [ { "id": "E1BTS5", "url": "https://omabrowser.org/oma/group/E1BTS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99PV2-1", "protein_name": "Syntaxin binding protein 3", "gene_name": "Stxbp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPPVTERGLKSVVWRKIKTTVFDDCRKEGEWKIMLLDDFTTRLLSSCCKMTDLLEEGVTVIENIYKNREPVRQMKALYFISPTPKSVDCFLRDFGSKSEKKYKAAYIYFTDFCPDSLFNKIKASCSKSIRRCKEINISFIPHESQVYTLDVPDAFYYCYSPDPSNAGRKEAVMEAMAEQIVTVCATLDENPGVRYKSKPLDNASKLAQLVEKKLEDYYKIDENGLIKGKTQSQLLIIDRGFDPVSTVLHELTFQAMAYDLLPIEKDTYKYKTDGKEKEAVLEEDDDLWVRVRHRHIAVVLEEIPKLMKEISSTKKATEGKTSLSALTQLMKKMPHFRKQISKQVVHLNLAEDCMNKFKLNIEKLCKTEQDLALGTDAEGQRVKDSMLVLLPVLLNKNHDNCDKIRAVLLYIFGVNGTTEENLDRLIHNVKIEDDSDMIRNWSHLGVPIVPPSQQAKPPRKDRSAEETFQLSRWTPFIKDIMEDAIDNRLDSKEWPYCSRCPAVWNGSGAVSARQKPRTNYLELDRKNGSRLIIFVIGGITYSEMRCAYEVSQAHKSCEVIIGSTHILTPRKLLDDIKMLNKSKDKVSFLKDE", "length": 593 }, "evidence": [ { "id": "E1BTS5", "url": "https://omabrowser.org/oma/group/E1BTS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9C5P7-1", "protein_name": "Protein transport Sec1a", "gene_name": "SEC1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSFSDSESSSHGGGGGDYKFFRQISRDRLLHEMLGSTKTGDSKAWKILIMDRVTVKVMSQSCKMADITDQGISLVEELFKRREPMPGMDAIYFIQPSKENIVMFLSDMSGREPLYRKAFIFFSSTIPKELVNHIKSDSSVLPRIGALREMNMEYFPIDNQGFLTDHEQALETLYAEDAENSRHFHICLNIMATRIATVFASLKELPFVRYRAAKSTASRDLVPSKLAAAIWDCISKYKAIPNFPQTETCELLIVDRSVDQIAPIIHEWTYDAMCHDLLDMEGNKHVIEVPSKTGGPPEKKEIVLEDHDPVWLELRHTHIADASERLHEKMTNFASKNKAAQMRSRDGSELSTRDLQKIVQALPQYGEQVDKLSTHVELAGKINRIIRDTGLRDLGQLEQDLVFGDAGAKDVINFLRTNQDTNPENKLRLLMIYATVYPEKFEGDKGVKLMQLARLSPVDMKVISNMQLIAGSPENKAKSGSFSLKFDAGKTKQANRKDRSGEEETWQLFRFYPMIEELLEKLVKGDLSKSDYLCMNQSSHKEESEARTGSVRKSSAPTAVPERKATPHSMRSRRTATWARPHSSDDGYSSDSVLKSASTEFKKLGQRIFVFIIGGATRSELRVCHKLTSSLRREVVLGSTSFDDPPQYITKLKLLSEKDIQGAPAQPFKPQYW", "length": 673 }, "evidence": [ { "id": "E1BTS5", "url": "https://omabrowser.org/oma/group/E1BTS5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "specific granule", "id": "GO:0042581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042581", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "tertiary granule", "id": "GO:0070820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070820", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "platelet alpha granule", "id": "GO:0031091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031091", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "neutrophil degranulation", "id": "GO:0043312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043312", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "negative regulation of calcium ion-dependent exocytosis", "id": "GO:0045955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045955", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "platelet aggregation", "id": "GO:0070527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070527", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "presynaptic dense core vesicle exocytosis", "id": "GO:0099525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099525", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "vesicle docking involved in exocytosis", "id": "GO:0006904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006904", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin-1 binding", "id": "GO:0017075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017075", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" }, { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "E1BTS5", "url": "https://www.uniprot.org/uniprotkb/E1BTS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 506, "end_pos": 508 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTE8-1", "uniprot_ac": "E1BTE8", "uniprot_id": "E1BTE8_CHICK", "mass": { "chemical_mass": 13855.0, "monoisotopic_mass": 13855.0 }, "refseq": { "ac": "XP_422292", "name": "uncharacterized protein C1orf21 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422292" }, "gene_names": [ { "name": "C1orf21", "type": "recommended", "evidence": [ { "id": "E1BTE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE8" } ] }, { "name": "C1orf21", "type": "synonym", "evidence": [ { "id": "XP_422292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422292" } ] } ], "protein_names": [ { "name": "Chromosome 1 open reading frame 21", "type": "synonym", "evidence": [ { "id": "E1BTE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C1orf21 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_422292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422292" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422292" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTE8", "url": "https://www.uniprot.org/uniprotkb/E1BTE8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf21", "url": "https://www.uniprot.org/uniprotkb/E1BTE8", "locus": { "chromosome": "8", "start_pos": 7919423, "end_pos": 7833125, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011643", "url": "https://www.ensembl.org/id/ENSGALG00010011643" } ] } } ], "crossref": [ { "id": "E1BTE8", "url": "https://alphafold.ebi.ac.uk/entry/E1BTE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000020922", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000020922", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424449", "url": "https://www.ncbi.nlm.nih.gov/gene/424449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424449", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KSNVQHK", "url": "https://omabrowser.org/oma/group/KSNVQHK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14974:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14974:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422292", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YE53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YE58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YE58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTE8", "url": "https://www.uniprot.org/uniprotkb/E1BTE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTE8-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCASAKHVSTVQNEEETQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGGEDDQKIAARNQENLEKSASSNVRLKSNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDVT", "length": 121, "header": "tr|E1BTE8-1|E1BTE8_CHICK Isoform 1 of Chromosome 1 open reading frame 21 OS=Gallus gallus OX=9031 GN=C1orf21 PE=4 SV=1 CANONICAL=E1BTE8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YE53-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE8/entry#A0A8V0YE53-1", "sequence": { "sequence": "MAMQDQGEQKRSWMVHVEKEDEYRIKPVEEVKYMKNGGEDDQKIAARNQENLEKSASSNVRLKSNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDVT", "length": 110, "header": "tr|A0A8V0YE53-1|E1BTE8_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 21 OS=Gallus gallus OX=9031 GN=C1orf21 PE=4 SV=1 CANONICAL=E1BTE8-1" }, "locus": { "chromosome": "8", "start_pos": 7918703, "end_pos": 7870958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027846.1", "url": "https://www.ensembl.org/id/ENSGALT00010027846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015969.1", "url": "https://www.ensembl.org/id/ENSGALP00010015969.1" } ] } }, { "isoform_ac": "A0A8V0YE58-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE8/entry#A0A8V0YE58-1", "sequence": { "sequence": "MGCASAKHVSTVQNEEETQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGGEDDQKIAARNQENLEDLLGRESWNVQEKSASSNVRLKSNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDVT", "length": 133, "header": "tr|A0A8V0YE58-1|E1BTE8_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 21 OS=Gallus gallus OX=9031 GN=C1orf21 PE=4 SV=1 CANONICAL=E1BTE8-1" }, "locus": { "chromosome": "8", "start_pos": 7918703, "end_pos": 7868555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027853.1", "url": "https://www.ensembl.org/id/ENSGALT00010027853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015974.1", "url": "https://www.ensembl.org/id/ENSGALP00010015974.1" } ] } }, { "isoform_ac": "A0A8V0YIU1-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE8/entry#A0A8V0YIU1-1", "sequence": { "sequence": "MGMLCPRKEKPVIQVGVMLLASADEYRIKPVEEVKYMKNGGEDDQKIAARNQENLEKSASSNVRLKSNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDVT", "length": 113, "header": "tr|A0A8V0YIU1-1|E1BTE8_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 21 OS=Gallus gallus OX=9031 GN=C1orf21 PE=4 SV=1 CANONICAL=E1BTE8-1" }, "locus": { "chromosome": "8", "start_pos": 7918703, "end_pos": 7885805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027841.1", "url": "https://www.ensembl.org/id/ENSGALT00010027841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015967.1", "url": "https://www.ensembl.org/id/ENSGALP00010015967.1" } ] } }, { "isoform_ac": "A0A8V0YIU7-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE8/entry#A0A8V0YIU7-1", "sequence": { "sequence": "MGCASAKHVSTVQNEEETQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGGEDDQKIAARNQENLEKSASSNVRLKSNKEIPGLVHQPRAKFLWGGKVGSAATSVSYTYFSKGFEQVH", "length": 116, "header": "tr|A0A8V0YIU7-1|E1BTE8_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 21 OS=Gallus gallus OX=9031 GN=C1orf21 PE=4 SV=1 CANONICAL=E1BTE8-1" }, "locus": { "chromosome": "8", "start_pos": 7914977, "end_pos": 7868555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027851.1", "url": "https://www.ensembl.org/id/ENSGALT00010027851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015972.1", "url": "https://www.ensembl.org/id/ENSGALP00010015972.1" } ] } }, { "isoform_ac": "E1BTE8-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE8/entry#E1BTE8-1", "sequence": { "sequence": "MGCASAKHVSTVQNEEETQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGGEDDQKIAARNQENLEKSASSNVRLKSNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDVT", "length": 121, "header": "tr|E1BTE8-1|E1BTE8_CHICK Isoform 1 of Chromosome 1 open reading frame 21 OS=Gallus gallus OX=9031 GN=C1orf21 PE=4 SV=1 CANONICAL=E1BTE8-1" }, "locus": { "chromosome": "8", "start_pos": 7918703, "end_pos": 7868555, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027857.1", "url": "https://www.ensembl.org/id/ENSGALT00010027857.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015978.1", "url": "https://www.ensembl.org/id/ENSGALP00010015978.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424449", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MWW2-1", "protein_name": "Uncharacterized protein C1orf21 homolog", "gene_name": "C5H1orf21", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGCASAKHVATVQNEEESQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNTRLKTNKEIPGLVQQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDIT", "length": 121 }, "evidence": [ { "id": "E1BTE8", "url": "https://omabrowser.org/oma/group/E1BTE8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZU88-1", "protein_name": "Similar to human chromosome 1 open reading frame 21", "gene_name": "C13h1orf21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCASAKHVATVQNEEEAQKGKSYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNTRLKTNKEIPGFVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDIT", "length": 121 }, "evidence": [ { "id": "E1BTE8", "url": "https://omabrowser.org/oma/group/E1BTE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S3P0-1", "protein_name": "Chromosome 9 C1orf21 homolog", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCASAKHVATVQNEEEAQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNVRLKTNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDIT", "length": 121 }, "evidence": [ { "id": "E1BTE8", "url": "https://omabrowser.org/oma/group/E1BTE8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8K207-1", "protein_name": "Uncharacterized protein C1orf21 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCASAKHVATVQNEEEAQRGKSYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNTRLKTNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDIT", "length": 121 }, "evidence": [ { "id": "E1BTE8", "url": "https://omabrowser.org/oma/group/E1BTE8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H246-1", "protein_name": "Uncharacterized protein C1orf21", "gene_name": "C1orf21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCASAKHVATVQNEEEAQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNVRLKTNKEVPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDIT", "length": 121 }, "evidence": [ { "id": "E1BTE8", "url": "https://omabrowser.org/oma/group/E1BTE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSM6-1", "uniprot_ac": "E1BSM6", "uniprot_id": "E1BSM6_CHICK", "mass": { "chemical_mass": 25599.0, "monoisotopic_mass": 25599.0 }, "refseq": { "ac": "XP_004942521", "name": "von Willebrand factor C domain-containing protein 2-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942521" }, "gene_names": [ { "name": "VWC2L", "type": "recommended", "evidence": [ { "id": "E1BSM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSM6" } ] }, { "name": "VWC2L", "type": "synonym", "evidence": [ { "id": "XP_004942521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942521" } ] } ], "protein_names": [ { "name": "von Willebrand factor C domain containing 2 like", "type": "synonym", "evidence": [ { "id": "E1BSM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSM6/entry#names_and_taxonomy" } ] }, { "name": "von Willebrand factor C domain-containing protein 2-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004942521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942521" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942521" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSM6", "url": "https://www.uniprot.org/uniprotkb/E1BSM6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VWC2L", "url": "https://www.uniprot.org/uniprotkb/E1BSM6", "locus": { "chromosome": "7", "start_pos": 4242257, "end_pos": 4203375, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011894", "url": "https://www.ensembl.org/id/ENSGALG00010011894" } ] } } ], "crossref": [ { "id": "E1BSM6", "url": "https://alphafold.ebi.ac.uk/entry/E1BSM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003472", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003472", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428995", "url": "https://www.ncbi.nlm.nih.gov/gene/428995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428995", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428995", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PICKHGP", "url": "https://omabrowser.org/oma/group/PICKHGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBI6", "url": "https://www.orthodb.org/?gene=A0A8V0YBI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBJ2", "url": "https://www.orthodb.org/?gene=A0A8V0YBJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF24", "url": "https://www.orthodb.org/?gene=A0A8V0YF24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YF33", "url": "https://www.orthodb.org/?gene=A0A8V0YF33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSM6", "url": "https://www.orthodb.org/?gene=E1BSM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46252:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46252:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23331", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23331", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23333", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23333", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942521", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YF33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSM6", "url": "https://www.uniprot.org/uniprotkb/E1BSM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BSM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKLRRGMALHIHEAWILLFVIPGLVTPAAINHEDYPADEGDQTSSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQAL", "length": 229, "header": "tr|E1BSM6-1|E1BSM6_CHICK Isoform 1 of von Willebrand factor C domain containing 2 like OS=Gallus gallus OX=9031 GN=VWC2L PE=4 SV=2 CANONICAL=E1BSM6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBI6-1", "url": "https://www.uniprot.org/uniprotkb/E1BSM6/entry#A0A8V0YBI6-1", "sequence": { "sequence": "MEKLRRGMALHIHEAWILLFVIPGLVTPAAINHEDYPADEGDQTSSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKVPTASQEPPSSPRASR", "length": 153, "header": "tr|A0A8V0YBI6-1|E1BSM6_CHICK Computationally mapped isoform of von Willebrand factor C domain containing 2 like OS=Gallus gallus OX=9031 GN=VWC2L PE=4 SV=1 CANONICAL=E1BSM6-1" }, "locus": { "chromosome": "7", "start_pos": 4241037, "end_pos": 4206272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028438.1", "url": "https://www.ensembl.org/id/ENSGALT00010028438.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016311.1", "url": "https://www.ensembl.org/id/ENSGALP00010016311.1" } ] } }, { "isoform_ac": "A0A8V0YBJ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BSM6/entry#A0A8V0YBJ2-1", "sequence": { "sequence": "MEKLRRGMALHIHEAWILLFVIPGLVTPAAINHEDYPADEGDQTSSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKEVLKWPDFKVAVKNPSVKVYAIC", "length": 160, "header": "tr|A0A8V0YBJ2-1|E1BSM6_CHICK Computationally mapped isoform of von Willebrand factor C domain containing 2 like OS=Gallus gallus OX=9031 GN=VWC2L PE=4 SV=1 CANONICAL=E1BSM6-1" }, "locus": { "chromosome": "7", "start_pos": 4226870, "end_pos": 4206272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028443.1", "url": "https://www.ensembl.org/id/ENSGALT00010028443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016316.1", "url": "https://www.ensembl.org/id/ENSGALP00010016316.1" } ] } }, { "isoform_ac": "A0A8V0YF24-1", "url": "https://www.uniprot.org/uniprotkb/E1BSM6/entry#A0A8V0YF24-1", "sequence": { "sequence": "MEKLRRGMALHIHEAWILLFVIPGLVTPAAINHEDYPADEGDQTSSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKV", "length": 138, "header": "tr|A0A8V0YF24-1|E1BSM6_CHICK Computationally mapped isoform of von Willebrand factor C domain containing 2 like OS=Gallus gallus OX=9031 GN=VWC2L PE=4 SV=1 CANONICAL=E1BSM6-1" }, "locus": { "chromosome": "7", "start_pos": 4206685, "end_pos": 4206272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028437.1", "url": "https://www.ensembl.org/id/ENSGALT00010028437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016310.1", "url": "https://www.ensembl.org/id/ENSGALP00010016310.1" } ] } }, { "isoform_ac": "A0A8V0YF33-1", "url": "https://www.uniprot.org/uniprotkb/E1BSM6/entry#A0A8V0YF33-1", "sequence": { "sequence": "MEKLRRGMALHIHEAWILLFVIPGLVTPAAINHEDYPADEGDQTSSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFK", "length": 137, "header": "tr|A0A8V0YF33-1|E1BSM6_CHICK Computationally mapped isoform of von Willebrand factor C domain containing 2 like OS=Gallus gallus OX=9031 GN=VWC2L PE=4 SV=1 CANONICAL=E1BSM6-1" }, "locus": { "chromosome": "7", "start_pos": 4206682, "end_pos": 4206272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028447.1", "url": "https://www.ensembl.org/id/ENSGALT00010028447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016320.1", "url": "https://www.ensembl.org/id/ENSGALP00010016320.1" } ] } }, { "isoform_ac": "E1BSM6-1", "url": "https://www.uniprot.org/uniprotkb/E1BSM6/entry#E1BSM6-1", "sequence": { "sequence": "MEKLRRGMALHIHEAWILLFVIPGLVTPAAINHEDYPADEGDQTSSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQAL", "length": 229, "header": "tr|E1BSM6-1|E1BSM6_CHICK Isoform 1 of von Willebrand factor C domain containing 2 like OS=Gallus gallus OX=9031 GN=VWC2L PE=4 SV=2 CANONICAL=E1BSM6-1" }, "locus": { "chromosome": "7", "start_pos": 4241135, "end_pos": 4206272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028440.1", "url": "https://www.ensembl.org/id/ENSGALT00010028440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016313.1", "url": "https://www.ensembl.org/id/ENSGALP00010016313.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428995", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428995", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UQB5-1", "protein_name": "von Willebrand factor C domain containing 2 like", "gene_name": "VWC2L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQTSNNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQTV", "length": 222 }, "evidence": [ { "id": "E1BSM6", "url": "https://omabrowser.org/oma/group/E1BSM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MWJ4-1", "protein_name": "von Willebrand factor C domain-containing protein 2-like", "gene_name": "Vwc2l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQASSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPIYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQPV", "length": 222 }, "evidence": [ { "id": "E1BSM6", "url": "https://omabrowser.org/oma/group/E1BSM6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6AU98-1", "protein_name": "von Willebrand factor C domain containing 2 like", "gene_name": "Vwc2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALHIHEACILLLVIPGLVTPAAISHEDYPADEGDQASSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPIYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQTV", "length": 222 }, "evidence": [ { "id": "E1BSM6", "url": "https://omabrowser.org/oma/group/E1BSM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0UZC8-1", "protein_name": "von Willebrand factor C domain-containing protein 2-like", "gene_name": "vwc2l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGPFLPAICVVLLALNAAVSPASVGPEDYPAADEAERTANNDIIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCTEDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYRGKTYKILEEFKPSPCEWCRCEPNNEVHCVVADCAVPECVNPVYEPEQCCPICKNGPNCFAGTTIIPAGIEVKVDDCTICRCHSGDWWKPAQCLRRECLNGQATS", "length": 223 }, "evidence": [ { "id": "E1BSM6", "url": "https://omabrowser.org/oma/group/E1BSM6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B2RUY7-1", "protein_name": "von Willebrand factor C domain-containing protein 2-like", "gene_name": "VWC2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQTV", "length": 222 }, "evidence": [ { "id": "E1BSM6", "url": "https://omabrowser.org/oma/group/E1BSM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q505H4-1", "protein_name": "von Willebrand factor C domain-containing protein 2-like", "gene_name": "Vwc2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQASSNDNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPIYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDDCNICHCHNGDWWKPAQCSKRECQGKQTV", "length": 222 }, "evidence": [ { "id": "E1BSM6", "url": "https://omabrowser.org/oma/group/E1BSM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BSM6", "url": "https://www.uniprot.org/uniprotkb/E1BSM6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BSM6", "url": "https://www.uniprot.org/uniprotkb/E1BSM6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BSM6", "url": "https://www.uniprot.org/uniprotkb/E1BSM6" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "E1BSM6", "url": "https://www.uniprot.org/uniprotkb/E1BSM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "E1BSM6", "url": "https://www.uniprot.org/uniprotkb/E1BSM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 229, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSM6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BT07-1", "uniprot_ac": "E1BT07", "uniprot_id": "E1BT07_CHICK", "mass": { "chemical_mass": 14612.0, "monoisotopic_mass": 14612.0 }, "refseq": { "ac": "NP_001265078", "name": "protein chibby homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265078" }, "gene_names": [ { "name": "CBY1", "type": "recommended", "evidence": [ { "id": "E1BT07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT07" } ] }, { "name": "CBY1", "type": "synonym", "evidence": [ { "id": "NP_001265078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265078" } ] } ], "protein_names": [ { "name": "Chibby family member 1, beta catenin antagonist", "type": "synonym", "evidence": [ { "id": "E1BT07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT07/entry#names_and_taxonomy" } ] }, { "name": "chibby homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001265078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265078" } ] }, { "name": "protein chibby homolog 1", "type": "synonym", "evidence": [ { "id": "NP_001265078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265078" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX931504.2, BU376235.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On May 12, 2013 this sequence version replaced XP_001234193.1. Sequence Note: This RefSeq record was created with transcript data from different strains to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265078" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BT07", "url": "https://www.uniprot.org/uniprotkb/E1BT07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CBY1", "url": "https://www.uniprot.org/uniprotkb/E1BT07", "locus": { "chromosome": "1", "start_pos": 50886608, "end_pos": 50895597, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012792", "url": "https://www.ensembl.org/id/ENSGALG00010012792" } ] } } ], "crossref": [ { "id": "E1BT07", "url": "https://alphafold.ebi.ac.uk/entry/E1BT07", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012218", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012218", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771364", "url": "https://www.ncbi.nlm.nih.gov/gene/771364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028118", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028118", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771364", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771364", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IWMHSAR", "url": "https://omabrowser.org/oma/group/IWMHSAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFX5", "url": "https://www.orthodb.org/?gene=A0A8V0YFX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BT07", "url": "https://www.orthodb.org/?gene=E1BT07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21533:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21533:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3769402", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3769402", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001265078", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265078", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT07", "url": "https://www.uniprot.org/uniprotkb/E1BT07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT07-1", "url": "https://www.uniprot.org/uniprotkb/E1BT07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFGSTFSPKKTPPRKAASLSNLHLLDRSTREVELGLEYGTPTMNLTGQSLKFENGQWVAEIGSFTGDRREMQRLRKRNQQLEEENNLLRLKVDILLDMLSETTAESHLMEKELEELKSHTRRRK", "length": 126, "header": "tr|E1BT07-1|E1BT07_CHICK Isoform 1 of Chibby family member 1, beta catenin antagonist OS=Gallus gallus OX=9031 GN=CBY1 PE=4 SV=1 CANONICAL=E1BT07-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFX5-1", "url": "https://www.uniprot.org/uniprotkb/E1BT07/entry#A0A8V0YFX5-1", "sequence": { "sequence": "MPLFGSTFSPKKTPPRKAASLSNLHLLDRSTREVELGLEYGTPTMNLTGQSLKFENGQWVAGSAVRGGWACRGHGWLMALLVVSLFPPEIGSFTGDRREMQRLRKRNQQLEEENNLLRLKVDILLDMVSNEPLSALRGGSADVKGAGGHQRKRFLQWRVHSIPALPHCTRKNVVPKQTWGKGLTSSAPSAR", "length": 191, "header": "tr|A0A8V0YFX5-1|E1BT07_CHICK Computationally mapped isoform of Chibby family member 1, beta catenin antagonist OS=Gallus gallus OX=9031 GN=CBY1 PE=4 SV=1 CANONICAL=E1BT07-1" }, "locus": { "chromosome": "1", "start_pos": 50888554, "end_pos": 50887612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030677.1", "url": "https://www.ensembl.org/id/ENSGALT00010030677.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017787.1", "url": "https://www.ensembl.org/id/ENSGALP00010017787.1" } ] } }, { "isoform_ac": "E1BT07-1", "url": "https://www.uniprot.org/uniprotkb/E1BT07/entry#E1BT07-1", "sequence": { "sequence": "MPLFGSTFSPKKTPPRKAASLSNLHLLDRSTREVELGLEYGTPTMNLTGQSLKFENGQWVAEIGSFTGDRREMQRLRKRNQQLEEENNLLRLKVDILLDMLSETTAESHLMEKELEELKSHTRRRK", "length": 126, "header": "tr|E1BT07-1|E1BT07_CHICK Isoform 1 of Chibby family member 1, beta catenin antagonist OS=Gallus gallus OX=9031 GN=CBY1 PE=4 SV=1 CANONICAL=E1BT07-1" }, "locus": { "chromosome": "1", "start_pos": 50888554, "end_pos": 50886928, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030666.1", "url": "https://www.ensembl.org/id/ENSGALT00010030666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017781.1", "url": "https://www.ensembl.org/id/ENSGALP00010017781.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771364", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771364", "resource": "KEGG Pathway" }, { "id": "R-GGA-3769402", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3769402", "resource": "Reactome", "description": "Deactivation of the beta-catenin transactivating complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I2E3-1", "protein_name": "Protein chibby homolog 1", "gene_name": "Cby1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPLFGSIFSPKKTPPRKSASLSNLHSLDRSTRELELGLDYGTPTMNLAGQNLKFENGQWVADTVISGGVDRRETQRLRKRNQQLEEENNLLRLKVDILLDMLSETTAESHLKDKELDELKIINRRRK", "length": 127 }, "evidence": [ { "id": "E1BT07", "url": "https://omabrowser.org/oma/group/E1BT07/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B9A0M5-1", "protein_name": "Chibby, isoform E", "gene_name": "Cby", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLATFCCPSSISDSQPLPFKQLFAMPLFNKKFESKPIPVRQGRCNIGHPVATEDLDDFRQISLTLGNKELRFADGIWMHSTRKGDVDDMLRLNKKFRALEEENNMCNLKIEVMLDLLAEHATELSELKPKEK", "length": 133 }, "evidence": [ { "id": "E1BT07", "url": "https://omabrowser.org/oma/group/E1BT07/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8MJK1-1", "protein_name": "Protein chibby homolog 1", "gene_name": "CBY1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLFGSTFSPKKTPPRKSASLSNLHNLDRSTREVELGLDYGTPTMNLAGQSLKFENGQWIAETGISGGVDRREAQRLRRRNQQLEEENNLLRLKVDILLDMLSETTAESHLMEKELDELKSVSRRRK", "length": 127 }, "evidence": [ { "id": "E1BT07", "url": "https://omabrowser.org/oma/group/E1BT07/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D1C2-1", "protein_name": "Protein chibby homolog 1", "gene_name": "Cby1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLFGSIFSPKKTPPRKSASLSNLHSLDRSTRELELGLDYGTPTMNLAGQSLKFENGQWVADSVISGGVDRRETQRLRKRNQQLEEENNLLRLKVDILLDMLSETTAESHLKDKELDELKVTNRRRK", "length": 127 }, "evidence": [ { "id": "E1BT07", "url": "https://omabrowser.org/oma/group/E1BT07/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3M2-1", "protein_name": "Protein chibby homolog 1", "gene_name": "CBY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFFGNTFSPKKTPPRKSASLSNLHSLDRSTREVELGLEYGSPTMNLAGQSLKFENGQWIAETGVSGGVDRREVQRLRRRNQQLEEENNLLRLKVDILLDMLSESTAESHLMEKELDELRISRKRK", "length": 126 }, "evidence": [ { "id": "E1BT07", "url": "https://omabrowser.org/oma/group/E1BT07/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BT07", "url": "https://www.uniprot.org/uniprotkb/E1BT07" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "E1BT07", "url": "https://www.uniprot.org/uniprotkb/E1BT07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BT07-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 126, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BT07-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BT07" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSI1-1", "uniprot_ac": "E1BSI1", "uniprot_id": "E1BSI1_CHICK", "mass": { "chemical_mass": 33045.0, "monoisotopic_mass": 33045.0 }, "refseq": { "ac": "XP_416728", "name": "vacuolar protein sorting-associated protein 26C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416728" }, "gene_names": [ { "name": "DSCR3", "type": "recommended", "evidence": [ { "id": "E1BSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSI1" } ] }, { "name": "DSCR3", "type": "synonym", "evidence": [ { "id": "XP_416728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416728" } ] } ], "protein_names": [ { "name": "Vacuolar protein sorting-associated protein 26C", "type": "recommended", "evidence": [ { "id": "E1BSI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSI1/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting-associated protein 26C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416728" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416728" } ] }, { "annotation": "Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. Component of the retriever complex, which is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retriever and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2U421", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U421#function" }, { "database": "UniProtKB", "id": "ARBA00093280", "url": "https://www.uniprot.org/uniprotkb/ARBA00093280#function" }, { "database": "UniProtKB", "id": "A0A8V0YCD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD5#function" }, { "database": "UniProtKB", "id": "A0A8V0YKR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR5#function" }, { "database": "UniProtKB", "id": "E1BSI1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSI1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DSCR3", "url": "https://www.uniprot.org/uniprotkb/E1BSI1", "locus": {} } ], "crossref": [ { "id": "E1BSI1", "url": "https://alphafold.ebi.ac.uk/entry/E1BSI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016052", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016052", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418519", "url": "https://www.ncbi.nlm.nih.gov/gene/418519", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CVTMPIT", "url": "https://omabrowser.org/oma/group/CVTMPIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U421", "url": "https://www.orthodb.org/?gene=A0A3Q2U421", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCD5", "url": "https://www.orthodb.org/?gene=A0A8V0YCD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKR5", "url": "https://www.orthodb.org/?gene=A0A8V0YKR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSI1", "url": "https://www.orthodb.org/?gene=E1BSI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U421", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U421", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U421-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U421-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSI1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSI1-1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTALDIKIKRANKVYRCGEILSGVVVITSKDTVQHQGISLTMEGSVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKLPSGKTEIPFEFPLHVKGNKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSLSQKGKLTPSPVDFTITPETLQNVKERASLPKFLIRGHLSSTNCVITQPLTGELVVESAEAAVKSIELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLPIPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHDDHLITENFPLKLCRM", "length": 297, "header": "tr|E1BSI1-1|E1BSI1_CHICK Isoform 1 of Vacuolar protein sorting-associated protein 26C OS=Gallus gallus OX=9031 GN=DSCR3 PE=1 SV=1 CANONICAL=E1BSI1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U421-1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1/entry#A0A3Q2U421-1", "sequence": { "sequence": "MGTALDIKIKRANKVYRCGEILSGVVVITSKDTVQHQGISLTMEGSVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKLPSGKTEIPFEFPLHVKGNKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSLSQKGKLTPSPVDFTITPETLQNVKERASLPKFLIRGHLSSTNCVITQPLTGELVVESAEAAVKSIELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLPIPIYMVFPRLFTCPTLETTNFKVGNGMNHYARKNKDIYFPVEVP", "length": 291, "header": "tr|A0A3Q2U421-1|A0A3Q2U421_CHICK Computationally mapped isoform of Vacuolar protein sorting-associated protein 26C OS=Gallus gallus OX=9031 GN=DSCR3 PE=1 SV=1 CANONICAL=E1BSI1-1" }, "locus": { "chromosome": "1", "start_pos": 107172744, "end_pos": 107158244, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031585.1", "url": "https://www.ensembl.org/id/ENSGALT00010031585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018455.1", "url": "https://www.ensembl.org/id/ENSGALP00010018455.1" } ] } }, { "isoform_ac": "A0A8V0YCD5-1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1/entry#A0A8V0YCD5-1", "sequence": { "sequence": "MGTALDIKIKRANKVYRCGEILSGVVVITSKDTVQHQGISLTMEGSVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKLPSGKTEIPFEFPLHVKGNKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSLRASLPKFLIRGHLSSTNCVITQPLTGELVVESAEAAVKSIELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLPIPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHDDHLITENFPLKLCRM", "length": 272, "header": "tr|A0A8V0YCD5-1|E1BSI1_CHICK Computationally mapped isoform of Vacuolar protein sorting-associated protein 26C OS=Gallus gallus OX=9031 GN=DSCR3 PE=1 SV=1 CANONICAL=E1BSI1-1" }, "locus": { "chromosome": "1", "start_pos": 107172744, "end_pos": 107157052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031592.1", "url": "https://www.ensembl.org/id/ENSGALT00010031592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018460.1", "url": "https://www.ensembl.org/id/ENSGALP00010018460.1" } ] } }, { "isoform_ac": "A0A8V0YKR5-1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1/entry#A0A8V0YKR5-1", "sequence": { "sequence": "MGTALDIKIKRANKVYRCGEILSGVVVITSKDTVQHQGISLTMEGSVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKLPSGKTEIPFEFPLHVKGNKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSLKGKLTPSPVDFTITPETLQNVKERASLPKFLIRGHLSSTNCVITQPLTGELVVESAEAAVKSIELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLPIPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHDDHLITENFPLKLCRM", "length": 295, "header": "tr|A0A8V0YKR5-1|E1BSI1_CHICK Computationally mapped isoform of Vacuolar protein sorting-associated protein 26C OS=Gallus gallus OX=9031 GN=DSCR3 PE=1 SV=1 CANONICAL=E1BSI1-1" }, "locus": { "chromosome": "1", "start_pos": 107172744, "end_pos": 107157052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031590.1", "url": "https://www.ensembl.org/id/ENSGALT00010031590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018458.1", "url": "https://www.ensembl.org/id/ENSGALP00010018458.1" } ] } }, { "isoform_ac": "E1BSI1-1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1/entry#E1BSI1-1", "sequence": { "sequence": "MGTALDIKIKRANKVYRCGEILSGVVVITSKDTVQHQGISLTMEGSVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKLPSGKTEIPFEFPLHVKGNKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSLSQKGKLTPSPVDFTITPETLQNVKERASLPKFLIRGHLSSTNCVITQPLTGELVVESAEAAVKSIELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLPIPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHDDHLITENFPLKLCRM", "length": 297, "header": "tr|E1BSI1-1|E1BSI1_CHICK Isoform 1 of Vacuolar protein sorting-associated protein 26C OS=Gallus gallus OX=9031 GN=DSCR3 PE=1 SV=1 CANONICAL=E1BSI1-1" }, "locus": { "chromosome": "1", "start_pos": 107172744, "end_pos": 107157052, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031595.1", "url": "https://www.ensembl.org/id/ENSGALT00010031595.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018463.1", "url": "https://www.ensembl.org/id/ENSGALP00010018463.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZPI7-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "VPS26C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGTTLDIKIKRANKVYHAGEMLSGVVVISGKDSVQHQGVSLTVEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTVEMAKPGKFPSGKTEIPFEFPLHVKGTKVLYETYHGVFVNIQYTLRCDMKRSLLAKDLTKTCEFIVHSAPQKGKLTPSPVDFTITPDTLQNVKERALLPKFLIRGHLNSTNCVITQPLTGELVVESSEAAIKSIELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRSLSVPIYMVFPRLFTCPTLETTNFKVEFEVNVVVLLHPDHLITENFPLKLCRM", "length": 297 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M4M6-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "Vps26c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGTSLDIKIKRANKVYHAGEMLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQILSSTIDVLKPGKLPSGKTEIPFEFPLHVKGSKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSAPQKGKLTPSPVDFTITPETLQNVKERASLPKFLIRGHLNSTNCAITQPLTGELVVEHSDAAIRSIELQLVRVETCGCAEGYARDATEIQNIQIADGDICRSLSVPLYMVFPRLFTCPTLETTNFKVEFEVNVVVLLHADHLITENFPLKLCRT", "length": 297 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E9PU42-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "Vps26c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTTLDIKIKRANKVYHAGEMLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTIDVLKPGKIPSGKTEVPFEFPLLVKGSKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSAPQKGKLTPSPVDFTITPETLQNVKERASLPKFLIRGHLNSTNCAITQPLTGELVVEHSDAAIRSIELQLVRVETCGCAEGYARDATEIQNIQIADGDICRNLSVPLYMVFPRLFTCPTLETTNFKVEFEVNVVVLLHADHLITENFPLKLCRT", "length": 297 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4HYH6-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "VPS26C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATATTVNVKLSRSNRIYRSSEPVEGKIVIKSATSISHQAIRLSVNGSVNLQVRGGSAGVIESFYGVIKPIQIVKKTIEVKSSGKIPPGTTEIPFSLNLREPGEGIVEKFYETFHGTNINIQYLLTADIPRGYLHKPLSATMEFIIESGRVDLPERPIPPEIVIFYITQDTQRHPLLPDIKTGGFRVTGKLATQCSLQDPLSGELTVEASSVPITSIDIHLLRVESIIVGERIVTETSLIQSTQIADGDVCRNMTLPIYVLLPRLLMCPSVFAGPFSVEFKVCITISFKSKLAKAQPKSDPTAPRLWMALERLPLELVRTKRDQFSC", "length": 327 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O14972-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "VPS26C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTALDIKIKRANKVYHAGEVLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTIEMVKPGKFPSGKTEIPFEFPLHLKGNKVLYETYHGVFVNIQYTLRCDMKRSLLAKDLTKTCEFIVHSAPQKGKFTPSPVDFTITPETLQNVKERALLPKFLLRGHLNSTNCVITQPLTGELVVESSEAAIRSVELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLSVPIYMVFPRLFTCPTLETTNFKVEFEVNIVVLLHPDHLITENFPLKLCRI", "length": 297 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35075-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "Vps26c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTTLDIKIKRANKVYHAGEMLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQIINSTIDVLKPGKIPSGKTEVPFEFPLLVKGSKVLYETYHGVFVNIQYTLRCDMRRSLLAKDLTKTCEFIVHSAPQKGKLTPSPVDFTITPETLQNVKERASLPKFFIRGHLNSTNCAITQPLTGELVVEHSDAAIRSIELQLVRVETCGCAEGYARDATEIQNIQIADGDICRNLSVPLYMVFPRLFTCPTLETTNFKVEFEVNVVVLLHADHLITENFPLKLCRT", "length": 297 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54DI8-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "vps26c", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNVLDLKLKKIDKIYRPGSKVSGNVVINSKDDMSHSGVTIVVEGTVQLQLSSKSVGLFEAFYNSLKPITLMHYTISVTNGGGKFQAGITELPFEFTLEPLPNQQLYDTYHGVFVNIQYSIKCDVKRGILSKDLSKTIEFIVEVPSQNKEVLMKSTPESLITFNITPDSLVNFKKISKADVPTFKISGGLVSAICNINEAFQGHMIIESADTVIKSVELQLVRVETCGCADGYAREVTEIQNIQIADGDIWRNFKIPLYMVFPRLFTCISTAGKTFKIEFEVNLVIMLEDGHLITENFPIKLIR", "length": 304 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VPC3-1", "protein_name": "Vacuolar protein sorting-associated protein 26C", "gene_name": "DSCR3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSLLFDIKLKRENKVYHENDMLLGCVQFQCAQETKHEGIILYLEGIVNLQLSAKTVGLFDAFYNSVKPINLLQNSLELSAPGKLSAGRSEFHFELPLVCKKEPRILYETYHGVFINVNYQLTCTVKRNFLGKATTKIQQFCVQYKPVPLSEDSKKVVPFSLSPDSLQKNASAKERLSMPRFLITGRLDRSEFCVTTPITGSITVQHTEAAIKSIEMQLVRVETCGCDEGYSKDATEIQTIQIADGNVLPKLELPIHMVLPRLFTCPTLLTKNFKIEFELNLIVVFKEDYTVSENFKIVLKRSTGPLPSKVTTAGR", "length": 316 }, "evidence": [ { "id": "E1BSI1", "url": "https://omabrowser.org/oma/group/E1BSI1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "E1BSI1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "E1BSI1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "E1BSI1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "E1BSI1", "url": "https://www.uniprot.org/uniprotkb/E1BSI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSI1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 297, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSI1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSI1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTE0-1", "uniprot_ac": "E1BTE0", "uniprot_id": "E1BTE0_CHICK", "mass": { "chemical_mass": 17233.0, "monoisotopic_mass": 17233.0 }, "refseq": { "ac": "NP_001264936", "name": "single-stranded DNA-binding protein, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264936" }, "gene_names": [ { "name": "SSBP1", "type": "recommended", "evidence": [ { "id": "E1BTE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ] }, { "name": "SSBP1", "type": "synonym", "evidence": [ { "id": "NP_001264936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264936" } ] } ], "protein_names": [ { "name": "Single stranded DNA binding protein 1", "type": "synonym", "evidence": [ { "id": "E1BTE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE0/entry#names_and_taxonomy" } ] }, { "name": "single-stranded DNA binding protein 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001264936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264936" } ] }, { "name": "single-stranded DNA-binding protein, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001264936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264936" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01110297.1, BX263606.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Sep 23, 2021 this sequence version replaced NP_001264936.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264936", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264936" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSBP1", "url": "https://www.uniprot.org/uniprotkb/E1BTE0", "locus": { "chromosome": "1", "start_pos": 57389713, "end_pos": 57384042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013625", "url": "https://www.ensembl.org/id/ENSGALG00010013625" } ] } } ], "crossref": [ { "id": "E1BTE0", "url": "https://alphafold.ebi.ac.uk/entry/E1BTE0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012876", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012876", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04496", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04496", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418122", "url": "https://www.ncbi.nlm.nih.gov/gene/418122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418122", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418122", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IKSRQWQ", "url": "https://omabrowser.org/oma/group/IKSRQWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YLB8", "url": "https://www.orthodb.org/?gene=A0A8V0YLB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTE0", "url": "https://www.orthodb.org/?gene=E1BTE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10302:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10302:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00436", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9913635", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913635", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264936", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264936", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YLB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YLB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTE0-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRRPAWQVFCQLVRYESGDTVGSLVLERSMNRVQLLGRVGQDPIMRQVDGKNPVTIFSLATNEMWRTGETEVAQTGDISQKTTWHRISVFRPGLRDVTYQYVKKGSRLYVEGKLDYGEYTDKNNVRRQATTIIADNVIFLSDNIKEKV", "length": 149, "header": "tr|E1BTE0-1|E1BTE0_CHICK Isoform 1 of Single stranded DNA binding protein 1 OS=Gallus gallus OX=9031 GN=SSBP1 PE=1 SV=3 CANONICAL=E1BTE0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YLB8-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE0/entry#A0A8V0YLB8-1", "sequence": { "sequence": "MWRRPAWQVFCQLVRYESGDTVGSLVLERSMNRVQLLGRVGQDPIMRQVDGKNPVTIFSLATNEMWRTGETEVAQTGDISQKTTWHRISVFRPGLRDVTYQYVKKGSRLYVEGKLDYGEYTDKNNVRRQATTIIAGEEQYTVPLCLFKWKGGGEPLKYSLVCLQNPWLRILRRLFAVSGLYH", "length": 182, "header": "tr|A0A8V0YLB8-1|E1BTE0_CHICK Computationally mapped isoform of Single stranded DNA binding protein 1 OS=Gallus gallus OX=9031 GN=SSBP1 PE=1 SV=1 CANONICAL=E1BTE0-1" }, "locus": { "chromosome": "1", "start_pos": 57388493, "end_pos": 57384245, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032731.1", "url": "https://www.ensembl.org/id/ENSGALT00010032731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019393.1", "url": "https://www.ensembl.org/id/ENSGALP00010019393.1" } ] } }, { "isoform_ac": "E1BTE0-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE0/entry#E1BTE0-1", "sequence": { "sequence": "MWRRPAWQVFCQLVRYESGDTVGSLVLERSMNRVQLLGRVGQDPIMRQVDGKNPVTIFSLATNEMWRTGETEVAQTGDISQKTTWHRISVFRPGLRDVTYQYVKKGSRLYVEGKLDYGEYTDKNNVRRQATTIIADNVIFLSDNIKEKV", "length": 149, "header": "tr|E1BTE0-1|E1BTE0_CHICK Isoform 1 of Single stranded DNA binding protein 1 OS=Gallus gallus OX=9031 GN=SSBP1 PE=1 SV=3 CANONICAL=E1BTE0-1" }, "locus": { "chromosome": "1", "start_pos": 57389575, "end_pos": 57384245, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032736.1", "url": "https://www.ensembl.org/id/ENSGALT00010032736.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019396.1", "url": "https://www.ensembl.org/id/ENSGALP00010019396.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418122", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418122", "resource": "KEGG Pathway" }, { "id": "R-GGA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" }, { "id": "R-GGA-9913635", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913635", "resource": "Reactome", "description": "Strand-asynchronous mitochondrial DNA replication" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A6V6-1", "protein_name": "Single-stranded DNA-binding protein", "gene_name": "SSBP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFRRPVFQVLHQFVRHESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGENEAYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSRVYVEGKVDYGEYTDKNNVRRQATTIIADNIIFLSDQVKEKA", "length": 148 }, "evidence": [ { "id": "E1BTE0", "url": "https://omabrowser.org/oma/group/E1BTE0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HGL0-1", "protein_name": "Single-stranded DNA-binding protein", "gene_name": "Ssbp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFRRPVLQVFHQFVRHESEVASSLVLERSMNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDSEVYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIADNIIFLSDQIKEKS", "length": 148 }, "evidence": [ { "id": "E1BTE0", "url": "https://omabrowser.org/oma/group/E1BTE0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P28042-1", "protein_name": "Single-stranded DNA-binding protein, mitochondrial", "gene_name": "Ssbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRRPVLQVFRQFVRQESEVASSLVLERSLNRVQLLGRVGQDPVMRQVEGKNPVTIFSLATNEMWRSGDNEAYQMGDVSQKTTWHRISVFRPGLRDVAYQYVKKGARIFVEGKVDYGEYMDKNNVRRQATTIIADNIIFLSDQAREKPLNG", "length": 151 }, "evidence": [ { "id": "E1BTE0", "url": "https://omabrowser.org/oma/group/E1BTE0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P54622-1", "protein_name": "Single-stranded DNA-binding protein, mitochondrial", "gene_name": "mtSSB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQHTRRMLNPLLTGLRNLPARGATTTTAAAPAKVEKTVNTVTILGRVGADPQLRGSQEHPVVTFSVATHTNYKYENGDWAQRTDWHRVVVFKPNLRDTVLEYLKKGQRTMVQGKITYGEITDQQGNQKTSTSIIADDVLFFRDANN", "length": 146 }, "evidence": [ { "id": "E1BTE0", "url": "https://omabrowser.org/oma/group/E1BTE0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of mitochondrial DNA replication", "id": "GO:0090297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090297", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" }, { "name": "protein homotetramerization", "id": "GO:0051289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051289", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" }, { "name": "mitochondrial DNA replication", "id": "GO:0006264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006264", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "E1BTE0", "url": "https://www.uniprot.org/uniprotkb/E1BTE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BR96-1", "uniprot_ac": "E1BR96", "uniprot_id": "E1BR96_CHICK", "mass": { "chemical_mass": 45071.0, "monoisotopic_mass": 45071.0 }, "refseq": { "ac": "XP_015153405", "name": "NIPA-like protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153405" }, "gene_names": [ { "name": "NIPAL3", "type": "recommended", "evidence": [ { "id": "E1BR96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BR96" } ] }, { "name": "NIPAL3", "type": "synonym", "evidence": [ { "id": "XP_015153405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153405" } ] } ], "protein_names": [ { "name": "NIPA like domain containing 3", "type": "synonym", "evidence": [ { "id": "E1BR96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BR96/entry#names_and_taxonomy" } ] }, { "name": "NIPA-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015153405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153405" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015153405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153405" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BR96", "url": "https://www.uniprot.org/uniprotkb/E1BR96" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIPAL3", "url": "https://www.uniprot.org/uniprotkb/E1BR96", "locus": { "chromosome": "23", "start_pos": 6135424, "end_pos": 6123622, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015855", "url": "https://www.ensembl.org/id/ENSGALG00010015855" } ] } } ], "crossref": [ { "id": "E1BR96", "url": "https://alphafold.ebi.ac.uk/entry/E1BR96", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004268", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004268", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419697", "url": "https://www.ncbi.nlm.nih.gov/gene/419697", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008521", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008521", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PYVTMDV", "url": "https://omabrowser.org/oma/group/PYVTMDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YM47", "url": "https://www.orthodb.org/?gene=A0A8V0YM47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTI6", "url": "https://www.orthodb.org/?gene=A0A8V0YTI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z092", "url": "https://www.orthodb.org/?gene=A0A8V0Z092", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BR96", "url": "https://www.orthodb.org/?gene=E1BR96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015153405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015153405", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YM47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YM47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z092", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z092", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z092-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z092-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BR96", "url": "https://www.uniprot.org/uniprotkb/E1BR96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BR96-1", "url": "https://www.uniprot.org/uniprotkb/E1BR96-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGNSPNMQLQQIPLATAAVSVQPHTDSFSYKENLIGALLAIFGHLVISIALNLQKYSHIRLAGSKDSRAYFKTKTWWCGLFLLVLGELGVFSSYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKEFLRRYVLSFVGCGLAIVGTYLLITFGPNSHEKMTGENITRHLVSWPFLLYMLVEIIIFCLLLYFYKEKNANYIVIILLLVALLGSMTVVTVKAVAGMIVVSIRGNLQLNYPIFYIMLVCMIATAVFQATFLAQASQLYDSSQIASIGYILSTTVAITAGATFYLDFTGEDVLHICMFALGCLIAFLGVFLITRNRKKSVPFEPYISMDAMPGMQNMHDKGIAVQPDLKASFSYGALENNDNMPEIYTPATLPIVQEQHGSRGVSAPPYRVLEHSKKE", "length": 408, "header": "tr|E1BR96-1|E1BR96_CHICK Isoform 1 of NIPA like domain containing 3 OS=Gallus gallus OX=9031 GN=NIPAL3 PE=3 SV=1 CANONICAL=E1BR96-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YM47-1", "url": "https://www.uniprot.org/uniprotkb/E1BR96/entry#A0A8V0YM47-1", "sequence": { "sequence": "MEGGNSPNMQLQQIPLATAAVSVQPHTDSFSYKENLIGALLAIFGHLVISIALNLQKYSHIRLAGSKDSRAYFKTKTWWCGLFLLVLGELGVFSSYAFAPLSLIVPLSAVSVIGRYVLSFVGCGLAIVGTYLLITFGPNSHEKMTGENITRHLVSWPFLLYMLVEIIIFCLLLYFYKEKNANYIVIILLLVALLGSMTVVTVKAVAGMIVVSIRGNLQLNYPIFYIMLVCMIATAVFQATFLAQASQLYDSSQIASIGYILSTTVAITAGATFYLDFTGEDVLHICMFALGCLIAFLGVFLITRNRKKSVPFEPYISMDAMPGMQNMHDKGIAVQPDLKASFSYGALENNDNMPEIYTPATLPIVQEQHGSRGVSAPPYRVLEHSKKE", "length": 388, "header": "tr|A0A8V0YM47-1|E1BR96_CHICK Computationally mapped isoform of NIPA like domain containing 3 OS=Gallus gallus OX=9031 GN=NIPAL3 PE=3 SV=1 CANONICAL=E1BR96-1" }, "locus": { "chromosome": "23", "start_pos": 6132269, "end_pos": 6124933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038192.1", "url": "https://www.ensembl.org/id/ENSGALT00010038192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022042.1", "url": "https://www.ensembl.org/id/ENSGALP00010022042.1" } ] } }, { "isoform_ac": "A0A8V0YTI6-1", "url": "https://www.uniprot.org/uniprotkb/E1BR96/entry#A0A8V0YTI6-1", "sequence": { "sequence": "MEGGNSPNMQLQQIPLATAAVSVQPHTDSFSYKNLIGALLAIFGHLVISIALNLQKYSHIRLAGSKDSRAYFKTKTWWCGLFLLVLGELGVFSSYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKEFLRRYVLSFVGCGLAIVGTYLLITFGPNSHEKMTGENITRHLVSWPFLLYMLVEIIIFCLLLYFYKEKNANYIVIILLLVALLGSMTVVTVKAVAGMIVVSIRGNLQLNYPIFYIMLVCMIATAVFQATFLAQASQLYDSSQIASIGYILSTTVAITAGATFYLDFTGEDVLHICMFALGCLIAFLGVFLITRNRKKSVPFEPYISMDAMPGMQNMHDKGIAVQPDLKASFSYGALENNDNMPEIYTPATLPIVQEQHGSRGVSAPPYRVLEHSKKE", "length": 407, "header": "tr|A0A8V0YTI6-1|E1BR96_CHICK Computationally mapped isoform of NIPA like domain containing 3 OS=Gallus gallus OX=9031 GN=NIPAL3 PE=3 SV=1 CANONICAL=E1BR96-1" }, "locus": { "chromosome": "23", "start_pos": 6132269, "end_pos": 6124933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038194.1", "url": "https://www.ensembl.org/id/ENSGALT00010038194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022044.1", "url": "https://www.ensembl.org/id/ENSGALP00010022044.1" } ] } }, { "isoform_ac": "A0A8V0Z092-1", "url": "https://www.uniprot.org/uniprotkb/E1BR96/entry#A0A8V0Z092-1", "sequence": { "sequence": "MEGGNSPNMQLQQIPLATAAVSVQPHTDSFSYKENLIGALLAIFGHLVISIALNLQKYSHIRLAGSKDSRAYFKTKTWWCGLFLLVLGELGVFSSYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKEFLRRYVLSFVGCGLAIVGTYLLITFGPNSHEKMTGENITRHLVSWPFLLYMLVEIIIFCLLLYFYKEKNANYIVIILLLVALLGSMTVVTVKAVAGMIVVSIRGNLQLNYPIFYIMLVCMIATAVFQATFLAQASQLYDSSQIASIGYILSTTVAITAGATFYLDFTGEDVLHICMFALGCLIAFLGVFLITRNRKKSVPFEPYISMDAMPGNSFEHLLGIGLHHVCKTCMTKGLQFSLTSKLPFPMVP", "length": 380, "header": "tr|A0A8V0Z092-1|E1BR96_CHICK Computationally mapped isoform of NIPA like domain containing 3 OS=Gallus gallus OX=9031 GN=NIPAL3 PE=3 SV=1 CANONICAL=E1BR96-1" }, "locus": { "chromosome": "23", "start_pos": 6132144, "end_pos": 6124933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038193.1", "url": "https://www.ensembl.org/id/ENSGALT00010038193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022043.1", "url": "https://www.ensembl.org/id/ENSGALP00010022043.1" } ] } }, { "isoform_ac": "E1BR96-1", "url": "https://www.uniprot.org/uniprotkb/E1BR96/entry#E1BR96-1", "sequence": { "sequence": "MEGGNSPNMQLQQIPLATAAVSVQPHTDSFSYKENLIGALLAIFGHLVISIALNLQKYSHIRLAGSKDSRAYFKTKTWWCGLFLLVLGELGVFSSYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKEFLRRYVLSFVGCGLAIVGTYLLITFGPNSHEKMTGENITRHLVSWPFLLYMLVEIIIFCLLLYFYKEKNANYIVIILLLVALLGSMTVVTVKAVAGMIVVSIRGNLQLNYPIFYIMLVCMIATAVFQATFLAQASQLYDSSQIASIGYILSTTVAITAGATFYLDFTGEDVLHICMFALGCLIAFLGVFLITRNRKKSVPFEPYISMDAMPGMQNMHDKGIAVQPDLKASFSYGALENNDNMPEIYTPATLPIVQEQHGSRGVSAPPYRVLEHSKKE", "length": 408, "header": "tr|E1BR96-1|E1BR96_CHICK Isoform 1 of NIPA like domain containing 3 OS=Gallus gallus OX=9031 GN=NIPAL3 PE=3 SV=1 CANONICAL=E1BR96-1" }, "locus": { "chromosome": "23", "start_pos": 6132269, "end_pos": 6124933, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038191.1", "url": "https://www.ensembl.org/id/ENSGALT00010038191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022041.1", "url": "https://www.ensembl.org/id/ENSGALP00010022041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5YC77-1", "protein_name": "NIPA-like domain containing 3", "gene_name": "Nipal3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGAHSAGLQLQPLSPTSGATSPSLSSGEGSFSYKENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLLLLLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFVRRYVLSFVGCGLAIVGTYLLVTFAPNSHEKMTGENIARHLVSWPFLLYMLVAIVLFCLLLYFYKEKNANSIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAIYQATFLSQASQIYDSSLIASVGYILSTTVAITAGSIFYLDFLGEEALHICMFALGCLIAFLGVFLITRNRKKAIPFEPYISMDAMPGMQDMHAKGMTVQPDLKASFSYGALENNDSISEIYTPATLPVMQEEHSSRSTPGVPYRVLEHTKKE", "length": 410 }, "evidence": [ { "id": "E1BR96", "url": "https://omabrowser.org/oma/group/E1BR96/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BLE7-1", "protein_name": "NIPA like domain containing 3", "gene_name": "NIPAL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDGAHGAALQLQQLLPTSSANPVREASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYILSFVGCGLAIVGTYLLVTFGPNSHEKMTGDNIIRHLVSWPFLLYMLVEIILFCLLLYFYKERNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAIYQAAFLGQASQMYDSSLIASVGYILSTTVAITAGAVFYLDFLGQDVLHVCMFALGCLIAFLGVFLITRNRKKAIPFEPYISMDAMPGMQNMHDKGMTVQPDLKASFSYGALENNDNISEIYAPATLPVMQEEHGSRNASGVPYRVLEHTKKE", "length": 406 }, "evidence": [ { "id": "E1BR96", "url": "https://omabrowser.org/oma/group/E1BR96/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P499-1", "protein_name": "NIPA-like protein 3", "gene_name": "NIPAL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGSHSAALKLQQLPPTSSSSAVSEASFSYKENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLFLMLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFLRRYVLSFVGCGLAVVGTYLLVTFAPNSHEKMTGENVTRHLVSWPFLLYMLVEIILFCLLLYFYKEKNANNIVVILLLVALLGSMTVVTVKAVAGMLVLSIQGNLQLDYPIFYVMFVCMVATAVYQAAFLSQASQMYDSSLIASVGYILSTTIAITAGAIFYLDFIGEDVLHICMFALGCLIAFLGVFLITRNRKKPIPFEPYISMDAMPGMQNMHDKGMTVQPELKASFSYGALENNDNISEIYAPATLPVMQEEHGSRSASGVPYRVLEHTKKE", "length": 406 }, "evidence": [ { "id": "E1BR96", "url": "https://omabrowser.org/oma/group/E1BR96/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGN5-1", "protein_name": "NIPA-like protein 3", "gene_name": "Nipal3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGAHSAGLQLQPLPPTSGATSTSLSSSEGSFSYKENLIGALLAIFGHLVVSIALNLQKYCHIRLAGSKDPRAYFKTKTWWLGLLLLLLGELGVFASYAFAPLSLIVPLSAVSVIASAIIGIIFIKEKWKPKDFVRRYVLSFVGCGLAIVGTYLLVTFAPNSHEKMTGENIARHLVSWPFLLYMLVAIVLFCLLLYFYKERNANSIVVILLLVALLGSMTVVTVKAVSGMLVLSIQGNLQLDYPIFYVMFVCMVATAIYQATFLSEASQIYDSSLIASVGYILSTTAAITAGAIFYLDFLGEEALHICMFALGCLIAFLGVFLITRNRKKAIPFEPYISMDAMPGMQDMHAKGTTVQPDLKASFSYGALESNDSISELYTPATLPVMQEEHSSRSTPGVPYRVLEHTKKE", "length": 410 }, "evidence": [ { "id": "E1BR96", "url": "https://omabrowser.org/oma/group/E1BR96/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BR96", "url": "https://www.uniprot.org/uniprotkb/E1BR96" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "magnesium ion transmembrane transporter activity", "id": "GO:0015095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015095", "evidence": [ { "database": "UniProtKB", "id": "E1BR96", "url": "https://www.uniprot.org/uniprotkb/E1BR96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "magnesium ion transport", "id": "GO:0015693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015693", "evidence": [ { "database": "UniProtKB", "id": "E1BR96", "url": "https://www.uniprot.org/uniprotkb/E1BR96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BR96-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 408, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BR96-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BR96" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BT86-1", "uniprot_ac": "E1BT86", "uniprot_id": "E1BT86_CHICK", "mass": { "chemical_mass": 18939.0, "monoisotopic_mass": 18939.0 }, "refseq": { "ac": "XP_419388", "name": "protein cornichon homolog 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419388" }, "gene_names": [ { "name": "CNIH3", "type": "recommended", "evidence": [ { "id": "E1BT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ] }, { "name": "CNIH3", "type": "synonym", "evidence": [ { "id": "XP_419388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419388" } ] } ], "protein_names": [ { "name": "Cornichon family AMPA receptor auxiliary protein 3", "type": "synonym", "evidence": [ { "id": "E1BT86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT86/entry#names_and_taxonomy" } ] }, { "name": "protein cornichon homolog 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419388" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_419388.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419388", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419388" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CNIH3", "url": "https://www.uniprot.org/uniprotkb/E1BT86", "locus": { "chromosome": "3", "start_pos": 17148027, "end_pos": 17220049, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016477", "url": "https://www.ensembl.org/id/ENSGALG00010016477" } ] } } ], "crossref": [ { "id": "E1BT86", "url": "https://alphafold.ebi.ac.uk/entry/E1BT86", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009308", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009308", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421323", "url": "https://www.ncbi.nlm.nih.gov/gene/421323", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VFYHFWR", "url": "https://omabrowser.org/oma/group/VFYHFWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPM8", "url": "https://www.orthodb.org/?gene=A0A8V0YPM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BT86", "url": "https://www.orthodb.org/?gene=E1BT86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5694530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419388", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419388", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT86-1", "url": "https://www.uniprot.org/uniprotkb/E1BT86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPAHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFRCPADSSELAYDPPAVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS", "length": 160, "header": "tr|E1BT86-1|E1BT86_CHICK Isoform 1 of Cornichon family AMPA receptor auxiliary protein 3 OS=Gallus gallus OX=9031 GN=CNIH3 PE=3 SV=1 CANONICAL=E1BT86-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YPM8-1", "url": "https://www.uniprot.org/uniprotkb/E1BT86/entry#A0A8V0YPM8-1", "sequence": { "sequence": "GGRARRGLAVLGAQTAQLRALRRLLLLLLAPSCPVGLHGAAAAARAAAATSERGGGGDEPGGERGGLRRGEACSARGSPGLSCSLRRRRRGGPGFLPRGRGGSAGVRVGGGGSGGQSFLAESGRGLSGNSYHTVHYSAELPHKIIAFDELRTDFKSPIDQCNPAHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFRCPADSSELAYDPPAVMNADTLSYCQKEAWCKLAFYLLSFFYYLYW", "length": 268, "header": "tr|A0A8V0YPM8-1|E1BT86_CHICK Computationally mapped isoform of Cornichon family AMPA receptor auxiliary protein 3 OS=Gallus gallus OX=9031 GN=CNIH3 PE=3 SV=1 CANONICAL=E1BT86-1" }, "locus": { "chromosome": "3", "start_pos": 17220049, "end_pos": 17150037, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039697.1", "url": "https://www.ensembl.org/id/ENSGALT00010039697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022956.1", "url": "https://www.ensembl.org/id/ENSGALP00010022956.1" } ] } }, { "isoform_ac": "E1BT86-1", "url": "https://www.uniprot.org/uniprotkb/E1BT86/entry#E1BT86-1", "sequence": { "sequence": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPAHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFRCPADSSELAYDPPAVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS", "length": 160, "header": "tr|E1BT86-1|E1BT86_CHICK Isoform 1 of Cornichon family AMPA receptor auxiliary protein 3 OS=Gallus gallus OX=9031 GN=CNIH3 PE=3 SV=1 CANONICAL=E1BT86-1" }, "locus": { "chromosome": "3", "start_pos": 17189035, "end_pos": 17149135, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039691.1", "url": "https://www.ensembl.org/id/ENSGALT00010039691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022950.1", "url": "https://www.ensembl.org/id/ENSGALP00010022950.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2ML86-1", "protein_name": "Protein cornichon homolog 3 isoform X1", "gene_name": "Cnih3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS", "length": 160 }, "evidence": [ { "id": "E1BT86", "url": "https://omabrowser.org/oma/group/E1BT86/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9S3Y6-1", "protein_name": "Cornichon family AMPA receptor auxiliary protein 3", "gene_name": "CNIH3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRATKHARSSFPNQGLNPSPLQQKHGVLTLDNQGSPGPELSLPEKFKICVCVLSPGIERKIIAFDELRTDFKSPIDQCNPLHALVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS", "length": 177 }, "evidence": [ { "id": "E1BT86", "url": "https://omabrowser.org/oma/group/E1BT86/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AB32T7A5-1", "protein_name": "Protein cornichon homolog 3 isoform X1", "gene_name": "cnih3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFTFAAFCYMLSLVLCASLIFFAIWHITAFDELQADFKVPIDQGNPLHARERLRNIERICCLLRKQNWHSAVAKNCPVLPQLKLVLPEYSIHVLFCIMFLCAQEWLTVGLNIPLLFYNTWSRYFHSPTDTKELLYDPASVMNGDTLKFCQKEAWCKMSFFVLSFFYYLYCMIYTLVTS", "length": 178 }, "evidence": [ { "id": "E1BT86", "url": "https://omabrowser.org/oma/group/E1BT86/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D0Q0Y7-1", "protein_name": "Protein cornichon homolog 3", "gene_name": "Cnih3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRKLVLPEYSIHSLFCVMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS", "length": 160 }, "evidence": [ { "id": "E1BT86", "url": "https://omabrowser.org/oma/group/E1BT86/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZWS4-1", "protein_name": "Protein cornichon homolog 3", "gene_name": "Cnih3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS", "length": 160 }, "evidence": [ { "id": "E1BT86", "url": "https://omabrowser.org/oma/group/E1BT86/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBE1-1", "protein_name": "Protein cornichon homolog 3", "gene_name": "CNIH3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFTFAAFCYMLSLVLCAALIFFAIWHIIAFDELRTDFKSPIDQCNPVHARERLRNIERICFLLRKLVLPEYSIHSLFCIMFLCAQEWLTLGLNVPLLFYHFWRYFHCPADSSELAYDPPVVMNADTLSYCQKEAWCKLAFYLLSFFYYLYCMIYTLVSS", "length": 160 }, "evidence": [ { "id": "E1BT86", "url": "https://omabrowser.org/oma/group/E1BT86/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "E1BT86", "url": "https://www.uniprot.org/uniprotkb/E1BT86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTJ9-1", "uniprot_ac": "E1BTJ9", "uniprot_id": "E1BTJ9_CHICK", "mass": { "chemical_mass": 107494.0, "monoisotopic_mass": 107494.0 }, "refseq": { "ac": "XP_040506969", "name": "serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506969" }, "gene_names": [ { "name": "PPP4R1L", "type": "recommended", "evidence": [ { "id": "E1BTJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9" } ] }, { "name": "PPP4R1L", "type": "synonym", "evidence": [ { "id": "XP_040506969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506969" } ] } ], "protein_names": [ { "name": "Protein phosphatase 4 regulatory subunit 1 like (pseudo", "type": "synonym", "evidence": [ { "id": "E1BTJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040506969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506969" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506969" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTJ9", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP4R1L", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9", "locus": {} } ], "crossref": [ { "id": "E1BTJ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BTJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007575", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007575", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419319", "url": "https://www.ncbi.nlm.nih.gov/gene/419319", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KFFNLCS", "url": "https://omabrowser.org/oma/group/KFFNLCS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRX4", "url": "https://www.orthodb.org/?gene=A0A8V0YRX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTJ9", "url": "https://www.orthodb.org/?gene=E1BTJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10648", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10648", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10648:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10648:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506969", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YRX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTJ9", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGIPLYFVDLQDDLDDFGFEDYGPDCDSMRITAFLDIPGQDNLTPLARLEKYAFSENVFNRQIIARGLLDVFRDFSNNEEDFLTVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQESRPKFPTAFFEYLMPIVVRYLTDVNNQVRKAGQEALLILLEQDLVSQSDIENKVCPILLDLSAPDSDDEYKVEAVNIICKMASMLSRTTVEHLLLPRFCELCSDGKLFQVRKICAANFGDICNAVGQEATERLLIPKFFELCSDSVWGMRKACAECFMAVSYTTSPEVRRSKLSPLFISLISDTCRWVRQAAFQSLGPFISTFANPSSAGLYIREDGTLSIRPSVQDVNSNSCQPTNNITVIASTANAASCSLEQPMEIKSESSTEETSAEVHVPLSVENLNRNTWEASSDCYMSSGEDLSRLSQDDGVGAGVAEVAKDINFPGITSRLQCSEDVFNTFLYWRPPLPDISQDLELLQFKTEKHKESCSVPCNNCVASSEIKKVLESLQEHIDDPDVQAQVQVLSAALRAAQFDSVGDCETRKMEESSGELQNKTISDQTAVSDATCNRVEEDTLSSSVSQDGITEQPTTSILKSTDSEQPRATSVFLKKEQESPPPFEDDKSKLQDIIPQPLLDQYLSMTDPARAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLKDTYETLASDVQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLYDFLKLLHADKRREYLYQLQEFVVTDNSRNWRFRYELAEQLILILELYNPNDVYDYLRHIALTLCSDKVSEVRWISFKLVVAILQKFYANNANALGLNFINELVVRFRHCSKWVGRQAFAFICQAVVEEECMPVDQFVEHLLPSLLSLASDPVPNVRVLLAKALRQTLLEKAYFKSVGNPHLEAAEETILALQSDSDQDVSFFATIKLKQNNMDSTPTEKQT", "length": 956, "header": "tr|E1BTJ9-1|E1BTJ9_CHICK Isoform 1 of Protein phosphatase 4 regulatory subunit 1 like (pseudo OS=Gallus gallus OX=9031 GN=PPP4R1L PE=4 SV=2 CANONICAL=E1BTJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YRX4-1", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9/entry#A0A8V0YRX4-1", "sequence": { "sequence": "MAVGFEDYGPDCDSMRITAFLDIPGQDNLTPLARLEKYAFSENVFNRQIIARGLLDVFRDFSNNEEDFLTVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQESRPKFPTAFFEYLMPIVVRYLTDVNNQVRKAGQEALLILLEQDLVSQSDIENKVCPILLDLSAPDSDDEYKVEAVNIICKMASMLSRTTVEHLLLPRFCELCSDGKLFQVRKICAANFGDICNAVGQEATERLLIPKFFELCSDSVWGMRKACAECFMAVSYTTSPEVRRSKLSPLFISLISDTCRWVRQAAFQSLGPFISTFANPSSAGLYIREDGTLSIRPSVQDVNSNSCQPTNNITVIASTANAASCSLEQPMEIKSESSTEETSAEVHVPLSVENLNRNTWEASSDCYMSSGEDLSRLSQDDGVGAGVAEVAKDINFPGITSRLQCSEDVFNTFLYWRPPLPDISQDLELLQFKTEKHKESCSVPCNNCVASSEIKKVLESLQEHIDDPDVQAQVQVLSAALRAAQFDSVGDCETRKMEESSGELQNKTISDQTAVSDATCNRVEEDTLSSSVSQDGITEQPTTSILKSTDSEQPRATSVFLKKEQESPPPFEDDKSKLQDIIPQPLLDQYLSMTDPARAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLKDTYETLASDVQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLYDFLKLLHADKRREYLYQLQEFVVTDNSRNWRFRYELAEQLILILELYNPNDVYDYLRHIALTLCSDKVSEVRWISFKLVVAILQKFYANNANALGLNFINELVVRFRHCSKWVGRQAFAFICQAVVEEECMPVDQFVEHLLPSLLSLASDPVPNVRVLLAKALRQTLLEKAYFKSVGNPHLEAAEETILALQSDSDQDVSFFATIKLKQNNMDSTPTEKQT", "length": 941, "header": "tr|A0A8V0YRX4-1|E1BTJ9_CHICK Computationally mapped isoform of Protein phosphatase 4 regulatory subunit 1 like (pseudo OS=Gallus gallus OX=9031 GN=PPP4R1L PE=4 SV=1 CANONICAL=E1BTJ9-1" }, "locus": { "chromosome": "20", "start_pos": 11591222, "end_pos": 11573383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035871.1", "url": "https://www.ensembl.org/id/ENSGALT00010035871.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020809.1", "url": "https://www.ensembl.org/id/ENSGALP00010020809.1" } ] } }, { "isoform_ac": "E1BTJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9/entry#E1BTJ9-1", "sequence": { "sequence": "MAGIPLYFVDLQDDLDDFGFEDYGPDCDSMRITAFLDIPGQDNLTPLARLEKYAFSENVFNRQIIARGLLDVFRDFSNNEEDFLTVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQESRPKFPTAFFEYLMPIVVRYLTDVNNQVRKAGQEALLILLEQDLVSQSDIENKVCPILLDLSAPDSDDEYKVEAVNIICKMASMLSRTTVEHLLLPRFCELCSDGKLFQVRKICAANFGDICNAVGQEATERLLIPKFFELCSDSVWGMRKACAECFMAVSYTTSPEVRRSKLSPLFISLISDTCRWVRQAAFQSLGPFISTFANPSSAGLYIREDGTLSIRPSVQDVNSNSCQPTNNITVIASTANAASCSLEQPMEIKSESSTEETSAEVHVPLSVENLNRNTWEASSDCYMSSGEDLSRLSQDDGVGAGVAEVAKDINFPGITSRLQCSEDVFNTFLYWRPPLPDISQDLELLQFKTEKHKESCSVPCNNCVASSEIKKVLESLQEHIDDPDVQAQVQVLSAALRAAQFDSVGDCETRKMEESSGELQNKTISDQTAVSDATCNRVEEDTLSSSVSQDGITEQPTTSILKSTDSEQPRATSVFLKKEQESPPPFEDDKSKLQDIIPQPLLDQYLSMTDPARAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLKDTYETLASDVQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLYDFLKLLHADKRREYLYQLQEFVVTDNSRNWRFRYELAEQLILILELYNPNDVYDYLRHIALTLCSDKVSEVRWISFKLVVAILQKFYANNANALGLNFINELVVRFRHCSKWVGRQAFAFICQAVVEEECMPVDQFVEHLLPSLLSLASDPVPNVRVLLAKALRQTLLEKAYFKSVGNPHLEAAEETILALQSDSDQDVSFFATIKLKQNNMDSTPTEKQT", "length": 956, "header": "tr|E1BTJ9-1|E1BTJ9_CHICK Isoform 1 of Protein phosphatase 4 regulatory subunit 1 like (pseudo OS=Gallus gallus OX=9031 GN=PPP4R1L PE=4 SV=2 CANONICAL=E1BTJ9-1" }, "locus": { "chromosome": "20", "start_pos": 11591222, "end_pos": 11573383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035872.1", "url": "https://www.ensembl.org/id/ENSGALT00010035872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020810.1", "url": "https://www.ensembl.org/id/ENSGALP00010020810.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BTJ9", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "E1BTJ9", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BTJ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 956, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BTJ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BTJ9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BTJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTJ9" }, { "id": "PF15017", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Putative WW-binding", "eco_id": "ECO_0000259", "start_pos": 453, "end_pos": 492, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 356, "end_pos": 358 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 550, "end_pos": 552 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BYP8-1", "uniprot_ac": "E1BYP8", "uniprot_id": "E1BYP8_CHICK", "mass": { "chemical_mass": 76996.0, "monoisotopic_mass": 76996.0 }, "refseq": { "ac": "NP_001385177", "name": "glycerophosphocholine phosphodiesterase GPCPD1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385177" }, "gene_names": [ { "name": "GPCPD1", "type": "recommended", "evidence": [ { "id": "E1BYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ] }, { "name": "GPCPD1", "type": "synonym", "evidence": [ { "id": "NP_001385177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385177" } ] } ], "protein_names": [ { "name": "Glycerophosphocholine phosphodiesterase GPCPD1", "type": "recommended", "evidence": [ { "id": "E1BYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYP8/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.2", "type": "synonym", "evidence": [ { "id": "E1BYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYP8/entry#names_and_taxonomy" } ] }, { "name": "Glycerophosphodiester phosphodiesterase 5", "type": "synonym", "evidence": [ { "id": "E1BYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYP8/entry#names_and_taxonomy" } ] }, { "name": "glycerophosphocholine phosphodiesterase GDE1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001385177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385177" } ] }, { "name": "glycerophosphocholine phosphodiesterase GDE1-like protein", "type": "synonym", "evidence": [ { "id": "NP_001385177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385177" } ] }, { "name": "glycerophosphocholine phosphodiesterase GPCPD1", "type": "synonym", "evidence": [ { "id": "NP_001385177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385177" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267661.28888.1, SRR13267659.9589.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. On Dec 10, 2021 this sequence version replaced XP_004935341.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001385177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385177" } ] }, { "annotation": "May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z0Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Q7#function" }, { "database": "UniProtKB", "id": "ARBA00059394", "url": "https://www.uniprot.org/uniprotkb/ARBA00059394#function" }, { "database": "UniProtKB", "id": "A0A8V0Z0R2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R2#function" }, { "database": "UniProtKB", "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPCPD1", "url": "https://www.uniprot.org/uniprotkb/E1BYP8", "locus": { "chromosome": "3", "start_pos": 16449733, "end_pos": 16491801, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017352", "url": "https://www.ensembl.org/id/ENSGALG00010017352" } ] } } ], "crossref": [ { "id": "E1BYP8", "url": "https://alphafold.ebi.ac.uk/entry/E1BYP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009130", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009130", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05814", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05814", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08607", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08607", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421311", "url": "https://www.ncbi.nlm.nih.gov/gene/421311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LKVYHTA", "url": "https://omabrowser.org/oma/group/LKVYHTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0Q7", "url": "https://www.orthodb.org/?gene=A0A8V0Z0Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z0R2", "url": "https://www.orthodb.org/?gene=A0A8V0Z0R2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BYP8", "url": "https://www.orthodb.org/?gene=E1BYP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22958:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22958:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25329", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25329", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001385177", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385177", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16061", "url": "https://www.rhea-db.org/rhea/16061", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z0Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0R2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z0R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0R2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYP8-1", "url": "https://www.uniprot.org/uniprotkb/E1BYP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSSQVTFEVRGPSVPGEVFAICGSCSALGSWNPQAAVVLQTDDCELWKATIELPRGVPVKYRYFKGYFLEPKTIDGPCEVIVHTWETHLQPRSITPLENEMTIDDGYFGIHNGIETVDAGWLTCQTEIRLRLHYSEKSPVMISKKKFKTSRFRVKLTLEGLEKDDDDEEGQEKTSPTVPQKMANTVEFSLISNNEYKCRHSQPDCGYALQSDRWLEYTIQTMEPDNLELIFDFFEEDLSEKVVQDDEHPGHVGSACLLSSTIAESGKSAGILTLAIMGRNPRKTIGKVRVDYLIIKPIQGYTCDMKASYAKYWKPRTTLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAYVEFDVHLSKDHVPIVYHDLTCCMAMKKKLDTEPLELFEIAVKELTFDQLQLLKLAHVTALKVKDHNASFKEEENSAYETQPFPSLQRVLESVSEDVGFNIEIKWICQQKDGQWDGNLSTYFDMNLFLDIILKTVLMNAGRRRIVFSSFNADICTMVRHKQNKYPVLFLTQGESKLYPELMDLRSRTTPIAITFAQFENLLGVNVHSEDLLRNPLYIKRAISKGLVIFSWGDDANDPDNRKKLKEYGVHGLIYDRIYDSNPEQPNIFQVEQLERLKKELPELKSCVCPTVSHFKSISPCKCHHSCLEEKAVDNLQSVQMQKD", "length": 678, "header": "tr|E1BYP8-1|E1BYP8_CHICK Isoform 1 of Glycerophosphocholine phosphodiesterase GPCPD1 OS=Gallus gallus OX=9031 GN=GPCPD1 PE=3 SV=2 CANONICAL=E1BYP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z0Q7-1", "url": "https://www.uniprot.org/uniprotkb/E1BYP8/entry#A0A8V0Z0Q7-1", "sequence": { "sequence": "MPTFLGVWVVCNASQRYLCDRSEDTVVILREVFAICGSCSALGSWNPQAAVVLQTDDCELWKATIELPRGVPVKYRYFKGYFLEPKTIDGPCEVIVHTWETHLQPRSITPLENEMTIDDGYFGIHNGIETVDAGWLTCQTEIRLRLHYSEKSPVMISKKKFKTSRFRVKLTLEGLEKDDDDEEGQEKTSPTVPQKMANTVEFSLISNNEYKCRHSQPDCGYALQSDRWLEYTIQTMEPDNLELIFDFFEEDLSEKVVQDDEHPGHVGSACLLSSTIAESGKSAGILTLAIMGRNPRKTIGKVRVDYLIIKPIQGYTCDMKASYAKYWKPRTTLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAYVEFDVHLSKDHVPIVYHDLTCCMAMKKKLDTEPLELFEIAVKELTFDQLQLLKLAHVTALKVKDHNASFKEEENSAYETQPFPSLQRVLESVSEDVGFNIEIKWICQQKDGQWDGNLSTYFDMNLFLDIILKTVLMNAGRRRIVFSSFNADICTMVRHKQNKYPVLFLTQGESKLYPELMDLRSRTTPIAITFAQFENLLGVNVHSEDLLRNPLYIKRAISKGLVIFSWGDDANDPDNRKKLKEYGVHGLIYDRIYDSNPEQPNIFQVEQLERLKKELPELKSCVCPTVSHFKSISPCKCHHSCLEEKAVDNLQSVQMQKD", "length": 691, "header": "tr|A0A8V0Z0Q7-1|E1BYP8_CHICK Computationally mapped isoform of Glycerophosphocholine phosphodiesterase GPCPD1 OS=Gallus gallus OX=9031 GN=GPCPD1 PE=3 SV=1 CANONICAL=E1BYP8-1" }, "locus": { "chromosome": "3", "start_pos": 16479418, "end_pos": 16451352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041877.1", "url": "https://www.ensembl.org/id/ENSGALT00010041877.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024493.1", "url": "https://www.ensembl.org/id/ENSGALP00010024493.1" } ] } }, { "isoform_ac": "A0A8V0Z0R2-1", "url": "https://www.uniprot.org/uniprotkb/E1BYP8/entry#A0A8V0Z0R2-1", "sequence": { "sequence": "MTSSQVTFEVRGPSVPGEVFAICGSCSALGSWNPQAAVVLQTDDCELWKATIELPRGVPVKYRYFKGYFLEPKTIDGPCEVIVHTWETHLQPRSITPLENEMTIDDGYFGIHNGIETVDAGWLTCQTEIRLRLHYSEKSPVMISKKKFKTSRFRVKLTLEGLEKDDDDEEGQEKTSPTVPQKMANTVEFSLISNNEYKCRHSQPDCGYALQSDRWLEYTIQTMEPDNLELIFDFFEEDLSEKVVQDDEHPGHVGSACLLSSTIAESGKSAGILTLAIMGRNPRKTIGKVRVDYLIIKPIQGYTCDMKASYAKYWKPRTTLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAYVEFDVHLSKDHVPIVYHDLTCCMAMKKKLDTEPLELFEIAVKELTFDQLQLLKLAHVTALKVKDHNASFKEEENSAYETQPFPSLQRVLESVSEDVGFNIEIKWICQQKDGQWDGNLSTYFDMNLFLDIILKTVLMNAGRRRIVFSSFNADICTMVRHKQNKYPVLFLTQGESKLYPELMDLRSRTTPIAITFAQFENLLGVNVHSEDLLRNPLYIKRAISKGLVIFSWGDDANDPDNRKKLKEYGVHGLIYDSLPCKDEQKCCCEDERKTVS", "length": 630, "header": "tr|A0A8V0Z0R2-1|E1BYP8_CHICK Computationally mapped isoform of Glycerophosphocholine phosphodiesterase GPCPD1 OS=Gallus gallus OX=9031 GN=GPCPD1 PE=3 SV=1 CANONICAL=E1BYP8-1" }, "locus": { "chromosome": "3", "start_pos": 16484248, "end_pos": 16454196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041884.1", "url": "https://www.ensembl.org/id/ENSGALT00010041884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024498.1", "url": "https://www.ensembl.org/id/ENSGALP00010024498.1" } ] } }, { "isoform_ac": "E1BYP8-1", "url": "https://www.uniprot.org/uniprotkb/E1BYP8/entry#E1BYP8-1", "sequence": { "sequence": "MTSSQVTFEVRGPSVPGEVFAICGSCSALGSWNPQAAVVLQTDDCELWKATIELPRGVPVKYRYFKGYFLEPKTIDGPCEVIVHTWETHLQPRSITPLENEMTIDDGYFGIHNGIETVDAGWLTCQTEIRLRLHYSEKSPVMISKKKFKTSRFRVKLTLEGLEKDDDDEEGQEKTSPTVPQKMANTVEFSLISNNEYKCRHSQPDCGYALQSDRWLEYTIQTMEPDNLELIFDFFEEDLSEKVVQDDEHPGHVGSACLLSSTIAESGKSAGILTLAIMGRNPRKTIGKVRVDYLIIKPIQGYTCDMKASYAKYWKPRTTLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAYVEFDVHLSKDHVPIVYHDLTCCMAMKKKLDTEPLELFEIAVKELTFDQLQLLKLAHVTALKVKDHNASFKEEENSAYETQPFPSLQRVLESVSEDVGFNIEIKWICQQKDGQWDGNLSTYFDMNLFLDIILKTVLMNAGRRRIVFSSFNADICTMVRHKQNKYPVLFLTQGESKLYPELMDLRSRTTPIAITFAQFENLLGVNVHSEDLLRNPLYIKRAISKGLVIFSWGDDANDPDNRKKLKEYGVHGLIYDRIYDSNPEQPNIFQVEQLERLKKELPELKSCVCPTVSHFKSISPCKCHHSCLEEKAVDNLQSVQMQKD", "length": 678, "header": "tr|E1BYP8-1|E1BYP8_CHICK Isoform 1 of Glycerophosphocholine phosphodiesterase GPCPD1 OS=Gallus gallus OX=9031 GN=GPCPD1 PE=3 SV=2 CANONICAL=E1BYP8-1" }, "locus": { "chromosome": "3", "start_pos": 16484248, "end_pos": 16451352, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041892.1", "url": "https://www.ensembl.org/id/ENSGALT00010041892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024504.1", "url": "https://www.ensembl.org/id/ENSGALP00010024504.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 645, "start_aa": "Thr", "end_pos": 645, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr645", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N041-1", "protein_name": "Glycerophosphocholine phosphodiesterase GPCPD1", "gene_name": "GPCPD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTPSQVTFEIRGTLLPGEVFAICGSCDALGNWNPQKAVALLPENETGESMLWKATIVLSRGVSVQYRYFKGCFLEPKTIGGPCQVIVHKWETHLQPRSITPLESEIIIDDGQFGIHNGIETLDSGWLTCQTEIRLRLHYSEKPPVSITKKKFKKSRFRVKLTLEGLEEDDDDRVSPTVLHKMSNSLEISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFEEDLSEHVVQGDAFPGHVGTACLLSSTIAESGKSAGILTLPIMSRNSRKTIGKVRVDYIIIKPLPGYSCDMKSSFSKYWKPRIPLDVGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTCCLTMKKKFDADPVELFEIPVKELTFDQLQLLKLTHVTALKSKDLKESMVEEENSFSENQPFPSLKMVLESLPEDVGFNIEIKWICQQRDGMWDGNLSTYFDMNLFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSDIYPELMDLRSRTTPIAMSFAQFENLLGINAHTEDLLRNPSYIQEAKAKGLVIFCWGDDTNDPENRKKLKEFGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQELPELKSCLCPTVSRFVPSSLCGEPDIHVDANGIDNVESA", "length": 672 }, "evidence": [ { "id": "E1BYP8", "url": "https://omabrowser.org/oma/group/E1BYP8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q1LVM1-1", "protein_name": "3.1.4.2", "gene_name": "gpcpd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSTKVTLTVRGSTALGEVIAVVGSCETLGSWCQQKAVTLQPAEEDGTLWRTTIHVPRGAETKYRYFKAFILESKNAGGPCQVIVNRWETHQLPRSLSPSEPELVVDDGHFGVHDGAECVDSGWLTCQTEIRLRLHYSVKPPVSITKKKFKTSRFRLKLMLEGVEEEEEEEESPSSWHKMTTTLEMSMISDDGYKSRHSQPECGYALEPSRWTEYTIHTMDPDNLVLTFEFFEEDLSETVVQGDAHPGHVGTACLLSSSFVESGKDLGVVTLPIMSRNSRQTLGKVRVDYLVTRPIQGLQCDMSRSFTKYWRKRSALDVGHRGAGSTHAAKHHKIRENTIASFLSAANHGAAYVEFDVHLSKDLVPVVYHDLTCCISTKKKNDKTSMLLFEVPVKDLTFDQLQLLKLAHTTALDTHDHKDLQDEEEYIDEHQPFPSLPQIFQSVPENVGFNIELKWISQFKDGSWDANLSTYFNMNQFLDIILTCVLQNAGNRRIIFSCFDPDVCTMVRQKQNKYPILFLTQGVTQLYPELMDIRCQSTKIAMSFAQSENILGISAHTDELLKNMEFIGEAQSKGLVVFCWGDYNNDHENRRKLREHGIDGLIYDRICEDKLEQSNIFKMEEQGGNLKEVIQTCACSTYSIPCSSFPCPGRPSETNGESDSGLSSS", "length": 666 }, "evidence": [ { "id": "E1BYP8", "url": "https://omabrowser.org/oma/group/E1BYP8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80VJ4-1", "protein_name": "Glycerophosphocholine phosphodiesterase GPCPD1", "gene_name": "Gpcpd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTPSQVTFEIRGTLLPGEVFAMCGNCDALGNWSPQNAVPLTESETGESVWKAVIVLSRGMSVKYRYFRGCFLEPKTIGGPCQVIVHKWETHLQPRSITPLENEIIIDDGQFGIHNGVETLDSGWLTCQTEIRLRLHFSEKPPVSITKKKFKKSRFRVKLTLEGLEEDDDDDDKASPTVLHKMSNSLEISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFEEDLSEHVVQGDVLPGHVGTACLLSSTIAESERSAGILTLPIMSRSSRKTIGKVRVDFIIIKPLPGYSCSMQSSFSKYWKPRIPLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAFVEFDVHLSKDLVPVVYHDLTCCLTMKRKYEADPVELFEIPVKELTFDQLQLLKLSHVTALKTKDQKQCMAEEENSFSENQPFPSLKMVLESLPENVGFNIEIKWICQHRDGVWDGNLSTYFDMNAFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSDIYPELMDLRSRTTPIAMSFAQFENILGINAHTEDLLRNPSYVQEAKDKGLVIFCWGDDTNDPENRRKLKEFGVNGLIYDRIYDWMPEQPNIFQVEQLERLKRELPELKNCLCPTVSHFIPPSFCMESKIHVDANGIDNVENA", "length": 672 }, "evidence": [ { "id": "E1BYP8", "url": "https://omabrowser.org/oma/group/E1BYP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0L9-1", "protein_name": "Glycerophosphocholine phosphodiesterase GPCPD1", "gene_name": "Gpcpd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPSQVTFEIRGTLLPGEVFAICGSCDALGNWNPQNAVALINENETGDSVLWKAVIALNRGVSVKYRYFRGCFLEPKTIGGPCQVIVHKWETHLQPRSITPLESEIIIDDGQFGIHNGVETLDSGWLTCQTEIRLRLHFSEKPPVSISKKKFKKSRFRVKLTLEGLEEDEDDDDDKVSPTVLHKMSNSLEISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFEEDLSEHVVQGDVLPGHVGTACLLSSTIAESGRSAGILTLPIMSRNSRKTIGKVRVDFIIIKPLPGYSCSMQSSFSKYWKPRIPLDVGHRGAGNSTTTAKLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTCCLTMKRKYEADPVELFEIPVKELTFDQLQLLKLSHVTALKTKDRKQSLYEEENFFSENQPFPSLKMVLESLPENVGFNIEIKWICQHRDGVWDGNLSTYFDMNVFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSDIYPELMDLRSRTTPIAMSFAQFENILGINAHTEDLLRNPSYVQEAKAKGLVIFCWGDDTNDPENRRKLKEFGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQELPELKNCLCPTVSHFIPSSFCVEPDIHVDANGIDSVENA", "length": 675 }, "evidence": [ { "id": "E1BYP8", "url": "https://omabrowser.org/oma/group/E1BYP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NPB8-1", "protein_name": "Glycerophosphocholine phosphodiesterase GPCPD1", "gene_name": "GPCPD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPSQVAFEIRGTLLPGEVFAICGSCDALGNWNPQNAVALLPENDTGESMLWKATIVLSRGVSVQYRYFKGYFLEPKTIGGPCQVIVHKWETHLQPRSITPLESEIIIDDGQFGIHNGVETLDSGWLTCQTEIRLRLHYSEKPPVSITKKKLKKSRFRVKLTLEGLEEDDDDRVSPTVLHKMSNSLEISLISDNEFKCRHSQPECGYGLQPDRWTEYSIQTMEPDNLELIFDFFEEDLSEHVVQGDALPGHVGTACLLSSTIAESGKSAGILTLPIMSRNSRKTIGKVRVDYIIIKPLPGYSCDMKSSFSKYWKPRIPLDVGHRGAGNSTTTAQLAKVQENTIASLRNAASHGAAFVEFDVHLSKDFVPVVYHDLTCCLTMKKKFDADPVELFEIPVKELTFDQLQLLKLTHVTALKSKDRKESVVQEENSFSENQPFPSLKMVLESLPEDVGFNIEIKWICQQRDGMWDGNLSTYFDMNLFLDIILKTVLENSGKRRIVFSSFDADICTMVRQKQNKYPILFLTQGKSEIYPELMDLRSRTTPIAMSFAQFENLLGINVHTEDLLRNPSYIQEAKAKGLVIFCWGDDTNDPENRRKLKELGVNGLIYDRIYDWMPEQPNIFQVEQLERLKQELPELKSCLCPTVSRFVPSSLCGESDIHVDANGIDNVENA", "length": 672 }, "evidence": [ { "id": "E1BYP8", "url": "https://omabrowser.org/oma/group/E1BYP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQU3-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHNWLASHNGDEDAMAAPSSCPASSENGSRLESRRIFGDITTNRLWTFRVLMNQDLAPNEQLAIVGNCEALGNWQHSGAAILSKNEEDNEYSNLWTGEIYIPRHCDTEYRYMVCAVDPGTEQLIVRRWETQLQPRIVKELDEQPAKNQSDIFGSFNGQEKVDRGWLTKETLVQLKFFYAPFTFKQRMKRRHIQVKVTPMNLSIPSAGCDTMLPSSPMEDSLSNDTHDTKENGGESSTAFAFSEVVTLSADECEIRSQEQFGTGCGPTDLVIFHLTVGDFENTAYLIDLYSYSSRVAKEDGPPNHLGYHYVLPNLFKRSEGNLELPITCAKGHRPLGMMRLGYLIVKPSSLCALMDMSVSYARYWNSKWTGLDVGHRGSGTSFKAKDAVIRENTITSLKNAAEHGADMVEFDVQLSKDLVPVVYHDFMIYVSLKSKCSLQEHDFLALPMRELSLEQLKKLKVYHIAEGLSRETRSFHNDDCLEHQPFPQLCDVLDALDVHVGFNIEIKWSQRLEDGKMEEEFEHVVDRNLYIDCILDVILRKAGNRRIVLSCFDPDICTILRFKQNRYPVMFLTLGRTTKYQKYMDPRGNSMELAVWHAVAMEFLGVVAHTEDLLRDPSQVNLAKERGLVLFCWGDDNNSKDTIKLLKELGLHAIIYDKMDVLTTKEVKQSVFHLQAKDSQKELLKLQALEMGHVWHTSADGNEEQQA", "length": 707 }, "evidence": [ { "id": "E1BYP8", "url": "https://omabrowser.org/oma/group/E1BYP8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycerophospholipid catabolic process", "id": "GO:0046475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046475", "evidence": [ { "database": "UniProtKB", "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "starch binding", "id": "GO:2001070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001070", "evidence": [ { "database": "UniProtKB", "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ], "pmid": "" }, { "name": "glycerophosphocholine phosphodiesterase activity", "id": "GO:0047389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047389", "evidence": [ { "database": "UniProtKB", "id": "E1BYP8", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16061", "name": "", "equation": "sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q3KTM2-1", "E1BYP8-1" ], "evidence": [ { "id": "16061", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16061" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "E1BYP8", "gene_name": "GPCPD1", "activity": [ { "ec_number": "3.1.4.2", "activity": "sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+).", "evidence": [ { "id": "E1BYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ] }, { "ec_number": "3.1.4.2", "activity": "", "evidence": [ { "id": "E1BYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYP8" } ] } ] }, { "uniprot_ac": "Q3KTM2", "gene_name": "GDPD5", "activity": [ { "ec_number": "3.1.4.-", "activity": "", "evidence": [ { "id": "Q3KTM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3KTM2" } ] }, { "ec_number": "3.1.4.2", "activity": "sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+).", "evidence": [ { "id": "Q3KTM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q3KTM2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.4.2", "ec_name": "sn-glycerol 3-phosphocholine + H2O = sn-glycerol 3-phosphate + choline + H(+).", "evidence": [ { "id": "3.1.4.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.4.2" }, { "id": "3.1.4.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.4.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 645 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 473, "end_pos": 475 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BV82-1", "uniprot_ac": "E1BV82", "uniprot_id": "E1BV82_CHICK", "mass": { "chemical_mass": 39783.0, "monoisotopic_mass": 39783.0 }, "refseq": { "ac": "XP_004941244", "name": "ras association domain-containing protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941244" }, "gene_names": [ { "name": "RASSF6", "type": "recommended", "evidence": [ { "id": "E1BV82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BV82" } ] }, { "name": "RASSF6", "type": "synonym", "evidence": [ { "id": "XP_004941244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941244" } ] } ], "protein_names": [ { "name": "Ras association domain family member 6", "type": "synonym", "evidence": [ { "id": "E1BV82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BV82/entry#names_and_taxonomy" } ] }, { "name": "ras association domain-containing protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004941244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941244" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941244" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BV82", "url": "https://www.uniprot.org/uniprotkb/E1BV82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASSF6", "url": "https://www.uniprot.org/uniprotkb/E1BV82", "locus": { "chromosome": "4", "start_pos": 50380150, "end_pos": 50408648, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005111", "url": "https://www.ensembl.org/id/ENSGALG00010005111" } ] } } ], "crossref": [ { "id": "E1BV82", "url": "https://alphafold.ebi.ac.uk/entry/E1BV82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011664", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011664", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422653", "url": "https://www.ncbi.nlm.nih.gov/gene/422653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422653", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422653", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIFVNER", "url": "https://omabrowser.org/oma/group/WIFVNER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XPE7", "url": "https://www.orthodb.org/?gene=A0A8V0XPE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BV82", "url": "https://www.orthodb.org/?gene=E1BV82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941244", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XPE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XPE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BV82", "url": "https://www.uniprot.org/uniprotkb/E1BV82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BV82-1", "url": "https://www.uniprot.org/uniprotkb/E1BV82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKATMKAHHLPSFAINEEKFITREQLHSLLKTYNSYYSDQENLQLSYDQREGGKPFIEGILSIFWGVRHPIRLQIQDEKQIPSFVTLKSTENVGLFPSKRGMTRWGEFDDLHHISGETLKSTEEKLNSEKSYSYYESSTLKSKSEQEHDCATLPRAVSSTAAVRKRTKFSMIARTEVETHRFSINGHFYNYETSVFTPASGSETKIRINSHMRTREVIEQLLRKFKIENSPHDFALYIIHVSGEKKQLRSGDIPLLHRLLQGPSEEAAKFFLMDRDVEEVSSDVAQYIQFHLPFLESILQRIKEEEEQEIQQTIAKYFKEKHAICQHLQNRTFKKTETTV", "length": 341, "header": "tr|E1BV82-1|E1BV82_CHICK Isoform 1 of Ras association domain family member 6 OS=Gallus gallus OX=9031 GN=RASSF6 PE=4 SV=2 CANONICAL=E1BV82-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XPE7-1", "url": "https://www.uniprot.org/uniprotkb/E1BV82/entry#A0A8V0XPE7-1", "sequence": { "sequence": "MKKATMKAHHLPSFAINEEKFITREQLHSLLKTYNSYYSDQENLQLSYDQREGGKPFIEGILSIFWGVRHPIRLQIQDEKQIPSFVTLKSTENVGLFPSKRGMTRWGEFDDLHHISGETLKSTEEKLNSEKSYSYYESSTLKSKSEQEHDCATLPRAVSSTAAVRKRTKFSMIARTEVETHRFSINGHFYNYETSVFTPASGSETKIRINSHMRTREVIEQLLRKFKIENSPHDFALYIIHVSGEKKQLRSGDIPLLHRLLQGPSEEAAKFFLMDRDVEEVAQYIQFHLPFLESILQRIKEEEEQEIQQTIAKYFKEKHAICQHLQNRTFKKTETTV", "length": 337, "header": "tr|A0A8V0XPE7-1|E1BV82_CHICK Computationally mapped isoform of Ras association domain family member 6 OS=Gallus gallus OX=9031 GN=RASSF6 PE=4 SV=1 CANONICAL=E1BV82-1" }, "locus": { "chromosome": "4", "start_pos": 50397029, "end_pos": 50382412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012017.1", "url": "https://www.ensembl.org/id/ENSGALT00010012017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006710.1", "url": "https://www.ensembl.org/id/ENSGALP00010006710.1" } ] } }, { "isoform_ac": "E1BV82-1", "url": "https://www.uniprot.org/uniprotkb/E1BV82/entry#E1BV82-1", "sequence": { "sequence": "MKKATMKAHHLPSFAINEEKFITREQLHSLLKTYNSYYSDQENLQLSYDQREGGKPFIEGILSIFWGVRHPIRLQIQDEKQIPSFVTLKSTENVGLFPSKRGMTRWGEFDDLHHISGETLKSTEEKLNSEKSYSYYESSTLKSKSEQEHDCATLPRAVSSTAAVRKRTKFSMIARTEVETHRFSINGHFYNYETSVFTPASGSETKIRINSHMRTREVIEQLLRKFKIENSPHDFALYIIHVSGEKKQLRSGDIPLLHRLLQGPSEEAAKFFLMDRDVEEVSSDVAQYIQFHLPFLESILQRIKEEEEQEIQQTIAKYFKEKHAICQHLQNRTFKKTETTV", "length": 341, "header": "tr|E1BV82-1|E1BV82_CHICK Isoform 1 of Ras association domain family member 6 OS=Gallus gallus OX=9031 GN=RASSF6 PE=4 SV=2 CANONICAL=E1BV82-1" }, "locus": { "chromosome": "4", "start_pos": 50397029, "end_pos": 50382412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012019.1", "url": "https://www.ensembl.org/id/ENSGALT00010012019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006712.1", "url": "https://www.ensembl.org/id/ENSGALP00010006712.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422653", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422653", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MDS2-1", "protein_name": "Ras association domain family member 6", "gene_name": "RASSF6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMAHQFSSWIFINERTFITGEQLNSLLKTYNFFYRNQKNLHILYGQTEDGKLIVEGTLDIFWGVKRPIQLKIQDEKQIPSFSVLESPEAFSKRGMTRWGQFDDLYRISDLDRDQIPVTGGTGSQEDYLSYHSSTLKPHANEEPESPLLYRTMSEATLVRKRMTPLTMDRKDRQKHRASINGHFYNHETSIFTPVFGSETKVRVNSNMRTEEVIKQILQKFKIENSAQDFALYIIFATGEQKRLKKTDIPLLHRLLQGPSKTNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRTVAKFSTEKAIILKYLQSKRVIKTETTV", "length": 335 }, "evidence": [ { "id": "E1BV82", "url": "https://omabrowser.org/oma/group/E1BV82/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RUL8-1", "protein_name": "Ras association domain family member 6", "gene_name": "RASSF6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTMMAHEASSWIFINERTFITREQLNSLLKTYNIFYRNQENLHILYGQTEDGKLIVEGLLDIFWGVKRPLQLKIQDEKQIPSFTALKSPDVFSKRGMTRWGEFDDLHRISDLDRTQIPVSEATNSQEDYLSYQCSTLKPHTDEEPESPLLYRTMSEAALVRKRMKPPMMDRKARQKHRASINGHIYNHETSIFTPAFGSETKVRINSDMRTEEVIKQILQKFKIENSAQDFALYIIFSTGEQRRLKKTDIPLLHRLLQGPSKKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRTIIKFRTEKAIILKYLQSKRVIKTETTV", "length": 337 }, "evidence": [ { "id": "E1BV82", "url": "https://omabrowser.org/oma/group/E1BV82/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4QR82-1", "protein_name": "Ras association domain-containing protein 6", "gene_name": "Rassf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTMDHRFPSRIFVNERTSITREQLNSLLETYNVFYENQKNLHILYGQTEDGQLIVEGMLDIFWGVKRPIQLKIQDEKQISSFDLLKSPETFSSKGRMTRWGEFDDLYRISEMDKTQALAPEARHTPEDYLSCYSVLKQCADEEPESPLLYRTVSEAALVRKRMRAPEMYRKDRMGTLAKHRASINGHVYDHETSIFTPTFGSETKVRANSIMKTEEVIKQLLQKFKIENSPRDFALYIIFGTGEKRKLKKTDVPLLQRLIQGPSKSNARIFLMDKDAEEISSDVAPYINFHFSFLKSILQRLDEEEKMEIERIMAKFNTERAFILKCLQSKRAAKTETTV", "length": 341 }, "evidence": [ { "id": "E1BV82", "url": "https://omabrowser.org/oma/group/E1BV82/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZTQ3-1", "protein_name": "Ras association domain-containing protein 6", "gene_name": "RASSF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLWEETGAAPAPARASDLPYRISSDHLKKEEKMTMMAHQYPSWIFINEKTFITREQLNSLLKTYNIFYENQKNLHILYGETEDGKLIVEGMLDIFWGVKRPIQLKIQDEKPFSSFTSMKSSDVFSSKGMTRWGEFDDLYRISELDRTQIPMSEKRNSQEDYLSYHSNTLKPHAKDEPDSPVLYRTMSEAALVRKRMKPLMMDRKERQKNRASINGHFYNHETSIFIPAFESETKVRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQRRLKKTDIPLLQRLLQGPSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKFNKEKAIILKCLQNKLVIKTETTV", "length": 369 }, "evidence": [ { "id": "E1BV82", "url": "https://omabrowser.org/oma/group/E1BV82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80UQ2-1", "protein_name": "Ras association domain-containing protein 6", "gene_name": "Rassf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAMDHQFPSWIVVNESTSISREQLNYLLETYNVFYENQKNLHILYGQTEDGQLIVEGMLDIFWGVKRPIQLKIQDEKQISSFDLLNTPETFSSKGRMTRWGEFDDLYRISELDRTHVLASEARHSPEDYLSYHSTLTPYADEEPESPLLYRTMSEAALVRKRMRAPEMYRKDRMGVLSNHRASINGHVYDHETSIFTPTFGSETKVRANSIMRTEEVIKQLLQKFKIENSPRDFALYIIFGTGEQRKLKKTDVPLLQRLLQGPSKSNARIFLMDKDAEEISRDVAPYINFHFSFLESILQRLDEEEKMEIERIMAKFNTERAFILKCLQSKQAAKTETTV", "length": 341 }, "evidence": [ { "id": "E1BV82", "url": "https://omabrowser.org/oma/group/E1BV82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BV82", "url": "https://www.uniprot.org/uniprotkb/E1BV82" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "E1BV82", "url": "https://www.uniprot.org/uniprotkb/E1BV82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BV82-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 341, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BV82-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BV82" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXT5-1", "uniprot_ac": "E1BXT5", "uniprot_id": "E1BXT5_CHICK", "mass": { "chemical_mass": 19283.0, "monoisotopic_mass": 19283.0 }, "refseq": { "ac": "XP_423597", "name": "EKC/KEOPS complex subunit TPRKB", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423597" }, "gene_names": [ { "name": "TPRKB", "type": "recommended", "evidence": [ { "id": "E1BXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXT5" } ] }, { "name": "TPRKB", "type": "synonym", "evidence": [ { "id": "XP_423597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423597" } ] } ], "protein_names": [ { "name": "EKC/KEOPS complex subunit TPRKB", "type": "recommended", "evidence": [ { "id": "E1BXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXT5/entry#names_and_taxonomy" } ] }, { "name": "EKC/KEOPS complex subunit TPRKB", "type": "synonym", "evidence": [ { "id": "XP_423597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423597" } ] }, { "name": "EKC/KEOPS complex subunit Tprkb", "type": "synonym", "evidence": [ { "id": "E1BXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXT5/entry#names_and_taxonomy" } ] }, { "name": "PRPK-binding protein", "type": "synonym", "evidence": [ { "id": "E1BXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXT5/entry#names_and_taxonomy" } ] }, { "name": "TP53RK-binding protein", "type": "synonym", "evidence": [ { "id": "E1BXT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXT5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_423597.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423597" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXT5", "url": "https://www.uniprot.org/uniprotkb/E1BXT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TPRKB", "url": "https://www.uniprot.org/uniprotkb/E1BXT5", "locus": { "chromosome": "1", "start_pos": 15890576, "end_pos": 15884069, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008199", "url": "https://www.ensembl.org/id/ENSGALG00010008199" } ] } } ], "crossref": [ { "id": "E1BXT5", "url": "https://alphafold.ebi.ac.uk/entry/E1BXT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013018", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013018", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425906", "url": "https://www.ncbi.nlm.nih.gov/gene/425906", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425906", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425906", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVCRMST", "url": "https://omabrowser.org/oma/group/IVCRMST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XWU3", "url": "https://www.orthodb.org/?gene=A0A8V0XWU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXT5", "url": "https://www.orthodb.org/?gene=E1BXT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15840", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15840", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15840:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15840:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_423597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423597", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XWU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXT5", "url": "https://www.uniprot.org/uniprotkb/E1BXT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BXT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLTHPLELFPERSVTLLLFNRVQNAAALRKKAMEGSIEGALINPAMIVDPFQVLVAANKAVHLHKIGKMKTRTLNAEIIFNLSPNNNISDAFKKFGISDSDTAVLIVLVVDREKMVNLEDIASQVEGQQVSLDELPQLTDIAKVKKIYKITPQEEKIGTLLDGIICRISTKDV", "length": 174, "header": "tr|E1BXT5-1|E1BXT5_CHICK Isoform 1 of EKC/KEOPS complex subunit TPRKB OS=Gallus gallus OX=9031 GN=TPRKB PE=1 SV=1 CANONICAL=E1BXT5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XWU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BXT5/entry#A0A8V0XWU3-1", "sequence": { "sequence": "MHLTHPLELFPERSVTLLLFNRVQNAAALRKKAMEGSIEGALINPAMIVDPFQVLVAANKAVHLHKIGKMKTRTLNAEIIFNLSPNNNISDAFKKFGISDSDTAVLIVLVVDREKMVNLEDIASQVEGQQVSLDELPQLTDIAKVKKIYKITPQEEKIGTLLDEKGMGWYTMAPTDGCSVGQQLQRCTEQQIRSG", "length": 195, "header": "tr|A0A8V0XWU3-1|E1BXT5_CHICK Computationally mapped isoform of EKC/KEOPS complex subunit TPRKB OS=Gallus gallus OX=9031 GN=TPRKB PE=1 SV=1 CANONICAL=E1BXT5-1" }, "locus": { "chromosome": "1", "start_pos": 15887563, "end_pos": 15884245, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019614.1", "url": "https://www.ensembl.org/id/ENSGALT00010019614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011162.1", "url": "https://www.ensembl.org/id/ENSGALP00010011162.1" } ] } }, { "isoform_ac": "E1BXT5-1", "url": "https://www.uniprot.org/uniprotkb/E1BXT5/entry#E1BXT5-1", "sequence": { "sequence": "MHLTHPLELFPERSVTLLLFNRVQNAAALRKKAMEGSIEGALINPAMIVDPFQVLVAANKAVHLHKIGKMKTRTLNAEIIFNLSPNNNISDAFKKFGISDSDTAVLIVLVVDREKMVNLEDIASQVEGQQVSLDELPQLTDIAKVKKIYKITPQEEKIGTLLDGIICRISTKDV", "length": 174, "header": "tr|E1BXT5-1|E1BXT5_CHICK Isoform 1 of EKC/KEOPS complex subunit TPRKB OS=Gallus gallus OX=9031 GN=TPRKB PE=1 SV=1 CANONICAL=E1BXT5-1" }, "locus": { "chromosome": "1", "start_pos": 15886933, "end_pos": 15884245, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019617.1", "url": "https://www.ensembl.org/id/ENSGALT00010019617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011165.1", "url": "https://www.ensembl.org/id/ENSGALP00010011165.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425906", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7H8Z7-1", "protein_name": "EKC/KEOPS complex subunit TPRKB", "gene_name": "Tprkb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMGDTSGSGEACFRGDDLLRRTGDWSVVLVYEMQLSQQLDLFPECRVTLLLFKDVKNAGDLKKKAMNGSINCSLINPNVIIDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESATSVLIVYTEEGEKQINQEHLVSQVEGQQVPLECLPEITKLSEVKKILHKRKELGPTSLWNVIWNRVTEL", "length": 203 }, "evidence": [ { "id": "E1BXT5", "url": "https://omabrowser.org/oma/group/E1BXT5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q03705-1", "protein_name": "EKC/KEOPS complex subunit CGI121", "gene_name": "CGI121", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVVSIIPQFPDIKVSLALFEQVKNAKEIRSKMSELSTSFAFIDPRLVCSGEQMYSAIYKTLIEVKYNKMRTRNLNSECVLCLSPTSNISDAFLKFGIKDDSSQLICLKFHTNTDDVDKEQLRTIMTSIVKGQEIEFNDDNLSRFYDEALIRKIYKLSDDFKPQDVNGLSRALVDAIQLRGV", "length": 181 }, "evidence": [ { "id": "E1BXT5", "url": "https://omabrowser.org/oma/group/E1BXT5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5PQR8-1", "protein_name": "EKC/KEOPS complex subunit Tprkb", "gene_name": "Tprkb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLTQQLDLFPECKVTLLLFKDVKNAGDLRKKAMEGSIDGSLINANVIVDPFQILVAANKAVHLHKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISESNTSVLIVYVEDGDKQVHQEHLVSQVEGQQVPLESLPEITRLSEVRKVCSTQPEEVSR", "length": 158 }, "evidence": [ { "id": "E1BXT5", "url": "https://omabrowser.org/oma/group/E1BXT5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8QZZ7-1", "protein_name": "EKC/KEOPS complex subunit Tprkb", "gene_name": "Tprkb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLSQQLDLFPECRVTLLLFKDVKNAGDLRKKAMEGSIDGSLINPNVIVDPFQILVAANKAVHLHRLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISETNTSVLIVYIEDGSKQVPQEHLVSQVEGQQVPLESLPEITRLSEVKKIYKLSSQEERIGTLLDAIICRMSTKDVL", "length": 175 }, "evidence": [ { "id": "E1BXT5", "url": "https://omabrowser.org/oma/group/E1BXT5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3C4-1", "protein_name": "EKC/KEOPS complex subunit TPRKB", "gene_name": "TPRKB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQLTHQLDLFPECRVTLLLFKDVKNAGDLRRKAMEGTIDGSLINPTVIVDPFQILVAANKAVHLYKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISANDTSILIVYIEEGEKQINQEYLISQVEGHQVSLKNLPEIMNITEVKKIYKLSSQEESIGTLLDAIICRMSTKDVL", "length": 175 }, "evidence": [ { "id": "E1BXT5", "url": "https://omabrowser.org/oma/group/E1BXT5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BXT5", "url": "https://www.uniprot.org/uniprotkb/E1BXT5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BXT5", "url": "https://www.uniprot.org/uniprotkb/E1BXT5" } ], "pmid": "" }, { "name": "EKC/KEOPS complex", "id": "GO:0000408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000408", "evidence": [ { "database": "UniProtKB", "id": "E1BXT5", "url": "https://www.uniprot.org/uniprotkb/E1BXT5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BXT5", "url": "https://www.uniprot.org/uniprotkb/E1BXT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA threonylcarbamoyladenosine modification", "id": "GO:0002949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002949", "evidence": [ { "database": "UniProtKB", "id": "E1BXT5", "url": "https://www.uniprot.org/uniprotkb/E1BXT5" } ], "pmid": "" }, { "name": "tRNA processing", "id": 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"start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSP5-1", "uniprot_ac": "E1BSP5", "uniprot_id": "E1BSP5_CHICK", "mass": { "chemical_mass": 53875.0, "monoisotopic_mass": 53875.0 }, "refseq": { "ac": "XP_004935238", "name": "uncharacterized protein LOC420992 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935238" }, "gene_names": [ { "name": "LOC420992", "type": "recommended", "evidence": [ { "id": "E1BSP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSP5" } ] }, { "name": "LOC420992", "type": "synonym", "evidence": [ { "id": "XP_004935238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935238" } ] } ], "protein_names": [ { "name": "U1-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "E1BSP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSP5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC420992 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004935238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935238" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935238" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSP5", "url": "https://www.uniprot.org/uniprotkb/E1BSP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC420992", "url": "https://www.uniprot.org/uniprotkb/E1BSP5", "locus": {} } ], "crossref": [ { "id": "E1BSP5", "url": "https://alphafold.ebi.ac.uk/entry/E1BSP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013430", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013430", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420992", "url": "https://www.ncbi.nlm.nih.gov/gene/420992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420992", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNICKIY", "url": "https://omabrowser.org/oma/group/CNICKIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSP5", "url": "https://www.orthodb.org/?gene=E1BSP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45762", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45762", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45762:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45762:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004935238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U919", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U919", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U919-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U919-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XXH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5S1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5S1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSP5", "url": "https://www.uniprot.org/uniprotkb/E1BSP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSP5-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPEAEVKKQVNPFYCNICKIWCASALNLQTHFLGFKHKKVEEALKAHGIVKTASGTGDQVKAPVKLPGYVQTKPERYHGQTLEEQLNTCKDSEPALGLNYIIEYRSKDNFPFLYECQLCHCKTGLSNMFMHVCGSKHRLAYLKQHYPEIAESDEVKGKGSELNRKVRQVALTIEKKEGRKQLKVVIEAPVIRKRWQEYPNADDSPSKAKVQHVDTSLSNEEGIDCKNKDGKLRDPIQEEKSVQEEQENCQKEQAIPDEKVETNKAVEGTKGNLTEESSSSEKCETNIQLEEENEEVEQTSAAAAEEFTSQEELLSYLQSFEILNEDDAAFILKVTQTLTDALVEYRQQAASKKDLLDNERNGEEALERSTEQSELTSADISDSDTDYSCSRSAKKSLSINEEDELQNFSTGSLDTAYENNITTEFLNSVRNMNVEEVTATLHKIAATNPAFRGMDIPNVVKILTESGTLRRPSNGSTH", "length": 479, "header": "tr|E1BSP5-1|E1BSP5_CHICK Isoform 1 of U1-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420992 PE=4 SV=5 CANONICAL=E1BSP5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U919-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP5/entry#A0A3Q2U919-1", "sequence": { "sequence": "MWTEEISDWGGDSCRAFKTVKTASGTGDQVKAPVKLPGYVQTKPERYHGQTLEEQLNTCKDSEPALGLNYIIEYRSKDNFPFLYECQLCHCKTGLSNMFMHVCGSKHRLAYLKQHYPEIAESDEVKGKGSELNRKVRQVALTIEKKEGRKQLKVVIEAPVIRKRWQEYPNADDSPSKAKVQHVDTSLSNEEGIDCKNKDGKLRDPIQEEKSVQEEQENCQKEQAIPDEKVETNKAVEGTKGNLTEESSSSEKCETNIQLEEENEEVEQTSAAAAEEFTSQEELLSYLQSFEILNEDDAAFILKVTQTLTDALVEYRQQAASKKDLLDNERNGEEALERSTEQSELTSADISDSDTDYSCSRSAKKSLSINEEDELQNFSTGSLDTAYENNITTEFLNSVRNMNVEEVTATLHKIAATNPAFRGMDIPNVVKILTESGTLRRPSNGSTH", "length": 448, "header": "tr|A0A3Q2U919-1|A0A3Q2U919_CHICK Computationally mapped isoform of U1-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420992 PE=4 SV=1 CANONICAL=E1BSP5-1" }, "locus": { "chromosome": "2", "start_pos": 88736634, "end_pos": 88719615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019839.1", "url": "https://www.ensembl.org/id/ENSGALT00010019839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011387.1", "url": "https://www.ensembl.org/id/ENSGALP00010011387.1" } ] } }, { "isoform_ac": "A0A8V0XXG9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP5/entry#A0A8V0XXG9-1", "sequence": { "sequence": "MDPEAEVKKQVNPFYCNICKIWCASALNLQTHFLGFKHKKVEEALKAHGIVKTASGTGDQVKAPVKLPGYVQTKPERYHGQTLEEQLNTCKDSEPALGLNYIIEYRSKDNFPFLYECQLCHCKTGLSNMFMHVCGSKHRLAYLKQHYPEIAESDEVKGKGSELNRKVRQVALTIEKKEGRKQLKVVIEAPVIRKRWQEYPNADDSPSKAKVQHVDTSLSNEEGIDCKNKDGKLRDPIQEEKSVQEEQENCQKEQAIPDEKVETNKAVEGTKGNLTEESSSSENFEILNEDDAAFILKVTQTLTDALVEYRQQAASKKDLLDNERNGEEALERSTEQSELTSADISDSDTDYSCSRSAKKSLSINEEDELQNFSTGSLDTAYENNITTEFLNSVRNMNVEEVTATLHKIAATNPAFRGMDIPNVVKILTESGTLRRPSNGSTH", "length": 442, "header": "tr|A0A8V0XXG9-1|E1BSP5_CHICK Computationally mapped isoform of U1-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420992 PE=4 SV=1 CANONICAL=E1BSP5-1" }, "locus": { "chromosome": "2", "start_pos": 88736634, "end_pos": 88713735, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019844.1", "url": "https://www.ensembl.org/id/ENSGALT00010019844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011392.1", "url": "https://www.ensembl.org/id/ENSGALP00010011392.1" } ] } }, { "isoform_ac": "A0A8V0XXH4-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP5/entry#A0A8V0XXH4-1", "sequence": { "sequence": "MDPEAEVKKQVNPFYCNICKIWCASALNLQTHFLGFKHKKVEEALKAHGIVQTKPERYHGQTLEEQLNTCKDSEPALGLNYIIEYRSKDNFPFLYECQLCHCKTGLSNMFMHVCGSKHRLAYLKQHYPEIAESDEVKGKGSELNRKVRQVALTIEKKEGRKQLKVVIEAPVIRKRWQEYPNADDSPSKAKVQHVDTSLSNEEGIDCKNKDGKLRDPIQEEKSVQEEQENCQKEQAIPDEKVETNKAVEGTKGNLTEESSSSEKCETNIQLEEENEEVEQTSAAAAEEFTSQEELLSYLQSFEILNEDDAAFILKVTQTLTDALVEYRQQAASKKDLLDNERNGEEALERSTEQSELTSADISDSDTDYSCSRSAKKSLSINEEDELQNFSTGSLDTAYENNITTEFLNSVRNMNVEEVTATLHKIAATNPAFRGMDIPNVVKILTESGTLRRPSNGSTH", "length": 459, "header": "tr|A0A8V0XXH4-1|E1BSP5_CHICK Computationally mapped isoform of U1-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420992 PE=4 SV=1 CANONICAL=E1BSP5-1" }, "locus": { "chromosome": "2", "start_pos": 88736634, "end_pos": 88713735, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019849.1", "url": "https://www.ensembl.org/id/ENSGALT00010019849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011397.1", "url": "https://www.ensembl.org/id/ENSGALP00010011397.1" } ] } }, { "isoform_ac": "A0A8V0XZD4-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP5/entry#A0A8V0XZD4-1", "sequence": { "sequence": "MLPKPVKTASGTGDQVKAPVKLPGYVQTKPERYHGQTLEEQLNTCKDSEPALGLNYIIEYRSKDNFPFLYECQLCHCKTGLSNMFMHVCGSKHRLAYLKQHYPEIAESDEVKGKGSELNRKVRQVALTIEKKEGRKQLKVVIEAPVIRKRWQEYPNADDSPSKAKVQHVDTSLSNEEGIDCKNKDGKLRDPIQEEKSVQEEQENCQKEQAIPDEKVETNKAVEGTKGNLTEESSSSEKCETNIQLEEENEEVEQTSAAAAEEFTSQEELLSYLQSFEILNEDDAAFILKVTQTLTDALVEYRQQAASKKDLLDNERNGEEALERSTEQSELTSADISDSDTDYSCSRSAKKSLSINEEDELQNFSTGSLDTAYENNITTEFLNSVRNMNVEEVTATLHKIAATNPAFRGMDIPNVVKILTESGTLRRPSNGSTH", "length": 434, "header": "tr|A0A8V0XZD4-1|E1BSP5_CHICK Computationally mapped isoform of U1-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420992 PE=4 SV=1 CANONICAL=E1BSP5-1" }, "locus": { "chromosome": "2", "start_pos": 88736634, "end_pos": 88718792, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019842.1", "url": "https://www.ensembl.org/id/ENSGALT00010019842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011390.1", "url": "https://www.ensembl.org/id/ENSGALP00010011390.1" } ] } }, { "isoform_ac": "A0A8V0Y5S1-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP5/entry#A0A8V0Y5S1-1", "sequence": { "sequence": "MDPEAEVKKQVNPFYCNICKIWCASALNLQTHFLGFKHKKVEEALKAHGIVKTASGTGDQVKAPVKLPGYVQTKPERYHGQTLEEQLNTCKDSEPALGLNYIIEYRSKDNFPFLYECQLCHCKTGLSNMFMHVCGSKHRLAYLKQHYPEIAESDEVKGKGSELNRKVRQVALTIEKKEGRKQLKVVIEAPVIRKRWQEYPNADDSPSKAKVQHVDTSLSNEEGIDCKNKDGKLRDPIQEEKSVQEEQENCQKEQAIPDEKVETNKAVEGTKGNLTEESSSSEKCETNIQLEEENEEVEQTSAAAAEEFTSQEELLSYLDLLDNERNGEEALERSTEQSELTSADISDSDTDYSCSRSAKKSLSINEEDELQNFSTGSLDTAYENNITTEFLNSVRNMNVEEVTATLHKIAATNPAFRGMDIPNVVKILTESGTLRRPSNGSTH", "length": 443, "header": "tr|A0A8V0Y5S1-1|E1BSP5_CHICK Computationally mapped isoform of U1-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420992 PE=4 SV=1 CANONICAL=E1BSP5-1" }, "locus": { "chromosome": "2", "start_pos": 88736634, "end_pos": 88713735, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019846.1", "url": "https://www.ensembl.org/id/ENSGALT00010019846.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011394.1", "url": "https://www.ensembl.org/id/ENSGALP00010011394.1" } ] } }, { "isoform_ac": "E1BSP5-1", "url": "https://www.uniprot.org/uniprotkb/E1BSP5/entry#E1BSP5-1", "sequence": { "sequence": "MDPEAEVKKQVNPFYCNICKIWCASALNLQTHFLGFKHKKVEEALKAHGIVKTASGTGDQVKAPVKLPGYVQTKPERYHGQTLEEQLNTCKDSEPALGLNYIIEYRSKDNFPFLYECQLCHCKTGLSNMFMHVCGSKHRLAYLKQHYPEIAESDEVKGKGSELNRKVRQVALTIEKKEGRKQLKVVIEAPVIRKRWQEYPNADDSPSKAKVQHVDTSLSNEEGIDCKNKDGKLRDPIQEEKSVQEEQENCQKEQAIPDEKVETNKAVEGTKGNLTEESSSSEKCETNIQLEEENEEVEQTSAAAAEEFTSQEELLSYLQSFEILNEDDAAFILKVTQTLTDALVEYRQQAASKKDLLDNERNGEEALERSTEQSELTSADISDSDTDYSCSRSAKKSLSINEEDELQNFSTGSLDTAYENNITTEFLNSVRNMNVEEVTATLHKIAATNPAFRGMDIPNVVKILTESGTLRRPSNGSTH", "length": 479, "header": "tr|E1BSP5-1|E1BSP5_CHICK Isoform 1 of U1-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC420992 PE=4 SV=5 CANONICAL=E1BSP5-1" }, "locus": { "chromosome": "2", "start_pos": 88736634, "end_pos": 88713735, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019848.1", "url": "https://www.ensembl.org/id/ENSGALT00010019848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011396.1", "url": "https://www.ensembl.org/id/ENSGALP00010011396.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420992", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420992", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BSP5", "url": "https://www.uniprot.org/uniprotkb/E1BSP5" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "E1BSP5", "url": "https://www.uniprot.org/uniprotkb/E1BSP5" } ], "pmid": "" }, { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "E1BSP5", "url": "https://www.uniprot.org/uniprotkb/E1BSP5" } ], "pmid": "" }, { "name": "single-stranded RNA binding", "id": "GO:0003727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003727", "evidence": [ { "database": "UniProtKB", "id": "E1BSP5", "url": "https://www.uniprot.org/uniprotkb/E1BSP5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSP5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 479, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSP5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSP5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BSP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSP5" }, { "id": "SM00451", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00451" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U1-type", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 45, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 273, "end_pos": 275 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 475, "end_pos": 477 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BWB7-1", "uniprot_ac": "E1BWB7", "uniprot_id": "E1BWB7_CHICK", "mass": { "chemical_mass": 43231.0, "monoisotopic_mass": 43231.0 }, "refseq": { "ac": "XP_419977", "name": "HCLS1-binding protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419977" }, "gene_names": [ { "name": "HS1BP3", "type": "recommended", "evidence": [ { "id": "E1BWB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWB7" } ] }, { "name": "HS1BP3", "type": "synonym", "evidence": [ { "id": "XP_419977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419977" } ] } ], "protein_names": [ { "name": "HCLS1-binding protein 3", "type": "recommended", "evidence": [ { "id": "E1BWB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWB7/entry#names_and_taxonomy" } ] }, { "name": "HCLS1-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419977" } ] }, { "name": "HS1-binding protein 3", "type": "synonym", "evidence": [ { "id": "E1BWB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWB7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_419977.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419977" } ] }, { "annotation": "May be a modulator of IL-2 signaling.", "evidence": [ { "database": "UniProtKB", "id": "E1BWB7", "url": "https://www.uniprot.org/uniprotkb/E1BWB7#function" }, { "database": "UniProtKB", "id": "ARBA00060333", "url": "https://www.uniprot.org/uniprotkb/ARBA00060333#function" }, { "database": "UniProtKB", "id": "A0A8V0XZL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZL8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BWB7", "url": "https://www.uniprot.org/uniprotkb/E1BWB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HS1BP3", "url": "https://www.uniprot.org/uniprotkb/E1BWB7", "locus": { "chromosome": "3", "start_pos": 101698445, "end_pos": 101743569, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007956", "url": "https://www.ensembl.org/id/ENSGALG00010007956" } ] } } ], "crossref": [ { "id": "E1BWB7", "url": "https://alphafold.ebi.ac.uk/entry/E1BWB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016486", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016486", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06868", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06868", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421966", "url": "https://www.ncbi.nlm.nih.gov/gene/421966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NRIQTMN", "url": "https://omabrowser.org/oma/group/NRIQTMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BWB7", "url": "https://www.orthodb.org/?gene=E1BWB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14431:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14431:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419977", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XZL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWB7", "url": "https://www.uniprot.org/uniprotkb/E1BWB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWB7-1", "url": "https://www.uniprot.org/uniprotkb/E1BWB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQHSAAPAVLVTTRQIQNTHTGLDLSVPEYQEVRGKMMSGHVEYHIVVVTRLAAFKSAKHKPEDVVQFMVSKKYSEIEELYQRLSARYPHASLPLLPRKVLFVGESDIYERRAVFNDIMKFISKDEDLATSPELLEFLGTKSTGVIDFKGKNIPDDKEQEDEENDALDFFKEEKTPDLISKLATLENAKKEEKKEEEEEEEDLDPLGIIRTKKTKKASAPPAKEEKHKLIIFEEEVDPNEGLFGPEKDFSSLGPRKKIKENVKLFEDPDLGGMVKLGDSLLLPAACEKREHILNTAPEEDTEELLRVEDDLEKLLKLTSKPKPKVPPKPPLPQKTALFPGNTNSSPLAKPKEDKIQTMNEVDILQYIQENESINDQDTSLF", "length": 381, "header": "tr|E1BWB7-1|E1BWB7_CHICK Isoform 1 of HCLS1-binding protein 3 OS=Gallus gallus OX=9031 GN=HS1BP3 PE=1 SV=1 CANONICAL=E1BWB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XZL8-1", "url": "https://www.uniprot.org/uniprotkb/E1BWB7/entry#A0A8V0XZL8-1", "sequence": { "sequence": "MQHSAAPAVLVTTRQIQNTHTGLDLSVPEYQEVRGKMMSGHVEYHIVVVTRLAAFKSAKHKPEDVVQFMVSKKYSEIEELYQRLSARYPHASLPLLPRKVLFVGESDIYERRAVFNDIMKFISKDEDLATSPELLEFLGTKSTGVIDFKGKNIPDDKEQEDEENDALDFFKEEKTPDLISKLATLENAKKEEKKEEEEEEEDLDPLGIIRTKKTKKASAPPAKEEKHKLIIFEEEVDPNEGLFGPEKDFSSLGPRKKIKENVKLFEDPDLGGMVKLGDSLLLPAACEKREHILNTAPEEDTEELLRLCKSSRLELKNGFRGIKVQAELKPCVNKYETRNVAMLIFPFRAANGGEQRHKGKMTCQRRWRE", "length": 369, "header": "tr|A0A8V0XZL8-1|E1BWB7_CHICK Computationally mapped isoform of HCLS1-binding protein 3 OS=Gallus gallus OX=9031 GN=HS1BP3 PE=1 SV=1 CANONICAL=E1BWB7-1" }, "locus": { "chromosome": "3", "start_pos": 101743376, "end_pos": 101699449, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018970.1", "url": "https://www.ensembl.org/id/ENSGALT00010018970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010519.1", "url": "https://www.ensembl.org/id/ENSGALP00010010519.1" } ] } }, { "isoform_ac": "E1BWB7-1", "url": "https://www.uniprot.org/uniprotkb/E1BWB7/entry#E1BWB7-1", "sequence": { "sequence": "MQHSAAPAVLVTTRQIQNTHTGLDLSVPEYQEVRGKMMSGHVEYHIVVVTRLAAFKSAKHKPEDVVQFMVSKKYSEIEELYQRLSARYPHASLPLLPRKVLFVGESDIYERRAVFNDIMKFISKDEDLATSPELLEFLGTKSTGVIDFKGKNIPDDKEQEDEENDALDFFKEEKTPDLISKLATLENAKKEEKKEEEEEEEDLDPLGIIRTKKTKKASAPPAKEEKHKLIIFEEEVDPNEGLFGPEKDFSSLGPRKKIKENVKLFEDPDLGGMVKLGDSLLLPAACEKREHILNTAPEEDTEELLRVEDDLEKLLKLTSKPKPKVPPKPPLPQKTALFPGNTNSSPLAKPKEDKIQTMNEVDILQYIQENESINDQDTSLF", "length": 381, "header": "tr|E1BWB7-1|E1BWB7_CHICK Isoform 1 of HCLS1-binding protein 3 OS=Gallus gallus OX=9031 GN=HS1BP3 PE=1 SV=1 CANONICAL=E1BWB7-1" }, "locus": { "chromosome": "3", "start_pos": 101743376, "end_pos": 101701298, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018969.1", "url": "https://www.ensembl.org/id/ENSGALT00010018969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010518.1", "url": "https://www.ensembl.org/id/ENSGALP00010010518.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LSP6-1", "protein_name": "HCLS1-binding protein 3", "gene_name": "HS1BP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSPAVLVTSRRVQNVHTGLDLSVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSDIEEFYQKLCSRYPTASLPPLPRKVLFVGEGDIRERRALFDEILRCISKDAELAGSPELLEFLGTRSPGATDLSGRDVSVLDTDSQAGDEDALDFFQQQDRVEDEGLPMLGHQDGDAGKSSEEEEEEALDPLGIMRSKKPKKRPEVAVKPKAVPRLTIFDEEVDPDEGLFGPGRKPSPRSHAENSPPRDPLKLFDDPDLGGAVPLGDPLLLPAAPQSGGATPHEGHREASKELFRVEEDLDQILNLGAEPKPQPKPRPKPKPPVAAKPGLPRKPAMPPRAGPPEAAATQQQKQQQQIQAMDEMDILQYIRDHDAPGQAAPSLF", "length": 395 }, "evidence": [ { "id": "E1BWB7", "url": "https://omabrowser.org/oma/group/E1BWB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8W4F7B2-1", "protein_name": "HCLS1-binding protein 3", "gene_name": "HS1BP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SQHFLCLLSLRRRVQNVHTGLDLTVPQHQEVRGRMMSGHVEYQILAVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLSSRYPAASLPPLPRKVLFVGESDIRERRAVFDEILRCISKDAELAGSPELLEFLGTRSPGAADFSSRDCSVLDTDSQAGDDGDAFDFFQQQDQVESEGLPALGQKGKDAGKSSGEEEEEEEALDPLGIMRSKKPRKHPEVAVKPRPSPRLTIFDEEVDPDEGLFGPGRKPRPEGPTEGGPSRDPLKLFDDPDLGGAVALGDPLLLPAAHESGGPPSRLGPRETSEDLFRVEEDLDQILNLGVEPKPHPQPKPQLKPKPPVAAKPALPRKPAAPPRASPSEAVAGQQRQQQQIQAMDEMDILQYIRDHDAPGQAAPSLF", "length": 400 }, "evidence": [ { "id": "E1BWB7", "url": "https://omabrowser.org/oma/group/E1BWB7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A6D9-1", "protein_name": "HCLS1-binding protein 3", "gene_name": "Hs1bp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQSPAVLVTSRQVQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAVFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLYSRYPEASLPPLPRKVLFVGESDIRERRAMFDEILRCVSKDAQLAGSPELLEFLGTQGTRSPGATGFATRDPSVLDETASRPGDSDEAFDFFEQQDEVQPPTLGLSNKNVEKSLEEEEEEEEILDPLGIMRSKKPKKHQEVAMRTKPSPRLTIFDEEVDPDEGLFSSDKKVSPRRPLGTTEDPLKLFDDPDLGGAVSLGDPLLLPAAHESRGPTSSPEHRDASKELFRVEEDLDQILNLGSEPKPKPQLKPKPLVPSKPALPRKPTVPPAVGPSGTGAGPQKQQQIQAMDEMDILQYIRDQDTLAQDSPSLF", "length": 393 }, "evidence": [ { "id": "E1BWB7", "url": "https://omabrowser.org/oma/group/E1BWB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HDI8-1", "protein_name": "HCLS1-binding protein 3", "gene_name": "Hs1bp3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQSPAVLVTSRQVQNVHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAVFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLSNRYPAASLPPLPRKVLFVGESDIRERRAMFDEILRCVSKDAQLAGSPELLEFLGTRSPGAAGLAARDPFVLDDTASQPGDNDEPFDFFEQQDQVQPPTLGLSNKDVEKSLEEEEEEEEALDPLGIMRSKKPKKRPEVAIRPKPSPRLTIFDEEVDPDAELFGPGKKASPQRPLETTQDSLKLFDDPDLGGAVSLGDPLLLPAARESGGPTSSPEYREASKELFRVEEDLDHILNLGSEPKPKPQPKPKPLVSAKPALPRKPTVPPSVGPSETGAGPQKQQQIQAMDEMDILQYIQDQDTLAQASPSLF", "length": 390 }, "evidence": [ { "id": "E1BWB7", "url": "https://omabrowser.org/oma/group/E1BWB7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TC93-1", "protein_name": "HCLS1-binding protein 3", "gene_name": "Hs1bp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSPAVLRTSRQVQNAHTGLDLSVPQHQEVRGKMMSGHVEYQILVVTRLAVFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLYSCYPAASLPPLPRKVLFVGESDIRERRAMFDEILRCVSKDAQLAGSPELLEFLGTRAPGATGLATRDPSVLDDTASQPGDSDEAFDFFEQQDEVQPPTLGLSSKDVEKSLVGEEEEEEEEEEVLDPLGIMRSKKPKKRPEVAVRPKPAPRLTIFDEEVDPDAGLFSSDKKVSETRRPLETTQDSLKLFDDPDLGGAVSLGDPLLLPAASESRGPTSRPEHGDASKELFRVEEDLDLILNLGSEPKPKPQTKPKPLVPAKPALPRKPTLPASVGPSEPGSGPQKQQQIQAMDEMDILQYIRDHDTLAQDSPSLF", "length": 395 }, "evidence": [ { "id": "E1BWB7", "url": "https://omabrowser.org/oma/group/E1BWB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q53T59-1", "protein_name": "HCLS1-binding protein 3", "gene_name": "HS1BP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQSPAVLVTSRRLQNAHTGLDLTVPQHQEVRGKMMSGHVEYQILVVTRLAAFKSAKHRPEDVVQFLVSKKYSEIEEFYQKLSSRYAAASLPPLPRKVLFVGESDIRERRAVFNEILRCVSKDAELAGSPELLEFLGTRSPGAAGLTSRDSSVLDGTDSQTGNDEEAFDFFEEQDQVAEEGPPVQSLKGEDAEESLEEEEALDPLGIMRSKKPKKHPKVAVKAKPSPRLTIFDEEVDPDEGLFGPGRKLSPQDPSEDVSSVDPLKLFDDPDLGGAIPLGDSLLLPAACESGGPTPSLSHRDASKELFRVEEDLDQILNLGAEPKPKPQLKPKPPVAAKPVIPRKPAVPPKAGPAEAVAGQQKPQEQIQAMDEMDILQYIQDHDTPAQAAPSLF", "length": 392 }, "evidence": [ { "id": "E1BWB7", "url": "https://omabrowser.org/oma/group/E1BWB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "E1BWB7", "url": "https://www.uniprot.org/uniprotkb/E1BWB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BWB7", "url": "https://www.uniprot.org/uniprotkb/E1BWB7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BWB7", "url": "https://www.uniprot.org/uniprotkb/E1BWB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "E1BWB7", "url": "https://www.uniprot.org/uniprotkb/E1BWB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BWB7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 381, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BWB7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BWB7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BWB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWB7" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 145, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 343, "end_pos": 345 }, { "start_pos": 370, "end_pos": 372 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BZQ6-1", "uniprot_ac": "E1BZQ6", "uniprot_id": "E1BZQ6_CHICK", "mass": { "chemical_mass": 89371.0, "monoisotopic_mass": 89371.0 }, "refseq": { "ac": "XP_040512608", "name": "ataxin-7-like protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512608" }, "gene_names": [ { "name": "ATXN7L1", "type": "recommended", "evidence": [ { "id": "E1BZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6" } ] }, { "name": "ATXN7L1", "type": "synonym", "evidence": [ { "id": "XP_040512608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512608" } ] } ], "protein_names": [ { "name": "Ataxin 7 like 1", "type": "synonym", "evidence": [ { "id": "E1BZQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6/entry#names_and_taxonomy" } ] }, { "name": "ataxin-7-like protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_040512608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512608" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040512608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512608" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZQ6", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATXN7L1", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6", "locus": { "chromosome": "1", "start_pos": 14216255, "end_pos": 14325804, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010216", "url": "https://www.ensembl.org/id/ENSGALG00010010216" } ] } } ], "crossref": [ { "id": "E1BZQ6", "url": "https://alphafold.ebi.ac.uk/entry/E1BZQ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008115", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008115", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427847", "url": "https://www.ncbi.nlm.nih.gov/gene/427847", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZU1", "url": "https://www.orthodb.org/?gene=A0A8V0XZU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y616", "url": "https://www.orthodb.org/?gene=A0A8V0Y616", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZQ6", "url": "https://www.orthodb.org/?gene=E1BZQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040512608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040512608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XZU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y616", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y616", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y616-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y616-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZQ6", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALERPVPSPEAFLGQPWAAWVREAAPPHAHGAAPPHSADLEETGKEGAKSREVMRLNKEDMHLFGHYPAHDDFYLVVCNICNQVVKPQVFQSHCERRHGSMCKPSPSPASPACNSRTSLVQMKPKSCISGHNPVSSNSKPFKTPKDNLLTSSSKQHTVFPSKVSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSATTTTITSSSASSSTIPAPTLVKSGLTSKSVPPSPEKILNGKGIIAPSIDKKHQNGTKSSNKPYKRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLNHRRAVPGRKKQFDILLAEHKARSREKEVAKDKEHPPSARESYQSQPTPAQDSLSGSSVNSGQESKVTSPAKSRPPNSVLPRPSSANSINSNSSSNHSGYVPELPLPSMGGDLTSRLSSDEGEVDGAEESEKLDCHFSGHHPRPLGFCSYGSRLMGRGYYVFDRRWDHFRFALNSMVEKHLNSQMWKKIPPAADSPMPSPAAHVSTPFPASVLQPFSNPSAVYIPSTPISSRITSSYIMTSAMLSNAAFVTTSDTNSIMSHTTAFPHVAASLSIMDSTFKAPSAVSPVPAVIPSPSHKPSKTKTSKSSKVKDLSSRSDESSSNKKKKPQSSSSSLSLQTSSSSSFSGSHKKNCVLNTSSTLNSYQATSSYNSMSVHNTNNGTSPLSAKLEPSGRTSLSSSSTDSVKHMSMVVSSIDSSNLSVPSLVHHSGDHSLGAHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKSTANLISAVPDPTSSSISRQIGKNSSVALSQSSPSSTSNPVHNRQKTSNRTGRIRTLP", "length": 834, "header": "tr|E1BZQ6-1|E1BZQ6_CHICK Isoform 1 of Ataxin 7 like 1 OS=Gallus gallus OX=9031 GN=ATXN7L1 PE=4 SV=3 CANONICAL=E1BZQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XZU1-1", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6/entry#A0A8V0XZU1-1", "sequence": { "sequence": "MPSSGAGRVAAPHRGTERLRNLRQSRVQTGCRDFALFHKRRHGSMCKPSPSPASPACNSRTSLVQMKPKSCISGHNPVSSNSKPFKTPKDNLLTSSSKQHTVFPSKVSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSATTTTITSSSASSSTIPAPTLVKSGLTSKSVPPSPEKILNGKGIIAPSIDKKHQNGTKSSNKPYKRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLNHRRAVPGRKKQFDILLAEHKARSREKEVAKDKEHPPSARESYQSQPTPAQDSLSGSSVNSGQESKVTSPAKSRPPNSVLPRPSSANSINSNSSSNHSGYVPELPLPSMGGDLTSRLSSDEGEVDGAEESEKLDCHFSGHHPRPLGFCSYGSRLMGRGYYVFDRRWDHFRFALNSMVEKHLNSQMWKKIPPAADSPMPSPAAHVSTPFPASVLQPFSNPSAVYIPSTPISSRITSSYIMTSAMLSNAAFVTTSDTNSIMSHTTAFPHVAASLSIMDSTFKAPSAVSPVPAVIPSPSHKPSKTKTSKSSKVKDLSSRSDESSSNKKKKPQSSSSSLSLQTSSSSSFSGSHKKNCVLNTSSTLNSYQATSSYNSMSVHNTNNGTSPLSAKLEPSGRTSLSSSSTDSVKHMSMVVSSIDSSNLSVPSLVHHSGDHSLGAHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKSTANLISAVPDPTSSSISRQIGKNSSVALSQSSPSSTSNPVHNRQKTSNRTGRIRTLP", "length": 776, "header": "tr|A0A8V0XZU1-1|E1BZQ6_CHICK Computationally mapped isoform of Ataxin 7 like 1 OS=Gallus gallus OX=9031 GN=ATXN7L1 PE=4 SV=1 CANONICAL=E1BZQ6-1" }, "locus": { "chromosome": "1", "start_pos": 14261418, "end_pos": 14218242, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024313.1", "url": "https://www.ensembl.org/id/ENSGALT00010024313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013825.1", "url": "https://www.ensembl.org/id/ENSGALP00010013825.1" } ] } }, { "isoform_ac": "A0A8V0Y616-1", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6/entry#A0A8V0Y616-1", "sequence": { "sequence": "MRGTMSGVHIMYGRSERRHGSMCKPSPSPASPACNSRTSLVQMKPKSCISGHNPVSSNSKPFKTPKDNLLTSSSKQHTVFPSKVSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSATTTTITSSSASSSTIPAPTLVKSGLTSKSVPPSPEKILNGKGIIAPSIDKKHQNGTKSSNKPYKRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLNHRRAVPGRKKQFDILLAEHKARSREKEVAKDKEHPPSARESYQSQPTPAQDSLSGSSVNSGQESKVTSPAKSRPPNSVLPRPSSANSINSNSSSNHSGYVPELPLPSMGGDLTSRLSSDEGEVDGAEESEKLDCHFSGHHPRPLGFCSYGSRLMGRGYYVFDRRWDHFRFALNSMVEKHLNSQMWKKIPPAADSPMPSPAAHVSTPFPASVLQPFSNPSAVYIPSTPISSRITSSYIMTSAMLSNAAFVTTSDTNSIMSHTTAFPHVAASLSIMDSTFKAPSAVSPVPAVIPSPSHKPSKTKTSKSSKVKDLSSRSDESSSNKKKKPQSSSSSLSLQTSSSSSFSGSHKKNCVLNTSSTLNSYQATSSYNSMSVHNTNNGTSPLSAKLEPSGRTSLSSSSTDSVKHMSMVVSSIDSSNLSVPSLVHHSGDHSLGAHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKSTANLISAVPDPTSSSISRQIGKNSSVALSQSSPSSTSNPVHNRQKTSNRTGRIRTLP", "length": 753, "header": "tr|A0A8V0Y616-1|E1BZQ6_CHICK Computationally mapped isoform of Ataxin 7 like 1 OS=Gallus gallus OX=9031 GN=ATXN7L1 PE=4 SV=1 CANONICAL=E1BZQ6-1" }, "locus": { "chromosome": "1", "start_pos": 14251706, "end_pos": 14218242, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024306.1", "url": "https://www.ensembl.org/id/ENSGALT00010024306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013822.1", "url": "https://www.ensembl.org/id/ENSGALP00010013822.1" } ] } }, { "isoform_ac": "E1BZQ6-1", "url": "https://www.uniprot.org/uniprotkb/E1BZQ6/entry#E1BZQ6-1", "sequence": { "sequence": "MAALERPVPSPEAFLGQPWAAWVREAAPPHAHGAAPPHSADLEETGKEGAKSREVMRLNKEDMHLFGHYPAHDDFYLVVCNICNQVVKPQVFQSHCERRHGSMCKPSPSPASPACNSRTSLVQMKPKSCISGHNPVSSNSKPFKTPKDNLLTSSSKQHTVFPSKVSRDKPCVPVPVVSLEKIPNLVKADGANVKMNSATTTTITSSSASSSTIPAPTLVKSGLTSKSVPPSPEKILNGKGIIAPSIDKKHQNGTKSSNKPYKRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLNHRRAVPGRKKQFDILLAEHKARSREKEVAKDKEHPPSARESYQSQPTPAQDSLSGSSVNSGQESKVTSPAKSRPPNSVLPRPSSANSINSNSSSNHSGYVPELPLPSMGGDLTSRLSSDEGEVDGAEESEKLDCHFSGHHPRPLGFCSYGSRLMGRGYYVFDRRWDHFRFALNSMVEKHLNSQMWKKIPPAADSPMPSPAAHVSTPFPASVLQPFSNPSAVYIPSTPISSRITSSYIMTSAMLSNAAFVTTSDTNSIMSHTTAFPHVAASLSIMDSTFKAPSAVSPVPAVIPSPSHKPSKTKTSKSSKVKDLSSRSDESSSNKKKKPQSSSSSLSLQTSSSSSFSGSHKKNCVLNTSSTLNSYQATSSYNSMSVHNTNNGTSPLSAKLEPSGRTSLSSSSTDSVKHMSMVVSSIDSSNLSVPSLVHHSGDHSLGAHNAVSSLPLSFDKSEGKKRKNSSSSSKACKITKMPGMNSVHRKSTANLISAVPDPTSSSISRQIGKNSSVALSQSSPSSTSNPVHNRQKTSNRTGRIRTLP", "length": 834, "header": "tr|E1BZQ6-1|E1BZQ6_CHICK Isoform 1 of Ataxin 7 like 1 OS=Gallus gallus OX=9031 GN=ATXN7L1 PE=4 SV=3 CANONICAL=E1BZQ6-1" }, "locus": { "chromosome": "1", "start_pos": 14325742, "end_pos": 14218242, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024321.1", "url": "https://www.ensembl.org/id/ENSGALT00010024321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013830.1", "url": "https://www.ensembl.org/id/ENSGALP00010013830.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYY1" } ] }, { "name": "GFOD1", "type": "synonym", "evidence": [ { "id": "XP_001232578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232578" } ] } ], "protein_names": [ { "name": "Gfo/Idh/MocA-like oxidoreductase domain containing 1", "type": "synonym", "evidence": [ { "id": "E1BYY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYY1/entry#names_and_taxonomy" } ] }, { "name": "glucose-fructose oxidoreductase domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001232578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232578" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232578" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYY1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GFOD1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1", "locus": { "chromosome": "2", "start_pos": 61932895, "end_pos": 61868691, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009884", "url": "https://www.ensembl.org/id/ENSGALG00010009884" } ] } } ], "crossref": [ { "id": "E1BYY1", "url": "https://alphafold.ebi.ac.uk/entry/E1BYY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012730", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770283", "url": "https://www.ncbi.nlm.nih.gov/gene/770283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770283", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770283", "database": "KEGG 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF22725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001232578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y3N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYY1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYY1-1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPGVGVFGTGLTARVIVPLLQAEGFAVKALWGRTAEEAEELAKEMSVPFHTSRIDEVLLHQDVDLVCVNLPPPLTRQVAVKTLGIGKNVICDRTATPLDAFRMMTAAHYYPKLMSIMGNVLRFLPAFVKMKQLIQEGYVGELLVCEVQVHSGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTSQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDIIVVGSAGRLIVIGTDLYGQSNSSPQQELLLKDSTPVSNSLLPEKAFSDIPSPYLRGTIKMVQAVRQAFEDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKKSNQLGEWQNISIMTEEPELSPAYLISEAMRKSRMSLYC", "length": 390, "header": "tr|E1BYY1-1|E1BYY1_CHICK Isoform 1 of Gfo/Idh/MocA-like oxidoreductase domain containing 1 OS=Gallus gallus OX=9031 GN=GFOD1 PE=3 SV=1 CANONICAL=E1BYY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y3N4-1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1/entry#A0A8V0Y3N4-1", "sequence": { "sequence": "MSGDLKSWEEKPNQPNQLKCYLSPRTQFFLDGQWELIHQFQKCCFAELRGATCQKAQRSAAHACCIKAGSSTRAVIMGKFTGIGKNVICDRTATPLDAFRMMTAAHYYPKLMSIMGNVLRFLPAFVKMKQLIQEGYVGELLVCEVQVHSGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTSQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDIIVVGSAGRLIVIGTDLYGQSNSSPQQELLLKDSTPVSNSLLPEKAFSDIPSPYLRGTIKMVQAVRQAFEDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKKSNQLGEWQNISIMTEEPELSPAYLISEAMRKSRMSLYC", "length": 387, "header": "tr|A0A8V0Y3N4-1|E1BYY1_CHICK Computationally mapped isoform of Gfo/Idh/MocA-like oxidoreductase domain containing 1 OS=Gallus gallus OX=9031 GN=GFOD1 PE=3 SV=1 CANONICAL=E1BYY1-1" }, "locus": { "chromosome": "2", "start_pos": 61931891, "end_pos": 61895534, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023576.1", "url": "https://www.ensembl.org/id/ENSGALT00010023576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013568.1", "url": "https://www.ensembl.org/id/ENSGALP00010013568.1" } ] } }, { "isoform_ac": "E1BYY1-1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1/entry#E1BYY1-1", "sequence": { "sequence": "MLPGVGVFGTGLTARVIVPLLQAEGFAVKALWGRTAEEAEELAKEMSVPFHTSRIDEVLLHQDVDLVCVNLPPPLTRQVAVKTLGIGKNVICDRTATPLDAFRMMTAAHYYPKLMSIMGNVLRFLPAFVKMKQLIQEGYVGELLVCEVQVHSGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTSQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDIIVVGSAGRLIVIGTDLYGQSNSSPQQELLLKDSTPVSNSLLPEKAFSDIPSPYLRGTIKMVQAVRQAFEDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKKSNQLGEWQNISIMTEEPELSPAYLISEAMRKSRMSLYC", "length": 390, "header": "tr|E1BYY1-1|E1BYY1_CHICK Isoform 1 of Gfo/Idh/MocA-like oxidoreductase domain containing 1 OS=Gallus gallus OX=9031 GN=GFOD1 PE=3 SV=1 CANONICAL=E1BYY1-1" }, "locus": { "chromosome": "2", "start_pos": 61931891, "end_pos": 61868694, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023583.1", "url": "https://www.ensembl.org/id/ENSGALT00010023583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013571.1", "url": "https://www.ensembl.org/id/ENSGALP00010013571.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770283", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770283", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B7W3-1", "protein_name": "Gfo/Idh/MocA-like oxidoreductase domain containing 1", "gene_name": "GFOD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPGVGVFGTSLTARVIIPLLKDEGFSVKALWGRTPEEAEELAKEMSVPFYTSRIDEVLLHQDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMMSAAHYYPKLMSIMGNVLRFLPAFVRMKQLIEEGYVGELLVCEVQVHSGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTGQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDVTVVGSAGRLLAVGTDLYGQRNSAAEQELLVQDATPVSNSLLPEKAFSDIPSPYLRGTIKMMQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQNIAVMTEEPELSPAYLISEAMRRSRVSLYC", "length": 390 }, "evidence": [ { "id": "E1BYY1", "url": "https://omabrowser.org/oma/group/E1BYY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7FCE9-1", "protein_name": "Glucose-fructose oxidoreductase domain-containing protein 1", "gene_name": "gfod1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPGVGVFGTSLTARVIIPLLKGEGFSVKALWGRTQEEAEELARDMNVPFYTNRIDDVLLHPDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMMSAAQYYPKLLSIMGNVLRFLPAFVRMKELLEEGYIGELMVCEAQVHSGSLLGKKYNWSCDDLMGGGGLHSVGSYIIDLLTFLTGRRAAKVHGFLKTFVKQTDHIRGIRQITSDDFCTFQMVLEGGACCTVTLNFNVPGEFRQEVVVVGTAGRLKVCGTDLYGQKNDGECGQELLLKDKTAIGNASLPDKAFRDIPSPYLTGTICMVQAVRQAFQDQDDRRTWDGRPLTMAATFEDCLYALCVVDTIKKSNQCGEWQNIEVMTEEPEVSPAYLISEAMRRSRMSLYC", "length": 391 }, "evidence": [ { "id": "E1BYY1", "url": "https://omabrowser.org/oma/group/E1BYY1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3H0G2-1", "protein_name": "Glucose-fructose oxidoreductase domain-containing protein 1 isoform X1", "gene_name": "Gfod1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPGVGVFGTSLTARVIIPLLKDEGFAVKALWGRTQEEAEELAKEMSVPFYTSRIDEVLLHQDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMMSAAHYYPKLMSIMGNVLRFLPAFVRMKQLIEEGYVGELLVCEVQVHSGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTGQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDVTVVGSAGRLLAVGTDLYGQRNSAPEQELLLQDTTSVSNSLLPEKAFSDIPSPYLRGTMKMMQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQNIAIMTEEPELSPAYLISEAMRRSRMSLYC", "length": 390 }, "evidence": [ { "id": "E1BYY1", "url": "https://omabrowser.org/oma/group/E1BYY1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3UHD2-1", "protein_name": "Glucose-fructose oxidoreductase domain-containing protein 1", "gene_name": "Gfod1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPGVGVFGTSLTARVIIPLLKDEGFAVKALWGRTQEEAEELAKEMSVPFYTSRIDEVLLHQDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMMSAAHYYPKLMSIMGNVLRFLPAFVRMKQLIEEGYVGELLVCEVQVHSGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTGQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDVTVVGSAGRLLAVGTDLYGQRNSAPEQELLLQDTTSVSNSLLPEKAFSDIPSPYLRGTMKMMQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQNIAIMTEEPELSPAYLISEAMRRSRMSLYC", "length": 390 }, "evidence": [ { "id": "E1BYY1", "url": "https://omabrowser.org/oma/group/E1BYY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXC2-1", "protein_name": "Glucose-fructose oxidoreductase domain-containing protein 1", "gene_name": "GFOD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPGVGVFGTSLTARVIIPLLKDEGFAVKALWGRTQEEAEELAKEMSVPFYTSRIDEVLLHQDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMTSAAHYYPKLMSIMGNVLRFLPAFVRMKQLIEEGYVGEPLVCEVQVHGGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTGQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDVTVVGSAGRLLAVGTDLYGQRNSAPEQELLVQDATPVSNSLLPEKAFSDIPSPYLRGTIKMMQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQNIAIMTEEPELSPAYLISEAMRRSRMSLYC", "length": 390 }, "evidence": [ { "id": "E1BYY1", "url": "https://omabrowser.org/oma/group/E1BYY1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y153-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG17712", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLPGVGVFGTGEIANVLVPLLREKGFEVRAIWGRTLKEAKETATTQNVQFHTNVIDDVLLRKDVDLVFIVCQPFLHAEISVKALGIGKHVVCDKPAGLHQQDALKMVRASQYYPTLISLVNHPLRFLPAFTHMRRCLQEELIGSIGDVVLMDVRVQMGTLFPEKYNWMCDAQMGGGALNLVGSVVDLVTFLLQQQAIRVHGVLRSYTKTTPAINGIRQITAPDFCNFQMELASGTLVTVALHSHTVPAKAFSQEVLIYGSKGHLVVRGGDLFVLKEGQPKEEAVYVDVQDLHFATNNSLLPRPYIKGLCKMVGALKEAFGSKESSWVKAPVSTAATFEDGLYVQAVVEAIRKSNETRQWQRVQLSTDSPLNHDQIIRYARMSTM", "length": 384 }, "evidence": [ { "id": "E1BYY1", "url": "https://omabrowser.org/oma/group/E1BYY1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BYY1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "E1BYY1", "url": "https://www.uniprot.org/uniprotkb/E1BYY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BYY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 390, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BYY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BYY1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BYY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYY1" }, { "id": "PF22725", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22725" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GFO/IDH/MocA-like oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 258, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BYY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYY1" }, { "id": "PF01408", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01408" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gfo/Idh/MocA-like oxidoreductase N-terminal", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 110, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 361, "end_pos": 363 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BWM0-1", "uniprot_ac": "E1BWM0", "uniprot_id": "E1BWM0_CHICK", "mass": { "chemical_mass": 33792.0, "monoisotopic_mass": 33792.0 }, "refseq": { "ac": "XP_004944872", "name": "tetratricopeptide repeat protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944872" }, "gene_names": [ { "name": "TTC1", "type": "recommended", "evidence": [ { "id": "E1BWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWM0" } ] }, { "name": "TTC1", "type": "synonym", "evidence": [ { "id": "XP_004944872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944872" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 1", "type": "recommended", "evidence": [ { "id": "E1BWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWM0/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 1", "type": "synonym", "evidence": [ { "id": "XP_004944872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944872" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944872" } ] }, { "annotation": "Adapter protein that plays a role downstream of GNA15 to stimulate Ras activation and subsequent phosphorylation of ERK1/2 independently of phospholipase Cbeta signaling. Mechanistically, interacts with GNA15 and SOS2 to form a macromolecular signaling complex which has a high affinity for HRAS. Additionally, participates in signaling via other G-alpha proteins like GNA14, activating NF-kappa-B through Ras and ERK pathways. Beyond signaling, supports protein homeostasis by cooperating with HSP40 in the HSP70 chaperone cycle, promoting protein folding through the regulated dissociation of the HSP70 inhibitor HSPBP1.", "evidence": [ { "database": "UniProtKB", "id": "E1BWM0", "url": "https://www.uniprot.org/uniprotkb/E1BWM0#function" }, { "database": "UniProtKB", "id": "ARBA00094427", "url": "https://www.uniprot.org/uniprotkb/ARBA00094427#function" }, { "database": "UniProtKB", "id": "A0A8V0Y5B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B1#function" }, { "database": "UniProtKB", "id": "A0A8V0Y9P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BWM0", "url": "https://www.uniprot.org/uniprotkb/E1BWM0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC1", "url": "https://www.uniprot.org/uniprotkb/E1BWM0", "locus": { "chromosome": "13", "start_pos": 7566153, "end_pos": 7601480, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009303", "url": "https://www.ensembl.org/id/ENSGALG00010009303" } ] } } ], "crossref": [ { "id": "E1BWM0", "url": "https://alphafold.ebi.ac.uk/entry/E1BWM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001429", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001429", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416152", "url": "https://www.ncbi.nlm.nih.gov/gene/416152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416152", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416152", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KSAIDDC", "url": "https://omabrowser.org/oma/group/KSAIDDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y5B1", "url": "https://www.orthodb.org/?gene=A0A8V0Y5B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9P6", "url": "https://www.orthodb.org/?gene=A0A8V0Y9P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BWM0", "url": "https://www.orthodb.org/?gene=E1BWM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46014", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46014", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46014:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46014:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y5B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWM0", "url": "https://www.uniprot.org/uniprotkb/E1BWM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWM0-1", "url": "https://www.uniprot.org/uniprotkb/E1BWM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEVKDGHPPEELLDHLKLSDQKSTESTSSWASGPKDAQNLPNLASGDIPSSAKDPTTADECFHDCRDSFEMKEPVLDDEESSQNDENSTRKQTELDEEYLLELEKDMPEEEKQKRRKESTTLKEKGNEQFKKGDYGEAEDSYTKALQICPACFQKDRAVLFSNRAAAKMKQDKTEAALNDCSKAVELDPNYIRALLRRAELHEKTEKLDEALEDYKAILEKDPSVHQAREACMRLPRQIEERNEKLKKEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 296, "header": "tr|E1BWM0-1|E1BWM0_CHICK Isoform 1 of Tetratricopeptide repeat protein 1 OS=Gallus gallus OX=9031 GN=TTC1 PE=1 SV=1 CANONICAL=E1BWM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y5B1-1", "url": "https://www.uniprot.org/uniprotkb/E1BWM0/entry#A0A8V0Y5B1-1", "sequence": { "sequence": "MGPSDMEEVKDGHPPEELLDHLKLSDQKSTESTSSWASGPKDAQNLPNLASGDIPSSAKDPTTADECFHDCRDSFEMKEPVLDDEESSQNDENSTRKQTELDEEYLLELEKDMPEEEKQKRRKESTTLKEKGNEQFKKGDYGEAEDSYTKALQICPACFQKDRAVLFSNRAAAKMKQDKTEAALNDCSKAVELDPNYIRALLRRAELHEKTEKLDEALEDYKAILEKDPSVHQAREACMRLPRQIEERNEKLKKEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 301, "header": "tr|A0A8V0Y5B1-1|E1BWM0_CHICK Computationally mapped isoform of Tetratricopeptide repeat protein 1 OS=Gallus gallus OX=9031 GN=TTC1 PE=1 SV=1 CANONICAL=E1BWM0-1" }, "locus": { "chromosome": "13", "start_pos": 7601115, "end_pos": 7568913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022147.1", "url": "https://www.ensembl.org/id/ENSGALT00010022147.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012705.1", "url": "https://www.ensembl.org/id/ENSGALP00010012705.1" } ] } }, { "isoform_ac": "A0A8V0Y9P6-1", "url": "https://www.uniprot.org/uniprotkb/E1BWM0/entry#A0A8V0Y9P6-1", "sequence": { "sequence": "MLGLPYPEGIMASLGWYHLFLGVSVSTLSIYCQDVCNKLIEGYFSCFYKSNHSKKSDMEEVKDGHPPEELLDHLKLSDQKSTESTSSWASGPKDAQNLPNLASGDIPSSAKDPTTADECFHDCRDSFEMKEPVLDDEESSQNDENSTRKQTELDEEYLLELEKDMPEEEKQKRRKESTTLKEKGNEQFKKGDYGEAEDSYTKALQICPACFQKDRAVLFSNRAAAKMKQDKTEAALNDCSKAVELDPNYIRALLRRAELHEKTEKLDEALEDYKAILEKDPSVHQAREACMRLPRQIEERNEKLKKEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 353, "header": "tr|A0A8V0Y9P6-1|E1BWM0_CHICK Computationally mapped isoform of Tetratricopeptide repeat protein 1 OS=Gallus gallus OX=9031 GN=TTC1 PE=1 SV=1 CANONICAL=E1BWM0-1" }, "locus": { "chromosome": "13", "start_pos": 7601076, "end_pos": 7568913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022145.1", "url": "https://www.ensembl.org/id/ENSGALT00010022145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012703.1", "url": "https://www.ensembl.org/id/ENSGALP00010012703.1" } ] } }, { "isoform_ac": "E1BWM0-1", "url": "https://www.uniprot.org/uniprotkb/E1BWM0/entry#E1BWM0-1", "sequence": { "sequence": "MEEVKDGHPPEELLDHLKLSDQKSTESTSSWASGPKDAQNLPNLASGDIPSSAKDPTTADECFHDCRDSFEMKEPVLDDEESSQNDENSTRKQTELDEEYLLELEKDMPEEEKQKRRKESTTLKEKGNEQFKKGDYGEAEDSYTKALQICPACFQKDRAVLFSNRAAAKMKQDKTEAALNDCSKAVELDPNYIRALLRRAELHEKTEKLDEALEDYKAILEKDPSVHQAREACMRLPRQIEERNEKLKKEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 296, "header": "tr|E1BWM0-1|E1BWM0_CHICK Isoform 1 of Tetratricopeptide repeat protein 1 OS=Gallus gallus OX=9031 GN=TTC1 PE=1 SV=1 CANONICAL=E1BWM0-1" }, "locus": { "chromosome": "13", "start_pos": 7600905, "end_pos": 7568913, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022148.1", "url": "https://www.ensembl.org/id/ENSGALT00010022148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012706.1", "url": "https://www.ensembl.org/id/ENSGALP00010012706.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416152", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416152", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AVJ6-1", "protein_name": "Tetratricopeptide repeat protein 1", "gene_name": "TTC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEKSENCMVSEDMFNGLKVTDTHEAECVSPPVANAKDDHTQSKLHKDVEARPQEDQEEEECFHDSSASFEEEPGPNKVENKSDDDVNSSELDEEYLIELEKNMPDEEKKRRREESSRLKEEGNEQFKKGDYIEAESSYTRALQMCPSCFQKDRSILFSNRAAARMKQDKKEMAISDCSKAIQLNPNYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSVHQAREACMRLPKQIEDRNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 292 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MWJ9-1", "protein_name": "Tetratricopeptide repeat protein 1", "gene_name": "Ttc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGEKSENCKVPEDLFNGLKVTDSQEVESASPQVSDPKVQHSQSKLLKDDGAHSQEDHGEEECFHDCSASFEEEQPGAQMVGDKATDESGSSELDEEYLTELEKNMPEEEKQKRREESTKLKEQGNEQFKRGDYIEAESSYSQALQMCPSCFQKDRSVLFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKLILEKDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNNR", "length": 294 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3ZBR5-1", "protein_name": "Tetratricopeptide repeat protein 1", "gene_name": "TTC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGEKSNCRVPEDLFTGLKVTDPQEAECLHPPVSSGKEQHSQSELLKDVDAQPQEDQGEEECFHDASASFETEEPGADKLENKPEDDMNPSELDEEYLMELEKNMPDEEKKRRREESSRLKEEGNEQFKKGDYIEAESSYTRALQTCPSCFQKDRSVLFSNRAAARMKQEKKEMAISDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSVHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 292 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q66H09-1", "protein_name": "Tetratricopeptide repeat protein 1", "gene_name": "Ttc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGKSEDCKVPEDLFNGLKVTDSQETESASSLVSDPKDQHVQSKPLKDAEAHPQEDHGEEECFHDCSASFEEEQPGAHMAGDKASDESSSELEEEYLIELEKNMPEEEKQKRREESAKLKEEGNEQFKRGDYVEAESSYSQALQMCPACFQKDRSVLFSNRAAARMKQDKKEMAITDCSKAIQLNPTYIRAILRRAELYEKTDKLDEALEDYKSILETDPSVHQAREACVRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 292 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91Z38-1", "protein_name": "Tetratricopeptide repeat protein 1", "gene_name": "Ttc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEKSEDCKVPEDLFNGLKVADPQEGESASPMVSDPKGQHCQSKLPKAAEAHPQDDHVEEECFHDCSASFEEEQPGAHVAGSKASDDSSSELDEEYLIELEKNMPEEEKQKRREESAKLKEEGNERFKRGDYMEAESSYSQALQMCPACFQKDRSVLFSNRAAARMKQDKKETAITDCSKAIQLNPTYIRAILRRAELYEKTDKLDEALEDYKSVLEKDPSVHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 292 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99614-1", "protein_name": "Tetratricopeptide repeat protein 1", "gene_name": "TTC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEKSENCGVPEDLLNGLKVTDTQEAECAGPPVPDPKNQHSQSKLLRDDEAHLQEDQGEEECFHDCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR", "length": 292 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M0B2-1", "protein_name": "Tetratricopeptide repeat (TPR)-like superfamily protein", "gene_name": "TPR1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLIESSESEDEILIKNEPKPASSSSPQPTETKQVDGDDSDGFETASEREISDEEGEEDGTKNDAVTSQEEPQHSEKKEEQIELMSEGEAIVDDGSNKEKALAEANEAKAEGNKLFVNGLYEEALSKYAFALELVQELPESIELRSICYLNRGVCFLKLGKCEETIKECTKALELNPTYNKALVRRAEAHEKLEHFEDAVTDLKKILELDPSNDQARKGIRRLEPLAAEKREKMKEEAITKLKEMGNSILGRFGMSVDNFKAVKDPNTGSYSLSFQN", "length": 277 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VEV3-1", "protein_name": "Tetratricopeptide repeat protein 1", "gene_name": "Ttc1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGNANSDDEFHDAIGEEITEKEATSTRQSEKDVDEIVEKQNQLALDDEAEQGAAGGDSIATPTTVDSELTIEELREREKDLSPEQLTANKEKADKLKVEGNELFKNDDAEGAAKTYTEALDICPSASSKERAVLYGNRAAAKIKLEANKAAIDDCTKAIELWPEYVRVLLRRAKLYEQEDKPDEALEDYKKVTEIDPGQQEAREAQIRLPPIINERNEKLKNEMMSSLKDLGNMILKPFGLSTQNFQMQQDPNTGSYSINFK", "length": 263 }, "evidence": [ { "id": "E1BWM0", "url": "https://omabrowser.org/oma/group/E1BWM0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BWM0", "url": "https://www.uniprot.org/uniprotkb/E1BWM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BWM0", "url": "https://www.uniprot.org/uniprotkb/E1BWM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of neuroinflammatory response", "id": "GO:0150078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150078", "evidence": [ { "database": "UniProtKB", "id": "E1BWM0", "url": "https://www.uniprot.org/uniprotkb/E1BWM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BWY4-1", "uniprot_ac": "E1BWY4", "uniprot_id": "E1BWY4_CHICK", "mass": { "chemical_mass": 51292.0, "monoisotopic_mass": 51292.0 }, "refseq": { "ac": "XP_003643005", "name": "WD repeat-containing protein 41", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643005" }, "gene_names": [ { "name": "WDR41", "type": "recommended", "evidence": [ { "id": "E1BWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ] }, { "name": "WDR41", "type": "synonym", "evidence": [ { "id": "XP_003643005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643005" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 41", "type": "recommended", "evidence": [ { "id": "E1BWY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWY4/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 41", "type": "synonym", "evidence": [ { "id": "XP_003643005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643005" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643005" } ] }, { "annotation": "Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. As part of the C9orf72-SMCR8 complex, stimulates RAB8A and RAB11A GTPase activity in vitro, however WDR42 is shown not be an essential complex component for this function. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ULK1/ATG1 kinase complex and inhibiting its protein kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PI07", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI07#function" }, { "database": "UniProtKB", "id": "ARBA00055081", "url": "https://www.uniprot.org/uniprotkb/ARBA00055081#function" }, { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4#function" }, { "database": "UniProtKB", "id": "A0A8V0YD31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD31#function" }, { "database": "UniProtKB", "id": "A0A8V0Y8F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8F3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR41", "url": "https://www.uniprot.org/uniprotkb/E1BWY4", "locus": { "chromosome": "Z", "start_pos": 23790496, "end_pos": 23724380, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010254", "url": "https://www.ensembl.org/id/ENSGALG00010010254" } ] } } ], "crossref": [ { "id": "E1BWY4", "url": "https://alphafold.ebi.ac.uk/entry/E1BWY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004350", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004350", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416366", "url": "https://www.ncbi.nlm.nih.gov/gene/416366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416366", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCLWNAQ", "url": "https://omabrowser.org/oma/group/VCLWNAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PI07", "url": "https://www.orthodb.org/?gene=A0A1D5PI07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y662", "url": "https://www.orthodb.org/?gene=A0A8V0Y662", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8F3", "url": "https://www.orthodb.org/?gene=A0A8V0Y8F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD31", "url": "https://www.orthodb.org/?gene=A0A8V0YD31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BWY4", "url": "https://www.orthodb.org/?gene=E1BWY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22805:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22805:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PI07", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PI07-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y662", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y662", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y662-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y662-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8F3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BWY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRWLIGGGREPQGLAEKSSVQTIGEEQVQNPYTELLVLKGHQDIVRFLVQIDDYRFASAGDDGIIFLWNAQTGEKLFELHGHTHKITAIAPFFSSDASEENSHLILTASADRAVIVWDCTTGRQVQKVSCFHSTVKCLTVLQRLDVWLSGGSDLCVWNRKLDLLCKTSHLTDAGISALVELPKNCVAAAVGKELIIFRLIASSDKSEGWNILEVKRLVDHQDNILSLVSVNDLTFATGSHVGELIVWDALDWTKQASECNFWDSSVQPDTRTEIKLSQSPNETSVQHLASDEENVYAAVGKGIYVYNLQMKRVIACQRTAHDSSVLHIEMLPNRQLISCSEDGSVRIWEIREKQQLPTEPVPTGFFNMWGFGRANKQANQAKKVQENTPMHFLELVGDLIGHSSAVQMFLYFSELGLVTCSADHLVILWKDGERESRLRSLTLFQKLAQNGDLQLKF", "length": 458, "header": "tr|E1BWY4-1|E1BWY4_CHICK Isoform 1 of WD repeat-containing protein 41 OS=Gallus gallus OX=9031 GN=WDR41 PE=4 SV=2 CANONICAL=E1BWY4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PI07-1", "url": "https://www.uniprot.org/uniprotkb/E1BWY4/entry#A0A1D5PI07-1", "sequence": { "sequence": "GSHSSSAAKSSVQTIGEEQVQNPYTELLVLKGHQDIVRFLVQIDDYRFASAGDDGIIFLWNAQTGEKLFELHGHTHKITAIAPFFSSDASEENSHLILTASADRAVIVWDCTTGRQVQKVSCFHSTVKCLTVLQRLDVWLSGGSDLCVWNRKLDLLCKTSHLTDAGISALVELPKNCVAAAVGKELIIFRLIASSDKSEGWNILEVKRLVDHQDNILSLVSVNDLTFATGSHVGELIVWDALDWTKQASECNFWDSSVQPDTRTEIKLSQSPNETSVQHLASDEENVYAAVGKGIYVYNLQMKRVIACQRTAHDSSVLHIEMLPNRQLISCSEDGSVRIWEIREKQQLPTEPVPTGFFNMWGFGRANKQANQAKKVQENTPMHFLELVGDLIGHSSAVQMFLYFSELGLVTCSADHLVILWKDGERESRLRSLTLFQKLAQNGDLQLKF", "length": 449, "header": "tr|A0A1D5PI07-1|A0A1D5PI07_CHICK Computationally mapped isoform of WD repeat-containing protein 41 OS=Gallus gallus OX=9031 GN=WDR41 PE=4 SV=2 CANONICAL=E1BWY4-1" }, "locus": { "chromosome": "Z", "start_pos": 23744937, "end_pos": 23724898, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024427.1", "url": "https://www.ensembl.org/id/ENSGALT00010024427.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013866.1", "url": "https://www.ensembl.org/id/ENSGALP00010013866.1" } ] } }, { "isoform_ac": "A0A8V0Y662-1", "url": "https://www.uniprot.org/uniprotkb/E1BWY4/entry#A0A8V0Y662-1", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKSSVQTIGEEQVQNPYTELLVLKGHQDIVRFLVQIDDYRFASAGDDGIIFLWNAQTGEKLFELHGHTHKITAIAPFFSSDASEENSHLILTASADRAVIVWDCTTGRQVQKVSCFHSTVKCLTVLQRLDVWLSGGSDLCVWNRKLDLLCKTSHLTDAGISALVELPKNCVAAAVGKELIIFRLIASSDKSEGWNILEVKRLVDHQDNILSLVSVNDLTFATGSHVGELIVWDALDWTKQASECNFWDSSVQPDTRTEIKLSQSPNETSVQHLASDEENVYAAVGKGIYVYNLQMKRVIACQRTAHDSSVLHIEMLPNRQLISCSEDGSVRIWEIREKQQLPTEPVPTGFFNMWGFGRANKQANQAKKVQENTPMHFLELVGDLIGHSSAVQDLLNQYKAGGDNLLDCIITGDEMWCHHYKT", "length": 438, "header": "tr|A0A8V0Y662-1|E1BWY4_CHICK Computationally mapped isoform of WD repeat-containing protein 41 OS=Gallus gallus OX=9031 GN=WDR41 PE=4 SV=1 CANONICAL=E1BWY4-1" }, "locus": { "chromosome": "Z", "start_pos": 23790495, "end_pos": 23724467, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024448.1", "url": "https://www.ensembl.org/id/ENSGALT00010024448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013878.1", "url": "https://www.ensembl.org/id/ENSGALP00010013878.1" } ] } }, { "isoform_ac": "A0A8V0Y8F3-1", "url": "https://www.uniprot.org/uniprotkb/E1BWY4/entry#A0A8V0Y8F3-1", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKSSVQTIGEEQVQNPYTELLVLKGHQDIVRFLVQIDDYRFASAGDDGIIFLWNAQTGEKLFELHGHTHKITAIAPFFSSDASEENSHLILTASADRAVIVWDCTTGRQVQKVSCFHSTVKCLTVLQRLDVWLSGGSDLCVWNRKLDLLCKTSHLTDAGISALVELPKNCVAAAVGKELIIFRLIASSDKSEGWNILEVKRLVDHQDNILSLVSVNDLTFATGSHVGELIVWDALDWTKQASECNFWDSSVQPDTRTEIKLSQSPNETSVQHLASDEENVYAAVGKGIYVYNLQMKRVIACQRTAHDSSVLHIEMLPNRQLISCSEDGSVRIWEIREKQQLPTEPVPTGFFNMWGFGRANKQANQAKKVQENTPMHFLELVGDLIGHSSAVQMFLYFSELGLVTCSADHLVILWKDGERESRLRSLTLFQKLAQNDLSKAEFCMFLWK", "length": 464, "header": "tr|A0A8V0Y8F3-1|E1BWY4_CHICK Computationally mapped isoform of WD repeat-containing protein 41 OS=Gallus gallus OX=9031 GN=WDR41 PE=4 SV=1 CANONICAL=E1BWY4-1" }, "locus": { "chromosome": "Z", "start_pos": 23748483, "end_pos": 23724467, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024441.1", "url": "https://www.ensembl.org/id/ENSGALT00010024441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013874.1", "url": "https://www.ensembl.org/id/ENSGALP00010013874.1" } ] } }, { "isoform_ac": "A0A8V0YD31-1", "url": "https://www.uniprot.org/uniprotkb/E1BWY4/entry#A0A8V0YD31-1", "sequence": { "sequence": "TEFITHFKTSFLCCSFDHSLLLQEADKVIEDGDHDWKRIRFASAGDDGIIFLWNAQTGEKLFELHGHTHKITAIAPFFSSDASEENSHLILTASADRAVIVWDCTTGRQVQKVSCFHSTVKCLTVLQRLDVWLSGGSDLCVWNRKLDLLCKTSHLTDAGISALVELPKNCVAAAVGKELIIFRLIASSDKSEGWNILEVKRLVDHQDNILSLVSVNDLTFATGSHVGELIVWDALDWTKQASECNFWDSSVQPDTRTEIKLSQSPNETSVQHLASDEENVYAAVGKGIYVYNLQMKRVIACQRTAHDSSVLHIEMLPNRQLISCSEDGSVRIWEIREKQQLPTEPVPTGFFNMWGFGRANKQANQAKKVQENTPMHFLELVGDLIGHSSAVQMFLYFSELGLVTCSADHLVILWKDGERESRLRSLTLFQKLAQNGDLQLKF", "length": 442, "header": "tr|A0A8V0YD31-1|E1BWY4_CHICK Computationally mapped isoform of WD repeat-containing protein 41 OS=Gallus gallus OX=9031 GN=WDR41 PE=4 SV=1 CANONICAL=E1BWY4-1" }, "locus": { "chromosome": "Z", "start_pos": 23744937, "end_pos": 23730237, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024422.1", "url": "https://www.ensembl.org/id/ENSGALT00010024422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013862.1", "url": "https://www.ensembl.org/id/ENSGALP00010013862.1" } ] } }, { "isoform_ac": "E1BWY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BWY4/entry#E1BWY4-1", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKSSVQTIGEEQVQNPYTELLVLKGHQDIVRFLVQIDDYRFASAGDDGIIFLWNAQTGEKLFELHGHTHKITAIAPFFSSDASEENSHLILTASADRAVIVWDCTTGRQVQKVSCFHSTVKCLTVLQRLDVWLSGGSDLCVWNRKLDLLCKTSHLTDAGISALVELPKNCVAAAVGKELIIFRLIASSDKSEGWNILEVKRLVDHQDNILSLVSVNDLTFATGSHVGELIVWDALDWTKQASECNFWDSSVQPDTRTEIKLSQSPNETSVQHLASDEENVYAAVGKGIYVYNLQMKRVIACQRTAHDSSVLHIEMLPNRQLISCSEDGSVRIWEIREKQQLPTEPVPTGFFNMWGFGRANKQANQAKKVQENTPMHFLELVGDLIGHSSAVQMFLYFSELGLVTCSADHLVILWKDGERESRLRSLTLFQKLAQNGDLQLKF", "length": 458, "header": "tr|E1BWY4-1|E1BWY4_CHICK Isoform 1 of WD repeat-containing protein 41 OS=Gallus gallus OX=9031 GN=WDR41 PE=4 SV=2 CANONICAL=E1BWY4-1" }, "locus": { "chromosome": "Z", "start_pos": 23744937, "end_pos": 23724467, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024432.1", "url": "https://www.ensembl.org/id/ENSGALT00010024432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013869.1", "url": "https://www.ensembl.org/id/ENSGALP00010013869.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416366", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416366", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1Q4U0-1", "protein_name": "WD repeat-containing protein 41", "gene_name": "wdr41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRWILGGREAQGAVEKSAALFIGEEQPKNCFTEMQVLKGHFDIVRFLVQIDDLRFASAGDDGLVLIWNVETGDCLLELRGHTQQITAMTSYTFIRGGNTHTALITASSDRTLSLWDPDSGNRVQNISDLQSSVKCLLVLNLLDMWLSGGNELCVWNQDFELQCKTVHHSDTGISAMVELPKNFIAAAMDKEIVIFKLNVSGSDVAVMAIRHLADHQDTIHSLISINDGLFASGSHIGELIIWDSVDWTIQGYELILWEESKGDGHSEVKVTQQKQIERSIQHMSSDGELLVAAVGSGLYVYNVLTKTVVAYRKMAHDSNVLHTMIQTDGLMSCSEDGSVRMWELQDLPLPAEPASSGFFGMFGTFGRSSKHAGPPAKKLPEVPDLRSLELIGDLIGHSGAVQMFVSFEQKALVTCSTDHLLIVWKDGELQSQLRSLAVFQKLEENQQL", "length": 449 }, "evidence": [ { "id": "E1BWY4", "url": "https://omabrowser.org/oma/group/E1BWY4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UDP0-1", "protein_name": "WD repeat-containing protein 41", "gene_name": "Wdr41", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKAALQTIGEDQGQNPYTELLVLEAHRDIVRFLVRLDDFRFASAGDDGIIVVWNAQTGEKLLELRGHTQKITAVIAFPPLDSCEASSQLLLTASADRTVGVWDCDTGRQIQRVTCFQSTVKCLTVLQRLDIWLSGGSDLGVWNRKLDLLCKTSHLSDTGISALVEIPGNCVAAAVGRELIIFRLVTPTEELPEWDIIEVKRLLDHQDNILSLANINDTGFVTGSHVGELLIWDALDWTVQACERTFWSPTAQLDAQQEIKLFQKQNDISINHFTCDEENIFAAVGRGLYVYNLQLKRVIACQKTAHDSNILHIDKLPNRQLISCSEDGAVRMWEVREKQQLAAEPVPTGFFNMWGFGRVNKQASQPVKKQEENVTTCSLELIGDLIGHSSSVEMFLYFEDHGLVTCSADHLIILWKNGERESGVRSLKLFQKLEENGDLYPESP", "length": 460 }, "evidence": [ { "id": "E1BWY4", "url": "https://omabrowser.org/oma/group/E1BWY4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HAD4-1", "protein_name": "WD repeat-containing protein 41", "gene_name": "WDR41", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKSPLQTIGEEQTQNPYTELLVLKAHHDIVRFLVQLDDYRFASAGDDGIVVVWNAQTGEKLLELNGHTQKITAIITFPSLESCEEKNQLILTASADRTVIVWDGDTTRQVQRISCFQSTVKCLTVLQRLDVWLSGGNDLCVWNRKLDLLCKTSHLSDTGISALVEIPKNCVVAAVGKELIIFRLVAPTEGSLEWDILEVKRLLDHQDNILSLINVNDLSFVTGSHVGELIIWDALDWTMQAYERNFWDPSPQLDTQQEIKLCQKSNDISIHHFTCDEENVFAAVGRGLYVYSLQMKRVIACQKTAHDSNVLHVARLPNRQLISCSEDGSVRIWELREKQQLAAEPVPTGFFNMWGFGRVSKQASQPVKKQQENATSCSLELIGDLIGHSSSVEMFLYFEDHGLVTCSADHLIILWKNGERESGLRSLRLFQKLEENGDLYLAV", "length": 459 }, "evidence": [ { "id": "E1BWY4", "url": "https://omabrowser.org/oma/group/E1BWY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor complex", "id": "GO:0032045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032045", "evidence": [ { "database": "UniProtKB", "id": "E1BWY4", "url": "https://www.uniprot.org/uniprotkb/E1BWY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BVM7-1", "uniprot_ac": "E1BVM7", "uniprot_id": "E1BVM7_CHICK", "mass": { "chemical_mass": 26550.0, "monoisotopic_mass": 26550.0 }, "refseq": { "ac": "XP_003640423", "name": "coiled-coil domain-containing protein 134 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640423" }, "gene_names": [ { "name": "CCDC134", "type": "recommended", "evidence": [ { "id": "E1BVM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ] }, { "name": "CCDC134", "type": "synonym", "evidence": [ { "id": "XP_003640423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640423" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 134", "type": "synonym", "evidence": [ { "id": "E1BVM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM7/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 134 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_003640423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC134", "url": "https://www.uniprot.org/uniprotkb/E1BVM7", "locus": { "chromosome": "1", "start_pos": 49550537, "end_pos": 49555453, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010740", "url": "https://www.ensembl.org/id/ENSGALG00010010740" } ] } } ], "crossref": [ { "id": "E1BVM7", "url": "https://alphafold.ebi.ac.uk/entry/E1BVM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011918", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011918", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417984", "url": "https://www.ncbi.nlm.nih.gov/gene/417984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417984", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417984", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIGFCNQ", "url": "https://omabrowser.org/oma/group/GIGFCNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y670", "url": "https://www.orthodb.org/?gene=A0A8V0Y670", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA16", "url": "https://www.orthodb.org/?gene=A0A8V0YA16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YEP3", "url": "https://www.orthodb.org/?gene=A0A8V0YEP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVM7", "url": "https://www.orthodb.org/?gene=E1BVM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14735:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14735:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y670", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y670", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y670-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y670-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YEP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YEP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BVM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFLWICLILLAVVLPEGSLADLEKQRMGSGLEIYKKLFEVKRKDQMNALKNLIELNDINQQYKIIDIMLKGLFKVLEDSRAVLIAADVPPDGPFPQDEKLKDAYSHVVENTAFFGDVVLRFPKIVHHYFDRNSNWNNLIRWGIGFCNLTGVFEQGPHSQLLGLMAQELGISEKSPNYRNPFKADHSEFFPSADTFQKALREEEKRRRKEEKRKEIRKGPRISRSQSEL", "length": 229, "header": "tr|E1BVM7-1|E1BVM7_CHICK Isoform 1 of Coiled-coil domain containing 134 OS=Gallus gallus OX=9031 GN=CCDC134 PE=1 SV=2 CANONICAL=E1BVM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y670-1", "url": "https://www.uniprot.org/uniprotkb/E1BVM7/entry#A0A8V0Y670-1", "sequence": { "sequence": "MIQLGDPSTAVCEQGMAAVASTMDFLWICLILLAVVLPEGSLADLEKQRMGSGLEIYKKLFEVKRKDQMNALKNLIELNDINQQYKIIDIMLKGLFKVLEDSRAVLIAADVPPDGPFPQDEKLKDAYSHVVENTAFFGDVVLRFPKIVHHYFDRNSNWNNLIRWGIGFCNLTGVFEQGPHSQLLGLMAQELGISEKSPNYRNPFKADHSEFFPSADTFQKALREEEKRRRKEEKRKEIRKGPRISRSQSEL", "length": 251, "header": "tr|A0A8V0Y670-1|E1BVM7_CHICK Computationally mapped isoform of Coiled-coil domain containing 134 OS=Gallus gallus OX=9031 GN=CCDC134 PE=1 SV=1 CANONICAL=E1BVM7-1" }, "locus": { "chromosome": "1", "start_pos": 49553470, "end_pos": 49550809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025643.1", "url": "https://www.ensembl.org/id/ENSGALT00010025643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014451.1", "url": "https://www.ensembl.org/id/ENSGALP00010014451.1" } ] } }, { "isoform_ac": "A0A8V0YA16-1", "url": "https://www.uniprot.org/uniprotkb/E1BVM7/entry#A0A8V0YA16-1", "sequence": { "sequence": "MGDGEADGTWSVTLMIQLGDPSTAVCEQGMAAVASTMDFLWICLILLAVVLPEGSLADLEKQRMGSGLEIYKKLFEVKRKDQMNALKNLIELNDINQQYKIIDIMLKGLFKVLEDSRAVLIAADVPPDGPFPQDEKLKDAYSHVVENTAFFGDVVLRFPKIVHHYFDRNSNWNNLIRWGIGFCNLTGVFEQGPHSQLLGLMAQELGISEKSPNYRNPFKADHSEFFPSADTFQKALREEEKRRRKEEKRKEIRKGPRISRSQSEL", "length": 265, "header": "tr|A0A8V0YA16-1|E1BVM7_CHICK Computationally mapped isoform of Coiled-coil domain containing 134 OS=Gallus gallus OX=9031 GN=CCDC134 PE=1 SV=1 CANONICAL=E1BVM7-1" }, "locus": { "chromosome": "1", "start_pos": 49554029, "end_pos": 49550809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025640.1", "url": "https://www.ensembl.org/id/ENSGALT00010025640.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014450.1", "url": "https://www.ensembl.org/id/ENSGALP00010014450.1" } ] } }, { "isoform_ac": "A0A8V0YEP3-1", "url": "https://www.uniprot.org/uniprotkb/E1BVM7/entry#A0A8V0YEP3-1", "sequence": { "sequence": "MRLSHAVASTMDFLWICLILLAVVLPEGSLADLEKQRMGSGLEIYKKLFEVKRKDQMNALKNLIELNDINQQYKIIDIMLKGLFKVLEDSRAVLIAADVPPDGPFPQDEKLKDAYSHVVENTAFFGDVVLRFPKIVHHYFDRNSNWNNLIRWGIGFCNLTGVFEQGPHSQLLGLMAQELGISEKSPNYRNPFKADHSEFFPSADTFQKALREEEKRRRKEEKRKEIRKGPRISRSQSEL", "length": 239, "header": "tr|A0A8V0YEP3-1|E1BVM7_CHICK Computationally mapped isoform of Coiled-coil domain containing 134 OS=Gallus gallus OX=9031 GN=CCDC134 PE=1 SV=1 CANONICAL=E1BVM7-1" }, "locus": { "chromosome": "1", "start_pos": 49554287, "end_pos": 49550809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025645.1", "url": "https://www.ensembl.org/id/ENSGALT00010025645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014453.1", "url": "https://www.ensembl.org/id/ENSGALP00010014453.1" } ] } }, { "isoform_ac": "E1BVM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BVM7/entry#E1BVM7-1", "sequence": { "sequence": "MDFLWICLILLAVVLPEGSLADLEKQRMGSGLEIYKKLFEVKRKDQMNALKNLIELNDINQQYKIIDIMLKGLFKVLEDSRAVLIAADVPPDGPFPQDEKLKDAYSHVVENTAFFGDVVLRFPKIVHHYFDRNSNWNNLIRWGIGFCNLTGVFEQGPHSQLLGLMAQELGISEKSPNYRNPFKADHSEFFPSADTFQKALREEEKRRRKEEKRKEIRKGPRISRSQSEL", "length": 229, "header": "tr|E1BVM7-1|E1BVM7_CHICK Isoform 1 of Coiled-coil domain containing 134 OS=Gallus gallus OX=9031 GN=CCDC134 PE=1 SV=2 CANONICAL=E1BVM7-1" }, "locus": { "chromosome": "1", "start_pos": 49553262, "end_pos": 49550809, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025646.1", "url": "https://www.ensembl.org/id/ENSGALT00010025646.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014454.1", "url": "https://www.ensembl.org/id/ENSGALP00010014454.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417984", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417984", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KTT4-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "ccdc134", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSVCALLLLAAPAALGSDSDRHRHDSNLEIYKRLFETKRKDQLNALKNLVELNDVNQQYKIIDIMLKGLFKVLEDSRAVLIAANMRPDDPFPLDDKLKEAYSHVVENTAFFGDVALRFPRIVHHYYERNADWSVLLRWGLSFCNHTGVFSGGAHQHVLTLMSQELGITEKSADFVNPYRTERDDVLQTAEAFQKILREEEKRRRKEEKRKEIRKGPRISRSRNEL", "length": 226 }, "evidence": [ { "id": "E1BVM7", "url": "https://omabrowser.org/oma/group/E1BVM7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287A6Q1-1", "protein_name": "Coiled-coil domain containing 134", "gene_name": "CCDC134", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLLQFPAFLSVLLLSGTAVTGTLSTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDVHQQYKILDVMLKGLFKVLEDSRTVLIAANVLPEGPFPQDEKLKDAFSQVVENTAFFGDVVLRFPRIVHHYFDHNSNWNLLIRWGISFCNQSGVFDQGPHSPILSLMAQELGISEKDSDFQNPFKVDRTEFISSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BVM7", "url": "https://omabrowser.org/oma/group/E1BVM7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MJE0-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "Ccdc134", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLLQFLVSFFVLLLSGSEVTGTQKTTLDPSLKIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLTAANVLPDGPLPQDEKLKDAFSHVVENTAFFGDVVLRFPKIVHHYFDHNSNWNLLIRWGISFCNQTGVFDQGPHSPILNLMAQELGISEKDSDFQNPFKIDRTEFIPSTDPFQKALREEEKRRKKEERRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BVM7", "url": "https://omabrowser.org/oma/group/E1BVM7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BFW1-1", "protein_name": "Coiled-coil domain containing 134", "gene_name": "CCDC134", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLLQFLTSLSVLLLSGTGVTDTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDVHQQYKILDVMLKGLFKVLEDSRTVLTAAGVLPDGPFPQDEKLKDAFSQVVENTAFFGDVVLRFPRIVHHYFDHNSNWNLLIRWGISFCNQSGVFDQGPHSPILGLMAQELGISEKHSDFQNPFKVDRTEFISSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BVM7", "url": "https://omabrowser.org/oma/group/E1BVM7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M862-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "Ccdc134", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLQSLAVFFVLLLPGTEVTGTLKSTLDPSLKIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLIAADVLPDGPLPQDEKLKDAFSHVVENTAFFGDVVLRFPKIVHHYFDHNSNWNLLIRWGISFCNQTGVFDQGPHSPVLSLMAQELGITEKDSDFQNPFTIDRTEFIPSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BVM7", "url": "https://omabrowser.org/oma/group/E1BVM7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C7V8-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "Ccdc134", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLLQFLAAFSVLLWPGTEVTGALKSTLDPSLKIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLIAADVLPDGPVPQDEKLKDAFSHVVENTAFFGDVVLRFPKIVHHYFDHNSNWNLLIRWGISFCNQTGVFDQGPHSPILSLMAQELGITEKDSDFRNPFKTDQTEFIPSTDPFQKALREEEKRRKKEERRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BVM7", "url": "https://omabrowser.org/oma/group/E1BVM7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6E4-1", "protein_name": "Coiled-coil domain-containing protein 134", "gene_name": "CCDC134", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLLQFLAFLFVLLLSGMGATGTLRTSLDPSLEIYKKMFEVKRREQLLALKNLAQLNDIHQQYKILDVMLKGLFKVLEDSRTVLTAADVLPDGPFPQDEKLKDAFSHVVENTAFFGDVVLRFPRIVHYYFDHNSNWNLLIRWGISFCNQTGVFNQGPHSPILSLMAQELGISEKDSNFQNPFKIDRTEFIPSTDPFQKALREEEKRRKKEEKRKEIRKGPRISRSQSEL", "length": 229 }, "evidence": [ { "id": "E1BVM7", "url": "https://omabrowser.org/oma/group/E1BVM7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of ossification", "id": "GO:0030278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030278", "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "pmid": "" }, { "name": "regulation of glycoprotein biosynthetic process", "id": "GO:0010559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010559", "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "pmid": "" }, { "name": "positive regulation of Wnt signaling pathway", "id": "GO:0030177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177", "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "pmid": "" }, { "name": "positive regulation of MyD88-dependent toll-like receptor signaling pathway", "id": "GO:0034126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034126", "evidence": [ { "database": "UniProtKB", "id": "E1BVM7", "url": "https://www.uniprot.org/uniprotkb/E1BVM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQR7-1", "uniprot_ac": "E1BQR7", "uniprot_id": "E1BQR7_CHICK", "mass": { "chemical_mass": 128350.0, "monoisotopic_mass": 128350.0 }, "refseq": { "ac": "XP_015142263", "name": "ELKS/Rab6-interacting/CAST family member 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142263" }, "gene_names": [ { "name": "ERC1", "type": "recommended", "evidence": [ { "id": "E1BQR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ] }, { "name": "ERC1", "type": "synonym", "evidence": [ { "id": "XP_015142263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142263" } ] } ], "protein_names": [ { "name": "ELKS/RAB6-interacting/CAST family member 1", "type": "synonym", "evidence": [ { "id": "E1BQR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQR7/entry#names_and_taxonomy" } ] }, { "name": "ELKS/Rab6-interacting/CAST family member 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_015142263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142263" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142263" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERC1", "url": "https://www.uniprot.org/uniprotkb/E1BQR7", "locus": { "chromosome": "1", "start_pos": 60890943, "end_pos": 60605738, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012399", "url": "https://www.ensembl.org/id/ENSGALG00010012399" } ] } } ], "crossref": [ { "id": "E1BQR7", "url": "https://alphafold.ebi.ac.uk/entry/E1BQR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012994", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012994", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418153", "url": "https://www.ncbi.nlm.nih.gov/gene/418153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PT87", "url": "https://www.orthodb.org/?gene=A0A1D5PT87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y993", "url": "https://www.orthodb.org/?gene=A0A8V0Y993", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFI9", "url": "https://www.orthodb.org/?gene=A0A8V0YFI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQR7", "url": "https://www.orthodb.org/?gene=E1BQR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18861:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18861:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015142263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PT87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PT87-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y993", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y993", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y993-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y993-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGSARSVGKAEPSNQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSTGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGADTPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSAKEVQGEDLKKRVAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTALCHDRDPLILRGLTPPASYHLDDDRAAWEKELQKMTQEQLRDELEKGEKESAELQEFANAILQQIADHCPDILEQVVNALEESS", "length": 1117, "header": "tr|E1BQR7-1|E1BQR7_CHICK Isoform 1 of ELKS/RAB6-interacting/CAST family member 1 OS=Gallus gallus OX=9031 GN=ERC1 PE=1 SV=2 CANONICAL=E1BQR7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PT87-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR7/entry#A0A1D5PT87-1", "sequence": { "sequence": "MYGSARSVGKAEPSNQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSTGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGADTPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSAKEVQGEDLKKRVAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTALCHDRDPLILRGLTPPASYHLDDDRAAWEKELQKMTQEQLRDELEKGEKESAELQEFANAILQQIADHCPDILEQVVNALEESS", "length": 1073, "header": "tr|A0A1D5PT87-1|A0A1D5PT87_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 1 OS=Gallus gallus OX=9031 GN=ERC1 PE=1 SV=2 CANONICAL=E1BQR7-1" }, "locus": { "chromosome": "1", "start_pos": 60890814, "end_pos": 60616299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029701.1", "url": "https://www.ensembl.org/id/ENSGALT00010029701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017285.1", "url": "https://www.ensembl.org/id/ENSGALP00010017285.1" } ] } }, { "isoform_ac": "A0A8V0Y993-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR7/entry#A0A8V0Y993-1", "sequence": { "sequence": "MYGSARSVGKAEPSNQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSTGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGADTPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSAKEVQGEDLKKRVAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQDEEEGIWA", "length": 1017, "header": "tr|A0A8V0Y993-1|E1BQR7_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 1 OS=Gallus gallus OX=9031 GN=ERC1 PE=1 SV=1 CANONICAL=E1BQR7-1" }, "locus": { "chromosome": "1", "start_pos": 60864371, "end_pos": 60616299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029698.1", "url": "https://www.ensembl.org/id/ENSGALT00010029698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017282.1", "url": "https://www.ensembl.org/id/ENSGALP00010017282.1" } ] } }, { "isoform_ac": "A0A8V0YFI9-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR7/entry#A0A8V0YFI9-1", "sequence": { "sequence": "MYGSARSVGKAEPSNQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSTGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGADTPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTALCHDRDPLILRGLTPPASYHLDDDRAAWEKELQKMTQEQLRDELEKGEKESAELQEFANAILQQIADHCPDILEQVVNALEESS", "length": 1093, "header": "tr|A0A8V0YFI9-1|A0A8V0YFI9_CHICK Computationally mapped isoform of ELKS/RAB6-interacting/CAST family member 1 OS=Gallus gallus OX=9031 GN=ERC1 PE=1 SV=1 CANONICAL=E1BQR7-1" }, "locus": { "chromosome": "1", "start_pos": 60890814, "end_pos": 60616299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029700.1", "url": "https://www.ensembl.org/id/ENSGALT00010029700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017284.1", "url": "https://www.ensembl.org/id/ENSGALP00010017284.1" } ] } }, { "isoform_ac": "E1BQR7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR7/entry#E1BQR7-1", "sequence": { "sequence": "MYGSARSVGKAEPSNQSPGRSPRLPRSPRLGHRRTNSTGGSSGSSTGGGSGKTLSMENIQSLNAAYATSGPMYLSDHENVGADTPKSTMTLGRSGGRLPYGVRMTAMGSSPNIASSGVASDTIAFGEHHLPPVSMASTVPHSLRQARDNTIMDLQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKEQYRVLQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTSEPFVAELTEENFQRLHTEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENNMLREEIHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSAKEVQGEDLKKRVAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQEIAEEKGTQAGEIHDLKDMLEVKERKVNVLQKKIENLQEQLRDKEKQMSSLKDRVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDTYKKDIKDLKEKVGILQGDLTEKESSLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMETQLKKAHEATLEARASPELSDRMQQLEREVTRYREESSKAQAEVDRLLEILKEMENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDNLRKKDDRIEELEEALRESVQITAEREMVLAQEESARINAEKQVEELMMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQDEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHLKSSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTALCHDRDPLILRGLTPPASYHLDDDRAAWEKELQKMTQEQLRDELEKGEKESAELQEFANAILQQIADHCPDILEQVVNALEESS", "length": 1117, "header": "tr|E1BQR7-1|E1BQR7_CHICK Isoform 1 of ELKS/RAB6-interacting/CAST family member 1 OS=Gallus gallus OX=9031 GN=ERC1 PE=1 SV=2 CANONICAL=E1BQR7-1" }, "locus": { "chromosome": "1", "start_pos": 60890814, "end_pos": 60616299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029699.1", "url": "https://www.ensembl.org/id/ENSGALT00010029699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017283.1", "url": "https://www.ensembl.org/id/ENSGALP00010017283.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" }, { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" }, { "name": "IkappaB kinase complex", "id": "GO:0008385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008385", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of presynaptic active zone", "id": "GO:0098882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098882", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "maintenance of presynaptic active zone structure", "id": "GO:0048790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048790", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "E1BQR7", "url": "https://www.uniprot.org/uniprotkb/E1BQR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1020, "end_pos": 1022, "annotation": "n_glycosylation_sequon" }, { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQR7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1117, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQR7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQR7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1020, "end_pos": 1022 }, { "start_pos": 15, "end_pos": 17 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 822, "end_pos": 824 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM04-1", "uniprot_ac": "A0A8V1AM04", "uniprot_id": "A0A8V1AM04_CHICK", "mass": { "chemical_mass": 103630.0, "monoisotopic_mass": 103630.0 }, "refseq": {}, "gene_names": [ { "name": "FAM129B", "type": "recommended", "evidence": [ { "id": "A0A8V1AM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ] } ], "protein_names": [ { "name": "Niban apoptosis regulator 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM129B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04", "locus": {} } ], "crossref": [ { "id": "A0A8V1AM04", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM04", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23949", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23949", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFY9", "url": "https://www.orthodb.org/?gene=A0A8V1AFY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI10", "url": "https://www.orthodb.org/?gene=A0A8V1AI10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK85", "url": "https://www.orthodb.org/?gene=A0A8V1AK85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM04", "url": "https://www.orthodb.org/?gene=A0A8V1AM04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14392", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14392", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14392:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14392:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFDIQMHIPSVRRSCTQSLGSSRRQAATHPGGSQATGPCFACCFALSPVDFVSSSRAALQKTGKVLGEFSRCYREQYGVALFNSIRYEIEGNGGPQAQLLHRKVPLEDHVIYSGNLFQYIEENKKWRNRFCVVPHNYGLVLYENKLAYERELPPRVLINSAGYKVLTSVEQYLELVSSSLPGITPKSGNTPILKCPTDFPLILWHPYARHYYFCLMTGKEQEKWGAVFQDCVRHCNNGISEDSKVEAPAFTDAVRMYRQSKEQYGTWDMLCGNQSQVLSNLVMEELLPELRSAIGPRLKGKTQERQRTWIQISDAVYRMVYEQTKAQYDAMVAKCELERPQMESSIRTDMDQIITSKEHLASKIRAFVLPKAEICVRNHVQPYISSILEALMTPTSQGFAEVREVFFKEVTDMNMNIVNEGGLEKLVEYMEKLSHLAFHPVKMQSCYEKMEQLKLEGLQQRFDVSSTSVFKQRAQIHMRQQMDDALYTFETLLHQELGKLQGKDELCKSIQRILERVLKKYDYDSSTVRKKFFREALLQITIPFLLKKLAPTCKGELAKFQELIFEDFASFILVENTYEEVVLQSVMKDIMQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLGEGSPIDWGEEHGGQPEAEPAADKRRRAKQVVSVIQDDEGALPYEMGAEMLMSPSSPEPPEPRVPPGSPDGVAEIREALAKESIEVLTEERLTNGTHSTQDSGATKEVVVAAGAAPGDGPNKGPASDGGGARRAAPAAPTSGAKVPSEDGVRHAPAAPPAPEAESAARDEVQRAVPASPTTGSEVLSQDGLHRAAPASSVSGAEVTSGAEIPSGDKVPHGTSASPAPGADVPPSDKVHRGVPASPAPRAEIPPGDEVHHATPASPAPRAEVPLPPAGTTCHQRSDKETGEEVALPEACSPPQPAGTTESIEGMQTEF", "length": 940, "header": "tr|A0A8V1AM04-1|A0A8V1AM04_CHICK Isoform 1 of Niban apoptosis regulator 2 OS=Gallus gallus OX=9031 GN=FAM129B PE=1 SV=1 CANONICAL=A0A8V1AM04-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04/entry#A0A8V1AFY9-1", "sequence": { "sequence": "MCSPLTWTRAAGSTSQVPLEDHVIYSGNLFQYIEENKKWRNRFCVVPHNYGLVLYENKLAYERELPPRVLINSAGYKVLTSVEQYLELVSSSLPGITPKSGNTPILKCPTDFPLILWHPYARHYYFCLMTGKEQEKWGAVFQDCVRHCNNGISEDSKVEAPAFTDAVRMYRQSKEQYGTWDMLCGNQSQVLSNLVMEELLPELRSAIGPRLKGKTQERQRTWIQISDAVYRMVYEQTKAQYDAMVAKCELERPQMESSIRTDMDQIITSKEHLASKIRAFVLPKAEICVRNHVQPYISSILEALMTPTSQGFAEVREVFFKEVTDMNMNIVNEGGLEKLVEYMEKLSHLAFHPVKMQSCYEKMEQLKLEGLQQRFDVSSTSVFKQRAQIHMRQQMDDALYTFETLLHQELGKLQGKDELCKSIQRILERVLKKYDYDSSTVRKKFFREALLQITIPFLLKKLAPTCKGELAKFQELIFEDFASFILVENTYEEVVLQSVMKDIMQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLGEGSPIDWGEEHGGQPEAEPAADKRRRAKQVVSVIQDDEGALPYEMGAEMLMSPSSPEPPEPRVPPGSPDGVAEIREALAKESIEVLTEERLTNGTHSTQDSGATKEVVVAAGAAPGDGPNKGPASDGGGARRAAPAAPTSGAKVPSEDGVRHAPAAPPAPEAESAARDEVQRAVPASPTTGSEVLSQDGLHRAAPASSVSGAEVTSGAEIPSGDKVPHGTSASPAPGADVPPSDKVHRGVPASPAPRAEIPPGDEVHHATPASPAPRAEVPLPPAGTTCHQRSDKETGEEVALPEACSPPQPAGTTESIEGMQTEF", "length": 852, "header": "tr|A0A8V1AFY9-1|A0A8V1AM04_CHICK Computationally mapped isoform of Niban apoptosis regulator 2 OS=Gallus gallus OX=9031 GN=FAM129B PE=1 SV=1 CANONICAL=A0A8V1AM04-1" }, "locus": { "chromosome": "17", "start_pos": 3104965, "end_pos": 3086904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069895.1", "url": "https://www.ensembl.org/id/ENSGALT00010069895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043021.1", "url": "https://www.ensembl.org/id/ENSGALP00010043021.1" } ] } }, { "isoform_ac": "A0A8V1AI10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04/entry#A0A8V1AI10-1", "sequence": { "sequence": "MGDVLSSHLDEGRRQHIAEKTGKVLGEFSRCYREQYGVALFNSIRYEIEGNGGPQAQLLHRKVPLEDHVIYSGNLFQYIEENKKWRNRFCVVPHNYGLVLYENKLAYERELPPRVLINSAGYKVLTSVEQYLELVSSSLPGITPKSGNTPILKCPTDFPLILWHPYARHYYFCLMTGKEQEKWGAVFQDCVRHCNNGISEDSKVEAPAFTDAVRMYRQSKEQYGTWDMLCGNQSQVLSNLVMEELLPELRSAIGPRLKGKTQERQRTWIQISDAVYRMVYEQTKAQYDAMVAKCELERPQMESSIRTDMDQIITSKEHLASKIRAFVLPKAEICVRNHVQPYISSILEALMTPTSQGFAEVREVFFKEVTDMNMNIVNEGGLEKLVEYMEKLSHLAFHPVKMQSCYEKMEQLKLEGLQQRFDVSSTSVFKQRAQIHMRQQMDDALYTFETLLHQELGKLQGKDELCKSIQRILERVLKKYDYDSSTVRKKFFREALLQITIPFLLKKLAPTCKGELAKFQELIFEDFASFILVENTYEEVVLQSVMKDIMQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLGEGSPIDWGEEHGGQPEAEPAADKRRRAKQVVSVIQDDEGALPYEMGAEMLMSPSSPEPPEPRVPPGSPDGVAEIREALAKESIEVLTEERLTNGTHSTQDSGATKEVVVAAGAAPGDGPNKGPASDGGGARRAAPAAPTSGAKVPSEDGVRHAPAAPPAPEAESAARDEVQRAVPASPTTGSEVLSQDGLHRAAPASSVSGAEVTSGAEIPSGDKVPHGTSASPAPGADVPLPPAGTTCHQRSDKETGEEVALPEACSPPQPAGTTESIEGMQTEF", "length": 858, "header": "tr|A0A8V1AI10-1|A0A8V1AM04_CHICK Computationally mapped isoform of Niban apoptosis regulator 2 OS=Gallus gallus OX=9031 GN=FAM129B PE=1 SV=1 CANONICAL=A0A8V1AM04-1" }, "locus": { "chromosome": "17", "start_pos": 3104972, "end_pos": 3086904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069897.1", "url": "https://www.ensembl.org/id/ENSGALT00010069897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043023.1", "url": "https://www.ensembl.org/id/ENSGALP00010043023.1" } ] } }, { "isoform_ac": "A0A8V1AK85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04/entry#A0A8V1AK85-1", "sequence": { "sequence": "MGDVLSSHLDEGRRQHIAEKTGKVLGEFSRCYREQYGVALFNSIRYEIEGNGGPQAQLLHRKVPLEDHVIYSGNLFQYIEENKKWRNRFCVVPHNYGLVLYENKLAYERELPPRVLINSAGYKVLTSVEQYLELVSSSLPGISEDSKVEAPAFTDAVRMYRQSKEQYGTWDMLCGNQSQVLSNLVMEELLPELRSAIGPRLKGKTQERQRTWIQISDAVYRMVYEQTKAQYDAMVAKCELERPQMESSIRTDMDQIITSKEHLASKIRAFVLPKAEICVRNHVQPYISSILEALMTPTSQGFAEVREVFFKEVTDMNMNIVNEGGLEKLVEYMEKLSHLAFHPVKMQSCYEKMEQLKLEGLQQRFDVSSTSVFKQRAQIHMRQQMDDALYTFETLLHQELGKLQGKDELCKSIQRILERVLKKYDYDSSTVRKKFFREALLQITIPFLLKKLAPTCKGELAKFQELIFEDFASFILVENTYEEVVLQSVMKDIMQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLGEGSPIDWGEEHGGQPEAEPAADKRRRAKQVVSVIQDDEGALPYEMGAEMLMSPSSPEPPEPRVPPGSPDGVAEIREALAKESIEVLTEERLTNGTHSTQDSGATKEVVVAAGAAPGDGPNKGPASDGGGARRAAPAAPTSGAKVPSEDGVRHAPAAPPAPEAESAARDEVQRAVPASPTTGSEVLSQDGLHRAAPASSVSGAEVTSGAEIPSGDKVPHGTSASPAPGADVPPSDKVHRGVPASPAPRAEIPPGDEVHHATPASPAPRAEVPLPPAGTTCHQRSDKETGEEVALPEACSPPQPAGTTESIEGMQTEF", "length": 842, "header": "tr|A0A8V1AK85-1|A0A8V1AM04_CHICK Computationally mapped isoform of Niban apoptosis regulator 2 OS=Gallus gallus OX=9031 GN=FAM129B PE=1 SV=1 CANONICAL=A0A8V1AM04-1" }, "locus": { "chromosome": "17", "start_pos": 3104972, "end_pos": 3086904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069896.1", "url": "https://www.ensembl.org/id/ENSGALT00010069896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043022.1", "url": "https://www.ensembl.org/id/ENSGALP00010043022.1" } ] } }, { "isoform_ac": "A0A8V1AM04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04/entry#A0A8V1AM04-1", "sequence": { "sequence": "MLFDIQMHIPSVRRSCTQSLGSSRRQAATHPGGSQATGPCFACCFALSPVDFVSSSRAALQKTGKVLGEFSRCYREQYGVALFNSIRYEIEGNGGPQAQLLHRKVPLEDHVIYSGNLFQYIEENKKWRNRFCVVPHNYGLVLYENKLAYERELPPRVLINSAGYKVLTSVEQYLELVSSSLPGITPKSGNTPILKCPTDFPLILWHPYARHYYFCLMTGKEQEKWGAVFQDCVRHCNNGISEDSKVEAPAFTDAVRMYRQSKEQYGTWDMLCGNQSQVLSNLVMEELLPELRSAIGPRLKGKTQERQRTWIQISDAVYRMVYEQTKAQYDAMVAKCELERPQMESSIRTDMDQIITSKEHLASKIRAFVLPKAEICVRNHVQPYISSILEALMTPTSQGFAEVREVFFKEVTDMNMNIVNEGGLEKLVEYMEKLSHLAFHPVKMQSCYEKMEQLKLEGLQQRFDVSSTSVFKQRAQIHMRQQMDDALYTFETLLHQELGKLQGKDELCKSIQRILERVLKKYDYDSSTVRKKFFREALLQITIPFLLKKLAPTCKGELAKFQELIFEDFASFILVENTYEEVVLQSVMKDIMQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLGEGSPIDWGEEHGGQPEAEPAADKRRRAKQVVSVIQDDEGALPYEMGAEMLMSPSSPEPPEPRVPPGSPDGVAEIREALAKESIEVLTEERLTNGTHSTQDSGATKEVVVAAGAAPGDGPNKGPASDGGGARRAAPAAPTSGAKVPSEDGVRHAPAAPPAPEAESAARDEVQRAVPASPTTGSEVLSQDGLHRAAPASSVSGAEVTSGAEIPSGDKVPHGTSASPAPGADVPPSDKVHRGVPASPAPRAEIPPGDEVHHATPASPAPRAEVPLPPAGTTCHQRSDKETGEEVALPEACSPPQPAGTTESIEGMQTEF", "length": 940, "header": "tr|A0A8V1AM04-1|A0A8V1AM04_CHICK Isoform 1 of Niban apoptosis regulator 2 OS=Gallus gallus OX=9031 GN=FAM129B PE=1 SV=1 CANONICAL=A0A8V1AM04-1" }, "locus": { "chromosome": "17", "start_pos": 3101243, "end_pos": 3086904, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069894.1", "url": "https://www.ensembl.org/id/ENSGALT00010069894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043020.1", "url": "https://www.ensembl.org/id/ENSGALP00010043020.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 763, "start_aa": "Thr", "end_pos": 763, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr763", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "gonadotropin secretion", "id": "GO:0032274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" }, { "name": "negative regulation of DNA biosynthetic process", "id": "GO:2000279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 717, "end_pos": 719, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AM04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM04" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 234, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 763 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 717, "end_pos": 719 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM31-1", "uniprot_ac": "A0A8V1AM31", "uniprot_id": "A0A8V1AM31_CHICK", "mass": { "chemical_mass": 145350.0, "monoisotopic_mass": 145350.0 }, "refseq": { "ac": "XP_003642322", "name": "astrotactin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642322" }, "gene_names": [ { "name": "ASTN2", "type": "recommended", "evidence": [ { "id": "A0A8V1AM31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ] }, { "name": "ASTN2", "type": "synonym", "evidence": [ { "id": "XP_003642322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642322" } ] } ], "protein_names": [ { "name": "Astrotactin-2", "type": "recommended", "evidence": [ { "id": "A0A8V1AM31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31/entry#names_and_taxonomy" } ] }, { "name": "astrotactin-2", "type": "synonym", "evidence": [ { "id": "XP_003642322", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642322" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642322.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642322" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASTN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31", "locus": { "chromosome": "17", "start_pos": 3899583, "end_pos": 4161858, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028903", "url": "https://www.ensembl.org/id/ENSGALG00010028903" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417242", "url": "https://www.ncbi.nlm.nih.gov/gene/417242", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417242", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417242", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VXCPEEL", "url": "https://omabrowser.org/oma/group/VXCPEEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAQ3", "url": "https://www.orthodb.org/?gene=A0A8V1AAQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG19", "url": "https://www.orthodb.org/?gene=A0A8V1AG19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI47", "url": "https://www.orthodb.org/?gene=A0A8V1AI47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKB4", "url": "https://www.orthodb.org/?gene=A0A8V1AKB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM31", "url": "https://www.orthodb.org/?gene=A0A8V1AM31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16592:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16592:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18411", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18411", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642322", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642322", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG19", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPPRRRSASPAPLPPVPPALLVLAVLLGGGPGAAAVAAAAASREPPGPCRVKTVTVSTLPVLRENDISWSGAPPPAAADSRLLLFVRSELPGRVAVQDDLDNTELPFFTLEMSGTVADISLVHWKQQWLENGTLYFHVSMSSAEQLSRATPPSLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWHKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRNSRLQAHNSVIGVPIRETPILDDYEDEEEEETPQRAEPSTREDEFGSQVTRTLESLGRGGEEKPDYEKKAPEVTQETVESLMQKFKESFRTNTPIEIGQLQPALRSTSVGRRKRRSRPRGGIGFGRAKGNSGSEADDETQLTFYTEQYRSRRRSKGSMKSPVNKTALTLIAVSSCILAMVCGSQLSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDQETGECSCHEGYAPDPMHRHLCVRTDWGHSEGPWPYTTLERGYDLVTGEQAPEKILRSTYSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSTGCVCPEDLRPMKDGTGCYDYSKGIDCSDGFNGGCEQLCLQQTLPLPHDPSSSTIFMFCGCVEEYKLAPDGKSCLMLSDICEGPKCLKSDAKFNDTLFGEMLHGYNNRSQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIKYDEAMGYPMVQHWRVRSNLYRVKLSSITLSSGFANILKILNKDSSREELLSFIQQFGSHYIAEALYGSEFSCTIHFPSKKVQQQLWLQYQKETTELGNKKELKSMPFITYLSGLLTAQMLSDDHLISGVEIHCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYALIQDNDTRQAFKGALMSSYWCSGKGDVIEDWCRCDLNAFDENGLPNCSPLPQPVLRLSPSVEPSSTVVSLEWLDVQPAIGTKVSDYVLHHKKVDEYTDTDLYTGESLSFADDLLSGLATSCVAAGRSHGDVPETSLYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDSKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLEKVSSHCSTLLRSAYIQSRTETMPYLFCRSEEVRPPGMVWYSILKDTKVTCEEKMVSMLRNTYGESKGR", "length": 1303, "header": "tr|A0A8V1AM31-1|A0A8V1AM31_CHICK Isoform 1 of Astrotactin-2 OS=Gallus gallus OX=9031 GN=ASTN2 PE=3 SV=1 CANONICAL=A0A8V1AM31-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31/entry#A0A8V1AAQ3-1", "sequence": { "sequence": "MSGTVADISLVHWKQQWLENGTLYFHVSMSSAEQLSRATPPSLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWHKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRNSRLQAHNSVIGVPIRETPILDDYEDEEEEETPQRAEPSTREDEFGSQVTRTLESLGRGGEEKPDYEKKAPEVTQETVESLMQKFKESFRTNTPIEIGQLQPALRSTSVGRRKRRSRPRGGIGFGRAKGNSGSEADDETQLTFYTEQYRSRRRSKGSMKSPVNKTALTLIAVSSCILAMVCGSQLSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDQETGECSCHEGYAPDPMHRHLCVRTDWGHSEGPWPYTTLERGYDLVTGEQAPEKILRSTYSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSTGCVCPEDLRPMKDGTGCYDYSKGIDCSDGFNGGCEQLCLQQTLPLPHDPSSSTIFMFCGCVEEYKLAPDGKSCLMLSDICEGPKCLKSDAKFNDTLFGEMLHGYNNRSQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIKYDEAMGYPMVQHWRVRSNLYRVKLSSITLSSGFANILKILNKDSSREELLSFIQQFGSHYIAEALYGSEFSCTIHFPSKKVQQQLWLQYQKETTELGNKKELKSMPFITYLSGLLTAQMLSDDHLISGVEIHCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYALIQDNDTRQAFKGALMSSYWCSGKGDVIEDWCRCDLNAFDENGLPNCSPLPQPVLRLSPSVEPSSTVVSLEWLDVQPAIGTKVSDYVLHHKKVDEYTDTDLYTGESLSFADDLLSGLATSCVAAGRSHGDVPETSLYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDSKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLEKVSSHCSTLLRSAYIQSRTETMPYLFCRSEEVRPPGMVWYSILKDTKVTCEEKMVSMLRNTYGESKGR", "length": 1190, "header": "tr|A0A8V1AAQ3-1|A0A8V1AAQ3_CHICK Computationally mapped isoform of Astrotactin-2 OS=Gallus gallus OX=9031 GN=ASTN2 PE=3 SV=1 CANONICAL=A0A8V1AM31-1" }, "locus": { "chromosome": "17", "start_pos": 4123409, "end_pos": 3900512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069933.1", "url": "https://www.ensembl.org/id/ENSGALT00010069933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043059.1", "url": "https://www.ensembl.org/id/ENSGALP00010043059.1" } ] } }, { "isoform_ac": "A0A8V1AG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31/entry#A0A8V1AG19-1", "sequence": { "sequence": "MAAPPRRRSASPAPLPPVPPALLVLAVLLGGGPGAAAVAAAAASREPPGPCRVKTVTVSTLPVLRENDISWSGAPPPAAADSRLLLFVRSELPGRVAVQDDLDNTELPFFTLEMSGTVADISLVHWKQQWLENGTLYFHVSMSSAEQLSRATPPSLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWHKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRNSRLQAHNSVIGVPIRETPILDDYEDEEEEETPQRAEPSTREDEFGSQVTRTLESLGRGGEEKPDYEKKGWWPLCLVFPSACALRSLMQKFKESFRTNTPIEIGQLQPALRSTSVGRRKRRSRPRGGIGFGRAKGNSGSEADDETQLTFYTEQYRSRRRSKGSMKSPVNKTALTLIAVSSCILAMVCGSQLSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDQETGECSCHEGYAPDPMHRHLCVRTDWGHSEGPWPYTTLERGYDLVTGEQAPEKILRSTYSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSTGCVCPEDLRPMKDGTGCYDYSKGIDCSDGFNGGCEQLCLQQTLPLPHDPSSSTIFMFCGCVEEYKLAPDGKSCLMLSDICEGPKCLKSDAKFNDTLFGEMLHGYNNRSQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGTNIKYDEAMGYPMVQHWRVRSNLYRVKLSFANILKILNKDSSREELLSFIQQFGSHYIAEALYGSEFSCTIHFPSKKVQQQLWLQYQKGEEETTELGNKKELKSMPFITYLSGLLTAQMLSDDHLISGVEIHCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYALIQDNDTRQVSALMSSYWCSGKGDVIEDWCRCDLNAFDENGLPNCSPLPQPVLRLSPSVEPSSTVVSLEWLDVQPAIGTKVSDYVLHHKKVDETTFFISHEVSSHNNPVVSDQEMKTFFFHFLPFRFTLYAVDTRGRHSELSTVTLRTACPLVDDSKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLEKVSSHCSTLLRSAYIQSRTETMPYLFCRSEEVRPPGMVWYSILKDTKVTCEEKMVSMLRNTYGESKGR", "length": 1281, "header": "tr|A0A8V1AG19-1|A0A8V1AM31_CHICK Computationally mapped isoform of Astrotactin-2 OS=Gallus gallus OX=9031 GN=ASTN2 PE=3 SV=1 CANONICAL=A0A8V1AM31-1" }, "locus": { "chromosome": "17", "start_pos": 4161436, "end_pos": 3900512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069930.1", "url": "https://www.ensembl.org/id/ENSGALT00010069930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043056.1", "url": "https://www.ensembl.org/id/ENSGALP00010043056.1" } ] } }, { "isoform_ac": "A0A8V1AI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31/entry#A0A8V1AI47-1", "sequence": { "sequence": "MSGTVADISLVHWKQQWLENGTLYFHVSMSSAEQLSRATPPSLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWHKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRNSRLQAHNSVIGVPIRETPILDDYEDEEEEETPQRAEPSTREDEFGSQVTRTLESLGRGGEEKPDYEKKAPEVTQETVESLMQKFKESFRTNTPIEIGQLQPALRSTSVGRRKRRSRPRGGIGFGRAKGNSGSEADDETQLTFYTEQYRSRRRSKGSMKSPVNKTALTLIAVSSCILAMVCGSQLSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDQETGECSCHEGYAPDPMHRHLCVRTDWGHSEGPWPYTTLERGYDLVTGEQAPEKILRSTYSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSTGCVCPEDLRPMKDGTGCYDYSKGIDCSDGFNGGCEQLCLQQTLPLPHDPSSSTIFMFCGCVEEYKLAPDGKSCLMLSDICEGPKCLKSDAKFNDTLFGEMLHGYNNRSQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIKYDEAMGYPMVQHWRVRSNLYRVKLSSITLSSGFANILKILNKDSSREELLSFIQQFGSHYIAEALYGSEFSCTIHFPSKKVQQQLWLQYQKETTELGNKKELKSMPFITYLSGLLTAQMLSDDHLISGVEIHCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYALIQDNDTRQAFKGALMSSYWCSGKGDVIEDWCRCDLNAFDENGLPNCSPLPQPVLRLSPSVEPSSTVVSLEWLDVQPAIGTKVSDYVLHHKKVDEYTDTDLYTGESLSFADDLLSGLATSCVAAGRSHGDVPETSLYSVIFKCLEPDGLYKKAHLILRRLEKVSSHCSTLLRSAYIQSRTETMPYLFCRSEEVRPPGMVWYSILKDTKVTCEEKMVSMLRNTYGESKGR", "length": 1095, "header": "tr|A0A8V1AI47-1|A0A8V1AM31_CHICK Computationally mapped isoform of Astrotactin-2 OS=Gallus gallus OX=9031 GN=ASTN2 PE=3 SV=1 CANONICAL=A0A8V1AM31-1" }, "locus": { "chromosome": "17", "start_pos": 4123409, "end_pos": 3900512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069932.1", "url": "https://www.ensembl.org/id/ENSGALT00010069932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043058.1", "url": "https://www.ensembl.org/id/ENSGALP00010043058.1" } ] } }, { "isoform_ac": "A0A8V1AKB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31/entry#A0A8V1AKB4-1", "sequence": { "sequence": "MAAPPRRRSASPAPLPPVPPALLVLAVLLGGGPGAAAVAAAAASREPPGPCRVKTVTVSTLPVLRENDISWSGAPPPAAADSRLLLFVRSELPGRVAVQDDLDNTELPFFTLEMSGTVADISLVHWKQQWLENGTLYFHVSMSSAEQLSRATPPSLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWHKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRNSRLQAHNSVIGVPIRETPILDDYEDEEEEETPQRAEPSTREDEFGSQVTRTLESLGRGGEEKGWGWGCFEVLSDTIILCFSDLFSSVTSGGIGFGRAKGNSGSEADDETQLTFYTEQYRSRRRSKGSMKSPVNKTALTLIAVSSCILAMVCGSQLSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDQETGKGGECSCHEGYAPDPMHRHLCVRTDWGHSEGPWPYTTLERGYDLVTGEQAPEKILRSTYSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSTGCVCPEDLRPMKDGTGCYDYSKGIDCSDGFNGGCEQLCLQQTLPLPHDPSSSTIFMFCGCVEEYKLAPDGKSCLMLSDICEGPKCLKSDAKFNDTLFGEMLHGYNNRSQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGTNIKYDEAMGYPMVQHWRVRSNLYRVKLSSITLSSGFANILKILNKDSSREELLSFIQQFGSHYIAEALYGSEFSCTIHFPSKKVQQQLWLQYQKGEEGSALSAACFHCSLPWFTPSPAAMLSDDHLISGVEIHCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYALIQDNDTRQVSALMSSYWCSGKGDVIEDWCRCDLNAFDENGLPNCSPLPQPVLRLSPSVEPSSTVVSLEWLDVQPAIGTKVSDYVLHHKKVDETTFFISHEVSSHNNPVVSDQEMKTFFFHFLPFRFTLYAVDTRGRHSELSTVTLRTACPLVDDSKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLEKVSSHCSTLLRSAYIQSRTETMPYLFCRSEEVRPPGMVWYSILKDTKVTCEEKMVSMLRNTYGESKGR", "length": 1251, "header": "tr|A0A8V1AKB4-1|A0A8V1AM31_CHICK Computationally mapped isoform of Astrotactin-2 OS=Gallus gallus OX=9031 GN=ASTN2 PE=3 SV=1 CANONICAL=A0A8V1AM31-1" }, "locus": { "chromosome": "17", "start_pos": 4161436, "end_pos": 3900512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069931.1", "url": "https://www.ensembl.org/id/ENSGALT00010069931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043057.1", "url": "https://www.ensembl.org/id/ENSGALP00010043057.1" } ] } }, { "isoform_ac": "A0A8V1AM31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31/entry#A0A8V1AM31-1", "sequence": { "sequence": "MAAPPRRRSASPAPLPPVPPALLVLAVLLGGGPGAAAVAAAAASREPPGPCRVKTVTVSTLPVLRENDISWSGAPPPAAADSRLLLFVRSELPGRVAVQDDLDNTELPFFTLEMSGTVADISLVHWKQQWLENGTLYFHVSMSSAEQLSRATPPSLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWHKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRNSRLQAHNSVIGVPIRETPILDDYEDEEEEETPQRAEPSTREDEFGSQVTRTLESLGRGGEEKPDYEKKAPEVTQETVESLMQKFKESFRTNTPIEIGQLQPALRSTSVGRRKRRSRPRGGIGFGRAKGNSGSEADDETQLTFYTEQYRSRRRSKGSMKSPVNKTALTLIAVSSCILAMVCGSQLSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDQETGECSCHEGYAPDPMHRHLCVRTDWGHSEGPWPYTTLERGYDLVTGEQAPEKILRSTYSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSTGCVCPEDLRPMKDGTGCYDYSKGIDCSDGFNGGCEQLCLQQTLPLPHDPSSSTIFMFCGCVEEYKLAPDGKSCLMLSDICEGPKCLKSDAKFNDTLFGEMLHGYNNRSQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIKYDEAMGYPMVQHWRVRSNLYRVKLSSITLSSGFANILKILNKDSSREELLSFIQQFGSHYIAEALYGSEFSCTIHFPSKKVQQQLWLQYQKETTELGNKKELKSMPFITYLSGLLTAQMLSDDHLISGVEIHCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYALIQDNDTRQAFKGALMSSYWCSGKGDVIEDWCRCDLNAFDENGLPNCSPLPQPVLRLSPSVEPSSTVVSLEWLDVQPAIGTKVSDYVLHHKKVDEYTDTDLYTGESLSFADDLLSGLATSCVAAGRSHGDVPETSLYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDSKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLEKVSSHCSTLLRSAYIQSRTETMPYLFCRSEEVRPPGMVWYSILKDTKVTCEEKMVSMLRNTYGESKGR", "length": 1303, "header": "tr|A0A8V1AM31-1|A0A8V1AM31_CHICK Isoform 1 of Astrotactin-2 OS=Gallus gallus OX=9031 GN=ASTN2 PE=3 SV=1 CANONICAL=A0A8V1AM31-1" }, "locus": { "chromosome": "17", "start_pos": 4161436, "end_pos": 3900512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069929.1", "url": "https://www.ensembl.org/id/ENSGALT00010069929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043055.1", "url": "https://www.ensembl.org/id/ENSGALP00010043055.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 965, "start_aa": "Thr", "end_pos": 965, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr965", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417242", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417242", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYU3-1", "protein_name": "Astrotactin-2", "gene_name": "Astn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAGARRSPGPGLGLRGRPRLRFHPGPPPPPPLPLLLLFLLLLPPPPLLAGATAAAASREPDSPCRLKTVTVSTLPALRESDIGWSGARAGAAAGAGAGTGAGAGASAAAAAAAAASPGSAGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQLHILHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSTRLQAHNSVIGVPIRETPILDDYDYEEEEDPPRRANHVSREDEFDSQMTHALDSLGRPGEEKVEFEKKGGISFGRTKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGNQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCIRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTMPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCDGPKCLKSDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLSAGFTNVLKILTKESSRDELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKNALMSSYWCSGKGDVIDDWCRCDLSAFDASGLPNCSPLPQPVLRLSPTVEPSSTVVSLEWIDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVDTIPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGETKGR", "length": 1302 }, "evidence": [ { "id": "A0A8V1AM31", "url": "https://omabrowser.org/oma/group/A0A8V1AM31/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SMI1-1", "protein_name": "Astrotactin-2", "gene_name": "ASTN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAGARRSTGPSSGLRGRLRLGFHPAPPPLLLLFLLLLPPPQLLAGATAAASREPDSPCRLKTVTVSTLPALRESDIGWSGTRAGSGTGTGTGAGAAAAAAAASPGSAGSTGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLARATAPTLQEPSEIVEEQMHIVHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQAHNSVIGVPIRETPILDDYDYEEDEDPPRRANHVSREDEFGSQVTHTLDSLGRSGEEKGDFEKKGGISFGRTKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGSQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCEGPKCLKADSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLSAGFTSVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDASGLPNCSPLPQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAHIQSRVDTVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGESKGR", "length": 1289 }, "evidence": [ { "id": "A0A8V1AM31", "url": "https://omabrowser.org/oma/group/A0A8V1AM31/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75129-1", "protein_name": "Astrotactin-2", "gene_name": "ASTN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAGARLSPGPGSGLRGRPRLCFHPGPPPLLPLLLLFLLLLPPPPLLAGATAAASREPDSPCRLKTVTVSTLPALRESDIGWSGARAGAGAGTGAGAAAAAASPGSPGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIGVPIRETPILDDYDCEEDEEPPRRANHVSREDEFGSQVTHTLDSLGHPGEEKVDFEKKAAAEATQETVESLMQKFKESFRANTPIEIGQLQPPLRSTSAGKRKRRSKSRGGISFGRAKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGSQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCEGPKCLKPDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGESKGR", "length": 1339 }, "evidence": [ { "id": "A0A8V1AM31", "url": "https://omabrowser.org/oma/group/A0A8V1AM31/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80Z10-1", "protein_name": "Astrotactin-2", "gene_name": "Astn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGARRSPGRGLGLRGRPRLGFHPGPPPPPPPPLLLLFLLLLPPPPLLAGATAAAASREPDSPCRLKTVTVSTLPALRESDIGWSGARTGAAAGAGAGTGAGAGAAAAAASAASPGSAGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIGVPIRETPILDDYDYEEEEEPPRRANHVSREDEFGSQMTHALDSLGRPGEEKVEFEKKAAAEATQETVESLMQKFKESFRANTPVEIGQLQPASRSSTSAGKRKRRNKSRGGISFGRTKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGNQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPDTGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDTTSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCEGPKCLKPDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLSAGFTNVLKILTKESSRDELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKNALMSSYWCSGKGDVIDDWCRCDLSAFDASGLPNCSPLPQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQTAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVDTIPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGETKGR", "length": 1352 }, "evidence": [ { "id": "A0A8V1AM31", "url": "https://omabrowser.org/oma/group/A0A8V1AM31/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "cell pole", "id": "GO:0060187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060187", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "neuron cell-cell adhesion", "id": "GO:0007158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "inositol 1,3,4,5 tetrakisphosphate binding", "id": "GO:0043533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043533", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1025, "end_pos": 1027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 984, "end_pos": 986, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AM31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM31" }, { "id": "SM00457", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00457" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MACPF", "eco_id": "ECO_0000259", "start_pos": 815, "end_pos": 999, "start_aa": "Tyr", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 965 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1025, "end_pos": 1027 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 984, "end_pos": 986 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQ58-1", "uniprot_ac": "E1BQ58", "uniprot_id": "E1BQ58_CHICK", "mass": { "chemical_mass": 28567.0, "monoisotopic_mass": 28567.0 }, "refseq": { "ac": "NP_001292602", "name": "ribosome-recycling factor, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292602" }, "gene_names": [ { "name": "MRRF", "type": "recommended", "evidence": [ { "id": "E1BQ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ58" } ] }, { "name": "MRRFP1", "type": "synonym", "evidence": [ { "id": "NP_001292602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292602" } ] }, { "name": "MRRF", "type": "synonym", "evidence": [ { "id": "NP_001292602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292602" } ] } ], "protein_names": [ { "name": "Ribosome-recycling factor, mitochondrial", "type": "recommended", "evidence": [ { "id": "E1BQ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ58/entry#names_and_taxonomy" } ] }, { "name": "Ribosome-releasing factor, mitochondrial", "type": "synonym", "evidence": [ { "id": "E1BQ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ58/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial ribosome recycling factor pseudogene 1", "type": "synonym", "evidence": [ { "id": "NP_001292602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292602" } ] }, { "name": "ribosome-recycling factor, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001292602", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292602" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01045022.1, HAEK01054362.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000308.1. On Mar 27, 2015 this sequence version replaced XP_415395.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292602", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292602" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQ58", "url": "https://www.uniprot.org/uniprotkb/E1BQ58" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRRF", "url": "https://www.uniprot.org/uniprotkb/E1BQ58", "locus": { "chromosome": "17", "start_pos": 9365225, "end_pos": 9353910, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028366", "url": "https://www.ensembl.org/id/ENSGALG00010028366" } ] } } ], "crossref": [ { "id": "E1BQ58", "url": "https://alphafold.ebi.ac.uk/entry/E1BQ58", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001333", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001333", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417110", "url": "https://www.ncbi.nlm.nih.gov/gene/417110", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417110", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417110", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNPMNNG", "url": "https://omabrowser.org/oma/group/FNPMNNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AG41", "url": "https://www.orthodb.org/?gene=A0A8V1AG41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIE0", "url": "https://www.orthodb.org/?gene=A0A8V1AIE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQ58", "url": "https://www.orthodb.org/?gene=E1BQ58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20982", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20982", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20982:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20982:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292602", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292602", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AG41", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AG41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ58", "url": "https://www.uniprot.org/uniprotkb/E1BQ58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ58-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMALRCFRHLHSLLHCSSLAVVRQLPQPPARCTPLLLDGCRHCAHPLLLARPLATKKAKGKGQTQAKVNISAALVEDIINLEETNTDMQAVVEALKEDFNRNLNVRTSQGALDHIIVTTKDGKFPLNQLGQISQKSPQLIVVNMTSFPESTAAAMKAIRESGMNLNPEVDGTLIRVPVPKVTREHRESLAKLAKQSTNKSKEALRKVRSKSVNQVKKFKSKVSEDTIWLLEKQIQQMADSAAAEMDKLLAAKTKELLG", "length": 259, "header": "tr|E1BQ58-1|E1BQ58_CHICK Isoform 1 of Ribosome-recycling factor, mitochondrial OS=Gallus gallus OX=9031 GN=MRRF PE=1 SV=1 CANONICAL=E1BQ58-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AG41-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ58/entry#A0A8V1AG41-1", "sequence": { "sequence": "MAMALRCFRHLHSLLHCSSLAVVRQLPQPPARCTPLLLDGCRHCAHPLLLARPLATKKAKGKGQTQAKVNISAALVEDIINLEETNTDMQAVVEALKEDFNRNLNVRTSQGALDHIIVTTKDGKFPLNQLGQISQKSPQLIVVNMTSFPESTAAAMKAIRESGMNLNPEVDGTLIRVPVPKKFLAFEIQKLFLPTKTRCVGDQMWPALFSLRVCSCRVLGKEHPGSAVLQPPVAGWGRKRGDVTVGQCTALHAPLCAQRAVLCVAQQDGPGHTAGFEPTALYLQRQQWSWGLILIPAGGGQPFPVSVSHFDSKEGGSCSSY", "length": 321, "header": "tr|A0A8V1AG41-1|E1BQ58_CHICK Computationally mapped isoform of Ribosome-recycling factor, mitochondrial OS=Gallus gallus OX=9031 GN=MRRF PE=1 SV=1 CANONICAL=E1BQ58-1" }, "locus": { "chromosome": "17", "start_pos": 9360856, "end_pos": 9354507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068722.1", "url": "https://www.ensembl.org/id/ENSGALT00010068722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042226.1", "url": "https://www.ensembl.org/id/ENSGALP00010042226.1" } ] } }, { "isoform_ac": "A0A8V1AIE0-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ58/entry#A0A8V1AIE0-1", "sequence": { "sequence": "MAMALRCFRHLHSLLHCSSLAVVRQLPQPPARCTPLLLDGCRHCAHPLLLARPLATKKAKGKGQTQAKVNISAALVEDIINLEETNTDMQAVVEALKEDFNRNLNVRTSQGALDHIIVTTKDGKFPLNQLGQISQKSPQLIVVNMTSFPESTAAAMKAIRESGMNLNPEVDGTLIRVPVPKSKADLPFPREICLMSCHSSAAELLLLSVPFPWQLAPRSPTSNSFAVCTTCPAGLPLMGSSPVGQQNCSGFRPLQTRRTVSIFKTF", "length": 266, "header": "tr|A0A8V1AIE0-1|E1BQ58_CHICK Computationally mapped isoform of Ribosome-recycling factor, mitochondrial OS=Gallus gallus OX=9031 GN=MRRF PE=1 SV=1 CANONICAL=E1BQ58-1" }, "locus": { "chromosome": "17", "start_pos": 9359353, "end_pos": 9354507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068721.1", "url": "https://www.ensembl.org/id/ENSGALT00010068721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042225.1", "url": "https://www.ensembl.org/id/ENSGALP00010042225.1" } ] } }, { "isoform_ac": "E1BQ58-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ58/entry#E1BQ58-1", "sequence": { "sequence": "MAMALRCFRHLHSLLHCSSLAVVRQLPQPPARCTPLLLDGCRHCAHPLLLARPLATKKAKGKGQTQAKVNISAALVEDIINLEETNTDMQAVVEALKEDFNRNLNVRTSQGALDHIIVTTKDGKFPLNQLGQISQKSPQLIVVNMTSFPESTAAAMKAIRESGMNLNPEVDGTLIRVPVPKVTREHRESLAKLAKQSTNKSKEALRKVRSKSVNQVKKFKSKVSEDTIWLLEKQIQQMADSAAAEMDKLLAAKTKELLG", "length": 259, "header": "tr|E1BQ58-1|E1BQ58_CHICK Isoform 1 of Ribosome-recycling factor, mitochondrial OS=Gallus gallus OX=9031 GN=MRRF PE=1 SV=1 CANONICAL=E1BQ58-1" }, "locus": { "chromosome": "17", "start_pos": 9364216, "end_pos": 9354507, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068723.1", "url": "https://www.ensembl.org/id/ENSGALT00010068723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042227.1", "url": "https://www.ensembl.org/id/ENSGALP00010042227.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417110", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417110", "resource": "KEGG Pathway" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SLQ7-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "MRRF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALGLRCFRLVHPAFCNSLAALTRPVSEVTLKTVSGSRNNHGQYMAYPAVPVCHFATKKAKAKGKGQSQTRMNLNTALVEDIISLEEVDEEMKSVIEALKDNFNKTVNIRTSPGSLDQITVVTADGKLALNQIGQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPDVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKESLRKVRTNAMNKLKKSKDKASEDTLRLIEKQISQMADDTVAELERHLAVKTKELLG", "length": 262 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X7D8-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "MRRF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTHYARAAAPPRDVTTPAPPAPPPPPPWSRESFPNNPGASCGYSQGLSSVMALGLRCFRLVHPAFCNSLAALTRPVSEVTLQTVRGRQNDHGQCMAYAAVPVRHFATKKAKAKGKGQSQTRMNLNTALVEDIINLEEVDEEMKSVIEALKDNFNKTVNIRTSPGALDNITVVTADGKLPLNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKDSLRKVRTNAINKVKKSKDKASEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG", "length": 312 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55G90-1", "protein_name": "Ribosome recycling factor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRGINRFSGCFVRSIGNNSNQQQQTYRGIISVAKTTTTSSFQRRSPFSIFNENSVMTLRAKKSGGGGGGKSNSKDDEVFTPWKQVDISSVSSQGDKTIEYVSRELGNIRFGRVGPELLERINVETPSGNLLLPHMAMITIKDSLTLNITLYDSSLLSNVERALTNSGLGLNPQTFDTTIRVSLPKPTQDLRQKLIKQVNTISEDAKVSIRRHRKDGMDILKRYKLTKDDEKTLEKNIQKITDDYIKSITKITETKLKEINSN", "length": 263 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RKI9-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "Mrrf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALGIRCFRLLHPAFSSYLADLSRPVSEVPMKTVRGRQRDHIQYSAHPAVPVRQFATKKAKAKGKGQPQARVNINTALVEDIISLEEVDEDMKSVMEALKDNFNKTLNIRTAPGSLDHITVVTADGKLALNQIGQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMNKLKKSKDKTSEDTIRLIEKQISQMADDTVAELDRHLAAKTKELLG", "length": 262 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96E11-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "MRRF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALGLKCFRMVHPTFRNYLAASIRPVSEVTLKTVHERQHGHRQYMAYSAVPVRHFATKKAKAKGKGQSQTRVNINAALVEDIINLEEVNEEMKSVIEALKDNFNKTLNIRTSPGSLDKIAVVTADGKLALNQISQISMKSPQLILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPQVTREHREMLVKLAKQNTNKAKDSLRKVRTNSMNKLKKSKDTVSEDTIRLIEKQISQMADDTVAELDRHLAVKTKELLG", "length": 262 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6S7-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "Mrrf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGIRCFRLLHPAFRSYHAALTRPVSEVSMKTVSGRQHGHRQYSAYPAVPVRHFATKKAKAKGKGQPQARVTVNRALVEDIISLEEVDEDMKSVVEALKDNFNKTLNIRTAPGSLDHITVVTADGKVALNQIGQISMKSPQVILVNMASFPECTAAAIKAIRESGMNLNPEVEGTLIRVPIPKVTREHREMLVKLAKQNTNKAKENLRKVRTNAMNKLKKSKDKTSEDTIRLIEKQISQMADDTVAELDQHLAAKTKELLG", "length": 262 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M1X0-1", "protein_name": "Ribosome-recycling factor, chloroplastic", "gene_name": "RRF", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAASFSSTAPTTPVLRFRANYSKPLLSLPDSCLRIISSAISPSTRLIACSFKTDKLPLGAGVNLSGGPVVKRSLQKRLVIRSATIEEIEAEKSAIETDVKSKMEKTIETLRTSFNSIRTGRSNAAMLDKIEVEYYGSPVSLKSIAQISTPDGSSLLLQPYDKSSLKAIEKAIVNSDLGVTPNNDGDVIRLSLPPLTSDRRKELSKVVAKQSEEGKVALRNIRRDALKSYDKLEKEKKLSEDNVKDLSSDLQKLIDVYMKKIEELYKQKEKELMKV", "length": 275 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VSW4-1", "protein_name": "Ribosome-recycling factor, mitochondrial", "gene_name": "mRRF1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRSALHLAALGVRQTRVSSSSPKLPLILQNNLENTKYLQVARDYAKGKDKKKEKGGKGKPGKVEINEQQLREILNFDGLNSQMQKSVMQMKEDFVKHLSLRSTSGAIDTLRIKVDGQEHELQELAQISRKNPKTIIVNMIGFPQTIPDVLKAIEKSGMNLNPQQDGTTLFIPIPKVTKEHRENLSKNAKALFVKYRDAIRGVQNEHIRKLKKQPELGKDDAFAAQAQVTAIADRFISEADKLLASKQKELLGD", "length": 254 }, "evidence": [ { "id": "E1BQ58", "url": "https://omabrowser.org/oma/group/E1BQ58/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosome disassembly", "id": "GO:0032790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032790", "evidence": [ { "database": "UniProtKB", "id": "E1BQ58", "url": "https://www.uniprot.org/uniprotkb/E1BQ58" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1BQ58", "url": "https://www.uniprot.org/uniprotkb/E1BQ58" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BQ58", "url": "https://www.uniprot.org/uniprotkb/E1BQ58" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ribosomal large subunit binding", "id": "GO:0043023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043023", "evidence": [ { "database": "UniProtKB", "id": "E1BQ58", "url": "https://www.uniprot.org/uniprotkb/E1BQ58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ58" }, { "id": "PF01765", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01765" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosome recycling factor", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 258, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMB3-1", "uniprot_ac": "A0A8V1AMB3", "uniprot_id": "A0A8V1AMB3_CHICK", "mass": { "chemical_mass": 128766.0, "monoisotopic_mass": 128766.0 }, "refseq": { "ac": "XP_415742", "name": "rabankyrin-5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415742" }, "gene_names": [ { "name": "ANKFY1", "type": "recommended", "evidence": [ { "id": "A0A8V1AMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ] }, { "name": "ANKFY1", "type": "synonym", "evidence": [ { "id": "XP_415742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415742" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and FYVE domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3/entry#names_and_taxonomy" } ] }, { "name": "rabankyrin-5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415742" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415742.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415742", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415742" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKFY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3", "locus": { "chromosome": "19", "start_pos": 3687451, "end_pos": 3655646, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029163", "url": "https://www.ensembl.org/id/ENSGALG00010029163" } ] } } ], "crossref": [ { "id": "A0A8V1AMB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15728", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15728", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18303", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18303", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18501", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18501", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417494", "url": "https://www.ncbi.nlm.nih.gov/gene/417494", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WGLEQVV", "url": "https://omabrowser.org/oma/group/WGLEQVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB09", "url": "https://www.orthodb.org/?gene=A0A8V1AB09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGC7", "url": "https://www.orthodb.org/?gene=A0A8V1AGC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMB3", "url": "https://www.orthodb.org/?gene=A0A8V1AMB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415742", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415742", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEEEVAKLEKHLMLLRQEYVKLQKKLADTERRCNLLAAQANQDNASDTFISRLLAIVAELYQQEQYSDLKIKVRDKHISAHKFVLAARSDAWSLANLASTEELDLSDADPEVTMAMLRWIYTDELELREDDIFLTELMKLANKFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMFKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNELDQNGDLALDLALSQRLESIATTLVNYKADVDRADKRGWSLLHKAIQRGDKFAANFLIKNGARVNAATLGDQETPLHLVSSYSPKKHSPDVMAEMAQIAESLLQAGANPNMQDSKGRTPLHMSIVVRNEPVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDAPVVNGTSFDENSFAARLIQRGSNTDAPDTVTGNCLLQRAAGAGNEAASLFLATHGAKVNHQNKWGETPLHTACRHGLANLTAELLQQGANPNIQTAEVAPGQKDASSPTAESVYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKNQLPLVVDAICTRGADMSVPDEKGNPPLWLALENNLEDIASTLVRHGCDSTCWGSGPSGCLQTLLHRAIDENSEQIACFLIRSGCDVNSPRKPGPNGEGEEEAHDGQTPLHLAACWGLEEVIQCLLEFGANVNAQDAEGRTPIHVAISNQHNVIIQLMISHPEIKLNVRDRQGMTPFACAMTYKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAQVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECNVDAEAFNIRGQSPMHILGQYGKDNAAAICDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRAGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLTKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS", "length": 1167, "header": "tr|A0A8V1AMB3-1|A0A8V1AMB3_CHICK Isoform 1 of Ankyrin repeat and FYVE domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFY1 PE=1 SV=1 CANONICAL=A0A8V1AMB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3/entry#A0A8V1AB09-1", "sequence": { "sequence": "MLEEVAKLEKHLMLLRQEYVKLQKKLADTERRCNLLAAQANQDNASDTFISRLLAIVAELYQQEQYSDLKIKVRDKHISAHKFVLAARSDAWSLANLASTEELDLSDADPEVTMAMLRWIYTDELELREDDIFLTELMKLANKFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMFKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNELDQNGDLALDLALSQRLESIATTLVNYKADVDRADKRGWSLLHKAIQRGDKFAANFLIKNGARVNAATLGDQETPLHLVSSYSPKKHSPDVMAEMAQIAESLLQAGANPNMQDSKGRTPLHMSIVVRNEPVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDAPVVNGTSFDENSFAARLIQRGSNTDAPDTVTGNCLLQRAAGAGNEAASLFLATHGAKVNHQNKWGETPLHTACRHGLANLTAELLQQGANPNIQTAEVAPGQKDASSPTAESVYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKNQLPLVVDAICTRGADMSVPDEKGNPPLWLALENNLEDIASTLVRHGCDSTCWGSGPSGCLQTLLHRAIDENSEQIACFLIRSGCDVNSPRKPGPNGEGEEEAHDGQTPLHLAACWGLEEVIQCLLEFGANVNAQDAEGRTPIHVAISNQHNVIIQLMISHPEIKLNVRDRQGMTPFACAMTYKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAQVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECNVDAEAFNIRGQSPMHILGQYGKDNAAAICDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRAGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLTKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS", "length": 1166, "header": "tr|A0A8V1AB09-1|A0A8V1AB09_CHICK Computationally mapped isoform of Ankyrin repeat and FYVE domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFY1 PE=1 SV=1 CANONICAL=A0A8V1AMB3-1" }, "locus": { "chromosome": "19", "start_pos": 3683837, "end_pos": 3659453, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070473.1", "url": "https://www.ensembl.org/id/ENSGALT00010070473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043164.1", "url": "https://www.ensembl.org/id/ENSGALP00010043164.1" } ] } }, { "isoform_ac": "A0A8V1AGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3/entry#A0A8V1AGC7-1", "sequence": { "sequence": "MAEEEVAKLEKHLMLLRQEYVKLQKKLADTERRCNLLAAQANQDNASDTFISRLLAIVAELYQQEQYSDLKIKVRDKHISAHKFVLAARSDAWSLANLASTEELDLSDADPEVTMAMLRWIYTDELELREDDIFLTELMKLANKFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMFKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNELDQNGDLALDLALSQRLESIATTLVNYKADVDRADKRGWSLLHKAIQRGDKFAANFLIKNGARVNAATLGDQETPLHLVSSYSPKKHSPDVMAEMAQIAESLLQAGANPNMQDSKGRTPLHMSIVVRNEPVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDAPVVNGTSFDENSFAARLIQRGSNTDAPDTVTGNCLLQRAAGAGNEAASLFLATHGAKVNHQNKWGETPLHTACRHGLANLTAELLQQGANPNIQTAEVAPGQKDASSPTAESVYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKNQLPLVVDAICTRGADMSVPDEKGNPPLWLALENNLEDIASTLVRHGCDSTCWGSGPSGCLQTLLHRAIDENSEQIACFLIRSGCDVNSPRKPGPNGEGEEEAHDGQTPLHLAACWGLEEVIQCLLEFGANVNAQDAEGRTPIHVAISNQHNVIIQLMISHPEIKLNVRDRQGMTPFACAMTYKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAQVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECNVDAEAFNIRGQSPMHILGQYGKDNAAAICDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRAGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLTKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKLESAKD", "length": 1150, "header": "tr|A0A8V1AGC7-1|A0A8V1AMB3_CHICK Computationally mapped isoform of Ankyrin repeat and FYVE domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFY1 PE=1 SV=1 CANONICAL=A0A8V1AMB3-1" }, "locus": { "chromosome": "19", "start_pos": 3686776, "end_pos": 3655669, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070475.1", "url": "https://www.ensembl.org/id/ENSGALT00010070475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043166.1", "url": "https://www.ensembl.org/id/ENSGALP00010043166.1" } ] } }, { "isoform_ac": "A0A8V1AMB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3/entry#A0A8V1AMB3-1", "sequence": { "sequence": "MAEEEVAKLEKHLMLLRQEYVKLQKKLADTERRCNLLAAQANQDNASDTFISRLLAIVAELYQQEQYSDLKIKVRDKHISAHKFVLAARSDAWSLANLASTEELDLSDADPEVTMAMLRWIYTDELELREDDIFLTELMKLANKFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLLNYCAEIIASHWDDLRKEDFSSMSAQLLYKMFKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNELDQNGDLALDLALSQRLESIATTLVNYKADVDRADKRGWSLLHKAIQRGDKFAANFLIKNGARVNAATLGDQETPLHLVSSYSPKKHSPDVMAEMAQIAESLLQAGANPNMQDSKGRTPLHMSIVVRNEPVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDAPVVNGTSFDENSFAARLIQRGSNTDAPDTVTGNCLLQRAAGAGNEAASLFLATHGAKVNHQNKWGETPLHTACRHGLANLTAELLQQGANPNIQTAEVAPGQKDASSPTAESVYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKNQLPLVVDAICTRGADMSVPDEKGNPPLWLALENNLEDIASTLVRHGCDSTCWGSGPSGCLQTLLHRAIDENSEQIACFLIRSGCDVNSPRKPGPNGEGEEEAHDGQTPLHLAACWGLEEVIQCLLEFGANVNAQDAEGRTPIHVAISNQHNVIIQLMISHPEIKLNVRDRQGMTPFACAMTYKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAQVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECNVDAEAFNIRGQSPMHILGQYGKDNAAAICDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRAGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLTKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS", "length": 1167, "header": "tr|A0A8V1AMB3-1|A0A8V1AMB3_CHICK Isoform 1 of Ankyrin repeat and FYVE domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFY1 PE=1 SV=1 CANONICAL=A0A8V1AMB3-1" }, "locus": { "chromosome": "19", "start_pos": 3683837, "end_pos": 3655669, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070474.1", "url": "https://www.ensembl.org/id/ENSGALT00010070474.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043165.1", "url": "https://www.ensembl.org/id/ENSGALP00010043165.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IK06-1", "protein_name": "Rabankyrin-5 isoform X1", "gene_name": "ankfy1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEEVQKLQKHLALLRQEYVKMQQKLVETERRCSVLAAQASVPGSSSQASDSFISRLLAIVSDLYQQEQYSDLKVKIGDQRLSAHKFVLAARSEIWSLANLASTSELDLSDAKPEVAMAMLRWTYTDDLELNGNDGFLIDLMKLANRFQLHLLRERCEKGVMSSVNVRNCIRFYQTAEELDAATLMNYCGEIIASHWDDLRKEDFSTMDAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDAQLPGKLNELDNNGDLALDLALSKKLESIATTLVNNKADVDMVDQSGWSLLHKAIQRGDEFASTFLIRHSAQVNAATVGAVETPLHLVCSFSPKKHSGEVMAGMARIAEALLKAGANPNMQNSKGRTPLHEAVVSGNEPVFNQLLQCKQLDLELKDHEGSTALWLALQYITVASDPSVNPFEDEAPVVNGTSFDENSFAARLIQRGSNPDAPDTNGNCLMQRAAVAGSEAAAIFLATHGAKVNHTNKWGETPLHTACRCGLAGLTVELLQQGANPNLQTDIALPGGVEKSQGVSQQSPLHLAIVHNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSMDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIKRQDSKSALFLLEHQADINVRTQEGQTALQLAISNQLPLVVDAICTRGADMSVVNEKGDPPLWLALENGLEDIASTLVRHGCDATCWSSGPGGCQQTLLHRAIDENNEVTACFLIRSGCDVNSSRRPGPNGEGDEEARDGQCPLHLAASWGLEEVAQCLLEFGANVNAQDSEGRAPIHVAISNQQSVIIQLLISHPEIRLNIRDRQGMTPFACAMTHKNNKAAEAILKREPGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDSAKLSPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLSTICSVLIENGVDFAAVDENGNNALHLAVMQGRLNNVRALLTESNVDAEAYNLRGQSPMHVLGQYGKENAAAIFELFLECMPEYPLDKPDNEGNTVLLLAYMKGNANLCRAIVRAGARLGVTNNQGINIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECITKFGVTTRKHHCRHCGRLLCHKCSIKEIPIIKFDLNKPVRVCDICFDVLTLGGVS", "length": 1167 }, "evidence": [ { "id": "A0A8V1AMB3", "url": "https://omabrowser.org/oma/group/A0A8V1AMB3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I5Y6Q8-1", "protein_name": "Ankyrin repeat and FYVE domain-containing protein 1", "gene_name": "Ankfy1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFAMETFFIFLAEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCTLLAAQANKENSSESFISRLLAIVAGLYEQEQYSDLKIKVGGRHISAHKFVLAARSDSWSLANLSSTAELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSLSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSYKADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATVGAQETPLHLVALYSSKKYSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHLSIMARNEYVFNQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDLPVVNGTSFDENSFAARLIQRGSNTDAPDTMTGNCLLQRAAGAGNEAAALFLATSGAHANHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPVPKESPVLMGSADGIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDRETALQLAIKNQLPLVVDAICTRGADMSVPDEKGNPPLWLALASNLEDIASTLVRHGCDATCWGPGPSGCLQTLLHRAIDENNESTACFLIRSGCDVNSPRQPGTDGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTAVHVAISNQHSVIIQLLISHPSIELSIRDRQGLTPFACAMTYKNNKAAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDATKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRALLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRSGVRLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS", "length": 1179 }, "evidence": [ { "id": "A0A8V1AMB3", "url": "https://omabrowser.org/oma/group/A0A8V1AMB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7PLP5-1", "protein_name": "Rabankyrin-5", "gene_name": "BEST:GM10035", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKTGSNETFSVLKMEKILAVQSDEYTKLQRCYVELQRKYNENIASSENEESGLSSFLSRLSLTVASLFDKNTYADIYIRSQTRVFPAHKIVLHARSEKWGNDLLSNIQQLDWSDLNEDVVLSLLRWIYTDLIDLQNDGLALDLLKAAHRFGLPSLLGICERALVTSVGVRSCIRFYCVAEEVGASTLLEYCSSIISTHWDDLTTDDFQHMSGPLLFEMLKTKTKHPLHAAVRLLREDVVSLCIQKYGNSLVNTFSENGILPLEMALSSKNAKIAKSLVDNGMANINAVNMEGFSLLKSALKNGDAFSANFLLDQNCLLDLPSKPSSDTALHIICNYGPDNTPEIMEVVKKILQRQLNINIQNIKGETPLHIAIARRNVEMVKLLLKVPNIDINLRTYDEKCALELSLSMGDHEFLIASILLSMGARTDRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLTALHIAALNNMPNLVKKLIVNGASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTTLVPTLIRGGSDVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGESPLWSALEKGYEDVAKILVRHGIDTDCWDEGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSSRQPGPNGEGGDEAQDKASPLHLCCHWGQTKVLQTLIDHGANVNLIDAESKSPLHVAIESQYDEIISILLCHPDIDLKLRDKSGNTPFATALDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFLLAIQVDVNSRVHDANQSSPLHLAAASQNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDATDADGNNALHIAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHELCRVVEDSTAGLICELFLESMPKYPINIPDMDGNTPLLLSFMRGQSPLCKILVKAGACLGTENKDGINIFNFKLATDQLLHNLLDQLPQESPWAESDYCQHCTNRFTITMRKHHCRHCGRVLCSKCSCNDVPILKFGINKPVRVCTVCFNVLQCGNGSLS", "length": 1124 }, "evidence": [ { "id": "A0A8V1AMB3", "url": "https://omabrowser.org/oma/group/A0A8V1AMB3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q810B6-1", "protein_name": "Ankyrin repeat and FYVE domain-containing protein 1", "gene_name": "Ankfy1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCTLLAAQANKENSNESFISRLLAIVAGLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTEEIDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSLSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNETDHNGDLALDLALSRRLESIATTLVSHKADVDMVDKNGWSLLHKGIQRGDLFASTFLIKNGALVNAATAGAQETPLHLVALYSPKKYSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHLSIMARNDCVFSQLLQCKQLDLELKDHEGSTALWLAVQYITVSSDQSVNPFEDLPVVNGTSFDENSFAARLIQRGSNTDAPDVMTGNCLLQRAAGAGNEAAALFLATSGAHANHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPVPKESPVLMSSADSIYLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGASINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIKHQLPLVVDAICTRGADMSVPDEKGNPPLWLALASNLEDIASTLVRHGCDATCWGPGPSGCLQTLLHRAVDENNESTACFLIRSGCDVNSPRQPGTNGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPVHVAISNQHSVIIQLLISHPNIELSVRDRQGLTPFACAMTYKNNKAAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVQANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRALLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPEYPLDKPDAEGNTVLLLAYMKGNANLCRAIVRSGVRLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS", "length": 1169 }, "evidence": [ { "id": "A0A8V1AMB3", "url": "https://omabrowser.org/oma/group/A0A8V1AMB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2R3-1", "protein_name": "Ankyrin repeat and FYVE domain-containing protein 1", "gene_name": "ANKFY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHTDAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNALHLAVMHGRLNNIRVLLTECTVDAEAFNLRGQSPLHILGQYGKENAAAIFDLFLECMPGYPLDKPDADGSTVLLLAYMKGNANLCRAIVRSGARLGVNNNQGVNIFNYQVATKQLLFRLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICFDVLTLGGVS", "length": 1169 }, "evidence": [ { "id": "A0A8V1AMB3", "url": "https://omabrowser.org/oma/group/A0A8V1AMB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "macropinosome", "id": "GO:0044354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044354", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "endosomal vesicle fusion", "id": "GO:0034058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "positive regulation of pinocytosis", "id": "GO:0048549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048549", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" }, { "name": "Golgi to lysosome transport", "id": "GO:0090160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 130, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB3" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 1102, "end_pos": 1162, "start_aa": "Trp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 614, "end_pos": 616 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMD8-1", "uniprot_ac": "A0A8V1AMD8", "uniprot_id": "A0A8V1AMD8_CHICK", "mass": { "chemical_mass": 60949.0, "monoisotopic_mass": 60949.0 }, "refseq": {}, "gene_names": [ { "name": "ASPSCR1", "type": "recommended", "evidence": [ { "id": "A0A8V1AMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ] } ], "protein_names": [ { "name": "ASPSCR1, UBX domain containing tether for SLC2A4", "type": "synonym", "evidence": [ { "id": "A0A8V1AMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASPSCR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8", "locus": { "chromosome": "18", "start_pos": 5630665, "end_pos": 5674834, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029177", "url": "https://www.ensembl.org/id/ENSGALG00010029177" } ] } } ], "crossref": [ { "id": "A0A8V1AMD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16105", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16105", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGF7", "url": "https://www.orthodb.org/?gene=A0A8V1AGF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMD8", "url": "https://www.orthodb.org/?gene=A0A8V1AMD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46467", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46467", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46467:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46467:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AGF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGGGGAAVSVLAPSGRRVTVRVGPGTVLLQVLEEVCRKQGGSPAEYGLKFQRNVLDLTLQWRFARLPNNAKLEMVPVSCNRVGIGNTVRIALQLDDGSRLQDTFLCQQTLWELLNHFAKTREFLEQRGEFCPVCIYMRDEISGKDALEKTTLKSLGLTGGSAIVRVVMKKCSLSDQEEAVDTTAQCDEPVARPSSTEGAVDVPLPQTQTFPTVLDHGDEALSLNNCTDKQDSIRESDASLEELCPPSESKSTPFVPFFGSGQCLGDSSVSAPPLELDMPSSELPTTFSSPGGPSKPKKSKNSQELQKEQEQLVEREPLLCHPDLLEPPPADLEDLPDEFFEVTVDDVRKRLAQLQSERKRLEEAPLLTKSLREAQLKEKLERYPKVVLRVHFPDRHILQGFFRPTETVGVVRDFVRSHLADPDLPFYLFIAPPRVILNDESLTLSEAKLFPAAVIHFGSEERRDCYLKSDLLSSAVSPSAADLLMARCLSKPLAPSASSLESIVPALPEPEVGSDKKTERPEPARVHEAPQVLRRAPGKIPKWLKLPGGKR", "length": 554, "header": "tr|A0A8V1AMD8-1|A0A8V1AMD8_CHICK Isoform 1 of ASPSCR1, UBX domain containing tether for SLC2A4 OS=Gallus gallus OX=9031 GN=ASPSCR1 PE=1 SV=1 CANONICAL=A0A8V1AMD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8/entry#A0A8V1AGF7-1", "sequence": { "sequence": "MVPVSCNRVGIGNTVRIALQLDDGSRLQDTFLCQQTLWELLNHFAKTREFLEQRGEFCPVCIYMRDEISGKDALEKTTLKSLGLTGGSAIVRVVMKKCSLSDQEEAVDTTAQCDEPVARPSSTEGAVDVPLPQTQTFPTVLDHGDEALSLNNCTDKQDSIRESDASLEELCPPSESKSTPFVPFFGSGQCLGDSSVSAPPLELDMPSSELPTTFSSPGGPSKPKKSKNSQELQKEQEQLVEREPLLCHPDLLEPPPADLEDLPDEFFEVTVDDVRKRLAQLQSERKRLEEAPLLTKSLREAQLKEKLERYPKVVLRVHFPDRHILQGFFRPTETVGVVRDFVRSHLADPDLPFYLFIAPPRVILNDESLTLSEAKLFPAAVIHFGSEERRDCYLKSDLLSSAVSPSAADLLMARCLSKPLAPSASSLESIVPALPEPEVGSDKKTERPEPARVHEAPQVLRRAPGKIPKWLKLPGGKR", "length": 478, "header": "tr|A0A8V1AGF7-1|A0A8V1AMD8_CHICK Computationally mapped isoform of ASPSCR1, UBX domain containing tether for SLC2A4 OS=Gallus gallus OX=9031 GN=ASPSCR1 PE=1 SV=1 CANONICAL=A0A8V1AMD8-1" }, "locus": { "chromosome": "18", "start_pos": 5668165, "end_pos": 5633748, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070506.1", "url": "https://www.ensembl.org/id/ENSGALT00010070506.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043197.1", "url": "https://www.ensembl.org/id/ENSGALP00010043197.1" } ] } }, { "isoform_ac": "A0A8V1AMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8/entry#A0A8V1AMD8-1", "sequence": { "sequence": "MAAAGGGGAAVSVLAPSGRRVTVRVGPGTVLLQVLEEVCRKQGGSPAEYGLKFQRNVLDLTLQWRFARLPNNAKLEMVPVSCNRVGIGNTVRIALQLDDGSRLQDTFLCQQTLWELLNHFAKTREFLEQRGEFCPVCIYMRDEISGKDALEKTTLKSLGLTGGSAIVRVVMKKCSLSDQEEAVDTTAQCDEPVARPSSTEGAVDVPLPQTQTFPTVLDHGDEALSLNNCTDKQDSIRESDASLEELCPPSESKSTPFVPFFGSGQCLGDSSVSAPPLELDMPSSELPTTFSSPGGPSKPKKSKNSQELQKEQEQLVEREPLLCHPDLLEPPPADLEDLPDEFFEVTVDDVRKRLAQLQSERKRLEEAPLLTKSLREAQLKEKLERYPKVVLRVHFPDRHILQGFFRPTETVGVVRDFVRSHLADPDLPFYLFIAPPRVILNDESLTLSEAKLFPAAVIHFGSEERRDCYLKSDLLSSAVSPSAADLLMARCLSKPLAPSASSLESIVPALPEPEVGSDKKTERPEPARVHEAPQVLRRAPGKIPKWLKLPGGKR", "length": 554, "header": "tr|A0A8V1AMD8-1|A0A8V1AMD8_CHICK Isoform 1 of ASPSCR1, UBX domain containing tether for SLC2A4 OS=Gallus gallus OX=9031 GN=ASPSCR1 PE=1 SV=1 CANONICAL=A0A8V1AMD8-1" }, "locus": { "chromosome": "18", "start_pos": 5669329, "end_pos": 5633748, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070505.1", "url": "https://www.ensembl.org/id/ENSGALT00010070505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043196.1", "url": "https://www.ensembl.org/id/ENSGALP00010043196.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD8" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 384, "end_pos": 460, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 22 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 228, "end_pos": 230 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMR1-1", "uniprot_ac": "A0A8V1AMR1", "uniprot_id": "A0A8V1AMR1_CHICK", "mass": { "chemical_mass": 80565.0, "monoisotopic_mass": 80565.0 }, "refseq": { "ac": "XP_004946214", "name": "syntaxin-binding protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946214" }, "gene_names": [ { "name": "STXBP4", "type": "recommended", "evidence": [ { "id": "A0A8V1AMR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ] }, { "name": "STXBP4", "type": "synonym", "evidence": [ { "id": "XP_004946214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946214" } ] } ], "protein_names": [ { "name": "Syntaxin binding protein 4", "type": "synonym", "evidence": [ { "id": "A0A8V1AMR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1/entry#names_and_taxonomy" } ] }, { "name": "syntaxin-binding protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004946214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946214" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946214.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946214" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STXBP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1", "locus": { "chromosome": "18", "start_pos": 6524305, "end_pos": 6470448, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029241", "url": "https://www.ensembl.org/id/ENSGALG00010029241" } ] } } ], "crossref": [ { "id": "A0A8V1AMR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06692", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06692", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06698", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06698", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417393", "url": "https://www.ncbi.nlm.nih.gov/gene/417393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417393", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417393", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SWTHPVT", "url": "https://omabrowser.org/oma/group/SWTHPVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMR1", "url": "https://www.orthodb.org/?gene=A0A8V1AMR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946214", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLSPGDEDEPERFDGLSLLYWTIMGPHGINRAVHRISFSDCQNGLGVKIIGGYRAQTAEDYGIFIKRILPGGVAAVDSRLLAGDLILDVNGENLTGVTNERAVDILRTASASNHMSLLVARDEEAKKEFLDLMDKYGSHSDTYSARSSPTQPLAGKPVDSLSSGSSSRSQSPQLSPEDVTTTVSRKNSAPAASPKIAKDSAFQIISVCKGASLGLDIVGGIDRNEGPLVYIQEVIPGGDCHKDGRLQPGDQLVSINKESMIGVSYEEAKSIIDRARTRFESFCEIAFIRQKNVPSYSGNLQRPSSLIPPSAVVVGQQAAGPSPMASPNTKLVSALLPNAMETRVKMEEQSPITPAESSPADVSVHVIAPNQNDSYRLPGRKAVLNSTIRLKAEKLERALNYLGIQPSAEQQQALRQQLQKDSKGTVSFGDFVEVSRNLFSVHLDATDGGQKPVTFGIDEIVSLLDSQFVTWDSLEDDMEKLKKERNEALKEMSKLKEELSESLNLQKQLTEELQMVKQEAKAAVEETRALRSRIHLAEAAQRQARGMEMDYEEVIRLLEAEIVELKAQLSDHCGQNKDNIQDLRKRVTVLDCQLRKSESARKSFEVATEKLLQFVEVVHEMLSENSPSSAVLSDRRTPLSSKALLARLGRIGPTVTTALAAEARDLAKSVRAILEVNCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVTSALSLLCSEDDDDGIREPSGSKSH", "length": 736, "header": "tr|A0A8V1AMR1-1|A0A8V1AMR1_CHICK Isoform 1 of Syntaxin binding protein 4 OS=Gallus gallus OX=9031 GN=STXBP4 PE=4 SV=1 CANONICAL=A0A8V1AMR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1/entry#A0A8V1AGW6-1", "sequence": { "sequence": "MGTIMGPHGINRAVHRISFSDCQNGLGVKIIGGYRAQTAEDYGIFIKRILPGGVAAVDSRLLAGDLILDVNGENLTGVTNERAVDILRTASASNHMSLLVARDEEAKKEFLDLMDKYGSHSDTYSARSSPTQPLAGKPVDSLSSGSSSRSQSPQLSPEDVTTTVSRKNSAPAASPKIAKDSAFQIISVCKGASLGLDIVGGIDRNEGPLVYIQEVIPGGDCHKDGRLQPGDQLVSINKESMIGVSYEEAKSIIDRARTRFESFCEIAFIRQKNVPSYSGNLQRPSSLIPPSAVVVGQQAAGPSPMASPNTKLVSALLPNAMETRVKMEEQSPITPAESSPADVSVHVIAPNQNDSYRLPGRKAVLNSTIRLKAEKLERALNYLGIQPSAEQQQALRQQLQKDSKGTVSFGDFVEVSRNLFSVHLDATDGGQKPVTFGIDEIVSLLDSQFVTWDSLEDDMEKLKKERNEALKEMSKLKEELSESLNLQKQLTEELQMVKQEAKAAVEETRALRSRIHLAEAAQRQARGMEMDYEEVIRLLEAEIVELKAQLSDHCGQNKDNIQDLRKRVTVLDCQLRKSESARKSFEVATEKLLQFVEVVHEMLSENSPSSAVLSDRRTPLSSKALLARLGRIGPTVTTALAAEARDLAKSVRAILEVNCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVTSALSLLCSEDDDDGIREPSGSKSH", "length": 715, "header": "tr|A0A8V1AGW6-1|A0A8V1AMR1_CHICK Computationally mapped isoform of Syntaxin binding protein 4 OS=Gallus gallus OX=9031 GN=STXBP4 PE=4 SV=1 CANONICAL=A0A8V1AMR1-1" }, "locus": { "chromosome": "18", "start_pos": 6523324, "end_pos": 6471455, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070684.1", "url": "https://www.ensembl.org/id/ENSGALT00010070684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043375.1", "url": "https://www.ensembl.org/id/ENSGALP00010043375.1" } ] } }, { "isoform_ac": "A0A8V1AL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1/entry#A0A8V1AL33-1", "sequence": { "sequence": "MPETDLPTAPNGATIMGPHGINRAVHRISFSDCQNGLGVKIIGGYRAQTAEDYGIFIKRILPGGVAAVDSRLLAGDLILDVNGENLTGVTNERAVDILRTASASNHMSLLVARDEEAKKEFLDLMDKYGSHSDTYSARSSPTQPLAGKPVDSLSSGSSSRSQSPQLSPEDVTTTVSRKNSAPAASPKIAKDSAFQIISVCKGASLGLDIVGGIDRNEGPLVYIQEVIPGGDCHKDGRLQPGDQLVSINKESMIGVSYEEAKSIIDRARTRFESFCEIAFIRQKNVPSYSGNLQRPSSLIPPSAVVVGQQAAGPSPMASPNTKLVSALLPNAMETRVKMEEQSPITPAESSPADVSVHVIAPNQNDSYRLPGRKAVLNSTIRLKAEKLERALNYLGIQPSAEQQQALRQQLQKDSKGTVSFGDFVEVSRNLFSVHLDATDGGQKPVTFGIDEIVSLLDSQFVTWDSLEDDMEKLKKERNEALKEMSKLKEELSESLNLQKQLTEELQMVKQEAKAAVEETRALRSRIHLAEAAQRQARGMEMDYEEVIRLLEAEIVELKAQLSDHCGQNKDNIQDLRKRVTVLDCQLRKSESARKSFEVATEKLLQFVEVVHEMLSENSPSSAVLSDRRTPLSSKALLARLGRIGPTVTTALAAEARDLAKSVRAILEVNCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVTSALSLLCSEDDDDGIREPSGSKSH", "length": 726, "header": "tr|A0A8V1AL33-1|A0A8V1AMR1_CHICK Computationally mapped isoform of Syntaxin binding protein 4 OS=Gallus gallus OX=9031 GN=STXBP4 PE=4 SV=1 CANONICAL=A0A8V1AMR1-1" }, "locus": { "chromosome": "18", "start_pos": 6523324, "end_pos": 6471424, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070685.1", "url": "https://www.ensembl.org/id/ENSGALT00010070685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043376.1", "url": "https://www.ensembl.org/id/ENSGALP00010043376.1" } ] } }, { "isoform_ac": "A0A8V1AMR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1/entry#A0A8V1AMR1-1", "sequence": { "sequence": "MSLLSPGDEDEPERFDGLSLLYWTIMGPHGINRAVHRISFSDCQNGLGVKIIGGYRAQTAEDYGIFIKRILPGGVAAVDSRLLAGDLILDVNGENLTGVTNERAVDILRTASASNHMSLLVARDEEAKKEFLDLMDKYGSHSDTYSARSSPTQPLAGKPVDSLSSGSSSRSQSPQLSPEDVTTTVSRKNSAPAASPKIAKDSAFQIISVCKGASLGLDIVGGIDRNEGPLVYIQEVIPGGDCHKDGRLQPGDQLVSINKESMIGVSYEEAKSIIDRARTRFESFCEIAFIRQKNVPSYSGNLQRPSSLIPPSAVVVGQQAAGPSPMASPNTKLVSALLPNAMETRVKMEEQSPITPAESSPADVSVHVIAPNQNDSYRLPGRKAVLNSTIRLKAEKLERALNYLGIQPSAEQQQALRQQLQKDSKGTVSFGDFVEVSRNLFSVHLDATDGGQKPVTFGIDEIVSLLDSQFVTWDSLEDDMEKLKKERNEALKEMSKLKEELSESLNLQKQLTEELQMVKQEAKAAVEETRALRSRIHLAEAAQRQARGMEMDYEEVIRLLEAEIVELKAQLSDHCGQNKDNIQDLRKRVTVLDCQLRKSESARKSFEVATEKLLQFVEVVHEMLSENSPSSAVLSDRRTPLSSKALLARLGRIGPTVTTALAAEARDLAKSVRAILEVNCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVTSALSLLCSEDDDDGIREPSGSKSH", "length": 736, "header": "tr|A0A8V1AMR1-1|A0A8V1AMR1_CHICK Isoform 1 of Syntaxin binding protein 4 OS=Gallus gallus OX=9031 GN=STXBP4 PE=4 SV=1 CANONICAL=A0A8V1AMR1-1" }, "locus": { "chromosome": "18", "start_pos": 6523324, "end_pos": 6475409, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070683.1", "url": "https://www.ensembl.org/id/ENSGALT00010070683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043374.1", "url": "https://www.ensembl.org/id/ENSGALP00010043374.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 355, "start_aa": "Thr", "end_pos": 355, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr355", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 656, "start_aa": "Thr", "end_pos": 656, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr656", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417393", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B4S3-1", "protein_name": "Syntaxin-binding protein 4", "gene_name": "stxbp4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLPQSVEAEHFDGLSLLYWTIMGPHGINRAVERLEFTDCKKGLGVKIIGGYRGQSGEEFGIFIKRILPGGVAAQDGRLRPGDLILDVNNMNLRGVTNEKAVEVLRMASATNHMSLLVVRDDASRREFTELMEKYGSSSSTSSGSDTSVSTGKMTDTASSSSSSRSTSPLLLSPKEPSPVYTTACINSPSPQVCTDCMIQLICVAKGTGLGLVIRGGANRAEGPMVFVQEIIQGGDCQKDGRLKSGDQLISINKESLVGVTHEEAKSILTRTKLRPDPTVEIAFIRRRSSSGSSSGPHSPISLQPSCSTNHPAPQTKPSGLSGAALPGGLVPKIANTPNSGSETLPSVELTKVRAATGKPVLAPVTSPESACTTVANADASAACNPSRPSKPLCSVQSFELKPEKIDQTLEVLGLKPADSQVLTLRERLRLNAGGTVAYGDFDTVTKELFKQPSKLDSEQEVARLTSDDLIESPSNPTPSLSDSDDLDEMERLRKEHIEALRELKGLQDKLAESESLNHKMLQELTKVKQDAKSAVEESRSLRTRIHLAEAAQKQARGMEMDYEEVIHLLEAEIAEMKSLKTEQPSQEKEDLQDLKKRISVLECQLRKSEVAKKGFQVSTGKLLQFVEAVQSFLSENPSASRGHSSHYDVKSGTLSQTVASRGVKKTPCTASSLSVEAKELTQTVRSILELDCLPFGWDEAYTSDGVKYYINHVTQTTSWTHPVTRSLGLSDPGTSDHPTLDSPEFTA", "length": 749 }, "evidence": [ { "id": "A0A8V1AMR1", "url": "https://omabrowser.org/oma/group/A0A8V1AMR1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" }, { "name": "phagocytic vesicle", "id": "GO:0045335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" }, { "name": "regulation of insulin secretion involved in cellular response to glucose stimulus", "id": "GO:0061178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" }, { "name": "positive regulation of keratinocyte proliferation", "id": "GO:0010838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010838", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" }, { "name": "positive regulation of cell cycle G1/S phase transition", "id": "GO:1902808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 123, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AMR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR1" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 679, "end_pos": 712, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 355, 656 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 374, "end_pos": 376 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMW1-1", "uniprot_ac": "A0A8V1AMW1", "uniprot_id": "A0A8V1AMW1_CHICK", "mass": { "chemical_mass": 45143.0, "monoisotopic_mass": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CANT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1", "locus": { "chromosome": "18", "start_pos": 10394002, "end_pos": 10384465, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029266", "url": "https://www.ensembl.org/id/ENSGALG00010029266" } ] } } ], "crossref": [ { "id": "A0A8V1AMW1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMW1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR009283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13023:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13023:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "36799", "url": "https://www.rhea-db.org/rhea/36799", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCRLMPVPPCHESMSPLRISVGSLPVLASMTKGADPRFRLRWRAIVLSSACVGFVLLLFCLHRSPPARPIPPNPHGRHLRLQEEDRYNDTYPLSPPQRNPEGVRYRIGVIADLDTQSRGSEEHTWFSYLKKGYLVLSASGDSVTVEWDKEESVLQSHLAEKGRGMELSELVVFNGKLYSVDDRTGVVYQIEGNKAVPWVILSDGDGTVGKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVVNENPEWVKVVGYKGDVSHENWVVNYNALRAAAGIRPPGYLIHESASWSDTLQRWFFLPRRASHERYNEKADERRGTNLLLSSSQDFGDITVGRVGEVVPTHGFSSFKFIPDTDDQIIVALKSEEDDGKIASYIMAFTLDGRFLLPETWIGSVKYEGIEFI", "length": 402, "header": "tr|A0A8V1AMW1-1|A0A8V1AMW1_CHICK Isoform 1 of Soluble calcium-activated nucleotidase 1 OS=Gallus gallus OX=9031 GN=CANT1 PE=1 SV=1 CANONICAL=A0A8V1AMW1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1/entry#A0A8V1ABT5-1", "sequence": { "sequence": "MPVPPCHESMSPLRISVGSLPVLASMTKGADPRFRLRWRAIVLSSACVGFVLLLFCLHRSPPARPIPPNPHGRHLRLQEEDRYNDTYPLSPPQRNPEGVRYRIGVIADLDTQSRGSEEHTWFSYLKKGYLVLSASGDSVTVEWDKEESVLQSHLAEKGRGMELSELVVFNGKLYSVDDRTGVVYQIEGNKAVPWVILSDGDGTVGKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVVNENPEWVKVVGYKGDVSHENWVVNYNALRAAAGIRPPASFEARLVGVGVRGCPCSVAGSCMPYADRACSLLQVT", "length": 311, "header": "tr|A0A8V1ABT5-1|A0A8V1ABT5_CHICK Computationally mapped isoform of Calcium activated nucleotidase 1 OS=Gallus gallus OX=9031 GN=CANT1 PE=1 SV=1 CANONICAL=A0A8V1AMW1-1" }, "locus": { "chromosome": "18", "start_pos": 10392808, "end_pos": 10391422, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070767.1", "url": "https://www.ensembl.org/id/ENSGALT00010070767.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043458.1", "url": "https://www.ensembl.org/id/ENSGALP00010043458.1" } ] } }, { "isoform_ac": "A0A8V1AH39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1/entry#A0A8V1AH39-1", "sequence": { "sequence": "MMCRLSSPRRLMPVPPCHESMSPLRISVGSLPVLASMTKGADPRFRLRWRAIVLSSACVGFVLLLFCLHRSPPARPIPPNPHGRHLRLQEEDRYNDTYPLSPPQRNPEGVRYRIGVIADLDTQSRGSEEHTWFSYLKKGYLVLSASGDSVTVEWDKEESVLQSHLAEKGRGMELSELVVFNGKLYSVDDRTGVVYQIEGNKAVPWVILSDGDGTVGKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVVNENPEWVKVVGYKGDVSHENWVVNYNALRAAAGIRPPGMELPLVAACPLPCLGSPHSRWEQLLEGGTARAVSSSCVPWAKGAPALLWGVGRGRLRAGGSENTHSFGLHVSVLCCSIF", "length": 365, "header": "tr|A0A8V1AH39-1|A0A8V1AMW1_CHICK Computationally mapped isoform of Soluble calcium-activated nucleotidase 1 OS=Gallus gallus OX=9031 GN=CANT1 PE=1 SV=1 CANONICAL=A0A8V1AMW1-1" }, "locus": { "chromosome": "18", "start_pos": 10392705, "end_pos": 10385687, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070769.1", "url": "https://www.ensembl.org/id/ENSGALT00010070769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043460.1", "url": "https://www.ensembl.org/id/ENSGALP00010043460.1" } ] } }, { "isoform_ac": "A0A8V1AMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1/entry#A0A8V1AMW1-1", "sequence": { "sequence": "MMCRLMPVPPCHESMSPLRISVGSLPVLASMTKGADPRFRLRWRAIVLSSACVGFVLLLFCLHRSPPARPIPPNPHGRHLRLQEEDRYNDTYPLSPPQRNPEGVRYRIGVIADLDTQSRGSEEHTWFSYLKKGYLVLSASGDSVTVEWDKEESVLQSHLAEKGRGMELSELVVFNGKLYSVDDRTGVVYQIEGNKAVPWVILSDGDGTVGKGFKAEWLAVKDEHLYVGGLGKEWTTTTGEVVNENPEWVKVVGYKGDVSHENWVVNYNALRAAAGIRPPGYLIHESASWSDTLQRWFFLPRRASHERYNEKADERRGTNLLLSSSQDFGDITVGRVGEVVPTHGFSSFKFIPDTDDQIIVALKSEEDDGKIASYIMAFTLDGRFLLPETWIGSVKYEGIEFI", "length": 402, "header": "tr|A0A8V1AMW1-1|A0A8V1AMW1_CHICK Isoform 1 of Soluble calcium-activated nucleotidase 1 OS=Gallus gallus OX=9031 GN=CANT1 PE=1 SV=1 CANONICAL=A0A8V1AMW1-1" }, "locus": { "chromosome": "18", "start_pos": 10393170, "end_pos": 10385687, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070768.1", "url": "https://www.ensembl.org/id/ENSGALT00010070768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043459.1", "url": "https://www.ensembl.org/id/ENSGALP00010043459.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" }, { "name": "nucleoside diphosphate phosphatase activity", "id": "GO:0017110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" }, { "name": "GDP phosphatase activity", "id": "GO:0004382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" }, { "name": "ADP phosphatase activity", "id": "GO:0043262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" }, { "name": "UDP phosphatase activity", "id": "GO:0045134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36799", "name": "", "equation": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQY2-1", "A0A8V0ZNW3-1", "E1C1L6-1", "A0A8V1AMW1-1", "O93295-1", "P79784-1", "A0A1D5PS27-1", "A0A1D5PVS9-1", "A0A8V1AE46-1", "A0A8V1A8Y2-1" ], "evidence": [ { "id": "36799", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36799" } ] }, { "id": "R-GGA-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X7U8-1", "A0A8V0X868-1", "A0A8V0XIL3-1", "A0A8V1AIR0-1", "A2JDL7-1", "P08267-1", "A0A1D5PN36-1", "Q90629-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZN26-1", "A0A8V0ZPK4-1", "F1NN63-1", "A0A8V0YXL9-1", "A0A8V0ZNL2-1", "E1C9D9-1", "A0A8V0ZG12-1", "A0A3Q2UCN1-1", "P00698-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0Y248-1" ], "evidence": [ { "id": "R-GGA-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798745" } ] }, { "id": "R-GGA-6798749", "name": "Exocytosis of specific granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, specific granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XAC6-1", "A0A8V0XIL3-1", "A0A8V1AD74-1", "A0A8V1AMW1-1", "A0A8V0ZNL2-1", "Q8QFM7-1", "E1C9D9-1", "A0A8V0YW12-1", "A0A8V0ZJW2-1", "A0A3Q2UCN1-1", "P00698-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0Y248-1", "A0A8V0YBU4-1" ], "evidence": [ { "id": "R-GGA-6798749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798749" } ] }, { "id": "R-GGA-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PAA8-1", "A0A8V0X7U8-1", "A0A1D5PLH7-1", "A0A8V0XGV3-1", "A0A8V1AAF2-1", "A0A8V1ADZ5-1", "A0A8V1AIR0-1", "F1NI04-1", "A0A1D5PSE5-1", "A0A8V0XAS9-1", "O57535-1", "P08267-1", "Q90835-1", "A0A1L1RSD2-1", "R4GH41-1", "A0A8V0Y6Q3-1", "A0A8V1AMW1-1", "A0A8V0ZPK4-1", "A0A8V0ZQ64-1", "A0A8V0ZR27-1", "A0A8V0ZWJ4-1", "F1NN63-1", "A0A8V1A3K8-1", "A0A8V1A4Q4-1", "A0A8V0YHC8-1", "A0A8V0YXL9-1", "A0A8V0ZFP5-1", "A0A8V0ZG96-1", "A0A8V0ZTG8-1", "A0A8V0ZVL2-1", "A0A8V0Z0N7-1", "A0A8V0Z0Z6-1", "A0A8V0Z3A2-1", "F1NG97-1", "A0A8V0ZAK2-1", "A0A8V0ZG12-1", "A0A1D5PIQ5-1", "Q05744-1", "A0A8V0XX04-1", "A0A8V0XXA9-1", "A0A8V0YAA4-1", "A0A8V0Y4H1-1", "A0A8V0Y5M6-1", "A0A8V0YDR9-1", "A0A8V0YHT7-1" ], "evidence": [ { "id": "R-GGA-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6800434" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PAA8", "gene_name": "GYG1", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A1D5PAA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PAA8" } ] } ] }, { "uniprot_ac": "A0A1D5PIQ5", "gene_name": "MAPK14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A1D5PIQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PIQ5" } ] } ] }, { "uniprot_ac": "A0A1D5PLH7", "gene_name": "PRDX4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "A0A1D5PLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLH7" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A1D5PS27", "gene_name": "ENTPD2", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PS27" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A3Q2UCN1", "gene_name": "PTPN6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3Q2UCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCN1" } ] } ] }, { "uniprot_ac": "A0A8V0X7U8", "gene_name": "ALDOA", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "A0A8V0X7U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7U8" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XAC6", "gene_name": "HPSE", "activity": [ { "ec_number": "3.2.1.166", "activity": "endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan.", "evidence": [ { "id": "A0A8V0XAC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC6" } ] }, { "ec_number": "3.2.1.166", "activity": "", "evidence": [ { "id": "A0A8V0XAC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC6" } ] } ] }, { "uniprot_ac": "A0A8V0XAS9", "gene_name": "CAPN1", "activity": [ { "ec_number": "3.4.22.52", "activity": "Broad endopeptidase specificity.", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] }, { "ec_number": "3.4.22.52", "activity": "", "evidence": [ { "id": "A0A8V0XAS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAS9" } ] } ] }, { "uniprot_ac": "A0A8V0XGV3", "gene_name": "DDX3X", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XGV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGV3" } ] } ] }, { "uniprot_ac": "A0A8V0XIL3", "gene_name": "NIT2", "activity": [ { "ec_number": "3.5.1.3", "activity": "2-oxosuccinamate + H2O = oxaloacetate + NH4(+).", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] }, { "ec_number": "3.5.1.3", "activity": "", "evidence": [ { "id": "A0A8V0XIL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIL3" } ] } ] }, { "uniprot_ac": "A0A8V0XQY2", "gene_name": "", "activity": [ { "ec_number": "3.6.1.6", "activity": "a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQY2" } ] }, { "ec_number": "3.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0XQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQY2" } ] } ] }, { "uniprot_ac": "A0A8V0XX04", "gene_name": "QPCT", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "A0A8V0XX04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX04" } ] } ] }, { "uniprot_ac": "A0A8V0XXA9", "gene_name": "GPI", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXA9" } ] } ] }, { "uniprot_ac": "A0A8V0Y248", "gene_name": "QSOX1", "activity": [ { "ec_number": "1.8.3.2", "activity": "2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2.", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] }, { "ec_number": "1.8.3.2", "activity": "", "evidence": [ { "id": "A0A8V0Y248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y248" } ] } ] }, { "uniprot_ac": "A0A8V0Y4H1", "gene_name": "CTSB", "activity": [ { "ec_number": "3.4.22.1", "activity": "Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] }, { "ec_number": "3.4.22.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4H1" } ] } ] }, { "uniprot_ac": "A0A8V0Y5M6", "gene_name": "HK3", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "A0A8V0Y5M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5M6" } ] } ] }, { "uniprot_ac": "A0A8V0Y6Q3", "gene_name": "LTA4H", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y6Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6Q3" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YBU4", "gene_name": "PDXK", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "A0A8V0YBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBU4" } ] } ] }, { "uniprot_ac": "A0A8V0YDR9", "gene_name": "KCMF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YDR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR9" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YHT7", "gene_name": "DERA", "activity": [ { "ec_number": "4.1.2.4", "activity": "2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] }, { "ec_number": "4.1.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT7" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0YXL9", "gene_name": "MMP9", "activity": [ { "ec_number": "3.4.24.35", "activity": "Cleavage of gelatin types I and V and collagen types IV and V.", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] }, { "ec_number": "3.4.24.35", "activity": "", "evidence": [ { "id": "A0A8V0YXL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXL9" } ] } ] }, { "uniprot_ac": "A0A8V0Z0N7", "gene_name": "PPIA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0N7" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0Z3A2", "gene_name": "PPIE", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Z3A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A2" } ] } ] }, { "uniprot_ac": "A0A8V0ZAK2", "gene_name": "PYGL", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "A0A8V0ZAK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP5", "gene_name": "PGAM1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "A0A8V0ZFP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP5" } ] } ] }, { "uniprot_ac": "A0A8V0ZG12", "gene_name": "CDA", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "A0A8V0ZG12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG12" } ] } ] }, { "uniprot_ac": "A0A8V0ZG96", "gene_name": "PKLR", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A8V0ZG96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG96" } ] } ] }, { "uniprot_ac": "A0A8V0ZJW2", "gene_name": "RAB27A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZJW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0ZJW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW2" } ] } ] }, { "uniprot_ac": "A0A8V0ZN26", "gene_name": "LOC121106429", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] } ] }, { "uniprot_ac": "A0A8V0ZNL2", "gene_name": "C1R", "activity": [ { "ec_number": "3.4.21.41", "activity": "Selective cleavage of Lys(or Arg)-|-Ile bond in complement subcomponent C1s to form the active form of C1s (EC 3.4.21.42).", "evidence": [ { "id": "A0A8V0ZNL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL2" } ] }, { "ec_number": "3.4.21.41", "activity": "", "evidence": [ { "id": "A0A8V0ZNL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZNW3", "gene_name": "ENTPD1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ64", "gene_name": "AGL", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "2.4.1.25", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] }, { "ec_number": "3.2.1.33", "activity": "", "evidence": [ { "id": "A0A8V0ZQ64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ64" } ] } ] }, { "uniprot_ac": "A0A8V0ZR27", "gene_name": "PAFAH1B2", "activity": [ { "ec_number": "3.1.1.47", "activity": "a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+).", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] }, { "ec_number": "3.1.1.47", "activity": "", "evidence": [ { "id": "A0A8V0ZR27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR27" } ] } ] }, { "uniprot_ac": "A0A8V0ZTG8", "gene_name": "PFKL", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "A0A8V0ZTG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG8" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWJ4", "gene_name": "ALOX5", "activity": [ { "ec_number": "1.13.11.34", "activity": "(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O.", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] }, { "ec_number": "1.13.11.34", "activity": "", "evidence": [ { "id": "A0A8V0ZWJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ4" } ] } ] }, { "uniprot_ac": "A0A8V1A3K8", "gene_name": "APEH", "activity": [ { "ec_number": "3.4.19.1", "activity": "Internal cleavage of oxidized and glycated proteins.", "evidence": [ { "id": "A0A8V1A3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K8" } ] }, { "ec_number": "3.4.19.1", "activity": "", "evidence": [ { "id": "A0A8V1A3K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3K8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1AAF2", "gene_name": "MIF", "activity": [ { "ec_number": "5.3.2.1", "activity": "3-phenylpyruvate = enol-phenylpyruvate.", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF2" } ] }, { "ec_number": "5.3.3.12", "activity": "L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.", "evidence": [ { "id": "A0A8V1AAF2", "database": "UniProtKB", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH78", "url": "https://www.orthodb.org/?gene=A0A8V1AH78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALD4", "url": "https://www.orthodb.org/?gene=A0A8V1ALD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF653", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF653", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AH78", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGPAMPIVEKLREALKPGRREPSEDGELGRLLAASAKKVLLQRIEFEPASRGLSGQLELLRGKYRPLNASAGPAAPRPPPPEGPSRKHGGDHGAGDGVPAPQKVLFPAERLSLKWERVQRVGAGLHNLGNTCFLNATLQCLTYTPPLACYLLSKEHSRACHQGGFCMMCVMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYTIDAMQKACLSGCTRLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVSLEIRQAANIVRALELFVKSDVLSGENAYMCARCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKDVGYPEFLNIRPYMSQNSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHCSNIKVVLNQQAYVLFYLRIPGPRKGSEGPIAKATPSHSPVVSDQTKRTSTNGPLPSPLLGRSPEVLPGRKLSGPEEIGVPVARSTLGVGPKLPNGSAPPKPPTGSPSPKLPLRATQVTPSDDTARRPKKPPSPQRPPAPKASPGPYSSGTAHPPQQSPGDGTRSPTSPSPGTPQRGSCGSAAPSPAHTAAGDAAKAAPKAKSGAGGLSPPQDTDCGADLPEGSRLAKLKSAALEPGSTTSPPPAKKLALSAKKGSTPRRVSRSDGRVQPAGLAFPTATAQPWPCGRPRLPSALPLPSPDTPAFSFTPSAASQLPASPLTNGAHPSHHHPTLSGEHGPSPTSTKKKQRKQQQSKAGGSSHAMAVNGCDEGCSPPRKRRNIAPEGSIPGKEAAGTGREERDPRGSPSTEPISPLKKKKRKRRLQETEERSSGAQPLGSSRKADTEPSWTKQQQSPEPSEGESEHRKCKQRESLGNVTSEQPAAISAPAAACTWDSPARDGCKHRAAAPSSGAGTERSVVEELLRNSLDKAYGKQVLTWEGEVSAVSRDAVRDAEWARSETVIDEWDEEFDRGKVKKVKKLKRERRRHFNPFQQLQSKRNFWSVTHPAKVASLSYRL", "length": 1020, "header": "tr|A0A8V1ALD4-1|A0A8V1ALD4_CHICK Isoform 1 of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ALD4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4/entry#A0A8V1AH78-1", "sequence": { "sequence": 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"length": 1015, "header": "tr|A0A8V1AH78-1|A0A8V1ALD4_CHICK Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ALD4-1" }, "locus": { "chromosome": "18", "start_pos": 10411871, "end_pos": 10404858, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070809.1", "url": "https://www.ensembl.org/id/ENSGALT00010070809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043500.1", "url": "https://www.ensembl.org/id/ENSGALP00010043500.1" } ] } }, { "isoform_ac": "A0A8V1ALD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4/entry#A0A8V1ALD4-1", "sequence": { "sequence": "MPGPAMPIVEKLREALKPGRREPSEDGELGRLLAASAKKVLLQRIEFEPASRGLSGQLELLRGKYRPLNASAGPAAPRPPPPEGPSRKHGGDHGAGDGVPAPQKVLFPAERLSLKWERVQRVGAGLHNLGNTCFLNATLQCLTYTPPLACYLLSKEHSRACHQGGFCMMCVMQNHMIQAFANSGNAIKPVSFIRDLKKIARHFRFGSQEDAHEFLRYTIDAMQKACLSGCTRLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVSLEIRQAANIVRALELFVKSDVLSGENAYMCARCKKKVPASKRFTIHRASNVLTLSLKRFANFSGGKITKDVGYPEFLNIRPYMSQNSGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHCSNIKVVLNQQAYVLFYLRIPGPRKGSEGPIAKATPSHSPVVSDQTKRTSTNGPLPSPLLGRSPEVLPGRKLSGPEEIGVPVARSTLGVGPKLPNGSAPPKPPTGSPSPKLPLRATQVTPSDDTARRPKKPPSPQRPPAPKASPGPYSSGTAHPPQQSPGDGTRSPTSPSPGTPQRGSCGSAAPSPAHTAAGDAAKAAPKAKSGAGGLSPPQDTDCGADLPEGSRLAKLKSAALEPGSTTSPPPAKKLALSAKKGSTPRRVSRSDGRVQPAGLAFPTATAQPWPCGRPRLPSALPLPSPDTPAFSFTPSAASQLPASPLTNGAHPSHHHPTLSGEHGPSPTSTKKKQRKQQQSKAGGSSHAMAVNGCDEGCSPPRKRRNIAPEGSIPGKEAAGTGREERDPRGSPSTEPISPLKKKKRKRRLQETEERSSGAQPLGSSRKADTEPSWTKQQQSPEPSEGESEHRKCKQRESLGNVTSEQPAAISAPAAACTWDSPARDGCKHRAAAPSSGAGTERSVVEELLRNSLDKAYGKQVLTWEGEVSAVSRDAVRDAEWARSETVIDEWDEEFDRGKVKKVKKLKRERRRHFNPFQQLQSKRNFWSVTHPAKVASLSYRL", "length": 1020, "header": "tr|A0A8V1ALD4-1|A0A8V1ALD4_CHICK Isoform 1 of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ALD4-1" }, "locus": { "chromosome": "18", "start_pos": 10411871, "end_pos": 10404528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070810.1", "url": "https://www.ensembl.org/id/ENSGALT00010070810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043501.1", "url": "https://www.ensembl.org/id/ENSGALP00010043501.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "nucleolus organization", "id": "GO:0007000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007000", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "regulation of rRNA processing", "id": "GO:2000232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "negative regulation of macroautophagy", "id": "GO:0016242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "K48-linked deubiquitinase activity", "id": "GO:1990380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "histone H2B deubiquitinase activity", "id": "GO:0140936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" }, { "start_pos": 879, "end_pos": 881, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD4" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 425, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an 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"https://www.ncbi.nlm.nih.gov/protein/XP_040505446" }, "gene_names": [ { "name": "CYTH1", "type": "recommended", "evidence": [ { "id": "A0A8V1ALE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2" } ] }, { "name": "CYTH1", "type": "synonym", "evidence": [ { "id": "XP_040505446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505446" } ] }, { "name": "PSCD1", "type": "synonym", "evidence": [ { "id": "XP_040505446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505446" } ] }, { "name": "cytohesin-1", "type": "synonym", "evidence": [ { "id": "XP_040505446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505446" } ] } ], "protein_names": [ { "name": "Cytohesin 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ALE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2/entry#names_and_taxonomy" } ] }, { "name": "cytohesin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040505446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505446" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505446" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYTH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2", "locus": { "chromosome": "18", "start_pos": 10427454, "end_pos": 10412709, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029284", "url": "https://www.ensembl.org/id/ENSGALG00010029284" } ] } } ], "crossref": [ { "id": "A0A8V1ALE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01252", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01252", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422085", "url": "https://www.ncbi.nlm.nih.gov/gene/422085", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SCIMLNT", "url": "https://omabrowser.org/oma/group/SCIMLNT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AH87", "url": "https://www.orthodb.org/?gene=A0A8V1AH87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJA9", "url": "https://www.orthodb.org/?gene=A0A8V1AJA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALE2", "url": "https://www.orthodb.org/?gene=A0A8V1ALE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505446", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AH87", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AH87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTVSELCASSFQAFLCPSVAAAAVPSDLTPEECQELENIRRRKQELLADIQRLKDEIAEVTNEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTAERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 414, "header": "tr|A0A8V1ALE2-1|A0A8V1ALE2_CHICK Isoform 1 of Cytohesin 1 OS=Gallus gallus OX=9031 GN=CYTH1 PE=1 SV=1 CANONICAL=A0A8V1ALE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AH87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2/entry#A0A8V1AH87-1", "sequence": { "sequence": "MVLGVQGDVPSDLTPEECQELENIRRRKQELLADIQRLKDEIAEVTNEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTAERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 399, "header": "tr|A0A8V1AH87-1|A0A8V1ALE2_CHICK Computationally mapped isoform of Cytohesin 1 OS=Gallus gallus OX=9031 GN=CYTH1 PE=1 SV=1 CANONICAL=A0A8V1ALE2-1" }, "locus": { "chromosome": "18", "start_pos": 10426432, "end_pos": 10417311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070819.1", "url": "https://www.ensembl.org/id/ENSGALT00010070819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043510.1", "url": "https://www.ensembl.org/id/ENSGALP00010043510.1" } ] } }, { "isoform_ac": "A0A8V1AJA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2/entry#A0A8V1AJA9-1", "sequence": { "sequence": "MDEEGGYVPSDLTPEECQELENIRRRKQELLADIQRLKDEIAEVTNEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTAERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKMWPHASAPRAPRPSHSPAARTGLERRLDQY", "length": 402, "header": "tr|A0A8V1AJA9-1|A0A8V1ALE2_CHICK Computationally mapped isoform of Cytohesin 1 OS=Gallus gallus OX=9031 GN=CYTH1 PE=1 SV=1 CANONICAL=A0A8V1ALE2-1" }, "locus": { "chromosome": "18", "start_pos": 10427257, "end_pos": 10412731, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070821.1", "url": "https://www.ensembl.org/id/ENSGALT00010070821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043512.1", "url": "https://www.ensembl.org/id/ENSGALP00010043512.1" } ] } }, { "isoform_ac": "A0A8V1ALE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2/entry#A0A8V1ALE2-1", "sequence": { "sequence": "MGTVSELCASSFQAFLCPSVAAAAVPSDLTPEECQELENIRRRKQELLADIQRLKDEIAEVTNEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTAERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 414, "header": "tr|A0A8V1ALE2-1|A0A8V1ALE2_CHICK Isoform 1 of Cytohesin 1 OS=Gallus gallus OX=9031 GN=CYTH1 PE=1 SV=1 CANONICAL=A0A8V1ALE2-1" }, "locus": { "chromosome": "18", "start_pos": 10426432, "end_pos": 10415412, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070820.1", "url": "https://www.ensembl.org/id/ENSGALT00010070820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043511.1", "url": "https://www.ensembl.org/id/ENSGALP00010043511.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P97694-1", "protein_name": "Cytohesin-1", "gene_name": "Cyth1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 398 }, "evidence": [ { "id": "A0A8V1ALE2", "url": "https://omabrowser.org/oma/group/A0A8V1ALE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15438-1", "protein_name": "Cytohesin-1", "gene_name": "CYTH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAISRDPFYEMLAARKKKVSSTKRH", "length": 398 }, "evidence": [ { "id": "A0A8V1ALE2", "url": "https://omabrowser.org/oma/group/A0A8V1ALE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE2", "url": 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 367, "end_pos": 369 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALA2-1", "uniprot_ac": "A0A8V1ALA2", "uniprot_id": "A0A8V1ALA2_CHICK", "mass": { "chemical_mass": 39055.0, "monoisotopic_mass": 39055.0 }, "refseq": { "ac": "NP_990105", "name": "tropomodulin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" }, "gene_names": [ { "name": "TMOD4", "type": "recommended", "evidence": [ { "id": "A0A8V1ALA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ] }, { "name": "SK-TMOD", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] }, { "name": "TMOD4", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] }, { "name": "tropomodulin-4", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] } ], "protein_names": [ { "name": "Sk-tropomodulin", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] }, { "name": "Tropomodulin 4", "type": "synonym", "evidence": [ { "id": "A0A8V1ALA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2/entry#names_and_taxonomy" } ] }, { "name": "actin-capping protein", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] }, { "name": "skeletal muscle tropomodulin", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] }, { "name": "skeletal tropomodulin", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] }, { "name": "tropomodulin 4 (muscle)", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] }, { "name": "tropomodulin-4", "type": "synonym", "evidence": [ { "id": "NP_990105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01034023.1, AF165215.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992437, SAMN04013381 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000353.1. On Sep 23, 2021 this sequence version replaced NP_990105.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990105", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMOD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2", "locus": { "chromosome": "25", "start_pos": 2633998, "end_pos": 2638399, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028598", "url": "https://www.ensembl.org/id/ENSGALG00010028598" } ] } } ], "crossref": [ { "id": "A0A8V1ALA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "395547", "url": "https://www.ncbi.nlm.nih.gov/gene/395547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395547", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395547", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SDAEMCD", "url": "https://omabrowser.org/oma/group/SDAEMCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHA1", "url": "https://www.orthodb.org/?gene=A0A8V1AHA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJH6", "url": "https://www.orthodb.org/?gene=A0A8V1AJH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALA2", "url": "https://www.orthodb.org/?gene=A0A8V1ALA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990105", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990105", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSYRQELEKYRDIDEDKILQELSAEELEQLDTELLEMDPENVLLPAGLRQRDQTQKSPTGPLDREALLQHLEKQALEAKEREDLVPFTGEKKGKPFVPKNPTREIPREEQITLEPELEEALANATEAEMCDIAAILGMYTLMSNKQYYDAICSGTITNTEGINSVVKPDKYKPVPDEPPNPTNVEETLRQIQANDSALEDVNLNNIKDIPISTLKAICEAMKTNTHVKKLSLVATRSNDPVATAVAEMLAENKTLQSLNIESNFITSAGMMSVIKAMYQNSTLSELKVDNQCQRLGDTVEMEMATMLEQCPSVVRFGYHFTQQGPRARAAIAITRNNELRRKQKKT", "length": 347, "header": "tr|A0A8V1ALA2-1|A0A8V1ALA2_CHICK Isoform 1 of Tropomodulin 4 OS=Gallus gallus OX=9031 GN=TMOD4 PE=3 SV=1 CANONICAL=A0A8V1ALA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2/entry#A0A8V1AHA1-1", "sequence": { "sequence": "MTSYRQELEKYRDIDEDKILQELSAEELEQLDTELLEMDPENVLLPAGLRQRDQTQKSPTGPLDREALLQHLEKQALEAKEREDLVPFTGEKKGKPFVPKNPTREIPREEQITLEPELEEALANATEAEMCDIAAILGMYTLMSNKQYYDAICSGTITNTEGINSVVKPDKYKPVPDEPPNPTNVEETLRQIQANDSALEDVNLNNIKDIPISTLKAICEAMKTNTHVKKLSLVATRSNDPVATAVAEMLAENKTLQSLNIESNFITSAGMMSVIKAMYQNSTLSELKVDNQCQRLGDTVEMEMATMLEQCPSVVRFGYHFTQQGPRARAAIAITRNNELRECPQGGNGAKSGA", "length": 354, "header": "tr|A0A8V1AHA1-1|A0A8V1ALA2_CHICK Computationally mapped isoform of Tropomodulin 4 OS=Gallus gallus OX=9031 GN=TMOD4 PE=3 SV=1 CANONICAL=A0A8V1ALA2-1" }, "locus": { "chromosome": "25", "start_pos": 2637789, "end_pos": 2635002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069259.1", "url": "https://www.ensembl.org/id/ENSGALT00010069259.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042701.1", "url": "https://www.ensembl.org/id/ENSGALP00010042701.1" } ] } }, { "isoform_ac": "A0A8V1AJH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2/entry#A0A8V1AJH6-1", "sequence": { "sequence": "MTSYRQELEKYRDIDEDKILQELSAEELEQLDTELLEMDPENVLLPAGLRQRDQTQKSPTGPLDREALLQHLEKQALEAKEREDLVPFTGEKKGKPFVPKNPTREIPREEQITLEPELEEALANATEAEMCDIAAILGMYTLMSNKQYYDAICSGTITNTEGINSVVKPDKYKPVPDEPPNPTNVEETLRQIQANDSALEDVNLNNIKDIPISTLKAICEAMKTNTHVKKLSLVATRSNDPVATAVAEMLAENKTLQSLNIESNFITSAGMMSVIKAMYQNSTLSELKVDNQVGMGNHRDQEGSGGGGGQDGGSHFAPRHHCLQCQRLGDTVEMEMATMLEQCPSVVRFGYHFTQQGPRARAAIAITRNNELRECPQGGNGAKSGA", "length": 386, "header": "tr|A0A8V1AJH6-1|A0A8V1ALA2_CHICK Computationally mapped isoform of Tropomodulin 4 OS=Gallus gallus OX=9031 GN=TMOD4 PE=3 SV=1 CANONICAL=A0A8V1ALA2-1" }, "locus": { "chromosome": "25", "start_pos": 2637789, "end_pos": 2635002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069258.1", "url": "https://www.ensembl.org/id/ENSGALT00010069258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042700.1", "url": "https://www.ensembl.org/id/ENSGALP00010042700.1" } ] } }, { "isoform_ac": "A0A8V1ALA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2/entry#A0A8V1ALA2-1", "sequence": { "sequence": "MTSYRQELEKYRDIDEDKILQELSAEELEQLDTELLEMDPENVLLPAGLRQRDQTQKSPTGPLDREALLQHLEKQALEAKEREDLVPFTGEKKGKPFVPKNPTREIPREEQITLEPELEEALANATEAEMCDIAAILGMYTLMSNKQYYDAICSGTITNTEGINSVVKPDKYKPVPDEPPNPTNVEETLRQIQANDSALEDVNLNNIKDIPISTLKAICEAMKTNTHVKKLSLVATRSNDPVATAVAEMLAENKTLQSLNIESNFITSAGMMSVIKAMYQNSTLSELKVDNQCQRLGDTVEMEMATMLEQCPSVVRFGYHFTQQGPRARAAIAITRNNELRRKQKKT", "length": 347, "header": "tr|A0A8V1ALA2-1|A0A8V1ALA2_CHICK Isoform 1 of Tropomodulin 4 OS=Gallus gallus OX=9031 GN=TMOD4 PE=3 SV=1 CANONICAL=A0A8V1ALA2-1" }, "locus": { "chromosome": "25", "start_pos": 2637789, "end_pos": 2634940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069256.1", "url": "https://www.ensembl.org/id/ENSGALT00010069256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042698.1", "url": "https://www.ensembl.org/id/ENSGALP00010042698.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395547", "resource": "KEGG Pathway" }, { "id": "R-GGA-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZL64-1", "protein_name": "Tropomodulin 4", "gene_name": "TMOD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSYLKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREIPKEEQITLEPELEEALAHATDAEMCDIAAILGMYTLMSNKQYYDALCSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEILKSVRSNDKELEEVNLNNIQDIPIPMLTELCEAMKTNTHVRSFSLVATRSGDPIAHAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQKKR", "length": 345 }, "evidence": [ { "id": "A0A8V1ALA2", "url": "https://omabrowser.org/oma/group/A0A8V1ALA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZSG3-1", "protein_name": "Tropomodulin 4", "gene_name": "Tmod4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPFTGEKKGKPFIQPKREIPAQEQITLEPELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLLSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAANAMTRNNELRRQQKKR", "length": 345 }, "evidence": [ { "id": "A0A8V1ALA2", "url": "https://omabrowser.org/oma/group/A0A8V1ALA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VC48-1", "protein_name": "Tropomodulin-4", "gene_name": "TMOD4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSYQKELEKYRDIDEDEILKTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREIPVEEQVTLEPELEEALAHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEILKSVRSNDKEVEEVNLNNIQDIPIPMLTELCEAMKTNTHVRSFSLVATRSGDPVANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQKKR", "length": 345 }, "evidence": [ { "id": "A0A8V1ALA2", "url": "https://omabrowser.org/oma/group/A0A8V1ALA2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9JLH8-1", "protein_name": "Tropomodulin-4", "gene_name": "Tmod4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDRDALLQYLEQQALEVKERDDLVPYTGEKKGKPFIQPKREIPAQEQITLEPELEEALSHATDAEMCDIAAILGMYTLMSNKQYYDAICSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEMLKRVRSNDKELEEVNLNNIQDIPIPVLSDLCEAMKTNTYVRSFSLVATKSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAHAMTRNNELRRQQKKR", "length": 345 }, "evidence": [ { "id": "A0A8V1ALA2", "url": "https://omabrowser.org/oma/group/A0A8V1ALA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZQ9-1", "protein_name": "Tropomodulin-4", "gene_name": "TMOD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGPLDREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREIPAEEQITLEPELEEALAHATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEGISSVVQPDKYKPVPDEPPNPTNIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIANAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEMEMATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQKKR", "length": 345 }, "evidence": [ { "id": "A0A8V1ALA2", "url": "https://omabrowser.org/oma/group/A0A8V1ALA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" }, { "name": "tropomyosin binding", "id": "GO:0005523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" }, { "name": "striated muscle thin filament", "id": "GO:0005865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "pointed-end actin filament capping", "id": "GO:0051694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" }, { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" }, { "name": "myofibril assembly", "id": "GO:0030239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030239", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALB3-1", "uniprot_ac": "A0A8V1ALB3", "uniprot_id": "A0A8V1ALB3_CHICK", "mass": { "chemical_mass": 136222.0, "monoisotopic_mass": 136222.0 }, "refseq": { "ac": "XP_427387", "name": "zinc finger protein 687 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427387" }, "gene_names": [ { "name": "ZNF687", "type": "recommended", "evidence": [ { "id": "A0A8V1ALB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" } ] }, { "name": "ZNF687", "type": "synonym", "evidence": [ { "id": "XP_427387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427387" } ] } ], "protein_names": [ { "name": "Zinc finger protein 687", "type": "synonym", "evidence": [ { "id": "A0A8V1ALB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 687 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_427387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427387" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_427387.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_427387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427387" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AHA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA6#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3#function" }, { "database": "UniProtKB", "id": "A0A8V1A9R7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF687", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3", "locus": { "chromosome": "25", "start_pos": 2675473, "end_pos": 2664455, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028602", "url": "https://www.ensembl.org/id/ENSGALG00010028602" } ] } } ], "crossref": [ { "id": "A0A8V1ALB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "429831", "url": "https://www.ncbi.nlm.nih.gov/gene/429831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429831", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKVPSCQ", "url": "https://omabrowser.org/oma/group/PKVPSCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9R7", "url": "https://www.orthodb.org/?gene=A0A8V1A9R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHA6", "url": "https://www.orthodb.org/?gene=A0A8V1AHA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALB3", "url": "https://www.orthodb.org/?gene=A0A8V1ALB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47222:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47222:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_427387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_427387", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A9R7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDTNEAIHSGHDEAEAHIKPVPGEPGPPDHVLPHTDITAVSVIVKNTVCPEQLDALDGRSKDGHGLGSRLLQNGFGAAELPRSPAARSVEAVASSNGECWVKEKGPKPLDIFSHFSPDPNEDSAANLIDRARECKPKEKSLAVPSLSPSPTPSLDCKEPGGEGAEGLPPPFPQPFEGSQAGAVSGPPPSVPCIKKEESDSEEAAREANPKALSAALGENPLEHLKSVTVRYSAGDSPITSWPGSDPSLGSGASSLPEVKHSPSSPREPFFKPSSPVVQSPRIPTSPKQLDDITLKEEREALEKSMGSPQSMSSAEEEEEEEEGNTNDSPSSNSSRPLKVRIKTIKTSCGSITRTVTRVSSDSEPGSARGSAEQSSEDAALEAEKEDGVALEVPREKLDLSSPLKAIEGPKIVSVQLGNGTKIKGTVLPVSTIQNASSAMLIAASVAQQKSVVLPAKTGKAVTKNIINLVPQALPKADTRTNASPVTQTTSVTTTANQKLNGTTVVMVQPQKPSPTVAGTVISRSQSSLVEAFNKILNSKNLLPTYKPNLSPPADASLALPPFGYRCLECGDSFALEKSLARHYDRRSMRIEVTCNHCTKRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPIALDQMIGQPDITPLVSVASFPAGKVAGVTQDALSAANGAPELPILPLSSSGSEQSNYSCFRCLECKEQCKDKAGLAAHFQQAVATGTTSSTVCTTCPMIMSNRCSFSAHQRMHKNRPPHVCPECGGNFLLANFETHLKESCLHFSRRVGYRCPSCAVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSAPSAHAHVYTQHPGFGNQQSKMIYKCAMCDTVFTHKPLLSSHFDQHLLNQRVSVFKCPDCPLLFAQKRTMLEHLKNTHQPPKPREEPTKKAAVLLTPKQEPMETPVPKISDESSSSTEEDDPPSSPELRKAKRSRFQRKATSKPKGSGWTCGVCHSWFPERDEYVSHMKKDHGKSVKKFPCHLCERSFCSAPSLRRHVRVNHEGIKRVYPCRFCTEGKRTFSSRLILEKHIQVRHGIKVTDQTKSQEVIIARIGAGAVQVPGRKRKLSSDDGDSCSEEPDSTTPPSKNPKGDRKAPFRCRKCGYVASSAADFQEHIPQHRTDESSHQCRECGLCFTSQVSLNRHRFITHKKKKGAGEAEEPGPRSPLEGAPHAADGALSCTVCGRSFDSQLNLKTHFRTHGMAFIRARQNVSPEN", "length": 1257, "header": "tr|A0A8V1ALB3-1|A0A8V1ALB3_CHICK Isoform 1 of Zinc finger protein 687 OS=Gallus gallus OX=9031 GN=ZNF687 PE=1 SV=1 CANONICAL=A0A8V1ALB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3/entry#A0A8V1A9R7-1", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDTNEAIHSGHDEAEAHIKPVPGEPGPPDHVLPHTDITAVSVIVKNTVCPEQLDALDGRSKDGHGLGSRLLQNGFGAAELPRSPAASPDPNEDSAANLIDRARECKPKEKSLAVPSLSPSPTPSLDCKEPGGEGAEGLPPPFPQPFEGSQAGAVSGPPPSVPCIKKEESDSEEAAREANPKALSAALGENPLEHLKSVTVRYSAGDSPITSWPGSDPSLGSGASSLPEVKHSPSSPREPFFKPSSPVVQSPRIPTSPKQLDDITLKEEREALEKSMGSPQSMSSAEEEEEEEEGNTNDSPSSNSSRPLKVRIKTIKTSCGSITRTVTRVSSDSEPGSARGSAEQSSEDAALEAEKEDGVALEVPREKLDLSSPLKAIEGPKIVSVQLGNGTKIKGTVLPVSTIQNASSAMLIAASVAQQKSVVLPAKTGKAVTKNIINLVPQALPKADTRTNASPVTQTTSVTTTANQKLNGTTVVMVQPQKPSPTVAGTVISRSQSSLVEAFNKILNSKNLLPTYKPNLSPPADASLALPPFGYRCLECGDSFALEKSLARHYDRRSMRIEVTCNHCTKRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPIALDQMIGQPDITPLVSVASFPAGKVAGVTQDALSAANGAPELPILPLSSSGSEQSNYSCFRCLECKEQCKDKAGLAAHFQQAVATGTTSSTVCTTCPMIMSNRCSFSAHQRMHKNRPPHVCPECGGNFLLANFETHLKESCLHFSRRVGYRCPSCAVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSAPSAHAHVYTQHPGFGNQQSKMIYKCAMCDTVFTHKPLLSSHFDQHLLNQRVSVFKCPDCPLLFAQKRTMLEHLKNTHQPPKPREEPTKKAAVLLTPKQEPMETPVPKISDESSSSTEEDDPPSSPELRKAKRSRFQRKATSKPKGSGWTCGVCHSWFPERDEYVSHMKKDHGKSVKKFPCHLCERSFCSAPSLRRHVRVNHEGIKRVYPCRFCTEGKRTFSSRLILEKHIQVRHGIKVTDQTKSQEVIIARIGAGAVQVPGRKRKLSSDDGDSCSEEPDSTTPPSKNPKGDRKAPFRCRKCGYVASSAADFQEHIPQHRTDESSHQCRECGLCFTSQVSLNRHRFITHKKKKGAGEAEEPGPRSPLEGAPHAADGALSCTVCGRSFDSQLNLKTHFRTHGMAFIRARQNVSPEN", "length": 1228, "header": "tr|A0A8V1A9R7-1|A0A8V1A9R7_CHICK Computationally mapped isoform of Zinc finger protein 687 OS=Gallus gallus OX=9031 GN=ZNF687 PE=1 SV=1 CANONICAL=A0A8V1ALB3-1" }, "locus": { "chromosome": "25", "start_pos": 2674469, "end_pos": 2668294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069265.1", "url": "https://www.ensembl.org/id/ENSGALT00010069265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042707.1", "url": "https://www.ensembl.org/id/ENSGALP00010042707.1" } ] } }, { "isoform_ac": "A0A8V1AHA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3/entry#A0A8V1AHA6-1", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDTNEAIHSGHDEAEAHIKPVPGEPGPPDHVLPHTDITAVSVIVKNTVCPEQLDALDGRSKDGHGLGSRLLQNGFGAAELPRSPAARSVEAVASSNGECWVKEKGPKPLDIFSHFSPDPNEDSAANLIDRARECKPKEKSLAVPSLSPSPTPSLDCKEPGGEGAEGLPPPFPQPFEGSQAGAVSGPPPSVPCIKKEESDSEEAAREANPKALSAALGENPLEHLKSVTVRYSAGDSPITSWPGSDPSLGSGASSLPEVKHSPSSPREPFFKPSSPVVQSPRIPTSPKQLDDITLKEEREALEKSMGSPQSMSSAEEEEEEEEGNTNDSPSSNSSRPLKVRIKTIKTSCGSITRTVTRVSSDSEPGSARGSAEQSSEDAALEAEKEDGVALEVPREKLDLSSPLKAIEGPKIVSVQLGNGTKIKGTVLPVSTIQNASSAMLIAASVAQQKSVVLPAKTGKAVTKNIINLVPQALPKADTRTNASPVTQTTSVTTTANQKLNGTTVVMVQPQKPSPTVAGTVISRSQSSLVEAFNKILNSKNLLPTYKPNLSPPADASLALPPFGYRCLECGDSFALEKSLARHYDRRSMRIEVTCNHCTKRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPIALDQMIGQPDITPLVSVASFPAGKVAGVTQDALSAANGAPELPILPLSSSGSEQSNYSCFRCLECKEQCKDKAGLAAHFQQAVATGTTSSTVCTTCPMIMSNRCSFSAHQRMHKNRPPHVCPECGGNFLLANFETHLKESCLHFSRRVGYRMIYKCAMCDTVFTHKPLLSSHFDQHLLNQRVSVFKCPDCPLLFAQKRTMLEHLKNTHQPPKPREEPTKKAAVLLTPKQEPMETPVPKISDESSSSTEEDDPPSSPELRKAKRSRFQRKATSKPKGSGWTCGVCHSWFPERDEYVSHMKKDHGKSVKKFPCHLCERSFCSAPSLRRHVRVNHEGIKRVYPCRFCTEGKRTFSSRLILEKHIQVRHGIKVTDQTKSQEVIIARIGAGAVQVPGRKRKLSSDDGDSCSEEPDSTTPPSKNPKGDRKAPFRCRKCGYVASSAADFQEHIPQHRTDESSHQCRECGLCFTSQVSLNRHRFITHKKKKGAGEAEEPGPRSPLEGAPHAADGALSCTVCGRSFDSQLNLKTHFRTHGMAFIRARQNVSPEN", "length": 1198, "header": "tr|A0A8V1AHA6-1|A0A8V1ALB3_CHICK Computationally mapped isoform of Zinc finger protein 687 OS=Gallus gallus OX=9031 GN=ZNF687 PE=1 SV=1 CANONICAL=A0A8V1ALB3-1" }, "locus": { "chromosome": "25", "start_pos": 2674469, "end_pos": 2668294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069264.1", "url": "https://www.ensembl.org/id/ENSGALT00010069264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042706.1", "url": "https://www.ensembl.org/id/ENSGALP00010042706.1" } ] } }, { "isoform_ac": "A0A8V1ALB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3/entry#A0A8V1ALB3-1", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDTNEAIHSGHDEAEAHIKPVPGEPGPPDHVLPHTDITAVSVIVKNTVCPEQLDALDGRSKDGHGLGSRLLQNGFGAAELPRSPAARSVEAVASSNGECWVKEKGPKPLDIFSHFSPDPNEDSAANLIDRARECKPKEKSLAVPSLSPSPTPSLDCKEPGGEGAEGLPPPFPQPFEGSQAGAVSGPPPSVPCIKKEESDSEEAAREANPKALSAALGENPLEHLKSVTVRYSAGDSPITSWPGSDPSLGSGASSLPEVKHSPSSPREPFFKPSSPVVQSPRIPTSPKQLDDITLKEEREALEKSMGSPQSMSSAEEEEEEEEGNTNDSPSSNSSRPLKVRIKTIKTSCGSITRTVTRVSSDSEPGSARGSAEQSSEDAALEAEKEDGVALEVPREKLDLSSPLKAIEGPKIVSVQLGNGTKIKGTVLPVSTIQNASSAMLIAASVAQQKSVVLPAKTGKAVTKNIINLVPQALPKADTRTNASPVTQTTSVTTTANQKLNGTTVVMVQPQKPSPTVAGTVISRSQSSLVEAFNKILNSKNLLPTYKPNLSPPADASLALPPFGYRCLECGDSFALEKSLARHYDRRSMRIEVTCNHCTKRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPIALDQMIGQPDITPLVSVASFPAGKVAGVTQDALSAANGAPELPILPLSSSGSEQSNYSCFRCLECKEQCKDKAGLAAHFQQAVATGTTSSTVCTTCPMIMSNRCSFSAHQRMHKNRPPHVCPECGGNFLLANFETHLKESCLHFSRRVGYRCPSCAVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSAPSAHAHVYTQHPGFGNQQSKMIYKCAMCDTVFTHKPLLSSHFDQHLLNQRVSVFKCPDCPLLFAQKRTMLEHLKNTHQPPKPREEPTKKAAVLLTPKQEPMETPVPKISDESSSSTEEDDPPSSPELRKAKRSRFQRKATSKPKGSGWTCGVCHSWFPERDEYVSHMKKDHGKSVKKFPCHLCERSFCSAPSLRRHVRVNHEGIKRVYPCRFCTEGKRTFSSRLILEKHIQVRHGIKVTDQTKSQEVIIARIGAGAVQVPGRKRKLSSDDGDSCSEEPDSTTPPSKNPKGDRKAPFRCRKCGYVASSAADFQEHIPQHRTDESSHQCRECGLCFTSQVSLNRHRFITHKKKKGAGEAEEPGPRSPLEGAPHAADGALSCTVCGRSFDSQLNLKTHFRTHGMAFIRARQNVSPEN", "length": 1257, "header": "tr|A0A8V1ALB3-1|A0A8V1ALB3_CHICK Isoform 1 of Zinc finger protein 687 OS=Gallus gallus OX=9031 GN=ZNF687 PE=1 SV=1 CANONICAL=A0A8V1ALB3-1" }, "locus": { "chromosome": "25", "start_pos": 2674469, "end_pos": 2668294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069266.1", "url": "https://www.ensembl.org/id/ENSGALT00010069266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042708.1", "url": "https://www.ensembl.org/id/ENSGALP00010042708.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 535, "start_aa": "Thr", "end_pos": 535, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr535", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:429831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429831", "resource": "KEGG Pathway" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SCI8-1", "protein_name": "Zinc finger protein 687", "gene_name": "ZNF687", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGSGKPEPSVGGESGEATAAPAGDGPGGPTQASDHSLPPPDVSAVSVIVKNTVCPEQSESLAGSSGGEGARAGGVTKEGPLGPRLMQNGFGGPEPSLPGTPRSPAPPSGGTWKEKSLEGKAPLDLFAHFGPEPGEHPDPLPPSAPSPPREGALTPPAFPSPFELTRENGPALLPPSSPPLLGTLKQESCSPLHPQSLAQPGSGTSPEATGVPASASPSQVAGVSFFKKSPGHQSPLASPKGPSCQPLKEEEDEGPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTRVPSDPDPPAPLAEGGFLAEANLLKLSPATPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGTATSPKTMPKNVLGLVPQALPKAEGRTGLGTGGQKVNGASVVMVQPSKPATGPGAAGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLAVPPALGPPALPALGKGEGAVTTSAITAVAAEAPVLPLSTEPPATPATSTYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSAPSAHAHLYTQHPSFHTQQAKMIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRPGEETAGKGAGGALLTPKTEPEELAVSRAGTAAPTEESSSTSEEEEPPSSPEPPRPTKRPRRELGSKGMKGGGGGPGGWTCGLCHSWFPERDEYVGHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGAQSPGRGSALARGPGARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGAPGSGGHGPLRYRGGGSAEQSLMVGLRVDGGAQQCLDCGLCFASPGSLSRHRFISHKKKRGVGSASALGLGDGEEEAPPPSRSDPDGGESPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN", "length": 1236 }, "evidence": [ { "id": "A0A8V1ALB3", "url": "https://omabrowser.org/oma/group/A0A8V1ALB3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZT56-1", "protein_name": "Zinc finger protein 687", "gene_name": "Zfp687", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGLLANGEYESGQLGLGARRELRERGGRSGEKQEVAAAAGRAAAAAAAVAAGTGGGRRVSARTRIGTSLGPVTMGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGQGKPESSVGGDSKDREAATATENDPESAAEASDHGLPQPPDTSTVSVIVKNTVCPEQSETLTGNSEEETKAGDVTKEGPVGSCLMQNGFGGPEPSLSETPHSSAPASGDAWEEKAGEGKTCLDLFAHFGSEPGDHTDPLPPEPSLPRDGDMAPPPFSTPFELAPENGSTLLPPTSLLPQGALKQESCSPHHSQGLTQRNSGSSPEAAGVPASVSPPQVAGVSFKQSPGHQSPPASPVKAPSCKPLKEEDEGTVDKSPPRSPQSPSSGAEAADEDSNDSPTSSSSSRPLKVRIKTIKTSCGNITRTVTRVPSEPDPPAPLAEGAFLAEASFLKLSPVTPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGNATSPKTMTKNVLGLVPQTLPKAEVRTGFTLGGQKVNGASVVMVQPSKSATGPGTAGGSVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVPGPLALPVLGKGEGAVTSSTITTVATEAPVLPLPTEPPAPPAASVYTCFRCLECKEQCRDKAGMAAHFQQLGPPALGSTSNVCPSCPMMLPNRCSFSAHQRTHKNRPPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGVNSIKSHIQASHCEVFHKCPICPMAFKSAPSAHAHLYSQHPSFLTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRVGEEAAGKGAGGALLTPKTEPEELAVSQAEAAPATEESSSTSEEELPSSPDPPRPAKRARRELGNKGIKGGGGGPGGWTCGVCHSWCPERDEYVTHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGTQSSGRGGSLVRGSGGRAQGPGRKRRQSSDSCSEEPDSTTPPAKSLRGGPGSGGHGPLRYRSSGSAEQSLVGLRVDGGTQQCLDCGLCFASPGSLSRHRFISHKKRRAGGKASVLGLGDGEEEAPPLRSDPEGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN", "length": 1309 }, "evidence": [ { "id": "A0A8V1ALB3", "url": "https://omabrowser.org/oma/group/A0A8V1ALB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H2Z9-1", "protein_name": "Zinc finger protein 687", "gene_name": "Znf687", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGQGKPEPSEGGDSGDRAATATTEDDPESPAEASEHGLLQPPDTSTVSVIVKNTVCPEQSETLTENSGEEETKAGGVTKGGPVGSCLMQNGFGGPEPPLSETPHSPAPANGDAWKEKAMEGKTPLDLFAHFGSEPGDHPDPLPPEPSPSQDGDMIPPPFSTPFELAPENGSTLLPPGSLLPEGALKQENCSPPHSQGLTQRSSGSSPEAAGIPASASPPQVAGMSFKQSPGHQSPPASPEKASSCKPLKEEDEGTVDKSPPRSPQSPSSGAEAADEDSNDSPTSSSSARPLKVRIKTIKTSCGNITRTVTRVPSEPDPPAPLPEGAFLAEASFLKLSPVTPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGNVTSPKTMTKSVLGLVPQTLPKAEVRTTLGLGGQKVNGASVVMVQPSKSATGPGTAGGSVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVPGPLALPVLGKGEGAVTSSTITTVATEAPVLPLPTEPPALPTASVYTCFRCLECKEQCRDKAGMAAHFQQLGPPALGSTSNMCPSCPMMLPNRCSFSAHQRTHKNRPPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGINSIKSHIQASHCEVFHKCPICPMAFKSAPSAHAHLYSQHPSFLTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKSTHQSGRLGEEAVGKGAGGALLTPKTEPEELAVSRAEAAPATEESSSSSEEELPSSPEPPRPTKRPRRDLGSKGIKGGGGGPGGWTCGLCHSWFPERDDYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGTQSPSGRGGTLVRGSGGRAQGPGRKRRQSSDSCSEEPDSTTPPAKSLRGGPGSGGHGPLRYRSSGSVEQSIVVGLRVDGGTQQCLDCGLCFASPGSLSRHRFISHKKRRAGGKASALGMADGEEEAPPLRSDPEGGDSPLPVSGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN", "length": 1238 }, "evidence": [ { "id": "A0A8V1ALB3", "url": "https://omabrowser.org/oma/group/A0A8V1ALB3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8N1G0-1", "protein_name": "Zinc finger protein 687", "gene_name": "ZNF687", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPSAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN", "length": 1237 }, "evidence": [ { "id": "A0A8V1ALB3", "url": "https://omabrowser.org/oma/group/A0A8V1ALB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2D7-1", "protein_name": "Zinc finger protein 687", "gene_name": "Znf687", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGQGKPEPSVGGDSKDREEAAAAENDPESPAEASDHGLPQPPDTSTVSVIVKNTVCPEQSESLTGDSGEEETKAGGITKEGPVGSCLMQNGFGGPEPSLSENPHSSAHASGNAWKDKAVEGKTCLDLFAHFGSEPGDHPDPLPPEPSQPRGGDMAPPPFSTPFELAPENGSTLLPPASLLPQGALKQESCSPHHSQGLTQRGPGSSPETAGIPASVSPPQVAGVSFKQSPGHQSPPASPVKAPSCKPLKEEDEGTVDKSPPRSPQSPSSGAEAADEDSNDSPTSSSSSRPLKVRIKTIKTSCGNITRTVTRVPSEPDPPAPLAEGAFLAETSFLKLSPVTPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGNATSPKTMTKSVLGLVPQTLPKAEVRTGFSLGGQKVNGASVVMVQPSKSATGPGTAGGSVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVPGPLALPVLGKGEGAVTSSTITTVATEAPVLPLPTEPPAPPTASVYTCFRCLECKEQCRDKAGMAAHFQQLGPPALGSTSNVCPSCPMMLPNRCSFSAHQRTHKNRAPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGVNSIKSHIQASHCEVFHKCPICPMAFKSAPSAHAHLYSQHPSFLTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRVGEEAVGKGAGGALLTPKTEPEELAVSQAEAAPATEESSSSSEEELPSSPEPPRPTKRARRGELGNKGIKGGGGGPGGWTCGLCHSWCPERDEYVTHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGTQSSGRGGSLARGSGGRAQGPGRKRRQSSDSCSEEPDSTTPPAKSLRGGPGSGGHGPLRYRSSGSAEQSLVGLRVDGGTQQCLDCGLCFASPGSLSRHRFISHKKRRAGGKASVLGLGDGEEAAPPLRSDPEGGDSPLPAPGDPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN", "length": 1237 }, "evidence": [ { "id": "A0A8V1ALB3", "url": "https://omabrowser.org/oma/group/A0A8V1ALB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1252, "end_pos": 1254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 584, "end_pos": 602, "start_aa": "Tyr", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 171, 535 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1252, "end_pos": 1254 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 709, "end_pos": 711 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALK4-1", "uniprot_ac": "A0A8V1ALK4", "uniprot_id": "A0A8V1ALK4_CHICK", "mass": { "chemical_mass": 88485.0, "monoisotopic_mass": 88485.0 }, "refseq": { "ac": "XP_004946342", "name": "TBC1 domain family member 16 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946342" }, "gene_names": [ { "name": "TBC1D16", "type": "recommended", "evidence": [ { "id": "A0A8V1ALK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4" } ] }, { "name": "TBC1D16", "type": "synonym", "evidence": [ { "id": "XP_004946342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946342" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 16 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004946342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946342" } ] }, { "name": "TBC1 domain family member 16", "type": "synonym", "evidence": [ { "id": "A0A8V1ALK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946342.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946342" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBC1D16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4", "locus": { "chromosome": "18", "start_pos": 10223669, "end_pos": 10197888, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029315", "url": "https://www.ensembl.org/id/ENSGALG00010029315" } ] } } ], "crossref": [ { "id": "A0A8V1ALK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "768712", "url": "https://www.ncbi.nlm.nih.gov/gene/768712", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768712", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AHF8", "url": "https://www.orthodb.org/?gene=A0A8V1AHF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJH9", "url": "https://www.orthodb.org/?gene=A0A8V1AJH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALK4", "url": "https://www.orthodb.org/?gene=A0A8V1ALK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004946342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLGRLLRRASSKASDLLTLNPGGSSTSSSILDGEIIYSKNNVCVHPPELLQGLGEHHPGYLCLYMEKDELLGTTLILAWVPNSRIQRQDEEALRYVTPESSPVRKAPRKRGRHAQGFGAAQQASPTEPKGAVILKEDILTVSQLVKDGAYISSPSLDGEKLPQSCAAADGAHQSPQPARSDSGILSTISSQDEQNRSELSVEEGLDCRPEPGEDEGSLELFADDVSRDSTFDSDSDAFSSPFCLSPISEALVKSSSSVFLDNESRDAGDDHVPRSHCCTESPNGSTQSPESSGRAQGEEQQKVGALEQVCGVFRVDLGQMRSLRLFFSDEACTCGQLVVASRESQYKIFHFHHGGLDKVSEVFQQWKYCTETHLKEQVAGKLTDEKTCMQFSIRRPKLPSSETHPEENTYRRLDVSAWLSHLNHCGQVEEEYKLQKAIFFGGIDMSIRGEVWPFLLRYYSYESTSEEREALRVQKRKEYFEIQEKRLSMSPDEQKDFWRKVQFTVDKDVVRTDRSNQFFRGENNPNVETMRRILLNYAVFNPAIGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFISSPRDEDMEKQLMYLRELLRLMHPRFYQHLSALGEDGLQMLFCHRWILLCFKREFPDAEALRMWEACWAHYQTDYFHLFICVAIVVIYGDDVIEQQLATDQMLLHFGNLAMHMNGELVLRKARSLLYQFHLLPRIPCSLHDLCQLCGTGMWDSGFIPAVECSGHHPAAEGCPYGGLVEESSPKPGGEGRRGVKTHDIFNFRK", "length": 784, "header": "tr|A0A8V1ALK4-1|A0A8V1ALK4_CHICK Isoform 1 of TBC1 domain family member 16 OS=Gallus gallus OX=9031 GN=TBC1D16 PE=4 SV=1 CANONICAL=A0A8V1ALK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4/entry#A0A8V1AHF8-1", "sequence": { "sequence": "MSLGRLLRRASSKASDLLTLNPGGSSTSSSILDGEIIYSKNNVCVHPPELLQGLGEHHPGYLCLYMEKDELLGTTLILAWVPNSRIQRQDEEALRYVTPESSPVRKAPRKRGRHAQGFGAAQQASPTEPKGAVILKEDILTVSQLVKDGAYISSPSLDGEKLPQSCAAADGAHQSPQPARSDSGILSTISSQDEQNSEALVKSSSSVFLDNESRDAGDDHVPRSHCCTESPNGSTQSPESSGRAQGEEQQKVGALEQVCGVFRVDLGQMRSLRLFFSDEACTCGQLVVASRESQYKIFHFHHGGLDKVSEVFQQWKYCTETHLKEQLTDEKTCMQFSIRRPKLPSSETHPEENTYRRLDVSAWLSHLNHCGQVEEEYKLQKAIFFGGIDMSIRGEVWPFLLRYYSYESTSEEREALRVQKRKEYFEIQEKRLSMSPDEQKDFWRKVQFTVDKDVVRTDRSNQFFRGENNPNVETMRRILLNYAVFNPAIGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFISSPRDEDMEKQLMYLRELLRLMHPRFYQHLSALGEDGLQMLFCHRWILLCFKREFPDAEALRMWEACWAHYQTDYFHLFICVAIVVIYGDDVIEQQLATDQMLLHFGNLAMHMNGELVLRKARSLLYQFHLLPRIPCSLHDLCQLCGTGMWDSGFIPAVECSGHHPAAEGCPYGGLVEESSPKPGGEGRRGVKTHDIFNFRK", "length": 728, "header": "tr|A0A8V1AHF8-1|A0A8V1ALK4_CHICK Computationally mapped isoform of TBC1 domain family member 16 OS=Gallus gallus OX=9031 GN=TBC1D16 PE=4 SV=1 CANONICAL=A0A8V1ALK4-1" }, "locus": { "chromosome": "18", "start_pos": 10221942, "end_pos": 10203018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070897.1", "url": "https://www.ensembl.org/id/ENSGALT00010070897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043588.1", "url": "https://www.ensembl.org/id/ENSGALP00010043588.1" } ] } }, { "isoform_ac": "A0A8V1AJH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4/entry#A0A8V1AJH9-1", "sequence": { "sequence": "MSLGRLLRRASSKASDLLTLNPGGSSTSSSILDGEIIYSKNNVCVHPPELLQGLGEHHPGYLCLYMEKDELLGTTLILAWVPNSRIQRQDEEALRYVTPESSPVRKAPRKRGRHAQGFGAAQQASPTEPKGAVILKEDILTVSQLVKDGAYISSPSLDGEKLPQSCAAADGAHQSPQPARSDSGILSTISSQDEQNRSELSVEEGLDCRPEPGEDEGSLELFADDVSRDSTFDSDSDAFSSPFCLSPISEALVKSSSSVFLDNESRDAGDDHVPRSHCCTESPNGSTQSPESSGRAQGEEQQKVGALEQVCGVFRVDLGQMRSLRLFFSDEACTCGQLVVASRESQYKIFHFHHGGLDKVSEVFQQWKYCTETHLKEQQLTDEKTCMQFSIRRPKLPSSETHPEENTYRRLDVSAWLSHLNHCGQVEEEYKLQKAIFFGGIDMSIRGEVWPFLLRYYSYESTSEEREALRVQKRKEYFEIQEKRLSMSPDEQKDFWRKVQFTVDKDVVRTDRSNQFFRGENNPNVETMRRILLNYAVFNPAIGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFISSPRDEDMEKQLMYLRELLRLMHPRFYQHLSALGEDGLQMLFCHRWILLCFKREFPDAEALRMWEACWAHYQTDYFHLFICVAIVVIYGDDVIEQQLATDQMLLHFGNLAMHMNGELVLRKARSLLYQFHLLPRIPCSLHDLCQLCGTGMWDSGFIPAVECSGHHPAAEGCPYGGLVEESSPKPGGEGRRGVKTHDIFNFRK", "length": 781, "header": "tr|A0A8V1AJH9-1|A0A8V1ALK4_CHICK Computationally mapped isoform of TBC1 domain family member 16 OS=Gallus gallus OX=9031 GN=TBC1D16 PE=4 SV=1 CANONICAL=A0A8V1ALK4-1" }, "locus": { "chromosome": "18", "start_pos": 10221942, "end_pos": 10203018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070899.1", "url": "https://www.ensembl.org/id/ENSGALT00010070899.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043590.1", "url": "https://www.ensembl.org/id/ENSGALP00010043590.1" } ] } }, { "isoform_ac": "A0A8V1ALK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4/entry#A0A8V1ALK4-1", "sequence": { "sequence": "MSLGRLLRRASSKASDLLTLNPGGSSTSSSILDGEIIYSKNNVCVHPPELLQGLGEHHPGYLCLYMEKDELLGTTLILAWVPNSRIQRQDEEALRYVTPESSPVRKAPRKRGRHAQGFGAAQQASPTEPKGAVILKEDILTVSQLVKDGAYISSPSLDGEKLPQSCAAADGAHQSPQPARSDSGILSTISSQDEQNRSELSVEEGLDCRPEPGEDEGSLELFADDVSRDSTFDSDSDAFSSPFCLSPISEALVKSSSSVFLDNESRDAGDDHVPRSHCCTESPNGSTQSPESSGRAQGEEQQKVGALEQVCGVFRVDLGQMRSLRLFFSDEACTCGQLVVASRESQYKIFHFHHGGLDKVSEVFQQWKYCTETHLKEQVAGKLTDEKTCMQFSIRRPKLPSSETHPEENTYRRLDVSAWLSHLNHCGQVEEEYKLQKAIFFGGIDMSIRGEVWPFLLRYYSYESTSEEREALRVQKRKEYFEIQEKRLSMSPDEQKDFWRKVQFTVDKDVVRTDRSNQFFRGENNPNVETMRRILLNYAVFNPAIGYSQGMSDLVAPILAEVLDESDTFWCFVGLMQNTIFISSPRDEDMEKQLMYLRELLRLMHPRFYQHLSALGEDGLQMLFCHRWILLCFKREFPDAEALRMWEACWAHYQTDYFHLFICVAIVVIYGDDVIEQQLATDQMLLHFGNLAMHMNGELVLRKARSLLYQFHLLPRIPCSLHDLCQLCGTGMWDSGFIPAVECSGHHPAAEGCPYGGLVEESSPKPGGEGRRGVKTHDIFNFRK", "length": 784, "header": "tr|A0A8V1ALK4-1|A0A8V1ALK4_CHICK Isoform 1 of TBC1 domain family member 16 OS=Gallus gallus OX=9031 GN=TBC1D16 PE=4 SV=1 CANONICAL=A0A8V1ALK4-1" }, "locus": { "chromosome": "18", "start_pos": 10221942, "end_pos": 10203018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070898.1", "url": "https://www.ensembl.org/id/ENSGALT00010070898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043589.1", "url": "https://www.ensembl.org/id/ENSGALP00010043589.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768712", "resource": "KEGG Pathway" }, { "id": "R-GGA-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of receptor recycling", "id": "GO:0001919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001919", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALK4" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 443, "end_pos": 653, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANC4-1", "uniprot_ac": "A0A8V1ANC4", "uniprot_id": "A0A8V1ANC4_CHICK", "mass": { "chemical_mass": 43805.0, "monoisotopic_mass": 43805.0 }, "refseq": {}, "gene_names": [ { "name": "MCRIP1", "type": "recommended", "evidence": [ { "id": "A0A8V1ANC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4" } ] } ], "protein_names": [ { "name": "MAPK regulated corepressor interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ANC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCRIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4", "locus": { "chromosome": "18", "start_pos": 10545535, "end_pos": 10550405, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029355", "url": "https://www.ensembl.org/id/ENSGALG00010029355" } ] } } ], "crossref": [ { "id": "A0A8V1ANC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACG1", "url": "https://www.orthodb.org/?gene=A0A8V1ACG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHR3", "url": "https://www.orthodb.org/?gene=A0A8V1AHR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANC4", "url": "https://www.orthodb.org/?gene=A0A8V1ANC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF14799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ACG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GQHGPSAAHVQSPHSCTASRGWGQHEGLFPGLNASVQSVSPETESFTYGALPQRRHLSGPHQAGGPGAGGQVHTYQESGSGHHLPLRNGRPAPSGAHGEPGLRQAPGEVRRRHPPEGRERLDAPAHGLQRRPRRHRQVPPVAGGQPGGHHGRRGEAVGPHRPRIQGPGGAFPGRHDGLRGTGVTAGQRGCAGLGRGPGGVRAGPRGASGRALYFSNKAFGHGARSRCGGGGGGGERGGAGPRDVWAGPRRLGGRDRACALRRFRGGPRASGGGSRAQVRGARCHGDGLRAARGLAPAWPPSPFSPQPRRAEPRRRTHRAMASSPVSRVVYNGKRSGGPRSPGAGSEIFTPAHEENVRFIYEAWQCVERDLRSQMGSERGLVEEYVEKMPNPSLKAFKPVDLSDLKRRNTQDAKKS", "length": 415, "header": "tr|A0A8V1ANC4-1|A0A8V1ANC4_CHICK Isoform 1 of MAPK regulated corepressor interacting protein 1 OS=Gallus gallus OX=9031 GN=MCRIP1 PE=3 SV=1 CANONICAL=A0A8V1ANC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4/entry#A0A8V1ACG1-1", "sequence": { "sequence": "GGTAPARCGASVAARGRAEAGVGPSSPVSRVVYNGKRSGGPRSPGAGSEIFTPAHEENVRFIYEAWQCVERDLRSQMGSERGLVEEYVEKMPNPSLKAFKPVDLSDLKRRNTQDAKKS", "length": 118, "header": "tr|A0A8V1ACG1-1|A0A8V1ACG1_CHICK Computationally mapped isoform of MAPK regulated corepressor interacting protein 1 OS=Gallus gallus OX=9031 GN=MCRIP1 PE=3 SV=1 CANONICAL=A0A8V1ANC4-1" }, "locus": { "chromosome": "18", "start_pos": 10548362, "end_pos": 10547612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070993.1", "url": "https://www.ensembl.org/id/ENSGALT00010070993.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043684.1", "url": "https://www.ensembl.org/id/ENSGALP00010043684.1" } ] } }, { "isoform_ac": "A0A8V1AHR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4/entry#A0A8V1AHR3-1", "sequence": { "sequence": "GQHGPSAAHVQSPHSCTASRGWGQHEGLFPGLNASVQSVSPETESFTYGALPQRRHLSGPHQAGGPGAGGQVHTYQESGSGHHLPLRNGRPAPSGAHGEPGLRQAPGEVRRRHPPEGRERLDAPAHGLQRRPRRHRQVPPVAGGQPGGHHGRRGEAVGPHRPRIQGPGGAFPGRHDGLRGTGVTAGQRGCAGLGRGPGGVRAGPRGASGRALYFSNKAFGHGARSRCGGGGGGGERGGAGPRDVWAGPRRLGGRDRACALRRFRGGPRASGGGSRAQPRRAEPRRRTHRAMASSPVSRVVYNGKRSGGPRSPGAGSEIFTPAHEENVRFIYEAWQCVERDLRSQMGSERGLVEEYVEKMPNPSLKAFKPVDLSDLKRRNTQDAKKS", "length": 386, "header": "tr|A0A8V1AHR3-1|A0A8V1ANC4_CHICK Computationally mapped isoform of MAPK regulated corepressor interacting protein 1 OS=Gallus gallus OX=9031 GN=MCRIP1 PE=3 SV=1 CANONICAL=A0A8V1ANC4-1" }, "locus": { "chromosome": "18", "start_pos": 10550206, "end_pos": 10547612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070995.1", "url": "https://www.ensembl.org/id/ENSGALT00010070995.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043686.1", "url": "https://www.ensembl.org/id/ENSGALP00010043686.1" } ] } }, { "isoform_ac": "A0A8V1ANC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4/entry#A0A8V1ANC4-1", "sequence": { "sequence": "GQHGPSAAHVQSPHSCTASRGWGQHEGLFPGLNASVQSVSPETESFTYGALPQRRHLSGPHQAGGPGAGGQVHTYQESGSGHHLPLRNGRPAPSGAHGEPGLRQAPGEVRRRHPPEGRERLDAPAHGLQRRPRRHRQVPPVAGGQPGGHHGRRGEAVGPHRPRIQGPGGAFPGRHDGLRGTGVTAGQRGCAGLGRGPGGVRAGPRGASGRALYFSNKAFGHGARSRCGGGGGGGERGGAGPRDVWAGPRRLGGRDRACALRRFRGGPRASGGGSRAQVRGARCHGDGLRAARGLAPAWPPSPFSPQPRRAEPRRRTHRAMASSPVSRVVYNGKRSGGPRSPGAGSEIFTPAHEENVRFIYEAWQCVERDLRSQMGSERGLVEEYVEKMPNPSLKAFKPVDLSDLKRRNTQDAKKS", "length": 415, "header": "tr|A0A8V1ANC4-1|A0A8V1ANC4_CHICK Isoform 1 of MAPK regulated corepressor interacting protein 1 OS=Gallus gallus OX=9031 GN=MCRIP1 PE=3 SV=1 CANONICAL=A0A8V1ANC4-1" }, "locus": { "chromosome": "18", "start_pos": 10550206, "end_pos": 10547612, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070994.1", "url": "https://www.ensembl.org/id/ENSGALT00010070994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043685.1", "url": "https://www.ensembl.org/id/ENSGALP00010043685.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALT1-1", "uniprot_ac": "A0A8V1ALT1", "uniprot_id": "A0A8V1ALT1_CHICK", "mass": { "chemical_mass": 176934.0, "monoisotopic_mass": 176934.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC180", "type": "recommended", "evidence": [ { "id": "A0A8V1ALT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 180", "type": "synonym", "evidence": [ { "id": "A0A8V1ALT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC180", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1", "locus": {} } ], "crossref": [ { "id": "IPR027914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAB3", "url": "https://www.orthodb.org/?gene=A0A8V1AAB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFP1", "url": "https://www.orthodb.org/?gene=A0A8V1AFP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHT0", "url": "https://www.orthodb.org/?gene=A0A8V1AHT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK03", "url": "https://www.orthodb.org/?gene=A0A8V1AK03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALT1", "url": "https://www.orthodb.org/?gene=A0A8V1ALT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21444", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21444", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21444:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21444:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AAB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAARGRGGAERVVPNGEVYRQLFEDQARRGRSLGAARSGGRLWLREEPGSTAGEGPWLCDGKAGTAGAKPRQGRAATASQASWRSEDVVAAEEVRALPDLVEVPEESRHNLLELVSERRRGRHDAALTSMHHEFACIAREMEPFVLEPGKVLLTKLMESDRKTEVVLTKMELSATLEGFSIEDLEGLWATIQQESLTRKEWIREWDETLKRVERSRADKITDVLRKHAARLEEISFLLSADVHRLINDEAMMINRALLANQRAVAKLFFNLMKSEMKRELSLQLKWRDRVKDWRLIRKNCIIQSFRDFMAKEEIQNPQTVKTEKENMMNGQILLNEQRLELLQHLTDLLPPTSTQAEIDEWYNSLVDLNSSIDDHNTKCTMKIRAQYESVQQQCLAEVQLCKNNLLNLKVCTQIEAEEVVASDLLLLTEKLRCRFEEELERMVRGFEELAKHNEQNCRDLYSFCQEANVLWDFHRLKLSQQEGELQKKLSECKQKQDKSIQRMETHLDIILHKMRTASSQKKLQKSLESALSCLDGIRARYEASNKALMEIVMSYPEAILQELISYSESLSQYFNVKEVFKQSLEGKTDSTFPGQEEVSDAENQGEQQTESVVQENGEEQKAESCHEQKGGTNIPENEEVFAQASEEGEEQEDRSIFQGSDEPGDVEQRMGFSQDTFDSSREEISELTVETFSTSSGNTYTILGAEEGGKPDVLETSLTKCDEKGSLPMHLEHALVTDTVFVELKKRIRLRFFEHLEKWFAESLSNSWATVGAKKGELSSELQQHLLSCELRRKNIETNIFSVRAAELLLHEKHLECHCNEVGEALKKERAEFLRFCDQQNDSIQNLESRICDMESAFLRTAVAESSSVCPELHHYLDVIRVSLRSYRNYLEETLGTLRDSNVDFLKGCRLFVEGGNFSSEEVQSFSKCLQKESKSIDSFERSILADMEKMESRCLEQATEVIKRAETRLHCLFMNRVFMEKIQRLLANLRVQIKSEVANSNLQAAALKSHLEKLHAFAHPTADKEALTSEELYDFIKAVLKELKARSQYLDCLLVNAARPYDNEHFAPPAAEVALRGPIAAAIRAEHKLAMMGLDAGRFPLLNPSRMGKSAVDDLSVSVIKNLLEVQSPGRKSSVQNQDSSASLGPGKRKSTLTTQKKNSHLSVAGEGPRGSAAHEHAAQVARKPSTKKQSSRGSMQKHSRSVLRDRRFQIFGEMPPESNTFKGIVMNILWTGNNNLLSLAEEFYHTERHQITMPEDLPETFERCAEVIRQNLLSYQSQIDAYYNSCLKEFWDQLKSFEEELPYVSQLAVDGLLKEHEQKLSCATSNIQHSFHQQLEDWRSVKAARENELRPSLGHPDNLLQLEALCQRESKERKDHVDAIHLHTRMLQDCASECTQNFVSALAAFTEKLLLELDESITIGDIQAPKTVTPKEKASMLIHHRQAGLPLQTHGAEQLVERGSRTWPGIPTTTLMGDSDRVTVRETASVTTAKTTLGHIAAVEARDAAYKKYRCELEQQLAQIKEESTSELETVQHWENWWKQSIQKIKQLYM", "length": 1555, "header": "tr|A0A8V1ALT1-1|A0A8V1ALT1_CHICK Isoform 1 of Coiled-coil domain containing 180 OS=Gallus gallus OX=9031 GN=CCDC180 PE=4 SV=1 CANONICAL=A0A8V1ALT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1/entry#A0A8V1AAB3-1", "sequence": { "sequence": "MHHEFACIAREMEPFVLEPGKVLLTKLMESDRKTEVVLTKMELSATLEGFSIEDLEGLWATIQQESLTRKEWIREWDETLKRVERSRADKITDVLRKHAARLEEISFLLSADVHRLINDEAMMINRALLANQRAVAKLFFNLMKSEMKRELSLQLKWRDRVKDWRLIRKNCIIQSFRDFMAKEEIQNPQTVKTEKENMMNGQILLNEQRLELLQHLTDLLPPTSTQAEIDEWYNSLVDLNSSIDDHNTKCTMKIRAQYESVQQQCLAEVQLCKNNLLNLKVCTQIEAEEVVASDLLLLTEKLRCRFEEELERMVRGFEELAKHNEQNCRDLYSFCQEANVLWDFHRLKLSQQEGELQKKLSECKQKQDKSIQRMETHLDIILHKMRTASSQKKLQKSLESALSCLDGIRARYEASNKALMEIVMSYPEAILQELISYSESLSQYFNVKEVFKQSLEGKTDSTFPGQEEVSDAENQGEQQTESVVQENGEEQKAESCHEQKGGTNIPENEEVFAQASEEGEEQEDRSIFQGSDEPGDVEQRMGFSQDTFDSSREEISELTVETFSTSSGNTYTILGAEEGGKPDVLETSLTKCDEKGSLPMHLEHALVTDTVFVELKKRIRLRFFEHLEKWFAESLSNSWATVGAKKGELSSELQQHLLSCELRRKNIETNIFSVRAAELLLHEKHLECHCNEVGEALKKERAEFLRFCDQQNDSIQNLESRICDMESAFLRTAVAESSVCPELHHYLDVIRVSLRSYRNYLEETLGTLRDSNVDFLKGCRLFVEGGNFSSEEVQSFSKCLQKESKSIDSFERSILADMEKMESRCLEQATEVIKRAETRLHCLFMNRVFMEKIQRLLANLRVQIKSEVANSNLQAAALKSHLEKLHAFAHPTADKEALTSEELYDFIKAVLKELKARSQYLDCLLVNAARPYDNEHFAPPAAEVALRGPIAAAIRAEHKLAMMGLDAGRFPLLNPSRMGKSAVDDLSVSVIKNLLEVQSPGRKSSVQNQDSSASLGPGKRKSTLTTQKKNSHLSVAGEGPRGSAAHEHAAQVARKPSTKKQSSRGSTFKGIVMNILWTGNNNLLSLAEEFYHTERHQITMPEDLPETFERCAEVIRQNLLSYQSQIDAYYNSCLKEFWDQLKSFEEELPYVSQLAVDGLLKEHEQKLSCATSNIQHSFHQQLEDWRSVKAARENELRPSLGHPDNLLQLEALCQRESKERKDHVDAIHLHTRMLQDCASECTQNFVSALAAFTEKLLLELDESITIGDIQAPKTVTPKEKASMLIHHRQAGLPLQTHGAEQLVERGSRTWPGIPTTTLMGDSDRVTVRETASVTTAKTTLGHIAAVEARDAAYKKYRCELEQQLAQIKEESTSELETVQHWENWWKQSIQKIKQLYM", "length": 1397, "header": "tr|A0A8V1AAB3-1|A0A8V1AAB3_CHICK Computationally mapped isoform of Coiled-coil domain containing 180 OS=Gallus gallus OX=9031 GN=CCDC180 PE=4 SV=1 CANONICAL=A0A8V1ALT1-1" }, "locus": { "chromosome": "17", "start_pos": 7460215, "end_pos": 7445339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069788.1", "url": "https://www.ensembl.org/id/ENSGALT00010069788.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042917.1", "url": "https://www.ensembl.org/id/ENSGALP00010042917.1" } ] } }, { "isoform_ac": "A0A8V1AFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1/entry#A0A8V1AFP1-1", "sequence": { "sequence": "MAAAAARGRGGAERVVPNGEVYRQLFEDQARRGRSLGAARSGGRLWLREEPGSTAGEGPWLCDGKAGTAGAKPRQGRAATASQASWRSEDVVAAEEVRALPDLVEVPEESRHNLLELVSERRRGRHDAALTSMHHEFACIAREMEPFVLEPGKVLLTKLMESDRKTEVVLTKMELSATLEGFSIEDLEGLWATIQQESLTRKEWIREWDETLKRVERSRADKITDVLRKHAARLEEISFLLSADVHRLINDEAMMINRALLANQRAVAKLFFNLMKSEMKRELSLQLKWRDRVKDWRLIRKNCIIQSFRDFMAKEEIQNPQTVKTEKENMMNGQILLNEQRLELLQHLTDLLPPTSTQAEIDEWYNSLVDLNSSIDDHNTKCTMKIRAQYESVQQQCLAEVQLCKNNLLNLKVCTQIEAEEVVASDLLLLTEKLRCRFEEELERMVRGFEELAKHNEQNCRDLYSFCQEANVLWDFHRLKLSQQEGELQKKLSECKQKQDKSIQRMETHLDIILHKMRTASSQKKLQKSLESALSCLDGIRARYEASNKALMEIVMSYPEAILQELISYSESLSQYFNVKEVFKQSLEGKTDSTFPGQEEVSDAENQGEQQTESVVQENGEEQKAESCHEQKGGTNIPENEEVFAQASEEGEEQEDRSIFQGSDEPGDVEQRMGFSQDTFDSSREEISELTVETFSTSSGNTYTILGAEEGGKPDVLETSLTKCDEKGSLPMHLEHALVTDTVFVELKKRIRLRFFEHLEKWFAESLSNSWATVGAKKGELSSELQQHLLSCELRRKNIETNIFSVRAAELLLHEKHLECHCNEVGEALKKERAEFLRFCDQQNDSIQNLESRICDMESAFLRTAVAESSSVCPELHHYLDVIRVSLRSYRNYLEETLGTLRDSNVDFLKGCRLFVEGGNFSSEEVQSFSKCLQKESKSIDSFERSILADMEKMESRCLEQATEVIKRAETRLHCLFMNRVFMEKIQRLLANLRVQIKSEVANSNLQAAALKSHLEKLHAFAHPTADKEALTSEELYDFIKAVLKELKARSQYLDCLLVNAARPYDNEHFAPPAAEVALRGPIAAAIRAEHKLAMMGLDAGRFPLLNPSRMGKSAVDDLSVSVIKNLLEVQSPGRKSSVQNQDSSASLGPGKRKSTLTTQKKNSHLSVAGEGPRGSAAHEHAAQVARKPSTKKQSSRGSTFKGIVMNILWTGNNNLLSLAEEFYHTERHQITMPEDLPETFERCAEVIRQNLLSYQSQIDAYYNSCLKEFWDQLKSFEEELPYVSQLAVDGLLKEHEQKLSCATSNIQHSFHQQLEDWRSVKAARENELRPSLGHPDNLLQLEALCQRESKERKDHVDAIHLHTRMLQDCASECTQNFVSALAAFTEKLLLELDESITIGDIQAPKTVTPKEKASMLIHHRQAGLPLQTHGAEQLVERGSRTWPGIPTTTLMGDSDRVTVRETASVTTAKTTLGHIAAVEARDAAYKKYRCELEQQLAQIKEESTSELETVQHWENWWKQSIQKIKQLYM", "length": 1530, "header": "tr|A0A8V1AFP1-1|A0A8V1AFP1_CHICK Computationally mapped isoform of Coiled-coil domain containing 180 OS=Gallus gallus OX=9031 GN=CCDC180 PE=4 SV=1 CANONICAL=A0A8V1ALT1-1" }, "locus": { "chromosome": "17", "start_pos": 7462527, "end_pos": 7445339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069792.1", "url": "https://www.ensembl.org/id/ENSGALT00010069792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042919.1", "url": "https://www.ensembl.org/id/ENSGALP00010042919.1" } ] } }, { "isoform_ac": "A0A8V1AHT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1/entry#A0A8V1AHT0-1", "sequence": { "sequence": "MAAAAARGRGGAERVVPNGEVYRQLFEDQARRGRSLGAARSGGRLWLREEPGSTAGEGPWLCDGKAGTAGAKPRQGRAATASQASWRSEDVVAAEEVRALPDLVEVPEESRHNLLELVSERRRGRHDAALTSMHHEFACIAREMEPFVLEPGKVLLTKLMESDRKTEVVLTKMELSATLEGFSIEDLEGLWATIQQESLTRKEWIREWDETLKRVERSRADKITDVLRKHAARLEEISFLLSADVHRLINDEAMMINRALLANQRAVAKLFFNLMKSEMKRELSLQLKWRDRVKDWRLIRKNCIIQSFRDFMAKEEIQNPQTVKTEKENMMNGQILLNEQRLELLQHLTDLLPPTSTQAEIDEWYNSLVDLNSSIDDHNTKCTMKIRAQYESVQQQCLAEVQLCKNNLLNLKVCTQIEAEEVVASDLLLLTEKLRCRFEEELERMVRGFEELAKHNEQNCRDLYSFCQEANVLWDFHRLKLSQQEGELQKKLSECKQKQDKSIQRMETHLDIILHKMRTASSQKKLQKSLESALSCLDGIRARYEASNKALMEIVMSYPEAILQELISYSESLSQYFNVKEVFKQSLEGKTDSTFPGQEEVSDAENQGEQQTESVVQENGEEQKAESCHEQKGGTNIPENEEVFAQASEEGEEQEDRSIFQGSDEPGDVEQRMGFSQDTFDSSREEISELTVETFSTSSGNTYTILGAEEGGKPDVLETSLTKCDEKGSLPMHLEHALVTDTVFVELKKRIRLRFFEHLEKWFAESLSNSWATVGAKKGELSSELQQHLLSCELRRKNIETNIFSVRAAELLLHEKHLECHCNEVGEALKKERAEFLRFCDQQNDSIQNLESRICDMESAFLRTAVAESSSVCPELHHYLDVIRVSLRSYRNYLEETLGTLRDSNVDFLKGCRLFVEGGNFSSEEVQSFSKCLQKESKSIDSFERSILADMEKMESRCLEQATEVIKRAETRLHCLFMNRVFMEKIQRLLANLRVQIKSEVANSNLQAAALKSHLEKLHAFAHPTADKEALTSEELYDFIKAVLKELKARSQYLDCLLVNAARPYDNEHFAPPAAEVALRGPIAAAIRAEHKLAMMGLDAGRFPLLNPSRMGKSAVDDLSVSVIKNLLEVQSPGRKSSVQNQDSSASLGPGKRKSTLTTQKKNSHLSVAGEGPRGSAAHEHAAQVARKPSTKKQSSRGSMQKHSRSVLRDRRFQIFGEMPPESNTFKGIVMNILWTGNNNLLSLAEEFYHTERHQITMPEDLPETFERCAEVIRQNLLSYQSQIDAYYNSCLKEFWDQLKSFEEELPYVSQLAVDGLLKEHEQKLSCATSNIQHSFHQQLEDWRSVKAARENELRPSLGHPDNLLQLEALCQRESKERKDHVDAIHLHTRMLQDCASECTQNFVSALAAFTEKLLLELDESITIGDIQAPSK", "length": 1432, "header": "tr|A0A8V1AHT0-1|A0A8V1ALT1_CHICK Computationally mapped isoform of Coiled-coil domain containing 180 OS=Gallus gallus OX=9031 GN=CCDC180 PE=4 SV=1 CANONICAL=A0A8V1ALT1-1" }, "locus": { "chromosome": "17", "start_pos": 7462527, "end_pos": 7446522, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069794.1", "url": "https://www.ensembl.org/id/ENSGALT00010069794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042921.1", "url": "https://www.ensembl.org/id/ENSGALP00010042921.1" } ] } }, { "isoform_ac": "A0A8V1AK03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1/entry#A0A8V1AK03-1", "sequence": { "sequence": "MAAAAARGRGGAERVVPNGEVYRQLFEDQARRGRSLGAARSGGRLWLREEPGSTAGEGPWLCDGKAGTAGAKPRQGRAATASQASWRSEDVVAAEEVRALPDLVEVPEESRHNLLELVSERRRGRHDAALTSMHHEFACIAREMEPFVLEPGKVLLTKLMESDRKTEVVLTKMELSATLEGFSIEDLEGLWATIQQESLTRKEWIREWDETLKRVERSRADKITDVLRKHAARLEEISFLLSADVHRLINDEAMMINRALLANQRAVAKLFFNLMKSEMKRELSLQLKWRDRVKDWRLIRKNCIIQSFSDLLPPTSTQAEIDEWYNSLVDLNSSIDDHNTKCTMKIRAQYESVQQQCLAEVQLCKNNLLNLKVCTQIEAEEVVASDLLLLTEKLRCRFEEELERMVRGFEELAKHNEQNCRDLYSFCQEANVLWDFHRLKLSQQEGELQKKLSECKQKQDKSIQRMETHLDIILHKMRTASSQKKLQKSLESALSCLDGIRARYEASNKALMEIVMSYPEAILQELISYSESLSQYFNVKEVFKQSLEGKTDSTFPGQEEVSDAENQGEQQTESVVQENGEEQKAESCHEQKGGTNIPENEEVFAQASEEGEEQEDRSIFQGSDEPGDVEQRMGFSQDTFDSSREEISELTVETFSTSSGNTYTILGAEEGGKPDVLETSLTKCDEKGSLPMHLEHALVTDTVFVELKKRIRLRFFEHLEKWFAESLSNSWATVGAKKGELSSELQQHLLSCELRRKNIETNIFSVRAAELLLHEKHLECHCNEVGEALKKERAEFLRFCDQQNDSIQNLESRICDMESAFLRTAVAESSVCPELHHYLDVIRVSLRSYRNYLEETLGTLRDSNVDFLKGCRLFVEGGNFSSEEVQSFSKCLQKESKSIDSFERSILADMEKMESRCLEQATEVIKRAETRLHCLFMNRVFMEKIQRLLANLRVQIKSEVANSNLQAAALKSHLEKLHAFAHPTADKEALTSEELYDFIKAVLKELKARSQYLDCLLVNAARPYDNEHFAPPAAEVALRGPIAAAIRAEHKLAMMGLDAGRFPLLNPSRMGKSAVDDLSVSVIKNLLEVQSPGRKSSVQNQDSSASLGPGKRKSTLTTQKKNSHLSVAGEGPRGSAAHEHAAQVARKPSTKKQSSRGSMQKHSRSVLRDRRFQIFGEMPPESNTFKGIVMNILWTGNNNLLSLAEEFYHTERHQITMPEDLPETFERCAEVIRQNLLSYQSQIDAYYNSCLKEFWDQLKSFEEELPYVSQLAVDGLLKEHEQKLSCATSNIQHSFHQQLEDWRSVKAARENELRPSLGHPDNLLQLEALCQRESKERKDHVDAIHLHTRMLQDCASECTQNFVSALAAFTEKLLLELDESITIGDIQAPKTVTPKEKASMLIHHRQAGLPLQTHGAEQLVERGSRTWPGIPTTTLMGDSDRVTVRETASVTTAKTTLGHIAAVEARDAAYKKYRCELEQQLAQIKEESTSELETVQHWENWWKQSIQKIKQLYM", "length": 1514, "header": "tr|A0A8V1AK03-1|A0A8V1ALT1_CHICK Computationally mapped isoform of Coiled-coil domain containing 180 OS=Gallus gallus OX=9031 GN=CCDC180 PE=4 SV=1 CANONICAL=A0A8V1ALT1-1" }, "locus": { "chromosome": "17", "start_pos": 7462527, "end_pos": 7445339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069793.1", "url": "https://www.ensembl.org/id/ENSGALT00010069793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042920.1", "url": "https://www.ensembl.org/id/ENSGALP00010042920.1" } ] } }, { "isoform_ac": "A0A8V1ALT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1/entry#A0A8V1ALT1-1", "sequence": { "sequence": "MAAAAARGRGGAERVVPNGEVYRQLFEDQARRGRSLGAARSGGRLWLREEPGSTAGEGPWLCDGKAGTAGAKPRQGRAATASQASWRSEDVVAAEEVRALPDLVEVPEESRHNLLELVSERRRGRHDAALTSMHHEFACIAREMEPFVLEPGKVLLTKLMESDRKTEVVLTKMELSATLEGFSIEDLEGLWATIQQESLTRKEWIREWDETLKRVERSRADKITDVLRKHAARLEEISFLLSADVHRLINDEAMMINRALLANQRAVAKLFFNLMKSEMKRELSLQLKWRDRVKDWRLIRKNCIIQSFRDFMAKEEIQNPQTVKTEKENMMNGQILLNEQRLELLQHLTDLLPPTSTQAEIDEWYNSLVDLNSSIDDHNTKCTMKIRAQYESVQQQCLAEVQLCKNNLLNLKVCTQIEAEEVVASDLLLLTEKLRCRFEEELERMVRGFEELAKHNEQNCRDLYSFCQEANVLWDFHRLKLSQQEGELQKKLSECKQKQDKSIQRMETHLDIILHKMRTASSQKKLQKSLESALSCLDGIRARYEASNKALMEIVMSYPEAILQELISYSESLSQYFNVKEVFKQSLEGKTDSTFPGQEEVSDAENQGEQQTESVVQENGEEQKAESCHEQKGGTNIPENEEVFAQASEEGEEQEDRSIFQGSDEPGDVEQRMGFSQDTFDSSREEISELTVETFSTSSGNTYTILGAEEGGKPDVLETSLTKCDEKGSLPMHLEHALVTDTVFVELKKRIRLRFFEHLEKWFAESLSNSWATVGAKKGELSSELQQHLLSCELRRKNIETNIFSVRAAELLLHEKHLECHCNEVGEALKKERAEFLRFCDQQNDSIQNLESRICDMESAFLRTAVAESSSVCPELHHYLDVIRVSLRSYRNYLEETLGTLRDSNVDFLKGCRLFVEGGNFSSEEVQSFSKCLQKESKSIDSFERSILADMEKMESRCLEQATEVIKRAETRLHCLFMNRVFMEKIQRLLANLRVQIKSEVANSNLQAAALKSHLEKLHAFAHPTADKEALTSEELYDFIKAVLKELKARSQYLDCLLVNAARPYDNEHFAPPAAEVALRGPIAAAIRAEHKLAMMGLDAGRFPLLNPSRMGKSAVDDLSVSVIKNLLEVQSPGRKSSVQNQDSSASLGPGKRKSTLTTQKKNSHLSVAGEGPRGSAAHEHAAQVARKPSTKKQSSRGSMQKHSRSVLRDRRFQIFGEMPPESNTFKGIVMNILWTGNNNLLSLAEEFYHTERHQITMPEDLPETFERCAEVIRQNLLSYQSQIDAYYNSCLKEFWDQLKSFEEELPYVSQLAVDGLLKEHEQKLSCATSNIQHSFHQQLEDWRSVKAARENELRPSLGHPDNLLQLEALCQRESKERKDHVDAIHLHTRMLQDCASECTQNFVSALAAFTEKLLLELDESITIGDIQAPKTVTPKEKASMLIHHRQAGLPLQTHGAEQLVERGSRTWPGIPTTTLMGDSDRVTVRETASVTTAKTTLGHIAAVEARDAAYKKYRCELEQQLAQIKEESTSELETVQHWENWWKQSIQKIKQLYM", "length": 1555, "header": "tr|A0A8V1ALT1-1|A0A8V1ALT1_CHICK Isoform 1 of Coiled-coil domain containing 180 OS=Gallus gallus OX=9031 GN=CCDC180 PE=4 SV=1 CANONICAL=A0A8V1ALT1-1" }, "locus": { "chromosome": "17", "start_pos": 7462527, "end_pos": 7445339, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069790.1", "url": "https://www.ensembl.org/id/ENSGALT00010069790.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042918.1", "url": "https://www.ensembl.org/id/ENSGALP00010042918.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1" }, { "id": "PF14643", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14643" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4455", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 586, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ALT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT1" }, { "id": "PF14644", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14644" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4456", "eco_id": "ECO_0000259", "start_pos": 1241, "end_pos": 1443, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 372, "end_pos": 374 }, { "start_pos": 844, "end_pos": 846 }, { "start_pos": 920, "end_pos": 922 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AND6-1", "uniprot_ac": "A0A8V1AND6", "uniprot_id": "A0A8V1AND6_CHICK", "mass": { "chemical_mass": 89296.0, "monoisotopic_mass": 89296.0 }, "refseq": {}, "gene_names": [ { "name": "PIK3R6", "type": "recommended", "evidence": [ { "id": "A0A8V1AND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ] } ], "protein_names": [ { "name": "Phosphoinositide-3-kinase regulatory subunit 6", "type": "synonym", "evidence": [ { "id": "A0A8V1AND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIK3R6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6", "locus": { "chromosome": "18", "start_pos": 2582753, "end_pos": 2605437, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029363", "url": "https://www.ensembl.org/id/ENSGALG00010029363" } ] } } ], "crossref": [ { "id": "A0A8V1AND6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AND6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHT1", "url": "https://www.orthodb.org/?gene=A0A8V1AHT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJT1", "url": "https://www.orthodb.org/?gene=A0A8V1AJT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALU4", "url": "https://www.orthodb.org/?gene=A0A8V1ALU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AND6", "url": "https://www.orthodb.org/?gene=A0A8V1AND6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15593:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15593:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10486", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10486", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389357", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-392451", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9927354", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9927354", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCCNPGPAMESAEVESDILRRVRTLLRELDGHHPACQRDRGMLRWTLHKKIDQNPSNSPILVRILVKELERAERGDYRHYIIPLLHTLMYALIKAPCISDELCSRVYDFCKKLLTLPKPFCTIGLDYAARLKMERTTPGMLYQRMVISEQSLRSDPYPYQEKIFIFADPELLSEAICKALLTDTEAARVSQSPRACMCYVITHTVQAALGEGCDLSALRTRLQGMPSSEVEHWFQEVVMAVECTGSQVAADRGQHVERLQSIYSAILSSSPPGDAPLEGLQGTPLPNPNISFHLWTEDDQLWKELVLFIRPLSQSCEPDRLSQDLDNFEIQDIISDCECCEQTRFSVLSTDSGIERDLPPSAEEPFAPCSADTEQSRLHRKGGIKKKPSPLESVAFLQTGCNGPGTKPAAKVQRRVGIPTEPTAPLLRLHTARIVLLGDDRILGRLAQAYHSLRAQGKEPNEPTYGTSHKPSSLDLGICGHCCCCVPLGTGGERGGKRETRRVFLTPRLNLQFYYVPVTGQPGTPAAANPSATSPEELCEVAAYLGRADPWYESNINTLCHMIPKLATMPSSPSKHLMTDLFITDVIAYYVRMGAQPVCFQVYAVKVFFSSSAQEPAEDVFLTELCAQVQDSISSREVNPTKKKTTLDGPGIDLTVTYRKVVVSDRAKEVSLSLRSTGLSMKAIPANTAEDLACLNVNITEVVRINNLSGRSFSTVANKLKTCNIKIRSTEQRPFTLCLDKDSRRTYRSVVSLEVSPCLEPSYCLQKSRTMKFSLQEAEDVGLVKYMPKSLLLPINTFAGVIQ", "length": 804, "header": "tr|A0A8V1AND6-1|A0A8V1AND6_CHICK Isoform 1 of Phosphoinositide-3-kinase regulatory subunit 6 OS=Gallus gallus OX=9031 GN=PIK3R6 PE=4 SV=1 CANONICAL=A0A8V1AND6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6/entry#A0A8V1AHT1-1", "sequence": { "sequence": "MLCCNPGPAMESAEVESDILRRVRTLLRELDGHHPACQRDRGMLRWTLHKKIDQNPSNSPILVRILVKELERAERGDYRHYIIPLLHTLMYALIKAPCISDELCSRVYDFCKKLLTLPKPFCTIGLDYAARLKMERTTPGMLYQRMVISEQSLRSDPYPYQEKIFIFADPELLSEAICKALLTDTEAARVSQSPRACMCYVITHTVQAALGEGCDLSALRTRLQHLLLHLGALTAPLWQGMPSSEVEHWFQEVVMAVECTGSQVAADRGQHVERLQSIYSAILSSSPPGDAPLEGLQGTPLPNPNISFHLWTEDDQLWKELVLFIRPLSQSCEPDRLSQDLDNFEIQDIISDCECCEQTRFSVLSTDSGIERDLPPSAEEPFAPCSADTEQSRLHRKGGIKKKPSPLESVAFLQTGCNGPGTKPAAKVQRRVGIPTEPTAPLLRLHTARIVLLGDDRILGRLAQAYHSLRKRETRRVFLTPRLNLQFYYVPVTGQPGTPAAANPSATSPEELCEVAAYLGRADPWYESNINTLCHMIPKLATMPSSPSKHLMTDLFITDVIAYYVRMGAQPVCFQVYAVKVFFSSSAQEPAEDVFLTELCAQVQDSISSREVNPTKKKTTLDGPGIDLTVTYRKVVVSDRAKEVSLSLRSTGLSMKAIPANTAEDLACLNVNITEVVRINNLSGRSFSTVANKLKTCNIKIRSTEQRPFTLCLDKDSRRTYRSVVSLEVSPCLEPSYCLQKSRTMKFSLQEAEDVGLVKYMPKSLLLPINTFAGVIQ", "length": 777, "header": "tr|A0A8V1AHT1-1|A0A8V1AND6_CHICK Computationally mapped isoform of Phosphoinositide-3-kinase regulatory subunit 6 OS=Gallus gallus OX=9031 GN=PIK3R6 PE=4 SV=1 CANONICAL=A0A8V1AND6-1" }, "locus": { "chromosome": "18", "start_pos": 2597470, "end_pos": 2584527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071010.1", "url": "https://www.ensembl.org/id/ENSGALT00010071010.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043701.1", "url": "https://www.ensembl.org/id/ENSGALP00010043701.1" } ] } }, { "isoform_ac": "A0A8V1AJT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6/entry#A0A8V1AJT1-1", "sequence": { "sequence": "MLCCNPGPAMESAGMLRWTLHKKIDQNPSNSPILVRILVKELERAERGDYRHYIIPLLHTLMYALIKAPCISDELCSRVYDFCKKLLTLPKPFCTIGLDYAARLKMERTTPGMLYQRMVISEQSLRSDPYPYQEKIFIFADPELLSEAICKALLTDTEAARVSQSPRACMCYVITHTVQAALGEGCDLSALRTRLQGMPSSEVEHWFQEVVMAVECTGSQVAADRGQHVERLQSIYSAILSSSPPGDAPLEGLQGTPLPNPNISFHLWTEDDQLWKELVLFIRPLSQSCEPDRLSQDLDNFEIQDIISDCECCEQTRFSVLSTDSGIERDLPPSAEEPFAPCSADTEQSRLHRKGGIKKKPSPLESVAFLQTGCNGPGTKPAAKVQRRVGIPTEPTAPLLRLHTARIVLLGDDRILGRLAQAYHSLRKRETRRVFLTPRLNLQFYYVPVTGQPGTPAAANPSATSPEELCEVAAYLGRADPWYESNINTLCHMIPKLATMPSSPSKHLMTDLFITDVIAYYVRMGAQPVCFQVYAVKVFFSSSAQEPAEDVFLTELCAQVQDSISSREVNPTKKKTTLDGPGIDLTVTYRKVVVSDRAKEVSLSLRSTGLSMKAIPANTAEDLACLNVNITEVVRINNLSGRSFSTVANKLKTCNIKIRSTEQRPFTLCLDKDSRRTYRSVVSLEVSPCLEPSYCLQKSRTMKFSLQEAEDVGLVKYMPKSLLLPINTFAGVIQ", "length": 734, "header": "tr|A0A8V1AJT1-1|A0A8V1AND6_CHICK Computationally mapped isoform of Phosphoinositide-3-kinase regulatory subunit 6 OS=Gallus gallus OX=9031 GN=PIK3R6 PE=4 SV=1 CANONICAL=A0A8V1AND6-1" }, "locus": { "chromosome": "18", "start_pos": 2597470, "end_pos": 2584527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071012.1", "url": "https://www.ensembl.org/id/ENSGALT00010071012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043703.1", "url": "https://www.ensembl.org/id/ENSGALP00010043703.1" } ] } }, { "isoform_ac": "A0A8V1ALU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6/entry#A0A8V1ALU4-1", "sequence": { "sequence": "MLCCNPGPAMESAEVESDILRRVRTLLRELDGHHPACQRDRGMLRWTLHKKIDQNPSNSPILVRILVKELERAERGDYRHYIIPLLHTLMYALIKAPCISDELCSRVYDFCKKLLTLPKPFCTIGLDYAARLKMERTTPGMLYQRMVISEQSLRSDPYPYQEKIFIFADPELLSEAICKALLTDTEAARVSQSPRACMCYVITHTVQAALGEGCDLSALRTRLQGMPSSEVEHWFQEVVMAVECTGSQVAADRGQHVERLQSIYSAILSSSPPGDAPLEGLQGTPLPNPNISFHLWTEDDQLWKELVLFIRPLSQSCEPDRLSQDLDNFEIQDIISDCECCEQTRFSVLSTDSGIERDLPPSAEEPFAPCSADTEQSRLHRKGGIKKKPSPLESVAFLQTGCNGPGTKPAAKVQRRVGIPTEPTAPLLRLHTARIVLLGDDRILGRLAQAYHSLRKRETRRVFLTPRLNLQFYYVPVTGQPGTPAAANPSATSPEELCEVAAYLGRADPWYESNINTLCHMIPKLATMVFFSSSAQEPAEDVFLTELCAQVQDSISSREVNPTKKKTTLDGPGIDLTVTYRKVVVSDRAKEVSLSLRSTGLSMKAIPANTAEDLACLNVNITEVVRINNLSGRSFSTVANKLKTCNIKIRSTEQRPFTLCLDKDSRRTYRSVVSLEVSPCLEPSYCLQKSRTMKFSLQEAEDVGLVKYMPKSLLLPINTFAGVIQ", "length": 725, "header": "tr|A0A8V1ALU4-1|A0A8V1ALU4_CHICK Computationally mapped isoform of Phosphoinositide-3-kinase regulatory subunit 6 OS=Gallus gallus OX=9031 GN=PIK3R6 PE=4 SV=1 CANONICAL=A0A8V1AND6-1" }, "locus": { "chromosome": "18", "start_pos": 2597470, "end_pos": 2584527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071011.1", "url": "https://www.ensembl.org/id/ENSGALT00010071011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043702.1", "url": "https://www.ensembl.org/id/ENSGALP00010043702.1" } ] } }, { "isoform_ac": "A0A8V1AND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6/entry#A0A8V1AND6-1", "sequence": { "sequence": "MLCCNPGPAMESAEVESDILRRVRTLLRELDGHHPACQRDRGMLRWTLHKKIDQNPSNSPILVRILVKELERAERGDYRHYIIPLLHTLMYALIKAPCISDELCSRVYDFCKKLLTLPKPFCTIGLDYAARLKMERTTPGMLYQRMVISEQSLRSDPYPYQEKIFIFADPELLSEAICKALLTDTEAARVSQSPRACMCYVITHTVQAALGEGCDLSALRTRLQGMPSSEVEHWFQEVVMAVECTGSQVAADRGQHVERLQSIYSAILSSSPPGDAPLEGLQGTPLPNPNISFHLWTEDDQLWKELVLFIRPLSQSCEPDRLSQDLDNFEIQDIISDCECCEQTRFSVLSTDSGIERDLPPSAEEPFAPCSADTEQSRLHRKGGIKKKPSPLESVAFLQTGCNGPGTKPAAKVQRRVGIPTEPTAPLLRLHTARIVLLGDDRILGRLAQAYHSLRAQGKEPNEPTYGTSHKPSSLDLGICGHCCCCVPLGTGGERGGKRETRRVFLTPRLNLQFYYVPVTGQPGTPAAANPSATSPEELCEVAAYLGRADPWYESNINTLCHMIPKLATMPSSPSKHLMTDLFITDVIAYYVRMGAQPVCFQVYAVKVFFSSSAQEPAEDVFLTELCAQVQDSISSREVNPTKKKTTLDGPGIDLTVTYRKVVVSDRAKEVSLSLRSTGLSMKAIPANTAEDLACLNVNITEVVRINNLSGRSFSTVANKLKTCNIKIRSTEQRPFTLCLDKDSRRTYRSVVSLEVSPCLEPSYCLQKSRTMKFSLQEAEDVGLVKYMPKSLLLPINTFAGVIQ", "length": 804, "header": "tr|A0A8V1AND6-1|A0A8V1AND6_CHICK Isoform 1 of Phosphoinositide-3-kinase regulatory subunit 6 OS=Gallus gallus OX=9031 GN=PIK3R6 PE=4 SV=1 CANONICAL=A0A8V1AND6-1" }, "locus": { "chromosome": "18", "start_pos": 2597470, "end_pos": 2584527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071009.1", "url": "https://www.ensembl.org/id/ENSGALT00010071009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043700.1", "url": "https://www.ensembl.org/id/ENSGALP00010043700.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 525, "start_aa": "Thr", "end_pos": 525, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr525", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-114604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114604", "resource": "Reactome", "description": "GPVI-mediated activation cascade" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-GGA-389357", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "resource": "Reactome", "description": "CD28 dependent PI3K/Akt signaling" }, { "id": "R-GGA-392451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392451", "resource": "Reactome", "description": "G beta:gamma signalling through PI3Kgamma" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-9927354", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9927354", "resource": "Reactome", "description": "Co-stimulation by ICOS" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "phosphatidylinositol 3-kinase complex, class IB", "id": "GO:0005944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase complex", "id": "GO:0005942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005942", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "1-phosphatidylinositol-3-kinase regulator activity", "id": "GO:0046935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity", "id": "GO:0046934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046934", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" }, { "name": "positive regulation of T cell differentiation", "id": "GO:0045582", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045582", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" }, { "name": "regulation of natural killer cell mediated cytotoxicity", "id": "GO:0042269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AND6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALY0-1", "uniprot_ac": "A0A8V1ALY0", "uniprot_id": "A0A8V1ALY0_CHICK", "mass": { "chemical_mass": 112499.0, "monoisotopic_mass": 112499.0 }, "refseq": { "ac": "XP_046758506", "name": "general transcription factor II-I isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758506" }, "gene_names": [ { "name": "GTF2I", "type": "recommended", "evidence": [ { "id": "A0A8V1ALY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ] }, { "name": "GTF2I", "type": "synonym", "evidence": [ { "id": "XP_046758506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758506" } ] } ], "protein_names": [ { "name": "Ral transcription factor IIi", "type": "synonym", "evidence": [ { "id": "A0A8V1ALY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0/entry#names_and_taxonomy" } ] }, { "name": "general transcription factor II-I isoform X2", "type": "synonym", "evidence": [ { "id": "XP_046758506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758506" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758506" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTF2I", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0", "locus": { "chromosome": "19", "start_pos": 3147302, "end_pos": 3199000, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029379", "url": "https://www.ensembl.org/id/ENSGALG00010029379" } ] } } ], "crossref": [ { "id": "A0A8V1ALY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "417486", "url": "https://www.ncbi.nlm.nih.gov/gene/417486", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417486", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417486", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEAWNAK", "url": "https://omabrowser.org/oma/group/TEAWNAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHY2", "url": "https://www.orthodb.org/?gene=A0A8V1AHY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALY0", "url": "https://www.orthodb.org/?gene=A0A8V1ALY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANH1", "url": "https://www.orthodb.org/?gene=A0A8V1ANH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47831", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47831", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47831:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47831:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046758506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLGAAFQLLRRMAQATVAATSVPDEDPSESRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVDSRKDFQKDFVKYCVVEGERAAELQETKCVLPANRLTVDAVELEALRKSVEDYFCFCYGKALGKSTVVPVPYEKIQRDQSAVVVQGLPEGLAFMHPANYDVSTLKWILEHKSGISFIIKRPFLEPKKHPGAHVTDPSQSIIPPGGSCPPVQVKTEPSEDSGISLEMSTVTVKEEPEDPDYYQYNIPGVPSETSEMDERIALAKSYTDSSQHPPSETREDPEVEVTLEDDEDYLPPNKRSKNTETANEAASTGRRKTREFNFDKWNARITDLRKQVEELFEKKYAQAIKAKGPVAVPYALFQSHVEDLYVEGLPEGVPFRRPSMYGIPRLERILVAKERIRFVIKKHELLNSTQEDEPVDKPAAGVKEEWYAKINKLRKTVDQLFCKKFAEALGSTEPKAVPYQKFEVHSADLYVEGLPENIPFRSPAWYGIPRLEKIIQVGNRIKFVIKRPELLTLSSPEVTQPGTNTSGKTAKEDWNIRITKLRKQVEEIFNMKFALALGLSEAVKVPYPVFESNPEHLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIRFVVKKPELVASYLPPRLASQINTKGASPKSSKRLQSPASNLQVPEIEVTVEEGPNKAQTADVQTNSQTNGSNTSFKPRGRDFSFEAWNAKITDLKQKVENLFNEKCGEALGLSEPVKVPFALFESFPEVFYVEGLPDGVPFRRPSTFGIPRLEKILRNKSKIKFIIKKPEMFEAAVKESSAKSPQRKNSPSNTANTASTTANTAVSTAAGVEDLNIIQVTLLDDESERLSKVEKARQLREQVNNLFNRKFGEAIGMNFPVKVPYRKITVNPGCVVVDGMPPGVSFKAPSYLEISSMRKILESSEFIKFTVIRPFPGLVMNNQLMEKAEAEAPPTAAAPAAPAVPEPAEPRQTEVSSGDVTETEESCQIKQEPDPTW", "length": 1007, "header": "tr|A0A8V1ALY0-1|A0A8V1ALY0_CHICK Isoform 1 of Ral transcription factor IIi OS=Gallus gallus OX=9031 GN=GTF2I PE=1 SV=1 CANONICAL=A0A8V1ALY0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AHY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0/entry#A0A8V1AHY2-1", "sequence": { "sequence": "MAQATVAATSVPDEDPSESRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVDSRKDFQKDFVKYCVVEGERAAELQETKCVLPANRLTVDAVELEALRKSVEDYFCFCYGKALGKSTVVPVPYEKIQRDQSAVVVQGLPEGLAFMHPANYDVSTLKWILEHKSGISFIIKRPFLEPKKHPGAHVTDPSQSIIPPGGSCPPVQVKTEPSEDSGISLEMSTVTVKEEPEDPDYYQYNIPGVPSETSEMDERIALAKSYTDSSQHPPSETREDPEVEVTLEDDEDYLPPNKRSKNTETANEAASTGRRKTREFNFDKWNARITDLRKQVEELFEKKYAQAIKAKGPVAVPYALFQSHVEDLYVEGLPEGVPFRRPSMYGIPRLERILVAKERIRFVIKKHELLNSTQEDEPVDKPAAGVKEEWYAKINKLRKTVDQLFCKKFAEALGSTEPKAVPYQKFEVHSADLYVEGLPENIPFRSPAWYGIPRLEKIIQVGNRIKFVIKRPELLTLSSPEVTQPGTNTSGKTAKEDWNIRITKLRKQVEEIFNMKFALALGLSEAVKVPYPVFESNPEHLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIRFVVKKPELVASYLPPRLASQINTKGASPKSSKRLQSPASNLQVPEIEVTVEEGPNKAQTADVQTNSQTNGSNTSFKPRGRDFSFEAWNAKITDLKQKVENLFNEKCGEALGLSEPVKVPFALFESFPEVFYVEGLPDGVPFRRPSTFGIPRLEKILRNKSKIKFIIKKPEMFEAAVKESSAKSPQRKNSPSNTANTASTTANTAVSTAAGVEDLNIIQVTLLDDESERLSKVEKARQLREQVNNLFNRKFGEAIGMNFPVKVPYRKITVNPGCVVVDGMPPGVSFKAPSYLEISSMRKILESSEFIKFTVIRPFPGLVMNNQLMEKAEAEAPPTAAAPAAPAVPEPAEPRQTEVSSGDVTETEESCQIKQEPDPTW", "length": 995, "header": "tr|A0A8V1AHY2-1|A0A8V1ALY0_CHICK Computationally mapped isoform of Ral transcription factor IIi OS=Gallus gallus OX=9031 GN=GTF2I PE=1 SV=1 CANONICAL=A0A8V1ALY0-1" }, "locus": { "chromosome": "19", "start_pos": 3195495, "end_pos": 3150039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071056.1", "url": "https://www.ensembl.org/id/ENSGALT00010071056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043747.1", "url": "https://www.ensembl.org/id/ENSGALP00010043747.1" } ] } }, { "isoform_ac": "A0A8V1ALY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0/entry#A0A8V1ALY0-1", "sequence": { "sequence": "MRLGAAFQLLRRMAQATVAATSVPDEDPSESRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVDSRKDFQKDFVKYCVVEGERAAELQETKCVLPANRLTVDAVELEALRKSVEDYFCFCYGKALGKSTVVPVPYEKIQRDQSAVVVQGLPEGLAFMHPANYDVSTLKWILEHKSGISFIIKRPFLEPKKHPGAHVTDPSQSIIPPGGSCPPVQVKTEPSEDSGISLEMSTVTVKEEPEDPDYYQYNIPGVPSETSEMDERIALAKSYTDSSQHPPSETREDPEVEVTLEDDEDYLPPNKRSKNTETANEAASTGRRKTREFNFDKWNARITDLRKQVEELFEKKYAQAIKAKGPVAVPYALFQSHVEDLYVEGLPEGVPFRRPSMYGIPRLERILVAKERIRFVIKKHELLNSTQEDEPVDKPAAGVKEEWYAKINKLRKTVDQLFCKKFAEALGSTEPKAVPYQKFEVHSADLYVEGLPENIPFRSPAWYGIPRLEKIIQVGNRIKFVIKRPELLTLSSPEVTQPGTNTSGKTAKEDWNIRITKLRKQVEEIFNMKFALALGLSEAVKVPYPVFESNPEHLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIRFVVKKPELVASYLPPRLASQINTKGASPKSSKRLQSPASNLQVPEIEVTVEEGPNKAQTADVQTNSQTNGSNTSFKPRGRDFSFEAWNAKITDLKQKVENLFNEKCGEALGLSEPVKVPFALFESFPEVFYVEGLPDGVPFRRPSTFGIPRLEKILRNKSKIKFIIKKPEMFEAAVKESSAKSPQRKNSPSNTANTASTTANTAVSTAAGVEDLNIIQVTLLDDESERLSKVEKARQLREQVNNLFNRKFGEAIGMNFPVKVPYRKITVNPGCVVVDGMPPGVSFKAPSYLEISSMRKILESSEFIKFTVIRPFPGLVMNNQLMEKAEAEAPPTAAAPAAPAVPEPAEPRQTEVSSGDVTETEESCQIKQEPDPTW", "length": 1007, "header": "tr|A0A8V1ALY0-1|A0A8V1ALY0_CHICK Isoform 1 of Ral transcription factor IIi OS=Gallus gallus OX=9031 GN=GTF2I PE=1 SV=1 CANONICAL=A0A8V1ALY0-1" }, "locus": { "chromosome": "19", "start_pos": 3198105, "end_pos": 3150039, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071057.1", "url": "https://www.ensembl.org/id/ENSGALT00010071057.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043748.1", "url": "https://www.ensembl.org/id/ENSGALP00010043748.1" } ] } }, { "isoform_ac": "A0A8V1ANH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0/entry#A0A8V1ANH1-1", "sequence": { "sequence": "MRLGAAFQLLRRMAQATVAATSVPDEDPSESRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVDSRKDFQKDFVKYCKSQRCFFVFHSNCLMYIAKH", "length": 112, "header": "tr|A0A8V1ANH1-1|A0A8V1ANH1_CHICK Computationally mapped isoform of Ral transcription factor IIi OS=Gallus gallus OX=9031 GN=GTF2I PE=1 SV=1 CANONICAL=A0A8V1ALY0-1" }, "locus": { "chromosome": "19", "start_pos": 3198105, "end_pos": 3194208, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071055.1", "url": "https://www.ensembl.org/id/ENSGALT00010071055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043746.1", "url": "https://www.ensembl.org/id/ENSGALP00010043746.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 965, "start_aa": "Thr", "end_pos": 965, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr965", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417486", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417486", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A7MB80-1", "protein_name": "General transcription factor II-I", "gene_name": "GTF2I", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQVAVSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTAQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVMVTDAERSMISPSGSCGPVKVKTEPSEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDDKLPLSKSLQGSHHSSEGNEGTEMEVPAEDDDYPPPAKRPKSSEPPQPPVTEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNSNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSSKSPPRKINSSPSVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEPTQLEVPATEEIKETDGNSQIKQEPDPTW", "length": 978 }, "evidence": [ { "id": "A0A8V1ALY0", "url": "https://omabrowser.org/oma/group/A0A8V1ALY0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RJL2-1", "protein_name": "General transcription factor II-I", "gene_name": "GTF2I", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVMVTDTERSMLSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDDKLPLSKSLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPTKRPKSNEPPQPPVTEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNSNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESSEPSQLEVPATEEIKETDGNSQIKQEPDPTW", "length": 999 }, "evidence": [ { "id": "A0A8V1ALY0", "url": "https://omabrowser.org/oma/group/A0A8V1ALY0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P78347-1", "protein_name": "General transcription factor II-I", "gene_name": "GTF2I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW", "length": 998 }, "evidence": [ { "id": "A0A8V1ALY0", "url": "https://omabrowser.org/oma/group/A0A8V1ALY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U2Y1-1", "protein_name": "General transcription factor II-I", "gene_name": "Gtf2i", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQVAMSALPAEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKCTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVAVQGLPEGVAFKHPEHYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVMAADADRPMLSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGAEVEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPTKRPKSSEPPPPPPVPEPTNAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAYPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVVSYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNSPQTSTVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKTNSSPSVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEASQLEVPATEEIKETDGSSQIKQEPDPTW", "length": 979 }, "evidence": [ { "id": "A0A8V1ALY0", "url": "https://omabrowser.org/oma/group/A0A8V1ALY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ESZ8-1", "protein_name": "General transcription factor II-I", "gene_name": "Gtf2i", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQVVMSALPAEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPEHYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVLAAEAERSMLSPSGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGPSETDGVDEKLPLSKALQGSHHSSEGNEGTEVEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPTKRLKSTEPPPPPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVVSYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNSSPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEASQLEVPVTEEIKETDGSSQIKQEPDPTW", "length": 998 }, "evidence": [ { "id": "A0A8V1ALY0", "url": "https://omabrowser.org/oma/group/A0A8V1ALY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 965 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 428, "end_pos": 430 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 700, "end_pos": 702 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 789, "end_pos": 791 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANI3-1", "uniprot_ac": "A0A8V1ANI3", "uniprot_id": "A0A8V1ANI3_CHICK", "mass": { "chemical_mass": 214980.0, "monoisotopic_mass": 214980.0 }, "refseq": { "ac": "XP_004946595", "name": "WD repeat-containing protein 81 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946595" }, "gene_names": [ { "name": "WDR81", "type": "recommended", "evidence": [ { "id": "A0A8V1ANI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ] }, { "name": "WDR81", "type": "synonym", "evidence": [ { "id": "XP_004946595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946595" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 81", "type": "recommended", "evidence": [ { "id": "A0A8V1ANI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 81 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004946595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946595" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946595.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946595" } ] }, { "annotation": "Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated protein aggregates. In this process, may regulate the interaction of SQSTM1 with ubiquitinated proteins and also recruit MAP1LC3C. May also be involved in maintenance of normal mitochondrial structure and organization.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3#function" }, { "database": "UniProtKB", "id": "ARBA00058689", "url": "https://www.uniprot.org/uniprotkb/ARBA00058689#function" }, { "database": "UniProtKB", "id": "A0A8V1ACP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP1#function" }, { "database": "UniProtKB", "id": "A0A8V1AI00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI00#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR81", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3", "locus": { "chromosome": "19", "start_pos": 5879230, "end_pos": 5867587, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029384", "url": "https://www.ensembl.org/id/ENSGALG00010029384" } ] } } ], "crossref": [ { "id": "cd06071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417560", "url": "https://www.ncbi.nlm.nih.gov/gene/417560", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417560", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417560", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYEQFTP", "url": "https://omabrowser.org/oma/group/AYEQFTP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACP1", "url": "https://www.orthodb.org/?gene=A0A8V1ACP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AI00", "url": "https://www.orthodb.org/?gene=A0A8V1AI00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANI3", "url": "https://www.orthodb.org/?gene=A0A8V1ANI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44662", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44662", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44662:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44662:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02138", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02138", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946595", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI00", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAVGCPQQPRTQGGSGAAGTCPARGHRDRGATMDALLRSVEKDLSINRWQLAAASDGTHVTALVPHKWLANLRERRALPALCPRPEGLSEVEVRTFLQRSVQKLPAGWTRVEIHGLCKERLTWPLRVPPVADPRGGGAETLHGFMQRVASQNYRNLWGRAHCLYVRPYRHAHAPPAVPVLDALRAALQKAYGCPILQVGRSVPSASPAKGISSVPSSCPNVLQAEALLESAEMLYIIYPYVQYCLHDIVTFSPAKLTNSHAKILFLLFHVLQAMRACHQAGLACGAFSLRDVAVDEKLCSRLRVNFREYEGPRKEETNAEADLERVNEQSGAGMRGDVARCYTCQQELRDLVLQWVHGRVSNFDYLMHLNSLAGRRMGDPNYHPVLPWVVDFTTKNGKFRDLRKSKFRLNKGDKQLDFTYEMTKQAFVAGGSSGEQLHVPHHISDVLSDITYYVYTARRTPKSVLCCHVRSQWEPNEYPASMERMQSWTPDECIPEFYTDPSIFRSIHPDMPDLDVPSWCSSYEEFIEVHRMLLESREVSQDLHHWIDLTFGYKLQGKDAVKEKNVCLHLVDNHTHLTTYGVVQLFDQPHPRRMVGPACTPAEAPAIARPLLQNIKETVILEDIPCPVTDAVNGLVLEATPTETTWSGEKPITGEDDLEQGTEALDSISVSSRAPDQPCSSSAQPSTLPAYPTEGKASGVRPLRRSKAGAADQADRDDMKITLPEGFNPLQALEELEKLDNFLVKGLSSDMQLMEQPGEEPLLGLSDLFQRDMQALGILIAEIIFAPRIRPSKPDASLLERFLMVRNLCRYHPKEIPAPLQHVLHILLQLSVPVEKLLKTRLGKDTVQLFEYKPISQGLPPPCPTQLLSPFSSIIPFPTYFPALHKFIFTYQAKKIEDEGQGRELVFQLWQQLEGILSEITPEGLEILLPFILSLMSEENTAVYAAWYLFEPIAKSLGPKNANKYLLKPLIGAYETPCSRHGRFYLYTDCFVAQLIVRLGLQSFILNLLPHILQILVGIESSREESKSLLGAAEDDESGGGSPMSCMFGEEIKMDVEHSSTALDLLDYTSGVSFHDQAYLPESEDFQSGLYVGESLQPQEQESLSLGRLSDKSSASEVSLGEDRPADGDSQKDKSSLKSVDSSQDLKQSEDSEEEEEEREEEERDDTAVDAELVGAVDVGVSVDAGTSVDVTLADDGSEPEDGEGEELPDHSDDKEQTILLDTACKMVRWLSAKLGPTVTSRFIARNLLRLLTSCYIGPTRQQFVPSNDENGPLSTGNIYQKRPVLGDQVSKPVLACLLHVAYLYGEPVLTYQYLPYISYLVAPGSGSGGGRLNSRKEAGLLAAVTLTQKIVVCLSDTTLMDILPKISQEVLLPVLGFLTSLSVGFPSGAQARVVLCIKTISLIALICLRIGQEMVQQHLSDTVRNFFGAFSLLQELQDQGLTAESLSGCEVPVMEVPLREGKLLALDPAVLLELQKVFNPEMAYITYIPFSCLLGDVIRTVVPNHSLVEKLASLYLENVNPKNLQVVGLEQAPSMAGSDQDMRGTEAFSSPQEDSHSGTFGSVLVGNRIQVPVDTQREGLGLLRLSAGTDGFIPSSSSEENTLKHDLPRSTHVLCGNWLAYWQYEIGVSQHDPRFHFHQIKLQSFSGHSGAIKCVAPLSSEDFFLSGSKDKTVRLWPLYNYGDGTSEVPPRFTYSEHKKSVFYVSQLEASQHVVSCDGTVHIWDQFTGKLIRTFDELDSKAPITAVTTMPPPYHSISVASADSVLRFIDHRKPGLQHEFRLAGGVNAGLIRCLAVSPNGRSVMAGFSSGFIVLLDTRTGLIMRGWPAHEGDILQIKAAEGNVLISSSSDHSMTVWKELEQKPLHHYKSASEPIHAFDLYGNEVVTGTVANKIGVYSMLESSALPVSTTKLSSENFRGTLTSLAVLPMKCHLLLGSDNGVIRLLA", "length": 1946, "header": "tr|A0A8V1ANI3-1|A0A8V1ANI3_CHICK Isoform 1 of WD repeat-containing protein 81 OS=Gallus gallus OX=9031 GN=WDR81 PE=1 SV=1 CANONICAL=A0A8V1ANI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3/entry#A0A8V1ACP1-1", "sequence": { "sequence": "MAAGPLPGATMDALLRSVEKDLSINRWQLAAASDGTHVTALVPHKWLANLRERRALPALCPRPEGLSEVEVRTFLQRSVQKLPAGWTRVEIHGLCKERLTWPLRVPPVADPRGGGAETLHGFMQRVASQNYRNLWGRAHCLYVRPYRHAHAPPAVPVLDALRAALQKAYGCPILQVGRSVPSASPAKGISSVPSSCPNVLQAEALLESAEMLYIIYPYVQYCLHDIVTFSPAKLTNSHAKILFLLFHVLQAMRACHQAGLACGAFSLRDVAVDEKLCSRLRVNFREYEGPRKEETNAEADLERVNEQSGAGMRGDVARCYTCQQELRDLVLQWVHGRVSNFDYLMHLNSLAGRRMGDPNYHPVLPWVVDFTTKNGKFRDLRKSKFRLNKGDKQLDFTYEMTKQAFVAGGSSGEQLHVPHHISDVLSDITYYVYTARRTPKSVLCCHVRSQWEPNEYPASMERMQSWTPDECIPEFYTDPSIFRSIHPDMPDLDVPSWCSSYEEFIEVHRMLLESREVSQDLHHWIDLTFGYKLQGKDAVKEKNVCLHLVDNHTHLTTYGVVQLFDQPHPRRMVGPACTPAEAPAIARPLLQNIKETVILEDIPCPVTDAVNGLVLEATPTETTWSGEKPITGEDDLEQGTEALDSISVSSRAPDQPCSSSAQPSTLPAYPTEGKASGVRPLRRSKAGAADQADRDDMKITLPEGFNPLQALEELEKLDNFLVKGLSSDMQLMEQPGEEPLLGLSDLFQRDMQALGILIAEIIFAPRIRPSKPDASLLERFLMVRNLCRYHPKEIPAPLQHVLHILLQLSVPVEKLLKTRLGKDTVQLFEYKPISQGLPPPCPTQLLSPFSSIIPFPTYFPALHKFIFTYQAKKIEDEGQGRELVFQLWQQLEGILSEITPEGLEILLPFILSLMSEENTAVYAAWYLFEPIAKSLGPKNANKYLLKPLIGAYETPCSRHGRFYLYTDCFVAQLIVRLGLQSFILNLLPHILQILVGIESSREESKSLLGAAEDDESGGGSPMSCMFGEEIKMDVEHSSTALDLLDYTSGVSFHDQAYLPESEDFQSGLYVGESLQPQEQESLSLGRLSDKSSASEVSLGEDRPADGDSQKDKSSLKSVDSSQDLKQSEDSEEEEEEREEEERDDTAVDAELVGAVDVGVSVDAGTSVDVTLADDGSEPEDGEGEELPDHSDDKEQTILLDTACKMVRWLSAKLGPTVTSRFIARNLLRLLTSCYIGPTRQQFVPSNDENGPLSTGNIYQKRPVLGDQVSKPVLACLLHVAYLYGEPVLTYQYLPYISYLVAPGSGSGGGRLNSRKEAGLLAAVTLTQKIVVCLSDTTLMDILPKISQEVLLPVLGFLTSLSVGFPSGAQARVVLCIKTISLIALICLRIGQEMVQQHLSDTVRNFFGAFSLLQELQDQGLTAESLSGCEVPVMEVPLREGKLLALDPAVLLELQKVFNPEMAYITYIPFSCLLGDVIRTVVPNHSLVEKLASLYLENVNPKNLQVVGLEQAPSMAGSDQDMRGTEAFSSPQEDSHSGTFGSVLVGNRIQVPVDTQREGLGLLRLSAGTDGFIPSSSSEENTLKHDLPRSTHVLCGNWLAYWQYEIGVSQHDPRFHFHQIKLQSFSGHSGAIKCVAPLSSEDFFLSGSKDKTVRLWPLYNYGDGTSEVPPRFTYSEHKKSVFYVSQLEASQHVVSCDGTVHIWDQFTGKLIRTFDELDSKAPITAVTTMPPPYHSISVASADSVLRFIDHRKPGLQHEFRLAGGVNAGLIRCLAVSPNGRSVMAGFSSGFIVLLDTRTGLIMRGWPAHEGDILQIKAAEGNVLISSSSDHSMTVWKELEQKPLHHYKSASEPIHAFDLYGNEVVTGTVANKIGVYSMLESSALPVSTTKLSSENFRGTLTSLAVLPMKCHLLLGSDNGVIRLLA", "length": 1923, "header": "tr|A0A8V1ACP1-1|A0A8V1ACP1_CHICK Computationally mapped isoform of WD repeat-containing protein 81 OS=Gallus gallus OX=9031 GN=WDR81 PE=1 SV=1 CANONICAL=A0A8V1ANI3-1" }, "locus": { "chromosome": "19", "start_pos": 5879035, "end_pos": 5868780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071069.1", "url": "https://www.ensembl.org/id/ENSGALT00010071069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043760.1", "url": "https://www.ensembl.org/id/ENSGALP00010043760.1" } ] } }, { "isoform_ac": "A0A8V1AI00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3/entry#A0A8V1AI00-1", "sequence": { "sequence": "MCSAARRSRHAPRAVSWHFPEGATMDALLRSVEKDLSINRWQLAAASDGTHVTALVPHKWLANLRERRALPALCPRPEGLSEVEVRTFLQRSVQKLPAGWTRVEIHGLCKERLTWPLRVPPVADPRGGGAETLHGFMQRVASQNYRNLWGRAHCLYVRPYRHAHAPPAVPVLDALRAALQKAYGCPILQVGRSVPSASPAKGISSVPSSCPNVLQAEALLESAEMLYIIYPYVQYCLHDIVTFSPAKLTNSHAKILFLLFHVLQAMRACHQAGLACGAFSLRDVAVDEKLCSRLRVNFREYEGPRKEETNAEADLERVNEQSGAGMRGDVARCYTCQQELRDLVLQWVHGRVSNFDYLMHLNSLAGRRMGDPNYHPVLPWVVDFTTKNGKFRDLRKSKFRLNKGDKQLDFTYEMTKQAFVAGGSSGEQLHVPHHISDVLSDITYYVYTARRTPKSVLCCHVRSQWEPNEYPASMERMQSWTPDECIPEFYTDPSIFRSIHPDMPDLDVPSWCSSYEEFIEVHRMLLESREVSQDLHHWIDLTFGYKLQGKDAVKEKNVCLHLVDNHTHLTTYGVVQLFDQPHPRRMVGPACTPAEAPAIARPLLQNIKETVILEDIPCPVTDAVNGLVLEATPTETTWSGEKPITGEDDLEQGTEALDSISVSSRAPDQPCSSSAQPSTLPAYPTEGKASGVRPLRRSKAGAADQADRDDMKITLPEGFNPLQALEELEKLDNFLVKGLSSDMQLMEQPGEEPLLGLSDLFQRDMQALGILIAEIIFAPRIRPSKPDASLLERFLMVRNLCRYHPKEIPAPLQHVLHILLQLSVPVEKLLKTRLGKDTVQLFEYKPISQGLPPPCPTQLLSPFSSIIPFPTYFPALHKFIFTYQAKKIEDEGQGRELVFQLWQQLEGILSEITPEGLEILLPFILSLMSEENTAVYAAWYLFEPIAKSLGPKNANKYLLKPLIGAYETPCSRHGRFYLYTDCFVAQLIVRLGLQSFILNLLPHILQILVGIESSREESKSLLGAAEDDESGGGSPMSCMFGEEIKMDVEHSSTALDLLDYTSGVSFHDQAYLPESEDFQSGLYVGESLQPQEQESLSLGRLSDKSSASEVSLGEDRPADGDSQKDKSSLKSVDSSQDLKQSEDSEEEEEEREEEERDDTAVDAELVGAVDVGVSVDAGTSVDVTLADDGSEPEDGEGEELPDHSDDKEQTILLDTACKMVRWLSAKLGPTVTSRFIARNLLRLLTSCYIGPTRQQFVPSNDENGPLSTGNIYQKRPVLGDQVSKPVLACLLHVAYLYGEPVLTYQYLPYISYLVAPGSGSGGGRLNSRKEAGLLAAVTLTQKIVVCLSDTTLMDILPKISQEVLLPVLGFLTSLSVGFPSGAQARVVLCIKTISLIALICLRIGQEMVQQHLSDTVRNFFGAFSLLQELQDQGLTAESLSGCEVPVMEVPLREGKLLALDPAVLLELQKVFNPEMAYITYIPFSCLLGDVIRTVVPNHSLVEKLASLYLENVNPKNLQVVGLEQAPSMAGSDQDMRGTEAFSSPQEDSHSGTFGSVLVGNRIQVPVDTQREGLGLLRLSAGTDGFIPSSSSEENTLKHDLPRSTHVLCGNWLAYWQYEIGVSQHDPRFHFHQIKLQSFSGHSGAIKCVAPLSSEDFFLSGSKDKTVRLWPLYNYGDGTSEVPPRFTYSEHKKSVFYVSQLEASQHVVSCDGTVHIWDQFTGKLIRTFDELDSKAPITAVTTMPPPYHSISVASADSVLRFIDHRKPGLQHEFRLAGGVNAGLIRCLAVSPNGRSVMAGFSSGFIVLLDTRTGLIMRGWPAHEGDILQIKAAEGNVLISSSSDHSMTVWKELEQKPLHHYKSASEPIHAFDLYGNEVVTGTVANKIGVYSMLESSALPVSTTKLSSENFRGTLTSLAVLPMKCHLLLGSDNGVIRLLA", "length": 1937, "header": "tr|A0A8V1AI00-1|A0A8V1ANI3_CHICK Computationally mapped isoform of WD repeat-containing protein 81 OS=Gallus gallus OX=9031 GN=WDR81 PE=1 SV=1 CANONICAL=A0A8V1ANI3-1" }, "locus": { "chromosome": "19", "start_pos": 5879035, "end_pos": 5867606, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071071.1", "url": "https://www.ensembl.org/id/ENSGALT00010071071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043762.1", "url": "https://www.ensembl.org/id/ENSGALP00010043762.1" } ] } }, { "isoform_ac": "A0A8V1ANI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3/entry#A0A8V1ANI3-1", "sequence": { "sequence": "MPAVGCPQQPRTQGGSGAAGTCPARGHRDRGATMDALLRSVEKDLSINRWQLAAASDGTHVTALVPHKWLANLRERRALPALCPRPEGLSEVEVRTFLQRSVQKLPAGWTRVEIHGLCKERLTWPLRVPPVADPRGGGAETLHGFMQRVASQNYRNLWGRAHCLYVRPYRHAHAPPAVPVLDALRAALQKAYGCPILQVGRSVPSASPAKGISSVPSSCPNVLQAEALLESAEMLYIIYPYVQYCLHDIVTFSPAKLTNSHAKILFLLFHVLQAMRACHQAGLACGAFSLRDVAVDEKLCSRLRVNFREYEGPRKEETNAEADLERVNEQSGAGMRGDVARCYTCQQELRDLVLQWVHGRVSNFDYLMHLNSLAGRRMGDPNYHPVLPWVVDFTTKNGKFRDLRKSKFRLNKGDKQLDFTYEMTKQAFVAGGSSGEQLHVPHHISDVLSDITYYVYTARRTPKSVLCCHVRSQWEPNEYPASMERMQSWTPDECIPEFYTDPSIFRSIHPDMPDLDVPSWCSSYEEFIEVHRMLLESREVSQDLHHWIDLTFGYKLQGKDAVKEKNVCLHLVDNHTHLTTYGVVQLFDQPHPRRMVGPACTPAEAPAIARPLLQNIKETVILEDIPCPVTDAVNGLVLEATPTETTWSGEKPITGEDDLEQGTEALDSISVSSRAPDQPCSSSAQPSTLPAYPTEGKASGVRPLRRSKAGAADQADRDDMKITLPEGFNPLQALEELEKLDNFLVKGLSSDMQLMEQPGEEPLLGLSDLFQRDMQALGILIAEIIFAPRIRPSKPDASLLERFLMVRNLCRYHPKEIPAPLQHVLHILLQLSVPVEKLLKTRLGKDTVQLFEYKPISQGLPPPCPTQLLSPFSSIIPFPTYFPALHKFIFTYQAKKIEDEGQGRELVFQLWQQLEGILSEITPEGLEILLPFILSLMSEENTAVYAAWYLFEPIAKSLGPKNANKYLLKPLIGAYETPCSRHGRFYLYTDCFVAQLIVRLGLQSFILNLLPHILQILVGIESSREESKSLLGAAEDDESGGGSPMSCMFGEEIKMDVEHSSTALDLLDYTSGVSFHDQAYLPESEDFQSGLYVGESLQPQEQESLSLGRLSDKSSASEVSLGEDRPADGDSQKDKSSLKSVDSSQDLKQSEDSEEEEEEREEEERDDTAVDAELVGAVDVGVSVDAGTSVDVTLADDGSEPEDGEGEELPDHSDDKEQTILLDTACKMVRWLSAKLGPTVTSRFIARNLLRLLTSCYIGPTRQQFVPSNDENGPLSTGNIYQKRPVLGDQVSKPVLACLLHVAYLYGEPVLTYQYLPYISYLVAPGSGSGGGRLNSRKEAGLLAAVTLTQKIVVCLSDTTLMDILPKISQEVLLPVLGFLTSLSVGFPSGAQARVVLCIKTISLIALICLRIGQEMVQQHLSDTVRNFFGAFSLLQELQDQGLTAESLSGCEVPVMEVPLREGKLLALDPAVLLELQKVFNPEMAYITYIPFSCLLGDVIRTVVPNHSLVEKLASLYLENVNPKNLQVVGLEQAPSMAGSDQDMRGTEAFSSPQEDSHSGTFGSVLVGNRIQVPVDTQREGLGLLRLSAGTDGFIPSSSSEENTLKHDLPRSTHVLCGNWLAYWQYEIGVSQHDPRFHFHQIKLQSFSGHSGAIKCVAPLSSEDFFLSGSKDKTVRLWPLYNYGDGTSEVPPRFTYSEHKKSVFYVSQLEASQHVVSCDGTVHIWDQFTGKLIRTFDELDSKAPITAVTTMPPPYHSISVASADSVLRFIDHRKPGLQHEFRLAGGVNAGLIRCLAVSPNGRSVMAGFSSGFIVLLDTRTGLIMRGWPAHEGDILQIKAAEGNVLISSSSDHSMTVWKELEQKPLHHYKSASEPIHAFDLYGNEVVTGTVANKIGVYSMLESSALPVSTTKLSSENFRGTLTSLAVLPMKCHLLLGSDNGVIRLLA", "length": 1946, "header": "tr|A0A8V1ANI3-1|A0A8V1ANI3_CHICK Isoform 1 of WD repeat-containing protein 81 OS=Gallus gallus OX=9031 GN=WDR81 PE=1 SV=1 CANONICAL=A0A8V1ANI3-1" }, "locus": { "chromosome": "19", "start_pos": 5879035, "end_pos": 5868181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071070.1", "url": "https://www.ensembl.org/id/ENSGALT00010071070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043761.1", "url": "https://www.ensembl.org/id/ENSGALP00010043761.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1261, "start_aa": "Thr", "end_pos": 1261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1261", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417560", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417560", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3S5ZPK5-1", "protein_name": "WD repeat-containing protein 81", "gene_name": "WDR81", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALRSRGREVALTAKAEDWSPPPSPDMEELLRSVERDLNIDARQLAPAPGGAHVVALVPARWLASLRERRLPLGPCPRAEGLSEAEVRTFLQRSVQRLPAGWTRVEVHGLRKRRLSYALGGLPFEEGSSTPETLTRFMQDVAAQNYRNLWRHAYHTYGQPYSHSPAPAAVPALDSVRQALQRVYGCPFLPLGEAAQCPSYAREGPCAPRGCPASPSLLRAEALLESPEMLYVVYPYVQFSLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHHQGLACGALSLHHIAVDEKLCSELRLDLSAYERPEEAGDEETPEARNGAGVEPGEEGRRGPGCPTCQEELRGLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVVDFTAPRGRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASMERMQSWTPDECIPEFYTDPSIFCSIHPDMPDLDVPAWCCSNQEFVAAHRALLESREVSQDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLTSYGVVQLFDQPHPQRLAGAPALAPEPPLVPRLWFHTIQESTGREDFPAQLTNGMGRTVLEATPCEAGWARDRPGVGEDELEQATEALDSISLAGKTGDQLGPSPSSTSSSSQVPPGLLPFSGASASRPGRRNRAAGTDPREGEEGKILLPEGFSPLQALEELEKLGNFLTKGLGGRLEVPEQPWVQPPVQLRDLFHRDMQALGVLLAEMVFATRVRTLQPDAPLWVRFKAVQGLCARHPKEVPVSLQPVLDTLLQLSGPQGPVVAGRGKLDPLFTYRPVSQGLPPPCPAQLLSPFSSVVPFPPYFPALHKFILLYQVRRVEDEAQGRELVFALWQQLGAVLSDITPEGLEILLPFVLSLMSEEHTAVYAAWYLFEPVAKALGPKNANKYLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLVHLLPHVLQVLAGVEASQEENKGLAGAAEDEESGLLGSGPGSCAFEEEIHMEREPAAASGLGLPDYTSGVSFHDQADLPETEDFQAGLYVAESPQPQEAEAVSLGRLSDKSSTSEASLGEERVADEGGVPVDKSSLRSGDSSQDLKQSEGSEEDEEEEEEGCVVLEVGEGEGEQEEVPETSELMLSDTVLSMDTVVAGDAGANGEEEEEPLTEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTGSNGESPPLSVGNIYQKRPILGDIVSAPVLSCLLHIAHLYGEPVLTYQYLPYISYLVAPGSTSGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLTSLVTGFPSGAQARTVLCMKTISLIALICLRIGQEMVQQHLSEPVATFFRVFSQLHELRHQDLKLESVGRSSEGQLPEVAFSDGQLRPADPALLDELQKVFTLEMAYTIYVPFSCLLGDIIRKIVPNHELVGELAGLYLDSISPSSRSPAIVEPTAPSTGPEWDPQGGGCPQDDSHSGTFGSVLVGNRIQIPNDSQPDSPGPLGPISGVGGGEPGSQSEDNALKRELPRSAHGLSGNWLAYWQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVVPLSGEDFFLSGSKDHTVRLWPLYNSGDGTSETAPRLVYAQHRKSVFFVGQLEAPQCVVSCDGAVHVWDPFTGKTLRTVEPSDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLSSGLNPGLVRSLAVSPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSILVSSSSDHSLTVWKELEPKPTHHYKSASDPIHTFDLYGSEVVTGTVANKIGVCSLLEPPSQATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGVVRLLA", "length": 1948 }, "evidence": [ { "id": "A0A8V1ANI3", "url": "https://omabrowser.org/oma/group/A0A8V1ANI3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A9J7GD94-1", "protein_name": "WD repeat-containing protein 81", "gene_name": "Wdr81", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQGSRGRKVVLTAGSEGWSPSPGPDMEELLRSVERDLNIDVRQLAPAPGGTHVVALVPARWLACLRERRLGPCPRAEGLGEAEVRTLLQRSVQRLPPGWTRVEVHGLRKRRLSYPLGGVLPFDEGSCNPETLTRFMQEVAAQNYRNLWRHAYRTYGQPYSHSTAPSAVPALDSIRQALQRVYGCTFLPVGESIQCPSNVRDGPSPSRGSPTCPSLLRAEALLESPEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLHHIAVDEKLCSELRLDLSAYEMPSEDENQEVSVEKNRTGVKSEKEEAGRPACPTCRKELKGLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPYGRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPATMERMQTWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSNQEFVAAHRALLESWEVSQDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLTSYGVVQLFDQPHPQRLAGAPALAPEPPLIPRLLVQPIQEATGQEDIPGQLINGVGRLVLEATPCETGWTRDRPMTGEDDLEQATEALDSISLPGKAGDQLGSSSSQASPSLLSFSATSGSRPGRRSKAGGSDPGEGEEGKIALPEGFSPIQALEELEKMGNFLAKGLGSQLEVPEQPQVQPPVHLQNLFHRDMQVLGVLLAEMVFATRVRTLQPDAPLWVRFEAVRGLCTRHSKDIPVSLQPVLDTLLQLSGPKSPTVVKKGKLDPLFEYRPVSQGLPPPSPAQLLSPFSSVVPFPPYFPALHKFILLYQARRVEDEAQGRELVFALWQQLGAVLNDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNTNKYLLKPLIGAYESPCRLHGRFYLYTDCFVAQLVVRLGLQAFLIHLLPHVLQVLAGVEASQEESKGLVGTTEDEESELPGPGPGSCAFGEEIQMDGEPAASSGLGLPDYRSGVSFHDQADLPDTEDFQSGLYVAESPQPQEAEAVSLGQLSDKSSTSETSQGEERGGDDGGAPVDKNSLKSGDSSQDLKQSEGSEEEEEEEGCVILEEEEETDDVTGTSELALSDTMLSMETVVAPGDGRDREEEEEPLTEQTEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSSDESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIAHLYGEPVLTYQYLPYISYLVAPGSNSSPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLTSLVTGFPSGAQARTVLCVKTVSLIALICLRIGQEMVQQHLSEPVAAFFQVFSHLHELGQQDLQLDPKGCPEGQLPEATFSDGHRRPVDPTVLEELQKVFTLEMAYTIYVPFSCLLGIAHHVPLHSVGDIIQKIIPNHELVGELAGLYLESISPSARNPASMEPTVPSAGPDWDPQSGSCLQDDGHSGTFGSVLVGNRIQIPESQPESPGLLGPISGVGGGGLSSRSEDNALKRELPRSAHGLSGNWLAYWQYEIGVSQQDAHFHFHQIRLQSFLGHTGAVKCVAALSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLIYAQHRKSVFYVGQLEAPQYVVSCDGAVHVWDPFTGKTLRTVDPSDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRSLAVSPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAIEGSMLVSSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVITGTVANKIGICSLLEPPSQATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGIIRLLA", "length": 1945 }, "evidence": [ { "id": "A0A8V1ANI3", "url": "https://omabrowser.org/oma/group/A0A8V1ANI3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A929-1", "protein_name": "WD repeat-containing protein 81", "gene_name": "Wdr81", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQGSRRRKVVLTAGAEGCSSSSGPDMEELLRCAERDLNIDARQLALAPGGTHVVALVSTRWLASLRERRLGPCPRAEGLGEAEVRTLLQRSVQRLPQGWTRVEVHGLRKRRLSYPLSRVLPFEEGSCSPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSTAPSAIPALDSIRQALQRVYGCTFLPVGESMQCLSNVRDGPSRGSSACPSLLRAEALLESPEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLHHIAVDEKLCSELRLDLSAYEMPSEDENQEVSEEKDRTGVKSEKDGEGRPGCPTCQKELRGLVLDWVHGRVSNFYYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPYGRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGSGEPLHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPATMERMQTWTPDECIPEFYTDPSIFCSIHPDMPDLDVPAWCSSNQEFVTAHRALLESWEVSQDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLTSYGVVQLFDQPHPQRLAGAPALAPEPPLIPRLLVQPIQEATGQEDISGQLINGAGRHVVEVTPCESGWTRERPTAGEDDLEQATEALDSISIPGKAGDQPGSSSSQASPGLLPFSAPSGSRPGRRSKATGLDSGEGDEGKIVLPEGFSPIQALEELEKVGNFLARGLGSQLEEPEKPQAQPPVYLQSLFHRDMQVLGVLLAEMVFATRVRILQPDAPLWVRFEAVRGLCTRHSKDIPVSLQPVLDTLLQLSGPKSPLVVKKGKLDPLFEYRPVSQGLPPPSPAQLLSPFSSVVPFPTYFPALHKFILLYQARRVEDEVQGRELVFALWQQLGAVLNEITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNTIKYLLKPLIGAYENPCRLHGRFYLYTDCFVAQLVVRLGLQAFLIHLLPHVLQVLAGVEASQEEGKGLVGTTEDEENELPVPGPGSCAFGEEIQMGGQPAASSGLGLPDYRSGVSFHDQADLPDTEDFQAGLYVAESPQPQEAEAVSLGQLSDKSSTSEASQGEERGGDDGGAPVDKNSVKSGDSSQDLKQSEGSEEEEEEEEGCVVLEEEEQDEVTGTSELTLSDTILSMETVVAPGDGRDREEEEEPLPEQTEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSCDDSPPLNAGNIYQKRPVLGDIVSGPVLSCLLHIAHLYGEPVLTYQYLPYISYLVAPGSNSSPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLTSFVTGFPSGAQARTVLCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSHLHELRQQDLQLDLKGCTEGQLPEATFSDGQRRPVDPTLLEELQKVFTLEMAYTIYVPFSCLLGDIIRKIIPNHELVGELAGLYLESMSPSSLRNPASMEPVTPSAGPEWNPQSGSCLQDDGHSGTFGSVLVGNRIQIPDSQPQSSGPLGSISGVGSGGLSSRNEDNALKRELPRSAHGLSGNWLAYWQYEIGVSQQDAHFHFHQIRLQSFPGHTGAVKCVAALSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLIYAQHRKSVFYVGQLEAPQYVVSCDGAVHVWDPFTGKTLRTVDPSDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRSLAVSPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVIVSSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVVTGTVANKIGVCSLLEPPSQATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGIIRLLA", "length": 1933 }, "evidence": [ { "id": "A0A8V1ANI3", "url": "https://omabrowser.org/oma/group/A0A8V1ANI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FEV0-1", "protein_name": "WD repeat-containing protein 81", "gene_name": "wdr81", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEWLAPALERDLGIDQRQTAHSQRPNELVVLVPTRWVMALRNKRVTRCAKYESFSEGEICTLLQRSQMKLPSGWTRVCIQGLRKRKLGYRFARETGCHGEGLSQDSFMTLMQGVSQSNFRNLWHEAYMTHVQPYADSVEQTPVLALDAVRQALQKLFCSNFISTDRVSPSLSPAKEKEKDCPFLSTCSAPKQSTESLCPNVLPAECLLESEEVLYVVFPYTQYTVHDIVTYSPAKLANSNAKILFILYQLLIAMRECHASGLLCGELSLLDIAVDEQLCSRLKISLAHYEKFKEYRDAVPYALQNKVPMSVSTKDNHNNGVSGQLCRNCQDELKSLVLDWVNGQVSNFQYLMELNRLAGRREGDPNYHPVLPWVVDFTVPYGRFRDLKKSKFRLNKGDKQLDFTYEMTKEALAAVSGSGGSNYPPDLGGPVVPGGPGQSDHLHVPHHISDVLSDITYYVYKARQTPKSVLCSHVRSQWEPNEYPASMERIQSWTPDECIPEFYRDPSIFRSIHPDMPDLDVPPWCNSYEEFIAVHRQLLESREVSQQLHHWIDLTFGYKLSGKEAIKAKNVCLHLVDNHTHLTSYGVVQLFDHPHPPRLALYQYAPPEPPHFGRVNVTTWQIPPLETTMDGVDGLVPEATGCESSGWSVVGRDEELEQAIEALDLSGSSSSTSASVSIPVVGSAAGKTSGETIGLVVSPSHGSFPGEATGNVTNTLGSGIRTAMLHRAASVSKKPEASNLEDFKISLPDGFKPLQPLEELEKLNTFLVKGLHSEIEHTMDLGINKKDLRSVPKVPLSFTDLFQRDMQALGVLIAEIFYSSKLRGLRPETHLRDRFQAVLKLCSTNLRDVPLPLHHALDTLLQVHKHCLKTETIIMHPQGLPFLFKYDPICEGLPPPNPWQLLSPIVSPLPFPEYFPTLHKFIFSYHSKMESINNIQGRDIVFNLWQQLETLLKGDITTEGLEILLPFVLSLMSEESTAVYAAWYLFEPVSRVLGPRNASKYLIKPLVGVYENPRCLRGRFYLYTDCFVLQLIVRLGLQVFLSSLLPHVLQVMTGFESCNTAAGTEWEGMKVLRGAAGALDEEEEEYECDDRRSSNATSSGKVGGGSGGGSGGVGVVGDQGLVDYSSGISLNDQVFLNEGEDFQNGFYVNNSASGATTVGTKQQNQSTANKDQDQESLSVGKLSDKSSASEVSIGDRASLKSADSSQDLKQASDGEDGGELEDEEETVEDREITVQRVPSLEMTLSVCTEESEATVATLEGDVMNGIVQEDGEKNMEEEETEHDPLEDSEEKEHKILLDTVCKTVRWLSAKLGPTLTSRFIARNLLRLLTSCYIGLDKHQFMLSVNEENSLECVGSVYEKKPVVGDQTARPVLECLIYIAHLYGEPVLTYQYLPYIGYLVSPPSSCRLNTRKEAGLLGAVVLTQKIIVFLSDTTLMDMLMKINQEVLLPLLDLLTSTKMGFPSGVQTRSAVCLKTLSLMALICLRIGREMVQQHMAETLSRFFQVFSLLQFLQNQIGSAPRREVAECTYLDLRIPDGAELTIELGVLEELQAVFNPEMAYASYIPFYCLIGDSGIRKLVTNHELVWSLAQSYHERASPGSPESNPVGGQRASAVGLSPSMGRQMSRSPFPAPSSTSTPLGGDILPESGTFGSHLVGNRIQVTRDTEACGSPNLSSLETWTHGRPYGSNAPPMSLATTALSSAGPSFSHSSYSWVMGPTPEDSALKQDLPRSSRSLQGNWLAYWQYEIGLNQQDSHFHFHQIRLQSFIGHSGTAKCLAPLAGEDYFLSGSKDKTVRLWPLYNHGDGTREVEPRLTYTEHRKSIFYVGQLEALQEVVSCDGTVHLWDQFTGKNIRCNEPLDGKNPITAVTTMPAPHCSVVFASADSVLRFIDPRKPGLQHEFRLAYSNLSAGLIRCLAVSPGGRTIAAGFSTGFIVLLDARTGLVLRGWPGHEGDILQMKAAEGNLLVSSSSDHTLTVWKDVEHKPLHQYRTPSDPIHAFDLYGAEIVAGTVANKIGVYSILDSTASLAGSTKLSTENFRGTLTSLSVLPTKRLLLLGSDNGAIRLLA", "length": 2065 }, "evidence": [ { "id": "A0A8V1ANI3", "url": "https://omabrowser.org/oma/group/A0A8V1ANI3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q562E7-1", "protein_name": "WD repeat-containing protein 81", "gene_name": "WDR81", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALVPARWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEVHGLRKRRLSYPLGGGLPFEDGSCGPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSPAPSAVPALDSVRQALQRVYGCSFLPVGETTQCPSYAREGPCPPRGSPACPSLLRAEALLESPEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFILFRVLRAMDACHRQGLACGALSLYHIAVDEKLCSELRLDLSAYERPEEDENEEAPVARDEAGIVSQEEQGGQPGQPTGQEELRSLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPHGRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGGGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPASMERMQNWTPDECIPEFYTDPSIFRSIHPDMPDLDVPAWCSSSQEFVAAHRALLESREVSRDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLASYGVVQLFDQPHPQRLAGAPALAPEPPLIPKLLVQTIQETTGREDFTENPGQLPNGVGRPVLEATPCEASWTRDRPVAGEDDLEQATEALDSISLAGKAGDQLGSSSQASPGLLSFSVASASRPGRRNKAAGADPGEGEEGRILLPEGFNPMQALEELEKTGNFLAKGLGGLLEVPEQPRVQPAVPLQCLLHRDMQALGVLLAEMVFATRVRTLQPDAPLWVRFQAVRGLCTRHPKEVPVSLQPVLDTLLQMSGPEVPMGAERGKLDQLFEYRPVSQGLPPPCPSQLLSPFSSVVPFPPYFPALHRFILLYQARRVEDEAQGRELVFALWQQLGAVLKDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANKYLLKPLIGAYESPCQLHGRFYLYTDCFVAQLMVRLGLQAFLTHLLPHVLQVLAGAEASQEESKDLAGAAEEEESGLPGAGPGSCAFGEEIPMDGEPPASSGLGLPDYTSGVSFHDQADLPETEDFQAGLYVTESPQPQEAEAVSLGRLSDKSSTSETSLGEERAPDEGGAPVDKSSLRSGDSSQDLKQSEGSEEEEEEEDSCVVLEEEEGEQEEVTGASELTLSDTVLSMETVVAGGSGGDGEEEEEALPEQSEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSSGESPPLSAGNIYQKRPVLGDIVSGPVLSCLLHIARLYGEPVLTYQYLPYISYLVAPGSASGPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLTSLVTGFPSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQLHELRQQDLKLDPAGRGEGQLPQVVFSDGQQRPVDPALLDELQKVFTLEMAYTIYVPFSCLLGDIIRKIIPNHELVGELAALYLESISPSSRNPASVEPTMPGTGPEWDPHGGGCPQDDGHSGTFGSVLVGNRIQIPNDSRPENPGPLGPISGVGGGGLGSGSDDNALKQELPRSVHGLSGNWLAYWQYEIGVSQQDAHFHFHQIRLQSFPGHSGAVKCVAPLSSEDFFLSGSKDRTVRLWPLYNYGDGTSETAPRLVYTQHRKSVFFVGQLEAPQHVVSCDGAVHVWDPFTGKTLRTVEPLDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRALAISPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLVSSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVVTGTVSNKIGVCSLLEPPSQATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGVIRLLA", "length": 1941 }, "evidence": [ { "id": "A0A8V1ANI3", "url": "https://omabrowser.org/oma/group/A0A8V1ANI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5ND34-1", "protein_name": "WD repeat-containing protein 81", "gene_name": "Wdr81", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQGSRRRKVVLTAGSEGWSPSSGPDMEELLRSVERDLNIDARQLALAPGGTHVVALVSTRWLASLRERRLGPCPRAEGLGEAEVRTLLQRSVQRLPPGWTRVEVHGLRKRRLSYPLGGGVPFEEGSCSPETLTRFMQEVAAQNYRNLWRHAYHTYGQPYSHSTAPSALPALDSIRQALQRVYGCTFLPVGESIPCLSNVRDGPCPSRGSPACPSLLRAEALLESPEMLYVVHPYVQFSLHDVVTFSPAKLTNSQAKVLFLLFRVLRAMDACHRQGLACGALSLHHIAVDEKLCSELRLDLSAYEMPSEDENQEGSEEKNGTGIKSEKEGEGRTECPTCQKELRGLVLDWVHGRISNFHYLMQLNRLAGRRQGDPNYHPVLPWVVDFTTPYGRFRDLRKSKFRLNKGDKQLDFTYEMTRQAFVAGGAGSGEPPHVPHHISDVLSDITYYVYKARRTPRSVLCGHVRAQWEPHEYPATMERMQTWTPDECIPEFYTDPSIFCSIHPDMPDLDVPAWCSSNQEFVAAHRALLESWEVSQDLHHWIDLTFGYKLQGKEAVKEKNVCLHLVDAHTHLTSYGVVQLFDQPHPQRLAGSPALAPEPPLIPRLLVQPIREATGQEDISGQLINGAGRLVVEATPCETGWTRDRPGTGEDDLEQATEALDSISLPGKAGDQPGSSSSQASPGLLSFSAPSGSRPGRRSKAAGLDPGEGEEGKIVLPEGFSPIQALEELEKVGNFLAKGLGSQLEEPEKPHAQPPVHLQSLFHRDMQVLGVLLAEMVFATRVRILQPDAPLWVRFEAVRGLCIRHSKDIPVSLQPVLDTLLQLSGPKSPMVSKKGKLDPLFEYRPVSQGLPPPSPAQLLSPFSSVVPFPPYFPALHKFILLYQARRVEDEVQGRELAFALWQQLGAVLNDITPEGLEILLPFVLSLMSEEHTAVYTAWYLFEPVAKALGPKNANKYLLKPLIGAYESPCRLHGRFYLYTDCFVAQLVVRLGLQAFLTHLLPHVLQVLAGVEASQEEGKGLVGTTEDEESELPVSGPGSCAFGEEIQMDGQPAASSGLGLPDYRSGVSFHDQADLPDTEDFQAGLYVAESPQPQEAEAVSLGQLSDKSSTSEASQGEERGGDDGGAPADKNSVKSGDSSQDLKQSEGSEEEEEEEGCVVLEEDQEDEVTGTSELTLSDTMLSMETVVAPGDGRDREEEEEPLTEQTEGKEQKILLDTACKMVRWLSAKLGPTVASRHVARNLLRLLTSCYVGPTRQQFTVSSDDTPPLNAGNIYQKRPVLGDIVSGPVLSCLLHIAYLYGEPVLTYQYLPYISYLVAPGSNSNPSRLNSRKEAGLLAAVTLTQKIIVYLSDTTLMDILPRISHEVLLPVLGFLTSFVTGFPSGAQARTVLCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSHLHELRQQDLPLDPKGCTEGQLPEATFSDGQRRPVDPTLLEELQKVFTLEMAYTIYVPFSCLLGDIIRKIIPNHELVGELAGLYLESMSPSSRNPASMEPTMASAGPEWDPQSGSCLQDDGHSGTFGSVLVGNRIQIPDSQPQSPGPLGSLSGVGSSGGLSNRNEDNALKRELPRSAHGLSGNWLAYWQYEIGVSQQDAHFHFHQIRLQSFPGHTGAVKCVAALSSEDFFLSGSKDRTVRLWPLYNYGDGTNETASRLIYAQHRKSVFYVGQLEAPQYVVSCDGAVHVWDPFTGKTLRTVDPSDSRVPLTAVAVMPAPHTSITMASSDSTLRFVDCRKPGLQHEFRLGGGLNPGLVRSLAVSPSGRSVVAGFSSGFMVLLDTRTGLVLRGWPAHEGDILQIKAVEGSVLISSSSDHSLTVWKELEQKPTHHYKSASDPIHTFDLYGSEVVTGTVANKIGVCSLLEPPSQATTKLSSENFRGTLTSLALLPTKRHLLLGSDNGIIRLLA", "length": 1934 }, "evidence": [ { "id": "A0A8V1ANI3", "url": "https://omabrowser.org/oma/group/A0A8V1ANI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKD0-1", "protein_name": "WD repeat domain 81", "gene_name": "Wdr81", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDSEQIWPEIGVDPQHVCEAGGDGRFQVICDKAWLQSLERNRRLTHFPSWPLLDRRSYPIGQLEHPWTRILVQTYRKQPQSRVYPLPRISGDAPSSELPLSYSQAVSFVAHSNFKQLWEEAYRKYNGAHVRMCRSTPSAPSTKPPSGQGQLQPHDVVLKELIQRVYRCPVLHCQLDRDGVSDSSNATSCSAGSCHANVLPALVAIETSTHISVFFYPPALECSLYDCITFSPALLGKNYNKTLFVIYQILQLAKHLQGQGLFLGDLRLQDIVLRENLWLQVLPRLQCNLLDDDPAGEDMSPLTPLVSEDLGEAREAQQALPSSSTMFDLRFAYDPAHFNLREYTEMWCNGQLSNFDYLTILNNACGRSLTNAAYHHIMPWVTDFSGRGGGAWRDLTKSKYRLNKGDVHLDLMYAHASQHGSADGSYQAIGDQAPHHVSDFLSEITYFVYMARRTPQSILCAHVRPIWVPAEYPVSIQRLQEWTPDECIPEFYSDPMIFKSIHEDLPDLELPAWATCPEDFICKHREALESQYVSERLHHWIDLNFGYKLSGKAAVKSKNVCLTLVDQHRNLSQRGIVQLFASAHPPRRYATPWFSRTAPRLSQLYASPAKRLAKSTENLQAESATGSSHLSLRLGDDGSSGSVHSSSASASASNFYAITNFIELPENYNPALLLHNLETLEAFYARTFPQQRASANPEEKMISSDLMFEQNSAEHSFTNQLFASGDELPPKSKNLLREKRNCLQHLLNVRKERDLHVLGCLIIELFAMQRLRPLLMGNGLTATFDSRLSACRTVAQLHRQELPKPVRRVVRLLLQLEQPGEEDQGLPQPPNPAQLLEPMFSNLLLPFPSHYMAVYALVRSLHAFEANAVLLELQTHFSCKGGRECERYTEMDRQRVLFERKIAECKVMSCCAHVKRLLEPMSFAYEQFTPVELLLPHIIDLLRDERTSILTAWNLFDPIAQALGVSQTQQHLLQPLLKLYDVESVSSPDDGGSNGSTNSGGHLRFSASSSFKSRKSVKLYHHSFLLRLIVRFGLRCFLHHFIAPLIEAVGGYKEPEQGNGYHYHSGGSRRTSKNLNFASENEVHQTEVAPEMKPDIEELFTFEDDHDRASTQDSKSIDSFDMRPSTSAASAEEARESDGSPDKLVINELIYGARISPDKLSLKESQTPPALVPPPIGPRSPTIEIPMGPTAGGIRRSFQLSAIDCDIGSRKSVDSFDLISQAVEQLPPPAEESEAEASDSLQASVISRLSEAKAVQNNRISEMSAESLVWLSHRLGPVLTSRFITRNLLKLLSLCYVGQENLLPEVDDGGSSFNSSPDAANLNYFSIANARVVGDRSAARVLECLMSIAALYGENFLLLQYFPHISELISLCSKRITGSLEGAIISSLQLLKYMVPCLTDASIMEHLQHIMLDAILLPILRLLSSTNLVMPSGYLGRSLLARKFLDAIYALSVRLGSDMTREHLCQPLLNPFFLIFNKAFGLPNDFACDLANLSLVGGASQPERALEELRDVFGPELAHTAYLTFLRFLGEANMKRTLSNLDFVLTLCHEHEQPNGQSKIQLATNVSSGQDVDSVDASCELAANSFGTQIVGNRLQVARNNVELIDMVAYKLDQMPKTRHLKGNWLAYWRNETTRNEKDTQTLNLKQIRLQSFVGHTNSVRAIYALDNENSFISASKDKTVKLWSLRSEGDGRKTSACQFTYTAHKKSINSLGFLESLRYVVSCDSGIHLWDPFIGRPLSVLDAPRHSAVTVVKCLPSHSPLVIAGTAESTVKMVDARSCEYVNEWRVCNASLPNATVRCLAVAPSGNWLAAGLSSGCIVQLDTRTGMVINSWRPMECDLLQLAAPSDQFLVSSALDHSLAVWHALDGIMHYQLKPPPEPAHFLQSVGPSLVYATTGNRVGVYADVAHSHAFSTITKLRSETFRGVLTSLAVLPLNRAFLAGNESGNIALLC", "length": 1953 }, "evidence": [ { "id": "A0A8V1ANI3", "url": "https://omabrowser.org/oma/group/A0A8V1ANI3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "early endosome to late endosome transport", "id": "GO:0045022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "aggrephagy", "id": "GO:0035973", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035973", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase regulator activity", "id": "GO:0035014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase inhibitor activity", "id": "GO:0141039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1506, "end_pos": 1508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI3" }, { "id": "PS50197", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50197" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BEACH", "eco_id": "ECO_0000259", "start_pos": 341, "end_pos": 618, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1261 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1506, "end_pos": 1508 }, { "start_pos": 574, "end_pos": 576 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM05-1", "uniprot_ac": "A0A8V1AM05", "uniprot_id": "A0A8V1AM05_CHICK", "mass": { "chemical_mass": 88481.0, "monoisotopic_mass": 88481.0 }, "refseq": { "ac": "NP_001025886", "name": "protein-lysine N-methyltransferase SMYD4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025886" }, "gene_names": [ { "name": "SMYD4", "type": "recommended", "evidence": [ { "id": "A0A8V1AM05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ] }, { "name": "SMYD4", "type": "synonym", "evidence": [ { "id": "NP_001025886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025886" } ] } ], "protein_names": [ { "name": "Protein-lysine N-methyltransferase SMYD4", "type": "recommended", "evidence": [ { "id": "A0A8V1AM05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05/entry#names_and_taxonomy" } ] }, { "name": "SET and MYND domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "NP_001025886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025886" }, { "id": "A0A8V1AM05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05/entry#names_and_taxonomy" } ] }, { "name": "protein-lysine N-methyltransferase SMYD4", "type": "synonym", "evidence": [ { "id": "NP_001025886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025886" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.223661.1, SRR13267660.1562.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1. On Sep 23, 2021 this sequence version replaced NP_001025886.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001025886", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025886" } ] }, { "annotation": "Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity. May also act as a histone methyltransferase. Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ACR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR3#function" }, { "database": "UniProtKB", "id": "ARBA00093423", "url": "https://www.uniprot.org/uniprotkb/ARBA00093423#function" }, { "database": "UniProtKB", "id": "A0A8V1AI18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI18#function" }, { "database": "UniProtKB", "id": "A0A8V1AK08", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK08#function" }, { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMYD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05", "locus": { "chromosome": "19", "start_pos": 5899669, "end_pos": 5906309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029389", "url": "https://www.ensembl.org/id/ENSGALG00010029389" } ] } } ], "crossref": [ { "id": "A0A8V1AM05", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM05", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417562", "url": "https://www.ncbi.nlm.nih.gov/gene/417562", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417562", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FDCTCPA", "url": "https://omabrowser.org/oma/group/FDCTCPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM05", "url": "https://www.orthodb.org/?gene=A0A8V1AM05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46165:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46165:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025886", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025886", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "51736", "url": "https://www.rhea-db.org/rhea/51736", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ACR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AI18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AI18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK08", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPVEEWRRSAARCWAVLEPALRERLAAAPLGEALRMGCGLFGPEEAALQRLCRRARTGKEPAAARFYREEGNRQFGRCCYRDAVRLYSQAAAHEPPRSPEVALCFANRSAALFHLGHFEVCLEDIARAESHGYPDRLLPKVLLRKAECLLRLGKLQDATDTLTAVENKMTVDGIMTSPIHRMLLKKLSQLKTEIHEGSCPEPAREAHGDIQRESEIWEENGSISGASSSLSLNFSTERGRHLVASQDILPGQNLLKEKAFVSVLCPGEGDSLLLQDSSETVWDTRVTNADLYCHHCLKQLLASIPCCGCSYAKYCSQNCADVAWEQYHRTECPLGALLLTLGVFCHVALRTVLLAGFSEVSRLVEWSRDDSNKDLCNAEAGGEHPSEVLDTRAGRKVIPGCNDNGQYQSSYQAVFNLLPHVEKHSPEHKFLCMLSIVAICKKLQETGLEAAVLNGESSTTGSEQKTCGKTSDELSPELMIMAEAMLRHVLQLQCNAQAITVMQELESGDGAVVNKKPVRLATAFFPVLSLLNHSCSPNISVSFSGTAATVRASQPIPSGQEIFHCYGPHRCRMRVAERQQLLSQYFFECRCQACLDELESDVESVSMRNSFCCPSCQASMQGEEMLCCSNEACAFSVSRERLSQRLLDLQQQMEKALELLRDSKADEAIKMLLKCQIDARNFLSPEHLLMGELEDHLAQVYATLGKWQEAARHLGRSIQLVEMHHGPSSVEMGHELFKLAQILFNGFAVSEALSTIQRAEEILSVHCGPQSTQIQELQEMKTCLLELPRSILQRT", "length": 797, "header": "tr|A0A8V1AM05-1|A0A8V1AM05_CHICK Isoform 1 of Protein-lysine N-methyltransferase SMYD4 OS=Gallus gallus OX=9031 GN=SMYD4 PE=4 SV=1 CANONICAL=A0A8V1AM05-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05/entry#A0A8V1ACR3-1", "sequence": { "sequence": "MALPVEEWRRSAARCWAVLEPALRERLAAAPLGEALRMGCGLFGPEEAALQRLCRRARTGKEPAAARFYREEGNRQFGRCCYRDAVRLYSQAAAHEPPRSPEVALCFANRSAALFHLGHFEVCLEDIARAESHGYPDRLLPKVLLRKAECLLRLGKLQDATDTLTAVENKMTVDGIMTSPIHRMLLKKLSQLKTEIHEGSCPEPAREAHGDIQRESEIWEENGSISGASSSLSLNFSTERGRHLVASQDILPGQNLLKEKAFVSVLCPGEGDSLLLQDSSETVWDTRVTNADLYCHHCLKQLLASIPCCGCSYAKYCSQNCADVAWEQYHRTECPLGALLLTLGVFCHVALRTVLLAGFSEVSRLVEWSRDDSNKDLCNAEAGGEHPSEVLDTRAGRKVIPGCNDNGQYQSSYQAVFNLLPHVEKHSPEHKFLCMLSIVAICKKLQETGLEAAVLNGESSTTGSEQKTCGKTSDELSPELMIMAEAMLRHVLQLQCNAQAITVMQELESGDGAVVNKKPVRLATAFFPVLSLLNHSCSPNISVSFSGTAATVRASQPIPSGQEIFHCYDEAIKMLLKCQIDARNFLSPEHLLMGELEDHLAQVYATLGKWQEAARHLGRSIQLVEMHHGPSSVEMGHELFKLAQILFNGFAVSEALSTIQRAEEILSVHCGPQSTQIQELQEMKTCLLELPRSILQRT", "length": 698, "header": "tr|A0A8V1ACR3-1|A0A8V1ACR3_CHICK Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Gallus gallus OX=9031 GN=SMYD4 PE=4 SV=1 CANONICAL=A0A8V1AM05-1" }, "locus": { "chromosome": "19", "start_pos": 5906250, "end_pos": 5899830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071089.1", "url": "https://www.ensembl.org/id/ENSGALT00010071089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043780.1", "url": "https://www.ensembl.org/id/ENSGALP00010043780.1" } ] } }, { "isoform_ac": "A0A8V1AI18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05/entry#A0A8V1AI18-1", "sequence": { "sequence": "MALPVEEWRRSAARCWAVLEPALRERLAAAPLGEALRMGCGLFGPEEAALQRLCRRARTGKEPAAARFYREEGNRQFGRCCYRDAVRLYSQVCLEDIARAESHGYPDRLLPKVLLRKAECLLRLGKLQDATDTLTAVENKMTVDGIMTSPIHRMLLKKLSQLKTEIHEGSCPEPAREAHGDIQRESEIWEENGSISGASSSLSLNFSTERGRHLVASQDILPGQNLLKEKAFVSVLCPGEGDSLLLQDSSETVWDTRVTNADLYCHHCLKQLLASIPCCGCSYAKYCSQNCADVAWEQYHRTECPLGALLLTLGVFCHVALRTVLLAGFSEVSRLVEWSRDDSNKDLCNAEAGGEHPSEVLDTRAGRKVIPGCNDNGQYQSSYQAVFNLLPHVEKHSPEHKFLCMLSIVAICKKLQETGLEAAVLNGESSTTGSEQKTCGKTSDELSPELMIMAEAMLRHVLQLQCNAQAITVMQELESGDGAVVNKKPVRLATAFFPVLSLLNHSCSPNISVSFSGTAATVRASQPIPSGQEIFHCYGPHRCRMRVAERQQLLSQYFFECRCQACLDELESDVESVSMRNSFCCPSCQASMQGEEMLCCSNEACAFSVSRERLSQRLLDLQQQMEKALELLRDSKADEAIKMLLKCQIDARNFLSPEHLLMGELEDHLAQVYATLGKWQEAARHLGRSIQLVEMHHGPSSVEMGHELFKLAQILFNGFAVSEALSTIQRAEEILSVHCGPQSTQIQELQEMKTCLLELPRSILQRT", "length": 767, "header": "tr|A0A8V1AI18-1|A0A8V1AM05_CHICK Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Gallus gallus OX=9031 GN=SMYD4 PE=4 SV=1 CANONICAL=A0A8V1AM05-1" }, "locus": { "chromosome": "19", "start_pos": 5906250, "end_pos": 5899830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071086.1", "url": "https://www.ensembl.org/id/ENSGALT00010071086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043777.1", "url": "https://www.ensembl.org/id/ENSGALP00010043777.1" } ] } }, { "isoform_ac": "A0A8V1AK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05/entry#A0A8V1AK08-1", "sequence": { "sequence": "MALPVEEWRRSAARCWAVLEPALRERLAAAPLGEALRMGCGLFGPEEAALQRLCRRARTGKEPAAARFYREEGNRQFGRCCYRDAVRLYSQAAAHEPPRSPEVALCFANRSAALFHLGHFEVCLEDIARAESHGYPDRLLPKVLLRKAECLLRLGKLQDATDTLTAVENKMTVDGIMTSPIHRMLLKKLSQLKTEIHEGSCPEPAREAHGDIQRESEIWEENGSISGASSSLSLNFSTERGRHLVASQDILPGQNLLKEKAFVSVLCPGEGDSLLLQDSSETVWDTRVTNADLYCHHCLKQLLASIPCCGCSYAKYCSQNCADVAWEQYHRTECPLGALLLTLGVFCHVALRTVLLAGFSEVSRLVEWSRDDSNKDLCNAEAGGEHPSEVLDTRAGRKVIPGCNDNGQYQSSYQAVFNLLPHVEKHSPEHKFLCMLSIVAICKKLQETGLEAAVLNGESSTTGSEQKTCGKTSDELSPELMIMAEAMLRHVLQLQCNAQAITVMQELESGDGAVVNKKPVRLATAFFPVLSLLNHSCSPNISVSFSGTAATVRASQPIPSGQEIFHCYEMLCCSNEACAFSVSRERLSQRLLDLQQQMEKALELLRDSKADEAIKMLLKCQIDARNFLSPEHLLMGELEDHLAQVYATLGKWQEAARHLGRSIQLVEMHHGPSSVEMGHELFKLAQILFNGFAVSEALSTIQRAEEILSVHCGPQSTQIQELQEMKTCLLELPRSILQRT", "length": 740, "header": "tr|A0A8V1AK08-1|A0A8V1AM05_CHICK Computationally mapped isoform of Protein-lysine N-methyltransferase SMYD4 OS=Gallus gallus OX=9031 GN=SMYD4 PE=4 SV=1 CANONICAL=A0A8V1AM05-1" }, "locus": { "chromosome": "19", "start_pos": 5906250, "end_pos": 5899830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071088.1", "url": "https://www.ensembl.org/id/ENSGALT00010071088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043779.1", "url": "https://www.ensembl.org/id/ENSGALP00010043779.1" } ] } }, { "isoform_ac": "A0A8V1AM05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05/entry#A0A8V1AM05-1", "sequence": { "sequence": "MALPVEEWRRSAARCWAVLEPALRERLAAAPLGEALRMGCGLFGPEEAALQRLCRRARTGKEPAAARFYREEGNRQFGRCCYRDAVRLYSQAAAHEPPRSPEVALCFANRSAALFHLGHFEVCLEDIARAESHGYPDRLLPKVLLRKAECLLRLGKLQDATDTLTAVENKMTVDGIMTSPIHRMLLKKLSQLKTEIHEGSCPEPAREAHGDIQRESEIWEENGSISGASSSLSLNFSTERGRHLVASQDILPGQNLLKEKAFVSVLCPGEGDSLLLQDSSETVWDTRVTNADLYCHHCLKQLLASIPCCGCSYAKYCSQNCADVAWEQYHRTECPLGALLLTLGVFCHVALRTVLLAGFSEVSRLVEWSRDDSNKDLCNAEAGGEHPSEVLDTRAGRKVIPGCNDNGQYQSSYQAVFNLLPHVEKHSPEHKFLCMLSIVAICKKLQETGLEAAVLNGESSTTGSEQKTCGKTSDELSPELMIMAEAMLRHVLQLQCNAQAITVMQELESGDGAVVNKKPVRLATAFFPVLSLLNHSCSPNISVSFSGTAATVRASQPIPSGQEIFHCYGPHRCRMRVAERQQLLSQYFFECRCQACLDELESDVESVSMRNSFCCPSCQASMQGEEMLCCSNEACAFSVSRERLSQRLLDLQQQMEKALELLRDSKADEAIKMLLKCQIDARNFLSPEHLLMGELEDHLAQVYATLGKWQEAARHLGRSIQLVEMHHGPSSVEMGHELFKLAQILFNGFAVSEALSTIQRAEEILSVHCGPQSTQIQELQEMKTCLLELPRSILQRT", "length": 797, "header": "tr|A0A8V1AM05-1|A0A8V1AM05_CHICK Isoform 1 of Protein-lysine N-methyltransferase SMYD4 OS=Gallus gallus OX=9031 GN=SMYD4 PE=4 SV=1 CANONICAL=A0A8V1AM05-1" }, "locus": { "chromosome": "19", "start_pos": 5906250, "end_pos": 5899830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071087.1", "url": "https://www.ensembl.org/id/ENSGALT00010071087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043778.1", "url": "https://www.ensembl.org/id/ENSGALP00010043778.1" } ] } }, { "isoform_ac": "A0A8V1ANJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05/entry#A0A8V1ANJ6-1", "sequence": { "sequence": "MALPVEEWRRSAARCWAVLEPALRERLAAAPLGEALRMGCGLFGPEEAALQRLCRRARTGKEPAAARFYREEGNRQFGRCCYRDAVRLYSQAAAHEPPRSPEVALCFANRSAALFHLGHFEVCLEDIARAESHGYPDRLLPKVLLRKAECLLRLGKLQDATDTLTAVENKMTVDGIMTSPIHRMLLKKLSQLKTEIHEGSCPEPAREAHGDIQRESEIWEENGSISGASSSLSLNFSTERGRHLVASQDILPGQNLLKEKAFVSVLCPGEGDSLLLQDSSETVWDTRVTNADLYCHHCLKQLLASIPCCGCSYAKYCSQNCADVAWEQYHRTECPLGALLLTLGVFCHVALRTVLLAGFSEVSRLVEWSRDDSNKDLCNAEAGGEHPSEVLDTRAGRKVIPGCNDNGQYQSSYQAVFNLLPHVEKHSPEHKFLCMLSIVAICKKLQETGLEAAVLNGESSTTGSEQKTCGKTSDELSPELMIMAEAMLRHVLQLQCNAQAITVMQELGPHRCRMRVAERQQLLSQYFFECRCQACLDELESDVESVSMRNSFCCPSCQASMQGEEMLCCSNEACAFSVSRERLSQRLLDLQQQMEKALELLRDSKADEAIKMLLKCQIDARNFLSPEHLLMGELEDHLAQVYATLGKWQEAARHLGRSIQLVEMHHGPSSVEMGHELFKLAQILFNGFAVSEALSTIQRAEEILSVHCGPQSTQIQELQEMKTCLLELPRSILQRT", "length": 736, "header": "tr|A0A8V1ANJ6-1|A0A8V1ANJ6_CHICK Computationally mapped isoform of SET and MYND domain containing 4 OS=Gallus gallus OX=9031 GN=SMYD4 PE=4 SV=1 CANONICAL=A0A8V1AM05-1" }, "locus": { "chromosome": "19", "start_pos": 5906250, "end_pos": 5899830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071085.1", "url": "https://www.ensembl.org/id/ENSGALT00010071085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043776.1", "url": "https://www.ensembl.org/id/ENSGALP00010043776.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417562", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5K1VBK2-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "SMYD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAEALSDIFLHSSLLLQPEDEMFLKRLSGGYLVGKDPGAPLFYREEGNKKFHEKDYMGATLLYSKGVAHSRPSTEDISLCYANRSAALFHLGQYETCLKDIVRAQSHGYPENLQPKMLLRKAECLVTLGRLQEASQTISDLESNFAATPTLAASQFQILQRTLCRLKRKVQEKETLTETFPALLTKALEDMELREENVHVRGASSSVSLRVDPLKGRSLVATKDILPGELLVKEDAFVSVLNPGEMPPRHEGLESKWDTRVTNGDLYCHRCLKPTLATVPCDGCSYAKYCSQECLQQAWDLYHSVECSLGGLLLTLGVFCHVALRSTLLARFEDVGKVRMTLCGETCNRDVSSPEGKNLAQALSYDLGGEREQRGKTVETSVPGCGIDGKYENNYNAVFHLLPHTENHSPEHKFLCALSVSALGRQLQAAGSQPFTAGLKSSKLEAAEAPVLYPEWNIWGVAMLRHMLQLQCNAQAITAIQQTGSKGSLITEHRQVRLATGLFPVVSLLNHSCSPNASVSFISTVATVRASQPIRKGQEVLHCYGPHESRMGVAERHQKLRSQYFFDCNCPPCEREKQRPSALEPRREAFCCHRCRALLQGDDVLSCGSTSCPASVRRHHLDSRLQDLQQQVGLARKLLRNCKAERAIQLLLGCQHDAESFLSAEHSVVGEIADDLAQAYAALGDWKKSASHLQKSLRVVEVRHGPSSVEMGHELFKLAQIFFNGLAIPEALNTIQRAEKVLLVHYGPWNDEIQELQKMKSCLMDLLPIPMGPSE", "length": 803 }, "evidence": [ { "id": "A0A8V1AM05", "url": "https://omabrowser.org/oma/group/A0A8V1AM05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4AEC7-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "Smyd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLPVDEWKSYLLEKWALLPKSVQVTISTAETLSDIFLHSSSLLQPEDEMFLKQLSSSCSVEKDSGAPLFYREEGNKRFQEKEYMGAAVLYSKGVSHSRPNTEDISLCYANRSAALFHLGQHEACLKDIVRAGMHGYPERLQPKLMIRKTECLVNLGRLQEARQTISDLENSLTTKPTLMPSSHQILQRNVQQLKMKIQEKETLPESFPAALTKALEDMALGEENKQISGASLSVSLCTDPLKGRHLVATKDILPGELLVKEDAFVSVLNPGEMPPLRHCLENKWDTRVTSADLYCHRCLRHTLATVPCGGCSYAKYCSQECVQQAWDHYHSTECSLGGLLLTLGVFCHVALRMTLLARFEDVDRVIRMICDKTGRKDTCLPESKDLVKTFGYTNQGESEENSETCEPSIPGCNVNGKYENNYDAVLSLLPHTEKHSPEHKFICAVSVSALCRQLKATSLQAQTTGLKSPRLKAVTPGLCTDLTVWGVAMLQHMLQLQCNAQAITSICYAGSKESIITNSRQVRLATGVFPVVSLLNHSCSPNTSVSFTSTVATIRAAQQIAKGQEILHCYGPHESRMGVAERQQRLSSQYFFDCSCPACHAETLRAAVAPRWEAFCCNTCRVPMQGNDVLSCSNESCTNSVSRDRLVSRLQDLQQQVHTAQKLLRSDRPEQAIQQLLECQRAAENFLSAEHTVLGEIEDGLAQAYATLGDWRQSAAHVQKSLQVVEARHGPSSVEIGHELFKLAQVLFNGLAVPEALDAIWKAEKILLVHCGPESDEVQELREMRSCLLDSSFTPVRPLV", "length": 801 }, "evidence": [ { "id": "A0A8V1AM05", "url": "https://omabrowser.org/oma/group/A0A8V1AM05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BEP0-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "SMYD4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLPVDEWKSYILQKWSLLPKSIQVTISTAETLHDLFLHSSPLLQPEDEMFLKRLSGGYLVGKDPDASLFYREKGNQKFQAKDYMGAAVLYSKGVSHSGPSSTDISLCYANRSAALFHLGQYEICLKDIVRAQTHGYPERLQPKLLLRKAECLVTLGRPQEASQTVTDLESSFAAKPTLSASQFQILQRTLCRVKVKVQEKENLPEIFPEALTKTFEGVDLREENEQIPGASSSVSLHIDPLKGRYLVATKDILPGELLVKEDAFVSVLNPGEVPLRPRGLESKWDIQVTNGDLHCHRCLRHTLAPVPCDGCSYAKYCSQECMQQAWDRYHSVECSLGALLLTLGVFCHVALRSTLLARFEDVGKVTKKLCGEMSNQGICLPESKNPVQTLKYDLGGEGDKKDKAVETPIPGCDINGKYERNYNAIFHLLPHTENHSPEHKFLCALSVSALCRQLEAAGLQAFTTDLKPTKLKAAEPPVLCAELSVWGVAMLRHMLQLQCNAQAITTIQQTGSKESLITDTRRVRLATALFPVVSLLNHSCSPNTSVSFIGTIATIRASQLIRSGQEILHCYGPHESRMGVAERRQKLRSQYFFDCDCPPCEREKQRPSAGPGRGAFRCHRCRALLQGDDVLSCSGPACMESVSRDLLVSRLQDLQRQVGAAQKHLRNGRLEVAIQLLLGCQSDAESFLSAEHSVVGEIEDALAQAYAALGDWEKSATHLQKSLQVVEVHHGPSSVEMGHELFKLAQVFFNGCAVPEALKTIQKAEKVLLVHYGPWNDEIRELQKMKSCLLDLLPIPVGPKE", "length": 802 }, "evidence": [ { "id": "A0A8V1AM05", "url": "https://omabrowser.org/oma/group/A0A8V1AM05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4HR71-1", "protein_name": "Tetratricopeptide repeat (TPR)-like superfamily protein", "gene_name": "TPR9", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEKLKSLIPEDLLQTVKSSSVDDLLSTSSSLLRLFLGLPQFHQAVSELANPELGCCGKNEETSLDLKRRGNHCFRSRDFDEALRLYSKALRVAPLDAIDGDKSLLASLFLNRANVLHNLGLLKESLRDCHRALRIDPYYAKAWYRRGKLNTLLGNYKDAFRDITVSMSLESSLVGKKQLQNELKAIPDYQNNQTLEHDEYRPSNDAGVDHLPSVQMEVKLRCVSTKEKGRGMVSECDIEEASVIHVEEPFSVVISKSCRETHCHFCLNELPADTVPCPSCSIPVYCSESCQIQSGGMLSTNEMDKHHIFQKLPDDIVEHIKGVTSADIYYFATDLIQEHQHECRGANWPAVLPSDAVLAGRIIMKLINQGKAATDLSNLQEILELSHTYSKMNPENKLELHLLSIVLIWCLSKSSCPNLSVCEASVTQTIILLSQIKVNSIAVARMKSSGDSFKCLPSGNISTKEPIQSLEQIRVGQALYKTGSLFNHSCKPNIHLYFLSRGLIMQTTEFVPTGCPLELSYGPEVGKWDCKNRIRFLEEEYFFHCRCRGCAQINISDLVINGYGCVNTNCTGVVLDSNVATCESEKLNHFFTAPRNVDQQVQMREKVYADVGEVASSLLSKPSGSLHIEPEICLKCGSRCDIENSHAEVNKAWNHMRRVEELMNSGRANYSVLSDCSRSIAVLRTFLHMYNKDIADAEDKVAQACYLAGELVDARKHCEASIKILKRLYEDEHVVIGNEMVKLASIQLASGDSSGAWDTTKRSSQIFSKYYGSHAETLFSYLPCLKQETAKAVNLSTS", "length": 798 }, "evidence": [ { "id": "A0A8V1AM05", "url": "https://omabrowser.org/oma/group/A0A8V1AM05/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q08C84-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "smyd4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLPCQDWVCHVEQKWAELRSEETERFSLLTDIDAIFNYGLSLICPEDLNILSRISEKFSVKKSPETASEFRQQGNLSFKVKDYPAAVLHYSKGVCHADKNTDELSLCYANRSAALFYQGLYQACLEDIRRSLEAGYPSHLQDKLQTRQTACQNQLRKAEKPNIPHTDHQLSPCQKTVNSTGHLSDGVSVYFSSDKGRHMLVMENKPAGEVVLEDEAYCSVLIPANIFNTGTNKAVETFGTEDRHCHHCLSQSLSFVPCPKCSYARYCGESCQKDAWDQWHQWECPVGADLLAIGVLGHLALRVVLKAGQTEVQMGIKNTKDHVTTYKNDSPVQLSLGGDCGKSLDHTDCFHGSSYMGIYSLLPHVAQHSPASRFLMAITMAVIYGKLQGGPPPNKWMSFKDEGVKASWQPEMSMLGATALRHMMQLRCNAQAITAVRVKEESGMAVQSSSEIRIATAIFPVLSLLNHSCSPNTSISFTTGFQPDPHNQLGCSEGHFDHPKGSRSGVTVTVRASKDLTAGQEILHCYGPHRSRMEVKERQRLLLEQYFFQCVCQACQRDLSEGSPNAKEHTAPGMKCVKCGKPLQSHTDGYTCSWSSCGHQISSADVQNRLQGFQLLLDEAVHLMEQDRLNEALHILQSAFSQANSILTETHPFQGELADALARLYASTGEWSLAASHLKRSLVAIQAQFGEDSIELGRQLFKLAQLHFNGRDGVASLSVIPRARRLLSLHCSPRCEELQELSEMEHCLQGLL", "length": 753 }, "evidence": [ { "id": "A0A8V1AM05", "url": "https://omabrowser.org/oma/group/A0A8V1AM05/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BTK5-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "Smyd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLPVDEWKSYLLKKWASLPKSVQDTISTAETLSDIFLPSSSLLQPEDEMFLKELSSSYSVEKDNDAPLFYREEGNRKFQEKEYTDAAVLYSKGVSHSRPNTEDISLCYANRSAALFHLGQYEACLKDIVEAGMHGYPERLQPKMMVRKTECLVNLGRLQEARQTISDLESSLTAKPTLVLSSYQILQRNVQHLKIKIQEKETLPEPIPAALTNAFEDIALGEENTQISGASLSVSLCTHPLKGRHLVATKDILPGELLVKEDAFVSVLIPGEMPRPHHCLENKWDTRVTSGDLYCHRCLKHTLATVPCGSCSYAKYCSQECMQQAWDLYHSTECSLGGLLLTLGVFCHVALRMTLLARFEDVDRVVRMLCDEVGSTDTCLPESKNLVKAFDYTSQGESEEKSKIGEPPIPGCNVNGKYGSNYNAIFSLLPHTEKHSPEHRFICAISVSALCRQLKADSVQAQTLKSPKLKAVTPGLCADLTVWGAAMLRHMLQLQCNAQAITSICHTGSNESIITNSRQIRLATGIFPVVSLLNHSCRPNTSVSFTGTVATVRAAQRIAKGQEILHCYGPHESRMGVAERQQRLSSQYFFDCRCGACHAETLRAAAAPRWEAFCCKTCRALMQGNDVLSCSNESCTNSVSRDQLVSRLQDLQQQVCMAQKLLRTGKPEQAIQQLLRCREAAESFLSAEHTVLGEIEDGLAQAHATLGNWLKSAAHVQKSLQVVETRHGPSSVEIGHELFKLAQVLFNGLAVPEALSAIWKAERILLVHCGPESEEVRELREMRSCLLDSSFVPVGPLV", "length": 799 }, "evidence": [ { "id": "A0A8V1AM05", "url": "https://omabrowser.org/oma/group/A0A8V1AM05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYR2-1", "protein_name": "Protein-lysine N-methyltransferase SMYD4", "gene_name": "SMYD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLPVDEWKSYLLQKWASLPTSVQVTISTAETLRDIFLHSSSLLQPEDELFLKRLSKGYLVGKDSDAPLFYREEGNKKFQEKDYTGAAVLYSKGVSHSRPNTEDMSLCHANRSAALFHLGQYETCLKDINRAQTHGYPERLQPKIMLRKAECLVALGRLQEASQTISDLERNFTATPALADVLPQTLQRNLHRLKMKMQEKDSLTESFPAALAKTLEDAALREENEQLSNASSSIGLCVDPLKGRCLVATKDILPGELLVQEDAFVSVLNPGELPPPHHGLDSKWDTRVTNGDLYCHRCLKHTLATVPCDGCSYAKYCSQECLQQAWELYHRTECPLGGLLLTLGVFCHIALRLTLLVGFEDVRKIITKLCDKISNKDICLPESNNQVKTLNYGLGESEKNGNIVETPIPGCDINGKYENNYNAVFNLLPHTENHSPEHKFLCALCVSALCRQLEAASLQAIPTERIVNSSQLKAAVTPELCPDVTIWGVAMLRHMLQLQCNAQAMTTIQHTGPKGSIVTDSRQVRLATGIFPVISLLNHSCSPNTSVSFISTVATIRASQRIRKGQEILHCYGPHKSRMGVAERQQKLRSQYFFDCACPACQTEAHRMAAGPRWEAFCCNSCGAPMQGDDVLRCGSRSCAESAVSRDHLVSRLQDLQQQVRVAQKLLRDGELERAVQRLSGCQRDAESFLWAEHAVVGEIADGLARACAALGDWQKSATHLQRSLYVVEVRHGPSSVEMGHELFKLAQIFFNGFAVPEALSTIQKAEEVLSLHCGPWDDEIQELQKMKSCLLDLPPTPVGPAL", "length": 804 }, "evidence": [ { "id": "A0A8V1AM05", "url": "https://omabrowser.org/oma/group/A0A8V1AM05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" }, { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "51736", "name": "", "equation": "L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A0A0MQ47-1", "A0A8V0Y4K0-1", "E1C5V0-1", "A0A8V0ZUS5-1", "Q5F3V0-1" ], "evidence": [ { "id": "51736", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51736" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0A0MQ47", "gene_name": "SMYD2", "activity": [ { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A0A0MQ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MQ47" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0A0A0MQ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0A0MQ47" } ] } ] }, { "uniprot_ac": "A0A8V0Y4K0", "gene_name": "SETD7", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0Y4K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4K0" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0A8V0Y4K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4K0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUS5", "gene_name": "KMT5A", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8V0ZUS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUS5" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A8V0ZUS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUS5" } ] } ] }, { "uniprot_ac": "E1C5V0", "gene_name": "SMYD2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "E1C5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5V0" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "E1C5V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5V0" } ] } ] }, { "uniprot_ac": "Q5F3V0", "gene_name": "SMYD4", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q5F3V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3V0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AM05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 334, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AM05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM05" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 569, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 540, "end_pos": 542 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM75-1", "uniprot_ac": "A0A8V1AM75", "uniprot_id": "A0A8V1AM75_CHICK", "mass": { "chemical_mass": 101079.0, "monoisotopic_mass": 101079.0 }, "refseq": { "ac": "XP_415508", "name": "SH2 domain-containing protein 3C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415508" }, "gene_names": [ { "name": "SH2D3C", "type": "recommended", "evidence": [ { "id": "A0A8V1AM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" } ] }, { "name": "SH2D3C", "type": "synonym", "evidence": [ { "id": "XP_415508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415508" } ] } ], "protein_names": [ { "name": "SH2 domain containing 3C", "type": "synonym", "evidence": [ { "id": "A0A8V1AM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75/entry#names_and_taxonomy" } ] }, { "name": "SH2 domain-containing protein 3C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415508", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415508" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415508.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415508" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH2D3C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75", "locus": { "chromosome": "17", "start_pos": 5599545, "end_pos": 5579761, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029143", "url": "https://www.ensembl.org/id/ENSGALG00010029143" } ] } } ], "crossref": [ { "id": "A0A8V1AM75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM75", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417225", "url": "https://www.ncbi.nlm.nih.gov/gene/417225", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MVHNSRM", "url": "https://omabrowser.org/oma/group/MVHNSRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAV9", "url": "https://www.orthodb.org/?gene=A0A8V1AAV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIA2", "url": "https://www.orthodb.org/?gene=A0A8V1AIA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKG0", "url": "https://www.orthodb.org/?gene=A0A8V1AKG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM75", "url": "https://www.orthodb.org/?gene=A0A8V1AM75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415508", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGQKRGGFKKFKFFKFKGFESLSSIPRSFTLRRVSVVPSSPESLGMCLPPPQGFLEEAFDSTQDDLNTMPKGPGPYARSSDMYSHMGTMPRLSFGKVGKSLGKARGTQSCREKGSSRDKIPSTAPLPVPKALKMPGTLNLGKDPSSASGKAEQEKEEALPSGSPGAEKARMDQEIPGNSPSPGMEAPSPSLAPSPSAASGAETTDGDFQEKGQERPSESSPDSHHDGLESSSEYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSESLVQRNGDFLIRDSLTSVGDYVLTCRWRNEPLHFKINKVTVKSSDGRTRVQYLFEQESFDNVPALVRFYVGNRKAISEQSGAIVYCPINRTFPLRYLEASYGLANGKHGGSHSPASQKGGHIKRRSITMTDGLTADKITRAEGCSTSVSLPHHRDIIRNCAVSVDQIQDLHSPMSPISENPTSPAYSTVTRLKPHACQAAPASPVIRRSSEPQLCPGSSNKPLPDPAHSTHSTPCHGYARASPSPSVNSYSDPDTGHYCQLHPTSPSSRERPAHDTKQLPAKSYVERLKVEEGQRGTVENGSGEAEGGQRLKGERDFVGFVPPTVETCSSFNPAAFQSLLIPLENKPLEMAVLKKVKELLADADAKTLAKHITKVDCVVARILGVSAEMQRLMGVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKSTMGNMFSFAAVMNALEMAQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLTNTTFPHVMPLVTLLERDDALVDSPEPWEATDNGVEVVMAHLEAARMVAHHGGLYHTNAEVKLQGFQGRAELLEIFSTEFQLRLLWGSRGAESSQAERYEKFDKVLTALSHKLEPAVRFSEL", "length": 922, "header": "tr|A0A8V1AM75-1|A0A8V1AM75_CHICK Isoform 1 of SH2 domain containing 3C OS=Gallus gallus OX=9031 GN=SH2D3C PE=4 SV=1 CANONICAL=A0A8V1AM75-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75/entry#A0A8V1AAV9-1", "sequence": { "sequence": "MRHALTSGGFCAAPGSGQGKGIRAGGGNRPHIPAGREGRAGGGLGREGGGSATARAPHVPAQSQARERPQSFSPHPGAEALAEPMTAVGRRFPTLGQGSHHDGLESSSEYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSESLVQRNGDFLIRDSLTSVGDYVLTCRWRNEPLHFKINKVTVKSSDGRTRVQYLFEQESFDNVPALVRFYVGNRKAISEQSGAIVYCPINRTFPLRYLEASYGLANGKHGGSHSPASQKGGHIKRRSITMTDGLTADKITRAEGCSTSVSLPHHRDIIRNCAVSVDQIQDLHSPMSPISENPTSPAYSTVTRLKPHACQAAPASPVIRRSSEPQLCPGSSNKPLPDPAHSTHSTPCHGYARASPSPSVNSYSDPDTGHYCQLHPTSPSSRERPAHDTKQLPAKSYVERLKVEEGQRGTVENGSGEAEGGQRLKGERDFVGFVPPTVETCSSFNPAAFQSLLIPLENKPLEMAVLKKVKELLADADAKTLAKHITKVDCVVARILGVSAEMQRLMGVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKSTMGNMFSFAAVMNALEMAQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLTNTTFPHVMPLVTLLERDDALVDSPEPWEATDNGVEVVMAHLEAARMVAHHGGLYHTNAEVKLQGFQGRAELLEIFSTEFQLRLLWGSRGAESSQAERYEKFDKVLTALSHKLEPAVRFSEL", "length": 796, "header": "tr|A0A8V1AAV9-1|A0A8V1AAV9_CHICK Computationally mapped isoform of SH2 domain containing 3C OS=Gallus gallus OX=9031 GN=SH2D3C PE=4 SV=1 CANONICAL=A0A8V1AM75-1" }, "locus": { "chromosome": "17", "start_pos": 5599134, "end_pos": 5583055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070423.1", "url": "https://www.ensembl.org/id/ENSGALT00010070423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043114.1", "url": "https://www.ensembl.org/id/ENSGALP00010043114.1" } ] } }, { "isoform_ac": "A0A8V1AIA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75/entry#A0A8V1AIA2-1", "sequence": { "sequence": "MTERCSLWSALSAAACCFYRGSFMQVQFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSESLVQRNGDFLIRDSLTSVGDYVLTCRWRNEPLHFKINKVTVKSSDGRTRVQYLFEQESFDNVPALVRFYVGNRKAISEQSGAIVYCPINRTFPLRYLEASYGLANGKHGGSHSPASQKGGHIKRRSITMTDGLTADKITRAEGCSTSVSLPHHRDIIRNCAVSVDQIQDLHSPMSPISENPTSPAYSTVTRLKPHACQAAPASPVIRRSSEPQLCPGSSNKPLPDPAHSTHSTPCHGYARASPSPSVNSYSDPDTGHYCQLHPTSPSSRERPAHDTKQLPAKSYVERLKVEEGQRGTVENGSGEAEGGQRLKGERDFVGFVPPTVETCSSFNPAAFQSLLIPLENKPLEMAVLKKVKELLADADAKTLAKHITKVDCVVARILGVSAEMQRLMGVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKSTMGNMFSFAAVMNALEMAQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLTNTTFPHVMPLVTLLERDDALVDSPEPWEATDNGVEVVMAHLEAARMVAHHGGLYHTNAEVKLQGFQGRAELLEIFSTEFQLRLLWGSRGAESSQAERYEKFDKVLTALSHKLEPAVRFSEL", "length": 711, "header": "tr|A0A8V1AIA2-1|A0A8V1AM75_CHICK Computationally mapped isoform of SH2 domain containing 3C OS=Gallus gallus OX=9031 GN=SH2D3C PE=4 SV=1 CANONICAL=A0A8V1AM75-1" }, "locus": { "chromosome": "17", "start_pos": 5599134, "end_pos": 5588087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070422.1", "url": "https://www.ensembl.org/id/ENSGALT00010070422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043113.1", "url": "https://www.ensembl.org/id/ENSGALP00010043113.1" } ] } }, { "isoform_ac": "A0A8V1AKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75/entry#A0A8V1AKG0-1", "sequence": { "sequence": "MDGSMHQRAQGPPAQQDTEVAPTQLLCWWHTHPPLTHVLPSGNAPTVVAESVAKGEVTPSLSLQGREEGKLHPPGSGAPVLFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSESLVQRNGDFLIRDSLTSVGDYVLTCRWRNEPLHFKINKVTVKSSDGRTRVQYLFEQESFDNVPALVRFYVGNRKAISEQSGAIVYCPINRTFPLRYLEASYGLANGKHGGSHSPASQKGGHIKRRSITMTDGLTADKITRAEGCSTSVSLPHHRDIIRNCAVSVDQIQDLHSPMSPISENPTSPAYSTVTRLKPHACQAAPASPVIRRSSEPQLCPGSSNKPLPDPAHSTHSTPCHGYARASPSPSVNSYSDPDTGHYCQLHPTSPSSRERPAHDTKQLPAKSYVERLKVEEGQRGTVENGSGEAEGGQRLKGERDFVGFVPPTVETCSSFNPAAFQSLLIPLENKPLEMAVLKKVKELLADADAKTLAKHITKVDCVVARILGVSAEMQRLMGVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKSTMGNMFSFAAVMNALEMAQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLTNTTFPHVMPLVTLLERDDALVDSPEPWEATDNGVEVVMAHLEAARMVAHHGGLYHTNAEVKLQGFQGRAELLEIFSTEFQLRLLWGSRGAESSQAERYEKFDKVLTALSHKLEPAVRFSEL", "length": 765, "header": "tr|A0A8V1AKG0-1|A0A8V1AM75_CHICK Computationally mapped isoform of SH2 domain containing 3C OS=Gallus gallus OX=9031 GN=SH2D3C PE=4 SV=1 CANONICAL=A0A8V1AM75-1" }, "locus": { "chromosome": "17", "start_pos": 5599134, "end_pos": 5592572, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070421.1", "url": "https://www.ensembl.org/id/ENSGALT00010070421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043112.1", "url": "https://www.ensembl.org/id/ENSGALP00010043112.1" } ] } }, { "isoform_ac": "A0A8V1AM75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75/entry#A0A8V1AM75-1", "sequence": { "sequence": "MAEGQKRGGFKKFKFFKFKGFESLSSIPRSFTLRRVSVVPSSPESLGMCLPPPQGFLEEAFDSTQDDLNTMPKGPGPYARSSDMYSHMGTMPRLSFGKVGKSLGKARGTQSCREKGSSRDKIPSTAPLPVPKALKMPGTLNLGKDPSSASGKAEQEKEEALPSGSPGAEKARMDQEIPGNSPSPGMEAPSPSLAPSPSAASGAETTDGDFQEKGQERPSESSPDSHHDGLESSSEYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSESLVQRNGDFLIRDSLTSVGDYVLTCRWRNEPLHFKINKVTVKSSDGRTRVQYLFEQESFDNVPALVRFYVGNRKAISEQSGAIVYCPINRTFPLRYLEASYGLANGKHGGSHSPASQKGGHIKRRSITMTDGLTADKITRAEGCSTSVSLPHHRDIIRNCAVSVDQIQDLHSPMSPISENPTSPAYSTVTRLKPHACQAAPASPVIRRSSEPQLCPGSSNKPLPDPAHSTHSTPCHGYARASPSPSVNSYSDPDTGHYCQLHPTSPSSRERPAHDTKQLPAKSYVERLKVEEGQRGTVENGSGEAEGGQRLKGERDFVGFVPPTVETCSSFNPAAFQSLLIPLENKPLEMAVLKKVKELLADADAKTLAKHITKVDCVVARILGVSAEMQRLMGVSSGMELLTLPHGHQLRLDLLERFHTMSIMIAVDILGCTGSTEERAALLHKTIQLAAELKSTMGNMFSFAAVMNALEMAQIARLEQTWMVLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLTNTTFPHVMPLVTLLERDDALVDSPEPWEATDNGVEVVMAHLEAARMVAHHGGLYHTNAEVKLQGFQGRAELLEIFSTEFQLRLLWGSRGAESSQAERYEKFDKVLTALSHKLEPAVRFSEL", "length": 922, "header": "tr|A0A8V1AM75-1|A0A8V1AM75_CHICK Isoform 1 of SH2 domain containing 3C OS=Gallus gallus OX=9031 GN=SH2D3C PE=4 SV=1 CANONICAL=A0A8V1AM75-1" }, "locus": { "chromosome": "17", "start_pos": 5599134, "end_pos": 5579850, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070424.1", "url": "https://www.ensembl.org/id/ENSGALT00010070424.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043115.1", "url": "https://www.ensembl.org/id/ENSGALP00010043115.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A5D5-1", "protein_name": "SH2 domain containing 3C", "gene_name": "Sh2d3c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEMPKKTGKKFKFFKFKGLGSLSNLPRSFSLRRSSASPSIRSCPEPDTFEATQDDLVTLPKSPPAYARSSDMYSHMGTMPRPNIKKAQKQKAVQKAQEVSRESHLVSRGLPEPPDFEAAKEAEKGTETPLEDTTPSAVEVDPMRKLAGLTVDTAEKQIPGDAYPERAAAELEAAGDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWHNQTLHFKINKVVVEAGESYTHIRYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLSQGSSKAASPASPSGPKGSHMKRRSVTMTDGLTSDKVTRGDGCPNSTSLPHPRDSIRNCALSMDQIPDLHSPLSPISESPSSPAYSTVTRVHAASAAPCTAQPASPVARRSSEPQLCPGGAPKPPGESDRGPHASPSHTLCKASPSPSLSSYSDPDSGHYCQLQPPVRCSREPTAGETPRKARSSAERQKELSENGVPEGEWGKTFTAPVAEATSSFNLATFQSQLIPKENRPLEVGLLRKVKELLSEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRQDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALEMAQISRLEQTWMTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPFITLLECDSAPAEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGANSSQAWRYEKFDKVLTALSHKLEPAIRSSEL", "length": 853 }, "evidence": [ { "id": "A0A8V1AM75", "url": "https://omabrowser.org/oma/group/A0A8V1AM75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N5H7-1", "protein_name": "SH2 domain-containing protein 3C", "gene_name": "SH2D3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLEPDTFEATQDDMVTVPKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAARQAQEAGPKPNLVPGGVPDPPGLEAAKEVMVKATGPLEDTPAMEPNPSAVEVDPIRKPEVPTGDVEEERPPRDVHSERAAGEPEAGSDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL", "length": 860 }, "evidence": [ { "id": "A0A8V1AM75", "url": "https://omabrowser.org/oma/group/A0A8V1AM75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZS8-1", "protein_name": "SH2 domain-containing protein 3C", "gene_name": "Sh2d3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEMPKKTGRKFKFFKFKGLGSLSNLPRSFSLRRSSASASIRSCPEPDTFEATQDDMVTLPKSPPAYARSSDMYSHMGTMPRPNIKKAQKQQAVQKAQEVSRESHLVSRRLPEPPDLEAAKEAGEGTEALLEDTAPSAVEVDPMRELEDLTVDTEKEQVPGDVSPERTAAELEAAGDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWHNQALHFKINKVVVKAGESYTHIRYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLSQGSSKTASPASPSGSKGSHMKRRSITMTDGLTTDKVTRSDGCPNSTSLPHPRDSIRNCALSMDQIPDLHSPLSPISESPSSPAYSTVTRVHAPSATPSTSAQPASPVARRSSEPQLCPGNTPKPPGESDRAPHASPSHTLCKASPSPSLSSYSDPDSGHYCQLQPPVRGSREQAAGETPRKARGSGERQKELLENGVSDGEWGKTFTVPVVEATSSFNLATFQSQLIPKENRPLEVALLRKVKELLSEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALEMAQISRLEQTWMTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPFITLLECDSAPAEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGANSSQAWRYEKFDKVLTALSHKLEPAIRSSEL", "length": 854 }, "evidence": [ { "id": "A0A8V1AM75", "url": "https://omabrowser.org/oma/group/A0A8V1AM75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VMJ4-1", "protein_name": "Breast cancer anti-estrogen resistance protein 3 homolog", "gene_name": "Dmel\\CG9098", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNTQARQLENRQVPNRRSSILWNFRYSNTVRRREDLAVMVHNSRMSISEWLDLLELQQYEGNLQEFSTVDDVVDITDKELKQFGVRGAHRQRMVNSLLGVRAKRRQSMNLEAMSSAPRAVPRRKNSCPLVYLGENPQDMAGSGDSGPGVITTKSGKVLKQLTFDETSTIYEELRPRSKCNSPHWAIEDSRMEGYGSSNATTPLATAQPSPSEQQEAIALKKALEWELSLDARELRSHAWYHGALPRQRAEEIVQREGDFLVRDCASQPDNYVLSCRSKAAVLHFVLNKLVLQPETVYERVQYQFEEDAFDTVPDLITFYVGSGKPISSASGALIQFPCNRTYPLSFYGHKIVGNQLHTQMLAGLRGLSPLNSPMGSNGAVGAGMNATFRFEPQQQQQQQLSPMAGSPASPHCSPPRARREVPPPPRLPCKKQQRSQSLTPAQAMLVSNINKLQEQQLQMQELENGNGNGIMRFQTIARCNPTSEQHLESKFTTHSLPRPNTSAAHALRQQAVARISSLARNCSLDSPSDSRPPSPPPKPRKEPMAAVLAYQASGSDSGNGSGDSALGDACEASVQRGVIIKNPRFMTTSVSNGTLKSFTEFDVLAAEEELFTMAIEEVKTASKFDFENFVTLLLPSVENKPLDGDALNTFKMMLLETGPKLLAEHITRIDIALFLEEPSNEEDYYLSCSGLELLTLPHGKVFREDIIERTQCIKLMVAVTILTCQTDLDRAQLLSKWIQIAVETKTALGNLFGFCAIMLGLCMQQIQKLDQAWHILRQQYTDSAFTFEAKLRPTLSIMNEASNPQAPNTTVPHVLLYALLIDRPVMDIINHSNIDDRPALYHTCIAPWESKADDFGMTINFQHLDASRGFLKNLELYRKNAKIILEDASPRLDELLADAFRTEFHVKFLWGSSGATAKAEDRHNKLEKVLTLMADKFCMMAEQ", "length": 944 }, "evidence": [ { "id": "A0A8V1AM75", "url": "https://omabrowser.org/oma/group/A0A8V1AM75/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 648, "end_pos": 916, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM75" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 372, "start_aa": "Trp", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 373, "end_pos": 375 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 802, "end_pos": 804 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BYV6-1", "uniprot_ac": "E1BYV6", "uniprot_id": "E1BYV6_CHICK", "mass": { "chemical_mass": 52134.0, "monoisotopic_mass": 52134.0 }, "refseq": { "ac": "XP_004946147", "name": "nuclear prelamin A recognition factor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946147" }, "gene_names": [ { "name": "NARF", "type": "recommended", "evidence": [ { "id": "E1BYV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" } ] }, { "name": "NARF", "type": "synonym", "evidence": [ { "id": "XP_004946147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946147" } ] } ], "protein_names": [ { "name": "Nuclear prelamin A recognition factor", "type": "recommended", "evidence": [ { "id": "E1BYV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYV6/entry#names_and_taxonomy" } ] }, { "name": "Iron-only hydrogenase-like protein 2", "type": "synonym", "evidence": [ { "id": "E1BYV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYV6/entry#names_and_taxonomy" } ] }, { "name": "nuclear prelamin A recognition factor", "type": "synonym", "evidence": [ { "id": "XP_004946147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946147" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946147" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYV6", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NARF", "url": "https://www.uniprot.org/uniprotkb/E1BYV6", "locus": { "chromosome": "18", "start_pos": 4103066, "end_pos": 4118751, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029150", "url": "https://www.ensembl.org/id/ENSGALG00010029150" } ] } } ], "crossref": [ { "id": "E1BYV6", "url": "https://alphafold.ebi.ac.uk/entry/E1BYV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001603", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001603", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417341", "url": "https://www.ncbi.nlm.nih.gov/gene/417341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417341", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IKFCEHY", "url": "https://omabrowser.org/oma/group/IKFCEHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIC0", "url": "https://www.orthodb.org/?gene=A0A8V1AIC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BYV6", "url": "https://www.orthodb.org/?gene=E1BYV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYV6", "url": "https://www.uniprot.org/uniprotkb/E1BYV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BYV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKCENCTKKECSKKQKNDDAQSTSVDVLSSNDDFEEKNEFFTLANAKILLSDCLACDNCMTSEEGARVFQQNQKEFFRILNLNKKCDTSKHKVLAVSICPQSLPYFAAKFSLSVNDAAKRLCGFLKSLGVHYVFDTTIAADFSILESQREFVQRYQRRNQEEHALPMFASACPGWIRYAERVLTNLVTPHICTAKSPQQIMGSLVKGYFARQQNLSPEKIFHVVVAPCYDKKLEALREDFYTALYNSQEVDCVLTSGEIVQIMEQKNVSMKDVTEVAVDSLFGEIKEGDVVRHDGKRSDGYLEHIFKHAAKELFGMDVKEITYKALKNKDFQEVTLEKDGETVLRFAAAYGFRNIQNMVLKLKKGKFLYHFVEVLACPGGCLNGKGQTQTEDGKPDKALLSQMEDVYAAIPVRLPEANVYVQKMYQDWLEGMDSRKVQETLHTKYSAVNQTASNLDIKW", "length": 459, "header": "tr|E1BYV6-1|E1BYV6_CHICK Isoform 1 of Nuclear prelamin A recognition factor OS=Gallus gallus OX=9031 GN=NARF PE=3 SV=3 CANONICAL=E1BYV6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIC0-1", "url": "https://www.uniprot.org/uniprotkb/E1BYV6/entry#A0A8V1AIC0-1", "sequence": { "sequence": "MKCENCTKKECSKKQKNDDAQSTSVDVLSSNDDFEEKNEFFTLANAKILLSDCLACDNCMTSEEGARVFQQNQKEFFRILNLNKKCDTSKHKVLAVSICPQSLPYFAAKFSLSVNDAAKRLCGFLKSLGVHYVFDTTIAADFSILESQREFVQRYQRRNQEEHALPMFASACPGWIRYAERVLTNLVTPHICTAKSPQQIMGSLVKGYFARQQNLSPEKIFHVVVAPCYDKKLEALREDFYTALYNSQEVDCVLTSGEIVQIMEQKNVSMKDVTEVAVDSLFGEIKEGDVVRHDGKRSDGYLEHIFKHAAKELFGMDVKEITYKALKNKDFQEVTLEKDGETVLRFAAAYGFRNIQNMVLKLKKGKFLYHFVEVLACPGGCLNGKGQTQTEDGKPDKALLSQMEDVYAAIPVRLPEANVYVQKMYQDWLEGMDSRKVQETLHTKYSAVNQTASNLDIKWKGVQNHGKTHTQPKSP", "length": 475, "header": "tr|A0A8V1AIC0-1|E1BYV6_CHICK Computationally mapped isoform of Nuclear prelamin A recognition factor OS=Gallus gallus OX=9031 GN=NARF PE=3 SV=1 CANONICAL=E1BYV6-1" }, "locus": { "chromosome": "18", "start_pos": 4118318, "end_pos": 4104657, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070442.1", "url": "https://www.ensembl.org/id/ENSGALT00010070442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043133.1", "url": "https://www.ensembl.org/id/ENSGALP00010043133.1" } ] } }, { "isoform_ac": "E1BYV6-1", "url": "https://www.uniprot.org/uniprotkb/E1BYV6/entry#E1BYV6-1", "sequence": { "sequence": "MKCENCTKKECSKKQKNDDAQSTSVDVLSSNDDFEEKNEFFTLANAKILLSDCLACDNCMTSEEGARVFQQNQKEFFRILNLNKKCDTSKHKVLAVSICPQSLPYFAAKFSLSVNDAAKRLCGFLKSLGVHYVFDTTIAADFSILESQREFVQRYQRRNQEEHALPMFASACPGWIRYAERVLTNLVTPHICTAKSPQQIMGSLVKGYFARQQNLSPEKIFHVVVAPCYDKKLEALREDFYTALYNSQEVDCVLTSGEIVQIMEQKNVSMKDVTEVAVDSLFGEIKEGDVVRHDGKRSDGYLEHIFKHAAKELFGMDVKEITYKALKNKDFQEVTLEKDGETVLRFAAAYGFRNIQNMVLKLKKGKFLYHFVEVLACPGGCLNGKGQTQTEDGKPDKALLSQMEDVYAAIPVRLPEANVYVQKMYQDWLEGMDSRKVQETLHTKYSAVNQTASNLDIKW", "length": 459, "header": "tr|E1BYV6-1|E1BYV6_CHICK Isoform 1 of Nuclear prelamin A recognition factor OS=Gallus gallus OX=9031 GN=NARF PE=3 SV=3 CANONICAL=E1BYV6-1" }, "locus": { "chromosome": "18", "start_pos": 4118318, "end_pos": 4106502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070443.1", "url": "https://www.ensembl.org/id/ENSGALT00010070443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043134.1", "url": "https://www.ensembl.org/id/ENSGALP00010043134.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417341", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AA04-1", "protein_name": "Nuclear prelamin A recognition factor", "gene_name": "NARF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKCEHCTRKECSKKTKTDDQENASVEVPSPAPESGEEKCDASEHRVLAVSVCPQSLPYFAAKFSLSVTDASRRLCGFLKSLGVHYVFDATIAADFSILESQKEFVRRFHQHSEEEPALPMLTSACPGWVRYAERVLGHPVTPHLCTARSPQQIMGSLVKDYFARRQDLSADRIFHVIVAPCYDRKLEALQEDVPTASPGFRGTDCVLTSGEIAQMMEQSDLSVRDAALDTLFGDVREEVRRHDGASSDGCLAHIFRHAAKELFDEDVGELTYRALRNRDFQEVTLEKSGKVLLRFAAAYGFRNIQNVVLKLKRGRFPYHFVEVLACAGGCLNGRGQAQTEDGRADRALLQRMRGVHAAGPGRTPETSAHVQDLYREWLDGADAPRARGTLHTAHQGPGRPADGRDIKW", "length": 408 }, "evidence": [ { "id": "E1BYV6", "url": "https://omabrowser.org/oma/group/E1BYV6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LV62-1", "protein_name": "Nuclear prelamin A recognition factor", "gene_name": "Narf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKCEHCTRKECSKKSKTDDQENVSIDTSSPAQEKEEKGEFHKLADAKIFLSDCLACDSCVTVEEGVQLSQQSAKDFFHVLNLNKKCDTSKHRVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKSLGVHYVFDTTIAADFSILESQKEFVRRYHRHSEEQRELPMLTSACPGWVRYAERVLGRPVIPHLCTAKSPQQIMGSLVKDYFARQQNLSPEKIFHVVVAPCYDKKLEALREGLSTTLNGARGTDCVLTSGEIAQIMEQSDLSVKDTAVDTLFGDVKEEVAVWRHDGVSSDGHLAHVFRHAAKELFGEHIEEINYRALRNKDFHEVTLEKNGEVLLRFAAAYGFRNIQNMILKLKKGKFPYHFVEVLACPRGCLNGRGQAQTEDGHTDRALLQQMEGIYSGIPVRPPESSAHVEELYQQWLEGTESPKVQEVLHTTYQSLEPCTDSLDMKW", "length": 457 }, "evidence": [ { "id": "E1BYV6", "url": "https://omabrowser.org/oma/group/E1BYV6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2YDU6-1", "protein_name": "Nuclear prelamin A recognition factor", "gene_name": "Narf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKCEHCTRKECSKKSKTDDQENVSVDVPSPAQENEEKGEFHKLADAKIFLSDCLACDSCVTVEEGVQLSQQSAKDFFHVLNLNKRCDTSKHKVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKSLGVHYVFDTTIAADFSILESQKEFVRRYHQHSEEQRELPMLTSACPGWVRYAERVLGRPIIPYLCTAKSPQQVMGSLVKDYFARQQSLAPEKIFHIVVAPCYDKKLEALREGLSPTLNGARGTDCVLTSGEIAQIMEQSDLSVKDIAVDTLFGDVKEMAVRRHDGVSSDGHLAHVFRHAAKELFGEHVEEITYRALRNKDFHEVTLEKNGEVLLRFAAAYGFRNIQNMIMKLKKGKFPYHFVEVLACPRGCLNGRGQAQTEDGHTDRALLQQMEGIYSGIPVWPPESSTHVQELYQEWLEGTESPKVQEVLHTSYQSLEPCTDSLDIKW", "length": 456 }, "evidence": [ { "id": "E1BYV6", "url": "https://omabrowser.org/oma/group/E1BYV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DHP6-1", "protein_name": "Nuclear prelamin A recognition factor", "gene_name": "narf", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEVKIGRKKEKCENCTKQCNKKQSDESINSLQEKGVASGEVRESTSVQQVLLSACLSCDGCISEDEGKRISQQNLDEINHVLALNKKCDTSKHKILVVSVCPQSVPFFAVKFQLDVSAAAQKLCGFLKSVGVHYVFDTTIAASFSILESQREFVQRYRRKHHDANAMPMFTSSCPGWIRYAERVLGSVVTPHICTARSPQQIMGSLVKNFFARQQKLTPEQVFHVVVAPCFDKKLEAVRDEFYNSILESRDVDCVLTSGEILHLMEQSKVTVEEVDSAPLDHVIGEISDSGLTRHDGRGSEGFLEHIFKHAAKEIFGLDVQDIVYKTLRNRDFQEVALERDGETLLQFAAVYGFRNIQTLVHRMRKGKVPYQLIEVLSCPGGCLSGRGQAEGEGGRPDRTLVQQMEEHYSSLPVRLPETNPEVQRLYQDWLDGHDSPHAQQSLHTQYKDHTHLPAHITNPDIQW", "length": 465 }, "evidence": [ { "id": "E1BYV6", "url": "https://omabrowser.org/oma/group/E1BYV6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CYQ7-1", "protein_name": "Nuclear prelamin A recognition factor", "gene_name": "Narf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCEHCTRKECSKKSKTDDQENVSSDGAQPSDGASPAKESEEKGEFHKLADAKIFLSDCLACDSCVTVEEGVQLSQQSAKDFLHVLNLNKRCDTSKHRVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKSLGVHYVFDTTIAADFSILESQKEFVRRYHQHSEEQRELPMLTSACPGWVRYAERVLGRPIIPYLCTAKSPQQVMGSLVKDYFARQQNLSPEKIFHVVVAPCYDKKLEALREGLSTTLNGARGTDCVLTSGEIAQIMEQSDLSVKDIAVDTLFGDMKEVAVQRHDGVSSDGHLAHVFRHAAKELFGEHVEEITYRALRNKDFHEVTLEKNGEVLLRFAAAYGFRNIQNMIQKLKKGKLPYHFVEVLACPRGCLNGRGQAQTEDGHTDRALLQQMEGIYSGIPVRPPESSTHVQELYQEWLEGTESPKVQEVLHTSYQSLEPCTDGLDIKW", "length": 462 }, "evidence": [ { "id": "E1BYV6", "url": "https://omabrowser.org/oma/group/E1BYV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHQ1-1", "protein_name": "Nuclear prelamin A recognition factor", "gene_name": "NARF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKCEHCTRKECSKKTKTDDQENVSADAPSPAQENGEKGEFHKLADAKIFLSDCLACDSCMTAEEGVQLSQQNAKDFFRVLNLNKKCDTSKHKVLVVSVCPQSLPYFAAKFNLSVTDASRRLCGFLKSLGVHYVFDTTIAADFSILESQKEFVRRYRQHSEEERTLPMLTSACPGWVRYAERVLGRPITAHLCTAKSPQQVMGSLVKDYFARQQNLSPEKIFHVIVAPCYDKKLEALQESLPPALHGSRGADCVLTSGEIAQIMEQGDLSVRDAAVDTLFGDLKEDKVTRHDGASSDGHLAHIFRHAAKELFNEDVEEVTYRALRNKDFQEVTLEKNGEVVLRFAAAYGFRNIQNMILKLKKGKFPFHFVEVLACAGGCLNGRGQAQTPDGHADKALLRQMEGIYADIPVRRPESSAHVQELYQEWLEGINSPKAREVLHTTYQSQERGTHSLDIKW", "length": 456 }, "evidence": [ { "id": "E1BYV6", "url": "https://omabrowser.org/oma/group/E1BYV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BYV6", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BYV6", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" } ], "pmid": "" }, { "name": "lamin filament", "id": "GO:0005638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005638", "evidence": [ { "database": "UniProtKB", "id": "E1BYV6", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BYV6", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lamin binding", "id": "GO:0005521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005521", "evidence": [ { "database": "UniProtKB", "id": "E1BYV6", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BYV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYV6" }, { "id": "SM00902", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00902" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Iron hydrogenase small subunit", "eco_id": "ECO_0000259", "start_pos": 393, "end_pos": 449, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMI5-1", "uniprot_ac": "A0A8V1AMI5", "uniprot_id": "A0A8V1AMI5_CHICK", "mass": { "chemical_mass": 124187.0, "monoisotopic_mass": 124187.0 }, "refseq": { "ac": "XP_004946313", "name": "putative sodium-coupled neutral amino acid transporter 10 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946313" }, "gene_names": [ { "name": "SLC38A10", "type": "recommended", "evidence": [ { "id": "A0A8V1AMI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" } ] }, { "name": "SLC38A10", "type": "synonym", "evidence": [ { "id": "XP_004946313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946313" } ] } ], "protein_names": [ { "name": "Solute carrier family 38 member 10", "type": "synonym", "evidence": [ { "id": "A0A8V1AMI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5/entry#names_and_taxonomy" } ] }, { "name": "putative sodium-coupled neutral amino acid transporter 10 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004946313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946313" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946313.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC38A10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5", "locus": { "chromosome": "18", "start_pos": 9888914, "end_pos": 9852092, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029525", "url": "https://www.ensembl.org/id/ENSGALG00010029525" } ] } } ], "crossref": [ { "id": "A0A8V1AMI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "422070", "url": "https://www.ncbi.nlm.nih.gov/gene/422070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422070", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422070", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AIT9", "url": "https://www.orthodb.org/?gene=A0A8V1AIT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKM1", "url": "https://www.orthodb.org/?gene=A0A8V1AKM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMI5", "url": "https://www.orthodb.org/?gene=A0A8V1AMI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAGSNWGLIMNVVNSIVGVSVLTVPFCFRQCGIVLGALLLIFCSWMTHQSCMFLVKSANLSKRRTYPGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLLGFQVSGSFRIVLLFAVSLCIVLPLSLQRNMMASIQSFSAMALIFYTVFMFVIVLSSFKHGLFSGQWLQKVSYTRWEGIFRCIPIFGMSFACQSQVLPTYDSLDEPSVKIMSSIFASSLNVVTTFYITVGFFGYVSYTEAIAGNVLMNFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKALTLAVVFGTMIGGIMIPNVETVLGLTGATMGSLICFICPALIYKKIHKNALCSQIILWIGLGMLIISTYTTLSATEDTPVKAEVVGMEHLEREEDRIDQDAVKLPEQNPAVEEAEDDRHKPKLLDEKEEMEQPQIKVPMEVPERDEERGKPEEKVQLDRPDPGIALPMGEAHRHEPPVPHDEVVVDMGREREDSAENKQVLGGDEGNAPKAAPREPAELHPQKEAQGKEVMAENHAWGGTEKPVKNLKNAPEVSVPKDGRPPYKEQEPGRAAPDAKARTAVLAGERNAEAAGDGEKMKLQFPGKAEEVVKSLEKEAEPGEKPELPLPEHVEPAEPQQLEQRESRNGEDRQAENAENKLEEAEQAKMLDHAVLLQVIKEQQVQQKQLLDQQAKLLAVIEEQHKEIHQQRQEEGGEEKPKQAEMQQEPAVPLSKSKEEENLGAKQEGAAKPLGKEPPEHPVPGAGRQPAESAEQRRVTAGRLEEAGHRREIPGVPPKERKVPQQEIDRAVRNAAENWDPLHGDAQRVPAARNHLEKKPLAEEAGRGHEAKAGRDVHENSLKAVEAATVPIQREQLGAAKVQGVAGKSLERDSGIDLKAKAVSQVEPKDLALALDFLNKRNVAGSEQHLREHPRAADAEGADKQQPASRGDLASKGQGKEEDPRERVVDVAQDPQGELQGKQRRVVGGLANGAEKKPGPENAAAQKLEKGAAIPEDQKQDHDIKPNRDLKLQVDLDLRRRRRDLLPRQEEEEEAAQGAGVFIGLNPLPDVKVNDLRSALETRLNQVAEGAQQVVHSRQIKQMTEADGSM", "length": 1129, "header": "tr|A0A8V1AMI5-1|A0A8V1AMI5_CHICK Isoform 1 of Solute carrier family 38 member 10 OS=Gallus gallus OX=9031 GN=SLC38A10 PE=1 SV=1 CANONICAL=A0A8V1AMI5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5/entry#A0A8V1AIT9-1", "sequence": { "sequence": "MNLTRAADSPGDEPLSWCESWNHSVWHCPGSSALDFLFLDDSSILHVPGEIGQSQQAQDLPRPGMIGLMLGTCIAFYVVIGDLGSNFFARLLGFQVSGSFRIVLLFAVSLCIVLPLSLQRNMMASIQSFSAMALIFYTVFMFVIVLSSFKHGLFSGQWLQKVSYTRWEGIFRCIPIFGMSFACQSQVLPTYDSLDEPSVKIMSSIFASSLNVVTTFYITVGFFGYVSYTEAIAGNVLMNFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKALTLAVVFGTMIGGIMIPNVETVLGLTGATMGSLICFICPALIYKKIHKNALCSQIILWIGLGMLIISTYTTLSATEDTPVKAEVVGMEHLEREEDRIDQDAVKLPEQNPAVEEAEDDRHKPKLLDEKEEMEQPQIKVPMEVPERDEERGKPEEKVQLDRPDPGIALPMGEAHRHEPPVPHDEVVVDMGREREDSAENKQVLGGDEGNAPKAAPREPAELHPQKEAQGKEVMAENHAWGGTEKPVKNLKNAPEVSVPKDGRPPYKEQEPGRAAPDAKARTAVLAGERNAEAAGDGEKMKLQFPGKAEEVVKSLEKEAEPGEKPELPLPEHVEPAEPQQLEQRESRNGEDRQAENAENKLEEAEQAKMLDHAVLLQVIKEQQVQQKQLLDQQAKLLAVIEEQHKEIHQQRQEEGGEEKPKQAEMQQEPAVPLSKSKEEENLGAKQEGAAKPLGKEPPEHPVPGAGRQPAESAEQRRVTAGRLEEAGHRREIPGVPPKERKVPQQEIDRAVRNAAENWDPLHGDAQRVPAARNHLEKKPLAEEAGRGHEAKAGRDVHENSLKAVEAATVPIQREQLGAAKVQGVAGKSLERDSGIDLKAKAVSQVEPKDLALALDFLNKRNVAGSEQHLREHPRAADAEGADKQQPASRGDLASKGQGKEEDPRERVVDVAQDPQGELQGKQRRVVGGLANGAEKKPGPENAAAQKLEKGAAIPEDQKQDHDIKPNRDLKLQVDLDLRRRRRDLLPRQEEEEEAAQGAGVFIGLNPLPDVKVNDLRSALETRLNQVAEGAQQVVHSRQIKQMTEADGSM", "length": 1105, "header": "tr|A0A8V1AIT9-1|A0A8V1AMI5_CHICK Computationally mapped isoform of Solute carrier family 38 member 10 OS=Gallus gallus OX=9031 GN=SLC38A10 PE=1 SV=1 CANONICAL=A0A8V1AMI5-1" }, "locus": { "chromosome": "18", "start_pos": 9887910, "end_pos": 9859700, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071367.1", "url": "https://www.ensembl.org/id/ENSGALT00010071367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044057.1", "url": "https://www.ensembl.org/id/ENSGALP00010044057.1" } ] } }, { "isoform_ac": "A0A8V1AKM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5/entry#A0A8V1AKM1-1", "sequence": { "sequence": "MCGIVLGALLLIFCSWMTHQSCMFLVKSANLSKRRTYPGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLLGFQVSGSFRIVLLFAVSLCIVLPLSLQRNMMASIQSFSAMALIFYTVFMFVIVLSSFKHGLFSGQWLQKVSYTRWEGIFRCIPIFGMSFACQSQVLPTYDSLDEPSVKIMSSIFASSLNVVTTFYITVGFFGYVSYTEAIAGNVLMNFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKALTLAVVFGTMIGGIMIPNVETVLGLTGATMGSLICFICPALIYKKIHKNALCSQIILWIGLGMLIISTYTTLSATEDTPVKAEVVGMEHLEREEDRIDQDAVKLPEQNPAVEEAEDDRHKPKLLDEKEEMEQPQIKVPMEVPERDEERGKPEEKVQLDRPDPGIALPMGEAHRHEPPVPHDEVVVDMGREREDSAENKQVLGGDEGNAPKAAPREPAELHPQKEAQGKEVMAENHAWGGTEKPVKNLKNAPEVSVPKDGRPPYKEQEPGRAAPDAKARTAVLAGERNAEAAGDGEKMKLQFPGKAEEVVKSLEKEAEPGEKPELPLPEHVEPAEPQQLEQRESRNGEDRQAENAENKLEEAEQAKMLDHAVLLQVIKEQQVQQKQLLDQQAKLLAVIEEQHKEIHQQRQEEGGEEKPKQAEMQQEPAVPLSKSKEEENLGAKQEGAAKPLGKEPPEHPVPGAGRQPAESAEQRRVTAGRLEEAGHRREIPGVPPKERKVPQQEIDRAVRNAAENWDPLHGDAQRVPAARNHLEKKPLAEEAGRGHEAKAGRDVHENSLKAVEAATVPIQREQLGAAKVQGVAGKSLERDSGIDLKAKAVSQVEPKDLALALDFLNKRNVAGSEQHLREHPRAADAEGADKQQPASRGDLASKGQGKEEDPRERVVDVAQDPQGELQGKQRRVVGGLANGAEKKPGPENAAAQKLEKGAAIPEDQKQDHDIKPNRDLKLQVDLDLRRRRRDLLPRQEEEEEAAQGAGVFIGLNPLPDVKVNDLRSALETRLNQVAEGAQQVVHSRQIKQMTEADGSM", "length": 1097, "header": "tr|A0A8V1AKM1-1|A0A8V1AMI5_CHICK Computationally mapped isoform of Solute carrier family 38 member 10 OS=Gallus gallus OX=9031 GN=SLC38A10 PE=1 SV=1 CANONICAL=A0A8V1AMI5-1" }, "locus": { "chromosome": "18", "start_pos": 9887910, "end_pos": 9852809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071369.1", "url": "https://www.ensembl.org/id/ENSGALT00010071369.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044059.1", "url": "https://www.ensembl.org/id/ENSGALP00010044059.1" } ] } }, { "isoform_ac": "A0A8V1AMI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5/entry#A0A8V1AMI5-1", "sequence": { "sequence": "MAAAAGSNWGLIMNVVNSIVGVSVLTVPFCFRQCGIVLGALLLIFCSWMTHQSCMFLVKSANLSKRRTYPGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLLGFQVSGSFRIVLLFAVSLCIVLPLSLQRNMMASIQSFSAMALIFYTVFMFVIVLSSFKHGLFSGQWLQKVSYTRWEGIFRCIPIFGMSFACQSQVLPTYDSLDEPSVKIMSSIFASSLNVVTTFYITVGFFGYVSYTEAIAGNVLMNFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFAAGGYMPPLRFKALTLAVVFGTMIGGIMIPNVETVLGLTGATMGSLICFICPALIYKKIHKNALCSQIILWIGLGMLIISTYTTLSATEDTPVKAEVVGMEHLEREEDRIDQDAVKLPEQNPAVEEAEDDRHKPKLLDEKEEMEQPQIKVPMEVPERDEERGKPEEKVQLDRPDPGIALPMGEAHRHEPPVPHDEVVVDMGREREDSAENKQVLGGDEGNAPKAAPREPAELHPQKEAQGKEVMAENHAWGGTEKPVKNLKNAPEVSVPKDGRPPYKEQEPGRAAPDAKARTAVLAGERNAEAAGDGEKMKLQFPGKAEEVVKSLEKEAEPGEKPELPLPEHVEPAEPQQLEQRESRNGEDRQAENAENKLEEAEQAKMLDHAVLLQVIKEQQVQQKQLLDQQAKLLAVIEEQHKEIHQQRQEEGGEEKPKQAEMQQEPAVPLSKSKEEENLGAKQEGAAKPLGKEPPEHPVPGAGRQPAESAEQRRVTAGRLEEAGHRREIPGVPPKERKVPQQEIDRAVRNAAENWDPLHGDAQRVPAARNHLEKKPLAEEAGRGHEAKAGRDVHENSLKAVEAATVPIQREQLGAAKVQGVAGKSLERDSGIDLKAKAVSQVEPKDLALALDFLNKRNVAGSEQHLREHPRAADAEGADKQQPASRGDLASKGQGKEEDPRERVVDVAQDPQGELQGKQRRVVGGLANGAEKKPGPENAAAQKLEKGAAIPEDQKQDHDIKPNRDLKLQVDLDLRRRRRDLLPRQEEEEEAAQGAGVFIGLNPLPDVKVNDLRSALETRLNQVAEGAQQVVHSRQIKQMTEADGSM", "length": 1129, "header": "tr|A0A8V1AMI5-1|A0A8V1AMI5_CHICK Isoform 1 of Solute carrier family 38 member 10 OS=Gallus gallus OX=9031 GN=SLC38A10 PE=1 SV=1 CANONICAL=A0A8V1AMI5-1" }, "locus": { "chromosome": "18", "start_pos": 9887910, "end_pos": 9859069, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071368.1", "url": "https://www.ensembl.org/id/ENSGALT00010071368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044058.1", "url": "https://www.ensembl.org/id/ENSGALP00010044058.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 799, "start_aa": "Thr", "end_pos": 799, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr799", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422070", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI5" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 391, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 799 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMK9-1", "uniprot_ac": "A0A8V1AMK9", "uniprot_id": "A0A8V1AMK9_CHICK", "mass": { "chemical_mass": 171280.0, "monoisotopic_mass": 171280.0 }, "refseq": { "ac": "XP_001233717", "name": "tyrosine-protein kinase BAZ1B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233717" }, "gene_names": [ { "name": "BAZ1B", "type": "recommended", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "name": "BAZ1B", "type": "synonym", "evidence": [ { "id": "XP_001233717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233717" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase BAZ1B", "type": "recommended", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9/entry#names_and_taxonomy" } ] }, { "name": "Bromodomain adjacent to zinc finger domain protein 1B", "type": "synonym", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9/entry#names_and_taxonomy" } ] }, { "name": "tyrosine-protein kinase BAZ1B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001233717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233717" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_001233717.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233717" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BAZ1B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9", "locus": { "chromosome": "19", "start_pos": 794545, "end_pos": 745493, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029536", "url": "https://www.ensembl.org/id/ENSGALG00010029536" } ] } } ], "crossref": [ { "id": "cd05505", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05505", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15628", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15628", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427819", "url": "https://www.ncbi.nlm.nih.gov/gene/427819", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427819", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427819", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KVCRRKV", "url": "https://omabrowser.org/oma/group/KVCRRKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AIX2", "url": "https://www.orthodb.org/?gene=A0A8V1AIX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMK9", "url": "https://www.orthodb.org/?gene=A0A8V1AMK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46802", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46802", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46802:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46802:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10537", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10537", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5693565", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693565", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AIX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPLLGRKPFPLAKPLPPGEPGERFIIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPIWYEKPVLEIVHHNTVSLEKLVDAAWVEIMTKFAVGEECDFEVGKEKMLPVKVVKIHPLEKVDEEASEKKSEGACDSPSSDKENSSQAAQDNQKESVLKEEDSRRESMNDRARRSPRKLPTSLKKEERKWVPPKFLPHKYDVKLKNEDKIISNVPADSLVRTERPPNKEILRYFIRHNALRAGIGENAPWVVEDELVKKYSLPSKFSDFLLDPHKYMTLNPSTKRKSSGSPDRKPSKKSKTDGSSLSQPLSPTLWCHVHLEKSIIGSPLKMKNSKISKCPKEELEEMMKIMSPGKLDSNFHIPKRSRLGKGSNKSLDKKQRGKRVLNGQKTSGKSKSPGKGLKTPKMKMKQMTLLDMAKGTTKVSRTPRNSGGTPRSSSKPQKLPPAALHLIAYYKENKDREDKKSALSCIISKTARLLSNEDRARLPEDLRGLVQKRYELLEHRKKLATMTEEQRKEYLKKKREKLKEKLKERAKERKEKEMKEKLEKNKRFEDQDLKGKNLPTFKLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLMPDAQYPITAVSLMEALCAEKGGFLYLNRVLVILLQTLLQDEIAEDYAELGMKLSEIPLTLHSASELVRLCLRKSDVQEESEVSDNVDESKDSATFEDNEVQDEFLEKLETSEFFELTPEEKLQILGALCHRILMTYSVQDHVEAKQQASAELWKERLAILKEENDKKRAEKQKRKEMVAKNKENGKDENTTGRNEKKKNEIVKIEHRVEIEADDMISAVKSRRLLAIQAKKEREQQERQMRVRMEKEAEEERIRKHKAAAEKTFQDGIAKAKLVMRRTPVGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFILPHQKKEEAKKDYSSGDKRRSTAADGRTSALHRSAYAADLPAETTAPKQGQNLWFLCDSQKDLDELIDCLHPQGVRESQLKERLEKKYQDITHSMHLARKQNLGLKSCDGNQELLNYLRSDLIEVATRLQKGGLGYVDVTPEFEARVYSLESLKDFGECVIALQAGVIKKFLQGFMAPKQKRRKHQGEDYITKAEEVDEEKKMAEEAKVASAMEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEIPDGEWQCPACQPSTARRSSRGRNYTEDSAEDEGEEGEEASDEQDAEEEEEEEEDYEVAGLKLRPRKAARGKQSTAMYSSRQGRHQRKKQSLHPARGPRQRAAPVNSADIDELVLQTRKTARRQSLELQKCEEILSKLIKYRFSWPFREPVTTEEAEDYCEVISNPMDFQTMQSKCSCGNYRSVQEFLSDMKQVFSNAERYNQNGSHVLSCLEKTEQCLIDMVHKHLPGHTYARRKRKKFSAGCQGLEEQEGDSESEPLEHSRGRRRKK", "length": 1489, "header": "tr|A0A8V1AMK9-1|A0A8V1AMK9_CHICK Isoform 1 of Tyrosine-protein kinase BAZ1B OS=Gallus gallus OX=9031 GN=BAZ1B PE=1 SV=1 CANONICAL=A0A8V1AMK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9/entry#A0A8V1AIX2-1", "sequence": { "sequence": "MAPLLGRKPFPLAKPLPPGEPGERFIIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPIWYEKPVLEIVHHNTVSLEKLVDAAWVEIMTKFAVGEECDFEVGKEKMLPVKVVKIHPLEKVDEEASEKKSEGACDSPSSDKENSSQAAQDNQKESVLKEEDSRRESMNDRARRSPRKLPTSLKKEERKWVPPKFLPHKYDVKLKNEDKIISNVPADSLVRTERPPNKEILRYFIRHNALRAGIGENAPWVVEDELVKKYSLPSKFSDFLLDPHKYMTLNPSTKRKSSGSPDRKPSKKSKTDGSSLSQPLSPTLWCHVHLEKSIIGSPLKMKNSKISKCPKEELEEMMKIMSPGKLDSNFHIPKRSRLGKGSNKSLDKKQRGKRVLNGQKTSGKSKSPGKGLKTPKMKMKQMTLLDMAKGTTKVSRTPRNSGGTPRSSSKPQKLPPAALHLIAYYKENKDREDKKSALSCIISKTARLLSNEDRARLPEDLRGLVQKRYELLEHRKKLATMTEEQRKEYLKKKREKLKEKLKERAKERKEKEMKEKLEKNKRFEDQDLKGKNLPTFKLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLMPDAQYPITAVSLMEALCAEKGGFLYLNRVLVILLQTLLQDEIAEDYAELGMKLSEIPLTLHSASELVRLCLRKSDVQEESEVSDNVDESKDSATFEDNEVQDEFLEKLETSEFFELTPEEKLQILGALCHRILMTYSVQDHVEAKQQASAELWKERLAILKEENDKKRAEKQKRKEMVAKNKENGKDENTTGRNEKKKNEIVKIEHRVEIEADDMISAVKSRRLLAIQAKKEREQQERQMRVRMEKEAEEERIRKHKAAAEKTFQDGIAKAKLVMRRTPVGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFILPHQKKEEAKKDYSSGDKRRSTAADGRTSALHRSAYAADLPAETTAPKQGQNLWFLCDSQKDLDELIDCLHPQGVRESQLKERLEKKYQDITHSMHLARKQNLGLKSCDGNQELLNYLRSDLIEVATRLQKGGLGYVDVTPEFEARVYSLESLKDFGECVIALQAGVIKKFLQGFMAPKQKRRKHQGEDYITKAEEVDEEKKMAEEAKVASAMEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEIPDGEWQCPACQPSTARRSSRGRNYTEDSAEDEGEEGEEASDEQDAEEEEEEEEDYEVAGLKLRPRKAARGKQSTAMYSSRQGRHQRKKQSLHPARGPRQRAAPVNSADIDELVLQTRKTARRQSLELQKCEEILSKLIKYRFSWPFREPVTTEEAEDYCEVISNPMDFQTMQSKCSCGNYRSVQEFLSDMKQVFSNAERYNQNGSHVLSCLEKTEQCLIDMVHKHLPGHTYARRKRKKFSAGCQGLEEQEGDISSNDFVIH", "length": 1482, "header": "tr|A0A8V1AIX2-1|A0A8V1AMK9_CHICK Computationally mapped isoform of Tyrosine-protein kinase BAZ1B OS=Gallus gallus OX=9031 GN=BAZ1B PE=1 SV=1 CANONICAL=A0A8V1AMK9-1" }, "locus": { "chromosome": "19", "start_pos": 792991, "end_pos": 745601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071397.1", "url": "https://www.ensembl.org/id/ENSGALT00010071397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044087.1", "url": "https://www.ensembl.org/id/ENSGALP00010044087.1" } ] } }, { "isoform_ac": "A0A8V1AMK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9/entry#A0A8V1AMK9-1", "sequence": { "sequence": "MAPLLGRKPFPLAKPLPPGEPGERFIIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPIWYEKPVLEIVHHNTVSLEKLVDAAWVEIMTKFAVGEECDFEVGKEKMLPVKVVKIHPLEKVDEEASEKKSEGACDSPSSDKENSSQAAQDNQKESVLKEEDSRRESMNDRARRSPRKLPTSLKKEERKWVPPKFLPHKYDVKLKNEDKIISNVPADSLVRTERPPNKEILRYFIRHNALRAGIGENAPWVVEDELVKKYSLPSKFSDFLLDPHKYMTLNPSTKRKSSGSPDRKPSKKSKTDGSSLSQPLSPTLWCHVHLEKSIIGSPLKMKNSKISKCPKEELEEMMKIMSPGKLDSNFHIPKRSRLGKGSNKSLDKKQRGKRVLNGQKTSGKSKSPGKGLKTPKMKMKQMTLLDMAKGTTKVSRTPRNSGGTPRSSSKPQKLPPAALHLIAYYKENKDREDKKSALSCIISKTARLLSNEDRARLPEDLRGLVQKRYELLEHRKKLATMTEEQRKEYLKKKREKLKEKLKERAKERKEKEMKEKLEKNKRFEDQDLKGKNLPTFKLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLMPDAQYPITAVSLMEALCAEKGGFLYLNRVLVILLQTLLQDEIAEDYAELGMKLSEIPLTLHSASELVRLCLRKSDVQEESEVSDNVDESKDSATFEDNEVQDEFLEKLETSEFFELTPEEKLQILGALCHRILMTYSVQDHVEAKQQASAELWKERLAILKEENDKKRAEKQKRKEMVAKNKENGKDENTTGRNEKKKNEIVKIEHRVEIEADDMISAVKSRRLLAIQAKKEREQQERQMRVRMEKEAEEERIRKHKAAAEKTFQDGIAKAKLVMRRTPVGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFILPHQKKEEAKKDYSSGDKRRSTAADGRTSALHRSAYAADLPAETTAPKQGQNLWFLCDSQKDLDELIDCLHPQGVRESQLKERLEKKYQDITHSMHLARKQNLGLKSCDGNQELLNYLRSDLIEVATRLQKGGLGYVDVTPEFEARVYSLESLKDFGECVIALQAGVIKKFLQGFMAPKQKRRKHQGEDYITKAEEVDEEKKMAEEAKVASAMEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEIPDGEWQCPACQPSTARRSSRGRNYTEDSAEDEGEEGEEASDEQDAEEEEEEEEDYEVAGLKLRPRKAARGKQSTAMYSSRQGRHQRKKQSLHPARGPRQRAAPVNSADIDELVLQTRKTARRQSLELQKCEEILSKLIKYRFSWPFREPVTTEEAEDYCEVISNPMDFQTMQSKCSCGNYRSVQEFLSDMKQVFSNAERYNQNGSHVLSCLEKTEQCLIDMVHKHLPGHTYARRKRKKFSAGCQGLEEQEGDSESEPLEHSRGRRRKK", "length": 1489, "header": "tr|A0A8V1AMK9-1|A0A8V1AMK9_CHICK Isoform 1 of Tyrosine-protein kinase BAZ1B OS=Gallus gallus OX=9031 GN=BAZ1B PE=1 SV=1 CANONICAL=A0A8V1AMK9-1" }, "locus": { "chromosome": "19", "start_pos": 792797, "end_pos": 745601, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071398.1", "url": "https://www.ensembl.org/id/ENSGALT00010071398.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044088.1", "url": "https://www.ensembl.org/id/ENSGALP00010044088.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:427819", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427819", "resource": "KEGG Pathway" }, { "id": "R-GGA-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" }, { "id": "R-GGA-5693565", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693565", "resource": "Reactome", "description": "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ALC2-1", "protein_name": "Tyrosine-protein kinase BAZ1B", "gene_name": "Baz1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPNWYEKLVLEMVHHNTASLEKLVDSAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEAAEKKSDGTCDSPSSDKENSSQMAQDHQKETVVKEDGGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQSEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKPKRDNSSLSSPLNPKLWCHVHLEKSLNGPPLKVKNSKNSKSPEEHLEEVMKIMSPNKLHSFHIPKKGPSTKKPGKHSDKPLKAKGRGKGILNGQKSTGNSKSPSKCVKTPKTKMKQMTLLDMAKGTQKMTRTPRSSGGVPRSSGKPHKHLPPAALHLIAYYKENKDKEDKKSALSCVISKTARLLSSEDRARLPEELRALVQKRYELLEHKKRWASMSEEQRKEYLKKKRQELKERLREKAKERREKEMLERLEKQKRYEDQELGGRNLPTFRLVDTPEGLPNTLFGDVALVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRCDVQEDSEGSDTDDNKDSTPFEDNEVQDEFLEKLETSEFFELTSEEKLRILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENVLGKVDRKKEIVKIENQVEVEADDMISAVKSRRLLSMQAKRKREIQERETKVRLEREAEEERVRKHKAAAEKAFQEGIAKAKLVLRRTPIGTDRNHNRYWLFSNEVPGLFIEKGWVHNSIDYRFKHHRKDHNNLPDDDYCPRSKKANLGKNASVNAHLGSALEAVETTVPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQEITHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTSEFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKKRKLQSEDSTKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPPTARRNSRGRNYTEESTSEDSEGDESGDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKQSVIPAARPGRPPGKKSHAARRSRPKDDTEVDELVLQTKRSSRRQSLELQKCEEILHKLVKYRFSWPFREPVTRDEAEDYYDVIDHPMDFQTMQNKCSCGNYRSVQEFLTDVKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHPYVRRKRRKFPDRLADDEGDSDSESVGQSRGRRQKK", "length": 1476 }, "evidence": [ { "id": "A0A8V1AMK9", "url": "https://omabrowser.org/oma/group/A0A8V1AMK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B6X6-1", "protein_name": "Tyrosine-protein kinase BAZ1B", "gene_name": "BAZ1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPLLGRKPFPLVKPLPGEEPLFTIAHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEECDFEVGKEKMLKVRIVKIHPLEKVDEEATEKKSDGSCDSPSSDKENSSQIAQDHQKKEAVGKEEEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQDEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLNGSPLKVKNSKNSKSPEEHLEEVMKMMSPNKLHANFHIPKKGPPGKKSGKHSDKPLKAKGRGKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKVTRAPRNSGGTPRSSSKPHKHLPPAALHLIAYYKENKDREDKKSALSCVISKTARLLSSEDRARLPEELRSIVQKRFELLEHKKRWASMSEEQRKEYLKKKREELKEKLKEKAKERREKEMLERLEKQKRYEDQELTGKTLPTFKLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSAEKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRKSDVQEESEGSDADDNKDSASFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENGLGKADRKKEVVKFEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLEREAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFSHHRKDHADSPDEDYCPRSKKANLGKNVSTNMHHGPAAEIAVETTVPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMAEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESNEEEEEEEEEEEEDYEVAGLRLRPRKTVRGKQGVIPPTARPGRRPGKKPHPARRARPKAPPADDMEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDIITHPMDFQTMQSKCSCGGYRSVQEFLADLKQVFTNAELYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEPVGQSRGRRQKK", "length": 1482 }, "evidence": [ { "id": "A0A8V1AMK9", "url": "https://omabrowser.org/oma/group/A0A8V1AMK9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LCE6-1", "protein_name": "Tyrosine-protein kinase BAZ1B", "gene_name": "BAZ1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPLLGRKPFPLVKPLPGEEPLFTIAHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEECDFEVGKEKMLKVRIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHPKKEAIVKENEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLNGSPLKVKNSKNSKSPEEHLEEVMKVMSPNKLHGNFHIPKKGPPGKKSGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRSSSKPHKHLPPAALHLIAYYKENKDREDKKSALSCVISKTARLLSSEDRARLPEELRGIVQKRFELLEHKKRWASMSEEQRKEYLKKKREELKEKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSAEKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRKSDVQEESEGSDTDDNKDSAPFDDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENGLGKADRKKEVVKFETQVDIEADDMISAVKSRRLLAIQAKKEREIQEREMKVKLEREAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFSNHRKDRAASPDEDYCPRTKKANLGKNVNMNTQHGPATEIAVETTVPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMAEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYAVPDGEWQCPACQPATARRNSRGRNYTEESSSEDSEDDESEEEEEEGEEEEEEEDYEVAGLRLRPRKTVRGRQGVVPPAARPGRRPGKKPLPTRRSRPKPPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKLVKYRFSWPFREPVTRDEAEDYYDVIAHPMDFQTMQNKCSCGSYRSVQEFLADMKQVFTNAELYNCRGSHVLNCTVKTEQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEPVGQSRGRRQKK", "length": 1483 }, "evidence": [ { "id": "A0A8V1AMK9", "url": "https://omabrowser.org/oma/group/A0A8V1AMK9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9UIG0-1", "protein_name": "Tyrosine-protein kinase BAZ1B", "gene_name": "BAZ1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPAWYEKLVLEMVHHNTASLEKLVDTAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEIVRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRKNTGSPDRKPSKKSKTDNSSLSSPLNPKLWCHVHLKKSLSGSPLKVKNSKNSKSPEEHLEEMMKMMSPNKLHTNFHIPKKGPPAKKPGKHSDKPLKAKGRSKGILNGQKSTGNSKSPKKGLKTPKTKMKQMTLLDMAKGTQKMTRAPRNSGGTPRTSSKPHKHLPPAALHLIAYYKENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKKKLKEKAKERREKEMLERLEKQKRYEDQELTGKNLPAFRLVDTPEGLPNTLFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFEDNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKERLAVLKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKKEIVKFEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEKAFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIEKGWVHDSIDYRFNHHCKDHTVSGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNCLHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKRRKLQSEDSAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQSLELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQEFLTDMKQVFTNAEVYNCRGSHVLSCMVKTEQCLVALLHKHLPGHPYVRRKRKKFPDRLAEDEGDSEPEAVGQSRGRRQKK", "length": 1483 }, "evidence": [ { "id": "A0A8V1AMK9", "url": "https://omabrowser.org/oma/group/A0A8V1AMK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z277-1", "protein_name": "Tyrosine-protein kinase BAZ1B", "gene_name": "Baz1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPNWYEKLVLEMVHHNTASLEKLVDSAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEAVEKKSDGACDSPSSDKENSSQMAQDLQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRRNTGSPDRKPSKKPKRDSSSLSSPLNPKLWCHVHLEKSLNGPPLKVKNSKNSKSPEEHLEGVMKIMSPNNNKLHSFHIPKKGPAAKKPGKHSDKPLKAKGRGKGILNGQKSTGNSKSPSKCVKTPKTKMKQMTLLDMAKGTQKMTRTPRSSGGVPRSSGKPHKHLPPAALHLIAYYKENKDKEDKKSALSCVISKTARLLSNEDRARLPEELRALVQKRYELLEHKKRWASMSEEQRKEYLKKKRQELKERLREKAKERREREMLERLEKQKRFEDQELGGRNLPAFRLVDTPEGLPNTLFGDVALVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRCDVQEDSEGSETDDNKDSTPFEDNEVQDEFLEKLETSEFFELTSEEKLRILTALCHRILMTYSVQDHMETRQQVSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENVLGKVDRKKEIVKIEQQVEVEADDMISAVKSRRLLSMQAKRKREIQERETKVRLEREAEEERMRKHKAAAEKAFQEGIAKAKLVLRRTPIGTDRNHNRYWLFSNEVPGLFIEKGWVHNSIDYRFKHHRKDHSNLPDDDYCPRSKKANLGKNASVNAHHGPALEAVETTVPKQGQNLWFLCDSQKELDELLSCLHPQGIRESQLKERLEKRYQEITHSIYLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTSEFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKKRKLQSEDSTKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPPTARRNSRGRNYTEESTSEGSEGDESGEEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKQSVIPAARPGRPPGKKSHPARRSRPKDDPEVDDLVLQTKRISRRQSLELQKCEDILHKLVKYRFSWPFREPVTRDEAEDYYDVIEHPMDFQTIQNKCSCGNYRSVQEFLTDMKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHPYVRRKRRKFPDRLADDEGDSDSESVGQSRGRRQKK", "length": 1479 }, "evidence": [ { "id": "A0A8V1AMK9", "url": "https://omabrowser.org/oma/group/A0A8V1AMK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "histone H2AXY142 kinase activity", "id": "GO:0140801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140801", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "histone kinase activity", "id": "GO:0035173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035173", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "post-translational protein modification", "id": "GO:0043687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043687", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "negative regulation of mitotic chromosome condensation", "id": "GO:1905213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "WICH complex", "id": "GO:0090535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090535", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "nuclear replication fork", "id": "GO:0043596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "condensed chromosome", "id": "GO:0000793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1244, "end_pos": 1246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1424, "end_pos": 1426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADF0-1", "F1N9Y5-1", "A0A8V0XQG0-1", "A0A8V0Y9A0-1", "A0A8V1AFM7-1", "A0A8V0Z0R8-1", "A0A8V0Z4B2-1", "A0A8V0ZBN6-1", "P09324-1", "A0A8V0XHW1-1", "A0A8V0YW12-1", "A0A8V0YUJ4-1", "A0A8V0ZSN8-1", "F1NVF2-1", "A0A8V1AKW4-1", "A0A8V0XB17-1", "A0A8V0ZC34-1", "A0A8V0YYC1-1", "A0A8V0ZND5-1", "A0A8V1ACF7-1", "A0A8V0ZP30-1", "E1BTE1-1", "Q07497-1", "A0A8V0X6E7-1", "F1NCL8-1", "A0A8V0XNF4-1", "A0A8V0XN86-1", "A0A8V0YEV0-1", "A0A8V0XQ80-1", "A0A8V0XZ82-1", "A0A8V0YZE5-1", "A0A8V0YYZ7-1", "A0A8V0YCV8-1", "A0A8V0YGR1-1", "A0A8V0YNY4-1", "A0A8V0YXM5-1", "A0A8V0YXZ9-1", "A0A3Q2UKD3-1", "A0A8V0YIT6-1", "A0A8V0YIV6-1", "R4GJW5-1", "A0A8V1A3N1-1", "A0A8V1A9R2-1", "A0A8V0ZE65-1", "A0A8V0ZER1-1", "A0A8V0ZXS7-1", "A0A8V1A7N1-1", "H9KZZ1-1", "F1NQL9-1", "A0A8V1ABP4-1", "F1NZY8-1", "Q02977-1", "A0A1D5PD64-1", "A0A8V0ZDU6-1", "A0A3Q2U1T2-1", "R4GJB8-1", "A0A3Q2U639-1", "A0A8V0X5W9-1", "E1C7Z1-1", "A0A8V0Y7Y3-1", "Q5ZIU3-1", "A0A8V0YPR4-1", "A0A8V0YT43-1", "A0A8V0Z3S3-1", "A0A8V0YJJ1-1", "A0A8V0YKP8-1", "A0A8V0YZ74-1", "A0A8V0ZWV8-1", "A0A8V1A069-1", "A0A8V1A7E0-1", "A0A8V1AEL3-1", "E1BTT3-1", "F1N996-1", "H9KZZ2-1", "E1C2C8-1", "Q05876-1", "Q90891-1", "O42422-1", "P00523-1", "P08941-1", "P13387-1", "P18460-1", "P18461-1", "P21804-1", "P28693-1", "P29318-1", "P42683-1", "P54755-1", "Q00944-1", "Q07494-1", "Q07496-1", "Q07498-1", "Q08156-1", "Q6XUX0-1", "Q75R65-1", "Q8AXY6-1", "Q8JH64-1", "Q8QHL3-1", "Q91009-1", "Q91044-1", "Q91987-1", "Q98949-1", "Q9PUF6-1", "F1NW21-1", "A0A8V0YLC3-1", "A0A8V0Z7L6-1", "F1NJX6-1", "A0A8V0YUC4-1", "F1NUX4-1", "A0A8V1A2E6-1", "E1BX69-1", "A0A8V0XPF0-1", "A0A8V0XFC9-1", "A0A8V0XBZ6-1", "A0A8V0ZRU7-1", "A0A8V0ZXD3-1", "A0A8V0YYI3-1", "A0A8V0YWW2-1", "A0A8V0YZP9-1", "A0A8V0YRJ8-1", "F1NLR7-1", "A0A8V0XCY6-1", "A0A8V1AMK9-1", "A0A8V0Z189-1", "P41239-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] }, { "id": "R-GGA-5250930", "name": "B-WICH recruits histone acetyltransferases", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6X9-1", "A0A8V1AMK9-1", "A0A8V0ZUQ0-1", "A0A8V0YJ98-1", "A0A8V0Z9Q2-1", "A0A8V0ZTT2-1", "A0A8V0ZAD3-1" ], "evidence": [ { "id": "R-GGA-5250930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250930" } ] }, { "id": "R-GGA-5250938", "name": "B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X6X9-1", "A0A8V1AMK9-1", "A0A8V0ZUQ0-1", "A0A8V0YJ98-1", "A0A8V0Z9Q2-1", "A0A8V0ZTT2-1", "A0A8V0ZAD3-1" ], "evidence": [ { "id": "R-GGA-5250938", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250938" } ] }, { "id": "R-GGA-5683930", "name": "WICH phosphorylates H2AFX on Y142", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AMK9-1" ], "evidence": [ { "id": "R-GGA-5683930", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5683930" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A3Q2U1T2", "gene_name": "BLK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U1T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U1T2" } ] } ] }, { "uniprot_ac": "A0A3Q2U639", "gene_name": "FYN", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3Q2U639", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U639" } ] } ] }, { "uniprot_ac": "A0A3Q2UKD3", "gene_name": "TEK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A3Q2UKD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UKD3" } ] } ] }, { "uniprot_ac": "A0A8V0X5W9", "gene_name": "TYK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5W9" } ] } ] }, { "uniprot_ac": "A0A8V0X6E7", "gene_name": "FES", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6E7", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z189" } ] } ] }, { "uniprot_ac": "A0A8V0Z3S3", "gene_name": "ALK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S3" } ] } ] }, { "uniprot_ac": "A0A8V0Z4B2", "gene_name": "MERTK", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0Z4B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B2" } ] } ] }, { 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[ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0ZAD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD3" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "A0A8V0ZAD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD3" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZC34", "gene_name": "AXL", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC34" } ] } ] }, { "uniprot_ac": "A0A8V0ZDU6", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZDU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZE65", "gene_name": "NTRK3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", 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"activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3N1" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7N1", "gene_name": "ERBB3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1A7N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7N1" } ] } ] }, { "uniprot_ac": "A0A8V1A9R2", "gene_name": "JAK3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1A9R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9R2" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ACF7", "gene_name": "ABL1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1ACF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF7" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1AEL3", "gene_name": "ZAP70", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AEL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL3" } ] } ] }, { "uniprot_ac": "A0A8V1AFM7", "gene_name": "INSR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V1AFM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFM7" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AMK9", "gene_name": "BAZ1B", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V1AMK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK9" } ] } ] }, { "uniprot_ac": "E1BTE1", "gene_name": "WEE2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE1" } ] } ] }, { "uniprot_ac": "E1BTT3", "gene_name": "BMX", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1BTT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTT3" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1C2C8", "gene_name": "MATK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C2C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2C8" } ] } ] }, { "uniprot_ac": "E1C7Z1", "gene_name": "FER", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E1C7Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C7Z1" } ] } ] }, { "uniprot_ac": "F1N996", "gene_name": "PTK6", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N996" } ] } ] }, { "uniprot_ac": "F1N9Y5", "gene_name": "SYK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1N9Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9Y5" } ] } ] }, { "uniprot_ac": "F1NCL8", "gene_name": "FGFR4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NCL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCL8" } ] } ] }, { "uniprot_ac": "F1NJX6", "gene_name": "EPHA3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NJX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJX6" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NQL9", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQL9" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1NW21", "gene_name": "KDR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1NW21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NW21" } ] } ] }, { "uniprot_ac": "F1NZY8", "gene_name": "TEC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "F1NZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZY8" } ] } ] }, { "uniprot_ac": "H9KZZ1", "gene_name": "NTRK1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ1" } ] } ] }, { "uniprot_ac": "H9KZZ2", "gene_name": "INSRR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "H9KZZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/H9KZZ2" } ] } ] }, { "uniprot_ac": "O42422", "gene_name": "EPHA7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "O42422", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42422" } ] } ] }, { "uniprot_ac": "P00523", "gene_name": "SRC", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P00523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P00523" } ] } ] }, { "uniprot_ac": "P08941", "gene_name": "ROS1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08941", "database": 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"https://www.ncbi.nlm.nih.gov/protein/XP_040543014" } ] } ], "protein_names": [ { "name": "calcium/calmodulin-dependent protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.17", "type": "synonym", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2/entry#names_and_taxonomy" } ] }, { "name": "calcium/calmodulin-dependent protein kinase kinase 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040543014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543014" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052591.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040543014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543014" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAMKK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2", "locus": { "chromosome": "19", "start_pos": 3898644, "end_pos": 3812397, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029238", "url": "https://www.ensembl.org/id/ENSGALG00010029238" } ] } } ], "crossref": [ { "id": "A0A8V1AMQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001617", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001617", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771003", "url": "https://www.ncbi.nlm.nih.gov/gene/771003", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040543014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AIX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKZ8", "url": "https://www.uniprot.org/uniprotkb/F1NKZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKZ8-1", "url": "https://www.uniprot.org/uniprotkb/F1NKZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDSPTDVVGEDSDTGFQDTQAELAERVAAIDVAAHPNRSDQNGEDITEENDTVFSDNVKDIQRNGVNSDVETNEFLLSQQSDNAQSGHASKKPLARPVLSSRKLSLQERSSGSHLASSNTPGFGHYATGPSPRIIRRPTIESNRVSISDAEDCVQLNQYKLQSEIGKGSYGVVKLAYNKDDDKYYAMKVLSKKKLLKQYGFPRRPPPRGSKTSTGEHSKTMAPLDRVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYMVFDLLRKGAVMEVPSDKPFSEDQARLYFRDIVLGIEYLHYQKIIHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDTGKSFSGKALDVWAMGITLYCFVYGKCPFIDEYILGLHNKIKSKPVEFPEESQISDELKELILRMLDKNPETRITVPEIKVHPWLTKGGEEPLPLEEEHCTVVEVTEEEVKNSVKTIPSLPAVILVKAMLRKRSFGNPFEVQTRREERSMSAPGNLLMACVQCCLLSKAVTGISFLARSPPWKTTS", "length": 542, "header": "tr|A0A8V1AMQ2-1|A0A8V1AMQ2_CHICK Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMKK1 PE=4 SV=1 CANONICAL=A0A8V1AMQ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AIX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2/entry#A0A8V1AIX8-1", "sequence": { "sequence": "MEDSPTDVVGEDSDTGFQDTQAELAERVAAIDVAAHPNRSDQNGEDITEENDTVFSDNVKDIQRNGVNSDVETNEFLLSQQSDNAQSGHASKKPLARPVLSSRKLSLQERSSGSHLASSNTPGFGHYATGPSPRIIRRPTIESNRVSISDAEDCVQLNQYKLQSEIGKGSYGVVKLAYNKDDDKYYANDCSLRVALMSRHL", "length": 201, "header": "tr|A0A8V1AIX8-1|A0A8V1AMQ2_CHICK Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMKK1 PE=4 SV=1 CANONICAL=A0A8V1AMQ2-1" }, "locus": { "chromosome": "19", "start_pos": 3861477, "end_pos": 3849648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070666.1", "url": "https://www.ensembl.org/id/ENSGALT00010070666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043357.1", "url": "https://www.ensembl.org/id/ENSGALP00010043357.1" } ] } }, { "isoform_ac": "A0A8V1AMQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2/entry#A0A8V1AMQ2-1", "sequence": { "sequence": "MEDSPTDVVGEDSDTGFQDTQAELAERVAAIDVAAHPNRSDQNGEDITEENDTVFSDNVKDIQRNGVNSDVETNEFLLSQQSDNAQSGHASKKPLARPVLSSRKLSLQERSSGSHLASSNTPGFGHYATGPSPRIIRRPTIESNRVSISDAEDCVQLNQYKLQSEIGKGSYGVVKLAYNKDDDKYYAMKVLSKKKLLKQYGFPRRPPPRGSKTSTGEHSKTMAPLDRVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYMVFDLLRKGAVMEVPSDKPFSEDQARLYFRDIVLGIEYLHYQKIIHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDTGKSFSGKALDVWAMGITLYCFVYGKCPFIDEYILGLHNKIKSKPVEFPEESQISDELKELILRMLDKNPETRITVPEIKVHPWLTKGGEEPLPLEEEHCTVVEVTEEEVKNSVKTIPSLPAVILVKAMLRKRSFGNPFEVQTRREERSMSAPGNLLMACVQCCLLSKAVTGISFLARSPPWKTTS", "length": 542, "header": "tr|A0A8V1AMQ2-1|A0A8V1AMQ2_CHICK Isoform 1 of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMKK1 PE=4 SV=1 CANONICAL=A0A8V1AMQ2-1" }, "locus": { "chromosome": "19", "start_pos": 3898311, "end_pos": 3849648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070668.1", "url": "https://www.ensembl.org/id/ENSGALT00010070668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043359.1", "url": "https://www.ensembl.org/id/ENSGALP00010043359.1" } ] } }, { "isoform_ac": "F1NKZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2/entry#F1NKZ8-1", "sequence": { "sequence": "MEDSPTDVVGEDSDTGFQDTQAELAERVAAIDVAAHPNRSDQNGEDITEENDTVFSDNVKDIQRNGVNSDVETNEFLLSQQSDNAQSGHASKKPLARPVLSSRKLSLQERSSGSHLASSNTPGFGHYATGPSPRIIRRPTIESNRVSISDAEDCVQLNQYKLQSEIGKGSYGVVKLAYNKDDDKYYAMKVLSKKKLLKQYGFPRRPPPRGSKTSTGEHSKTMAPLDRVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYMVFDLLRKGAVMEVPSDKPFSEDQARLYFRDIVLGIEYLHYQKIIHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAISDTGKSFSGKALDVWAMGITLYCFVYGKCPFIDEYILGLHNKIKSKPVEFPEESQISDELKELILRMLDKNPETRITVPEIKVHPWLTKGGEEPLPLEEEHCTVVEVTEEEVKNSVKTIPSLPAVILVKAMLRKRSFGNPFEVQTRREERSMSAPGNLLIKQGSREGGRDSELPDVCEDEATS", "length": 537, "header": "tr|F1NKZ8-1|F1NKZ8_CHICK Computationally mapped isoform of calcium/calmodulin-dependent protein kinase OS=Gallus gallus OX=9031 GN=CAMKK1 PE=4 SV=3 CANONICAL=A0A8V1AMQ2-1" }, "locus": { "chromosome": "19", "start_pos": 3893824, "end_pos": 3849648, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070667.1", "url": "https://www.ensembl.org/id/ENSGALT00010070667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043358.1", "url": "https://www.ensembl.org/id/ENSGALP00010043358.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:771003", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771003", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": 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"name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "CAMKK-AMPK signaling cascade", "id": "GO:0061762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061762", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], 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"ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + 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{ "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] 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{ "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] } ] }, { "uniprot_ac": "Q5ZJH6", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJH6" } ] } ] }, { "uniprot_ac": "Q5ZJK4", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5ZJK4", "database": "UniProtKB", "url": 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gallus OX=9031 GN=NPTX1 PE=4 SV=1 CANONICAL=A0A8V1AP67-1" }, "locus": { "chromosome": "18", "start_pos": 10109420, "end_pos": 10107528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071441.1", "url": "https://www.ensembl.org/id/ENSGALT00010071441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044131.1", "url": "https://www.ensembl.org/id/ENSGALP00010044131.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP67" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "axonogenesis involved in innervation", "id": "GO:0060385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060385", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP67", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AP67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP67" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 251, "end_pos": 453, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMQ7-1", "uniprot_ac": "A0A8V1AMQ7", "uniprot_id": "A0A8V1AMQ7_CHICK", "mass": { "chemical_mass": 233104.0, "monoisotopic_mass": 233104.0 }, "refseq": { "ac": "XP_040506051", "name": "peripheral-type benzodiazepine receptor-associated protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506051" }, "gene_names": [ { "name": "TSPOAP1", "type": "recommended", "evidence": [ { "id": "A0A8V1AMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" } ] }, { "name": "TSPOAP1", "type": "synonym", "evidence": [ { "id": "XP_040506051", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506051" } ] } ], "protein_names": [ { "name": "RIMS-binding protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7/entry#names_and_taxonomy" } ] }, { "name": "peripheral-type benzodiazepine receptor-associated protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040506051", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506051" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506051" } ] }, { "annotation": "Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AJ45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ45#function" }, { "database": "UniProtKB", "id": "ARBA00054159", "url": "https://www.uniprot.org/uniprotkb/ARBA00054159#function" }, { "database": "UniProtKB", "id": "A0A8V1AKV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV2#function" }, { "database": "UniProtKB", "id": "A0A8V1AMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSPOAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7", "locus": { "chromosome": "19", "start_pos": 968074, "end_pos": 1030483, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029572", "url": "https://www.ensembl.org/id/ENSGALG00010029572" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12013", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12013", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12014", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12014", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417469", "url": "https://www.ncbi.nlm.nih.gov/gene/417469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ45", "url": "https://www.orthodb.org/?gene=A0A8V1AJ45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKV2", "url": "https://www.orthodb.org/?gene=A0A8V1AKV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMQ7", "url": "https://www.orthodb.org/?gene=A0A8V1AMQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-181429", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-181430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-196108", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196108", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-212676", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-264642", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040506051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506051", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ45", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPEPPQTGHAVPVASASPDVALLTDTREGAGGGGDSAPRVAPGRERDDAPRPPEDSPSPDPQLVRPPRAMEGLGRERPDGPPQSGADYSFLVSQNMKLLSALEDLRHRCSSLTEENSLLRRSCFPETEEKVKHLKRKNAELAVIAKRLEERARKLQEANLKVVTAPVPLKGSSLELCKKAFARQRAKDLTEQASALLAKDKQIEALQQECRELQAKLIAGKGDPRCLNVVEFDRLLRESQKEVLRLQRQIALKNFKECLRPSKGSSGGSLPSAASCPGPALNACSKDSPAAKEVCSGGPALGGAAHGKVEPGVLPLGPALEGHENFPPKNAVADQESSQQIQQLEFELKKKRKKCENLEHEVRKKHKRCKELEIQLQEVQSENARLAEENLQLNEKAGWAGQVESENADLKLQVVLVTKERDSVIQRNQGLQTKLENLEQVLKHMRDVAERRQLLEAEHKEALLVLQEKQEEVRRLQQAQAEAKREHEGAVQLLEARVKDLEDQCRSQTEQFSLLSQELKQFRLQTGKIDLLTSTLVTSELPLALCSSTPQPHWEKDSPGPALLAHQSTKKVHNEETNESESSQRVPEAAVGSPVSTASSQKQAKKAESQSSSSKSESMQNSSKSCPTPEVDTASEMEELDVDSISLMPDPGSQGPAKLQVFLARYSYNPFDGPNENPEAELPLTAGEYIYIYGDMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLVTVLPSELNDLTHSSYQEKSFVSASTSSGDKSDFSIEESSISPLVSRAEGDQEERVSHTAVPYPRKLTLIKQLARSIVVGWEPPLMPAGCPDIQSYNIYVDEELRQNVKSGFQTKAVIEKLDLKTKAYRVSVQSVTEKGSSDKLRCTFYVGQDLCVAPTMLKVRNVTATSAEVTWLPCNSNYNHAVYLNGEECDITKPGVYWYTFCNLQPNTQYVAKLEARPLKTLWEEVSEGQEQNSAVIHFTTPLAGTPDAPLDVQVEVGPSPGILVISWLPVTIDAEGSSNGVRVTGYAVYADGQKAIEVTSPTAGSVLVDLSQLQMFQVCREVSVRTMSLYGESVDSVPAQISSVLLRASHRSSPSDSAVSTTLTSRLPCGESRGSLPARSPPTHQTAALLLRQKVPTDLSDAKLTDLSSSHDGSAQSLPEKASLLLQLSPSSASLVHTSGTSLQGSDTAQDKKCLTVPPQQAGSTKLLGEGTEPVSSREAELKSLGEGTEVLMEQNVNKMPELESPINASLMIRMETCHTCSVEESPTSPSAERETEAKEKNLSPEPLPSPSQAEEMEGTSRDASVGGSSCQEFLRLSPSKEVMKEMSRVKREQEEKMSEIGRRQLTLFTEHNRSSDLSDILEEEEEDELSSETLDEKKWDPREPCYRENGEKMDLCDTDSDEEILERILELPLQKNHSKKLFSIPEVTEDEDEDEDEKCVTEEKENPQGSLEAPTYIAGRSEKPLSTQDPFPKADGSDSSPDLSAQTPWEEQTAKGSRGGADHMSPSWSQKRTNWNWGYQENDLKSGSGTSPTRSKKKGNNYREKIRGRPEMGRKRQNDFTEHCSRLLGNCSQMGGGLYRAPSLREELNIVSSSAGKEGFDAYTRARQSASRRNHGKTMVSGFAEPAGMAAHCSSSRSLEIDIEYDSEDDQDSTCSSPPESRLWPERAQNCQGEWSDCSSQSEVFHTGGRRNLTRLERVEEQGMEWAGSPSRRLQSFCQEKEALRCESSSEEQGWEQDCKSPGWRRRLEHPWKGIRSTSLHKRASGNKDPRGQELPGSAAWQTPSRRGNRSLQRSQMQKPSLSSPGPPRSSASETTVEDDGIRIFVALFDYDPVSMSPNPDAAEEELPFKEGQILKVCGDKDADGFYRGECAGREGYIPCNMVSEVQVENNEIKMQLLKQGFLPADPPTESIGNGTFSPPPRRQTVPPPKPRRAKKAELDKQEKYKSHPGQKHQDFEAELLTPRSMVAVFDYNPKESSPNADAEAELTFSAGDIITVFGSMDDDGFYYGELNQQRGLVPSNFLEAVTSDGDVVEELHSKDKDTFLLSAESQLNPDGSVDHSDFSPTPPAPPSCLVMGEQCPEQASLAVLKCNDLPSQSKKKRGFFIKGKKLFRKLGSSKKD", "length": 2115, "header": "tr|A0A8V1AMQ7-1|A0A8V1AMQ7_CHICK Isoform 1 of RIMS-binding protein 2 OS=Gallus gallus OX=9031 GN=TSPOAP1 PE=3 SV=1 CANONICAL=A0A8V1AMQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJ45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7/entry#A0A8V1AJ45-1", "sequence": { "sequence": "MDPEPPQTGHAVPVASASPDVALLTDTREGAGGGGDSAPRVAPGRERDDAPRPPEDSPSPDPQLVRPPRAMEGLGRERPDGPPQSGADYSFLVSQNMKLLSALEDLRHRCSSLTEENSLLRRSCFPETEEKVKHLKRKNAELAVIAKRLEERARKLQEANLKVVTAPVPLKGSSLELCKKAFARQRAKDLTEQASALLAKDKQIEALQQECRELQAKLIAGKGDPRCLNVVEFDRLLRESQKEVLRLQRQIALKNFKECLRPSKGSSGGSLPSAASCPGPALNACSKDSPAAKEVCSGGPALGGAAHGKVEPGVLPLGPALEGHENFPPKNAVADQESSQQIQQLEFELKKKRKKCENLEHEVRKKHKRCKELEIQLQEVQSENARLAEENLQLNEKAGWAGQVESENADLKLQVVLVTKERDSVIQRNQGLQTKLENLEQVLKHMRDVAERRQLLEAEHKEALLVLQEKQEEVRRLQQAQAEAKREHEGAVQLLEARVKDLEDQCRSQTEQFSLLSQELKQFRLQTGKIDLLTSTLVTSELPLALCSSTPQPHWEKDSPGPALLAHQSTKKVHNEETNESESSQRVPEAAVGSPVSTASSQKQAKKAESQSSSSKSESMQNSSKSCPTPEVDTASEMEELDVDSISLMPDPGSQGPAKLQVFLARYSYNPFDGPNENPEAELPLTAGEYIYIYGDMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLVTVLPSELNDLTHSSYQEKSFVSASTSSGDKSDFSIEESSISPLVSRAEGDQEERVSHTAVPYPRKLTLIKQLARSIVVGWEPPLMPAGCPDIQSYNIYVDEELRQNVKSGFQTKAVIEKLDLKTKAYRVSVQSVTEKGSSDKLRCTFYVGQDLCVAPTMLKVRNVTATSAEVTWLPCNSNYNHAVYLNGEECDITKPGVYWYTFCNLQPNTQYVAKLEARPLKTLWEEVSEGQEQNSAVIHFTTPLAGTPDAPLDVQVEVGPSPGILVISWLPVTIDAEGSSNGVRVTGYAVYADGQKAIEVTSPTAGSVLVDLSQLQMFQVCREVSVRTMSLYGESVDSVPAQISSVLLRASHRSSPSDSAVSTTLTSRLPCGESRGSLPARSPPTHQTAALLLRQKVPTDLSDAKLTDLSSSHDGSAQSLPEKASLLLQLSPSSASLVHTSGTSLQGSDTAQDKKCLTVPPQQAGSTKLLGEGTEPVSSREAELKSLGEGTEVLMEQNVNKMPELESPINASLMIRMETCHTCSVEESPTSPSAERETEAKEKNLSPEPLPSPSQAEEMEGTSRDASVGGSSCQEFLRLSPSKEVMKEMSRVKREQEEKMSEIGRRQLTLFTEHNRSSDLSDILEEEEEDELSSETLDEKKWDPREPCYRENGEKMDLCDTDSDEEILERILELPLQKNHSKKLFSIPEVTEDEDEDEDEKCVTEEKENPQGSLEAPTYIAGRSEKPLSTQDPFPKADGSDSSPDLSAQTPWEEQTAKGSRGGADHMSPSWSQKRTNWNWGYQENDLKSGSGTSPTRSKKKGNNYREKIRGRPEMGRKRQNDFTEHCSRLLGNCSQMGGGLYRAPSLREELNIVSSSAGKEGFDAYTRARQSASRRNHGKTMVSGFAEPAGMAAHCSSSRSLEIDIEYDSEDDQDSTCSSPPESRLWPERAQNCQGEWSDCSSQSEVFHTGGRRNLTRLERVEEQGMEWAGSPSRRLQSFCQEKEALRCESSSEEQGWEQDCKSPGWRRRLEHPWKGIRSTSLHKRASGNKDPRGQELPGSAAWQTPSRRGNRSLQRSQMQKPSLSSPGPPRSSASETTVEDDGIRIFVALFDYDPVSMSPNPDAAEEELPFKEGQILKVCGDKDADGFYRGECAGREGYIPCNMVSEVQVENNEIKMQLLKQGFLPADPPTESIGNGTFSPPPRRQTVPPPKPRRAKKAELDKQEKYKSHPGQKHQDFEAELLTPRSMVAVFDYNPKESSPNADAEAELTFSAGDIITVFGSMDDDGFYYGELNQQRGLVPSNFLEAVTSDGDVVEELHSKDKDTFLLSAESQRMRKRRVQ", "length": 2053, "header": "tr|A0A8V1AJ45-1|A0A8V1AMQ7_CHICK Computationally mapped isoform of RIMS-binding protein 2 OS=Gallus gallus OX=9031 GN=TSPOAP1 PE=3 SV=1 CANONICAL=A0A8V1AMQ7-1" }, "locus": { "chromosome": "19", "start_pos": 1030284, "end_pos": 970850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071469.1", "url": "https://www.ensembl.org/id/ENSGALT00010071469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044159.1", "url": "https://www.ensembl.org/id/ENSGALP00010044159.1" } ] } }, { "isoform_ac": "A0A8V1AKV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7/entry#A0A8V1AKV2-1", "sequence": { "sequence": "MDPEPPQTGHAVPVASASPDVALLTDTREGAGGGGDSAPRVAPGRERDDAPRPPEDSPSPDPQLVRPPRAMEGLGRERPDGPPQSGADYSFLVSQNMKLLSALEDLRHRCSSLTEENSLLRRSCFPETEEKVKHLKRKNAELAVIAKRLEERARKLQEANLKVVTAPVPLKGSSLELCKKAFARQRAKDLTEQASALLAKDKQIEALQQECRELQAKLIAGKGDPRCLNVVEFDRLLRESQKEVLRLQRQIALKNFKECLRPSKGSSGGSLPSAASCPGPALNACSKDSPAAKEVCSGGPALGGAAHGKVEPGVLPLGPALEGHENFPPKNAVADQESSQQIQQLEFELKKKRKKCENLEHEVRKKHKRCKELEIQLQEVQSENARLAEENLQLNEKAGWAGQVESENADLKLQVVLVTKERDSVIQRNQGLQTKLENLEQVLKHMRDVAERRQLLEAEHKEALLVLQEKQEEVRRLQQAQAEAKREHEGAVQLLEARVKDLEDQCRSQTEQFSLLSQELKQFRLQTGKIDLLTSTLVTSELPLALCSSTPQPHWEKDSPGPALLAHQSTKKVHNEETNESESSQRVPEAAVGSPVSTASSQKQAKKAESQSSSSKSESMQNSSKSCPTPEVDTASEMEELDVDSISLMPDPGSQGPAKLQVFLARYSYNPFDGPNENPEAELPLTAGEYIYIYGDMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLVTVLPSELNDLTHSSYQEKSFVSASTSSGDKSDFSIEESSISPLVSRAEGDQEERVSHTAVPYPRKLTLIKQLARSIVVGWEPPLMPAGCPDIQSYNIYVDEELRQNVKSGFQTKAVIEKLDLKTKAYRVSVQSVTEKGSSDKLRCTFYVGQDLCVAPTMLKVRNVTATSAEVTWLPCNSNYNHAVYLNGEECDITKPGVYWYTFCNLQPNTQYVAKLEARPLKTLWEEVSEGQEQNSAVIHFTTPLAGTPDAPLDVQVEVGPSPGILVISWLPVTIDAEGSSNGVRVTGYAVYADGQKAIEVTSPTAGSVLVDLSQLQMFQVCREVSVRTMSLYGESVDSVPAQISSVLLRASHRSSPSDSAVSTTLTSRLPCGESRGSLPARSPPTHQTAALLLRQKVPTDLSDAKLTDLSSSHDGSAQSLPEKASLLLQLSPSSASLVHTSGTSLQGSDTAQDKKCLTVPPQQAGSTKLLGEGTEPVSSREAELKSLGEGTEVLMEQNVNKMPELESPINASLMIRMETCHTCSVEESPTSPSAERETEAKEKNLSPEPLPSPSQAEEMEGTSRDASVGGSSCQEFLRLSPSKEVMKEMSRVKREQEEKMSEIGRRQLTLFTEHNRSSDLSDILEEEEEDELSSETLDEKKWDPREPCYRENGEKMDLCDTDSDEEILERILELPLQKNHSKKLFSIPEVTEDEDEDEDEKCVTEEKENPQGSLEAPTYIAGRSEKPLSTQDPFPKADGSDSSPDLSAQTPWEEQTAKGSRGGADHMSPSWSQKRTNWNWGYQENDLKSGSGTSPTRSKKKGNNYREKIRGRPEMGRKRQNDFTEHCSRLLGNCSQMGGGLYRAPSLREELNIVSSSAGKEGFDAYTRARQSASRRNHGKTMVSGFAEPAGMAAHCSSSRSLEIDIEYDSEDDQDSTCSSPPESRLWPERAQNCQGEWSDCSSQSEVFHTGGRRNLTRLERVEEQGMEWAGSPSRRLQSFCQEKEALRCESSSEEQGWEQDCKSPGWRRRLEHPWKGIRSTSLHKRASGNKDPRGQELPGSAAWQTPSRRGNRSLQRSQMQKPSLSSPGPPRSSASETTVEDDGIRIFVALFDYDPVSMSPNPDAAEEELPFKEGQILKVCGDKDADGFYRGECAGREGYIPCNMVSEVQVENNEIKMQLLKQGFLPADPPTESIELDKQEKYKSHPGQKHQDFEAELLTPRSMVAVFDYNPKESSPNADAEAELTFSAGDIITVFGSMDDDGFYYGELNQQRGLVPSNFLEAVTSDGDVVEELHSKDKDTFLLSAESQLNPDGSVDHSDFSPTPPAPPSCLVMGEQCPEQASLAVLKCNDLPSQSKKKRGFFIKGKKLFRKLGSSKKD", "length": 2090, "header": "tr|A0A8V1AKV2-1|A0A8V1AMQ7_CHICK Computationally mapped isoform of RIMS-binding protein 2 OS=Gallus gallus OX=9031 GN=TSPOAP1 PE=3 SV=1 CANONICAL=A0A8V1AMQ7-1" }, "locus": { "chromosome": "19", "start_pos": 1030284, "end_pos": 969078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071471.1", "url": "https://www.ensembl.org/id/ENSGALT00010071471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044161.1", "url": "https://www.ensembl.org/id/ENSGALP00010044161.1" } ] } }, { "isoform_ac": "A0A8V1AMQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7/entry#A0A8V1AMQ7-1", "sequence": { "sequence": 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"length": 2115, "header": "tr|A0A8V1AMQ7-1|A0A8V1AMQ7_CHICK Isoform 1 of RIMS-binding protein 2 OS=Gallus gallus OX=9031 GN=TSPOAP1 PE=3 SV=1 CANONICAL=A0A8V1AMQ7-1" }, "locus": { "chromosome": "19", "start_pos": 1030284, "end_pos": 969078, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071470.1", "url": "https://www.ensembl.org/id/ENSGALT00010071470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044160.1", "url": "https://www.ensembl.org/id/ENSGALP00010044160.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2060, "start_aa": "Thr", "end_pos": 2060, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2060", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 629, "start_aa": "Thr", "end_pos": 629, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr629", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-181429", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181429", "resource": "Reactome", "description": "Serotonin Neurotransmitter Release Cycle" }, { "id": "R-GGA-181430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-181430", "resource": "Reactome", "description": "Norepinephrine Neurotransmitter Release Cycle" }, { "id": "R-GGA-196108", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196108", "resource": "Reactome", "description": "Pregnenolone biosynthesis" }, { "id": "R-GGA-212676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212676", "resource": "Reactome", "description": "Dopamine Neurotransmitter Release Cycle" }, { "id": "R-GGA-264642", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264642", "resource": "Reactome", "description": "Acetylcholine Neurotransmitter Release Cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "benzodiazepine receptor binding", "id": "GO:0030156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1275, "end_pos": 1277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1346, "end_pos": 1348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1410, "end_pos": 1412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1564, "end_pos": 1566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1686, "end_pos": 1688, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1783, "end_pos": 1785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1908, "end_pos": 1910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 893, "end_pos": 895, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 885, "end_pos": 976, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ7" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 658, "end_pos": 725, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], 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}, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21437:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21437:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ADS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ68", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP97", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQQMHNLSLLQSKKNSMPSSPNAAKRLYRNLSEKLKGSHTSFDEAYFRARSDRLSLRKTSMNFQCNEAMFEAVEQQDLDAVQILLYQYTPEELDLNTPNSEGLTPLDIAILTNNIPIARTLLHVGAKESPHFVNMESRSVHLCTLVQEAQQRVTELSAQVMNEGLGTDNTEKEKQLKAWEWRYRLYKRMKAGYEHARAPEAPTNVCLMVTSSTSLTVTFQEPLSVNSAVVTKYKVEWSCSEDFAPLVGEIIMDNLQSLRCTITGLRTGQRYYIHVSAYNMRGWGPPRRSTPAYASPSNWKDCSGREPRHRGHTEALERLLQQVRAAHQHYNCRESSKLQNTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYLSVIFFYKDNLLVTNEDQIPIVEMDDSHSSSIMQDFLWFTKLSCMWDDIRWLRQNTSVSISSSTTLQARQKMLSAAAQLQNLLGTHNLGRVFYEPIKDRHGNILIVTIREVESLYSFFNGKWMQVSKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSQQRLPPGLYLGYLKLCSSVDQIKVLVLQKLPNVLCHVKIRDNSNVSRDEWEWIQTLSGSESVESMDHTSDCPTQLFLYELQMAVKALLKQINLPLHQAKHFRLYTQEVLELGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCCYKEKFISLYCRLSAVIELDSLKTQQSLREAISDSEVAAAKQRHQQVTDYIQQVDEIWREMRWITEALQYARYKQPAAGLPIKKLVNLSEEHSQKKISSTSSHLDCLPSPPSSPEARSQRRKAVSDSQPCSDEEGCSEVFLPTDSDYDSSDALSPRELDLIYSSPHDISQQAGSGLGGSAPDVLQVHDVKPCLTLKEGLTESSAFDTNAEYCTEYMSNLTMSGITAKSIDKSSSSRQPLSFLGKKRLGKHQHYNYFSRHHRWLRVHSETQSASLSEGVYTQHLMRSSDLSQEPTSSEQLQIPVDESRSTFLPHTSSLPEDGKGKYEESRQNVHRIHMEPYKTTFLSEEGKSWAMSMQSVGHEDVHNAMQQKMGPDDPLGSAVSEVFSSTL", "length": 1079, "header": "tr|A0A8V1AMR8-1|A0A8V1AMR8_CHICK Isoform 1 of Ankyrin repeat and fibronectin type III domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFN1 PE=4 SV=1 CANONICAL=A0A8V1AMR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8/entry#A0A8V1ADS9-1", "sequence": { "sequence": "MTQQMHNLSLLQSKKNSMPSSPNAAKRLYRNLSEKLKGSHTSFDEAYFRARSDRLSLRKTSMNFQCNEAMFEAVEQQDLDAVQILLYQYTPEELDLNTPNSEGLTPLDIAILTNNIPIARTLLHVGAKESPHFVNMESRSVHLCTLVQEAQQRVTELSAQVMNEGLGTDNTEKEKQLKAWEWRYRLYKRMKAGYEHARAPEAPTNVCLMVTSSTSLTVTFQEPLSVNSAVVTKYKVEWSCSEDFAPLVGEIIMDNLQSLRCTITGLRTGQRYYIHVSAYNMRGWGPPRRSTPAYASPSNWKDCSGREPRHRGHTEALERLLQQVRAAHQHYNCRESSKLQNTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYLSVIFFYKDNLLVTNEDQIPIVEMDDSHSSSIMQDFLWFTKLSCMWDDIRWLRQNTSVSISSSTTLQARQKMLSAAAQLQNLLGTHNLGRVFYEPIKDRHGNILIVTIREVESLYSFFNGKWMQVSKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSQQRLPPGLYLGYLKLCSSVDQIKVLVLQKLPNVLCHVKIRDNSNVSRDEWEWIQTLSGSESVESMDHTSDCPTQLFLYELQMAVKALLKQINLPLHQAKHFRLYTQEVLELGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCCYKEKFISLYCRLSAVIELDSLKTQQSLREAISDSEVAAAKQRHQQVTDYIQQVDEIWREMRWITEALQYARYKQPAAGLPIKKLVNLSEEHSQKKISSTSSHLDCLPSPPSSPEARSQRRKAVSDSQPCSDEEGCSEVFLPTDSDYDSSDALSPRELDLIYSSPHDISQQAGSGLGGSAPDVLQVHDVKPCLTLKEGLTESSAFDTNAEYCTEYMSNLTMSGITAKSIDKSSSSRQPLSFLGKKRLGKHQHYNYFSRHHRWLRVHSETQSASLSEGVYTQHLMRSSDLSQEPTSSEQLQIPVDESRSTFLPHTSSLPEDGKGKSLTRFPSNYSNAEESCEMQHCYPHFIEAQKD", "length": 1044, "header": "tr|A0A8V1ADS9-1|A0A8V1ADS9_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type III domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFN1 PE=4 SV=1 CANONICAL=A0A8V1AMR8-1" }, "locus": { "chromosome": "18", "start_pos": 6799059, "end_pos": 6741698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071487.1", "url": "https://www.ensembl.org/id/ENSGALT00010071487.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044177.1", "url": "https://www.ensembl.org/id/ENSGALP00010044177.1" } ] } }, { "isoform_ac": "A0A8V1AJ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8/entry#A0A8V1AJ68-1", "sequence": { "sequence": "MTQQMHNLSLLQSKKNSMPSSPNAAKRLYRNLSEKLKGSHTSFDEAYFRARSDRLSLRKTSMNFQCNEAMFEAVEQQDLDAVQILLYQYTPEELDLNTPNSEGLTPLDIAILTNNIPIARTLLHVGAKESPHFVNMESRSVHLCTLVQEAQQRVTELSAQVMNEGLGTDNTEKEKQLKAWEWRYRLYKRMKAGYEHARAPEAPTNVCLMVTSSTSLTVTFQEPLSVNSAVVTKYKVEWSCSEDFAPLVGEIIMDNLQSLRCTITGLRTGQRYYIHVSAYNMRGWGPPRRSTPAYASPSNWKDCSGREPRHRGHTEALERLLQQVRAAHQHYNCRESSKLQNTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYLSVIFFYKDNLLVTNEDQIPIVEMDDSHSSSIMQDFLWFTKLSCMWDDIRWLRQNTSVSISSSTTLQARQKMLSAAAQLQNLLGTHNLGRVFYEPIKDRHGNILIVTIREVESLYSFFNGKWMQVSKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSQQRLPPGLYLGYLKLCSSVDQIKVLVLQKLPNVLCHVKIRDNSNVSRDEWEWIQTLSGSESVESMDHTSDCPTQLFLYELQMAVKALLKQINLPLHQAKHFRLYTQEVLELGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCCYKEKFISLYCRLSAVIELDSLKTQQSLREAISDSEVAAAKQRHQQVTDYIQQVDEIWREMRWITEALQYARYKQPAAGLPIKKLVNLSEEHSQKKISSTSSHLDCLPSPPSSPEARSQRRKAVSDSQPCSDEEGCSEVFLPTDSDYDSSDALSPRELDLIYSSPHDISQQAGSGLGGSAPDVLQVHDVKPCLTLKEGLTESSAFDTNAEYCTEYMSNLTMSGITAKSIDKSSSSRQPLSFLGKKRLGKHQHYNYFSRHHRWLRVHSETQSASLSEGVYTQHLMRSSDLSQEPTSSEQLQIPVDESRSTFLPHTSSLPEDGKGKIYQTEVTSLTQVCPAGVFLNTSTSCRRRGVVPRTGVFRYLFLSPPQP", "length": 1060, "header": "tr|A0A8V1AJ68-1|A0A8V1AMR8_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type III domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFN1 PE=4 SV=1 CANONICAL=A0A8V1AMR8-1" }, "locus": { "chromosome": "18", "start_pos": 6812788, "end_pos": 6741698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071489.1", "url": "https://www.ensembl.org/id/ENSGALT00010071489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044179.1", "url": "https://www.ensembl.org/id/ENSGALP00010044179.1" } ] } }, { "isoform_ac": "A0A8V1AMR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8/entry#A0A8V1AMR8-1", "sequence": { "sequence": "MTQQMHNLSLLQSKKNSMPSSPNAAKRLYRNLSEKLKGSHTSFDEAYFRARSDRLSLRKTSMNFQCNEAMFEAVEQQDLDAVQILLYQYTPEELDLNTPNSEGLTPLDIAILTNNIPIARTLLHVGAKESPHFVNMESRSVHLCTLVQEAQQRVTELSAQVMNEGLGTDNTEKEKQLKAWEWRYRLYKRMKAGYEHARAPEAPTNVCLMVTSSTSLTVTFQEPLSVNSAVVTKYKVEWSCSEDFAPLVGEIIMDNLQSLRCTITGLRTGQRYYIHVSAYNMRGWGPPRRSTPAYASPSNWKDCSGREPRHRGHTEALERLLQQVRAAHQHYNCRESSKLQNTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYLSVIFFYKDNLLVTNEDQIPIVEMDDSHSSSIMQDFLWFTKLSCMWDDIRWLRQNTSVSISSSTTLQARQKMLSAAAQLQNLLGTHNLGRVFYEPIKDRHGNILIVTIREVESLYSFFNGKWMQVSKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSQQRLPPGLYLGYLKLCSSVDQIKVLVLQKLPNVLCHVKIRDNSNVSRDEWEWIQTLSGSESVESMDHTSDCPTQLFLYELQMAVKALLKQINLPLHQAKHFRLYTQEVLELGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCCYKEKFISLYCRLSAVIELDSLKTQQSLREAISDSEVAAAKQRHQQVTDYIQQVDEIWREMRWITEALQYARYKQPAAGLPIKKLVNLSEEHSQKKISSTSSHLDCLPSPPSSPEARSQRRKAVSDSQPCSDEEGCSEVFLPTDSDYDSSDALSPRELDLIYSSPHDISQQAGSGLGGSAPDVLQVHDVKPCLTLKEGLTESSAFDTNAEYCTEYMSNLTMSGITAKSIDKSSSSRQPLSFLGKKRLGKHQHYNYFSRHHRWLRVHSETQSASLSEGVYTQHLMRSSDLSQEPTSSEQLQIPVDESRSTFLPHTSSLPEDGKGKYEESRQNVHRIHMEPYKTTFLSEEGKSWAMSMQSVGHEDVHNAMQQKMGPDDPLGSAVSEVFSSTL", "length": 1079, "header": "tr|A0A8V1AMR8-1|A0A8V1AMR8_CHICK Isoform 1 of Ankyrin repeat and fibronectin type III domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFN1 PE=4 SV=1 CANONICAL=A0A8V1AMR8-1" }, "locus": { "chromosome": "18", "start_pos": 6796244, "end_pos": 6741698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071485.1", "url": "https://www.ensembl.org/id/ENSGALT00010071485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044175.1", "url": "https://www.ensembl.org/id/ENSGALP00010044175.1" } ] } }, { "isoform_ac": "A0A8V1AP97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8/entry#A0A8V1AP97-1", "sequence": { "sequence": "MTQQMHNLSLLQSKKNSMPSSPNAAKRLYRNLSEKLKGSHTSFDEAYFRARSDRLSLRKTSMNFQCNEAMFEAVEQQDLDAVQILLYQYTPEELDLNTPNSEGLTPLDIAILTNNIPIARTLLHVGAKESPHFVNMESRSVHLCTLVQEAQQRVTELSAQVMNEGLGTDNTEKEKQLKAWEWRYRLYKRMKAGYEHARAPEAPTNVCLMVTSSTSLTVTFQEPLSVNSAVVTKYKVEWSCSEDFAPLVGEIIMDNLQSLRCTITGLRTGQRYYIHVSAYNMRGWGPPRRSTPAYASPSNWKDCSGREPRHRGHTEALERLLQQVRAAHQHYNCRESSKLQNTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYLSVIFFYKDNLLVTNEDQIPIVEMDDSHSSSIMQDFLWFTKLSCMWDDIRWLRQNTSVSISSSTTLQARQKMLSAAAQLQNLLGTHNLGRVFYEPIKDRHGNILIVTIREVESLYSFFNGKWMQVSKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSQQRLPPGLYLGYLKLCSSVDQIKVLVLQKLPNVLCHVKIRDNSNVSRDEWEWIQTLSGSESVESMDHTSDCPTQLFLYELQMAVKALLKQINLPLHQAKHFRLYTQEVLELGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCCYKEKFISLYCRLSAVIELDSLKTQQSLREAISDSEVAAAKQRHQQVTDYIQISFAQSTSEPLETCRGAERNRPLCFHISTVSFLLISPFSHSENLVFPQCAGAYGKSLPFTSKINIRILI", "length": 810, "header": "tr|A0A8V1AP97-1|A0A8V1AP97_CHICK Computationally mapped isoform of Ankyrin repeat and fibronectin type III domain containing 1 OS=Gallus gallus OX=9031 GN=ANKFN1 PE=4 SV=1 CANONICAL=A0A8V1AMR8-1" }, "locus": { "chromosome": "18", "start_pos": 6792459, "end_pos": 6741698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071488.1", "url": "https://www.ensembl.org/id/ENSGALT00010071488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044178.1", "url": "https://www.ensembl.org/id/ENSGALP00010044178.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A571BF63-1", "protein_name": "Ankyrin-repeat and fibronectin type III domain-containing 1", "gene_name": "Ankfn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCLEKLVAVLLKTQRTSDAYKKGPWKSQRYTVSGSRVAYKRLNCDDIWARKKSRRIPMVPGGTYSPMPESQPLEDSPKALPVLGEQSNSDNDINEPVFIWGISDKAAQRKSISAGEGSFRLQQEKQQPLVHRPGRGKGRLRLPHRLPFKDRHFTCSKIIGRRFACFAQRLSYRRKQSQCDLLNESTGHLPATCSSAASKSLSWNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDSSSEQNLKKISSTSSHIDCLPSTSPSPEMHRRKAVSESQPCSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYLSSHDIAQQALSGLSGSAPDVLQVHDMKASMGPGQDPQGPGQGPDTDHSCVEFLHSLTLTGLAPKNHAKMVAGTRPPLGFLGKRKPGKHQHYGGFSRHHRWLRMHSETQSLSLSEGVYTQHLSQACGLAEDPGEAEGPGPVVDGPRGLPLAHAASLPEERRSCLQDPRRPLQRVYVEPYSDTLAGQDPKLWTSLSPTPAGRSSLPSSTSSEMSPDPTSPVSEILSSML", "length": 1286 }, "evidence": [ { "id": "A0A8V1AMR8", "url": "https://omabrowser.org/oma/group/A0A8V1AMR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6GDF6-1", "protein_name": "Fibronectin type-III domain-containing protein", "gene_name": "Ankfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEASPNRRLPFKDRHFTCSKIIGRRFACFAQRLSYRRKQSQCDLLNESTRHLPATCSSAASKSLSRNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEALFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAHVENEGFTLDNTEKEKQLKAWEWRYRLYSRMKTGFEHARAPEVPANACLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSTSKDFSPLAGEIIMDNLQTLRCTITGLITGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDNREPRHKGQSEVLESLLQQVRALHQHCSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIAVIFFYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPVRLFFYELQMAVAALLKQINIPLHQARNFRLYTQEVLEMGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELGIVACFT", "length": 763 }, "evidence": [ { "id": "A0A8V1AMR8", "url": "https://omabrowser.org/oma/group/A0A8V1AMR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N957-1", "protein_name": "Ankyrin repeat and fibronectin type-III domain-containing protein 1", "gene_name": "ANKFN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNEKRLLFKDRHFTCSKIIGRRFACFAQRLSHRRKQSQCDLLNESTGQLPTTCSSAASNSINWNCRVKMTQQMQNLHLCQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRALHQHYSCRESTKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIAVIFYYKDNILVTNEDQVPIVEIDDSHTSSITQDFLWFTKLSCMWEDIRWLRQSIPISSSSSTVLQTRQKMLAATAQLQNLLGTHNLGRVYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLFPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENNNISREEWEWIQKLSGSESMESVDHTSDCPMQLFFYELQMAVKALLQQINIPLHQARNFRLYTQEVLEMGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDPSDEQSLKKINSTSSSHIDCLPSPPPSPEMHRRKTVSDSQPCSDEEACSEVFLPTNSDYDSSDALSPRDLDLVYLSSHDIAQQTLSGLSGSAPDVLQVHDVKTPLGPGQDPQGEGPNPDHSCAEFLHSLTLTGFTPKNHAKTVSGGRPPLGFLGKRKPGKHPHYGGFSRHHRWLRIHSETQSLSLSEGIYTQHLSQACGLAQEPKEAKRAGPALDDPRGLTLAHAASLPEERNSSLQDARPSVRRLYVEPYAAAVVAQDEKPWASLSPPSGGRITLPSPTGPDVSQEGPTASPMSEILSSML", "length": 1146 }, "evidence": [ { "id": "A0A8V1AMR8", "url": "https://omabrowser.org/oma/group/A0A8V1AMR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "establishment of mitotic spindle orientation", "id": "GO:0000132", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8" } ], "pmid": "" }, { "name": "regulation of establishment of bipolar cell polarity", "id": "GO:0061172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" }, { "start_pos": 907, "end_pos": 909, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMR8", "database": "UniProtKB", "url": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMT6-1", "uniprot_ac": "A0A8V1AMT6", "uniprot_id": "A0A8V1AMT6_CHICK", "mass": { "chemical_mass": 75405.0, "monoisotopic_mass": 75405.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM25", "type": "recommended", "evidence": [ { "id": "A0A8V1AMT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V1AMT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V1AMT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], 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"categories": [ "Protein Classification" ] }, { "id": "cd19842", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19842", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJ90", "url": "https://www.orthodb.org/?gene=A0A8V1AJ90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMT6", "url": "https://www.orthodb.org/?gene=A0A8V1AMT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APB1", "url": "https://www.orthodb.org/?gene=A0A8V1APB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AJ90", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APB1", 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"tr|A0A8V1AMT6-1|A0A8V1AMT6_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM25 PE=1 SV=1 CANONICAL=A0A8V1AMT6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJ90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6/entry#A0A8V1AJ90-1", "sequence": { "sequence": "MATLTKAQSEPNLLALEEDLTCSICLSIFDAPVTVPCGHNFCAYCLEQTWASQVRDFSCPQCRTTFPDRPQLHKNTVLCRVVEQLQGCGDGKEDDEHEEEEQEAAAPIYCDSCLQAAATQTCLTCMASFCPEHLRPHYDSPAFRHHQLCPPVRDLQQRKCPQHNKLFEFFCSQHSCCICSLCLLSHKLCHTSPLQQAKDNAESALKKRLAELHNQSERSVQAMNSVKTIQRQAAETAARKRDLLRAEFLEIKALIEEKENQTLKVFMEEEKRVCNKFDYVYKILGNKKNEIQSLRDQIEMALTEGDDVLFLKRAAALQRTSIKEAFVPVIEMDNNMIHAAYQSAINLKDVVKLAVNVSVDKRTDAKPPPGKTKPPSVPSPNKPVVKKKLAADSRTHKDKIPHPTKTTLLEETDTPPSMGAPSMGAPSAANAAKVKELISSFLKKPRAELLQYAANVTLDFNTAHSKVALSERYTKMSVSDTQLNYNHHPQRFTDCPQVLGFQCFKRGIHYWEVEMQQNNFCGIGICYGSMERQGPDSRLGRNSSSWCIEWFNSKISAWHNDVEKCLPNTKATKIGVLLHCDGGFVLFLTVEEKLNLIYKFKAQFTEAVYPAFWLFSSGTVLSLW", "length": 624, "header": "tr|A0A8V1AJ90-1|A0A8V1AMT6_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM25 PE=1 SV=1 CANONICAL=A0A8V1AMT6-1" }, "locus": { "chromosome": "18", "start_pos": 6920369, "end_pos": 6913758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071512.1", "url": "https://www.ensembl.org/id/ENSGALT00010071512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044202.1", "url": "https://www.ensembl.org/id/ENSGALP00010044202.1" } ] } }, { "isoform_ac": "A0A8V1AMT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6/entry#A0A8V1AMT6-1", "sequence": { "sequence": "MQPGADPPRPSGGGEMPRNTPESRSPSFVSSQPDGSSGRMATLTKAQSEPNLLALEEDLTCSICLSIFDAPVTVPCGHNFCAYCLEQTWASQVRDFSCPQCRTTFPDRPQLHKNTVLCRVVEQLQGCGDGKEDDEHEEEEQEAAAPIYCDSCLQAAATQTCLTCMASFCPEHLRPHYDSPAFRHHQLCPPVRDLQQRKCPQHNKLFEFFCSQHSCCICSLCLLSHKLCHTSPLQQAKDNAESALKKRLAELHNQSERSVQAMNSVKTIQRQAAETAARKRDLLRAEFLEIKALIEEKENQTLKVFMEEEKRVCNKFDYVYKILGNKKNEIQSLRDQIEMALTEGDDVLFLKRAAALQRTSIKEAFVPVIEMDNNMIHAAYQSAINLKDVVKLAVNVSVDKRTDAKPPPGKTKPPSVPSPNKPVVKKKLAADSRTHKDKIPHPTKTTLLEETDTQDKRNPVKLAPSMGAPSMGAPSAANAAKVKELISSFLKKPRAELLQYAANVTLDFNTAHSKVALSERYTKMSVSDTQLNYNHHPQRFTDCPQVLGFQCFKRGIHYWEVEMQQNNFCGIGICYGSMERQGPDSRLGRNSSSWCIEWFNSKISAWHNDVEKCLPNTKATKIGVLLHCDGGFVLFLTVEEKLNLIYKFKAQFTEAVYPAFWLFSSGTVLSLW", "length": 672, "header": "tr|A0A8V1AMT6-1|A0A8V1AMT6_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM25 PE=1 SV=1 CANONICAL=A0A8V1AMT6-1" }, "locus": { "chromosome": "18", "start_pos": 6920486, "end_pos": 6913758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071513.1", "url": "https://www.ensembl.org/id/ENSGALT00010071513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044203.1", "url": "https://www.ensembl.org/id/ENSGALP00010044203.1" } ] } }, { "isoform_ac": "A0A8V1APB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6/entry#A0A8V1APB1-1", "sequence": { "sequence": "MATLTKAQSEPNLLALEEDLTCSICLSIFDAPVTVPCGHNFCAYCLEQTWASQVRDFSCPQCRTTFPDRPQLHKNTVLCRVVEQLQGCGDGKEDDEHEEEEQEAAAPIYCDSCLQAAATQTCLTCMASFCPEHLRPHYDSPAFRHHQLCPPVRDLQQRKCPQHNKLFEFFCSQHSCCICSLCLLSHKLCHTSPLQQAKDNAESALKKRLAELHNQSERSVQAMNSVKTIQRQAAETAARKRDLLRAEFLEIKALIEEKENQTLKVFMEEEKRVCNKFDYVYKILGNKKNEIQSLRDQIEMALTEGDDVLFLKRAAALQRTSIKEAFVPVIEMDNNMIHAAYQSAINLKDVVKLAVNVSVDKRTDAKPPPGKTKPPSVPSPNKPVVKKKLAADSRTHKDKIPHPTKTTLLEETDTQDKRNPVKLDAANVTLDFNTAHSKVALSERYTKMSVSDTQLNYNHHPQRFTDCPQVLGFQCFKRGIHYWEVEMQQNNFCGIGICYGSMERQGPDSRLGRNSSSWCIEWFNSKISAWHNDVEKCLPNTKATKIGVLLHCDGGFVLFLTVEEKLNLIYKFKAQFTEAVYPAFWLFSSGTVLSLW", "length": 596, "header": "tr|A0A8V1APB1-1|A0A8V1APB1_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM25 PE=1 SV=1 CANONICAL=A0A8V1AMT6-1" }, "locus": { "chromosome": "18", "start_pos": 6920369, "end_pos": 6913758, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071511.1", "url": "https://www.ensembl.org/id/ENSGALT00010071511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044201.1", "url": "https://www.ensembl.org/id/ENSGALP00010044201.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "RIG-I binding", "id": "GO:0039552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "regulation of viral entry into host cell", "id": "GO:0046596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "suppression of viral release by host", "id": "GO:0044790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "host-mediated suppression of symbiont invasion", "id": "GO:0046597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046597", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "viral release from host cell", "id": "GO:0019076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019076", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0002753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002753", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMT6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5653756", "name": "TRIM25 binds monoUb:164-PCNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AMT6-1", "A0A8V1A4H7-1", "A0A8V0Y2U3-1" ], "evidence": [ { "id": "R-GGA-5653756", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5653756" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y2U3", "gene_name": "POLK", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V0Y2U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2U3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V0Y2U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2U3" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": 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[ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABZ4", "url": "https://www.orthodb.org/?gene=A0A8V1ABZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJC2", "url": "https://www.orthodb.org/?gene=A0A8V1AJC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALF4", "url": "https://www.orthodb.org/?gene=A0A8V1ALF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN05", "url": "https://www.orthodb.org/?gene=A0A8V1AN05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10658:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10658:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAAVRRGRNAGLHRFIGDQWHMQNILKDSVESSDDEFFDAREEVVEGKSAILIGMSQWNSNDLVEQIETIGKLEENQGEESVFCSSGFLQEKQRELYRASLRKQRLPAQGSIEVHEDNEEAVQHQKCKTRVLILILHGGNILDTGGEDQSSKLADINTFSSVFEKVTQDHFPAALGHILIRLVPCPAICSAAFSLVSNLNPYSYDESCLSSSEDHIPLAALPLLAVSSPQYQDAVAMVISRANQVYNDFLKSTDGVGFNGQVCLVGDCIGGILGFDAICYNTNRTDESQNSSRRGSISSIQDNPLLTEDSSLSGRKHLSKSNIDISEIVEDEEPRQLLPRKQSDSSTYNCDTITHHHAFLSSIHSSVLKDDADFLPVNSSLSDINLGRFDFEVSDFFLFGSPLGLVLAMRSTVLPGLDVGQVRPACSQVYSFFHSADPSACRLEPLLEKRFHLLPPFGVPRYQRYPLGDGRSHQLGDAIQNYSALFLENSSLNIIHSQESSESTNTSQKQERRLSLASTNSENSGSAESLSSACLTNITTKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYENVNFKENDSLDPVTLSPSNPREKWLRKRTHVKLRNVTANHRANDIIAAEDGPQVLVGRFMYGPLDMIALTGEKVDIFIMTEPSSGRWVYFDTEISSSSGRISYSIPKQKRLRVGVYPIKMVVRGDQSSATSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKTIFLRNLMQECHIKICAAYGSTKDISVYNVLALSPSQIYIVGRSTKKYQTQCQFLSEGYAAHLASLEFSLHSRPKKNNSRMILRKGSFGLHSQPEFLRKRNHLRRTMSVQQPDPPSSNPKPERAQSQPESDKDHDRHLPSIAWVRGGVHKFESVP", "length": 972, "header": "tr|A0A8V1AN05-1|A0A8V1AN05_CHICK Isoform 1 of Membrane-associated phosphatidylinositol transfer protein 3 OS=Gallus gallus OX=9031 GN=PITPNM3 PE=3 SV=1 CANONICAL=A0A8V1AN05-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05/entry#A0A8V1ABZ4-1", "sequence": { "sequence": "MRTMRPHHFTFHGRLLSVYACIHVLINLYMRFMAVSSSTIFTLSVNVWEAVQHQKCKTRVLILILHGGNILDTGGEDQSSKLADINTFSSVFEKVTQDHFPAALGHILIRLVPCPAICSAAFSLVSNLNPYSYDESCLSSSEDHIPLAALPLLAVSSPQYQDAVAMVISRANQVYNDFLKSTDGVGFNGQVCLVGDCIGGILGFDAICYNTNRTDESQNSSRRGSISSIQDNPLLTEDSSLSGRKHLSKSNIDISEIVEDEEPRQLLPRKQSDSSTYNCDTITHHHAFLSSIHSSVLKDDADFLPVNSSLSDINLGRFDFEVSDFFLFGSPLGLVLAMRSTVLPGLDVGQVRPACSQVYSFFHSADPSACRLEPLLEKRFHLLPPFGVPRYQRYPLGDGRSHQLGDAIQNYSALFLENSSLNIIHSQESSESTNTSQKQERRLSLASTNSENSGSAESLSSACLTNITTKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYENVNFKENDSLDPVTLSPSNPREKWLRKRTHVKLRNVTANHRANDIIAAEDGPQVLVGRFMYGPLDMIALTGEKVDIFIMTEPSSGRWVYFDTEISSSSGRISYSIPKQKRLRVGVYPIKMVVRGDQSSATSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKTIFLRNLMQECHIKICAAYGSTKDISVYNVLALSPSQIYIVGRSTKKYQTQCQFLSEGYAAHLASLEFSLHSRPKKNNSRMILRKGSFGLHSQPEFLRKRNHLRRTMSVQQPDPPSSNPKPERAQSQPESDKDHDRHLPSIAWVRGGVHKFESVP", "length": 900, "header": "tr|A0A8V1ABZ4-1|A0A8V1ABZ4_CHICK Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 3 OS=Gallus gallus OX=9031 GN=PITPNM3 PE=3 SV=1 CANONICAL=A0A8V1AN05-1" }, "locus": { "chromosome": "19", "start_pos": 10361516, "end_pos": 10335350, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070833.1", "url": "https://www.ensembl.org/id/ENSGALT00010070833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043524.1", "url": "https://www.ensembl.org/id/ENSGALP00010043524.1" } ] } }, { "isoform_ac": "A0A8V1AJC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05/entry#A0A8V1AJC2-1", "sequence": { "sequence": "MQNILKDSVESSDDEFFDAREEVVEGKSAILIGMSQWNSNDLVEQIETIGKLEENQGEESVFCSSGFLQEKQRELYRASLRKQRLPAQGSIEVHEDNEEAVQHQKCKTRVLILILHGGNILDTGGEDQSSKLADINTFSSVFEKVTQDHFPAALGHILIRLVPCPAICSAAFSLVSNLNPYSYDESCLSSSEDHIPLAALPLLAVSSPQYQDAVAMVISRANQVYNDFLKSTDGVGFNGQVCLVGDCIGGILGFDAICYNTNRTDESQNSSRRGSISSIQDNPLLTEDSSLSGRKHLSKSNIDISEIVEDEEPRQLLPRKQSDSSTYNCDTITHHHAFLSSIHSSVLKDDADFLPVNSSLSDINLGRFDFEVSDFFLFGSPLGLVLAMRSTVLPGLDVGQVRPACSQVYSFFHSADPSACRLEPLLEKRFHLLPPFGVPRYQRYPLGDGRSHQLGDAIQNYSALFLENSSLNIIHSQESSESTNTSQKQERRLSLASTNSENSGSAESLSSACLTNITTKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYENVNFKENDSLDPVTLSPSNPREKWLRKRTHVKLRNVTANHRANDIIAAEDGPQVLVGRFMYGPLDMIALTGEKVDIFIMTEPSSGRWVYFDTEISSSSGRISYSIPKQKRLRVGVYPIKMVVRGDQSSATSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKTIFLRNLMQECHIKICAAYGSTKDISVYNVLALSPSQIYIVGRSTKKYQTQCQFLSEGYAAHLASLEFSLHSRPKKNNSRMILRKGSFGLHSQPEFLRKRNHLRRTMSVQQPDPPSSNPKPERAQSQPESDKDHDRHLPSIAWVRGGVHKFESVP", "length": 950, "header": "tr|A0A8V1AJC2-1|A0A8V1AN05_CHICK Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 3 OS=Gallus gallus OX=9031 GN=PITPNM3 PE=3 SV=1 CANONICAL=A0A8V1AN05-1" }, "locus": { "chromosome": "19", "start_pos": 10361516, "end_pos": 10329330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070837.1", "url": "https://www.ensembl.org/id/ENSGALT00010070837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043528.1", "url": "https://www.ensembl.org/id/ENSGALP00010043528.1" } ] } }, { "isoform_ac": "A0A8V1ALF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05/entry#A0A8V1ALF4-1", "sequence": { "sequence": "MARALRTAGLHRFIGDQWHMQNILKDSVESSDDEFFDAREEVVEGKSAILIGMSQWNSNDLVEQIETIGKLEENQGEESVFCSSGFLQEKQRELYRASLRKQRLPAQGSIEVHEDNEEAVQHQKCKTRVLILILHGGNILDTGGEDQSSKLADINTFSSVFEKVTQDHFPAALGHILIRLVPCPAICSAAFSLVSNLNPYSYDESCLSSSEDHIPLAALPLLAVSSPQYQDAVAMVISRANQVYNDFLKSTDGVGFNGQVCLVGDCIGGILGFDAICYNTNRTDESQNSSRRGSISSIQDNPLLTEDSSLSGRKHLSKSNIDISEIVEDEEPRQLLPRKQSDSSTYNCDTITHHHAFLSSIHSSVLKDDADFLPVNSSLSDINLGRFDFEVSDFFLFGSPLGLVLAMRSTVLPGLDVGQVRPACSQVYSFFHSADPSACRLEPLLEKRFHLLPPFGVPRYQRYPLGDGRSHQLGDAIQNYSALFLENSSLNIIHSQESSESTNTSQKQERRLSLASTNSENSGSAESLSSACLTNITTKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYENVNFKENDSLDPVTLSPSNPREKWLRKRTHVKLRNVTANHRANDIIAAEDGPQVLVGRFMYGPLDMIALTGEKVDIFIMTEPSSGRWVYFDTEISSSSGRISYSIPKQKRLRVGVYPIKMVVRGDQSSATSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKTIFLRNLMQECHIKICAAYGSTKDISVYNVLALSPSQIYIVGRSTKKYQTQCQFLSEGYAAHLASLEFSLHSRPKKNNSRMILRKGSFGLHSQPEFLRKRNHLRRTMSVQQPDPPSSNPKPERAQSQPESDKDHDRHLPSIAWVRGGVHKFESVP", "length": 969, "header": "tr|A0A8V1ALF4-1|A0A8V1ALF4_CHICK Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 3 OS=Gallus gallus OX=9031 GN=PITPNM3 PE=3 SV=1 CANONICAL=A0A8V1AN05-1" }, "locus": { "chromosome": "19", "start_pos": 10361516, "end_pos": 10320870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070836.1", "url": "https://www.ensembl.org/id/ENSGALT00010070836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043527.1", "url": "https://www.ensembl.org/id/ENSGALP00010043527.1" } ] } }, { "isoform_ac": "A0A8V1AN05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05/entry#A0A8V1AN05-1", "sequence": { "sequence": "MRAAVRRGRNAGLHRFIGDQWHMQNILKDSVESSDDEFFDAREEVVEGKSAILIGMSQWNSNDLVEQIETIGKLEENQGEESVFCSSGFLQEKQRELYRASLRKQRLPAQGSIEVHEDNEEAVQHQKCKTRVLILILHGGNILDTGGEDQSSKLADINTFSSVFEKVTQDHFPAALGHILIRLVPCPAICSAAFSLVSNLNPYSYDESCLSSSEDHIPLAALPLLAVSSPQYQDAVAMVISRANQVYNDFLKSTDGVGFNGQVCLVGDCIGGILGFDAICYNTNRTDESQNSSRRGSISSIQDNPLLTEDSSLSGRKHLSKSNIDISEIVEDEEPRQLLPRKQSDSSTYNCDTITHHHAFLSSIHSSVLKDDADFLPVNSSLSDINLGRFDFEVSDFFLFGSPLGLVLAMRSTVLPGLDVGQVRPACSQVYSFFHSADPSACRLEPLLEKRFHLLPPFGVPRYQRYPLGDGRSHQLGDAIQNYSALFLENSSLNIIHSQESSESTNTSQKQERRLSLASTNSENSGSAESLSSACLTNITTKWWGTKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYENVNFKENDSLDPVTLSPSNPREKWLRKRTHVKLRNVTANHRANDIIAAEDGPQVLVGRFMYGPLDMIALTGEKVDIFIMTEPSSGRWVYFDTEISSSSGRISYSIPKQKRLRVGVYPIKMVVRGDQSSATSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKTIFLRNLMQECHIKICAAYGSTKDISVYNVLALSPSQIYIVGRSTKKYQTQCQFLSEGYAAHLASLEFSLHSRPKKNNSRMILRKGSFGLHSQPEFLRKRNHLRRTMSVQQPDPPSSNPKPERAQSQPESDKDHDRHLPSIAWVRGGVHKFESVP", "length": 972, "header": "tr|A0A8V1AN05-1|A0A8V1AN05_CHICK Isoform 1 of Membrane-associated phosphatidylinositol transfer protein 3 OS=Gallus gallus OX=9031 GN=PITPNM3 PE=3 SV=1 CANONICAL=A0A8V1AN05-1" }, "locus": { "chromosome": "19", "start_pos": 10361516, "end_pos": 10321207, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070834.1", "url": "https://www.ensembl.org/id/ENSGALT00010070834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043525.1", "url": "https://www.ensembl.org/id/ENSGALP00010043525.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1483226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483226", "resource": "Reactome", "description": "Synthesis of PI" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" }, { "name": "phospholipid transporter activity", "id": "GO:0005548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" }, { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN05", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AN05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN05" }, { "id": "PS51043", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51043" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DDHD", "eco_id": "ECO_0000259", "start_pos": 390, "end_pos": 591, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 894, "end_pos": 896 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1APE3-1", "uniprot_ac": "A0A8V1APE3", "uniprot_id": "A0A8V1APE3_CHICK", "mass": { "chemical_mass": 59196.0, "monoisotopic_mass": 59196.0 }, "refseq": {}, "gene_names": [ { "name": "HSF5", "type": "recommended", "evidence": [ { "id": "A0A8V1APE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ] } ], "protein_names": [ { "name": "Heat shock factor protein 5", "type": "recommended", "evidence": [ { "id": "A0A8V1APE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3/entry#names_and_taxonomy" } ] }, { "name": "Heat shock transcription factor 5", "type": "synonym", "evidence": [ { "id": "A0A8V1APE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "DNA-binding transcription factor that is essential for male fertility, spermatogenesis and meiotic prophase progression in spermatocytes under non-stress conditions. Positvely and negatively regulates gene expression to ensure progression of meiotic prophase beyond pachytene stage in spermatocytes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3#function" }, { "database": "UniProtKB", "id": "ARBA00094520", "url": "https://www.uniprot.org/uniprotkb/ARBA00094520#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3", "locus": { "chromosome": "19", "start_pos": 1106914, "end_pos": 1134619, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029601", "url": "https://www.ensembl.org/id/ENSGALG00010029601" } ] } } ], "crossref": [ { "id": "A0A8V1APE3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1APE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJD5", "url": "https://www.orthodb.org/?gene=A0A8V1AJD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL43", "url": "https://www.orthodb.org/?gene=A0A8V1AL43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMX0", "url": "https://www.orthodb.org/?gene=A0A8V1AMX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APE3", "url": "https://www.orthodb.org/?gene=A0A8V1APE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AJD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEPLLPAAINPNNFPAKLWRLVNSPRFRSIRWDARGEGLLIDQPLFEAELLGRAGPRSGGDGAAGELFKTTNFTSFIRQLNLYGFRKVVAGPAGPRAGSGPESDGGSGGHLHHFHSPHFRRDRPDLLVHLKRMTSANKAKLAAGLEVSSRPPNRFQRPILTSYKNNSSKNQNPLGVSDGLLAVGQFHRPYQRDSLFPYSYISASPQNHSSLPSKSLDRTPIPSRTWQSSLGVVPGHKASTAFPDKGIAFPIFQRLPTEVTYTLQSSASPVPLQQVSQAIATSPAKYSSYASPLHYSQAYYPTAALPCCSPATHISPLTCCASPTALTYTHCSFFQSPPVQSPYAVEFLPSTWPYHTSDESKKTEVNLEAVFQIVDEMRSSPKVGTVKVEPVENQWSSPQFNRGQPLLADTENDDPPSDEEGRLEPLTPVVSDVTSFVVGDQEVACSLSQPSEYFYALHTTASVECAAAQIVREPVATQEARGKLREEPDHLPAQFSAMIVREVQSLSPQKVSDEDKTLPLIQWYFQSLGSWQVQNSPK", "length": 539, "header": "tr|A0A8V1APE3-1|A0A8V1APE3_CHICK Isoform 1 of Heat shock factor protein 5 OS=Gallus gallus OX=9031 GN=HSF5 PE=3 SV=1 CANONICAL=A0A8V1APE3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3/entry#A0A8V1AJD5-1", "sequence": { "sequence": "MEEPLLPAAINPNNFPAKLWRLVNSPRFRSIRWDARDKGIAFPIFQRLPTEVTYTLQSSASPVPLQQVSQAIATSPAKYSSYASPLHYSQAYYPTAALPCCSPATHISPLTCCASPTALTYTHCSFFQSPPVQSPYAVEFLPSTWPYHTSDESKKTEVNLEAVFQIVDEMRSSPKVGTVKVEPVENQWSSPQFNRGQPLLADTENDDPPSDEEGRLEPLTPVVSDVTSFVVGDQEVACSLSQPSEYFYALHTTASVECAAAQIVREPVATQEARGKLREEPDHLPAQFSAMIVREVQSLSPQKVSDEDKTLPLIQWYFQSLGSWQVQNSPK", "length": 331, "header": "tr|A0A8V1AJD5-1|A0A8V1APE3_CHICK Computationally mapped isoform of Heat shock factor protein 5 OS=Gallus gallus OX=9031 GN=HSF5 PE=3 SV=1 CANONICAL=A0A8V1APE3-1" }, "locus": { "chromosome": "19", "start_pos": 1133648, "end_pos": 1115638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071558.1", "url": "https://www.ensembl.org/id/ENSGALT00010071558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044248.1", "url": "https://www.ensembl.org/id/ENSGALP00010044248.1" } ] } }, { "isoform_ac": "A0A8V1AL43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3/entry#A0A8V1AL43-1", "sequence": { "sequence": "MTSANKAKLAAGLEVSSRPPNRFQRPPGEPPPSPPTPGKADRPGLLAVGQFHRPYQRDSLFPYSYISASPQNHSSLPSKSLDRTPIPSRTWQSSLGVVPGHKASTAFPDKGIAFPIFQRLPTEVTYTLQSSASPVPLQQVSQAIATSPAKYSSYASPLHYSQAYYPTAALPCCSPATHISPLTCCASPTALTYTHCSFFQSPPVQSPYAVEFLPSTWPYHTSDESKKTEVNLEAVFQIVDEMRSSPKVGTVKVEPVENQWSSPQFNRGQPLLADTENDDPPSDEEGRLEPLTPVVSDVTSFVVGDQEVACSLSQPSEYFYALHTTASVECAAAQIVREPVATQEARGKLREEPDHLPAQFSAMIVREVQSLSPQKVDTSVKCPLLRSETEEVGCLTSGTGTVKKSIENAVSSVKTRNREKKNSSQECKSPDLHLLVDVACKQEHFPKEEIRE", "length": 452, "header": "tr|A0A8V1AL43-1|A0A8V1AL43_CHICK Computationally mapped isoform of Heat shock transcription factor 5 OS=Gallus gallus OX=9031 GN=HSF5 PE=4 SV=1 CANONICAL=A0A8V1APE3-1" }, "locus": { "chromosome": "19", "start_pos": 1133249, "end_pos": 1108497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071560.1", "url": "https://www.ensembl.org/id/ENSGALT00010071560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044250.1", "url": "https://www.ensembl.org/id/ENSGALP00010044250.1" } ] } }, { "isoform_ac": "A0A8V1AMX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3/entry#A0A8V1AMX0-1", "sequence": { "sequence": "MPLFHGPGLSSDGGSGGHLHHFHSPHFRRDRPDLLVHLKRMTSANKAKLAAGLEVSSRPPNRFQRPILTSYKNNSSKNQNPLGVSDGLLAVGQFHRPYQRDSLFPYSYISASPQNHSSLPSKSLDRTPIPSRTWQSSLGVVPGHKASTAFPDKGIAFPIFQRLPTEVTYTLQSSASPVPLQQVSQAIATSPAKYSSYASPLHYSQAYYPTAALPCCSPATHISPLTCCASPTALTYTHCSFFQSPPVQSPYAVEFLPSTWPYHTSDESKKTEVNLEAVFQIVDEMRSSPKVGTVKVEPVENQWSSPQFNRGQPLLADTENDDPPSDEEGRLEPLTPVVSDVTSFVVGDQEVACSLSQPSEYFYALHTTASVECAAAQIVREPVATQEARGKLREEPDHLPAQFSAMIVREVQSLSPQKVKEIGHYRPFAALTCPHSCLSSSGISRAWDHGRCRTLQSRFLCLYIH", "length": 465, "header": "tr|A0A8V1AMX0-1|A0A8V1AMX0_CHICK Computationally mapped isoform of Heat shock transcription factor 5 OS=Gallus gallus OX=9031 GN=HSF5 PE=4 SV=1 CANONICAL=A0A8V1APE3-1" }, "locus": { "chromosome": "19", "start_pos": 1134619, "end_pos": 1115613, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071559.1", "url": "https://www.ensembl.org/id/ENSGALT00010071559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044249.1", "url": "https://www.ensembl.org/id/ENSGALP00010044249.1" } ] } }, { "isoform_ac": "A0A8V1APE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3/entry#A0A8V1APE3-1", "sequence": { "sequence": "MEEPLLPAAINPNNFPAKLWRLVNSPRFRSIRWDARGEGLLIDQPLFEAELLGRAGPRSGGDGAAGELFKTTNFTSFIRQLNLYGFRKVVAGPAGPRAGSGPESDGGSGGHLHHFHSPHFRRDRPDLLVHLKRMTSANKAKLAAGLEVSSRPPNRFQRPILTSYKNNSSKNQNPLGVSDGLLAVGQFHRPYQRDSLFPYSYISASPQNHSSLPSKSLDRTPIPSRTWQSSLGVVPGHKASTAFPDKGIAFPIFQRLPTEVTYTLQSSASPVPLQQVSQAIATSPAKYSSYASPLHYSQAYYPTAALPCCSPATHISPLTCCASPTALTYTHCSFFQSPPVQSPYAVEFLPSTWPYHTSDESKKTEVNLEAVFQIVDEMRSSPKVGTVKVEPVENQWSSPQFNRGQPLLADTENDDPPSDEEGRLEPLTPVVSDVTSFVVGDQEVACSLSQPSEYFYALHTTASVECAAAQIVREPVATQEARGKLREEPDHLPAQFSAMIVREVQSLSPQKVSDEDKTLPLIQWYFQSLGSWQVQNSPK", "length": 539, "header": "tr|A0A8V1APE3-1|A0A8V1APE3_CHICK Isoform 1 of Heat shock factor protein 5 OS=Gallus gallus OX=9031 GN=HSF5 PE=3 SV=1 CANONICAL=A0A8V1APE3-1" }, "locus": { "chromosome": "19", "start_pos": 1133648, "end_pos": 1115638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071557.1", "url": "https://www.ensembl.org/id/ENSGALT00010071557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044247.1", "url": "https://www.ensembl.org/id/ENSGALP00010044247.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" }, { "name": "male meiotic nuclear division", "id": "GO:0007140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity", "id": "GO:0001216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity", "id": "GO:0001217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APE3" }, { "id": "SM00415", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00415" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSF-type DNA-binding", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 134, "start_aa": "Asn", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 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"protein_names": [ { "name": "Chromosome 17 open reading frame 75", "type": "synonym", "evidence": [ { "id": "A0A8V1AMY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C17orf75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3", "locus": { "chromosome": "18", "start_pos": 7358899, "end_pos": 7365494, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029605", "url": "https://www.ensembl.org/id/ENSGALG00010029605" } ] } } ], "crossref": [ { "id": "A0A8V1AMY3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMY3", "database": "AlphaFoldDB", "categories": [] }, { "id": "417412", "url": "https://www.ncbi.nlm.nih.gov/gene/417412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJF5", "url": "https://www.orthodb.org/?gene=A0A8V1AJF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL65", "url": "https://www.orthodb.org/?gene=A0A8V1AL65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMY3", "url": "https://www.orthodb.org/?gene=A0A8V1AMY3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14416:SF2", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V1AMY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSCSCAGVGMLAALPDGDEREMESSEEGGGGAGDERRPERHGSTYHSLYGYRSRRSSRRGADGGDCGAAPGSPPGRDFSLSLLDTNLPGEAETELRSFIAKRLAKGAVFEGMGNVATVDLSIPECKVGCYYCLFQQESLPETATLESETNVPEYVVCFLGGSEKGLELFRLELDKYIQSLKLSLDLEQKTLETSVNPYLRSWFENSICPIQRVVQLFQEKLAFLLHAALSYTPVEVKNADERTEKDINRFLAAASLQGLVQEGTMTSLCIAMTEEQHKSMVVDCIGAQPQLHNAGSNRFCEDWMHAFVNGAEVGNPFLFRQILENFKLKAIQDINNLKRFIRQAEMNHYALFKCYMFLKNCGSGDILLKIVKVEHAEMPEARNVVTVLEEFMRETAVA", "length": 400, "header": "tr|A0A8V1AMY3-1|A0A8V1AMY3_CHICK Isoform 1 of Chromosome 17 open reading frame 75 OS=Gallus gallus OX=9031 GN=C17orf75 PE=1 SV=1 CANONICAL=A0A8V1AMY3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3/entry#A0A8V1AJF5-1", "sequence": { "sequence": "MSGRWRAARRAAVVRETSGGRSGTAAPTTASTATGAAGPRGGVRMAAIAARRLGALPAGTSGEAETELRSFIAKRLAKGAVFEGMGNVATVDLSIPECKVGCYYCLFQQESLPETATLESETNVPEYVVCFLGGSEKGLELFRLELDKYIQSLKLSLDLEQKTLETSVNPYLRSWFENSICPIQRVVQLFQEKLAFLLHAALSYTPVEVKNADERTEKDINRFLAAASLQGLVQEGTMTSLCIAMTEEQHKSMVVDCIGAQPQLHNAGSNRFCEDWMHAFVNGAEVGNPFLFRQILENFKLKAIQDINNLKRFIRQAEMNHYALFKCYMFLKNCGSGDILLKIVKVEHAEMPEARNVVTVLEEFMRETAVA", "length": 371, "header": "tr|A0A8V1AJF5-1|A0A8V1AMY3_CHICK Computationally mapped isoform of Chromosome 17 open reading frame 75 OS=Gallus gallus OX=9031 GN=C17orf75 PE=1 SV=1 CANONICAL=A0A8V1AMY3-1" }, "locus": { "chromosome": "18", "start_pos": 7365130, "end_pos": 7361443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071578.1", "url": "https://www.ensembl.org/id/ENSGALT00010071578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044268.1", "url": "https://www.ensembl.org/id/ENSGALP00010044268.1" } ] } }, { "isoform_ac": "A0A8V1AL65-1", "url": 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"https://www.ensembl.org/id/ENSGALP00010044270.1" } ] } }, { "isoform_ac": "A0A8V1AMY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3/entry#A0A8V1AMY3-1", "sequence": { "sequence": "MSSSCSCAGVGMLAALPDGDEREMESSEEGGGGAGDERRPERHGSTYHSLYGYRSRRSSRRGADGGDCGAAPGSPPGRDFSLSLLDTNLPGEAETELRSFIAKRLAKGAVFEGMGNVATVDLSIPECKVGCYYCLFQQESLPETATLESETNVPEYVVCFLGGSEKGLELFRLELDKYIQSLKLSLDLEQKTLETSVNPYLRSWFENSICPIQRVVQLFQEKLAFLLHAALSYTPVEVKNADERTEKDINRFLAAASLQGLVQEGTMTSLCIAMTEEQHKSMVVDCIGAQPQLHNAGSNRFCEDWMHAFVNGAEVGNPFLFRQILENFKLKAIQDINNLKRFIRQAEMNHYALFKCYMFLKNCGSGDILLKIVKVEHAEMPEARNVVTVLEEFMRETAVA", "length": 400, "header": "tr|A0A8V1AMY3-1|A0A8V1AMY3_CHICK Isoform 1 of Chromosome 17 open reading frame 75 OS=Gallus gallus OX=9031 GN=C17orf75 PE=1 SV=1 CANONICAL=A0A8V1AMY3-1" }, "locus": { "chromosome": "18", "start_pos": 7365427, "end_pos": 7361443, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071579.1", "url": "https://www.ensembl.org/id/ENSGALT00010071579.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044269.1", "url": "https://www.ensembl.org/id/ENSGALP00010044269.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1API2-1", "uniprot_ac": "A0A8V1API2", "uniprot_id": "A0A8V1API2_CHICK", "mass": { "chemical_mass": 125360.0, "monoisotopic_mass": 125360.0 }, "refseq": { "ac": "XP_015135389", "name": "testis-expressed protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135389" }, "gene_names": [ { "name": "TEX2", "type": "recommended", "evidence": [ { "id": "A0A8V1API2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2" } ] }, { "name": "TEX2", "type": "synonym", "evidence": [ { "id": "XP_015135389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135389" } ] } ], "protein_names": [ { "name": "Testis expressed 2", "type": "synonym", "evidence": [ { "id": "A0A8V1API2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#names_and_taxonomy" } ] }, { "name": "testis-expressed protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015135389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135389" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135389.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135389", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135389" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TEX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2", "locus": { "chromosome": "18", "start_pos": 7424019, "end_pos": 7462086, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029618", "url": "https://www.ensembl.org/id/ENSGALG00010029618" } ] } } ], "crossref": [ { "id": "A0A8V1API2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1API2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21675", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21675", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417415", "url": "https://www.ncbi.nlm.nih.gov/gene/417415", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417415", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417415", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AE60", "url": "https://www.orthodb.org/?gene=A0A8V1AE60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE65", "url": "https://www.orthodb.org/?gene=A0A8V1AE65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJI7", "url": "https://www.orthodb.org/?gene=A0A8V1AJI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJJ1", "url": "https://www.orthodb.org/?gene=A0A8V1AJJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJJ6", "url": "https://www.orthodb.org/?gene=A0A8V1AJJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL93", "url": "https://www.orthodb.org/?gene=A0A8V1AL93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL96", "url": "https://www.orthodb.org/?gene=A0A8V1AL96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALA0", "url": "https://www.orthodb.org/?gene=A0A8V1ALA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APH6", "url": "https://www.orthodb.org/?gene=A0A8V1APH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1API2", "url": "https://www.orthodb.org/?gene=A0A8V1API2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13466:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13466:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015135389", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135389", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AE60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL93", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL96", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1API2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1API2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1119, "header": "tr|A0A8V1API2-1|A0A8V1API2_CHICK Isoform 1 of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1AE60-1", "sequence": { "sequence": "MQDSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1130, "header": "tr|A0A8V1AE60-1|A0A8V1AE60_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7454071, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071611.1", "url": "https://www.ensembl.org/id/ENSGALT00010071611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044301.1", "url": "https://www.ensembl.org/id/ENSGALP00010044301.1" } ] } }, { "isoform_ac": "A0A8V1AE65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1AE65-1", "sequence": { "sequence": "MPNTARKTRGLRGCKKRLDSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1146, "header": "tr|A0A8V1AE65-1|A0A8V1AE65_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7454524, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071616.1", "url": "https://www.ensembl.org/id/ENSGALT00010071616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044306.1", "url": "https://www.ensembl.org/id/ENSGALP00010044306.1" } ] } }, { "isoform_ac": "A0A8V1AJI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1AJI7-1", "sequence": { "sequence": "MDSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1129, "header": "tr|A0A8V1AJI7-1|A0A8V1API2_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7451643, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071608.1", "url": "https://www.ensembl.org/id/ENSGALT00010071608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044298.1", "url": "https://www.ensembl.org/id/ENSGALP00010044298.1" } ] } }, { "isoform_ac": "A0A8V1AJJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1AJJ1-1", "sequence": { "sequence": "MERSLSHCVLVNASCWVCHLGSWRQLPLFPCRDVGRTAPCAADSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1170, "header": "tr|A0A8V1AJJ1-1|A0A8V1API2_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7454105, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071613.1", "url": "https://www.ensembl.org/id/ENSGALT00010071613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044303.1", "url": "https://www.ensembl.org/id/ENSGALP00010044303.1" } ] } }, { "isoform_ac": "A0A8V1AJJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1AJJ6-1", "sequence": { "sequence": "MCGGAVCTRAVPGAALVLRRRFANSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1151, "header": "tr|A0A8V1AJJ6-1|A0A8V1API2_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7460341, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071618.1", "url": "https://www.ensembl.org/id/ENSGALT00010071618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044308.1", "url": "https://www.ensembl.org/id/ENSGALP00010044308.1" } ] } }, { "isoform_ac": "A0A8V1AL93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1AL93-1", "sequence": { "sequence": "MCEEVNSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1133, "header": "tr|A0A8V1AL93-1|A0A8V1AL93_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7453813, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071610.1", "url": "https://www.ensembl.org/id/ENSGALT00010071610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044300.1", "url": "https://www.ensembl.org/id/ENSGALP00010044300.1" } ] } }, { "isoform_ac": "A0A8V1AL96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1AL96-1", "sequence": { "sequence": "MPNTARKTRGLRGSLHDSSVLCLFLSKWIQQADSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1160, "header": "tr|A0A8V1AL96-1|A0A8V1AL96_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7454524, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071615.1", "url": "https://www.ensembl.org/id/ENSGALT00010071615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044305.1", "url": "https://www.ensembl.org/id/ENSGALP00010044305.1" } ] } }, { "isoform_ac": "A0A8V1ALA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1ALA0-1", "sequence": { "sequence": "MPNTARKTRGLRGYSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1141, "header": "tr|A0A8V1ALA0-1|A0A8V1ALA0_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7454524, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071620.1", "url": "https://www.ensembl.org/id/ENSGALT00010071620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044310.1", "url": "https://www.ensembl.org/id/ENSGALP00010044310.1" } ] } }, { "isoform_ac": "A0A8V1APH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1APH6-1", "sequence": { "sequence": "MCPVRAGDSDASLGPAMTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1135, "header": "tr|A0A8V1APH6-1|A0A8V1APH6_CHICK Computationally mapped isoform of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7446607, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071607.1", "url": "https://www.ensembl.org/id/ENSGALT00010071607.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044297.1", "url": "https://www.ensembl.org/id/ENSGALP00010044297.1" } ] } }, { "isoform_ac": "A0A8V1API2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2/entry#A0A8V1API2-1", "sequence": { "sequence": "MTSQNSSHAEKTGEMSSKQSAPKVQVQRSVSRETITIHFSAFGKEEEEEEEEFKEFLDEELDDQSIVTALEAKEDLCFEHTGHDFSGPATSLNMANSASLLSSSPAVLPAADAVKLLDSSTSQVLSAVPLVLSPSSHSCHMFSLSGASPPVEQKANFLSSPSSSPSRSVVCSSASSTVSSSKPFKGLVKSLSTDVEPKEPTPPMRHRQLMKTLVKSLSTDTSKQEPEAVSYRPPDSKLNLHLFKQFTQPRATGGDSKTAPSSPLISPSDTRSFFKVPEMEAKIEDTKRRLSEVIYEPFQLLSKIMGDESSSHRPKALSSSASELSNLSSLNGHLESNNNYSIKEEECDSEGDLYGSDSNVSKNDQSKTAEEHAKETETRSSQSASTKDVSSKTSLVLEKCSLSALASREDEEFCELYSEDFSLIEDESKTDKRPETLLDLEMTDENGIVLSSEEENNLYVQQPKIPVKTLYFLTLLVYAYFIIPLPGYLSGLLFGMALGFMTAVCVIWLLTPRTHEYLKFRESMKKQWNTGALDIKEPEILKGWMNEIYNYDPETYHATLTHSVYVRLEGSTLRLSKPNKNISRRAVYNEPKPEVTYVSQKIYELTESKISLVPKSLARKRIWNKKYPICIELARQDDFMAKAQTDKENAEEKLSSEKVDLNNEESKKAQDGAKYTSQKDQVLYLFGRTGREKEEWFRRFLLASKLKSEAKKPSSKPGILPAHGRTESQSGVPTHSRSSSKGSVEEIASQPKHKDLAGNLRQKMLLDYNIYMAKCVPQEKKSPSGSPVLSADSSPTAVKKLPDAHVEAEEEEQEVWVNALLGRIFWDFLGEKYWSDLVSKKIQMKLSKIKLPYFMNELTLTELDMGIAVPKILQAFKPSVDYRGLWIDLEMSYNGSFLMTLETKMNLTKLGKEPLGEALKVGEIGKEGFRPRAYCLADSDEESSSAGSSEEDDAPELAGEKQVTPGAEGYVGGHRTSKIMRIVDKITKSKYFQKATETEFIKKKIEEVSNTPLLLTVEVQECRGTLVINIPPPPTDRIWYGFRRPPYLELKARPKLGEREVTLVHVTEWIERKLEQEFQKIFVMPNMDDVYIPLMHSAMDPRSSTYPPKDLVTEAPDQP", "length": 1119, "header": "tr|A0A8V1API2-1|A0A8V1API2_CHICK Isoform 1 of Testis expressed 2 OS=Gallus gallus OX=9031 GN=TEX2 PE=4 SV=1 CANONICAL=A0A8V1API2-1" }, "locus": { "chromosome": "18", "start_pos": 7446021, "end_pos": 7425499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071617.1", "url": "https://www.ensembl.org/id/ENSGALT00010071617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044307.1", "url": "https://www.ensembl.org/id/ENSGALP00010044307.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417415", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417415", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1API2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API2" }, { "id": "PS51847", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SMP-LTD", "eco_id": "ECO_0000259", "start_pos": 809, "end_pos": 1093, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 201 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 326, "end_pos": 328 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 894, "end_pos": 896 }, { "start_pos": 906, "end_pos": 908 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AN16-1", "uniprot_ac": "A0A8V1AN16", "uniprot_id": "A0A8V1AN16_CHICK", "mass": { "chemical_mass": 82827.0, "monoisotopic_mass": 82827.0 }, "refseq": {}, "gene_names": [ { "name": "PECAM1", "type": "recommended", "evidence": [ { "id": "A0A8V1AN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ] } ], "protein_names": [ { "name": "Platelet endothelial cell adhesion molecule", "type": "recommended", "evidence": [ { "id": "A0A8V1AN16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PECAM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16", "locus": { "chromosome": "18", "start_pos": 7472374, "end_pos": 7501077, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029625", "url": "https://www.ensembl.org/id/ENSGALG00010029625" } ] } } ], "crossref": [ { "id": "A0A8V1AN16", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AN16", "database": "AlphaFoldDB", "categories": [] }, { "id": "771243", "url": "https://www.ncbi.nlm.nih.gov/gene/771243", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE79", "url": "https://www.orthodb.org/?gene=A0A8V1AE79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE85", "url": "https://www.orthodb.org/?gene=A0A8V1AE85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJK9", "url": "https://www.orthodb.org/?gene=A0A8V1AJK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALA8", "url": "https://www.orthodb.org/?gene=A0A8V1ALA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN16", "url": "https://www.orthodb.org/?gene=A0A8V1AN16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN19", "url": "https://www.orthodb.org/?gene=A0A8V1AN19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APJ0", "url": "https://www.orthodb.org/?gene=A0A8V1APJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APJ3", "url": "https://www.orthodb.org/?gene=A0A8V1APJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11481:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11481:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-210990", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-210990", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-216083", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-432142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AE79", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN19", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYLALLVIFLQCSEICTQKRVFTFNAVHIEVQPSAKVENGAPMSIICHADISKSTDFNLQHNITIFKDGKLVFMSVSGKGDARYEVPMARSSHTGDYQCAVEAGGKIKHSDSLHVWVTGMTKPILIAEKKEVFEGEVVKLRCELPEEVPPLYFVFQKMKVNSTPKQKLQEELYRNFSVVEFPVDEGDDILQFDCFGKRRVRFEFETSLTSNKTLITVKEPFIKPTLHIKPSSNITEGKEIRFECSTVVAKMRDIEIILLRNKTILSSVRDQTTLKYSAVATLEDSGEYLCKVEEGKASKTTTHNVVVTELFPKPILTASMNELDEHKELTLSCSIKDFQNASFSILRKHSSRDILLRNSRNLTMRASVNDTGSYICKAEVNRIVKESKPVTIRVYAPVSMPSISVFSGLPEVVLGRPLNLTCCLMMGTPPITFTFYKGNKNKKKIVTNNTCAAFLDKDIRQNDKGQYKCGAKNHHSSGMKTSKVLNITVIVPIRNTSLGSVPYGVVEDGRETTFLCSVEEGSWPIHFRIFRKMDRDILLFERSEHADRVVWQKKEMSRQDTGTYYCIASNRANVSAKSHPITINVILASWQKGVITAFVLIPIAGVMILAVWWFWCKKKNAKGPSMEMSRSALATNSTSEKLSRQHNDGDYYSGSGYIEDGENHMKSTDENKGPDLESAEVEYTEVEVSTLDPHRAPVQKGTETVYSEIRKANNGKVFEIDKQCITWLCSSFVAVC", "length": 736, "header": "tr|A0A8V1AN16-1|A0A8V1AN16_CHICK Isoform 1 of Platelet endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=PECAM1 PE=1 SV=1 CANONICAL=A0A8V1AN16-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16/entry#A0A8V1AE79-1", "sequence": { "sequence": "MYLALLVIFLQCSEICTQKRVFTFNAVHIEVQPSAKVENGAPMSIICHADISKSTDFNLQHNITIFKDGKLVFMSVSGKGDARYEVPMARSSHTGDYQCAVEAGGKIKHSDSLHVWVTGMTKPILIAEKKEVFEGEVVKLRCELPEEVPPLYFVFQKMKVNSTPKQKLQEELYRNFSVVEFPVDEGDDILQFDCFGKRRVRFEFETSLTSNKTLITVKEPFIKPTLHIKPSSNITEGKEIRFECSTVVAKMRDIEIILLRNKTILSSVRDQTTLKYSAVATLEDSGEYLCKVEEGKASKTTTHNVVVTELFPKPILTASMNELDEHKELTLSCSIKDFQNASFSILRKHSSRDILLRNSRNLTMRASVNDTGSYICKAEVNRIVKESKPVTIRVYAPVSMPSISVFSGLPEVVLGRPLNLTCCLMMGTPPITFTFYKGNKNKKKIVTNNTCAAFLDKDIRQNDKGQYKCGAKNHHSSGMKTSKVLNITVIVPIRNTSLGSVPYGVVEDGRETTFLCSVEEGSWPIHFRIFRKMDRDILLFERSEHADRVVWQKKEMSRQDTGTYYCIASNRANVSAKSHPITINVILASWQKGVITAFVLIPIAGVMILAVWWFWCKKKNAKGPSMEMSRSALATNSTSEKLSRQHNDGDYYSGSGYIEDGENHMKSTDENKGPDLESAEVEYTEVEVSTLDPHRENTGAS", "length": 701, "header": "tr|A0A8V1AE79-1|A0A8V1AE79_CHICK Computationally mapped isoform of Platelet endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=PECAM1 PE=1 SV=1 CANONICAL=A0A8V1AN16-1" }, "locus": { "chromosome": "18", "start_pos": 7500863, "end_pos": 7473866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071631.1", "url": "https://www.ensembl.org/id/ENSGALT00010071631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044321.1", "url": "https://www.ensembl.org/id/ENSGALP00010044321.1" } ] } }, { "isoform_ac": "A0A8V1AE85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16/entry#A0A8V1AE85-1", "sequence": { "sequence": "MYLALLVIFLQCSEICTQKRVFTFNAVHIEVQPSAKVENGAPMSIICHADISKSTDFNLQHNITIFKDGKLVFMSVSGKGDARYEVPMARSSHTGDYQCAVEAGGKIKHSDSLHVWVTGMTKPILIAEKKEVFEGEVVKLRCELPEEVPPLYFVFQKMKVNSTPKQKLQEELYRNFSVVEFPVDEGDDILQFDCFGKRRVRFEFETSLTSNKTLITVKEPFIKPTLHIKPSSNITEGKEIRFECSTVVAKMRDIEIILLRNKTILSSVRDQTTLKYSAVATLEDSGEYLCKVEEGKASKTTTHNVVVTELFPKPILTASMNELDEHKELTLSCSIKDFQNASFSILRKHSSRDILLRNSRNLTMRASVNDTGSYICKAEVNRIVKESKPVTIRVYAPVSMPSISVFSGLPEVVLGRPLNLTCCLMMGTPPITFTFYKGNKNKKKIVTNNTCAAFLDKDIRQNDKGQYKCGAKNHHSSGMKTSKVLNITVIVPIRNTSLGSVPYGVVEDGRETTFLCSVEEGSWPIHFRIFRKMDRDILLFERSEHADRVVWQKKEMSRQDTGTYYCIASNRANVSAKSHPITINVILASWQKGVITAFVLIPIAGVMILAVWWFWCKKKNAKGPSMEMSRSALATNSTSEKLSRQHNDGDYYSGSGYIEDGENHMKSTDENKVAAGSGPRLK", "length": 682, "header": "tr|A0A8V1AE85-1|A0A8V1AE85_CHICK Computationally mapped isoform of Platelet endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=PECAM1 PE=1 SV=1 CANONICAL=A0A8V1AN16-1" }, "locus": { "chromosome": "18", "start_pos": 7500863, "end_pos": 7489589, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071636.1", "url": "https://www.ensembl.org/id/ENSGALT00010071636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044326.1", "url": "https://www.ensembl.org/id/ENSGALP00010044326.1" } ] } }, { "isoform_ac": "A0A8V1AJK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16/entry#A0A8V1AJK9-1", "sequence": { "sequence": "MYLALLVIFLQCSEICTQKRVFTFNAVHIEVQPSAKVENGAPMSIICHADISKSTDFNLQHNITIFKDGKLVFMSVSGKGDARYEVPMARSSHTGDYQCAVEAGGKIKHSDSLHVWVTGMTKPILIAEKKEVFEGEVVKLRCELPEEVPPLYFVFQKMKVNSTPKQKLQEELYRNFSVVEFPVDEGDDILQFDCFGKRRVRFEFETSLTSNKTLITVKEPFIKPTLHIKPSSNITEGKEIRFECSTVVAKMRDIEIILLRNKTILSSVRDQTTLKYSAVATLEDSGEYLCKVEEGKASKTTTHNVVVTELFPKPILTASMNELDEHKELTLSCSIKDFQNASFSILRKHSSRDILLRNSRNLTMRASVNDTGSYICKAEVNRIVKESKPVTIRVYAPVSMPSISVFSGLPEVVLGRPLNLTCCLMMGTPPITFTFYKGNKNKKKIVTNNTCAAFLDKDIRQNDKGQYKCGAKNHHSSGMKTSKVLNITVIVPIRNTSLGSVPYGVVEDGRETTFLCSVEEGSWPIHFRIFRKMDRDILLFERSEHADRVVWQKKEMSRQDTGTYYCIASNRANVSAKSHPITINVILASWQKGVITAFVLIPIAGVMILAVWWFWCKKKNAKGPSMEMSRSALATNSTSEKLSRQHNDGDYYSGSGYIEDGENHMKSTDENKGPDLESAEVEYTEVEVSTLDPHRAPVQKGTETVYSEIRKANNDSVENRHSRIQGRPDAT", "length": 731, "header": "tr|A0A8V1AJK9-1|A0A8V1AN16_CHICK Computationally mapped isoform of Platelet endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=PECAM1 PE=1 SV=1 CANONICAL=A0A8V1AN16-1" }, "locus": { "chromosome": "18", "start_pos": 7500863, "end_pos": 7473856, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071633.1", "url": "https://www.ensembl.org/id/ENSGALT00010071633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044323.1", "url": "https://www.ensembl.org/id/ENSGALP00010044323.1" } ] } }, { "isoform_ac": "A0A8V1ALA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16/entry#A0A8V1ALA8-1", "sequence": { "sequence": "MYLALLVIFLQCSEICTQKRVFTFNAVHIEVQPSAKVENGAPMSIICHADISKSTDFNLQHNITIFKDGKLVFMSVSGKGDARYEVPMARSSHTGDYQCAVEAGGKIKHSDSLHVWVTGMTKPILIAEKKEVFEGEVVKLRCELPEEVPPLYFVFQKMKVNSTPKQKLQEELYRNFSVVEFPVDEGDDILQFDCFGKRRVRFEFETSLTSNKTLITVKEPFIKPTLHIKPSSNITEGKEIRFECSTVVAKMRDIEIILLRNKTILSSVRDQTTLKYSAVATLEDSGEYLCKVEEGKASKTTTHNVVVTELFPKPILTASMNELDEHKELTLSCSIKDFQNASFSILRKHSSRDILLRNSRNLTMRASVNDTGSYICKAEVNRIVKESKPVTIRVYAPVSMPSISVFSGLPEVVLGRPLNLTCCLMMGTPPITFTFYKGNKNKKKIVTNNTCAAFLDKDIRQNDKGQYKCGAKNHHSSGMKTSKVLNITVIVPIRNTSLGSVPYGVVEDGRETTFLCSVEEGSWPIHFRIFRKMDRDILLFERSEHADRVVWQKKEMSRQDTGTYYCIASNRANVSAKSHPITINVILASWQKGVITAFVLIPIAGVMILAVWWFWCKKKNAKGPSMEMSRSALATNSTSEKLSRQHNDGDYYSGSGYIEDGENHMKSTDENKGPDLESAEVEYTEVEVSTLDPHRAPVQKGTETVYSEIRKANNENTGAS", "length": 720, "header": "tr|A0A8V1ALA8-1|A0A8V1ALA8_CHICK Computationally mapped isoform of Platelet endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=PECAM1 PE=1 SV=1 CANONICAL=A0A8V1AN16-1" }, "locus": { "chromosome": "18", "start_pos": 7500863, "end_pos": 7473866, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071630.1", "url": "https://www.ensembl.org/id/ENSGALT00010071630.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044320.1", "url": "https://www.ensembl.org/id/ENSGALP00010044320.1" } ] } }, { "isoform_ac": "A0A8V1AN16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16/entry#A0A8V1AN16-1", "sequence": { "sequence": "MYLALLVIFLQCSEICTQKRVFTFNAVHIEVQPSAKVENGAPMSIICHADISKSTDFNLQHNITIFKDGKLVFMSVSGKGDARYEVPMARSSHTGDYQCAVEAGGKIKHSDSLHVWVTGMTKPILIAEKKEVFEGEVVKLRCELPEEVPPLYFVFQKMKVNSTPKQKLQEELYRNFSVVEFPVDEGDDILQFDCFGKRRVRFEFETSLTSNKTLITVKEPFIKPTLHIKPSSNITEGKEIRFECSTVVAKMRDIEIILLRNKTILSSVRDQTTLKYSAVATLEDSGEYLCKVEEGKASKTTTHNVVVTELFPKPILTASMNELDEHKELTLSCSIKDFQNASFSILRKHSSRDILLRNSRNLTMRASVNDTGSYICKAEVNRIVKESKPVTIRVYAPVSMPSISVFSGLPEVVLGRPLNLTCCLMMGTPPITFTFYKGNKNKKKIVTNNTCAAFLDKDIRQNDKGQYKCGAKNHHSSGMKTSKVLNITVIVPIRNTSLGSVPYGVVEDGRETTFLCSVEEGSWPIHFRIFRKMDRDILLFERSEHADRVVWQKKEMSRQDTGTYYCIASNRANVSAKSHPITINVILASWQKGVITAFVLIPIAGVMILAVWWFWCKKKNAKGPSMEMSRSALATNSTSEKLSRQHNDGDYYSGSGYIEDGENHMKSTDENKGPDLESAEVEYTEVEVSTLDPHRAPVQKGTETVYSEIRKANNGKVFEIDKQCITWLCSSFVAVC", "length": 736, "header": "tr|A0A8V1AN16-1|A0A8V1AN16_CHICK Isoform 1 of Platelet endothelial cell adhesion molecule OS=Gallus gallus OX=9031 GN=PECAM1 PE=1 SV=1 CANONICAL=A0A8V1AN16-1" }, "locus": { "chromosome": "18", "start_pos": 7500863, "end_pos": 7483815, 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"description": "Platelet sensitization by LDL" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": 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], "pmid": "" }, { "name": "glomerular endothelium development", "id": "GO:0072011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ], "pmid": "" }, { "name": "diapedesis", "id": "GO:0050904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ], "pmid": "" }, { "name": "neutrophil extravasation", "id": "GO:0072672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ], "pmid": "" }, { "name": "monocyte extravasation", "id": "GO:0035696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035696", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN16" } ], "pmid": "" 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALD0-1", "uniprot_ac": "A0A8V1ALD0", "uniprot_id": "A0A8V1ALD0_CHICK", "mass": { "chemical_mass": 82688.0, "monoisotopic_mass": 82688.0 }, "refseq": {}, "gene_names": [ { "name": "SPATA20", "type": "recommended", "evidence": [ { "id": "A0A8V1ALD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0" } ] } ], "protein_names": [ { "name": "Spermatosis associated 20", "type": "synonym", "evidence": [ { "id": "A0A8V1ALD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPATA20", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0", "locus": { "chromosome": "18", "start_pos": 10939878, "end_pos": 10948743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029636", "url": "https://www.ensembl.org/id/ENSGALG00010029636" } ] } } ], "crossref": [ { "id": "A0A8V1ALD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02955", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02955", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422100", "url": "https://www.ncbi.nlm.nih.gov/gene/422100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEA3", "url": "https://www.orthodb.org/?gene=A0A8V1AEA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJN0", "url": "https://www.orthodb.org/?gene=A0A8V1AJN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALD0", "url": "https://www.orthodb.org/?gene=A0A8V1ALD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN33", "url": "https://www.orthodb.org/?gene=A0A8V1AN33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APK5", "url": "https://www.orthodb.org/?gene=A0A8V1APK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42899:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42899:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN33", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFAAPLRRAGRPVFLAGSVAMATAGRSSPPRRANRLIYERSPYLQQHAHNPVDWYPWGQEAFDKAKRENKLIFLSVGYSTCHWCHVMEEESFKNQEIGEIMSKNFVCIKVDREERPDVDKVYMTFVQATSGGGGWPMSVWLTPDLRPFVGGTYFPPEDSAHHVGFRTVLLRIAEQWRQNQEALLQSSQRILEALRSLSRVGTQDQQAAPPAQEVLTTCFQQLSGSYDEEYGGFSQCPKFPTPVNLNFLFTYWALHRTTPEGARALQMSLHTLKMMAHGGIHDHIGQGFHRYSTDRHWHVPHFEKMLYDQGQLAVVYSRAFQISGDEFFADVAADILLYASRDLGSPAGGFYSAEDADSYPTATSSEKREGAFCVWAAEEVRALLPDPVEGAADGTTLGDVFMHYYGVKEDGNVSPRKDPHKELQGKNVLIAHSSPELTAAHFGLEPGQLSAVLQEGRRRLQAARAQRPRPHLDTKMLASWNGLMISGFAQAGAVLAKQEYVSRAAQAAGFVRRHLWEPGSGRLLRSCYRGEADVVEQSAAPIHGFLEDYVFVIQGLFDLYEASLDQSWLEWALQLQHTQDKLFWDPKGFAYFSSEAGDPSLLLRLKDDQDGAEPAANSVTVTNLLRAASYSGHMEWVEKAGQILAAFSERLQKIPLALPEMARATAVFHHTLKQVVICGDPQGEDTKEMLSCVHSTFIPNKGRRCDQMPPTPSLPSPWLCLPWGRRDGSRSWLRSRPY", "length": 738, "header": "tr|A0A8V1ALD0-1|A0A8V1ALD0_CHICK Isoform 1 of Spermatosis associated 20 OS=Gallus gallus OX=9031 GN=SPATA20 PE=1 SV=1 CANONICAL=A0A8V1ALD0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0/entry#A0A8V1AEA3-1", "sequence": { "sequence": "MATAGRSSPPRRANRLIYERSPYLQQHAHNPVDWYPWGQEAFDKAKRENKLIFLSVGYSTCHWCHVMEEESFKNQEIGEIMSKNFVCIKVDREERPDVDKVYMTFVQATSGGGGWPMSVWLTPDLRPFVGGTYFPPEDSAHHVGFRTVLLRIAEQWRQNQEALLQSSQRILEALRSLSRVGTQDQQAAPPAQEVLTTCFQQLSGSYDEEYGGFSQCPKFPTPVNLNFLFTYWALHRTTPEGARALQMSLHTLKMMAHGGIHDHIGQGFHRYSTDRHWHVPHFEKMLYDQGQLAVVYSRAFQISGDEFFADVAADILLYASRDLGSPAGGFYSAEDADSYPTATSSEKREGAFCVWAAEEVRALLPDPVEGAADGTTLGDVFMHYYGVKEDGNVSPRKDPHKELQGKNVLIAHSSPELTAAHFGLEPGQLSAVLQEGRRRLQAARAQRPRPHLDTKMLASWNGLMISGFAQAGAVLAKQEYVSRAAQAAGFVRRHLWEPGSGRLLRSCYRGEADVVEQSAAPIHGFLEDYVFVIQGLFDLYEASLDQSWLEWALQLQHTQDKLFWDPKGFAYFSSEAGDPSLLLRLKDDQDGAEPAANSVTVTNLLRAASYSGHMEWVEKAGQILAAFSERLQKIPLALPEMARATAVFHHTLKQVVICGDPQGEDTKEMLSCVHSTFIPNKVLILADGDGAGFLYRQLPFLSSLERKEGKATAYVCSNFTCSLPVTSPCALQELLCA", "length": 737, "header": "tr|A0A8V1AEA3-1|A0A8V1AEA3_CHICK Computationally mapped isoform of Spermatosis associated 20 OS=Gallus gallus OX=9031 GN=SPATA20 PE=1 SV=1 CANONICAL=A0A8V1ALD0-1" }, "locus": { "chromosome": "18", "start_pos": 10947860, "end_pos": 10941079, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071656.1", "url": "https://www.ensembl.org/id/ENSGALT00010071656.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044346.1", "url": "https://www.ensembl.org/id/ENSGALP00010044346.1" } ] } }, { "isoform_ac": "A0A8V1AJN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0/entry#A0A8V1AJN0-1", "sequence": { "sequence": "MFAAPLRRAGRYPWGQEAFDKAKRENKLIFLSVGYSTCHWCHVMEEESFKNQEIGEIMSKNFVCIKVDREERPDVDKVYMTFVQATSGGGGWPMSVWLTPDLRPFVGGTYFPPEDSAHHVGFRTVLLRIAEQWRQNQEALLQSSQRILEALRSLSRVGTQDQQAAPPAQEVLTTCFQQLSGSYDEEYGGFSQCPKFPTPVNLNFLFTYWALHRTTPEGARALQMSLHTLKMMAHGGIHDHIGQGFHRYSTDRHWHVPHFEKMLYDQGQLAVVYSRAFQISGDEFFADVAADILLYASRDLGSPAGGFYSAEDADSYPTATSSEKREGAFCVWAAEEVRALLPDPVEGAADGTTLGDVFMHYYGVKEDGNVSPRKDPHKELQGKNVLIAHSSPELTAAHFGLEPGQLSAVLQEGRRRLQAARAQRPRPHLDTKMLASWNGLMISGFAQAGAVLAKQEYVSRAAQAAGFVRRHLWEPGSGRLLRSCYRGEADVVEQSAAPIHGFLEDYVFVIQGLFDLYEASLDQSWLEWALQLQHTQDKLFWDPKGFAYFSSEAGDPSLLLRLKDDQDGAEPAANSVTVTNLLRAASYSGHMEWVEKAGQILAAFSERLQKIPLALPEMARATAVFHHTLKQVVICGDPQGEDTKEMLSCVHSTFIPNKVLILADGDGAGFLYRQLPFLSSLERKEGKATAYVCSNFTCSLPVTSPCALQELLCA", "length": 714, "header": "tr|A0A8V1AJN0-1|A0A8V1ALD0_CHICK Computationally mapped isoform of Spermatosis associated 20 OS=Gallus gallus OX=9031 GN=SPATA20 PE=1 SV=1 CANONICAL=A0A8V1ALD0-1" }, "locus": { "chromosome": "18", "start_pos": 10948734, "end_pos": 10941079, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071658.1", "url": "https://www.ensembl.org/id/ENSGALT00010071658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044348.1", "url": "https://www.ensembl.org/id/ENSGALP00010044348.1" } ] } }, { "isoform_ac": "A0A8V1ALD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0/entry#A0A8V1ALD0-1", "sequence": { "sequence": "MFAAPLRRAGRPVFLAGSVAMATAGRSSPPRRANRLIYERSPYLQQHAHNPVDWYPWGQEAFDKAKRENKLIFLSVGYSTCHWCHVMEEESFKNQEIGEIMSKNFVCIKVDREERPDVDKVYMTFVQATSGGGGWPMSVWLTPDLRPFVGGTYFPPEDSAHHVGFRTVLLRIAEQWRQNQEALLQSSQRILEALRSLSRVGTQDQQAAPPAQEVLTTCFQQLSGSYDEEYGGFSQCPKFPTPVNLNFLFTYWALHRTTPEGARALQMSLHTLKMMAHGGIHDHIGQGFHRYSTDRHWHVPHFEKMLYDQGQLAVVYSRAFQISGDEFFADVAADILLYASRDLGSPAGGFYSAEDADSYPTATSSEKREGAFCVWAAEEVRALLPDPVEGAADGTTLGDVFMHYYGVKEDGNVSPRKDPHKELQGKNVLIAHSSPELTAAHFGLEPGQLSAVLQEGRRRLQAARAQRPRPHLDTKMLASWNGLMISGFAQAGAVLAKQEYVSRAAQAAGFVRRHLWEPGSGRLLRSCYRGEADVVEQSAAPIHGFLEDYVFVIQGLFDLYEASLDQSWLEWALQLQHTQDKLFWDPKGFAYFSSEAGDPSLLLRLKDDQDGAEPAANSVTVTNLLRAASYSGHMEWVEKAGQILAAFSERLQKIPLALPEMARATAVFHHTLKQVVICGDPQGEDTKEMLSCVHSTFIPNKGRRCDQMPPTPSLPSPWLCLPWGRRDGSRSWLRSRPY", "length": 738, "header": "tr|A0A8V1ALD0-1|A0A8V1ALD0_CHICK Isoform 1 of Spermatosis associated 20 OS=Gallus gallus OX=9031 GN=SPATA20 PE=1 SV=1 CANONICAL=A0A8V1ALD0-1" }, "locus": { "chromosome": "18", "start_pos": 10948734, "end_pos": 10941724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071660.1", "url": "https://www.ensembl.org/id/ENSGALT00010071660.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044350.1", "url": "https://www.ensembl.org/id/ENSGALP00010044350.1" } ] } }, { "isoform_ac": "A0A8V1AN33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0/entry#A0A8V1AN33-1", "sequence": { "sequence": "MATAGRSSPPRRANRLIYERSPYLQQHAHNPVDWYPWGQEAFDKAKRENKLIFLSVGYSTCHWCHVMEEESFKNQEIGEIMSKNFVCIKVDREERPDVDKVYMTFVQATSGGGGWPMSVWLTPDLRPFVGGTYFPPEDSAHHVGFRTVLLRIAEQWRQNQEALLQSSQRILEALRSLSRVGTQDQQAAPPAQEVLTTCFQQLSGSYDEEYGGFSQCPKFPTPVNLNFLFTYWALHRTTPEGARALQMSLHTLKMMAHGGIHDHIGQGFHRYSTDRHWHVPHFEKMLYDQGQLAVVYSRAFQISGDEFFADVAADILLYASRDLGSPAGGFYSAEDADSYPTATSSEKREGAFCVWAAEEVRALLPDPVEGAADGTTLGDVFMHYYGVKEDGNVSPRKDPHKELQGKNVLIAHSSPELTAAHFGLEPGQLSAVLQEGRRRLQAARAQRPRPHLDTKMLASWNGLMISGFAQAGAVLAKQEYVSRAAQAAGFVRRHLWEPGSGRLLRSCYRGEADVVEQSAAPIHGFLEDYVFVIQGLFDLYEASLDQSWLEWALQLQHTQDKLFWDPKGFAYFSSEAGDPSLLLRLKDGAWGPWAEQGWSWRWADVTPCPLQTRMEQSPLPTLLLSQTCSEQPRIPATWSGWKRLGRSWLPSLRGCRRSRWPCPRWPGPLPCSITPSNRW", "length": 679, "header": "tr|A0A8V1AN33-1|A0A8V1AN33_CHICK Computationally mapped isoform of Spermatosis associated 20 OS=Gallus gallus OX=9031 GN=SPATA20 PE=1 SV=1 CANONICAL=A0A8V1ALD0-1" }, "locus": { "chromosome": "18", "start_pos": 10947860, "end_pos": 10943426, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071659.1", "url": "https://www.ensembl.org/id/ENSGALT00010071659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044349.1", "url": "https://www.ensembl.org/id/ENSGALP00010044349.1" } ] } }, { "isoform_ac": "A0A8V1APK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0/entry#A0A8V1APK5-1", "sequence": { "sequence": "MATAGRSSPPRRANRLIYERSPYLQQHAHNPVDWYPWGQEAFDKAKRENKLIFLSVGYSTCHWCHVMEEESFKNQEIGEIMSKNFVCIKVDREERPDVDKVYMTFVQATSGGGGWPMSVWLTPDLRPFVGGTYFPPEDSAHHVGFRTVLLRIAEQWRQNQEALLQSSQRILEALRSLSRVGTQDQQAAPPAQEVLTTCFQQLSGSYDEEYGGFSQCPKFPTPVNLNFLFTYWALHRTTPEGARALQMSLHTLKMMAHGGIHDHIGQGFHRYSTDRHWHVPHFEKMLYDQGQLAVVYSRAFQISGDEFFADVAADILLYASRDLGSPAGGFYSAEDADSYPTATSSEKREGAFCVWAAEEVRALLPDPVEGAADGTTLGDVFMHYYGVKEDGNVSPRKDPHKELQGKNVLIAHSSPELTAAHFGLEPGQLSAVLQEGRRRLQAARAQRPRPHLDTKMLASWNGLMISGFAQAGAVLAKQEYVSRAAQAAGFVRRHLWEPGSGRLLRSCYRGEADVVEQSAAPIHGFLEDYVFVIQGLFDLYEASLDQSWLEWALQLQHTQDKLFWDPKGFAYFSSEAGDPSLLLRLKDDQDGAEPAANSVTVTNLLRAASYSGHMEWVEKAGQILAAFSERLQKIPLALPEMARATAVFHHTLKQVLILADGDGAGFLYRQLPFLSSLERKEGKATAYVCSNFTCSLPVTSPCALQELLCA", "length": 710, "header": "tr|A0A8V1APK5-1|A0A8V1APK5_CHICK Computationally mapped isoform of Spermatosis associated 20 OS=Gallus gallus OX=9031 GN=SPATA20 PE=1 SV=1 CANONICAL=A0A8V1ALD0-1" }, "locus": { "chromosome": "18", "start_pos": 10947860, "end_pos": 10941079, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071657.1", "url": "https://www.ensembl.org/id/ENSGALT00010071657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044347.1", "url": "https://www.ensembl.org/id/ENSGALP00010044347.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 711, "start_aa": "Thr", "end_pos": 711, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr711", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD0" }, { "id": "PF03190", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03190" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spermatogenesis-associated protein 20-like TRX", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 194, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 711 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 412, "end_pos": 414 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AN75-1", "uniprot_ac": "A0A8V1AN75", "uniprot_id": "A0A8V1AN75_CHICK", "mass": { "chemical_mass": 34405.0, "monoisotopic_mass": 34405.0 }, "refseq": { "ac": "XP_024997631", "name": "ras-related protein Rab-37 isoform X12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997631" }, "gene_names": [ { "name": "RAB37", "type": "recommended", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ] }, { "name": "RAB37", "type": "synonym", "evidence": [ { "id": "XP_024997631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997631" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1AN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-37 isoform X12", "type": "synonym", "evidence": [ { "id": "XP_024997631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997631" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997631.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997631" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB37", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75", "locus": { "chromosome": "18", "start_pos": 11071128, "end_pos": 11059156, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029664", "url": "https://www.ensembl.org/id/ENSGALG00010029664" } ] } } ], "crossref": [ { "id": "A0A8V1AN75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AN75", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859318", "url": "https://www.ncbi.nlm.nih.gov/gene/100859318", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QAPPEHG", "url": "https://omabrowser.org/oma/group/QAPPEHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEG0", "url": "https://www.orthodb.org/?gene=A0A8V1AEG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEG5", "url": "https://www.orthodb.org/?gene=A0A8V1AEG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJT8", "url": "https://www.orthodb.org/?gene=A0A8V1AJT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJU2", "url": "https://www.orthodb.org/?gene=A0A8V1AJU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALH6", "url": "https://www.orthodb.org/?gene=A0A8V1ALH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALI0", "url": "https://www.orthodb.org/?gene=A0A8V1ALI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN75", "url": "https://www.orthodb.org/?gene=A0A8V1AN75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN77", "url": "https://www.orthodb.org/?gene=A0A8V1AN77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APP0", "url": "https://www.orthodb.org/?gene=A0A8V1APP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APP4", "url": "https://www.orthodb.org/?gene=A0A8V1APP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024997631", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997631", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AEG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN77", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQREDSAAPERLCALTTHSGCCVQQPGETLSLLNHSGPRPALPDSSFLGRAVQTEISSPMYRAPRSARGRVCALQTLRMPGVPPQTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 314, "header": "tr|A0A8V1AN75-1|A0A8V1AN75_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1AEG0-1", "sequence": { "sequence": "MGPKDSRWDRPSMGSAGLLWRWAGGPGANQSEGLRAPRWALPAVTPAALTRGLGWGFAERDFQGGNRAGAQPGWRRCPRRRKRRRKEGQDSAALLGHTMSGAGGNGTPQVSPQEYELAGKVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 312, "header": "tr|A0A8V1AEG0-1|A0A8V1AEG0_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11065918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071721.1", "url": "https://www.ensembl.org/id/ENSGALT00010071721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044411.1", "url": "https://www.ensembl.org/id/ENSGALP00010044411.1" } ] } }, { "isoform_ac": "A0A8V1AEG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1AEG5-1", "sequence": { "sequence": "MHDFASNAQTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTGGNRAGAQPGWRRCPRRRKRRRKEGQDSAALLGHTMSGAGGNGTPQVSPQEYELAGKVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 295, "header": "tr|A0A8V1AEG5-1|A0A8V1AEG5_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11063759, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071726.1", "url": "https://www.ensembl.org/id/ENSGALT00010071726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044416.1", "url": "https://www.ensembl.org/id/ENSGALP00010044416.1" } ] } }, { "isoform_ac": "A0A8V1AJT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1AJT8-1", "sequence": { "sequence": "MGPKDSRWDRPSMGSAGLLWRWAGGPGANQSEGLRAPRWALPAVTPAALTRGLGWGFAERDFQVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 255, "header": "tr|A0A8V1AJT8-1|A0A8V1AN75_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11065918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071723.1", "url": "https://www.ensembl.org/id/ENSGALT00010071723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044413.1", "url": "https://www.ensembl.org/id/ENSGALP00010044413.1" } ] } }, { "isoform_ac": "A0A8V1AJU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1AJU2-1", "sequence": { "sequence": "MEARAAGSAGTGYNEALLHKTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTGGNRAGAQPGWRRCPRRRKRRRKEGQDSAALLGHTMSGAGGNGTPQVSPQEYELAGKVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 306, "header": "tr|A0A8V1AJU2-1|A0A8V1AN75_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11060785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071728.1", "url": "https://www.ensembl.org/id/ENSGALT00010071728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044418.1", "url": "https://www.ensembl.org/id/ENSGALP00010044418.1" } ] } }, { "isoform_ac": "A0A8V1ALH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1ALH6-1", "sequence": { "sequence": "MLECPHSRAGLRGGNRAGAQPGWRRCPRRRKRRRKEGQDSAALLGHTMSGAGGNGTPQVSPQEYELAGKVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 261, "header": "tr|A0A8V1ALH6-1|A0A8V1ALH6_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11066370, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071720.1", "url": "https://www.ensembl.org/id/ENSGALT00010071720.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044410.1", "url": "https://www.ensembl.org/id/ENSGALP00010044410.1" } ] } }, { "isoform_ac": "A0A8V1ALI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1ALI0-1", "sequence": { "sequence": "MQREDSAAPERLCALTTHSGCCVQQPGETLSLLNHSGPRPALPDSSFLGRAVQTEISSPMYRAPRSARGRVCALQTLRMPGVPPQTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 277, "header": "tr|A0A8V1ALI0-1|A0A8V1ALI0_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11064109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071725.1", "url": "https://www.ensembl.org/id/ENSGALT00010071725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044415.1", "url": "https://www.ensembl.org/id/ENSGALP00010044415.1" } ] } }, { "isoform_ac": "A0A8V1AN75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1AN75-1", "sequence": { "sequence": "MQREDSAAPERLCALTTHSGCCVQQPGETLSLLNHSGPRPALPDSSFLGRAVQTEISSPMYRAPRSARGRVCALQTLRMPGVPPQTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 314, "header": "tr|A0A8V1AN75-1|A0A8V1AN75_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11064109, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071724.1", "url": "https://www.ensembl.org/id/ENSGALT00010071724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044414.1", "url": "https://www.ensembl.org/id/ENSGALP00010044414.1" } ] } }, { "isoform_ac": "A0A8V1AN77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1AN77-1", "sequence": { "sequence": "MTQEMKTNSAGTESSQRTSSKLFLQQRCARNPHPEVSRAAASDLVLFGGLHSSLLGTLSWPWPATNPLAHWTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 263, "header": "tr|A0A8V1AN77-1|A0A8V1AN77_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11059228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071729.1", "url": "https://www.ensembl.org/id/ENSGALT00010071729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044419.1", "url": "https://www.ensembl.org/id/ENSGALP00010044419.1" } ] } }, { "isoform_ac": "A0A8V1APP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1APP0-1", "sequence": { "sequence": "MGPKDSRWDRPSMGSAGLLWRWAGGPGANQSEGLRAPRWALPAVTPAALTRGLGWGFAERDFQGGNRAGAQPGWRRCPRRRKRRRKEGQDSAALLGHTMSGAGGNGTPQVSPQEYELAGKNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 275, "header": "tr|A0A8V1APP0-1|A0A8V1APP0_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11065918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071722.1", "url": "https://www.ensembl.org/id/ENSGALT00010071722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044412.1", "url": "https://www.ensembl.org/id/ENSGALP00010044412.1" } ] } }, { "isoform_ac": "A0A8V1APP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75/entry#A0A8V1APP4-1", "sequence": { "sequence": "MTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTGGNRAGAQPGWRRCPRRRKRRRKEGQDSAALLGHTMSGAGGNGTPQVSPQEYELAGKVMLLGDSGVGKTCFLLQFKDGAFLSGTFIATVGIDFRNKVVAVDGVKVKLQIWDTAGQERFRSVTHAYYRDAQALLLLYDITSKMSFDNIRAWLTEIHEYAQKDVVIMLLGNKADVSSERMVRTEDGASLAREYGVPFMETSAKTGMNVELAFLAIARELKQRAVQPPDEPRFQIHDYIEAQQKRSGCCAFI", "length": 287, "header": "tr|A0A8V1APP4-1|A0A8V1APP4_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB37 PE=3 SV=1 CANONICAL=A0A8V1AN75-1" }, "locus": { "chromosome": "18", "start_pos": 11070257, "end_pos": 11063139, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071727.1", "url": "https://www.ensembl.org/id/ENSGALT00010071727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044417.1", "url": "https://www.ensembl.org/id/ENSGALP00010044417.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" }, { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-6798739", "name": "Exocytosis of azurophil granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, azurophil granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A3Q2U2N5-1", "Q98932-1", "A0A1D5PVG8-1", "Q5ZHX1-1", "A0A8V1AN75-1", "A0A8V0Z1E9-1", "A0A8V0YYJ1-1", "A0A8V0ZEG9-1", "A0A3Q2UE42-1", "A0A8V0Y298-1", "A0A8V0YGN2-1" ], "evidence": [ { "id": "R-GGA-6798739", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798739" } ] }, { "id": "R-GGA-6799350", "name": "Exocytosis of specific granule membrane proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, specific granule membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XBX5-1", "A0A3Q2U2N5-1", "A0A8V1AKE3-1", "P15120-1", "A0A1D5P3W4-1", "Q5F3C1-1", "A0A8V1AN75-1", "A0A8V0ZZE4-1", "F1NSA8-1", "A0A8V0YXK7-1", "A0A8V0Y5N7-1", "A0A8V0YIN5-1", "A0A8V0YJI3-1", "A0A8V0YMC7-1" ], "evidence": [ { "id": "R-GGA-6799350", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799350" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": 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"A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1D5PVG8", "gene_name": "PRCP", "activity": [ { "ec_number": "3.4.16.2", "activity": "Cleavage of a -Pro-|-Xaa bond to release a C-terminal amino acid.", "evidence": [ { "id": "A0A1D5PVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVG8" } ] }, { "ec_number": "3.4.16.2", "activity": "", "evidence": [ { "id": "A0A1D5PVG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVG8" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2U2N5", "gene_name": "ATP8A1", "activity": [ { "ec_number": "7.6.2.1", "activity": "ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] }, { "ec_number": "7.6.2.1", "activity": "", "evidence": [ { "id": "A0A3Q2U2N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2N5" } ] } ] }, { "uniprot_ac": "A0A3Q2UE42", "gene_name": "PSEN1", "activity": [ { "ec_number": "3.4.23.-", "activity": "", "evidence": [ { "id": "A0A3Q2UE42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UE42" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y298", "gene_name": "B4GALT1", "activity": [ { "ec_number": "2.4.1.90", "activity": "N-acetyl-D-glucosamine + UDP-alpha-D-galactose = beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + UDP + H(+).", "evidence": [ { "id": "A0A8V0Y298", "database": 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"activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Y4A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y5N7", "gene_name": "BST1", "activity": [ { "ec_number": "3.2.2.6", "activity": "NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+).", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] }, { "ec_number": "3.2.2.6", "activity": "", "evidence": [ { "id": "A0A8V0Y5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5N7" } ] } ] }, { "uniprot_ac": "A0A8V0Y9R6", "gene_name": "RAP1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y9R6", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDI7" } ] } ] }, { "uniprot_ac": "A0A8V0YDX6", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YDX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDX6" } ] } ] }, { "uniprot_ac": "A0A8V0YGN2", "gene_name": "MGST1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A0A8V0YGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN2" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "A0A8V0YGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN2" } ] } ] }, { "uniprot_ac": "A0A8V0YGN8", "gene_name": "RAB21", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGN8" } ] } ] }, { "uniprot_ac": "A0A8V0YHK2", "gene_name": "RAC2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0YHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHK2" } ] } ] }, { "uniprot_ac": "A0A8V0YIM0", "gene_name": "SAR1B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + 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"Q90965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90965" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q90965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q90965" } ] } ] }, { "uniprot_ac": "Q98932", "gene_name": "RAB5C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q98932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98932" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q98932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98932" } ] } ] }, { "uniprot_ac": "Q9PSX7", "gene_name": "RHOC", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9PSX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PSX7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9PSX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PSX7" } ] } ] }, { "uniprot_ac": "R4GJA4", "gene_name": "LOC770492", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "R4GJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "R4GJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJA4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.5.2", "ec_name": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "3.6.5.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.5.2" }, { "id": "3.6.5.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.5.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALZ1-1", "uniprot_ac": "A0A8V1ALZ1", "uniprot_id": "A0A8V1ALZ1_CHICK", "mass": { "chemical_mass": 116326.0, "monoisotopic_mass": 116326.0 }, "refseq": { "ac": "XP_015151443", "name": "CAP-Gly domain-containing linker protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151443" }, "gene_names": [ { "name": "CLIP2", "type": "recommended", "evidence": [ { "id": "A0A8V1ALZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ] }, { "name": "CLIP2", "type": "synonym", "evidence": [ { "id": "XP_015151443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151443" } ] } ], "protein_names": [ { "name": "CAP-Gly domain containing linker protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ALZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1/entry#names_and_taxonomy" } ] }, { "name": "CAP-Gly domain-containing linker protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151443" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151443" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1", "locus": { "chromosome": "19", "start_pos": 3260600, "end_pos": 3318000, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029385", "url": "https://www.ensembl.org/id/ENSGALG00010029385" } ] } } ], "crossref": [ { "id": "A0A8V1ALZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "417488", "url": "https://www.ncbi.nlm.nih.gov/gene/417488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417488", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417488", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMIESSD", "url": "https://omabrowser.org/oma/group/HMIESSD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJZ4", "url": "https://www.orthodb.org/?gene=A0A8V1AJZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALZ1", "url": "https://www.orthodb.org/?gene=A0A8V1ALZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKPSGLKIPGRAGKHSSPVGRASGTAAATVTTGTKEGSPLHKQSATSTSSADKSGSKAAEVGDDFLGDFVVGERVWVNGVKPGVIQYLGETQFAPGQWAGVVLDDPVGKNDGSVGGVRYFECQPLQGIFTRPSKLTRQPVAEGSGSDVPSVDSLTAQNLSLHSGTATPPLSTRVIPLRESVLNSAMKTGNESGSNLSDSGSVKKGEKDLRLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKSKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIAIMKAQHEQYVTEAEGNLQRARALVDGMQKEKIELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTQLEHARIRELEQSLLFEKAQAEKLLRELEDTRLTTVAEQSRILQLEEELSLRRSEVDELRQCLRSSHQAETPEHSLGLQSEALRLRDQLLSANKEHQKESSQLKEKYEKTLKKYQQEMEKLKAVNEKYSQEIVDLKHKVQQATNENMGLMDNWKSKLDTLASDHQKSLEDLKATLNTGPDTQHKEIVELKAVVESIKMEHQLELENLKAKHDIETAVHIKEKESLKLKLQEAVDEVEKSNSNWKMQLETKSNQHLLELQDVKDKCRDAELRVHELEKLHSEYKDQTQAIAFLKEQISLAEKKMLDYETLQKTEAQSKQEIHRLQEKVLVLENKLQSMEALHPSQHANMIETNDISEEKIRMKQTMEDLQDKLSKRDKEVSSLVSQTEALRAQVSALENKCKTMEKKADSVLKEKKRLEGELEALTKKTHDASGQLVLISQELLKKERSLNELRALLLEANRHSPGPERDLSREVHKAEWRLKEQKLKDDIKGLREKLVVLDKEKAVTDQRRYSLIDPSSESEVIRLQHRLVSTEDVLRNALEQGHQMEKLMEAMRLSSEKTQPVGNSGSANGIHQQDKSHKQEEKL", "length": 1040, "header": "tr|A0A8V1ALZ1-1|A0A8V1ALZ1_CHICK Isoform 1 of CAP-Gly domain containing linker protein 2 OS=Gallus gallus OX=9031 GN=CLIP2 PE=1 SV=1 CANONICAL=A0A8V1ALZ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AJZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1/entry#A0A8V1AJZ4-1", "sequence": { "sequence": "MLKPSGLKIPGRAGKHSSPVGRASGTAAATVTTGTKEGSPLHKQSATSTSSADKSGSKAAEVGDDFLGDFVVGERVWVNGVKPGVIQYLGETQFAPGQWAGVVLDDPVGKNDGSVGGVRYFECQPLQGIFTRPSKLTRQPVAEGSGSDVPSVDSLTAQNLSLHSGTATPPLSTRVIPLRESVLNSAMKTGNESGSNLSDSGSVKKGEKDLRLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKSKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIAIMKAQHEQYVTEAEGNLQRARALVDGMQKEKIELLNQLEEEKRKVEDLQFRVEEESITKGDLELTTVAEQSRILQLEEELSLRRSEVDELRQCLRSSHQAETPEHSLGLQSEALRLRDQLLSANKEHQKESSQLKEKYEKTLKKYQQEMEKLKAVNEKYSQEIVDLKHKVQQATNENMGLMDNWKSKLDTLASDHQKSLEDLKATLNTGPDTQHKEIVELKAVVESIKMEHQLELENLKAKHDIETAVHIKEKESLKLKLQEAVDEVEKSNSNWKMQLETKSNQHLLELQDVKDKCRDAELRVHELEKLHSEYKDQTQAIAFLKEQISLAEKKMLDYETLQKTEAQSKQEIHRLQEKVLVLENKLQSMEALHPSQHANMIETNDISEEKIRMKQTMEDLQDKLSKRDKEVSSLVSQTEALRAQVSALENKCKTMEKKADSVLKEKKRLEGELEALTKKTHDASGQLVLISQELLKKERSLNELRALLLEANRHSPGPERDLSREVHKAEWRLKEQKLKDDIKGLREKLVVLDKEKAVTDQRRYSLIDPSSESEVIRLQHRLVSTEDVLRNALEQGHQMEKLMEAMRLSSEKTQPVGNSGSANGIHQQDKSHKQEEKL", "length": 1005, "header": "tr|A0A8V1AJZ4-1|A0A8V1ALZ1_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein 2 OS=Gallus gallus OX=9031 GN=CLIP2 PE=1 SV=1 CANONICAL=A0A8V1ALZ1-1" }, "locus": { "chromosome": "19", "start_pos": 3307002, "end_pos": 3263594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071073.1", "url": "https://www.ensembl.org/id/ENSGALT00010071073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043764.1", "url": "https://www.ensembl.org/id/ENSGALP00010043764.1" } ] } }, { "isoform_ac": "A0A8V1ALZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1/entry#A0A8V1ALZ1-1", "sequence": { "sequence": "MLKPSGLKIPGRAGKHSSPVGRASGTAAATVTTGTKEGSPLHKQSATSTSSADKSGSKAAEVGDDFLGDFVVGERVWVNGVKPGVIQYLGETQFAPGQWAGVVLDDPVGKNDGSVGGVRYFECQPLQGIFTRPSKLTRQPVAEGSGSDVPSVDSLTAQNLSLHSGTATPPLSTRVIPLRESVLNSAMKTGNESGSNLSDSGSVKKGEKDLRLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKSKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIAIMKAQHEQYVTEAEGNLQRARALVDGMQKEKIELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTQLEHARIRELEQSLLFEKAQAEKLLRELEDTRLTTVAEQSRILQLEEELSLRRSEVDELRQCLRSSHQAETPEHSLGLQSEALRLRDQLLSANKEHQKESSQLKEKYEKTLKKYQQEMEKLKAVNEKYSQEIVDLKHKVQQATNENMGLMDNWKSKLDTLASDHQKSLEDLKATLNTGPDTQHKEIVELKAVVESIKMEHQLELENLKAKHDIETAVHIKEKESLKLKLQEAVDEVEKSNSNWKMQLETKSNQHLLELQDVKDKCRDAELRVHELEKLHSEYKDQTQAIAFLKEQISLAEKKMLDYETLQKTEAQSKQEIHRLQEKVLVLENKLQSMEALHPSQHANMIETNDISEEKIRMKQTMEDLQDKLSKRDKEVSSLVSQTEALRAQVSALENKCKTMEKKADSVLKEKKRLEGELEALTKKTHDASGQLVLISQELLKKERSLNELRALLLEANRHSPGPERDLSREVHKAEWRLKEQKLKDDIKGLREKLVVLDKEKAVTDQRRYSLIDPSSESEVIRLQHRLVSTEDVLRNALEQGHQMEKLMEAMRLSSEKTQPVGNSGSANGIHQQDKSHKQEEKL", "length": 1040, "header": "tr|A0A8V1ALZ1-1|A0A8V1ALZ1_CHICK Isoform 1 of CAP-Gly domain containing linker protein 2 OS=Gallus gallus OX=9031 GN=CLIP2 PE=1 SV=1 CANONICAL=A0A8V1ALZ1-1" }, "locus": { "chromosome": "19", "start_pos": 3307002, "end_pos": 3263594, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071072.1", "url": "https://www.ensembl.org/id/ENSGALT00010071072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043763.1", "url": "https://www.ensembl.org/id/ENSGALP00010043763.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417488", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417488", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O55156-1", "protein_name": "CAP-Gly domain-containing linker protein 2", "gene_name": "Clip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQKPSGLKPPGRGGKHSSPVGRPSIGSASSSVVASASGSKEGSPLHKQASGPSSAGATTTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGLRYFECPALQGIFTRPSKLTRQPAAEGSGSDGHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGDKDLHLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPEAAETLRLRERLLSASKEHQRDSTLLQDKYEHMLKTYQTEVDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKALVEGIKMEHQLELGNLQAKHDLETAMHGKEKEGLRQKLQEAQEELAGLQQHWRAQLEEQAAAPAELQEAQDQCRDAQLRVQELEGLDVEYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAVESLCSAQHSHVIESNDLSEEKIRMKETVEGLQDKLNKRDKEVAALTSQMDMLRAQVSALENKCKSGEKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLREKLTGLDKEKSLSEQKRYSLIDPASAPELLRLQHQLVSTEGCLRDALDQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH", "length": 1046 }, "evidence": [ { "id": "A0A8V1ALZ1", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UDT6-1", "protein_name": "CAP-Gly domain-containing linker protein 2", "gene_name": "CLIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKPSGLKPPGRGGKHSSPMGRTSTGSASSSAAVAASSKEGSPLHKQSSGPSSSPAAAAAPEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDAHSVESLTAQNLSLHSGTATPPLTSRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGEKDLRLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVESVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELTLRRGEIEELQQCLLHSGPPPPDHPDAAEILRLRERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEVAGLKDKVQQATSENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKAVMEGIKMEHQLELGNLQAKHDLETAMHVKEKEALREKLQEAQEELAGLQRHWRAQLEVQASQHRLELQEAQDQRRDAELRVHELEKLDVEYRGQAQAIEFLKEQISLAEKKMLDYERLQRAEAQGKQEVESLREKLLVAENRLQAVEALCSSQHTHMIESNDISEETIRTKETVEGLQDKLNKRDKEVTALTSQTEMLRAQVSALESKCKSGEKKVDALLKEKRRLEAELETVSRKTHDASGQLVLISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLREKLTGLDKEKSLSDQRRYSLIDRSSAPELLRLQHQLMSTEDALRDALDQAQQVEKLMEAMRSCPDKAQTIGNSGSANGIHQQDKAQKQEDKH", "length": 1046 }, "evidence": [ { "id": "A0A8V1ALZ1", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z0H8-1", "protein_name": "CAP-Gly domain-containing linker protein 2", "gene_name": "Clip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQKPSGLKPPGRGGKHSSPVGRPSVGSASSSVVASTSGSKEGSPLHKQASGPSSSGAATTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDTHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGDKDLHLGDRVLVGGTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPEAAETLRLRERLLSASKEHQRDSTLLQDKYEHMLKTYQTEVDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKALVEGIKMEHQLELGNLQAKHDLETAMHGKEKEGLRQKLQEVQEELAGLQQHWREQLEEQASQHRLELQEAQDQCRDAQLRAQELEGLDVEYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAAESLCSAQHSHVIESSDLSEETIRMKETVEGLQDKLNKRDKEVTALTSQMDMLRAQVSALENKCKSGEKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLREKLTGLDKEKSLSEQRRYSLIDPASPPELLKLQHQLVSTEDALRDALNQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH", "length": 1047 }, "evidence": [ { "id": "A0A8V1ALZ1", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ], "pmid": "" }, { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule plus-end binding", "id": "GO:0051010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ1" }, { "id": "PS50245", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50245" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAP-Gly", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 132, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 196, "end_pos": 198 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1APT0-1", "uniprot_ac": "A0A8V1APT0", "uniprot_id": "A0A8V1APT0_CHICK", "mass": { "chemical_mass": 100011.0, "monoisotopic_mass": 100011.0 }, "refseq": {}, "gene_names": [ { "name": "SEZ6", "type": "recommended", "evidence": [ { "id": "A0A8V1APT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ] } ], "protein_names": [ { "name": "Seizure related 6 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1APT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0", "locus": { "chromosome": "19", "start_pos": 6395340, "end_pos": 6408417, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029681", "url": "https://www.ensembl.org/id/ENSGALG00010029681" } ] } } ], "crossref": [ { "id": "A0A8V1APT0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1APT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEN6", "url": "https://www.orthodb.org/?gene=A0A8V1AEN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK07", "url": "https://www.orthodb.org/?gene=A0A8V1AK07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALP1", "url": "https://www.orthodb.org/?gene=A0A8V1ALP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANB9", "url": "https://www.orthodb.org/?gene=A0A8V1ANB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APT0", "url": "https://www.orthodb.org/?gene=A0A8V1APT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APT2", "url": "https://www.orthodb.org/?gene=A0A8V1APT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK07", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AAEPRCFNGLERKTGESAEAEGDPTALPTPAEREAEARFVSTAPTLKLLNHHPLLEDLLHEAFLKKDYLAQAPFPPGLPAPHIPPRAPALPRVAFPTAPLTTPAGRSGPWGEPWGVAPGTDPSQPPTGGSGSSPAAPSQAPILGTTGVSGDEEGTTTTSTITTTTVTTLQGPGEPPCNRTLAGPEGWLVSPEPASAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGETLTVESAGGLEPAVLANESFLLRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQAYLLSCPFPARPAFGDVSVSSLHPGGDARFRCTTGYQLQGAHLITCRNATRPFWSAREPQCMAACGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSTGRHFFVELTTDSSGAAAGMALRYEAFEQGHCYEPFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLEQGSTIIECVDPSDPQWNETEPACRAVCSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAGDVLTFYDGDDLTARILGQYTGARGRFKLFASSADVTIQFQSDPGAGVFAYRQGFVIHFSEVPRNDTCPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCERVTTCRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDPPAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGHPSRWSGSPPICKAASYDEFYSNRNLDAVAKAVPSETALEGTNVAIAIFLPVLVLALLIGGVYLYFSKLQGKPALQLPLSGSHPYDHITVESAFDNPTYETGVSTDPHALPARSCTLGTRGRM", "length": 932, "header": "tr|A0A8V1APT0-1|A0A8V1APT0_CHICK Isoform 1 of Seizure related 6 homolog OS=Gallus gallus OX=9031 GN=SEZ6 PE=4 SV=1 CANONICAL=A0A8V1APT0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0/entry#A0A8V1AEN6-1", "sequence": { "sequence": "ALLTALHCSNPPHGFNGLERKTGESAEAEGDPTALPTPAEREAEARFVSTAPTLKLLNHHPLLEDLLHEAFLKKDYLAQAPFPPGLPGPVLVAFPTAPLTTPAGRSGPWGEPWGVAPGTDPSQPPTGGSGSSPAAPSQAPILGTTGVSVGREKGVWGDVRLTQGSPCHPAPCNRTLAGPEGWLVSPEPASAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGETLTVESAGGLEPAVLANESFLLRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQAYLLSCPFPARPAFGDVSVSSLHPGGDARFRCTTGYQLQGAHLITCRNATRPFWSAREPQCMAACGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSTGRHFFVELTTDSSGAAAGMALRYEAFEQGHCYEPFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLEQGSTIIECVDPSDPQWNETEPACRAVCSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAGDVLTFYDGDDLTARILGQYTGARGRFKLFASSADVTIQFQSDPGAGVFAYRQGFVIHFSEVPRNDTCPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCERVTTCRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDPPAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGHPSRWSGSPPICKAASYDEFYSNRNLDAVPSETALEGTNVAIAIFLPVLVLALLIGGVYLYFSKLQGKPALQLPLSGSHPYDHITVESAFDNPTYETGSVFFAGNEGI", "length": 912, "header": "tr|A0A8V1AEN6-1|A0A8V1AEN6_CHICK Computationally mapped isoform of Seizure related 6 homolog OS=Gallus gallus OX=9031 GN=SEZ6 PE=4 SV=1 CANONICAL=A0A8V1APT0-1" }, "locus": { "chromosome": "19", "start_pos": 6402614, "end_pos": 6396344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071801.1", "url": "https://www.ensembl.org/id/ENSGALT00010071801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044491.1", "url": "https://www.ensembl.org/id/ENSGALP00010044491.1" } ] } }, { "isoform_ac": "A0A8V1AK07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0/entry#A0A8V1AK07-1", "sequence": { "sequence": "AAEPRCFNGLERKTGESAEAEGDPTALPTPAEREAEARFVSTAPTLKLLNHHPLLEDLLHEAFLKKDYLAQAPFPPGLPAPHIPPRAPALPRVAFPTAPLTTPAGRSGPWGEPWGVAPGTDPSQPPTGGSGSSPAAPSQAPILGTTGVSGDEEGTTTTSTITTTTVTTLQGPAPCNRTLAGPEGWLVSPEPASAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGETLTVESAGGLEPAVLANESFLLRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQAYLLSCPFPARPAFGDVSVSSLHPGGDARFRCTTGYQLQGAHLITCRNATRPFWSAREPQCMAACGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSTGRHFFVELTTDSSGAAAGMALRYEAFEQGHCYEPFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLEQGSTIIECVDPSDPQWNETEPACRAVCSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAGDVLTFYDGDDLTARILGQYTGARGRFKLFASSADVTIQFQSDPGAGVFAYRQGFVIHFSEVPRNDTCPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCERVTTCRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDPPAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGHPSRWSGSPPICKAASYDEFYSNRNLDAGKPALQLPLSGSHPYDHITVESAFDNPTYETGVSTDPHALPARSCTLGTRGRM", "length": 888, "header": "tr|A0A8V1AK07-1|A0A8V1APT0_CHICK Computationally mapped isoform of Seizure related 6 homolog OS=Gallus gallus OX=9031 GN=SEZ6 PE=4 SV=1 CANONICAL=A0A8V1APT0-1" }, "locus": { "chromosome": "19", "start_pos": 6402708, "end_pos": 6396819, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071798.1", "url": "https://www.ensembl.org/id/ENSGALT00010071798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044488.1", "url": "https://www.ensembl.org/id/ENSGALP00010044488.1" } ] } }, { "isoform_ac": "A0A8V1ALP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0/entry#A0A8V1ALP1-1", "sequence": { "sequence": "HEAFLKKDYLAQAPFPPGLPGPVLPDEALRPDPGPPAPHIPPRAPALPRVAFPTAPLTTPAGRSGPWGEPWGVAPGTDPSQPPTGGSGSSPAAPSQAPILGTTGVSGDEEGTTTTSTITTTTVTTLQGPGERGEGEGGLGRCEANTGVSFMDCTYTISVYPGYGVEIKVQNISLADGETLTVESAGGLEPAVLANESFLLRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQAYLLSCPFPARPAFGDVSVSSLHPGGDARFRCTTGYQLQGAHLITCRNATRPFWSAREPQCMAACGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSTGRHFFVELTTDSSGAAAGMALRYEAFEQGHCYEPFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLEQGSTIIECVDPSDPQWNETEPACRAVCSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAGDVLTFYDGDDLTARILGQYTGARGRFKLFASSADVTIQFQSDPGAGVFAYRQGFVIHFSEVPRNDTCPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCERVTTCRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDPPAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGHPSRWSGSPPICKAAVPSETALEGTNVAIAIFLPVLVLALLIGGVYLYFSKLQGKPALQLPLSGSHPYDHITVESAFDNPTYETGETREYEVSI", "length": 852, "header": "tr|A0A8V1ALP1-1|A0A8V1ALP1_CHICK Computationally mapped isoform of Seizure related 6 homolog OS=Gallus gallus OX=9031 GN=SEZ6 PE=4 SV=1 CANONICAL=A0A8V1APT0-1" }, "locus": { "chromosome": "19", "start_pos": 6401814, "end_pos": 6396331, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071800.1", "url": "https://www.ensembl.org/id/ENSGALT00010071800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044490.1", "url": "https://www.ensembl.org/id/ENSGALP00010044490.1" } ] } }, { "isoform_ac": "A0A8V1ANB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0/entry#A0A8V1ANB9-1", "sequence": { "sequence": "CQRAHPALPEPPIHQPWLLPLSVPRYGVLLPPAGMVLSLWGPSVPMGCPCSPSCMTPFCSTQVGLLQGAHLITCRNATRPFWSAREPQCMAACGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSTGRHFFVELTTDSSGAAAGMALRYEAFEQGHCYEPFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLEQGSTIIECVDPSDPQWNETEPACRAVCSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAGDVLTFYDGDDLTARILGQYTGARGRFKLFASSADVTIQFQSDPGAGVFAYRQGFVIHFSEVPRNDTCPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCERVTTCRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDPPAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGHPSRWSGSPPICKAASYDEFYSNRNLDAVPSETALEGTNVAIAIFLPVLVLALLIGGVYLYFSKLQGKPALQLPLSGSHPYDHITVESAFDNPTYETGETREYEVSI", "length": 661, "header": "tr|A0A8V1ANB9-1|A0A8V1ANB9_CHICK Computationally mapped isoform of Seizure related 6 homolog OS=Gallus gallus OX=9031 GN=SEZ6 PE=4 SV=1 CANONICAL=A0A8V1APT0-1" }, "locus": { "chromosome": "19", "start_pos": 6400509, "end_pos": 6396331, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071794.1", "url": "https://www.ensembl.org/id/ENSGALT00010071794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044484.1", "url": "https://www.ensembl.org/id/ENSGALP00010044484.1" } ] } }, { "isoform_ac": "A0A8V1APT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0/entry#A0A8V1APT0-1", "sequence": { "sequence": "AAEPRCFNGLERKTGESAEAEGDPTALPTPAEREAEARFVSTAPTLKLLNHHPLLEDLLHEAFLKKDYLAQAPFPPGLPAPHIPPRAPALPRVAFPTAPLTTPAGRSGPWGEPWGVAPGTDPSQPPTGGSGSSPAAPSQAPILGTTGVSGDEEGTTTTSTITTTTVTTLQGPGEPPCNRTLAGPEGWLVSPEPASAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGETLTVESAGGLEPAVLANESFLLRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQAYLLSCPFPARPAFGDVSVSSLHPGGDARFRCTTGYQLQGAHLITCRNATRPFWSAREPQCMAACGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSTGRHFFVELTTDSSGAAAGMALRYEAFEQGHCYEPFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLEQGSTIIECVDPSDPQWNETEPACRAVCSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAGDVLTFYDGDDLTARILGQYTGARGRFKLFASSADVTIQFQSDPGAGVFAYRQGFVIHFSEVPRNDTCPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCERVTTCRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDPPAYEPCHNPGVPAGGRQSPERRLYPAGSTLRFSCTAGRALLGEGNLRCLPGHPSRWSGSPPICKAASYDEFYSNRNLDAVAKAVPSETALEGTNVAIAIFLPVLVLALLIGGVYLYFSKLQGKPALQLPLSGSHPYDHITVESAFDNPTYETGVSTDPHALPARSCTLGTRGRM", "length": 932, "header": "tr|A0A8V1APT0-1|A0A8V1APT0_CHICK Isoform 1 of Seizure related 6 homolog OS=Gallus gallus OX=9031 GN=SEZ6 PE=4 SV=1 CANONICAL=A0A8V1APT0-1" }, "locus": { "chromosome": "19", "start_pos": 6402708, "end_pos": 6396819, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071797.1", "url": "https://www.ensembl.org/id/ENSGALT00010071797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044487.1", "url": "https://www.ensembl.org/id/ENSGALP00010044487.1" } ] } }, { "isoform_ac": "A0A8V1APT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0/entry#A0A8V1APT2-1", "sequence": { "sequence": "MGSAPPPALLLPLLAALLRAPAHGFNGLERKTGESAEAEGDPTALPTPAEREAEARFVSTAPTLKLLNHHPLLEDLLHEAFLKKDYLAQAPFPPGLPGPVLPDEALRPDPGPPAPHIPPRAPALPRVAFPTAPLTTPAGRSGPWGEPWGVAPGTDPSQPPTGGSGSSPAAPSQAPILGTTGVSGDEEGTTTTSTITTTTVTTLQGPAPCNRTLAGPEGWLVSPEPASAPYDSSMDCTYTISVYPGYGVEIKVQNISLADGETLTVESAGGLEPAVLANESFLLRGQVIRSPANVLTLRFQSPRSTSPGSYRFQYQAYLLSCPFPARPAFGDVSVSSLHPGGDARFRCTTGYQLQGAHLITCRNATRPFWSAREPQCMAACGGAIRNATVGRVVSPGFPGNYSNNLTCHWLLEAPVGHRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSTGRHFFVELTTDSSGAAAGMALRYEAFEQGHCYEPFVKYGNFTTSDPRYPVGTTVEFSCHPGYTLEQGSTIIECVDPSDPQWNETEPACRAVCSGELMDTAGVVLSPNWPEAYGKGQDCIWGLHVEEDKRVMLDIRVLRLGAGDVLTFYDGDDLTARILGQYTGARGRFKLFASSADVTIQFQSDPGAGVFAYRQGFVIHFSEVPRNDTCPELPDIANGWKTASQPELLHGTVVTFHCYPGFELAGADLLMCHWDLTWSGDLPSCERVTTCRDPGDAEHSRRVVSSPKFPVGSTVRFVCDKGYVLAGAGLLTCHDRASGGPKWSDPPAQMHPGGVRAMPQPRRARGRAAEPRAAAVPGGEHAALLLHRWAGAAG", "length": 838, "header": "tr|A0A8V1APT2-1|A0A8V1APT2_CHICK Computationally mapped isoform of Seizure related 6 homolog OS=Gallus gallus OX=9031 GN=SEZ6 PE=4 SV=1 CANONICAL=A0A8V1APT0-1" }, "locus": { "chromosome": "19", "start_pos": 6408354, "end_pos": 6397471, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071802.1", "url": "https://www.ensembl.org/id/ENSGALT00010071802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044492.1", "url": "https://www.ensembl.org/id/ENSGALP00010044492.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" }, { "name": "apical dendrite", "id": "GO:0097440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097440", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synapse maturation", "id": "GO:0060074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" }, { "name": "regulation of dendrite development", "id": "GO:0050773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 285, "start_aa": "Cys", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1APT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APT0" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 287, "end_pos": 346, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 29 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 639, "end_pos": 641 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANE2-1", "uniprot_ac": "A0A8V1ANE2", "uniprot_id": "A0A8V1ANE2_CHICK", "mass": { "chemical_mass": 85515.0, "monoisotopic_mass": 85515.0 }, "refseq": { "ac": "XP_015151256", "name": "ARF GTPase-activating protein GIT1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151256" }, "gene_names": [ { "name": "GIT1", "type": "recommended", "evidence": [ { "id": "A0A8V1ANE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ] }, { "name": "GIT1", "type": "synonym", "evidence": [ { "id": "XP_015151256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151256" } ] }, { "name": "p95-APP1", "type": "synonym", "evidence": [ { "id": "XP_015151256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151256" } ] } ], "protein_names": [ { "name": "ARF GTPase-activating protein GIT1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151256" } ] }, { "name": "G protein-coupled receptor kinase interacting ArfGAP 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ANE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151256.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151256" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GIT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2", "locus": { "chromosome": "19", "start_pos": 6546911, "end_pos": 6554819, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029697", "url": "https://www.ensembl.org/id/ENSGALG00010029697" } ] } } ], "crossref": [ { "id": "A0A8V1ANE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08846", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08846", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417584", "url": "https://www.ncbi.nlm.nih.gov/gene/417584", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417584", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417584", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IDHKNGH", "url": "https://omabrowser.org/oma/group/IDHKNGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AER5", "url": "https://www.orthodb.org/?gene=A0A8V1AER5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK39", "url": "https://www.orthodb.org/?gene=A0A8V1AK39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANE2", "url": "https://www.orthodb.org/?gene=A0A8V1ANE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APU6", "url": "https://www.orthodb.org/?gene=A0A8V1APU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46097", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46097", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46097:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46097:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08518", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08518", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3928664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151256", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AER5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AER5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRKAQRAEVCADCSAADPGWASINRGVLICDECCSVHRSLGRHISIVKHLRHSPWPATLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPTKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQILQAELLVVYGADPGAPDVNGRTPIDYARQAAQHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADRVRPKCMAQSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLLIDILGEAKRRQQGKSPLSPTDALDYSLRSQSDLDDQHDYDSVASDEDTDQELLRNASRNNRARSMDSSDLSDGPITLQEYLEVKKALAASEAKVQQLMKVNNSLSDELRRLQREIHKLQSENTQIRQQAVPPHPTPAPSERPEHGHPPGTAPLHRRDRQAFSMYEPGSVLKPFGQPVEELVTRLQPFGGGEVEDEALYSMHIPASVYRMRKGPSVSSMPFPPSSPLLSCPPDGARHMSKLDRHGSGTDSDYDNTQTGEILLGMEGKRFVELSKDEDFPHELDPLDGELDPGLPSTEDVILKTEQVTKNIQELLRAAQESKHDSFVPCSEKIHSAVTEMASLFPKKPALETVRSSLRLLNASAYRLQSECRKTVPPEPGAAVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 767, "header": "tr|A0A8V1ANE2-1|A0A8V1ANE2_CHICK Isoform 1 of G protein-coupled receptor kinase interacting ArfGAP 1 OS=Gallus gallus OX=9031 GN=GIT1 PE=1 SV=1 CANONICAL=A0A8V1ANE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AER5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2/entry#A0A8V1AER5-1", "sequence": { "sequence": "MSRKAQRAEVCADCSAADPGWASINRGVLICDECCSVHRSLGRHISIVKHLRHSPWPATLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPTKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQILQAELLVVYGADPGAPDVNGRTPIDYARQAAQHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLLIDILGEAKRRQQGKSPLSPTDALDYSLRSQSDLDDQHDYDSVASDEDTDQELLRNASRNNRARSMDSSDLSDGPITLQEYLEVKKALAASEAKVQQLMKVNNSLSDELRRLQREIHKLQSENTQIRQQAVPPHPTPAPSERPEHGHPPGTAPLHRRDRQAFSMYEPGSVLKPFGQPVEELVTRLQPFGGGMRKGPSVSSMPFPPSSPLLSCPPDGARHMSKLDRHGSGTDSDYDNTQTGEILLGMEGKRFVELSKDEDFPHELDPLDGELDPGLPSTEDVILKTEQVTKNIQELLRAAQESKHDSFVPCSEKIHSAVTEMASLFPKKPALETVRSSLRLLNASAYRLQSECRKTVPPEPGAAVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 740, "header": "tr|A0A8V1AER5-1|A0A8V1AER5_CHICK Computationally mapped isoform of G protein-coupled receptor kinase interacting ArfGAP 1 OS=Gallus gallus OX=9031 GN=GIT1 PE=1 SV=1 CANONICAL=A0A8V1ANE2-1" }, "locus": { "chromosome": "19", "start_pos": 6554637, "end_pos": 6547272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071832.1", "url": "https://www.ensembl.org/id/ENSGALT00010071832.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044522.1", "url": "https://www.ensembl.org/id/ENSGALP00010044522.1" } ] } }, { "isoform_ac": "A0A8V1AK39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2/entry#A0A8V1AK39-1", "sequence": { "sequence": "MSRKAQRAEVCADCSAADPGWASINRGVLICDECCSVHRSLGRHISIVKHLRHSPWPATLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPTKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQILQAELLVVYGADPGAPDVNGRTPIDYARQAAQHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLLIDILGEAKRRQQGKSPLSPTDALDYSLRSQSDLDDQHDYDSVASDEDTDQELLRNASRNNRARSMDSSDLSDGPITLQEYLEVKKALAASEAKVQQLMKVNNSLSDELRRLQREIHKLQSENTQIRQQAVPPHPTPAPSERPEHGHPPGTAPLHRRDRQAFSMYEPGSVLKPFGQPVEELVTRLQPFGGGEVEDEALYSMHIPASVYRSKLDRHGSGTDSDYDNTQTGEILLGMEGKRFVELSKDEDFPHELDPLDGELDPGLPSTEDVILKTEQVTKNIQELLRAAQESKHDSFVPCSEKIHSAVTEMASLFPKKPALETVRSSLRLLNASAYRLQSECRKTVPPEPGAAVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 729, "header": "tr|A0A8V1AK39-1|A0A8V1ANE2_CHICK Computationally mapped isoform of G protein-coupled receptor kinase interacting ArfGAP 1 OS=Gallus gallus OX=9031 GN=GIT1 PE=1 SV=1 CANONICAL=A0A8V1ANE2-1" }, "locus": { "chromosome": "19", "start_pos": 6554637, "end_pos": 6547272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071829.1", "url": "https://www.ensembl.org/id/ENSGALT00010071829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044519.1", "url": "https://www.ensembl.org/id/ENSGALP00010044519.1" } ] } }, { "isoform_ac": "A0A8V1ANE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2/entry#A0A8V1ANE2-1", "sequence": { "sequence": "MSRKAQRAEVCADCSAADPGWASINRGVLICDECCSVHRSLGRHISIVKHLRHSPWPATLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPTKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQILQAELLVVYGADPGAPDVNGRTPIDYARQAAQHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADRVRPKCMAQSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLLIDILGEAKRRQQGKSPLSPTDALDYSLRSQSDLDDQHDYDSVASDEDTDQELLRNASRNNRARSMDSSDLSDGPITLQEYLEVKKALAASEAKVQQLMKVNNSLSDELRRLQREIHKLQSENTQIRQQAVPPHPTPAPSERPEHGHPPGTAPLHRRDRQAFSMYEPGSVLKPFGQPVEELVTRLQPFGGGEVEDEALYSMHIPASVYRMRKGPSVSSMPFPPSSPLLSCPPDGARHMSKLDRHGSGTDSDYDNTQTGEILLGMEGKRFVELSKDEDFPHELDPLDGELDPGLPSTEDVILKTEQVTKNIQELLRAAQESKHDSFVPCSEKIHSAVTEMASLFPKKPALETVRSSLRLLNASAYRLQSECRKTVPPEPGAAVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 767, "header": "tr|A0A8V1ANE2-1|A0A8V1ANE2_CHICK Isoform 1 of G protein-coupled receptor kinase interacting ArfGAP 1 OS=Gallus gallus OX=9031 GN=GIT1 PE=1 SV=1 CANONICAL=A0A8V1ANE2-1" }, "locus": { "chromosome": "19", "start_pos": 6554637, "end_pos": 6547272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071830.1", "url": "https://www.ensembl.org/id/ENSGALT00010071830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044520.1", "url": "https://www.ensembl.org/id/ENSGALP00010044520.1" } ] } }, { "isoform_ac": "A0A8V1APU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2/entry#A0A8V1APU6-1", "sequence": { "sequence": "MECVCVGVCVCVCMCVCVCAGGGHAHGLMSSFILFFPPLLPPERRVRPKCMAQRYCPLGAHTGAPPVPPGWALGAQHSPLGGSWEGWGGWGGSRSPHATPTPWTPPRAWQSPRAWGTQGTSGEPFGRGGTGITPTLCPPHLMHPTAWTCPSWPRRPRRSCKRSATACLRSWPWMCTTRWIGARTTRVSGAGGGCWVSPPPGWVLAAVPAQGGAEPGAPPDPIRTAPQAPPSSFLGPGPGAVSFREGLRCRIGVPGGGVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLLIDILGEAKRRQQGKSPLSPTDALDYSLRSQSDLDDQHDYDSVASDEDTDQELLRNASRNNRARSMDSSDLSDGPITLQEYLEVKKALAASEAKVQQLMKVNNSLSDELRRLQREIHKLQSENTQIRQQAVPPHPTPAPSERPEHGHPPGTAPLHRRDRQAFSMYEPGSVLKPFGQPVEELVTRLQPFGGGEVEDEALYSMHIPASVYRMRKGPSVSSMPFPPSSPLLSCPPDGARHMSKLDRHGSGTDSDYDNTQTGEILLGMEGKRFVELSKDEDFPHELDPLDGELDPGLPSTEDVILKTEQVTKNIQELLRAAQESKHDSFVPCSEKIHSAVTEMASLFPKKPALETVRSSLRLLNASAYRLQSECRKTVPPEPGAAVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 721, "header": "tr|A0A8V1APU6-1|A0A8V1APU6_CHICK Computationally mapped isoform of G protein-coupled receptor kinase interacting ArfGAP 1 OS=Gallus gallus OX=9031 GN=GIT1 PE=1 SV=1 CANONICAL=A0A8V1ANE2-1" }, "locus": { "chromosome": "19", "start_pos": 6550946, "end_pos": 6547272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071828.1", "url": "https://www.ensembl.org/id/ENSGALT00010071828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044518.1", "url": "https://www.ensembl.org/id/ENSGALP00010044518.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 488, "start_aa": "Thr", "end_pos": 488, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr488", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417584", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417584", "resource": "KEGG Pathway" }, { "id": "R-GGA-3928664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928664", "resource": "Reactome", "description": "Ephrin signaling" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-GGA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M7Q3-1", "protein_name": "GIT ArfGAP 1", "gene_name": "GIT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADRSRQKCMSQSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLGSPTDNLELSTRGQSDLDDQHDYDSVASDEDTDQEPLRSAGATRNNRARSMDSSDLSDGAVTLQEYLELKKALAASEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQIRQPPGPMPTPPLPSERAEHAPVGPGGSTHRRDRQAFSMYEPGSALKPFGVPPGDELTTRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSRHTSKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRSSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 770 }, "evidence": [ { "id": "A0A8V1ANE2", "url": "https://omabrowser.org/oma/group/A0A8V1ANE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q68FF6-1", "protein_name": "ARF GTPase-activating protein GIT1", "gene_name": "Git1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADRSRQKCMSQSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSARSQSELDDQHDYDSVASDEDTDQEPLPSAGATRNNRARSMDSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQLRQPPGPVPPPSLPSERAEHTLMGPGGSTHRRDRQAFSMYEPGSALKPFGGTPGDELATRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASSVPFTPSSPLLSCSQEGSRHASKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELSKEDELHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRSSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 770 }, "evidence": [ { "id": "A0A8V1ANE2", "url": "https://omabrowser.org/oma/group/A0A8V1ANE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2X7-1", "protein_name": "ARF GTPase-activating protein GIT1", "gene_name": "GIT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSLRSQSDLDDQHDYDSVASDEDTDQEPLRSTGATRSNRARSMDSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQLRQPPGPVPTPPLPSERAEHTPMAPGGSTHRRDRQAFSMYEPGSALKPFGGPPGDELTTRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSRHTSKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRSSLRLLNASAYRLQSECRKTVPPEPGAPVDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "length": 761 }, "evidence": [ { "id": "A0A8V1ANE2", "url": "https://omabrowser.org/oma/group/A0A8V1ANE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "negative regulation of interleukin-1 beta production", "id": "GO:0032691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "motor learning", "id": "GO:0061743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "negative regulation of glycolytic process", "id": "GO:0045820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045820", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "cell redox homeostasis", "id": "GO:0045454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045454", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "neuron development", "id": "GO:0048666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "synaptic vesicle recycling", "id": "GO:0036465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "intramembranous ossification", "id": "GO:0001957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001957", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "positive regulation of microtubule nucleation", "id": "GO:0090063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response to wounding", "id": "GO:0106015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE2" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 124, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 488 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 310, "end_pos": 312 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 712, "end_pos": 714 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1APV1-1", "uniprot_ac": "A0A8V1APV1", "uniprot_id": "A0A8V1APV1_CHICK", "mass": { "chemical_mass": 57544.0, "monoisotopic_mass": 57544.0 }, "refseq": { "ac": "XP_015151583", "name": "coronin-6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151583" }, "gene_names": [ { "name": "CORO6", "type": "recommended", "evidence": [ { "id": "A0A8V1APV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1" } ] }, { "name": "CORO6", "type": "synonym", "evidence": [ { "id": "XP_015151583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151583" } ] } ], "protein_names": [ { "name": "Coronin", "type": "recommended", "evidence": [ { "id": "A0A8V1APV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1/entry#names_and_taxonomy" } ] }, { "name": "coronin-6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151583" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015151583.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CORO6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1", "locus": { "chromosome": "19", "start_pos": 6563520, "end_pos": 6569473, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029702", "url": "https://www.ensembl.org/id/ENSGALG00010029702" } ] } } ], "crossref": [ { "id": "A0A8V1APV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1APV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857679", "url": "https://www.ncbi.nlm.nih.gov/gene/100857679", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857679", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857679", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPPILMH", "url": "https://omabrowser.org/oma/group/YPPILMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AK47", "url": "https://www.orthodb.org/?gene=A0A8V1AK47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALS5", "url": "https://www.orthodb.org/?gene=A0A8V1ALS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANE7", "url": "https://www.orthodb.org/?gene=A0A8V1ANE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APV1", "url": "https://www.orthodb.org/?gene=A0A8V1APV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AK47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AK47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AK47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRVVRQSKFRHVFGQPVKADQMYEDIRVSKVTWDSSFCAVNPKFLAIIVESGGGGAFMVLPLAKTGRVDKNHPLVTGHTAPVLDIDWCPHNDNVIASASEDTTVMVWQIPDYVPVRSITEPVVTLEGHSKRVGIICWHPTARNVLLSAGCDNLVILWNVGTGEMLLALEDMHTDLIYNVGWNRNGSLLVTTCKDKKVRVIDPRKQTVVAEITKPHDGARPIRAIFMADGKIFTTGFSKMSERQLGLWDLERFAPHEGLRPVRAIFTREGHIFTTGFTRMSQRELGLWDPKNFEEPIALQEMDTSNGVLLPFYDADSSIVYLCGKGDSSIRYFEITDEAPYVHYLNTYSSKEPQRGMGFMPKRGLDVSKCEIARFFKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGKDAEPILISLRDGYVPVKNRELKVVKKNILDSKPPPGPRRSHSTSNTDISTPALDEVLEEIRVLKETVQAQEKRISALEHKLCQFTNGTD", "length": 511, "header": "tr|A0A8V1APV1-1|A0A8V1APV1_CHICK Isoform 1 of Coronin OS=Gallus gallus OX=9031 GN=CORO6 PE=3 SV=1 CANONICAL=A0A8V1APV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AK47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1/entry#A0A8V1AK47-1", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQPVKADQMYEDIRVSKVTWDSSFCAVNPKFLAIIVESGGGGAFMVLPLAKTGRVDKNHPLVTGHTAPVLDIDWCPHNDNVIASASEDTTVMVWQIPDYVPVRSITEPVVTLEGHSKRVGIICWHPTARNVLLSAGCDNLVILWNVGTGEMLLALEDMHTDLIYNVGWNRNGSLLVTTCKDKKVRVIDPRKQTVVAERFAPHEGLRPVRAIFTREGHIFTTGFTRMSQRELGLWDPKNFEEPIALQEMDTSNGVLLPFYDADSSIVYLCGKGDSSIRYFEITDEAPYVHYLNTYSSKEPQRGMGFMPKRGLDVSKCEIARFFKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGKDAEPILISLRDGYVPVKNRELKVVKKNILDSKPPPGPRRSHSTSNTDISTPALDEVLEEIRVLKETVQAQEKRISALEHKLCQFTNGTD", "length": 471, "header": "tr|A0A8V1AK47-1|A0A8V1APV1_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO6 PE=3 SV=1 CANONICAL=A0A8V1APV1-1" }, "locus": { "chromosome": "19", "start_pos": 6567834, "end_pos": 6563949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071840.1", "url": "https://www.ensembl.org/id/ENSGALT00010071840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044530.1", "url": "https://www.ensembl.org/id/ENSGALP00010044530.1" } ] } }, { "isoform_ac": "A0A8V1ALS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1/entry#A0A8V1ALS5-1", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQPVKADQMYEDIRVSKVTWDSSFCAVNPKFLAIIVESGGGGAFMVLPLAKTGRVDKNHPLVTGHTAPVLDIDWCPHNDNVIASASEDTTVMVWQIPDYVPVRSITEPVVTLEGHSKRVGIICWHPTARNVLLSAGCDNLVILWNVGTGEMLLALEDMHTDLIYNVGWNRNGSLLVTTCKDKKVRVIDPRKQTVVAKNFEEPIALQEMDTSNGVLLPFYDADSSIVYLCGKGDSSIRYFEITDEAPYVHYLNTYSSKEPQRGMGFMPKRGLDVSKCEIARFFKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGKDAEPILISLRDGYVPVKNRELKVVKKNILDSKPPPGPRRSHSTSNTDISTPALDEVLEEIRVLKETVQAQEKRISALEHKLCQFTNGTD", "length": 431, "header": "tr|A0A8V1ALS5-1|A0A8V1ALS5_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO6 PE=3 SV=1 CANONICAL=A0A8V1APV1-1" }, "locus": { "chromosome": "19", "start_pos": 6567834, "end_pos": 6563949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071842.1", "url": "https://www.ensembl.org/id/ENSGALT00010071842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044532.1", "url": "https://www.ensembl.org/id/ENSGALP00010044532.1" } ] } }, { "isoform_ac": "A0A8V1ANE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1/entry#A0A8V1ANE7-1", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQPVKADQMYEDIRVSKVTWDSSFCAVNPKFLAIIVESGGGGAFMVLPLAKTGRVDKNHPLVTGHTAPVLDIDWCPHNDNVIASASEDTTVMVWQIPDYVPVRSITEPVVTLEGHSKRVGIICWHPTARNVLLSAGCDNLVILWNVGTGEMLLALEDMHTDLIYNVGWNRNGSLLVTTCKDKKVRVIDPRKQTVVAEITKPHDGARPIRAIFMADGKIFTTGFSKMSERQLGLWDLKNFEEPIALQEMDTSNGVLLPFYDADSSIVYLCGKGDSSIRYFEITDEAPYVHYLNTYSSKEPQRGMGFMPKRGLDVSKCEIARFFKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGKDAEPILISLRDGYVPVKNRELKVVKKNILDSKPPPGPRRSHSTSNTDISTPALDEVLEEIRVLKETVQAQEKRISALEHKLCQFTNGTD", "length": 471, "header": "tr|A0A8V1ANE7-1|A0A8V1ANE7_CHICK Computationally mapped isoform of Coronin OS=Gallus gallus OX=9031 GN=CORO6 PE=3 SV=1 CANONICAL=A0A8V1APV1-1" }, "locus": { "chromosome": "19", "start_pos": 6567834, "end_pos": 6563949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071841.1", "url": "https://www.ensembl.org/id/ENSGALT00010071841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044531.1", "url": "https://www.ensembl.org/id/ENSGALP00010044531.1" } ] } }, { "isoform_ac": "A0A8V1APV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1/entry#A0A8V1APV1-1", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQPVKADQMYEDIRVSKVTWDSSFCAVNPKFLAIIVESGGGGAFMVLPLAKTGRVDKNHPLVTGHTAPVLDIDWCPHNDNVIASASEDTTVMVWQIPDYVPVRSITEPVVTLEGHSKRVGIICWHPTARNVLLSAGCDNLVILWNVGTGEMLLALEDMHTDLIYNVGWNRNGSLLVTTCKDKKVRVIDPRKQTVVAEITKPHDGARPIRAIFMADGKIFTTGFSKMSERQLGLWDLERFAPHEGLRPVRAIFTREGHIFTTGFTRMSQRELGLWDPKNFEEPIALQEMDTSNGVLLPFYDADSSIVYLCGKGDSSIRYFEITDEAPYVHYLNTYSSKEPQRGMGFMPKRGLDVSKCEIARFFKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGKDAEPILISLRDGYVPVKNRELKVVKKNILDSKPPPGPRRSHSTSNTDISTPALDEVLEEIRVLKETVQAQEKRISALEHKLCQFTNGTD", "length": 511, "header": "tr|A0A8V1APV1-1|A0A8V1APV1_CHICK Isoform 1 of Coronin OS=Gallus gallus OX=9031 GN=CORO6 PE=3 SV=1 CANONICAL=A0A8V1APV1-1" }, "locus": { "chromosome": "19", "start_pos": 6567834, "end_pos": 6563949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071839.1", "url": "https://www.ensembl.org/id/ENSGALT00010071839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044529.1", "url": "https://www.ensembl.org/id/ENSGALP00010044529.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857679", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857679", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F6RCR6-1", "protein_name": "Coronin", "gene_name": "CORO6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPVRSITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNTNGSLLATTCKDKTLRIIDPRKGQVVAERFAAHEGMRPMRAVFTRQGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDADPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASNAPLSQHTLETLLEEIKALREQVQAQEQRITSLENMLCELVDGTD", "length": 471 }, "evidence": [ { "id": "A0A8V1APV1", "url": "https://omabrowser.org/oma/group/A0A8V1APV1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6QEF8-1", "protein_name": "Coronin-6", "gene_name": "CORO6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAEQARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD", "length": 472 }, "evidence": [ { "id": "A0A8V1APV1", "url": "https://omabrowser.org/oma/group/A0A8V1APV1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920J3-1", "protein_name": "Coronin-6", "gene_name": "Coro6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERFAAHEGMRPMRAVFTRLGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHREFRVTKRNILDVRPPASPRRSQSASEAPLSQQHTLETLLEEMKALRERVQAQEERITALENMLCELVDGTD", "length": 472 }, "evidence": [ { "id": "A0A8V1APV1", "url": "https://omabrowser.org/oma/group/A0A8V1APV1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920M5-1", "protein_name": "Coronin-6", "gene_name": "Coro6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHRELRVTKRNILDVRPPASPRRSQSASEAPLSQHTLETLLEEIKALRDRVQAQEERITALENMLCELVDGTD", "length": 471 }, "evidence": [ { "id": "A0A8V1APV1", "url": "https://omabrowser.org/oma/group/A0A8V1APV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "actin filament", "id": "GO:0005884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005884", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APV1" }, { "id": "SM01166", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1899", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 68, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 508, "end_pos": 510 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALX1-1", "uniprot_ac": "A0A8V1ALX1", "uniprot_id": "A0A8V1ALX1_CHICK", "mass": { "chemical_mass": 116786.0, "monoisotopic_mass": 116786.0 }, "refseq": { "ac": "XP_015151315", "name": "cytospin-B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151315" }, "gene_names": [ { "name": "SPECC1", "type": "recommended", "evidence": [ { "id": "A0A8V1ALX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ] }, { "name": "SPECC1", "type": "synonym", "evidence": [ { "id": "XP_015151315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151315" } ] } ], "protein_names": [ { "name": "Sperm antigen with calponin homology and coiled-coil domains 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ALX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1/entry#names_and_taxonomy" } ] }, { "name": "cytospin-B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151315" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151315" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPECC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1", "locus": { "chromosome": "19", "start_pos": 6913454, "end_pos": 6840548, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029722", "url": "https://www.ensembl.org/id/ENSGALG00010029722" } ] } } ], "crossref": [ { "id": "A0A8V1ALX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004400", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004400", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417595", "url": "https://www.ncbi.nlm.nih.gov/gene/417595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LISELEX", "url": "https://omabrowser.org/oma/group/LISELEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AEX3", "url": "https://www.orthodb.org/?gene=A0A8V1AEX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKA3", "url": "https://www.orthodb.org/?gene=A0A8V1AKA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALX1", "url": "https://www.orthodb.org/?gene=A0A8V1ALX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANI2", "url": "https://www.orthodb.org/?gene=A0A8V1ANI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVU7", "url": "https://www.orthodb.org/?gene=E1BVU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43941:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43941:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151315", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AEX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVU7", "url": "https://www.uniprot.org/uniprotkb/E1BVU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVU7-1", "url": "https://www.uniprot.org/uniprotkb/E1BVU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSTARPWSAVSKQGSHGVDRGKSLSTASSGMKTSKSSTSLAFESRLSKLKRACSDDMLTKPGVTAASGVSRLKKTITTGAISELAESRLKPSTGTVSTAKRTGIPAPREISSSVSRERAVLRGQANTRKTQPSPTSSGTPTPTKHVRPTSKSKQESETGDKAVLESQVKELLAEAKTKDSEITKLRCELKKCKEKGSLNPEGMGASDQNVETLSPVDIDPLIRTLQEKNRTFQKELASLGEENRVLKEKLLYLENSPLSDTTTSSGGDSSLPTPTTQESSFGSPSKNVLRGETVEHRQRVNGGTLRNSASSSSDVTKASLSPDASDFEHIADIPSRPASSNSNHFKGSKCSTTGSSPNNISDLSVASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVEEKALLETSFRQHRDRAEQLGQENEKLMTLLQERSKSEESRAQEGKVLELEQKCAEVLEKAQFEREKLLNIQQQLTSSLRSLEREHQDAQQVIKGLRDENEKLLKLLEVEQQSNSTVTKTLEDCKIALEGLKIENGSLKTQLESEKQKAAEINAMGCTTDNSEVQELLKVAHAEKDQLEASCTELKQELLKANSELKHVQGLLSKAENECGQLKEVCERQAEQLSRTSQKLQEKTSENEADIKNLKETIFELEDQVEQHRAIKLHNNQIISDLESKTMKLEEQKQDIERQLKALTKQMKEDTEEWKRFQADLQTAVVVANDIKCEAQQELRVVKRKLQEEEEKSARLQKELDEVKGNNRLTAEEVESIETDTANRWQGVCISRASPTPSESAATVKSLIKSFDLGCSGSTGQNITVQKVPRSPLSGIPVRTAPAAAVSPMQRHSVYNNTKPASKGVVKHTDLSDLPLADLLKGRNEELKPDHYLRKSPSLESLSKPPMAFSSRMLNSTPSSLKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQDKKRNLLLAFQAAESVGIKPSLELSEMMYTDRPDWQSVMQYVAQIYKYFET", "length": 1053, "header": "tr|A0A8V1ALX1-1|A0A8V1ALX1_CHICK Isoform 1 of Sperm antigen with calponin homology and coiled-coil domains 1 OS=Gallus gallus OX=9031 GN=SPECC1 PE=1 SV=1 CANONICAL=A0A8V1ALX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1/entry#A0A8V1AEX3-1", "sequence": { "sequence": "MGNQPGRVEEHDQGTVSTAKRTGIPAPREISSSVSRERAVLRGQANTRKTQPSPTSSGTPTPTKHVRPTSKSKQESETGDKAVLESQVKELLAEAKTKDSEITKLRCELKKCKEKGSLNPEGMGASDQNVETLSPVDIDPLIRTLQEKNRTFQKELASLGEENRVLKEKLLYLENSPLSDTTTSSGGDSSLPTPTTQESSFGSPSKNVLRGETVEHRQRVNGGTLRNSASSSSDVTKASLSPDASDFEHIADIPSRPASSNSNHFKGSKCSTTGSSPNNISDLSVASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVEEKALLETSFRQHRDRAEQLGQENEKLMTLLQERSKSEESRAQEGKVLELEQKCAEVLEKAQFEREKLLNIQQQLTSSLRSLEREHQDAQQVIKGLRDENEKLLKLLEVEQQSNSTVTKTLEDCKIALEGLKIENGSLKTQLESEKQKAAEINAMGCTTDNSEVQELLKVAHAEKDQLEASCTELKQELLKANSELKHVQGLLSKAENECGQLKEVCERQAEQLSRTSQKLQEKTSENEADIKNLKETIFELEDQVEQHRAIKLHNNQIISDLESKTMKLEEQKQDIERQLKALTKQMKEDTEEWKRFQADLQTAVVVANDIKCEAQQELRVVKRKLQEEEEKSARLQKELDEVKGNNRLTAEEVESIETDTANRWQGVCISRASPTPSESAATVKSLIKSFDLGCSGSTGQNITVQKVPRSPLSGIPVRTAPAAAVSPMQRHSVYNNTKPASKGVVKHTDLSDLPLADLLKGRNEELKPDHYLRKSPSLESLSKPPMAFSSRMLNSTPSSLKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTEGYQFNRILQSEF", "length": 893, "header": "tr|A0A8V1AEX3-1|A0A8V1AEX3_CHICK Computationally mapped isoform of Sperm antigen with calponin homology and coiled-coil domains 1 OS=Gallus gallus OX=9031 GN=SPECC1 PE=1 SV=1 CANONICAL=A0A8V1ALX1-1" }, "locus": { "chromosome": "19", "start_pos": 6896477, "end_pos": 6861152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071893.1", "url": "https://www.ensembl.org/id/ENSGALT00010071893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044583.1", "url": "https://www.ensembl.org/id/ENSGALP00010044583.1" } ] } }, { "isoform_ac": "A0A8V1AKA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1/entry#A0A8V1AKA3-1", "sequence": { "sequence": "MGNQPGRVEEHDQGTVSTAKRTGIPAPREISSSVSRERAVLRGQANTRKTQPSPTSSGTPTPTKHVRPTSKSKQESETGDKAVLESQVKELLAEAKTKDSEITKLRCELKKCKEKGSLNPEGMGASDQNVETLSPVDIDPLIRTLQEKNRTFQKELASLGEENRVLKEKLLYLENSPLSDTTTSSGGDSSLPTPTTQESSFGSPSKNVLRGETVEHRQRVNGGTLRNSASSSSDVTKASLSPDASDFEHIADIPSRPASSNSNHFKGSKCSTTGSSPNNISDLSVASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVEEKALLETSFRQHRDRAEQLGQENEKLMTLLQERSKSEESRAQEGKVLELEQKCAEVLEKAQFEREKLLNIQQQLTSSLRSLEREHQDAQQVIKGLRDENEKLLKLLEVEQQSNSTVTKTLEDCKIALEGLKIENGSLKTQLESEKQKAAEINAMGCTTDNSEVQELLKVAHAEKDQLEASCTELKQELLKANSELKHVQGLLSKAENECGQLKEVCERQAEQLSRTSQKLQEKTSENEADIKNLKETIFELEDQVEQHRAIKLHNNQIISDLESKTMKLEEQKQDIERQLKALTKQMKEDTEEWKRFQADLQTAVVVANDIKCEAQQELRVVKRKLQEEEEKSARLQKELDEVKGNNRLTAEEVESIETDTANRWQGVCISRASPTPSESAATVKSLIKSFDLGCSGSTGQNITVQKVPRSPLSGIPVRTAPAAAVSPMQRHSVYNNTKPASKGVVKHTDLSDLPLADLLKGRNEELKPDHYLRKSPSLESLSKPPMAFSSRMLNSTPSSLKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQDKKRNLLLAFQAAESVGIKPSLVSNLLLAREELLPTSLQSLCCHVAGQPACTENAHSVLGKAAPPSLKVHVVLRSPSSPNL", "length": 1002, "header": "tr|A0A8V1AKA3-1|A0A8V1ALX1_CHICK Computationally mapped isoform of Sperm antigen with calponin homology and coiled-coil domains 1 OS=Gallus gallus OX=9031 GN=SPECC1 PE=1 SV=1 CANONICAL=A0A8V1ALX1-1" }, "locus": { "chromosome": "19", "start_pos": 6909340, "end_pos": 6861152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071895.1", "url": "https://www.ensembl.org/id/ENSGALT00010071895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044585.1", "url": "https://www.ensembl.org/id/ENSGALP00010044585.1" } ] } }, { "isoform_ac": "A0A8V1ALX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1/entry#A0A8V1ALX1-1", "sequence": { "sequence": "MKSTARPWSAVSKQGSHGVDRGKSLSTASSGMKTSKSSTSLAFESRLSKLKRACSDDMLTKPGVTAASGVSRLKKTITTGAISELAESRLKPSTGTVSTAKRTGIPAPREISSSVSRERAVLRGQANTRKTQPSPTSSGTPTPTKHVRPTSKSKQESETGDKAVLESQVKELLAEAKTKDSEITKLRCELKKCKEKGSLNPEGMGASDQNVETLSPVDIDPLIRTLQEKNRTFQKELASLGEENRVLKEKLLYLENSPLSDTTTSSGGDSSLPTPTTQESSFGSPSKNVLRGETVEHRQRVNGGTLRNSASSSSDVTKASLSPDASDFEHIADIPSRPASSNSNHFKGSKCSTTGSSPNNISDLSVASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVEEKALLETSFRQHRDRAEQLGQENEKLMTLLQERSKSEESRAQEGKVLELEQKCAEVLEKAQFEREKLLNIQQQLTSSLRSLEREHQDAQQVIKGLRDENEKLLKLLEVEQQSNSTVTKTLEDCKIALEGLKIENGSLKTQLESEKQKAAEINAMGCTTDNSEVQELLKVAHAEKDQLEASCTELKQELLKANSELKHVQGLLSKAENECGQLKEVCERQAEQLSRTSQKLQEKTSENEADIKNLKETIFELEDQVEQHRAIKLHNNQIISDLESKTMKLEEQKQDIERQLKALTKQMKEDTEEWKRFQADLQTAVVVANDIKCEAQQELRVVKRKLQEEEEKSARLQKELDEVKGNNRLTAEEVESIETDTANRWQGVCISRASPTPSESAATVKSLIKSFDLGCSGSTGQNITVQKVPRSPLSGIPVRTAPAAAVSPMQRHSVYNNTKPASKGVVKHTDLSDLPLADLLKGRNEELKPDHYLRKSPSLESLSKPPMAFSSRMLNSTPSSLKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQDKKRNLLLAFQAAESVGIKPSLELSEMMYTDRPDWQSVMQYVAQIYKYFET", "length": 1053, "header": "tr|A0A8V1ALX1-1|A0A8V1ALX1_CHICK Isoform 1 of Sperm antigen with calponin homology and coiled-coil domains 1 OS=Gallus gallus OX=9031 GN=SPECC1 PE=1 SV=1 CANONICAL=A0A8V1ALX1-1" }, "locus": { "chromosome": "19", "start_pos": 6910038, "end_pos": 6850241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071897.1", "url": "https://www.ensembl.org/id/ENSGALT00010071897.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044587.1", "url": "https://www.ensembl.org/id/ENSGALP00010044587.1" } ] } }, { "isoform_ac": "A0A8V1ANI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1/entry#A0A8V1ANI2-1", "sequence": { "sequence": "MGNQPGRVEEHDQGTVSTAKRTGIPAPREISSSVSRERAVLRGQANTRKTQPSPTSSGTPTPTKHVRPTSKSKQESETGDKAVLESQVKELLAEAKTKDSEITKLRCELKKCKEKGSLNPEGMGASDQNVETLSPVDIDPLIRTLQEKNRTFQKELASLGEENRVLKEKLLYLENSPLSDTTTSSGGDSSLPTPTTQESSFGSPSKNVLRGETVEHRQRVNGGTLRNSASSSSDVTKASLSPDASDFEHIADIPSRPASSNSNHFKGSKCSTTGSSPNNISDLSVASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVEEKALLETSFRQHRDRAEQLGQENEKLMTLLQERSKSEESRAQEGKVLELEQKCAEVLEKAQFEREKLLNIQQQLTSSLRSLEREHQDAQQVIKGLRDENEKLLKLLEVEQQSNSTVTKTLEDCKIALEGLKIENGSLKTQLESEKQKAAEINAMGCTTDNSEVQELLKVAHAEKDQLEASCTELKQELLKANSELKHVQGLLSKAENECGQLKEVCERQAEQLSRTSQKLQEKTSENEADIKNLKETIFELEDQVEQHRAIKLHNNQIISDLESKTMKLEEQKQDIERQLKALTKQMKEDTEEWKRFQADLQTAVVVANDIKCEAQQELRVVKRKLQEEEEKSARLQKELDEVKGNNRLTAEEVESIETDTANRWQGVCISRASPTPSESAATVKSLIKSFDLGCSGSTGQNITVQKVPRSPLSGIPVRTAPAAAVSPMQRHSVYNNTKPASKGVVKHTDLSDLPLADLLKGRNEELKPDHYLRKSPSLESLSKPPMAFSSRMLNSTPSSLKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQDKKRNLLLAFQAAESVGIKPSLSLENISKSEGST", "length": 955, "header": "tr|A0A8V1ANI2-1|A0A8V1ANI2_CHICK Computationally mapped isoform of Sperm antigen with calponin homology and coiled-coil domains 1 OS=Gallus gallus OX=9031 GN=SPECC1 PE=1 SV=1 CANONICAL=A0A8V1ALX1-1" }, "locus": { "chromosome": "19", "start_pos": 6912450, "end_pos": 6861152, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071896.1", "url": "https://www.ensembl.org/id/ENSGALT00010071896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044586.1", "url": "https://www.ensembl.org/id/ENSGALP00010044586.1" } ] } }, { "isoform_ac": "E1BVU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1/entry#E1BVU7-1", "sequence": { "sequence": "MKSTARPWSAVSKQGSHGVDRGKSLSTASSGMKTSKSSTSLAFESRLSKLKRACSDDMLTKPGVTAASGVSRLKKTITTGAISELAESRLKPSTGTVSTAKRTGIPAPREISSSVSRERAVLRGQANTRKTQPSPTSSGTPTPTKHVRPTSKSKQESETGDKAVLESQVKELLAEAKTKDSEITKLRCELKKCKEKGSLNPEGMGASDQNVETLSPVDIDPLIRTLQEKNRTFQKELASLGEENRVLKEKLLYLENSPLSDTTTSSGGDSSLPTPTTQESSFGSPSKNVLRGETVEHRQRVNGGTLRNSASSSSDVTKASLSPDASDFEHIADIPSRPASSNSNHFKGSKCSTTGSSPNNISDLSVASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVEEKALLETSFRQHRDRAEQLGQENEKLMTLLQERSKSEESRAQEGKVLELEQKCAEVLEKAQFEREKLLNIQQQLTSSLRSLEREHQDAQQVIKGLRDENEKLLKLLEVEQQSNSTVTKTLEDCKIALEGLKIENGSLKTQLESEKQKAAEINAMGCTTDNSEVQELLKVAHAEKDQLEASCTELKQELLKANSELKHVQGLLSKAENECGQLKEVCERQAEQLSRTSQKLQEKTSENEADIKNLKETIFELEDQVEQHRAIKLHNNQIISDLESKTMKLEEQKQDIERQLKALTKQMKEDTEEWKRFQADLQTAVVVANDIKCEAQQELRVVKRKLQEEEEKSARLQKELDEVKGNNRCLISTS", "length": 777, "header": "tr|E1BVU7-1|E1BVU7_CHICK Computationally mapped isoform of Sperm antigen with calponin homology and coiled-coil domains 1 OS=Gallus gallus OX=9031 GN=SPECC1 PE=1 SV=5 CANONICAL=A0A8V1ALX1-1" }, "locus": { "chromosome": "19", "start_pos": 6886718, "end_pos": 6850241, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071894.1", "url": "https://www.ensembl.org/id/ENSGALT00010071894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044584.1", "url": "https://www.ensembl.org/id/ENSGALP00010044584.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 799, "start_aa": "Thr", "end_pos": 799, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr799", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q5M775-1", "protein_name": "Cytospin-B", "gene_name": "SPECC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSAAKPWNPAIRAGGHGPDRVRPLPAASSGMKSSKSSTSLAFESRLSRLKRASSEDTLNKPGSTAASGVVRLKKTATAGAISELTESRLRSGTGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTPSTKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTLNAEGTDALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHSPNSEGAASHTGDSSCPTSITQESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELGDVQGHGRVVTSRAAPPPVDEEPESSEVDAAGRWPGVCVSRTSPTPPESATTVKSLIKSFDLGRPGGAGQNISVHKTPRSPLSGIPVRTAPAAAVSPMQRHSTYSSVRPASRGVTQRLDLPDLPLSDILKGRTETLKPDPHLRKSPSLESLSRPPSLGFGDTRLLSASTRAWKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQEKKRNLLLAFEAAESVGIKPSLELSEMLYTDRPDWQSVMQYVAQIYKYFET", "length": 1068 }, "evidence": [ { "id": "A0A8V1ALX1", "url": "https://omabrowser.org/oma/group/A0A8V1ALX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ], "pmid": "" }, { "name": "apical part of cell", "id": "GO:0045177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 825, "end_pos": 827, "annotation": "n_glycosylation_sequon" }, { "start_pos": 859, "end_pos": 861, "annotation": "n_glycosylation_sequon" }, { "start_pos": 918, "end_pos": 920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX1" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 947, "end_pos": 1052, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 136, 799 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 825, "end_pos": 827 }, { "start_pos": 859, "end_pos": 861 }, { "start_pos": 918, "end_pos": 920 }, { "start_pos": 971, "end_pos": 973 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANI9-1", "uniprot_ac": "A0A8V1ANI9", "uniprot_id": "A0A8V1ANI9_CHICK", "mass": { "chemical_mass": 70369.0, "monoisotopic_mass": 70369.0 }, "refseq": {}, "gene_names": [ { "name": "SEPTIN9", "type": "recommended", "evidence": [ { "id": "A0A8V1ANI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ] } ], "protein_names": [ { "name": "Septin 9", "type": "synonym", "evidence": [ { "id": "A0A8V1ANI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEPTIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9", "locus": { "chromosome": "18", "start_pos": 4468414, "end_pos": 4363753, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029726", "url": "https://www.ensembl.org/id/ENSGALG00010029726" } ] } } ], "crossref": [ { "id": "A0A8V1ANI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417347", "url": "https://www.ncbi.nlm.nih.gov/gene/417347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKB5", "url": "https://www.orthodb.org/?gene=A0A8V1AKB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALX9", "url": "https://www.orthodb.org/?gene=A0A8V1ALX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANI9", "url": "https://www.orthodb.org/?gene=A0A8V1ANI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APY5", "url": "https://www.orthodb.org/?gene=A0A8V1APY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AKB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPEGQHEEIDILRDHPDLQWETAQAQRPDQPHSELPVGKREEKRRALGMETHFCPEALKRSFEVEEVDQSSNSSTPQRRTPNPLLRSTVSSSTQKFQELGARNSEPSARHADPTAQRSPKAPLRRVEHSGPKLPEPVSRRTEISIDISSKQVENSTSGLSRFGLKRADVLGHKAPEPTPRRTEITLGKPQEPGLRRADAPASKIPEMPQRRAEPPSAPMPDVATKRVEIQVAKAAEVPTPLARQVESMEPVPTPQPPQAEPKPQPVLMESPPKREEGPEAVPSPVPGMTDAVRDAGPKQAAPARPDKPAADFGYVGIDAILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHEIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEININRKKRIPDTRVHCCIYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERDYFKQRITADLLANGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDQEYQVNGRRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGQSSLSNGVTDKELVANEM", "length": 624, "header": "tr|A0A8V1ANI9-1|A0A8V1ANI9_CHICK Isoform 1 of Septin 9 OS=Gallus gallus OX=9031 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A8V1ANI9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9/entry#A0A8V1AKB5-1", "sequence": { "sequence": "MLNISRSNGEGPDFSSELPVGKREEKRRALGMETHFCPEALKRSFEVEEVDQSSNSSTPQRRTPNPLLRSTVSSSTQKFQELGARNSEPSARHADPTAQRSPKAPLRRVEHSGPKLPEPVSRRTEISIDISSKQVENSTSGLSRFGLKRADVLGHKAPEPTPRRTEITLGKPQEPGLRRADAPASKIPEMPQRRAEPPSAPMPDVATKRVEIQVAKAAEVPTPLARQVESMEPVPTPQPPQAEPKPQPVLMESPPKREEGPEAVPSPVPGMTDAVRDAGPKQAAPARPDKPAADFGYVGIDAILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHEIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEININRKKRIPDTRVHCCIYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERDYFKQRITADLLANGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDQEYQVNGRRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGQSSLSNGVTDKELVANEM", "length": 605, "header": "tr|A0A8V1AKB5-1|A0A8V1ANI9_CHICK Computationally mapped isoform of Septin 9 OS=Gallus gallus OX=9031 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A8V1ANI9-1" }, "locus": { "chromosome": "18", "start_pos": 4457265, "end_pos": 4391564, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071906.1", "url": "https://www.ensembl.org/id/ENSGALT00010071906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044596.1", "url": "https://www.ensembl.org/id/ENSGALP00010044596.1" } ] } }, { "isoform_ac": "A0A8V1ALX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9/entry#A0A8V1ALX9-1", "sequence": { "sequence": "MRKSTYSGITRTSSGRLRRLSDQTSPTLKRSFEVEEVDQSSNSSTPQRRTPNPLLRSTVSSSTQKFQELGARNSEPSARHADPTAQRSPKAPLRRVEHSGPKLPEPVSRRTEISIDISSKQVENSTSGLSRFGLKRADVLGHKAPEPTPRRTEITLGKPQEPGLRRADAPASKIPEMPQRRAEPPSAPMPDVATKRVEIQVAKAAEVPTPLARQVESMEPVPTPQPPQAEPKPQPVLMESPPKREEGPEAVPSPVPGMTDAVRDAGPKQAAPARPDKPAADFGYVGIDAILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHEIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEININRKKRIPDTRVHCCIYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERDYFKQRITADLLANGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDQEYQVNGRRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGQSSLSNGVTDKELVANEM", "length": 592, "header": "tr|A0A8V1ALX9-1|A0A8V1ALX9_CHICK Computationally mapped isoform of Septin 9 OS=Gallus gallus OX=9031 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A8V1ANI9-1" }, "locus": { "chromosome": "18", "start_pos": 4457265, "end_pos": 4364166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071908.1", "url": "https://www.ensembl.org/id/ENSGALT00010071908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044598.1", "url": "https://www.ensembl.org/id/ENSGALP00010044598.1" } ] } }, { "isoform_ac": "A0A8V1ANI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9/entry#A0A8V1ANI9-1", "sequence": { "sequence": "MSSPEGQHEEIDILRDHPDLQWETAQAQRPDQPHSELPVGKREEKRRALGMETHFCPEALKRSFEVEEVDQSSNSSTPQRRTPNPLLRSTVSSSTQKFQELGARNSEPSARHADPTAQRSPKAPLRRVEHSGPKLPEPVSRRTEISIDISSKQVENSTSGLSRFGLKRADVLGHKAPEPTPRRTEITLGKPQEPGLRRADAPASKIPEMPQRRAEPPSAPMPDVATKRVEIQVAKAAEVPTPLARQVESMEPVPTPQPPQAEPKPQPVLMESPPKREEGPEAVPSPVPGMTDAVRDAGPKQAAPARPDKPAADFGYVGIDAILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHEIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEININRKKRIPDTRVHCCIYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERDYFKQRITADLLANGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDQEYQVNGRRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGQSSLSNGVTDKELVANEM", "length": 624, "header": "tr|A0A8V1ANI9-1|A0A8V1ANI9_CHICK Isoform 1 of Septin 9 OS=Gallus gallus OX=9031 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A8V1ANI9-1" }, "locus": { "chromosome": "18", "start_pos": 4457265, "end_pos": 4364144, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071907.1", "url": "https://www.ensembl.org/id/ENSGALT00010071907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044597.1", "url": "https://www.ensembl.org/id/ENSGALP00010044597.1" } ] } }, { "isoform_ac": "A0A8V1APY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9/entry#A0A8V1APY5-1", "sequence": { "sequence": "MERDRISALKRSFEVEEVDQSSNSSTPQRRTPNPLLRSTVSSSTQKFQELGARNSEPSARHADPTAQRSPKAPLRRVEHSGPKLPEPVSRRTEISIDISSKQVENSTSGLSRFGLKRADVLGHKAPEPTPRRTEITLGKPQEPGLRRADAPASKIPEMPQRRAEPPSAPMPDVATKRVEIQVAKAAEVPTPLARQVESMEPVPTPQPPQAEPKPQPVLMESPPKREEGPEAVPSPVPGMTDAVRDAGPKQAAPARPDKPAADFGYVGIDAILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHEIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEININRKKRIPDTRVHCCIYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERDYFKQRITADLLANGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDQEYQVNGRRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGQSSLSNGVTDKELVANEM", "length": 573, "header": "tr|A0A8V1APY5-1|A0A8V1APY5_CHICK Computationally mapped isoform of Septin 9 OS=Gallus gallus OX=9031 GN=SEPTIN9 PE=1 SV=1 CANONICAL=A0A8V1ANI9-1" }, "locus": { "chromosome": "18", "start_pos": 4457265, "end_pos": 4391586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071905.1", "url": "https://www.ensembl.org/id/ENSGALT00010071905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044595.1", "url": "https://www.ensembl.org/id/ENSGALP00010044595.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 180, "start_aa": "Thr", "end_pos": 180, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr180", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 255, "start_aa": "Thr", "end_pos": 255, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr255", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "septin ring", "id": "GO:0005940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005940", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "non-motile cilium", "id": "GO:0097730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "septin complex", "id": "GO:0031105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031105", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "cell division site", "id": "GO:0032153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032153", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" }, { "name": "positive regulation of non-motile cilium assembly", "id": "GO:1902857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANI9" }, { "id": "PS51719", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Septin-type G", "eco_id": "ECO_0000259", "start_pos": 333, "end_pos": 605, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 180, 255 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANK3-1", "uniprot_ac": "A0A8V1ANK3", "uniprot_id": "A0A8V1ANK3_CHICK", "mass": { "chemical_mass": 82203.0, "monoisotopic_mass": 82203.0 }, "refseq": {}, "gene_names": [ { "name": "SEC14L1", "type": "recommended", "evidence": [ { "id": "A0A8V1ANK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ] } ], "protein_names": [ { "name": "SEC14-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1ANK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of RIGI, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of RIGI with MAVS/IPS1, an important step in signal propagation. May also regulate the SLC18A3 and SLC5A7 cholinergic transporters.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ5#function" }, { "database": "UniProtKB", "id": "ARBA00056647", "url": "https://www.uniprot.org/uniprotkb/ARBA00056647#function" }, { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3#function" }, { "database": "UniProtKB", "id": "A0A8V1AF12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF12#function" }, { "database": "UniProtKB", "id": "A0A8V1AKE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEC14L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3", "locus": { "chromosome": "18", "start_pos": 4705135, "end_pos": 4743471, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029734", "url": "https://www.ensembl.org/id/ENSGALG00010029734" } ] } } ], "crossref": [ { "id": "A0A8V1ANK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417350", "url": "https://www.ncbi.nlm.nih.gov/gene/417350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AEWTCFD", "url": "https://omabrowser.org/oma/group/AEWTCFD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF12", "url": "https://www.orthodb.org/?gene=A0A8V1AF12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKE9", "url": "https://www.orthodb.org/?gene=A0A8V1AKE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALZ5", "url": "https://www.orthodb.org/?gene=A0A8V1ALZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANK3", "url": "https://www.orthodb.org/?gene=A0A8V1ANK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APZ5", "url": "https://www.orthodb.org/?gene=A0A8V1APZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23324:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23324:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AF12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQKYQSPIRVYKHPFELIMAAYERRFPTCPLIPMFVASDTVSEYKSEDEAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNRRERTLHIEAYNETFSNRVIINEHCSYTVHPDNEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLKQLEEEGITFVPRWTPPVACKLESSTSHTRRPVSPAVNVPDSATKEGLNNKEILNISSSPSELTAGTPDDKLDADYIKRYLGDLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHQVDYILDTWNPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRKKFLIYAGNDYQGPGGLLDYIDKEIIPDFLGGECMCEVPEGGLVPKSLYRTAEELENEDIKLWTETIYQSASVFKGAPHEVLIQIVDASSVITWDFDVCKGDIVFNIFHSKRAPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGCDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISRWWFC", "length": 719, "header": "tr|A0A8V1ANK3-1|A0A8V1ANK3_CHICK Isoform 1 of SEC14-like protein 1 OS=Gallus gallus OX=9031 GN=SEC14L1 PE=4 SV=1 CANONICAL=A0A8V1ANK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3/entry#A0A8V1AF12-1", "sequence": { "sequence": "MLRRNKYTMKDGIGEPRGLKAVLQDFQQITLNQSPDLGTQNVGAYERRFPTCPLIPMFVASDTVSEYKSEDEAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNRRERTLHIEAYNETFSNRVIINEHCSYTVHPDNEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLKQLEEEGITFVPRWTPPVACKLESSTSHTRRPVSPAVNVPDSATKEGLNNKEILNISSSPSELTAGTPDDKLDADYIKRYLGDLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHQVDYILDTWNPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRKKFLIYAGNDYQGPGGLLDYIDKEIIPDFLGGECMCEVPEGGLVPKSLYRTAEELENEDIKLWTETIYQSASVFKGAPHEVLIQIVDASSVITWDFDVCKGDIVFNIFHSKRAPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGCDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR", "length": 737, "header": "tr|A0A8V1AF12-1|A0A8V1AF12_CHICK Computationally mapped isoform of SEC14-like protein 1 OS=Gallus gallus OX=9031 GN=SEC14L1 PE=4 SV=1 CANONICAL=A0A8V1ANK3-1" }, "locus": { "chromosome": "18", "start_pos": 4737049, "end_pos": 4708332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071929.1", "url": "https://www.ensembl.org/id/ENSGALT00010071929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044619.1", "url": "https://www.ensembl.org/id/ENSGALP00010044619.1" } ] } }, { "isoform_ac": "A0A8V1AKE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3/entry#A0A8V1AKE9-1", "sequence": { "sequence": "MSGEEMNLRGTTGISEVFVSEKRWFFSFGSSTGTRCVCLLLELTFITAAMVQKYQSPIRVYKHPFELIMAAYERRFPTCPLIPMFVASDTVSEYKSEDEAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNRRERTLHIEAYNETFSNRVIINEHCSYTVHPDNEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLKQLEEEGITFVPRWTPPVACKLESSTSHTRRPVSPAVNVPDSATKEGLNNKEILNISSSPSELTAGTPDDKLDADYIKRYLGDLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHQVDYILDTWNPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRKKFLIYAGNDYQGPGGLLDYIDKEIIPDFLGGECMCEVPEGGLVPKSLYRTAEELENEDIKLWTETIYQSASVFKGAPHEVLIQIVDASSVITWDFDVCKGDIVFNIFHSKRAPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGCDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR", "length": 764, "header": "tr|A0A8V1AKE9-1|A0A8V1ANK3_CHICK Computationally mapped isoform of SEC14-like protein 1 OS=Gallus gallus OX=9031 GN=SEC14L1 PE=4 SV=1 CANONICAL=A0A8V1ANK3-1" }, "locus": { "chromosome": "18", "start_pos": 4742895, "end_pos": 4708332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071926.1", "url": "https://www.ensembl.org/id/ENSGALT00010071926.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044616.1", "url": "https://www.ensembl.org/id/ENSGALP00010044616.1" } ] } }, { "isoform_ac": "A0A8V1ALZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3/entry#A0A8V1ALZ5-1", "sequence": { "sequence": "MRRAASGRAALELTFITAAMVQKYQSPIRVYKHPFELIMAAYERRFPTCPLIPMFVASDTVSEYKSEDEAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNRRERTLHIEAYNETFSNRVIINEHCSYTVHPDNEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLKQLEEEGITFVPRWTPPVACKLESSTSHTRRPVSPAVNVPDSATKEGLNNKEILNISSSPSELTAGTPDDKLDADYIKRYLGDLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHQVDYILDTWNPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRKKFLIYAGNDYQGPGGLLDYIDKEIIPDFLGGECMCEVPEGGLVPKSLYRTAEELENEDIKLWTETIYQSASVFKGAPHEVLIQIVDASSVITWDFDVCKGDIVFNIFHSKRAPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGCDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR", "length": 734, "header": "tr|A0A8V1ALZ5-1|A0A8V1ALZ5_CHICK Computationally mapped isoform of SEC14-like protein 1 OS=Gallus gallus OX=9031 GN=SEC14L1 PE=4 SV=1 CANONICAL=A0A8V1ANK3-1" }, "locus": { "chromosome": "18", "start_pos": 4743425, "end_pos": 4708332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071928.1", "url": "https://www.ensembl.org/id/ENSGALT00010071928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044618.1", "url": "https://www.ensembl.org/id/ENSGALP00010044618.1" } ] } }, { "isoform_ac": "A0A8V1ANK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3/entry#A0A8V1ANK3-1", "sequence": { "sequence": "MVQKYQSPIRVYKHPFELIMAAYERRFPTCPLIPMFVASDTVSEYKSEDEAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNRRERTLHIEAYNETFSNRVIINEHCSYTVHPDNEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLKQLEEEGITFVPRWTPPVACKLESSTSHTRRPVSPAVNVPDSATKEGLNNKEILNISSSPSELTAGTPDDKLDADYIKRYLGDLTPMQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHQVDYILDTWNPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRKKFLIYAGNDYQGPGGLLDYIDKEIIPDFLGGECMCEVPEGGLVPKSLYRTAEELENEDIKLWTETIYQSASVFKGAPHEVLIQIVDASSVITWDFDVCKGDIVFNIFHSKRAPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGCDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISRWWFC", "length": 719, "header": "tr|A0A8V1ANK3-1|A0A8V1ANK3_CHICK Isoform 1 of SEC14-like protein 1 OS=Gallus gallus OX=9031 GN=SEC14L1 PE=4 SV=1 CANONICAL=A0A8V1ANK3-1" }, "locus": { "chromosome": "18", "start_pos": 4742294, "end_pos": 4706139, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071927.1", "url": "https://www.ensembl.org/id/ENSGALT00010071927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044617.1", "url": "https://www.ensembl.org/id/ENSGALP00010044617.1" } ] } }, { "isoform_ac": "A0A8V1APZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3/entry#A0A8V1APZ5-1", "sequence": { "sequence": "LENLPFSLQYLFALFGNLLYISSTFSPWVQLQQFLQCEVPEGGLVPKSLYRTAEELENEDIKLWTETIYQSASVFKGAPHEVLIQIVDASSVITWDFDVCKGDIVFNIFHSKRAPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGCDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISR", "length": 259, "header": "tr|A0A8V1APZ5-1|A0A8V1APZ5_CHICK Computationally mapped isoform of SEC14 like lipid binding 1 OS=Gallus gallus OX=9031 GN=SEC14L1 PE=4 SV=1 CANONICAL=A0A8V1ANK3-1" }, "locus": { "chromosome": "18", "start_pos": 4711525, "end_pos": 4708332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071925.1", "url": "https://www.ensembl.org/id/ENSGALT00010071925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044615.1", "url": "https://www.ensembl.org/id/ENSGALP00010044615.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LUY5-1", "protein_name": "SEC14-like protein 1", "gene_name": "SEC14L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVNEFRSEDGAIHVIERRCKLDIDAPRLLKKIAGVDYVYFIQKNSLNSRERTLHIEAHNETFSNRVIINELCCYSVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKQYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPAAAPSLETSLSCKKPAASLTVVVPDPTLKEGLSGEPLSTPSGAAEPTAGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKARETMCQSLTWRKQHQVDYILDTWHPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCEVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDRVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHSTPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISRWRFC", "length": 719 }, "evidence": [ { "id": "A0A8V1ANK3", "url": "https://omabrowser.org/oma/group/A0A8V1ANK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I5ZQG0-1", "protein_name": "SEC14-like protein 1", "gene_name": "Sec14l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVSEFKSEDGAIHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNSRDRTLHIEAHNETFSNRVIIHEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKHYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPPTGPSSETCSSSKNQAASAAVLVPDAAAVKEGLSGEVLSSPGTVAEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQVLQDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCDVPEGGLVPKSLYRTPEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDAASVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHTMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSHSSSMISSE", "length": 717 }, "evidence": [ { "id": "A0A8V1ANK3", "url": "https://omabrowser.org/oma/group/A0A8V1ANK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A8Y5H7-1", "protein_name": "SEC14-like protein 1", "gene_name": "Sec14l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQKYQSPVRVYKHPFELIMAAYERRFPTCPLIPMFVDSDTVSEFKSEDGALHVIERRCKLDIDAPRLLKKIAGVDYVYFVQKNSLNSRDRTLHIEAHNETFSNRVIIHEHCCYTVHPENEDWTCFEQSASLDIKSFFGFESTVEKIAMKHYTSNIKKGKEIIEYYLRQLEEEGITFVPRWTPPPVGPSETCSSSKNQVTSAAVLVPDAAAVMEGLSGENLSSPGTASEPVVGTPDDKLDADYIKRYLGDLTPLQESCLIRLRQWLQETHKGKIPKDEHILRFLRARDFNIDKAREIMCQSLTWRKQHQVDYILDTWTPPQVLLDYYAGGWHHHDKDGRPLYVLRLGQMDTKGLVRALGEEALLRYVLSINEEGLRRCEENTKVFGRPISSWTCLVDLEGLNMRHLWRPGVKALLRIIEVVEANYPETLGRLLILRAPRVFPVLWTLVSPFIDDNTRRKFLIYAGNDYQGPGGLLDYIDKEIIPDFLSGECMCDVPEGGLVPKSLYRTAEELENEDLKLWTETIYQSASVFKGAPHEILIQIVDASSVITWDFDVCKGDIVFNIYHSKRSPQPPKKDSLGAHSITSPGGNNVQLIDKVWQLGRDYSMVESPLICKEGESVQGSHVTRWPGFYILQWKFHTMPACAATNLPRVDDVLASLQVSSHKCKVMYYTEVIGSEDFRGSMTSLESSHSGFSQLSAATTSSSQSQSSSMISR", "length": 715 }, "evidence": [ { "id": "A0A8V1ANK3", "url": "https://omabrowser.org/oma/group/A0A8V1ANK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VMD6-1", "protein_name": "Protein real-time", "gene_name": "retm", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVQKFQSPVRVYKYPFELVMKAYERRFPTCPQMPIVLDCEVIKDESLEDGAKRNTSRRCKLAVDAPYIFKKLIGVDHVYFLQHNFLDLANRTLSIEAVNESFSSRIEIFERCRYYAHPDNSEWTCFDQSATLDIKNFFGFEHSMEKMGMKQYTQTTLKGKEIIEFFIGQLREEGITHVERWTSPSDATKSPTLDQASDQQHSILLDGDFIARSLGQLSPMQESKLLELRKMLDGVDDLERVPSYQTILRFLAARDWHVSQAYAMLCDSLRWRREHRIDALLAEYSKPAVVVEHFPGGWHHLDKDGRPVYILRLGHMDVKGLLKSLGMDGLLRLALHICEEGIQKINESAERLEKPVLNWSLLVDLEGLSMRHLWRPGIKALLNIIETVERNYPETMGRVLVVRAPRVFPIAWTIVSAFIDEHTRSKFLFYGPDCAHMKDGLAQYLDEEIVPDFLGGPCKTMIHEGGLVPKTLYKMNSLEDHDDEVTAELPTTAAAQALVPGKRLSANQQHDHRNLYKSVDLKAGFAHELLIRNEDPKSVLTWDFDVMRNDLHFTLYRVTQELPEKNDSAVSYFDLQDFVEGVNYFREEPTLICRHKESVQGSHVMHHNDSYLMHWFSPSGAQLNVFYEVLSSANYKGSMTSLQSAFSSNSSAASSVQSR", "length": 659 }, "evidence": [ { "id": "A0A8V1ANK3", "url": "https://omabrowser.org/oma/group/A0A8V1ANK3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" }, { "name": "choline transport", "id": "GO:0015871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015871", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" }, { "name": "negative regulation of RIG-I signaling pathway", "id": "GO:0039536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RIG-I binding", "id": "GO:0039552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 495, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ANK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" }, { "id": "PS50866", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50866" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GOLD", "eco_id": "ECO_0000259", "start_pos": 521, "end_pos": 674, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ANK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK3" }, { "id": "PS50904", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PRELI/MSF1", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 175, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANX6-1", "uniprot_ac": "A0A8V1ANX6", "uniprot_id": "A0A8V1ANX6_CHICK", "mass": { "chemical_mass": 240956.0, "monoisotopic_mass": 240956.0 }, "refseq": {}, "gene_names": [ { "name": "SDK2", "type": "recommended", "evidence": [ { "id": "A0A8V1ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ] } ], "protein_names": [ { "name": "Sidekick cell adhesion molecule 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Adhesion molecule that promotes lamina-specific synaptic connections in the retina. Expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PWY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWY1#function" }, { "database": "UniProtKB", "id": "ARBA00060218", "url": "https://www.uniprot.org/uniprotkb/ARBA00060218#function" }, { "database": "UniProtKB", "id": "A0A8V1AKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG2#function" }, { "database": "UniProtKB", "id": "A0A8V1AME0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME0#function" }, { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SDK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6", "locus": { "chromosome": "18", "start_pos": 9648123, "end_pos": 9694325, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029492", "url": "https://www.ensembl.org/id/ENSGALG00010029492" } ] } } ], "crossref": [ { "id": "ENSGALG00000031895", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031895", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395215", "url": "https://www.ncbi.nlm.nih.gov/gene/395215", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395215", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395215", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCTTVLY", "url": "https://omabrowser.org/oma/group/NCTTVLY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PWY1", "url": "https://www.orthodb.org/?gene=A0A1D5PWY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKG2", "url": "https://www.orthodb.org/?gene=A0A8V1AKG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AME0", "url": "https://www.orthodb.org/?gene=A0A8V1AME0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANX6", "url": "https://www.orthodb.org/?gene=A0A8V1ANX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-373756", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373756", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PWY1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PWY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PWY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPGSWGLLCAVVLALPGPPGAGAQDDVSPYFKTEPVRSQVHLEGNRLVLTCMAEGSWPLEFKWLHNSRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEDSETQQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKISPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVANVGGPADPIAPTIIVPPRNTSVVAGTSEVTMECVANARPLIKLHIIWKKDGVPISSGISDYSRRLTILNPTLGDSGYYECEAVLRSSSVPAVAEGAYLSVLEPPQFVKEPERHITAEMEKVVAIPCQAKGVPPPDMAWYKDASLIHPEQLSRFQLLADGSLQISGLLPDDTGMFQCFARNAAGEVQTTTYLAVTSIAPNITRGPQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLVSPAHLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSCGVTHDPSVDVRYIWEKDGAPLGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGGNDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPWTVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSLPEEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDTRSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGRGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSSSSMLVRWSDIPEADCNGLILGYKVMYKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAVPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPNGILEGYRLVYEPCMPVDGEGTAGASEGTRGGPGSASISAGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKSDSGNGSKANALTHGEMVSLDESSFPALELNNRRLSVKNSFCRKNGIYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEVSDSQGSDSEYEVDPAHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTPLSNSTSTQQGSLFRPKASRTPTPQTPGNPPSQPGTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2199, "header": "tr|A0A8V1ANX6-1|A0A8V1ANX6_CHICK Isoform 1 of Sidekick cell adhesion molecule 2 OS=Gallus gallus OX=9031 GN=SDK2 PE=3 SV=1 CANONICAL=A0A8V1ANX6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6/entry#A0A1D5PWY1-1", "sequence": { "sequence": "MARPGSWGLLCAVVLALPGPPGAGAQDDVSPYFKTEPVRSQVHLEGNRLVLTCMAEGSWPLEFKWLHNSRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEDSETQQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKISPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVANVGGPADPIAPTIIVPPRNTSVVAGTSEVTMECVANARPLIKLHIIWKKDGVPISSGISDYSRRLTILNPTLGDSGYYECEAVLRSSSVPAVAEGAYLSVLEPPQFVKEPERHITAEMEKVVAIPCQAKGVPPPDMAWYKDASLIHPEQLSRFQLLADGSLQISGLLPDDTGMFQCFARNAAGEVQTTTYLAVTSIAPNITRGPQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLVSPAHLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSCGVTHDPSVDVRYIWEKDGAPLGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGGNDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPWTVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSLPEEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDTRSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGRGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSSSSMLVRWSDIPEADCNGLILGYKVMYKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAVPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPNGILEGYRLVYEPCMPVDGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKSDSGNGSKANALTHGEMVSLDESSFPALELNNRRLSVKNSFCRKNGIYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEVSDSQGSDSEYEVDPAHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTPLSNSTSTQQGSLFRPKASRTPTPQTPGNPPSQPGTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2177, "header": "tr|A0A1D5PWY1-1|A0A1D5PWY1_CHICK Computationally mapped isoform of Sidekick cell adhesion molecule 2 OS=Gallus gallus OX=9031 GN=SDK2 PE=3 SV=2 CANONICAL=A0A8V1ANX6-1" }, "locus": { "chromosome": "18", "start_pos": 9689330, "end_pos": 9648186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071300.1", "url": "https://www.ensembl.org/id/ENSGALT00010071300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043991.1", "url": "https://www.ensembl.org/id/ENSGALP00010043991.1" } ] } }, { "isoform_ac": "A0A8V1AKG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6/entry#A0A8V1AKG2-1", "sequence": { "sequence": "MGSCWTLQGQRGAAEPVMKDKRADPADDVSPYFKTEPVRSQVHLEGNRLVLTCMAEGSWPLEFKWLHNSRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEDSETQQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKISPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVANVGGPADPIAPTIIVPPRNTSVVAGTSEVTMECVANARPLIKLHIIWKKDGVPISSGISDYSRRLTILNPTLGDSGYYECEAVLRSSSVPAVAEGAYLSVLEPPQFVKEPERHITAEMEKVVAIPCQAKGVPPPDMAWYKDASLIHPEQLSRFQLLADGSLQISGLLPDDTGMFQCFARNAAGEVQTTTYLAVTSIAPNITRGPQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLVSPAHLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSCGVTHDPSVDVRYIWEKDGAPLGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGGNDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPWTVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSLPEEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDTRSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGRGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSSSSMLVRWSDIPEADCNGLILGYKVMYKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAVPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPNGILEGYRLVYEPCMPVDGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKSDSGNGSKANALTHGEMVSLDESSFPALELNNRRLSVKNSFCRKNGIYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEVSDSQGSDSEYEVDPAHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTPLSNSTSTQQGSLFRPKASRTPTPQTPGNPPSQPGTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2177, "header": "tr|A0A8V1AKG2-1|A0A8V1ANX6_CHICK Computationally mapped isoform of Sidekick cell adhesion molecule 2 OS=Gallus gallus OX=9031 GN=SDK2 PE=3 SV=1 CANONICAL=A0A8V1ANX6-1" }, "locus": { "chromosome": "18", "start_pos": 9694211, "end_pos": 9648186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071302.1", "url": "https://www.ensembl.org/id/ENSGALT00010071302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043993.1", "url": "https://www.ensembl.org/id/ENSGALP00010043993.1" } ] } }, { "isoform_ac": "A0A8V1AME0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6/entry#A0A8V1AME0-1", "sequence": { "sequence": "MARPGSWGLLCAVVLALPGPPGAGAQDDVSPYFKTEPVRSQVHLEGNRLVLTCMAEGSWPLEFKWLHNSRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEDSETQQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKISPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVANVGGPADPIAPTIIVPPRNTSVVAGTSEVTMECVANARPLIKLHIIWKKDGVPISSGISDYSRRLTILNPTLGDSGYYECEAVLRSSSVPAVAEGAYLSVLEPPQFVKEPERHITAEMEKVVAIPCQAKGVPPPDMAWYKDASLIHPEQLSRFQLLADGSLQISGLLPDDTGMFQCFARNAAGEVQTTTYLAVTSIAPNITRGPQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLVSPAHLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSCGVTHDPSVDVRYIWEKDGAPLGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGGNDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPWTVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSLPEEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDTRSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGRGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSSSSMLVRWSDIPEADCNGLILGYKVMYKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTHLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAVPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPNGILEGYRLVYEPCMPVDGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKSDSGNGSKANALTHGEMVSLDESSFPALELNNRRLSVKNSFCRKNGIYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEVSDSQGSDSEYEVDPAHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTPLSNSTSTQQGSLFRPKASRTPTPQTPGNPPSQPGTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2158, "header": "tr|A0A8V1AME0-1|A0A8V1AME0_CHICK Computationally mapped isoform of Sidekick cell adhesion molecule 2 OS=Gallus gallus OX=9031 GN=SDK2 PE=3 SV=1 CANONICAL=A0A8V1ANX6-1" }, "locus": { "chromosome": "18", "start_pos": 9689330, "end_pos": 9648186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071301.1", "url": "https://www.ensembl.org/id/ENSGALT00010071301.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043992.1", "url": "https://www.ensembl.org/id/ENSGALP00010043992.1" } ] } }, { "isoform_ac": "A0A8V1ANX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6/entry#A0A8V1ANX6-1", "sequence": { "sequence": "MARPGSWGLLCAVVLALPGPPGAGAQDDVSPYFKTEPVRSQVHLEGNRLVLTCMAEGSWPLEFKWLHNSRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEDSETQQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKISPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVANVGGPADPIAPTIIVPPRNTSVVAGTSEVTMECVANARPLIKLHIIWKKDGVPISSGISDYSRRLTILNPTLGDSGYYECEAVLRSSSVPAVAEGAYLSVLEPPQFVKEPERHITAEMEKVVAIPCQAKGVPPPDMAWYKDASLIHPEQLSRFQLLADGSLQISGLLPDDTGMFQCFARNAAGEVQTTTYLAVTSIAPNITRGPQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLVSPAHLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSCGVTHDPSVDVRYIWEKDGAPLGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGGNDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPWTVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSLPEEPPSAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDTRSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGRGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSSSSMLVRWSDIPEADCNGLILGYKVMYKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAVPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPNGILEGYRLVYEPCMPVDGEGTAGASEGTRGGPGSASISAGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKSDSGNGSKANALTHGEMVSLDESSFPALELNNRRLSVKNSFCRKNGIYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEVSDSQGSDSEYEVDPAHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTPLSNSTSTQQGSLFRPKASRTPTPQTPGNPPSQPGTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2199, "header": "tr|A0A8V1ANX6-1|A0A8V1ANX6_CHICK Isoform 1 of Sidekick cell adhesion molecule 2 OS=Gallus gallus OX=9031 GN=SDK2 PE=3 SV=1 CANONICAL=A0A8V1ANX6-1" }, "locus": { "chromosome": "18", "start_pos": 9689330, "end_pos": 9648186, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071299.1", "url": "https://www.ensembl.org/id/ENSGALT00010071299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043990.1", "url": "https://www.ensembl.org/id/ENSGALP00010043990.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1940, "start_aa": "Thr", "end_pos": 1940, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1940", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395215", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395215", "resource": "KEGG Pathway" }, { "id": "R-GGA-373756", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373756", "resource": "Reactome", "description": "SDK interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K999-1", "protein_name": "Sidekick cell adhesion molecule 2", "gene_name": "Sdk2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSMWRLPIWTLLALHRIHSAGAQDDVPPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTRFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIKAPRISSFPRPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTMECVANARPLIKLHIVWKKDGALLSNGISDYNRRLTITNPMVSDAGYYECEAMLRSSSVAPVTRGAYLSVLEPPQFVREPERHITAEMEKVVDIPCRAKGVPPPSITWYKDAALVEVGKLTRFKQRSDGGLQISGLLPDDTGMVQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTVRYVWEKDGATLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHPVATLSTMERRAINLTWAKPFDGNSPLMRYILEMSENNAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTAIRFTWNAPSPQFINGINQGYKLIAWEPTQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWVVEAQVGMIGEGEEWLLIYQLSNEPDARSMEVPDLNPFTYYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHTVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQARFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPATPNGIILAYQITHRLNATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLTKHRRYEIRMSVYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDNQNGDIQGYKIYFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPGSVKFSELTTTSVNVSWDAPQFPNGPLEGYRLVYEPCTPVDGVSKIVTVDVKGNSPLWLKVKDLAEGMTYRFRIKAKTFTYGPEIEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKASPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKTDAGGNTKSGALGHGEMLSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDTNTQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHVTVPNSNSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2175 }, "evidence": [ { "id": "A0A8V1ANX6", "url": "https://omabrowser.org/oma/group/A0A8V1ANX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O97394-1", "protein_name": "Protein sidekick", "gene_name": "sdk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKSAASSLRRRRPKTTITATLAIEMPSQPKLASLLAVLVLLCYCDSCFFCYADANLQQQNSIVQQQQLQAPRFTTHPSSSGSIVSEGSTKILQCHALGYPQPTYRWLKDGVPVGDFSSSQFYRFHSTRREDAGSYQCIARNDAGSIFSEKSDVVVAYMGIFENTTEGRLTVISGHPAIFDMPPIESIPVPSVMWQSEDGPLNYDIKYAFTHANQLIILSADENDRKGYRAKAINTQLGKEESSAFVHLNVSGDPYIEVAPEIIVRPQDVKVKVGTGVVELQCIANARPLHELETLWLKDGLAVETAGVRHTLNDPWNRTLALLQANSSHSGEYTCQVRLRSGGYPAVSASARLQILEPPLFFTPMRAETFGEFGGQVQLTCDVVGEPTPQVKWFRNAESVDAHIESGRYTLNTDNTLVIKKLILDDAAMFQCLAINEAGENSASTWLRVKTSAPIMELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLVDISSRVQILESGDLLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPSNVKVERLPEPQQRSINVSWTPGFDGNSPISKFIIQRREVSELEKFVGPVPDPLLNWITELSNVSADQRWILLENLKAATVYQFRVSAVNRVGEGSPSEPSNVVELPQEAPSGPPVGFVGSARSMSEIITQWQPPLEEHRNGQILGYILRYRLFGYNNVPWSYQNITNEAQRNFLIQELITWKDYIVQIAAYNNMGVGVYTEGSKIKTKEGVPEAPPTNVKVEAINSTAARCRWTPPNPQQINGINQGYKIQAWQRRLIDGEWRDIERRMKTVPPSLIDPLAEQTAILGGLEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDVPDEVTGLHFDDVSDRSVKVLWAPPRASNGILTGYTVRYQVKDRPDTLKSFNLTADDTELTVNQLQATTHYWFEIVAWTRVGSGIPKTATIQSGVEPVLPHAPTALALSNIEAFSVVLQFTPGFDGNSSITKWKVEGQTARNMTWFTICEINDPDAETLTVTGLVPFTQYRLRLSASNVVGSSKPSEATKDFQTIQARPKHPPFNVTVRAMSAQQLRVRWIPLQQTEWYGNPRGYNISYKQLVKTPGTIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESDTAVERTREAVPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQQVLHKTIPNNATFTTTLTELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDTPGVPSNVSFPDVSLTMARIIWDVPVDPNGKILAYQVTYTLNGSAMLNYSREFPPSDRTFRATELLPGKYYSFSCTAQTRLGWGKIATALVYTTNNRERPQAPSVPQISRSQIQAHQITFSWTPGRDGFAPLRYYTVEMRENEGRWQPLPERVDPSLSSFTAVGLRPYMTYQFRIQATNDLGPSAFSRESVIVRTLPAAPAVGVGGLKVVPITTTSVRVQWSALETALWNGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQQDRNYEIVVLPFNSQGPGPATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVKTLPGVPSAPLHLRFSDITMQSLEVTWDPPKFLNGEILGYLVTYETTEENEKFSKQVKQKVSNTTLRVQNLEEEVTYTFTVRAQTSVDYGPGISENVTTGPQDGSPVAPRDLILTKTLSSVEMHWINGPSGRGPILGYLIEAKKRDDSRWTKIEQTRKGMMQDFTVSYHILMPSTAYTFRVIAYNRYGISFPVYSKDSILTPSKLHLEYGYLQHKPFYRQTWFMVSLAATSIVIIVMVIAVLCVKSKSYKYKQEAQKTLEESMAMSIDERQELALELYRSRHGVGTGTLNSVGTLRSGTLGTLGRKSTSRPPPGVHLGKSPPRPSPASVAYHSDEESLKCYDENPDDSSVTEKPSEVSSSEASQHSESENESVRSDPHSFVNHYANVNDSLRQSWKKTKPVRNYSSYTDSEPEGSAVMSLNGGQIIVNNMARSRAPLPGFSSFV", "length": 2224 }, "evidence": [ { "id": "A0A8V1ANX6", "url": "https://omabrowser.org/oma/group/A0A8V1ANX6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q58EX2-1", "protein_name": "Protein sidekick-2", "gene_name": "SDK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEMMSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTTVTNSTSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2172 }, "evidence": [ { "id": "A0A8V1ANX6", "url": "https://omabrowser.org/oma/group/A0A8V1ANX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6V4S5-1", "protein_name": "Protein sidekick-2", "gene_name": "Sdk2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSSMWRLPLWTLLALHRIHSAGAQDDVPPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTRFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKRQSVNHGEAAVIRAPRISSFPRPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTMECVANARPLIKLHIVWKKDGAPLSSGISDYNRRLTIANPTVSDAGYYECEAMLRSSSVAPVTRGAYLSVLEPPQFVREPERHITAEMEKVVDIPCRAKGVPPPSITWYKDAALVEVGKLTRFKQRSDGGLQISGLLPDDTGMLQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTVRYVWEKDGATLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHPVATLSTVERRAINLTWAKPFDGNSPLMRYVLEMSENNAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPAQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWVVEAQVGVIGEGEEWLLIYQLGNEPDARSMEVPDLNPFTYYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDIAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYGRSDGHGKTLSHTVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRIRYRELLYDGLRGFTLRGINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLSKHRRYEIRMSIYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDNQNGDIQGYKIYFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTRGQTQQAAPSAPGSVKFSELTTTSVNVSWDAPQFPNGPLEGYRLVYEPCTPVDGVSKIVTVDVKGNSPLWLKVKDLAEGMTYRFRIKAKTFTYGPEIEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKASPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKTDSGGNTKSGALGHGEMLSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDTNTQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHVTVPNSNSTQQGSLFRPKASRTPTPQNPPNPQSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2176 }, "evidence": [ { "id": "A0A8V1ANX6", "url": "https://omabrowser.org/oma/group/A0A8V1ANX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "pmid": "" }, { "name": "retina layer formation", "id": "GO:0010842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "pmid": "" }, { "name": "camera-type eye photoreceptor cell differentiation", "id": "GO:0060219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1107, "end_pos": 1109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1210, "end_pos": 1212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1261, "end_pos": 1263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1346, "end_pos": 1348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1462, "end_pos": 1464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1580, "end_pos": 1582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1593, "end_pos": 1595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1675, "end_pos": 1677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1694, "end_pos": 1696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1746, "end_pos": 1748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1842, "end_pos": 1844, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1995, "end_pos": 1997, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2144, "end_pos": 2146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 809, "end_pos": 811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 941, "end_pos": 943, "annotation": "n_glycosylation_sequon" }, { "start_pos": 953, "end_pos": 955, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 597, "end_pos": 693, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ANX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 113, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1940 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1107, "end_pos": 1109 }, { "start_pos": 1210, "end_pos": 1212 }, { "start_pos": 1261, "end_pos": 1263 }, { "start_pos": 1346, "end_pos": 1348 }, { "start_pos": 1462, "end_pos": 1464 }, { "start_pos": 1580, "end_pos": 1582 }, { "start_pos": 1593, "end_pos": 1595 }, { "start_pos": 1675, "end_pos": 1677 }, { "start_pos": 1694, "end_pos": 1696 }, { "start_pos": 1746, "end_pos": 1748 }, { "start_pos": 1842, "end_pos": 1844 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 1995, "end_pos": 1997 }, { "start_pos": 2144, "end_pos": 2146 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 614, "end_pos": 616 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 809, "end_pos": 811 }, { "start_pos": 941, "end_pos": 943 }, { "start_pos": 953, "end_pos": 955 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM03-1", "uniprot_ac": "A0A8V1AM03", "uniprot_id": "A0A8V1AM03_CHICK", "mass": { "chemical_mass": 89451.0, "monoisotopic_mass": 89451.0 }, "refseq": {}, "gene_names": [ { "name": "TRPV2", "type": "recommended", "evidence": [ { "id": "A0A8V1AM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ] } ], "protein_names": [ { "name": "Transient receptor potential cation channel subfamily V member 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRPV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03", "locus": { "chromosome": "19", "start_pos": 7088838, "end_pos": 7076460, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029738", "url": "https://www.ensembl.org/id/ENSGALG00010029738" } ] } } ], "crossref": [ { "id": "A0A8V1AM03", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004519", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417603", "url": "https://www.ncbi.nlm.nih.gov/gene/417603", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10582:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10582:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2UBT8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UBT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNFTNDQSGPCQRNRLVGLLETDDSIQEDKPTSSTKEERSGQYGKKGEPRPLESPYQKESSDYSPKVMINLNYRPGFVSNQKDPNRFDRDRLFSAVSRGSPEALDGLLEYLRRTSKFLTNSEYTDAKTGKTCLMKALLNLKNGRNDTIPVLLEIDQKTQNPRPLVNVACSDCYYRGQTALHIAIEKRSLDLVKVLVEHGADVHARAHGEFFRKKKEGVCFYFGELPLSLAACTNQFEVVEYLLNNPHQKARLQEQDTQGNTVLHALVMIADDTEENTKFVSTVYVEILKAGVKTDPTVKLEEIVNYDGLNPLQLAAKTGKVEIFRHIIQREIKDPVYRHLSRKFTEWTYGPIHVSLYDLSSLDSFEENSVLEILAYSSDTPNRYKMVVLEPLNKLLQQKWETFASKRFYFSFISYLSFMIIFTAIAYYQPLRPSFPVEFTAGGFLWVSGLIIILLGGVYLIFAQSLYLRRRRQSLKTMCSDSCVEILIFIQAFSLLLSAVLYGASSENYVAVMVFSLLLGWVNMLYYTRGFQRIGIYSVMIQKTILRDLLRFLLVYIIFLFGFAAALVTLMGDAPSLSQNKSVAQMENAGSHAMYGGLLSVCLELFKITIGMGDLDFHEHARFRYFVMLLLLLFVILTYILLLNMLIALMSETVTDISGYSKSVWKLQRAIAILEIEKAWLWRQGGKRRSGCLMSVGLNKKDERWCFRVEEIKWTSWAKEVGVLKEEPGNTNDLEINPEEMRSRKQVPQKQLRSAVSEEQSLLQPELSATEMMPLKGQTRNL", "length": 783, "header": "tr|A0A8V1AM03-1|A0A8V1AM03_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 2 OS=Gallus gallus OX=9031 GN=TRPV2 PE=1 SV=1 CANONICAL=A0A8V1AM03-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03/entry#A0A3Q2UBT8-1", "sequence": { "sequence": "MDNFTNDQSGPCQRNRLVGLLETDDSIQEDKPTSSTKEERSGQYGKKGEPRPLESPYQKESSDYSPKVMINLNYRPGFVSNQKDPNRFDRDRLFSAVSRGSPEALDGLLEYLRRTSKFLTNSEYTDAKTGKTCLMKALLNLKNGRNDTIPVLLEIDQKTQNPRPLVNVACSDCYYRGQTALHIAIEKRSLDLVKVLVEHGADVHARAHGEFFRKKKEGVCFYFGELPLSLAACTNQFEVVEYLLNNPHQKARLQEQDTQGNTVLHALVMIADDTEENTKFVSTVYVEILKAGVKTDPTVKLEEIVNYDGLNPLQLAAKTGKVEIFRHIIQREIKDPVYRHLSRKFTEWTYGPIHVSLYDLSSLDSFEENSVLEILAYSSDTPNRYKMVVLEPLNKLLQQKWETFASKRFYFSFISYLSFMIIFTAIAYYQPLRVKPSFPVEFTAGGFLWVSGLIIILLGGVYLIFAQSLYLRRRRQSLKTMCSDSCVEILIFIQAFSLLLSAVLYGASSENYVAVMVFSLLLGWVNMLYYTRGFQRIGIYSVMIQKTILRDLLRFLLVYIIFLFGFAAALVTLMGDAPSLSQNKSVAQMENAGSHAMYGGLLSVCLELFKITIGMGDLDFHEHARFRYFVMLLLLLFVILTYILLLNMLIALMSETVTDISGYSKSVWKLQRAIAILEIEKAWLWRQGGKRRSGCLMSVGLNKKDERWCFRVEEIKWTSWAKEVGVLKEEPGNTNDLEINPEASC", "length": 745, "header": "tr|A0A3Q2UBT8-1|A0A3Q2UBT8_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily V member 2 OS=Gallus gallus OX=9031 GN=TRPV2 PE=1 SV=1 CANONICAL=A0A8V1AM03-1" }, "locus": { "chromosome": "19", "start_pos": 7086877, "end_pos": 7078487, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071943.1", "url": "https://www.ensembl.org/id/ENSGALT00010071943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044633.1", "url": "https://www.ensembl.org/id/ENSGALP00010044633.1" } ] } }, { "isoform_ac": "A0A8V1AKG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03/entry#A0A8V1AKG6-1", "sequence": { "sequence": "MDNFTNDQSGPCQRNRLVGLLETDDSIQEDKPTSSTKEERSGQYGKKGEPRPLESPYQKESSDYSPKVMINLNYRPGFVSNQKDPNRFDRDRLFSAVSRGSPEALDGLLEYLRRTSKFLTNSEYTDAKTGKTCLMKALLNLKNGRNDTIPVLLEIDQKTQNPRPLVNVACSDCYYRGQTALHIAIEKRSLDLVKVLVEHGADVHARAHGEFFRKKKEGVCFYFGELPLSLAACTNQFEVVEYLLNNPHQKARLQEQDTQGNTVLHALVMIADDTEENTKFVSTVYVEILKAGVKTDPTVKLEEIVNYDGLNPLQLAAKTGKVEIFRHIIQREIKDPVYRHLSRKFTEWTYGPIHVSLYDLSSLDSFEENSVLEILAYSSDTPNRYKMVVLEPLNKLLQQKWETFASKRFYFSFISYLSFMIIFTAIAYYQPLRVKPSFPVEFTAGGFLWVSGLIIILLGGVYLIFAQLHPGFLIAVVSSPVWRKFRKLCGSDGVLSASGMGEHAVLHSGLSAHWHLQCHDTEALVTLMGDAPSLSQNKSVAQMENAGSHAMYGGLLSVCLELFKITIGMGDLDFHEHARFRYFVMLLLLLFVILTYILLLNMLIALMSETVTDISGYSKSVWKLQRAIAILEIEKAWLWRQGGKRRSGCLMSVGLNKKDERWCFRVEEIKWTSWAKEVGVLKEEPGNTNDLEINPEEMRSRKQVPQKQLRSAVSEEQSLLQPELSATEMMPLKGQTRNL", "length": 739, "header": "tr|A0A8V1AKG6-1|A0A8V1AM03_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily V member 2 OS=Gallus gallus OX=9031 GN=TRPV2 PE=1 SV=1 CANONICAL=A0A8V1AM03-1" }, "locus": { "chromosome": "19", "start_pos": 7087042, "end_pos": 7078487, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071941.1", "url": "https://www.ensembl.org/id/ENSGALT00010071941.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044631.1", "url": "https://www.ensembl.org/id/ENSGALP00010044631.1" } ] } }, { "isoform_ac": "A0A8V1AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03/entry#A0A8V1AM03-1", "sequence": { "sequence": "MDNFTNDQSGPCQRNRLVGLLETDDSIQEDKPTSSTKEERSGQYGKKGEPRPLESPYQKESSDYSPKVMINLNYRPGFVSNQKDPNRFDRDRLFSAVSRGSPEALDGLLEYLRRTSKFLTNSEYTDAKTGKTCLMKALLNLKNGRNDTIPVLLEIDQKTQNPRPLVNVACSDCYYRGQTALHIAIEKRSLDLVKVLVEHGADVHARAHGEFFRKKKEGVCFYFGELPLSLAACTNQFEVVEYLLNNPHQKARLQEQDTQGNTVLHALVMIADDTEENTKFVSTVYVEILKAGVKTDPTVKLEEIVNYDGLNPLQLAAKTGKVEIFRHIIQREIKDPVYRHLSRKFTEWTYGPIHVSLYDLSSLDSFEENSVLEILAYSSDTPNRYKMVVLEPLNKLLQQKWETFASKRFYFSFISYLSFMIIFTAIAYYQPLRPSFPVEFTAGGFLWVSGLIIILLGGVYLIFAQSLYLRRRRQSLKTMCSDSCVEILIFIQAFSLLLSAVLYGASSENYVAVMVFSLLLGWVNMLYYTRGFQRIGIYSVMIQKTILRDLLRFLLVYIIFLFGFAAALVTLMGDAPSLSQNKSVAQMENAGSHAMYGGLLSVCLELFKITIGMGDLDFHEHARFRYFVMLLLLLFVILTYILLLNMLIALMSETVTDISGYSKSVWKLQRAIAILEIEKAWLWRQGGKRRSGCLMSVGLNKKDERWCFRVEEIKWTSWAKEVGVLKEEPGNTNDLEINPEEMRSRKQVPQKQLRSAVSEEQSLLQPELSATEMMPLKGQTRNL", "length": 783, "header": "tr|A0A8V1AM03-1|A0A8V1AM03_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 2 OS=Gallus gallus OX=9031 GN=TRPV2 PE=1 SV=1 CANONICAL=A0A8V1AM03-1" }, "locus": { "chromosome": "19", "start_pos": 7087042, "end_pos": 7078487, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071938.1", "url": "https://www.ensembl.org/id/ENSGALT00010071938.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044628.1", "url": "https://www.ensembl.org/id/ENSGALP00010044628.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" }, { "name": "growth cone membrane", "id": "GO:0032584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032584", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" }, { "name": "axonal growth cone", "id": "GO:0044295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044295", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of axon extension", "id": "GO:0045773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" }, { "name": "positive regulation of calcium ion import", "id": "GO:0090280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090280", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" }, { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM03" }, { "id": "PF23317", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcium channel YVC1-like C-terminal transmembrane", "eco_id": "ECO_0000259", "start_pos": 487, "end_pos": 679, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 581, "end_pos": 583 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AQ10-1", "uniprot_ac": "A0A8V1AQ10", "uniprot_id": "A0A8V1AQ10_CHICK", "mass": { "chemical_mass": 42690.0, "monoisotopic_mass": 42690.0 }, "refseq": { "ac": "XP_415851", "name": "cystinosin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415851" }, "gene_names": [ { "name": "CTNS", "type": "recommended", "evidence": [ { "id": "A0A8V1AQ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10" } ] }, { "name": "CTNS", "type": "synonym", "evidence": [ { "id": "XP_415851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415851" } ] } ], "protein_names": [ { "name": "Cystinosin, lysosomal cystine transporter", "type": "synonym", "evidence": [ { "id": "A0A8V1AQ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10/entry#names_and_taxonomy" } ] }, { "name": "cystinosin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415851.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415851" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTNS", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10", "locus": { "chromosome": "19", "start_pos": 7129207, "end_pos": 7137412, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029744", "url": "https://www.ensembl.org/id/ENSGALG00010029744" } ] } } ], "crossref": [ { "id": "A0A8V1AQ10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AQ10", "database": "AlphaFoldDB", "categories": [] }, { "id": "417606", "url": "https://www.ncbi.nlm.nih.gov/gene/417606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417606", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIDVIYT", "url": "https://omabrowser.org/oma/group/WIDVIYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF38", "url": "https://www.orthodb.org/?gene=A0A8V1AF38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKI1", "url": "https://www.orthodb.org/?gene=A0A8V1AKI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM16", "url": "https://www.orthodb.org/?gene=A0A8V1AM16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ10", "url": "https://www.orthodb.org/?gene=A0A8V1AQ10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13131:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13131:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5223345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9959399", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9959399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "66172", "url": "https://www.rhea-db.org/rhea/66172", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AF38", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHLCPPVLLLTLVLLVHCGQCSAVLAWAQRDGVIVLSVPEVVLLENGSSTNVTISLRAPLNDTLVITLNITHSSKHSTIVELPDEIQLPAGHTKAGFQVKADDVGQVTVYLYTSNSNLTGPRIQFQVIHSIIVKYVDEVIGWIYFLAWSISFYPQLFENWRRKSVVGLSFDFIALNLTGFIAYSVFNVGLFWIPLIKEEFLLHYPNGVNPVAINDVFFSLHAIALTLLTIIQCCIYERAGQKVSKTVVGLLALAWIFTFTTLFLAAAEEMTWLQFLFCFSYIKLAVTLIKYFPQAYMNFRRKSTVGWSIGNVLLDFVGGSFSLLQMFLQSYNNDEWKLIFGDPTKFGLGVFSIIFDIVFMVQHYCLYRRQGYEPCE", "length": 377, "header": "tr|A0A8V1AQ10-1|A0A8V1AQ10_CHICK Isoform 1 of Cystinosin, lysosomal cystine transporter OS=Gallus gallus OX=9031 GN=CTNS PE=1 SV=1 CANONICAL=A0A8V1AQ10-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10/entry#A0A8V1AF38-1", "sequence": { "sequence": "MRHLCPPVLLLTLVLLVHCGQCSAVLAWAQRDGVIVLSVPEVVLLENGSSTNVTISLSVVGLSFDFIALNLTGFIAYSVFNVGLFWIPLIKEEFLLHYPNGVNPVAINDVFFSLHAIALTLLTIIQCCIYERAGQKVSKTVVGLLALAWIFTFTTLFLAAAEEMTWLQFLFCFSYIKLAVTLIKYFPQAYMNFRRKSTVGWSIGNVLLDFVGGSFSLLQMFLQSYNNDEWKLIFGDPTKFGLGVFSIIFDIVFMVQHYCLYRRQGYEPCE", "length": 270, "header": "tr|A0A8V1AF38-1|A0A8V1AF38_CHICK Computationally mapped isoform of Cystinosin, lysosomal cystine transporter OS=Gallus gallus OX=9031 GN=CTNS PE=3 SV=1 CANONICAL=A0A8V1AQ10-1" }, "locus": { "chromosome": "19", "start_pos": 7136734, "end_pos": 7130380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071954.1", "url": "https://www.ensembl.org/id/ENSGALT00010071954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044644.1", "url": "https://www.ensembl.org/id/ENSGALP00010044644.1" } ] } }, { "isoform_ac": "A0A8V1AKI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10/entry#A0A8V1AKI1-1", "sequence": { "sequence": "MRHLCPPVLLLTLVLLVHCDGVIVLSVPEVVLLENGSSTNVTISLRAPLNDTLVITLNITHSSKHSTIVELPDEIQLPAGHTKAGFQVKADDVGQVTVYLYTSNSNLTGPRIQFQVIHSIIVKYVDEVIGWIYFLAWSISFYPQLFENWRRKSVVGLSFDFIALNLTGFIAYSVFNVGLFWIPLIKEEFLLHYPNGVNPVAINDVFFSLHAIALTLLTIIQCCIYERAGQKVSKTVVGLLALAWIFTFTTLFLAAAEEMTWLQFLFCFSYIKLAVTLIKYFPQAYMNFRRKSTVGWSIGNVLLDFVGGSFSLLQMFLQSYNNDEWKLIFGDPTKFGLGVFSIIFDIVFMVQHYCLYRRQGYEPCE", "length": 365, "header": "tr|A0A8V1AKI1-1|A0A8V1AQ10_CHICK Computationally mapped isoform of Cystinosin, lysosomal cystine transporter OS=Gallus gallus OX=9031 GN=CTNS PE=1 SV=1 CANONICAL=A0A8V1AQ10-1" }, "locus": { "chromosome": "19", "start_pos": 7136734, "end_pos": 7130380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071956.1", "url": "https://www.ensembl.org/id/ENSGALT00010071956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044646.1", "url": "https://www.ensembl.org/id/ENSGALP00010044646.1" } ] } }, { "isoform_ac": "A0A8V1AM16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10/entry#A0A8V1AM16-1", "sequence": { "sequence": "MIFIRLAELSKSVVGLSFDFIALNLTGFIAYSVFNVGLFWIPLIKEEFLLHYPNGVNPVAINDVFFSLHAIALTLLTIIQCCIYERAGQKVSKTVVGLLALAWIFTFTTLFLAAAEEMTWLQFLFCFSYIKLAVTLIKYFPQAYMNFRRKSTVGWSIGNVLLDFVGGSFSLLQMFLQSYNNDEWKLIFGDPTKFGLGVFSIIFDIVFMVQHYCLYRRQGYEPCE", "length": 224, "header": "tr|A0A8V1AM16-1|A0A8V1AM16_CHICK Computationally mapped isoform of Cystinosin, lysosomal cystine transporter OS=Gallus gallus OX=9031 GN=CTNS PE=3 SV=1 CANONICAL=A0A8V1AQ10-1" }, "locus": { "chromosome": "19", "start_pos": 7133081, "end_pos": 7130380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071953.1", "url": "https://www.ensembl.org/id/ENSGALT00010071953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044643.1", "url": "https://www.ensembl.org/id/ENSGALP00010044643.1" } ] } }, { "isoform_ac": "A0A8V1AQ10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ10/entry#A0A8V1AQ10-1", "sequence": { "sequence": "MRHLCPPVLLLTLVLLVHCGQCSAVLAWAQRDGVIVLSVPEVVLLENGSSTNVTISLRAPLNDTLVITLNITHSSKHSTIVELPDEIQLPAGHTKAGFQVKADDVGQVTVYLYTSNSNLTGPRIQFQVIHSIIVKYVDEVIGWIYFLAWSISFYPQLFENWRRKSVVGLSFDFIALNLTGFIAYSVFNVGLFWIPLIKEEFLLHYPNGVNPVAINDVFFSLHAIALTLLTIIQCCIYERAGQKVSKTVVGLLALAWIFTFTTLFLAAAEEMTWLQFLFCFSYIKLAVTLIKYFPQAYMNFRRKSTVGWSIGNVLLDFVGGSFSLLQMFLQSYNNDEWKLIFGDPTKFGLGVFSIIFDIVFMVQHYCLYRRQGYEPCE", "length": 377, "header": "tr|A0A8V1AQ10-1|A0A8V1AQ10_CHICK Isoform 1 of Cystinosin, lysosomal cystine transporter OS=Gallus gallus OX=9031 GN=CTNS PE=1 SV=1 CANONICAL=A0A8V1AQ10-1" }, "locus": { "chromosome": "19", "start_pos": 7136734, "end_pos": 7130380, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071955.1", "url": "https://www.ensembl.org/id/ENSGALT00010071955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044645.1", "url": "https://www.ensembl.org/id/ENSGALP00010044645.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417606", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417606", "resource": "KEGG Pathway" }, { "id": "R-GGA-5223345", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "resource": "Reactome", "description": "Miscellaneous transport and binding events" }, { "id": "R-GGA-9959399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9959399", "resource": "Reactome", "description": "SLC-mediated transport of oligopeptides" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A9R9-1", "protein_name": "Cystinosin", "gene_name": "CTNS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIRKWLVIFILSPLKLIEKCESAVDFTVPPSVKLENGSSTSVSISLPRPLNATLVITFEITFRSKNVTILQLPDEVVVPPGVTNSSFQVTSQNVGQVTVYLHGNHSNQTSPRILFSVIHSHILSIINQVIGWIYFVAWSISFYPQVITNWRRKSVVGLSFDFVALNLMGFVAYSVFNIGLLWVPYIKEQFLLKYPNGVNPVVSNDVFFSLHAVALTLVVLVQCCLYERGNQRVSWPAISFLVLSWLFTLTALIVAAVGSITWLQFLFCFSYIKLAVTLIKYFPQAYMNFHYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGIFSIIFDIVFFIQHFCLYRKKPGYEQLN", "length": 367 }, "evidence": [ { "id": "A0A8V1AQ10", "url": "https://omabrowser.org/oma/group/A0A8V1AQ10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LND5-1", "protein_name": "Cystinosin", "gene_name": "Ctns", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGCFAEALGWGWNSLSNQVKLSVRLHFCGMSSLKSGNMMKNWLLILTLFLLKFIERSESTVGLSAPPTVKLVNGSSTNVSITLGHPLNSTLVITFEITFSSKNLTIVELPDEVIVPRGEKNASFQVTSQNIGQVTVYLHGNHSNQTCPRIQFLVIHSRIVSVINQVIGWIYFMAWSVSFYPQVIQNWRRKSVVGLSFDFLALNLTGFVAYSVFNIGLLWVPYIQEEFLLKYPNGVNPVDINDAFFSLHAVALTLIVILQCCLYERGNQRVSRPSIGFLVLAWLFILVTMIVAAVGVTTWLQFLFCFSYIKLIITLIKYFPQAYMNFYYKSTKGWSIGGVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGVFTIFFDIVFFIQHFYLYRKKPGLQAAPTGFDSHPSQN", "length": 415 }, "evidence": [ { "id": "A0A8V1AQ10", "url": "https://omabrowser.org/oma/group/A0A8V1AQ10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7MB63-1", "protein_name": "Cystinosin", "gene_name": "CTNS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIRRWLVIFILFPLQLIEKCESTVDFSVPPIVKLEKGSSTSVSISLPRPLNATLVITFEITFRSKNVTILQLPDEVVVPPGTTNSSFRVTSQSVGQVTTYLHGNHSNQTSPRIRFLVIHSNIVSIINQVIGWIYFVAWSVSFYPQVITNWRRKSVVGLSFDFVVLNLMGFVAYSVFNIGLFWVPSIKEQFLLKYPNGVNPVDSNDVFFSLHAVALTLVVIVQCLLYERGSQRVSWLAISFLVLSWLFTLIALIMAAVGATTWLQFLFCFSYIKLAVTLVKYFPQAYMNFHYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGIFSIIFDVVFFIQHFCLYRKKPGYDQLN", "length": 367 }, "evidence": [ { "id": "A0A8V1AQ10", "url": "https://omabrowser.org/oma/group/A0A8V1AQ10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O60931-1", "protein_name": "Cystinosin", "gene_name": "CTNS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIRNWLTIFILFPLKLVEKCESSVSLTVPPVVKLENGSSTNVSLTLRPPLNATLVITFEITFRSKNITILELPDEVVVPPGVTNSSFQVTSQNVGQLTVYLHGNHSNQTGPRIRFLVIRSSAISIINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVAYSVFNIGLLWVPYIKEQFLLKYPNGVNPVNSNDVFFSLHAVVLTLIIIVQCCLYERGGQRVSWPAIGFLVLAWLFAFVTMIVAAVGVTTWLQFLFCFSYIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGLGVFSIVFDVVFFIQHFCLYRKRPGYDQLN", "length": 367 }, "evidence": [ { "id": "A0A8V1AQ10", "url": "https://omabrowser.org/oma/group/A0A8V1AQ10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P57757-1", "protein_name": "Cystinosin", "gene_name": "Ctns", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997754.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997754" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRPV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1", "locus": { "chromosome": "19", "start_pos": 7186603, "end_pos": 7167647, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029747", "url": "https://www.ensembl.org/id/ENSGALG00010029747" } ] } } ], "crossref": [ { "id": "A0A8V1ANN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22194", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10582:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024997754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AF48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIKDNKEVVPLMGKKTNPPGAPPSNQQEKKPTESTPTKKSSHFFLEIEGFESNATPNNTSPPVFSKPMDSNIRPCASANGEDMDSPQSLQDDVTEYSPNVDSCGANIAQGPEQTGARKKLKKYIFRAVSEGNVEELQGLLAELKERSNVCTNMTVPDYLMKKFTASDTGKTCLMKALLNINNNTNQIVNMLLSFAEENGILERFINAAYTEEAYRGQTALNIAIERRQFEITQSLIEKGADVNAHAQGIFFNPKHKHEGFYFGETALALAACTNQPDIIELLMDNTRTNIAAQDSRGNNILHALVTVAEDFKTQNDFVIRMYDMILLKSKDRNLEKVKNKEGLTPLQLAAKTGKLEVLKYILSREIRDKPNRSLSRKFTDWAYGPVQSSLYDLTELDTTADNSVLEIIVYNTNIGNRHEMLTLEPLNSLLRMKWKRFARHMLFMSCCFYFLYNVTLTLVSYHRPNENEAPPYPLALTRGVGWLQLSGQVMVMLGAIFLAIKESVAIFLLRPSDLQSILSDAWFHFAFFIQAMLVIFSVFLYLSSYKEHLVCLVLAMALGWANMLYFTRGFQSMGIYSVMIQKVILNDVIKFLVVYIVFLLGFGVALAALIETCQNGGECLSNSSLGPVLMDLFKLTLGLGDLEIQQNSKYPVLFLLLLITYVVLTFVLLLNMLIALMGETVEDISKESEHIWKLQRARTILEFEKFLPKSLRKKFQLGERCKVAENDTRVCLRINEVRWTEWKTHVSFINEDPGPTDPSKVQDNSRTNSKNTLNTFEETDDLPETSL", "length": 787, "header": "tr|A0A8V1ANN1-1|A0A8V1ANN1_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 3 OS=Gallus gallus OX=9031 GN=TRPV3 PE=4 SV=1 CANONICAL=A0A8V1ANN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AF48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1/entry#A0A8V1AF48-1", "sequence": { "sequence": "MIKDNKEVVPLMGKKTNPPGAPPSNQQEKKPTESTPTKKSSHFFLEIEGFESNATPNNTSPPVFSKPMDSNIRPCASANGEDMDSPQSLQDDVTEYSPNVDSCGANIAQGPEQTGARKKLKKYIFRAVSEGNVEELQGLLAELKERSNVCTNMTVPDYLMKKFTASDTGKTCLMKALLNINNNTNQIVNMLLSFAEENGILERFINAAYTEEAYRGQTALNIAIERRQFEITQSLIEKGADVNAHAQGIFFNPKHKHEGFYFGETALALAACTNQPDIIELLMDNTRTNIAAQDSRGNNILHALVTVAEDFKTQNDFVIRMYDMILLKSKDRNLEKVKNKEGLTPLQLAAKTGKLEVLKYILSREIRDKPNRSLSRKFTDWAYGPVQSSLYDLTELDTTADNSVLEIIVYNTNIGNRHEMLTLEPLNSLLRMKWKRFARHMLFMSCCFYFLYNVTLTLVSYHRPNENEAPPYPLALTRGVGWLQLSGQVMVMLGAIFLAIKESVAIFLLRPSDLQSILSDAWFHFAFFIQAMLVIFSVFLYLSSYKEHLVCLVLAMALGWANMLYFTRGFQSMGIYSVMIQKVILNDVIKFLVVYIVFLLGFGVALAALIETCQNGGECLSNSSLGPVLMDLFKLTLGLGDLEIQQNSKYPVLFLLLLITYVVLTFVLLLNMLIALMGETVEDISKESEHIWKLQRARTILEFEKFLPKSLRKKFQLGERCKVAENDTRVCLRINEVRWTEWKTHVSFINEDPGPTAKPEVRKLTPKTFLTQKRA", "length": 775, "header": "tr|A0A8V1AF48-1|A0A8V1AF48_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily V member 3 OS=Gallus gallus OX=9031 GN=TRPV3 PE=4 SV=1 CANONICAL=A0A8V1ANN1-1" }, "locus": { "chromosome": "19", "start_pos": 7185815, "end_pos": 7171022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071964.1", "url": "https://www.ensembl.org/id/ENSGALT00010071964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044654.1", "url": "https://www.ensembl.org/id/ENSGALP00010044654.1" } ] } }, { "isoform_ac": "A0A8V1AKI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1/entry#A0A8V1AKI7-1", "sequence": { "sequence": "MALGWANMLYFTRGFQSMGIYSVMIQKVILNDVIKFLVVYIVFLLGFGVALAALIETCQNGGECLSNSSLGPVLMDLFKLTLGLGDLEIQQNSKYPVLFLLLLITYVVLTFVLLLNMLIALMGETVEDISKESEHIWKLQRARTILEFEKFLPKSLRKKFQLGERCKVAENDTRVCLRINEVRWTEWKTHVSFINEDPGPTAKPEVRKLTPKTFLTQKRA", "length": 220, "header": "tr|A0A8V1AKI7-1|A0A8V1ANN1_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily V member 3 OS=Gallus gallus OX=9031 GN=TRPV3 PE=4 SV=1 CANONICAL=A0A8V1ANN1-1" }, "locus": { "chromosome": "19", "start_pos": 7185815, "end_pos": 7180970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071961.1", "url": "https://www.ensembl.org/id/ENSGALT00010071961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044651.1", "url": "https://www.ensembl.org/id/ENSGALP00010044651.1" } ] } }, { "isoform_ac": "A0A8V1ANN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1/entry#A0A8V1ANN1-1", "sequence": { "sequence": "MIKDNKEVVPLMGKKTNPPGAPPSNQQEKKPTESTPTKKSSHFFLEIEGFESNATPNNTSPPVFSKPMDSNIRPCASANGEDMDSPQSLQDDVTEYSPNVDSCGANIAQGPEQTGARKKLKKYIFRAVSEGNVEELQGLLAELKERSNVCTNMTVPDYLMKKFTASDTGKTCLMKALLNINNNTNQIVNMLLSFAEENGILERFINAAYTEEAYRGQTALNIAIERRQFEITQSLIEKGADVNAHAQGIFFNPKHKHEGFYFGETALALAACTNQPDIIELLMDNTRTNIAAQDSRGNNILHALVTVAEDFKTQNDFVIRMYDMILLKSKDRNLEKVKNKEGLTPLQLAAKTGKLEVLKYILSREIRDKPNRSLSRKFTDWAYGPVQSSLYDLTELDTTADNSVLEIIVYNTNIGNRHEMLTLEPLNSLLRMKWKRFARHMLFMSCCFYFLYNVTLTLVSYHRPNENEAPPYPLALTRGVGWLQLSGQVMVMLGAIFLAIKESVAIFLLRPSDLQSILSDAWFHFAFFIQAMLVIFSVFLYLSSYKEHLVCLVLAMALGWANMLYFTRGFQSMGIYSVMIQKVILNDVIKFLVVYIVFLLGFGVALAALIETCQNGGECLSNSSLGPVLMDLFKLTLGLGDLEIQQNSKYPVLFLLLLITYVVLTFVLLLNMLIALMGETVEDISKESEHIWKLQRARTILEFEKFLPKSLRKKFQLGERCKVAENDTRVCLRINEVRWTEWKTHVSFINEDPGPTDPSKVQDNSRTNSKNTLNTFEETDDLPETSL", "length": 787, "header": "tr|A0A8V1ANN1-1|A0A8V1ANN1_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 3 OS=Gallus gallus OX=9031 GN=TRPV3 PE=4 SV=1 CANONICAL=A0A8V1ANN1-1" }, "locus": { "chromosome": "19", "start_pos": 7184550, "end_pos": 7171022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071962.1", "url": "https://www.ensembl.org/id/ENSGALT00010071962.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044652.1", "url": "https://www.ensembl.org/id/ENSGALP00010044652.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 756, "start_aa": "Thr", "end_pos": 756, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr756", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:771945", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771945", "resource": "KEGG Pathway" }, { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "E9PU00-1", "protein_name": "Transient receptor potential cation channel subfamily V member 3", "gene_name": "Trpv3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAHSKEMVPLMGKRTTAPGGNPAVLTEKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTSPPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLKKCIFAAVSEGCVRELRELLQDLQELCRRRRGLDASDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILGREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEIIVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPREDEALPHPLALTHKMSWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTADSNKIQDSSRSNSKTTLYAFDELDEFPETSV", "length": 791 }, "evidence": [ { "id": "A0A8V1ANN1", "url": "https://omabrowser.org/oma/group/A0A8V1ANN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K424-1", "protein_name": "Transient receptor potential cation channel subfamily V member 3", "gene_name": "Trpv3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAHSKEMAPLMGKRTTAPGGNPVVLTEKRPADLTPTKKSAHFFLEIEGFEPNPTVTKTSPPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVTETPSNPNSPSANLAKEEQRQKKKRLKKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEIIVYNTNIDNRHEMLTLEPLHTLLHTKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPREDEDLPHPLALTHKMSWLQLLGRMFVLIWATCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTADLNKIQDSSRSNSKTTLYAFDELDEFPETSV", "length": 791 }, "evidence": [ { "id": "A0A8V1ANN1", "url": "https://omabrowser.org/oma/group/A0A8V1ANN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NET8-1", "protein_name": "Transient receptor potential cation channel subfamily V member 3", "gene_name": "TRPV3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKAHPKEMVPLMGKRVAAPSGNPAILPEKRPAEITPTKKSAHFFLEIEGFEPNPTVAKTSPPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVTETPSNPNSPSAQLAKEEQRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTDFNKIQDSSRNNSKTTLNAFEEVEEFPETSV", "length": 790 }, "evidence": [ { "id": "A0A8V1ANN1", "url": "https://omabrowser.org/oma/group/A0A8V1ANN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "monoatomic ion channel activity", "id": "GO:0005216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "osmosensory signaling pathway", "id": "GO:0007231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007231", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" }, { "name": "calcium ion import across plasma membrane", "id": "GO:0098703", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098703", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN1" }, { "id": "PF23317", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcium channel YVC1-like C-terminal transmembrane", "eco_id": "ECO_0000259", "start_pos": 523, "end_pos": 703, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 756 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 726, "end_pos": 728 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMG4-1", "uniprot_ac": "A0A8V1AMG4", "uniprot_id": "A0A8V1AMG4_CHICK", "mass": { "chemical_mass": 32194.0, "monoisotopic_mass": 32194.0 }, "refseq": {}, "gene_names": [ { "name": "WBSCR22", "type": "recommended", "evidence": [ { "id": "A0A8V1AMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ] } ], "protein_names": [ { "name": "18S rRNA (guanine-N(7))-methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V1AMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4/entry#names_and_taxonomy" } ] }, { "name": "Bud site selection protein 23 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V1AMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4/entry#names_and_taxonomy" } ] }, { "name": "rRNA methyltransferase and ribosome maturation factor", "type": "synonym", "evidence": [ { "id": "A0A8V1AMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Locus-specific steroid receptor coactivator. Potentiates transactivation by glucocorticoid (NR3C1), mineralocorticoid (NR3C2), androgen (AR) and progesterone (PGR) receptors. Required for the maintenance of open chromatin at the TSC22D3/GILZ locus to facilitate NR3C1 loading on the response elements. Required for maintenance of dimethylation on histone H3 'Lys-79' (H3K79me2), although direct histone methyltransferase activity is not observed in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4#function" }, { "database": "UniProtKB", "id": "ARBA00059355", "url": "https://www.uniprot.org/uniprotkb/ARBA00059355#function" }, { "database": "UniProtKB", "id": "A0A8V1AKJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ5#function" }, { "database": "UniProtKB", "id": "A0A8V1ADC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WBSCR22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4", "locus": { "chromosome": "19", "start_pos": 624163, "end_pos": 618754, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029513", "url": "https://www.ensembl.org/id/ENSGALG00010029513" } ] } } ], "crossref": [ { "id": "A0A8V1AMG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431053", "url": "https://www.ncbi.nlm.nih.gov/gene/431053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022238", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022238", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431053", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIQEKKE", "url": "https://omabrowser.org/oma/group/WIQEKKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ADC2", "url": "https://www.orthodb.org/?gene=A0A8V1ADC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKJ5", "url": "https://www.orthodb.org/?gene=A0A8V1AKJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMG4", "url": "https://www.orthodb.org/?gene=A0A8V1AMG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12734", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12734", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12734:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12734:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13649", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13649", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "54584", "url": "https://www.rhea-db.org/rhea/54584", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ADC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ADC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSGRRPEHRGPPELFYDETEARKYTQNSRVAEIQAQMAARAVELLALPEGRPCLLLDVGCGSGLSGEHISEEGHCWIGVDISRAMLDVAVEREVEGDLLLADMGDGIPFRPGTFDGCIRRCTFSISAVQWLCNADKKSHSPPKRLYWFFSTLYTALARGSRAVLQLYPENSEQLELITAQAMRAGFTGGMVIDYPNSAKAKKFFLCLFVGASGTLPKGLGTECADGEEIHQAKFTQERIRFRNAKGKSVKKSRDWILEKKERRRRQGKEVRADTKYTGRKRRPQF", "length": 287, "header": "tr|A0A8V1AMG4-1|A0A8V1AMG4_CHICK Isoform 1 of 18S rRNA (guanine-N(7))-methyltransferase OS=Gallus gallus OX=9031 GN=WBSCR22 PE=3 SV=1 CANONICAL=A0A8V1AMG4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ADC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4/entry#A0A8V1ADC2-1", "sequence": { "sequence": "MASSGRRPEHRGPPELFYDETEARKYTQNSRVAEIQAQMAARAVELLALPEGRPCLLLDVGCGSGLSGEHISEEGHCWIGVDISRAMLDVAVEREVEGDLLLADMGDGIPFRPGTFDGCISISAVQWLCNADKKSHSPPKRLYWFFSTLYTALARGSRAVLQLYPENSEQLELITAQAMRAGFTVLYLCVWACGLGTECADGEEIHQAKFTQERIRFRNAKGKSVKKSRDWILEKKERRRRQGKEVRADTKYTGRKRRPQF", "length": 261, "header": "tr|A0A8V1ADC2-1|A0A8V1ADC2_CHICK Computationally mapped isoform of 18S rRNA (guanine-N(7))-methyltransferase OS=Gallus gallus OX=9031 GN=WBSCR22 PE=3 SV=1 CANONICAL=A0A8V1AMG4-1" }, "locus": { "chromosome": "19", "start_pos": 623231, "end_pos": 618764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071338.1", "url": "https://www.ensembl.org/id/ENSGALT00010071338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044029.1", "url": "https://www.ensembl.org/id/ENSGALP00010044029.1" } ] } }, { "isoform_ac": "A0A8V1AKJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4/entry#A0A8V1AKJ5-1", "sequence": { "sequence": "MASSGRRPEHRGPPELFYDETEARKYTQNSRVAEIQAQMAARAVELLALPEGRPCLLLDVGCGSGLSGEHISEEGHCWIGVDISRAMLDVAVEREVEGDLLLADMGDGIPFRPGTFDGCISISAVQWLCNADKKSHSPPKRLYWFFSTLYTALARGSRAVLQLYPENSEQLELITAQAMRAGFTGGMVIDYPNSAKAKKFFLCLFVGASGTLPKGLGTECADGEEIHQAKFTQERIRFRNAKGKSVKKSRDWILEKKERRRRQGKEVRADTKYTGRKRRPQF", "length": 282, "header": "tr|A0A8V1AKJ5-1|A0A8V1AMG4_CHICK Computationally mapped isoform of 18S rRNA (guanine-N(7))-methyltransferase OS=Gallus gallus OX=9031 GN=WBSCR22 PE=3 SV=1 CANONICAL=A0A8V1AMG4-1" }, "locus": { "chromosome": "19", "start_pos": 623231, "end_pos": 618764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071337.1", "url": "https://www.ensembl.org/id/ENSGALT00010071337.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044028.1", "url": "https://www.ensembl.org/id/ENSGALP00010044028.1" } ] } }, { "isoform_ac": "A0A8V1AMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4/entry#A0A8V1AMG4-1", "sequence": { "sequence": "MASSGRRPEHRGPPELFYDETEARKYTQNSRVAEIQAQMAARAVELLALPEGRPCLLLDVGCGSGLSGEHISEEGHCWIGVDISRAMLDVAVEREVEGDLLLADMGDGIPFRPGTFDGCIRRCTFSISAVQWLCNADKKSHSPPKRLYWFFSTLYTALARGSRAVLQLYPENSEQLELITAQAMRAGFTGGMVIDYPNSAKAKKFFLCLFVGASGTLPKGLGTECADGEEIHQAKFTQERIRFRNAKGKSVKKSRDWILEKKERRRRQGKEVRADTKYTGRKRRPQF", "length": 287, "header": "tr|A0A8V1AMG4-1|A0A8V1AMG4_CHICK Isoform 1 of 18S rRNA (guanine-N(7))-methyltransferase OS=Gallus gallus OX=9031 GN=WBSCR22 PE=3 SV=1 CANONICAL=A0A8V1AMG4-1" }, "locus": { "chromosome": "19", "start_pos": 623231, "end_pos": 618764, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071336.1", "url": "https://www.ensembl.org/id/ENSGALT00010071336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044027.1", "url": "https://www.ensembl.org/id/ENSGALP00010044027.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431053", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M7W3-1", "protein_name": "18S rRNA (guanine-N(7))-methyltransferase", "gene_name": "Bud23", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASRSRRPEHSGPPELFYDQNEARKYVRNSRMIDIQTKMTERALELLCLPEGQPSFLLDIGCGSGLSGDYISEEGHYWVGIDISPAMLDAALDRDTEGDLLLGDMGQGIPFRPGSFDGCISISAVQWLCNANKKSDVPARRLYCFFSSLYSALVHGARAVLQLYPENSEQLELITTQATRAGFTGGVVVDFPNSAKAKKFYLCLFSGPSTSLPKGLTESQDADQATELTFTSERAPHKKARRDLVKKSREWVLEKKERRRRQGKEVRPDTQYTGRKRKPRF", "length": 281 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O43709-1", "protein_name": "18S rRNA (guanine-N(7))-methyltransferase", "gene_name": "BUD23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF", "length": 281 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P25627-1", "protein_name": "18S rRNA (guanine(1575)-N(7))-methyltransferase", "gene_name": "BUD23", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRPEELAPPEIFYNDSEAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGIPFRAGSFDAAISISAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLVVDDPESKKNKKYYLVLSSGAPPQGEEQVNLDGVTMDEENVNLKKQLRQRLKGGKDKESAKSFILRKKELMKRRGRKVAKDSKFTGRKRRHRF", "length": 275 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55DA6-1", "protein_name": "Probable 18S rRNA (guanine-N(7))-methyltransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSRPEHIAPPEIFYDDVESKKYSSNSRIIEIQTKMAERAYELLAIPETAEGLMLLDIGCGSGISGDVITDAGHYWIGCDISQHMLDVAIDREVEGDVMLRDIGQGFPFRAGSFDAAISISAIQWLCNAEKSHHNPRKRLHTFFQSLFNVLTRGGKAILQFYPENSAQIEMITASALRCGFSGGLLIDFPNSSKAKKYFLVLFTGNNNIMPSAKGVEGEEYEQQEEEDSNEVKYSNRKRDRRRVTKSKGSAQHKTKEWIMNKKDRQRKQGREIKNDSKFSGRKRGPKF", "length": 287 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q58DP0-1", "protein_name": "18S rRNA (guanine-N(7))-methyltransferase", "gene_name": "BUD23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFRGRRPELRGPPELYYDKNEARKYVRNSRMIDVQIKMTGRALELLCVPEDKPCYVLDIGCGTGLSGDYLSDEGHYWVGIDISPAMLDEALDRETQGDVILGDMGQGIPFKPGTFDACISISAVQWLCNANKKSDIPAKRLYCFFSSLYSVLVRGGRAVLQLYPENSEQLELITTQATRAGFTGGVVVDYPNSAKAKKFYLCLFSGPSTSLPEGLSEDTEEEKPAESTFTADRIPYRIARRGVVRKSREWVLEKKARRRRQGKEVCPDTQYTGRKRKPRF", "length": 281 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CY21-1", "protein_name": "18S rRNA (guanine-N(7))-methyltransferase", "gene_name": "Bud23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRSRRPEHSGPPELFYDQNEARKYVRNSRMIDIQTKMTERALELLCLPEGQPSYLLDIGCGSGLSGDYISEEGHYWVGIDISPAMLDAALDRDTEGDLLLGDMGQGVPFRPGSFDGCISISAVQWLCNANKKSDVPARRLYCFFSSLYSALVRGARAVLQLYPENSEQLELITTQATRAGFTGGVVVDFPNSAKAKKFYLCLFSGPSTSLPKGLTESQDADQASESMFTSERAPHKKARRDLVKKSREWVLEKKERRRRQGKEVRPDTQYTGRKRKPRF", "length": 281 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LVD0-1", "protein_name": "18S rRNA (guanine-N(7))-methyltransferase RID2", "gene_name": "RID2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSNRPELLAPPEIFYDDTEARKYTSSSRIVEIQAKLSERALELLALPEDGVPRFLLDIGCGSGLSGETLSEDGHHWIGLDISASMLHVAVEREVEGDLLLGDMGQGLGLRSGVIDGAISISAVQWLCNADKSSHEPRLRLKAFFGSLYRCLSRGARAVFQVYPENIAQRELILRQALQAGFGGGLVVDYPHSTKKRKEFLVLTCGTVQTSIQTSKNEYDESCSEDDNSDDEESEEVGVSDRNRPRKRQRTNTKVKGREWVLRKKEQSRRKGKNVPADSKFTSRKRRTRF", "length": 289 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VHW6-1", "protein_name": "18S rRNA (guanine-N(7))-methyltransferase", "gene_name": "Dmel\\CG10903", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARRPEHSAPPEIFYNDDEAKKYSTNTRIIEIQVEMAERALELLALPDDDESRLILDIGCGSGLSGSVLEDSEHMWIGIDISKSMLDIAVEREVAGDVILGDMGEGMPFKPGTFDGAISISALQWLCNADKSYHNPHKRLLKFFTTLFSCLTRTARAVFQFYPENSDQIEMVTSQAMKAGFYGGLVVDYPNSAKAKKYYLVLMTGGSAELPQALGSPEEERRVNYIKKRDACREARGKAPKKSRDWILAKKERRRRQGLETRPDTKYTARKRSGKF", "length": 276 }, "evidence": [ { "id": "A0A8V1AMG4", "url": "https://omabrowser.org/oma/group/A0A8V1AMG4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA (guanine) methyltransferase activity", "id": "GO:0016435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA (guanine-N7)-methylation", "id": "GO:0070476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070476", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" }, { "name": "positive regulation of rRNA processing", "id": "GO:2000234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000234", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54584", "name": "", "equation": "a guanosine in 18S rRNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in 18S rRNA + S-adenosyl-L-homocysteine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "54584", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54584" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" }, { "id": "PF12589", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12589" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 284, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AMG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG4" }, { "id": "PF13649", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13649" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 122, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM43-1", "uniprot_ac": "A0A8V1AM43", "uniprot_id": "A0A8V1AM43_CHICK", "mass": { "chemical_mass": 79627.0, "monoisotopic_mass": 79627.0 }, "refseq": {}, "gene_names": [ { "name": "AKAP10", "type": "recommended", "evidence": [ { "id": "A0A8V1AM43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ] } ], "protein_names": [ { "name": "A-kinase anchoring protein 10", "type": "synonym", "evidence": [ { "id": "A0A8V1AM43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKAP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43", "locus": { "chromosome": "19", "start_pos": 7277009, "end_pos": 7257238, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029753", "url": "https://www.ensembl.org/id/ENSGALG00010029753" } ] } } ], "crossref": [ { "id": "A0A8V1AM43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM43", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12804", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12804", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKK9", "url": "https://www.orthodb.org/?gene=A0A8V1AKK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM43", "url": "https://www.orthodb.org/?gene=A0A8V1AM43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANP7", "url": "https://www.orthodb.org/?gene=A0A8V1ANP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ22", "url": "https://www.orthodb.org/?gene=A0A8V1AQ22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13155:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13155:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AKK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ22", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQPGHAGTAAEMGTAAALPPTCTKAPGSQLCTNTRSSDAQTSTSTAQAQPYCWDCRRVSHSSALRSQCSQSSEKSTYEMESQHHANALKGKEQEKTTDVKAIKTPGPVHSPQRSTRNHALLEAAGPSHVAINAISANMDSFSSSRTAALKKQPSHMEAAHFGDLGRSCLNYQAQETKSSLSKTLEQVLQDSVALPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKQQEIAPSSPPGLLEERLEDASTVHLLRTRSVTPDKSDRTHNSRNHVLSAQERDDTSVLCLRKSETGTHSVPADHQESSKLTVSNRNSPSSALKDLSGKLMKSIERDAVSTFTKYISPDAAKPIPITEAMRNDIVAKICGEDGQVDPNCFVTAQSIVFNAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNVLQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDSVRLEIESNICREGGPLPNCFTTPLRQAWTTMETVFLPGFLSSNLYYKYLNDLIHSVRGDDFPGGNIALSIQGPGGSPDSDSIGGPDGSASQSNVKKANVKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVKKSKGSMFSQAMKKWVQGNTDEAQEEMAWRIAKMIVNDVMQQAHCEQRLEKGTKL", "length": 720, "header": "tr|A0A8V1AM43-1|A0A8V1AM43_CHICK Isoform 1 of A-kinase anchoring protein 10 OS=Gallus gallus OX=9031 GN=AKAP10 PE=4 SV=1 CANONICAL=A0A8V1AM43-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43/entry#A0A8V1AKK9-1", "sequence": { "sequence": "MSFFRRKGLTVKGKEQEKTTDVKAIKTPGPVHSPQRSTRNHALLEAAGPSHVAINAISANMDSFSSSRTAALKKQPSHMEAAHFGDLGRSCLNYQAQETKSSLSKTLEQVLQDSVALPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKQQEIAPSSPPGLLEERLEDASTVHLLRTRSVTPDKSDRTHNSRNHVLSAQERDDTSVLCLRKSETGTHSVPADHQESSKLTVSNRNSPSSALKDLSGKLMKSIERDAVSTFTKYISPDAAKPIPITEAMRNDIVAKICGEDGQVDPNCFVTAQSIVFNAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNVLQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDSVRLEIESNICREGGPLPNCFTTPLRQAWTTMETVFLPGFLSSNLYYKYLNDLIHSVRGDDFPGGNIALSIQGPGGSPDSDSIGGPDGSASQSNVKKANVKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVKKSKGSMFSQAMKKWVQGNTDEAQEEMAWRIAKMIVNDVMQQAHCEQRLEKGTKL", "length": 642, "header": "tr|A0A8V1AKK9-1|A0A8V1AM43_CHICK Computationally mapped isoform of A-kinase anchoring protein 10 OS=Gallus gallus OX=9031 GN=AKAP10 PE=4 SV=1 CANONICAL=A0A8V1AM43-1" }, "locus": { "chromosome": "19", "start_pos": 7275390, "end_pos": 7262335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071981.1", "url": "https://www.ensembl.org/id/ENSGALT00010071981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044671.1", "url": "https://www.ensembl.org/id/ENSGALP00010044671.1" } ] } }, { "isoform_ac": "A0A8V1AM43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43/entry#A0A8V1AM43-1", "sequence": { "sequence": "MRQPGHAGTAAEMGTAAALPPTCTKAPGSQLCTNTRSSDAQTSTSTAQAQPYCWDCRRVSHSSALRSQCSQSSEKSTYEMESQHHANALKGKEQEKTTDVKAIKTPGPVHSPQRSTRNHALLEAAGPSHVAINAISANMDSFSSSRTAALKKQPSHMEAAHFGDLGRSCLNYQAQETKSSLSKTLEQVLQDSVALPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKQQEIAPSSPPGLLEERLEDASTVHLLRTRSVTPDKSDRTHNSRNHVLSAQERDDTSVLCLRKSETGTHSVPADHQESSKLTVSNRNSPSSALKDLSGKLMKSIERDAVSTFTKYISPDAAKPIPITEAMRNDIVAKICGEDGQVDPNCFVTAQSIVFNAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNVLQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDSVRLEIESNICREGGPLPNCFTTPLRQAWTTMETVFLPGFLSSNLYYKYLNDLIHSVRGDDFPGGNIALSIQGPGGSPDSDSIGGPDGSASQSNVKKANVKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVKKSKGSMFSQAMKKWVQGNTDEAQEEMAWRIAKMIVNDVMQQAHCEQRLEKGTKL", "length": 720, "header": "tr|A0A8V1AM43-1|A0A8V1AM43_CHICK Isoform 1 of A-kinase anchoring protein 10 OS=Gallus gallus OX=9031 GN=AKAP10 PE=4 SV=1 CANONICAL=A0A8V1AM43-1" }, "locus": { "chromosome": "19", "start_pos": 7275390, "end_pos": 7257317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071983.1", "url": "https://www.ensembl.org/id/ENSGALT00010071983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044673.1", "url": "https://www.ensembl.org/id/ENSGALP00010044673.1" } ] } }, { "isoform_ac": "A0A8V1ANP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43/entry#A0A8V1ANP7-1", "sequence": { "sequence": "MESQHHANALKGKEQEKTTDVKAIKTPGPVHSPQRSTRNHALLEAAGPSHVAINAISANMDSFSSSRTAALKKQPSHMEAAHFGDLGRSCLNYQAQETKSSLSKTLEQVLQDSVALPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKQQEIAPSSPPGLLEERLEDASTVHLLRTRSVTPDKSDRTHNSRNHVLSAQERDDTSVLCLRKSETGTHSVPADHQESSKLTVSNRNSPSSALKDLSGKLMKSIERDAVSTFTKYISPDAAKPIPITEAMRNDIVAKICGEDGQVDPNCFVTAQSIVFNAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNVLQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDSVRLEIESNICREGGPLPNCFTTPLRQAWTTMETVFLPGFLSSNLYYKYLNDLIHSVRGDDFPGGNIALSIQGPGGSPDSDSIGGPDGSASQSNVKKANVKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVKKSKGSMFSQAMKKWVQGNTDEAQEEMAWRIAKMIVNDVMQQAHCEQRLEKGTKL", "length": 641, "header": "tr|A0A8V1ANP7-1|A0A8V1ANP7_CHICK Computationally mapped isoform of A-kinase anchoring protein 10 OS=Gallus gallus OX=9031 GN=AKAP10 PE=4 SV=1 CANONICAL=A0A8V1AM43-1" }, "locus": { "chromosome": "19", "start_pos": 7275390, "end_pos": 7260169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071982.1", "url": "https://www.ensembl.org/id/ENSGALT00010071982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044672.1", "url": "https://www.ensembl.org/id/ENSGALP00010044672.1" } ] } }, { "isoform_ac": "A0A8V1AQ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43/entry#A0A8V1AQ22-1", "sequence": { "sequence": "MKGKEQEKTTDVKAIKTPGPVHSPQRSTRNHALLEAAGPSHVAINAISANMDSFSSSRTAALKKQPSHMEAAHFGDLGRSCLNYQAQETKSSLSKTLEQVLQDSVALPYFIQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAEPVSPSKQQEIAPSSPPGLLEERLEDASTVHLLRTRSVTPDKSDRTHNSRNHVLSAQERDDTSVLCLRKSETGTHSVPADHQESSKLTVSNRNSPSSALKDLSGKLMKSIERDAVSTFTKYISPDAAKPIPITEAMRNDIVAKICGEDGQVDPNCFVTAQSIVFNAMEQEHFSEFLRSHHFCKYQIEVLTSGTVYLADILFCESALFYFSEYMEKEDAVNVLQFWLAADNFQSQLAAKKGQYDGQEAQNDAMILYDKYFSLQATHPLGFDDSVRLEIESNICREGGPLPNCFTTPLRQAWTTMETVFLPGFLSSNLYYKYLNDLIHSVRGDDFPGGNIALSIQGPGGSPDSDSIGGPDGSASQSNVKKANVKILKNFDEAIIVDAASLDPESLYQRTYAGKMTFGRVSDLGQFIRESEPEPDVKKSKGSMFSQAMKKWVQGNTDEAQEEMAWRIAKMIVNDVMQQAHCEQRLEKGTKL", "length": 632, "header": "tr|A0A8V1AQ22-1|A0A8V1AQ22_CHICK Computationally mapped isoform of A-kinase anchoring protein 10 OS=Gallus gallus OX=9031 GN=AKAP10 PE=4 SV=1 CANONICAL=A0A8V1AM43-1" }, "locus": { "chromosome": "19", "start_pos": 7275390, "end_pos": 7263529, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071980.1", "url": "https://www.ensembl.org/id/ENSGALT00010071980.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044670.1", "url": "https://www.ensembl.org/id/ENSGALP00010044670.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AM43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM43" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 427, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANQ8-1", "uniprot_ac": "A0A8V1ANQ8", "uniprot_id": "A0A8V1ANQ8_CHICK", "mass": { "chemical_mass": 44617.0, "monoisotopic_mass": 44617.0 }, "refseq": {}, "gene_names": [ { "name": "MRPL38", "type": "recommended", "evidence": [ { "id": "A0A8V1ANQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein mL38", "type": "recommended", "evidence": [ { "id": "A0A8V1ANQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L38, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8V1ANQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL38", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8", "locus": { "chromosome": "18", "start_pos": 5250051, "end_pos": 5245392, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029761", "url": "https://www.ensembl.org/id/ENSGALG00010029761" } ] } } ], "crossref": [ { "id": "A0A8V1ANQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR008914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKM3", "url": "https://www.orthodb.org/?gene=A0A8V1AKM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM58", "url": "https://www.orthodb.org/?gene=A0A8V1AM58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANQ8", "url": "https://www.orthodb.org/?gene=A0A8V1ANQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11362", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11362", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11362:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11362:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AKM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAAPLLSAALRGAWSGRAFGTAAALRKRAAPLGPMPNEDIDVSNLETLEKYRSFTRYFKLAEKESRKPRWWKTYRQYTNPEPGKPKTDISLPRDKVLRVRELKERKRILKQNHQNTEMERAARLRTALIPLDEVRAEWEKTSGPFHKQRLAEHYGIFRDLFQGATFTPWVSLRVGYNQEDEHLVPVYSGNIVTPSEASNPPEVSYEADKDSLWTLLLTNPDGHLRDTDSEYLHWLVTNIPGNDIKSGKEICHYLPPFPAMGTGYHRFIFLLFKQDRSIDFSEDVRPMPCYSLKMRTFSTFDFYRKHEDDMTPAGLAFFQCQWDSSVTWIFHQLLNMREPVFEFVRPPVYHPPQLKFPRQQPLRYLDRYRDTEEPTYGIY", "length": 380, "header": "tr|A0A8V1ANQ8-1|A0A8V1ANQ8_CHICK Isoform 1 of Large ribosomal subunit protein mL38 OS=Gallus gallus OX=9031 GN=MRPL38 PE=1 SV=1 CANONICAL=A0A8V1ANQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8/entry#A0A8V1AKM3-1", "sequence": { "sequence": "MPNEDIDVSNLETLEKYRSFTRYFKLAEKESRKPRWWKTYRQYTNPEPEHRLFQKGHGIRLVWVRRDLTATPELSLPWASWPRAHPGMGHPQLWAVPQPHCPLEPKTDISLPRDKVLRVRELKERKRILKQNHQNTEMERAARLRTALIPLDEVRAEWEKTSGPFHKQRLAEHYGIFRDLFQGATFTPWVSLRVGYNQEDEHLVPVYSGNIVTPSEASNPPEVSYEADKDSLWTLLLTNPDGHLRDTDSEYLHWLVTNIPGNDIKSGKEICHYLPPFPAMGTGYHRFIFLLFKQDRSIDFSEDVRPMPCYSLKMRTFSTFDFYRKHEDDMTPAGLAFFQCQWDSSVTWIFHQLLNMREPVFEFVRPPVYHPPQLKFPRQQPLRYLDRYRDTEEPTYGIY", "length": 399, "header": "tr|A0A8V1AKM3-1|A0A8V1ANQ8_CHICK Computationally mapped isoform of Large ribosomal subunit protein mL38 OS=Gallus gallus OX=9031 GN=MRPL38 PE=1 SV=1 CANONICAL=A0A8V1ANQ8-1" }, "locus": { "chromosome": "18", "start_pos": 5249733, "end_pos": 5245774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071996.1", "url": "https://www.ensembl.org/id/ENSGALT00010071996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044686.1", "url": "https://www.ensembl.org/id/ENSGALP00010044686.1" } ] } }, { "isoform_ac": "A0A8V1AM58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8/entry#A0A8V1AM58-1", "sequence": { "sequence": "MAAPLLSAALRGAWSGRAFGTAAALRKRAAPLGPMPNEDIDVSNLETLEKYRSFTRYFKLAEKESRKPRWWKTYRQYTNPEPEPKTDISLPRDKVLRVRELKERKRILKQNHQNTEMERAARLRTALIPLDEVRAEWEKTSGPFHKQRLAEHYGIFRDLFQGATFTPWVSLRVGYNQEDEHLVPVYSGNIVTPSEASNPPEVSYEADKDSLWTLLLTNPGEFLETCLTMLTNIPGNDIKSGKEICHYLPPFPAMGTGYHRFIFLLFKQDRSIDFSEDVRPMPCYSLKMRTFSTFDFYRKHEDDMTPAGLAFFQCQWDSSVTWIFHQLLNMREPVFEFVRPPVYHPPQLKFPRQQPLRYLDRYRDTEEPTYGIY", "length": 373, "header": "tr|A0A8V1AM58-1|A0A8V1AM58_CHICK Computationally mapped isoform of Large ribosomal subunit protein mL38 OS=Gallus gallus OX=9031 GN=MRPL38 PE=1 SV=1 CANONICAL=A0A8V1ANQ8-1" }, "locus": { "chromosome": "18", "start_pos": 5249733, "end_pos": 5245476, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071998.1", "url": "https://www.ensembl.org/id/ENSGALT00010071998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044688.1", "url": "https://www.ensembl.org/id/ENSGALP00010044688.1" } ] } }, { "isoform_ac": "A0A8V1ANQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8/entry#A0A8V1ANQ8-1", "sequence": { "sequence": "MMAAPLLSAALRGAWSGRAFGTAAALRKRAAPLGPMPNEDIDVSNLETLEKYRSFTRYFKLAEKESRKPRWWKTYRQYTNPEPGKPKTDISLPRDKVLRVRELKERKRILKQNHQNTEMERAARLRTALIPLDEVRAEWEKTSGPFHKQRLAEHYGIFRDLFQGATFTPWVSLRVGYNQEDEHLVPVYSGNIVTPSEASNPPEVSYEADKDSLWTLLLTNPDGHLRDTDSEYLHWLVTNIPGNDIKSGKEICHYLPPFPAMGTGYHRFIFLLFKQDRSIDFSEDVRPMPCYSLKMRTFSTFDFYRKHEDDMTPAGLAFFQCQWDSSVTWIFHQLLNMREPVFEFVRPPVYHPPQLKFPRQQPLRYLDRYRDTEEPTYGIY", "length": 380, "header": "tr|A0A8V1ANQ8-1|A0A8V1ANQ8_CHICK Isoform 1 of Large ribosomal subunit protein mL38 OS=Gallus gallus OX=9031 GN=MRPL38 PE=1 SV=1 CANONICAL=A0A8V1ANQ8-1" }, "locus": { "chromosome": "18", "start_pos": 5249733, "end_pos": 5245473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071997.1", "url": "https://www.ensembl.org/id/ENSGALT00010071997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044687.1", "url": "https://www.ensembl.org/id/ENSGALP00010044687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMG6-1", "uniprot_ac": "A0A8V1AMG6", "uniprot_id": "A0A8V1AMG6_CHICK", "mass": { "chemical_mass": 28376.0, "monoisotopic_mass": 28376.0 }, "refseq": {}, "gene_names": [ { "name": "SRSF1", "type": "recommended", "evidence": [ { "id": "A0A8V1AMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ] } ], "protein_names": [ { "name": "Splicing factor, arginine/serine-rich 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRSF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6", "locus": { "chromosome": "19", "start_pos": 9195355, "end_pos": 9191429, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029187", "url": "https://www.ensembl.org/id/ENSGALG00010029187" } ] } } ], "crossref": [ { "id": "A0A8V1AMG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005525", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005525", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12597", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12597", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "772264", "url": "https://www.ncbi.nlm.nih.gov/gene/772264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772264", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PREPAYP", "url": "https://omabrowser.org/oma/group/PREPAYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKR4", "url": "https://www.orthodb.org/?gene=A0A8V1AKR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMG6", "url": "https://www.orthodb.org/?gene=A0A8V1AMG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQW8", "url": "https://www.orthodb.org/?gene=F1NQW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AKR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQW8", "url": "https://www.uniprot.org/uniprotkb/F1NQW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQW8-1", "url": "https://www.uniprot.org/uniprotkb/F1NQW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSEYRVIVSGLPPSGSWQDLKDHMREAGDVCYADVFRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSHISEEMD", "length": 253, "header": "tr|A0A8V1AMG6-1|A0A8V1AMG6_CHICK Isoform 1 of Splicing factor, arginine/serine-rich 1 OS=Gallus gallus OX=9031 GN=SRSF1 PE=3 SV=1 CANONICAL=A0A8V1AMG6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6/entry#A0A8V1AKR4-1", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSEYRVIVSGLPPSGSWQDLKDHMREAGDVCYADVFRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEVGFTLTWFWPELDTKGLTVGREGKERVVFVELTHKAAKLSLLSVRHEIDFIKSLMSISAL", "length": 244, "header": "tr|A0A8V1AKR4-1|A0A8V1AMG6_CHICK Computationally mapped isoform of Splicing factor, arginine/serine-rich 1 OS=Gallus gallus OX=9031 GN=SRSF1 PE=3 SV=1 CANONICAL=A0A8V1AMG6-1" }, "locus": { "chromosome": "19", "start_pos": 9193157, "end_pos": 9191884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070542.1", "url": "https://www.ensembl.org/id/ENSGALT00010070542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043233.1", "url": "https://www.ensembl.org/id/ENSGALP00010043233.1" } ] } }, { "isoform_ac": "A0A8V1AMG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6/entry#A0A8V1AMG6-1", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSEYRVIVSGLPPSGSWQDLKDHMREAGDVCYADVFRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSHISEEMD", "length": 253, "header": "tr|A0A8V1AMG6-1|A0A8V1AMG6_CHICK Isoform 1 of Splicing factor, arginine/serine-rich 1 OS=Gallus gallus OX=9031 GN=SRSF1 PE=3 SV=1 CANONICAL=A0A8V1AMG6-1" }, "locus": { "chromosome": "19", "start_pos": 9193863, "end_pos": 9191884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070540.1", "url": "https://www.ensembl.org/id/ENSGALT00010070540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043231.1", "url": "https://www.ensembl.org/id/ENSGALP00010043231.1" } ] } }, { "isoform_ac": "F1NQW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6/entry#F1NQW8-1", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSEYRVIVSGLPPSGSWQDLKDHMREAGDVCYADVFRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT", "length": 248, "header": "tr|F1NQW8-1|F1NQW8_CHICK Computationally mapped isoform of Splicing factor, arginine/serine-rich 1 OS=Gallus gallus OX=9031 GN=SRSF1 PE=3 SV=2 CANONICAL=A0A8V1AMG6-1" }, "locus": { "chromosome": "19", "start_pos": 9193439, "end_pos": 9191884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070539.1", "url": "https://www.ensembl.org/id/ENSGALT00010070539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043230.1", "url": "https://www.ensembl.org/id/ENSGALP00010043230.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772264", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A9L2-1", "protein_name": "Serine/arginine-rich splicing factor 1", "gene_name": "Srsf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT", "length": 248 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4JHI7-1", "protein_name": "Serine/arginine-rich splicing factor SR34B", "gene_name": "SR34B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSRSSRTIYVGNLPGDIREREVEDLFSKYGPVVQIDLKIPPRPPGYAFVEFEDARDADDAIYGRDGYDFDGHHLRVELAHGGRRSSHDARGSYSGRGRGGRGGGDGGGRERGPSRRSEYRVVVSGLPSSASWQDLKDHMRKGGEVCFSQVFRDGRGTTGIVDYTSYEDMKYALDDTEFRNAFSHEYVRVREYDSRRDSRSPSRGRSYSKSRSRGRSPSRSRSRSRSRSKSRSPKAKSLRRSPAKSTSRSPRSRSRSKSRSLSPRGWVTVERHWIALI", "length": 278 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q01560-1", "protein_name": "Serine/arginine (SR)-type shuttling mRNA binding protein NPL3", "gene_name": "NPL3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEAQETHVEQLPESVVDAPVEEQHQEPPQAPDAPQEPQVPQESAPQESAPQEPPAPQEQNDVPPPSNAPIYEGEESHSVQDYQEAHQHHQPPEPQPYYPPPPPGEHMHGRPPMHHRQEGELSNTRLFVRPFPLDVQESELNEIFGPFGPMKEVKILNGFAFVEFEEAESAAKAIEEVHGKSFANQPLEVVYSKLPAKRYRITMKNLPEGCSWQDLKDLARENSLETTFSSVNTRDFDGTGALEFPSEEILVEALERLNNIEFRGSVITVERDDNPPPIRRSNRGGFRGRGGFRGGFRGGFRGGFSRGGFGGPRGGFGGPRGGYGGYSRGGYGGYSRGGYGGSRGGYDSPRGGYDSPRGGYSRGGYGGPRNDYGPPRGSYGGSRGGYDGPRGDYGPPRDAYRTRDAPRERSPTR", "length": 414 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07955-1", "protein_name": "Serine/arginine-rich splicing factor 1", "gene_name": "SRSF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT", "length": 248 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0VCY7-1", "protein_name": "Serine/arginine-rich splicing factor 1", "gene_name": "SRSF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT", "length": 248 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3YLA6-1", "protein_name": "Serine/arginine-rich splicing factor 1", "gene_name": "SRSF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT", "length": 248 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NYA0-1", "protein_name": "Serine/arginine-rich splicing factor 1B", "gene_name": "srsf1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGGVIRGPAGNNDCRIYVGNLPPDIRTKDVEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGGGRGGGGGGGVGAPRGRYGPPSRRSEYRVIVSGLPPSGSWQDLKDHMREAGDVCYADVFRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT", "length": 245 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PDM2-1", "protein_name": "Serine/arginine-rich splicing factor 1", "gene_name": "Srsf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT", "length": 248 }, "evidence": [ { "id": "A0A8V1AMG6", "url": "https://omabrowser.org/oma/group/A0A8V1AMG6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "DNA topoisomerase binding", "id": "GO:0044547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044547", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "RS domain binding", "id": "GO:0050733", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050733", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "protein localization to P-body", "id": "GO:0110012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "interleukin-17-mediated signaling pathway", "id": "GO:0097400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 91, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AQ62-1", "uniprot_ac": "A0A8V1AQ62", "uniprot_id": "A0A8V1AQ62_CHICK", "mass": { "chemical_mass": 125915.0, "monoisotopic_mass": 125915.0 }, "refseq": { "ac": "XP_415627", "name": "protein unc-13 homolog D isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415627" }, "gene_names": [ { "name": "UNC13D", "type": "recommended", "evidence": [ { "id": "A0A8V1AQ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62" } ] }, { "name": "UNC13D", "type": "synonym", "evidence": [ { "id": "XP_415627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415627" } ] } ], "protein_names": [ { "name": "Unc-13 homolog D", "type": "synonym", "evidence": [ { "id": "A0A8V1AQ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62/entry#names_and_taxonomy" } ] }, { "name": "protein unc-13 homolog D isoform X4", "type": "synonym", "evidence": [ { "id": "XP_415627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415627" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415627.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415627" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNC13D", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62", "locus": { "chromosome": "18", "start_pos": 5287103, "end_pos": 5273589, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029781", "url": "https://www.ensembl.org/id/ENSGALG00010029781" } ] } } ], "crossref": [ { "id": "A0A8V1AQ62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AQ62", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417369", "url": "https://www.ncbi.nlm.nih.gov/gene/417369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFD5", "url": "https://www.orthodb.org/?gene=A0A8V1AFD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKS7", "url": "https://www.orthodb.org/?gene=A0A8V1AKS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMA0", "url": "https://www.orthodb.org/?gene=A0A8V1AMA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANU4", "url": "https://www.orthodb.org/?gene=A0A8V1ANU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ62", "url": "https://www.orthodb.org/?gene=A0A8V1AQ62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45999:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45999:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415627", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ62", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGRAPMGTLPREEESPEMDLSHRFSKQELALLYQEVLYTIQHRLGKPQPQHVADAQELCAYVQKAFGMDAEEHRAIMQQVQELESPIFCLKATVKEAKGILGKDVSGFSDPYCLLGIESKNQEPAHPDSKRRLKAVVKDLIPEDQIHRTQIISQTLNPVWDETFILEFEDMETASFHLDMWDSDTVESVRHKLGELTDLHGLKRIFKDARKDKGQDDFLGNVVLRLKDLHCWDDQWYQLEPRTETYPNRGQCHLQFLLTHKKRATTCSRTQPSYTVHRHLLQQLVSHEILQHQAGSTAWDGELSPHASTVLYLHATQKDLSDFHQVMAQWLAYSKLYQSLEFNSSCLLHQITSIEYQWVQERLRPEQKAELAESFQSLLTYGVSLIRRYRIIFPLSVARSTERLQSLLRVLVQMCKMKAFRELCTPSPDLPRMVSEALKSGTAEWFHMKKQHLQPMVKSMEENGKALAKLLLEVIGDLQQCQKIWNKFFISTLKLNLFSIAYLELESLVAEHVQEQLREIDTGMSKPTAESLFQLYLNLQELYRMKDFLPKRDGPLALSDFHQWFKEAVPQWLQKAYSIALERAQRAVQMDQLTPFGEHNKHSTSTVDLSTCYAQIVKTWQQLNWPDPEEAFMIMVKLVEDMCKIALMYCRLVKERAEALSLCEQNEGEAANRLCIVVNNIKQLRLLVLKLPWQLDWAQLEQRTGAVIDQQQIQHTLHHQLDSTVSCLDREVQDVVQALATKLEAGIARHIQELSASNNAQEPEDSILPLMKFLESELQYLNEHLVQENFKSLLALLWHHTLAVLTAAAGPQVPSVQHCRKLHCALKSLELCFHAEGCGLPLETLHSTAFLSLESRLALCSSTSRKLIQKYFSNRIQEQLDISSEKYGAVTIKALYRPSEQKLRVEVLNAANLIPLDSNASSPPRSAARTGPVCCSPSSITTPWGPTTWRERPSSPCATCLAWMPMRTDPTRDGCPKRASRSPTPNPAAMRSCGCWSAGRGTRRPRPSSSCASSEPSSPRRRREGQRALNGGVQSGIPWGQQALPPAVPPVGLRRVVGWLGVSLQTNTTLPGRVPSPSALHGAAASVWGWGNLPPWLSGLFGFFSLLF", "length": 1111, "header": "tr|A0A8V1AQ62-1|A0A8V1AQ62_CHICK Isoform 1 of Unc-13 homolog D OS=Gallus gallus OX=9031 GN=UNC13D PE=3 SV=1 CANONICAL=A0A8V1AQ62-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62/entry#A0A8V1AFD5-1", "sequence": { "sequence": "MAAAGRAPMGTLPREEESPEMDLSHRFSKQELALLYQEVLYTIQHRLGKPQPQHVADAQELCAYVQKAFGMDAEEHRAIMQQVQELESPIFCLKATVKEAKGILGKDVSGFSDPYCLLGIESKNQEPAHPDSKRRLKAVVKDLIPEDQIHRTQIISQTLNPVWDETFILEFEDMETASFHLDMWDSDTVESVRHKLGELTDLHGLKRIFKDARKDKGQDDFLGNVVLRLKDLHCWDDQWYQLEPRTETYPNRGQCHLQFLLTHKKRATTCSRTQPSYTVHRHLLQQLVSHEILQHQAGSTAWDGELSPHASTVLYLHATQKDLSDFHQVMAQWLAYSKLYQSLEFNSSCLLHQITSIEYQWVQERLRPEQKAELAESFQSLLTYGVSLIRRYRIIFPLSVARSTERLQSLLRVLVQMCKMKAFRELCTPSPDLPRMVSEALKSGTAEWFHMKKQHLQPMVKSMEENGKALAKLLLEVIGDLQQCQKIWNKFFISTLKLNLFSIAYLELESLVAEHVQEQLREIDTGMSKPTAESLFQLYLNLQELYRMKDFLPKRDGPLALSDFHQWFKEAVPQWLQKAYSIALERAQRAVQMDQLTPFGEHNKHSTSTVDLSTCYAQIVKTWQQLNWPDPEEAFMIMVKLVEDMCKIALMYCRLVKERAEALSLCEQNEGEAANRLCIVVNNIKQLRLLVLKLPWQLDWAQLEQRTGAVIDQQQIQHTLHHQLDSTVSCLDREVQDVVQALATKLEAGIARHIQELSASNNAQEPEDSILPLMKFLESELQYLNEHLVQENFKSLLALLWHHTLAVLTAAAGPQVPSVQHCRKLHCALKSLELCFHAEGCGLPLETLHSTAFLSLESRLALCSSTSRKLIQKYFSNRIQEQLDISSEKYGAVTIKALYRPSEQKLRVEVLNAANLIPLDSNGSSDPFVQLTLEPRHEFPEVVARSTQCKRNELHPLFDEAFEFLIPPEKCRQDGACLLLTVFDYDTLGANDLEGEAFFPLRHLPGLDADEDRPDTGWVPQTRLPLTHPKPGGDEILRLLECRKGDKEAQAFVKLRKQRAKQSKETA", "length": 1067, "header": "tr|A0A8V1AFD5-1|A0A8V1AFD5_CHICK Computationally mapped isoform of Unc-13 homolog D OS=Gallus gallus OX=9031 GN=UNC13D PE=3 SV=1 CANONICAL=A0A8V1AQ62-1" }, "locus": { "chromosome": "18", "start_pos": 5286825, "end_pos": 5276873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072045.1", "url": "https://www.ensembl.org/id/ENSGALT00010072045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044735.1", "url": "https://www.ensembl.org/id/ENSGALP00010044735.1" } ] } }, { "isoform_ac": "A0A8V1AKS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62/entry#A0A8V1AKS7-1", "sequence": { "sequence": "MCVMTASVLSPNSFGVSVCRGMDLSHRFSKQELALLYQEVLYTIQHRLGKPQPQHVADAQELCAYVQKAFGMDAEEHRAIMQQVQELESPIFCLKATVKEAKGILGKDVSGFSDPYCLLGIESKNQEPAHPDSKRRLKAVVKDLIPEDQIHRTQIISQTLNPVWDETFILEFEDMETASFHLDMWDSDTVESVRHKLGELTDLHGLKRIFKDARKDKGQDDFLGNVVLRLKDLHCWDDQWYQLEPRTETYPNRGQCHLQFLLTHKKRATTCSRTQPSYTVHRHLLQQLVSHEILQHQAGSTAWDGELSPHASTVLYLHATQKDLSDFHQVMAQWLAYSKLYQSLEFNSSCLLHQITSIEYQWVQERLRPEQKAELAESFQSLLTYGVSLIRRYRIIFPLSVARSTERLQSLLRVLVQMCKMKAFRELCTPSPDLPRMVSEALKSGTAEWFHMKKQHLQPMVKSMEENGKALAKLLLEVIGDLQQCQKIWNKFFISTLKLNLFSIAYLELESLVAEHVQEQLREIDTGMSKPTAESLFQLYLNLQELYRMKDFLPKRDGPLALSDFHQWFKEAVPQWLQKAYSIALERAQRAVQMDQLTPFGEHNKHSTSTVDLSTCYAQIVKTWQQLNWPDPEEAFMIMVKLVEDMCKIALMYCRLVKERAEALSLCEQNEGEAANRLCIVVNNIKQLRLLVLKLPWQLDWAQLEQRTGAVIDQQQIQHTLHHQLDSTVSCLDREVQDVVQALATKLEAGIARHIQELSASNNAQEPEDSILPLMKFLESELQYLNEHLVQENFKSLLALLWHHTLAVLTAAAGPQVPSVQHCRKLHCALKSLELCFHAEGCGLPLETLHSTAFLSLESRLALCSSTSRKLIQKYFSNRIQEQLDISSEKYGAVTIKALYRPSEQKLRVEVLNAANLIPLDSNGSSDPFVQLTLEPRHEFPEVVARSTQCKRNELHPLFDEAFEFLIPPEKCRQDGACLLLTVFDYDTLGANDLEGEAFFPLRHLPGLDADEDRPDTGWVPQTRLPLTHPKPGGDEILRLLECRKGDKEAQAFVKLRKQRAKQSKETA", "length": 1068, "header": "tr|A0A8V1AKS7-1|A0A8V1AQ62_CHICK Computationally mapped isoform of Unc-13 homolog D OS=Gallus gallus OX=9031 GN=UNC13D PE=3 SV=1 CANONICAL=A0A8V1AQ62-1" }, "locus": { "chromosome": "18", "start_pos": 5286825, "end_pos": 5276372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072047.1", "url": "https://www.ensembl.org/id/ENSGALT00010072047.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044737.1", "url": "https://www.ensembl.org/id/ENSGALP00010044737.1" } ] } }, { "isoform_ac": "A0A8V1AMA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62/entry#A0A8V1AMA0-1", "sequence": { "sequence": "MDLSHRFSKQELALLYQEVLYTIQHRLGKPQPQHVADAQELCAYVQKAFGMDAEEHRAIMQQVQELESPIFCLKATVKEAKGILGKDVSGFSDPYCLLGIESKNQEPAHPDSKRRLKAVVKDLIPEDQIHRTQIISQTLNPVWDETFILEFEDMETASFHLDMWDSDTVESVRHKLGELTDLHGLKRIFKDARKDKGQDDFLGNVVLRLKDLHCWDDQWYQLEPRTETYPNRGQCHLQFLLTHKKRATTCSRTQPSYTVHRHLLQQLVSHEILQHQAGSTAWDGELSPHASTVLYLHATQKDLSDFHQVMAQWLAYSKLYQSLEFNSSCLLHQITSIEYQWVQERLRPEQVGHGEKAELAESFQSLLTYGVSLIRRYRIIFPLSVARSTERLQSLLRVLVQMCKMKAFRELCTPSPDLPRMVSEALKSGTAEWFHMKKQHLQPMVKSMEENGKALAKLLLEVIGDLQQCQKIWNKFFISTLKLNLFSIAYLELESLVAEHVQEQLREIDTGMSKPTAESLFQLYLNLQELYRMKDFLPKRDGPLALSDFHQWFKEAVPQWLQKAYSIALERAQRAVQMDQLTPFGEHNKHSTSTVDLSTCYAQIVKTWQQLNWPDPEEAFMIMVKLVEDMCKIALMYCRLVKERAEALSLCEQNEGEAANRLCIVVNNIKQLRLLVLKLPWQLDWAQLEQRTGAVIDQQQIQHTLHHQLDSTVSCLDREVQDVVQALATKLEAGIARHIQELSASNNAQEPEDSILPLMKFLESELQYLNEHLVQENFKSLLALLWHHTLAVLTAAAGPQVPSVQHCRKLHCALKSLELCFHAEGCGLPLETLHSTAFLSLESRLALCSSTSRKLIQKYFSNRIQEQLDISSEKYGAVTIKALYRPSEQKLRVEVLNAANLIPLDSNGSSDPFVQLTLEPRHEFPEVVARSTQCKRNELHPLFDEAFEFLIPPEKCRQDGACLLLTVFDYDTLGANDLEGEAFFPLRHLPGLDADEDRPDTGWVPQTRLPLTHPKPGGDEILRLLECRKGDKEAQAFVKLRKQRAKQSKETA", "length": 1052, "header": "tr|A0A8V1AMA0-1|A0A8V1AMA0_CHICK Computationally mapped isoform of Unc-13 homolog D OS=Gallus gallus OX=9031 GN=UNC13D PE=3 SV=1 CANONICAL=A0A8V1AQ62-1" }, "locus": { "chromosome": "18", "start_pos": 5286825, "end_pos": 5277715, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072044.1", "url": "https://www.ensembl.org/id/ENSGALT00010072044.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044734.1", "url": "https://www.ensembl.org/id/ENSGALP00010044734.1" } ] } }, { "isoform_ac": "A0A8V1ANU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62/entry#A0A8V1ANU4-1", "sequence": { "sequence": "MSVSKHGLCEAPKSLAQHHVQYSSRASSQHKHMDLSHRFSKQELALLYQEVLYTIQHRLGKPQPQHVADAQELCAYVQKAFGMDAEEHRAIMQQVQELESPIFCLKATVKEAKGILGKDVSGFSDPYCLLGIESKNQEPAHPDSKRRLKAVVKDLIPEDQIHRTQIISQTLNPVWDETFILEFEDMETASFHLDMWDSDTVESVRHKLGELTDLHGLKRIFKDARKDKGQDDFLGNVVLRLKDLHCWDDQWYQLEPRTETYPNRGQCHLQFLLTHKKRATTCSRTQPSYTVHRHLLQQLVSHEILQHQAGSTAWDGELSPHASTVLYLHATQKDLSDFHQVMAQWLAYSKLYQSLEFNSSCLLHQITSIEYQWVQERLRPEQKAELAESFQSLLTYGVSLIRRYRIIFPLSVARSTERLQSLLRVLVQMCKMKAFRELCTPSPDLPRMVSEALKSGTAEWFHMKKQHLQPMVKSMEENGKALAKLLLEVIGDLQQCQKIWNKFFISTLKLNLFSIAYLELESLVAEHVQEQLREIDTGMSKPTAESLFQLYLNLQELYRMKDFLPKRDGPLALSDFHQWFKEAVPQWLQKAYSIALERAQRAVQMDQLTPFGEHNKHSTSTVDLSTCYAQIVKTWQQLNWPDPEEAFMIMVKLVEDMCKIALMYCRLVKERAEALSLCEQNEGEAANRLCIVVNNIKQLRLLVLKLPWQLDWAQLEQRTGAVIDQQQIQHTLHHQLDSTVSCLDREVQDVVQALATKLEAGIARHIQELSASNNAQEPEDSILPLMKFLESELQYLNEHLVQENFKSLLALLWHHTLAVLTAAAGPQVPSVQHCRKLHCALKSLELCFHAEGCGLPLETLHSTAFLSLESRLALCSSTSRKLIQKYFSNRIQEQLDISSEKYGAVTIKALYRPSEQKLRVEVLNAANLIPLDSNGSSDPFVQLTLEPRHEFPEVVARSTQCKRNELHPLFDEAFEFLIPPEKCRQDGACLLLTVFDYDTLGANDLEGEAFFPLRHLPGLDADEDRPDTGWVPQTRLPLTHPKPGGDEILRLLECRKGDKEAQAFVKLRKQRAKQSKETA", "length": 1079, "header": "tr|A0A8V1ANU4-1|A0A8V1ANU4_CHICK Computationally mapped isoform of Unc-13 homolog D OS=Gallus gallus OX=9031 GN=UNC13D PE=3 SV=1 CANONICAL=A0A8V1AQ62-1" }, "locus": { "chromosome": "18", "start_pos": 5286825, "end_pos": 5273594, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072048.1", "url": "https://www.ensembl.org/id/ENSGALT00010072048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044738.1", "url": "https://www.ensembl.org/id/ENSGALP00010044738.1" } ] } }, { "isoform_ac": "A0A8V1AQ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ62/entry#A0A8V1AQ62-1", "sequence": { "sequence": "MAAAGRAPMGTLPREEESPEMDLSHRFSKQELALLYQEVLYTIQHRLGKPQPQHVADAQELCAYVQKAFGMDAEEHRAIMQQVQELESPIFCLKATVKEAKGILGKDVSGFSDPYCLLGIESKNQEPAHPDSKRRLKAVVKDLIPEDQIHRTQIISQTLNPVWDETFILEFEDMETASFHLDMWDSDTVESVRHKLGELTDLHGLKRIFKDARKDKGQDDFLGNVVLRLKDLHCWDDQWYQLEPRTETYPNRGQCHLQFLLTHKKRATTCSRTQPSYTVHRHLLQQLVSHEILQHQAGSTAWDGELSPHASTVLYLHATQKDLSDFHQVMAQWLAYSKLYQSLEFNSSCLLHQITSIEYQWVQERLRPEQKAELAESFQSLLTYGVSLIRRYRIIFPLSVARSTERLQSLLRVLVQMCKMKAFRELCTPSPDLPRMVSEALKSGTAEWFHMKKQHLQPMVKSMEENGKALAKLLLEVIGDLQQCQKIWNKFFISTLKLNLFSIAYLELESLVAEHVQEQLREIDTGMSKPTAESLFQLYLNLQELYRMKDFLPKRDGPLALSDFHQWFKEAVPQWLQKAYSIALERAQRAVQMDQLTPFGEHNKHSTSTVDLSTCYAQIVKTWQQLNWPDPEEAFMIMVKLVEDMCKIALMYCRLVKERAEALSLCEQNEGEAANRLCIVVNNIKQLRLLVLKLPWQLDWAQLEQRTGAVIDQQQIQHTLHHQLDSTVSCLDREVQDVVQALATKLEAGIARHIQELSASNNAQEPEDSILPLMKFLESELQYLNEHLVQENFKSLLALLWHHTLAVLTAAAGPQVPSVQHCRKLHCALKSLELCFHAEGCGLPLETLHSTAFLSLESRLALCSSTSRKLIQKYFSNRIQEQLDISSEKYGAVTIKALYRPSEQKLRVEVLNAANLIPLDSNASSPPRSAARTGPVCCSPSSITTPWGPTTWRERPSSPCATCLAWMPMRTDPTRDGCPKRASRSPTPNPAAMRSCGCWSAGRGTRRPRPSSSCASSEPSSPRRRREGQRALNGGVQSGIPWGQQALPPAVPPVGLRRVVGWLGVSLQTNTTLPGRVPSPSALHGAAASVWGWGNLPPWLSGLFGFFSLLF", "length": 1111, "header": "tr|A0A8V1AQ62-1|A0A8V1AQ62_CHICK Isoform 1 of Unc-13 homolog D OS=Gallus gallus OX=9031 GN=UNC13D PE=3 SV=1 CANONICAL=A0A8V1AQ62-1" }, "locus": { "chromosome": "18", "start_pos": 5287081, "end_pos": 5276873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072046.1", "url": "https://www.ensembl.org/id/ENSGALT00010072046.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044736.1", "url": "https://www.ensembl.org/id/ENSGALP00010044736.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 950, "start_aa": "Thr", "end_pos": 950, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr950", "evidence": [ { "id": "GLY_001161", "database": 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domain containing 57 OS=Gallus gallus OX=9031 GN=CCDC57 PE=4 SV=1 CANONICAL=A0A8V1ANX0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0/entry#A0A8V1AFH8-1", "sequence": { "sequence": "MSTEGTRSKNDHTNHQHEQCVSLRRHVERKLQGLQGELPGQKQVKLLTRELEALRETGMKASESPQAAELVNLQLEKEDKYKNWELNDAVAVRNAWEEGPSHVDKEKDTVSASLEEAPIKQFKKLKKQIRELQMRQKSLEAKLRRKAGNHSARVREKDALIKKYKQQLSVAAEQEQLLEQSKTHAELDWQPCGNAENHEYQKLEDLTPSVSLAREQAEADLQKTDYSLHEVESVPSTFSDKRQQLLQSPLSNRGVLPEGEKQAFQSDDKSYLRKDIPGSEIQKLQEQNANLRAVIAQMRKEMESLDEQTPSSVPQREQSAPGHTAGISALTAAVLMGRAEGALCTDQVSGRTTSSNMDVSSASSGCIVNPGTGKGSNNRVMDKEIQHGVSCTPQGTPNKLRDAVRTTSVLSQEKQQLIEMGNRLRTDLGMILKEGFWHPISPKLCTVCVGSGGLSPRELVKRTQCQLSALRHLQQQLITQELQYAKQQHLSRISSLIACPILKGEKAPSSCGEETEPLSAEVQLSSSAANYGPKQQKAAAASSRVQSQPPKESSGQAQQVWISSSGAHSPCQGNWQTLEMGSSSSPLCPQNNAKQVEFEILHSTEQPGEHQEHSNATGRPEMPTAHLAVRALLSQYCSQTAVPSHTCSTAVTDLRATRTITFLSFLLNTLCFRTHVLRHHNRNPNPAVHVTEVL", "length": 694, "header": "tr|A0A8V1AFH8-1|A0A8V1AFH8_CHICK Computationally mapped isoform of Coiled-coil domain containing 57 OS=Gallus gallus OX=9031 GN=CCDC57 PE=4 SV=1 CANONICAL=A0A8V1ANX0-1" }, "locus": { "chromosome": "18", "start_pos": 5534928, "end_pos": 5505907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072251.1", "url": "https://www.ensembl.org/id/ENSGALT00010072251.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044777.1", "url": "https://www.ensembl.org/id/ENSGALP00010044777.1" } ] } }, { "isoform_ac": "A0A8V1AKW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0/entry#A0A8V1AKW5-1", "sequence": { "sequence": "MCVLLPCGGNQPRQRRSAAAGEVDQVTLRVPSNPSRCMTVWSFLSHPLFGGFGRNAGNAASALLECYTHITPGAQKGEASVHSLCFEHSDEDWGLLDRFIPVLLKEWEELLQWKEKERKEQQNWQFPAQKEMLHVVVKQLHDMHENYNKLKEDFIYNLRILEERDKELESYDVTFSHLKTSEKAKQAEISNLKIQLDKLEQLLVKERRKRAELHYRYQQNLEEHQLELEQFCRSKNDHTNHQHEQCVSLRRHVERKLQGLQGELPGQKQVKLLTRELEALRETGMKASESPQAAELVNLQLEKEDKYKNWELNDAVAVRNAWEEGPSHVDKEKDTVSASLEEAPIKQFKKLKKQIRELQMRQKSLEAKLRRKAGNHSARVREKDALIKKYKQQLSVAAEQEQLLEQSKTHAELDWQPCGNAENHEYQKLEDLTPSVSLAREQAEADLQKTDYSLHEVESVPSTFSDKRQQLLQSPLSNRGVLPEGEKQAFQSDDKSYLRKDIPGSEIQKLQEQNANLRAVIAQMRKEMESLDEQTPSSVPQREQSAPGHTAGISALTAAVLMGRAEGALCTDQVSGRTTSSNMDVSSASSGCIVNPGTGKGSNNRVMDKEIQHGVSCTPQGTPNKLRDAVRTTSVLSQEKQQLIEMGNRLRTDLGMILKEGFWHPISPKLCTVCVGSGGLSPRELVKRTQCQLSALRHLQQQLITQELQYAKQQHLSRISSLIACPILKGEKAPSSCGEETEPLSAEVQLSSSAANYGPKQQKAAAASSRVQSQPPKESSGQAQQVWISSSGAHSPCQGNWQTLEMGSSSSPLCPQNNAKQVEFEILHSTEQPGEHQEHSNATGRPEMPTAHLAVRGTKLEVQQKLKSRNSPCIQPIKRKISPTVAKIRNYNIKD", "length": 895, "header": "tr|A0A8V1AKW5-1|A0A8V1ANX0_CHICK Computationally mapped isoform of Coiled-coil domain containing 57 OS=Gallus gallus OX=9031 GN=CCDC57 PE=4 SV=1 CANONICAL=A0A8V1ANX0-1" }, "locus": { "chromosome": "18", "start_pos": 5533535, "end_pos": 5506768, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072247.1", "url": "https://www.ensembl.org/id/ENSGALT00010072247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044774.1", "url": "https://www.ensembl.org/id/ENSGALP00010044774.1" } ] } }, { "isoform_ac": "A0A8V1AMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0/entry#A0A8V1AMD3-1", "sequence": { "sequence": "MSTEGTRFIPVLLKEWEELLQWKEKERKEQQNWQFPAQKEMLHVVVKQLHDMHENYNKLKEDFIYNLRILEERDKELESYDVTFSHLKTSEKAKQAEISNLKIQLDKLEQLLVKERRKRAELHYRYQQNLEEHQLELEQFCRSKNDHTNHQHEQCVSLRRHVERKLQGLQGELPGQKQVKLLTRELEALRETGMKASESPQAAELVNLQLEKEDKYKNWELNDAVAVRNAWYCTISTTIRLNWYKQQLSVAAEQEQLLEQSKTHAELDWQPCGNAENHEYQKLEDLTPSVSLAREQAEADLQKTDYSLHEVESVPSTFSDKRQQLLQSPLSNRGVLPEGEKQAFQSDDKSYLRKDIPGSEIQKLQEQNANLRAVIAQMRKEMESLDEQTPSSVPQREQSAPGHTAGISALTAAVLMGRAEGALCTDQVSGRTTSSNMDVSSASSGCIVNPGTGKGSNNRVMDKEIQHGVSCTPQGTPNKLRDAVRTTSVLSQEKQQLIEMGNRLRTDLGMILKEGFWHPISPKLCTVCVGSGGLSPRELVKRTQCQLSALRHLQQQLITQELQYAKQQHLSRISSLIACPILKGEKAPSSCGEETEPLSAEVQLSSSAANYGPKQQKAAAASSRVQSQPPKESSGQAQQVWISSSGAHSPCQGNWQTLEMGSSSSPLCPQNMEFEILHSTEQPGEHQEHSNATGRPEMPTAHLAVRALLSQYCSQTAVPSHTCSTAVTDLRATRTITFLSFLLNTLCFRTHVLRHHNRNPNPAVHVTEVL", "length": 770, "header": "tr|A0A8V1AMD3-1|A0A8V1AMD3_CHICK Computationally mapped isoform of Coiled-coil domain containing 57 OS=Gallus gallus OX=9031 GN=CCDC57 PE=4 SV=1 CANONICAL=A0A8V1ANX0-1" }, "locus": { "chromosome": "18", "start_pos": 5534928, "end_pos": 5505907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072249.1", "url": "https://www.ensembl.org/id/ENSGALT00010072249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044776.1", "url": "https://www.ensembl.org/id/ENSGALP00010044776.1" } ] } }, { "isoform_ac": "A0A8V1ANX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0/entry#A0A8V1ANX0-1", "sequence": { "sequence": "MFVLIFIYIYIYYLSNTFLRVLSEQEVHSFEGELAQKEGFSWLVFERSVPWLCSLRSPQCGSQSSPSCCPGEHLCVPRAEMRVKGMGSAVQVMLGWGPEQPSQRAGTTDGVLRRDVGLTRGAAWKKDCWMSTEGTRFIPVLLKEWEELLQWKEKERKEQQNWQFPAQKEMLHVVVKQLHDMHENYNKLKEDFIYNLRILEERDKELESYDVTFSHLKTSEKAKQAEISNLKIQLDKLEQLLVKERRKRAELHYRYQQNLEEHQLELEQFCRSKNDHTNHQHEQCVSLRRHVERKLQGLQGELPGQKQVKLLTRELEALRETGMKASESPQAAELVNLQLEKEDKYKNWELNDAVAVRNAWEEGPSHVDKEKDTVSASLEEAPIKQFKKLKKQIRELQMRQKSLEAKLRRKAGNHSARVREKDALIKKYKQQLSVAAEQEQLLEQSKTHAELDWQPCGNAENHEYQKLEDLTPSVSLAREQAEADLQKTDYSLHEVESVPSTFSDKRQQLLQSPLSNRGVLPEGEKQAFQSDDKSYLRKDIPGSEIQKLQEQNANLRAVIAQMRKEMESLDEQTPSSVPQREQSAPGHTAGISALTAAVLMGRAEGALCTDQVSGRTTSSNMDVSSASSGCIVNPGTGKGSNNRVMDKEIQHGVSCTPQGTPNKLRDAVRTTSVLSQEKQQLIEMGNRLRTDLGMILKEGFWHPISPKLCTVCVGSGGLSPRELVKRTQCQLSALRHLQQQLITQELQYAKQQHLSRISSLIACPILKGEKAPSSCGEETEPLSAEVQLSSSAANYGPKQQKAAAASSRVQSQPPKESSGQAQQVWISSSGAHSPCQVEFEILHSTEQPGEHQEHSNATGRPEMPTAHLAVRGTKLEVQQKLKSRNSPCIQPIKRKISPTVAKIRNYNIKD", "length": 910, "header": "tr|A0A8V1ANX0-1|A0A8V1ANX0_CHICK Isoform 1 of Coiled-coil domain containing 57 OS=Gallus gallus OX=9031 GN=CCDC57 PE=4 SV=1 CANONICAL=A0A8V1ANX0-1" }, "locus": { "chromosome": "18", "start_pos": 5533535, "end_pos": 5504754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072248.1", "url": "https://www.ensembl.org/id/ENSGALT00010072248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044775.1", "url": "https://www.ensembl.org/id/ENSGALP00010044775.1" } ] } }, { "isoform_ac": "A0A8V1AQ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0/entry#A0A8V1AQ81-1", "sequence": { "sequence": "MLHVVVKQLHDMHENYNKLKEDFIYNLRILEERDKELESYDVTFSHLKTSEKAKQAEISNLKIQLDKLEQLLVKERRKRAELHYRYQQNLEEHQLELEQFCRSKNDHTNHQHEQCVSLRRHVERKLQGLQGELPGQKQVKLLTRELEALRETGMKASESPQAAELVNLQLEKEDKYKNWELNDAVAVRNAWEEGPSHVDKEKDTVSASLEEAPIKQFKKLKKQIRELQMRQKSLEAKLRRKAGNHSARVREKDALIKKYKQQLSVAAEQEQLLEQSKTHAELDWQPCGNAENHEYQKLEDLTPSVSLAREQAEADLQKTDYSLHEVESVPSTFSDKRQQLLQSPLSNRGVLPEGEKQAFQSDDKSYLRKDIPGSEIQKLQEQNANLRAVIAQMRKEMESLDEQTPSSVPQREQSAPGHTAGISALTAAVLMGRAEGALCTDQVSGRTTSSNMDVSSASSGCIVNPGTGKGSNNRVMDKEIQHGVSCTPQGTPNKLRDAVRTTSVLSQEKQQLIEMGNRLRTDLGMILKEGFWHPISPKLCTVCVGSGGLSPRELVKRTQCQLSALRHLQQQLITQELQYAKQQHLSRISSLIACPILKGEKAPSSCGEETEPLSAEVQLSSSAANYGPKQQKAAAASSRVQSQPPKESSGQAQQVWISSSGAHSPCQGNWQTLEMGSSSSPLCPQNNAKQGEHALQIITVFNSSRRNQVQ", "length": 710, "header": "tr|A0A8V1AQ81-1|A0A8V1AQ81_CHICK Computationally mapped isoform of Coiled-coil domain containing 57 OS=Gallus gallus OX=9031 GN=CCDC57 PE=4 SV=1 CANONICAL=A0A8V1ANX0-1" }, "locus": { "chromosome": "18", "start_pos": 5526210, "end_pos": 5509883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072246.1", "url": "https://www.ensembl.org/id/ENSGALT00010072246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044773.1", "url": "https://www.ensembl.org/id/ENSGALP00010044773.1" } ] } }, { "isoform_ac": "A0A8V1AQ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0/entry#A0A8V1AQ85-1", "sequence": { "sequence": "MSTEGTRFIPVLLKEWEELLQWKEKERKEQQNWQFPAQKEMLHVVVKQLHDMHENYNKLKEDFIYNLRILEERDKELESYDVTFSHLKTSEKAKQAEISNLKIQLDKLEQLLVKERRKRAELHYRYQQNLEEHQLELEQFCRSKNDHTNHQHEQCVSLRRHVERKLQGLQGELPGQKQVKLLTRELEALRETGMKASESPQAAELVNLQLEKEDKYKNWELNDAVAVRNAWEEGPSHVDKEKDTVSASLEEAPIKQFKKLKKQIRELQMRQKSLEAKLRRKAGNHSARVREKDALIKKYKQQLSVAAEQEQLLEQSKTHAELDWQPCGNAENHEYQKLEDLTPSVSLAREQAEADLQKTDYSLHEVESVPSTFSDKRQQLLQSPLSNRGVLPEGEKQAFQSDDKSYLRKDIPGSEIQKLQEQNANLRAVIAQMRKEMESLDEQTPSSVPQREQSAPGHTAGISALTAAVLMGRAEGALCTDQVSGRTTSSNMDVSSASSGCIVNPGTGKGSNNRVMDKEIQHGVSCTPQGTPNKLRDAVRTTSVLSQEKQQLIEMGNRLRTDLGMILKEGFWHPISPKLCTVCVGSGGLSPRELVKRTQCQLSALRHLQQQLITQELQYAKQQHLSRISSLIACPILKGEKAPSSCGEETEPLSAEVQLSSSAANYGPKQQKAAAASSRVQSQPPKESSGQAQQVWISSSGAHSPCQGNWQTLEMGSSSSPLCPQNNAKQVEFEILHSTEQPGEHQEHSNATGRPEMPTAHLAVRALLSQYCSQTAVPSHTCSTAVTDLRATRTITFLSFLLNTLCFRTHVLRHHNRNPNPAVHVTEVL", "length": 829, "header": "tr|A0A8V1AQ85-1|A0A8V1AQ85_CHICK Computationally mapped isoform of Coiled-coil domain containing 57 OS=Gallus gallus OX=9031 GN=CCDC57 PE=4 SV=1 CANONICAL=A0A8V1ANX0-1" }, "locus": { "chromosome": "18", "start_pos": 5534928, "end_pos": 5505907, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072254.1", "url": "https://www.ensembl.org/id/ENSGALT00010072254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044778.1", "url": "https://www.ensembl.org/id/ENSGALP00010044778.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 899, "start_aa": "Thr", "end_pos": 899, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr899", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of mitotic cell cycle", "id": "GO:0045931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045931", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0" } ], "pmid": "" }, { "name": "microtubule nucleation", "id": "GO:0007020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0" } ], "pmid": "" }, { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 856, "end_pos": 858, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 899 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 413, "end_pos": 415 }, { "start_pos": 856, "end_pos": 858 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1APB5-1", "uniprot_ac": "A0A8V1APB5", "uniprot_id": "A0A8V1APB5_CHICK", "mass": { "chemical_mass": 64207.0, "monoisotopic_mass": 64207.0 }, "refseq": { "ac": "XP_415654", "name": "coilin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415654" }, "gene_names": [ { "name": "COIL", "type": "recommended", "evidence": [ { "id": "A0A8V1APB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ] }, { "name": "COIL", "type": "synonym", "evidence": [ { "id": "XP_415654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415654" } ] } ], "protein_names": [ { "name": "Coilin", "type": "synonym", "evidence": [ { "id": "A0A8V1APB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5/entry#names_and_taxonomy" } ] }, { "name": "coilin", "type": "synonym", "evidence": [ { "id": "XP_415654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415654" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415654.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415654" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COIL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5", "locus": { "chromosome": "18", "start_pos": 6921426, "end_pos": 6926918, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029586", "url": "https://www.ensembl.org/id/ENSGALG00010029586" } ] } } ], "crossref": [ { "id": "A0A8V1APB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1APB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "417402", "url": "https://www.ncbi.nlm.nih.gov/gene/417402", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417402", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417402", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEYKKQT", "url": "https://omabrowser.org/oma/group/CEYKKQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AKZ4", "url": "https://www.orthodb.org/?gene=A0A8V1AKZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APB5", "url": "https://www.orthodb.org/?gene=A0A8V1APB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15197", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15197", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15197:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15197:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AKZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AKZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGGAPVRLRLQFDFPPPGSPGCALCWLLLEPGQARLVTDLLSIIRHRFGFSRRARLSLFLDGALLPPTESARLVRDNDALRVTLEEIAEEGCEEADDDFYAPKDDKKRHKRRQKAQGLSRSGEEKHQREKKKNKYSPECSSGREGTSGDVSDTRKKSKKRKRREENSGTVPRPSEGKKGRADRPPKLQKAQKEERPAAKAKDGRRAALPAAKAAHGRVGGSAPLMAAKSTSKNLTAEAQKQRVGTSESSSTSSDSDSSESNVKQSKSSHRPAAAALPRDKAQTAVTAAACNQMANAEHCSKAAVSKNAKKSQSSSSDSDSSSEDERAAAAQGSTTEQVLPNSAAAAQTGPTGAPKARSSSSSSDSSDSDTIVIKKPAANAGLSNSIARNGSKQSPAGIQGPAAGLGRGRGRAVVEGNFWRGPRGRGFRGMVRGRGRGESPGFFYSYSSEGQKQRQLHEAVTNTSVPVQNAVDVPKRDYSVLPLLAAPPQVGERIAFKRLELNENYSPEVSSYKEGRIISWNADKKQIELEILSSPASQIAKEPGKFDLVYQSADGAELIEYAVPQDTKITESWDSLIEPRLIVEPPMNGSGIENGAV", "length": 600, "header": "tr|A0A8V1APB5-1|A0A8V1APB5_CHICK Isoform 1 of Coilin OS=Gallus gallus OX=9031 GN=COIL PE=1 SV=1 CANONICAL=A0A8V1APB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AKZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5/entry#A0A8V1AKZ4-1", "sequence": { "sequence": "MAAAGGAPVRLRLQFDFPPPGSPGCALCWLLLEPGQARLVTDLLSIIRHRFGFSRRARLSLFLDGALLPPTESARLVRDNDALRVTLEEIAEEGCEEADDDFYAPKDDKKRHKRRQKAQGLSRSGEEKHQREKKKNKYSPECSSGREGTSGDVSDTRKKSKKRKRREENSGTVPRPSEGKKGRADRPPKLQKAQKEERPAAKAKDGRRAALPAAKAAHGRVGGSAPLMAAKSTSKNLTAEAQKQRVGTSESSSTSSDSDSSESNVKQSKSSHRPAAAALPRDKAQTAVTAAACNQMANAEHCSKAAVSKNAKKSQSSSSDSDSSSEDERAAAAQGSTTEQVLPNSAAAAQTGPTGAPKARSSSSSSDSSDSDTIVIKKPAANAGLSNSIARNGSKQSPAGIQGPAAGLGRGRGRAVVEGNFWRGPRGRGFRGMVRGRGRGESPGFFYSYSSEGQKQRQLHEAVTNTSVPVQNAVDVPKRDYSVLPLLAAPPQVGERIAFKRLELNENYSPEVSSYKLLKSQGSLIWFTSLQMGLS", "length": 535, "header": "tr|A0A8V1AKZ4-1|A0A8V1APB5_CHICK Computationally mapped isoform of Coilin OS=Gallus gallus OX=9031 GN=COIL PE=1 SV=1 CANONICAL=A0A8V1APB5-1" }, "locus": { "chromosome": "18", "start_pos": 6926898, "end_pos": 6922343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071514.1", "url": "https://www.ensembl.org/id/ENSGALT00010071514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044204.1", "url": "https://www.ensembl.org/id/ENSGALP00010044204.1" } ] } }, { "isoform_ac": "A0A8V1APB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5/entry#A0A8V1APB5-1", "sequence": { "sequence": "MAAAGGAPVRLRLQFDFPPPGSPGCALCWLLLEPGQARLVTDLLSIIRHRFGFSRRARLSLFLDGALLPPTESARLVRDNDALRVTLEEIAEEGCEEADDDFYAPKDDKKRHKRRQKAQGLSRSGEEKHQREKKKNKYSPECSSGREGTSGDVSDTRKKSKKRKRREENSGTVPRPSEGKKGRADRPPKLQKAQKEERPAAKAKDGRRAALPAAKAAHGRVGGSAPLMAAKSTSKNLTAEAQKQRVGTSESSSTSSDSDSSESNVKQSKSSHRPAAAALPRDKAQTAVTAAACNQMANAEHCSKAAVSKNAKKSQSSSSDSDSSSEDERAAAAQGSTTEQVLPNSAAAAQTGPTGAPKARSSSSSSDSSDSDTIVIKKPAANAGLSNSIARNGSKQSPAGIQGPAAGLGRGRGRAVVEGNFWRGPRGRGFRGMVRGRGRGESPGFFYSYSSEGQKQRQLHEAVTNTSVPVQNAVDVPKRDYSVLPLLAAPPQVGERIAFKRLELNENYSPEVSSYKEGRIISWNADKKQIELEILSSPASQIAKEPGKFDLVYQSADGAELIEYAVPQDTKITESWDSLIEPRLIVEPPMNGSGIENGAV", "length": 600, "header": "tr|A0A8V1APB5-1|A0A8V1APB5_CHICK Isoform 1 of Coilin OS=Gallus gallus OX=9031 GN=COIL PE=1 SV=1 CANONICAL=A0A8V1APB5-1" }, "locus": { "chromosome": "18", "start_pos": 6926898, "end_pos": 6921806, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071516.1", "url": "https://www.ensembl.org/id/ENSGALT00010071516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044206.1", "url": "https://www.ensembl.org/id/ENSGALP00010044206.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 354, "start_aa": "Thr", "end_pos": 354, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr354", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417402", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417402", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LLE4-1", "protein_name": "Coilin", "gene_name": "Coil", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKMAASETVRVRLQFDYPPPATPHCTVFWLLVDLNRCRVVTDLISLIRQRFGFSSGALLGLYLEGGLLPPSESARLVRDNDCLRVKLEDQGLPEALIVSNGGDSNFPCRKSKKRAFKLVEDEETDQGYKYPDKYWKRQEDSGPNEKASDLETKLFPDEVRRTKNKRKSKVAGIPAEEDEEETKKKSSKRKEKCEQKKQTRASKSPKQQTHKEGGSQNCSFPRASYRSSLAKARRRSSTGAKGSPSYLSESESCPDSVSDGHCSVTTMQGVTLSEKLSAELLKDGATKTAAANRQSSKPSFTFSSGKGKASRASSSSSDSSSESEDQFLVSKNMLEGASDFLKTTGLFAGQGCSSPGLSLETPGIMGWKPSDSNRGRQAPGPNVPVPTSLGRGWGRGEDFLFGKGLRGRGIRGRGRGRGQTVSCILNRSSESQKQKQLNDILTNSSTVIQVSERLLFVSWPPFPHASYLSPVVWCGVGPPFLTSNEDTCLLQNPVETSKKDYSLLPLLAAAPQVGEKIAFKLLELTSDYSPDVSDYKEGKILSHDPETQQVDIEVLSSLPALKEPGKFDLVYHNENGTEVVEYAVTQEKRITVFWKELIDPRLIIDSSSSISSK", "length": 614 }, "evidence": [ { "id": "A0A8V1APB5", "url": "https://omabrowser.org/oma/group/A0A8V1APB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0S7K8-1", "protein_name": "Coilin", "gene_name": "coil", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATSSLNTARVRLYFDYPPPATPECRMCWLLVDLNKCRVVADLSSIIKEKFGYSRKTILDLFIEECYLPSAESIYIVRDNDSVRVKVSCPVQVNGTEAEAQNSKSKKRGREDETQTCDGLSKKQKQDNAQMNGLGPDEDEKKKKKKKKKKKKKEVKESITKPATPQKSTAALSTKTKSKSTSAVASSDKTNRTKNHKPASSSSDSSEDESQKKAPPPKPKPSKKPCVAAQKESTDSSSSDETEKLKSSIPLPITPKPSSSTSKLQTPQQRESSSSSSSSPIIKNSQAAGQSSSTTQKSLQPVSSSVPKKPQDEGESSSSDESEIELVIKKPNLQGLGLRIAGVSPGFGEAAGRGRGNAQGQERGRGRGANRGSGRGGFSRARGTPWKQNFHYSYENEERQKPEDSLTNESFILQNPPELAPKRDYATLPLLAAPPAVGQKIAFKLLELTENYTPEVSDYKEGKILAFNPQTKVTELELLSRPQAPAEPGKFDLVYQNPDGSERVEYAVTQGSQLTERWDSLLEPRLIVENAK", "length": 532 }, "evidence": [ { "id": "A0A8V1APB5", "url": "https://omabrowser.org/oma/group/A0A8V1APB5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MEL4-1", "protein_name": "Coilin", "gene_name": "COIL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESTPLRVALQSSVAATPTNRGHSFIGSRGRAPSTPLGRPVESLGFRCASSKMAASETVRLRLQFDYPPPGAPHCTSFWLLIDLNGCRVVTDLISLIRQRFGFSSGALLGLYLEGALLPPAESARLVRDNDCLRVKLEERGIAESPVTVSNGDSIRLSPRKAKKRAFKLDEDEETELDYRNSKKHWKRHENNNSEKTLDLEPKATTDQSVSKKNKRKNKAMCDAVEVDDGETEKKLPKKKEKREYKKHAKTPKSSKAQSVKEWTIQKCSPKALPARNSLVKAKRKGGMVVRTKDSPDSSSESESYHESTSDGLSNVILEVRHSSEKISTDVSKEGSSVKTTAANKVAPKTGFTSVPVKGKTSRTSSSSSDSSSESDDQCVMPKSTPECTAEFLKTVGLFVGRNCPGPSSQAPNTAGWKQSDPNSGSRTQTVLCPPPNVTLPASLGRGWGRGEDLLSWKGARGRGMRGRGRGRGHAVPYVLNRNADYQKQQQLNEMVTNSSTIIQNPIETQKKDYSLLPLLAAAPQVGEKIAFKLLELTSNYSPDVSDYKEGRILSHNPETQQVDIEILSSLPAMKEPGKFDLVYHNENGAEVVEYAVTQEKRITVLWRELIDPRLIIESPSNT", "length": 623 }, "evidence": [ { "id": "A0A8V1APB5", "url": "https://omabrowser.org/oma/group/A0A8V1APB5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P38432-1", "protein_name": "Coilin", "gene_name": "COIL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLYLEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQTAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRGHPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFKLLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVVEYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA", "length": 576 }, "evidence": [ { "id": "A0A8V1APB5", "url": "https://omabrowser.org/oma/group/A0A8V1APB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SU73-1", "protein_name": "Coilin", "gene_name": "Coil", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASETVRLRLQFDYPPPATPHCTVFWLLVDLNRCRVVTDLISLIRQRFGFSSGALLGLYLEGGLLPPAESARLVRDNDSLRVKLEDQGLPENLIVSNGGDSSFPCRKAKKRAFKLMEDEETDQGYKSLKKHCKRQEDSGQNEKASDLETKLLPDETGRTKSKKKSKVTGSPAEEDEEETKKKSSKRKEKCEPKKQTRASKSSKQQTPKEGASQNCSFPRASPRSLGKARRRSSTGLKGSSGHLSESESCPESVSDGHCSVMMQEVTFSEKLSAELLKDAPATKTAAANRQASKPGFTFSSGKGKASRTSSSSSDSSSESEDQFLVSKNMLEGASAGFLKPTGLFAGQGGSGPGLSLETPGIMGWKSSDSNRGRQAPGPPSTPVPTSLGRGWGRGEDLLFGKGLRGRGVRGRGRGRGQAVSCVFNRSSESQKQRQLNDILTNSSVVIQNPVEPPKKDYSLLPLLAAAPQVGEKIAFKLLELTSDYSPDVSDYKEGKILSHDPETQQVDIEVLSSLPALKEPGKFDLVYHNENGTEVVEYAVTQEKRITVLWRELIDPRLIIDSSGSISST", "length": 570 }, "evidence": [ { "id": "A0A8V1APB5", "url": "https://omabrowser.org/oma/group/A0A8V1APB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RWK8-1", "protein_name": "Coilin", "gene_name": "COIL", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEEKVRVRLVFEDRRILSKYQKKQGLTRSWVVLNRKCHRTISEFSDHIFHTFSLCEACPHGLSLSMEGFVLPPFESSCVLKDKDIVCVKKKKESLLEIVGEDSDENVYNAIEVEERPQIRPGEMLLANEEFQKETGGYESESEEDELEEEAEEFVPEKKASKKRKTSSKNQSTKRKKCKLDTTEESPDERENTAVVSNVVKKKKKKKSLDVQSANNDEQNNDSTKPMTKSKRSSQQEESKEHNDLCQLSAETKKTPSRSARRKKAKRQWLREKTKLEKEELLQTQLVVAPSQKPVITIDHQATKEKHCETLENQQAEEVSDGFGDEVVPVEVRPGHIRFKPLAGTDEASLDSEPLVENVLWNGNMTKKKGQKWGTEKSGFSKRYAQDFNEDATTQPAEAETLANCPIDYEQLVAYTGSVKKGDVIAYRLIELTSSWTPEVSSFRVGKISYYDPDSKMVTLMPVQEFPIEKKTEEDDDFCMQPDTSLYKEDGSLEIEFSALLDVRSVKTSSSDSAEVAKSALPEPDQSAKKPKLSANKELQTPAKENGEVSPWEELSEALSAKKAALSQANNGWNKKGSSSGGSWSYKALRGSAMGPVMNYLRSQKEI", "length": 608 }, "evidence": [ { "id": "A0A8V1APB5", "url": "https://omabrowser.org/oma/group/A0A8V1APB5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" }, { "id": "PF15862", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15862" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coilin N-terminal", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 137, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1APB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APB5" }, { "id": "PF23086", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coilin tudor", "eco_id": "ECO_0000259", "start_pos": 479, "end_pos": 574, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 289, 354 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 507, "end_pos": 509 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMG8-1", "uniprot_ac": "A0A8V1AMG8", "uniprot_id": "A0A8V1AMG8_CHICK", "mass": { "chemical_mass": 152710.0, "monoisotopic_mass": 152710.0 }, "refseq": {}, "gene_names": [ { "name": "SYNRG", "type": "recommended", "evidence": [ { "id": "A0A8V1AMG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8" } ] } ], "protein_names": [ { "name": "Synergin gamma", "type": "synonym", "evidence": [ { "id": "A0A8V1AMG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYNRG", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8", "locus": { "chromosome": "19", "start_pos": 9082489, "end_pos": 9116615, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029935", "url": "https://www.ensembl.org/id/ENSGALG00010029935" } ] } } ], "crossref": [ { "id": "cd00052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417658", "url": "https://www.ncbi.nlm.nih.gov/gene/417658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFN3", "url": "https://www.orthodb.org/?gene=A0A8V1AFN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL18", "url": "https://www.orthodb.org/?gene=A0A8V1AL18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMG8", "url": "https://www.orthodb.org/?gene=A0A8V1AMG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMH3", "url": "https://www.orthodb.org/?gene=A0A8V1AMH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP04", "url": "https://www.orthodb.org/?gene=A0A8V1AP04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQA9", "url": "https://www.orthodb.org/?gene=A0A8V1AQA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15463", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15463", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15463:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15463:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26996", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26996", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP04", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGRGLCVILPMSPLKCTAAGGGSNCSVRTVAGGAGALRRLLSSTGVHVPFSPSSSSFMFPVAGTLGPPQGMIPMQQQGFPMVPVMQSNMPGMMGMNYGSQIPPGPMAMQGGMPLGPMPATGMPYMGQASFIGMRPAAPQYTPDMQKQFAEEQQKRFEHQQKFLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDHSTSSSHSAVSVSHSSFLDDEEFSDFIQGPTESPKVVPQSTSQPFQPFHSATGAGQLLSEKAVVQPLPPAQTPVLSILHGTAGHVPYFPTSASSLNIHKTGSSLEEKVLDNGSNESEQEQTKLKTSEVGHKASAPGQAHPSLAINDWALVGGHESGTTAAEVHKASEQNIAIEECGVGVFPSQDPIQQMMPPWIYNDSLVPELYKKILETTLTPAGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAVTQRGIPAVSPDMLNQFPAAPVPTLSGFPMPLPAAVSQQPLLPTGPPVSMPLSIGPPVMGMGITAAAPAGGAAAPPAGAFVPSYPPSQVVKPEDDDFQEFQDASKSGSLDDSFTDFQGDGAGSSKAASSQHRSSVPSLLMPLPGNKTLSSTDKYAVFKGIAADKPESTATFADSGDKYSAFRELEQPSESKYGGDNLAEFKAAGTDDGFTDFKTADSISPLEPPTKDKTFPTSFPSLPVQSKQQTQAKTSLNLADLDLFSSTGENKQLSFPPAFNASKPSSFPPPPSTTAQPAPSKSSSLADEFGEFNLFGEFSNSASASGQDDFADFMAFNNSSGFSEQKPDDKYNALKAETSPVPQPGSSASTGRSVQNSATAATPTKYDIFKQLSLEGSGAGFEETKDSTLSSVKSDDDFADFHSNKFSSTCNSTDKSLVDKVAAFKQAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLTDVEGDLKHVMSDSSLDLPTVSGQHPPAADIDELKCAPFGSYNSGSAVSSLASYDWSDKDDIHQGKKFSFAQASGSGSSAATSVLQKKETLFGSSENITMTTVSKVTTFSSEDALQDVSFAAFANFKDSGPISSGPSDDDNGDFGEFARPSSEARDAAADPNQEADFLTGGISSEVQRESTDDFGEFQSEKPKISKFDFLVATSQGKVKSSEEMIKSELATFDLSVQGSHKRSLSLGDREISRSSPLSALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEESERYAYEWQRCLESALQVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLISFMSLAALTPDENSLDFSSCMLRPGIKNAQDLACGVCLLNVDSRSKAFNSETDNFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1432, "header": "tr|A0A8V1AMG8-1|A0A8V1AMG8_CHICK Isoform 1 of Synergin gamma OS=Gallus gallus OX=9031 GN=SYNRG PE=1 SV=1 CANONICAL=A0A8V1AMG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8/entry#A0A8V1AFN3-1", "sequence": { "sequence": "MFCASSFMFPVAGTLGPPQGMIPMQQQGFPMVPVMQSNMPGMMGMNYGSQIPPGPMAMQGGMPLGPMPATGMPYMGQASFIGMRPAAPQYTPDMQKQFAEEQQKRFEHQQKFLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDHSTSSSHSAVSVSHSSFLDDEEFSDFIQGPTESPKVVPQSTSQPFQPFHSATGAGQLLSEKAVVQPLPPAQTPVLSILHGTAGHVPYFPTSASSLNIHKTGSSLEEKVLDNGSNESEQEQTKLKTSEVGHKASAPGQAHPSLAINDWALVGGHESGTTAAEVHKASEQNIAIEECGVGVFPSQDPIQQMMPPWIYNDSLVPELYKKILETTLTPAGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAVTQRGIPAVSPDMLNQFPAAPVPTLSGFPMPLPAAVSQQPLLPTGPPVSMPLSIGPPVMGMGITAAAPAGGAAAPPAGAFVPSYPPSQVVKPEDDDFQEFQDASKSGSLDDSFTDFQGDGAGSSKAASSQHRSSVPSLLMPLPGNKTLSSTDKYAVFKGIAADKPESTATFADSGDKYSAFRELEQPSESKYGGDNLAEFKAAGTDDGFTDFKTADSISPLEPPTKDKTFPTSFPSLPVQSKQQTQAKTSLNLADLDLFSSTGENKQLSFPPAFNASKPSSFPPPPSTTAQPAPSKSSSLADEFGEFNLFGEFSNSASASGQDDFADFMAFNNSSGFSEQKPDDKYNALKAETSPVPQPGSSASTGRSVQNSATAATPTKYDIFKQLSLEGSGAGFEETKDSTLSSVKSDDDFADFHSNKFSSTCNSTDKSLVDKVAAFKQAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLTDVEGDLKHVMSDSSLDLPTVSGQHPPAADIDELKCAPFGSYNSGSAVSSLASYDWSDKDDIHQGKKFSFAQASGSGSSAATSVLQKKETLFGSSENITMTTVSKVTTFSSEDALQDVSFAAFANFKDSGPISSGPSDDDNGDFGEFARPSSEARDAAADPNQEADFLTGGISSEVQRESTDDFGEFQSEKPKISKFDFLVATSQGKVKSSEEMIKSELATFDLSVQGSHKRSLSLGDREISRSSPLSALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEESERYAYEWQRCLESALQVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLISFMSLAALTPDENSLDFSSCMLRPGIKNAQDLACGVCLLNVDSRSKKEEKPVEELPKKAFNSETDNFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1393, "header": "tr|A0A8V1AFN3-1|A0A8V1AFN3_CHICK Computationally mapped isoform of Synergin gamma OS=Gallus gallus OX=9031 GN=SYNRG PE=1 SV=1 CANONICAL=A0A8V1AMG8-1" }, "locus": { "chromosome": "19", "start_pos": 9114864, "end_pos": 9083493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072361.1", "url": "https://www.ensembl.org/id/ENSGALT00010072361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044828.1", "url": "https://www.ensembl.org/id/ENSGALP00010044828.1" } ] } }, { "isoform_ac": "A0A8V1AL18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8/entry#A0A8V1AL18-1", "sequence": { "sequence": "MFPVAGTLGPPQGMIPMQQQGFPMVPVMQSNMPGMMGMNYGSQIPPGPMAMQGGMPLGPMPATGMPYMGQASFIGMRPAAPQYTPDMQKQFAEEQQKRFEHQQKFLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDHSTSSSHSAVSVSHSSFLDDEEFSDFIQGPTESPKVVPQSTSQPFQPFHSATGAGQLLSEKAVVQPLPPAQTPVLSILHGTAGHVPYFPTSASSLNIHKTGSSLEEKVLDNGSNESEQEQTKLKTSEVGHKASAPGQAHPSLAINDWALVGGHESGTTAAEVHKASEQNIAIEECGVGVFPSQDPIQQMMPPWIYNDSLVPELYKKILETTLTPAGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAVTQRGIPAVSPDMLNQFPAAPVPTLSGFPMPLPAAVSQQPLLPTGPPVSMPLSIGPPVMGMGITAAAPAGGAAAPPAGAFVPSYPPSQVVKPEDDDFQEFQDASKSGSLDDSFTDFQGDGAGSSKAASSQHRSSVPSLLMPLPGNKTLSSTDKYAVFKGIAADKPESTATFADSGDKYSAFRELEQPSESKYGGDNLAEFKAAGTDDGFTDFKTADSISPLEPPTKDKTFPTSFPSLPVQSKQQTQAKTSLNLADLDLFSSTGENKQLSFPPAFNASKPSSFPPPPSTTAQPAPSKSSSLADEFGEFNLFGEFSNSASASGQDDFADFMAFNNSSGFSEQKPDDKYNALKAETSPVPQPGSSASTGRSVQNSATAATPTKYDIFKQLSLEGSGAGFEETKDSTLSSVKSDDDFADFHSNKFSSTCNSTDKSLVDKVAAFKQAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLTDVEGDLKHVMSDSSLDLPTVSGQHPPAADIDELKCAPFGSYNSGSAVSSLASYDWSDKDDIHQGKKFSFAQASGSGSSAATSVLQKKETLFGSSENITMTTVSKVTTFSSEDALQDVSFAAFANFKDSGPISSGPSDDDNGDFGEFARPSSEARDAAADPNQEADFLTGGISSEVQRESTDDFGEFQSEKPKISKFDFLVATSQGKVKSSEEMIKSELATFDLSVQGSHKRSLSLGDREISRSSPLSALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEESERYAYEWQRCLESALQVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLISFMSLAALTPDENSLDFSSCMLRPGIKNAQDLACGVCLLNVDSRSKKEEKPVEELPKKAFNSETDNFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1386, "header": "tr|A0A8V1AL18-1|A0A8V1AMG8_CHICK Computationally mapped isoform of Synergin gamma OS=Gallus gallus OX=9031 GN=SYNRG PE=1 SV=1 CANONICAL=A0A8V1AMG8-1" }, "locus": { "chromosome": "19", "start_pos": 9112187, "end_pos": 9083493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072358.1", "url": "https://www.ensembl.org/id/ENSGALT00010072358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044825.1", "url": "https://www.ensembl.org/id/ENSGALP00010044825.1" } ] } }, { "isoform_ac": "A0A8V1AMG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8/entry#A0A8V1AMG8-1", "sequence": { "sequence": "MCGRGLCVILPMSPLKCTAAGGGSNCSVRTVAGGAGALRRLLSSTGVHVPFSPSSSSFMFPVAGTLGPPQGMIPMQQQGFPMVPVMQSNMPGMMGMNYGSQIPPGPMAMQGGMPLGPMPATGMPYMGQASFIGMRPAAPQYTPDMQKQFAEEQQKRFEHQQKFLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDHSTSSSHSAVSVSHSSFLDDEEFSDFIQGPTESPKVVPQSTSQPFQPFHSATGAGQLLSEKAVVQPLPPAQTPVLSILHGTAGHVPYFPTSASSLNIHKTGSSLEEKVLDNGSNESEQEQTKLKTSEVGHKASAPGQAHPSLAINDWALVGGHESGTTAAEVHKASEQNIAIEECGVGVFPSQDPIQQMMPPWIYNDSLVPELYKKILETTLTPAGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAVTQRGIPAVSPDMLNQFPAAPVPTLSGFPMPLPAAVSQQPLLPTGPPVSMPLSIGPPVMGMGITAAAPAGGAAAPPAGAFVPSYPPSQVVKPEDDDFQEFQDASKSGSLDDSFTDFQGDGAGSSKAASSQHRSSVPSLLMPLPGNKTLSSTDKYAVFKGIAADKPESTATFADSGDKYSAFRELEQPSESKYGGDNLAEFKAAGTDDGFTDFKTADSISPLEPPTKDKTFPTSFPSLPVQSKQQTQAKTSLNLADLDLFSSTGENKQLSFPPAFNASKPSSFPPPPSTTAQPAPSKSSSLADEFGEFNLFGEFSNSASASGQDDFADFMAFNNSSGFSEQKPDDKYNALKAETSPVPQPGSSASTGRSVQNSATAATPTKYDIFKQLSLEGSGAGFEETKDSTLSSVKSDDDFADFHSNKFSSTCNSTDKSLVDKVAAFKQAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLTDVEGDLKHVMSDSSLDLPTVSGQHPPAADIDELKCAPFGSYNSGSAVSSLASYDWSDKDDIHQGKKFSFAQASGSGSSAATSVLQKKETLFGSSENITMTTVSKVTTFSSEDALQDVSFAAFANFKDSGPISSGPSDDDNGDFGEFARPSSEARDAAADPNQEADFLTGGISSEVQRESTDDFGEFQSEKPKISKFDFLVATSQGKVKSSEEMIKSELATFDLSVQGSHKRSLSLGDREISRSSPLSALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEESERYAYEWQRCLESALQVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLISFMSLAALTPDENSLDFSSCMLRPGIKNAQDLACGVCLLNVDSRSKAFNSETDNFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1432, "header": "tr|A0A8V1AMG8-1|A0A8V1AMG8_CHICK Isoform 1 of Synergin gamma OS=Gallus gallus OX=9031 GN=SYNRG PE=1 SV=1 CANONICAL=A0A8V1AMG8-1" }, "locus": { "chromosome": "19", "start_pos": 9112361, "end_pos": 9083493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072355.1", "url": "https://www.ensembl.org/id/ENSGALT00010072355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044822.1", "url": "https://www.ensembl.org/id/ENSGALP00010044822.1" } ] } }, { "isoform_ac": "A0A8V1AMH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8/entry#A0A8V1AMH3-1", "sequence": { "sequence": "MCGRGLCVILPMSPLKCTAAGGGSNCSVRTVAGGAGALRRLLSSTGVHVPFSPSSSSFMFPVAGTLGPPQGMIPMQQQGFPMVPVMQSNMPGMMGMNYGSQIPPGPMAMQGGMPLGPMPATGMPYMGQASFIGMRPAAPQYTPDMQKQFAEEQQKRFEHQQKFLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPGSSLEEKVLDNGSNESEQEQTKLKTSEVGHKASAPGQAHPSLAINDWALVGGHESGTTAAEVHKASEQNIAIEECGVGVFPSQDPIQQMMPPWIYNDSLVPELYKKILETTLTPAGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAVTQRGIPAVSPDMLNQFPAAPVPTLSGFPMPLPAAVSQQPLLPTGPPVSMPLSIGPPVMGMGITAAAPAGGAAAPPAGAFVPSYPPSQVVKPEDDDFQEFQDASKSGSLDDSFTDFQGDGAGSSKAASSQHRSSVPSLLMPLPGNKTLSSTDKYAVFKGIAADKPESTATFADSGDKYSAFRELEQPSESKYGGDNLAEFKAAGTDDGFTDFKTADSISPLEPPTKDKTFPTSFPSLPVQSKQQTQAKTSLNLADLDLFSSTGENKQLSFPPAFNASKPSSFPPPPSTTAQPAPSKSSSLADEFGEFNLFGEFSNSASASGQDDFADFMAFNNSSGFSEQKPDDKYNALKAETSPVPQPGSSASTGRSVQNSATAATPTKYDIFKQLSLEGSGAGFEETKDSTLSSVKSDDDFADFHSNKFSSTCNSTDKSLVDKVAAFKQAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLTDVEGDLKHVMSDSSLDLPTVSGQHPPAADIDELKCAPFGSYNSGSAVSSLASYDWSDKDDIHQGKKFSFAQASGSGSSAATSVLQKKETLFGSSENITMTTVSKVTTFSSEDALQDVSFAAFANFKDSGPISSGPSDDDNGDFGEFARPSSEARDAAADPNQEADFLTGGISSEVQRESTDDFGEFQSEKPKISKFDFLVATSQGKVKSSEEMIKSELATFDLSVQGSHKRSLSLGDREISRSSPLSALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEESERYAYEWQRCLESALQVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLISFMSLAALTPDENSLDFSSCMLRPGIKNAQDLACGVCLLNVDSRSKKEEKPVEELPKKAFNSETDNFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1343, "header": "tr|A0A8V1AMH3-1|A0A8V1AMH3_CHICK Computationally mapped isoform of Synergin gamma OS=Gallus gallus OX=9031 GN=SYNRG PE=1 SV=1 CANONICAL=A0A8V1AMG8-1" }, "locus": { "chromosome": "19", "start_pos": 9112361, "end_pos": 9083493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072360.1", "url": "https://www.ensembl.org/id/ENSGALT00010072360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044827.1", "url": "https://www.ensembl.org/id/ENSGALP00010044827.1" } ] } }, { "isoform_ac": "A0A8V1AP04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8/entry#A0A8V1AP04-1", "sequence": { "sequence": "MCGRGLCVILPMSPLKCTAAGGGSNCSVRTVAGGAGALRRLLSSTGVHVPFSPSSSSFMFPVAGTLGPPQGMIPMQQQGFPMVPVMQSNMPGMMGMNYGSQIPPGPMAMQGGMPLGPMPATGMPYMGQASFIGMRPAAPQYTPDMQKQFAEEQQKRFEHQQKFLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDHSTSSSHSAVSVSHSSFLDDEEFSDFIQGPTESPKVVPQSTSQPFQPFHSATGAGQLLSEKAVVQPLPPAQTPVLSILHGTAGHVPYFPTSASSLNIHKTGVGVFPSQDPIQQMMPPWIYNDSLVPELYKKILETTLTPAGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAVTQRGIPAVSPDMLNQFPAAPVPTLSGFPMPLPAAVSQQPLLPTGPPVSMPLSIGPPVMGMGITAAAPAGGAAAPPAGAFVPSYPPSQVVKPEDDDFQEFQDASKSGSLDDSFTDFQGDGAGSSKAASSQHRSSVPSLLMPLPGNKTLSSTDKYAVFKGIAADKPESTATFADSGDKYSAFRELEQPSESKYGGDNLAEFKAAGTDDGFTDFKTADSISPLEPPTKDKTFPTSFPSLPVQSKQQTQAKTSLNLADLDLFSSTGENKQLSFPPAFNASKPSSFPPPPSTTAQPAPSKSSSLADEFGEFNLFGEFSNSASASGQDDFADFMAFNNSSGFSEQKPDDKYNALKAETSPVPQPGSSASTGRSVQNSATAATPTKYDIFKQLSLEGSGAGFEETKDSTLSSVKSDDDFADFHSNKFSSTCNSTDKSLVDKVAAFKQAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLTDVEGDLKHVMSDSSLDLPTVSGQHPPAADIDELKCAPFGSYNSGSAVSSLASYDWSDKDDIHQGKKFSFAQASGSGSSAATSVLQKKETLFGSSENITMTTVSKVTTFSSEDALQDVSFAAFANFKDSGPISSGPSDDDNGDFGEFARPSSEARDAAADPNQEADFLTGGISSEVQRESTDDFGEFQSEKPKISKFDFLVATSQGKVKSSEEMIKSELATFDLSVQGSHKRSLSLGDREISRSSPLSALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEESERYAYEWQRCLESALQVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLISFMSLAALTPDENSLDFSSCMLRPGIKNAQDLACGVCLLNVDSRSKKEEKPVEELPKKAFNSETDNFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1369, "header": "tr|A0A8V1AP04-1|A0A8V1AP04_CHICK Computationally mapped isoform of Synergin gamma OS=Gallus gallus OX=9031 GN=SYNRG PE=1 SV=1 CANONICAL=A0A8V1AMG8-1" }, "locus": { "chromosome": "19", "start_pos": 9112361, "end_pos": 9083493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072359.1", "url": "https://www.ensembl.org/id/ENSGALT00010072359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044826.1", "url": "https://www.ensembl.org/id/ENSGALP00010044826.1" } ] } }, { "isoform_ac": "A0A8V1AQA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8/entry#A0A8V1AQA9-1", "sequence": { "sequence": "MSFMFPVAGTLGPPQGMIPMQQQGFPMVPVMQSNMPGMMGMNYGSQIPPGPMAMQGGMPLGPMPATGMPYMGQASFIGMRPAAPQYTPDMQKQFAEEQQKRFEHQQKFLEEERKRRQFEEQKQKLRLLSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDHSTSSSHSAVSVSHSSFLDDEEFSDFIQGPTESPKVVPQSTSQPFQPFHSATGAGQLLSEKAVVQPLPPAQTPVLSILHGTAGHVPYFPTSASSLNIHKTGSSLEEKVLDNGSNESEQEQTKLKTSEVGHKASAPGQAHPSLAINDWALVGGHESGTTAAEVHKASEQNIAIEECGVGVFPSQDPIQQMMPPWIYNDSLVPELYKKILETTLTPAGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYAVLAMIAVTQRGIPAVSPDMLNQFPAAPVPTLSGFPMPLPAAVSQQPLLPTGPPVSMPLSIGPPVMGMGITAAAPAGGAAAPPAGAFVPSYPPSQVVKPEDDDFQEFQDASKSGSLDDSFTDFQGDGAGSSKAASSQHRSSVPSLLMPLPGNKTLSSTDKYAVFKGIAADKPESTATFADSGDKYSAFRELEQPSESKYGGDNLAEFKAAGTDDGFTDFKTADSISPLEPPTKDKTFPTSFPSLPVQSKQQTQAKTSLNLADLDLFSSTGENKQLSFPPAFNASKPSSFPPPPSTTAQPAPSKSSSLADEFGEFNLFGEFSNSASASGQDDFADFMAFNNSSGFSEQKPDDKYNALKAETSPVPQPGSSASTGRSVQNSATAATPTKYDIFKQLSLEGSGAGFEETKDSTLSSVKSDDDFADFHSNKFSSTCNSTDKSLVDKVAAFKQAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLTDVEGDLKHVMSDSSLDLPTVSGQHPPAADIDELKCAPFGSYNSGSAVSSLASYDWSDKDDIHQGKKFSFAQASGSGSSAATSVLQKKETLFGSSENITMTTVSKVTTFSSEDALQDVSFAAFANFKDSGPISSGPSDDDNGDFGEFARPSSEARDAAADPNQEADFLTGGISSEVQRESTDDFGEFQSEKPKISKFDFLVATSQGKVKSSEEMIKSELATFDLSVQGSHKRSLSLGDREISRSSPLSALEQPFRDRSNTLSEKPALPVIRDKYKDLTGEVEESERYAYEWQRCLESALQVIKKANDTLNGISSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLISFMSLAALTPDENSLDFSSCMLRPGIKNAQDLACGVCLLNVDSRSKKEEKPVEELPKKAFNSETDNFKLAYGGHQYHASCANFWINCVEPKPPGLILPDLL", "length": 1389, "header": "tr|A0A8V1AQA9-1|A0A8V1AQA9_CHICK Computationally mapped isoform of Synergin gamma OS=Gallus gallus OX=9031 GN=SYNRG PE=1 SV=1 CANONICAL=A0A8V1AMG8-1" }, "locus": { "chromosome": "19", "start_pos": 9116418, "end_pos": 9083493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072362.1", "url": "https://www.ensembl.org/id/ENSGALT00010072362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044829.1", "url": "https://www.ensembl.org/id/ENSGALP00010044829.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "clathrin coat of trans-Golgi network vesicle", "id": "GO:0030130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" }, { "start_pos": 917, "end_pos": 919, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG8" }, { "id": "PS50031", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EH", "eco_id": "ECO_0000259", "start_pos": 423, "end_pos": 505, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1276, "end_pos": 1278 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 636, "end_pos": 638 }, { "start_pos": 766, "end_pos": 768 }, { "start_pos": 823, "end_pos": 825 }, { "start_pos": 824, "end_pos": 826 }, { "start_pos": 917, "end_pos": 919 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { 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"url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERPINF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH6", "locus": { "chromosome": "19", "start_pos": 5889132, "end_pos": 5880503, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029936", "url": "https://www.ensembl.org/id/ENSGALG00010029936" } ] } } ], "crossref": [ { "id": "A0A8V1AMH6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMH6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02053", "url": 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This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151376.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151376" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC427816", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15", "locus": {} } ], "crossref": [ { "id": "A0A8V1AP15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP15", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427816", "url": "https://www.ncbi.nlm.nih.gov/gene/427816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427816", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427816", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKGNCKS", "url": "https://omabrowser.org/oma/group/CKGNCKS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL29", "url": "https://www.orthodb.org/?gene=A0A8V1AL29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP15", "url": "https://www.orthodb.org/?gene=A0A8V1AP15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151376", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AL29", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATQCLCLLILTSLLALAAPLVFDIKNLHLLNGTMDEIMNIHPEPVQPDEGDHHVRQVRDIAPRPPAAHGWPKDCSEIPPGSHSGVYIIQPKGLHQLVVYCEMNTTGGGWTVIQRNQKDTAVTWAESWSTYKYGFGNVRSDYWLGTEYIHQIAKQKVYQVRFVISDNANNIKFADYNLFSVEDEAHGYRLRLGSYAGTAGDAMTSDNPSTMHDNMKFSTKDRDQDNYSKNCAYSYEGGWWFSSCYSVRLNFKGGMTWGSLCKGDCKSSLILIKPAPYC", "length": 278, "header": "tr|A0A8V1AP15-1|A0A8V1AP15_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC427816 PE=4 SV=1 CANONICAL=A0A8V1AP15-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AL29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15/entry#A0A8V1AL29-1", "sequence": { "sequence": "MATQCLCLLILTSLLALAAPLVFDIKNLHLLNGTMDEIMNIHPEPVQPGWPKDCSEIPPGSHSGVYIIQPKGLHQLVVYCEMNTTGGGWTVIQRNQKDTAVTWAESWSTYKYGFGNVRSDYWLGTEYIHQIAKQKVYQVRFVISDNANNIKFADYNLFSVEDEAHGYRLRLGSYAGTAGDAMTSDNPSTMHDNMKFSTKDRDQDNYSKNCAYSYEGGWWFSSCYSVRLNFKGGMTWGSLCKGDCKSSLILIKPAPYC", "length": 257, "header": "tr|A0A8V1AL29-1|A0A8V1AP15_CHICK Computationally mapped isoform of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC427816 PE=4 SV=1 CANONICAL=A0A8V1AP15-1" }, "locus": { "chromosome": "19", "start_pos": 608936, "end_pos": 605045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072373.1", "url": "https://www.ensembl.org/id/ENSGALT00010072373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044840.1", "url": "https://www.ensembl.org/id/ENSGALP00010044840.1" } ] } }, { "isoform_ac": "A0A8V1AP15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15/entry#A0A8V1AP15-1", "sequence": { "sequence": "MATQCLCLLILTSLLALAAPLVFDIKNLHLLNGTMDEIMNIHPEPVQPDEGDHHVRQVRDIAPRPPAAHGWPKDCSEIPPGSHSGVYIIQPKGLHQLVVYCEMNTTGGGWTVIQRNQKDTAVTWAESWSTYKYGFGNVRSDYWLGTEYIHQIAKQKVYQVRFVISDNANNIKFADYNLFSVEDEAHGYRLRLGSYAGTAGDAMTSDNPSTMHDNMKFSTKDRDQDNYSKNCAYSYEGGWWFSSCYSVRLNFKGGMTWGSLCKGDCKSSLILIKPAPYC", "length": 278, "header": "tr|A0A8V1AP15-1|A0A8V1AP15_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC427816 PE=4 SV=1 CANONICAL=A0A8V1AP15-1" }, "locus": { "chromosome": "19", "start_pos": 608936, "end_pos": 605045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072374.1", "url": "https://www.ensembl.org/id/ENSGALT00010072374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044841.1", "url": "https://www.ensembl.org/id/ENSGALP00010044841.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427816", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427816", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AP15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP15" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL54-1", "uniprot_ac": "A0A8V1AL54", "uniprot_id": "A0A8V1AL54_CHICK", "mass": { "chemical_mass": 58936.0, "monoisotopic_mass": 58936.0 }, "refseq": { "ac": "XP_004946305", "name": "G-protein coupled receptor family C group 5 member C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946305" }, "gene_names": [ { "name": "GPRC5C", "type": "recommended", "evidence": [ { "id": "A0A8V1AL54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ] }, { "name": "GPRC5C", "type": "synonym", "evidence": [ { "id": "XP_004946305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946305" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor class C group 5 member C", "type": "synonym", "evidence": [ { "id": "A0A8V1AL54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor family C group 5 member C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004946305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946305" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946305.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946305" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPRC5C", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54", "locus": { "chromosome": "18", "start_pos": 9771197, "end_pos": 9765662, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010030106", "url": "https://www.ensembl.org/id/ENSGALG00010030106" } ] } } ], "crossref": [ { "id": "A0A8V1AL54", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL54", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15277", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15277", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427814", "url": "https://www.ncbi.nlm.nih.gov/gene/427814", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427814", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427814", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FDMVIPR", "url": "https://omabrowser.org/oma/group/FDMVIPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFR9", "url": "https://www.orthodb.org/?gene=A0A8V1AFR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL54", "url": "https://www.orthodb.org/?gene=A0A8V1AL54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQC9", "url": "https://www.orthodb.org/?gene=A0A8V1AQC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14511:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14511:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946305", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPACPCFQNGPTPALLRSLAAVPGCAERCGAGRHPAVLPWRAQSAARRGTRAGRCRRSRRARHRTPQRGAARRPTRPTAGCCRRTYKNSSRDTAGVCGVGWSSRVRGAPLGTHLPCRMGAAVPAAACVLLALLPMGRAQNTPPSGCGQDLSSLYYNLCDLSAAWGIVLEAAASLGAVTSFVLTIVLVASLPFVQDPQKKSLVATQAFFLLGTFGLFCLTFDFIVGPDFSTCTSRRFLFGVLFALCFSCLLAHAVALNFLARRNRGPRGWVTLAVALLLALVEVIINAEWLIITVARQERGPVDPCELADADFVMALIYVMVLLVAAFGTAWPALCGRYTRWRKHGAFILATSGLSMAIWVAWTAMYLYGNQHVGKKPIWDDPTLAIALVSNAYAFILLYVIPEVTHVTRRSSEQGYEDDVYPTRGVGYETILKEQKSQSMFVENKAFSMDEPSFAKKPVSPYSGYNGQLLTSVYQPTEMALMHKGTSEGPYDVILPRATAASSASSTLRAEDAFAVQARHAAAQRDARGSQVLSPYSRNRW", "length": 542, "header": "tr|A0A8V1AL54-1|A0A8V1AL54_CHICK Isoform 1 of G protein-coupled receptor class C group 5 member C OS=Gallus gallus OX=9031 GN=GPRC5C PE=1 SV=1 CANONICAL=A0A8V1AL54-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54/entry#A0A8V1AFR9-1", "sequence": { "sequence": "MPCHAVPCHVRLWLRVTRSVGMHGQTRDPWWVSARSHRREVDQERQKGERAVMQSRASMQPQVSPSVSSLPSPDPCSAPPGGPQAQCCVQARRVRGAPLGTHLPCRMGAAVPAAACVLLALLPMGRAQNTPPSGCGQDLSSLYYNLCDLSAAWGIVLEAAASLGAVTSFVLTIVLVASLPFVQDPQKKSLVATQAFFLLGTFGLFCLTFDFIVGPDFSTCTSRRFLFGVLFALCFSCLLAHAVALNFLARRNRGPRGWVTLAVALLLALVEVIINAEWLIITVARQERGPVDPCELADADFVMALIYVMVLLVAAFGTAWPALCGRYTRWRKHGAFILATSGLSMAIWVAWTAMYLYGNQHVGKKPIWDDPTLAIALVSNAYAFILLYVIPEVTHVTRRSSEQGYEDDVYPTRGVGYETILKEQKSQSMFVENKAFSMDEPSFAKKPVSPYSGYNGQLLTSVYQPTEMALMHKGTSEGPYDVILPRATAASSASSTLRAEDAFAVQARHAAAQRDARGSQVLSPYSRNRW", "length": 530, "header": "tr|A0A8V1AFR9-1|A0A8V1AFR9_CHICK Computationally mapped isoform of G protein-coupled receptor class C group 5 member C OS=Gallus gallus OX=9031 GN=GPRC5C PE=1 SV=1 CANONICAL=A0A8V1AL54-1" }, "locus": { "chromosome": "18", "start_pos": 9770626, "end_pos": 9767978, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072681.1", "url": "https://www.ensembl.org/id/ENSGALT00010072681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044868.1", "url": "https://www.ensembl.org/id/ENSGALP00010044868.1" } ] } }, { "isoform_ac": "A0A8V1AL54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54/entry#A0A8V1AL54-1", "sequence": { "sequence": "MRPACPCFQNGPTPALLRSLAAVPGCAERCGAGRHPAVLPWRAQSAARRGTRAGRCRRSRRARHRTPQRGAARRPTRPTAGCCRRTYKNSSRDTAGVCGVGWSSRVRGAPLGTHLPCRMGAAVPAAACVLLALLPMGRAQNTPPSGCGQDLSSLYYNLCDLSAAWGIVLEAAASLGAVTSFVLTIVLVASLPFVQDPQKKSLVATQAFFLLGTFGLFCLTFDFIVGPDFSTCTSRRFLFGVLFALCFSCLLAHAVALNFLARRNRGPRGWVTLAVALLLALVEVIINAEWLIITVARQERGPVDPCELADADFVMALIYVMVLLVAAFGTAWPALCGRYTRWRKHGAFILATSGLSMAIWVAWTAMYLYGNQHVGKKPIWDDPTLAIALVSNAYAFILLYVIPEVTHVTRRSSEQGYEDDVYPTRGVGYETILKEQKSQSMFVENKAFSMDEPSFAKKPVSPYSGYNGQLLTSVYQPTEMALMHKGTSEGPYDVILPRATAASSASSTLRAEDAFAVQARHAAAQRDARGSQVLSPYSRNRW", "length": 542, "header": "tr|A0A8V1AL54-1|A0A8V1AL54_CHICK Isoform 1 of G protein-coupled receptor class C group 5 member C OS=Gallus gallus OX=9031 GN=GPRC5C PE=1 SV=1 CANONICAL=A0A8V1AL54-1" }, "locus": { "chromosome": "18", "start_pos": 9770626, "end_pos": 9765861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072683.1", "url": "https://www.ensembl.org/id/ENSGALT00010072683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044870.1", "url": "https://www.ensembl.org/id/ENSGALP00010044870.1" } ] } }, { "isoform_ac": "A0A8V1AQC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54/entry#A0A8V1AQC9-1", "sequence": { "sequence": "MLLRHGVLRPRRPTELRPPPNSLHRCSEWALCSLPPGARSSRWGGRSPLLSTCSPAPVLRVPGAARVRGAPLGTHLPCRMGAAVPAAACVLLALLPMGRAQNTPPSGCGQDLSSLYYNLCDLSAAWGIVLEAAASLGAVTSFVLTIVLVASLPFVQDPQKKSLVATQAFFLLGTFGLFCLTFDFIVGPDFSTCTSRRFLFGVLFALCFSCLLAHAVALNFLARRNRGPRGWVTLAVALLLALVEVIINAEWLIITVARQERGPVDPCELADADFVMALIYVMVLLVAAFGTAWPALCGRYTRWRKHGAFILATSGLSMAIWVAWTAMYLYGNQHVGKKPIWDDPTLAIALVSNAYAFILLYVIPEVTHVTRRSSEQGYEDDVYPTRGVGYETILKEQKSQSMFVENKAFSMDEPSFAKKPVSPYSGYNGQLLTSVYQPTEMALMHKGTSEGPYDVILPRATAASSASSTLRAEDAFAVQARHAAAQRDARGSQVLSPYSRNRW", "length": 503, "header": "tr|A0A8V1AQC9-1|A0A8V1AQC9_CHICK Computationally mapped isoform of G protein-coupled receptor class C group 5 member C OS=Gallus gallus OX=9031 GN=GPRC5C PE=1 SV=1 CANONICAL=A0A8V1AL54-1" }, "locus": { "chromosome": "18", "start_pos": 9770626, "end_pos": 9767007, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072682.1", "url": "https://www.ensembl.org/id/ENSGALT00010072682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044869.1", "url": "https://www.ensembl.org/id/ENSGALP00010044869.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427814", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427814", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MJL6-1", "protein_name": "G protein-coupled receptor class C group 5 member C", "gene_name": "GPRC5C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHRRGLAGPPPPPSQPRCAGPRATVTCGPASSPLPATVDREGTQLEPGLASRMAIHRTVLMCLGLPLFLLPGARAQEQAPPGCSPDLNPLYYNLCDRSEAWGIILEAVAGAGVVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPSFSTCASRRFLFGVLFAICFSCLVAHVLALHFLVRKNHGPRGWVIFLVALLLSLVEVIINTEWLIITLVRGAGTEGDALGNGSAGWVAVSPCAIANADFVMALIYVMLLLLCAFSGAWSALCGRFKRWRKHGVFILLTTTASIAIWVVWIVMYTYGNRQHNSPTWDDPTLAIALATNAWAFVLFYVIPEVSQVTRSSPEQSYQGDLYPTRGVGYETILKEQKGQSMFVENKAFSMDEPASAKRPVSPYSGYNGQLLTSMYQPTEMTLMHKAPSDGAYDVILPRATANSQVTGSANSTLRAEDIYAAQGRQEATLPKEGKNSQVFRNPYVWD", "length": 494 }, "evidence": [ { "id": "A0A8V1AL54", "url": "https://omabrowser.org/oma/group/A0A8V1AL54/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2LTN0-1", "protein_name": "G-protein coupled receptor family C group 5 member C", "gene_name": "Gprc5c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATHRALLMCLGLPLFFPGAGAQNHAPPGCRSDLDPIYYNLCDRSGAWGIVLEAVAGAGVITTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLVAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGGGQVGPPGNGSADGTVTSPCAIANMDFVMALIYVMLLLLGAFLGAWPTLCGRFKRWRKHGVFVLLTTAISIAIWVVWIVMYTYGNKQHHSPTWDDPTLAIALAANAWTFVLFYVIPEVSQVTKPSPEQSYQGDMYPTRGVGYETILKEQTGQSMFVENKAFSMDEPASAKRPVSPYSGYNGQLVTSVYQPTEMALMHKGPSEGAYDVILPRATANSQVMGSANSTLRAEDMYMIQSHQVATPPKDGKISQDQSPKNKTRW", "length": 441 }, "evidence": [ { "id": "A0A8V1AL54", "url": "https://omabrowser.org/oma/group/A0A8V1AL54/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3KRC4-1", "protein_name": "G protein-coupled receptor family C group 5 member C", "gene_name": "Gprc5c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATHKTLLMCLGLPLFFPGALAQNHAPPGCSPDLDPLYYNLCDRSGAWGIVLEAVAGAGIITTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLIAHTLSLNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGGGQVSTPGNGSADWTVTSPCAIANMDFVMALIYVMLLLLAAFLGAWPTLCGRFKRWRKHGVFVLLTTATSIAIWVVWIVMYTYGNKQHHSPTWDDPTLAIALAANAWTFVFFYVIPEVSQVTKPSPEQSYQGDMYPTRGVGYETILKEQTGQSMFVENKAFSMDEPASAKRPVSPYSGYNGQLLTSVYQPTEMALMHKGPSEGAYDVILPRATANSQVMGSANSTLRAEDMYMVQSHQVATPTKDGKISQDQSPKNKTRW", "length": 441 }, "evidence": [ { "id": "A0A8V1AL54", "url": "https://omabrowser.org/oma/group/A0A8V1AL54/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K3J9-1", "protein_name": "G protein-coupled receptor family C group 5 member C", "gene_name": "Gprc5c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATHRTLLMCLGLPLFFPGALAQNHAPPGCSPDLDPLYYNLCDRSGAWGIVSEAVAGAGIITTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLVAHVLSLNFLTRKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGGGQVSPLGNVSADSTMTSPCAIANMDFVMALIYVMLLLLTAFLGAWPTLCGRFKRWRKHGVFVLLTTVISIAIWVVWIVMYTYGNEQHHSPTWDDPTLAIALAANAWTFVLFYVIPEVSQVTKPSPEQSYQGDMYPTRGVGYETILKEQTGQSMFVENKAFSMDEPASAKRPVSPYSGYNGQLLTSVYQPTEMALMHKGPSEGAYDVILPRATANSQVMGSANSTLRAEDMYMVQSHQVATPPKDGKISQVFRNPYVWD", "length": 440 }, "evidence": [ { "id": "A0A8V1AL54", "url": "https://omabrowser.org/oma/group/A0A8V1AL54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ84-1", "protein_name": "G protein-coupled receptor family C group 5 member C", "gene_name": "GPRC5C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAIHKALVMCLGLPLFLFPGAWAQGHVPPGCSQGLNPLYYNLCDRSGAWGIVLEAVAGAGIVTTFVLTIILVASLPFVQDTKKRSLLGTQVFFLLGTLGLFCLVFACVVKPDFSTCASRRFLFGVLFAICFSCLAAHVFALNFLARKNHGPRGWVIFTVALLLTLVEVIINTEWLIITLVRGSGEGGPQGNSSAGWAVASPCAIANMDFVMALIYVMLLLLGAFLGAWPALCGRYKRWRKHGVFVLLTTATSVAIWVVWIVMYTYGNKQHNSPTWDDPTLAIALAANAWAFVLFYVIPEVSQVTKSSPEQSYQGDMYPTRGVGYETILKEQKGQSMFVENKAFSMDEPVAAKRPVSPYSGYNGQLLTSVYQPTEMALMHKVPSEGAYDIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPYVWD", "length": 441 }, "evidence": [ { "id": "A0A8V1AL54", "url": "https://omabrowser.org/oma/group/A0A8V1AL54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL54", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL54" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 368, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 13 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL56-1", "uniprot_ac": "A0A8V1AL56", "uniprot_id": "A0A8V1AL56_CHICK", "mass": { "chemical_mass": 81099.0, "monoisotopic_mass": 81099.0 }, "refseq": { "ac": "XP_003642469", "name": "nuclear pore complex protein Nup88", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642469" }, "gene_names": [ { "name": "NUP88", "type": "recommended", "evidence": [ { "id": "A0A8V1AL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ] }, { "name": "NUP88", "type": "synonym", "evidence": [ { "id": "XP_003642469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642469" } ] } ], "protein_names": [ { "name": "Nucleoporin 88", "type": "synonym", "evidence": [ { "id": "A0A8V1AL56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup88", "type": "synonym", "evidence": [ { "id": "XP_003642469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642469" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_003642469.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642469" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP88", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56", "locus": { "chromosome": "19", "start_pos": 3929972, "end_pos": 3921435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029253", "url": "https://www.ensembl.org/id/ENSGALG00010029253" } ] } } ], "crossref": [ { "id": "A0A8V1AL56", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL56", "database": "AlphaFoldDB", "categories": [] }, { "id": "417501", "url": "https://www.ncbi.nlm.nih.gov/gene/417501", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417501", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417501", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AYSCPIH", "url": "https://omabrowser.org/oma/group/AYSCPIH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL56", "url": "https://www.orthodb.org/?gene=A0A8V1AL56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13257:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13257:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855196", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855229", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642469", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEWGPAEQWRAALPQHAAFGRLRDSGPAPSAAPRSPLIRSLLLGLDGDLLLWDGERGALLDIDLRRLSGAEPELGRYQTLLCINPPLFEVYQTLLSPARRHVALIGTKGLSAVELPKRWGKNSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAWYPCETLEPHVVLLTSDNTIRIYSLKVPQAPIKVIALSDAEEETLIINRGRAYTASLGETAVAFDFGPLVPVPVSVLGQRGSEEVLAFPLYILYENGETFLTYINLLQSAGNLGKLLGPLPMHPAAEDNYGYDACAVLCLPCIPNILVIATESGVLYHCVVLDAEEDEEQSEKSWDPRSDLVPSLYVFECVELELALKLASGDEEEPLESDFSCPIKLHRDPKCPTRYHCTHEAGVHSVGLTWISKLQKFLGSDEEDKDGLQELGAEQKCFVEHILCTKPLPCRQPAPVRGFWIVSDVLGPTMICITNNYECITRPLLTAVHPASPSLLCTKEDKDDATSPLRVLAESQHSFEKHIQSILRRTSANPLLLKSADKEAAPPPEECLQLLSRATQVFREEYILKQDLAKEEIQQRVKLLWGQKKKQLEDLNYCREEKKSLREMAERLADKYEEAKEKQEDIMNRMKKVLRSFHSQLPVISDSERDMKKELQTIHDQLQHLSNAIRQVKMKKEYQQKKMEKGISPRKPSITLSAYQSKCIQTVLKEEGERIREMVKQINDIRGHVNF", "length": 722, "header": "tr|A0A8V1AL56-1|A0A8V1AL56_CHICK Isoform 1 of Nucleoporin 88 OS=Gallus gallus OX=9031 GN=NUP88 PE=1 SV=1 CANONICAL=A0A8V1AL56-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AL56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56/entry#A0A8V1AL56-1", "sequence": { "sequence": "MAAEWGPAEQWRAALPQHAAFGRLRDSGPAPSAAPRSPLIRSLLLGLDGDLLLWDGERGALLDIDLRRLSGAEPELGRYQTLLCINPPLFEVYQTLLSPARRHVALIGTKGLSAVELPKRWGKNSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAWYPCETLEPHVVLLTSDNTIRIYSLKVPQAPIKVIALSDAEEETLIINRGRAYTASLGETAVAFDFGPLVPVPVSVLGQRGSEEVLAFPLYILYENGETFLTYINLLQSAGNLGKLLGPLPMHPAAEDNYGYDACAVLCLPCIPNILVIATESGVLYHCVVLDAEEDEEQSEKSWDPRSDLVPSLYVFECVELELALKLASGDEEEPLESDFSCPIKLHRDPKCPTRYHCTHEAGVHSVGLTWISKLQKFLGSDEEDKDGLQELGAEQKCFVEHILCTKPLPCRQPAPVRGFWIVSDVLGPTMICITNNYECITRPLLTAVHPASPSLLCTKEDKDDATSPLRVLAESQHSFEKHIQSILRRTSANPLLLKSADKEAAPPPEECLQLLSRATQVFREEYILKQDLAKEEIQQRVKLLWGQKKKQLEDLNYCREEKKSLREMAERLADKYEEAKEKQEDIMNRMKKVLRSFHSQLPVISDSERDMKKELQTIHDQLQHLSNAIRQVKMKKEYQQKKMEKGISPRKPSITLSAYQSKCIQTVLKEEGERIREMVKQINDIRGHVNF", "length": 722, "header": "tr|A0A8V1AL56-1|A0A8V1AL56_CHICK Isoform 1 of Nucleoporin 88 OS=Gallus gallus OX=9031 GN=NUP88 PE=1 SV=1 CANONICAL=A0A8V1AL56-1" }, "locus": { "chromosome": "19", "start_pos": 3929805, "end_pos": 3921470, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070710.1", "url": "https://www.ensembl.org/id/ENSGALT00010070710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043401.1", "url": "https://www.ensembl.org/id/ENSGALP00010043401.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417501", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417501", "resource": "KEGG Pathway" }, { "id": "R-GGA-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-GGA-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-GGA-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-GGA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-GGA-1855170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "resource": "Reactome", "description": "IPs transport between nucleus and cytosol" }, { "id": "R-GGA-1855196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-GGA-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A9U8-1", "protein_name": "Nucleoporin 88", "gene_name": "NUP88", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVEGATGDGEVWQTWLPNHAVFLRLREGLKNQSPAEVEKPASSSLSSSPPLLTRNLVLGLGGELFLWDGEGSCFLVVRLRSLSGAGEEPSLSQYQRLLCINPPLFEIYQVLLSPTQQHVALIGIKGLMILELPKRWGKNSEFEGGKSTVNCSTTPIAERFFTSSTSLTLKHAAWYPSEMMDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLSAVPKNVFGQKGKDEVVAYPLYILRENGETFLMYVSLVHSPGSVGKLLGPLPMHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTSEKSWDSKADLIPSLYVFECVELELALKLASGEDDPFDSDFSCPIKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELATEQKCFVEHILCTKPLPCREPAPIRGFWIVPDILGPTMICITSNYECLTRPLLSTVHSASPPLLCTRDDVEVAESPLRILAETPDSFEKHIRSILQRSVANPAFLKSSEKDTAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKRKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHSQLPVLSDSERDMKKELQLIPDQLRHLGNAIRQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 739 }, "evidence": [ { "id": "A0A8V1AL56", "url": "https://omabrowser.org/oma/group/A0A8V1AL56/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2CEI4-1", "protein_name": "Nucleoporin 88", "gene_name": "nup88", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLAGDRWREALKNHDIFNNLQERLHLEPQGTSKRIAKNLTFCLNGDLFIWDSVESVFYTTNLRQLNSDGEPDTSRYQTLLCINPPLFEVCQVLVSPSQYHVALIGQRGATVLELPQRWGKKSEFEGGRIQINCKTIPVAERFFTSSASVTLRQAVWYPSETEEPHLVLLTSDNTIRFYNLKEPQSPARVLSVSQMDDDSSVHTRSRSYAASLGETAVAFDFGPLADSPHLSSLRMKAELVVYPLYILYGNGETFLNYISLSHSVGSLGKPMGPLPMYPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEAEEEEDGGAVERWSRGSETAPSLYVFECVELELTLKLPAGEEEEITESDFTCPIRLHRDPLCQHRYHCTHEAGVHSVGLTWFKKLHKFLESDEEDKDSLQELAAEQRCIVEHILCTRPLANSLPAPVRGFWIVSDLSLGATMICITSTYECLLLPLLSSIRPASPPLLCSHPGAGSDSSPLRGLAEDSFEQHIRNILARSSTNPLMLRSGDKDSSPPPSECLQLLSRATQVFREEYILKLGLAHEEMQRRVKLLSGQKNKQLEDLALCREDRKSLTEAAERLADKYEDAKYRQEAIMNRVKRVLGSLRSQLPVLSDSEKDMRKELQTINDQLRHLDNGIKQVNMKKDYQKKQMNAGASPAHSSLTLNAHQRKCLQGVLKEQGEHIAGMMKQIKDIKNHFSF", "length": 720 }, "evidence": [ { "id": "A0A8V1AL56", "url": "https://omabrowser.org/oma/group/A0A8V1AL56/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O08658-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "Nup88", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAGPVGDGELWQSWLPNHVVFLRLREGLKNQSPAEADKPATSTSPSCPPLPPHLPTRNLVFGLGGELFLWDAEGSAFLVVRLRGPSGGSVEPPLSQYQRLLCINPPLFEIHQVLLSPTQHHVALIGTKGLMALELPQRWGKDSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAWYPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLVTVSKNMFEQKDREAVAYPLYILYENGETFLTYVSLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEDDDQTLEKSWDPRADLIPSLYVFECVELELALKLASAEDDPFASDFSCPIKLHRDPKCPSRYHCSHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELTAEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTREDAGVAESPLRILAEAPDSFEKHIKRILQRSAANPALLKSSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKRKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHTQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 742 }, "evidence": [ { "id": "A0A8V1AL56", "url": "https://omabrowser.org/oma/group/A0A8V1AL56/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CEC0-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "Nup88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVGPLGDGELWQSWLPNHVVFLRLREGVRNQSPAEAEKPAASTSPSCPSLPPHLPTRNLVFGLGGELFLWDAEGSAFLVVRLRGPSGGGVEPPLSQYQRLLCINPPLFEIHQVLLSPTQHHVALIGSKGLMALELPQRWGKDSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAWYPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLVTVSKNIFEQKDRDVVAYPLYILYENGETFLTYVSLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEEDDQTLEKSWDPRADFIPSLYVFECVELELALKLASGEDDPFASDFSCPIKLHRDPKCPSRYHCSHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELTAEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTQEDAEVAESPLRILAETPDSFEKHIKRILQRSAANPAFLKNCSARSSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKRKQLEDLNYCREERVSHLFRKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHAQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVTF", "length": 753 }, "evidence": [ { "id": "A0A8V1AL56", "url": "https://omabrowser.org/oma/group/A0A8V1AL56/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNVVFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRSVANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF", "length": 741 }, "evidence": [ { "id": "A0A8V1AL56", "url": "https://omabrowser.org/oma/group/A0A8V1AL56/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9GYU8-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "mbo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLTDVLELNKTELFAKIRNGLPVVQRTQNLLDCKDDLLFAWHAKDSCLLVRNWRSSLAAKVNIQFQTLIPSSLVSLEVDRVLASNEGSLVALSGPRGVVIMELPRRWGPDGYYKDGKPVITCRTFGLDTQLFLKNPHLEVRQVRWHPHSVSDSTLLVLLNNNTIRVYNHSKLRHVWQVGPPVLRSGANNSLCDFGELAVDFDIAPAAKPRVTEPETAGNNETTLDKSNKTLVAAKSLPKQERIEWPMVVLRENGNIYILMTGVDSENTRLQGPVTITPQAHDNYGLESCALMIIPSLPPTIVIAESNGKLHHALLMEAEATEHSFNEVDDSVLIEPAEYVVHVLETVELELGISAPATGKEGGNCPIYLKRDLINELRYFAYHNAGLHAVTVSFIAELQRYLESESDEDRLELAVSASAEYILCTKFDSSETVNAVFGLALLQIPAGIVLLLGSGQVISLKLVIDAQLLVTPNENKPVDSEVSQQESGPPFVDTIKSLLQRSVNQPILADKLSSPSAQESFELLNQAIEVLREQYLKRHDLVRAAFTRHINQIQLKKEQQLQEIQDLEQERELISERAHKLAERFEEISYNQELLVRKCNALMQRANASLPNSVIAEREFSQEVIRLNKVTQSLAAGLETAKKTFNKQRYHIAQSQEDLKKNAYELPEKQHRTITEILTQLTGEIDRQITDVKRINKIVGI", "length": 702 }, "evidence": [ { "id": "A0A8V1AL56", "url": "https://omabrowser.org/oma/group/A0A8V1AL56/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ribosomal large subunit export from nucleus", "id": "GO:0000055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ], "pmid": "" }, { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ], "pmid": "" }, { "name": "ribosomal small subunit export from nucleus", "id": "GO:0000056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL58-1", "uniprot_ac": "A0A8V1AL58", "uniprot_id": "A0A8V1AL58_CHICK", "mass": { "chemical_mass": 125972.0, "monoisotopic_mass": 125972.0 }, "refseq": {}, "gene_names": [ { "name": "FBF1", "type": "recommended", "evidence": [ { "id": "A0A8V1AL58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ] } ], "protein_names": [ { "name": "Fas binding factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AL58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58", "locus": { "chromosome": "18", "start_pos": 5245065, "end_pos": 5231797, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010030109", "url": "https://www.ensembl.org/id/ENSGALG00010030109" } ] } } ], "crossref": [ { "id": "A0A8V1AL58", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL58", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR033561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL58", "url": "https://www.orthodb.org/?gene=A0A8V1AL58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMK6", "url": "https://www.orthodb.org/?gene=A0A8V1AMK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP36", "url": "https://www.orthodb.org/?gene=A0A8V1AP36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33689", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33689", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33689:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33689:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21007", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21007", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP36", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSSIDDVLDDLLGYDDEGPAKSSQPAGVSSGRARGSSLQASKKSFLEDDFFSKLPAEDMEAAEGSSISDADPQAVLQTLKEMDDMEADLLGMSKPSSGLGKAATKGPGKFSTSEGAVKTSGKMPAPEKGESAPEMDKKPLSSPPTSRQYRKFNFEDVDDPLAGLLSEEEQDAPRKPSPKGSERRPERKTELGKEKDPLPPQTPLHTTAPARRREELTFEDDDDDLMDVLGFGDGQKGDQKHGKKAEDREEVRPARSKLDELLGRGSVAKILERPGAGEHREFKLDKKYQKQPEKEEGWDEEDFVFGAYQPTVATTPEGRPSRRQSVSRFSAENSSEPKPDPHSKPPPAASQSPARGSRAGGDWLGLKDEDFLDSEPPSPAKTSPVVSSQQLLAKEQATSKPNQLEEDNWLSAALSRKKAQAQVKAQERSAVPLETTGKGLDPSPAVSQPATSTGAAAQAAALQDKAASADSSGHPVPWLGTVTQTSAHPPEPAKRDPLRDVSPSDPAASSPAEQGMQGPAPLAQVTMPSTPLQAASQLQAESPPLGSVHERRPGAPTAQPYEDATSYRAALLSAQARVAELESQVRMLELERTQHKLLLESLQQRHQEDLDLLESAHRSRVKVVEETYGQREERLRREKEQLEAQLLSQSQDAERARADLVAQHKQRVATLEQQSAQELERLRELQRSSVQEMLKDHEEQLQRLKRLKDQEIDAVTSATSHTRSLNGVIEQMERFSSDLHSLSHKVEATHHTTSQELAMGARQRDEQLKVLQDRLSQQQRDMEEERSRLQEVIAKMEARLSEQTRLLEQERWRVTAEQSKVESLQRSLEEQRRLMTQQLSMERAELERAKSALLEEQKSVMQKCSEERRKLAVEWAEFHTQQQLSKERMERDIDRALQLDSQREGTIMSLAKEQAELKVRSRELKVKEEQLARDRLLLDEAWHELRLEKEKVKGATLRIRQQEEEIKNMSKLSAQKYEEGERALQDACRIESEHQARLQVMQQHLEQLKQQEQHLQQERLSMAHQRRQLEQLHKKLPNNPTLLLTTDQDLSASTKGLSSTLSFPPPIRTLPGHRSVGTTASMELYAKLLVLKHRAQQDRSFLEDEQLFLETLKKASCNTSPLSV", "length": 1125, "header": "tr|A0A8V1AL58-1|A0A8V1AL58_CHICK Isoform 1 of Fas binding factor 1 OS=Gallus gallus OX=9031 GN=FBF1 PE=4 SV=1 CANONICAL=A0A8V1AL58-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AL58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58/entry#A0A8V1AL58-1", "sequence": { "sequence": "MVSSIDDVLDDLLGYDDEGPAKSSQPAGVSSGRARGSSLQASKKSFLEDDFFSKLPAEDMEAAEGSSISDADPQAVLQTLKEMDDMEADLLGMSKPSSGLGKAATKGPGKFSTSEGAVKTSGKMPAPEKGESAPEMDKKPLSSPPTSRQYRKFNFEDVDDPLAGLLSEEEQDAPRKPSPKGSERRPERKTELGKEKDPLPPQTPLHTTAPARRREELTFEDDDDDLMDVLGFGDGQKGDQKHGKKAEDREEVRPARSKLDELLGRGSVAKILERPGAGEHREFKLDKKYQKQPEKEEGWDEEDFVFGAYQPTVATTPEGRPSRRQSVSRFSAENSSEPKPDPHSKPPPAASQSPARGSRAGGDWLGLKDEDFLDSEPPSPAKTSPVVSSQQLLAKEQATSKPNQLEEDNWLSAALSRKKAQAQVKAQERSAVPLETTGKGLDPSPAVSQPATSTGAAAQAAALQDKAASADSSGHPVPWLGTVTQTSAHPPEPAKRDPLRDVSPSDPAASSPAEQGMQGPAPLAQVTMPSTPLQAASQLQAESPPLGSVHERRPGAPTAQPYEDATSYRAALLSAQARVAELESQVRMLELERTQHKLLLESLQQRHQEDLDLLESAHRSRVKVVEETYGQREERLRREKEQLEAQLLSQSQDAERARADLVAQHKQRVATLEQQSAQELERLRELQRSSVQEMLKDHEEQLQRLKRLKDQEIDAVTSATSHTRSLNGVIEQMERFSSDLHSLSHKVEATHHTTSQELAMGARQRDEQLKVLQDRLSQQQRDMEEERSRLQEVIAKMEARLSEQTRLLEQERWRVTAEQSKVESLQRSLEEQRRLMTQQLSMERAELERAKSALLEEQKSVMQKCSEERRKLAVEWAEFHTQQQLSKERMERDIDRALQLDSQREGTIMSLAKEQAELKVRSRELKVKEEQLARDRLLLDEAWHELRLEKEKVKGATLRIRQQEEEIKNMSKLSAQKYEEGERALQDACRIESEHQARLQVMQQHLEQLKQQEQHLQQERLSMAHQRRQLEQLHKKLPNNPTLLLTTDQDLSASTKGLSSTLSFPPPIRTLPGHRSVGTTASMELYAKLLVLKHRAQQDRSFLEDEQLFLETLKKASCNTSPLSV", "length": 1125, "header": "tr|A0A8V1AL58-1|A0A8V1AL58_CHICK Isoform 1 of Fas binding factor 1 OS=Gallus gallus OX=9031 GN=FBF1 PE=4 SV=1 CANONICAL=A0A8V1AL58-1" }, "locus": { "chromosome": "18", "start_pos": 5244950, "end_pos": 5231913, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072688.1", "url": "https://www.ensembl.org/id/ENSGALT00010072688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044875.1", "url": "https://www.ensembl.org/id/ENSGALP00010044875.1" } ] } }, { "isoform_ac": "A0A8V1AMK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58/entry#A0A8V1AMK6-1", "sequence": { "sequence": "MATKSKSSVRGSIDDVLDDLLGYDDEGPAKSSQPAGVSSGRARGSSLQASKKSFLEDDFFSKLPAEDMEAAEGSSISDADPQAVLQTLKEMDDMEADLLGMSKPSSGLGKAATKGPGKFSTSEGAVKTSGKMPAPEKGESAPEMDKKPLSSPPTSRQYRKFNFEDVDDPLAGLLSEEEQDAPRKPSPKGSERRPERKTELGKEKDPLPPQTPLHTTAPARRREELTFEDDDDDLMDVLGFGDGQKGDQKHGKKAEDREEVRPARSKLDELLGRGSVAKILERPGAGEHREFKLDKKYQKQPEKEEGWDEEDFVFGAYQPTVATTPEGRPSRRQSVSRFSAENSSEPKPDPHSKPPPAASQSPARGSRAGGDWLGLKDEDFLDSEPPSPAKTSPVVSSQQLLAKEQATSKPNQLEEDNWLSAALSRKKAQAQVKAQERSAVPLETTGKGLDPSPAVSQPATSTGAAAQAAALQDKAASADSSGHPVPWLGTVTQTSAHPPEPAKRDPLRDVSPSDPAASSPAEQGMQGPAPLAQVTMPSTPLQAASQLQAESPPLGSVHERRPGAPTAQPYEDATSYRAALLSAQARVAELESQVRMLELERTQHKLLLESLQQRHQEDLDLLESAHRSRVKVVEETYGQREERLRREKEQLEAQLLSQSQDAERARADLVAQHKQRVATLEQQSAQELERLRELQRSSVQEMLKDHEEQLQRLKRLKDQEIDAVTSATSHTRSLNGVIEQMERFSSDLHSLSHKVEATHHTTSQELAMGARQRDEQLKVLQDRLSQQQRDMEEERSRLQEVIAKMEARLSEQTRLLEQERWRVTAEQSKVESLQRSLEEQRRLMTQQLSMERAELERAKEQAELKVRSRELKVKEEQLARDRLLLDEAWHELRLEKEKVKGATLRIRQQEEEIKNMSKLSAQKYEEGERALQDACRIESEHQARLQVMQQHLEQLKQQEQHLQQERLSMAHQRRQLEQLHKKLPNNPTLLLTTDQDLSASTKGLSSTLSFPPPIRTLPGHRSVGTTASMELYAKLLVLKHRAQQDRSFLEDEQLFLETLKKASCNTSPLSV", "length": 1071, "header": "tr|A0A8V1AMK6-1|A0A8V1AMK6_CHICK Computationally mapped isoform of Fas binding factor 1 OS=Gallus gallus OX=9031 GN=FBF1 PE=4 SV=1 CANONICAL=A0A8V1AL58-1" }, "locus": { "chromosome": "18", "start_pos": 5244950, "end_pos": 5231913, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072690.1", "url": "https://www.ensembl.org/id/ENSGALT00010072690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044877.1", "url": "https://www.ensembl.org/id/ENSGALP00010044877.1" } ] } }, { "isoform_ac": "A0A8V1AP36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58/entry#A0A8V1AP36-1", "sequence": { "sequence": "MATKSKSSVRGSIDDVLDDLLGYDDEGPAKSSQPAGVSSGRARGSSLQASKKSFLEDDFFSKLPAEDMEAAEGSSISDADPQAVLQTLKEMDDMEADLLGMSKPSSGLGKAATKGPGKFSTSEGAVKTSGKMPAPEKDVDDPLAGLLSEEEQDAPRKPSPKGSERRPERKTELGKEKDPLPPQTPLHTTAPARRREELTFEDDDDDLMDVLGFGDGQKGDQKHGKKAEDREEVRPARSKLDELLGRGSVAKILERPGAGEHREFKLDKKYQKQPEKEEGWDEEDFVFGAYQPTVATTPEGRPSRRQSVSRFSAENSSEPKPDPHSKPPPAASQSPARGSRAGGDWLGLKDEDFLDSEPPSPAKTSPVVSSQQLLAKEQATSKPNQLEEDNWLSAALSRKKAQAQVKAQERSAVPLETTGKGLDPSPAVSQPATSTGAAAQAAALQDKAASADSSGHPVPWLGTVTQTSAHPPEPAKRDPLRDVSPSDPAASSPAEQGMQGPAPLAQVTMPSTPLQAASQLQAESPPLGSVHERRPGAPTAQPYEDATSYRAALLSAQARVAELESQVRMLELERTQHKLLLESLQQRHQEDLDLLESAHRSRVKVVEETYGQREERLRREKEQLEAQLLSQSQDAERARADLVAQHKQRVATLEQQSAQELERLRELQRSSVQEMLKDHEEQLQRLKRLKDQEIDAVTSATSHTRSLNGVIEQMERFSSDLHSLSHKVEATHHTTSQELAMGARQRDEQLKVLQDRLSQQQRDMEEERSRLQEVIAKMEARLSEQTRLLEQERWRVTAEQSKVESLQRSLEEQRRLMTQQLSMERAELERAKSALLEEQKSVMQKCSEERRKLAVEWAEFHTQQQLSKERMERDIDRALQLDSQREGTIMSLAKEQAELKVRSRELKVKEEQLARDRLLLDEAWHELRLEKEKVKGATLRIRQQEEEIKNMSKLSAQKYEEGERALQDACRIESEHQARLQVMQQHLEQLKQQEQHLQQERLSMAHQRRQLEQLHKKLPNNPTLLLTTDQDLSASTKGLSSTLSFPPPIRTLPGHRSVGTTASMELYAKLLVLKHRAQQDRSFLEDEQLFLETLKKASCNTSPLSV", "length": 1106, "header": "tr|A0A8V1AP36-1|A0A8V1AP36_CHICK Computationally mapped isoform of Fas binding factor 1 OS=Gallus gallus OX=9031 GN=FBF1 PE=4 SV=1 CANONICAL=A0A8V1AL58-1" }, "locus": { "chromosome": "18", "start_pos": 5244950, "end_pos": 5231913, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072689.1", "url": "https://www.ensembl.org/id/ENSGALT00010072689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044876.1", "url": "https://www.ensembl.org/id/ENSGALP00010044876.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "apical junction assembly", "id": "GO:0043297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "establishment of epithelial cell polarity", "id": "GO:0090162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "ciliary transition fiber", "id": "GO:0097539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1119, "end_pos": 1121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 969, "end_pos": 971, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL58" }, { "id": "PF21007", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fas-binding factor 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 589, "end_pos": 1115, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1119, "end_pos": 1121 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 969, "end_pos": 971 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL60-1", "uniprot_ac": "A0A8V1AL60", "uniprot_id": "A0A8V1AL60_CHICK", "mass": { "chemical_mass": 44735.0, "monoisotopic_mass": 44735.0 }, "refseq": { "ac": "XP_040506552", "name": "caspase-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506552" }, "gene_names": [ { "name": "CASP1", "type": "recommended", "evidence": [ { "id": "A0A8V1AL60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ] }, { "name": "CASP1", "type": "synonym", "evidence": [ { "id": "XP_040506552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506552" } ] } ], "protein_names": [ { "name": "Caspase 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AL60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60/entry#names_and_taxonomy" } ] }, { "name": "caspase-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040506552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506552" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506552" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CASP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60", "locus": {} } ], "crossref": [ { "id": "A0A8V1AL60", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL60", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001049", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001049", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00032", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00032", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08325", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08325", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395764", "url": "https://www.ncbi.nlm.nih.gov/gene/395764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ACRGANH", "url": "https://omabrowser.org/oma/group/ACRGANH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P7C1", "url": "https://www.orthodb.org/?gene=A0A1D5P7C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL60", "url": "https://www.orthodb.org/?gene=A0A8V1AL60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMX9", "url": "https://www.orthodb.org/?gene=A0A8V1AMX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APF7", "url": "https://www.orthodb.org/?gene=A0A8V1APF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47901", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47901", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47901:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47901:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00656", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00656", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-448706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-448706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620971", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620971", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9968551", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9968551", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040506552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P7C1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P7C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADQELLRVRADFVSRVRKAVVSNLLDELLAHRVLNQAEVDEVQEGNPVTTDKARSLIDTVRLKGPRASAIFIDSLRKHDCNLAEQLRLCAHAEPPGAPLAVPSTVGFSDPPVSSQDLQWIQQCPLSEYQRIKEAEGDQIYDIYQPRERRTRRALLICNTKFKHLRQRDGAEVDVKEMTKLLEGLGYNVECHEDKTSQEMTTVMKKFADHKDHLTSDSTFLVFMSHGMSTGICGTKSNGTTDILSFNTIYENFNNKHCRALMGKPKVVIIQCCRGDNIGSVQIRDSIDPEMPTSTSDGWRCVELQGSKTREAHLESDFATLYSSTPDTVSWRSPTEGSVFIQRLVEQFRNHAFNSDLQEMFRKVQRSFENFPRQLPTQERTTMLKKFYLFPGL", "length": 393, "header": "tr|A0A8V1AL60-1|A0A8V1AL60_CHICK Isoform 1 of Caspase 1 OS=Gallus gallus OX=9031 GN=CASP1 PE=1 SV=1 CANONICAL=A0A8V1AL60-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60/entry#A0A1D5P7C1-1", "sequence": { "sequence": "MQIYDIYQPRERRTRRALLICNTKFKHLRQRDGAEVDVKEMTKLLEGLGYNVECHEDKTSQEMTTVMKKFADHKDHLTSDSTFLVFMSHGMSTGICGTKSNGTTDILSFNTIYENFNNKHCRALMGKPKVVIIQCCRGDNIGSVQIRDSIDPEMPTSTSDGWRCVELQGSKTREAHLESDFATLYSSTPDTVSWRSPTEGSVFIQRLVEQFRNHAFNSDLQEMFRKVQRSFENFPRQLPTQERTTMLKKFYLFPGL", "length": 256, "header": "tr|A0A1D5P7C1-1|A0A1D5P7C1_CHICK Computationally mapped isoform of Caspase 1 OS=Gallus gallus OX=9031 GN=CASP1 PE=1 SV=1 CANONICAL=A0A8V1AL60-1" }, "locus": { "chromosome": "19", "start_pos": 1186222, "end_pos": 1183570, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071576.1", "url": "https://www.ensembl.org/id/ENSGALT00010071576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044266.1", "url": "https://www.ensembl.org/id/ENSGALP00010044266.1" } ] } }, { "isoform_ac": "A0A8V1AL60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60/entry#A0A8V1AL60-1", "sequence": { "sequence": "MADQELLRVRADFVSRVRKAVVSNLLDELLAHRVLNQAEVDEVQEGNPVTTDKARSLIDTVRLKGPRASAIFIDSLRKHDCNLAEQLRLCAHAEPPGAPLAVPSTVGFSDPPVSSQDLQWIQQCPLSEYQRIKEAEGDQIYDIYQPRERRTRRALLICNTKFKHLRQRDGAEVDVKEMTKLLEGLGYNVECHEDKTSQEMTTVMKKFADHKDHLTSDSTFLVFMSHGMSTGICGTKSNGTTDILSFNTIYENFNNKHCRALMGKPKVVIIQCCRGDNIGSVQIRDSIDPEMPTSTSDGWRCVELQGSKTREAHLESDFATLYSSTPDTVSWRSPTEGSVFIQRLVEQFRNHAFNSDLQEMFRKVQRSFENFPRQLPTQERTTMLKKFYLFPGL", "length": 393, "header": "tr|A0A8V1AL60-1|A0A8V1AL60_CHICK Isoform 1 of Caspase 1 OS=Gallus gallus OX=9031 GN=CASP1 PE=1 SV=1 CANONICAL=A0A8V1AL60-1" }, "locus": { "chromosome": "19", "start_pos": 1186222, "end_pos": 1182985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071575.1", "url": "https://www.ensembl.org/id/ENSGALT00010071575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044265.1", "url": "https://www.ensembl.org/id/ENSGALP00010044265.1" } ] } }, { "isoform_ac": "A0A8V1AMX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60/entry#A0A8V1AMX9-1", "sequence": { "sequence": "MFPGSGAVSSTTVWHCASSPGSATTPGARWAAPQGVVMGAVIVQGCSSVGTPCCAGAGRTLIGGDKRQRRKQEANFVSFLSSHKKWLLEPFGGPGAEGQWQIYDIYQPRERRTRRALLICNTKFKHLRQRDGAEVDVKEMTKLLEGLGYNVECHEDKTSQEMTTVMKKFADHKDHLTSDSTFLVFMSHGMSTGICGTKSNGTTDILSFNTIYENFNNKHCRALMGKPKVVIIQCCRGDNIGSVQIRDSIDPEMPTSTSDGWRCVELQGSKTREAHLESDFATLYSSTPDTVSWRSPTEGSVFIQRLVEQFRNHAFNSDLQEMFRKVQRSFENFPRQLPTQERTTMLKKFYLFPGL", "length": 355, "header": "tr|A0A8V1AMX9-1|A0A8V1AMX9_CHICK Computationally mapped isoform of Caspase 1 OS=Gallus gallus OX=9031 GN=CASP1 PE=1 SV=1 CANONICAL=A0A8V1AL60-1" }, "locus": { "chromosome": "19", "start_pos": 1186222, "end_pos": 1182689, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071574.1", "url": "https://www.ensembl.org/id/ENSGALT00010071574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044264.1", "url": "https://www.ensembl.org/id/ENSGALP00010044264.1" } ] } }, { "isoform_ac": "A0A8V1APF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60/entry#A0A8V1APF7-1", "sequence": { "sequence": "MSPGQMRMLLPTGTQRGQAKLACSRVLNQAEVDEVQEGNPVTTDKARSLIDTVRLKGPRASAIFIDSLRKHDCNLAEQLRLCAHAEPPGAPLAVPSTVGFSDPPVSSQDLQWIQQCPLSEYQRIKEAEGDQIYDIYQPRERRTRRALLICNTKFKHLRQRDGAEVDVKEMTKLLEGLGYNVECHEDKTSQEMTTVMKKFADHKDHLTSDSTFLVFMSHGMSTGICGTKSNGTTDILSFNTIYENFNNKHCRALMGKPKVVIIQCCRGDNIGSVQIRDSIDPEMPTSTSDGWRCVELQGSKTREAHLESDFATLYSSTPDTVSWRSPTEGSVFIQRLVEQFRNHAFNSDLQEMFRKVQRSFENFPRQLPTQERTTMLKKFYLFPGL", "length": 385, "header": "tr|A0A8V1APF7-1|A0A8V1APF7_CHICK Computationally mapped isoform of Caspase 1 OS=Gallus gallus OX=9031 GN=CASP1 PE=1 SV=1 CANONICAL=A0A8V1AL60-1" }, "locus": { "chromosome": "19", "start_pos": 1186222, "end_pos": 1182460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071577.1", "url": "https://www.ensembl.org/id/ENSGALT00010071577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044267.1", "url": "https://www.ensembl.org/id/ENSGALP00010044267.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-448706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-448706", "resource": "Reactome", "description": "Interleukin-1 processing" }, { "id": "R-GGA-5620971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620971", "resource": "Reactome", "description": "Pyroptosis" }, { "id": "R-GGA-9968551", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9968551", "resource": "Reactome", "description": "Regulation of GBP-mediated host defense" } ], "orthologs": [ { "uniprot_canonical_ac": "O75601-1", "protein_name": "Caspase-13", "gene_name": "CASP13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEDKHNKNPLKMLESLGKELISGLLDDFVEKNVLKLEEEEKKKIYDAKLQDKARVLVDSIRQKNQEAGQVFVQTFLNIDKNSTSIKAPEETVAGPDESVGSAATLKLCPHEEFLKLCKERAGEIYPIKERKDRTRLALIICNTEFDHMPPRNGAALDILGMKQLLEGLGYTVEVEEKLTARDMESVLWKFAAREEHKSSDSTFLVFMSHGILDGICGTMHSEEEPDVLPYDTIFRTFNNRNCLSLKDKPKVIIVQACRGANRGELWVSDSPPALADSFSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDIKKGSLFITRLITCFQKYAWCCHLEEVFRKVQQSFEKPNVKAQMPTVERLSMTRYFYLFPGN", "length": 377 }, "evidence": [ { "id": "A0A8V1AL60", "url": "https://omabrowser.org/oma/group/A0A8V1AL60/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P49662-1", "protein_name": "Caspase-4", "gene_name": "CASP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN", "length": 377 }, "evidence": [ { "id": "A0A8V1AL60", "url": "https://omabrowser.org/oma/group/A0A8V1AL60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5E9C1-1", "protein_name": "Caspase-4", "gene_name": "CASP4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEDKHNKNPLKMLESLGKELISGLLDDFVEKNVLKLEEEEKKKIYDAKLQDKARVLVDSIRQKNQEAGQVFVQTFLNIDKNSTSIKAPEETVAGPDESVGSAATLKLCPHEEFLKLCKERAGEIYPIKERKDRTRLALIICNTEFDHMPPRNGAALDILGMKQLLEGLGYTVEVEEKLTARDMESVLWKFAAREEHKSSDSTFLVFMSHGILDGICGTMHSEEEPDVLPYDTIFRTFNNRNCLSLKDKPKVIIVQACRGANRGELWVSDSPPALADSFSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDIKKGSLFITRLITCFQKYAWCCHLEEVFRKVQQSFEKPNVKAQMPTVERLSMTRYFYLFPGN", "length": 377 }, "evidence": [ { "id": "A0A8V1AL60", "url": "https://omabrowser.org/oma/group/A0A8V1AL60/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "AIM2 inflammasome complex", "id": "GO:0097169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" }, { "name": "NLRP3 inflammasome complex", "id": "GO:0072559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" }, { "name": "IPAF inflammasome complex", "id": "GO:0072557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072557", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" }, { "id": "PS50209", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50209" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARD", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 91, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AL60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" }, { "id": "PS50207", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p10", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 391, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AL60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL60" }, { "id": "PS50208", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50208" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Caspase family p20", "eco_id": "ECO_0000259", "start_pos": 150, "end_pos": 277, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 238, "end_pos": 240 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL80-1", "uniprot_ac": "A0A8V1AL80", "uniprot_id": "A0A8V1AL80_CHICK", "mass": { "chemical_mass": 46853.0, "monoisotopic_mass": 46853.0 }, "refseq": { "ac": "XP_003643443", "name": "protein ABHD8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643443" }, "gene_names": [ { "name": "ABHD8", "type": "recommended", "evidence": [ { "id": "A0A8V1AL80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ] }, { "name": "ABHD8", "type": "synonym", "evidence": [ { "id": "XP_003643443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643443" } ] } ], "protein_names": [ { "name": "Protein ABHD8", "type": "recommended", "evidence": [ { "id": "A0A8V1AL80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80/entry#names_and_taxonomy" } ] }, { "name": "Alpha/beta hydrolase domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "A0A8V1AL80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80/entry#names_and_taxonomy" } ] }, { "name": "protein ABHD8", "type": "synonym", "evidence": [ { "id": "XP_003643443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643443" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052559.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003643443.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643443" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABHD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80", "locus": { "chromosome": "28", "start_pos": 3837193, "end_pos": 3844843, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028588", "url": "https://www.ensembl.org/id/ENSGALG00010028588" } ] } } ], "crossref": [ { "id": "A0A8V1AL80", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL80", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857580", "url": "https://www.ncbi.nlm.nih.gov/gene/100857580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857580", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VHCQRRI", "url": "https://omabrowser.org/oma/group/VHCQRRI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL80", "url": "https://www.orthodb.org/?gene=A0A8V1AL80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42886", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42886", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42886:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42886:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNSITEGFLCCLMGKTTNAVGPLDSVESSNGYSFLEVKPGRILRVRHSAPSRPPAEPAEEPGAAERGTVHCKRKITLYRNGQLVIENLGDAVRSEILHCSNSTAEPSSTVELELSELAGQAPAQGSAGTPGCSTPGCGARDAAGGKRRKRKPKKVINIDCKKQITSCKGTHGDVVLFFIHGVGGSLDIWKEQLDFFTKLGYEVVAPDLAGHGCSSAPQIAAAYTFYALAEDMRAVFKRYAKKRNILIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELAVPVLLVHGMHDKFVPVEEDQRMAEILLIAFLKVIDEGSHMVMMECPETVNTLLHEFVLWEPETPAGDGQGEKK", "length": 431, "header": "tr|A0A8V1AL80-1|A0A8V1AL80_CHICK Isoform 1 of Protein ABHD8 OS=Gallus gallus OX=9031 GN=ABHD8 PE=3 SV=1 CANONICAL=A0A8V1AL80-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AL80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80/entry#A0A8V1AL80-1", "sequence": { "sequence": "MLNSITEGFLCCLMGKTTNAVGPLDSVESSNGYSFLEVKPGRILRVRHSAPSRPPAEPAEEPGAAERGTVHCKRKITLYRNGQLVIENLGDAVRSEILHCSNSTAEPSSTVELELSELAGQAPAQGSAGTPGCSTPGCGARDAAGGKRRKRKPKKVINIDCKKQITSCKGTHGDVVLFFIHGVGGSLDIWKEQLDFFTKLGYEVVAPDLAGHGCSSAPQIAAAYTFYALAEDMRAVFKRYAKKRNILIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELAVPVLLVHGMHDKFVPVEEDQRMAEILLIAFLKVIDEGSHMVMMECPETVNTLLHEFVLWEPETPAGDGQGEKK", "length": 431, "header": "tr|A0A8V1AL80-1|A0A8V1AL80_CHICK Isoform 1 of Protein ABHD8 OS=Gallus gallus OX=9031 GN=ABHD8 PE=3 SV=1 CANONICAL=A0A8V1AL80-1" }, "locus": { "chromosome": "28", "start_pos": 3840205, "end_pos": 3838316, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069231.1", "url": "https://www.ensembl.org/id/ENSGALT00010069231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042673.1", "url": "https://www.ensembl.org/id/ENSGALP00010042673.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 130, "start_aa": "Thr", "end_pos": 130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr130", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 280, "start_aa": "Thr", "end_pos": 280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100857580", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857580", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BM17-1", "protein_name": "Protein ABHD8", "gene_name": "ABHD8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTGVTDGIFCCLLGAPPNAVGPLESVESSDGYTFVEVKPGRVLRVKHAGPAPAPTPSPPLSDTAQGDQTGLVRCQRRITVYRNGRLLVENLGRAPRADLLHGQNGSGEPPAALEVELADPAGSDGRSGTGSAGSGSGGRRRRARRPKRTIHIDCEKRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSFCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPETVNTLLHEFLLWEPEPSPKALPEPLPAPLEEKK", "length": 432 }, "evidence": [ { "id": "A0A8V1AL80", "url": "https://omabrowser.org/oma/group/A0A8V1AL80/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AIY3-1", "protein_name": "Protein ABHD8", "gene_name": "Abhd8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSLKLDSVLTREGQRTGKGKGHTMLTGVTDGFFCCLLGTPPNAVRPLESVESSDGYTFVEVKPGRVLRVKHACPAPIPSPPPPPPEDNPGVKTGLVRCQRRITVYRNGRLVVENLGRAPRADLQGRSGSGDPPGSLEVELAEPAGGDTRATPGSGRRRRPRRPKRTIHIDCEQRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFTRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIEEGSHMVMLECPETVNTLLHEFLLWEPEPEAEPKLEPKSKPQPLQLQSDPAPGEEK", "length": 459 }, "evidence": [ { "id": "A0A8V1AL80", "url": "https://omabrowser.org/oma/group/A0A8V1AL80/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q17QP1-1", "protein_name": "Protein ABHD8", "gene_name": "ABHD8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLTGVTDGIFCCLLGAPPNAVGPLESVESSDGYTFVEVKPGRVLRVKHAGPAPAPTPPPPLSDAAQGDQSGLVRCQRRITVYRNGRLLVENLGRAPRADLLHGQNGSGEPPAALEVELADPAGSDGRSVPGSAGSGSGGRRRRARRPKRTIHIDCEKRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSVFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPETVNTLLHEFLLWEPEPSPKALPEPLPAPPEEKK", "length": 432 }, "evidence": [ { "id": "A0A8V1AL80", "url": "https://omabrowser.org/oma/group/A0A8V1AL80/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R0P8-1", "protein_name": "Protein ABHD8", "gene_name": "Abhd8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSEHTMLTGVTDGFFCCLLGTPPNAVRPLESVESSDGYTFVEVKPGRVLRVKHAGPAPIPTPPPPPPEDDPGVKTGLVRCQRRITVYRNGRLVVENLGRAPRADLQGRSGSGDPPAALEVELAEPAGGDTRANPGSGRRRRPRRPKRTIHIDCEQRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFTRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIEEGSHMVMLECPETVNTLLHEFLLWEPEPEAEPKLEPKPKPQLLQPEPAPGEEK", "length": 439 }, "evidence": [ { "id": "A0A8V1AL80", "url": "https://omabrowser.org/oma/group/A0A8V1AL80/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96I13-1", "protein_name": "Protein ABHD8", "gene_name": "ABHD8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTGVTDGIFCCLLGTPPNAVGPLESVESSDGYTFVEVKPGRVLRVKHAGPAPAAAPPPPSSASSDAAQGDLSGLVRCQRRITVYRNGRLLVENLGRAPRADLLHGQNGSGEPPAALEVELADPAGSDGRLAPGSAGSGSGSGSGGRRRRARRPKRTIHIDCEKRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSFCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPETVNTLLHEFLLWEPEPSPKALPEPLPAPPEDKK", "length": 439 }, "evidence": [ { "id": "A0A8V1AL80", "url": "https://omabrowser.org/oma/group/A0A8V1AL80/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phosphatidic acid biosynthetic process", "id": "GO:0006654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "pmid": "" }, { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "pmid": "" }, { "name": "negative regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lysophosphatidic acid acyltransferase activity", "id": "GO:0042171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "pmid": "" }, { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "pmid": "" }, { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL80", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL80" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 278, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 130, 135, 280 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL85-1", "uniprot_ac": "A0A8V1AL85", "uniprot_id": "A0A8V1AL85_CHICK", "mass": { "chemical_mass": 70870.0, "monoisotopic_mass": 70870.0 }, "refseq": {}, "gene_names": [ { "name": "SRRM3", "type": "recommended", "evidence": [ { "id": "A0A8V1AL85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" } ] } ], "protein_names": [ { "name": "Serine/arginine repetitive matrix 3", "type": "synonym", "evidence": [ { "id": "A0A8V1AL85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRRM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85", "locus": { "chromosome": "19", "start_pos": 4745043, "end_pos": 4764927, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029613", "url": "https://www.ensembl.org/id/ENSGALG00010029613" } ] } } ], "crossref": [ { "id": "A0A8V1AL85", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL85", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21376", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21376", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417516", "url": "https://www.ncbi.nlm.nih.gov/gene/417516", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KCTEFEM", "url": "https://omabrowser.org/oma/group/KCTEFEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AE49", "url": "https://www.orthodb.org/?gene=A0A8V1AE49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL85", "url": "https://www.orthodb.org/?gene=A0A8V1AL85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34755", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34755", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34755:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34755:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AE49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AE49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALYNNGANVPSPQEASNGFSQPGASGTWHKAEEEVRLVEPSLVKKAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDQHGRQIVIENHHGLDGEEYTAQYPEYGEGCLLQCDCSAECYRDDSSHREYRLKRRSSSSTSPPPKKKKKKKSGHRRNRKKRKPGSERSCDSSSPIRKEKKKKTGKKHRRDRSESGSRKKRRHRSRSPKNKRKEKNKERKRSRSASPAWRSHRRSSCSSHSASLSSDYSNSKSPSRLSPKHREDGPKGNSARSSRSPSSSSPRRSASPHQNGHKGSAQNGRHSHGPALEEPTDKRPASPSPSPRPRGRTDPPSPRTRGGRHGARSPSLERAKHGHRHRSRSASPPRHRGQAPRLPAPAGLSPTGYSSDSEGSVCSHPLSPDRTHGAHAKKVKERHHRGRPNSSSESSAKHSRHGASERRKSPSHSTGHRSTSWSSSGSLSKSRSRSRDKRAARSRSRSPSQKKTASREKDNEPRTRHSDPDPARARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSLSTYSYSRSRSRSYDTYSTSRSRSRTRSPPSRSRSPPSRSPSYNSRSSSESAGF", "length": 627, "header": "tr|A0A8V1AL85-1|A0A8V1AL85_CHICK Isoform 1 of Serine/arginine repetitive matrix 3 OS=Gallus gallus OX=9031 GN=SRRM3 PE=4 SV=1 CANONICAL=A0A8V1AL85-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AE49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85/entry#A0A8V1AE49-1", "sequence": { "sequence": "MALYNNGANVPSPQEASNGFSQPGASGTWHKAEEEVRLVEPSLVKKAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDQHGRQIVIENHHGLDGEEYTAQYPEYGEGCLLQCDCSAECYRDDSSHREYRLKRRSSSSTSPPPKKKKKKKSGHRRNRKKRKPGSERSCDSSSPIRKEKKKKTGKKHRRDRSESGSRKKRRHRSRSPKNKRKEKNKERKRSRSASPAWRSHRRSSCSSHSASLSSDYSNSKSPSRLSPKHREDGPKGNSARSSRSPSSSSPRRSASPHQNGHKGSAQNGRHSHGPALEEPTDRPASPSPSPRPRGRTDPPSPRTRGGRHGARSPSLERAKHGHRHRSRSASPPRHRGQAPRLPAPAGLSPTGYSSDSEGSVCSHPLSPDRTHGAHAKKVKERHHRGRPNSSSESSAKHSRHGASERRKSPSHSTGHRSTSWSSSGSLSKSRSRSRDKRAARSRSRSPSQKKTASREKDNEPRTRHSDPDPARARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSLSTYSYSRSRSRSYDTYSTSRSRSRTRSPPSRSRSPPSRSPSYNSRSSSESAGF", "length": 626, "header": "tr|A0A8V1AE49-1|A0A8V1AE49_CHICK Computationally mapped isoform of Serine/arginine repetitive matrix 3 OS=Gallus gallus OX=9031 GN=SRRM3 PE=4 SV=1 CANONICAL=A0A8V1AL85-1" }, "locus": { "chromosome": "19", "start_pos": 4762789, "end_pos": 4745971, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071601.1", "url": "https://www.ensembl.org/id/ENSGALT00010071601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044291.1", "url": "https://www.ensembl.org/id/ENSGALP00010044291.1" } ] } }, { "isoform_ac": "A0A8V1AL85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85/entry#A0A8V1AL85-1", "sequence": { "sequence": "MALYNNGANVPSPQEASNGFSQPGASGTWHKAEEEVRLVEPSLVKKAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDQHGRQIVIENHHGLDGEEYTAQYPEYGEGCLLQCDCSAECYRDDSSHREYRLKRRSSSSTSPPPKKKKKKKSGHRRNRKKRKPGSERSCDSSSPIRKEKKKKTGKKHRRDRSESGSRKKRRHRSRSPKNKRKEKNKERKRSRSASPAWRSHRRSSCSSHSASLSSDYSNSKSPSRLSPKHREDGPKGNSARSSRSPSSSSPRRSASPHQNGHKGSAQNGRHSHGPALEEPTDKRPASPSPSPRPRGRTDPPSPRTRGGRHGARSPSLERAKHGHRHRSRSASPPRHRGQAPRLPAPAGLSPTGYSSDSEGSVCSHPLSPDRTHGAHAKKVKERHHRGRPNSSSESSAKHSRHGASERRKSPSHSTGHRSTSWSSSGSLSKSRSRSRDKRAARSRSRSPSQKKTASREKDNEPRTRHSDPDPARARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSLSTYSYSRSRSRSYDTYSTSRSRSRTRSPPSRSRSPPSRSPSYNSRSSSESAGF", "length": 627, "header": "tr|A0A8V1AL85-1|A0A8V1AL85_CHICK Isoform 1 of Serine/arginine repetitive matrix 3 OS=Gallus gallus OX=9031 GN=SRRM3 PE=4 SV=1 CANONICAL=A0A8V1AL85-1" }, "locus": { "chromosome": "19", "start_pos": 4762789, "end_pos": 4745971, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071600.1", "url": "https://www.ensembl.org/id/ENSGALT00010071600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044290.1", "url": "https://www.ensembl.org/id/ENSGALP00010044290.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A6NNA2-1", "protein_name": "Serine/arginine repetitive matrix protein 3", "gene_name": "SRRM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSTVNNGAASMQSTPDAANGFPQPSSSSGTWPRAEEELRAAEPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEGAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSAASVLFHTTGPAPLPPPAA", "length": 597 }, "evidence": [ { "id": "A0A8V1AL85", "url": "https://omabrowser.org/oma/group/A0A8V1AL85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZQH1-1", "protein_name": "Serine/arginine repetitive matrix protein 3", "gene_name": "Srrm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTVNNGATSMPAPPDAANGFPQPGGSSGSWPRAEEELRAAEPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTKEDRPGAHIVAETPRRMEGLEPGLEYPPFDEDDGPVDCDCPVACYRGHRGYRTKHWSSSSASPPPKKKKKKKGSHRRSRKKRRLESECSCGSASPLRKKKRSVKKHRRDRSDSGSRRKRRYRSRSLKSKRKEKIKERKRPHTESPGRRSHHHSSVSSHSPSVSSHYSDSGSPNRLSPKHRDDGRKTGSQRSSGSRSLSPSGGSGWGSPQQNGGSRQRSGAHGGRPGSAHSPPDKPSSPRACDKAAAAPTPPARGKDSQSPRSAPSSQGRGGRAAGGTARRRRRRRRRRRSRSSANAPRRRGRRRAKPAPPRGSSRSLSGAHSSSDSGGGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGNSSSRSPGPHPGSWSSSRSPSKSRSRSPDKRTRSPSLSPSPKKPLGRDKDSEGRARHAEAEAARTRRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSSRSRSRSPSPGHSHGSYSSRSHGTRSRSCSASRSRSPSYHSRSSSESGGF", "length": 648 }, "evidence": [ { "id": "A0A8V1AL85", "url": "https://omabrowser.org/oma/group/A0A8V1AL85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80WV7-1", "protein_name": "Serine/arginine repetitive matrix protein 3", "gene_name": "Srrm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTVNNGATGMPAPPDAANGFPQPGASSGSWPRAEEELRAAEPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGAHIVAETPRRMEGLEPGLEYPPFDEDDGPVDCDCPVSCYRGHRGYRTKHWSSSSASPPPKKKKKKKGSHRRSRKKRRLESECSCGSASPLRKKKKNVKKHRRDRSDSGSRRKRRYRSRSLKSKRKEKNKERKRPHTESPGRRFHHHSSASSHSPSMSSHYSDSGSPSRLSPKHRDDGRKTGSQRSSGSRSPSPSGGSGWGSPQQNGGSRQRSGAHGGRPGSAHSPPDKPSSPRACDKAAAAPTPPARGKDSQSPRSAPSSQGRGGRAAGGTARRRRRRRRRRRSRSSANAPRRRGRRRTKPAPPRGSSRSLSGAHSSSDSGGGAPGPGPEPCSERGHGGHGKRAKERPPRARPASTSPSPGTRGRRGGPEGNSSSRSPGPHQGSWSSSRSPSKSHSRSPDKRTRSPSLSPSPKKPLGRDKDSEGRARHAEAEAARTRRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSTDYSSRSHSRSPSPGHSHGSYSSRSHGTRSRSCSASRSRSPSYHSRSSSESGGF", "length": 648 }, "evidence": [ { "id": "A0A8V1AL85", "url": "https://omabrowser.org/oma/group/A0A8V1AL85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of insulin secretion", "id": "GO:0046676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" } ], "pmid": "" }, { "name": "negative regulation of glucagon secretion", "id": "GO:0070093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070093", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL85" }, { "id": "SM01115", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CWF21", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 97, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 443, "end_pos": 445 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL94-1", "uniprot_ac": "A0A8V1AL94", "uniprot_id": "A0A8V1AL94_CHICK", "mass": { "chemical_mass": 36448.0, "monoisotopic_mass": 36448.0 }, "refseq": {}, "gene_names": [ { "name": "LYSMD1", "type": "recommended", "evidence": [ { "id": "A0A8V1AL94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94" } ] } ], "protein_names": [ { "name": "LysM and putative peptidoglycan-binding domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V1AL94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LYSMD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94", "locus": {} } ], "crossref": [ { "id": "A0A8V1AL94", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL94", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL94", "url": "https://www.orthodb.org/?gene=A0A8V1AL94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AL94", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPRPSRAEGSPAAPRPTLWAQLPFTSRSSAAALRPPGCNWPTAPPRVSSARGRRGAVRASPAPQCAPVRGGTRPHPPPPVCQREPEGKRAGVGGLTCSTASCPASSPSRLKDMAAPSAAPPSPWGAPAVRFRVLRPVVPRADAGTNGERGAAEPRGTTGAVVLRRTSALGPEGRGTTTPSGLRAGPERGRGAAGRPAMAGGREHRVGPGDTLPGLALRYGVTMEQIKRANRLYTSDTIFLKPTLLIPPPGCPTEAPMGSAPSDPTTATAATTTAAPPHDLTATDFLRRLDADIGRSKAAVVEQRLRTGVPEAAVPLPPPGPSLRGPQLGAQPLTRTRRAAALRDTEDEIFTL", "length": 353, "header": "tr|A0A8V1AL94-1|A0A8V1AL94_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LYSMD1 PE=4 SV=1 CANONICAL=A0A8V1AL94-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AL94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94/entry#A0A8V1AL94-1", "sequence": { "sequence": "MGPRPSRAEGSPAAPRPTLWAQLPFTSRSSAAALRPPGCNWPTAPPRVSSARGRRGAVRASPAPQCAPVRGGTRPHPPPPVCQREPEGKRAGVGGLTCSTASCPASSPSRLKDMAAPSAAPPSPWGAPAVRFRVLRPVVPRADAGTNGERGAAEPRGTTGAVVLRRTSALGPEGRGTTTPSGLRAGPERGRGAAGRPAMAGGREHRVGPGDTLPGLALRYGVTMEQIKRANRLYTSDTIFLKPTLLIPPPGCPTEAPMGSAPSDPTTATAATTTAAPPHDLTATDFLRRLDADIGRSKAAVVEQRLRTGVPEAAVPLPPPGPSLRGPQLGAQPLTRTRRAAALRDTEDEIFTL", "length": 353, "header": "tr|A0A8V1AL94-1|A0A8V1AL94_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 1 OS=Gallus gallus OX=9031 GN=LYSMD1 PE=4 SV=1 CANONICAL=A0A8V1AL94-1" }, "locus": { "chromosome": "25", "start_pos": 2632551, "end_pos": 2630836, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069246.1", "url": "https://www.ensembl.org/id/ENSGALT00010069246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042688.1", "url": "https://www.ensembl.org/id/ENSGALP00010042688.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL94" }, { "id": "PS51782", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 247, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AL95-1", "uniprot_ac": "A0A8V1AL95", "uniprot_id": "A0A8V1AL95_CHICK", "mass": { "chemical_mass": 50638.0, "monoisotopic_mass": 50638.0 }, "refseq": {}, "gene_names": [ { "name": "COL26A1", "type": "recommended", "evidence": [ { "id": "A0A8V1AL95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ] } ], "protein_names": [ { "name": "Collagen type XXVI alpha 1 chain", "type": "synonym", "evidence": [ { "id": "A0A8V1AL95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL26A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95", "locus": { "chromosome": "19", "start_pos": 4169442, "end_pos": 4010545, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029264", "url": "https://www.ensembl.org/id/ENSGALG00010029264" } ] } } ], "crossref": [ { "id": "A0A8V1AL95", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AL95", "database": "AlphaFoldDB", "categories": [] }, { "id": "417504", "url": "https://www.ncbi.nlm.nih.gov/gene/417504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ABT1", "url": "https://www.orthodb.org/?gene=A0A8V1ABT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AL95", "url": "https://www.orthodb.org/?gene=A0A8V1AL95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ABT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ABT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AL95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFALFLSWCCCLHGCALGTGFLYQFPASTLQHNYPEQSSGSPGSGFASRRHWCHYTVTRTVSCQVQNGSETVIQRVYQSCRWPGPCANLVSYRTLIRPTYKMSYRTVTTLEWRCCPGFTGSNCEEECMNCTRLADMTERLNTLEAKILLLEAAERSPPLENNLPITGTTATWYDDLLPDAFPLLNPGTVLRKTVGPVDPKGHRGAEEQLIPQGMPGQVGPPGPVGPTGLPGPPGPKGEKGQPGERGPAGPPGLLGPQGPRGLPGETGIPGPPGPPGPPATPSLPLTFQQGVLYSLQPTAEKENGEPQLASTVIDTIMAGLPGPRGAPGPVGPPGPPGASGPKGPPGPIGVPGSQGLPGSPGQPGPKGSKGDRGERGQAGLTGERGIKGFPGEPGKKGEEGDKGADGEGVQQLREALKILAERVLILEHMIGIHGSGQDVIPGSPLRSSIKIKRGGPQQPHAYQILSSLLDDSEAKRRSSRMK", "length": 483, "header": "tr|A0A8V1AL95-1|A0A8V1AL95_CHICK Isoform 1 of Collagen type XXVI alpha 1 chain OS=Gallus gallus OX=9031 GN=COL26A1 PE=4 SV=1 CANONICAL=A0A8V1AL95-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ABT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95/entry#A0A8V1ABT1-1", "sequence": { "sequence": "MRFALFLSWCCCLHGCALGTGFLYQFPASTLQHNYPEQSSGSPGSGFASRRHWCHYTVTRTVSCQVQNGSETVIQRVYQSCRWPGPCANLVSYRTLIRPTYKMSYRTVTTLEWRCCPGFTGSNCEEGSLGRQHGRSSSRDQCMNCTRLADMTERLNTLEAKILLLEAAERSPPLENNLPITGTTATWYDDLLPDAFPLLNPGTVLRKTVGPVDPKGHRGAEEQLIPQGMPGQVGPPGPVGPTGLPGPPGPKGEKGQPGERGPAGPPGLLGPQGPRGLPGETGIPGPPGPPGPPATPSLPLTFQQGVLYSLQPTAEKENGEPQLASTVIDTIMAGLPGPRGAPGPVGPPGPPGASGPKGPPGPIGVPGSQGLPGSPGQPGPKGSKGDRGERGEPGKKGEEGDKGADGEGVQQLREALKILAERVLILEHMIGIHGSGQDVIPGSPLRSSIKIKRGGPQQPHAYQILSSLLDDSEAKRRSSRMK", "length": 482, "header": "tr|A0A8V1ABT1-1|A0A8V1ABT1_CHICK Computationally mapped isoform of Collagen type XXVI alpha 1 chain OS=Gallus gallus OX=9031 GN=COL26A1 PE=4 SV=1 CANONICAL=A0A8V1AL95-1" }, "locus": { "chromosome": "19", "start_pos": 4165492, "end_pos": 4010691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070762.1", "url": "https://www.ensembl.org/id/ENSGALT00010070762.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043453.1", "url": "https://www.ensembl.org/id/ENSGALP00010043453.1" } ] } }, { "isoform_ac": "A0A8V1AL95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95/entry#A0A8V1AL95-1", "sequence": { "sequence": "MRFALFLSWCCCLHGCALGTGFLYQFPASTLQHNYPEQSSGSPGSGFASRRHWCHYTVTRTVSCQVQNGSETVIQRVYQSCRWPGPCANLVSYRTLIRPTYKMSYRTVTTLEWRCCPGFTGSNCEEECMNCTRLADMTERLNTLEAKILLLEAAERSPPLENNLPITGTTATWYDDLLPDAFPLLNPGTVLRKTVGPVDPKGHRGAEEQLIPQGMPGQVGPPGPVGPTGLPGPPGPKGEKGQPGERGPAGPPGLLGPQGPRGLPGETGIPGPPGPPGPPATPSLPLTFQQGVLYSLQPTAEKENGEPQLASTVIDTIMAGLPGPRGAPGPVGPPGPPGASGPKGPPGPIGVPGSQGLPGSPGQPGPKGSKGDRGERGQAGLTGERGIKGFPGEPGKKGEEGDKGADGEGVQQLREALKILAERVLILEHMIGIHGSGQDVIPGSPLRSSIKIKRGGPQQPHAYQILSSLLDDSEAKRRSSRMK", "length": 483, "header": "tr|A0A8V1AL95-1|A0A8V1AL95_CHICK Isoform 1 of Collagen type XXVI alpha 1 chain OS=Gallus gallus OX=9031 GN=COL26A1 PE=4 SV=1 CANONICAL=A0A8V1AL95-1" }, "locus": { "chromosome": "19", "start_pos": 4165492, "end_pos": 4010691, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070760.1", "url": "https://www.ensembl.org/id/ENSGALT00010070760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043451.1", "url": "https://www.ensembl.org/id/ENSGALP00010043451.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 228, "start_aa": "Thr", "end_pos": 228, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr228", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AL95", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AL95", "database": "UniProtKB", "url": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALA7-1", "uniprot_ac": "A0A8V1ALA7", "uniprot_id": "A0A8V1ALA7_CHICK", "mass": { "chemical_mass": 64916.0, "monoisotopic_mass": 64916.0 }, "refseq": { "ac": "XP_425416", "name": "WSC domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425416" }, "gene_names": [ { "name": "WSCD1", "type": "recommended", "evidence": [ { "id": "A0A8V1ALA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7" } ] }, { "name": "WSCD1", "type": "synonym", "evidence": [ { "id": "XP_425416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425416" } ] } ], "protein_names": [ { "name": "WSC domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1ALA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7/entry#names_and_taxonomy" } ] }, { "name": "WSC domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_425416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425416" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_425416.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425416" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WSCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7", "locus": { "chromosome": "19", "start_pos": 10144794, "end_pos": 10120836, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029269", "url": "https://www.ensembl.org/id/ENSGALG00010029269" } ] } } ], "crossref": [ { "id": "A0A8V1ALA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "427842", "url": "https://www.ncbi.nlm.nih.gov/gene/427842", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KYAGHLG", "url": "https://omabrowser.org/oma/group/KYAGHLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALA7", "url": "https://www.orthodb.org/?gene=A0A8V1ALA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45964:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45964:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425416", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKVFFRLQKFLRRTQFLLFFLTAAYLMAGSLLLLQRARLAAQQGPRGSSGLALPGPDMGLGAKAADPHLAQSPGAQLPMGVDTLPEVELRHSPRWMASRNSELRWLRRRWFHRFIGDQEPMQTAGLRAMRGTAEHKGTYVGCFSDDSRERTLKGAVFYDLRKMTVAHCQEACAERAYAYAGLAYGAECYCGNKLPATTSRPEECNSECKGEKGSVCGGVNRLSVYRVEELQAAAPRRRNVIYRGCFRAPENLTDTFPASLIQPNLTVEMCSEFCSKKEFPLAVIRGRECYCGYPTGHFPLRHGADRRLCSAMPNASSAAAGGYCLAYQTPVQDTRCTDRKFLTTKSKGFIALSSFPGAGNTWARHLIEHATGYYTGSYYFDGALYNKGFKGEKDHWRSRRTICVKTHESGKTEIEMFDSAILLIRNPYKSLMAEFNRKFAGHLGYAADRNWKSKDWPDFVNSYASWWASHVLDWLKYGKRLLVIHYEDLKQSLIPKLKEMVEFLNMTVTEDRLLCVENNRDGNFKRSGAKQKDFEPFTQEMKDLINRYILTVDEALRGRNFTGLPREYVPR", "length": 572, "header": "tr|A0A8V1ALA7-1|A0A8V1ALA7_CHICK Isoform 1 of WSC domain containing 1 OS=Gallus gallus OX=9031 GN=WSCD1 PE=3 SV=1 CANONICAL=A0A8V1ALA7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7/entry#A0A8V1ALA7-1", "sequence": { "sequence": "MAKVFFRLQKFLRRTQFLLFFLTAAYLMAGSLLLLQRARLAAQQGPRGSSGLALPGPDMGLGAKAADPHLAQSPGAQLPMGVDTLPEVELRHSPRWMASRNSELRWLRRRWFHRFIGDQEPMQTAGLRAMRGTAEHKGTYVGCFSDDSRERTLKGAVFYDLRKMTVAHCQEACAERAYAYAGLAYGAECYCGNKLPATTSRPEECNSECKGEKGSVCGGVNRLSVYRVEELQAAAPRRRNVIYRGCFRAPENLTDTFPASLIQPNLTVEMCSEFCSKKEFPLAVIRGRECYCGYPTGHFPLRHGADRRLCSAMPNASSAAAGGYCLAYQTPVQDTRCTDRKFLTTKSKGFIALSSFPGAGNTWARHLIEHATGYYTGSYYFDGALYNKGFKGEKDHWRSRRTICVKTHESGKTEIEMFDSAILLIRNPYKSLMAEFNRKFAGHLGYAADRNWKSKDWPDFVNSYASWWASHVLDWLKYGKRLLVIHYEDLKQSLIPKLKEMVEFLNMTVTEDRLLCVENNRDGNFKRSGAKQKDFEPFTQEMKDLINRYILTVDEALRGRNFTGLPREYVPR", "length": 572, "header": "tr|A0A8V1ALA7-1|A0A8V1ALA7_CHICK Isoform 1 of WSC domain containing 1 OS=Gallus gallus OX=9031 GN=WSCD1 PE=3 SV=1 CANONICAL=A0A8V1ALA7-1" }, "locus": { "chromosome": "19", "start_pos": 10144095, "end_pos": 10128107, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070775.1", "url": "https://www.ensembl.org/id/ENSGALT00010070775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043466.1", "url": "https://www.ensembl.org/id/ENSGALP00010043466.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MJU6-1", "protein_name": "WSC domain containing 1", "gene_name": "WSCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKPFFRLQKFLRRTQFLLFFLTAAYLMTGSLLLLQRARVGLPPGPRAPGPLQALPVAAVALGVGLLDSRALRDGRVSPELLLGVDVLRGPLARPRPGPRWLRSRNSELRQLRRRWFHHFMADPPGPPALSPEAPQPATSSRGTYVGCFSDDGQERTLKGAVFFDLRKMTVSHCQDACAERSYIYAGLEAGAECYCGNRLPAMSVGPEECNHECKGEKSSVCGGVGRLSVYRVEELQPGSRKRRTVTYRGCFRLPENITHAFPDSLVQANVTVETCSGFCSQKEFPLAILRGWECYCAYSTPQFNLRDAVDSSLCGQESEAQRLAEYCEVYQTPVQDTRCTDRRFLPTKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAADRNWKSKEWPDFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRRSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRRPHDPEPFTPEMKDLINGYIRTVDQALRDHNWAGLPREYVPR", "length": 575 }, "evidence": [ { "id": "A0A8V1ALA7", "url": "https://omabrowser.org/oma/group/A0A8V1ALA7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RGL9-1", "protein_name": "WSC domain containing 1", "gene_name": "WSCD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKPFFRLQKFLRRTQFLLFFLTAAYLMTGSLLLLQRARVGLPPGPRAPGPLQALPVAAVALGVGLLDSRALHDPRVSPELLLGVDVLRGPLARPRPGPRWLRSRNSELRQLRRRWFHRFMGDSQGPPALGPEAPRPATSSRGTYVGCFSDNGQERTLKGAVFFDLRKMTVPHCQDACAERSYLYAGLEAGAECYCGNRLPVVSVGPEECNHECKGEKSSVCGGVGRLSVYRVEELQPSSRKRRTVTYRGCFRLPGNVTHAFADSLVQANVTVETCSGFCSQKEFPLAVLRGWECYCAYPTPQFNLRDAVDSSLCGQESEAQRLAEYCEVYQTPVQDTRCTDRRFLPTKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAADRNWKSKEWPDFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRRSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRRPQDPEPFTPEMKDLINGYIRTVDQALRDHNWAGLPREYVPR", "length": 575 }, "evidence": [ { "id": "A0A8V1ALA7", "url": "https://omabrowser.org/oma/group/A0A8V1ALA7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q505J3-1", "protein_name": "Sialate:O-sulfotransferase 1", "gene_name": "Wscd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKPFFRLQKFLRRTQFLLLFLTAAYLMTGSLLLLQRARVALPQALRAPGSLQALPVATVALGVGLLDSRSLHDPHSSPDLLLDVDTLRSPLARVPPGIRWPRRNRSSLRRRWLHHLTSDPQGPPTLGPEASGPASHNQGNYLGCFSEEGQERTLKGAVFYDLRKMTVSHCQEACAERSYVYAGLEAGAECYCGNRLPATRVSLKECNQECKGEKGSMCGALHRLSVYSVGLQQSGAKKRWTATYRGCFPLPENITRTFSSSMTQANVTVETCSGFCSQKEFPLAILRGWACYCAYPTPQFSLRDAVDGALCSQGTEAQGLPGYCEVYQTPVQDTRCTDRKFLPNKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAPDRNWKSKEWPDFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRHSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRHPHDQEPFTPEMKDLINGYIRTVDQALRDHNWAGLPREYVPR", "length": 572 }, "evidence": [ { "id": "A0A8V1ALA7", "url": "https://omabrowser.org/oma/group/A0A8V1ALA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q658N2-1", "protein_name": "Sialate:O-sulfotransferase 1", "gene_name": "WSCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKPFFRLQKFLRRTQFLLFFLTAAYLMTGSLLLLQRVRVALPQGPRAPGPLQTLPVAAVALGVGLLDSRALHDPRVSPELLLGVDMLQSPLTRPRPGPRWLRSRNSELRQLRRRWFHHFMSDSQGPPALGPEAARPAIHSRGTYIGCFSDDGHERTLKGAVFYDLRKMTVSHCQDACAERSYVYAGLEAGAECYCGNRLPAVSVGLEECNHECKGEKGSVCGAVDRLSVYRVDELQPGSRKRRTATYRGCFRLPENITHAFPSSLIQANVTVGTCSGFCSQKEFPLAILRGWECYCAYPTPRFNLRDAMDSSVCGQDPEAQRLAEYCEVYQTPVQDTRCTDRRFLPNKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAADRNWKSKEWPDFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRRSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRRSHDPEPFTPEMKDLINGYIRTVDQALRDHNWTGLPREYVPR", "length": 575 }, "evidence": [ { "id": "A0A8V1ALA7", "url": "https://omabrowser.org/oma/group/A0A8V1ALA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80XH4-1", "protein_name": "Sialate:O-sulfotransferase 1", "gene_name": "Wscd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKPFFRLQKFLRRTQFLLLFLTAAYLMTGSLLLLQRARVALPQALRAPGSLQALPVATVALGVGLLDGRSLRDPHSSPDLLLDVDTLRSPLARLPPGIRWPRRNRSSLRRRWLHHLTSDPQGPPTLSPEASGPANHNRGNYLGCFSEEGQERTLKGAVFYDLRKMTVSHCQDACAERSYVYAGLEAGAECYCGNRLPATRVSLKECNQECKGEKGSMCGAVRRLSVYSVGLQQPGSKKRRTATYRGCFPLPENVTHTFSSSMTQANMTVETCSGFCSQKEFPLAILRGWDCYCAYPTPQFSLRDAVDGALCSQAPETQGLPGYCEVYQTPVQDTRCTDRKFLPDKSKVFVALSSFPGAGNTWARHLIEHATGFYTGSYYFDGTLYNKGFKGEKDHWRSRRTICVKTHESGRREIEMFDSAILLIRNPYRSLVAEFNRKCAGHLGYAPDRNWKSKEWPEFVNSYASWWSSHVLDWLKYGKRLLVVHYEELRHSLVPTLREMVAFLNVSVSEERLLCVENNKEGSFRRRGRRPHDQEPFTPEMKDLINGYIRTVDQALRDHNWAGLPREYVPR", "length": 572 }, "evidence": [ { "id": "A0A8V1ALA7", "url": "https://omabrowser.org/oma/group/A0A8V1ALA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALA7" }, { "id": "PS51212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WSC", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 229, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 561, "end_pos": 563 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALB5-1", "uniprot_ac": "A0A8V1ALB5", "uniprot_id": "A0A8V1ALB5_CHICK", "mass": { "chemical_mass": 19956.0, "monoisotopic_mass": 19956.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "TRAFD1/XAF1 zinc finger domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ALB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5", "locus": {} } ], "crossref": [ { "id": "A0A8V1ALB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16295:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16295:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ALB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEGTRFCKNCKRDVSTANFSLHEAHCLRFLTLCSECDEPVARKDMKDHQTEAHKQVRCNLCCRSMQQYQLEHHKTKECHKRAMKCKICELEMPFNKLQEHLNTCASRTERCWECNKYVMYKDQKKHKDICQNSGLSYYKDVNFQTRNAYTNAKFIDPTVIISGCKQPV", "length": 169, "header": "tr|A0A8V1ALB5-1|A0A8V1ALB5_CHICK Isoform 1 of TRAFD1/XAF1 zinc finger domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ALB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5/entry#A0A8V1ALB5-1", "sequence": { "sequence": "MTEGTRFCKNCKRDVSTANFSLHEAHCLRFLTLCSECDEPVARKDMKDHQTEAHKQVRCNLCCRSMQQYQLEHHKTKECHKRAMKCKICELEMPFNKLQEHLNTCASRTERCWECNKYVMYKDQKKHKDICQNSGLSYYKDVNFQTRNAYTNAKFIDPTVIISGCKQPV", "length": 169, "header": "tr|A0A8V1ALB5-1|A0A8V1ALB5_CHICK Isoform 1 of TRAFD1/XAF1 zinc finger domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ALB5-1" }, "locus": { "chromosome": "19", "start_pos": 10254812, "end_pos": 10250246, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070785.1", "url": "https://www.ensembl.org/id/ENSGALT00010070785.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043476.1", "url": "https://www.ensembl.org/id/ENSGALP00010043476.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALB5" }, { "id": "PF21366", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRAFD1/XAF1 zinc finger", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 131, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALC1-1", "uniprot_ac": "A0A8V1ALC1", "uniprot_id": "A0A8V1ALC1_CHICK", "mass": { "chemical_mass": 61629.0, "monoisotopic_mass": 61629.0 }, "refseq": {}, "gene_names": [ { "name": "GTPBP3", "type": "recommended", "evidence": [ { "id": "A0A8V1ALC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ] } ], "protein_names": [ { "name": "5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V1ALC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ALC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1/entry#names_and_taxonomy" } ] }, { "name": "tRNA modification GTPase GTPBP3, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8V1ALC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "GTPase component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1#function" }, { "database": "UniProtKB", "id": "ARBA00059757", "url": "https://www.uniprot.org/uniprotkb/ARBA00059757#function" }, { "database": "UniProtKB", "id": "A0A8V1A9T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9T2#function" }, { "database": "UniProtKB", "id": "A0A8V1AF30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF30#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTPBP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1", "locus": { "chromosome": "28", "start_pos": 3884897, "end_pos": 3866899, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028605", "url": "https://www.ensembl.org/id/ENSGALG00010028605" } ] } } ], "crossref": [ { "id": "A0A8V1ALC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04164", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04164", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14858", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14858", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A9T2", "url": "https://www.orthodb.org/?gene=A0A8V1A9T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AF30", "url": "https://www.orthodb.org/?gene=A0A8V1AF30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALC1", "url": "https://www.orthodb.org/?gene=A0A8V1ALC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42714", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42714", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42714:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42714:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10396", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10396", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A9T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A9T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AF30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AF30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRRALSAAGRRCAQRLCSVAPGDTIFAVSSGHGRCGVAVIRSSGPGSGGALRSLTGSPELPPPRVMALRRIRDPHTAELLDHGLVVWFPGPHSFTGEDCAELHVHGGPAVVSGVLRALGRLSGLRPAEPGEFTRRAFHRGKLDLTAAEGLRDLIHAETEAQRQQALRQMEGELGRLYQQWGETLTQALAHIEAYIDFSEDDNVEEEVLSQVDAAVRALERQIAAHLQDGRRGEMLRSGVRAVIAGPPNVGKSSLLNLLCQRPAAIVSPVAGTTRDVVEVSLNVSGYPVVLSDTAGLRDATDPIEQEGVSRARERLQHADLVLAVLDATTVPTDPAELGAALGSLVPPATPCILVLNKADLLGGHTGALCDSCTRGPPLPPTTLLSCKTGEGTERLLQLLGEQLAQLCGDPLAGSPSLTQSRHSTQLGGCMAALALYRQQQDVGMAAEQLRLARRHLGRITGHVGAEDILDVIFRDFCIGAPAAPWWCRTAHPWPSAPAGSAPAPAWPYPAPLRPCCCSAPAPSSAASPCSAAPAAAPSRLRGVEGWGALRWTPTPHPHPPPRGAAQPRGTPCVGSLRVTGDPRA", "length": 586, "header": "tr|A0A8V1ALC1-1|A0A8V1ALC1_CHICK Isoform 1 of 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial OS=Gallus gallus OX=9031 GN=GTPBP3 PE=3 SV=1 CANONICAL=A0A8V1ALC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A9T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1/entry#A0A8V1A9T2-1", "sequence": { "sequence": "MYTGTNTGTYSKTCTRCAQRLCSVAPGDTIFAVSSGHGRCGVAVIRSSGPGSGGALRSLTGSPELPPPRVMALRRIRDPHTAELLDHGLVVWFPGPHSFTGEDCAELHVHGGPAVVSGVLRALGRLSGLRPAEPGEFTRRAFHRGKLDLTAAEGLRDLIHAETEAQRQQALRQMEGELGRLYQQWGETLTQALAHIEAYIDFSEDDNVEEEVLSQVDAAVRALERQIAAHLQDGRRGEMLRSGVRAVIAGPPNVGKSSLLNLLCQRPAAIVSPVAGTTRDVVEVSLNVSGYPVVLSDTAGLRDATDPIEQEGVSRARERLQHADLVLAVLDATTVPTDPAELGAALGSLVPPATPCILVLNKADLLGGHTGALCDSCTRGPPLPPTTLLSCKTGEGTERLLQLLGEQLAQLCGDPLAGSPSLTQSRHSTQLGGCMAALALYRQQQDVGMAAEQLRLARRHLGRITGHVGAEDILDVIFRDFCIASSAPPDRPAAAAAPPAAACPAPASRGSS", "length": 512, "header": "tr|A0A8V1A9T2-1|A0A8V1A9T2_CHICK Computationally mapped isoform of 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial OS=Gallus gallus OX=9031 GN=GTPBP3 PE=3 SV=1 CANONICAL=A0A8V1ALC1-1" }, "locus": { "chromosome": "28", "start_pos": 3875185, "end_pos": 3866972, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069280.1", "url": "https://www.ensembl.org/id/ENSGALT00010069280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042722.1", "url": "https://www.ensembl.org/id/ENSGALP00010042722.1" } ] } }, { "isoform_ac": "A0A8V1AF30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1/entry#A0A8V1AF30-1", "sequence": { "sequence": "MALRRALSAAGRRCAQRLCSVAPGDTIFAVSSGHGRCGVAVIRSSGPGSGGALRSLTGSPELPPPRVMALRRIRDPHTAELLDHGLVVWFPGPHSFTGEDCAELHVHGGPAVVSGVLRALGRLSGLRPAEPGEFTRRAFHRGKLDLTAAEGLRDLIHAETEAQRQQALRQMEGELGRLYQQWGETLTQALAHIEAYIDFSEDDNVEEEVLSQVDAAVRALERQIAAHLQDGRRGEMLRSGVRAVIAGPPNVGKSSLLNLLCQRPAAIVSPVAGTTRDVVEVSLNVSGYPVVLSDTAGLRDATDPIEQEGVSRARERLQHADLVLAVLDATTVPTDPAELGAALGSLVPPATPCILVLNKADLLGGHTGALCDSCTRGPPLPPTTLLSCKTGEGTERLLQLLGEQLAQLCGDPLAGSPSLTQSRHSTQLGGCMAALALYRQQQDVGMAAEQLRLARRHLGRITGHVGAEDILDVIFRDFCIEIAAGALSFNPAAAAAPDRAEQTAESSPTRR", "length": 511, "header": "tr|A0A8V1AF30-1|A0A8V1AF30_CHICK Computationally mapped isoform of 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial OS=Gallus gallus OX=9031 GN=GTPBP3 PE=3 SV=1 CANONICAL=A0A8V1ALC1-1" }, "locus": { "chromosome": "28", "start_pos": 3884897, "end_pos": 3870217, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069282.1", "url": "https://www.ensembl.org/id/ENSGALT00010069282.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042724.1", "url": "https://www.ensembl.org/id/ENSGALP00010042724.1" } ] } }, { "isoform_ac": "A0A8V1ALC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1/entry#A0A8V1ALC1-1", "sequence": { "sequence": "MALRRALSAAGRRCAQRLCSVAPGDTIFAVSSGHGRCGVAVIRSSGPGSGGALRSLTGSPELPPPRVMALRRIRDPHTAELLDHGLVVWFPGPHSFTGEDCAELHVHGGPAVVSGVLRALGRLSGLRPAEPGEFTRRAFHRGKLDLTAAEGLRDLIHAETEAQRQQALRQMEGELGRLYQQWGETLTQALAHIEAYIDFSEDDNVEEEVLSQVDAAVRALERQIAAHLQDGRRGEMLRSGVRAVIAGPPNVGKSSLLNLLCQRPAAIVSPVAGTTRDVVEVSLNVSGYPVVLSDTAGLRDATDPIEQEGVSRARERLQHADLVLAVLDATTVPTDPAELGAALGSLVPPATPCILVLNKADLLGGHTGALCDSCTRGPPLPPTTLLSCKTGEGTERLLQLLGEQLAQLCGDPLAGSPSLTQSRHSTQLGGCMAALALYRQQQDVGMAAEQLRLARRHLGRITGHVGAEDILDVIFRDFCIGAPAAPWWCRTAHPWPSAPAGSAPAPAWPYPAPLRPCCCSAPAPSSAASPCSAAPAAAPSRLRGVEGWGALRWTPTPHPHPPPRGAAQPRGTPCVGSLRVTGDPRA", "length": 586, "header": "tr|A0A8V1ALC1-1|A0A8V1ALC1_CHICK Isoform 1 of 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial OS=Gallus gallus OX=9031 GN=GTPBP3 PE=3 SV=1 CANONICAL=A0A8V1ALC1-1" }, "locus": { "chromosome": "28", "start_pos": 3875716, "end_pos": 3870217, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069276.1", "url": "https://www.ensembl.org/id/ENSGALT00010069276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042718.1", "url": "https://www.ensembl.org/id/ENSGALP00010042718.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" }, { "name": "tRNA 5-taurinomethyluridine synthase activity", "id": "GO:0160236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" }, { "name": "GTPBP3-MTO1 complex", "id": "GO:7770010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:7770010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "tRNA wobble uridine modification", "id": "GO:0002098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" }, { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" }, { "name": "mitochondrial tRNA wobble uridine modification", "id": "GO:0070899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" }, { "name": "mitochondrial tRNA modification", "id": "GO:0070900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": "RAP2B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBX5" } ] } ] }, { "uniprot_ac": "A0A8V0XC33", "gene_name": "RAB23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { 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"recommended", "evidence": [ { "id": "A0A8V1ALD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7" } ] } ], "protein_names": [ { "name": "Mitochondrial ribosomal protein S21", "type": "synonym", "evidence": [ { "id": "A0A8V1ALD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPS21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7", "locus": { "chromosome": "25", "start_pos": 2305740, "end_pos": 2308372, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028609", "url": "https://www.ensembl.org/id/ENSGALG00010028609" } ] } } ], "crossref": [ { "id": "A0A8V1ALD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALD7", "url": "https://www.orthodb.org/?gene=A0A8V1ALD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21109:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21109:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ALD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVGWGECFGVRGCSFCLLGLWCPLNLAPIRVLVSPLGLVSPPPPPPHCGSVALLKLLSPKSDVSPLGTWCPLGSVVLFEPSVPTWGSGVIPEPWGHCPLDPTPPPRWSSAPPGASVTLVPGATRGPHAIRSSAVSIPTVPWSSVPPGPVLVSPLWAQCPPFGLSVPPLGSMSLSHSAPYQDLCLLLGLVPFGPHNLRAQCLPWSRHPLVVSPASRGDPYPGPHRDTRRRSLSPDPAPFVHATPPVTRATSPAPFLIHAPCAKPRPSTWGRWRFPVPGRTEVSGGVVVSRGPGGSWGTGRSRGGSVPLRSPSAMANHLRFIGRTVMVQNGNVDAAYGALSRILSQDGIIESVKQRRYYEKPCRKRQRLAYEACRRVYNAEMARKISFLARKSRMDPWLGC", "length": 400, "header": "tr|A0A8V1ALD7-1|A0A8V1ALD7_CHICK Isoform 1 of Mitochondrial ribosomal protein S21 OS=Gallus gallus OX=9031 GN=MRPS21 PE=1 SV=1 CANONICAL=A0A8V1ALD7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7/entry#A0A8V1ALD7-1", "sequence": { "sequence": "MGVGWGECFGVRGCSFCLLGLWCPLNLAPIRVLVSPLGLVSPPPPPPHCGSVALLKLLSPKSDVSPLGTWCPLGSVVLFEPSVPTWGSGVIPEPWGHCPLDPTPPPRWSSAPPGASVTLVPGATRGPHAIRSSAVSIPTVPWSSVPPGPVLVSPLWAQCPPFGLSVPPLGSMSLSHSAPYQDLCLLLGLVPFGPHNLRAQCLPWSRHPLVVSPASRGDPYPGPHRDTRRRSLSPDPAPFVHATPPVTRATSPAPFLIHAPCAKPRPSTWGRWRFPVPGRTEVSGGVVVSRGPGGSWGTGRSRGGSVPLRSPSAMANHLRFIGRTVMVQNGNVDAAYGALSRILSQDGIIESVKQRRYYEKPCRKRQRLAYEACRRVYNAEMARKISFLARKSRMDPWLGC", "length": 400, "header": "tr|A0A8V1ALD7-1|A0A8V1ALD7_CHICK Isoform 1 of Mitochondrial ribosomal protein S21 OS=Gallus gallus OX=9031 GN=MRPS21 PE=1 SV=1 CANONICAL=A0A8V1ALD7-1" }, "locus": { "chromosome": "25", "start_pos": 2308173, "end_pos": 2305829, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069291.1", "url": "https://www.ensembl.org/id/ENSGALT00010069291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042733.1", "url": "https://www.ensembl.org/id/ENSGALP00010042733.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AN43-1", "uniprot_ac": "A0A8V1AN43", "uniprot_id": "A0A8V1AN43_CHICK", "mass": { "chemical_mass": 100001.0, "monoisotopic_mass": 100001.0 }, "refseq": {}, "gene_names": [ { "name": "MYCBPAP", "type": "recommended", "evidence": [ { "id": "A0A8V1AN43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43" } ] } ], "protein_names": [ { "name": "Radical S-adenosyl methionine domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AN43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYCBPAP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43", "locus": { "chromosome": "18", "start_pos": 10959552, "end_pos": 10969896, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029644", "url": "https://www.ensembl.org/id/ENSGALG00010029644" } ] } } ], "crossref": [ { "id": "A0A8V1AN43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AN43", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALE0", "url": "https://www.orthodb.org/?gene=A0A8V1ALE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN43", "url": "https://www.orthodb.org/?gene=A0A8V1AN43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48421:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48421:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ALE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGGIEGIEGSSDPTGSVVLCNAPLRWEAVCAGGTFVGNCAAVVRSLQLRAPRPPRDAGRIPVRRKFLVRKCQPRETRSAGQLLVARPAFPRAAREPLRFSGRVELQGLPLASGCGRTGLSGLPCRLVVFVGPALFNGGCGQILPHHVLGSLQELRMEASARGNAQIADFIQAPHQNVAAAVLKEERGGKAKRKFNRTPTSEHKALQNWHRNMAIRRRQETFLGEVLQKPENELLMSISEDYRQIQEERELIDRSLPALFPGKGYRAGSEFWSQPERVGDELTGLTVTLTRRERGCPEPVTHVGKPHTVRMETGVKPPKRSPFHLTWDKSLFLKQRRQELKSILEELDFYQPDLDGLEVIGKGRPFTSVSAQPLPRSAAFEDSETSSDSLEDRCSVVPETVLGPSLDFCGQPACWINCIASCRDEVGIAARLTFETVVGEKAESFLTVSNDGTAAVWYNWRRLLQQIPSREAMRMRMRMRCFYFDARPGVILPGETRTFFFLFKSERAGIFSECWEFRTHPLLLGGALLQVTLWGIAVSEDKLADLREKLEADVAAQEGAAIVEETLKDLLVQIRTPERTPSPVDVCITEEELFHRKNPKLHYQHRVVEQLCDLWRQHSTAPPALGEEVPSDQESAVEDVRSQQGVLGALSAQEGSDWKSTLEATPSRVSDVGEEEPGSSSWNFSFEDLQQALKSIPQEEQREAALSQLNEALLELCAEQRPTQSDLLHQTCLQLWREAVDGLVGHSVRLRSQLGLPERDTCVDVGPEGRGEEKQPVEEGDKITGRREEKTSVGGKDKEDKRRTTKTAGKEKEERPNSRKSKVKEKKKLKSGSSSEKEMAQPTGAAAAAPAAPPREQMDPTVWGLYQEKLYVEVYGLLDSMVSKMVSLFEELEQNTVL", "length": 899, "header": "tr|A0A8V1AN43-1|A0A8V1AN43_CHICK Isoform 1 of Radical S-adenosyl methionine domain containing 1 OS=Gallus gallus OX=9031 GN=MYCBPAP PE=4 SV=1 CANONICAL=A0A8V1AN43-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43/entry#A0A8V1ALE0-1", "sequence": { "sequence": "MGGGGIEGIEGSSDPTGSVVLCNAPLRWEAVCAGGTFVGNCAAVVRSLQLRAPRPPRDAGRIPVRRKFLVRKCQPRETRSAGQLLVARPAFPRAAREPLRFSGPALFNGGCGQILPHHVLGSLQELRMEASARGNAQIADFIQAPHQNVAAAVLKEERGGKAKRKFNRTPTSEHKALQNWHRNMAIRRRQETFLGEVLQKPENELLMSISEDYRQIQEERELIDRSLPALFPGKGYRAGSEFWSQPERVGDELTGLTVTLTRRERGCPEPVTHVGKPHTVRMETGVKPPKRSPFHLTWDKSLFLKQRRQELKSILEELDFYQPDLDGLEVIGKGRPFTSVSAQPLPRSAAFEDSETSSDSLEDRCSVVPETVLGPSLDFCGQPACWINCIASCRDEVGIAARLTFETVVGEKAESFLTVSNDGTAAVWYNWRRLLQQIPSREAMRMRMRMRCFYFDARPGVILPGETRTFFFLFKSERAGIFSECWEFRTHPLLLGGALLQVTLWGIAVSEDKLADLREKLEADVAAQEGAAIVEETLKDLLVQIRTPERTPSPVDVCITEEELFHRKNPKLHYQHRVVEQLCDLWRQHSTAPPALGEEVPSDQESAVEDVRSQQGVLGALSAQEGSDWKSTLEATPSRVSDVGEEEPGSSSWNFSFEDLQQALKSIPQEEQREAALSQLNEALLELCAEQRPTQSDLLHQTCLQLWREAVDGLVGHSVRLRSQLGLPERDTCVDVGPEGRGEEKQPVEEGDKITGRREEKTSVGGKDKEDKRRTTKTAGKEKEERPNSRKSKVKEKKKLKSGSSSEKEMAQPTGAAAAAPAAPPREQMDPTVWGLYQEKLYVEVSPAKTCAFISAFCPLLTNRP", "length": 865, "header": "tr|A0A8V1ALE0-1|A0A8V1AN43_CHICK Computationally mapped isoform of Radical S-adenosyl methionine domain containing 1 OS=Gallus gallus OX=9031 GN=MYCBPAP PE=4 SV=1 CANONICAL=A0A8V1AN43-1" }, "locus": { "chromosome": "18", "start_pos": 10969697, "end_pos": 10960556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071675.1", "url": "https://www.ensembl.org/id/ENSGALT00010071675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044365.1", "url": "https://www.ensembl.org/id/ENSGALP00010044365.1" } ] } }, { "isoform_ac": "A0A8V1AN43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43/entry#A0A8V1AN43-1", "sequence": { "sequence": "MGGGGIEGIEGSSDPTGSVVLCNAPLRWEAVCAGGTFVGNCAAVVRSLQLRAPRPPRDAGRIPVRRKFLVRKCQPRETRSAGQLLVARPAFPRAAREPLRFSGRVELQGLPLASGCGRTGLSGLPCRLVVFVGPALFNGGCGQILPHHVLGSLQELRMEASARGNAQIADFIQAPHQNVAAAVLKEERGGKAKRKFNRTPTSEHKALQNWHRNMAIRRRQETFLGEVLQKPENELLMSISEDYRQIQEERELIDRSLPALFPGKGYRAGSEFWSQPERVGDELTGLTVTLTRRERGCPEPVTHVGKPHTVRMETGVKPPKRSPFHLTWDKSLFLKQRRQELKSILEELDFYQPDLDGLEVIGKGRPFTSVSAQPLPRSAAFEDSETSSDSLEDRCSVVPETVLGPSLDFCGQPACWINCIASCRDEVGIAARLTFETVVGEKAESFLTVSNDGTAAVWYNWRRLLQQIPSREAMRMRMRMRCFYFDARPGVILPGETRTFFFLFKSERAGIFSECWEFRTHPLLLGGALLQVTLWGIAVSEDKLADLREKLEADVAAQEGAAIVEETLKDLLVQIRTPERTPSPVDVCITEEELFHRKNPKLHYQHRVVEQLCDLWRQHSTAPPALGEEVPSDQESAVEDVRSQQGVLGALSAQEGSDWKSTLEATPSRVSDVGEEEPGSSSWNFSFEDLQQALKSIPQEEQREAALSQLNEALLELCAEQRPTQSDLLHQTCLQLWREAVDGLVGHSVRLRSQLGLPERDTCVDVGPEGRGEEKQPVEEGDKITGRREEKTSVGGKDKEDKRRTTKTAGKEKEERPNSRKSKVKEKKKLKSGSSSEKEMAQPTGAAAAAPAAPPREQMDPTVWGLYQEKLYVEVYGLLDSMVSKMVSLFEELEQNTVL", "length": 899, "header": "tr|A0A8V1AN43-1|A0A8V1AN43_CHICK Isoform 1 of Radical S-adenosyl methionine domain containing 1 OS=Gallus gallus OX=9031 GN=MYCBPAP PE=4 SV=1 CANONICAL=A0A8V1AN43-1" }, "locus": { "chromosome": "18", "start_pos": 10969697, "end_pos": 10960067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071674.1", "url": "https://www.ensembl.org/id/ENSGALT00010071674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044364.1", "url": "https://www.ensembl.org/id/ENSGALP00010044364.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 666, "start_aa": "Thr", "end_pos": 666, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr666", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN43", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" } ], 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALE1-1", "uniprot_ac": "A0A8V1ALE1", "uniprot_id": "A0A8V1ALE1_CHICK", "mass": { "chemical_mass": 35864.0, "monoisotopic_mass": 35864.0 }, "refseq": { "ac": "XP_015154127", "name": "circadian-associated transcriptional repressor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154127" }, "gene_names": [ { "name": "CIART", "type": "recommended", "evidence": [ { "id": "A0A8V1ALE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE1" } ] }, { "name": "CIART", "type": "synonym", "evidence": [ { "id": "XP_015154127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154127" } ] } ], "protein_names": [ { "name": "Circadian associated repressor of transcription", "type": "synonym", "evidence": [ { "id": "A0A8V1ALE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE1/entry#names_and_taxonomy" } ] }, { "name": "circadian-associated transcriptional repressor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015154127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154127" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052556.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015154127.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015154127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154127" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CIART", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE1", "locus": {} } ], "crossref": [ { "id": "A0A8V1ALE1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055142", "url": "https://www.ncbi.nlm.nih.gov/gene/107055142", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107055142", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055142", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ALE1", "url": "https://www.orthodb.org/?gene=A0A8V1ALE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35441:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35441:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15673", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15673", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015154127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015154127", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": 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"MEGRGHGPTLPTNRLGAASALGTACGGTSQSGIRGVAERGGSAHYQGCDGQWERRGRGDGGGTCGRARVRVGQPQPGRNRRRCRDSATGSGTGTEGRGERHRAGTAPPQRPPPAGDSDPMEPSRRSPRSGDGIGTETPPRAPPGPPRCERGRKRRAGGDPELPPVPRGAKRPKDGDGGPRHSSPPPSDGDRLFAQKCRELRGFIRPLTELLNGLRMGRYDKGLSSFQQSVAMDRIQRIIGVLQKPEMGARYLGTLLQVEVMLKVWFPHVAPKAGPEPDPVGVLLLLRDRRSAHGDGATSGTSGGTSGTASGVTAETTPTGTTQPKCPLPTRTGAPTPPAAPDV", "length": 343, "header": "tr|A0A8V1ALE1-1|A0A8V1ALE1_CHICK Isoform 1 of Circadian associated repressor of transcription OS=Gallus gallus OX=9031 GN=CIART PE=4 SV=1 CANONICAL=A0A8V1ALE1-1" }, "locus": { "chromosome": "25", "start_pos": 2310807, "end_pos": 2308686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069296.1", "url": "https://www.ensembl.org/id/ENSGALT00010069296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042738.1", "url": "https://www.ensembl.org/id/ENSGALP00010042738.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { 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"https://www.uniprot.org/uniprotkb/A0A8V1ALE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE1" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 336 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALE9-1", "uniprot_ac": "A0A8V1ALE9", "uniprot_id": "A0A8V1ALE9_CHICK", "mass": { "chemical_mass": 38068.0, "monoisotopic_mass": 38068.0 }, "refseq": { "ac": "NP_001026702", "name": "ankyrin repeat domain-containing protein 40", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026702" }, "gene_names": [ { "name": "ANKRD40", "type": "recommended", "evidence": [ { "id": "A0A8V1ALE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE9" } ] }, { "name": "ANKRD40", "type": "synonym", "evidence": [ { "id": "NP_001026702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026702" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 40", "type": "synonym", "evidence": [ { "id": "A0A8V1ALE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE9/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 40", "type": "synonym", "evidence": [ { "id": "NP_001026702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026702" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720204.1, SRR13267656.8682.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000317.1. On Oct 25, 2021 this sequence version replaced NP_001026702.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026702", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026702" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE9", "locus": { "chromosome": "18", "start_pos": 10772621, "end_pos": 10765942, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029287", "url": "https://www.ensembl.org/id/ENSGALG00010029287" } ] } } ], "crossref": [ { "id": "A0A8V1ALE9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALE9", "database": "AlphaFoldDB", "categories": [] }, { "id": "428678", "url": "https://www.ncbi.nlm.nih.gov/gene/428678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428678", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYTEDTQ", "url": "https://omabrowser.org/oma/group/DYTEDTQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALE9", "url": "https://www.orthodb.org/?gene=A0A8V1ALE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24192:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24192:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27687", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27687", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001026702", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAKELQERLREAAALGDAEEVRRLLALGVSPNAQNEVNGWTCLHWACKRNHAAVVAQLLLGGADKEILSRKGERPAQLTSRREIRRMLGVEEDELPDVTSSSELPIIPNYLANPPFPYVYNSMSSSLPEPPVNGSASHGERQSSASSLLPAAELCVRASARCEDAAPTAGDGALPAVPGGCAGLRCSGAAAQSALFQASWGRAPPSPAGPQQPGAPLGSGSCTGPVPTFQPVFFTGAFPLNMQELVLKVRIQNPSLKENDFIEIELDRQELTYKELLRVSCRELGVNPEHVQKIRKLPNTILRKDKDVARLQDFQELELVLTVSDKHFPFRAPALSEQSGYNKKASELTY", "length": 351, "header": "tr|A0A8V1ALE9-1|A0A8V1ALE9_CHICK Isoform 1 of Ankyrin repeat domain 40 OS=Gallus gallus OX=9031 GN=ANKRD40 PE=1 SV=1 CANONICAL=A0A8V1ALE9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALE9/entry#A0A8V1ALE9-1", "sequence": { "sequence": "MEAKELQERLREAAALGDAEEVRRLLALGVSPNAQNEVNGWTCLHWACKRNHAAVVAQLLLGGADKEILSRKGERPAQLTSRREIRRMLGVEEDELPDVTSSSELPIIPNYLANPPFPYVYNSMSSSLPEPPVNGSASHGERQSSASSLLPAAELCVRASARCEDAAPTAGDGALPAVPGGCAGLRCSGAAAQSALFQASWGRAPPSPAGPQQPGAPLGSGSCTGPVPTFQPVFFTGAFPLNMQELVLKVRIQNPSLKENDFIEIELDRQELTYKELLRVSCRELGVNPEHVQKIRKLPNTILRKDKDVARLQDFQELELVLTVSDKHFPFRAPALSEQSGYNKKASELTY", "length": 351, "header": "tr|A0A8V1ALE9-1|A0A8V1ALE9_CHICK Isoform 1 of Ankyrin repeat domain 40 OS=Gallus gallus OX=9031 GN=ANKRD40 PE=1 SV=1 CANONICAL=A0A8V1ALE9-1" }, "locus": { "chromosome": "18", "start_pos": 10770729, "end_pos": 10766000, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070831.1", "url": "https://www.ensembl.org/id/ENSGALT00010070831.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043522.1", "url": "https://www.ensembl.org/id/ENSGALP00010043522.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 169, "start_aa": "Thr", "end_pos": 169, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428678", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428678", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A058-1", "protein_name": "Ankyrin repeat domain 40", "gene_name": "ANKRD40", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLRSGADKEILTTKGEMPVQLTSRREIRKIMGVEDDDDDSDNLPQLKKESELPFVPNYLANPAFPFIYTPAAEDSAQLQNGGPSTPPASPPVDGSPPLLPTGEPPLLGAFPRDHTSLALVQNGDVSAPSAILRTPESTKPGPVCQPPVSQSRSLFSSVPSKPPVSLEPQNGAYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVSCCELGVNPDQVEKIRKLPNTLVRKDKDVARLQDFQELELVLMISENNFLFRNAASTLTDRPCYNRRASKLTY", "length": 365 }, "evidence": [ { "id": "A0A8V1ALE9", "url": "https://omabrowser.org/oma/group/A0A8V1ALE9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B2RYI5-1", "protein_name": "Ankyrin repeat domain 40", "gene_name": "Ankrd40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLQSGADREILTTKGEMPVQLTSRREIRKIMGVEEADDDEEIPQLKKESELPFVPNYLANPAFPFIYTPAAEDATQLQNGGPSPPPVSPPAEGSPPLLPPTEPPLLGAFPRDHTSLALVQNGDISAPSAILRTPESTKPGPVCQPPVSQNRSLFSVPSKPPVSLEPQNGTYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVSCCELGVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLTISENNFLFRNPASSLTERPCFNRRASKLTY", "length": 363 }, "evidence": [ { "id": "A0A8V1ALE9", "url": "https://omabrowser.org/oma/group/A0A8V1ALE9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FE71-1", "protein_name": "Ankyrin repeat domain-containing protein 40", "gene_name": "ankrd40", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTTSLDKELQERLREASAIGDIDEVKTLVESGVNVNSQNEINGWTCLHWACKRNHKQIVAYLLNNGADKDILTAKEELAVQLTSKPEIRRLLGVEEEDEPEVKEPELPIIPNYLSNPPFLYSKMNKDNLSIAQQNGTNSTHAEPLESEPATLSPTQEQQLPAPSHQQPKSLYTDSQSQQELTFVPGVEQNGVVPSPVVNGGLPMELSSETHHTNHCEFTHAHPIAQNGPVCPSASTSQPPQLPGTTISRQQSIQPQINCSQISGSMPAFQPFFFTSTFPVNVQELVLKVRIQNTNIRENDFIEVELDRQELTYRALLRVCCRELDISAEHVEKIRKLPNTMLRKDKDVARLQDFQELEVVLEKTEGLSLFSAQGGLTDRPCYNMKASRLTY", "length": 392 }, "evidence": [ { "id": "A0A8V1ALE9", "url": "https://omabrowser.org/oma/group/A0A8V1ALE9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5SUE8-1", "protein_name": "Ankyrin repeat domain-containing protein 40", "gene_name": "Ankrd40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLQSGADREILTTKGEMPVQLTSRREIRKIMGVEEADEEEEIPQLKKESELPFVPNYLANPAFPFIYTPAAEDSTQLQNGGPSPPPVSPPADSSPPLLPPTETPLLGAFPRDHSSLALVQNGDISAPSAILRTPESTKPGPVCQPPVSQNRSLFSVPSKPPVSLEPQNGTYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVSCCELGVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISDNNFLFRNAASTLTERPCYNRRASKLTY", "length": 363 }, "evidence": [ { "id": "A0A8V1ALE9", "url": "https://omabrowser.org/oma/group/A0A8V1ALE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AI12-1", "protein_name": "Ankyrin repeat domain-containing protein 40", "gene_name": "ANKRD40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLKSGADKEILTTKGEMPVQLTSRREIRKIMGVEEEDDDDDDDDNLPQLKKESELPFVPNYLANPAFPFIYTPTAEDSAQMQNGGPSTPPASPPADGSPPLLPPGEPPLLGTFPRDHTSLALVQNGDVSAPSAILRTPESTKPGPVCQPPVSQSRSLFSSVPSKPPMSLEPQNGTYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVCCCELGVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISENNFLFRNAASTLTERPCYNRRASKLTY", "length": 368 }, "evidence": [ { "id": "A0A8V1ALE9", "url": "https://omabrowser.org/oma/group/A0A8V1ALE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 169 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AN15-1", "uniprot_ac": "A0A8V1AN15", "uniprot_id": "A0A8V1AN15_CHICK", "mass": { "chemical_mass": 51823.0, "monoisotopic_mass": 51823.0 }, "refseq": { "ac": "XP_015151699", "name": "F-box only protein 39 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151699" }, "gene_names": [ { "name": "FBXO39", "type": "recommended", "evidence": [ { "id": "A0A8V1AN15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15" } ] }, { "name": "FBXO39", "type": "synonym", "evidence": [ { "id": "XP_015151699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151699" } ] } ], "protein_names": [ { "name": "F-box only protein 39", "type": "recommended", "evidence": [ { "id": "A0A8V1AN15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15/entry#names_and_taxonomy" } ] }, { "name": "F-box only protein 39 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015151699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151699" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151699" } ] }, { "annotation": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PK65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK65#function" }, { "database": "UniProtKB", "id": "ARBA00003437", "url": "https://www.uniprot.org/uniprotkb/ARBA00003437#function" }, { "database": "UniProtKB", "id": "A0A8V1ALG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG2#function" }, { "database": "UniProtKB", "id": "A0A8V1AN15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15#function" }, { "database": "UniProtKB", "id": "A0A8V1AC09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC09#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15", "locus": { "chromosome": "19", "start_pos": 10388126, "end_pos": 10376594, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029296", "url": "https://www.ensembl.org/id/ENSGALG00010029296" } ] } } ], "crossref": [ { "id": "A0A8V1AN15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AN15", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029322", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22108", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22108", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "776097", "url": "https://www.ncbi.nlm.nih.gov/gene/776097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776097", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PK65", "url": "https://www.orthodb.org/?gene=A0A1D5PK65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AC09", "url": "https://www.orthodb.org/?gene=A0A8V1AC09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALG2", "url": "https://www.orthodb.org/?gene=A0A8V1ALG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN15", "url": "https://www.orthodb.org/?gene=A0A8V1AN15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20933", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20933", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20933:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20933:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151699", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151699", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PK65", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PK65-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PK65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC09", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AC09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDDSDLEQSSWANLPDVCLRHVFHWLDDKDRSRAAMVCKKWNQAMYSGSLWRTRTITFNGQPSRAHAFEFETALWYVKKFGKYLEHLEIKLLHPYSTVFTRKFQVSMRGLLSHLGKCNCRLVSLSIKHLELDRLVWKNVVRAQFIKNLGTFLKRMSKQLNYLNLKGARVTLEEGCELLNSLSCLTNKSFISEINIEDFFSLHLPVYSSTLFHHTVSKFHSLAVLTFNYNCISDELLDILCKNSAHSLCTLNIKCHIHDPHGQVVWGMSWANLAKRAPKLNVNFYFERVMKHDHLARILLVEIPVRSISLRSCYFRDPYWMMRPTLTNILPAYWHVLQKLTLEVNNDNELLDDELLQLILSCRKLFFLKVWAFLSVTFMERLLHNRAERKCFLTTIKVRIYTSRQETSEEERLLHNIYKKFKNLIDSELNYFVITYPLV", "length": 439, "header": "tr|A0A8V1AN15-1|A0A8V1AN15_CHICK Isoform 1 of F-box only protein 39 OS=Gallus gallus OX=9031 GN=FBXO39 PE=4 SV=1 CANONICAL=A0A8V1AN15-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PK65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15/entry#A0A1D5PK65-1", "sequence": { "sequence": "MEDDSDLEQSSWANLPDVCLRHVFHWLDDKDRSRAAMVCKKWNQAMYSGSLWRTRTITFNGQPSRAHAFEFETALWYVKKFGKYLEHLEIKLLHPYSTVFTRKFQVSMRGLLSHLGKCNCRLVSLSIKHLELDRLVWKNVVRAQFIKNLGTFLKRMSKQLNYLNLKGARVTLEEGCELLNSLSCLTNKSFISEINIEDFFSLHLPVYSSTLFHHTVSKFHSLAVLTFNYNCISDELLDILCKNSAHSLCTLNIKCHIHDPHGQVVWGMSWANLAKRAPKLNVNFYFERVMKHDHLARILLVEIPVRSISLRSCYFRDPYWMMRPTLTNILPAYWHVLQKLTLEVNNDNELLDDELLQLILSCRKLFFLKVWAFLSVTFMERLLHNRAERKCFLTTIKNQKQQ", "length": 402, "header": "tr|A0A1D5PK65-1|A0A1D5PK65_CHICK Computationally mapped isoform of F-box only protein 39 OS=Gallus gallus OX=9031 GN=FBXO39 PE=4 SV=2 CANONICAL=A0A8V1AN15-1" }, "locus": { "chromosome": "19", "start_pos": 10383230, "end_pos": 10380089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070848.1", "url": "https://www.ensembl.org/id/ENSGALT00010070848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043539.1", "url": "https://www.ensembl.org/id/ENSGALP00010043539.1" } ] } }, { "isoform_ac": "A0A8V1AC09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15/entry#A0A8V1AC09-1", "sequence": { "sequence": "MEDDSDLEQSSWANLPDVCLRHVFHWLDDKDRSRAAMVCKKWNQAMYSGSLWRTRTITFNGQPSRAHAFEFETALWYVKKFGKYLEHLEIKLLHPYSTVFTRKFQVSMRGLLSHLGKCNCRLVSLSIKHLELDRLVWKNVVRAQFIKNLGTFLKRMSKQLNYLNLKGARVTLEEGCELLNSLSCLTNKSFISEINIEDFFSLHLPVYSSTLFHHTVSKFHSLAVLTFNYNCISDELLDILCKNSAHSLCTLNIKCHIHDPHGQVVWGMSWANLAKRAPKLNVNFYFERVMKHDHLARILLVEIPVRSISLRSCYFRDPYWMMRPTLTNILPAYWHVLQKLTLEVNNDNELLDDELLQLILSCRKLFFLKVWAFLSVTFMERLLHNRAERKCFLTTIKSSTLSY", "length": 403, "header": "tr|A0A8V1AC09-1|A0A8V1AC09_CHICK Computationally mapped isoform of F-box only protein 39 OS=Gallus gallus OX=9031 GN=FBXO39 PE=4 SV=1 CANONICAL=A0A8V1AN15-1" }, "locus": { "chromosome": "19", "start_pos": 10387781, "end_pos": 10380089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070849.1", "url": "https://www.ensembl.org/id/ENSGALT00010070849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043540.1", "url": "https://www.ensembl.org/id/ENSGALP00010043540.1" } ] } }, { "isoform_ac": "A0A8V1ALG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15/entry#A0A8V1ALG2-1", "sequence": { "sequence": "MEDDSDLEQSSWANLPDVCLRHVFHWLDDKDRSRAAMVCKKWNQAMYSGSLWRTRTITFNGQPSRAHAFEFETALWYVKKFGKYLEHLEIKLLHPYSTVFTRKFQVSMRGLLSHLGKCNCRLVSLSIKHLELDRLVWKNVVRAQFIKNLGTFLKRMSKQLNYLNLKGARVTLEEGCELLNSLSCLTNKSFISEINIEDFFSLHLPVYSSTLFHHTVSKFHSLAVLTFNYNCISDELLDILCKNSAHSLCTLNIKCHIHDPHGQVVWGMSWANLAKRAPKLNVNFYFERVMKHDHLARILLVEIPVRSISLRSCYFRDPYWMMRPTLTNILPAYWHVLQKLTLEVNNDNELLDDELLQLILSCRKLFFLKVWAFLSVTFMERLLHNRAERKCFLTTIKVRLCASKLPLSTFLSSISREMLRSP", "length": 422, "header": "tr|A0A8V1ALG2-1|A0A8V1AN15_CHICK Computationally mapped isoform of F-box only protein 39 OS=Gallus gallus OX=9031 GN=FBXO39 PE=4 SV=1 CANONICAL=A0A8V1AN15-1" }, "locus": { "chromosome": "19", "start_pos": 10382183, "end_pos": 10380089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070847.1", "url": "https://www.ensembl.org/id/ENSGALT00010070847.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043538.1", "url": "https://www.ensembl.org/id/ENSGALP00010043538.1" } ] } }, { "isoform_ac": "A0A8V1AN15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15/entry#A0A8V1AN15-1", "sequence": { "sequence": "MEDDSDLEQSSWANLPDVCLRHVFHWLDDKDRSRAAMVCKKWNQAMYSGSLWRTRTITFNGQPSRAHAFEFETALWYVKKFGKYLEHLEIKLLHPYSTVFTRKFQVSMRGLLSHLGKCNCRLVSLSIKHLELDRLVWKNVVRAQFIKNLGTFLKRMSKQLNYLNLKGARVTLEEGCELLNSLSCLTNKSFISEINIEDFFSLHLPVYSSTLFHHTVSKFHSLAVLTFNYNCISDELLDILCKNSAHSLCTLNIKCHIHDPHGQVVWGMSWANLAKRAPKLNVNFYFERVMKHDHLARILLVEIPVRSISLRSCYFRDPYWMMRPTLTNILPAYWHVLQKLTLEVNNDNELLDDELLQLILSCRKLFFLKVWAFLSVTFMERLLHNRAERKCFLTTIKVRIYTSRQETSEEERLLHNIYKKFKNLIDSELNYFVITYPLV", "length": 439, "header": "tr|A0A8V1AN15-1|A0A8V1AN15_CHICK Isoform 1 of F-box only protein 39 OS=Gallus gallus OX=9031 GN=FBXO39 PE=4 SV=1 CANONICAL=A0A8V1AN15-1" }, "locus": { "chromosome": "19", "start_pos": 10383003, "end_pos": 10380089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070850.1", "url": "https://www.ensembl.org/id/ENSGALT00010070850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043541.1", "url": "https://www.ensembl.org/id/ENSGALP00010043541.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:776097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776097", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN15", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AN15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN15" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 55, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALH1-1", "uniprot_ac": "A0A8V1ALH1", "uniprot_id": "A0A8V1ALH1_CHICK", "mass": { "chemical_mass": 24775.0, "monoisotopic_mass": 24775.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ALH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH1", "locus": {} } ], "crossref": [ { "id": "A0A8V1ALH1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALH1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALJ0-1", "uniprot_ac": "A0A8V1ALJ0", "uniprot_id": "A0A8V1ALJ0_CHICK", "mass": { "chemical_mass": 21259.0, "monoisotopic_mass": 21259.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ALJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ0", "locus": {} } ], "crossref": [ { "id": "A0A8V1ALJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24156", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24156", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24156:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24156:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ALJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPTEGPTVAAEGPTVPAEGPALQGGAYINEGDARGRTALMAACRARYADPGERARMVRYLLRCGADPNIADAAGMTALMHACAERAGAAVAALLLEHGADPGARDYGGSSALLYAAQRGDRPTLQALLDACEARGREVIIITTATSPSGTKTTRQYLHAAPPSPTPQDPKVNPTETPWRTHRDTMGLQSDTAGYQSITMGTSQ", "length": 204, "header": "tr|A0A8V1ALJ0-1|A0A8V1ALJ0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1ALJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ0/entry#A0A8V1ALJ0-1", "sequence": { "sequence": "MVPTEGPTVAAEGPTVPAEGPALQGGAYINEGDARGRTALMAACRARYADPGERARMVRYLLRCGADPNIADAAGMTALMHACAERAGAAVAALLLEHGADPGARDYGGSSALLYAAQRGDRPTLQALLDACEARGREVIIITTATSPSGTKTTRQYLHAAPPSPTPQDPKVNPTETPWRTHRDTMGLQSDTAGYQSITMGTSQ", "length": 204, "header": "tr|A0A8V1ALJ0-1|A0A8V1ALJ0_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V1ALJ0-1" }, "locus": { "chromosome": "25", "start_pos": 800637, "end_pos": 798889, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069537.1", "url": "https://www.ensembl.org/id/ENSGALT00010069537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042798.1", "url": "https://www.ensembl.org/id/ENSGALP00010042798.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 166, "start_aa": "Thr", "end_pos": 166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr166", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 8, "start_aa": "Thr", "end_pos": 8, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr8", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 8, 15, 166 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALJ9-1", "uniprot_ac": "A0A8V1ALJ9", "uniprot_id": "A0A8V1ALJ9_CHICK", "mass": { "chemical_mass": 110807.0, "monoisotopic_mass": 110807.0 }, "refseq": { "ac": "XP_024997485", "name": "coiled-coil domain-containing protein 40", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997485" }, "gene_names": [ { "name": "CCDC40", "type": "recommended", "evidence": [ { "id": "A0A8V1ALJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ] }, { "name": "CCDC40", "type": "synonym", "evidence": [ { "id": "XP_024997485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997485" } ] } ], "protein_names": [ { "name": "Coiled-coil domain 40 molecular ruler complex subunit", "type": "synonym", "evidence": [ { "id": "A0A8V1ALJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 40", "type": "synonym", "evidence": [ { "id": "XP_024997485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997485" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997485.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997485" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9", "locus": { "chromosome": "18", "start_pos": 10186798, "end_pos": 10198162, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029313", "url": "https://www.ensembl.org/id/ENSGALG00010029313" } ] } } ], "crossref": [ { "id": "A0A8V1ALJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "422083", "url": "https://www.ncbi.nlm.nih.gov/gene/422083", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422083", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422083", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMQRIQK", "url": "https://omabrowser.org/oma/group/RMQRIQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALJ9", "url": "https://www.orthodb.org/?gene=A0A8V1ALJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16275", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16275", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16275:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16275:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_024997485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFDGSPPDLTEMEQPGTESENPPHMASGAPVQAPAFPGELNSSTEPESALEQSRQLASEHGGQKWQQERQQLGAEQNEASGRSNEAAEETQLVVLDPEHPLMRRFQTALKNYLTKQMEKVDLELRELRTATKKSKEQREELGVILYGVQQQLAHLQLELEKSHDRRSQAATARRQLEEELEGLRLTYQKACQNTDDERRKVSAMQTQAENLASRLLYMQNMDEEMHHNILLMKQSTKKAEAEKVQAEVEKKKQDLLVERLTRKAYELQEQIALFEAQFVAQAEDTKVTRQAVNEACMEVQAINMEKKRLMNHWTNSLAGVKQRDEAYIAAQELLSKYRHDLKSIETNIHGYRKSIRKEEEKNEMLVTILNRSCNDANTTKKLIAQCLSKQEALKLESGTYTHVLEETQQAISRIKMDQAARLNELLSISKDIEKGTEAKEQMESEIMAKLQDQMMSNKAEKHFSQLVAKLHQRKTDLELHFSKVENDMSQVILNTTHTNCRLTALQKTLCELDKEIKTIHDLIRHSESEISKYNLLIENKQGLIRQYNQKLEVLLSQQGGQELGPLEIEINKLTKEIEECNSEVMTLQKYWLSLQRELLKLTREQEDQLTSLDMLKKQMTIMQQKKVRTENDIQQEIKEQKDLERRMKSISNDLIKLNVLINKNNSSFTELQYGNIITENEFVRSLKAAEKESIEMQEKHSQLTEEKERLLNSLVEAEHQIMLWEKKIQLTKEMRSAVDSERGQGEIRAMRAEIHRMQVRYSQLMKQQEKMIRDMEASVSRREAIAIRGEGQNKTDKKRITKSDFCRKKEELRKKIAETQKNAQDCNKIILELESSQASLSASLLEKQQAMCMLQTESHGLDSHTECLRYKKRWNLLEIVAYQTRQKHLQALKEGKYTPLCSSEQACRNEQQKLQERLRAVSAIVHRVQQEQPQHRPALQWLGECLESGLGSQEA", "length": 956, "header": "tr|A0A8V1ALJ9-1|A0A8V1ALJ9_CHICK Isoform 1 of Coiled-coil domain 40 molecular ruler complex subunit OS=Gallus gallus OX=9031 GN=CCDC40 PE=4 SV=1 CANONICAL=A0A8V1ALJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9/entry#A0A8V1ALJ9-1", "sequence": { "sequence": "MEFDGSPPDLTEMEQPGTESENPPHMASGAPVQAPAFPGELNSSTEPESALEQSRQLASEHGGQKWQQERQQLGAEQNEASGRSNEAAEETQLVVLDPEHPLMRRFQTALKNYLTKQMEKVDLELRELRTATKKSKEQREELGVILYGVQQQLAHLQLELEKSHDRRSQAATARRQLEEELEGLRLTYQKACQNTDDERRKVSAMQTQAENLASRLLYMQNMDEEMHHNILLMKQSTKKAEAEKVQAEVEKKKQDLLVERLTRKAYELQEQIALFEAQFVAQAEDTKVTRQAVNEACMEVQAINMEKKRLMNHWTNSLAGVKQRDEAYIAAQELLSKYRHDLKSIETNIHGYRKSIRKEEEKNEMLVTILNRSCNDANTTKKLIAQCLSKQEALKLESGTYTHVLEETQQAISRIKMDQAARLNELLSISKDIEKGTEAKEQMESEIMAKLQDQMMSNKAEKHFSQLVAKLHQRKTDLELHFSKVENDMSQVILNTTHTNCRLTALQKTLCELDKEIKTIHDLIRHSESEISKYNLLIENKQGLIRQYNQKLEVLLSQQGGQELGPLEIEINKLTKEIEECNSEVMTLQKYWLSLQRELLKLTREQEDQLTSLDMLKKQMTIMQQKKVRTENDIQQEIKEQKDLERRMKSISNDLIKLNVLINKNNSSFTELQYGNIITENEFVRSLKAAEKESIEMQEKHSQLTEEKERLLNSLVEAEHQIMLWEKKIQLTKEMRSAVDSERGQGEIRAMRAEIHRMQVRYSQLMKQQEKMIRDMEASVSRREAIAIRGEGQNKTDKKRITKSDFCRKKEELRKKIAETQKNAQDCNKIILELESSQASLSASLLEKQQAMCMLQTESHGLDSHTECLRYKKRWNLLEIVAYQTRQKHLQALKEGKYTPLCSSEQACRNEQQKLQERLRAVSAIVHRVQQEQPQHRPALQWLGECLESGLGSQEA", "length": 956, "header": "tr|A0A8V1ALJ9-1|A0A8V1ALJ9_CHICK Isoform 1 of Coiled-coil domain 40 molecular ruler complex subunit OS=Gallus gallus OX=9031 GN=CCDC40 PE=4 SV=1 CANONICAL=A0A8V1ALJ9-1" }, "locus": { "chromosome": "18", "start_pos": 10197316, "end_pos": 10186893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070893.1", "url": "https://www.ensembl.org/id/ENSGALT00010070893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043584.1", "url": "https://www.ensembl.org/id/ENSGALP00010043584.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422083", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422083", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ANF0-1", "protein_name": "Coiled-coil domain 40 molecular ruler complex subunit", "gene_name": "Ccdc40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPEDQADGSNLEGEQTSAEEETEQQYTEGHEVSPQLENSGQKTAEGREPTQDPERGITTDSEGRLEGEMVDAERVSTEGEAISEGEVGSIGEAFPETEVEFIGEAPPDTVVEFIGEAPPGTEVEFIGETTPETQAEPTGEATPGVAVKTIRKAEQEVEVIREVISETDVDSIVKAIQGVDLESIGATIPQKKVKYTAKARPQDEAEPTGEPAPEGDFDVSEQEKAGHPSELDELSDIISSPAFSYSDVSPWDMGEEEAKALTTQDISQESVYEPIELIQPTEPTEPPEDSVVRPIEPSRQRSFPMGARHRFRLSIMGSLTPSDIDDLPLETEEALQQESVQPPPRAHEETRIQFLDQVQTLSLEDETQIERPMSEGSDEAEEEGAQLMVLDPDHPLMVRFQEALKSYLNRQIDKLKLDIQELDVATKQTRIQRQELGVNLYGVQQHLARLQMQLEKSHDRHSLVACERRRKEEELQCNRALYNKTYATAKEERKKFAALQTEMESLALHLFYMQNIDQDVRDDIQVMKQVVKKTETEKMNAEIEKKKQDLFVDQLTERAHQLEENIALYEAQYLSQAEDTRVLRKAVTEAITEIDTIIMEKKRILQQWTTSLVGMKHRNEAYRTVMDALRECEHQVKSIDSEIEAYKKSIMQEEEKNEKLARLLNRAETEAALVQKMTTQCLSKQETLQTEFNTYQLALQDTEEMLNKGYVEHSAVLSELQGTRQAVHQEQELRQKMDISIMDKLQEHGTSSKMTKYFHQLLRKLQKENTNLVTHLSKIDGDIAQATLDITNTNGKVEMHKKTLLDLDKEVKRFNELITNSESEIVRRTILIERKQSLINFFNKQLEQMVSVLGGEEAGPLELEIKRLSKLTEEYNTGVTQAQMTWLRLQQELVQISHEREERLESVDQLKKEVHIMEQKKLRIENKIEHEKREQKMVSRHMRDLDNDLSKLNMLLDKNRCSSELLEQNNAVAETEFVRTLKDAERETIQMQEKLSELCEEKATLLNSLVEAEHQIMLWEKKIQLAKEMRSSVDSDTGQTEIRAMKAEIHRMRVKHGQLLKQQEKMIRDMELAVARRETIVIQAEGQSKIDKKIVTKSDFHFQQSELRKKIREVHKATEECSKTVLELEEAQKLLSSSLQEKQQSLSDMQSDTDVLEEEISHLSALKRKNLLEIVALQTRAKHLQAAVDGKYVFLHRNSKAQLMERKRLGMKLSQLSSVLSRVQEDYPQYQEMLQKIQEKIATRLEAPEPS", "length": 1253 }, "evidence": [ { "id": "A0A8V1ALJ9", "url": "https://omabrowser.org/oma/group/A0A8V1ALJ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAJ3-1", "protein_name": "Coiled-coil domain 40 molecular ruler complex subunit", "gene_name": "CCDC40", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEPDGGAGGSHLGGKSPSEGEEDQHVEGGKVSSMEKSNDQRSEEAEGATEHSEREIENDGEVTAQGDYGGSQGEMEMEEEFELEEELESDLEATSPEGEVSSLDLASSDISRGEGPEDEVDRTPPYEGTRREMGLEDREAPHPSKSTGMGFITTKSSQQVLGLSEQMNQGTLQQKVFPLEAGHHLRQSPGSSDTSLGLDELPPGTEEPFAPESEPDTHPREGATSSFLDRIQQLSMVEEGGLVETVESEGSDEAEEDRSQLVVLDPDHPLMIRFQAALKSYLNRQIEKLRLELQELSVATKQSRVQRQELGVNLYGVQQHLARLQMQLEKSHDRHSIAACTRRQKEEELQRVRLLYAKTCETANEERKKLAALQTEMETLALHLFYMQNIDQDVRDDIQVMKQVVKKSEAQRMRAELEKKQQDLHVDQLTTRANQLEEQTALFEAQYHAQAKDTQMLRKAVSEACTEIEAISMEKKHILQQWATSLVGMKHRDEAHRTIQEALSECQHQVKSMDVELEAYKKSIMKEEEKNEKLASILNRAETEANLMQKLTSQCLTKEEALQNEFNTYRLTLLDTEDALGKAHVEYTATVGELQTLHQAIQHEQELRRKMDASIMEKLKEHMTSNKMTKYFHQLILKLQKEKTNLVTHLSKIDGDIAQTTLDITNTNCRLDMHQKILAELDKEVKKVNDLINNSENEISRRTILIERKQGLINFFNKQLEQMVSELGGEEVGPLELEIKRLTKLIEENNTNVTQAQVTWLRLQQEMVKVTQEREEHLVSLDMSKKEIHILEQKKIRIENKINQEKKEQKQIERHMKDLDNDLKKLNLLMNQNRCSSEELQQDNLATEGEFVRSLKASERETIEMQEKLNQLSEEKAAVLNSLVEAEHQIMLWEKKIQLAKEMRASVDSETGQMEIRAMKAEIHRMKVKHGQLLKQQEKMIRDMELAVTRRDTISTRAEGQSKMDKKLFTRTDFHHKQTELRRKIRDIHKATEECTQTILELEESQKSMSDSLLEKQEQLSRMQVEADELEVELDRLATLKRQNLSELVALQTRLKYLQAVKDGRYVFMLRNKQSLLMELKRLHDRLVSIGTILHHVKEEYPQFQEALLKVSQSIDKRLELSGS", "length": 1125 }, "evidence": [ { "id": "A0A8V1ALJ9", "url": "https://omabrowser.org/oma/group/A0A8V1ALJ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4G0X9-1", "protein_name": "Coiled-coil domain-containing protein 40", "gene_name": "CCDC40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPGGAAGRSHPEDGSASEGEKEGNNESHMVSPPEKDDGQKGEEAVGSTEHPEEVTTQAEAAIEEGEVETEGEAAVEGEEEAVSYGDAESEEEYYYTETSSPEGQISAADTTYPYFSPPQELPGEEAYDSVSGEAGLQGFQQEATGPPESRERRVTSPEPSHGVLGPSEQMGQVTSGPAVGRLTGSTEEPQGQVLPMGVQHRFRLSHGSDIESSDLEEFVSQEPVIPPGVPDAHPREGDLPVFQDQIQQPSTEEGAMAERVESEGSDEEAEDEGSQLVVLDPDHPLMVRFQAALKNYLNRQIEKLKLDLQELVVATKQSRAQRQELGVNLYEVQQHLVHLQKLLEKSHDRHAMASSERRQKEEELQAARALYTKTCAAANEERKKLAALQTEMENLALHLFYMQNIDQDMRDDIRVMTQVVKKAETERIRAEIEKKKQDLYVDQLTTRAQQLEEDIALFEAQYLAQAEDTRILRKAVSEACTEIDAISVEKRRIMQQWASSLVGMKHRDEAHRAVLEALRGCQHQAKSTDGEIEAYKKSIMKEEEKNEKLASILNRTETEATLLQKLTTQCLTKQVALQSQFNTYRLTLQDTEDALSQDQLEQMILTEELQAIRQAIQGELELRRKTDAAIREKLQEHMTSNKTTKYFNQLILRLQKEKTNMMTHLSKINGDIAQTTLDITHTSSRLDAHQKTLVELDQDVKKVNELITNSQSEISRRTILIERKQGLINFLNKQLERMVSELGGEEVGPLELEIKRLSKLIDEHDGKAVQAQVTWLRLQQEMVKVTQEQEEQLASLDASKKELHIMEQKKLRVESKIEQEKKEQKEIEHHMKDLDNDLKKLNMLMNKNRCSSEELEQNNRVTENEFVRSLKASERETIKMQDKLNQLSEEKATLLNQLVEAEHQIMLWEKKIQLAKEMRSSVDSEIGQTEIRAMKGEIHRMKVRLGQLLKQQEKMIRAMELAVARRETVTTQAEGQRKMDRKALTRTDFHHKQLELRRKIRDVRKATDECTKTVLELEETQRNVSSSLLEKQEKLSVIQADFDTLEADLTRLGALKRQNLSEIVALQTRLKHLQAVKEGRYVFLFRSKQSLVLERQRLDKRLALIATILDRVRDEYPQFQEALHKVSQMIANKLESPGPS", "length": 1142 }, "evidence": [ { "id": "A0A8V1ALJ9", "url": "https://omabrowser.org/oma/group/A0A8V1ALJ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BI79-1", "protein_name": "Coiled-coil domain-containing protein 40", "gene_name": "Ccdc40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDAEKVSTDGEAISEGEVGSNGETPPETEVEFIGETAPDTDVEFIGETSPGTDVEPTGESIQETEVESIGEATPGMDVEPIKKTMTELNVESIGEETSETDVDSIRKALRGIDLESITVAYPPKKAKHRKVRPQAEVESTGRAAPEGELEVSDHEKVEALLDELDELSEIVSSPEVSYSDISPLEMGEDDTNVSATSTDTFQQGIYEPIEPIEPTEPPEPAEPPKPAETPEDSTVRAPAHPYQRDFPMGARHRFRLSIMGSLTPSDTDDLPLETDEPPQQESVQSTPRALEETRIQFLDQVQSLSPEALLDRATEGSDEAEEEGSQLIVLDPDHPLMIRFQEALKGYLNRQMDKLKLDVQELDVATKQTRSQRQELGVNLYGVQQHLARLQMQLEKSHDRHSLVACERRRKEEELQCARSVYNKTCQTANEERKKLAALQTEVESLALHLFYMQNIEQDVRDDIQVMKQVVRKTETEKMHAEVEKKKQDLFVDQLTERSHQLEENIALFEAQYLSQAEDTRVLKKAVTEAITEIDTIAVEKKRILQQWTTSLVGMKHRNEAYKTVMDALRECQHQVKSTDSEIEVCKKSIMQEEEKNEKLARLLNRAETEATLVQKMTAQCLSKQEALQTEFNTYQLALQDTEEMLNKGYVEHSAVLSELQATRQAFHQEQELRQKMDMSMVDKLQEQGTSSKMTKYFHQLLRKLQKENTNLVTHLSKIDGDIAQATLDITNTNCKIDMHKKTLAEMDKEVKRFNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSELGGEEAGPLELEIKRLSKLTEEYNTGVAEAQMTWLRLQQELVQVTHEREEQLVSVDQLKKEVHIMEQKKLRIESKIAHEKKEQKIVSRHMRDLDNDLSKLNMLLDKNRCSSEELEQNNIATETEFLRTLKDSERETIQMQEKLMELSEEKATLLNSFMEAEHQIMLWEKKIQLAKEMRSSVDSETGQTEIRAMKAEIHRMKVRHGQLLKQQEKMIRDMELAVARRETIVVQAEGQSKIDKKVITKTEFHYQQRELQKKVREMHKATDDCTNTISELEETQKFLSSSLQEKQQLLSEMQATTDVLEEEINQLTALKRQNLLEIVTLQTRGKHLQAAIEGKYVFLHRNSRSQLMERKRLSVRLSQLNKVLSSVQEDYPQYQEVLQSIQQKIATKLETPEPS", "length": 1192 }, "evidence": [ { "id": "A0A8V1ALJ9", "url": "https://omabrowser.org/oma/group/A0A8V1ALJ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency", "id": "GO:0003356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "determination of pancreatic left/right asymmetry", "id": "GO:0035469", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035469", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "epithelial cilium movement involved in determination of left/right asymmetry", "id": "GO:0060287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060287", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "determination of digestive tract left/right asymmetry", "id": "GO:0071907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071907", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" }, { "name": "determination of liver left/right asymmetry", "id": "GO:0071910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071910", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 794, "end_pos": 796 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALL2-1", "uniprot_ac": "A0A8V1ALL2", "uniprot_id": "A0A8V1ALL2_CHICK", "mass": { "chemical_mass": 72118.0, "monoisotopic_mass": 72118.0 }, "refseq": {}, "gene_names": [ { "name": "PIAS3", "type": "recommended", "evidence": [ { "id": "A0A8V1ALL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2" } ] } ], "protein_names": [ { "name": "Protein inhibitor of activated STAT 3", "type": "synonym", "evidence": [ { "id": "A0A8V1ALL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIAS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2", "locus": { "chromosome": "25", "start_pos": 837405, "end_pos": 854587, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028748", "url": "https://www.ensembl.org/id/ENSGALG00010028748" } ] } } ], "crossref": [ { "id": "A0A8V1ALL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055114", "url": "https://www.ncbi.nlm.nih.gov/gene/107055114", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038654", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038654", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107055114", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055114", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENTFMFH", "url": "https://omabrowser.org/oma/group/ENTFMFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA31", "url": "https://www.orthodb.org/?gene=A0A8V1AA31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALL2", "url": "https://www.orthodb.org/?gene=A0A8V1ALL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10782:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10782:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3232118", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232118", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4090294", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5696395", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AA31", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGAELEHMVMSFRVSELQVLLAFSGRNRSGRKHELLAKALQLLRSGCSAAVQMKIAELYRRRFPRRALSPSELPVLHGPVGPLPPLPAPCRLPYEPGAGGPLLVLESRREAEGAQLAPPVQPVHPDVKMQRLPFYDVYDELIKPTTLASASSQRFEEAHFTFALTPQQVQQILSSRDAVLGARCDHAVQVQLRFCLCETSCPQEDHFPPNLFVKVNGKLCPLPGYLPPTKNGVEPKRPSRPVNITPLALLSAALPNTIVVNWSAECGRNYSLSVYLVKQLTAVALLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLAVPCRATTCSHLQCFDAALYLQMNEKKPTWMCPVCDRGAPYDRLIIDGLFMEILNSCTDCDEIEFMEDGSWCPMRHRKEKRELCGAADLAPSLYAGSPEAAPPPPPEVEVIDLTLDSSSDEEGPPPRKHCGTPGAAHPTAGPRGALSAAPRPSSVLRCPTAALCSEFPPTIPDFTPSYTAAPELRGLDLLSFLQDDSQDTAGRSGTWGHSPPPKKGLPFIAPTDGADGPIRSAAPHRCRGRLRPTSPPHISAHGLLTVLSMNDSSTKMVSSTWFSLASILGGAQGLCWGLRAAPSPPILPPPGSALPPPASALRPPPILPPPSPGSALRPLPS", "length": 669, "header": "tr|A0A8V1ALL2-1|A0A8V1ALL2_CHICK Isoform 1 of Protein inhibitor of activated STAT 3 OS=Gallus gallus OX=9031 GN=PIAS3 PE=3 SV=1 CANONICAL=A0A8V1ALL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2/entry#A0A8V1AA31-1", "sequence": { "sequence": "MAEGAELEHMVMSFRVSELQVLLAFSGRNRSGRKHELLAKALQLLRSGCSAAVQMKIAELYRRRFPRRALSPSELPVLHGPVGPLPPLPAPCRLPYEPGAGGPLLVLESRREAEGAQLAPPVQPVHPDVKMQRLPFYDVYDELIKPTTLASASSQRFEEAHFTFALTPQQVQQILSSRDAVLGARCDHAVQVQLRFCLCETSCPQEDHFPPNLFVKVNGKLCPLPGYLPPTKNGVEPKRPSRPVNITPLALLSAALPNTIVVNWSAECGRNYSLSVYLVKQLTAVALLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLAVPCRATTCSHLQCFDAALYLQMNEKKPTWMCPVCDRGAPYDRLIIDGLFMEILNSCTDCDEIEFMEDGSWCPMRHRKEKRELCGAADLAPSLYAGSPEAAPPPPPEVEVIDLTLDSSSDEEGPPPRKHCGTPGAAHPTAGPRGALSAAPRPSSVLRCPTAALCSEFPPTIPDFTPSYTAAPELRGLDLLSFLQDDSQRCGRSVITSLRAADPLGRFLPPAGGAALRDGRRVGSAAPPPRRSNVISLD", "length": 584, "header": "tr|A0A8V1AA31-1|A0A8V1AA31_CHICK Computationally mapped isoform of Protein inhibitor of activated STAT 3 OS=Gallus gallus OX=9031 GN=PIAS3 PE=3 SV=1 CANONICAL=A0A8V1ALL2-1" }, "locus": { "chromosome": "25", "start_pos": 854367, "end_pos": 839245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069566.1", "url": "https://www.ensembl.org/id/ENSGALT00010069566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042827.1", "url": "https://www.ensembl.org/id/ENSGALP00010042827.1" } ] } }, { "isoform_ac": "A0A8V1ALL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2/entry#A0A8V1ALL2-1", "sequence": { "sequence": "MAEGAELEHMVMSFRVSELQVLLAFSGRNRSGRKHELLAKALQLLRSGCSAAVQMKIAELYRRRFPRRALSPSELPVLHGPVGPLPPLPAPCRLPYEPGAGGPLLVLESRREAEGAQLAPPVQPVHPDVKMQRLPFYDVYDELIKPTTLASASSQRFEEAHFTFALTPQQVQQILSSRDAVLGARCDHAVQVQLRFCLCETSCPQEDHFPPNLFVKVNGKLCPLPGYLPPTKNGVEPKRPSRPVNITPLALLSAALPNTIVVNWSAECGRNYSLSVYLVKQLTAVALLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLAVPCRATTCSHLQCFDAALYLQMNEKKPTWMCPVCDRGAPYDRLIIDGLFMEILNSCTDCDEIEFMEDGSWCPMRHRKEKRELCGAADLAPSLYAGSPEAAPPPPPEVEVIDLTLDSSSDEEGPPPRKHCGTPGAAHPTAGPRGALSAAPRPSSVLRCPTAALCSEFPPTIPDFTPSYTAAPELRGLDLLSFLQDDSQDTAGRSGTWGHSPPPKKGLPFIAPTDGADGPIRSAAPHRCRGRLRPTSPPHISAHGLLTVLSMNDSSTKMVSSTWFSLASILGGAQGLCWGLRAAPSPPILPPPGSALPPPASALRPPPILPPPSPGSALRPLPS", "length": 669, "header": "tr|A0A8V1ALL2-1|A0A8V1ALL2_CHICK Isoform 1 of Protein inhibitor of activated STAT 3 OS=Gallus gallus OX=9031 GN=PIAS3 PE=3 SV=1 CANONICAL=A0A8V1ALL2-1" }, "locus": { "chromosome": "25", "start_pos": 854367, "end_pos": 837427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069567.1", "url": "https://www.ensembl.org/id/ENSGALT00010069567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042828.1", "url": "https://www.ensembl.org/id/ENSGALP00010042828.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 559, "start_aa": "Thr", "end_pos": 559, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr559", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107055114", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055114", "resource": "KEGG Pathway" }, { "id": "R-GGA-3232118", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232118", "resource": "Reactome", "description": "SUMOylation of transcription factors" }, { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-GGA-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" }, { "id": "R-GGA-5696395", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696395", "resource": "Reactome", "description": "Formation of Incision Complex in GG-NER" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SDD9-1", "protein_name": "Protein inhibitor of activated STAT 3", "gene_name": "PIAS3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTPPVGSPGPLAPIPPALLAPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEIYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGNSSDNKKKVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLAPTLGSSHRSTTPAPPPGRVSNIVAPGGTLREGHGGPLPSGPSLTGCRSDIISLD", "length": 628 }, "evidence": [ { "id": "A0A8V1ALL2", "url": "https://omabrowser.org/oma/group/A0A8V1ALL2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H2S1-1", "protein_name": "E3 SUMO-protein ligase PIAS3 isoform X1", "gene_name": "Pias3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKALGPSDLSLLSLPPGTSPVGSPGPPAPIPPSLLTPGALLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITSLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGSPSENKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSATIPALPGGKGVLTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEFPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDTLGHFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPGRVSSIVSPGSSLRDGHGGPLPSGPSLSGRRSDVISLD", "length": 619 }, "evidence": [ { "id": "A0A8V1ALL2", "url": "https://omabrowser.org/oma/group/A0A8V1ALL2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O54714-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "Pias3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLTPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSAVQEGIQPESKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDTLGHFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPGRVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD", "length": 628 }, "evidence": [ { "id": "A0A8V1ALL2", "url": "https://omabrowser.org/oma/group/A0A8V1ALL2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70260-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "Pias3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPSPLASIPPTLLTPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQEGNQSENKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYSPSVITSLDEQDTLGHFFQFRGTPPHFLGPLAPTLGSSHRSATPAPAPGRVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD", "length": 628 }, "evidence": [ { "id": "A0A8V1ALL2", "url": "https://omabrowser.org/oma/group/A0A8V1ALL2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLAPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSPVQGGDPSENKKKVEVIDLTIESSSDEEDLPPTKKHCSVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDALGHFFQYRGTPSHFLGPLAPTLGSSHCSATPAPPPGRVSSIVAPGGALREGHGGPLPSGPSLTGCRSDIISLD", "length": 628 }, "evidence": [ { "id": "A0A8V1ALL2", "url": "https://omabrowser.org/oma/group/A0A8V1ALL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "SUMO ligase activity", "id": "GO:0061665", "url": 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"DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2" } ], "pmid": "" }, { "name": "protein sumoylation", "id": "GO:0016925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALL2" } ], "pmid": "" }, { "name": "positive regulation of protein sumoylation", "id": "GO:0033235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALL2", "url": 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"A0A8V1ALM1", "url": "https://www.orthodb.org/?gene=A0A8V1ALM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1APS0", "url": "https://www.orthodb.org/?gene=A0A8V1APS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19353:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19353:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AEL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AEL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1APS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCLWDPVLVMCCLRSMAAGSSLLHSRGLCSSLLSCCVLEDLTGVIAEDEELWPQLDDGDVTSGRGEDARRALQRAGSGEALMAELSERVQKVVRSSSWWERHGVDICILSCSLLALPVGFLCLRSAHAIPFLVGVLTLGVGYHTLAVKGSHLASHNALTKSKSWGKVWAVFFIEFCSAFTAEQASYNHVKLHHGYTNVIGLGDSSTWKLPFLNRYIYMFIAPLAVPIITPLVALDLLRNVEMRAALRTVCLMSLGLCCHYCLLRHVSGFQSPWSALLCMLLTRSLLAHPYIHVNIFQHIGLPMFAADRKPKRIQQMSLGVLNLPRNALLDWCFGHSLISCHVEHHLFPSLSDNMCLKIKPVVSQYLKEKRLPYNEDTYGSRLQLFLQKYEELMVHAPPITELVGIQ", "length": 406, "header": "tr|A0A8V1APS0-1|A0A8V1APS0_CHICK Isoform 1 of Fatty acid desaturase 6 OS=Gallus gallus OX=9031 GN=FADS6 PE=1 SV=1 CANONICAL=A0A8V1APS0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AEL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0/entry#A0A8V1AEL2-1", "sequence": { "sequence": "MPLEDSGAARRSGQHPCGVTGCEGTRDTLHRDELAPDVSRTGVIAEDEELWPQLDDGDVTSGRGEDARRALQRAGSGEALMAELSERVQKVVRSSSWWERHGVDICILSCSLLALPVGFLCLRSAHAIPFLVGVLTLGVGYHTLAVKGSHLASHNALTKSKSWGKVWAVFFIEHIGLPMFAADRKPKRIQQMSLGVLNLPRNALLDWCFGHSLISCHVEHHLFPSLSDNMCLKIKPVVSQYLKEKRLPYNEDTYGSRLQLFLQKYEELMVHAPPITELVGIQ", "length": 282, "header": "tr|A0A8V1AEL2-1|A0A8V1AEL2_CHICK Computationally mapped isoform of Fatty acid desaturase 6 OS=Gallus gallus OX=9031 GN=FADS6 PE=1 SV=1 CANONICAL=A0A8V1APS0-1" }, "locus": { "chromosome": "18", "start_pos": 11162433, "end_pos": 11158648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071776.1", "url": "https://www.ensembl.org/id/ENSGALT00010071776.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044466.1", "url": "https://www.ensembl.org/id/ENSGALP00010044466.1" } ] } }, { "isoform_ac": "A0A8V1ALM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0/entry#A0A8V1ALM1-1", "sequence": { "sequence": "MPLEDSGAARRSGQHPCGVTGCEGTRDTLHRDELAPDVSRTGVIAEDEELWPQLDDGDVTSGRGEDARRALQRAGSGEALMAELSERVQKVVRSSSWWERHGVDICILSCSLLALPVGFLCLRSAHAIPFLVGVLTLGVGYHTLAVKGSHLASHNALTKSKSWGKVWAVFFIEFCSAFTAEQASYNHVKLHHGYTNVIGLGDSSTWKLPFLNRYIYMFIAPLAVPIITPLVALDLLRNVEMRAALRTVCLMSLGLCCHYCLLRHVSGFQSPWSALLCMLLTRSLLAHPYIHVNIFQHIGLPMFAADRKPKRIQQMSLGVLNLPRNALLDWCFGHSLISCHVEHHLFPSLSDNMCLKIKPVVSQYLKEKRLPYNEDTYGSRLQLFLQKYEELMVHAPPITELVGIQ", "length": 405, "header": "tr|A0A8V1ALM1-1|A0A8V1APS0_CHICK Computationally mapped isoform of Fatty acid desaturase 6 OS=Gallus gallus OX=9031 GN=FADS6 PE=1 SV=1 CANONICAL=A0A8V1APS0-1" }, "locus": { "chromosome": "18", "start_pos": 11162433, "end_pos": 11158648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071775.1", "url": "https://www.ensembl.org/id/ENSGALT00010071775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044465.1", "url": "https://www.ensembl.org/id/ENSGALP00010044465.1" } ] } }, { "isoform_ac": "A0A8V1APS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0/entry#A0A8V1APS0-1", "sequence": { "sequence": "MCLWDPVLVMCCLRSMAAGSSLLHSRGLCSSLLSCCVLEDLTGVIAEDEELWPQLDDGDVTSGRGEDARRALQRAGSGEALMAELSERVQKVVRSSSWWERHGVDICILSCSLLALPVGFLCLRSAHAIPFLVGVLTLGVGYHTLAVKGSHLASHNALTKSKSWGKVWAVFFIEFCSAFTAEQASYNHVKLHHGYTNVIGLGDSSTWKLPFLNRYIYMFIAPLAVPIITPLVALDLLRNVEMRAALRTVCLMSLGLCCHYCLLRHVSGFQSPWSALLCMLLTRSLLAHPYIHVNIFQHIGLPMFAADRKPKRIQQMSLGVLNLPRNALLDWCFGHSLISCHVEHHLFPSLSDNMCLKIKPVVSQYLKEKRLPYNEDTYGSRLQLFLQKYEELMVHAPPITELVGIQ", "length": 406, "header": "tr|A0A8V1APS0-1|A0A8V1APS0_CHICK Isoform 1 of Fatty acid desaturase 6 OS=Gallus gallus OX=9031 GN=FADS6 PE=1 SV=1 CANONICAL=A0A8V1APS0-1" }, "locus": { "chromosome": "18", "start_pos": 11164574, "end_pos": 11158648, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071777.1", "url": "https://www.ensembl.org/id/ENSGALT00010071777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044467.1", "url": "https://www.ensembl.org/id/ENSGALP00010044467.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428683", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QL21-1", "protein_name": "Fatty acid desaturase 6", "gene_name": "fads6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQMKSRNSGVAGEGSAAGQEQLKPAERETLMMELSRRVQETVRLSSWWERRGIDCTILTAAFISLPAGFLLLSSSEPLCFLLGLLIMGFAHAAITVKGTHLASHGALSESPAWTDFWAVFFIEVCGSFSARAGVQAHVKMHHAHTNVIGLGDSSTWKIPFLPRSVYLFIAPLAVPIITPIVALGQLKGQSVFQIVRTIVCVFVGFFSQYYLLRSVSGLSWSSSLIVMHLCRAMFSLPYIHVNIFQHIGLPMFSATSRPKRIYQMTHGVLNLPRNPLLDWTFGHSLINCHVEHHLFPFLSDNMCLKVKPIVCEYLQEKKLPYQEDAYLSRLRLFFNNYQQLMVFAPPITELVGVQ", "length": 354 }, "evidence": [ { "id": "A0A8V1APS0", "url": "https://omabrowser.org/oma/group/A0A8V1APS0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A480WVU0-1", "protein_name": "Fatty acid desaturase 6", "gene_name": "FADS6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAAGDAPAGSRGAEALLGELEARVQDVVRASSWWERHGVDCAILALSLLALPPGFLCLRSENLLVFALGITVLGVCHYTLTVKGSHLATHGALTESKRWSKIWMLFFVEVCTSFTAEYAKYGHVKMHHAYTNVLGLGDSSTWRLPCLNRYVYMFLAPLLIPVLTPLVAVERLREVELKTALRTLGLISLGLYSHYWVLLNVSGFQSPGSALACMLITRSLLAHPYLHVNIFQHIGLPMFSRDKKPRRIHMMSLGVLNLPRLPVLDWAFGHSLISCHVEHHLFPRLSDNMCLKVKPVVSQFLHEKQLPYNEDSYLARFRLFLHRYEEFLVQTPPITELVGLQ", "length": 342 }, "evidence": [ { "id": "A0A8V1APS0", "url": "https://omabrowser.org/oma/group/A0A8V1APS0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2VE15-1", "protein_name": "Fatty acid desaturase 6", "gene_name": "FADS6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPAGGAPRESARAEALLGELEARVQEVVRASSWWERHGVDCAILALSLLALPPGFLCLRSDSPLVFALGITILGVCHYTLTVKGSHLATHGALTESRGWSKVWTLFFVEVCTSFTAEYAKYGHVKMHHGYTNVLGLGDSSTWRLPCLNRYVYMFLAPLLIPIITPLVAVERLREVELRTALRTLGLISLGLYSQYWLLLNVSGFQSPSSALACMLITRSLLAHPYLHVNIFQHIGLPMFSPDKKPRRIHMMSLGVLNLPRLPVLDWAFGHSLISCHVEHHLFPRLSDNMCLKVKPVVSQFLHEKQLPYNEDSYLARFWLFLQRYEEFMVQTPPITELVGLQ", "length": 342 }, "evidence": [ { "id": "A0A8V1APS0", "url": "https://omabrowser.org/oma/group/A0A8V1APS0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZEE9-1", "protein_name": "Fatty acid desaturase 6", "gene_name": "Fads6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPTRSAPPGDGAAEALLKELERQVQDVVRASSWWERHGVDCAILALSLLALPAGFLCLRFHNVLAFATGITILGVCHYTLTVKGSHLATHSALTESKRWSKILMIFFVEVCTAFPAEFAKFNHVNMHHGYTNVLGLGDSSTWKMPLLNRYVYMLLGPLLVPLLTPLVALEHLRKEELKTALRALGFICLGLYSQYWLFMNVSGFKSPASALACMLLARSLLAHPYLHVNIFQHIGLPMFSPDKKPRRIHMMTLGVLNLPRQPVLDWAFGHSLISCHVEHHLFPWLSDHMCLKVKPVVSKFLHDKRLPYNEDSYLARFQLFLSRYEEFMVHVPPITELVGLQ", "length": 342 }, "evidence": [ { "id": "A0A8V1APS0", "url": "https://omabrowser.org/oma/group/A0A8V1APS0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GTG6-1", "protein_name": "Fatty acid desaturase 6", "gene_name": "Fads6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPAHRASPGDGAAEALLSELERQVQDVVRASSWWERRGVDCAILALSLLALPAGFLCLRFHNVLAFATGITILGVCHYTLTVKGSHLATHGALTESKRWSKILMIFFVEVCTAFPAEFGKFNHVNMHHGYTNVVGLGDSSTWKVPSLNRYIYMFLAPLSIPILTPLVALERLRKEELRVALRTLGFISLGLYSQYWLFLNVSGFKSSSSALACMLLARSLLAHPYLHVNIFQHIGLPMFSPDKKPRRIHMMTLGVLNLPRQPVLDWAFGHSLISCHVEHHLFPWLSDRMCLKVKPLVSKFLHDKQLPYNEDSYLARFQLFLSHYEEFMVHAPSITELVGMQ", "length": 342 }, "evidence": [ { "id": "A0A8V1APS0", "url": "https://omabrowser.org/oma/group/A0A8V1APS0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q80UG1-1", "protein_name": "Fatty acid desaturase 6", "gene_name": "Fads6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVRSAPPGDGAAEALLKELERQVQDVVRASSWWERHGVDCAILALSLLALPAGFLCLRAHNILAFATGITILGVCHYTLTVKGSHLATHSALTESKRWSKILMIFFLEVCTAFSAEFAKFNHVNLHHVYTNVVGLGDSSTWKVPLLNRYVYMFLGPLLVPIITPLVALEHLRKEEPRTALRTLGFICLGLYSQYWLFMNVSGFKNPSSALACMLLTRSLLAHPYLHVNIFQHIGLPMFSPDKKPRRIHMMTLGVLNLPRQLVLDWAFGHSLISCHVEHHLFPWLSDHMCLKVKPLVSKFLHEKQLPYNEDSYLARFQLFLSRYEEFMVHVPPITELVGVQ", "length": 342 }, "evidence": [ { "id": "A0A8V1APS0", "url": "https://omabrowser.org/oma/group/A0A8V1APS0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0" } ], "pmid": "" }, { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "id": "GO:0016717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016717", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APS0" }, { "id": "PF00487", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00487" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fatty acid desaturase", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 375, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALM7-1", "uniprot_ac": "A0A8V1ALM7", "uniprot_id": "A0A8V1ALM7_CHICK", "mass": { "chemical_mass": 39381.0, "monoisotopic_mass": 39381.0 }, "refseq": { "ac": "XP_415798", "name": "leucine-rich repeat-containing protein 75A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415798" }, "gene_names": [ { "name": "LRRC75A", "type": "recommended", "evidence": [ { "id": "A0A8V1ALM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM7" } ] }, { "name": "LRRC75A", "type": "synonym", "evidence": [ { "id": "XP_415798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415798" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 75A", "type": "synonym", "evidence": [ { "id": "A0A8V1ALM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM7/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 75A", "type": "synonym", "evidence": [ { "id": "XP_415798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415798" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415798.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415798" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC75A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM7", "locus": { "chromosome": "19", "start_pos": 5619130, "end_pos": 5571694, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029325", "url": "https://www.ensembl.org/id/ENSGALG00010029325" } ] } } ], "crossref": [ { "id": "A0A8V1ALM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "417550", "url": "https://www.ncbi.nlm.nih.gov/gene/417550", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NPPDNTV", "url": "https://omabrowser.org/oma/group/NPPDNTV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALM7", "url": "https://www.orthodb.org/?gene=A0A8V1ALM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39654:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39654:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_415798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415798", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTKQTKGCQPGSTGESPPAHHRKKTSPRERGDFLASLVAKSGEKFGKGAGSLPPYHRRICMIQDMLGLVKQGKQEEATELLRHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDNIGAMEKLCRQLTYHLSPHSQWRRQGIMKRKPQSCLKAVLMGKPQDNTVDLSGIPLTLKDLERVTSYLQHSSEHIDTVELCFTELTDEMLLQLLPALCGLPHLTTLSLNGNRLTKAILRDLTETLKDPKKFPSVTWIDLGNNVDIFSLPQPFLVSLKRRCPKQGNLPTILEFGEGQVSDLENQDGLAESQEDLRGEKGEGTPLGKAEGRTVEEQGAGMPQT", "length": 354, "header": "tr|A0A8V1ALM7-1|A0A8V1ALM7_CHICK Isoform 1 of Leucine rich repeat containing 75A OS=Gallus gallus OX=9031 GN=LRRC75A PE=1 SV=1 CANONICAL=A0A8V1ALM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM7/entry#A0A8V1ALM7-1", "sequence": { "sequence": "MGTKQTKGCQPGSTGESPPAHHRKKTSPRERGDFLASLVAKSGEKFGKGAGSLPPYHRRICMIQDMLGLVKQGKQEEATELLRHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDNIGAMEKLCRQLTYHLSPHSQWRRQGIMKRKPQSCLKAVLMGKPQDNTVDLSGIPLTLKDLERVTSYLQHSSEHIDTVELCFTELTDEMLLQLLPALCGLPHLTTLSLNGNRLTKAILRDLTETLKDPKKFPSVTWIDLGNNVDIFSLPQPFLVSLKRRCPKQGNLPTILEFGEGQVSDLENQDGLAESQEDLRGEKGEGTPLGKAEGRTVEEQGAGMPQT", "length": 354, "header": "tr|A0A8V1ALM7-1|A0A8V1ALM7_CHICK Isoform 1 of Leucine rich repeat containing 75A OS=Gallus gallus OX=9031 GN=LRRC75A PE=1 SV=1 CANONICAL=A0A8V1ALM7-1" }, "locus": { "chromosome": "19", "start_pos": 5617381, "end_pos": 5572522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070924.1", "url": "https://www.ensembl.org/id/ENSGALT00010070924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043615.1", "url": "https://www.ensembl.org/id/ENSGALP00010043615.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZS41-1", "protein_name": "Leucine rich repeat containing 75A", "gene_name": "LRRC75A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGAGLPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQWRRHRGLVKRKPQACLKAVLAGSPQDNTVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRALLRDLTDALKDPSKFPSVTWIDLGNNVDIFSLPQPFLLSLRKRCPKQGHLPTILELGEGPGCGDEARDETVGQEDPGGDPGAPTRAQESRETGGAAQT", "length": 343 }, "evidence": [ { "id": "A0A8V1ALM7", "url": "https://omabrowser.org/oma/group/A0A8V1ALM7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BFQ5-1", "protein_name": "Leucine rich repeat containing 75A", "gene_name": "LRRC75A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTRQTKGSLAERAGPGAAPGPRRERPDFWASLLLRAGDKAGRAGAGAGLPPYHRRVGMVQELLRMLHQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQWRRHRGLVKRKPQACLKAVLAGSPPDNTVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRMTTLALNGNRLTRALLRDLTDALRDPRKFPSVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGSGHETQDETLGPEDPGGGPETPARDQEGRETVGATQT", "length": 345 }, "evidence": [ { "id": "A0A8V1ALM7", "url": "https://omabrowser.org/oma/group/A0A8V1ALM7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TSF4-1", "protein_name": "Leucine-rich repeat-containing protein 75A", "gene_name": "Lrrc75a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGSGLPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDAMGAMEKLCRQLTYHLSPHSQWRRHRGLKRKPQACLKALLSGNPPDNMVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRALLRDLTDTLKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGTGEEAREGTDQQDPIGSPVTPARGQESTECVIQT", "length": 339 }, "evidence": [ { "id": "A0A8V1ALM7", "url": "https://omabrowser.org/oma/group/A0A8V1ALM7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NAA5-1", "protein_name": "Leucine-rich repeat-containing protein 75A", "gene_name": "LRRC75A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGAGMPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQWRRHRGLVKRKPQACLKAVLAGSPPDNTVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRAVLRDLTDILKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGSGEEVREGTVGQEDPGGGPVAPAEDHHEGKETVAAAQT", "length": 344 }, "evidence": [ { "id": "A0A8V1ALM7", "url": "https://omabrowser.org/oma/group/A0A8V1ALM7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANB3-1", "uniprot_ac": "A0A8V1ANB3", "uniprot_id": "A0A8V1ANB3_CHICK", "mass": { "chemical_mass": 67610.0, "monoisotopic_mass": 67610.0 }, "refseq": {}, "gene_names": [ { "name": "OTOP2", "type": "recommended", "evidence": [ { "id": "A0A8V1ANB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3" } ] } ], "protein_names": [ { "name": "Otopetrin 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ANB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OTOP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3", "locus": { "chromosome": "18", "start_pos": 11190420, "end_pos": 11183511, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029679", "url": "https://www.ensembl.org/id/ENSGALG00010029679" } ] } } ], "crossref": [ { "id": "A0A8V1ANB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "422111", "url": "https://www.ncbi.nlm.nih.gov/gene/422111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422111", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICRMILC", "url": "https://omabrowser.org/oma/group/ICRMILC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALM9", "url": "https://www.orthodb.org/?gene=A0A8V1ALM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANB3", "url": "https://www.orthodb.org/?gene=A0A8V1ANB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ALM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDEPVRKDSEIRRPNSSMGCGSKDDKASLASSQTMSLSPQPHQPSAPGSKEVWKKGGRMFSILLAVHLALLACTLVSSGAFERIAVHDYDVFFLLTVMMLIVIIWIIFYLISTSRCPDAILCKDSHAGPVWLRGGLILFAIFSLVMDVFKIGYYSSFYSCLSAIKIMYPIVQAIFVVVQTYFLWISAKDCVHVHLNVTRCGLMLTLTTNLAVWMSAVTDESVHKAHSKLKKNTTEELFRWLLKVGMRSGSTEACNCNSQICQIFKNGYFWLYPFNIEYSLFASAMVYVMWKNVGRFIDHHSHHIQRLKFRLFRRTFFVGIVLGLIILVSGLGVLIVYEVQVNSSTEPSKKGQALTMYYIFNIVCLGLMSLVCIGGSVIYRFDKRDMDRHKNPTRTLDVALLMGAALGQYAISYYSIVAIVASTPRDAISALNLTYALLMIAQHTFQNIFIIEGLHRQPPKEDHKRSSHQKELYGLTFVNVSAVSLRVPDSGSVSALSTGTEGTIPSDLVRSLTAPKKINWRRKLLREISMFLLLCNIIVSTCREKSSSGWGGAEHRGISTEERMCPCKNCPSCTPTTQEAGLFVPVRAGSCNCLRSHLKEQVF", "length": 604, "header": "tr|A0A8V1ANB3-1|A0A8V1ANB3_CHICK Isoform 1 of Otopetrin 2 OS=Gallus gallus OX=9031 GN=OTOP2 PE=3 SV=1 CANONICAL=A0A8V1ANB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3/entry#A0A8V1ALM9-1", "sequence": { "sequence": "MSDEPVRKDSEIRRPNSSMGCGSKDDKASLASSQTMSLSPQPHQPSAPGSKEVWKKGGRMFSILLAVHLALLACTLVSSGAFERIAVHDYDVFFLLTVMMLIVIIWIIFYLISTSRCPDAILCKDSHAGPVWLRGGLILFAIFSLVMDVFKIGYYSSFYSCLSAIKIMYPIVQAIFVVVQTYFLWISAKDCVHVHLNVTRCGLMLTLTTNLAVWMSAVTDESVHKAHSKLKKNTTEELFRWLLKVGMRSGSTEACNCNSQICQIFKNGYFWLYPFNIEYSLFASAMVYVMWKNVGRFIDHHSHHIQRLKFRLFRRTFFVGIVLGLIILVSGLGVLIVYEVQVNSSTEPSKKGQALTMYYIFNIVCLGLMSLVCIGGSVIYRFDKRDMDRHKNPTRTLDVALLMGAALGQYAISYYSIVAIVASTPRDAISALNLTYALLMIAQHTFQNIFIIEGLHRQPPKEDHKRSSHQKELYGLTFVNVSAVSLRVPDSGSVSALSTGTEGTIPSDLVRSLTAPKKINWRRKLLREISMFLLLCNIILWIMPAFGARPHFDNDTELNFYGDSMWPAIVDICLPFGIFYRMHAVASLLEVCIMS", "length": 595, "header": "tr|A0A8V1ALM9-1|A0A8V1ANB3_CHICK Computationally mapped isoform of Otopetrin 2 OS=Gallus gallus OX=9031 GN=OTOP2 PE=3 SV=1 CANONICAL=A0A8V1ANB3-1" }, "locus": { "chromosome": "18", "start_pos": 11189416, "end_pos": 11184477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071785.1", "url": "https://www.ensembl.org/id/ENSGALT00010071785.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044475.1", "url": "https://www.ensembl.org/id/ENSGALP00010044475.1" } ] } }, { "isoform_ac": "A0A8V1ANB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3/entry#A0A8V1ANB3-1", "sequence": { "sequence": "MSDEPVRKDSEIRRPNSSMGCGSKDDKASLASSQTMSLSPQPHQPSAPGSKEVWKKGGRMFSILLAVHLALLACTLVSSGAFERIAVHDYDVFFLLTVMMLIVIIWIIFYLISTSRCPDAILCKDSHAGPVWLRGGLILFAIFSLVMDVFKIGYYSSFYSCLSAIKIMYPIVQAIFVVVQTYFLWISAKDCVHVHLNVTRCGLMLTLTTNLAVWMSAVTDESVHKAHSKLKKNTTEELFRWLLKVGMRSGSTEACNCNSQICQIFKNGYFWLYPFNIEYSLFASAMVYVMWKNVGRFIDHHSHHIQRLKFRLFRRTFFVGIVLGLIILVSGLGVLIVYEVQVNSSTEPSKKGQALTMYYIFNIVCLGLMSLVCIGGSVIYRFDKRDMDRHKNPTRTLDVALLMGAALGQYAISYYSIVAIVASTPRDAISALNLTYALLMIAQHTFQNIFIIEGLHRQPPKEDHKRSSHQKELYGLTFVNVSAVSLRVPDSGSVSALSTGTEGTIPSDLVRSLTAPKKINWRRKLLREISMFLLLCNIIVSTCREKSSSGWGGAEHRGISTEERMCPCKNCPSCTPTTQEAGLFVPVRAGSCNCLRSHLKEQVF", "length": 604, "header": "tr|A0A8V1ANB3-1|A0A8V1ANB3_CHICK Isoform 1 of Otopetrin 2 OS=Gallus gallus OX=9031 GN=OTOP2 PE=3 SV=1 CANONICAL=A0A8V1ANB3-1" }, "locus": { "chromosome": "18", "start_pos": 11188474, "end_pos": 11184477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071784.1", "url": "https://www.ensembl.org/id/ENSGALT00010071784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044474.1", "url": "https://www.ensembl.org/id/ENSGALP00010044474.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422111", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9VQN3-1", "protein_name": "Otopetrin-like b, isoform A", "gene_name": "OtopLb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLINLKSKDMYDEPINLWRTKQRVHYHHDVISKGNDSHRSSDACEYITISAPKKSGSFSRSPPSSLPTSVPGTPRHSVAATSNQVIRYARTSCDHCGHHSIPVMSPHPISPLAKSQTNLDLVEHGSQRQALLPLPTVGMHHEDSACTLQVSRRPSLLLQEILTQRPPLFGRRDGNGFLSPRTAKNGNLQGTASGSTATINFQSGATSARNGSTAFFDNGAKSFQAKQQKDKNRRTGNDAISSALSATYCKLLVLLGVCLPITEVISDQIPTYVYQGFYVYLYVGSILFVIFLYISAFRNRSLFNALKDYHEKNSNVHLKHKVTHFGSFYLRVGAIAFAIGTMVYSGLEFGQFFELNGHPGCRDVFVAITPICRMVLCIAQVQFIFLNTTYMDMARHKVTSRFGLMHMVATNLCEWLYVLVEETKHEIFHISQHEVDPAHDLVIHNSSMSRTDWAAVNESLHQHHHHHALNNTLVANVSSVIVNMTITPSPTPAAFSGCSRTTIMGALVQQLSPFLFPCTIEYSLICAVILFEMWKTVKSIPDIDKTRKNSVKPAAAKPAHHFSVDCSQSHKGLFFGILIIVMTIISMIMYFVLYTQPGYELVATQEVTLWETFMYFMCAAAVITGMILMRDLRYIKNTSDEHHSMDLDNLLLIVAQTGVYLYGMFSILGSYFAKWDTVPDRVEGIIAEVFGVVQTSLQTMFILHSSHRRCRGTNQVRRKPGREIITFLLVANIAIWFVNTLIKGRAVFRESHLEFFGVWGWTIITHISMPLAIFYRFHSTICLFEVWKITYKAKAH", "length": 797 }, "evidence": [ { "id": "A0A8V1ANB3", "url": "https://omabrowser.org/oma/group/A0A8V1ANB3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton channel activity", "id": "GO:0015252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proton transmembrane transport", "id": "GO:1902600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 480, "end_pos": 482 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALN7-1", "uniprot_ac": "A0A8V1ALN7", "uniprot_id": "A0A8V1ALN7_CHICK", "mass": { "chemical_mass": 35983.0, "monoisotopic_mass": 35983.0 }, "refseq": {}, "gene_names": [ { "name": "KCTD2", "type": "recommended", "evidence": [ { "id": "A0A8V1ALN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7" } ] } ], "protein_names": [ { "name": "Potassium channel tetramerization domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ALN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7", "locus": { "chromosome": "18", "start_pos": 11269415, "end_pos": 11261900, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029686", "url": "https://www.ensembl.org/id/ENSGALG00010029686" } ] } } ], "crossref": [ { "id": "A0A8V1ALN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007934", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007934", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALN7", "url": "https://www.orthodb.org/?gene=A0A8V1ALN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F7ATV4", "url": "https://www.orthodb.org/?gene=F7ATV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14958:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14958:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ALN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F7ATV4", "url": "https://www.uniprot.org/uniprotkb/F7ATV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F7ATV4-1", "url": "https://www.uniprot.org/uniprotkb/F7ATV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGLPSLLVPLSSHRSSLTFTDRHYRPLALPSDAPEALPSAANQSAALAETHHAAPHTEVLRAPEAAAAGRGGDGGVGAVRAAAMAELAAAEGPPRGRTPSPGPGGVPGPPSPRSAAPGFSGTMLSPGPAGAARPPAASKWVRLNVGGTYFVSTRQTLCREPKSFLCRLCCQDGPELGSDKDETGAYLIDRDPTYFGPILNYLRHGKLIINKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQVMHGPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVKEPSEKAKILQERGSRM", "length": 335, "header": "tr|A0A8V1ALN7-1|A0A8V1ALN7_CHICK Isoform 1 of Potassium channel tetramerization domain containing 2 OS=Gallus gallus OX=9031 GN=KCTD2 PE=4 SV=1 CANONICAL=A0A8V1ALN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7/entry#A0A8V1ALN7-1", "sequence": { "sequence": "MEPGLPSLLVPLSSHRSSLTFTDRHYRPLALPSDAPEALPSAANQSAALAETHHAAPHTEVLRAPEAAAAGRGGDGGVGAVRAAAMAELAAAEGPPRGRTPSPGPGGVPGPPSPRSAAPGFSGTMLSPGPAGAARPPAASKWVRLNVGGTYFVSTRQTLCREPKSFLCRLCCQDGPELGSDKDETGAYLIDRDPTYFGPILNYLRHGKLIINKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQVMHGPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVKEPSEKAKILQERGSRM", "length": 335, "header": "tr|A0A8V1ALN7-1|A0A8V1ALN7_CHICK Isoform 1 of Potassium channel tetramerization domain containing 2 OS=Gallus gallus OX=9031 GN=KCTD2 PE=4 SV=1 CANONICAL=A0A8V1ALN7-1" }, "locus": { "chromosome": "18", "start_pos": 11266079, "end_pos": 11262099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071795.1", "url": "https://www.ensembl.org/id/ENSGALT00010071795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044485.1", "url": "https://www.ensembl.org/id/ENSGALP00010044485.1" } ] } }, { "isoform_ac": "F7ATV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALN7/entry#F7ATV4-1", "sequence": { "sequence": "MEPGLPSLLVPLSSHRSSLTFTDRHYRPLALPSDAPEALPSAANQSAALAETHHAAPHTEVLRAPEAAAAGRGGDGGVGAVRAAAMAELAAAEGPPRGRTPSPGPGGVPGPPSPRSAAPGFSGTMLSPGPAGAARPPAASKWVRLNVGGTYFVSTRQTLCREPKSFLCRLCCQDGPELGSDKDETGAYLIDRDPTYFGPILNYLRHGKLIINKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVKEPSEKAKILQERGSRM", "length": 332, "header": "tr|F7ATV4-1|F7ATV4_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 2 OS=Gallus gallus OX=9031 GN=KCTD2 PE=4 SV=1 CANONICAL=A0A8V1ALN7-1" }, "locus": { "chromosome": "18", "start_pos": 11266079, "end_pos": 11262099, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071796.1", "url": "https://www.ensembl.org/id/ENSGALT00010071796.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044486.1", "url": "https://www.ensembl.org/id/ENSGALP00010044486.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], 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22386.0, "monoisotopic_mass": 22386.0 }, "refseq": { "ac": "XP_040505809", "name": "ADP-ribosylation factor-like protein 16 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505809" }, "gene_names": [ { "name": "ARL16", "type": "recommended", "evidence": [ { "id": "A0A8V1ALR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4" } ] }, { "name": "ARL16", "type": "synonym", "evidence": [ { "id": "XP_040505809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505809" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 16 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040505809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505809" } ] }, { "name": "ARF like GTPase 16", "type": "synonym", "evidence": [ { "id": "A0A8V1ALR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505809" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARL16", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4", "locus": { "chromosome": "18", "start_pos": 10512325, "end_pos": 10514606, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029346", "url": "https://www.ensembl.org/id/ENSGALG00010029346" } ] } } ], "crossref": [ { "id": "A0A8V1ALR4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "768991", "url": "https://www.ncbi.nlm.nih.gov/gene/768991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETTFSMP", "url": "https://omabrowser.org/oma/group/ETTFSMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALR4", "url": "https://www.orthodb.org/?gene=A0A8V1ALR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46688", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46688", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46688:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46688:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505809", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAARPGPTCLLLGATGVGKSLLGKRLRNIRASWGSRGAGPGWGCAARFCPVLNAPAQLCSRDGAKELGEPPATLPTVGTNLTDLTLHRRVTLRELGGCMGPIWPSYYGECSAVLFVIDAANPTQVSSSCVQLLSLLSAEQLAAVPVLILFNKIDLPCYMSLVEMKSLFRMQDIVSCAMQPITILETSARDGTGLADVLQWLQTTLRDPS", "length": 211, "header": "tr|A0A8V1ALR4-1|A0A8V1ALR4_CHICK Isoform 1 of ARF like GTPase 16 OS=Gallus gallus OX=9031 GN=ARL16 PE=4 SV=1 CANONICAL=A0A8V1ALR4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4/entry#A0A8V1ALR4-1", "sequence": { "sequence": "MAGAARPGPTCLLLGATGVGKSLLGKRLRNIRASWGSRGAGPGWGCAARFCPVLNAPAQLCSRDGAKELGEPPATLPTVGTNLTDLTLHRRVTLRELGGCMGPIWPSYYGECSAVLFVIDAANPTQVSSSCVQLLSLLSAEQLAAVPVLILFNKIDLPCYMSLVEMKSLFRMQDIVSCAMQPITILETSARDGTGLADVLQWLQTTLRDPS", "length": 211, "header": "tr|A0A8V1ALR4-1|A0A8V1ALR4_CHICK Isoform 1 of ARF like GTPase 16 OS=Gallus gallus OX=9031 GN=ARL16 PE=4 SV=1 CANONICAL=A0A8V1ALR4-1" }, "locus": { "chromosome": "18", "start_pos": 10514583, "end_pos": 10513723, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070971.1", "url": "https://www.ensembl.org/id/ENSGALT00010070971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043662.1", "url": "https://www.ensembl.org/id/ENSGALP00010043662.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AHL5-1", "protein_name": "ADP-ribosylation factor like GTPase 16", "gene_name": "Arl16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLLLGAAGVGKTLLVKRLQKLSSGDGKGDLGEPPPTRPTVGTNLTDIVAHRKITIRELGGCMSPIWSSYYGNCHSLLFMMDASNPTQLSASCMQLLGLLSAEELAKASVLILFNKIDLPSYMTVEEIKSLMRLPDIIACAKQNITTVEISARNGTGLATVLLWLRNQHRHSS", "length": 173 }, "evidence": [ { "id": "A0A8V1ALR4", "url": "https://omabrowser.org/oma/group/A0A8V1ALR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B1ATY8-1", "protein_name": "ADP-ribosylation factor-like protein 16", "gene_name": "Arl16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLLLGAAGVGKTLLVKRLQKLSSGDGKGDLGEPPPTRPTVGTNLTDIVAHRKITIRELGGCMSPIWSSYYGNCHSLLFMMDASNPTQLSASCMQLLGLLSAEELEKASVLILFNKIDLPCYMTMEEMKSLMRLPDIIACAKQNITAVEISARNGTGLATVLLWLQNQHRHSS", "length": 173 }, "evidence": [ { "id": "A0A8V1ALR4", "url": "https://omabrowser.org/oma/group/A0A8V1ALR4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1QAH7-1", "protein_name": "ADP-ribosylation factor-like protein 16", "gene_name": "arl16", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCLLLGATGVGKTLLLKRLQKLCQMDPCADLGEAPVTLPTVGTNLTDLILKKKKKKITVRELGGCMGPIWPKYYLDCKSVIFVVDCVNVEQISSSCVQLLSVLSAESLLSAAVLILFNKRDLLCSMSLVELKSLFRMDDIIKSAPQFVTILEVSARSGQGLQDVLHWLSSNLSDTSD", "length": 177 }, "evidence": [ { "id": "A0A8V1ALR4", "url": "https://omabrowser.org/oma/group/A0A8V1ALR4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0P5N6-1", "protein_name": "ADP-ribosylation factor-like protein 16", "gene_name": "ARL16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCLLLGATGVGKTLLVKRLQEVSSRDGKGDLGEPPPTRPTVGTNLTDIVAQRKITIRELGGCMGPIWSSYYGNCRSLLFVMDASDPTQLSASCVQLLGLLSAEQLAEASVLILFNKIDLPCYMSTEEMKSLIRLPDIIACAKQNITTAEISAREGTGLAGVLAWLQATHRAND", "length": 173 }, "evidence": [ { "id": "A0A8V1ALR4", "url": "https://omabrowser.org/oma/group/A0A8V1ALR4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPP8-1", "protein_name": "ADP-ribosylation factor-like protein 16", "gene_name": "Dmel\\CG13692", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTCICLGPKRAGKTHLLKALQDPESIDETTFSMPTIGTGIYRIHFPTKSPNGDKNKPPPSEAPANIPHGGKNLPKSIQILEIGGSMAPLWRQYFEDVKKLIYVVDTSNLCQISAAGVLFYSILTEPRLQHNTKILLVLAKMDYSYRQMRNEALLMLQMQKLQKQIRQQVTIVEASAVTKVGLDPIYDWLQRP", "length": 193 }, "evidence": [ { "id": "A0A8V1ALR4", "url": "https://omabrowser.org/oma/group/A0A8V1ALR4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V1ALR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4#function" }, { "id": "A0A8V1ALR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALR4" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 78, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 78, "end_pos": 78, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALS2-1", "uniprot_ac": "A0A8V1ALS2", "uniprot_id": "A0A8V1ALS2_CHICK", "mass": { "chemical_mass": 21103.0, "monoisotopic_mass": 21103.0 }, "refseq": { "ac": "XP_001232214", "name": "39S ribosomal protein L12, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232214" }, "gene_names": [ { "name": "MRPL12", "type": "recommended", "evidence": [ { "id": "A0A8V1ALS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ] }, { "name": "MRPL12", "type": "synonym", "evidence": [ { "id": "XP_001232214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232214" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein bL12m", "type": "recommended", "evidence": [ { "id": "A0A8V1ALS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L12, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_001232214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232214" }, { "id": "A0A8V1ALS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001232214.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232214" } ] }, { "annotation": "As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2#function" }, { "database": "UniProtKB", "id": "ARBA00058301", "url": "https://www.uniprot.org/uniprotkb/ARBA00058301#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL12", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2", "locus": { "chromosome": "18", "start_pos": 10527592, "end_pos": 10524231, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029350", "url": "https://www.ensembl.org/id/ENSGALG00010029350" } ] } } ], "crossref": [ { "id": "A0A8V1ALS2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00387", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00387", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769031", "url": "https://www.ncbi.nlm.nih.gov/gene/769031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769031", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769031", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LEDKWGV", "url": "https://omabrowser.org/oma/group/LEDKWGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALS2", "url": "https://www.orthodb.org/?gene=A0A8V1ALS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45987", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45987", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45987:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45987:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00542", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00542", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001232214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232214", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPAARLALPLPPRLARRPPLSWRWGAARPLGTGRARRRSEALAGEALAGAPLDTAAKEYSPKVRQLVRDIAGLTLLEVADLNALLKETLKIPDVGVMPAGAAAHLPAQAAPQEEEEAIPMKKEKTHFSVRLTELKATDKVKLIKEVKNFVPGINLVQAKKLVESLPQEIKANVSKEEAEKIKTALEAAGGTVVLE", "length": 196, "header": "tr|A0A8V1ALS2-1|A0A8V1ALS2_CHICK Isoform 1 of Large ribosomal subunit protein bL12m OS=Gallus gallus OX=9031 GN=MRPL12 PE=1 SV=1 CANONICAL=A0A8V1ALS2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2/entry#A0A8V1ALS2-1", "sequence": { "sequence": "MLPAARLALPLPPRLARRPPLSWRWGAARPLGTGRARRRSEALAGEALAGAPLDTAAKEYSPKVRQLVRDIAGLTLLEVADLNALLKETLKIPDVGVMPAGAAAHLPAQAAPQEEEEAIPMKKEKTHFSVRLTELKATDKVKLIKEVKNFVPGINLVQAKKLVESLPQEIKANVSKEEAEKIKTALEAAGGTVVLE", "length": 196, "header": "tr|A0A8V1ALS2-1|A0A8V1ALS2_CHICK Isoform 1 of Large ribosomal subunit protein bL12m OS=Gallus gallus OX=9031 GN=MRPL12 PE=1 SV=1 CANONICAL=A0A8V1ALS2-1" }, "locus": { "chromosome": "18", "start_pos": 10527353, "end_pos": 10524280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070981.1", "url": "https://www.ensembl.org/id/ENSGALT00010070981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043672.1", "url": "https://www.ensembl.org/id/ENSGALP00010043672.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769031", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U6S6-1", "protein_name": "Large ribosomal subunit protein bL12m", "gene_name": "MRPL12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPAAASSLWGPCFGLRAAALRVARHQGPRLCGVRLMRCSSHRKGEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGFMPMGAVAPGAPPAAAAPEAAEEDLPKRKEQTHFTVRLTEAKPVDKVKLIKEIKSHIQGINLVQAKKLVESLPQEIKANVPKAEAEKIKAALEAVGGTVVLE", "length": 198 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P36210-1", "protein_name": "Large ribosomal subunit protein bL12cz", "gene_name": "RPL12A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTLSIATTIRSSSYPTLASINHFPSRTTTIEFPSRFGGGSSSTLTHRATHLRPIAAVEAPEKIEKIGSEISSLTLEEARILVDYLQDKFGVSPLSLAPAAAAVAAPADGGAAAVVEEQTEFDVVINEVPSSSRIAVIKAVRALTSLALKEAKELIEGLPKKFKEGITKDEAEEAKKTLEEAGAKVSIA", "length": 191 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P52815-1", "protein_name": "Large ribosomal subunit protein bL12m", "gene_name": "MRPL12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPAAARPLWGPCLGLRAAAFRLARRQVPCVCAVRHMRSSGHQRCEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLVPMGGVMSGAVPAAAAQEAVEEDIPIAKERTHFTVRLTEAKPVDKVKLIKEIKNYIQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE", "length": 198 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53163-1", "protein_name": "Large ribosomal subunit protein bL12m", "gene_name": "MNP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLRILAKRSSSIWMKTRVTPALISPITITTRFNSTTTTAPSHKDDVRPVDPKISKIVQDISQLTLLETSSLINELKTVLNIPEISMPMGGFMAGAAGAGAGNVPSSTGEAGSGAEEEAKPEAKTVFTVKLDSFDTKTKAKVIKEVKGLLGLSLVEAKKFVEAAPKVLKENVAKDDAEKIKKTLEDLGAKVSLE", "length": 194 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7YR75-1", "protein_name": "Large ribosomal subunit protein bL12m", "gene_name": "MRPL12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPSATSLLRGPCLGLRAAALRLVRQQVPHVCAVRLMRCSSHRRGEALTGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLMPMGGMVPGAAPAPTAPEAAEEDVPKQKERTHFTVRLTEAKPVDKVKLIKEIKNYVQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE", "length": 198 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86KA1-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISRVSLNKCFSTLSKLKCNNNTLYSTRLFTTEPEKVNLKLTTIENGKSSTEVADLVERISKLSILDVMDLTQHLQKKLSIPDIDLSSLGSGAPAGGAAPAAAAAPAAVAKTDFQVRLVKVPDGAKYKIIKELREVKPSLSLMETKGLVEKIPSVIADKVSKEEAEKIIAKLKASGAELEMA", "length": 182 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DB15-1", "protein_name": "Large ribosomal subunit protein bL12m", "gene_name": "Mrpl12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVAASRCLWGPRLGLRGAALRLARQQMPSVCAARQLRSSSHRRSEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLMPMGGMVPGPVSAAAPASEAAEEEDVPKQKERTHFTVRLTEAKPVDKVKLIKEIKNYVQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE", "length": 201 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSR5-1", "protein_name": "Mitochondrial ribosomal protein L12", "gene_name": "mRpL12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHITRLALRQISRQVQLHRMYSAAAPAAAVSGAEKLVPPAPEGAAKPPNPKLDSIVNNIAALNLLEVAELSTLLKQKLNLPETAFAPQFAAGPARAAPAEDEEEAAPKKVQTSFKVKLVKFDEKQKVALIKEVKNLLEGMNLVQAKKFVESAPTIVKEDIPKEEAEKLKEALSKAGAIIEIE", "length": 182 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "X1WHQ5-1", "protein_name": "Large ribosomal subunit protein bL12m", "gene_name": "mrpl12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMYCSRHCVRLALRAAVNTHRHSVQRTALYAQRTLKTSSVSAVDAIATPHLDGTPKEYSPKIQQLVNDIASLTLIEVSDLNELLKKTLNIQDVGMMSMGSMAAVPVAPPAELTEGLAEEEVAPAKKEKTHFTIKLTEFKAADKVKLIKEVKNCMEGINLVQAKKLVESLPQEIRTNISKDEAEKLKSALEAAGGTVVLE", "length": 199 }, "evidence": [ { "id": "A0A8V1ALS2", "url": "https://omabrowser.org/oma/group/A0A8V1ALS2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "pmid": "" }, { "name": "mitochondrial transcription", "id": "GO:0006390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006390", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" }, { "id": "PF00542", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00542" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein bL12 C-terminal", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 195, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ALS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALS2" }, { "id": "PF16320", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16320" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein bL12 oligomerization", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 111, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALT3-1", "uniprot_ac": "A0A8V1ALT3", "uniprot_id": "A0A8V1ALT3_CHICK", "mass": { "chemical_mass": 57747.0, "monoisotopic_mass": 57747.0 }, "refseq": { "ac": "XP_046758568", "name": "apoptosis-inducing factor 3-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758568" }, "gene_names": [ { "name": "LOC124417312", "type": "recommended", "evidence": [ { "id": "A0A8V1ALT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3" } ] }, { "name": "LOC124417312", "type": "synonym", "evidence": [ { "id": "XP_046758568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758568" } ] } ], "protein_names": [ { "name": "Rieske domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ALT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3/entry#names_and_taxonomy" } ] }, { "name": "apoptosis-inducing factor 3-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046758568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758568" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC124417312", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3", "locus": {} } ], "crossref": [ { "id": "A0A8V1ALT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03478", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03478", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF07992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046758568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDCNDTVTAEVCREDDIGDGELCEVMVAGYPVLLVRDKMEFSALGSRCPHYGAPLSKGVLRGHRLRCPWHGSCFNIKTGDIEEYPSLDCLPCFKVTVEDGKVFVTAKKKDLESSLRVKDMSKRCLLNRNTMLLLGGGVAALTCAETLRQEGFTGRIIMATKEKHAPYDKSKLSKEMNLKAEDIYLRKPEFLCAHGIELWTEKEAVSVDFQKQKVHFMYGSSQKYNQLLIATGGHSSFLKVPGADLQNVCHLQTPEDASKVLELASGKNLVIVGASFIGMETAAFLSDKAAAISVVEKQEFPFQKTLGPQVGGVVLKMLQSKGVKFYMKKELHELKGKDGKVAEAILASGEKLPADVVVVGIGVTPNSAFLKGTTIAKDNSGAILVDLRMQTNIPNVFAAGDVVSFPVALLNGDHSSIHHQQVAEAHGSIAAFNMLKKQKELHTVPFFWTTMLGRSIHYAGCGKGYTDTVLKGSLEEQKFLIFYLKDGLVTAAASLNCDPVVSLIAEVLYLGEKISKEEAEAYDINNICL", "length": 529, "header": "tr|A0A8V1ALT3-1|A0A8V1ALT3_CHICK Isoform 1 of Rieske domain-containing protein OS=Gallus gallus OX=9031 GN=LOC124417312 PE=3 SV=1 CANONICAL=A0A8V1ALT3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3/entry#A0A8V1ALT3-1", "sequence": { "sequence": 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"A0A8V1ALT3", "url": "https://omabrowser.org/oma/group/A0A8V1ALT3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H", "id": "GO:0016651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016651", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALT3" }, { "id": "PS51296", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rieske", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 104, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALU9-1", "uniprot_ac": "A0A8V1ALU9", "uniprot_id": "A0A8V1ALU9_CHICK", "mass": { "chemical_mass": 27521.0, "monoisotopic_mass": 27521.0 }, "refseq": {}, "gene_names": [ { "name": "LOC425969", "type": "recommended", "evidence": [ { "id": "A0A8V1ALU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU9" } ] } ], "protein_names": [ { "name": "Epidermal differentiation protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ALU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC425969", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU9", "locus": {} } ], "crossref": [ { "id": "A0A8V1ALU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1ALU9", "url": "https://www.orthodb.org/?gene=A0A8V1ALU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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SV=1 CANONICAL=A0A8V1ALU9-1" }, "locus": { "chromosome": "25", "start_pos": 1687032, "end_pos": 1686259, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069819.1", "url": "https://www.ensembl.org/id/ENSGALT00010069819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042945.1", "url": "https://www.ensembl.org/id/ENSGALP00010042945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALV0-1", "uniprot_ac": "A0A8V1ALV0", "uniprot_id": "A0A8V1ALV0_CHICK", "mass": { "chemical_mass": 41867.0, "monoisotopic_mass": 41867.0 }, "refseq": { "ac": "NP_001121535", "name": "galanin receptor type 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121535" }, "gene_names": [ { "name": "GALR2", "type": "recommended", "evidence": [ { "id": "A0A8V1ALV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ] }, { "name": "GALR2", "type": "synonym", "evidence": [ { "id": "NP_001121535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121535" } ] } ], "protein_names": [ { "name": "Galanin receptor 2", "type": "synonym", "evidence": [ { "id": "A0A8V1ALV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0/entry#names_and_taxonomy" } ] }, { "name": "galanin receptor type 2", "type": "synonym", "evidence": [ { "id": "NP_001121535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121535" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EU525170.1, SRR13267652.6533.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000316.1. On Sep 23, 2021 this sequence version replaced NP_001121535.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001121535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121535" } ] }, { "annotation": "That both cGalR2 and cGalR2-L are capable of activating the three examined signal transduction pathways, and are hence potentially coupled to the Gs and Gq-class G proteins.", "evidence": [ { "database": "RefSeq", "id": "NP_001121535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121535" }, { "database": "PubMed", "id": "22982974", "url": "https://glygen.org/publication/PubMed/22982974" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GALR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0", "locus": { "chromosome": "18", "start_pos": 5157841, "end_pos": 5162454, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029715", "url": "https://www.ensembl.org/id/ENSGALG00010029715" } ] } } ], "crossref": [ { "id": "A0A8V1ALV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15097", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15097", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770030", "url": "https://www.ncbi.nlm.nih.gov/gene/770030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770030", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LTYTRTI", "url": "https://omabrowser.org/oma/group/LTYTRTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALV0", "url": "https://www.orthodb.org/?gene=A0A8V1ALV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001121535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGSAAGSDEGWHPESVLIPLAYLLIFLVGTVGNCLVLAVLLRNGQVKNTTNLFILNLGVADLCFILFCVPFQATIYTLEGWVFGSFLCKAVHFFIYLTMYASSFTLATVSLDRYLAIRYPLHSRELRTPRNALVAICFIWALSIIFSSPYLSYYQQLQLANLTVCHPVWATSQRKVMDLCTFIFSYIIPVLILSLTYTRTIRYLWRSVDPLQEMSESKKAKRKVTRMIVIVAVLFCLCWLPHHLVILCFWFGYFPLNHTTYVLRIVSHLISYANSCVNPIVYALVSKHFRKGFKKIFICLLHKKAANKVHVAQGTNTVSMLEAELSEVTRLSDAGPGCSSVRCKAQPWGEAALGGRQQRADGSFITFDVT", "length": 371, "header": "tr|A0A8V1ALV0-1|A0A8V1ALV0_CHICK Isoform 1 of Galanin receptor 2 OS=Gallus gallus OX=9031 GN=GALR2 PE=3 SV=1 CANONICAL=A0A8V1ALV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0/entry#A0A8V1ALV0-1", "sequence": { "sequence": "MNGSAAGSDEGWHPESVLIPLAYLLIFLVGTVGNCLVLAVLLRNGQVKNTTNLFILNLGVADLCFILFCVPFQATIYTLEGWVFGSFLCKAVHFFIYLTMYASSFTLATVSLDRYLAIRYPLHSRELRTPRNALVAICFIWALSIIFSSPYLSYYQQLQLANLTVCHPVWATSQRKVMDLCTFIFSYIIPVLILSLTYTRTIRYLWRSVDPLQEMSESKKAKRKVTRMIVIVAVLFCLCWLPHHLVILCFWFGYFPLNHTTYVLRIVSHLISYANSCVNPIVYALVSKHFRKGFKKIFICLLHKKAANKVHVAQGTNTVSMLEAELSEVTRLSDAGPGCSSVRCKAQPWGEAALGGRQQRADGSFITFDVT", "length": 371, "header": "tr|A0A8V1ALV0-1|A0A8V1ALV0_CHICK Isoform 1 of Galanin receptor 2 OS=Gallus gallus OX=9031 GN=GALR2 PE=3 SV=1 CANONICAL=A0A8V1ALV0-1" }, "locus": { "chromosome": "18", "start_pos": 5162070, "end_pos": 5160045, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071872.1", "url": "https://www.ensembl.org/id/ENSGALT00010071872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044562.1", "url": "https://www.ensembl.org/id/ENSGALP00010044562.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification and characterization of the chicken galanin receptor GalR2 and a novel GalR2-like receptor (GalR2-L).", "journal": "General and comparative endocrinology", "date": "2012-11-01", "authors": "Ho John Chi Wang, Jacobs Tim, Wang Yajun, Leung Frederick C", "evidence": [ { "database": "RefSeq", "id": "NP_001121535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121535" } ], "reference": [ { "type": "PubMed", "id": "22982974", "url": "https://glygen.org/publication/PubMed/22982974" } ] } ], "pathway": [ { "id": "gga:770030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770030", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R332-1", "protein_name": "Galanin receptor 2a", "gene_name": "galr2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNASQQIHVFSSHWKVESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQMDLDGTTVCIPAWSVHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWFGHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGCAFRNRVVNRIHTVQPAQTVSLMEAASSEGSNHCDGSTRGRLWSKSSKKMMTSAFMTFNVT", "length": 363 }, "evidence": [ { "id": "A0A8V1ALV0", "url": "https://omabrowser.org/oma/group/A0A8V1ALV0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HTW8-1", "protein_name": "Galanin receptor type 2", "gene_name": "Galr2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNGSGGPAAEDTSREGGSGGWQPEAVLVPLLFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYSQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVAAGSGSQRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLCRAPRRRASGRVCVVAPGNHSGSVLERESTDLTHVSEAAGPLVPAPALPNCIASSRALNPVC", "length": 373 }, "evidence": [ { "id": "A0A8V1ALV0", "url": "https://omabrowser.org/oma/group/A0A8V1ALV0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08726-1", "protein_name": "Galanin receptor type 2", "gene_name": "Galr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTLDPAC", "length": 372 }, "evidence": [ { "id": "A0A8V1ALV0", "url": "https://omabrowser.org/oma/group/A0A8V1ALV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43603-1", "protein_name": "Galanin receptor type 2", "gene_name": "GALR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA", "length": 387 }, "evidence": [ { "id": "A0A8V1ALV0", "url": "https://omabrowser.org/oma/group/A0A8V1ALV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88854-1", "protein_name": "Galanin receptor type 2", "gene_name": "Galr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGSDSQGAEDSSQEGGGGWQPEAVLVPLFFALIFLVGAVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYSQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLHYLWRTVDPVAAGSGSQRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRRAPRRASGRVCILAPGNHSGGMLEPESTDLTQVSEAAGPLVPAPALPNCTTLSRTLDPAC", "length": 371 }, "evidence": [ { "id": "A0A8V1ALV0", "url": "https://omabrowser.org/oma/group/A0A8V1ALV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "pmid": "" }, { "name": "9+0 non-motile cilium", "id": "GO:0097731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "pmid": "" }, { "name": "galanin-activated signaling pathway", "id": "GO:0090663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090663", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "pmid": "" }, { "name": "galanin receptor activity", "id": "GO:0004966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 283, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1BSA8-1", "uniprot_ac": "E1BSA8", "uniprot_id": "E1BSA8_CHICK", "mass": { "chemical_mass": 48955.0, "monoisotopic_mass": 48955.0 }, "refseq": { "ac": "XP_004946169", "name": "UNC93-like protein MFSD11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946169" }, "gene_names": [ { "name": "MFSD11", "type": "recommended", "evidence": [ { "id": "E1BSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSA8" } ] }, { "name": "MFSD11", "type": "synonym", "evidence": [ { "id": "XP_004946169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946169" } ] } ], "protein_names": [ { "name": "UNC93-like protein MFSD11", "type": "recommended", "evidence": [ { "id": "E1BSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSA8/entry#names_and_taxonomy" } ] }, { "name": "Major facilitator superfamily domain-containing protein 11", "type": "synonym", "evidence": [ { "id": "E1BSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSA8/entry#names_and_taxonomy" } ] }, { "name": "UNC93-like protein MFSD11", "type": "synonym", "evidence": [ { "id": "XP_004946169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946169" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946169" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSA8", "url": "https://www.uniprot.org/uniprotkb/E1BSA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD11", "url": "https://www.uniprot.org/uniprotkb/E1BSA8", "locus": { "chromosome": "18", "start_pos": 4848701, "end_pos": 4866574, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029369", "url": "https://www.ensembl.org/id/ENSGALG00010029369" } ] } } ], "crossref": [ { "id": "E1BSA8", "url": "https://alphafold.ebi.ac.uk/entry/E1BSA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001777", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001777", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417352", "url": "https://www.ncbi.nlm.nih.gov/gene/417352", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417352", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417352", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFQDKTH", "url": "https://omabrowser.org/oma/group/QFQDKTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ACJ9", "url": "https://www.orthodb.org/?gene=A0A8V1ACJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALV7", "url": "https://www.orthodb.org/?gene=A0A8V1ALV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSA8", "url": "https://www.orthodb.org/?gene=E1BSA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23294:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23294:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004946169", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946169", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ACJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ACJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSA8", "url": "https://www.uniprot.org/uniprotkb/E1BSA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSA8-1", "url": "https://www.uniprot.org/uniprotkb/E1BSA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPDSKKLFNVLILGISFMFIFTAFQTCGNIAQTVITNLNSTDFHGSGYTSMSIIYGVFSASNLISPSVVALVGPQLSMFISGIFYSLYIAVFIQPSTWSFYTASVFIGIAAAVLWTAQGNCLTINSDENTIGRNSGVFWALLQSSLFFGNLYIYFAWQGKTYISESDRRTVFIALTVISLVGTVLFFLIRKQEDTKAPGEEDSTNEIHGDSSSAQNKLMRAVDAFKRSIKLSFTKEILLLSVTTAYTGLELTFFSGVYGTCIGAVNRFGTEEKSLIGLSGIFIGVGEILGGGIFGLLSKKSRFGRNPIVMLGIAVHFIAFYLIFVNMPSNAPVAPMEGTDDIAYMIPSKEVAIFCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAAVAYFYSNYFLLQWQLLIMVVVGFFGTITFFAVEWKAAALLARGSDYSSI", "length": 448, "header": "tr|E1BSA8-1|E1BSA8_CHICK Isoform 1 of UNC93-like protein MFSD11 OS=Gallus gallus OX=9031 GN=MFSD11 PE=3 SV=1 CANONICAL=E1BSA8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ACJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSA8/entry#A0A8V1ACJ9-1", "sequence": { "sequence": "MSPDSKKLFNVLILGISFMFIFTAFQTCGNIAQTVITNLNSTDFHGSGYTSMSIIYGVFSASNLISPSVVALVGPQLSMFISGIFYSLYIAVFIQPSTWSFYTASVFIGIAAAVLWTAQGNCLTINSDENTIGRNSGVFWALLQSSLFFGNLYIYFAWQGKTYISESDRRTVFIALTVISLVGTVLFFLIRKQEDTKAPGEEDSTNEIHGDSSSAQNKLMRAVDAFKRSIKLSFTKEILLLSVTTAYTGLELTFFSGVYGTCIGAVNRFGTEEKSLIGLSGIFIGVGEILGGGIFGLLSKKSRFGRNPIVMLGIAVHFIAFYLIFVNMPSNAPVAPMEGTDDIAYMIPSKEVAIFCSFLLGLGDSCFNTQLLSILGFLLQWQLLIMVVVGFFGTITFFAVEWKAAALLARGSDYSSI", "length": 417, "header": "tr|A0A8V1ACJ9-1|A0A8V1ACJ9_CHICK Computationally mapped isoform of UNC93-like protein MFSD11 OS=Gallus gallus OX=9031 GN=MFSD11 PE=3 SV=1 CANONICAL=E1BSA8-1" }, "locus": { "chromosome": "18", "start_pos": 4864253, "end_pos": 4851521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071028.1", "url": "https://www.ensembl.org/id/ENSGALT00010071028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043719.1", "url": "https://www.ensembl.org/id/ENSGALP00010043719.1" } ] } }, { "isoform_ac": "A0A8V1ALV7-1", "url": "https://www.uniprot.org/uniprotkb/E1BSA8/entry#A0A8V1ALV7-1", "sequence": { "sequence": "MSPDSKKLFNVLILGISFMFIFTAFQTCGNIAQTVITNLNSTDFHGSGYTSMSIIYGVFSASNLISPSVVALVGPQLSMFISGIFYSLYIAVFIQPSTWSFYTASVFIGIAAAVLWTAQGNCLTINSDENTIGRNSGVFWALLQSSLFFGNLYIYFAWQGKTYISESDRRTVFIALTVISLVGTVLFFLIRKQEDTKAPGEEDSTNEIHGDSSSAQNKLMRAVDAFKRSIKLSFTKEILLLSVTTAYTGLELTFFSGVYGTCIGAVNRFGTEEKSLIGLSGIFIGVGEILGGGIFGLLSKKSRFGRNPIVMLGIAVHFIAFYLIFVNMPSNAPVAPMEGTDDIAYMIPSKEVAIFCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAAVAYFYSNYFLLHGTAAVTFSG", "length": 420, "header": "tr|A0A8V1ALV7-1|E1BSA8_CHICK Computationally mapped isoform of UNC93-like protein MFSD11 OS=Gallus gallus OX=9031 GN=MFSD11 PE=3 SV=1 CANONICAL=E1BSA8-1" }, "locus": { "chromosome": "18", "start_pos": 4864253, "end_pos": 4850840, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071026.1", "url": "https://www.ensembl.org/id/ENSGALT00010071026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043717.1", "url": "https://www.ensembl.org/id/ENSGALP00010043717.1" } ] } }, { "isoform_ac": "E1BSA8-1", "url": "https://www.uniprot.org/uniprotkb/E1BSA8/entry#E1BSA8-1", "sequence": { "sequence": "MSPDSKKLFNVLILGISFMFIFTAFQTCGNIAQTVITNLNSTDFHGSGYTSMSIIYGVFSASNLISPSVVALVGPQLSMFISGIFYSLYIAVFIQPSTWSFYTASVFIGIAAAVLWTAQGNCLTINSDENTIGRNSGVFWALLQSSLFFGNLYIYFAWQGKTYISESDRRTVFIALTVISLVGTVLFFLIRKQEDTKAPGEEDSTNEIHGDSSSAQNKLMRAVDAFKRSIKLSFTKEILLLSVTTAYTGLELTFFSGVYGTCIGAVNRFGTEEKSLIGLSGIFIGVGEILGGGIFGLLSKKSRFGRNPIVMLGIAVHFIAFYLIFVNMPSNAPVAPMEGTDDIAYMIPSKEVAIFCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAAVAYFYSNYFLLQWQLLIMVVVGFFGTITFFAVEWKAAALLARGSDYSSI", "length": 448, "header": "tr|E1BSA8-1|E1BSA8_CHICK Isoform 1 of UNC93-like protein MFSD11 OS=Gallus gallus OX=9031 GN=MFSD11 PE=3 SV=1 CANONICAL=E1BSA8-1" }, "locus": { "chromosome": "18", "start_pos": 4864253, "end_pos": 4851521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071030.1", "url": "https://www.ensembl.org/id/ENSGALT00010071030.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043721.1", "url": "https://www.ensembl.org/id/ENSGALP00010043721.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417352", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417352", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N2H3-1", "protein_name": "UNC93-like protein MFSD11", "gene_name": "MFSD11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSPESKKLFNIIILGIAFMFIFTAFQTCGNVAQTVIRSLNSTDFHGSGYTSMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGRNSGIFWALLQFSLFFGNLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLGEDESSDDQDLDINESPQSNMTKAVDAFKKSLKLCVTKEMLLLSITTAYTGLELTFFSGVYGTCIGAINKFGTEEKSLIGLSGIFIGIGEILGGSLFGLLSKNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVEGTDSSAYIKPSKEIAIFCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAVFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTVSFFTVEWEAAAIVARGSDYRSI", "length": 449 }, "evidence": [ { "id": "E1BSA8", "url": "https://omabrowser.org/oma/group/E1BSA8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZEI8-1", "protein_name": "UNC93-like protein MFSD11", "gene_name": "Mfsd11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPESKKLFNIVILGVAFMFMFTAFQTCGNVAQTVIRSLNSTDFHGSGYTSLAIIYGVFSASNLITPSVVAIVGPQISMFVSGLFYSIYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGRNSGIFWALLQSSLFFGNLYIYFAWQGKTQISENDRRTVFIALTVISLVGTVLFFLIRKPDPENVLGEEDESCDDQDMEATESAQNNVTKAVDAFKKSLRLCVTKEMLLLSVTTAYTGLELTFFSGVYGTCIGAVNKFGTEEKSLIGLSGIFIGIGEILGGSLFGLLSKNSRFGRNPVVLLGTLVHFVAFYLIFLNMPGDAPIAPVEGTNSSAYIRPSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAVFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFAVEWDAAAIVARGSDYRSI", "length": 450 }, "evidence": [ { "id": "E1BSA8", "url": "https://omabrowser.org/oma/group/E1BSA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L5U8-1", "protein_name": "UNC93-like protein MFSD11", "gene_name": "MFSD11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSPESKKLFNIIILGIAFMFMFTAFQTCGNVAQTVIRSLNSTDFHGSGYTSMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGRNSGIFWALLQSSLFFGNLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLGEDESSDDQDLDVNESAQNNMTKAVDAFKKSLRLCVTKEMLLLSVTTAYTGVEMTFFSGVYGTCIGAINKFGTEEKSLIGLSGIFIGIGEILGGSLFGLLSKNTRFGRNPVVLLGVLVHFLAFYLIFLNMPGDAPIAPVEGTDSSAYIKPSKEVAIFCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAVFKFVQSICAAVAFFYSNYLLLHWQLLVMVLFGFFGTISFFTVEWEAAAIVARGSDYRSI", "length": 449 }, "evidence": [ { "id": "E1BSA8", "url": "https://omabrowser.org/oma/group/E1BSA8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43934-1", "protein_name": "UNC93-like protein MFSD11", "gene_name": "MFSD11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPESKKLFNIIILGVAFMFMFTAFQTCGNVAQTVIRSLNRTDFHGSGYTSMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHSIGRNSGIFWALLQSSLFFGNLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLGEDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVTKEMLLLSITTAYTGLELTFFSGVYGTCIGATNKFGAEEKSLIGLSGIFIGIGEILGGSLFGLLSKNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVKGTDSSAYIKSSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFTVEWEAAAFVARGSDYRSI", "length": 449 }, "evidence": [ { "id": "E1BSA8", "url": "https://omabrowser.org/oma/group/E1BSA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54E68-1", "protein_name": "UNC93-like protein MFSD11", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNKEDLLQTPLLNDHHHQEENDYYSHSKSIQNKNNNKINIIILGLCFCILFSAFSPTQILQTTINQNLGYYTLAVLYSSLSISNFISPFIVSKFGEKISLIIGTLSYAIYIGSNIYVTQPSLYISSILVGFGGAILWNAQGSLIIKYSTEETIGANTGLFFALFQTDQIIGNIGSATLINKAGLSNSILFTIFMGISLMPIIGFLFLKCPITPKIKKTIKSINIQDEETKGNQENHDDDDLSIKNIFKSIIILFKDKPIQLLIPSLLYSGISQTFFFGVFPSLIGVEWVGYVMSVFGFFDALSSFILGKLSFKIGRKILILISTISSIIGTVLIILVNQSKIIYFSINNNNNYGEYKILCYFIGSALLGFSDAGFNTQLYSLLGVLYPTNGEAAVGVFKFVQSTATAVAFIYGPYASLFENVFVLDCLVIISCVFFIFADNFSKSV", "length": 447 }, "evidence": [ { "id": "E1BSA8", "url": "https://omabrowser.org/oma/group/E1BSA8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BJ51-1", "protein_name": "UNC93-like protein MFSD11", "gene_name": "Mfsd11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPESKKLFNIVILGVAFMFMFTAFQTCGNVAQTVIRSLNSTDFHGSGYTSLAIIYGVFSASNLITPSVVAIVGPQISMFVSGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGRNSGIFWALLQSSLFFGNLYIYFAWQGKTQISEHDRRTVFIALTVISLVGTVLFFLIRKPDPENVLGEEESCDDQDMEATESAQNNVTKAVDAFKKSLRLCVTREMLLLSVTTAYTGLELTFFSGVYGTCIGAVNKFGTEEKSLIGLSGIFIGIGEILGGSLFGLLSKNSRFGRNPVVLLGTLVHFVAFYLIFLNMPGDAPIAPVEGTNSIAYIRPSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAVFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFAVEWDAAAIVARGSDYRSI", "length": 449 }, "evidence": [ { "id": "E1BSA8", "url": "https://omabrowser.org/oma/group/E1BSA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VG64-1", "protein_name": "UNC93-like protein MFSD11", "gene_name": "Dmel\\CG18549", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFKFLMILILGFGFMFVFTAFQTMCNIEKTILDSISQEDDTFKGEGYTSLAIIYLFFSLSNWLAPSFISFTGPRVAMVVGALTYTAFMITFMFPSTVLLYVGSAVLGLGASITWTGQGTYLARCSESSTISRNSGVFWALLQCSMFIGNLFVYYQFQDKTRIDKETRNLVIGVLTVIAVLGIVFLAALRFMADNAEHDNELEQKHTGCGQAIYALKSAGQLFLTKKMLLLSLAFFYTGLELSFFSGVFGSAIGFTTKIAETPKEIVGLVGICIGAGEVFGGGLFGILGNKTTRYGRDPIVIAGYVMHMAAFFMTFINLPNSAPFKDTTDISYLDPPRASIALVCAFLLGLGDACFNTQIYSMLGGEYVNNAVGAFALFKFTQSVAAAISFFYSSHFGLYVQLGILVVMGTIGTIAFVFVEWGFKRQHREQEALEK", "length": 436 }, "evidence": [ { "id": "E1BSA8", "url": "https://omabrowser.org/oma/group/E1BSA8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BSA8", "url": "https://www.uniprot.org/uniprotkb/E1BSA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSA8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 448, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSA8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSA8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALV9-1", "uniprot_ac": "A0A8V1ALV9", "uniprot_id": "A0A8V1ALV9_CHICK", "mass": { "chemical_mass": 65387.0, "monoisotopic_mass": 65387.0 }, "refseq": {}, "gene_names": [ { "name": "PIP5K1A", "type": "recommended", "evidence": [ { "id": "A0A8V1ALV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ] } ], "protein_names": [ { "name": "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha", "type": "synonym", "evidence": [ { "id": "A0A8V1ALV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIP5K1A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9", "locus": { "chromosome": "25", "start_pos": 2658934, "end_pos": 2641309, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028871", "url": "https://www.ensembl.org/id/ENSGALG00010028871" } ] } } ], "crossref": [ { "id": "A0A8V1ALV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429983", "url": "https://www.ncbi.nlm.nih.gov/gene/429983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429983", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429983", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIFYADD", "url": "https://omabrowser.org/oma/group/CIFYADD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AAF3", "url": "https://www.orthodb.org/?gene=A0A8V1AAF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFT3", "url": "https://www.orthodb.org/?gene=A0A8V1AFT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALV9", "url": "https://www.orthodb.org/?gene=A0A8V1ALV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23086:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23086:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AAF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AAF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AAF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGPESGGSSGSSGGLGDFSFLCCSVMSFRRGPSAFKKSLTPEMPGSSGQPGSQTIKKGHRGVDSTGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHLKYDLKGSTYKRRASQKEREKVFPTYKDLDFMQDIPDGLFLDSDMYNALCKTLQRDCLVLQSFKIMDYSLLVAIHNMDLAQREHVMADRTSQADTRRPAAQKALYSTAMESIQGEARRGGTIETDDQMGGIPARNAKGERLLLYVGIIDVLQSYRFVKKLEHSWKALVHDGDTVSVHRPSFYAERFQRFMCNTVFKKIPLKPSPSKKSRSGTAVPRRSCQGGVPSQLHVLCETKAQVTTEADVEQGSHLGRPDLLPRTLPVDEANSDSVATTLSTSSLGSGGLHSPANRSVGVQVHKADSSAKDFARTAAFLSSSPGLSVPEPSSELREQLEELQETEISF", "length": 592, "header": "tr|A0A8V1ALV9-1|A0A8V1ALV9_CHICK Isoform 1 of Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha OS=Gallus gallus OX=9031 GN=PIP5K1A PE=4 SV=1 CANONICAL=A0A8V1ALV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AAF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9/entry#A0A8V1AAF3-1", "sequence": { "sequence": "MPGSSGQPGSQTIKKGHRGVDSTGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHLKYDLKGSTYKRRASQKEREKVFPTYKDLDFMQDIPDGLFLDSDMYNALCKTLQRDCLVLQSFKIMDYSLLVAIHNMDLAQREHVMADRTSQADTRRPAAQKALYSTAMESIQGEARRGGTIETDDQMGGIPARNAKGERLLLYVGIIDVLQSYRFVKKLEHSWKALVHDGDTVSVHRPSFYAERFQRFMCNTVFKKIPLKPSPSKKSRSGTAVPRRSCQGGVPSQLHVLCETKAQVTTEADVEQGSHLGRPDLLPRTLPVDEANSDSVATTLSTSSLGSGGLHSPANRQFSPMGGILRTVSSLQRLESALESSSALSTGEFLTSALPAQRDAVVPCGDTKGCCVQRSPGTSWCRGGRFTVPFRSRLSPTSHLEWVLIFF", "length": 586, "header": "tr|A0A8V1AAF3-1|A0A8V1AAF3_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha OS=Gallus gallus OX=9031 GN=PIP5K1A PE=4 SV=1 CANONICAL=A0A8V1ALV9-1" }, "locus": { "chromosome": "25", "start_pos": 2657465, "end_pos": 2647212, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069833.1", "url": "https://www.ensembl.org/id/ENSGALT00010069833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042959.1", "url": "https://www.ensembl.org/id/ENSGALP00010042959.1" } ] } }, { "isoform_ac": "A0A8V1AFT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9/entry#A0A8V1AFT3-1", "sequence": { "sequence": "MAAAGPESGGSSGSSGGLGDFSFLCCSVMSFRRGPSAFKKSLTPEMPGSSGQPGSQTIKKGHRGVDSTGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHLKYDLKGSTYKRRASQKEREKVFPTYKDLDFMQDIPDGLFLDSDMYNALCKTLQRDCLVLQSFKIMDYSLLVAIHNMDLAQREHVMADRTSQADTRRPAAQKALYSTAMESIQGEARRGGTIETDDQMGGIPARNAKGERLLLYVGIIDVLQSYRFVKKLEHSWKALVHDGDTVSVHRPSFYAERFQRFMCNTVFKKIPLKPSPSKKSRSGTAVPRRSCQGGVPSQLHVLCETKAQVTTEADVEQGSHLGRPDLLPRTLPVDEANSDSVATTLSTSSLGSGGLHSPANSSSPGLSVPEPSSELREQLEELQETEISF", "length": 568, "header": "tr|A0A8V1AFT3-1|A0A8V1AFT3_CHICK Computationally mapped isoform of Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha OS=Gallus gallus OX=9031 GN=PIP5K1A PE=4 SV=1 CANONICAL=A0A8V1ALV9-1" }, "locus": { "chromosome": "25", "start_pos": 2656091, "end_pos": 2641508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069835.1", "url": "https://www.ensembl.org/id/ENSGALT00010069835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042961.1", "url": "https://www.ensembl.org/id/ENSGALP00010042961.1" } ] } }, { "isoform_ac": "A0A8V1ALV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9/entry#A0A8V1ALV9-1", "sequence": { "sequence": "MAAAGPESGGSSGSSGGLGDFSFLCCSVMSFRRGPSAFKKSLTPEMPGSSGQPGSQTIKKGHRGVDSTGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHLKYDLKGSTYKRRASQKEREKVFPTYKDLDFMQDIPDGLFLDSDMYNALCKTLQRDCLVLQSFKIMDYSLLVAIHNMDLAQREHVMADRTSQADTRRPAAQKALYSTAMESIQGEARRGGTIETDDQMGGIPARNAKGERLLLYVGIIDVLQSYRFVKKLEHSWKALVHDGDTVSVHRPSFYAERFQRFMCNTVFKKIPLKPSPSKKSRSGTAVPRRSCQGGVPSQLHVLCETKAQVTTEADVEQGSHLGRPDLLPRTLPVDEANSDSVATTLSTSSLGSGGLHSPANRSVGVQVHKADSSAKDFARTAAFLSSSPGLSVPEPSSELREQLEELQETEISF", "length": 592, "header": "tr|A0A8V1ALV9-1|A0A8V1ALV9_CHICK Isoform 1 of Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha OS=Gallus gallus OX=9031 GN=PIP5K1A PE=4 SV=1 CANONICAL=A0A8V1ALV9-1" }, "locus": { "chromosome": "25", "start_pos": 2656091, "end_pos": 2641508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069834.1", "url": "https://www.ensembl.org/id/ENSGALT00010069834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042960.1", "url": "https://www.ensembl.org/id/ENSGALP00010042960.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429983", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-GGA-6811558", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "resource": "Reactome", "description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4F0-1", "protein_name": "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha", "gene_name": "PIP5K1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASASSGSSAVGSSPVDSGVPPCTSSSGFNFLCCGVNRKRASGIKRPMASEVLYASGMPMKKIGHRGVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTLKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLVSIHNIDHAQREPLSNEAQYPADTRRPAPQKALYSTAMESIQGEARRGGTVETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSPSKKFRSGSSFSRRAGPSGNSCITYQPSISGEPKAQVTTKAEVEPGVHLGRPDVLPQTPPLEKISEVSTIPDPYFSPVIGETLQMLTTSSTILEKPEVTDFTESEFIH", "length": 565 }, "evidence": [ { "id": "A0A8V1ALV9", "url": "https://omabrowser.org/oma/group/A0A8V1ALV9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZSI8-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha", "gene_name": "Pip5k1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASASSGPAAAGFSPLDSGVPAGTAASGIKRGTVSEGPYASLMPVKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPMNSETQYSIDTRRPAPQKALYSTAMESIQGEARRGGTVETEDHMGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSPTKKFRSGPSFSRRSGPSGNSCTPSQPTASGEHKAQVTTKAEVEPDIHLGRPDVLPQTPPLEEISEGSPVPGPSFSPAVGQPLQILNLSSTLEKLDVAESELTH", "length": 546 }, "evidence": [ { "id": "A0A8V1ALV9", "url": "https://omabrowser.org/oma/group/A0A8V1ALV9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70182-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha", "gene_name": "Pip5k1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASASSGPAAAGFSSLDAGAPAGTAAASGIKRATVSEGPSASVMPVKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQREPTSNDTQYSADTRRPAPQKALYSTAMESIQGEARRGGTVETEDHMGGIPARNNKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSPTKKFRSGPSFSRRSGPSGNSCTSQLMASGEHRAQVTTKAEVEPDVHLGRPDVLPQTPPLEEISEGSPVPGPSFSPVVGQPLQILNLSSTLEKLDVAESEFTH", "length": 546 }, "evidence": [ { "id": "A0A8V1ALV9", "url": "https://omabrowser.org/oma/group/A0A8V1ALV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99755-1", "protein_name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha", "gene_name": "PIP5K1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASASSGPSSSVGFSSFDPAVPSCTLSSAASGIKRPMASEVLEARQDSYISLVPYASGMPIKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDYSLLMSIHNIDHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDHMGGIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHDGDTVSVHRPGFYAERFQRFMCNTVFKKIPLKPSPSKKFRSGSSFSRRAGSSGNSCITYQPSVSGEHKAQVTTKAEVEPGVHLGRPDVLPQTPPLEEISEGSPIPDPSFSPLVGETLQMLTTSTTLEKLEVAESEFTH", "length": 562 }, "evidence": [ { "id": "A0A8V1ALV9", "url": "https://omabrowser.org/oma/group/A0A8V1ALV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 5-kinase activity", "id": "GO:0016308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "phosphatidylinositol kinase activity", "id": "GO:0052742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "focal adhesion assembly", "id": "GO:0048041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048041", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "ruffle assembly", "id": "GO:0097178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ALV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALV9" }, { "id": "PS51455", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51455" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIPK", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 445, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 539, "end_pos": 541 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BVD2-1", "uniprot_ac": "E1BVD2", "uniprot_id": "E1BVD2_CHICK", "mass": { "chemical_mass": 138530.0, "monoisotopic_mass": 138530.0 }, "refseq": { "ac": "XP_415729", "name": "autism susceptibility gene 2 protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415729" }, "gene_names": [ { "name": "AUTS2", "type": "recommended", "evidence": [ { "id": "E1BVD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVD2" } ] }, { "name": "AUTS2", "type": "synonym", "evidence": [ { "id": "XP_415729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415729" } ] } ], "protein_names": [ { "name": "Activator of transcription and developmental regulator AUTS2", "type": "synonym", "evidence": [ { "id": "E1BVD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVD2/entry#names_and_taxonomy" } ] }, { "name": "autism susceptibility gene 2 protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_415729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415729" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_415729.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415729" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BVD2", "url": "https://www.uniprot.org/uniprotkb/E1BVD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AUTS2", "url": "https://www.uniprot.org/uniprotkb/E1BVD2", "locus": { "chromosome": "19", "start_pos": 1848248, "end_pos": 2509806, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029371", "url": "https://www.ensembl.org/id/ENSGALG00010029371" } ] } } ], "crossref": [ { "id": "E1BVD2", "url": "https://alphafold.ebi.ac.uk/entry/E1BVD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001153", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001153", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417481", "url": "https://www.ncbi.nlm.nih.gov/gene/417481", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALW1", "url": "https://www.orthodb.org/?gene=A0A8V1ALW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVD2", "url": "https://www.orthodb.org/?gene=E1BVD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14429", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14429", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14429:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14429:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415729", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVD2", "url": "https://www.uniprot.org/uniprotkb/E1BVD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BVD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGPARCNGLRKKRRSRSQRDRERRAQGGRRGAAAGGAPGPGAAPALSSSGSEKEDNGPPPPSRPRPPRRKRRESSSAEEDIIDGFAMSSFVTFEALEKDVALKPQERVEKRQNPLAKKKREALTNGLSYLPKKNRLHHHQYSSDRENDRNLCQHLGKRKKLLKGLRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNAVTNKDKELGVSALAENADPGARGPAVPKISGLERSQEKSQDSSKDPILEPVVPKDPCPQVAQPLAQPQLEPQPEVPCPSPALAPRPEAPAPPAPPPAAQLPPAPEEPTRPPAPQPPVQHPPRPQSPVQPAHPNLPAVQPHPAAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQAPPPHISHHPSASPFPLSLPSHSPLHTFTPTLQPPAHPHHPNMFAPPTALPPPPPLTSGTLQVPGHPAGSTYSEQDLLRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSTASGAHPAGTPFGPPPHHSNFLNPAAHLEPFNRPASFSGLTAVGSNAFGGLGNPTVTPNSMFGHKDGPSMQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSSSAAAHDRDRDVDKRDSSVSKDDKERESIEKRHSSHPSPAPIHPVNSLGHNRSSNEQIRSHLNPEVREKEKPKERERDHSESRKEINVEEHKVKDNYISEKESLSHESRVVEESKQMSRVPSPYARPPVVESNRPNSTSNREAERKNEPAYDNPKKSNEVKVKEERKEDHDAQHEGPQTHRSSDQPPPISTSNVHPSPLVSMPMTVGVTGIHHINSISGLDRTRMMTPFMGISPIPGGERFPYPSFHWDPMRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHPLSVDPRREHERGNHLDDRERLHMLREDYEHARLHSVHPAALDGHLPHPSLITPGLPSMHYPRVSPPTGHQNGILNKTPPTAALSAPPPLISTLGPRPGSPRRTTPLSAEMRERPPSHTLKDIEAR", "length": 1251, "header": "tr|E1BVD2-1|E1BVD2_CHICK Isoform 1 of Activator of transcription and developmental regulator AUTS2 OS=Gallus gallus OX=9031 GN=AUTS2 PE=4 SV=3 CANONICAL=E1BVD2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALW1-1", "url": "https://www.uniprot.org/uniprotkb/E1BVD2/entry#A0A8V1ALW1-1", "sequence": { "sequence": "MSSFVTFEALEKDVALKPQERVEKRQNPLAKKKREALTNGLSYLPKKNRLHHHQYSSDRENDRNLCQHLGKRKKLLKGLRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNAVTNKDKELGVSALAENADPGARGPAVPKISGLERSQEKSQDSSKDPILEPVVPKDPCPQVAQPLAQPQLEPQPEVPCPSPALAPRPEAPAPPAPPPAAQLPPAPEEPTRPPAPQPPVQHPPRPQSPVQPAHPNLPAVQPHPAAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQAPPPHISHHPSASPFPLSLPSHSPLHTFTPTLQPPAHPHHPNMFAPPTALPPPPPLTSGTLQVPGHPAGSTYSEQDLLRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMVRTPGRNLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSTASGAHPAGTPFGPPPHHSNFLNPAAHLEPFNRPASFSGLTAVGSNAFGGLGNPTVTPNSMFGHKDGPSMQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSSSAAAHDRDRDVDKRDSSVSKDDKERESIEKRHSSHPSPAPIHPVNSLGHNRSSNEQIRSHLNPEVREKEKPKERERDHSESRKEINVEEHKVKDNYISEKESLSHESRVVEESKQMSRVPSPYARPPVVESNRPNSTSNREAERKNEPAYDNPKKSNEVKVKEERKEDHDAQHEGPQTHRSSDQPPPISTSNVHPSPLVSMPMTVGVTGIHHINSISGLDRTRMMTPFMGISPIPGGERFPYPSFHWDPMRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHPLSVDPRREHERGNHLDDRERLHMLREDYEHARLHSVHPAALDGHLPHPSLITPGLPSMHYPRVSPPTGHQNGILNKTPPTAALSAPPPLISTLGPRPGSPRRTTPLSAEMRERPPSHTLKDIEAR", "length": 1156, "header": "tr|A0A8V1ALW1-1|E1BVD2_CHICK Computationally mapped isoform of Activator of transcription and developmental regulator AUTS2 OS=Gallus gallus OX=9031 GN=AUTS2 PE=4 SV=1 CANONICAL=E1BVD2-1" }, "locus": { "chromosome": "19", "start_pos": 2509346, "end_pos": 1849701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071032.1", "url": "https://www.ensembl.org/id/ENSGALT00010071032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043723.1", "url": "https://www.ensembl.org/id/ENSGALP00010043723.1" } ] } }, { "isoform_ac": "E1BVD2-1", "url": "https://www.uniprot.org/uniprotkb/E1BVD2/entry#E1BVD2-1", "sequence": { "sequence": "MDGPARCNGLRKKRRSRSQRDRERRAQGGRRGAAAGGAPGPGAAPALSSSGSEKEDNGPPPPSRPRPPRRKRRESSSAEEDIIDGFAMSSFVTFEALEKDVALKPQERVEKRQNPLAKKKREALTNGLSYLPKKNRLHHHQYSSDRENDRNLCQHLGKRKKLLKGLRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNAVTNKDKELGVSALAENADPGARGPAVPKISGLERSQEKSQDSSKDPILEPVVPKDPCPQVAQPLAQPQLEPQPEVPCPSPALAPRPEAPAPPAPPPAAQLPPAPEEPTRPPAPQPPVQHPPRPQSPVQPAHPNLPAVQPHPAAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQAPPPHISHHPSASPFPLSLPSHSPLHTFTPTLQPPAHPHHPNMFAPPTALPPPPPLTSGTLQVPGHPAGSTYSEQDLLRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSTASGAHPAGTPFGPPPHHSNFLNPAAHLEPFNRPASFSGLTAVGSNAFGGLGNPTVTPNSMFGHKDGPSMQSFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSSSAAAHDRDRDVDKRDSSVSKDDKERESIEKRHSSHPSPAPIHPVNSLGHNRSSNEQIRSHLNPEVREKEKPKERERDHSESRKEINVEEHKVKDNYISEKESLSHESRVVEESKQMSRVPSPYARPPVVESNRPNSTSNREAERKNEPAYDNPKKSNEVKVKEERKEDHDAQHEGPQTHRSSDQPPPISTSNVHPSPLVSMPMTVGVTGIHHINSISGLDRTRMMTPFMGISPIPGGERFPYPSFHWDPMRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYNHHHHHHHPLSVDPRREHERGNHLDDRERLHMLREDYEHARLHSVHPAALDGHLPHPSLITPGLPSMHYPRVSPPTGHQNGILNKTPPTAALSAPPPLISTLGPRPGSPRRTTPLSAEMRERPPSHTLKDIEAR", "length": 1251, "header": "tr|E1BVD2-1|E1BVD2_CHICK Isoform 1 of Activator of transcription and developmental regulator AUTS2 OS=Gallus gallus OX=9031 GN=AUTS2 PE=4 SV=3 CANONICAL=E1BVD2-1" }, "locus": { "chromosome": "19", "start_pos": 2509607, "end_pos": 1849701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071033.1", "url": "https://www.ensembl.org/id/ENSGALT00010071033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043724.1", "url": "https://www.ensembl.org/id/ENSGALP00010043724.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 553, "start_aa": "Thr", "end_pos": 553, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr553", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 800, "start_aa": "Thr", "end_pos": 800, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr800", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E1BVD2", "url": "https://www.uniprot.org/uniprotkb/E1BVD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BVD2", "url": "https://www.uniprot.org/uniprotkb/E1BVD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1201, "end_pos": 1203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 864, "end_pos": 866, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BVD2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1251, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BVD2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BVD2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 553, 800 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1201, "end_pos": 1203 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 864, "end_pos": 866 }, { "start_pos": 949, "end_pos": 951 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALY4-1", "uniprot_ac": "A0A8V1ALY4", "uniprot_id": "A0A8V1ALY4_CHICK", "mass": { "chemical_mass": 19438.0, "monoisotopic_mass": 19438.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ALY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY4", "locus": {} } ], "crossref": [ { "id": "A0A8V1ALY4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALY4", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1ALY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEKARLTRGGRLTAARRSARLWQRCSERAALPAAVSPLPPLLPQKQNARRASSPARARPSLRCTSSPSTTARHQETAVRAGTRPAMRTPRLPPSAEAEDPRPGPRPGPRRPQTAPGRRTLDNVAVDGGPELLAGRPVPVLPVDDPHLLEEGGLAALPRAQQQDLDEALHSLPSRPAEKCT", "length": 181, "header": "tr|A0A8V1ALY4-1|A0A8V1ALY4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ALY4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALY4/entry#A0A8V1ALY4-1", "sequence": { "sequence": "MSEKARLTRGGRLTAARRSARLWQRCSERAALPAAVSPLPPLLPQKQNARRASSPARARPSLRCTSSPSTTARHQETAVRAGTRPAMRTPRLPPSAEAEDPRPGPRPGPRRPQTAPGRRTLDNVAVDGGPELLAGRPVPVLPVDDPHLLEEGGLAALPRAQQQDLDEALHSLPSRPAEKCT", "length": 181, "header": "tr|A0A8V1ALY4-1|A0A8V1ALY4_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ALY4-1" }, "locus": { "chromosome": "18", "start_pos": 8387487, "end_pos": 8385631, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071062.1", "url": "https://www.ensembl.org/id/ENSGALT00010071062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043753.1", "url": "https://www.ensembl.org/id/ENSGALP00010043753.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ALZ0-1", "uniprot_ac": "A0A8V1ALZ0", "uniprot_id": "A0A8V1ALZ0_CHICK", "mass": { "chemical_mass": 29855.0, "monoisotopic_mass": 29855.0 }, "refseq": { "ac": "XP_015151333", "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151333" }, "gene_names": [ { "name": "PIGL", "type": "recommended", "evidence": [ { "id": "A0A8V1ALZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ] }, { "name": "PIGL", "type": "synonym", "evidence": [ { "id": "XP_015151333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151333" } ] } ], "protein_names": [ { "name": "N-acetylglucosaminylphosphatidylinositol deacetylase", "type": "recommended", "evidence": [ { "id": "A0A8V1ALZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0/entry#names_and_taxonomy" } ] }, { "name": "3.5.1.89", "type": "synonym", "evidence": [ { "id": "A0A8V1ALZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0/entry#names_and_taxonomy" } ] }, { "name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015151333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151333" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151333.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151333" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PIGL", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0", "locus": { "chromosome": "19", "start_pos": 7060455, "end_pos": 7007005, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029732", "url": "https://www.ensembl.org/id/ENSGALG00010029732" } ] } } ], "crossref": [ { "id": "A0A8V1ALZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ALZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "417600", "url": "https://www.ncbi.nlm.nih.gov/gene/417600", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417600", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417600", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YVLESVN", "url": "https://omabrowser.org/oma/group/YVLESVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALZ0", "url": "https://www.orthodb.org/?gene=A0A8V1ALZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12993:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12993:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162710", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAGPWGWGLVMLLLLLLAVLRCAARRQRSRSAAGSTVVSRDDGVSALLVTAHPDDEVMFFAPTLLCLGRAGARLAVLCCSAGNYYNQGEIRKKELEQSCCLLGVPASSVTVVDHRDLPDNPSIQWDTQLLASFVLKHIEANNINLVVTFDAGGVSGHANHISLYTALRYLHSERKLPEGCRVLVLESVNLLRKYISILDVFLSCLLPRDALFILTEEETEQARRAMQCHCSQLLWFRRIYMLFSRYVVINSLHLLEKTTLTTPGVKE", "length": 268, "header": "tr|A0A8V1ALZ0-1|A0A8V1ALZ0_CHICK Isoform 1 of N-acetylglucosaminylphosphatidylinositol deacetylase OS=Gallus gallus OX=9031 GN=PIGL PE=3 SV=1 CANONICAL=A0A8V1ALZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ALZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0/entry#A0A8V1ALZ0-1", "sequence": { "sequence": "MTAGPWGWGLVMLLLLLLAVLRCAARRQRSRSAAGSTVVSRDDGVSALLVTAHPDDEVMFFAPTLLCLGRAGARLAVLCCSAGNYYNQGEIRKKELEQSCCLLGVPASSVTVVDHRDLPDNPSIQWDTQLLASFVLKHIEANNINLVVTFDAGGVSGHANHISLYTALRYLHSERKLPEGCRVLVLESVNLLRKYISILDVFLSCLLPRDALFILTEEETEQARRAMQCHCSQLLWFRRIYMLFSRYVVINSLHLLEKTTLTTPGVKE", "length": 268, "header": "tr|A0A8V1ALZ0-1|A0A8V1ALZ0_CHICK Isoform 1 of N-acetylglucosaminylphosphatidylinositol deacetylase OS=Gallus gallus OX=9031 GN=PIGL PE=3 SV=1 CANONICAL=A0A8V1ALZ0-1" }, "locus": { "chromosome": "19", "start_pos": 7059684, "end_pos": 7007104, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071923.1", "url": "https://www.ensembl.org/id/ENSGALT00010071923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044613.1", "url": "https://www.ensembl.org/id/ENSGALP00010044613.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:417600", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417600", "resource": "KEGG Pathway" }, { "id": "R-GGA-162710", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162710", "resource": "Reactome", "description": "Synthesis of glycosylphosphatidylinositol (GPI)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RER5-1", "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "PIGL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEVAGVLLCLAAAVLAWGLLRVWDAWERMKSQEQAGLPGGGSRALLVTAHPDDEAMFFAPTILGLARLGHQLSLLCFSAGDYYNQGEIRKKELLQSCDVLGIPSSSVTIIDNRDFPDNPAVRWDPGRVADVLLRHIELNSIDLVVTFDAGGVSGHSNHVALYAAARTLCAEGKLPKGCKVLALQSVNRLRKYISLLDLPCSLLLARDALFVLTRQEVAQAQKAMSRHRSQLLWFRRLYVLFSRYLRINSLRRL", "length": 253 }, "evidence": [ { "id": "A0A8V1ALZ0", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6QQ24-1", "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "PIGL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVAAPLLCLAAAVLVWGVLWVWGSWERMTRPEQAGLPGGGSRTLLVTAHPDDEAMFFAPTILGLARLRHQLFLLCFSAGNYYNQGEIRKKELLQSCDVLGIPPSNVMIIENRDFPDDPDVRWDPDRAADVLLQHVEANGIKLVVTFDEGGVSGHSNHVALNAAVRTLQAEGKLPKGCSVLTLQSVNLLRKYLCLLDLPCSLLLARDALFVLTQREAAQAQRAMSCHRSQLLWFRRLYMLFSRYMRINSLNFL", "length": 253 }, "evidence": [ { "id": "A0A8V1ALZ0", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35790-1", "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "Pigl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVVGLLCVAVAVLTWGFLRVWNSAERMRSPEQAGLPGAGSRALVVIAHPDDEAMFFAPTILGLARLKQQVSLLCFSSGNYYNQGEIRKKELLQSCAVLGIPPSRVMIIDKREFPDDPEVQWDTEHVASTILQHIHANATDLVVTFDAEGVSGHSNHIALYKAVRALHSGGKLPEGCSVLTLQSVNVLRKYVFLLDLPWTLLSPQGVLFVLTSKEVAQAKKAMSCHRSQLLWFRHLYTVFSRYMSVNSLQLL", "length": 252 }, "evidence": [ { "id": "A0A8V1ALZ0", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23797-1", "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "GPI12", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKMLRRTKVNFSKLLYKITKLAIVLTILYIYFTPKIVSRNNASLQHIFPHKYGDYEINLVIAHPDDEVMFFSPIISQLNSYFPRTVPFNIICLSKGNAEGLGETRVRELNESAALLLHNERAVSVQVMDFQDGMDEIWDIDSITSSLSQKIDIKNHNLNQIIVTFDSYGVSNHINHKSCYAAVKKLVDDYAQPKTKRNEQPPHVTALYLRSYKNNIVLKYNSFIWEILKILYDLISPFRRIIQALPPNTAAEKDKLSLMNTHAQYVLAFATMLNAHESQVVWFRYGWWIFSRFVFVNEFDVYTY", "length": 304 }, "evidence": [ { "id": "A0A8V1ALZ0", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54C64-1", "protein_name": "Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "pigl", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNHLNNNEDNSTLIKKKVLFVIAHPDDECMFFTPTIQHYNFIGSEIFVACLSNGNAVGLGKIREKELIDSCIDMGINQENVFFDQTNNFQDGMNIIWDTDLVEKTILSFIKQTSADIVISFDECGISSHPNHISISNGLKQLMKNKSSSTTTTSTTSSSSSSSSLSNRTTNNLNKEIKAYKLETVNIIRKYIGIADIPLTKLLSYDENSTQTFISTQLFPPSSYSPMTKHKSQFVWFRYLFVFLSRYSFINTLIEIK", "length": 258 }, "evidence": [ { "id": "A0A8V1ALZ0", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5SX19-1", "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "Pigl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELVGFLCVAVAVLTWGFLRVWNSAERMRSPEQAGLPGAGSRALVVIAHPDDEAMFFAPTMLGLARLEQQVSLLCFSSGNYYNQGEIRKKELLQSCAVLGIPPSRVMIIDKRDFPDDPEVQWDTELVASTLLQHIHANGTDLVVTFDAEGVSGHSNHIALYKAVRALHSGGKLPKGCSVLTLQSVNALRKYAFLLDLPWTLLSPQDVLFVLTSKEVAQAKKAMSCHRSQLLWFRYLYVLFSRYMRINSLRFL", "length": 252 }, "evidence": [ { "id": "A0A8V1ALZ0", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2B2-1", "protein_name": "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase", "gene_name": "PIGL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAMWLLCVALAVLAWGFLWVWDSSERMKSREQGGRLGAESRTLLVIAHPDDEAMFFAPTVLGLARLRHWVYLLCFSAGNYYNQGETRKKELLQSCDVLGIPLSSVMIIDNRDFPDDPGMQWDTEHVARVLLQHIEVNGINLVVTFDAGGVSGHSNHIALYAAVRALHSEGKLPKGCSVLTLQSVNVLRKYISLLDLPLSLLHTQDVLFVLNSKEVAQAKKAMSCHRSQLLWFRRLYIIFSRYMRINSLSFL", "length": 252 }, "evidence": [ { "id": "A0A8V1ALZ0", "url": "https://omabrowser.org/oma/group/A0A8V1ALZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "N-acetylglucosaminylphosphatidylinositol deacetylase activity", "id": "GO:0000225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ALZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-162857", "name": "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-8855657" ], "output_participant_list": [ "R-ALL-8855661" ], "enzyme_list": [ "A0A8V1ALZ0-1" ], "evidence": [ { "id": "R-GGA-162857", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162857" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8855657", "participant_name": "N-acetylglucosaminyl-PI [cytoplasmic side of endoplasmic reticulum membrane]", "crossref": [ { "id": "57265", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8855661", "participant_name": "glucosaminyl-PI [cytoplasmic side of endoplasmic reticulum membrane]", "crossref": [ { "id": "57997", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1ALZ0", "gene_name": "PIGL", "activity": [ { "ec_number": "3.5.1.89", "activity": "a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + acetate.", "evidence": [ { "id": "A0A8V1ALZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ] }, { "ec_number": "3.5.1.89", "activity": "", "evidence": [ { "id": "A0A8V1ALZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALZ0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.89", "ec_name": "a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + acetate.", "evidence": [ { "id": "3.5.1.89", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.89" }, { "id": "3.5.1.89", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.89" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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231, "header": "tr|A0A8V1AM38-1|A0A8V1AM38_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AM38-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AM38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM38/entry#A0A8V1AM38-1", "sequence": { "sequence": "MEGQETPTAVEPPTAEEETPIAEKTPTAAEETPTAEETRTAAEETPTTVEPPTAAEETPKAAETPTSVETPTAAEETPTAEKTPTAAAVETPTAEEPSIAAEETPTAAEETPTSAEETPTSAEPPTAAETPTAAETPTSVDGAHGRALLLPTGTAQPAASQGKLDVTHQSPALTRQGWPQTHPASRVEKGLLYEVQCEPCLPTKQLCAAGSQQRRSVSCCCCEGWGERGEL", "length": 231, "header": "tr|A0A8V1AM38-1|A0A8V1AM38_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AM38-1" }, "locus": { "chromosome": "17", "start_pos": 35855, "end_pos": 32483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069939.1", "url": "https://www.ensembl.org/id/ENSGALT00010069939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043065.1", "url": "https://www.ensembl.org/id/ENSGALP00010043065.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", 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53, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr53", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 53, 106, 126, 132 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM39-1", "uniprot_ac": "A0A8V1AM39", "uniprot_id": "A0A8V1AM39_CHICK", "mass": { "chemical_mass": 22268.0, "monoisotopic_mass": 22268.0 }, "refseq": { "ac": "XP_004946745", "name": "transmembrane protein 211", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946745" }, "gene_names": [ { "name": "LOC101749175", "type": "recommended", "evidence": [ { "id": "A0A8V1AM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM39" } ] }, { "name": "LOC101749175", "type": "synonym", "evidence": [ { "id": "XP_004946745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946745" } ] } ], "protein_names": [ { "name": "Transmembrane protein 211", "type": "recommended", "evidence": [ { "id": "A0A8V1AM39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM39/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 211", "type": "synonym", "evidence": [ { "id": "XP_004946745", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946745" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004946745.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946745" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM39", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC101749175", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM39", "locus": {} } ], "crossref": [ { "id": "A0A8V1AM39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM39", "database": "AlphaFoldDB", "categories": [] }, { "id": "101749175", "url": "https://www.ncbi.nlm.nih.gov/gene/101749175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101749175", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101749175", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRCAGPP", "url": "https://omabrowser.org/oma/group/WRCAGPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM39", "url": "https://www.orthodb.org/?gene=A0A8V1AM39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] 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[ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM64", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM64", "locus": {} } ], "crossref": [ { "id": "A0A8V1AM64", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM64", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR024829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR16915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16915:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16915:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM64", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQFSQPSELPQQAAKDTMPHTGQSLFCSTALPKNHSDSLPRPPLAIRAVGRPPGLPTKRSRKARRVLYPARVRKYLPRPKKDGAKRWLLVCAGIVLLQVLTEEPEREGLAGGKVPKERLCTLHAQLRAAHLGAAQLRAAENCSREDRAAPEAPVLSFSHQLMGTNFSCKPRMCHDKLGGSCTPSAGSAWLVYPMQSTELR", "length": 200, "header": "tr|A0A8V1AM64-1|A0A8V1AM64_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AM64-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AM64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM64/entry#A0A8V1AM64-1", "sequence": { "sequence": "MQFSQPSELPQQAAKDTMPHTGQSLFCSTALPKNHSDSLPRPPLAIRAVGRPPGLPTKRSRKARRVLYPARVRKYLPRPKKDGAKRWLLVCAGIVLLQVLTEEPEREGLAGGKVPKERLCTLHAQLRAAHLGAAQLRAAENCSREDRAAPEAPVLSFSHQLMGTNFSCKPRMCHDKLGGSCTPSAGSAWLVYPMQSTELR", "length": 200, "header": "tr|A0A8V1AM64-1|A0A8V1AM64_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AM64-1" }, "locus": { "chromosome": "17", "start_pos": 2483269, "end_pos": 2482670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069974.1", "url": "https://www.ensembl.org/id/ENSGALT00010069974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043100.1", "url": "https://www.ensembl.org/id/ENSGALP00010043100.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM64", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM69-1", "uniprot_ac": "A0A8V1AM69", "uniprot_id": "A0A8V1AM69_CHICK", "mass": { "chemical_mass": 79047.0, "monoisotopic_mass": 79047.0 }, "refseq": { "ac": "XP_004946140", "name": "zinc finger protein 750", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946140" }, "gene_names": [ { "name": "ZNF750", "type": "recommended", "evidence": [ { "id": "A0A8V1AM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ] }, { "name": "ZNF750", "type": "synonym", "evidence": [ { "id": "XP_004946140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946140" } ] } ], "protein_names": [ { "name": "Zinc finger protein 750", "type": "recommended", "evidence": [ { "id": "A0A8V1AM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 750", "type": "synonym", "evidence": [ { "id": "XP_004946140", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946140" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004946140.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946140" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF750", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69", "locus": { "chromosome": "18", "start_pos": 3940385, "end_pos": 3932044, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029426", "url": "https://www.ensembl.org/id/ENSGALG00010029426" } ] } } ], "crossref": [ { "id": "A0A8V1AM69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AM69", "database": "AlphaFoldDB", "categories": [] }, { "id": "101750712", "url": "https://www.ncbi.nlm.nih.gov/gene/101750712", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101750712", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PSAYDHY", "url": "https://omabrowser.org/oma/group/PSAYDHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AM69", "url": "https://www.orthodb.org/?gene=A0A8V1AM69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14678:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14678:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15269", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15269", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004946140", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946140", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVIKCPKTSSLEPKQINHLEPTVKPTSSKSATNGLSNLDSKPQYAFPKEDAKENVELQNQATNTAIQGQKPAIQKELTPASTSAESTLGMQPLLDSIVRPSAFVPVGEHRDSKGPETSEVPEILSLSNKSSPFHTKSAFHAPSHPWKAGSPFLPEFPHKVPPTKGFGSIPPYMQPMIPEYSPHFYEHRLAIYTPYLLPGNSDCESSALSVYGTQDQRHFLPHPGPLPKHINPSAYEHYRLFQQYHSTPPIPYGFCRPTDPPFYRFSHVAGINRDQSSHLMEETTLLYPASLSPSQQYPLGSHKKQADYEKEITLLHAKSHSKDDQNERENAKMSPLAGSAATGSPGRPSPTNFTQTSHACEGLFDLSNKSSSTSLGKYDQAEENLTAFRPVRKSTDQPALPPSVPTQQDREDSPSSINVTDEDSYTPNESHNNEGSLSNTEDSTGIAPLNLSKKADTNAGPPHEHAYKAMSKTESQSFLELQDMPLNLSVKDSCNTVSLKTSSRSPAHDNGAATSPKTENENSGAESSGACNPKNPINSACDKPFLSHHNEAQDLRIIDSCDEQKQTAAVALCQLAAYSPSTVRMDNEGQSPQDCNALSTESTSNSSDTQDTQCSQKVKGQKRTSQKESAKSQQSTKRVRPNDCSRVFTLRKRTRVS", "length": 717, "header": "tr|A0A8V1AM69-1|A0A8V1AM69_CHICK Isoform 1 of Zinc finger protein 750 OS=Gallus gallus OX=9031 GN=ZNF750 PE=4 SV=1 CANONICAL=A0A8V1AM69-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69/entry#A0A8V1AM69-1", "sequence": { "sequence": "MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVIKCPKTSSLEPKQINHLEPTVKPTSSKSATNGLSNLDSKPQYAFPKEDAKENVELQNQATNTAIQGQKPAIQKELTPASTSAESTLGMQPLLDSIVRPSAFVPVGEHRDSKGPETSEVPEILSLSNKSSPFHTKSAFHAPSHPWKAGSPFLPEFPHKVPPTKGFGSIPPYMQPMIPEYSPHFYEHRLAIYTPYLLPGNSDCESSALSVYGTQDQRHFLPHPGPLPKHINPSAYEHYRLFQQYHSTPPIPYGFCRPTDPPFYRFSHVAGINRDQSSHLMEETTLLYPASLSPSQQYPLGSHKKQADYEKEITLLHAKSHSKDDQNERENAKMSPLAGSAATGSPGRPSPTNFTQTSHACEGLFDLSNKSSSTSLGKYDQAEENLTAFRPVRKSTDQPALPPSVPTQQDREDSPSSINVTDEDSYTPNESHNNEGSLSNTEDSTGIAPLNLSKKADTNAGPPHEHAYKAMSKTESQSFLELQDMPLNLSVKDSCNTVSLKTSSRSPAHDNGAATSPKTENENSGAESSGACNPKNPINSACDKPFLSHHNEAQDLRIIDSCDEQKQTAAVALCQLAAYSPSTVRMDNEGQSPQDCNALSTESTSNSSDTQDTQCSQKVKGQKRTSQKESAKSQQSTKRVRPNDCSRVFTLRKRTRVS", "length": 717, "header": "tr|A0A8V1AM69-1|A0A8V1AM69_CHICK Isoform 1 of Zinc finger protein 750 OS=Gallus gallus OX=9031 GN=ZNF750 PE=4 SV=1 CANONICAL=A0A8V1AM69-1" }, "locus": { "chromosome": "18", "start_pos": 3939403, "end_pos": 3936805, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071191.1", "url": "https://www.ensembl.org/id/ENSGALT00010071191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043882.1", "url": "https://www.ensembl.org/id/ENSGALP00010043882.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 86, "start_aa": "Thr", "end_pos": 86, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr86", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101750712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101750712", "resource": "KEGG Pathway" }, { "id": "R-GGA-212436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212436", "resource": "Reactome", "description": "Generic Transcription Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I2Q4-1", "protein_name": "Zinc finger protein 750", "gene_name": "Znf750", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVPKCPKSTLLDPKQTHQSEPTSKQVTSKSLPNGLSSFDPKSQQGSAKEETKENLEMQARGTHKGPQKTALQKEVTSEAILSTQPGLDSGVRPSAFVPVGEHRLRGPEDTEASEMLALTSSTTKATSFHAKSAFHTPGYPWKAGSPFLPPEFPHKIPSSKGFGAISPYMHPAIPEYTHPFYTEHGLTAIYSPYLLPGNTPECDTTLLSVYGSQDQRHFLSHPGPIPKHLNTTPSTYDHYRFFQQYHSNLPIPYGFYRPESAFPSYSLRLPPVPGITRDQSSRLLEEAALAYPASSPSELNLSNSHRKHTEFEKESPVSEAKDPSKDGQRDAEEAKMSPRAGSAATGSPGRPSPTNFTQTSQTLEGLCDLSNKAASSGTLERLQQPEQSPTAFKPVQRGSESPHSQPPANRTESPKSLQAMNSDSPTQIGTSSSLITEEPPSSPEDHSRIAPLNLSKKLETNPAATYGSMYVDNAQADTLGFSGLQDLPLNLSVKDSCNAWAPRPVFPSPPQGAEPAAAPKTETKGSEGRTSHVETQQDKAHSRTTPDVHTVDSSEEQKQTAAVALCQLAAYSPGNVRVGDDESTAQESTCQEVPTHSSTENQGAQCDLRPKGQKRTSQRDAGKSQQGTKKPKLNDTVPRVLTLRKRTRVS", "length": 710 }, "evidence": [ { "id": "A0A8V1AM69", "url": "https://omabrowser.org/oma/group/A0A8V1AM69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2VDR9-1", "protein_name": "Zinc finger protein 750", "gene_name": "ZNF750", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVPKCSKPNSSDPKQTNQPDPVVKPTSSKPVPSGLSHLDAKLQHSLAKDDIKENLDLHARGPHRCLGQKPTPHKEAAPPSPAPEAAVGTQPVLEGAVRPSAFVPVGEHRLKGQELTETPEALALTHAPAKASSFHTKSAFHAPGYPWRAGSPFLTPEFPHKIPSTKGFGATSPYVHPSITEYPPHFYTEHGLATIYSPYLLAGNSPECDSPLLSVYGAQDQRHFLPHPGPIPKHLNPAPSTYDHYRFFQQYHSSLPIPYGFYRPESAFSSYGLRLPPVAGISRDQSSHLLEEAALGYQALSPSKLNSSNSHKKHTELEKQSPTPEAKEPSKDGQRDTEGTKMSPRAGSAATGSPGRPSPTNFTQTSQPCAGLCGLSDAPASSAPGRIPPPEQGLAAFKPIKKNTEHPHSQAPENRAVSPKSLEALSTDAPTQLGSLEAAPSSPEDGSRAAPLNLSTKPEAEPAATCSPAHGGFVEPQDAPLNLSVKDPCNALTSRPSVCSPPRGAEPAAAPTPSPTQQREPASSGDGPDPSSVEAPVPSPTGKAQDIRAADSDEQKQTAAVALCQLAAYSPGNVEPAAQEPTCRPDAPTPRAPESQEAQCDLRPKGQKRTSPREVGKGQQGSKKAKPSDTARVFTLRKRTRVS", "length": 703 }, "evidence": [ { "id": "A0A8V1AM69", "url": "https://omabrowser.org/oma/group/A0A8V1AM69/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R3N9-1", "protein_name": "Zinc finger protein 750", "gene_name": "Znf750", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRIPKCPKSSSLDPKQTHQPEPTSKPAISKSLLNGLSSFDPKSQQGSAKEDAKENLEMQARGAHKGPQKPALQKEMTPEAILSTQPSLDNGVRPSAFVPVGEHRLRGPEDTEAPEMLALTNSTTKATSFHAKSAFHTPGYPWKAGSPFLPPEFPHKIPPTKGFGAISPYMHPAIPEYPPPFYTEHGLAALYSPYLLTGNTPECETTLLSVYGAQDQRHFLSHPGPIPKHLSTSPSAYDHYRFFQQYHSNLQIPYGFYRPESAFPSYSLRLPSVTGITRDQNPRLLEDAALAYPASSPTELNLSNSHRKHTEFEKESPVPEAKDPSTDGQRDAEEAKMSPRAGSAATGSPGRPSPTNFTQTSQTFEGLCDLSNKAASSGALERLQQPEQSPTAFKPVQRGSESPHSQPPASRTESPKSLQAVNSDPPAQTGSSTSFITEAPPSSPEDHSRIGPLNLSKKPETNPAATYGPMYASNAQADPLGFSGLQDLPLNLSVKDPCNAWAPRPALPGPPQGAEPPVPPKTETKGSEDRTSHVETEQDEAHSRTTPDVHTVDSSDEQKQTAAVALCQLAAYSPGNVRVGDEESPAQESTHREVPTLSSTENQEAQCDLRPKGQKRTSQRDAGKSQQGTKKPKLNDTVPRVLTLRKRTRVS", "length": 710 }, "evidence": [ { "id": "A0A8V1AM69", "url": "https://omabrowser.org/oma/group/A0A8V1AM69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32MQ0-1", "protein_name": "Zinc finger protein 750", "gene_name": "ZNF750", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRVPKCPKSNSLDPKQTNQPDATAKPASSKSVANGLSAFDSKLQHSSAREDIKENLELQARGTHRCLGQKPALHRASPCKSPAPEAALGAQPALEGAARPSAFVPVGEHRLKGPDNAEAPETLALHNPTAKAVSFHTKSAFHTPGYPWKAGSPFLPPEFPHKISSTKGLGAISPYMHPTIPEYPPHFYTEHGLATIYSPYLLAGSSPECDAPLLSVYGTQDPRHFLPHPGPIPKHLAPSPATYDHYRFFQQYPSNLPIPYGFYRPESAFSSYGLRLPPVTGLTRDQSSHLLEEATLVYPASSPSRLNPSDPNRKHVEFESPIPEAKDSSKAGQRDTEGSKMSPRAGSAATGSPGRPSPTDFMQTSQTCEGLYDLSNKAASSALGRLYPPEQSLTAFRPVKKSTECLPAQAAETTAESPVSLNVVNGDPPAPTGSASLVSEAAPSSPDDSSGMGPLNLSKKSEINLAATHEPTYQGSPQAETASFSELQDLPLNLSVKDPCNTQAPRPAFPGRPRAAEPAAAVPQKTGTEGSEDGPSHPETKPGSLDGDGAPPTGPGEEAPDACAVDSSEEQKQTAAVALCQLAAYSPRNIRVGDGDAAAPEPACRQDTPTLSSMESQEAQCDLRPKGQKRTSLRDAGKSQQGAKKAKLQDTARVFTLRRRARVS", "length": 723 }, "evidence": [ { "id": "A0A8V1AM69", "url": "https://omabrowser.org/oma/group/A0A8V1AM69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q568E2-1", "protein_name": "Zinc finger protein 750", "gene_name": "znf750", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METLQGRKPKKPHYIPRPPGKPFKYQCFQCPFTCNIKSHLFNHMKYNLCKNSISLVSQRMEQTGKASRASQHSPAFSHNSKELPLDAESTKPIENVKIEKAVTKEAREKPQSPIKEVSKDDTEPALEAKDKSEDMDIAQNKISSAFSPVARTCESEALSLSPHKDDQSTIPHFYQQIAPWVTSASSAHLLPPIPEYPPYMVPERSLPPLYAPYPHNQASTPAYQVTPRETQRPLVPSPLIPPNSSLLHPYHYRYGHSIFPSPPLPYSFYQHPELSIPLQRSRYLPLDVYSSRFYPREYGGHLVPLTHPESYSRLAEDRAVQEHNTGDKGIRESPLEGCDASGSPDRPSTADVTQRIPVGLRLASHGESHSGSQSHIISGSTKANDNLPKMPCGQNQEKMLQKTERYDSQTTISSRSSDISDKEEDEETEEEIGPLNLSKRDQATSNNMTHHHYPDRELHYDSESSQEEAPLNLCLRVQSSNQALPNTSETPEKETISNAEVSTTESPQDLEPCDQRQTAAFALCQLASSRDIINDTSVKQQDVTESQNTKCLPSPDNCSVKDSPNILNASMVALGQKRANNRPLRHTNKRAKVKEPSRPRRKRSQNC", "length": 607 }, "evidence": [ { "id": "A0A8V1AM69", "url": "https://omabrowser.org/oma/group/A0A8V1AM69/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BH05-1", "protein_name": "Zinc finger protein 750", "gene_name": "Znf750", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQDRIPKCPKSSSLDPKQTHQPEPTSKPATSKSLLNGLSSFDPKSQQGSAKEDAKENLEMQARGAHKGPQKPALQKEMAPEAILSTQPCLDSGVRHSAFVPVGEHRLRGPEDTEATEVLANSTTKASSFHAKSAFHTPGYPWKAGSPFLPPDFPHKISSTKGFGAISPYMHPAIPEYPHPFYAEHGLAAIYSPYLLTGNTPECETTLLSVYGTQDQRHFLSPAGPIPKHLNTSPSTYDHYRFFQQYHSNLPIPYGFYRPESAFPSYSLRLPSVTGITRDQSSRLLEDATLAYPASSPSELNLSSSHRKHTECEKGSPVPEAKDPSKDGQRDAEEAKMSPRAGSAATGSPGRPSPTNFTQTSQTFEGLCDLSNKAASSGTLERLQQAEQSPTAFKPVQRGSESPHSQPPANRTESPKSLQAMNGDPPAQTGSSNSFITEAPPSSPEDHSRIGPLNLSKKLETNPAATYGPMYASNAQADTLQDLPLNLSVKDLCNAWAPRPALPGPPQGAEPAATPKTETKGSEDRTSRVETPQDKAHSRTTPDVHTEDSSDEQKQTAAVALCQLAAYSPGNVRVADEEGTVQEPTRQDVPTLSATENLEAQCDLRPKGQKRTSQRDTGKSQQGTKKPKLNDPVPRVLTLRRRTRVS", "length": 703 }, "evidence": [ { "id": "A0A8V1AM69", "url": "https://omabrowser.org/oma/group/A0A8V1AM69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "epidermis development", "id": "GO:0008544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM69" }, { "id": "PF15269", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15269" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Zinc finger protein 750-like zinc finger", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 57, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 86 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 665, "end_pos": 667 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AM71-1", "uniprot_ac": "A0A8V1AM71", "uniprot_id": "A0A8V1AM71_CHICK", "mass": { "chemical_mass": 187730.0, "monoisotopic_mass": 187730.0 }, "refseq": { "ac": "XP_415405", "name": "complement C5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415405" }, "gene_names": [ { "name": "C5", "type": "recommended", "evidence": [ { "id": "A0A8V1AM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM71" } ] }, { "name": "C5", "type": "synonym", "evidence": [ { "id": "XP_415405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415405" } ] } ], "protein_names": [ { "name": "Complement C5", "type": "synonym", "evidence": [ { "id": "A0A8V1AM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM71/entry#names_and_taxonomy" } ] }, { "name": "complement C5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415405" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415405.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415405" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM71", "locus": { "chromosome": "17", "start_pos": 8927565, "end_pos": 8951200, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029141", "url": "https://www.ensembl.org/id/ENSGALG00010029141" } ] } } ], "crossref": [ { "id": "cd00017", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00017", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03582", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03582", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417122", "url": "https://www.ncbi.nlm.nih.gov/gene/417122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002890", "database": "InterPro", 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"MAILMYFFVLVFSGTAFSQDKTYVLTAPKVFRVGTSEKVVVQAFGYEKEFAVNLALRSFPDKLVAYSSGHISLNPDNNFQSSVTVTLQPTDLAGPEDSVKYVYLEAVSPHFTGLKKVPVSYENGFLFVHTDKPIYTPDQSVKVRVYSLNEELQPARRETVLTVVDPDGVKVDIIEENDFTGIVSFPDFKIPPNPKYGIWKIEAKYKKNFITSAVAKFEVKEYAMPSFSIVIEPENNFISSDKFENFRIAVKASYFYNKRLAKADVFLRFGIIEGTEKRMMPRAMLVAKLTNGVAEINFNSKKAVSSLGFQSLEELDGSYLYIAASVVESMGGLSGEVEFSEVKYAVSPYTLSLIATPLFIKPGLPFFIKVQVKDTVDRFVGNIPLVITAKSFSQQMDETELISEGSESGRRETSINDGTALFVVNVPTDSNLLEFQVKTADPHLSDENQATKTYEARVYSSLSQSYLYIDWASNHKILSVGDFISINIYPRSRYIHNIHHYSYLITSKGKIVSFGTQKRIKDLEYEHLSFQITQEMVPSARLIVYYIVGEEPAELVADSVWLNVEQKCGSSLDIKLLSSKETHKPAEIVSLNMKTQFDSFVALSSIDKAIYGVTGRGKRAMEKIMLKLEKSDLGCGAGGGQNNVDVFRMAGLTFLTNANADDSNEAGGKCSEVIRTKRSDFEEQVLKEASKYKHLEIRKCCMHGVKAYPVSETCSDRARRIQSHAKCVSAFRHCCEFANRLREEEPSKLLILARKQFEAFLELDEAEVRSYFPESWLWEVHQVSPRSKTLSITLPDSLTTWEVQGVGISDKGICVAAPLEVQVVKDIFLSIYVPYSVVRGEQIELKGSVYNHRASAIKFCVKIAAGDGICSSGDSATTRQRMHNCNLKNLGAGSSSPIVFRILPLELGLHTINFTLLTTGSSETVVKTLRVMPEGIKKELHAGFTLDPQGVYGSIKRRQEFRYKIPLNLVPKTKIDRSVSVKGHLMGEVIATILSPEGLSILTNLPKGSAEAELMTIAPVFYVFHYLEASNNWHILGPETLTSRTAMRRKMKEGIVSVLSFRNSDFSYSMWKNGKASTWLTAFALRILGQVNQYINLDQISVCNSLLWLIDNCQMPDGSFSEFSDYQPVKLQGTLPREAKEKSLYLTAFSIIGIEKSIKICPTQKIHDAKNKAGDYLLTNVQSAQSPFTMAIISYALALVDLNHQAARSLFSALKREASVIGDPPIYRFWKDDFKTSDLLAPSPVTAQMVETTAYALLTALLRGDKNYANPIIKWLSEEQRYGGGFYSTQDTVNALEALTEYSLLVKRLHLDMGIKVAYRNHGDLHLFKLTEDNFVGRSVTVPLDDDIYVSTGSSTGIATVNVRTVYNVMGTSEESCNFELKIVPKRDDGYRGEDGGPLGRLEACAKYRPSRREPQSGSAHVVMDISLVSGLEANSEDLSTLASGVDQLIADYEIKDGHVILQIDSVPADRFLCVGFRISQLFHVGMLNPGTFSVYEYHAPDKRCTVFYNPYGNEKLVRLCEGDECKCMEAECSKVQERLDQSITADTRREVACQNDIAYVYKVNILSRSEEGYFVKYSATILDLYKRGQAFAQKNNEVTFVKKKTCANVELSPGMQYLIMGKEALKINIGYSFRFQYPLDSSTWIEWWPPNTACTFCQEFLNRMEDFVEDLIISGC", "length": 1677, "header": "tr|A0A8V1AM71-1|A0A8V1AM71_CHICK Isoform 1 of Complement C5 OS=Gallus gallus OX=9031 GN=C5 PE=1 SV=1 CANONICAL=A0A8V1AM71-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AM71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM71/entry#A0A8V1AM71-1", "sequence": { "sequence": "MAILMYFFVLVFSGTAFSQDKTYVLTAPKVFRVGTSEKVVVQAFGYEKEFAVNLALRSFPDKLVAYSSGHISLNPDNNFQSSVTVTLQPTDLAGPEDSVKYVYLEAVSPHFTGLKKVPVSYENGFLFVHTDKPIYTPDQSVKVRVYSLNEELQPARRETVLTVVDPDGVKVDIIEENDFTGIVSFPDFKIPPNPKYGIWKIEAKYKKNFITSAVAKFEVKEYAMPSFSIVIEPENNFISSDKFENFRIAVKASYFYNKRLAKADVFLRFGIIEGTEKRMMPRAMLVAKLTNGVAEINFNSKKAVSSLGFQSLEELDGSYLYIAASVVESMGGLSGEVEFSEVKYAVSPYTLSLIATPLFIKPGLPFFIKVQVKDTVDRFVGNIPLVITAKSFSQQMDETELISEGSESGRRETSINDGTALFVVNVPTDSNLLEFQVKTADPHLSDENQATKTYEARVYSSLSQSYLYIDWASNHKILSVGDFISINIYPRSRYIHNIHHYSYLITSKGKIVSFGTQKRIKDLEYEHLSFQITQEMVPSARLIVYYIVGEEPAELVADSVWLNVEQKCGSSLDIKLLSSKETHKPAEIVSLNMKTQFDSFVALSSIDKAIYGVTGRGKRAMEKIMLKLEKSDLGCGAGGGQNNVDVFRMAGLTFLTNANADDSNEAGGKCSEVIRTKRSDFEEQVLKEASKYKHLEIRKCCMHGVKAYPVSETCSDRARRIQSHAKCVSAFRHCCEFANRLREEEPSKLLILARKQFEAFLELDEAEVRSYFPESWLWEVHQVSPRSKTLSITLPDSLTTWEVQGVGISDKGICVAAPLEVQVVKDIFLSIYVPYSVVRGEQIELKGSVYNHRASAIKFCVKIAAGDGICSSGDSATTRQRMHNCNLKNLGAGSSSPIVFRILPLELGLHTINFTLLTTGSSETVVKTLRVMPEGIKKELHAGFTLDPQGVYGSIKRRQEFRYKIPLNLVPKTKIDRSVSVKGHLMGEVIATILSPEGLSILTNLPKGSAEAELMTIAPVFYVFHYLEASNNWHILGPETLTSRTAMRRKMKEGIVSVLSFRNSDFSYSMWKNGKASTWLTAFALRILGQVNQYINLDQISVCNSLLWLIDNCQMPDGSFSEFSDYQPVKLQGTLPREAKEKSLYLTAFSIIGIEKSIKICPTQKIHDAKNKAGDYLLTNVQSAQSPFTMAIISYALALVDLNHQAARSLFSALKREASVIGDPPIYRFWKDDFKTSDLLAPSPVTAQMVETTAYALLTALLRGDKNYANPIIKWLSEEQRYGGGFYSTQDTVNALEALTEYSLLVKRLHLDMGIKVAYRNHGDLHLFKLTEDNFVGRSVTVPLDDDIYVSTGSSTGIATVNVRTVYNVMGTSEESCNFELKIVPKRDDGYRGEDGGPLGRLEACAKYRPSRREPQSGSAHVVMDISLVSGLEANSEDLSTLASGVDQLIADYEIKDGHVILQIDSVPADRFLCVGFRISQLFHVGMLNPGTFSVYEYHAPDKRCTVFYNPYGNEKLVRLCEGDECKCMEAECSKVQERLDQSITADTRREVACQNDIAYVYKVNILSRSEEGYFVKYSATILDLYKRGQAFAQKNNEVTFVKKKTCANVELSPGMQYLIMGKEALKINIGYSFRFQYPLDSSTWIEWWPPNTACTFCQEFLNRMEDFVEDLIISGC", "length": 1677, "header": "tr|A0A8V1AM71-1|A0A8V1AM71_CHICK Isoform 1 of Complement C5 OS=Gallus gallus OX=9031 GN=C5 PE=1 SV=1 CANONICAL=A0A8V1AM71-1" }, "locus": { "chromosome": "17", "start_pos": 8951150, "end_pos": 8927645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070419.1", "url": "https://www.ensembl.org/id/ENSGALT00010070419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043110.1", "url": "https://www.ensembl.org/id/ENSGALP00010043110.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Formation of high affinity C5 convertase of the classical pathway of complement.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Rawal N, Pangburn MK", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132285", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132285" } ], "reference": [ { "type": "PubMed", "id": "12878586", "url": "https://glygen.org/publication/PubMed/12878586" } ] }, { "title": "Factor I-dependent inactivation of human complement C4b of the classical pathway by C3b/C4b receptor (CR1, CD35) and membrane cofactor protein (MCP, CD46).", "journal": "Journal of biochemistry", "date": "1992", "authors": "Masaki T, Matsumoto M, Nakanishi I, Yasuda R, Seya T", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "1386357", "url": "https://glygen.org/publication/PubMed/1386357" } ] }, { "title": "Regulator of complement activation (RCA) locus in chicken: identification of chicken RCA gene cluster and functional RCA proteins.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2005-08-01", "authors": "Oshiumi Hiroyuki, Shida Kyoko, Goitsuka Ryo, Kimura Yuko, Katoh Jun, Ohba Shinya, Tamaki Yuichiroh, Hattori Takashi, Yamada Nozomi, Inoue Norimitsu, Matsumoto Misako, Mizuno Shigeki, Seya Tsukasa", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "16034113", "url": "https://glygen.org/publication/PubMed/16034113" } ] }, { "title": "Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex.", "journal": "Acta crystallographica. Section D, Biological crystallography", "date": "2007", "authors": "Huang Y, Fedarovich A, Tomlinson S, Davies C", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "17505110", "url": "https://glygen.org/publication/PubMed/17505110" } ] }, { "title": "The chemotactic receptor for human C5a anaphylatoxin.", "journal": "Nature", "date": "1991", "authors": "Gerard NP, Gerard C", "evidence": [ { "database": "Reactome", "id": "R-GGA-2173345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173345" } ], "reference": [ { "type": "PubMed", "id": "1847994", "url": "https://glygen.org/publication/PubMed/1847994" } ] }, { "title": "Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells.", "journal": "Biochemistry", "date": "1991-03-26", "authors": "Boulay F, Mery L, Tardif M, Brouchon L, Vignais P", "evidence": [ { "database": "Reactome", "id": "R-GGA-2173345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173345" } ], "reference": [ { "type": "PubMed", "id": "2007135", "url": "https://glygen.org/publication/PubMed/2007135" } ] }, { "title": "Complement: a key system for immune surveillance and homeostasis.", "journal": "Nature immunology", "date": "2010", "authors": "Ricklin D, Hajishengallis G, Yang K, Lambris JD", "evidence": [ { "database": "Reactome", "id": "R-GGA-2173345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173345" } ], "reference": [ { "type": "PubMed", "id": "20720586", "url": "https://glygen.org/publication/PubMed/20720586" } ] }, { "title": "Unique structure of iC3b resolved at a resolution of 24 A by 3D-electron microscopy.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2011", "authors": "Alcorlo M, Martinez-Barricarte R, Fernandez FJ, Rodriguez-Gallego C, Round A, Vega MC, Harris CL, de Cordoba SR, Llorca O", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "21788512", "url": "https://glygen.org/publication/PubMed/21788512" } ] }, { "title": "Complement anaphylatoxin C3a is a potent inducer of embryonic chick retina regeneration.", "journal": "Nature communications", "date": "2013", "authors": "Haynes Tracy, Luz-Madrigal Agustin, Reis Edimara S, Echeverri Ruiz Nancy P, Grajales-Esquivel Erika, Tzekou Apostolia, Tsonis Panagiotis A, Lambris John D, Del Rio-Tsonis Katia", "evidence": [ { "database": "Reactome", "id": "R-GGA-2173345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173345" } ], "reference": [ { "type": "PubMed", "id": "23942241", "url": "https://glygen.org/publication/PubMed/23942241" } ] }, { "title": "Complement S-protein (vitronectin) is associated with cytolytic membrane-bound C5b-9 complexes.", "journal": "Clinical and experimental immunology", "date": "1988", "authors": "Bhakdi S, Kaflein R, Halstensen TS, Hugo F, Preissner KT, Mollnes TE", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "2466593", "url": "https://glygen.org/publication/PubMed/2466593" } ] }, { "title": "Molecular organization of C9 within the membrane attack complex of complement. Induction of circular C9 polymerization by the C5b-8 assembly.", "journal": "The Journal of experimental medicine", "date": "1982", "authors": "Podack ER, Tschoop J, Muller-Eberhard HJ", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132267", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132267" } ], "reference": [ { "type": "PubMed", "id": "6177822", "url": "https://glygen.org/publication/PubMed/6177822" } ] }, { "title": "Generation of three different fragments of bound C3 with purified factor I or serum. I. Requirements for factor H vs CR1 cofactor activity.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1982", "authors": "Ross GD, Lambris JD, Cain JA, Newman SL", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "6214588", "url": "https://glygen.org/publication/PubMed/6214588" } ] }, { "title": "Interactions of soluble CD59 with the terminal complement complexes. CD59 and C9 compete for a nascent epitope on C8.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1993", "authors": "Lehto T, Meri S", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "7691959", "url": "https://glygen.org/publication/PubMed/7691959" } ] }, { "title": "Covalent binding properties of the human complement protein C4 and hydrolysis rate of the internal thioester upon activation.", "journal": "Protein science : a publication of the Protein Society", "date": "1993", "authors": "Sepp A, Dodds AW, Anderson MJ, Campbell RD, Willis AC, Law SK", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132281", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281" } ], "reference": [ { "type": "PubMed", "id": "8495193", "url": "https://glygen.org/publication/PubMed/8495193" } ] } ], "pathway": [ { "id": "R-GGA-166665", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166665", "resource": "Reactome", "description": "Terminal pathway of complement" }, { "id": "R-GGA-174577", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174577", "resource": "Reactome", "description": "Activation of C3 and C5" }, { "id": "R-GGA-2132267", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132267", "resource": "Reactome", "description": "Formation of membrane attack complex (MAC)" }, { "id": "R-GGA-2132281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132281", "resource": "Reactome", "description": "Regulation of complement cascades" }, { "id": "R-GGA-2132285", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132285", "resource": "Reactome", "description": "Complement Cascade" }, { "id": "R-GGA-2173345", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173345", "resource": "Reactome", "description": "Anaphylatoxins initiate inflammatory responses" }, { "id": "R-GGA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AIM8-1", "protein_name": "Complement C5", "gene_name": "C5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLWGILCFLIFLGKTWGQEQTYVISAPKILHVGAAENIVVQVYGYTEAFAVTVSVKSYPDKKITYSSMYVILSTENKFQNSAFLTIQPKQLLGKPNSVSHVYLDIVSKHFSRSKKIPVTYDNGFLFIHTDKPVYTPHQSVKVRVYSLNDELKPAKRETVLTFIDPQGSEVEVLEENDYTGIISFPDFKIPSNPKYGVWTIQAKYREDFSTTGTAYFEIKEYVLPHFSVSIEPENNFIGYKDFNDFEITVKARYFYNKVVSEADVYMFFGIREDLKDEQKVMMQKAMRNTMLINGIAKVTFNSETAIKELSYDSLEDLNNKYLYIGVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFVKPGIPYSIKVQVKDSLDLLVGGVPVILSAQTLDANQETSDLESKKSVTRSRDGVASFVVNLPAGVTVLEFNIRTEDPDLPDENQARANYRAIAYSSLSQSYLYIEWTQNYKPVLVGEHLNVVVTPKSPYIDKITHYNYLILSRGKIVHFGTREKLSNSAYQSINIPVTQNMVPSARLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPNTDTYSPGQHVSLNLVTELDSWVALSAVDKAIYGVQMTAKKPLERVFQTFEKNDLGCGAGGGRNNADVFHLAGLTFLTNANTDDIRENDEPCKDILRPKRMLQKKIEEEAAKYKYAMLKKCCYDGAYRNDDETCEERAARIKIGPKCVKAFKDCCYIANQVRAEESHKNIQLGRLHIKTLLAVTNPEIRSYFPESWLWEVHHVPRRNQLQFVLPDSLTTWEIQGIGISNSGICVTDTLNAKVLKDVFLEMSIPYSVVRGEQIQLKGTVYNYGTSGVLFCVKMPPVEGICSSGSPGIDPQGKKSSRCQPQKIEGSSSHLVTFDVLPLEIGLHNINFSLETSLGREILVKTLRVVPEGVKRESYAGITLDPRGIYGAMTRRKEFPYRVPLDLVPKTKVKRIVSVKGLLIGEVMSAVLSQEGIDILTHLPKGNAEAELMSIVPVFYVFHYLEAGNNWNIFSSNSLAQRQNLQKKLREGVVSVMSFRNADHSYSMWKSGSASTWLTAFALRVLGQASKYIDQDLNSICNSILWLVEKCQLGNGSFKENSEYQPIKLQGTLPIEAQENTLYLTAFAVIGIRKAFDLCPLMKISMALTKADTFLLENTRSTRSTFALAIAAYALSLGDKSHPQFRSIVSALKKEALVKGNPPIYRFWKDDLQKKDRSVPNTGTARMVETTAYALLTSLNLKDMNYVNPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLIKNFLLNMDVKVSYKHRGDFYHYKITEKNFIGRPVEVPLNDDLVVFSTGQNSGLATVHVKTVVHKTSTSEEVCSFDLKIEIQDIEASSYSSSEYKRIVACASYKPSREESSSGSSHAVMDISLPTGVNANAEDLRALVEGVDQLLTDYEIKDGHVICQLNSIPSNNFLCVRFRIVELFQVGFLSPATFTVYEYHRPDKQCTMFYSMSQTKLQKVCEGVTCKCVEADCGQMQTEVDLTISVNTRKETACKPEIAYVYKVKIIAMTEESAFVKYTASLLDVYKAGEAVAEKGSEITFIKKTTCTNANLEKGKQYLIMGKEALQIKHNFNFKYIYPLDSSTWIEYWPTDTACPSCQTFLANLDEFTEDIFLNNCENA", "length": 1677 }, "evidence": [ { "id": "A0A8V1AM71", "url": "https://omabrowser.org/oma/group/A0A8V1AM71/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7FCV2-1", "protein_name": "Complement C5", "gene_name": "c5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARLLLFCIFNLFVCFTVQENVYLITAPKVLRLDASETVVVQLFGFDQETTVHLHLKNTLAVGNKEYDYQSLKLNAANNYQASATLRILAKDFPKEDTSVYLQTISSAFTDNVKIPVTTVNGFLFIQTDKPLYTPEQEVQVRVYSLNEELRKSARTVTLTFQDPRGVKVEIIDMTDINGAKPLLPPFKIPLKPIYGIWKIVATYADNFETTATAEFEVKEYVLPSISVQIEPETNYISEENFDTFKLKISAKYVQGMPVKSANILLKFGYSTPEETVIIPSTYRSYMLYNGKMEVDLDIRSALSSKPDAPQFLNAMKENTFLYVEVLLQESTGGLSQEAVLSHVKFVETPFTLSIIATPPFIKPGLPYAMRVLVKDPLGEPVKDVSVTMRATATTVDNLSDNLKFLGHQDSVTVPSSKDGVAYFTCNIPANVKNAEFTFETEDASWSQGPLTLKAESYVSVNHRYLYIDLPPESSVFEVGQYVDISVVFSYRDYLSLDTFSYQIISKGKVVKYDTVKRVSEKSQSLNIKITPDMVPSARLLVYYVLYGEEKAELVADSTWIDVKAKCVKNLNLELSTLKLQDDYKPKDKLEIKVSSRSKGESLVAFSAVDTALFNLRTNKKDPLKKILQHVEKSDLGCGKGGGKNNADVFDRAGLMFITNANAKASSAGGTCSDTLRPKRSVDLKKKFEDKAQKYGAFREYCLSGTRSSPTLETCKDRANRVTLPNKKTRRDYEKEKYCRLAFEQCCVFAKDLRKENAENIILSRAAIDFLMDAPLSQVRSYFPESWLWEEHLSKSGSVSISKTLPDSITTWELKAVGVFNEGICVSDKRIPVSQDIWVDVPLPYSMVRGEQILLKGSVYNQRSSGIKFTVTLTASSAVCVFHGAQQGKPDKTNENSGQVAGGSVAMVSFYIMALEAGTHTLTFTLTTDWITESVVKKLRVVPEGIRMEEYIGKRIDPNGVFGTPMRKLEFKNVIPPKIVPKSSVDRIITVNGEVLGDILSILNNPEGIKMLTNLPRGSAELELMSLLPVYYVYHYLDKTEKWNILGKEAAASEKELKRKMQAGITSIMSFQLKNGEAFSMWAQKDKTPSTWVTALIIKTLSDIHEYVYVDTDVLANAIHWLIKNCQNEDGSFSELAKTNPHKLMGAGVGVTEKSVYLTSYVMIGIKNALKIPNLKLQVFKDALDRGMQYLISRFRKSSHKIESLYVRAIASYAMTVADIDDGTAVNVYENIKKKAKIDGNPPRVCFWQESDTNIDPLKPSSVTAKSVETTVYVLLNTLTRGETEYAKPILNWLTQDQRYGGGVYSTQDTILTLEALTMYSIKAREANLNMVVDIEYKTRGERISRIQLTQQKPVAKPIEVTQNDDVIVKTAMSTGVSFVKLKTVYYVMTESNKSCLFDTTIDIHDSDQNSDDPMLLSQRIVACAKFKPPENSLETESALTVMEINLPTGVTPVLEDLDEYQNGLESRISNYEVIGDKVVLQIDSIPSDNFYCVGFRILEEFETGMTKASEFTVYEYQAPAFKCTKLYQKQTRKLLRLCEEDHCQCMAAECCNFKSTIDPAITADQRTADICKESVKYALKVVIDSSEAGGDFVTYKATVQSVLKKGETDDLKTDSEVEFIKKASCNSTQFEIGKQYLTMTAESMKIQVNRAYKYKFPLDSEAWVDWWPLESDCSDANCKQYVKVLEGFEFEYLLNGCDLMSSR", "length": 1704 }, "evidence": [ { "id": "A0A8V1AM71", "url": "https://omabrowser.org/oma/group/A0A8V1AM71/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MY85-1", "protein_name": "Complement C5", "gene_name": "C5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLWGILCFLIFLGKSWGQEQTYVISAPKVFHVGAYENVVIQAYGYTEEFDATVSIKSFPDKKVTYSSGHVTLSAENKFQNSATLTIQPKQLSERQSSVSHVYLEVTSKHFSKAKKMPVTYDNGFLFIHTDKPVYTPHQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEENDYTGIISFPDFKIPSNPKYGVWTIRAKYKEDFSTTGTAYFEIKEYVLPHFSISIEPKSNFIGYKDFTNFEITIRARYFYNKVVNEADVYITFGIRDNLEDNQKEMMQKAMQSTALINGMAQVTFNSETAVKELSYESLEDLNNKYLYIGVTIIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFVKPGIPYSVKVQVKDSFDHLVGGIPVTLSAKTLDANQEITDLESKKSVTRSSDGVASFVVNLPSEVTVLEFNIKTEDLDLPEENQASEDYRAVAYSSLSQSYLYIDWTENYKHLLVGAHLNIVVTPRSPYIDKITHYNFLILSKGKIVHFGTRDKLSDSAYQSINIPVTQDMVPSARLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLEVHLSPETDAYSPGQRVSLNMETELDSWVALTAVDSAIYGVQRTAKRPLERVFQTLEKGDLGCGAGGGRDNAEVFYLAGLTFLTNANADDTRENDEPCKEILRPKRMLKKKIEEEAAKYRNAWVKKCCYDGAHRNDDETCEQRAARIQAGPICIKAFKSCCAIASQFRADEHHKNMQLGRLHIKSLLPVTKPEIRSYFPESWLWEVHRVPKRNQLQFVLPDSLTTWEIQGVGISNSGICVADTLKAKVFKSVFLEMNIPYSVVRGEQVQLSGTVYNYRTSGIQFCVKMHPVEGICSSGTPVTDSQGRRFSKCVLQKIEGSSNHLVTFTVLPLEVGLHNLSFSLETSVGNEILVKTLRVVPEGVKRESYAGVTLDPQGVYGIISRRKEFPYRIPLNMVPKTKVKRTVSIKGLLIGEIMSAVLSQEGIDSLTRLPKGNAEAELMSVVPVFYVYHYLEAGHNWDIFSTNSLTQKQNLKTKLKEGMVSIMSFRNADYSYSMWKGGSASTWLTAFALRVLGQISKYVDQNQNSICNSLLWLLEKCQLENGSFKENSDYQPVKLQGTLPVEAREKTLYLTAFAVIGIRKAFDICPLEKISTAVSKADIFLHENALSSQSAFTLAIAAYALSLGDKAHPQFRAIVSALKRKAFVKGNPPIYRFWKDDLQQRDSFVPNTGTARMVETTAYALLTNLNLKDMNYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVRKLRLNMDVKVSYKNKGDLYHYKMSDKYFLGRPIEVPLNDDLVVLSTGQSSGLATVHVKTVVHKISTSEEVCSFHLKIETREIEAFGYSSSEYKRIVACASYKLSSEESSSGSSHAVMDISLPTGVNANPEDLKALVEQVDQLLTDYEIKDGHVILQLNSIPSNEFLCVRFRIIELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNTKLQKVCEGVTCKCIEADCGQMQAELDLTISAATRKETACKPEIAYAYKVEIVAVTEENAFVKYTATLLDIYKAGEAAAERDAEITFIKKTSCSNANLEKRKQYLIMGKEALQIKHNFRFKYVYPLDSSTWIEYWPTDSRCPSCQRFLANLDEFTEDIFLNGCENA", "length": 1677 }, "evidence": [ { "id": "A0A8V1AM71", "url": "https://omabrowser.org/oma/group/A0A8V1AM71/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P01031-1", "protein_name": "Complement C5", "gene_name": "C5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGIISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMATGMDSWVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANADDSQENDEPCKEILRPRRTLQKKIEEIAAKYKHSVVKKCCYDGACVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLVPRRKQLQFALPDSLTTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCSSCQAFLANLDEFAEDIFLNGC", "length": 1676 }, "evidence": [ { "id": "A0A8V1AM71", "url": "https://omabrowser.org/oma/group/A0A8V1AM71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P06684-1", "protein_name": "Complement C5", "gene_name": "C5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLWGILCLLIFLDKTWGQEQTYVISAPKILRVGSSENVVIQVHGYTEAFDATLSLKSYPDKKVTFSSGYVNLSPENKFQNAALLTLQPNQVPREESPVSHVYLEVVSKHFSKSKKIPITYNNGILFIHTDKPVYTPDQSVKIRVYSLGDDLKPAKRETVLTFIDPEGSEVDIVEENDYTGIISFPDFKIPSNPKYGVWTIKANYKKDFTTTGTAYFEIKEYVLPRFSVSIELERTFIGYKNFKNFEITVKARYFYNKVVPDAEVYAFFGLREDIKDEEKQMMHKATQAAKLVDGVAQISFDSETAVKELSYNSLEDLNNKYLYIAVTVTESSGGFSEEAEIPGVKYVLSPYTLNLVATPLFVKPGIPFSIKAQVKDSLEQAVGGVPVTLMAQTVDVNQETSDLETKRSITHDTDGVAVFVLNLPSNVTVLKFEIRTDDPELPEENQASKEYEAVAYSSLSQSYIYIAWTENYKPMLVGEYLNIMVTPKSPYIDKITHYNYLILSKGKIVQYGTREKLFSSTYQNINIPVTQNMVPSARLLVYYIVTGEQTAELVADAVWINIEEKCGNQLQVHLSPDEYVYSPGQTVSLDMVTEADSWVALSAVDRAVYKVQGNAKRAMQRVFQALDEKSDLGCGAGGGHDNADVFHLAGLTFLTNANADDSHYRDDSCKEILRSKRNLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVARVTIGPLCIRAFNECCTIANKIRKESPHKPVQLGRIHIKTLLPVMKADIRSYFPESWLWEIHRVPKRKQLQVTLPDSLTTWEIQGIGISDNGICVADTLKAKVFKEVFLEMNIPYSVVRGEQIQLKGTVYNYMTSGTKFCVKMSAVEGICTSGSSAASLHTSRPSRCVFQRIEGSSSHLVTFTLLPLEIGLHSINFSLETSFGKDILVKTLRVVPEGVKRESYAGVILDPKGIRGIVNRRKEFPYRIPLDLVPKTKVERILSVKGLLVGEFLSTVLSKEGINILTHLPKGSAEAELMSIAPVFYVFHYLEAGNHWNIFYPDTLSKRQSLEKKIKQGVVSVMSYRNADYSYSMWKGASASTWLTAFALRVLGQVAKYVKQDENSICNSLLWLVEKCQLENGSFKENSQYLPIKLQGTLPAEAQEKTLYLTAFSVIGIRKAVDICPTMKIHTALDKADSFLLENTLPSKSTFTLAIVAYALSLGDRTHPRFRLIVSALRKEAFVKGDPPIYRYWRDTLKRPDSSVPSSGTAGMVETTAYALLASLKLKDMNYANPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLLKQIHLDMDINVAYKHEGDFHKYKVTEKHFLGRPVEVSLNDDLVVSTGYSSGLATVYVKTVVHKISVSEEFCSFYLKIDTQDIEASSHFRLSDSGFKRIIACASYKPSKEESTSGSSHAVMDISLPTGIGANEEDLRALVEGVDQLLTDYQIKDGHVILQLNSIPSRDFLCVRFRIFELFQVGFLNPATFTVYEYHRPDKQCTMIYSISDTRLQKVCEGAACTCVEADCAQLQAEVDLAISADSRKEKACKPETAYAYKVRITSATEENVFVKYTATLLVTYKTGEAADENSEVTFIKKMSCTNANLVKGKQYLIMGKEVLQIKHNFSFKYIYPLDSSTWIEYWPTDTTCPSCQAFVENLNNFAEDLFLNSCE", "length": 1680 }, "evidence": [ { "id": "A0A8V1AM71", "url": "https://omabrowser.org/oma/group/A0A8V1AM71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P08650-1", "protein_name": "Complement C5", "gene_name": "C5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLWGLLCLLIFLDKTWGQEQTYVISAPKIFRVGSSENVVIQAHGYTEAFDATISLKSYPDKKVTYSSGYVNLSPENKFQNSALLTLPPKQFPRDENPVSHVYLEVVSMHFSKSKKIPITYDNGFLFIHTDKPVYTPDQSVKIRVYSLSDDLKPAKRETVLTFVDPEGTEVDIVEENDYTGIISFPDFKIPSNPKYGVWTIKAKYKKDFTTTGTAYFEVKEYVLPRFSVSIEPESNFIGYKNFKNFEITVKARYFYNKMVPDAEVYIFFGLREDIKEDEKQMMHKAMQAATLMDGAAQTCWLAETEVREINYNMFEDRNNNYSYIACTVTESSGGFSEEAEIPGIKYVLSPYTLNLVATPLFLKPGIPFSIKVQVKDSLEQLVGGVPVTLMAQTVNVNQETSDLEPKRSITHSADGVASFVVNLPSEVTSLKFEVKTDAPELPEENQASKEYEAVTYSSLSQSYIYIGWTENYKPMLVGEYLNIIVTPKSPYIDKITHYNYLILSKGKIVQYGTKEKLLYSSYQNINIPVTQDMVPSARLLVYYIVTGEQTAELVADAVWINIEEKCGNQLQVHLSPDKDVYSPGQTVSLDMVTEADSWVALSAVDSAVYGVRGKAKRAMQRVFQAFDDKSDLGCGAGGGRDNVDVFHLAGLTFLTNANADDSQYHDDSCKEILRPKRDLQLLHQKVEEQAAKYKHRVPKKCCYDGARENKYETCEQRVARVTIGPHCIRAFNECCTIADKIRKESHHKGMLLGRIQIKALLPVMKAEIRSYFPESWLWEVHRVPKRNQLQVALPDSLTTWEIQGIGISDNGICVADTLKAKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGTMFCVKMSAVEGICTPGSSAASPQTSRSSRCVRQRIEGSSSHLVTFSLLPLEIGLHSINFSLETSFGKEILVKTLRVVPEGIKRESYAGVTLDPRGVYGIVNRRKEFPYRIPLDLVPKTNVKRILSVKGLLIGEFLSTVLSKEGIDILTHLPKGSAEAELMSIVPVFYVFHYLEAGNHWNIFHPDTLARKQSLQKKIKEGLVSVMSYRNADYSYSMWKGASSSAWLTAFALRVLGQVNKYVKQDQYSICNSLLWLIEKCQLENGSFKENSQYLPIKLQGTLPAEAQENTLYLTAFSVIGIRKAIGICPTEKIYTALAKADSFLLERTLPSKSTFTLAIVAYALSLGDRTHPKFRSIVSALKREALVKGDPPIYRFWRDTLQRPDSSAPNSGTAGMVETTAYALLTSLNLKETSYVNPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLHLDMDINVSYKHKGDFYQYKVTEKNFLGRPVEVPLNDDLIVTTGYSSGLATVYVKTVVHKTSVAEEFCSFYLKIDTQEVEASSYLSYSDSGHKRIIACASYKPSKEESASGSSHAVMDILLPTGIGANQEDLRALVEGVDQLLTDYQIKDSHVILQLNSIPSRDFLCVRFRIFELFQVGFLNPATFTVYEYHRPDKQCTMIYSTSDTNLQRVCEGAACKCVEADCGQLQAELDLAISADTRKETACKPEIAYAYKVRITSATEENIFVKYTATLLDIYKTGEAAAEKDSEITFIKKISCTNANLVKGKQYLIMGKEALQIKHNFSFKYIYPLDSSTWIEYWPTDTTCPSCQAFVANLDEFAEDIFLNGCE", "length": 1681 }, "evidence": [ { "id": "A0A8V1AM71", "url": "https://omabrowser.org/oma/group/A0A8V1AM71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM71" } ], "pmid": "" }, { "name": "membrane attack complex", "id": "GO:0005579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AM71", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of vascular endothelial growth factor production", "id": "GO:0010575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010575", "evidence": [ { 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"https://alphafold.ebi.ac.uk/entry/A0A8V1AMB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AMB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHFVRQSRAALMMCCFLGSSSCLPTYVRISRSSDSTSFFASSLLALIKLKAMTSPRCCTSMLSCKQSLCRISSHWVVFKEGKCC", "length": 84, "header": "tr|A0A8V1AMB2-1|A0A8V1AMB2_CHICK Isoform 1 of Secreted protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AMB2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMB2/entry#A0A8V1AMB2-1", "sequence": { "sequence": "MHFVRQSRAALMMCCFLGSSSCLPTYVRISRSSDSTSFFASSLLALIKLKAMTSPRCCTSMLSCKQSLCRISSHWVVFKEGKCC", "length": 84, "header": "tr|A0A8V1AMB2-1|A0A8V1AMB2_CHICK Isoform 1 of Secreted protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1AMB2-1" }, "locus": { "chromosome": "19", "start_pos": 4950556, "end_pos": 4950305, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072059.1", "url": "https://www.ensembl.org/id/ENSGALT00010072059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044749.1", "url": "https://www.ensembl.org/id/ENSGALP00010044749.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "uniprot_ac": "A0A8V1AMC7", "uniprot_id": "A0A8V1AMC7_CHICK", "mass": { "chemical_mass": 27227.0, "monoisotopic_mass": 27227.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121107218", "type": "recommended", "evidence": [ { "id": "A0A8V1AMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7" } ] } ], "protein_names": [ { "name": "ODF3A protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AMC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121107218", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7", "locus": {} } ], "crossref": [ { "id": "A0A8V1AMC7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMC7", "url": "https://www.orthodb.org/?gene=A0A8V1AMC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255, "header": "tr|A0A8V1AMC7-1|A0A8V1AMC7_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN=LOC121107218 PE=4 SV=1 CANONICAL=A0A8V1AMC7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7/entry#A0A8V1AMC7-1", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255, "header": "tr|A0A8V1AMC7-1|A0A8V1AMC7_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN=LOC121107218 PE=4 SV=1 CANONICAL=A0A8V1AMC7-1" }, "locus": { "chromosome": "19", "start_pos": 324633, "end_pos": 321850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071281.1", "url": "https://www.ensembl.org/id/ENSGALT00010071281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043972.1", "url": "https://www.ensembl.org/id/ENSGALP00010043972.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 103, "start_aa": "Thr", "end_pos": 103, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr103", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A8V1AMC7", "url": "https://omabrowser.org/oma/group/A0A8V1AMC7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 103 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMD6-1", "uniprot_ac": "A0A8V1AMD6", "uniprot_id": "A0A8V1AMD6_CHICK", "mass": { "chemical_mass": 35267.0, "monoisotopic_mass": 35267.0 }, "refseq": {}, "gene_names": [ { "name": "LOC112529952", "type": "recommended", "evidence": [ { "id": "A0A8V1AMD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6" } ] } ], "protein_names": [ { "name": "Fibrinogen C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AMD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112529952", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6", "locus": {} } ], "crossref": [ { "id": "A0A8V1AMD6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMD6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMD6", "url": "https://www.orthodb.org/?gene=A0A8V1AMD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANX4", "url": "https://www.orthodb.org/?gene=A0A8V1ANX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF438", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF438", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AMD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSILTATTQGLSSPQCLLSPLDDWHPSVCSKAALFRAPSYAVPSGNFTQGAEHSRQRALQALLLAQALFSLQLCQAPRSLSSQAMFSAGQKGTRFDSHPQEKGGCVGQARSPHPLQRALQVPLPLRPHSSARQREPCAAAMVTQCLPLLASVLVLAAPGLSVPAQAQNTSKKTFSSTWTNTLKKDSWPKDCSEISAGSPSGVYVIQPSGLHPIVVYCEMNVTGGGWTVIQRNRYNTDITWAESWSTYKYGFGNVHSDYWLGTEYIHQIAKQKVYRGQVCHPGCLQQHQVRRVQPLQCGQRVPGLPAAAGLLLRDSGGCHGLGQSQ", "length": 326, "header": "tr|A0A8V1AMD6-1|A0A8V1AMD6_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112529952 PE=4 SV=1 CANONICAL=A0A8V1AMD6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6/entry#A0A8V1AMD6-1", "sequence": { "sequence": "MPSILTATTQGLSSPQCLLSPLDDWHPSVCSKAALFRAPSYAVPSGNFTQGAEHSRQRALQALLLAQALFSLQLCQAPRSLSSQAMFSAGQKGTRFDSHPQEKGGCVGQARSPHPLQRALQVPLPLRPHSSARQREPCAAAMVTQCLPLLASVLVLAAPGLSVPAQAQNTSKKTFSSTWTNTLKKDSWPKDCSEISAGSPSGVYVIQPSGLHPIVVYCEMNVTGGGWTVIQRNRYNTDITWAESWSTYKYGFGNVHSDYWLGTEYIHQIAKQKVYRGQVCHPGCLQQHQVRRVQPLQCGQRVPGLPAAAGLLLRDSGGCHGLGQSQ", "length": 326, "header": "tr|A0A8V1AMD6-1|A0A8V1AMD6_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112529952 PE=4 SV=1 CANONICAL=A0A8V1AMD6-1" }, "locus": { "chromosome": "19", "start_pos": 527852, "end_pos": 526318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071296.1", "url": "https://www.ensembl.org/id/ENSGALT00010071296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043987.1", "url": "https://www.ensembl.org/id/ENSGALP00010043987.1" } ] } }, { "isoform_ac": "A0A8V1ANX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6/entry#A0A8V1ANX4-1", "sequence": { "sequence": "PCLVRGFGDGERASCSPLGQRSGGLRLPVWHRAQLTQCLPLLASVLVLAAPGLSVPAQAQNTSKKTFSSTWTNTLKKDSWPKDCSEISAGSPSGVYVIQPSGLHPIVVYCEMNVTGGGWTVIQRNRYNTDITWAESWSTYKYGFGNVHSDYWLGTEYIHQIAKQKVYRGQVCHPGCLQQHQVRRVQPLQCGQRVPGLPAAAGLLLRDSGGCHGLGQSQ", "length": 218, "header": "tr|A0A8V1ANX4-1|A0A8V1ANX4_CHICK Computationally mapped isoform of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112529952 PE=4 SV=1 CANONICAL=A0A8V1AMD6-1" }, "locus": { "chromosome": "19", "start_pos": 527202, "end_pos": 526318, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071294.1", "url": "https://www.ensembl.org/id/ENSGALT00010071294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043985.1", "url": "https://www.ensembl.org/id/ENSGALP00010043985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMD6" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 183, "end_pos": 276, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AME4-1", "uniprot_ac": "A0A8V1AME4", "uniprot_id": "A0A8V1AME4_CHICK", "mass": { "chemical_mass": 108781.0, "monoisotopic_mass": 108781.0 }, "refseq": { "ac": "XP_040506464", "name": "unconventional myosin-XIX isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506464" }, "gene_names": [ { "name": "MYO19", "type": "recommended", "evidence": [ { "id": "A0A8V1AME4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ] }, { "name": "MYO19", "type": "synonym", "evidence": [ { "id": "XP_040506464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506464" } ] } ], "protein_names": [ { "name": "Unconventional myosin-XIX", "type": "recommended", "evidence": [ { "id": "A0A8V1AME4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4/entry#names_and_taxonomy" } ] }, { "name": "unconventional myosin-XIX isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040506464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506464" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506464" } ] }, { "annotation": "Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments. Required for mitochondrial inheritance during mitosis. May be involved in mitochondrial transport or positioning.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4#function" }, { "database": "UniProtKB", "id": "ARBA00054433", "url": "https://www.uniprot.org/uniprotkb/ARBA00054433#function" }, { "database": "UniProtKB", "id": "A0A8V1AB53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB53#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYO19", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4", "locus": { "chromosome": "19", "start_pos": 8611184, "end_pos": 8627675, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029181", "url": "https://www.ensembl.org/id/ENSGALG00010029181" } ] } } ], "crossref": [ { "id": "A0A8V1AME4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AME4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417649", "url": "https://www.ncbi.nlm.nih.gov/gene/417649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CSLETTW", "url": "https://omabrowser.org/oma/group/CSLETTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AB53", "url": "https://www.orthodb.org/?gene=A0A8V1AB53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AME4", "url": "https://www.orthodb.org/?gene=A0A8V1AME4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13140:SF289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13140:SF289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013419", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013419", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013425", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013425", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040506464", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AB53", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AB53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKQVNCQKEDSVTQNDMNESFEEEVRAFLSDEEQLHLFDDLTKVNPVTTTTVLKCLQARYTVNLFYTNAGCSLVALNPFQPISCLYSPELMREYHVAVRPQDLKPHIFAVAEQTYRNVQSQINPINQSIIVSGESGAGKTWTSRCLMKFYASVAASATSPKGNEAVERIEKRVLDSNPIMEAFGNACTLRNNNSSRFGKYIQLHLDRFHHLSSASIQTFLLEKTRVAYQAPNERNFHIFYQITKGATAEERLAWNLPEGAHYRWLPNSERNLEEDCFEVTRDAMFHLGIDHSTQNNIFKVLSGLLHLGNIQFSNPVDESQPCELEDKAKDFVKTAGDLLKIPVEELLQSLRIRTITAGKQQQVVKKPCSRTECDTRRDCLAKVIYAKLFDWLVLVINESIYADTSLWTSFIGLLDVYGFEAFPENNLEQLCINYANEKLQQHFVAHYLKAQQEEYASEGLQWSFINYQDNQSCLDLIEGNPLSIFSLLNEECRLNRSSNPDLFQTRIEKALSDNQCLSRDKFSKKPNFIISHYAGKVCYQLAAMVEKNKDPIPPELVHVLQNSKDTLLQKLFPIAETNQNNTKTQNRAAVVTVVSKFKSSLENLMQILNSTEPHYIRCIKPNADCQAMTFRKEEVLSQLQACGIVEAITISAAGFPIRISFQSFTDRYEILRKSRRSSKNNACDKSNYHTAKKKGETAAVDDNKASHSVIAEILQNVVTGQSAAEPTGKGSESTSVYCGKTKVFMANSVLEQLEARRAEVLNKKAFCIQCFWRRFKQKKLAKERRCATLIQAAIRSWLAKNRFQRMRRAADVIKRGWRKWKAKMAALAAAELDENDEKTPFSAMSAKSPCSLETAWPLSAIIQFWPLGLVLSAAPVTIVGLRRELSLLACLKVLQGIGCYKMESSFLGCGITSVRALPQGSVRFHCKKSPLHYANVSPHTAAYSTTGFNQILLDRKELLPT", "length": 962, "header": "tr|A0A8V1AME4-1|A0A8V1AME4_CHICK Isoform 1 of Unconventional myosin-XIX OS=Gallus gallus OX=9031 GN=MYO19 PE=3 SV=1 CANONICAL=A0A8V1AME4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AB53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4/entry#A0A8V1AB53-1", "sequence": { "sequence": "MPKQVNCQKEDSVTQNDMNESFEEEVRAFLSDEEQLHLFDDLTKVNPVTTTTVLKCLQARYTVNLFYTNAGCSLVALNPFQPISCLYSPELMREYHVAVRPQDLKPHIFAVAEQTYRNVQSQINPINQSIIVSGESGAGKTWTSRCLMKFYASVAASATSPKGNEAVERIEKRVLDSNPIMEAFGNACTLRNNNSSRFGKYIQLHLDRFHHLSSASIQTFLLEKTRVAYQAPNERNFHIFYQITKGATAEERLAWNLPEGAHYRWLPNSERNLEEDCFEVTRDAMFHLGIDHSTQNNIFKVLSGLLHLGNIQFSNPVDESQPCELEDKAKDFVKTAGDLLKIPVEELLQSLRIRTITAGKQQQVVKKPCSRTECDTRRDCLAKVIYAKLFDWLVLVINESIYADTSLWTSFIGLLDVYGFEAFPENNLEQLCINYANEKLQQHFVAHYLKAQQEEYASEGLQWSFINYQDNQSCLDLIEGNPLSIFSLLNEECRLNRSSNPDLFQTRIEKALSDNQCLSRDKFSKKPNFIISHYAGKVCYQLAAMVEKNKDPIPPELVHVLQNSKDTLLQKLFPIAETNQNNTKTQNRAAVVTVVSKFKSSLENLMQILNSTEPHYIRCIKPNADCQAMTFRKEEVLSQLQACGIVEAITISAAGFPIRISFQSFTDRYEILRKSRRSSKNNACDKSNYHTAKKKGETAAVDDNKASHSVIAEILQNVVTGQSAAEPTGKGSESTSVYCGKTKVFMANSVLEQLEARRAEVLNKKAFCIQCFWRRFKQKKLAKERRCATLIQAAIRSWLAKNRFQRMRRAADVIKRGWRKWKAKMAALAAAELDENDEKTPFSAMSAKSPCSLETAWPLSAIIQFWPLGLVLSAAPVTIVGLRRELSLLACLKVLQGIGCYKMESSFLGCGITSVRALPQVTQHN", "length": 925, "header": "tr|A0A8V1AB53-1|A0A8V1AB53_CHICK Computationally mapped isoform of Unconventional myosin-XIX OS=Gallus gallus OX=9031 GN=MYO19 PE=3 SV=1 CANONICAL=A0A8V1AME4-1" }, "locus": { "chromosome": "19", "start_pos": 8627223, "end_pos": 8612271, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070514.1", "url": "https://www.ensembl.org/id/ENSGALT00010070514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043205.1", "url": "https://www.ensembl.org/id/ENSGALP00010043205.1" } ] } }, { "isoform_ac": "A0A8V1AME4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4/entry#A0A8V1AME4-1", "sequence": { "sequence": "MPKQVNCQKEDSVTQNDMNESFEEEVRAFLSDEEQLHLFDDLTKVNPVTTTTVLKCLQARYTVNLFYTNAGCSLVALNPFQPISCLYSPELMREYHVAVRPQDLKPHIFAVAEQTYRNVQSQINPINQSIIVSGESGAGKTWTSRCLMKFYASVAASATSPKGNEAVERIEKRVLDSNPIMEAFGNACTLRNNNSSRFGKYIQLHLDRFHHLSSASIQTFLLEKTRVAYQAPNERNFHIFYQITKGATAEERLAWNLPEGAHYRWLPNSERNLEEDCFEVTRDAMFHLGIDHSTQNNIFKVLSGLLHLGNIQFSNPVDESQPCELEDKAKDFVKTAGDLLKIPVEELLQSLRIRTITAGKQQQVVKKPCSRTECDTRRDCLAKVIYAKLFDWLVLVINESIYADTSLWTSFIGLLDVYGFEAFPENNLEQLCINYANEKLQQHFVAHYLKAQQEEYASEGLQWSFINYQDNQSCLDLIEGNPLSIFSLLNEECRLNRSSNPDLFQTRIEKALSDNQCLSRDKFSKKPNFIISHYAGKVCYQLAAMVEKNKDPIPPELVHVLQNSKDTLLQKLFPIAETNQNNTKTQNRAAVVTVVSKFKSSLENLMQILNSTEPHYIRCIKPNADCQAMTFRKEEVLSQLQACGIVEAITISAAGFPIRISFQSFTDRYEILRKSRRSSKNNACDKSNYHTAKKKGETAAVDDNKASHSVIAEILQNVVTGQSAAEPTGKGSESTSVYCGKTKVFMANSVLEQLEARRAEVLNKKAFCIQCFWRRFKQKKLAKERRCATLIQAAIRSWLAKNRFQRMRRAADVIKRGWRKWKAKMAALAAAELDENDEKTPFSAMSAKSPCSLETAWPLSAIIQFWPLGLVLSAAPVTIVGLRRELSLLACLKVLQGIGCYKMESSFLGCGITSVRALPQGSVRFHCKKSPLHYANVSPHTAAYSTTGFNQILLDRKELLPT", "length": 962, "header": "tr|A0A8V1AME4-1|A0A8V1AME4_CHICK Isoform 1 of Unconventional myosin-XIX OS=Gallus gallus OX=9031 GN=MYO19 PE=3 SV=1 CANONICAL=A0A8V1AME4-1" }, "locus": { "chromosome": "19", "start_pos": 8627223, "end_pos": 8611835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070515.1", "url": "https://www.ensembl.org/id/ENSGALT00010070515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043206.1", "url": "https://www.ensembl.org/id/ENSGALP00010043206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9013419", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013419", "resource": "Reactome", "description": "RHOT2 GTPase cycle" }, { "id": "R-GGA-9013425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013425", "resource": "Reactome", "description": "RHOT1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GBR3-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLQQVNGHSSGTDAEGKASLKGDLQQFLDGEAPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKPIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIKPINQSIVVSGESGAGKTWTSRCLMKFYAVVASSSASCENHKMAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASNERNFHIFYQICKGATKDERLQWYLPEGAAFSWLPNPENNLEEDCFELTREAMLHLGIDTPTQNNIFKDFKPHRTISKELAITVLAGLLHLGNVHFTDSEDEAQPCQLMDGTKVSVRTSASLLHLQEDLLLETMQIRTIKAGKQQQVFRKPCSRAECDTRRDCLAKLIYARLFNWLVSVINSSICADSSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLKAQQEEYAVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQSRIESALAGKPCLGHNKLSREPSFVVVHFAGPVRYHTEGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPDNPEEKTQEELSGQSRVPALTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQSKPQTFLQKEVLSQLEACGLVETIHISAAGFPIRVSHQNFVERYKLLRRLRPRTSSGLQGLCPARGPSEQPLCAKDATLQPPLQDILHALPALIQTATTPSDPAETTQVPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHQLQKQKKQRQAAVLIQAAIRSWLTRKHIQRLHIAATVIKRAWHKWRIRMACLAAKELDGMEEKPMTQTPSSLSSSLPPAHTNLLGAIIHLWPLGLVLANSAVGVRGFQRKLVAYACLRLPSSSPSNNIQTAQDQAGITSIRALPQGSIKFHCRKSPLQYADICPEPSASSVSGFNQILLERNRPVQV", "length": 977 }, "evidence": [ { "id": "A0A8V1AME4", "url": "https://omabrowser.org/oma/group/A0A8V1AME4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3Z8I9-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHQQVNGHSLGSDTQGRTSLKGDLREFLGGEVPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIEPINQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCENHKMAERIEERILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQAASERNFHIFYQICKGATKEERLQWCLPEGTAFSWLPNPESSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEAQPCQLMDGTKGSVRTSALLLQLPDNMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADFSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSREPSFVVMHFAGPVRYCTAGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHKTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFMERYKLLTRLRPRTSSGLRSLCPAKGSSEQPLCAKEATLQPLLQDILHALPALIQTATTPSDPAKTAQIPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVIIQAAFRSWLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKLMPQAPGTLRSSLSPAHTRFLGAIIHLWPLGLVLANSADGMRGFQRKLVAHACLRLPASGPSNKVQTPQQDQAGITSIRALPQGSIKFHCRKSPLQYADICPDPSASNVTGFNQILLLERHRPVQV", "length": 964 }, "evidence": [ { "id": "A0A8V1AME4", "url": "https://omabrowser.org/oma/group/A0A8V1AME4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S203-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "MYO19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQQVNGHGSGSDAHSGGESLREELQEFLGGEALLHQLDDLTQVNPVTLETVLRCLQARYSADMFYTNAGCTLVALNPFKPVPQLYSTELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLMEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSRESHKIAERIEQRILNSNPVMEAFGNAGTLRNNNSSRFGKFIQLQLNRTQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASADERLQWHLPEGATFSWLPNPERTLEEDCFEVTREAMLHLGIDAPTQNNIFQALAGLLHLGNIQFADSRDEAQPCQLMDSAKCSARTSASLLRLPEDLLLETLQIRTIRAGRQQQVFQKPCSRAECDTRRDCLAKLVYARLFDWLVSVINSSICADPDSWTTFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAAEGLQWSFVNYQDNQTCLDLIEGSPISICSLMNEECRLNRPSSAAQLQTRIESALAGSPCLGHDKLSQEPSFIVVHYAGPVRYHTAGLVEKNKDPVPPELTRLLQQSQDPLLKVLFPPDPEEKSQEEPSGQSRTPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQMFHPEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYELLRRLRPGTAPSQSADEGRSERSPRAEQATLQALFQDILHTLPALAQAAATPGDRAEATPAPVHCGRTKVFMTDSTLELLERGRAQVLEQCARCIQGGWRRHQRRKQERQRQAAVLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMAFLASKELDGVEEKHSSQAPRSPSSLSLPQAQSRLPGGATRLWPLGLVLANAAVGVRGFQRKLVVFACLQLPVGAPSSYTIQTAQDQAGVMSIRALPQGSIRFRCRKSPLRYADICPQPSPDSVTGFNQILLERHKLGHV", "length": 962 }, "evidence": [ { "id": "A0A8V1AME4", "url": "https://omabrowser.org/oma/group/A0A8V1AME4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5SV80-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQQVNGHSLGSDAEGRASLKGDLREFLGGEIPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHVPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCENHKIAERIEQRILNSNPVMEAFGNACTLRNSNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGATKDERLQWHLPEGTAFSWLPNPESSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEALPCQVMDDTKVSVRTSALLLQLPEKMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADSKSWTAFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSREPSFVVVHFAGPVRYHTAGLVEKNKDPVPPELTELLQQSQDPLLTMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHNTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFIERYKLLRRLGPRMSSGLGGLEPAEGSSEQPLCAKEATLQPLLQDILHALPALIQTAATPSDPAKNTQIPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVLIQAAFRSWLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKPMPQAPGTLRSSMSPAHTRFLGAIIHLWPLGLVLANSADGVRGFQRKLVAHACLRLPSDRPSNKVQTPQQDQAGITSIRALPQGSIKFHCRKSPLQYADICPDPSASCVTGFNQILLESHRPVQV", "length": 963 }, "evidence": [ { "id": "A0A8V1AME4", "url": "https://omabrowser.org/oma/group/A0A8V1AME4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96H55-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "MYO19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAVEGLEWSFINYQDNQPCLDLIEGSPISICSLINEECRLNRPSSAAQLQTRIETALAGSPCLGHNKLSREPSFIVVHYAGPVRYHTAGLVEKNKDPIPPELTRLLQQSQDPLLMGLFPTNPKEKTQEEPPGQSRAPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQTFLQEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAIIRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQGSIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG", "length": 970 }, "evidence": [ { "id": "A0A8V1AME4", "url": "https://omabrowser.org/oma/group/A0A8V1AME4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of mitochondrial fission", "id": "GO:0090140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "myosin light chain binding", "id": "GO:0032027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "plus-end directed microfilament motor activity", "id": "GO:0060002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AME4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME4" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 759, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 936, "end_pos": 938 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AME7-1", "uniprot_ac": "A0A8V1AME7", "uniprot_id": "A0A8V1AME7_CHICK", "mass": { "chemical_mass": 254164.0, "monoisotopic_mass": 254164.0 }, "refseq": { "ac": "XP_040543168", "name": "protein KIAA0100 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543168" }, "gene_names": [ { "name": "KIAA0100", "type": "recommended", "evidence": [ { "id": "A0A8V1AME7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7" } ] }, { "name": "KIAA0100", "type": "synonym", "evidence": [ { "id": "XP_040543168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543168" } ] } ], "protein_names": [ { "name": "Bridge-like lipid transfer protein family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AME7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7/entry#names_and_taxonomy" } ] }, { "name": "protein KIAA0100 homolog", "type": "synonym", "evidence": [ { "id": "XP_040543168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543168" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052591.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040543168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543168" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA0100", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7", "locus": {} } ], "crossref": [ { "id": "417573", "url": "https://www.ncbi.nlm.nih.gov/gene/417573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417573", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417573", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WASFETK", "url": "https://omabrowser.org/oma/group/WASFETK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AME7", "url": "https://www.orthodb.org/?gene=A0A8V1AME7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANY4", "url": "https://www.orthodb.org/?gene=A0A8V1ANY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15678:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15678:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040543168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AME7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLPPGLSLPLPAALLGLGLVLLLAGLLARWLACRLAVTWCRQKLQAELKIGSFGFFWAQNISLTFQREQQTVEIDNIWISSKLSRELPRYFELCFGEVRIRTDLQKSHGLQSSFPEAPKEADDGKNKADLALKPSLLRLLSQLFSIHMDSINIMVLHVATSESLWHIQASKTRLLLNGDGKSLNCEVNLTKVNSKVLRSSQLDDTCLAELALALSISLEISSKRRLVGVRLSVRTLQAELHEGLFCSPLLHRVIARAPQPSPDSAESLKSPSLLSRDTLQLIPKRVEVKLESTSVVLSMNSQKRHLTWSLKLLQFLYQREEEQIPLRNFTPTSDLDQMSVDLHLEDGLLLSQSRQRIVCLNSLKTSVQVTAIDLSAAVLLNTCIIHYRHQEFSHWLGLLAQEHRHHSAPVPSQGHKGRCYPQIIAPIILSASLSNVNVSVQLGDTPPFALGFNSISADYQHLRPQSVHQRAMLAVDHLCWRVGNDSHIQRAPHPPNMHVWGEALILDSFNLQGSYNQPLGMSSAQSDTLFLDCTIRGLQVESSDTCTECLARVLPLFCPQPSEAELAQQLSSAQSEPWILLWKVDLKVEDVNLFTLSAVVGALELRLDTLTVLGSAESCTVSVQGMVLALVKSITEKMQPCCKAPAIPNPVANLSMLSITYHSSIRSLEVQCGEGLAVLWSPPDHMHLYHHTLATLQCLEALRSAIGHGTPPSLTPQSPASPMATPTETLEPLQPDGAPPKRLLSLSLELSSAKVTAFVSEANYISLAAERTSVSWHGGALHGYCPELAAGFDGHSIFSFKEVEVKLLPELEEVILHRCAFPTLHTLRNRGWAFSFASVTIEFPYQYDFSRTLDAAVGVQKWLKGLHRRGRPAGTALPPDLLLKVTHFSWVFLDDVFEVKLRDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLEKKNIEIYIQRSRRLYANTPMRRALLTWTLSHLELVAMADESFHGTERVVEQMRDIDSVSPFPPEGLEMVTQWCRMMKGSIGSFFVRIRDYPRYLFEIRNWQLSGRLIGAEQCGQACSRRRQVLKLGLPWGDATVERNMPPLKFYHDFHSEISQYTIVWGPCWDPAWTLIGQCVDLLTKPSEDPSAPLSWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGNLDINVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHGVVLRSPEFLPEVPVGQQYDSYRAFRSENLNLSIRMDLTRLSEEHSQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNMKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQVECCQGHIFTRGTQRLIPQAGTVMRRLISEWSITQMVSDLSQVTVHLMASTCDENADHRLDTLVKKTHLLSLSSLTYQRHSNRTAEEELPLRDGDDGFHTHQLHLVDLRASWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDTQLQAKKLKRGPLSAHSAPAKVTAPITSGRSERASSGGAYMLQKLIEETDKFVVFTEEESGASEQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEREHGQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVSTTTDWNQPSEAQQTQQVQRIISRCSCRMYYISYSHDIDPELATQIKPPETPANQEKEDLLKKQEGAVDTFTLIHHDLEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSNVKSLQDDSKNESLLDLNHKLQQQLSQEKADLQLESEELNILIRCFKDFQLQRANKMELRKQPEDVSVARRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWVTMNNLLPNAVYKVVLRPQSSCQSGRQLALRIFSKVRPPVGGISIKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRNVEEEEVGDEEDKSKLVTTGIPVVKPRQLIGADDSLGPGKGVTQGLNRTSGVRRSFRKAPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKPAAGAEARGKLENKSDGTIQQQEEDEKARLLIGLSVGEKNPSKKSIFGRRK", "length": 2245, "header": "tr|A0A8V1AME7-1|A0A8V1AME7_CHICK Isoform 1 of Bridge-like lipid transfer protein family member 2 OS=Gallus gallus OX=9031 GN=KIAA0100 PE=1 SV=1 CANONICAL=A0A8V1AME7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AME7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7/entry#A0A8V1AME7-1", "sequence": { "sequence": "MLLPPGLSLPLPAALLGLGLVLLLAGLLARWLACRLAVTWCRQKLQAELKIGSFGFFWAQNISLTFQREQQTVEIDNIWISSKLSRELPRYFELCFGEVRIRTDLQKSHGLQSSFPEAPKEADDGKNKADLALKPSLLRLLSQLFSIHMDSINIMVLHVATSESLWHIQASKTRLLLNGDGKSLNCEVNLTKVNSKVLRSSQLDDTCLAELALALSISLEISSKRRLVGVRLSVRTLQAELHEGLFCSPLLHRVIARAPQPSPDSAESLKSPSLLSRDTLQLIPKRVEVKLESTSVVLSMNSQKRHLTWSLKLLQFLYQREEEQIPLRNFTPTSDLDQMSVDLHLEDGLLLSQSRQRIVCLNSLKTSVQVTAIDLSAAVLLNTCIIHYRHQEFSHWLGLLAQEHRHHSAPVPSQGHKGRCYPQIIAPIILSASLSNVNVSVQLGDTPPFALGFNSISADYQHLRPQSVHQRAMLAVDHLCWRVGNDSHIQRAPHPPNMHVWGEALILDSFNLQGSYNQPLGMSSAQSDTLFLDCTIRGLQVESSDTCTECLARVLPLFCPQPSEAELAQQLSSAQSEPWILLWKVDLKVEDVNLFTLSAVVGALELRLDTLTVLGSAESCTVSVQGMVLALVKSITEKMQPCCKAPAIPNPVANLSMLSITYHSSIRSLEVQCGEGLAVLWSPPDHMHLYHHTLATLQCLEALRSAIGHGTPPSLTPQSPASPMATPTETLEPLQPDGAPPKRLLSLSLELSSAKVTAFVSEANYISLAAERTSVSWHGGALHGYCPELAAGFDGHSIFSFKEVEVKLLPELEEVILHRCAFPTLHTLRNRGWAFSFASVTIEFPYQYDFSRTLDAAVGVQKWLKGLHRRGRPAGTALPPDLLLKVTHFSWVFLDDVFEVKLRDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLEKKNIEIYIQRSRRLYANTPMRRALLTWTLSHLELVAMADESFHGTERVVEQMRDIDSVSPFPPEGLEMVTQWCRMMKGSIGSFFVRIRDYPRYLFEIRNWQLSGRLIGAEQCGQACSRRRQVLKLGLPWGDATVERNMPPLKFYHDFHSEISQYTIVWGPCWDPAWTLIGQCVDLLTKPSEDPSAPLSWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGNLDINVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHGVVLRSPEFLPEVPVGQQYDSYRAFRSENLNLSIRMDLTRLSEEHSQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNMKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQVECCQGHIFTRGTQRLIPQAGTVMRRLISEWSITQMVSDLSQVTVHLMASTCDENADHRLDTLVKKTHLLSLSSLTYQRHSNRTAEEELPLRDGDDGFHTHQLHLVDLRASWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDTQLQAKKLKRGPLSAHSAPAKVTAPITSGRSERASSGGAYMLQKLIEETDKFVVFTEEESGASEQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEREHGQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVSTTTDWNQPSEAQQTQQVQRIISRCSCRMYYISYSHDIDPELATQIKPPETPANQEKEDLLKKQEGAVDTFTLIHHDLEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSNVKSLQDDSKNESLLDLNHKLQQQLSQEKADLQLESEELNILIRCFKDFQLQRANKMELRKQPEDVSVARRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWVTMNNLLPNAVYKVVLRPQSSCQSGRQLALRIFSKVRPPVGGISIKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRNVEEEEVGDEEDKSKLVTTGIPVVKPRQLIGADDSLGPGKGVTQGLNRTSGVRRSFRKAPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKPAAGAEARGKLENKSDGTIQQQEEDEKARLLIGLSVGEKNPSKKSIFGRRK", "length": 2245, "header": "tr|A0A8V1AME7-1|A0A8V1AME7_CHICK Isoform 1 of Bridge-like lipid transfer protein family member 2 OS=Gallus gallus OX=9031 GN=KIAA0100 PE=1 SV=1 CANONICAL=A0A8V1AME7-1" }, "locus": { "chromosome": "19", "start_pos": 6250929, "end_pos": 6238203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072325.1", "url": "https://www.ensembl.org/id/ENSGALT00010072325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044792.1", "url": "https://www.ensembl.org/id/ENSGALP00010044792.1" } ] } }, { "isoform_ac": "A0A8V1ANY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7/entry#A0A8V1ANY4-1", "sequence": { "sequence": "MDSINIMVLHVATSESLWHIQASKTRLLLNGDGKSLNCEVNLTKVNSKVLRSSQLDDTCLAELALALSISLEISSKRRLVGVRLSVRTLQAELHEGLFCSPLLHRVIARAPQPSPDSAESLKSPSLLSRDTLQLIPKRVEVKLESTSVVLSMNSQKRHLTWSLKLLQFLYQREEEQIPLRNFTPTSDLDQMSVDLHLEDGLLLSQSRQRIVCLNSLKTSVQVTAIDLSAAVLLNTCIIHYRHQEFSHWLGLLAQEHRHHSAPVPSQGHKGRCYPQIIAPIILSASLSNVNVSVQLGDTPPFALGFNSISADYQHLRPQSVHQRAMLAVDHLCWRVGNDSHIQRAPHPPNMHVWGEALILDSFNLQGSYNQPLGMSSAQSDTLFLDCTIRGLQVESSDTCTECLARVLPLFCPQPSEAELAQQLSSAQSEPWILLWKVDLKVEDVNLFTLSAVVGALELRLDTLTVLGSAESCTVSVQGMVLALVKSITEKMQPCCKAPAIPNPVANLSMLSITYHSSIRSLEVQCGEGLAVLWSPPDHMHLYHHTLATLQCLEALRSAIGHGTPPSLTPQSPASPMATPTETLEPLQPDGAPPKRLLSLSLELSSAKVTAFVSEANYISLAAERTSVSWHGGALHGYCPELAAGFDGHSIFSFKEVEVKLLPELEEVILHRCAFPTLHTLRNRGWAFSFASVTIEFPYQYDFSRTLDAAVGVQKWLKGLHRRGRPAGTALPPDLLLKVTHFSWVFLDDVFEVKLRDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLEKKNIEIYIQRSRRLYANTPMRRALLTWTLSHLELVAMADESFHGTERVVEQMRDIDSVSPFPPEGLEMVTQWCRMMKGSIGSFFVRIRDYPRYLFEIRNWQLSGRLIGAEQCGQACSRRRQVLKLGLPWGDATVERNMPPLKFYHDFHSEISQYTIVWGPCWDPAWTLIGQCVDLLTKPSEDPSAPLSWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGNLDINVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHGVVLRSPEFLPEVPVGQQYDSYRAFRSENLNLSIRMDLTRLSEEHSQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNMKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQVECCQGHIFTRGTQRLIPQAGTVMRRLISEWSITQMVSDLSQVTVHLMASTCDENADHRLDTLVKKTHLLSLSSLTYQRHSNRTAEEELPLRDGDDGFHTHQLHLVDLRASWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDTQLQAKKLKRGPLSAHSAPAKVTAPITSGRSERASSGGAYMLQKLIEETDKFVVFTEEESGASEQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEREHGQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVSTTTDWNQPSEAQQTQQVQRIISRCSCRMYYISYSHDIDPELATQIKPPETPANQEKEDLLKKQEGAVDTFTLIHHDLEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSNVKSLQDDSKNESLLDLNHKLQQQLSQEKADLQLESEELNILIRCFKDFQLQRANKMELRKQPEDVSVARRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVVLRPQSSCQSGRQLALRIFSKVRPPVGGISIKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRNVEEEEVGDEEDKSKLVTTGIPVVKPRQLIGADDSLGPGKGVTQGLNRTSGVRRSFRKAPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKPAAGAEARGKLENKSDGTIQQQEEDEKARLLIGLSVGEKNPSKKSIFGRRK", "length": 2068, "header": "tr|A0A8V1ANY4-1|A0A8V1ANY4_CHICK Computationally mapped isoform of Bridge-like lipid transfer protein family member 2 OS=Gallus gallus OX=9031 GN=KIAA0100 PE=1 SV=1 CANONICAL=A0A8V1AME7-1" }, "locus": { "chromosome": "19", "start_pos": 6249135, "end_pos": 6238203, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072324.1", "url": "https://www.ensembl.org/id/ENSGALT00010072324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044791.1", "url": "https://www.ensembl.org/id/ENSGALP00010044791.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417573", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AND3-1", "protein_name": "KIAA0100", "gene_name": "KIAA0100", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLFFSALLALLLVALIALFLGRWLVVRLATSWCQRKLKAELKIGSFFWIQNVSLKFQQHQQTVEIDSLRISSKLLSHDLPHYVALCFGEVRIRTDLQKVSGLFAPFSQNAGVHQKELSFSPSLLKIFCQLFSIHVDSVNIMVLKVATSESLWHIQIRDCSFLLDSDGKRLKCGVSLSQINSKVLKSGQLEDTCLAELSLALELCLEVGISSWQLKAITVDVWTLHAELHEGLFHSQLLRQGPGLAPKPVPGSEVTENLAEPTLPGLYLLQQLPDQVKVKMEITSVVLSMNSQKRHLNWTLKLLHFLYHRDEDQLPLRSFTANSDLAQMSTELLLKDGLLLSQSRQRIVCLNSLKASVQVTTIDLSASLVLNTCIIHYRHQEFSHWLHMLTPEAQESSSSVLKQRKKRTFPQILAPIIFSTSISNVNVSIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEASDTCAQCLSRILSLMGRQSGQSAVPRESSFGDLVSLLWKVDLKVEDMNLFTLSSLVGASEIRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRALEVQCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATLFPETVPLLALETPGTASEPEGCPPESSPPKRLLNLTLEVSTAKLTAFVAENKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFNFKEVEVQLLPELEEMILHRNPFPVLQTLRNRVWFLSLGSVSVEFPYQYDFSRTLDEAVGVQKWLKGLHRGTHAQASPSPAPLPPDLLLKVQHFSWVFLDDIFEVKLRDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLEHKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPERVVEQVRELDPGSPFPAEGMDLVIQWCRMLKCSVKTFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWGDVAVERNMPPLKFYHDFHSEIFQYTVVWGPCWDPAWTLIGQSVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWNHLSFHWKPGQFVFKGDLDVNVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHGVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIKMDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVTQMVSDLSQVTVYLMASPTEENADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSTRVGDPAFHTHQLHLVDLRASWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAKKPKQNAGTSAPAPPPVSTPSFSGQPDKGSSGGTYMLQKLIEETDRFVVFTEEESGVSDQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVHENQEKEDLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQQANKMELRKQQEDVSVVRRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRIMGFFFPGRSVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAAPLGPGKGVAQGLNRSSGVRRSFRKAPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLKLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKPATGAEVRGKLETKSDLNMQQQEEEEKARLLIGLSVGNKNPGKKSIFGRRK", "length": 2233 }, "evidence": [ { "id": "A0A8V1AME7", "url": "https://omabrowser.org/oma/group/A0A8V1AME7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SBY1-1", "protein_name": "KIAA0100", "gene_name": "KIAA0100", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLFFSALLALLLLGLSALFLVRWLVVRLATKWCQQKLQAELKIGSFFWIQNVSLKFQQHQQTVEIDSLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVSSLFAPFSQSTGAHQKELAFSPSLLKICQLFSIHVDSINIMVLKVATSESLWHIQIRESSFLLDSDGKRLKCEVSLSQINSKVLKSGQLEDTCLAELSLALKLCLEVGISSGQLKAITVDVWTLHAELHEGLFHSQLLRQGTGLAPKPLPGSELTEDLAEPTLPGLYLLQQLPDQVKVKMEITSVVLSMNSQKRHLNWTLKLLHFLYHRDEDQLPLRSFTANSDVAQMSTELLLKDGLLLSQSRQRIVCLNCLKANVQVTTIDLSASLVLNTCIIHYRHQEFSHWLHMLALETQESSSSVLKQRKDRAFPQILAPIIFSTSISNVNVSIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEVSDTCAQCLSRIFSLMGPQSGKSAVSRESSFGESVSLLWKVDLKVEDMNLFTLSALVGASEIRLDTLTVLGSAETSTVGVQGLVLALVKSVTEKMQPCCKAPDIPTPVLSFSMLSVTYHSSIRSLEVQCGSGLTLLWSPPDHMYLYQHVLATLQCRDLLRTTLFPETVPLVELETAATPSEPEGCPPESSPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFSFKEVEVQLLPELEEMILHRNPFPGLQTLRNRVWLLSLGSVSVEFPYQYDFSRTLDEAVGVQKWLKGLHGGSRSQASPSSAPLPPDILLKVQHFSWVFLDDIFEVKLRDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLEHKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPERVLEQVRELDPGSPFPAEGIDLVIQWCRMLKCSVKTFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILPLGLPWGNVAIERNMPPLKFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWNHLSFHWKPGQFVFKGDLDINVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHGVTLRAPEFLPEVPLGQFHDSYRAFRSENLNLSIKMDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGVQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVTQMVSDLSQATVHLMASPAEENADHCLDPLVTKTHLLSLSSLTYQRHSSRTAEEEPSTRVGDSAFHTHQLHLVDLRASWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPHLPAKKPKQSVPSSAPTPPPVSTPSFSGQPDKGSSGGAYMLKKLIEETDRFVVFTEEESGVSDQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCILDGMQYFATTESSPTEQDGPQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVTTTTDWNQPAEAQQAQQIQRIISRCNCRMYYISYSHDIDPELATQIKPPEVPENQEKEDLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNLKLQLQLNQEKANLQLESEELNILIRCFKDFQLQQANKMELRKQQEDVSVVRRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRIMGFFFPGRSVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDTAPLGPGKGVAQGLNRSSGVRRSFRKAPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKPATGSEVRGKLETKSDLNMQQQEEEEKARLLIGLSVGNKNPGKKSIFGRRK", "length": 2232 }, "evidence": [ { "id": "A0A8V1AME7", "url": "https://omabrowser.org/oma/group/A0A8V1AME7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q14667-1", "protein_name": "Bridge-like lipid transfer protein family member 2", "gene_name": "BLTP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLFFSALLVLLLVALSALFLGRWLVVRLATKWCQRKLQAELKIGSFRFFWIQNVSLKFQQHQQTVEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVSDLSAPFSQSAGVDQKELSFSPSLLKIFCQLFSIHVDAINIMVLKVDTSESLWHIQISRSRFLLDSDGKRLICEVSLCKINSKVLKSGQLEDTCLVELSLALDLCLKVGISSRHLTAITVDVWTLHAELHEGLFQSQLLCQGPSLASKPVPCSEVTENLVEPTLPGLFLLQQLPDQVKVKMENTSVVLSMNSQKRHLTWTLKLLQFLYHRDEDQLPLRSFTANSDMAQMSTELLLEDGLLLSQSRQRIVCLNSLKASVQVTTIDLSASLVLNTCIIHYRHQEFSHWLHLLALETQGSSSPVLKQRKKRTFPQILAPIIFSTSISNVNISIQLGDTPPFALGFNSISLDYQHLRPQSIHQRGVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSDTLFLDCTIRGLQVEASDTCAQCLSRILSLMGPQSGKSAVSRHSSFGESVSLLWKVDLKVEDMNLFTLSALVGASEVRLDTLTILGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLSLSMLSITYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVLATLQCRDLLRATVFPETVPSLALETSGTTSELEGRAPEPLPPKRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFNFKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSFGSVSVEFPYQYDFSRTLDEAVGVQKWLKGLHQGTRAWASPSPVPLPPDLLLKVEHFSWVFLDDVFEVKLHDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPEHVVEQVQELDPGSPFPPEGLDLVIQWCRMLKCNVKSFLVRIRDYPRYLFEIRDWRLMGRLVGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPLKFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFKGDLDINVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIKMDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISDWSVTQMVSDLSQVTVHLMASPTEENADHCLDPLVTKTHLLSLSSLTYQRHSNRTAEEELSARDGDPTFHTHQLHLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMPAKKPKRGVPTSASAPPRVNTPSFSGQPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRQRSLDSVQELMESGQAVGGMVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVLENQEKEDLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRQLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAVYKVVLRPQSSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLTHQFFHRMMGFFFPGRSVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGPGKGVAQGLTRSSGVRRSFRKSPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKSATGSEVRGKLETKSDLNMQQQEEEEKARLLIGLSVGDKNPGKKSIFGRRK", "length": 2235 }, "evidence": [ { "id": "A0A8V1AME7", "url": "https://omabrowser.org/oma/group/A0A8V1AME7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SYL3-1", "protein_name": "Bridge-like lipid transfer protein family member 2", "gene_name": "Bltp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLFLSALLVLLLVALSALFLGRWLVVRLATRWCQRKLQAELKIGSFRFFWIQNVSLKFQQHQQTVEIDNLWISSKLLSHDLPNYVALCFGEVRIRTDLQKVSSLSAPFSQNTEVEQKELSLSPSLLKIFCQLFSIHVDAINIMVLKVATSESLWHIQISRSRFLLDSDGKSLICKVNLSKINSKVLKSGQLEDTCLVELSLALDLRLQVSVSSWHLTAVTVDVWTLHAELHEGLFHSQLLCHAPGRISKSVSCSDLTENFAEPTLPGLYLLQRLPDQVKVKMENTSVVLSMNSQKRHLTWTLKLLHFLYHRDEDQLPLRSFTANYDMAQMSTELLLEDGLLLSQSRQRIVCLNSLKANVQVTTIDLSASLVLNTCIIHYRHQEFSHWLLMLALETQGASSPDLKQRKKRTFPQILAPIIFSTSVSNVSISIQLGDTPPFALGFNSISLDYQHLRPQSIHQRAVLTVDHLCWRVGSDSHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSNTLFLDCTIRGLQVEISDICAQCLSRVLSLVIPQSERSAVSRKSSLGESVTLLWKVDLKVEDMNLFTLSALVGASELRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLGLSMLSLTYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVRATLQCRDLLRATVFPEIIESHSLNTPQSTWEPEDHLPESSLPRRLLTLTLEVSTAKLTAFVAEDKFITLAAESVSLNRHGGSLQAYCPELAAGFDGNSIFNLKEVEVQLLPELEEMILHRNPFPALQTLRNRVWLLSLGSVSVEFPYQYDFSRTLDEAVGVQKWLKGLHRGTHAWASPSPAPLPPDLLLKVQHFSWVFLDDIFEVKLHDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPEHVIEQVRELDPGSPFPAEGMDLVTQWCRMLKCNVKTFLVRIRDYPRYLFEIRDWRLMGRLAGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPLKFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWKPGQFVFRGDLDVNVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIKMDLTRHSGTISQPRILVYSSTLRWMQNFWATWTSITRPICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISEWSVTQMVSDLSQVTVHLMASPTEENADHCLDPLITKTHLLSLSSLTYQRHSNRTTEEELSARDGDPAFHTHQLYLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMSAKKPKRGIPPSAQVPPHVSTPSFSGRPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRERSLDSVQELMESGQAVGGMVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVHENQEKEDLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRHLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAIYKVVLRPQSSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLSHRFFHRMMGFFFPGRNVEDDEVGDEEDKSKLVTTGIPVVKPRQLIATDDAVPLGSGKGVAQGLTRSSGVRRSFRKLPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKPATGSEVRGKLETKCDLNMQQQEEEKARLLIGLSVGDKNPGKKSIFGRRK", "length": 2234 }, "evidence": [ { "id": "A0A8V1AME7", "url": "https://omabrowser.org/oma/group/A0A8V1AME7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1171, "end_pos": 1173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1268, "end_pos": 1270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1440, "end_pos": 1442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1494, "end_pos": 1496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1860, "end_pos": 1862, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1955, "end_pos": 1957, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2092, "end_pos": 2094, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2122, "end_pos": 2124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2162, "end_pos": 2164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2207, "end_pos": 2209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AME7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME7" }, { "id": "SM01214", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit", "eco_id": "ECO_0000259", "start_pos": 1040, "end_pos": 1172, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1171, "end_pos": 1173 }, { "start_pos": 1268, "end_pos": 1270 }, { "start_pos": 1440, "end_pos": 1442 }, { "start_pos": 1494, "end_pos": 1496 }, { "start_pos": 1860, "end_pos": 1862 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 1955, "end_pos": 1957 }, { "start_pos": 2092, "end_pos": 2094 }, { "start_pos": 2122, "end_pos": 2124 }, { "start_pos": 2162, "end_pos": 2164 }, { "start_pos": 2207, "end_pos": 2209 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 654, "end_pos": 656 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AME9-1", "uniprot_ac": "A0A8V1AME9", "uniprot_id": "A0A8V1AME9_CHICK", "mass": { "chemical_mass": 34366.0, "monoisotopic_mass": 34366.0 }, "refseq": { "ac": "XP_040543439", "name": "fibrinogen-like protein 1-like protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543439" }, "gene_names": [ { "name": "LOC112530086", "type": "recommended", "evidence": [ { "id": "A0A8V1AME9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9" } ] }, { "name": "LOC112530086", "type": "synonym", "evidence": [ { "id": "XP_040543439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543439" } ] } ], "protein_names": [ { "name": "Fibrinogen C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AME9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9/entry#names_and_taxonomy" } ] }, { "name": "fibrinogen-like protein 1-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040543439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543439" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052591.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040543439.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040543439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543439" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112530086", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9", "locus": {} } ], "crossref": [ { "id": "A0A8V1AME9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AME9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112530086", "url": "https://www.ncbi.nlm.nih.gov/gene/112530086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AME9", "url": "https://www.orthodb.org/?gene=A0A8V1AME9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF438", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF438", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040543439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543439", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AME9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AME9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSAGQKGTRFDSHPQEKGGCVGQTRSPHPLQRALQVPLPLRPHSSARQREPCAAAMVTQCLPLLASVLVLAAPGLSVPAQAQNTSKKTFSSTWTNTLKKDSWPKDCSEISAGSPSGVYVIQPSGLHPIVVYCEMNVTGGGWTVIQRNRYNTDITWAESWSTYKYGFGNVHSDYWLGTEYIHQIAKQKVYRVRFVIQDASNNIRFAEYNLFSVDNESQGYRLRLGSYSGTAGDAMDSDNPSNMHNNMKFSTKDRDQDTSRKNCASRSGGGWWYSACYSVRLNFKGGMTWGSLCQGDCNSSLILIRPAPYT", "length": 310, "header": "tr|A0A8V1AME9-1|A0A8V1AME9_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112530086 PE=4 SV=1 CANONICAL=A0A8V1AME9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AME9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9/entry#A0A8V1AME9-1", "sequence": { "sequence": "MFSAGQKGTRFDSHPQEKGGCVGQTRSPHPLQRALQVPLPLRPHSSARQREPCAAAMVTQCLPLLASVLVLAAPGLSVPAQAQNTSKKTFSSTWTNTLKKDSWPKDCSEISAGSPSGVYVIQPSGLHPIVVYCEMNVTGGGWTVIQRNRYNTDITWAESWSTYKYGFGNVHSDYWLGTEYIHQIAKQKVYRVRFVIQDASNNIRFAEYNLFSVDNESQGYRLRLGSYSGTAGDAMDSDNPSNMHNNMKFSTKDRDQDTSRKNCASRSGGGWWYSACYSVRLNFKGGMTWGSLCQGDCNSSLILIRPAPYT", "length": 310, "header": "tr|A0A8V1AME9-1|A0A8V1AME9_CHICK Isoform 1 of Fibrinogen C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112530086 PE=4 SV=1 CANONICAL=A0A8V1AME9-1" }, "locus": { "chromosome": "19", "start_pos": 581542, "end_pos": 580056, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071316.1", "url": "https://www.ensembl.org/id/ENSGALT00010071316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044007.1", "url": "https://www.ensembl.org/id/ENSGALP00010044007.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AME9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AME9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AME9" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 282, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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GN=CCDC137 PE=4 SV=1 CANONICAL=A0A8V1AMG0-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG0/entry#A0A8V1AMG0-1", "sequence": { "sequence": "RSHSVPRGLRHRRTSLCPGSVGAEGNQSAPTRAAWNGRCSICWSSARTRCSGSLRRRQQHRRSLRERKSESKASTAAEAVLGQPGPCPDSETPLYRAGSESIPWSSCTLLVPGQAGESSRAWLPRGFHGVEALFLPAGCKIALQVSEQKAGQSAEEEGGEERSFAGEEAVPRWGIAQGGWLQRPMRRGGSSILPDTRFFSLPDPVAFGEVVTEPPTITSRPRSGGPTEKVRCGGTELCACLCISDPPHLCPQAGRKRLLLTPRLGQSRAAPTVPVSMARQRIVQEERARVIQAYRDIQRRKQQQRDAARGSTQPSSRVPG", "length": 320, "header": "tr|A0A8V1AMG0-1|A0A8V1AMG0_CHICK Isoform 1 of Coiled-coil domain containing 137 OS=Gallus gallus OX=9031 GN=CCDC137 PE=4 SV=1 CANONICAL=A0A8V1AMG0-1" }, "locus": { "chromosome": "18", "start_pos": 9774019, "end_pos": 9773060, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071331.1", "url": "https://www.ensembl.org/id/ENSGALT00010071331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044022.1", "url": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMG9-1", "uniprot_ac": "A0A8V1AMG9", "uniprot_id": "A0A8V1AMG9_CHICK", "mass": { "chemical_mass": 34228.0, "monoisotopic_mass": 34228.0 }, "refseq": { "ac": "XP_040505896", "name": "germ cell-specific gene 1-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505896" }, "gene_names": [ { "name": "GSG1L2", "type": "recommended", "evidence": [ { "id": "A0A8V1AMG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG9" } ] }, { "name": "GSG1L2", "type": "synonym", "evidence": [ { "id": "XP_040505896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505896" } ] } ], "protein_names": [ { "name": "Germ cell-specific gene 1-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AMG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG9/entry#names_and_taxonomy" } ] }, { "name": "germ cell-specific gene 1-like protein 2", "type": "synonym", "evidence": [ { "id": "XP_040505896", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505896" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505896", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505896" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GSG1L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG9", "locus": { "chromosome": "18", "start_pos": 753077, "end_pos": 769391, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029191", "url": "https://www.ensembl.org/id/ENSGALG00010029191" } ] } } ], "crossref": [ { "id": "A0A8V1AMG9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "768455", "url": "https://www.ncbi.nlm.nih.gov/gene/768455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MTGEKCR", "url": "https://omabrowser.org/oma/group/MTGEKCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMG9", "url": "https://www.orthodb.org/?gene=A0A8V1AMG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671:SF40", "url": 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"MIVSEQIQQSQRMPVSVPGTDRRQRASVAFFLSFLSLVFSITAFSSNYWCEGTRKVAKPFCVGQAKGDHCIRFNSPDANNSNAVQYIWETGDDKFVDRKFHAGIWYSCEEVINGEGEKCRSFISLTPASDRGVLWLSIVAELLYNILLLTGVVLMLVEMCYYSTVIDGLKINAFSAVVIVLAGLLGMVAHMMYTTVFQMTVNLGPEDWRPHAWDYGWSYCLAWASFACCMAAAVTTINKYTKTILEFKHKRKMLERSLKIKCKFPDHAAPQKACSVYVNSFHNTTEDCAHPVKDLHHLGTISVL", "length": 304, "header": "tr|A0A8V1AMG9-1|A0A8V1AMG9_CHICK Isoform 1 of Germ cell-specific gene 1-like protein OS=Gallus gallus OX=9031 GN=GSG1L2 PE=3 SV=1 CANONICAL=A0A8V1AMG9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG9/entry#A0A8V1AMG9-1", "sequence": { "sequence": "MIVSEQIQQSQRMPVSVPGTDRRQRASVAFFLSFLSLVFSITAFSSNYWCEGTRKVAKPFCVGQAKGDHCIRFNSPDANNSNAVQYIWETGDDKFVDRKFHAGIWYSCEEVINGEGEKCRSFISLTPASDRGVLWLSIVAELLYNILLLTGVVLMLVEMCYYSTVIDGLKINAFSAVVIVLAGLLGMVAHMMYTTVFQMTVNLGPEDWRPHAWDYGWSYCLAWASFACCMAAAVTTINKYTKTILEFKHKRKMLERSLKIKCKFPDHAAPQKACSVYVNSFHNTTEDCAHPVKDLHHLGTISVL", "length": 304, "header": "tr|A0A8V1AMG9-1|A0A8V1AMG9_CHICK Isoform 1 of Germ cell-specific gene 1-like protein OS=Gallus gallus OX=9031 GN=GSG1L2 PE=3 SV=1 CANONICAL=A0A8V1AMG9-1" }, "locus": { "chromosome": "18", "start_pos": 769192, "end_pos": 754081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070545.1", "url": "https://www.ensembl.org/id/ENSGALT00010070545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043236.1", "url": "https://www.ensembl.org/id/ENSGALP00010043236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMG9" } ], "pmid": "" }, { "name": "plasma 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] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMH4-1", "uniprot_ac": "A0A8V1AMH4", "uniprot_id": "A0A8V1AMH4_CHICK", "mass": { "chemical_mass": 35423.0, "monoisotopic_mass": 35423.0 }, "refseq": {}, "gene_names": [ { "name": "LOC112530081", "type": "recommended", "evidence": [ { "id": "A0A8V1AMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4" } ] } ], "protein_names": [ { "name": "PHD-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1AMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC112530081", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4", "locus": {} } ], "crossref": [ { "id": "A0A8V1AMH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15669", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15669", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMH4", "url": "https://www.orthodb.org/?gene=A0A8V1AMH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12420", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12420:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12420:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26054", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26054", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AMH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLFSLQRGHQEGGDMSRPGAVLSAGAAGALPERVSQRSKPNYDPDIYGETCRQDRLCVHENCLYHASGLYQHGADDEGFFGFLLPDIEQTLQRVAEKVCCVCRRRGASVRCHRRRCSRTFHYPCGRERGCVSQFFGEYRSFCWQHRPTQQVQPLRQQHPQCAICLEAVQGRPCYRTLICPSCTSAHFHRHCIQGQALRAALHHFRCPLCQDMQTFQAEMFRLGIKIPDRDAAWEEEGAFNELSQRHNSCDASLCLCSLGRDYSNNTGPWRMLLCSSCASCGTHQRCSAIPEDAESWECSGCSGVGTGKKCSTGSP", "length": 316, "header": "tr|A0A8V1AMH4-1|A0A8V1AMH4_CHICK Isoform 1 of PHD-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112530081 PE=4 SV=1 CANONICAL=A0A8V1AMH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4/entry#A0A8V1AMH4-1", "sequence": { "sequence": "MVLFSLQRGHQEGGDMSRPGAVLSAGAAGALPERVSQRSKPNYDPDIYGETCRQDRLCVHENCLYHASGLYQHGADDEGFFGFLLPDIEQTLQRVAEKVCCVCRRRGASVRCHRRRCSRTFHYPCGRERGCVSQFFGEYRSFCWQHRPTQQVQPLRQQHPQCAICLEAVQGRPCYRTLICPSCTSAHFHRHCIQGQALRAALHHFRCPLCQDMQTFQAEMFRLGIKIPDRDAAWEEEGAFNELSQRHNSCDASLCLCSLGRDYSNNTGPWRMLLCSSCASCGTHQRCSAIPEDAESWECSGCSGVGTGKKCSTGSP", "length": 316, "header": "tr|A0A8V1AMH4-1|A0A8V1AMH4_CHICK Isoform 1 of PHD-type domain-containing protein OS=Gallus gallus OX=9031 GN=LOC112530081 PE=4 SV=1 CANONICAL=A0A8V1AMH4-1" }, "locus": { "chromosome": "19", "start_pos": 4699350, "end_pos": 4696654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070550.1", "url": "https://www.ensembl.org/id/ENSGALT00010070550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043241.1", "url": "https://www.ensembl.org/id/ENSGALP00010043241.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4" } ], "pmid": "" } ] }, { "name": "Molecular 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"url": "https://prosite.expasy.org/PS51805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 147, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMH4" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 211, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AP17-1", "uniprot_ac": "A0A8V1AP17", "uniprot_id": "A0A8V1AP17_CHICK", "mass": { "chemical_mass": 95467.0, "monoisotopic_mass": 95467.0 }, "refseq": { "ac": "XP_015151350", "name": "A-kinase anchor protein 1, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151350" }, "gene_names": [ { "name": "AKAP1", "type": "recommended", "evidence": [ { "id": "A0A8V1AP17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ] }, { "name": "AKAP1", "type": "synonym", "evidence": [ { "id": "XP_015151350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151350" } ] } ], "protein_names": [ { "name": "A-kinase anchor protein 1, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_015151350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151350" } ] }, { "name": "A-kinase anchoring protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V1AP17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151350.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151350" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AKAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17", "locus": { "chromosome": "19", "start_pos": 9458502, "end_pos": 9481902, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029522", "url": "https://www.ensembl.org/id/ENSGALG00010029522" } ] } } ], "crossref": [ { "id": "A0A8V1AP17", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP17", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22395", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22395", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417668", "url": "https://www.ncbi.nlm.nih.gov/gene/417668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047368", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047368", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417668", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417668", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLTNIYT", "url": "https://omabrowser.org/oma/group/CLTNIYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMI1", "url": "https://www.orthodb.org/?gene=A0A8V1AMI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP17", "url": "https://www.orthodb.org/?gene=A0A8V1AP17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22948:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRFRTFFPYAIPGVLALLGCWWIYSHRKKHPSNRNRQAIAIAEGKQKELPENDSPPKTEACVPQRLPLSPEEERPENETSASLLPAGPMTPSPTRRTRERLDFSRDLSAPAIRTTQPSTVEDDSEKLEIKGSQDESSVPACVSLPLISKSTKCRSGAAVSPEEDSGSSTNQAKCPSASVVPTQRSLGITEEISNAEQSDESSLKPPKESQMPEIALSDTGCMTALHLGLEKEADAPQALLTNEVVLSHQDSAVRVLSGSLESACLEQSREEKIPESNDSTVPVCQGEDTHAKGNELERERIRGVSLDKEEVEKIEQVAIQIISKVILAATEEVLAGSVSDVSSRICQAAASRVERPQERASTASSDQLLAAEAGGGDKNTALKSDAAVPTSLPTEERDQCVTYSSCSALGHLSSPVQGDTQDHQEKNCVHSESQGVDRTLVASHGGSLGKSHLVMEDSGCSTCASEGGTSVEDPLQNTLLSVASGQHSDLLSTSATQDTSAEQSSEPSEKPPTLKLPEDSKVPYSNGMLKEDGSDSRHEGNWAAEMDGDHSGGSDVNSMDSVDSGCALGKTETHQNSKPGGESSKSDLTIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYSHDFQICHIEGSQHHVEKALSLIGKKFKELSLTNIYAPPPPSLTLHSLPMTSWLMLPDGVTVEVVVANQVNAGHMFLQQHTHPTFHVLRSLDQQMYVCYSQPGIPTLPTPVEVGIICAAPGLEGAWWRAQVVGYFKDSGEVEIRYVDYGGYERVKIDTLRQIRSDFVTLPFQGAEVLLDNVVPLPDEDHFSSEADAAVSEMTRGAALLAQVTNYDNATGLPLIQLWSMMGDEVVSINRTLVERGFAQWVDNY", "length": 883, "header": "tr|A0A8V1AP17-1|A0A8V1AP17_CHICK Isoform 1 of A-kinase anchoring protein 1 OS=Gallus gallus OX=9031 GN=AKAP1 PE=1 SV=1 CANONICAL=A0A8V1AP17-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17/entry#A0A8V1AMI1-1", "sequence": { "sequence": "MALRFRTFFPYAIPGVLALLGCWWIYSHRKKHPSNRNRQAIAIAEGKQKELPENDSPPKTEACVPQRLPLSPEEERPENETSASLLPAGPMTPSPTRRTRERLDFSRDLSAPAIRTTQPSTVEDDSEKLEIKGSQDESSVPACVSLPLISKSTKCRSGAAVSPEEDSGSSTNQAKCPSASVVPTQRSLGITEEISNAEQSDESSLKPPKESQMPEIALSDTGCMTALHLGLEKEADAPQALLTNEVVLSHQDSAVRVLSGSLESACLEQSREEKIPESNDSTVPVCQGEDTHAKGNELERERIRGVSLDKEEVEKIEQVAIQIISKVILAATEEVLAGSVSDVSSRICQAAASRVERPQERASTASSDQLLAAEAGGGDKNTALKSDAAVPTSLPTEERDQCVTYSSCSALGHLSSPVQGDTQDHQEKNCVHSESQGVDRTLVASHGGSLGKSHLVMEDSGCSTCASEGGTSVEDPLQNTLLSVASGQHSDLLSTSATQDTSAEQSSEPSEKPPTLKLPEDSKVPYSNGMLKEDGSDSRHEGNWAAEMDGDHSGGSDVNSMDSVDSGCALGKTETHQNSKPGGESSKSDLTIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYSHDFQICHIEGSQHHVEKALSLIGKKFKELSLTNIYAPPPPSLTLHSLPMTSWLMLPDGVTVEVVVANQVNAGHMFLQQHTHPTFHVLRSLDQQMYVCYSQPGIPTLPTPVEVGIICAAPGLEGAWWRAQVVGYFKDSGEVEIRYVDYGGYERVKIDTLRQIRSDFVTLPFQGAEVLLDNVVPLPDEDHFSSEADAAVSEMTRGAALLAQVTNYDNATGLPLIQLWSMMGDEVVCASL", "length": 869, "header": "tr|A0A8V1AMI1-1|A0A8V1AP17_CHICK Computationally mapped isoform of A-kinase anchoring protein 1 OS=Gallus gallus OX=9031 GN=AKAP1 PE=1 SV=1 CANONICAL=A0A8V1AP17-1" }, "locus": { "chromosome": "19", "start_pos": 9470135, "end_pos": 9459506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071361.1", "url": "https://www.ensembl.org/id/ENSGALT00010071361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044052.1", "url": "https://www.ensembl.org/id/ENSGALP00010044052.1" } ] } }, { "isoform_ac": "A0A8V1AP17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17/entry#A0A8V1AP17-1", "sequence": { "sequence": "MALRFRTFFPYAIPGVLALLGCWWIYSHRKKHPSNRNRQAIAIAEGKQKELPENDSPPKTEACVPQRLPLSPEEERPENETSASLLPAGPMTPSPTRRTRERLDFSRDLSAPAIRTTQPSTVEDDSEKLEIKGSQDESSVPACVSLPLISKSTKCRSGAAVSPEEDSGSSTNQAKCPSASVVPTQRSLGITEEISNAEQSDESSLKPPKESQMPEIALSDTGCMTALHLGLEKEADAPQALLTNEVVLSHQDSAVRVLSGSLESACLEQSREEKIPESNDSTVPVCQGEDTHAKGNELERERIRGVSLDKEEVEKIEQVAIQIISKVILAATEEVLAGSVSDVSSRICQAAASRVERPQERASTASSDQLLAAEAGGGDKNTALKSDAAVPTSLPTEERDQCVTYSSCSALGHLSSPVQGDTQDHQEKNCVHSESQGVDRTLVASHGGSLGKSHLVMEDSGCSTCASEGGTSVEDPLQNTLLSVASGQHSDLLSTSATQDTSAEQSSEPSEKPPTLKLPEDSKVPYSNGMLKEDGSDSRHEGNWAAEMDGDHSGGSDVNSMDSVDSGCALGKTETHQNSKPGGESSKSDLTIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYSHDFQICHIEGSQHHVEKALSLIGKKFKELSLTNIYAPPPPSLTLHSLPMTSWLMLPDGVTVEVVVANQVNAGHMFLQQHTHPTFHVLRSLDQQMYVCYSQPGIPTLPTPVEVGIICAAPGLEGAWWRAQVVGYFKDSGEVEIRYVDYGGYERVKIDTLRQIRSDFVTLPFQGAEVLLDNVVPLPDEDHFSSEADAAVSEMTRGAALLAQVTNYDNATGLPLIQLWSMMGDEVVSINRTLVERGFAQWVDNY", "length": 883, "header": "tr|A0A8V1AP17-1|A0A8V1AP17_CHICK Isoform 1 of A-kinase anchoring protein 1 OS=Gallus gallus OX=9031 GN=AKAP1 PE=1 SV=1 CANONICAL=A0A8V1AP17-1" }, "locus": { "chromosome": "19", "start_pos": 9470135, "end_pos": 9460268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071359.1", "url": "https://www.ensembl.org/id/ENSGALT00010071359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044050.1", "url": "https://www.ensembl.org/id/ENSGALP00010044050.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417668", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417668", "resource": "KEGG Pathway" }, { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BMU6-1", "protein_name": "A-kinase anchoring protein 1", "gene_name": "AKAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTIQFRSLFPLALPGVLALLGWWWFFSRKKEPLDSHDRAAEAGAVALRAGPEAQEVLPVEDSRPGAASPPPERELCGGGRPSPEPAALLRAHPACRRSESSGSLPNPADTRLRPGARKEVELTLAGDEAKAVPLECPLPAPKGLPFPHEAVEVCKREAVLGRPGGRGRQGQPAAPAEKPAPEEKARETGGAEGTGDAVLGENVLEEGPAAWEPAPELELQSSRAAGAGEKDPGRLLEEAVVEAAPEEETLAPRGLAGRAWDGAFPQEQGGEETWDRSEKIEQAAFQIISKVILEATEEVLATTMGRIAGRVYQASATQPQGLKEESCAPASQKTPLGLEASEPTLTAVEAAPGLRDTALPSTEPPAGDLPAPKTYVSCLSSPLSSPTKDRKPKNSAHHISLAPCPLPAAPLRELLDEAGGTGEETTHVPCVSDGGQAVPCGAASGQCSDSASTSGLEDCCLETSPSPRGEAATPPLPESTVPVSNGVLKGELSDLGTEDGWTVDAEADHSGGSDGNSMDSVDSCCGFRKPDDFQNAQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQVCHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGVTVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGVDGAWWRAQVVAAYEDTNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVMPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYSSL", "length": 843 }, "evidence": [ { "id": "A0A8V1AP17", "url": "https://omabrowser.org/oma/group/A0A8V1AP17/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08715-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "Akap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIQLRSLFPLALPGMLALLGWWWFFSRKKDRLSSSDKQVETLKVGPAIKDRRLSEEACPGVLSVAPTVTQPPGREEQRCVDKPSTEPLALPRTRQVRRRSESSGNLPSVADTRSQPGPCRDEIAKVELSLMGDKAKSIPLGCPLLPKDASFPYEAVERCKQESALGKTPGRGWPSPYAASGEKARETGGTEGTGDAVLGENVSEEGLLSQECVSEVEKSEFPILAPGGGEGEEVSHGPPQVAELLKKEEYIVGKLPSSFVEPVHSEPVKDEDALEPQVKGSSNTSDRDLAGELDKDETVPENDQIKQAAFQLISQVILEATEEFRATTVGKTVAQVHPTSATQPKGKEESCVPASQETSLGQDTSDPASTRTGATASPSAEALPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLEGASNPRGDDNFVACMANNSQSVLSVSSLGQCSDPVSTSGLEDSCTETISSSGDKAMTPPLPVSTQPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQSVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYASL", "length": 857 }, "evidence": [ { "id": "A0A8V1AP17", "url": "https://omabrowser.org/oma/group/A0A8V1AP17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88884-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "Akap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKDRLSSNGKQVGTLKVGPAIEDRLPTEEACPGVLSVTPSVTQPPGKEEQRSMDRPLSDPPALPRTRQVRRRSESSGNLPSIVDTRLQAGQCSDENSKVVLSLMGDEAKSIPLGRPLFPKDLSFPYEAVEGCKQESALGRTPGRGWLSQCAASGENARETGGAEGTGDAVLGESVLEEGLLPQECVSEVEKSEFPILAPGGGGGEKVRSGPPQVDELLKKEEYIVGKLPSSFVGPVHSELVKDEGALVPQVKGSQDRSLARELDKDKTLPEKDQIEQTAFQIISQVILEATEEIRATTVGKTVAQVHPTPGTQPQGQEESCVPASQETSLGQEIPDPASTRTGATASPSAGAPPPKTYVSCLSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLDGASNPRGDDTFVTCTSNNSQSVLSVTSLGLCSDPVSTSRLEDSCTETISSSGDKAVTPPLPDSTEPFSNGVLKEELSDLGTEDGWTMDTEADHSGGSDGNSMDSVDSCCGLTKPDSPQTVQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSCYASL", "length": 854 }, "evidence": [ { "id": "A0A8V1AP17", "url": "https://omabrowser.org/oma/group/A0A8V1AP17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92667-1", "protein_name": "A-kinase anchor protein 1, mitochondrial", "gene_name": "AKAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPAEPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQPGYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSRFIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEATEQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDSKPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPESTVPFSNGVLKGELSDLGAEDGWTMDAEADHSGGSDRNSMDSVDSCCSLKKTESFQNAQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQSVQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYTSL", "length": 903 }, "evidence": [ { "id": "A0A8V1AP17", "url": "https://omabrowser.org/oma/group/A0A8V1AP17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ], "pmid": "" }, { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WDINVRY", "url": "https://omabrowser.org/oma/group/WDINVRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMI7", "url": "https://www.orthodb.org/?gene=A0A8V1AMI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44321:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44321:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAALGAGLGLLLALLLLAAALRRAAPRGSPAAPPRGEGAGANGHAAARPEGPRRAKPPARARKDKPQQHSFAHRLLAAALKGHSGSVSCLHFSGSGKYLASCADDRTVRLWSTRDFTAREHRCLRANVELDHAELVRFSPDCRAFIVWLANGETIRVYKMTKKDDGNFTFTASSEDFPKKHKAPVINIGVAETGKFIMTASSDTTILIWNLKGEVLASINTNQMNNAYAAVSPCGRFVASCGFTPDVKVWEVCFGKSGDFREVTRAFELKGHTAGIYSFSFSNDSRRMATVSKDGTWKFWDTDVEYKKQQDPYLLLTGRCEVAEPCRIALSPDAHVVAISCGTTIVVFNTRRGEEEERFVGVHGQHIADLAFDTTSRYLVSCGDRAIRVFHNTPGYRAVVEEMETMLRKTTTKATRERLEQQITSAKKALAAICGRKQ", "length": 440, "header": "tr|A0A8V1AMI7-1|A0A8V1AMI7_CHICK Isoform 1 of Transducin beta like 2 OS=Gallus gallus OX=9031 GN=TBL2 PE=1 SV=1 CANONICAL=A0A8V1AMI7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7/entry#A0A8V1AMI7-1", "sequence": { "sequence": "MEAAALGAGLGLLLALLLLAAALRRAAPRGSPAAPPRGEGAGANGHAAARPEGPRRAKPPARARKDKPQQHSFAHRLLAAALKGHSGSVSCLHFSGSGKYLASCADDRTVRLWSTRDFTAREHRCLRANVELDHAELVRFSPDCRAFIVWLANGETIRVYKMTKKDDGNFTFTASSEDFPKKHKAPVINIGVAETGKFIMTASSDTTILIWNLKGEVLASINTNQMNNAYAAVSPCGRFVASCGFTPDVKVWEVCFGKSGDFREVTRAFELKGHTAGIYSFSFSNDSRRMATVSKDGTWKFWDTDVEYKKQQDPYLLLTGRCEVAEPCRIALSPDAHVVAISCGTTIVVFNTRRGEEEERFVGVHGQHIADLAFDTTSRYLVSCGDRAIRVFHNTPGYRAVVEEMETMLRKTTTKATRERLEQQITSAKKALAAICGRKQ", "length": 440, "header": "tr|A0A8V1AMI7-1|A0A8V1AMI7_CHICK Isoform 1 of Transducin beta like 2 OS=Gallus gallus OX=9031 GN=TBL2 PE=1 SV=1 CANONICAL=A0A8V1AMI7-1" }, "locus": { "chromosome": "19", "start_pos": 701975, "end_pos": 697741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071373.1", "url": "https://www.ensembl.org/id/ENSGALT00010071373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044063.1", "url": "https://www.ensembl.org/id/ENSGALP00010044063.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FBV4-1", "protein_name": "Transducin beta like 2", "gene_name": "TBL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELPQMPELMGLSLLLGLLALMATAAVARGWLRAEEETGRPVGQKANGLPPDKSLKSKKQKQRIRKEKPQQHNFTHRLLAAALKSHNGNISCMDFSSNGKYLATCADDRTIRIWSTKDFLQREHRSMRANVELDHAILVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKASIVNIGIADTGKFIMTASSDTTILIWNLKGQVLSTINTNQMNNTYAAISPCSRFVASCGFTPDVKVWEVCFGKKGDFQEVVRAFELKGHSAAVHFFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQDPYLLRTGRFQEASTMPCRLALSPDSQVLALACGTSIHLYSTRRGEEEERFEQVHGECITDLSFDITGRFLASCGDRAVRLFHNAPGHRAVVEEMTLGVQHCCRHCCLFSRYTPAGNRSKGVS", "length": 436 }, "evidence": [ { "id": "A0A8V1AMI7", "url": "https://omabrowser.org/oma/group/A0A8V1AMI7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RCS2-1", "protein_name": "Transducin beta-like protein 2", "gene_name": "Tbl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELPQMPELMGLSLLVGLLALVATAAVARGWLRAEEKPSQPICQKENESKKSVSKKQKQNQRIRKEKPQQHNFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTMPCRLALSPDTHVLALATGTSIHLFNTRRGEKEEYFECVHGECIADLTFDITGRFLASCGDRAVRLFHNTPGHRAVVEEMQGLLKRASSESTRQRLQQQLTQAQEALKSLGALKK", "length": 442 }, "evidence": [ { "id": "A0A8V1AMI7", "url": "https://omabrowser.org/oma/group/A0A8V1AMI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R099-1", "protein_name": "Transducin beta-like protein 2", "gene_name": "Tbl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELPQMPELMGLSLLVGLLALVATAAVARGWLRAEEKPSQPVCQKENEPKKSGSKKQKQNQRVRKEKPQQHSFTHPLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGFTFTATPEDFPKKHKAPIINIGIADTGKFIMTASSDTTVLIWNLKGQVLSTINTNQMNNSHAVISPCSRFVGSCGFTPDVKVWEVCFGKKGEFQEVLRAFELKGHSASVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKQQDPYLLRTGRFEEASTMPCRLALSPDTHVLALATGTNIHLFNTRRGEKEEYFECVHGECIADLTFDITGRFLASCGDRAVRLFHNTPGHRAVVEEMQSLLKRASSESTRQRLQQQLTQAQEALKSLGALKK", "length": 442 }, "evidence": [ { "id": "A0A8V1AMI7", "url": "https://omabrowser.org/oma/group/A0A8V1AMI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y4P3-1", "protein_name": "Transducin beta-like protein 2", "gene_name": "TBL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSQMSELMGLSVLLGLLALMATAAVARGWLRAGEERSGRPACQKANGFPPDKSSGSKKQKQYQRIRKEKPQQHNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKDFLQREHRSMRANVELDHATLVRFSPDCRAFIVWLANGDTLRVFKMTKREDGGYTFTATPEDFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSLKGQVLSTINTNQMNNTHAAVSPCGRFVASCGFTPDVKVWEVCFGKKGEFQEVVRAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTDVEYKKKQDPYLLKTGRFEEAAGAAPCRLALSPNAQVLALASGSSIHLYNTRRGEKEECFERVHGECIANLSFDITGRFLASCGDRAVRLFHNTPGHRAMVEEMQGHLKRASNESTRQRLQQQLTQAQETLKSLGALKK", "length": 447 }, "evidence": [ { "id": "A0A8V1AMI7", "url": "https://omabrowser.org/oma/group/A0A8V1AMI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" }, { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 285, "end_pos": 287 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AMI9-1", "uniprot_ac": "A0A8V1AMI9", "uniprot_id": "A0A8V1AMI9_CHICK", "mass": { "chemical_mass": 57494.0, "monoisotopic_mass": 57494.0 }, "refseq": {}, "gene_names": [ { "name": "RABGEF1", "type": "recommended", "evidence": [ { "id": "A0A8V1AMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ] } ], "protein_names": [ { "name": "Rab5 GDP/GTP exchange factor", "type": "recommended", "evidence": [ { "id": "A0A8V1AMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9/entry#names_and_taxonomy" } ] }, { "name": "Rabex-5", "type": "synonym", "evidence": [ { "id": "A0A8V1AMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a guanine-nucleotide releasing factor (GEF) for RAB5A by promoting the conversion of inactive RAB-GDP to the active form RAB-GTP. Forms a complex with RABEP1 that acts as Rab4/Rab5 effector regulating endosome fusion. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Also functions as a ubiquitin ligase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9#function" }, { "database": "UniProtKB", "id": "ARBA00094214", "url": "https://www.uniprot.org/uniprotkb/ARBA00094214#function" }, { "database": "UniProtKB", "id": "A0A8V1AP21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP21#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RABGEF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9", "locus": { "chromosome": "19", "start_pos": 5540805, "end_pos": 5527175, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029966", "url": "https://www.ensembl.org/id/ENSGALG00010029966" } ] } } ], "crossref": [ { "id": "A0A8V1AMI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "417548", "url": "https://www.ncbi.nlm.nih.gov/gene/417548", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTITCAT", "url": "https://omabrowser.org/oma/group/PTITCAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMI9", "url": "https://www.orthodb.org/?gene=A0A8V1AMI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP21", "url": "https://www.orthodb.org/?gene=A0A8V1AP21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23101:SF126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23101:SF126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP21", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTKKMSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAYASSQSTQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFTASSRTGAKKAEIQEAKAPSPSINRQASIETDRVSKEFIEFLKTYHKPGQDIYKQCKLFLDTMNHKRDLSIEEQSECAQDFYQNVAEKLQTRWKVPPEKVEKAMDQIEKYIMTRQYKYVFCPETTDDEKKDLTVQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRFMTGQTSPKKQESDSWSPDVCLGVKQMYKNLDLLSQLNERQDRIVSEAKKLEKDLIDWTDGVAKEVQDIVEKYPLEIKPKNQALAAIDSENVENDKLPPPLQPQVYAG", "length": 497, "header": "tr|A0A8V1AMI9-1|A0A8V1AMI9_CHICK Isoform 1 of Rab5 GDP/GTP exchange factor OS=Gallus gallus OX=9031 GN=RABGEF1 PE=1 SV=1 CANONICAL=A0A8V1AMI9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9/entry#A0A8V1AMI9-1", "sequence": { "sequence": "MQTKKMSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAYASSQSTQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFTASSRTGAKKAEIQEAKAPSPSINRQASIETDRVSKEFIEFLKTYHKPGQDIYKQCKLFLDTMNHKRDLSIEEQSECAQDFYQNVAEKLQTRWKVPPEKVEKAMDQIEKYIMTRQYKYVFCPETTDDEKKDLTVQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRFMTGQTSPKKQESDSWSPDVCLGVKQMYKNLDLLSQLNERQDRIVSEAKKLEKDLIDWTDGVAKEVQDIVEKYPLEIKPKNQALAAIDSENVENDKLPPPLQPQVYAG", "length": 497, "header": "tr|A0A8V1AMI9-1|A0A8V1AMI9_CHICK Isoform 1 of Rab5 GDP/GTP exchange factor OS=Gallus gallus OX=9031 GN=RABGEF1 PE=1 SV=1 CANONICAL=A0A8V1AMI9-1" }, "locus": { "chromosome": "19", "start_pos": 5538122, "end_pos": 5527255, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072405.1", "url": "https://www.ensembl.org/id/ENSGALT00010072405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044852.1", "url": "https://www.ensembl.org/id/ENSGALP00010044852.1" } ] } }, { "isoform_ac": "A0A8V1AP21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9/entry#A0A8V1AP21-1", "sequence": { "sequence": "MSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAYASSQSTQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFTASSRTGAKKVAQEKVVKQGQLGRERNADNILRDLKEIFTPSWELASPTEAEIQEAKAPSPSINRQASIETDRVSKEFIEFLKTYHKPGQDIYKQCKLFLDTMNHKRDLSIEEQSECAQDFYQNVAEKLQTRWKVPPEKVEKAMDQIEKYIMTRQYKYVFCPETTDDEKKDLTVQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRFMTGQTSPKKQESDSWSPDVCLGVKQMYKNLDLLSQLNERQDRIVSEAKKLEKDLIDWTDGVAKEVQDIVEKYPLEIKPKNQALAAIDSENVENDKLPPPLQPQVYAG", "length": 532, "header": "tr|A0A8V1AP21-1|A0A8V1AP21_CHICK Computationally mapped isoform of Rab5 GDP/GTP exchange factor OS=Gallus gallus OX=9031 GN=RABGEF1 PE=1 SV=1 CANONICAL=A0A8V1AMI9-1" }, "locus": { "chromosome": "19", "start_pos": 5538122, "end_pos": 5527473, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072403.1", "url": "https://www.ensembl.org/id/ENSGALT00010072403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044851.1", "url": "https://www.ensembl.org/id/ENSGALP00010044851.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ABA8-1", "protein_name": "Rab5 GDP/GTP exchange factor", "gene_name": "Rabgef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGGDAHPLSQNTGREPAWSIEKKMSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQRQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRAGSKKEIQEAKAPSPSINRQTSIETDRVTKEFIDFLKTFHKTGQEVYKQTKMFLEAMPYKRDLSIEEQSECTQDFYQNVAERLQTRGKVPPEKVEKMMDQIEKHIMTRLYKFVFCPETTDDEKKDLAIQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITRCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQESESWSPEACLGVKQMYKNLDLLSQLNERQERIMTEAKKLEKDLIDWTDGIAKEVQDIVEKYPLEIKPPNQPLAAIDSENVENDKLPPPLQPQVYAG", "length": 515 }, "evidence": [ { "id": "A0A8V1AMI9", "url": "https://omabrowser.org/oma/group/A0A8V1AMI9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RJI2-1", "protein_name": "Rab5 GDP/GTP exchange factor", "gene_name": "RABGEF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKMFLESMHYKRDLSIEEQSECTQDFYQTVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKVTKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQESENWSPDACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAKEVQDIVEKYPLEIKPPNQSLAAIDSENVENDKLPPPLQPQVYAG", "length": 491 }, "evidence": [ { "id": "A0A8V1AMI9", "url": "https://omabrowser.org/oma/group/A0A8V1AMI9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9JM13-1", "protein_name": "Rab5 GDP/GTP exchange factor", "gene_name": "Rabgef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQRQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRAGSKKEIQEAKAPSPSINRQTSIETDRVTKEFIDFLKTFHKTGQEVYKQTKMFLEAMPYKRDLSIEEQSECTQDFYQNVAERMQTRGKVPPEKVEKIMDQIEKHIMTRLYKFVFCPETTDDEKKDLAIQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITRCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQESESWPPEACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAKEVQDIVEKYPLEIKPPNQPLAAIDSENVENDKLPPPLQPQVYAG", "length": 491 }, "evidence": [ { "id": "A0A8V1AMI9", "url": "https://omabrowser.org/oma/group/A0A8V1AMI9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJ41-2", "protein_name": "Rab5 GDP/GTP exchange factor", "gene_name": "RABGEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKLPPPLQPQVYAG", "length": 491 }, "evidence": [ { "id": "A0A8V1AMI9", "url": "https://omabrowser.org/oma/group/A0A8V1AMI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" }, { "name": "dendritic transport", "id": "GO:0098935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" }, { "id": "PS51036", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A20-type", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 52, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMI9" }, { "id": "PS51205", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51205" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VPS9", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 381, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 381, "end_pos": 383 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "negative regulation of actin filament bundle assembly", "id": "GO:0032232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP30" } ], "pmid": "" }, { "name": "cellular detoxification", "id": "GO:1990748", 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] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFS3", "url": "https://www.orthodb.org/?gene=A0A8V1AFS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMK2", "url": "https://www.orthodb.org/?gene=A0A8V1AMK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQD1", "url": "https://www.orthodb.org/?gene=A0A8V1AQD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10241:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10241:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRFLRPGHDPVRERLKRELFQFNKTVEHGFPHQPSALGYSPFLHLMAIGTRSGAIKLYGAPGVEFMGLHEENNTVMQIHFIPDQCQLVTLLDDNSLHLWSLKQHSGACELREDHHFTLKGPPGSPPSATQITAVLPHSAREVLYLGTESGNIFVVELPSFRVLEDKTITSEAVLQWTSEKVIFGPDVWIPEDYCSRRSCELVEALREHPKNPDQILIGYSRGLIVLWDRQNNKVTHHFLGSQQLENLYWQRDGSIFISCHYDGSYTRWPVSNDNRQSLPLENIVPYGPFPCKAISKIYWQTTRNGLPYVIFQGGMPRASYGDRHSISVIHGSQQTAFDFTSRVIDFFVIFSSEPTAESDDPSAMVVLAEEELIVIDLKSVGWPAVHPPYLASLHCSAITCSHHVSNIPLKLWERIISAGSKQNVHYSNMPWPIDGGTNIAPDPPQRDLLLTGHEDGTVRFWDASGVCLHLLYKLSTVRVFLTDADPNDNMNTVGEDEWPPLRKVGTFDPYSDDPRLGIQKIYLCKYSGYLAVAGTAGQVLVMELNDEDAEHVVDQVEADLLQDQEGYRWKGHEKLKIRDGPVRFEAGFQPFVLVQCQPPAVVTSLALHSEWKLVAFGTSHGFGLFDHQQKRLVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRIRRSRVSSRKRRGGGGNTSETHEANGKFEQDMLQEMELAPVQRKIEARSAEDSFTGFVRTLYFADTFLRDSSRHCPSLWAGTNGGTVFAFCLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVSVLVLDGRNIPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSSKLKLKLTALEGCRVRKVMVANFGSCKTDDYSENDLAVLTNLGDVQIISLPFLKLQIRYPCIRKEDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCVVDVPEVSSNNHMHSRSVMENASRKSRVSGRSSGDYGEDERNCGRLMDHALLNDEKVLREIQSTLEGGRGRDHIPTSQRNRTLTIRIQELCRKKFGKKSSRAQTK", "length": 1051, "header": "tr|A0A8V1AMK2-1|A0A8V1AMK2_CHICK Isoform 1 of LLGL scribble cell polarity complex component 2 OS=Gallus gallus OX=9031 GN=LLGL2 PE=1 SV=1 CANONICAL=A0A8V1AMK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2/entry#A0A8V1AFS3-1", "sequence": { "sequence": "MRRFLRPGHDPVRERLKRELFQFNKTVEHGFPHQPSALGYSPFLHLMAIGTRSGAIKLYGAPGVEFMGLHEENNTVMQIHFIPDQCQLVTLLDDNSLHLWSLKQHSGACELREDHHFTLKGPPGSPPSATQITAVLPHSAREVLYLGTESGNIFVVELPSFRVLEDKTITSEAVLQWTSEKVIFGPDVWIPEDYCSRRSCELVEALREHPKNPDQILIGYSRGLIVLWDRQNNKVTHHFLGSQQLENLYWQRDGSIFISCHYDGSYTRWPVSNDNRQSLPLENIVPYGPFPCKAISKIYWQTTRNGLPYVIFQGGMPRASYGDRHSISVIHGSQQTAFDFTSRVIDFFVIFSSEPTAESDDPSAMVVLAEEELIVIDLKSVGWPAVHPPYLASLHCSAITCSHHVSNIPLKLWERIISAGSKQNVHYSNMPWPIDGGTNIAPDPPQRDLLLTGHEDGTVRFWDASGVCLHLLYKLSTVRVFLTDADPNDNMNTVGEDEWPPLRKVGTFDPYSDDPRLGIQKIYLCKYSGYLAVAGTAGQVLVMELNDEDAEHVVDQVEADLLQDQEGYRWKGHEKLKIRDGPVRFEAGFQPFVLVQCQPPAVVTSLALHSEWKLVAFGTSHGFGLFDHQQKRLVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRIRRSRVSSRKRRGGGGNTSETHEANGKFEQDMLQEMELAPVQRKIEARSAEDSFTGFVRTLYFADTFLRDSSRHCPSLWAGTNGGTVFAFCLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVSVLVLDGRNIPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSSKLKLKLTALEGCRVRKVMVANFGSCKTDDYSENDLAVLTNLGDVQIISLPFLKLQIRYPCIRKEDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCVVDVPEVSSNNHMHSRSVMENASRKSRVSGRSSGDYGEDERNCGRLMDHALLNDEKVLREIQSTLEGGRGSYAERNLARSPVEHRLNNGGAD", "length": 1038, "header": "tr|A0A8V1AFS3-1|A0A8V1AFS3_CHICK Computationally mapped isoform of LLGL scribble cell polarity complex component 2 OS=Gallus gallus OX=9031 GN=LLGL2 PE=1 SV=1 CANONICAL=A0A8V1AMK2-1" }, "locus": { "chromosome": "18", "start_pos": 11559284, "end_pos": 11534995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072686.1", "url": "https://www.ensembl.org/id/ENSGALT00010072686.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044873.1", "url": "https://www.ensembl.org/id/ENSGALP00010044873.1" } ] } }, { "isoform_ac": "A0A8V1AMK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2/entry#A0A8V1AMK2-1", "sequence": { "sequence": "MRRFLRPGHDPVRERLKRELFQFNKTVEHGFPHQPSALGYSPFLHLMAIGTRSGAIKLYGAPGVEFMGLHEENNTVMQIHFIPDQCQLVTLLDDNSLHLWSLKQHSGACELREDHHFTLKGPPGSPPSATQITAVLPHSAREVLYLGTESGNIFVVELPSFRVLEDKTITSEAVLQWTSEKVIFGPDVWIPEDYCSRRSCELVEALREHPKNPDQILIGYSRGLIVLWDRQNNKVTHHFLGSQQLENLYWQRDGSIFISCHYDGSYTRWPVSNDNRQSLPLENIVPYGPFPCKAISKIYWQTTRNGLPYVIFQGGMPRASYGDRHSISVIHGSQQTAFDFTSRVIDFFVIFSSEPTAESDDPSAMVVLAEEELIVIDLKSVGWPAVHPPYLASLHCSAITCSHHVSNIPLKLWERIISAGSKQNVHYSNMPWPIDGGTNIAPDPPQRDLLLTGHEDGTVRFWDASGVCLHLLYKLSTVRVFLTDADPNDNMNTVGEDEWPPLRKVGTFDPYSDDPRLGIQKIYLCKYSGYLAVAGTAGQVLVMELNDEDAEHVVDQVEADLLQDQEGYRWKGHEKLKIRDGPVRFEAGFQPFVLVQCQPPAVVTSLALHSEWKLVAFGTSHGFGLFDHQQKRLVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRIRRSRVSSRKRRGGGGNTSETHEANGKFEQDMLQEMELAPVQRKIEARSAEDSFTGFVRTLYFADTFLRDSSRHCPSLWAGTNGGTVFAFCLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVSVLVLDGRNIPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSSKLKLKLTALEGCRVRKVMVANFGSCKTDDYSENDLAVLTNLGDVQIISLPFLKLQIRYPCIRKEDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCVVDVPEVSSNNHMHSRSVMENASRKSRVSGRSSGDYGEDERNCGRLMDHALLNDEKVLREIQSTLEGGRGRDHIPTSQRNRTLTIRIQELCRKKFGKKSSRAQTK", "length": 1051, "header": "tr|A0A8V1AMK2-1|A0A8V1AMK2_CHICK Isoform 1 of LLGL scribble cell polarity complex component 2 OS=Gallus gallus OX=9031 GN=LLGL2 PE=1 SV=1 CANONICAL=A0A8V1AMK2-1" }, "locus": { "chromosome": "18", "start_pos": 11558582, "end_pos": 11534995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072685.1", "url": "https://www.ensembl.org/id/ENSGALT00010072685.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044872.1", "url": "https://www.ensembl.org/id/ENSGALP00010044872.1" } ] } }, { "isoform_ac": "A0A8V1AQD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2/entry#A0A8V1AQD1-1", "sequence": { "sequence": "MRECAALNQPGAGFLVQAGTMRRFLRPGHDPVRERLKRELFQFNKTVEHGFPHQPSALGYSPFLHLMAIGTRSGAIKLYGAPGVEFMGLHEENNTVMQIHFIPDQCQLVTLLDDNSLHLWSLKQHSGACELREDHHFTLKGPPGSPPSATQITAVLPHSAREVLYLGTESGNIFVVELPSFRVLEDKTITSEAVLQWIPEDYCSRRSCELVEALREHPKNPDQILIGYSRGLIVLWDRQNNKVTHHFLGSQQLENLYWQRDGSIFISCHYDGSYTRWPVSNDNRQSLPLENIVPYGPFPCKAISKIYWQTTRNGLPYVIFQGGMPRASYGDRHSISVIHGSQQTAFDFTSRVIDFFVIFSSEPTAESDDPSAMVVLAEEELIVIDLKSVGWPAVHPPYLASLHCSAITCSHHVSNIPLKLWERIISAGSKQNVHYSNMPWPIDGGTNIAPDPPQRDLLLTGHEDGTVRFWDASGVCLHLLYKLSTVRVFLTDADPNDNMNTVGEDEWPPLRKVGTFDPYSDDPRLGIQKIYLCKYSGYLAVAGTAGQVLVMELNDEDAEHVVDQVEADLLQDQEGYRWKGHEKLKIRDGPVRFEAGFQPFVLVQCQPPAVVTSLALHSEWKLVAFGTSHGFGLFDHQQKRLVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRIRRSRVSSRKRRGGGGNTSETHEANGKFEQDMLQEMELAPVQRKIEARSAEDSFTGFVRTLYFADTFLRDSSRHCPSLWAGTNGGTVFAFCLRVPPAERRMDEPVRAEQAKEIQLMHRAPVVSVLVLDGRNIPLPEPLEVAHDLSKSPDMQGSHQLLVVSEEQFKVFTLPKVSSKLKLKLTALEGCRVRKVMVANFGSCKTDDYSENDLAVLTNLGDVQIISLPFLKLQIRYPCIRKEDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCVVDVPEVSSNNHMHSRSVMENASRKSRVSGRSSGDYGEDERNCGRLMDHALLNDEKVLREIQSTLEGGRG", "length": 1024, "header": "tr|A0A8V1AQD1-1|A0A8V1AQD1_CHICK Computationally mapped isoform of LLGL scribble cell polarity complex component 2 OS=Gallus gallus OX=9031 GN=LLGL2 PE=1 SV=1 CANONICAL=A0A8V1AMK2-1" }, "locus": { "chromosome": "18", "start_pos": 11557794, "end_pos": 11528463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072687.1", "url": "https://www.ensembl.org/id/ENSGALT00010072687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044874.1", "url": "https://www.ensembl.org/id/ENSGALP00010044874.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "establishment of spindle orientation", "id": "GO:0051294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051294", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "regulation of establishment or maintenance of cell polarity", "id": "GO:0032878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032878", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "L-leucine transport", "id": "GO:0015820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015820", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "myosin II binding", "id": "GO:0045159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton", "id": "GO:0030864", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030864", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 967, "end_pos": 969, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK2" }, { "id": "PF08366", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08366" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lethal giant larvae homologue 2", "eco_id": "ECO_0000259", "start_pos": 285, "end_pos": 384, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1026, "end_pos": 1028 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 967, "end_pos": 969 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AML5-1", "uniprot_ac": "A0A8V1AML5", "uniprot_id": "A0A8V1AML5_CHICK", "mass": { "chemical_mass": 55720.0, "monoisotopic_mass": 55720.0 }, "refseq": { "ac": "XP_015151390", "name": "E3 ubiquitin-protein ligase TRIM50", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151390" }, "gene_names": [ { "name": "TRIM50", "type": "recommended", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "name": "TRIM50", "type": "synonym", "evidence": [ { "id": "XP_015151390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151390" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase TRIM50", "type": "synonym", "evidence": [ { "id": "XP_015151390", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151390" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151390.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151390" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM50", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5", "locus": { "chromosome": "19", "start_pos": 838283, "end_pos": 832640, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029540", "url": "https://www.ensembl.org/id/ENSGALG00010029540" } ] } } ], "crossref": [ { "id": "A0A8V1AML5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AML5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16605", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16605", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417461", "url": "https://www.ncbi.nlm.nih.gov/gene/417461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417461", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVCWHER", "url": "https://omabrowser.org/oma/group/DVCWHER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AML5", "url": "https://www.orthodb.org/?gene=A0A8V1AML5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015151390", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151390", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AML5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARKMSIDNLEDQLLCPICLEVFKEPLMLQCGHSYCKSCVLSLSGELDEQLLCPVCRKSVDCSASPPNVTLARIIEALQSRGETEPTPESCPTHDNPLSLFCEADREVICGLCGTIGNHKQHKITPISTAYCRMKEELSVLLTDVHRCKRNLDELFSKLINNKIRIANEADVFKWVIRKEFEELHRYIDEEKATFLESVEGKAAQLITSIESQVKQTSDTLQRLKEMQSILETLGNESQLDFIRKYSSYQFRSELPSLHPGDTIFSPVSFKPCFHQDDIKMTVWKRLHRHVLPAPEMLKLDPVTAHPLLELFKGDTVVQCGLYQRRDSNPKRFDSSNCILTCKGFSCGQHYWEVIVGTRNHWRVGIIKGTVSRKGKLSKSPENGVWLIGLKEGKVYEAFSTPRATLPLTARPQRIGIYLHYEKGELTFYNADSPDELSPIYTFQAEFQGQLYPIVDLCWPERGPFSPPIILPAPAAGRHSQGPPAAEEPTKL", "length": 492, "header": "tr|A0A8V1AML5-1|A0A8V1AML5_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM50 PE=3 SV=1 CANONICAL=A0A8V1AML5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AML5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5/entry#A0A8V1AML5-1", "sequence": { "sequence": "MARKMSIDNLEDQLLCPICLEVFKEPLMLQCGHSYCKSCVLSLSGELDEQLLCPVCRKSVDCSASPPNVTLARIIEALQSRGETEPTPESCPTHDNPLSLFCEADREVICGLCGTIGNHKQHKITPISTAYCRMKEELSVLLTDVHRCKRNLDELFSKLINNKIRIANEADVFKWVIRKEFEELHRYIDEEKATFLESVEGKAAQLITSIESQVKQTSDTLQRLKEMQSILETLGNESQLDFIRKYSSYQFRSELPSLHPGDTIFSPVSFKPCFHQDDIKMTVWKRLHRHVLPAPEMLKLDPVTAHPLLELFKGDTVVQCGLYQRRDSNPKRFDSSNCILTCKGFSCGQHYWEVIVGTRNHWRVGIIKGTVSRKGKLSKSPENGVWLIGLKEGKVYEAFSTPRATLPLTARPQRIGIYLHYEKGELTFYNADSPDELSPIYTFQAEFQGQLYPIVDLCWPERGPFSPPIILPAPAAGRHSQGPPAAEEPTKL", "length": 492, "header": "tr|A0A8V1AML5-1|A0A8V1AML5_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM50 PE=3 SV=1 CANONICAL=A0A8V1AML5-1" }, "locus": { "chromosome": "19", "start_pos": 838066, "end_pos": 834087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071408.1", "url": "https://www.ensembl.org/id/ENSGALT00010071408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044098.1", "url": "https://www.ensembl.org/id/ENSGALP00010044098.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 87, "start_aa": "Thr", "end_pos": 87, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr87", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417461", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HLW0-1", "protein_name": "E3 ubiquitin-protein ligase TRIM50", "gene_name": "Trim50", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAWRVTVPELHDQLQCPICLEVFKEPLMLQCGHSYCKGCLDSLSQHLDSELRCPVCRQSVDCSSSLPNVSLARVIDALRLPGDTEPTVCVHHRNPLSLFCEKDQEFICGLCGLLGSHQHHRVTPVSTVYSRMKEELAGRISEVKEEQRKVEEHIGKLVNNRTRIMNESDVFSWVIRREFQELHHLVDEEKARCLEGVEGHTRGLVASLDMQLEQAQGTQERLAQAEQVLEQFGNESHHEFIRKFYSMVSRAEVQQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPESLKLDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASKGFSWGRHYWEVVVGSKSDWRLGVIKGTASRKGKLSKSPEHGVWLIGLKEGRVYEAFGCPRLPLPVAGHPHRIGVYLHYEQGELTFFDADHPDDLRTLYTFQADFQGKLYPILDTCWHERGSNSLPMVLPPPSGPGYLRPAQL", "length": 484 }, "evidence": [ { "id": "A0A8V1AML5", "url": "https://omabrowser.org/oma/group/A0A8V1AML5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q810I2-1", "protein_name": "E3 ubiquitin-protein ligase TRIM50", "gene_name": "Trim50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWRLTVPELQDQLQCPICLEVFKEPLMLQCGHSYCKDCLDNLSQHLDSELCCPVCRQSVDCSSSPPNVSLARVIDALRLPGDIEPTVCVHHRNPLSLFCEKDQEFICGLCGLLGSHQHHRVTPVSTVYSRMKEELAGRISELKEEHRNVEEHIGKLVNNRTRIINESDVFSWVIRREFQELHHLVDEEKARCLEGLEGHTRGLVASLDMQLEQAQGTQERLAQAEQVLEQFGNESHHEFIRFHSVASRAEVQQARPLEGVFSPISFKPALHQADIKLTVWKRLFRKVLPAPASLKLDPATAHPLLELSKGNTVVHCGLLAQRRASQPERFDYSTCVLASKGFSWGRHYWEVVVGSKSDWRLGVIKGTASRKGKLNKSPEHGVWLIGLKEGRVYEAFGCPRLPLPVAGHPHRIGVYLHYEQGELTFFDADRPDDLRTLYTFQADFQGKLYPILDTCWHERGSNSLPMVLPPPSGPGHFTLGQV", "length": 483 }, "evidence": [ { "id": "A0A8V1AML5", "url": "https://omabrowser.org/oma/group/A0A8V1AML5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86XT4-1", "protein_name": "E3 ubiquitin-protein ligase TRIM50", "gene_name": "TRIM50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAWQVSLPELEDRLQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKFIRKFHSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYWEVVVGSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLPMVLPPPSGPGPLSPEQPTKL", "length": 487 }, "evidence": [ { "id": "A0A8V1AML5", "url": "https://omabrowser.org/oma/group/A0A8V1AML5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AML5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", 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ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { 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"https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KSR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60", "locus": { "chromosome": "19", "start_pos": 9673586, "end_pos": 9618146, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029549", "url": "https://www.ensembl.org/id/ENSGALG00010029549" } ] } } ], "crossref": [ { "id": "A0A8V1AP60", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP60", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMM9", "url": "https://www.orthodb.org/?gene=A0A8V1AMM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP58", "url": "https://www.orthodb.org/?gene=A0A8V1AP58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP60", "url": "https://www.orthodb.org/?gene=A0A8V1AP60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23257:SF716", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23257:SF716", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5673000", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5674135", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AMM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AMM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP58", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRAAALRAAGMLERKERGGEAAGPAVRGLPAVRSTLQQCGLLQDLIDISLSNLRGLRTKCAASNDLTQQEIRTLEVKLIDYIHRQRQCKLSVPLNDRTAELNSYPRFNDWLDIVNVRKEVVQRIPEELTLDALLEMNESKVKETMKRCGARDEECSRLNGALSCLRKVTESGGELKDDVLTNLSEVRRENSSTNMTESPCSSAPTWTHSALSLPKGNSQQARSVSVSTIPSSDSLASSHGPSIYADNLLDPFAFPAHSGRLTPRTPHSITVTPPTTPQAKRRHKLKPPRTPPPPCRKVFQLLPNFPTLTRSKSHESQLGNRIDDVPPIKSLCSPSELSQGSPQMVRRDFGLAVTHRFSTKSWLSQICQVCQKSMMFGVKCKYCRLKCHNKCTKEAPACRISFLPITKIRRTESVPSDINNPVDRPTEPQFGTLPKALTKKEHPPAINHLDSSSNPSSTTSSTPSSPAPFQSSNPPSATPPPNLSPMGQRDGRFNFPGKPIFFWRTLPRSERHLWKLSQIGTSTYPSPLKTDSQHVFPFSFCKQVEEPESNKSEPEDDEDEVEDLPNRRPHLQGMIYRKPSQTSVYLQEWDIPFEQIELGDPIGQGRWGKVHKGKWHGEVAIRLLEIDGNNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLYSFVRDPKISLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVQEGRRENELKLPHDWLCYLAPEIVREMAPGKDEDKLPFSKAADIYAFGTVWYELQAREWPFKNQPAEALIWQIGSGEGVKQILATISLGKEINEILSACWSFDLSERPSFTVLMDMLEKLPKLNRRLSHPGHFWKSADINSSKVVLRFERFGLGILEPSNQKI", "length": 907, "header": "tr|A0A8V1AP60-1|A0A8V1AP60_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=KSR1 PE=3 SV=1 CANONICAL=A0A8V1AP60-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AMM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60/entry#A0A8V1AMM9-1", "sequence": { "sequence": "MDRAAALRAAGMLERKERGGEAAGPAVRGLPAVRSTLQQCGLLQDLIDISLSNLRGLRTKCAASNDLTQQEIRTLEVKLIDYIHRQRQCKLSVPLNDRTAELNSYPRFNDWLDIVNVRKEVVQRIPEELTLDALLEMNESKVKETMKRCGARDEECSRLNGALSCLRKVTESGGELKDDVLTNLSEVRRENSSTNMTESPCSSAPTWTHSALSLPKGNSQQARSVSVSTIPSSDSLASSHGPSIYADNLLDPFAFPAHSGRLTPRTPHSITVTPPTTPQAKRRHKLKPPRTPPPPCRKVFQLLPNFPTLTRSKSHESQLGNRIDDVPPIKSLCSPSELSQGSPQMVRRDFGLAVTHRFSTKSWLSQICQVCQKSMMFGVKCKYCRLKCHNKCTKEAPACRISFLPITKIRRTESVPSDINNPVDRPTEPQFGTLPKALTKKEHPPAINHLDSSSNPSSTTSSTPSSPAPFQSSNPPSATPPPNLSPMGQRDGRFNFPAAYYIQHRQQFIFPDSQHVFPFSFCKQVEEPESNKSEPEDDEDEVEDLPNRRPHLQGMIYRKPSQTSVYLQEWDIPFEQIELGDPIGQGRWGKVHKGKWHGEVAIRLLEIDGNNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLYSFVRDPKISLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVQEGRRENELKLPHDWLCYLAPEIVREMAPGKDEDKLPFSKAADIYAFGTVWYELQAREWPFKNQPAEALIWQIGSGEGVKQILATISLGKEINEILSACWSFDLSERPSFTVLMDMLEKLPKLNRRLSHPGHFWKSSSTHLRLGTFKASCFANLSHIINSSKVVLRFERFGLGILEPSNQKI", "length": 906, "header": "tr|A0A8V1AMM9-1|A0A8V1AP60_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=KSR1 PE=3 SV=1 CANONICAL=A0A8V1AP60-1" }, "locus": { "chromosome": "19", "start_pos": 9673003, "end_pos": 9618279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071428.1", "url": "https://www.ensembl.org/id/ENSGALT00010071428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044118.1", "url": "https://www.ensembl.org/id/ENSGALP00010044118.1" } ] } }, { "isoform_ac": "A0A8V1AP58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60/entry#A0A8V1AP58-1", "sequence": { "sequence": "MDRAAALRAAGMLERKERGGEAAGPAVRGLPAVRSTLQQCGLLQDLIDISLSNLRGLRTKCAASNDLTQQEIRTLEVKLIDYIHRQRQCKLSVPLNDRTAELNSYPRFNDWLDIVNVRKEVVQRIPEELTLDALLEMNESKVKETMKRCGARDEECSRLNGALSCLRKVTESGGELKDDVLTNLSEVRRENSSTNMTDLPKGNSQQARSVSVSTIPSSDSLASSHGPSIYADNLLDPFAFPAHSGRLTPRTPHSITVTPPTTPQAKRRHKLKPPRTPPPPCRKVFQLLPNFPTLTRSKSHESQLGNRIDDVPPIKSLCSPSELSQGSPQMVRRDFGLAVTHRFSTKSWLSQICQVCQKSMMFGVKCKYCRLKCHNKCTKEAPACRISFLPITKIRRTESVPSDINNPVDRPTEPQFGTLPKALTKKEHPPAINHLDSSSNPSSTTSSTPSSPAPFQSSNPPSATPPPNLSPMGQRDGRFNFPGKPIFFWRTLPRSERHLWKLSNKSEPEDDEDEVEDLPNRRPHLQGMIYRKPSQTSVYLQEWDIPFEQIELGDPIGQGRWGKVHKGKWHGEVAIRLLEIDGNNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLYSFVRDPKISLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVQEGRRENELKLPHDWLCYLAPEIVREMAPGKDEDKLPFSKAADIYAFGTVWYELQAREWPFKNQPAEALIWQIGSGEGVKQILATISLGKEINEILSACWSFDLSERPSFTVLMDMLEKLPKLNRRLSHPGHFWKSAE", "length": 835, "header": "tr|A0A8V1AP58-1|A0A8V1AP58_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=KSR1 PE=3 SV=1 CANONICAL=A0A8V1AP60-1" }, "locus": { "chromosome": "19", "start_pos": 9668432, "end_pos": 9618279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071426.1", "url": "https://www.ensembl.org/id/ENSGALT00010071426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044116.1", "url": "https://www.ensembl.org/id/ENSGALP00010044116.1" } ] } }, { "isoform_ac": "A0A8V1AP60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60/entry#A0A8V1AP60-1", "sequence": { "sequence": "MDRAAALRAAGMLERKERGGEAAGPAVRGLPAVRSTLQQCGLLQDLIDISLSNLRGLRTKCAASNDLTQQEIRTLEVKLIDYIHRQRQCKLSVPLNDRTAELNSYPRFNDWLDIVNVRKEVVQRIPEELTLDALLEMNESKVKETMKRCGARDEECSRLNGALSCLRKVTESGGELKDDVLTNLSEVRRENSSTNMTESPCSSAPTWTHSALSLPKGNSQQARSVSVSTIPSSDSLASSHGPSIYADNLLDPFAFPAHSGRLTPRTPHSITVTPPTTPQAKRRHKLKPPRTPPPPCRKVFQLLPNFPTLTRSKSHESQLGNRIDDVPPIKSLCSPSELSQGSPQMVRRDFGLAVTHRFSTKSWLSQICQVCQKSMMFGVKCKYCRLKCHNKCTKEAPACRISFLPITKIRRTESVPSDINNPVDRPTEPQFGTLPKALTKKEHPPAINHLDSSSNPSSTTSSTPSSPAPFQSSNPPSATPPPNLSPMGQRDGRFNFPGKPIFFWRTLPRSERHLWKLSQIGTSTYPSPLKTDSQHVFPFSFCKQVEEPESNKSEPEDDEDEVEDLPNRRPHLQGMIYRKPSQTSVYLQEWDIPFEQIELGDPIGQGRWGKVHKGKWHGEVAIRLLEIDGNNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLYSFVRDPKISLDINKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVQEGRRENELKLPHDWLCYLAPEIVREMAPGKDEDKLPFSKAADIYAFGTVWYELQAREWPFKNQPAEALIWQIGSGEGVKQILATISLGKEINEILSACWSFDLSERPSFTVLMDMLEKLPKLNRRLSHPGHFWKSADINSSKVVLRFERFGLGILEPSNQKI", "length": 907, "header": "tr|A0A8V1AP60-1|A0A8V1AP60_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=KSR1 PE=3 SV=1 CANONICAL=A0A8V1AP60-1" }, "locus": { "chromosome": "19", "start_pos": 9673003, "end_pos": 9618279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071431.1", "url": "https://www.ensembl.org/id/ENSGALT00010071431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044121.1", "url": "https://www.ensembl.org/id/ENSGALP00010044121.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 463, "start_aa": "Thr", "end_pos": 463, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr463", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 479, "start_aa": "Thr", "end_pos": 479, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr479", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5673000", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "resource": "Reactome", "description": "RAF activation" }, { "id": "R-GGA-5674135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674135", "resource": "Reactome", "description": "MAP2K and MAPK activation" }, { "id": "R-GGA-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "mitogen-activated protein kinase kinase binding", "id": "GO:0031434", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031434", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "MAP-kinase scaffold activity", "id": "GO:0005078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" }, { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP60", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", 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"A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", 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"A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", 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"E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-5672948", "name": "MARK3 phosphorylates KSR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5672948", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672948" } ] }, { "id": "R-GGA-5672950", "name": "Activator\" RAF:YWHAB dimer binds RAS:GTP\"", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672950", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672950" } ] }, { "id": "R-GGA-5672954", "name": "p-S311,S406 KSR1:MARK3 binds YWHAB dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5672954", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672954" } ] }, { "id": "R-GGA-5672958", "name": "YWHAB dimer dissociates from KSR1:MARK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5672958", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672958" } ] }, { "id": "R-GGA-5672966", "name": "RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0ZZ54-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672966", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672966" } ] }, { "id": "R-GGA-5672969", "name": "Phosphorylation of RAF", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "A0A8V0YNY4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672969", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672969" } ] }, { "id": "R-GGA-5672973", "name": "MAP2Ks phosphorylate MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672973", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672973" } ] }, { "id": "R-GGA-5672978", "name": "RAF phosphorylates MAP2K dimer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5672978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5672978" } ] }, { "id": "R-GGA-5674019", "name": "BRAP binds KSR1:MARK3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AP60-1", "A0A8V0ZZ54-1", "A0A8V0YLV1-1" ], "evidence": [ { "id": "R-GGA-5674019", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5674019" } ] }, { "id": "R-GGA-5675417", "name": "PEBP1 binds activated RAF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-5675417", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5675417" } ] }, { "id": "R-GGA-9653108", "name": "Raf dimer inhibitors bind RAF heterodimers", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F352-1", "A0A8V1AP60-1", "P05625-1", "P08642-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9653108", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9653108" } ] }, { "id": "R-GGA-9657599", "name": "Dual mechanism MAP2K inhibitors bind MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657599", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657599" } ] }, { "id": "R-GGA-9657603", "name": "Dual mechanism MAPK inhibitors bind MAPKs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657603", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657603" } ] }, { "id": "R-GGA-9657606", "name": "Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657606", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657606" } ] }, { "id": "R-GGA-9657608", "name": "Single mechanism MAPK inhibitors bind phosphorylated MAPK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P53478-1", "Q5F352-1", "A0A1D5PX90-1", "Q5ZHX1-1", "A0A8V1AP60-1", "A0A8V0ZND5-1", "F1NSA8-1", "A0A8V1A4Q4-1", "A0A8V0ZDU6-1", "P05625-1", "P08642-1", "Q5ZMQ2-1", "A0A8V0YLV1-1", "A0A8V0YMN5-1" ], "evidence": [ { "id": "R-GGA-9657608", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9657608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] } ] }, { "uniprot_ac": "A0A3Q2TY19", "gene_name": "MAPK8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] } ] }, { "uniprot_ac": "A0A3Q2U9U9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] } ] }, { "uniprot_ac": "A0A3Q2UF44", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] } ] }, { "uniprot_ac": "A0A3Q2UI52", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YNY4", "gene_name": "JAK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YNY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNY4" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": 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"A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP 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1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND5", "gene_name": "CSK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0ZND5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND5" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZ54", "gene_name": "BRAP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZZ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ54" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NSA8", "gene_name": "RAP1A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "F1NSA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSA8" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": 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"url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" 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"mass": { "chemical_mass": 31026.0, "monoisotopic_mass": 31026.0 }, "refseq": { "ac": "XP_040543035", "name": "complement component 1 Q subcomponent-binding protein, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543035" }, "gene_names": [ { "name": "C1QBP", "type": "recommended", "evidence": [ { "id": "A0A8V1AMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMS0" } ] }, { "name": "C1QBP", "type": "synonym", "evidence": [ { "id": "XP_040543035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543035" } ] } ], "protein_names": [ { "name": "Complement component 1 Q subcomponent-binding protein, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V1AMS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMS0/entry#names_and_taxonomy" } ] }, { "name": "complement component 1 Q subcomponent-binding protein, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040543035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543035" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052591.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040543035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040543035" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMS0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1QBP", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMS0", "locus": { "chromosome": "19", "start_pos": 3918175, "end_pos": 3915262, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029248", "url": "https://www.ensembl.org/id/ENSGALG00010029248" } ] } } ], "crossref": [ { "id": "A0A8V1AMS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AMS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "395538", "url": "https://www.ncbi.nlm.nih.gov/gene/395538", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AMS0", "url": "https://www.orthodb.org/?gene=A0A8V1AMS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10826", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10826", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10826:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10826:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02330", "url": 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"spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "protein kinase C inhibitor activity", "id": "GO:0008426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AMZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AMZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMZ8" }, { "id": "PS01031", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SHSP", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 184, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, 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homolog 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025884" }, "gene_names": [ { "name": "NIPSNAP2", "type": "recommended", "evidence": [ { "id": "A0A8V1AN48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ] }, { "name": "GBAS", "type": "synonym", "evidence": [ { "id": "NP_001025884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025884" } ] }, { "name": "NIPSNAP2", "type": "synonym", "evidence": [ { "id": "NP_001025884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025884" } ] } ], "protein_names": [ { "name": "Nipsnap homolog 2", "type": "synonym", "evidence": [ { "id": "A0A8V1AN48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48/entry#names_and_taxonomy" } ] }, { "name": "glioblastoma amplified sequence", "type": "synonym", "evidence": [ { "id": "NP_001025884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025884" } ] }, { "name": "protein NipSnap homolog 2", "type": "synonym", "evidence": [ { "id": "NP_001025884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025884" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720622.1, HAEK01040183.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1. On Oct 28, 2021 this sequence version replaced NP_001025884.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025884" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIPSNAP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48", "locus": { "chromosome": "19", "start_pos": 5370390, "end_pos": 5339977, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029648", "url": "https://www.ensembl.org/id/ENSGALG00010029648" } ] } } ], "crossref": [ { "id": "A0A8V1AN48", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AN48", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002388", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002388", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417539", "url": "https://www.ncbi.nlm.nih.gov/gene/417539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417539", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REKSWSV", "url": "https://omabrowser.org/oma/group/REKSWSV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN48", "url": "https://www.orthodb.org/?gene=A0A8V1AN48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NZ68", "url": "https://www.orthodb.org/?gene=F1NZ68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21017:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21017:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013407", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001025884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025884", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ68", "url": "https://www.uniprot.org/uniprotkb/F1NZ68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NZ68-1", "url": "https://www.uniprot.org/uniprotkb/F1NZ68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARVLLRWSPAGAGAVPRLPPGGSLAVRGMVSSASRPREDSWLKSLFVRKVDPRKDAHSNLLAKRETSSLYKLQIHNVKPECLEAYNKLCQEVLPKIHEEKHYPCALVGTWNTWYGEQDQAVHLWRYEGGYPALNEVMSKLRQNKEFTEFRKERGNMLLSRKNQLLLEFSFWNEPVPREGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAVGGFFSQIGQLYMVHHLWAYKDLQTREDIRNAAWHKPGWDELVYYTVPLIQEMESRIMIPLKISPLQ", "length": 284, "header": "tr|A0A8V1AN48-1|A0A8V1AN48_CHICK Isoform 1 of Nipsnap homolog 2 OS=Gallus gallus OX=9031 GN=NIPSNAP2 PE=1 SV=1 CANONICAL=A0A8V1AN48-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AN48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48/entry#A0A8V1AN48-1", "sequence": { "sequence": "MAARVLLRWSPAGAGAVPRLPPGGSLAVRGMVSSASRPREDSWLKSLFVRKVDPRKDAHSNLLAKRETSSLYKLQIHNVKPECLEAYNKLCQEVLPKIHEEKHYPCALVGTWNTWYGEQDQAVHLWRYEGGYPALNEVMSKLRQNKEFTEFRKERGNMLLSRKNQLLLEFSFWNEPVPREGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAVGGFFSQIGQLYMVHHLWAYKDLQTREDIRNAAWHKPGWDELVYYTVPLIQEMESRIMIPLKISPLQ", "length": 284, "header": "tr|A0A8V1AN48-1|A0A8V1AN48_CHICK Isoform 1 of Nipsnap homolog 2 OS=Gallus gallus OX=9031 GN=NIPSNAP2 PE=1 SV=1 CANONICAL=A0A8V1AN48-1" }, "locus": { "chromosome": "19", "start_pos": 5366949, "end_pos": 5340320, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071684.1", "url": "https://www.ensembl.org/id/ENSGALT00010071684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044374.1", "url": "https://www.ensembl.org/id/ENSGALP00010044374.1" } ] } }, { "isoform_ac": "F1NZ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48/entry#F1NZ68-1", "sequence": { "sequence": "MRTAAASGAWLEDPPHPGAVCAPLGRRRRYSARPPPPAPAQEGGGRSKMAARVLLRWSPAGAGAVPRLPPGGSLAVRGMVSSASRPREDSWLKSLFVRKVDPRKDAHSNLLAKRETSSLYKLQIHNVKPECLEAYNKLCQEVLPKIHEEKHYPCALVGTWNTWYGEQDQAVHLWRYEGGYPALNEVMSKLRQNKEFTEFRKERGNMLLSRKNQLLLEFSFWNEPVPREGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAVGGFFSQIGQLYMVHHLWAYKDLQTREDIRNAAWHKPGWDELVYYTVPLIQEMESRIMIPLKISPLQ", "length": 332, "header": "tr|F1NZ68-1|F1NZ68_CHICK Computationally mapped isoform of Nipsnap homolog 2 OS=Gallus gallus OX=9031 GN=NIPSNAP2 PE=1 SV=2 CANONICAL=A0A8V1AN48-1" }, "locus": { "chromosome": "19", "start_pos": 5353189, "end_pos": 5340176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071683.1", "url": "https://www.ensembl.org/id/ENSGALT00010071683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044373.1", "url": "https://www.ensembl.org/id/ENSGALP00010044373.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417539", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013407", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013407", "resource": "Reactome", "description": "RHOH GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABB8-1", "protein_name": "Nipsnap homolog 2", "gene_name": "NIPSNAP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAARVLRAGGAASGGGFLWRAAPCSLLPGLRKLASSNNRLREESWLKSLFVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLKENQEFSRFRKERSNMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGELYMVHHLWAYKDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPQKTSPLQ", "length": 286 }, "evidence": [ { "id": "A0A8V1AN48", "url": "https://omabrowser.org/oma/group/A0A8V1AN48/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O55126-1", "protein_name": "Protein NipSnap homolog 2", "gene_name": "Nipsnap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARVLLARGGLLRPAAQSAFLPGLRTVTSSSHRAREDSWLKSLFVRKVDPRKDAHSNLLAKKETSSLYKLQFHNVKPECLDAYNKICQEVLPKIHEGKQYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLKENQEFVNFRKARSDMLLSRKNQLLLEFSFWNEPVPRPGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDSNEAIGGFFSQIGQLYMVDHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ", "length": 281 }, "evidence": [ { "id": "A0A8V1AN48", "url": "https://omabrowser.org/oma/group/A0A8V1AN48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75323-1", "protein_name": "Protein NipSnap homolog 2", "gene_name": "NIPSNAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ", "length": 286 }, "evidence": [ { "id": "A0A8V1AN48", "url": "https://omabrowser.org/oma/group/A0A8V1AN48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54I58-1", "protein_name": "Protein NipSnap homolog", "gene_name": "nipsnap", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFRNLINQSIRNYSTTTNVATKTKVYELKTYNILANNIPSFFELLGENKGSNSLGTWVTEMGSSNQVISLVEHESLDDRQMNEWNTKFQSKAAKLIEKQESLILREFPWAPFQKISNEKSNENKVWELRTYQSKPGKLGQWAIDFTTGFAERKKISEPVGVFYSEFGPLNTIVHLWPYKSFEDRFRIRDLALKNPVWVETVAKTTANLDSMESKTIIPVKL", "length": 223 }, "evidence": [ { "id": "A0A8V1AN48", "url": "https://omabrowser.org/oma/group/A0A8V1AN48/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VXK0-1", "protein_name": "Protein NipSnap", "gene_name": "Nipsnap", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKLRNLLAVGKSNNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKEIIYALHTHNVRPDSMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLRSRHLQYLLAFSYWPQIASRTGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSPSQ", "length": 273 }, "evidence": [ { "id": "A0A8V1AN48", "url": "https://omabrowser.org/oma/group/A0A8V1AN48/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN48", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AN48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN48" }, { "id": "PF07978", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NIPSNAP", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 282, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AN63-1", "uniprot_ac": "A0A8V1AN63", "uniprot_id": "A0A8V1AN63_CHICK", "mass": { "chemical_mass": 80693.0, "monoisotopic_mass": 80693.0 }, "refseq": {}, "gene_names": [ { "name": "NOL11", "type": "recommended", "evidence": [ { "id": "A0A8V1AN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" } ] } ], "protein_names": [ { "name": "Nucleolar protein 11", "type": "synonym", "evidence": [ { "id": "A0A8V1AN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOL11", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63", "locus": { "chromosome": "18", "start_pos": 7678293, "end_pos": 7691284, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029323", "url": "https://www.ensembl.org/id/ENSGALG00010029323" } ] } } ], "crossref": [ { "id": "A0A8V1AN63", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AN63", "database": "AlphaFoldDB", "categories": [] }, { "id": "417423", "url": "https://www.ncbi.nlm.nih.gov/gene/417423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417423", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGTTGQC", "url": "https://omabrowser.org/oma/group/QGTTGQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AN63", "url": "https://www.orthodb.org/?gene=A0A8V1AN63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15633:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15633:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006210", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AN63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALCEAFTLCGLGPAGGVGLGSGLLALEPGADPDHVLLTDRGRTTTLFKVSDQKPLGCWSVKHGQIITCPVVCNFETHEYIAVHDNKVLRIWKDEDVNLDKVFKATLSAEVYRIHSLPHAEPLVLFKGGGVRTLDVLLEAPQQEIENVISDEVIKWSEAFLESRQPVLIFVTEKDGDFFVYVQKPKMRSLHKYKLEQQELCNPLSFTAYIKKQIITLLCLYSSDSVYKVLIPLQQSSEEEEQTLSKSLLLNLSISGSVLKGTSFVVLDKDHVAVLGSLAASGEESKECLTIWNTKFQTLQASKELPLGTSGQLWCYGEKFFFTHGKVLTVVIYKCETSSLAAAVGKLKDSQTSDLSSFVNWNTLGDEELLVSLQSQQSVALKSESKMTLRSKKSTVANIQPDTSTVGQFLLSIKDASTAAVEDQLRQLLSKAQMPDFQAAIGCIISALINRCKTDPKFYPRNFLVQMIQKGELSYSLCPDLMAVALEKKDVHLLQICLQRFPDIPEEITYACLKVFLSISDDYLERTDVNLESVISYIDIEPNNKEVKTEVVENGFSTELEEDGCDVTGMKETHMMDSVEFCPVGPQKAALLNAVLHSAYSETFLLPHLKDLPAQQAVLFLRYLHYLYVKCSEKINTTLPGILSPTISQIMDWMCLLLDAHFTVMVMLPEAKGLLSSMHRFVRAQVRLYSELNKIEGSLQELQRIKCQKHSQAYSIEVLELI", "length": 723, "header": "tr|A0A8V1AN63-1|A0A8V1AN63_CHICK Isoform 1 of Nucleolar protein 11 OS=Gallus gallus OX=9031 GN=NOL11 PE=1 SV=1 CANONICAL=A0A8V1AN63-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AN63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63/entry#A0A8V1AN63-1", "sequence": { "sequence": "MAALCEAFTLCGLGPAGGVGLGSGLLALEPGADPDHVLLTDRGRTTTLFKVSDQKPLGCWSVKHGQIITCPVVCNFETHEYIAVHDNKVLRIWKDEDVNLDKVFKATLSAEVYRIHSLPHAEPLVLFKGGGVRTLDVLLEAPQQEIENVISDEVIKWSEAFLESRQPVLIFVTEKDGDFFVYVQKPKMRSLHKYKLEQQELCNPLSFTAYIKKQIITLLCLYSSDSVYKVLIPLQQSSEEEEQTLSKSLLLNLSISGSVLKGTSFVVLDKDHVAVLGSLAASGEESKECLTIWNTKFQTLQASKELPLGTSGQLWCYGEKFFFTHGKVLTVVIYKCETSSLAAAVGKLKDSQTSDLSSFVNWNTLGDEELLVSLQSQQSVALKSESKMTLRSKKSTVANIQPDTSTVGQFLLSIKDASTAAVEDQLRQLLSKAQMPDFQAAIGCIISALINRCKTDPKFYPRNFLVQMIQKGELSYSLCPDLMAVALEKKDVHLLQICLQRFPDIPEEITYACLKVFLSISDDYLERTDVNLESVISYIDIEPNNKEVKTEVVENGFSTELEEDGCDVTGMKETHMMDSVEFCPVGPQKAALLNAVLHSAYSETFLLPHLKDLPAQQAVLFLRYLHYLYVKCSEKINTTLPGILSPTISQIMDWMCLLLDAHFTVMVMLPEAKGLLSSMHRFVRAQVRLYSELNKIEGSLQELQRIKCQKHSQAYSIEVLELI", "length": 723, "header": "tr|A0A8V1AN63-1|A0A8V1AN63_CHICK Isoform 1 of Nucleolar protein 11 OS=Gallus gallus OX=9031 GN=NOL11 PE=1 SV=1 CANONICAL=A0A8V1AN63-1" }, "locus": { "chromosome": "18", "start_pos": 7691283, "end_pos": 7680405, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070917.1", "url": "https://www.ensembl.org/id/ENSGALT00010070917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043608.1", "url": "https://www.ensembl.org/id/ENSGALP00010043608.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417423", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1A9-1", "protein_name": "Nucleolar protein 11", "gene_name": "Nol11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALEEEFTLSTGVLGAGPEGFLGVEPSDKADQFLVTDRGRTVVLYKVSDQKPLGSWSVKQGQTITCPAVCNFQTGEYIMVHDHKVLRIWNNEDVNLDKVFKATLSAEVHRIHSVQRTEPLVLFRRGAARGLEALLAEPQQNIEAVIPDEEVIEWSEVFMLFKQPVLIFITENHGSYVAYVQLCKSHSLSKYILLLGKEEKSAKPNFTARVDGKFISLVSLGSDGCVYETLVPIYSSDTENNQRLVRALMLKTVVSGSARNGSALTILDQDHIAVLGPPLPASKECLSIWNIKFQTLQTSKELPQGTSGQLWYHGEILFMRHGKSLTVIPYKCEASSLASALGKLKHTQESGSHSVPHFVNWETCSEYELGSYSAKQTRTLRKKTETNLHPEVPGVKELLSIIKKDSEKHIEVELRKFLAKSTPDFHTIIGDIVSGLLGRCKVEPSFYPRNCLMQLIQTHVLSYSLCPDLMEIALEHTDVQMLQLCLQQFPDIPESTTCACLKLFLSIGDDCLRDSNVSMESVFDYGDTTQDEKKEMEEQTEIVQNGFGPEDGGCSKDSQQLNKKPGDTAQEPISFPVTLCPVAPKRAALLRNAVLHSAYSEPFLLPHLKDIPAKHITLFLQYLYFLYLKCTGSATMTLPGVSPPTVSQIMDWICLLLDANFTVVLMIPEAKRLLLNLYNFVKSQISIYSELNKIEVSFRELQRLNQEKSSRGLYSIEVLELF", "length": 723 }, "evidence": [ { "id": "A0A8V1AN63", "url": "https://omabrowser.org/oma/group/A0A8V1AN63/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3MHH2-1", "protein_name": "Nucleolar protein 11", "gene_name": "NOL11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADLEEGFALTAVPLGSGPDGPLGVEQSGKTDQFLVTDSGRTVILYKVSDQKPLGSWSVKQGQIITCPAVCNFQTGEYIVVHDNKVLRIWNNEDVNLDKVFKATLSAEVYRIHSIQGTEPLVLFKEGAVRGLEALLAEPQQKIETVISDEEVIKWTKFFMVFRHPVLIFITEKHGNYFVYVQKFNSRILSKYTLLLGQEEKCVIQSFSTSVGRKFISLMSLSSDGCVYETLIPIHPSEPEKNQRLVQSQLLKSVVSGSARNGVALAILDQDHIAVLGAPLPASKECLSVWNTKFQTLQTSKELPQGTSGQLWYYGENLFMLHGKFLTVVPFKCEVSSLAGALGKLKHSQDPGIHATPHFVNWETSQGCGLGSQNSEQSKRILRRRKVEVSVQPEVPASTQLLATIQKDSEKHIEVELRKFLATKRTPDFHTIIGDVIIGLLGRCKAEPSFYPCNCLMQLVQTHVLSYSLCPGLMEFALEKTDVQILQLCLQQFPDIPESVTCACLKVFLSIGDDTLQDTDINMESVSDYMDPVQDGEMEEQTAFLQNGFSPEEDNCDSCAQKLKEKPQAAADESTSCPVTPKRAALLNAVLHSAYSETFLLPHLKDIPAQHSTLFLQYLYFLYLKCSENATMTLPGTHPPTLSQIMDWICLLLDANFTVVVMIPEAKRLLLSLYKFVKSQISICSELNKIEVSFRELQKLNQEKNNRELYSIEVLELF", "length": 718 }, "evidence": [ { "id": "A0A8V1AN63", "url": "https://omabrowser.org/oma/group/A0A8V1AN63/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BJW5-1", "protein_name": "Nucleolar protein 11", "gene_name": "Nol11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLEEEFTLSTGVLGAGPEGFLGVEQTDKADQFLVTDSGRTVVLYKVSDQKPLGSWSVKQGQSITCPAVCNFQTGEYIMVHDHKVLRIWNNDDVNVDKVFKATLSAEVHRIHSVQRTEPLVLFRGGAARGLEALLVEPQQNIESVIPDEEVIVWSEVFMLFKQPVLIFITENHGHYYAYVRLCKSHSLSKYTLLLEKEEKSVKPNFTARVDGKFISLVSLSSDGCIYETLIPIYSSDTEQNQRLVRALMLKSVVSGGVRNGVALTILDQDHIAVLGPPLSASKECLSIWNIKFQTLQTSKELPQGTSGQLWYHGEVLFMLHGKSLTVIPYKCEESSLAGALGKLKHTQESGTHSVPHFVNWETCSGYELGSSGAEQSRTLRRKKVETNLQPEVPGFKQLLSIIKKDSEKHIEVELRKFLAKSTPAFHTIIGDLVAGLVGRCKAEPSFYPRNCLTQLIQTHVLSYSLCPDLMEIALEHTDVQMLQLCLQQFPDIPESTTCACLKLFLSVGDDCLRDSNINMESVFDYSDSTQDEKKEMEEQIEIVQNGFGPEDGNCSEDSQQLNDKPADTAHEPGSFPVTSCPVAPKRAALLNAVLHSAYSEPFLLPHLKDIPAKHVTLFLQYLYFLYLKCTGSATMTLPGVNPPTVSQIMDWICLLLDANFTVLLMIPEAKRLLLILYNFVKSQISIYSELNKIAVSFRELQRLNREKSSRGLYSIEVLELF", "length": 723 }, "evidence": [ { "id": "A0A8V1AN63", "url": "https://omabrowser.org/oma/group/A0A8V1AN63/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8H0-1", "protein_name": "Nucleolar protein 11", "gene_name": "NOL11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALEEEFTLSSVVLSAGPEGLLGVEQSDKTDQFLVTDSGRTVILYKVSDQKPLGSWSVKQGQIITCPAVCNFQTGEYVVVHDNKVLRIWNNEDVNLDKVFKATLSAEVYRILSVQGTEPLVLFKEGAVRGLEALLADPQQKIETVISDEEVIKWTKFFVVFRHPVLIFITEKHGNYFAYVQMFNSRILTKYTLLLGQDENSVIKSFTASVDRKFISLMSLSSDGCIYETLIPIRPADPEKNQSLVKSLLLKAVVSGNARNGVALTALDQDHVAVLGSPLAASKECLSVWNIKFQTLQTSKELPQGTSGQLWYYGEHLFMLHGKSLTVIPYKCEVSSLAGALGKLKHSQDPGTHVVSHFVNWETPQGCGLGFQNSEQSRRILRRRKIEVSLQPEVPPSKQLLSTIMKDSEKHIEVEVRKFLALKQTPDFHTVIGDTVTGLLERCKAEPSFYPRNCLMQLIQTHVLSYSLCPDLMEIALKKKDVQLLQLCLQQFPDIPESVTCACLKIFLSIGDDSLQETDVNMESVFDYSINSVHDEKMEEQTEILQNGFNPEEDKCNNCDQELNKKPQDETKESTSCPVVQKRAALLNAILHSAYSETFLLPHLKDIPAQHITLFLKYLYFLYLKCSENATMTLPGIHPPTLNQIMDWICLLLDANFTVVVMMPEAKRLLINLYKLVKSQISVYSELNKIEVSFRELQKLNQEKNNRGLYSIEVLELF", "length": 719 }, "evidence": [ { "id": "A0A8V1AN63", "url": "https://omabrowser.org/oma/group/A0A8V1AN63/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VW10-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG9300", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKFLSYYNLFPIPDPKEFLGLAADRENGNVVTTLARNVVVVLNISTQKQLLSWSLPEKLSSKVIYDPSSQKYVGVFGNHALRLWDVDTSDVSKCKKLKFQKSIAHVVATEQEALILYSDGECQTLSQALASRKDQKEDTAEQLALAASKVISKPTVHALAQGQQVLTYFEETKATGEMQLIRLSLDTADRRKYLIKREEVRLTGYAVVEGDADPQLLTIWSDKRIFMLNLAEATSERSPGQFVSMLAELNVESKLSVHGVSRNFAAIYGANYGQEGASLLVYNTQFKVVNAKQYFKVYLDFSRLWAGNEHILLAMGHNIAAVRYRMNREVLVDMLGSQFSDTHLSPIELDHINEEEYLESLIKFDGSTKPLNYRAVKSQLNKQMPNLDYQKADGRELAYDPPEVVDQEIDEIIKQHVHGEATICENGLEDVSVTLMTNFFDKGPNNTAVQALVRQLERSGAGEEEIIERILTLFIKTDNTEHVLMCLRRYSNISERMLAWSLRYALDKCKPRHAINGDSNAVPTAKSYSNKELLNAVLACRFDATGIEEHLRYRLELSHVQHLMSHLFDLVNDPNVQLEERPSLNCSPIQTEVQAIQWFGCILTSHFTLLIISKDEALLETLSEWATFLSFYEESLFDLANLLPLLTNIVEKRQVKPMYSTNWYGIEEVVLY", "length": 673 }, "evidence": [ { "id": "A0A8V1AN63", "url": "https://omabrowser.org/oma/group/A0A8V1AN63/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" } ], "pmid": "" }, { "name": "t-UTP complex", "id": "GO:0034455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034455", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" } ], "pmid": "" }, { "name": "positive regulation of transcription of nucleolar large rRNA by RNA polymerase I", "id": "GO:1901838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901838", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" }, { "id": "PF20998", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20998" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 11 C-terminal", "eco_id": "ECO_0000259", "start_pos": 409, "end_pos": 722, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1AN63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AN63" }, { "id": "PF08168", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08168" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 11 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 335, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 }, { "start_pos": 637, "end_pos": 639 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANA3-1", "uniprot_ac": "A0A8V1ANA3", "uniprot_id": "A0A8V1ANA3_CHICK", "mass": { "chemical_mass": 26742.0, "monoisotopic_mass": 26742.0 }, "refseq": { "ac": "XP_040505449", "name": "uncharacterized protein LOC422090 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505449" }, "gene_names": [ { "name": "LOC422090", "type": "recommended", "evidence": [ { "id": "A0A8V1ANA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA3" } ] }, { "name": "LOC422090", "type": "synonym", "evidence": [ { "id": "XP_040505449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505449" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ANA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC422090 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040505449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505449" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505449" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC422090", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA3", "locus": {} } ], "crossref": [ { "id": "A0A8V1ANA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "422090", "url": "https://www.ncbi.nlm.nih.gov/gene/422090", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MTCEDRR", "url": "https://omabrowser.org/oma/group/MTCEDRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANA3", "url": "https://www.orthodb.org/?gene=A0A8V1ANA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF02393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505449", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ANA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVESRPLKRSLRTGTLYNTKKAKLEFGVLGAIRNTRKAQWAPRQAVKQPNSQLQRSASCFCTAHSLQEIRECVCKFRGTMLGFEKQPQFCLRVGGLEGSFYEGQKELREYCEALYLPQPTSMEVVGTVDDVPCLATGQQLVILVAEGGEVYAYEEETLHKVAKSMQEFMEIGLQHLGKEVYHCGEWIESLDEEERDKDPTIWQLRQSAQHFLEAGKDEFHHLLDLLENKPVVAC", "length": 235, "header": "tr|A0A8V1ANA3-1|A0A8V1ANA3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC422090 PE=1 SV=1 CANONICAL=A0A8V1ANA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA3/entry#A0A8V1ANA3-1", "sequence": { "sequence": "MSVESRPLKRSLRTGTLYNTKKAKLEFGVLGAIRNTRKAQWAPRQAVKQPNSQLQRSASCFCTAHSLQEIRECVCKFRGTMLGFEKQPQFCLRVGGLEGSFYEGQKELREYCEALYLPQPTSMEVVGTVDDVPCLATGQQLVILVAEGGEVYAYEEETLHKVAKSMQEFMEIGLQHLGKEVYHCGEWIESLDEEERDKDPTIWQLRQSAQHFLEAGKDEFHHLLDLLENKPVVAC", "length": 235, "header": "tr|A0A8V1ANA3-1|A0A8V1ANA3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC422090 PE=1 SV=1 CANONICAL=A0A8V1ANA3-1" }, "locus": { "chromosome": "18", "start_pos": 10509038, "end_pos": 10507826, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010070969.1", "url": "https://www.ensembl.org/id/ENSGALT00010070969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043660.1", "url": "https://www.ensembl.org/id/ENSGALP00010043660.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANA9-1", "uniprot_ac": "A0A8V1ANA9", "uniprot_id": "A0A8V1ANA9_CHICK", "mass": { "chemical_mass": 38611.0, "monoisotopic_mass": 38611.0 }, "refseq": {}, "gene_names": [ { "name": "DHRS13", "type": "recommended", "evidence": [ { "id": "A0A8V1ANA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9" } ] } ], "protein_names": [ { "name": "Dehydrogenase/reductase 13", "type": "synonym", "evidence": [ { "id": "A0A8V1ANA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DHRS13", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9", "locus": { "chromosome": "19", "start_pos": 6364061, "end_pos": 6367043, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029675", "url": "https://www.ensembl.org/id/ENSGALG00010029675" } ] } } ], "crossref": [ { "id": "A0A8V1ANA9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANA9", "url": "https://www.orthodb.org/?gene=A0A8V1ANA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1ANA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWWLLVVGLLLCVLLRFALRSSTPPFALHALHGRTAVVTGEHGGSAWRCPTAGCSLLSVVLCSAGGSSGIGEAVARELARCGARVVLATRDALRGEEAAWRIRRPQDQLLPPPPPPQDTGNPEVLFMPLDLSSLHSVHAFATAFLQQEPHLHLLINNAGVSAGGTTEDGFSLPFQVNHLGHFLLTQLLLQRLQSSAPSRVVIVASSAHCAGRLRMAELGCPPPGPFAAFQDYCDSKLANVLHARQLAARLQGTGVTAYAVHPGFVNTRLFRHAPLWLQLLWTPLSRFCFRSAAEGARTVLFCATQDGLEPFSGCYFADCRPLQPWAQGRDDAAARELWDRSERLLGLQPSLCTPVE", "length": 357, "header": "tr|A0A8V1ANA9-1|A0A8V1ANA9_CHICK Isoform 1 of Dehydrogenase/reductase 13 OS=Gallus gallus OX=9031 GN=DHRS13 PE=1 SV=1 CANONICAL=A0A8V1ANA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9/entry#A0A8V1ANA9-1", "sequence": { "sequence": "MGWWLLVVGLLLCVLLRFALRSSTPPFALHALHGRTAVVTGEHGGSAWRCPTAGCSLLSVVLCSAGGSSGIGEAVARELARCGARVVLATRDALRGEEAAWRIRRPQDQLLPPPPPPQDTGNPEVLFMPLDLSSLHSVHAFATAFLQQEPHLHLLINNAGVSAGGTTEDGFSLPFQVNHLGHFLLTQLLLQRLQSSAPSRVVIVASSAHCAGRLRMAELGCPPPGPFAAFQDYCDSKLANVLHARQLAARLQGTGVTAYAVHPGFVNTRLFRHAPLWLQLLWTPLSRFCFRSAAEGARTVLFCATQDGLEPFSGCYFADCRPLQPWAQGRDDAAARELWDRSERLLGLQPSLCTPVE", "length": 357, "header": "tr|A0A8V1ANA9-1|A0A8V1ANA9_CHICK Isoform 1 of Dehydrogenase/reductase 13 OS=Gallus gallus OX=9031 GN=DHRS13 PE=1 SV=1 CANONICAL=A0A8V1ANA9-1" }, "locus": { "chromosome": "19", "start_pos": 6366844, "end_pos": 6364795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071774.1", "url": "https://www.ensembl.org/id/ENSGALT00010071774.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044464.1", "url": "https://www.ensembl.org/id/ENSGALP00010044464.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANC3-1", "uniprot_ac": "A0A8V1ANC3", "uniprot_id": "A0A8V1ANC3_CHICK", "mass": { "chemical_mass": 53338.0, "monoisotopic_mass": 53338.0 }, "refseq": { "ac": "XP_024997563", "name": "monocarboxylate transporter 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997563" }, "gene_names": [ { "name": "SLC16A5", "type": "recommended", "evidence": [ { "id": "A0A8V1ANC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3" } ] }, { "name": "SLC16A5", "type": "synonym", "evidence": [ { "id": "XP_024997563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997563" } ] } ], "protein_names": [ { "name": "Solute carrier family 16 member 5", "type": "synonym", "evidence": [ { "id": "A0A8V1ANC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3/entry#names_and_taxonomy" } ] }, { "name": "monocarboxylate transporter 6", "type": "synonym", "evidence": [ { "id": "XP_024997563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024997563.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024997563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC16A5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3", "locus": { "chromosome": "18", "start_pos": 11283381, "end_pos": 11274378, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029687", "url": "https://www.ensembl.org/id/ENSGALG00010029687" } ] } } ], "crossref": [ { "id": "A0A8V1ANC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "422117", "url": "https://www.ncbi.nlm.nih.gov/gene/422117", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TWGAYQT", "url": "https://omabrowser.org/oma/group/TWGAYQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANC3", "url": "https://www.orthodb.org/?gene=A0A8V1ANC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024997563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024997563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ANC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQGGAAARGAAKVQDQGWAWMVLVAAVVLQGLTLGFPSCIGVFFTDLQHEFQATNSETSWFPSIMVAVLHAGGPLCSILVKRFGCRFAVMVGGLLSSVGMVSSSFCKSLSQLYLTAGLVTGLGSCFSFQAGVTALGYYFVRWRTLANAMASTGVSIGLTLWPLLSQYLLDEMGWRNTFLIFGGILLNCCVCGAVMRPVKFALGSLLQFPSPEEEPGRRAEEVQLSNGASSPHLKLQEQTRKIACFQALQKYLAFDIFCQNKGYQIYTIGVTWMMMGFVLPHVYLVPYAIQNGVDERRAALLISIIGFINIFIRPLTGLLSGQTIFTGRRIYLYSLAVLLCGLSNFICVISAKFSMLIFYCVILSIAMSGIGALTFQVLMDVVEMDRFSSALGLFTILESITLLIGPPLTGLLVDITSDFRYVFYTSSFFLISASLFMVLSFCALEKKNKLKDTSKVPPDRSTIYNETPNESQSESQPTLAVVHITSI", "length": 488, "header": "tr|A0A8V1ANC3-1|A0A8V1ANC3_CHICK Isoform 1 of Solute carrier family 16 member 5 OS=Gallus gallus OX=9031 GN=SLC16A5 PE=4 SV=1 CANONICAL=A0A8V1ANC3-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3/entry#A0A8V1ANC3-1", "sequence": { "sequence": "MAQGGAAARGAAKVQDQGWAWMVLVAAVVLQGLTLGFPSCIGVFFTDLQHEFQATNSETSWFPSIMVAVLHAGGPLCSILVKRFGCRFAVMVGGLLSSVGMVSSSFCKSLSQLYLTAGLVTGLGSCFSFQAGVTALGYYFVRWRTLANAMASTGVSIGLTLWPLLSQYLLDEMGWRNTFLIFGGILLNCCVCGAVMRPVKFALGSLLQFPSPEEEPGRRAEEVQLSNGASSPHLKLQEQTRKIACFQALQKYLAFDIFCQNKGYQIYTIGVTWMMMGFVLPHVYLVPYAIQNGVDERRAALLISIIGFINIFIRPLTGLLSGQTIFTGRRIYLYSLAVLLCGLSNFICVISAKFSMLIFYCVILSIAMSGIGALTFQVLMDVVEMDRFSSALGLFTILESITLLIGPPLTGLLVDITSDFRYVFYTSSFFLISASLFMVLSFCALEKKNKLKDTSKVPPDRSTIYNETPNESQSESQPTLAVVHITSI", "length": 488, "header": "tr|A0A8V1ANC3-1|A0A8V1ANC3_CHICK Isoform 1 of Solute carrier family 16 member 5 OS=Gallus gallus OX=9031 GN=SLC16A5 PE=4 SV=1 CANONICAL=A0A8V1ANC3-1" }, "locus": { "chromosome": "18", "start_pos": 11282651, "end_pos": 11275416, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071799.1", "url": "https://www.ensembl.org/id/ENSGALT00010071799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044489.1", "url": "https://www.ensembl.org/id/ENSGALP00010044489.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4A3B5-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQALEQADGRWAWVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNSETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVATNVDPEPKEDLLLPPKTPTRSCLATCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAGMLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLLDTTNNFNYVFYMSSGLLISASLFMGVGFYVAEKKLKQDRQAKMEDATSEITSKHSLTSEDKDSAKKQPYPENIYVTSV", "length": 466 }, "evidence": [ { "id": "A0A8V1ANC3", "url": "https://omabrowser.org/oma/group/A0A8V1ANC3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FB53-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPQQPSSMEEQSGELCEPESEELEKQGPGPPSNANAPDSYDAPDGGWGWVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEATNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPIRPRKPRKTNEINNSPKTSDKKGCMLGICQSLASSLRQQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRPPVGVLFSLPWFKGRHIYVFSAALLINGLSNSICCISASFPVLLVYVLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSVPIDGDKTNKPSSETENTTCV", "length": 506 }, "evidence": [ { "id": "A0A8V1ANC3", "url": "https://omabrowser.org/oma/group/A0A8V1ANC3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3X6A0-1", "protein_name": "Solute carrier family 16 member 5", "gene_name": "SLC16A5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQALERSEGCWAWVVLLASVVTQGLTLGFPTCIGIFFTELQREFQASNSETSWFPSILTAMLHAGGPLCSILVGRFGCRATMMLGGVLASLGMVAGSFCRTLGQLYLTAGFITGLGMCFSFQSSITVLGLYFTRWQVLANALASAGVSLGITLWPLLSRYLLEDLGWRGTFLIFGGVLLHCCVCGAVVRPVPASVTPEAREGLPSPSKRPSRGCPAACGRAIRRHLAFDVLRDNVGYRVYTLGVVWMILGFPLPHVFLVPYAIRHGMDEQKAALLISVIGFSNIFLRPMAGLVAGRREFAGHRKYLFSLAALLNGLTNLVCVASADFRVLVGYCLAYSVSMSGIGALLFQVLMDIVPMDRFSSALGLFTVLESISILISPPLAGLLLDTTDDFSYVFYMSSFFLISAALFMGGSFCVLGKKERQGPWAEAKGAVPEAAPEQGLATEDMDGPEKRLRVEIMYVTSV", "length": 466 }, "evidence": [ { "id": "A0A8V1ANC3", "url": "https://omabrowser.org/oma/group/A0A8V1ANC3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O15375-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "SLC16A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT", "length": 505 }, "evidence": [ { "id": "A0A8V1ANC3", "url": "https://omabrowser.org/oma/group/A0A8V1ANC3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC3" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 446, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 466, "end_pos": 468 }, { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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[], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatid development", "id": "GO:0007286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANC9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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"gene_names": [], "protein_names": [ { "name": "Esterase OVCA2", "type": "recommended", "evidence": [ { "id": "A0A8V1ANK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK8/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.1", "type": "synonym", "evidence": [ { "id": "A0A8V1ANK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK8/entry#names_and_taxonomy" } ] }, { "name": "OVCA2 serine hydrolase domain-containing protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ANK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Exhibits ester hydrolase activity with a strong preference for long-chain alkyl ester substrates and high selectivity against a variety of short, branched, and substituted esters. Is able to hydrolyze ester bonds within a wide range of p-nitrophenyl derivatives (C2-C14) in vitro, with a strong preference toward substrates of >8 carbons.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK8#function" }, { "database": "UniProtKB", "id": "ARBA00093420", "url": "https://www.uniprot.org/uniprotkb/ARBA00093420#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANK8", "locus": {} } ], "crossref": [ { "id": "IPR005645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005645", "database": "InterPro", 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"lysosomal protein catabolic process", "id": "GO:1905146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANM6-1", "uniprot_ac": "A0A8V1ANM6", "uniprot_id": "A0A8V1ANM6_CHICK", "mass": { "chemical_mass": 50977.0, "monoisotopic_mass": 50977.0 }, "refseq": { "ac": "XP_415852", "name": "sedoheptulokinase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415852" }, "gene_names": [ { "name": "SHPK", "type": "recommended", "evidence": [ { "id": "A0A8V1ANM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ] }, { "name": "SHPK", "type": "synonym", "evidence": [ { "id": "XP_415852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415852" } ] } ], "protein_names": [ { "name": "Sedoheptulokinase", "type": "recommended", "evidence": [ { "id": "A0A8V1ANM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.14", "type": "synonym", "evidence": [ { "id": "A0A8V1ANM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6/entry#names_and_taxonomy" } ] }, { "name": "Carbohydrate kinase-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V1ANM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6/entry#names_and_taxonomy" } ] }, { "name": "sedoheptulokinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415852" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415852.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415852" } ] }, { "annotation": "Acts as a modulator of macrophage activation through control of glucose metabolism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6#function" }, { "database": "UniProtKB", "id": "ARBA00057196", "url": "https://www.uniprot.org/uniprotkb/ARBA00057196#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHPK", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6", "locus": { "chromosome": "19", "start_pos": 7145537, "end_pos": 7137050, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029745", "url": "https://www.ensembl.org/id/ENSGALG00010029745" } ] } } ], "crossref": [ { "id": "A0A8V1ANM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417607", "url": "https://www.ncbi.nlm.nih.gov/gene/417607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TWQDTRC", "url": "https://omabrowser.org/oma/group/TWQDTRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANM6", "url": "https://www.orthodb.org/?gene=A0A8V1ANM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-71336", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415852", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23844", "url": "https://www.rhea-db.org/rhea/23844", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDGPDSVCMLGIDLGTTSVKAALVVGTERGQVVAESCSRETQAYTSSVEAGLQGMEQDSRRIIRALNECLAALPQQQLQRVSHIGISGQMHGIVFWKRDQGCKWAEGGTGPIFEPEEVSHLVTWQDGRCSPAFLSSLPLPQSHISLATGFGCATIYWYLKQSPDFLKSYDAAGTIHDYVVAMLCDLKKPLMSVQNAASWGYFNSRNKSWNTDILKKSGFPVHLLPEVGDPGSIAGRTICAWHGIPKGTKVGIALGDFQCSVYSCLTERTDAVLNISTSAQLTISMPSGFQPPETPDPSSAVTYFPYFDGDYLAVAASLNGGNVLATFVDMVARWTEELGFQIQESAIYAKIIKAALDQNDSHLSVRPTLFGERHIPDQLASVTSIAASELSLGHVTRAVCRGVIENLCSMLPVQRLMETGVRRILGSGSALARNEVLRQEVERILPFPVVYGKDVDAAVGAAMVMFHRK", "length": 470, "header": "tr|A0A8V1ANM6-1|A0A8V1ANM6_CHICK Isoform 1 of Sedoheptulokinase OS=Gallus gallus OX=9031 GN=SHPK PE=1 SV=1 CANONICAL=A0A8V1ANM6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6/entry#A0A8V1ANM6-1", "sequence": { "sequence": "MEDGPDSVCMLGIDLGTTSVKAALVVGTERGQVVAESCSRETQAYTSSVEAGLQGMEQDSRRIIRALNECLAALPQQQLQRVSHIGISGQMHGIVFWKRDQGCKWAEGGTGPIFEPEEVSHLVTWQDGRCSPAFLSSLPLPQSHISLATGFGCATIYWYLKQSPDFLKSYDAAGTIHDYVVAMLCDLKKPLMSVQNAASWGYFNSRNKSWNTDILKKSGFPVHLLPEVGDPGSIAGRTICAWHGIPKGTKVGIALGDFQCSVYSCLTERTDAVLNISTSAQLTISMPSGFQPPETPDPSSAVTYFPYFDGDYLAVAASLNGGNVLATFVDMVARWTEELGFQIQESAIYAKIIKAALDQNDSHLSVRPTLFGERHIPDQLASVTSIAASELSLGHVTRAVCRGVIENLCSMLPVQRLMETGVRRILGSGSALARNEVLRQEVERILPFPVVYGKDVDAAVGAAMVMFHRK", "length": 470, "header": "tr|A0A8V1ANM6-1|A0A8V1ANM6_CHICK Isoform 1 of Sedoheptulokinase OS=Gallus gallus OX=9031 GN=SHPK PE=1 SV=1 CANONICAL=A0A8V1ANM6-1" }, "locus": { "chromosome": "19", "start_pos": 7145515, "end_pos": 7137702, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071957.1", "url": "https://www.ensembl.org/id/ENSGALT00010071957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044647.1", "url": "https://www.ensembl.org/id/ENSGALP00010044647.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-71336", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71336", "resource": "Reactome", "description": "Pentose phosphate pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3S5ZPP1-1", "protein_name": "Sedoheptulokinase", "gene_name": "SHPK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAARSVTLGIDLGTTSVKAALVEAALGDPSGFVVLASCARAAQAETAAQSAAAGPQGQEQDVKRIIQALHECLAALPRQQLRKVCGIGVSGQMHGVMFWKTGQGCAWTEGGAAPVFEPRAVSHLVTWQDGRCSSEFLASLPQPESHLSVATGFGCATIFWLLKNSPEFLKSYDTAGTIHDYVVAMLCGLARPLMSDQNAASWGYFNTRSQSWNLEILRAAGFPVQLLPDVAEPGSVAGRTSQAWFEIPKGTQVGVALGDLQASVYSCMAQKTDAVLNISTSVQLVASMPSGFQPPETPDPAAPVAYFPYFDRTYLAVAASLNGGNVLATFVHMLVQWMADLGLQVEESMVYSCMIQAAAQQRDTCLTITPTVLGERHLPDQLASVTGISSSDLSLGHVTRALCRGIVQNLHSMLPFRQLREWGVERVIGSGSALSRNEVLKQEVQRAFPLPVSYGQDVDAAVGAALVMLQRSLSQQKS", "length": 478 }, "evidence": [ { "id": "A0A8V1ANM6", "url": "https://omabrowser.org/oma/group/A0A8V1ANM6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RLI9-1", "protein_name": "Sedoheptulokinase", "gene_name": "SHPK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAARSVTLGIDLGTTSVKAALVEASPGDPSGFVVLASCARAAQAETAAQSAAAGSQGQEQDVRRIVQALHACLAALPQQHLRKVCGIGVSGQMHGVMFWKTGQGCEWTEGGAAPVFEPRAVSHLVTWQDGRCSSKFLASLPQPESHLSVATGFGCATIFWLLKNSPEFLKSYDAAGTIHDYVVAMLCGLTRPLMSDQNAASWGYFNTGSQSWNLEILKTAGFPVHLLPDVAEPGSIAGRTSRTWFEIPKGTPVGVALGDLQASVYSCMARRTDAVLNISTSVQLVASMPPVFQPVQTPDPTAPVAYFPYFNRTYLAVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAAQQRDTCLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPFQQLQAWGVERVIGSGSALSRNEVLKQEVQRAFPLPVAYGQDVDAAVGAALVMLQRNLNQQES", "length": 478 }, "evidence": [ { "id": "A0A8V1ANM6", "url": "https://omabrowser.org/oma/group/A0A8V1ANM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D5J6-1", "protein_name": "Sedoheptulokinase", "gene_name": "Shpk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRPVTLGIDLGTTSVKAALLEAAPSLPSGFVVLASCARAARAETESAVAGPQGREQDVTRIIQALNECLDALPRQQLQRVRGIGVSGQMHGILFWKAGQGCEWMEGGPAFVFEPRAVSHLVTWQDGRCNSSFLASLPKPDSHLSVATGFGCATIFWLLKNSPEFLKSYDAAGTIQDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNLDTLEKAGFPIHLLPDIAEPGSMAGRTSHTWFEIPKGTQVGIALGDLQASVYSCMGQRTDAVLNISTSVQLAASMPVGFQPLQTPDPAAPVAFFPYFDRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAAQQKDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPFQQLKEWGVARVVGSGSALSRNEVLKQEVQRAFPFPVCFGQDVDAAFGAALVMLQRDLSQKEP", "length": 476 }, "evidence": [ { "id": "A0A8V1ANM6", "url": "https://omabrowser.org/oma/group/A0A8V1ANM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHJ6-1", "protein_name": "Sedoheptulokinase", "gene_name": "SHPK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHDYVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQQRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQEWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES", "length": 478 }, "evidence": [ { "id": "A0A8V1ANM6", "url": "https://omabrowser.org/oma/group/A0A8V1ANM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sedoheptulokinase activity", "id": "GO:0050277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "pentose-phosphate shunt, non-oxidative branch", "id": "GO:0009052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" }, { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" }, { "name": "cellular response to lipopolysaccharide", "id": "GO:0071222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" }, { "name": "cellular response to interleukin-4", "id": "GO:0071353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" }, { "name": "regulation of macrophage activation", "id": "GO:0043030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" }, { "name": "cellular response to interleukin-13", "id": "GO:0035963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23844", "name": "", "equation": "sedoheptulose + ATP = D-sedoheptulose 7-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ANM6-1" ], "evidence": [ { "id": "23844", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23844" } ] }, { "id": "R-GGA-8959719", "name": "SHPK phosphorylates Sedo to Sedo7P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-8959707" ], "output_participant_list": [], "enzyme_list": [ "A0A8V1ANM6-1" ], "evidence": [ { "id": "R-GGA-8959719", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8959719" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8959707", "participant_name": "Sedo [cytosol]", "crossref": [ { "id": "16802", "database": "ChEBI", "url": "" }, { "id": "C02076", "database": "COMPOUND", "url": "" }, { "id": "ZINC000008579422", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V1ANM6", "gene_name": "SHPK", "activity": [ { "ec_number": "2.7.1.14", "activity": "sedoheptulose + ATP = D-sedoheptulose 7-phosphate + ADP + H(+).", "evidence": [ { "id": "A0A8V1ANM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ] }, { "ec_number": "2.7.1.14", "activity": "", "evidence": [ { "id": "A0A8V1ANM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANM6" }, { "id": "PF00370", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate kinase FGGY N-terminal", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 101, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.14", "ec_name": "sedoheptulose + ATP = D-sedoheptulose 7-phosphate + ADP + H(+).", "evidence": [ { "id": "2.7.1.14", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.14" }, { "id": "2.7.1.14", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.14" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 360, "end_pos": 362 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANN7-1", "uniprot_ac": "A0A8V1ANN7", "uniprot_id": "A0A8V1ANN7_CHICK", "mass": { "chemical_mass": 71859.0, "monoisotopic_mass": 71859.0 }, "refseq": { "ac": "XP_015151545", "name": "forkhead box protein N1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151545" }, "gene_names": [ { "name": "FOXN1", "type": "recommended", "evidence": [ { "id": "A0A8V1ANN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ] }, { "name": "FOXN1", "type": "synonym", "evidence": [ { "id": "XP_015151545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151545" } ] } ], "protein_names": [ { "name": "Forkhead box N1", "type": "synonym", "evidence": [ { "id": "A0A8V1ANN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein N1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015151545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151545" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151545.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151545" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FOXN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7", "locus": { "chromosome": "19", "start_pos": 6199320, "end_pos": 6170568, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029415", "url": "https://www.ensembl.org/id/ENSGALG00010029415" } ] } } ], "crossref": [ { "id": "A0A8V1ANN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417570", "url": "https://www.ncbi.nlm.nih.gov/gene/417570", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049624", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049624", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46721:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46721:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSLLQDQSNIKFSSSDTLERDQQEDLMKTPGDSVSPVQQTDNPSYNCQPYESDSRTERKSSESSHSPSPASPAQDQLLGRYPPSQGIHCGKNKFQVSFSTEKFRRCSYEENTVGNYDRFLKSSRNPFHPYKRQISEDVFQEAQQTLPAEGPSFKNTRSIEGFEGLPGSTGPDESESFPAHLPNISSEQPWCNSLQYSTTGQDHSSQVMDSDLKLRTSPLEGQPGLYCYQPQVQQMYCSSHPFHQYPSGGSYPVTYITSSHYPYQRIAPQSTQESQQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGNSSRKGCLWALNPAKIDKMQEELQKWKRKDPVAVRKSMAKPEELDTLIGDKGEKLRSSIMSCGPNGVAGAPLSRQMAVQPHSLGEPSLSSIPQPLHPIHTSSGALHAKNALPNLLGGQQTGCYTAPQGFPPISSALMPQTPDHQTMFPSGEAPNELRGQPSITQDSPLPAQTPPSCGVKVMTEHCTARTVPDPLLQEGDLSNDIDALNPSLTDFDLQGNLWEELKDDSLAVDPLVLISSSPTSSQCFPSHCQMENSNAVAIPNGTPHSNLPDLQLTTLYSAFMELDTVSPAYLGNPGSKPIALM", "length": 652, "header": "tr|A0A8V1ANN7-1|A0A8V1ANN7_CHICK Isoform 1 of Forkhead box N1 OS=Gallus gallus OX=9031 GN=FOXN1 PE=4 SV=1 CANONICAL=A0A8V1ANN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7/entry#A0A8V1ANN7-1", "sequence": { "sequence": "MVSLLQDQSNIKFSSSDTLERDQQEDLMKTPGDSVSPVQQTDNPSYNCQPYESDSRTERKSSESSHSPSPASPAQDQLLGRYPPSQGIHCGKNKFQVSFSTEKFRRCSYEENTVGNYDRFLKSSRNPFHPYKRQISEDVFQEAQQTLPAEGPSFKNTRSIEGFEGLPGSTGPDESESFPAHLPNISSEQPWCNSLQYSTTGQDHSSQVMDSDLKLRTSPLEGQPGLYCYQPQVQQMYCSSHPFHQYPSGGSYPVTYITSSHYPYQRIAPQSTQESQQPLFPKPIYSYSILIFMALKNSKTGSLPVSEIYNFMTEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKSGNSSRKGCLWALNPAKIDKMQEELQKWKRKDPVAVRKSMAKPEELDTLIGDKGEKLRSSIMSCGPNGVAGAPLSRQMAVQPHSLGEPSLSSIPQPLHPIHTSSGALHAKNALPNLLGGQQTGCYTAPQGFPPISSALMPQTPDHQTMFPSGEAPNELRGQPSITQDSPLPAQTPPSCGVKVMTEHCTARTVPDPLLQEGDLSNDIDALNPSLTDFDLQGNLWEELKDDSLAVDPLVLISSSPTSSQCFPSHCQMENSNAVAIPNGTPHSNLPDLQLTTLYSAFMELDTVSPAYLGNPGSKPIALM", "length": 652, "header": "tr|A0A8V1ANN7-1|A0A8V1ANN7_CHICK Isoform 1 of Forkhead box N1 OS=Gallus gallus OX=9031 GN=FOXN1 PE=4 SV=1 CANONICAL=A0A8V1ANN7-1" }, "locus": { "chromosome": "19", "start_pos": 6198639, "end_pos": 6185575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071158.1", "url": "https://www.ensembl.org/id/ENSGALT00010071158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043849.1", "url": "https://www.ensembl.org/id/ENSGALP00010043849.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "T cell lineage commitment", "id": "GO:0002360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002360", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell differentiation", "id": "GO:0030858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030858", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "regulation of positive thymic T cell selection", "id": "GO:1902232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "blood vessel morphogenesis", "id": "GO:0048514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "T cell homeostasis", "id": "GO:0043029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "thymus epithelium morphogenesis", "id": "GO:0097536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "lymphoid lineage cell migration into thymus", "id": "GO:0097535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097535", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANN7" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 282, "end_pos": 378, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 611, "end_pos": 613 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANP1-1", "uniprot_ac": "A0A8V1ANP1", "uniprot_id": "A0A8V1ANP1_CHICK", "mass": { "chemical_mass": 186455.0, "monoisotopic_mass": 186455.0 }, "refseq": { "ac": "XP_015135428", "name": "cholesterol transporter ABCA5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135428" }, "gene_names": [ { "name": "ABCA5", "type": "recommended", "evidence": [ { "id": "A0A8V1ANP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ] }, { "name": "ABCA5", "type": "synonym", "evidence": [ { "id": "XP_015135428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135428" } ] } ], "protein_names": [ { "name": "Cholesterol transporter ABCA5", "type": "recommended", "evidence": [ { "id": "A0A8V1ANP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1/entry#names_and_taxonomy" } ] }, { "name": "ATP-binding cassette sub-family A member 5", "type": "synonym", "evidence": [ { "id": "A0A8V1ANP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1/entry#names_and_taxonomy" } ] }, { "name": "cholesterol transporter ABCA5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015135428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135428" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015135428.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135428" } ] }, { "annotation": "Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport. May play a role in the processing of autolysosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1#function" }, { "database": "UniProtKB", "id": "ARBA00057378", "url": "https://www.uniprot.org/uniprotkb/ARBA00057378#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABCA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1", "locus": { "chromosome": "18", "start_pos": 8583787, "end_pos": 8608567, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029418", "url": "https://www.ensembl.org/id/ENSGALG00010029418" } ] } } ], "crossref": [ { "id": "cd03263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417444", "url": "https://www.ncbi.nlm.nih.gov/gene/417444", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417444", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417444", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNPLWPD", "url": "https://omabrowser.org/oma/group/MNPLWPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANP1", "url": "https://www.orthodb.org/?gene=A0A8V1ANP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1369062", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1369062", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015135428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135428", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "39051", "url": "https://www.rhea-db.org/rhea/39051", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPNAPREAGVWRQTKALLFKNCLVKCRTKKSSVQEVLFPLFFLFWLILMSMMHPHRWYDEVPNSNLGVLDPSVLVNLVVGYTPPTRMAREIMRKVAYDNFEDAGLITEEYLSEEDLEKASASKSSNFVGVVFKDAMSYQLRFPDMVAMASVYTESRASCSSMRMSCESITYWTSGFAALQACIDAAIIQLKTNQSVWEQLELTRAMAMEEAAVMEIDNFPRAIILIYLVIAFSPFGYYLAIHIVAEKERKLKEFLKILGLHDTAFWLSWVLLYTSLIFVMSILMAVIATASSLFPQSSAFVIFLLFFLYGISSVFFALMLTPLFKKSKHVGIVEFLATLAFGFVGLNIVLLEDFPKSFVWLFSPLCQCSFLIGIAQVMHLEDYEDGATFSNLNHGPYPLFISLILLVLDSIFYLLAAVYLDQVIPGEFGLRRSSFFFMKPSFWSKRRKNYEELYESSINGNLSCSEMVEPVPSEFQGKEAIRISCVQKTFRKKGETVEALRNLSFDIYEGQITALLGHSGTGKTTLMNILCGLCPPTDGFVSVYGHRVSEIDEMLEVRRIAGVCPQSDIHFDILTVEENLSLFAAIKGIPQNDLIQEVQKVLLDLDMQPIRDNQAKKLSGGQKRRLSVGIAVLGNPKVLLLDEPTAGMDPCSRHIVWNLLKNRKANCVTVFSTHFMDEADILADRKAVISQGMLKCLGSSLFLKSKWGIGYRLSMHIDAYCNTEATTSLIRQHIPAASLIQENTQQLVYTLPLRDMDKFAGLFSDLDTHSHLGVISYGVSMTTLEDVYLKLEVEAEIDQADYSVFSSQQAQEETDMSSQDDMEQSLLMLPEARSAPQSNTALWKKQVSTIAKLHFLSLKRESKCVRVMLLLFLIFLIVQILFFLTHHYIKHSLAPLRLSPELYLLRPGEEHHKYRSRLLLQNSTDSDIDDVVRSLGSMNVLVEMFNGSDYISAAPHSAGLNVYDLESQQNYVFTIVFNSTMVHSLPVLMNIISNLLLRALNVTESIQVWSHPFVQDLPDTVFKLEIYFEAVLLGIIVTGMPPYFAMENAENRKLRAYTQLQIAGLYPSAYWAGQALVDLPLFFSILVLMLGSLFAFHYGIYFYAGKFMAVLFCLIGYVPSVVLFTYVVSFTFKKVQNTKEFWSFIYSVTALLCMVVTEVAFFLDFDTVTTALHCVFCTFVPIYPLIGCLICFIKVSWTGKQKRGEYYDPWDRLLVAVIAPYLQCIVWLFLLRCFELKSGGRTIREDPFFRKCSKRAKSWKLPDAPCNEDEDVRAERLRVKEALSNPNSEEVPAILVSSLHKEYDERREFLLGRRIKKVATKHVSLCIRKGEILGLLGPNGAGKSTLINMLVGEVEPTSGQVLMGGCSPGGNSEEDSIQFVGYCPQTNPLWPDITLQEHFEIYGAIKGMSQADVKQAIKCISSALDFKDHLQKTTKKLGVGLKRKLCFALSMLGSPRVTLLDEPSTGMDPKAKQRMWRAIRAAFKNKERAAILTTHYMEEADAVCDRVAILVAGQLRCIGTVQHLKSKFGRGYFLEMKLKDTADVQQVEYLQRQVLHIFPNANRQESFASILAYKIPREDVQSLSHCFSKLEEVKYAFNIEEYSFSQATLEQVFVELAKEQEEEEGSFGTLNSTLWWDRTQEDRVVF", "length": 1647, "header": "tr|A0A8V1ANP1-1|A0A8V1ANP1_CHICK Isoform 1 of Cholesterol transporter ABCA5 OS=Gallus gallus OX=9031 GN=ABCA5 PE=3 SV=1 CANONICAL=A0A8V1ANP1-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1/entry#A0A8V1ANP1-1", "sequence": { "sequence": "MAPNAPREAGVWRQTKALLFKNCLVKCRTKKSSVQEVLFPLFFLFWLILMSMMHPHRWYDEVPNSNLGVLDPSVLVNLVVGYTPPTRMAREIMRKVAYDNFEDAGLITEEYLSEEDLEKASASKSSNFVGVVFKDAMSYQLRFPDMVAMASVYTESRASCSSMRMSCESITYWTSGFAALQACIDAAIIQLKTNQSVWEQLELTRAMAMEEAAVMEIDNFPRAIILIYLVIAFSPFGYYLAIHIVAEKERKLKEFLKILGLHDTAFWLSWVLLYTSLIFVMSILMAVIATASSLFPQSSAFVIFLLFFLYGISSVFFALMLTPLFKKSKHVGIVEFLATLAFGFVGLNIVLLEDFPKSFVWLFSPLCQCSFLIGIAQVMHLEDYEDGATFSNLNHGPYPLFISLILLVLDSIFYLLAAVYLDQVIPGEFGLRRSSFFFMKPSFWSKRRKNYEELYESSINGNLSCSEMVEPVPSEFQGKEAIRISCVQKTFRKKGETVEALRNLSFDIYEGQITALLGHSGTGKTTLMNILCGLCPPTDGFVSVYGHRVSEIDEMLEVRRIAGVCPQSDIHFDILTVEENLSLFAAIKGIPQNDLIQEVQKVLLDLDMQPIRDNQAKKLSGGQKRRLSVGIAVLGNPKVLLLDEPTAGMDPCSRHIVWNLLKNRKANCVTVFSTHFMDEADILADRKAVISQGMLKCLGSSLFLKSKWGIGYRLSMHIDAYCNTEATTSLIRQHIPAASLIQENTQQLVYTLPLRDMDKFAGLFSDLDTHSHLGVISYGVSMTTLEDVYLKLEVEAEIDQADYSVFSSQQAQEETDMSSQDDMEQSLLMLPEARSAPQSNTALWKKQVSTIAKLHFLSLKRESKCVRVMLLLFLIFLIVQILFFLTHHYIKHSLAPLRLSPELYLLRPGEEHHKYRSRLLLQNSTDSDIDDVVRSLGSMNVLVEMFNGSDYISAAPHSAGLNVYDLESQQNYVFTIVFNSTMVHSLPVLMNIISNLLLRALNVTESIQVWSHPFVQDLPDTVFKLEIYFEAVLLGIIVTGMPPYFAMENAENRKLRAYTQLQIAGLYPSAYWAGQALVDLPLFFSILVLMLGSLFAFHYGIYFYAGKFMAVLFCLIGYVPSVVLFTYVVSFTFKKVQNTKEFWSFIYSVTALLCMVVTEVAFFLDFDTVTTALHCVFCTFVPIYPLIGCLICFIKVSWTGKQKRGEYYDPWDRLLVAVIAPYLQCIVWLFLLRCFELKSGGRTIREDPFFRKCSKRAKSWKLPDAPCNEDEDVRAERLRVKEALSNPNSEEVPAILVSSLHKEYDERREFLLGRRIKKVATKHVSLCIRKGEILGLLGPNGAGKSTLINMLVGEVEPTSGQVLMGGCSPGGNSEEDSIQFVGYCPQTNPLWPDITLQEHFEIYGAIKGMSQADVKQAIKCISSALDFKDHLQKTTKKLGVGLKRKLCFALSMLGSPRVTLLDEPSTGMDPKAKQRMWRAIRAAFKNKERAAILTTHYMEEADAVCDRVAILVAGQLRCIGTVQHLKSKFGRGYFLEMKLKDTADVQQVEYLQRQVLHIFPNANRQESFASILAYKIPREDVQSLSHCFSKLEEVKYAFNIEEYSFSQATLEQVFVELAKEQEEEEGSFGTLNSTLWWDRTQEDRVVF", "length": 1647, "header": "tr|A0A8V1ANP1-1|A0A8V1ANP1_CHICK Isoform 1 of Cholesterol transporter ABCA5 OS=Gallus gallus OX=9031 GN=ABCA5 PE=3 SV=1 CANONICAL=A0A8V1ANP1-1" }, "locus": { "chromosome": "18", "start_pos": 8606662, "end_pos": 8585082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071162.1", "url": "https://www.ensembl.org/id/ENSGALT00010071162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043853.1", "url": "https://www.ensembl.org/id/ENSGALP00010043853.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1358, "start_aa": "Thr", "end_pos": 1358, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1358", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417444", "resource": "KEGG Pathway" }, { "id": "R-GGA-1369062", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1369062", "resource": "Reactome", "description": "ABC transporters in lipid homeostasis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GGK0-1", "protein_name": "Cholesterol transporter ABCA5", "gene_name": "Abca5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATAIREVGVWRQTRTLLLKNYLVKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVSDIELSPMDKSSLSNLILGYTPVNNTTSSIMQRVSTDHLPDVIITEEYANEKEMLASSLSKSSNFVGVVFKDIMSYELRFFPDMIPVSSIYMDSRAGCSKSCDAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVLEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKLKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASSLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGAVEFFVTVAFGFVGLLIVLMENFPKSLVWLFSPFCQCTFLIGIAQVMHLEDFNDGALFSNLTEGPYPLIITIIMLALDSVFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKTKRNYKELSEGNINGNISLSEIIEPVSPEFIGKEAIRISGIQKAYRKGNENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTLFSTHFMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVRQHIPAATLLQQNDQQLVYSLPFKDMDKFSGLFSALDIHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQAVDYSVFTQQSVEEEMDSKSFDEMEQSLLILSETKASQVSTMSLWKQQMSTIAKFHFLTLKRESKSVRSVLLLLLIFFAVQIFMFLVHHSFKNAVVPIKLVPDLYFLRPGDKPHKYKTSLLLQNSTDSDISDLINFFTHQNIMVTMFNDSDYVSAAPHSAALNVVHSEKDYVFTAVFNSTMVYSLPVMMNIISNYYLYHLNVTEAIQIWSTPFIQEITDIVFKVELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWVGQTVVDFPLFFVVLTLMLGSLFAFHHGLYFYPVKFLAVVFCLVGYVPSVILFTYVASFTFKKILNTREFWSFIYSVTALACIAVTEITFFLGYSVSTVFHYTFCIAIPIYPLMGCLISFIKGSWKNIPKNEDTYNPWDKLLVAVIMPYLQCVLWIFLIQHYEKKHGGRSLRKDPFFRTLSQKAKSKKFPEPPVNEDEDEDVKAERLKVKELMSCQCCEEKPAIMVCNLHKEYDDKKDFLHSRKTKKVATKYISFCVRKGEILGLLGPNGAGKSTIINILVGDIEPTSGQIFLGDYISHSNEDDESSKCMGYCPQTNPLWPDITLQEHFEIYGAVKGMSSSDMKEVISRITNALDLKEHLQKTIKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEIDRLQREIQYIFPNASRQESFSSILAYKIPREDVQSLSQSFAKLEEAKHTFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF", "length": 1643 }, "evidence": [ { "id": "A0A8V1ANP1", "url": "https://omabrowser.org/oma/group/A0A8V1ANP1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1QEL5-1", "protein_name": "Cholesterol transporter ABCA5", "gene_name": "abca5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYFIPVSDPCGSQLKHAGRMQPLTRRDAGVWHQTRSLLYKNLLIKWRTKQQSLQELILPLLLLGLLILISTLNPHVSYGSISTKELEFERELPVKGLGYTPITNFTNHIMEEVARELSMNEHLDMFSTEADLENASLYEPEGYVGVVFLDSMSYRLRFPYSQLPLPSDFTESITSCYTNYVNCRAANYWYSGFIRLQSVIDAAIIQMKTKRPVWNELKVRAVMMGHPGSVEVQKFPHALISIYLVLAFTPFVSFLIVNVAAEKEQRLKDTMGMMGLYDSAFWLSWGLLYAALVTTMSILMAVIATCTPLFSNSNFFVIFLLIFLYGISSIFFSFMLTPLFKKPKFASTVGSMLTVVFGCLSLFTVLMRDFPQSAVWLLCLLSPSAFSIGIAQVVYLEAQGDGAVFSSLGNGPHALYVPLVMLFLDCILYLLLAIYLDQVLPGEFGTKRSVLYFLKPSYWSKRRKRYVEVSSVYEGEVNGTPAIDESVEAVSPEFRGKEVIRICNIRKIYREKDTKVEALRGLTFDIYEGQITALLGHSGAGKSTLMNILCGICPPTEGTATIYGSPVAEIAEGAEMKQLVGICPQFNIIFDVLTVEEHLRIFAAIKGILPSDIDGEVRKVLKDLDLEKIMDALAKNLSGGQKRKLSVGIAILGDPKILLLDEPTAGMDPVSRHQVWSLLKSRRAGRVTVLSTHYMDEADILADRKAVISQGQLKCVGSSLYLKTKCGVGYHLRMSVTEGCEVEGITSLVKQHVPKAQLSRQQEAELTFTLPFESMDTFPGLFAELDCRPDLGIINYGVSMTTLEDVFLRLEAEAEVDQADYSVFNQEKVEEEGDASSMDDTDQRLLTFSDSRQDTVTGHALWRQQFSTVAWLHMLNLQRERKPIIYNLTLFVVFLSAMLILSVATGNIQIHSPERLFSPIYLLRRNEAPHKYTTSLLVQNSTDSDLSGFIHNLQSQDIKVEMMKKLDYMSAAPVSAAINVTGPSKDFTYILAFNSTTVHSLPMAVNVLSNALLRGYNGTGHIRTWSKPFDYQIPDKTSYALVYIEAVILGMLAAGMPAYFAMDHTRDRELKCRSTLRISGLVPSAYWCGQAAIDVPFYYLILTCMTSTLFAFHSTNLLTSHNILSVALCLIGFSPAMVLFTYCVSFMFVRVQSNRDFFSVVSMMVCVVSASIVQLALVNESASMARLLHNALCFFSPLYPLMGCLNCITVATFVQSPHDDDFLWKNLFISVVAPYIQCILLLVSLRWLEIRYGGKTMKNDQLCRISSQAKSKAQRNPEENMSEDEDVQMEKARVKEAMTCQCCEEKPVVVVSNLRKQYKGKREGFSLNKKRKVATKNISFCVRKGEVLGLLGPNGAGKSTIMHMLSGDTEATAGQILMGDYGTDFQPAENPLEHVGYCPQVNPLWPRITLQEHLEIYSAIKGLRQRDIPNIIKRVVSALELKDHLYKQSKNLSAGLKRKLCFALSMLGNPQIVLLDEPSTGMDPKSKQRMWRAIRAAFKNKQRGALLTTHYMEEAEAVCDRVAIMVSGQLRCIGSIQHLKGKFGRGYSLEINLREELTGLQQVALLHKEILKIFPHAVRQDSFATMMVYKIPMEDVKSLAKSFAQLESAKQNFNFEEYNFSQSTLEQVFMEFAKEQENEEEEVGSLSTTFQWQRLRQDGPVSINHADSIVHQL", "length": 1673 }, "evidence": [ { "id": "A0A8V1ANP1", "url": "https://omabrowser.org/oma/group/A0A8V1ANP1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K448-1", "protein_name": "Cholesterol transporter ABCA5", "gene_name": "Abca5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATAIRDVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILVSMMHPNKKYEEVSDIELSPMDKFSLSNVILGYTPVTNITSSIMQRVSTDHLPKVIVTEEYANEKELVAASLSKSSNFVGVVFKDTMSYELRFFPEMIPVSSIYMNSREGCSKTCDAAQYWSLGFTVLQASIDAAIIQLKTNVSVWSELESTKAVIMGEAAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKLKEFLKIMGLHDTAFWLSWVLLYASLIFLMSLLMAVIATASSLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGVVEFFVTVVFGFVGLLIVLIESFPRSLVWLFSPLCQCAFLIGIAQVMHLEDFNEGALFSNLTEGPYPLIITIIMLALDSVFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKNKRNYKELSEGNINGNISLNEIVEPVSSEFIGKEAIRISGIQKSYRKKTENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQSDINFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQAIKDNQAKKLSGGQKRKLSVGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSIFLKSKWGIGYRLSMYIDRYCATESLSSLVRQHIPAAALLQQNDQQLVYSLPFKDMDKFSGLFSALDIHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPREEETDSKSFDEMEQSLLILSETKASSVSTMSLWKQQVSTIAKFHFLSLKRESKSVRAVLLLLLIFFAVQIFMFFLHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSTDSDINGLIEFFAHQNIMVAMFNDSDYVSAAPHSAALNVVRSEKDYVFSAVFNSTMVYCLPVMMNIISNYYLYHLNVTEAIQTWSTPFIQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWVGQAVVDIPLFFVVLILMLGSLFAFHHGLYFYPAKFLAVVFCLIAYVPSVILFTYIASFTFKKILNTKEFWSFIYSVTALACVAITETTFFLQYAVTAVFHYTFCIAIPIYPLLGCLISFIKGSWKNMPKNENTYNPWDRLLVAVIMPYLQCILWIFLLQHYEKIHGGRSIRKDPFFRALSQKAKNKKFPEPPINEDEDEDVKAERLKVKELMGCQCCEEKPAIMVCNLHKEYDDKKDFLHSRKTTKVATKYISFCVKKGEILGLLGPNGAGKSTVINTLVGDVEPTSGKIFLGDYGSHSSEDDESIKCMGYCPQTNPLWPDLTLQEHFEIYGAVKGMSPGDMKEVISRITKALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQVTLLDEPSTGMDPRAKQHMWRAIRTAFKNKKRAALLTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEIDRLQREIQYIFPNASRQESFSSILAFKIPKEDVQSLSQSFAKLEEAKRTFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLASTLWWERTQEDRVVF", "length": 1642 }, "evidence": [ { "id": "A0A8V1ANP1", "url": "https://omabrowser.org/oma/group/A0A8V1ANP1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WWZ7-1", "protein_name": "Cholesterol transporter ABCA5", "gene_name": "ABCA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELSEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF", "length": 1642 }, "evidence": [ { "id": "A0A8V1ANP1", "url": "https://omabrowser.org/oma/group/A0A8V1ANP1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "negative regulation of macrophage derived foam cell differentiation", "id": "GO:0010745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "cholesterol efflux", "id": "GO:0033344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "high-density lipoprotein particle remodeling", "id": "GO:0034375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "reverse cholesterol transport", "id": "GO:0043691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "regulation of cholesterol efflux", "id": "GO:0010874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" }, { "name": "positive regulation of reverse cholesterol transport", "id": "GO:1903064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1002, "end_pos": 1004, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1632, "end_pos": 1634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 923, "end_pos": 925, "annotation": "n_glycosylation_sequon" }, { "start_pos": 947, "end_pos": 949, "annotation": "n_glycosylation_sequon" }, { "start_pos": 979, "end_pos": 981, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "39051", "name": "", "equation": "cholesterol(in) + ATP + H2O = cholesterol(out) + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "39051", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/39051" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANP1" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 482, "end_pos": 717, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": 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"https://www.ebi.ac.uk/interpro/entry/IPR056581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANR2", "url": "https://www.orthodb.org/?gene=A0A8V1ANR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15571", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15571", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15571:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15571:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24293", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2", "database": 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"MEPGSGSGERVAPWGVCEETAILHGGFLLASRLLQPRPLRELLKAEWPLVGPPITDALREIGARCPSPRQHGLWKKEAVALVWAKVLLPAPPAASLDREWKEDAFFSVGAMIPDVNRTVLFELVKALGAARLFAQLLLALPPGVCRAELRHLVRYVGHETAPSDVGFLLDVWWEVVRHVRDPEDSTVTAFSSLVCEHGCECALDDGLQPPKRFKGDPSSLNGSPAADGLLVVLVEGLKQTYGSIASPRMRCYALGNLVELLSVFTELEPQGGPLPVAEYLAKVSSVVSLWSSDTESQHHHSGLDEKVKEAERTMSFASIAKLSREELIAGLDFLHCLLRAWGEELRGVLNSSENQCYESYWLLDTLPTFRKSLVCFSETGDLSEDEMRVALELAQTIDDFLKEISTTQKSKDLDTSLSSSVAMTIIEQKLQRHMEVCSIFASEKTWVFSKDWVDCLVKNRALFQKPELVLKLLETLVNFATSCEDREAQEMQMEVTKAIVECYSELSLTDKNEVISGVLEAWGGPGLSLNLQVVMEGFQEDLNVTFNQITKSVSDEGLTRAVAAVARLALLHPEATVKQICSLAVVNLGAHQFLAQILCSFPALSFLETCDDPCRPHSLVVRCLKEAAWEKLSSAREEEQFLEFLAFLMQPSSAAPLVSPAEVTKAFVLPYLKSDCAQIELSLQILSKVLGIQSYPDEHWIKSCHPFPLLLSLCKLLDGYTKYWHQPKDQLFPSLESKDLVLNVLGRICEVVTPETASSAEVWVQSLAWLHRKVASLDWTIGLRLKKFYGEHFKNEVPATLFEICTLPEDEWTSQPLPAYGPGSGLLAWMECCCVSTELRETMLSLLMVNVDNPEEVNLFSKGFLVALIQVLPWCSHSEWKRLVHVVTNLLERQVLHVPYTLEYVQYVPLLNLRPFACYLQLSVLFLRGFQLLCSSSCSTWLPPQAWLHVVQLYCSSLTDLLSSIKSITGPPLHPAEDRSSAEEVCFVCIQVFCHLLHVAAMLPPDSGCSEPLVVVALEVLSQYEVFSSADPSPSSVLRRANERHFLESITDNISDKALCGPLLQKLSKLGA", "length": 1072, "header": "tr|A0A8V1ANR2-1|A0A8V1ANR2_CHICK Isoform 1 of Gem nuclear organelle associated protein 4 OS=Gallus gallus OX=9031 GN=GEMIN4 PE=1 SV=1 CANONICAL=A0A8V1ANR2-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2/entry#A0A8V1ANR2-1", "sequence": { "sequence": 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"length": 1072, "header": "tr|A0A8V1ANR2-1|A0A8V1ANR2_CHICK Isoform 1 of Gem nuclear organelle associated protein 4 OS=Gallus gallus OX=9031 GN=GEMIN4 PE=1 SV=1 CANONICAL=A0A8V1ANR2-1" }, "locus": { "chromosome": "19", "start_pos": 7418120, "end_pos": 7414905, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072003.1", "url": "https://www.ensembl.org/id/ENSGALT00010072003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044693.1", "url": "https://www.ensembl.org/id/ENSGALP00010044693.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" } ], "pmid": "" }, { "name": "SMN complex", "id": "GO:0032797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032797", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1053, "end_pos": 1055, "annotation": "n_glycosylation_sequon" }, { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANR2" }, { "id": "PF24293", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Edg1/GEMIN4 TPR repeats region", "eco_id": "ECO_0000259", "start_pos": 418, "end_pos": 914, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1053, "end_pos": 1055 }, { "start_pos": 116, "end_pos": 118 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 350, "end_pos": 352 }, { "start_pos": 543, "end_pos": 545 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANT4-1", "uniprot_ac": "A0A8V1ANT4", "uniprot_id": "A0A8V1ANT4_CHICK", "mass": { "chemical_mass": 74013.0, "monoisotopic_mass": 74013.0 }, "refseq": { "ac": "XP_003642373", "name": "E3 ubiquitin-protein ligase TRIM47", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642373" }, "gene_names": [ { "name": "TRIM47", "type": "recommended", "evidence": [ { "id": "A0A8V1ANT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4" } ] }, { "name": "TRIM47", "type": "synonym", "evidence": [ { "id": "XP_003642373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642373" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM47", "type": "synonym", "evidence": [ { "id": "XP_003642373", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642373" } ] }, { "name": "Tripartite motif containing 47", "type": "synonym", "evidence": [ { "id": "A0A8V1ANT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642373.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642373" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM47", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4", "locus": {} } ], "crossref": [ { "id": "A0A8V1ANT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16604", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16604", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19842", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19842", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770100", "url": "https://www.ncbi.nlm.nih.gov/gene/770100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770100", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQVENIC", "url": "https://omabrowser.org/oma/group/VQVENIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANT4", "url": "https://www.orthodb.org/?gene=A0A8V1ANT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642373", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1ANT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGAPGRAPPVPSAATAAALRLALAVPGLPDGPFGCPICLDLLKDPVTVPCGHNFCQGCLGKLRGRTGPPDGAAGGAARCPLCQEPFPAALRLSKNRALCEVLPLLGAAGAGTSPDGARTPPAIPSPQSGPGSPPGSAGFSGTGPSGAESSPSEMAPGAEEEPGGEAELEEGAAAVLCDVCPEGDRAAAARSCLVCLASFCGAHLEPHRRSPAFRSHRLVAPLRRLEEGLCPRHLQPLDGFCRAEQTCVCVRCRANEHRGHDVVSLEKERELKEAQRAKFLSSVDNELEELAVTIAQTRKMVELIKGVASKEKERVEKLFAEASELLATFQKEVAAFIEDSERSMLGETEADLRWKEERRAKLAQGKQNLENIPSTDTIYFLQEFQALKIAMEDNLSPAPSFQNELNFTKCSQAVCAVKDALSAARKSQWDCLQGKGVDGMSFPKTEEAMTKSQFPDKSNNPACLESRDYFLKFAFIIDLDSDTADKFIQLFGTKGAKRVLCPIPYPESPTRFINCEQVLGVNLMNRGNYYWEVELIDGWVSIGVITEVFNPQDSYNHSRLGRNTSSCCLQWNGQNYAAWFGGLESVIQQPFFHTIGVFLEYSEKALTFYGVKDSKMTCLKQLKAGSFAKAQSDPFQHKINQQFASLFSFKLKPAFFLESVDAHLQIGPLKKDCVSVLKRR", "length": 681, "header": "tr|A0A8V1ANT4-1|A0A8V1ANT4_CHICK Isoform 1 of Tripartite motif containing 47 OS=Gallus gallus OX=9031 GN=TRIM47 PE=1 SV=1 CANONICAL=A0A8V1ANT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4/entry#A0A8V1ANT4-1", "sequence": { 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"database": "UniProtKB", "id": "A0A8V1ANT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1ANT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 226, "end_pos": 266, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ANT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 457, "end_pos": 674, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1ANT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANT4" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 84, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 395, "end_pos": 397 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 564, "end_pos": 566 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1ANU6-1", "uniprot_ac": "A0A8V1ANU6", "uniprot_id": "A0A8V1ANU6_CHICK", "mass": { "chemical_mass": 23533.0, "monoisotopic_mass": 23533.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "ODF3A protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ANU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU6", "locus": {} } ], "crossref": [ { "id": "A0A8V1ANU6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR010736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21580:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21580:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AD40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AD40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AD40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ANU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPGAAGPGPATLWSPPSPGTGSTWAPGAQLRGRPATKTTVTPGPSEYHLCSTSPRQDERAARFARGTLTLPLAHTLSAAPPAGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKVSSAAPLFRVSIRTWAAPPVPQGLPSLLQLCLTQTAGERESLECDPSPVWS", "length": 224, "header": "tr|A0A8V1ANU6-1|A0A8V1ANU6_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ANU6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AD40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU6/entry#A0A8V1AD40-1", "sequence": { "sequence": "SPGTGSTWAPGAQLRGRPATKTTVTPGPSEYHLCSTSPRQDERAARFPLAHTLSAAPPAGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVSEGSRGEKGPR", "length": 159, "header": "tr|A0A8V1AD40-1|A0A8V1AD40_CHICK Computationally mapped isoform of ODF3A protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ANU6-1" }, "locus": { "chromosome": "19", "start_pos": 191458, "end_pos": 189571, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071248.1", "url": "https://www.ensembl.org/id/ENSGALT00010071248.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043939.1", "url": "https://www.ensembl.org/id/ENSGALP00010043939.1" } ] } }, { "isoform_ac": "A0A8V1ANU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANU6/entry#A0A8V1ANU6-1", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPGAAGPGPATLWSPPSPGTGSTWAPGAQLRGRPATKTTVTPGPSEYHLCSTSPRQDERAARFARGTLTLPLAHTLSAAPPAGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKVSSAAPLFRVSIRTWAAPPVPQGLPSLLQLCLTQTAGERESLECDPSPVWS", "length": 224, "header": "tr|A0A8V1ANU6-1|A0A8V1ANU6_CHICK Isoform 1 of ODF3A protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1ANU6-1" }, "locus": { "chromosome": "19", "start_pos": 192250, "end_pos": 190249, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071249.1", "url": "https://www.ensembl.org/id/ENSGALT00010071249.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043940.1", "url": "https://www.ensembl.org/id/ENSGALP00010043940.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], 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"A0A8V1ANZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANZ6" } ] } ], "protein_names": [ { "name": "F-box domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1ANZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANZ6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1ANZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANZ6", "locus": {} } ], "crossref": [ { "id": "A0A8V1ANZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1ANZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ANZ6", "url": "https://www.orthodb.org/?gene=A0A8V1ANZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19872:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19872:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"MLSVGAGAPQPTKGLSHSQAMLSSGGVQKIRSTVCCSAAGLSSSMSCTQCLSLARTPGGQAPALRFCPPATSSPIPEGPGAEVASSTASSARADVHPRPTSLPSLSRVTYKDFIRCLPVHLSQYILGLLDNKSLKTCANVSRYWAFLAKEVEKEHVCQKAVQKKILYLQELCPMGAVPNYAKIVKVAIPQLNEKGCVIKVRDHSSESKTEEDKEEEENNLQAAYHDLQTDTIQLEERNVFCGSYSIRVLTDRSDPNRVIHYAGGDLVAIGSADRKVRIFNVLAMREVPPLLSGHAGSIKALLLDEKKGLVLSTSCDLSIRCWNIYSGACMKIFTGHCGAITCLDLHGKKFVSGGTDGMVKVWNLDSGVCLWTLKHSNVVYAVKMNGTHAVSGCDRGLVKVWHAGTGTLLKVLEGHLGPVRCLSFDQWHLVSGSSDGYAFGWSMVGDLKRCLTAFRHPKEVLSLELLFLRVVSGCADGKIRVFNYLTGSCLRVLVGSSRGDSISFCAAKNRMVINAPSSLLMFQFEDVMWDYMLGAEREMVWKEKQESCPLGTALTPSQQTKSHIASQMRRLTLKTRALCNEMIKPAACQQQEHLLGSRRSSHIQAEQQELFAPDGASEYGTSVLAHPDRHQEEKKGSLSSYKFLLTVSMLQKSGKPSFVRSITKHSSATEKALECLLQQQQKRQIYITSLQQKKDLMAQFQRARSYSDSLTMKRISVPFETKMLQLKLKNSLHGPTVNSSIPAPCIVRLKTCGALLQGKKAHGARSKGTSLPADRVQHSSRCTASERIKSTRAMIPQMKKEAVCRGKKNFCPFAADPSQADSGFRLLTGQQEEARAAAAVAQCQANQAKLLDHERAGKKAWLRKTKGLPTVSFTKEGKIVAPELGLNTFI", "length": 890, "header": "tr|A0A8V1ANZ6-1|A0A8V1ANZ6_CHICK Isoform 1 of F-box domain-containing protein OS=Gallus gallus OX=9031 GN=CDRT1 PE=4 SV=1 CANONICAL=A0A8V1ANZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1ANZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANZ6/entry#A0A8V1ANZ6-1", "sequence": { "sequence": "MLSVGAGAPQPTKGLSHSQAMLSSGGVQKIRSTVCCSAAGLSSSMSCTQCLSLARTPGGQAPALRFCPPATSSPIPEGPGAEVASSTASSARADVHPRPTSLPSLSRVTYKDFIRCLPVHLSQYILGLLDNKSLKTCANVSRYWAFLAKEVEKEHVCQKAVQKKILYLQELCPMGAVPNYAKIVKVAIPQLNEKGCVIKVRDHSSESKTEEDKEEEENNLQAAYHDLQTDTIQLEERNVFCGSYSIRVLTDRSDPNRVIHYAGGDLVAIGSADRKVRIFNVLAMREVPPLLSGHAGSIKALLLDEKKGLVLSTSCDLSIRCWNIYSGACMKIFTGHCGAITCLDLHGKKFVSGGTDGMVKVWNLDSGVCLWTLKHSNVVYAVKMNGTHAVSGCDRGLVKVWHAGTGTLLKVLEGHLGPVRCLSFDQWHLVSGSSDGYAFGWSMVGDLKRCLTAFRHPKEVLSLELLFLRVVSGCADGKIRVFNYLTGSCLRVLVGSSRGDSISFCAAKNRMVINAPSSLLMFQFEDVMWDYMLGAEREMVWKEKQESCPLGTALTPSQQTKSHIASQMRRLTLKTRALCNEMIKPAACQQQEHLLGSRRSSHIQAEQQELFAPDGASEYGTSVLAHPDRHQEEKKGSLSSYKFLLTVSMLQKSGKPSFVRSITKHSSATEKALECLLQQQQKRQIYITSLQQKKDLMAQFQRARSYSDSLTMKRISVPFETKMLQLKLKNSLHGPTVNSSIPAPCIVRLKTCGALLQGKKAHGARSKGTSLPADRVQHSSRCTASERIKSTRAMIPQMKKEAVCRGKKNFCPFAADPSQADSGFRLLTGQQEEARAAAAVAQCQANQAKLLDHERAGKKAWLRKTKGLPTVSFTKEGKIVAPELGLNTFI", "length": 890, "header": "tr|A0A8V1ANZ6-1|A0A8V1ANZ6_CHICK Isoform 1 of F-box domain-containing protein OS=Gallus gallus OX=9031 GN=CDRT1 PE=4 SV=1 CANONICAL=A0A8V1ANZ6-1" }, "locus": { "chromosome": "18", "start_pos": 2873719, "end_pos": 2862103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072344.1", "url": "https://www.ensembl.org/id/ENSGALT00010072344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044811.1", "url": "https://www.ensembl.org/id/ENSGALP00010044811.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 738, "end_pos": 740 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AP01-1", "uniprot_ac": "A0A8V1AP01", "uniprot_id": "A0A8V1AP01_CHICK", "mass": { "chemical_mass": 35265.0, "monoisotopic_mass": 35265.0 }, "refseq": { "ac": "XP_415703", "name": "tetraspanin-10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415703" }, "gene_names": [ { "name": "TSPAN10", "type": "recommended", "evidence": [ { "id": "A0A8V1AP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01" } ] }, { "name": "TSPAN10", "type": "synonym", "evidence": [ { "id": "XP_415703", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415703" } ] } ], "protein_names": [ { "name": "Tetraspanin 10", "type": "synonym", "evidence": [ { "id": "A0A8V1AP01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01/entry#names_and_taxonomy" } ] }, { "name": "tetraspanin-10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415703", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415703" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415703.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415703" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSPAN10", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01", "locus": { "chromosome": "18", "start_pos": 9778696, "end_pos": 9780979, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029512", "url": "https://www.ensembl.org/id/ENSGALG00010029512" } ] } } ], "crossref": [ { "id": "A0A8V1AP01", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP01", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417455", "url": "https://www.ncbi.nlm.nih.gov/gene/417455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417455", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417455", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLDPVPW", "url": "https://omabrowser.org/oma/group/CLDPVPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP01", "url": "https://www.orthodb.org/?gene=A0A8V1AP01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282:SF550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282:SF550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415703", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AP01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAAALRSSMVLGREQLSQFFRPYGEVGSGESSRLLPQTSQLAELPQSSDDDDDISLLGGADDPVAKHDMEEWCKPSAFSHCVRHLAFLWNLLFLLLGLLTLGIGVWGLLAKGWLQGERSAPLGSDPMLLFVLAGLGASTVSLAGCLGVLRSSTCLLRFFVGAVLAFVGLEVLGGLLLLVARQRLQDALQDALLLCLLRYQEEPDLRFLVDEVQRSLRCCGLSSYRDWESNPYFNCSAPGVQACSVPASCCLDPWQNGSITNDQCAFGVLHLGDVAAAGVVHLGGCVVQLGAWLRGQAGGIATGAAVLVLLEATGLLLALKVLADIVPGGTRG", "length": 333, "header": "tr|A0A8V1AP01-1|A0A8V1AP01_CHICK Isoform 1 of Tetraspanin 10 OS=Gallus gallus OX=9031 GN=TSPAN10 PE=1 SV=1 CANONICAL=A0A8V1AP01-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AP01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01/entry#A0A8V1AP01-1", "sequence": { "sequence": "MTAAALRSSMVLGREQLSQFFRPYGEVGSGESSRLLPQTSQLAELPQSSDDDDDISLLGGADDPVAKHDMEEWCKPSAFSHCVRHLAFLWNLLFLLLGLLTLGIGVWGLLAKGWLQGERSAPLGSDPMLLFVLAGLGASTVSLAGCLGVLRSSTCLLRFFVGAVLAFVGLEVLGGLLLLVARQRLQDALQDALLLCLLRYQEEPDLRFLVDEVQRSLRCCGLSSYRDWESNPYFNCSAPGVQACSVPASCCLDPWQNGSITNDQCAFGVLHLGDVAAAGVVHLGGCVVQLGAWLRGQAGGIATGAAVLVLLEATGLLLALKVLADIVPGGTRG", "length": 333, "header": "tr|A0A8V1AP01-1|A0A8V1AP01_CHICK Isoform 1 of Tetraspanin 10 OS=Gallus gallus OX=9031 GN=TSPAN10 PE=1 SV=1 CANONICAL=A0A8V1AP01-1" }, "locus": { "chromosome": "18", "start_pos": 9780395, "end_pos": 9778796, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071334.1", "url": "https://www.ensembl.org/id/ENSGALT00010071334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044025.1", "url": "https://www.ensembl.org/id/ENSGALP00010044025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417455", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R8X9-1", "protein_name": "Tetraspanin-10", "gene_name": "Tspan10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMAEEESSPLLSQDTAGQEYPLTRDSLPAANITYPTLWKNQKGAWGCRCCPGAKHQSWRGGQASSLPLSTGSSCVKYLIFLSNFLFSLPALLALAAGLWGLAVKRSQGSGWGEPLPTDPMLVLMLGGLVVSVVSLSGCLGAFCENSCLLHCYYGAVLSCLALEALAGALVVTLWDPLQDSLKRTLHLAIIHYWNDPDLHFLLDQVQLGLQCCGAESYQDWQQNLYFNCSSPGVQACSLPASCCINLQEDGAVVNTQCGLGALHLDPNAAGQVVYLQGCWPVLQEWLRGNVGAIGGCAVAVIMIQGTELLLAACLLRALAVHKAQRT", "length": 326 }, "evidence": [ { "id": "A0A8V1AP01", "url": "https://omabrowser.org/oma/group/A0A8V1AP01/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCF5-1", "protein_name": "Tetraspanin-10", "gene_name": "Tspan10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMKEEECSPLLSQDTAGREHPLTRNSPPTANIPCPAPWENQKGSWGCRCCPGAKRQASGEGQASSLPLSTGSNCVKYLIFLSNFLFSLPSLLALAAGLWGLTVKRSQGIGWGGPVPTDPMLMLVLGGLVVSVVSLSGCLGAFCENSCLLHWYCGAVLFCLALEALAGVLMVTLWKPLQDSLKYTLHAAIIHYWDDPDLHFLLDQVQLGLQCCGAVSYQDWQQNLYFNCSSPGVQACSLPASCCINPQEDGAVVNTQCGFGALGLDQNVAGQVVFLQGCWPALQEWLRGNTGAIGDCAVAVVMIQGTELLLAACLLRALAVHEAAEDIEAGPL", "length": 332 }, "evidence": [ { "id": "A0A8V1AP01", "url": "https://omabrowser.org/oma/group/A0A8V1AP01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP01", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 257, "end_pos": 259 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AP18-1", "uniprot_ac": "A0A8V1AP18", "uniprot_id": "A0A8V1AP18_CHICK", "mass": { "chemical_mass": 33196.0, "monoisotopic_mass": 33196.0 }, "refseq": { "ac": "XP_040505646", "name": "myeloid-associated differentiation marker-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505646" }, "gene_names": [ { "name": "MYADML2", "type": "recommended", "evidence": [ { "id": "A0A8V1AP18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18" } ] }, { "name": "MYADML2", "type": "synonym", "evidence": [ { "id": "XP_040505646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505646" } ] } ], "protein_names": [ { "name": "Myeloid-associated differentiation marker-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V1AP18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18/entry#names_and_taxonomy" } ] }, { "name": "myeloid-associated differentiation marker-like protein 2", "type": "synonym", "evidence": [ { "id": "XP_040505646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505646" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040505646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505646" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYADML2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18", "locus": { "chromosome": "18", "start_pos": 5686445, "end_pos": 5683769, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029948", "url": "https://www.ensembl.org/id/ENSGALG00010029948" } ] } } ], "crossref": [ { "id": "A0A8V1AP18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP18", "database": "AlphaFoldDB", "categories": [] }, { "id": "121106440", "url": "https://www.ncbi.nlm.nih.gov/gene/121106440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TGGPYLN", "url": "https://omabrowser.org/oma/group/TGGPYLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP18", "url": "https://www.orthodb.org/?gene=A0A8V1AP18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17068:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17068:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040505646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040505646", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AP18", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMESTGGPYLNTAAVTSPVGIVRLLQMMFGCTTFSLVAHQGGFSAAYGTFCMFVWTFCFSVTVFIITCEFTHLHSCLSISWGNFTAAFAMLATLMSVTAAVIYPLYFVQLGCYPITCEVRDFRIAASIFAGLVFVVYGAEVFLTRAKPGQVTSYMATVSGLLKIVQAFVACIIFGALVNDSQYSKYVATQWCVAVYSFCFMVTVVVVAFSVTGKTAQLCFPFERSVVVYTFGAVLLYVSAAVIWPVFCFDSKYGSPQRPSACAKGRCPWDSQLVVAIFTYVNLLLYVVDLAYSQRIRFVSHI", "length": 302, "header": "tr|A0A8V1AP18-1|A0A8V1AP18_CHICK Isoform 1 of Myeloid-associated differentiation marker-like protein 2 OS=Gallus gallus OX=9031 GN=MYADML2 PE=3 SV=1 CANONICAL=A0A8V1AP18-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AP18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18/entry#A0A8V1AP18-1", "sequence": { "sequence": "MMESTGGPYLNTAAVTSPVGIVRLLQMMFGCTTFSLVAHQGGFSAAYGTFCMFVWTFCFSVTVFIITCEFTHLHSCLSISWGNFTAAFAMLATLMSVTAAVIYPLYFVQLGCYPITCEVRDFRIAASIFAGLVFVVYGAEVFLTRAKPGQVTSYMATVSGLLKIVQAFVACIIFGALVNDSQYSKYVATQWCVAVYSFCFMVTVVVVAFSVTGKTAQLCFPFERSVVVYTFGAVLLYVSAAVIWPVFCFDSKYGSPQRPSACAKGRCPWDSQLVVAIFTYVNLLLYVVDLAYSQRIRFVSHI", "length": 302, "header": "tr|A0A8V1AP18-1|A0A8V1AP18_CHICK Isoform 1 of Myeloid-associated differentiation marker-like protein 2 OS=Gallus gallus OX=9031 GN=MYADML2 PE=3 SV=1 CANONICAL=A0A8V1AP18-1" }, "locus": { "chromosome": "18", "start_pos": 5685224, "end_pos": 5684319, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072379.1", "url": "https://www.ensembl.org/id/ENSGALT00010072379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044846.1", "url": "https://www.ensembl.org/id/ENSGALP00010044846.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1QNB6-1", "protein_name": "Myeloid-associated differentiation marker-like protein 2", "gene_name": "myadml2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDPQGGHYLNKSAVLSCLGAARMCQLLLGCTTMALVAHSAGFSATYGTFCMFVWCFCFAVTLLVFTLDVTRLHGCMPISWDNFTVAFAMLATLMYVTASVVYPVYFLRSDCPSQGCEVRNYRIAVTVCSSVCCFAYGAEVFITRAKPGHVVGYMATVSGLLKVVQAFIACIIFGALHNDSQYNRHIPTQYCVVVYSLCFAVTVVVVALTVSGRTSSLRFPFDRFVVIYTFLAVLLYLSAAVIWPVFSFDKKYGAPGRPDDCPKGKCPWDSKLVIAVFTCANLVLYFTDLVYSQRIRFVLSSAA", "length": 303 }, "evidence": [ { "id": "A0A8V1AP18", "url": "https://omabrowser.org/oma/group/A0A8V1AP18/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G5E500-1", "protein_name": "Myeloid-associated differentiation marker-like protein 2", "gene_name": "MYADML2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V1AP18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AP18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP18" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 149, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"ENSGALP00010044056.1", "url": "https://www.ensembl.org/id/ENSGALP00010044056.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 234, "start_aa": "Thr", "end_pos": 234, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr234", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 500, "start_aa": "Thr", "end_pos": 500, "end_aa": 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"" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 716, "end_pos": 718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AP32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP32" }, { "id": "SM01302", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01302" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Raptor N-terminal CASPase-like", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 207, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 716, "end_pos": 718 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 738, "end_pos": 740 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AP40-1", "uniprot_ac": "A0A8V1AP40", "uniprot_id": "A0A8V1AP40_CHICK", "mass": { "chemical_mass": 27752.0, "monoisotopic_mass": 27752.0 }, "refseq": { "ac": "NP_990264", "name": "fibrinogen-like protein 1-like protein precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264" }, "gene_names": [ { "name": "ANGPT1L", "type": "recommended", "evidence": [ { "id": "A0A8V1AP40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40" } ] }, { "name": "ANGPT1L", "type": "synonym", "evidence": [ { "id": "NP_990264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264" } ] }, { "name": "CDD", "type": "synonym", "evidence": [ { "id": "NP_990264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264" } ] } ], "protein_names": [ { "name": "Angiopoietin-related protein 1-like", "type": "synonym", "evidence": [ { "id": "A0A8V1AP40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40/entry#names_and_taxonomy" } ] }, { "name": "cytidine deaminase", "type": "synonym", "evidence": [ { "id": "NP_990264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264" } ] }, { "name": "fibrinogen-like protein 1-like protein precursor", "type": "synonym", "evidence": [ { "id": "NP_990264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264" } ] }, { "name": "fibrinogen-like protein 1-like protein", "type": "synonym", "evidence": [ { "id": "NP_990264", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF059262.1, BU123116.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000323.1. On Sep 23, 2021 this sequence version replaced NP_990264.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANGPT1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40", "locus": { "chromosome": "19", "start_pos": 728781, "end_pos": 726965, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029535", "url": "https://www.ensembl.org/id/ENSGALG00010029535" } ] } } ], "crossref": [ { "id": "A0A8V1AP40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395773", "url": "https://www.ncbi.nlm.nih.gov/gene/395773", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395773", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395773", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AP40", "url": "https://www.orthodb.org/?gene=A0A8V1AP40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990264", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990264", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLQAGTRQLHGNLILLPVAVVMLLLCTSPVCATASVGLPADCSRLTSSSPSGVYVIQPAQSPPRVVWCDMDTEGKGWTVVQRNTYSTEITWKESWTTYKYGFGNVQGDHWLGTEYLHLLTQQGTYKVRFVVRDKANVTHYAEYDIFRVESESSGYPLRLGRLLSSGKDYLTSYYSSYGGIHDNMKFSTVDKDQDQHSGNCASSYGGWWYDRCQNVLLNGKKYILWPEICPRGDCVSSLILVKPTDVC", "length": 248, "header": "tr|A0A8V1AP40-1|A0A8V1AP40_CHICK Isoform 1 of Angiopoietin-related protein 1-like OS=Gallus gallus OX=9031 GN=ANGPT1L PE=4 SV=1 CANONICAL=A0A8V1AP40-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AP40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40/entry#A0A8V1AP40-1", "sequence": { "sequence": "MGLQAGTRQLHGNLILLPVAVVMLLLCTSPVCATASVGLPADCSRLTSSSPSGVYVIQPAQSPPRVVWCDMDTEGKGWTVVQRNTYSTEITWKESWTTYKYGFGNVQGDHWLGTEYLHLLTQQGTYKVRFVVRDKANVTHYAEYDIFRVESESSGYPLRLGRLLSSGKDYLTSYYSSYGGIHDNMKFSTVDKDQDQHSGNCASSYGGWWYDRCQNVLLNGKKYILWPEICPRGDCVSSLILVKPTDVC", "length": 248, "header": "tr|A0A8V1AP40-1|A0A8V1AP40_CHICK Isoform 1 of Angiopoietin-related protein 1-like OS=Gallus gallus OX=9031 GN=ANGPT1L PE=4 SV=1 CANONICAL=A0A8V1AP40-1" }, "locus": { "chromosome": "19", "start_pos": 728663, "end_pos": 727025, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071396.1", "url": "https://www.ensembl.org/id/ENSGALT00010071396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044086.1", "url": "https://www.ensembl.org/id/ENSGALP00010044086.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395773", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395773", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AP40", "database": 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"name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V1AP63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP63/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP63" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP63", "locus": {} } ], "crossref": [ { "id": "A0A8V1AP63", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP63", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V1AP63", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKPIFGSPLLSLTWDCTHLHKYPFVLQNTNSPTHPGLQLLELFLASLQGQLLCLIQCSLCVSQVLLCLCSHAVGMAQLDLHFVQVSLHLLLQPQGLIPAPDLSIQGALHGLHNSEVISLQLVNFLIFLCYLPVNLRLDLVELQLEAQDLPLFMFQGGLEKS", "length": 162, "header": "tr|A0A8V1AP63-1|A0A8V1AP63_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A8V1AP63-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AP63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP63/entry#A0A8V1AP63-1", "sequence": { "sequence": "MLKPIFGSPLLSLTWDCTHLHKYPFVLQNTNSPTHPGLQLLELFLASLQGQLLCLIQCSLCVSQVLLCLCSHAVGMAQLDLHFVQVSLHLLLQPQGLIPAPDLSIQGALHGLHNSEVISLQLVNFLIFLCYLPVNLRLDLVELQLEAQDLPLFMFQGGLEKS", "length": 162, "header": "tr|A0A8V1AP63-1|A0A8V1AP63_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=A0A8V1AP63-1" }, "locus": { "chromosome": "18", "start_pos": 1186065, "end_pos": 1183838, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071436.1", "url": "https://www.ensembl.org/id/ENSGALT00010071436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044126.1", "url": "https://www.ensembl.org/id/ENSGALP00010044126.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AP82-1", "uniprot_ac": "A0A8V1AP82", "uniprot_id": "A0A8V1AP82_CHICK", "mass": { "chemical_mass": 83475.0, "monoisotopic_mass": 83475.0 }, "refseq": {}, "gene_names": [ { "name": "EPX", "type": "recommended", "evidence": [ { "id": "A0A8V1AP82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ] } ], "protein_names": [ { "name": "Eosinophil peroxidase", "type": "synonym", "evidence": [ { "id": "A0A8V1AP82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EPX", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82", "locus": { "chromosome": "19", "start_pos": 952780, "end_pos": 963918, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029571", "url": "https://www.ensembl.org/id/ENSGALG00010029571" } ] } } ], "crossref": [ { "id": "A0A8V1AP82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AP82", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000043254", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000043254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09824", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09824", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417467", "url": "https://www.ncbi.nlm.nih.gov/gene/417467", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "INCEESC", "url": "https://omabrowser.org/oma/group/INCEESC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TU19", "url": "https://www.orthodb.org/?gene=A0A3Q2TU19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP82", "url": "https://www.orthodb.org/?gene=A0A8V1AP82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11475", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11475", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11475:SF63", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11475:SF63", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8941413", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8941413", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TU19", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TU19-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TU19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAETCFLVLLAKIILFRGSASSSYDLPEKLSDAFLLSSVDEAKQLVDSAYKDTRDRIKKNLENDALNPIELLRYFKQPVAGTRAAIRAADYMGTTLTLLKEKLSRVVKGDFNVTDMLTPAQMGLLFKVTGCEEQNKKVNCEFSSRYRTITGKCNNRRNPLLGASNRALARWLPADYEDGVSIPHGWTNRRCSFGYPFPLVRRVSNEIVRFPPGQLKFDQQRSLMFMQWGQFIDHDLDFSPESPARVTFNGRVDCHTSCAKLPPCFPIQIPPNDPRIKNTRDCIPFFRSAPACDSGRATREQINALTSFLDGSMVYGSEQHLANRLRNWNNQLGLLAVNQNFTDNGMAYLPFVRMSKDPCLKVSGSANIPCFLAGDSRASEMLELACMHTLFVREHNRLAIGLKRLNPHWNGERIYQEARKIVGAMIQIITYRDYLPLLLGRNLQRWIPSYKGYKESVDPRISNVFTLAFRFAHASIPPSVGRLNQNYQSTYPKLKLSKTFFGVWHIVKGGGIDPFLRNLMASKAKLMTQDQMMVDELRDHLSEQIERIGLDLAALNMQRGRDHGLPGYVSWRKFCGLPQPYDVRSLGQVLKNKNLARKFMKLYGTPRNIDIWVGALAEPFVDGGRVGPLMACLIGTQFRNTRDGDRFWWENTGVFTAQQRSSLAKISLSRIICDNTHITKVSRNIFQANSYPHSFVSCSSIPKLDLRAWKSNCMEESTEQGISLKEQTVPACKQV", "length": 736, "header": "tr|A0A8V1AP82-1|A0A8V1AP82_CHICK Isoform 1 of Eosinophil peroxidase OS=Gallus gallus OX=9031 GN=EPX PE=1 SV=1 CANONICAL=A0A8V1AP82-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TU19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82/entry#A0A3Q2TU19-1", "sequence": { "sequence": "MKAETCFLVLLAKIILFRGSASSSYDLPEKLSDAFLLSSVDEAKQLVDSAYKDTRDRIKKNLENDALNPIELLRYFKQPVAGTRAAIRAADYMGTTLTLLKEKLSRVVKGDFNVTDMLTPAQMGLLFKVTGCEEQNKKVNCEFSSRYRTITGKCNNRRNPLLGASNRALARWLPADYEDGVSIPHGWTNRRCSFGYPFPLVRRVSNEIVRFPPGQLKFDQQRSLMFMQWGQFIDHDLDFSPESPARVTFNGRVDCHTSCAKLPPCFPIQIPPNDPRIKNTRDCIPFFRSAPACDSGRATREQINALTSFLDGSMVYGSEQHLANRLRNWNNQLGLLAVNQNFTDNGMAYLPFVRMSKDPCLKVSGSANIPCFLAGDSRASEMLELACMHTLFVREHNRLAIGLKRLNPHWNGERIYQEARKIVGAMIQIITYRDYLPLLLGRNLQRWIPSYKGYKESVDPRISNVFTLAFRFAHASIPPSVGRLNQNYQSTYPKLKLSKTFFGVWHIVKGGGIDPFLRNLMASKAKLMTQDQMMVDELRDHLSEQIERIGLDLAALNMQRGRDHGLPGYVSWRKFCGLPQPYDVRSLGQVLKNKNLARKFMKLYGTPRNIDIWVGALAEPFVDGGRVGPLMACLIGTQFRNTRDGDRFWWENTGVFTAQQRSSLAKISLSRIICDNTHITKVSRNIFQANSYPHSFVSCSSIPKLDLRAWKSNCMEESTEQEETPGDQ", "length": 728, "header": "tr|A0A3Q2TU19-1|A0A3Q2TU19_CHICK Computationally mapped isoform of Eosinophil peroxidase OS=Gallus gallus OX=9031 GN=EPX PE=1 SV=1 CANONICAL=A0A8V1AP82-1" }, "locus": { "chromosome": "19", "start_pos": 963682, "end_pos": 953415, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071467.1", "url": "https://www.ensembl.org/id/ENSGALT00010071467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044157.1", "url": "https://www.ensembl.org/id/ENSGALP00010044157.1" } ] } }, { "isoform_ac": "A0A8V1AP82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82/entry#A0A8V1AP82-1", "sequence": { "sequence": "MKAETCFLVLLAKIILFRGSASSSYDLPEKLSDAFLLSSVDEAKQLVDSAYKDTRDRIKKNLENDALNPIELLRYFKQPVAGTRAAIRAADYMGTTLTLLKEKLSRVVKGDFNVTDMLTPAQMGLLFKVTGCEEQNKKVNCEFSSRYRTITGKCNNRRNPLLGASNRALARWLPADYEDGVSIPHGWTNRRCSFGYPFPLVRRVSNEIVRFPPGQLKFDQQRSLMFMQWGQFIDHDLDFSPESPARVTFNGRVDCHTSCAKLPPCFPIQIPPNDPRIKNTRDCIPFFRSAPACDSGRATREQINALTSFLDGSMVYGSEQHLANRLRNWNNQLGLLAVNQNFTDNGMAYLPFVRMSKDPCLKVSGSANIPCFLAGDSRASEMLELACMHTLFVREHNRLAIGLKRLNPHWNGERIYQEARKIVGAMIQIITYRDYLPLLLGRNLQRWIPSYKGYKESVDPRISNVFTLAFRFAHASIPPSVGRLNQNYQSTYPKLKLSKTFFGVWHIVKGGGIDPFLRNLMASKAKLMTQDQMMVDELRDHLSEQIERIGLDLAALNMQRGRDHGLPGYVSWRKFCGLPQPYDVRSLGQVLKNKNLARKFMKLYGTPRNIDIWVGALAEPFVDGGRVGPLMACLIGTQFRNTRDGDRFWWENTGVFTAQQRSSLAKISLSRIICDNTHITKVSRNIFQANSYPHSFVSCSSIPKLDLRAWKSNCMEESTEQGISLKEQTVPACKQV", "length": 736, "header": "tr|A0A8V1AP82-1|A0A8V1AP82_CHICK Isoform 1 of Eosinophil peroxidase OS=Gallus gallus OX=9031 GN=EPX PE=1 SV=1 CANONICAL=A0A8V1AP82-1" }, "locus": { "chromosome": "19", "start_pos": 963682, "end_pos": 953784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071468.1", "url": "https://www.ensembl.org/id/ENSGALT00010071468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044158.1", "url": "https://www.ensembl.org/id/ENSGALP00010044158.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-8941413", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8941413", "resource": "Reactome", "description": "Events associated with phagocytolytic activity of PMN cells" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ], "pmid": "" }, { "name": "peroxidase activity", "id": "GO:0004601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1API4-1", "uniprot_ac": "A0A8V1API4", "uniprot_id": "A0A8V1API4_CHICK", "mass": { "chemical_mass": 21302.0, "monoisotopic_mass": 21302.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Peptidase S54 rhomboid domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V1API4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4", "locus": {} } ], "crossref": [ { "id": "A0A8V1API4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1API4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR022764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF01694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1API4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1API4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLSSTGLGPCGALCHAAPPGPHRPAVLLSQFPVLPHAYVCGSGRSAEWGHAWFLPAVVPSDAFSVHRLVTYIFVYEDLISLTCGAVVIWYFAGSFEKNVGTVKHCFFTLVFADITGGACFWLNYSLGCDLCQSLHRITSQECWNICHIQTSVGAAHYKLKMSHSRPFNAYFLNWGKVALMKRNLSTGVDVQE", "length": 193, "header": "tr|A0A8V1API4-1|A0A8V1API4_CHICK Isoform 1 of Peptidase S54 rhomboid domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1API4-1" }, "isoforms": [ { "isoform_ac": "A0A8V1API4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4/entry#A0A8V1API4-1", "sequence": { "sequence": "MWLSSTGLGPCGALCHAAPPGPHRPAVLLSQFPVLPHAYVCGSGRSAEWGHAWFLPAVVPSDAFSVHRLVTYIFVYEDLISLTCGAVVIWYFAGSFEKNVGTVKHCFFTLVFADITGGACFWLNYSLGCDLCQSLHRITSQECWNICHIQTSVGAAHYKLKMSHSRPFNAYFLNWGKVALMKRNLSTGVDVQE", "length": 193, "header": "tr|A0A8V1API4-1|A0A8V1API4_CHICK Isoform 1 of Peptidase S54 rhomboid domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V1API4-1" }, "locus": { "chromosome": "19", "start_pos": 4831943, "end_pos": 4829565, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071622.1", "url": "https://www.ensembl.org/id/ENSGALT00010071622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044312.1", "url": "https://www.ensembl.org/id/ENSGALP00010044312.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1API4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API4" }, { "id": "PF01694", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01694" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S54 rhomboid", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 123, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 184, "end_pos": 186 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1API8-1", "uniprot_ac": "A0A8V1API8", "uniprot_id": "A0A8V1API8_CHICK", "mass": { "chemical_mass": 26534.0, "monoisotopic_mass": 26534.0 }, "refseq": {}, "gene_names": [ { "name": "RASL10B", "type": "recommended", "evidence": [ { "id": "A0A8V1API8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8V1API8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V1API8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASL10B", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8", "locus": { "chromosome": "19", "start_pos": 4870152, "end_pos": 4875924, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029624", "url": "https://www.ensembl.org/id/ENSGALG00010029624" } ] } } ], "crossref": [ { "id": "A0A8V1API8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1API8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002086", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002086", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04142", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04142", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771592", "url": "https://www.ncbi.nlm.nih.gov/gene/771592", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771592", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771592", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IEMEIHI", "url": "https://omabrowser.org/oma/group/IEMEIHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1API8", "url": "https://www.orthodb.org/?gene=A0A8V1API8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BR34", "url": "https://www.orthodb.org/?gene=E1BR34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46350", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46350", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46350:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46350:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1API8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BR34", "url": "https://www.uniprot.org/uniprotkb/E1BR34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BR34-1", "url": "https://www.uniprot.org/uniprotkb/E1BR34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVATFKIAVLGAQGVGKSAIVRQFLYNEFSEVCVPTTARRVYLPAVVMNGHVHDLQIMDFPPIPAFPVNTLQEWADVCCRGLRSVHAYILVYDICCFDSFEYIKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSNLVKKTWKCGYIECSAKYNWHILLLFSELLKSVGCARCKHVHTTIRFQGALRRNRCTIIITPLPKNVGRGLAANRGQDIPIHSSNGAPLSSP", "length": 236, "header": "tr|A0A8V1API8-1|A0A8V1API8_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RASL10B PE=4 SV=1 CANONICAL=A0A8V1API8-1" }, "isoforms": [ { "isoform_ac": "A0A8V1API8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8/entry#A0A8V1API8-1", "sequence": { "sequence": "MVATFKIAVLGAQGVGKSAIVRQFLYNEFSEVCVPTTARRVYLPAVVMNGHVHDLQIMDFPPIPAFPVNTLQEWADVCCRGLRSVHAYILVYDICCFDSFEYIKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSNLVKKTWKCGYIECSAKYNWHILLLFSELLKSVGCARCKHVHTTIRFQGALRRNRCTIIITPLPKNVGRGLAANRGQDIPIHSSNGAPLSSP", "length": 236, "header": "tr|A0A8V1API8-1|A0A8V1API8_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RASL10B PE=4 SV=1 CANONICAL=A0A8V1API8-1" }, "locus": { "chromosome": "19", "start_pos": 4874134, "end_pos": 4870527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071627.1", "url": "https://www.ensembl.org/id/ENSGALT00010071627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044317.1", "url": "https://www.ensembl.org/id/ENSGALP00010044317.1" } ] } }, { "isoform_ac": "E1BR34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8/entry#E1BR34-1", "sequence": { "sequence": "MVATFKIAVLGAQGVGKSAIVRQFLYNEFSEVCVPTTARRVYLPAVVMNGHVHDLQIMDFPPIPAFPVNTLQEWADVCCRGLRSVHAYILVYDICCFDSFEYIKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSNLVKKTWKCGYIECSAKYNWHILLLFSELLKSVGCARCKHVHTTIRFQGALRRNRCTIM", "length": 203, "header": "tr|E1BR34-1|E1BR34_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RASL10B PE=4 SV=4 CANONICAL=A0A8V1API8-1" }, "locus": { "chromosome": "19", "start_pos": 4874134, "end_pos": 4872219, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071628.1", "url": "https://www.ensembl.org/id/ENSGALT00010071628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044318.1", "url": "https://www.ensembl.org/id/ENSGALP00010044318.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:771592", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771592", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BSI5-1", "protein_name": "small monomeric GTPase", "gene_name": "RASL10B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTPARRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADACCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM", "length": 203 }, "evidence": [ { "id": "A0A8V1API8", "url": "https://omabrowser.org/oma/group/A0A8V1API8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AHZ6-1", "protein_name": "RAS-like, family 10, member B", "gene_name": "Rasl10b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQKGQQDRLRPEKECSQQLWRPQPDLLPKGLSSQEWADACCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM", "length": 235 }, "evidence": [ { "id": "A0A8V1API8", "url": "https://omabrowser.org/oma/group/A0A8V1API8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I8B8-1", "protein_name": "small monomeric GTPase", "gene_name": "Rasl10b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADACCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM", "length": 203 }, "evidence": [ { "id": "A0A8V1API8", "url": "https://omabrowser.org/oma/group/A0A8V1API8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5SSG5-1", "protein_name": "Ras-like protein family member 10B", "gene_name": "Rasl10b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTTRRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADACCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM", "length": 203 }, "evidence": [ { "id": "A0A8V1API8", "url": "https://omabrowser.org/oma/group/A0A8V1API8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96S79-1", "protein_name": "Ras-like protein family member 10B", "gene_name": "RASL10B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM", "length": 203 }, "evidence": [ { "id": "A0A8V1API8", "url": "https://omabrowser.org/oma/group/A0A8V1API8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of systemic arterial blood pressure by atrial natriuretic peptide", "id": "GO:0003050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ], "pmid": "" }, { "name": "positive regulation of peptide hormone secretion", "id": "GO:0090277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1API8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1API8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", 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"https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": 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"activity": "", "evidence": [ { "id": "A0A8V0XC33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC33" } ] } ] }, { "uniprot_ac": "A0A8V0XDD5", "gene_name": "RAB12", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XDD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDD5" } ] } ] }, { "uniprot_ac": "A0A8V0XGK7", "gene_name": "RAB6A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGK7" } ] } ] }, { "uniprot_ac": "A0A8V0XKC3", "gene_name": "RAB18", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XKC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKC3" } ] } ] }, { "uniprot_ac": "A0A8V0XMC5", "gene_name": "RAB10L", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC5" } ] } ] }, { "uniprot_ac": "A0A8V0XNL0", "gene_name": "RABL2A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XNL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNL0" } ] } ] }, { "uniprot_ac": "A0A8V0XVU5", "gene_name": "RASL11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0XVU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVU5" } ] } ] }, { "uniprot_ac": "A0A8V0Y2H3", "gene_name": "RAB10", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y2H3", "database": "UniProtKB", "url": 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"structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APL3" }, { "id": "PS51805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 184, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V1APL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APL3" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 248, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 302, "end_pos": 304 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1APN5-1", "uniprot_ac": "A0A8V1APN5", "uniprot_id": "A0A8V1APN5_CHICK", "mass": { "chemical_mass": 33825.0, "monoisotopic_mass": 33825.0 }, "refseq": { "ac": "NP_001384330", "name": "CMRF35-like molecule 8 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" }, "gene_names": [ { "name": "CD300LG", "type": "recommended", "evidence": [ { "id": "A0A8V1APN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5" } ] }, { "name": "CD300A", "type": "synonym", "evidence": [ { "id": "NP_001384330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] }, { "name": "CD300L-B1", "type": "synonym", "evidence": [ { "id": "NP_001384330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] }, { "name": "CD300L-B2", "type": "synonym", "evidence": [ { "id": "NP_001384330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] }, { "name": "CD300LG", "type": "synonym", "evidence": [ { "id": "NP_001384330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] } ], "protein_names": [ { "name": "CD300 antigen-like family member", "type": "synonym", "evidence": [ { "id": "NP_001384330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] }, { "name": "CD300 molecule like family member g", "type": "synonym", "evidence": [ { "id": "A0A8V1APN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5/entry#names_and_taxonomy" } ] }, { "name": "CD300a molecule", "type": "synonym", "evidence": [ { "id": "NP_001384330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] }, { "name": "CMRF35-like molecule 8 precursor", "type": "synonym", "evidence": [ { "id": "NP_001384330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX271505.4, SRR13267659.289865.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2812696, SAMEA3109052 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000317.1, BX271505.4 and CD729711.1. On Nov 12, 2021 this sequence version replaced XP_015150879.1. Transcript Variant: This variant (2) has the short first intron. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ] }, { "annotation": "SHP-1, but not SHP-2 or the src homology 2 domain containing inositol 5' phosphatase SHIP, was utilized by CD300a for its inhibitory activity. These studies provide new insights into the function of CD300a in tuning T and B cell responses. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001384330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" }, { "database": "PubMed", "id": "22537350", "url": "https://glygen.org/publication/PubMed/22537350" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD300LG", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5", "locus": { "chromosome": "18", "start_pos": 11045652, "end_pos": 11050309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029660", "url": "https://www.ensembl.org/id/ENSGALG00010029660" } ] } } ], "crossref": [ { "id": "A0A8V1APN5", "url": 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"Protein" ] } ], "sequence": { "sequence": "MRLLLLLLCCAALCHPGWAVRGPGTVEGYIGGSLSVSCSYQEGYEMKPKFWCYPGTVRSCSHDIVITSEKEPGVKQGRTSIWDNRTQRVFTVTMKDLTARDHGTYRCGVRTDLLRWDVTDTVRVIVSSGPKSKPSASPSAWTVPPDPISGPTWTSPQQETAKQTARPTSPEDLSEEQLDVVTGILIPCIAVVLFFLALAAAVLVILSWKRKKALAGAPIEMGSTRGTANAEVLQYADISHAGEEQSHLYSNIGAAPVSPQAATEYSEVKKPGQNLEGNTETLNTQVSRIPLEEQEQLYTNVVPRRQRAAQ", "length": 310, "header": "tr|A0A8V1APN5-1|A0A8V1APN5_CHICK Isoform 1 of CD300 molecule like family member g OS=Gallus gallus OX=9031 GN=CD300LG PE=4 SV=1 CANONICAL=A0A8V1APN5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1APN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5/entry#A0A8V1APN5-1", "sequence": { "sequence": "MRLLLLLLCCAALCHPGWAVRGPGTVEGYIGGSLSVSCSYQEGYEMKPKFWCYPGTVRSCSHDIVITSEKEPGVKQGRTSIWDNRTQRVFTVTMKDLTARDHGTYRCGVRTDLLRWDVTDTVRVIVSSGPKSKPSASPSAWTVPPDPISGPTWTSPQQETAKQTARPTSPEDLSEEQLDVVTGILIPCIAVVLFFLALAAAVLVILSWKRKKALAGAPIEMGSTRGTANAEVLQYADISHAGEEQSHLYSNIGAAPVSPQAATEYSEVKKPGQNLEGNTETLNTQVSRIPLEEQEQLYTNVVPRRQRAAQ", "length": 310, "header": "tr|A0A8V1APN5-1|A0A8V1APN5_CHICK Isoform 1 of CD300 molecule like family member g OS=Gallus gallus OX=9031 GN=CD300LG PE=4 SV=1 CANONICAL=A0A8V1APN5-1" }, "locus": { "chromosome": "18", "start_pos": 11049107, "end_pos": 11046199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071712.1", "url": "https://www.ensembl.org/id/ENSGALT00010071712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044402.1", "url": "https://www.ensembl.org/id/ENSGALP00010044402.1" } ] } }, { "isoform_ac": "R4GFS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5/entry#R4GFS8-1", "sequence": { "sequence": "MRLLLLLLCCAALCHPGWAVRGPGTVKGYIGGSLSVSCSYQEGYEMKPKFWCYPGTVRSCSHDIVITSEKEPGAKQGRTSIWDNRTQRVFTVTMKDLTARDHGTYRCGVRTDLLRWDVTDTVRVIVSSGPKSKPSASPSAWTVPPDPISGPTWTSPQQETAKQTARPTSPEDLSEEQLDVVTGILIPCIAVVLFFLALAAAVLVILSWKRKKALAGAPIEMGSTRGTANAEVLQYADISHAGEEQSHLYSNIGAAPVSPQAATEYSEVKKPGQNLEGNTETLNTQVSRIPLEEQEQLYTNVVPRRQRAAQ", "length": 310, "header": "tr|R4GFS8-1|R4GFS8_CHICK Computationally mapped isoform of CD300 molecule like family member g OS=Gallus gallus OX=9031 GN=CD300LG PE=4 SV=1 CANONICAL=A0A8V1APN5-1" }, "locus": { "chromosome": "18", "start_pos": 11050110, "end_pos": 11046199, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071713.1", "url": "https://www.ensembl.org/id/ENSGALT00010071713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044403.1", "url": "https://www.ensembl.org/id/ENSGALP00010044403.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a.", "journal": "BMC immunology", "date": "2012-04-26", "authors": "DeBell Karen E, Simhadri Venkateswara R, Mariano John L, Borrego Francisco", "evidence": [ { "database": "RefSeq", "id": "NP_001384330", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384330" } ], "reference": [ { "type": "PubMed", "id": "22537350", "url": "https://glygen.org/publication/PubMed/22537350" } ] } ], "pathway": [ { "id": "R-GGA-198933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198933", "resource": "Reactome", "description": "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1APN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1APN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1APN5", "database": "UniProtKB", 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annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015151606.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151606" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM57A", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49", "locus": {} } ], "crossref": [ { "id": "A0A8V1AQ49", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AQ49", "database": "AlphaFoldDB", "categories": [] }, { "id": "427836", "url": "https://www.ncbi.nlm.nih.gov/gene/427836", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006634", "database": 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"url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151606", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRTLAVASAFFPGLFAFCVRALRWAAPGWSVKDRVLLSGRLVSTVQATMATVSGLTVVLSCEDVVHDRHWLAVEYIWVLVPYMTYDIYVMYLCHWHKSREKGIAERKHSLTSVRSFLLQERLMVTHHLFILIVLTPVTQHFRGELGDFFVGCIFTAELSTPFVSLGKILMQLKMQDTLLHKVNGILILVTFFLCRILLFPFMYAAYGRQMGIPVYMVPFRIPLHCNIANASLIAPQLYWFTLICRKAVRLYGSSPADKSR", "length": 261, "header": "tr|A0A8V1AQ49-1|A0A8V1AQ49_CHICK Isoform 1 of TLC domain containing 3A OS=Gallus gallus OX=9031 GN=FAM57A PE=4 SV=1 CANONICAL=A0A8V1AQ49-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AQ49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49/entry#A0A8V1AQ49-1", "sequence": { "sequence": "MWRTLAVASAFFPGLFAFCVRALRWAAPGWSVKDRVLLSGRLVSTVQATMATVSGLTVVLSCEDVVHDRHWLAVEYIWVLVPYMTYDIYVMYLCHWHKSREKGIAERKHSLTSVRSFLLQERLMVTHHLFILIVLTPVTQHFRGELGDFFVGCIFTAELSTPFVSLGKILMQLKMQDTLLHKVNGILILVTFFLCRILLFPFMYAAYGRQMGIPVYMVPFRIPLHCNIANASLIAPQLYWFTLICRKAVRLYGSSPADKSR", "length": 261, "header": "tr|A0A8V1AQ49-1|A0A8V1AQ49_CHICK Isoform 1 of TLC domain containing 3A OS=Gallus gallus OX=9031 GN=FAM57A PE=4 SV=1 CANONICAL=A0A8V1AQ49-1" }, "locus": { "chromosome": "19", "start_pos": 7423499, "end_pos": 7420294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072025.1", "url": "https://www.ensembl.org/id/ENSGALT00010072025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044715.1", "url": "https://www.ensembl.org/id/ENSGALP00010044715.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427836", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427836", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZT44-1", "protein_name": "TLC domain containing 3A", "gene_name": "Tlcd3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLTLASGALFFPGLFALSNWALRRLRPGWTDDDCLTVGTRLVSSVQAVLATGAGLTVITSCSNVVSDRHWLATEYVWFLIPYMIYDFYAMYLCEWCRTKDQNLRRVTIIRNFLIENRLMVTHHAVILFFLVPISQKLRGELGDFFVGCIFTAELSTPFVSLGRVLIQLKQQHTLLYKVNGILTVTTFLFCRILLFPFMYWSYGQQKGLSLLQVPFNIPLHCNVANAILISPQLYWFSLLCKKAARLFDTAKAKKDG", "length": 257 }, "evidence": [ { "id": "A0A8V1AQ49", "url": "https://omabrowser.org/oma/group/A0A8V1AQ49/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RHJ6-1", "protein_name": "TLC domain containing 3A", "gene_name": "TLCD3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLLPLAWGSLFFPGLFGLCTWGLRRARPAWTYNDCVMISTRLVSSVQAVLATGSGIIIIRSCSNVVTDRHWLAREYVWFLIPYMVYDSYAMYLCEWYRAGDQSSRQPLTIFRNFLSKNRLMITHHVVILCVLVPVAQRLRGELGDFFVGCIFTAELSTPFVSLGRVLIQLKQQHTLLYKVNGILTLTTFFFCRILLFPFMYWSYGQQQGLSLLQVPSRIPFYCNVANAFLVAPQIYWFSLLCKKAARLFSAPSAKKDG", "length": 258 }, "evidence": [ { "id": "A0A8V1AQ49", "url": "https://omabrowser.org/oma/group/A0A8V1AQ49/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5ND56-1", "protein_name": "TLC domain-containing protein 3A", "gene_name": "Tlcd3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLTLASGALFFPGLFALSIWALHRLRPGWTEDDCLTVGTRLVSSVQAVLATWAGLTVIISCKNVVSDRHWLATEYVWFLIPYMIYDFYAMYCCERCRTKSQKLTRTTIIRNFLIENRLMVTHHTVILLFLVPISQKLRGDLGDFFVGCIFTAELSTPFVSLARIMIQLKQQHTLLYKVNGILTVTTFLFCRILLFPFMYWSYGQQKGLSLLQVPFNIPLHCNMANAVLISPQLYWFSLLCKKAARLFDTAKAKKDG", "length": 257 }, "evidence": [ { "id": "A0A8V1AQ49", "url": "https://omabrowser.org/oma/group/A0A8V1AQ49/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBR7-2", "protein_name": "TLC domain-containing protein 3A", "gene_name": "TLCD3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLTLAGGALFFPGLFALCTWALRRSQPGWSRTDCVMISTRLVSSVHAVLATGSGIVIIRSCDDVITGRHWLAREYVWFLIPYMIYDSYAMYLCEWCRTRDQNRAPSLTLRNFLSRNRLMITHHAVILFVLVPVAQRLRGDLGDFFVGCIFTAELSTPFVSLGRVLIQLKQQHTLLYKVNGILTLATFLSCRILLFPFMYWSYGRQQGLSLLQVPFSIPFYCNVANAFLVAPQIYWFCLLCRKAVRLFDTPQAKKDG", "length": 257 }, "evidence": [ { "id": "A0A8V1AQ49", "url": "https://omabrowser.org/oma/group/A0A8V1AQ49/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ49", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V1AQ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ49" }, { "id": "PS50922", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50922" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLC", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 253, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V1AQ52-1", "uniprot_ac": "A0A8V1AQ52", "uniprot_id": "A0A8V1AQ52_CHICK", "mass": { "chemical_mass": 68179.0, "monoisotopic_mass": 68179.0 }, "refseq": {}, "gene_names": [ { "name": "TRIM65", "type": "recommended", "evidence": [ { "id": "A0A8V1AQ52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52" } ] } ], "protein_names": [ { "name": "Tripartite motif containing 65", "type": "synonym", "evidence": [ { "id": "A0A8V1AQ52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM65", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52", "locus": { "chromosome": "18", "start_pos": 5255163, "end_pos": 5250029, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029773", "url": "https://www.ensembl.org/id/ENSGALG00010029773" } ] } } ], "crossref": [ { "id": "A0A8V1AQ52", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V1AQ52", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AFB7", "url": "https://www.orthodb.org/?gene=A0A8V1AFB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AQ52", "url": "https://www.orthodb.org/?gene=A0A8V1AQ52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V1AFB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AFB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AQ52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQIKYALSDVGHAGLSLLGRAWYTSQMVQSWGSSVEKCSSSGLDLLLLLGIVRREEHNYTGRFPPCCSFPHPQPSMASPVLHKLEDKLLCSICLELFRVPVTLPCGHNFCERCINDHRSKQEQTADGAERGYKCPQCRSSCERQLELKKNVTLSEVVEVARASRVWAESCEVAHVGLCPQHGRPLELYCEDEQRCICCVCSVRQCQRHRRALFGDERSRKQALLERSLEETQREAERMERALRELEERTQSIKDSSERLQAVILSKFTHLEEALAKFQEQMVGKVKQEELVALGHIEKDRNALKDHLEALGQHRDRAQYLLDCSDHQVFLEEFPQLLTPRSREVPPLVEFNAAVVVEPMNEILAATSRLLLEELPASLSPSAPDPIAPGPVQPEETAVKVVSTPAPMCQLRAELLKDHRNLTFDPDTANKYLELSWGQRRAKHGPTAAVGWQERGRCFEPWQVLCAQSYGQGCHYWEVTISSHSVVLGVTYGGLPRHKVRGCKFNIGLDGGSWGLQVREDSYLAWHKGQEEKIQLRLYTKLGVCLDCDHGLLSFYGLGEGVQHIHSFHSVFTEPLFPVFWLCEGRTVTLCHRDCGGPEGELGL", "length": 604, "header": "tr|A0A8V1AQ52-1|A0A8V1AQ52_CHICK Isoform 1 of Tripartite motif containing 65 OS=Gallus gallus OX=9031 GN=TRIM65 PE=4 SV=1 CANONICAL=A0A8V1AQ52-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AFB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52/entry#A0A8V1AFB7-1", "sequence": { "sequence": "MASPVLHKLEDKLLCSICLELFRVPVTLPCGHNFCERCINDHRSKQEQTADGAERGYKCPQCRSSCERQLELKKNVTLSEVVEVARASRVWAESCEVAHVGLCPQHGRPLELYCEDEQRCICCVCSVRQCQRHRRALFGDERSRKQALLERSLEETQREAERMERALRELEERTQSIKDSSERLQAVILSKFTHLEEALAKFQEQMVGKVKQEELVALGHIEKDRNALKDHLEALGQHRDRAQYLLDCSDHQVFLEEFPQLLTPRSREVPPLVEFNAAVVVEPMNEILAATSRLLLEELPASLSPSAPDPIAPDHRNLTFDPDTANKYLELSWGQRRAKHGPTAAVGWQERGRCFEPWQVLCAQSYGQGCHYWEVTISSHSVVLGVTYGGLPRHKVRGCKFNIGLDGGSWGLQVREDSYLAWHKGQEEKIQLRLYTKLGVCLDCDHGLLSFYGLGEGVQHIHSFHSVFTEPLFPVFWLCEGRTVTLCHRDCGGPEGELGL", "length": 500, "header": "tr|A0A8V1AFB7-1|A0A8V1AFB7_CHICK Computationally mapped isoform of Tripartite motif containing 65 OS=Gallus gallus OX=9031 GN=TRIM65 PE=4 SV=1 CANONICAL=A0A8V1AQ52-1" }, "locus": { "chromosome": "18", "start_pos": 5254800, "end_pos": 5251870, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072030.1", "url": "https://www.ensembl.org/id/ENSGALT00010072030.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044720.1", "url": "https://www.ensembl.org/id/ENSGALP00010044720.1" } ] } }, { "isoform_ac": "A0A8V1AQ52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52/entry#A0A8V1AQ52-1", "sequence": { "sequence": "MNQIKYALSDVGHAGLSLLGRAWYTSQMVQSWGSSVEKCSSSGLDLLLLLGIVRREEHNYTGRFPPCCSFPHPQPSMASPVLHKLEDKLLCSICLELFRVPVTLPCGHNFCERCINDHRSKQEQTADGAERGYKCPQCRSSCERQLELKKNVTLSEVVEVARASRVWAESCEVAHVGLCPQHGRPLELYCEDEQRCICCVCSVRQCQRHRRALFGDERSRKQALLERSLEETQREAERMERALRELEERTQSIKDSSERLQAVILSKFTHLEEALAKFQEQMVGKVKQEELVALGHIEKDRNALKDHLEALGQHRDRAQYLLDCSDHQVFLEEFPQLLTPRSREVPPLVEFNAAVVVEPMNEILAATSRLLLEELPASLSPSAPDPIAPGPVQPEETAVKVVSTPAPMCQLRAELLKDHRNLTFDPDTANKYLELSWGQRRAKHGPTAAVGWQERGRCFEPWQVLCAQSYGQGCHYWEVTISSHSVVLGVTYGGLPRHKVRGCKFNIGLDGGSWGLQVREDSYLAWHKGQEEKIQLRLYTKLGVCLDCDHGLLSFYGLGEGVQHIHSFHSVFTEPLFPVFWLCEGRTVTLCHRDCGGPEGELGL", "length": 604, "header": "tr|A0A8V1AQ52-1|A0A8V1AQ52_CHICK Isoform 1 of Tripartite motif containing 65 OS=Gallus gallus OX=9031 GN=TRIM65 PE=4 SV=1 CANONICAL=A0A8V1AQ52-1" }, "locus": { "chromosome": "18", "start_pos": 5254800, "end_pos": 5250228, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010072031.1", "url": "https://www.ensembl.org/id/ENSGALT00010072031.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044721.1", "url": "https://www.ensembl.org/id/ENSGALP00010044721.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1AQ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AQ52" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": 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This record is derived from a genomic sequence (NC_052549.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001231907.1. 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"MAEAGTGFLEQLKSCIVWSWTYLWTLWFFIMLFLVYILRVPLKINDNLTTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNSAPSAANAANGEADSSRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDTDHLRPADAIMQKAWRERNPQARISAAHEALELNECATAYILLAEEEATTIVEAEKLFKQALKAGEGCYRRSQQLQHHGAQYEAQHRRDTNVLVYIKRRLAMCARKLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAFLSTLFAPLNFVMEKVESILPSSLWHQLTRI", "length": 554, "header": "sp|A0M8U1-1|ST7_CHICK Isoform 1 of Suppressor of tumorigenicity 7 protein homolog OS=Gallus gallus OX=9031 GN=ST7 PE=3 SV=1 CANONICAL=A0M8U1-1" }, "isoforms": [ { "isoform_ac": "A0M8U1-1", "url": "https://www.uniprot.org/uniprotkb/A0M8U1/entry#A0M8U1-1", "sequence": { "sequence": 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"https://glygen.org/publication/PubMed/12917688" } ] } ], "pathway": [ { "id": "gga:417770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417770", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0M8U1", "url": "https://www.uniprot.org/uniprotkb/A0M8U1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-A0M8U1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 554, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-A0M8U1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/A0M8U1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5HUK4-1", "uniprot_ac": "A5HUK4", "uniprot_id": "A5HUK4_CHICK", "mass": { "chemical_mass": 56346.0, "monoisotopic_mass": 56346.0 }, "refseq": { "ac": "NP_001025842", "name": "tripartite motif-containing 27", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025842" }, "gene_names": [ { "name": "TRIM27.1", "type": "recommended", "evidence": [ { "id": "A5HUK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5HUK4" } ] }, { "name": "TRIM27.1", "type": "synonym", "evidence": [ { "id": "NP_001025842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025842" } ] }, { "name": "TRIM27", "type": "synonym", "evidence": [ { "id": "NP_001025842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025842" } ] } ], "protein_names": [ { "name": "Tripartite motif containing 27.1, MHCB region", "type": "synonym", "evidence": [ { "id": "A5HUK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5HUK4/entry#names_and_taxonomy" } ] }, { "name": "Tripartite motif protein 27", "type": "synonym", "evidence": [ { "id": "NP_001025842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025842" } ] }, { "name": "tripartite motif containing 27.1, MHC-B region", "type": "synonym", "evidence": [ { "id": "NP_001025842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025842" } ] }, { "name": "tripartite motif containing 27.1", "type": "synonym", "evidence": [ { "id": "NP_001025842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025842" } ] }, { "name": "tripartite motif-containing 27", "type": "synonym", "evidence": [ { "id": "NP_001025842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025842" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.112020.1, SRR13267659.187097.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140853 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000283.1. On Apr 29, 2011 this sequence version replaced NP_001025842.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. 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"header": "tr|D5GR58-1|D5GR58_CHICK Isoform 1 of Ovodefensin subfamily A, member 3 OS=Gallus gallus OX=9031 GN=OvoDA3 PE=4 SV=1 CANONICAL=D5GR58-1" }, "locus": { "chromosome": "3", "start_pos": 106924833, "end_pos": 106924488, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026881.1", "url": "https://www.ensembl.org/id/ENSGALT00010026881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015315.1", "url": "https://www.ensembl.org/id/ENSGALP00010015315.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422031", "resource": "KEGG Pathway" }, { "id": "gga:422032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422032", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQ46-1", "uniprot_ac": "E1BQ46", "uniprot_id": "E1BQ46_CHICK", "mass": { "chemical_mass": 70030.0, "monoisotopic_mass": 70030.0 }, "refseq": {}, "gene_names": [ { "name": "ZBTB44", "type": "recommended", "evidence": [ { "id": "E1BQ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ46" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 44", "type": "recommended", "evidence": [ { "id": "E1BQ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ46/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQ46", "url": "https://www.uniprot.org/uniprotkb/E1BQ46" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB44", "url": "https://www.uniprot.org/uniprotkb/E1BQ46", "locus": { "chromosome": "24", "start_pos": 1651284, "end_pos": 1708555, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023408", "url": "https://www.ensembl.org/id/ENSGALG00010023408" } ] } } ], "crossref": [ { "id": "E1BQ46", "url": "https://alphafold.ebi.ac.uk/entry/E1BQ46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001341", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001341", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101751641", "url": "https://www.ncbi.nlm.nih.gov/gene/101751641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMT3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0L5", "url": "https://www.orthodb.org/?gene=A0A8V1A0L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQ46", "url": "https://www.orthodb.org/?gene=E1BQ46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24383:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24383:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZMT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0L5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0L5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ46", "url": "https://www.uniprot.org/uniprotkb/E1BQ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ46-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKERWQKGEKMGVKTFTHNSPAHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRSKLVGQAEDESKSVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNTPNSQQEKVLDAGQESNANCNFTSRDGSLSPVSSECSVVERAIPVCRESRRKRKSYIVMSPESPVKCNTQTSSPQVLNPSASYPESRNQPVDSSLAFPWTFPFGIDRRLQSEKVKQVENSRTLEMPGPSESNRRIADYVTCESTKANSPLVIEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSMDEGVTEGLPTLQSTSGANAHADDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEGKRCFRCQICSATFTSFGEYKHHMRVSRHIIRKPRIYECKTCGAMFTNSGNLIVHLRSLNHEASELANYFQSSDFLVPDYLNQEQEETLGQYELGEHGFESNSSVQMPVISQVSSTQNCESTFPLGSLGGLAEKEEDVPEQPKTNATAEATAGDPPKPELSSITIE", "length": 627, "header": "tr|E1BQ46-1|E1BQ46_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 44 OS=Gallus gallus OX=9031 GN=ZBTB44 PE=4 SV=3 CANONICAL=E1BQ46-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMT3-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ46/entry#A0A8V0ZMT3-1", "sequence": { "sequence": "MWKERWQKGEKMGVKTFTHNSPAHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRSKLVGQAEDESKSVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNTPNSQQEKVLDAGQESNANCNFTSRDGSLSPVSSECSVVERAIPVCRESRRKRKSYIVMSPESPVKCNTQTSSPQVLNPSASYPESRNQPVDSSLAFPWTFPFGIDRRLQSEKVKQVENSRTLEMPGPSESNRRIADYVTCESTKANSPLVIEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSMDEGVTEGLPTLQSTSGANAHADDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEGKRCFRCQICSATFTSFGEYKHHMRVSRHIIRKPRIYECKTCGAMFTNSGNLIVHLRSLNHEASELANYFQSRWMLEALAGTSLHQIQEIELLLSGIYGWKRAGKLLWKKKLQCKMNRFQRTCVNCAGAPRNKGMARTAASHAAEILGVGGR", "length": 613, "header": "tr|A0A8V0ZMT3-1|A0A8V0ZMT3_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 44 OS=Gallus gallus OX=9031 GN=ZBTB44 PE=4 SV=1 CANONICAL=E1BQ46-1" }, "locus": { "chromosome": "24", "start_pos": 1691013, "end_pos": 1651448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057059.1", "url": "https://www.ensembl.org/id/ENSGALT00010057059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034706.1", "url": "https://www.ensembl.org/id/ENSGALP00010034706.1" } ] } }, { "isoform_ac": "A0A8V1A0L5-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ46/entry#A0A8V1A0L5-1", "sequence": { "sequence": "MWKERWQKGEKMGVKTFTHNSPAHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRSKLVGQAEDESKSVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNTPNSQQEKVLDAGQESNANCNFTSRDGSLSPVSSECSVVERAIPVCRESRRKRKSYIVMSPESPVKCNTQTSSPQVLNPSASYPESRNQPVDSSLAFPWTFPFGIDRRLQSEKVKQVENSRTLEMPGPSESNRRIADYVTCESTKANSPLVIEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSMDEGVTEGLPTLQSTSGANAHADDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEGKRCFRCQICSATFTSFGEYKHHMRVSRHIIRKPRIYECKTCGAMFTNSGNLIVHLRSLNHEASELANYFQSRWMLEALAGTSLHQIQEIELLLSGIYGWKRAGKLLWKVSNAAER", "length": 577, "header": "tr|A0A8V1A0L5-1|A0A8V1A0L5_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 44 OS=Gallus gallus OX=9031 GN=ZBTB44 PE=4 SV=1 CANONICAL=E1BQ46-1" }, "locus": { "chromosome": "24", "start_pos": 1691013, "end_pos": 1654409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057053.1", "url": "https://www.ensembl.org/id/ENSGALT00010057053.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034702.1", "url": "https://www.ensembl.org/id/ENSGALP00010034702.1" } ] } }, { "isoform_ac": "E1BQ46-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ46/entry#E1BQ46-1", "sequence": { "sequence": "MWKERWQKGEKMGVKTFTHNSPAHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRSKLVGQAEDESKSVLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILWNTPNSQQEKVLDAGQESNANCNFTSRDGSLSPVSSECSVVERAIPVCRESRRKRKSYIVMSPESPVKCNTQTSSPQVLNPSASYPESRNQPVDSSLAFPWTFPFGIDRRLQSEKVKQVENSRTLEMPGPSESNRRIADYVTCESTKANSPLVIEEDVRVKVERLSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSMDEGVTEGLPTLQSTSGANAHADDDDRLENVQYPYQLYIAPSTSSTERPSPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRLKHEGKRCFRCQICSATFTSFGEYKHHMRVSRHIIRKPRIYECKTCGAMFTNSGNLIVHLRSLNHEASELANYFQSSDFLVPDYLNQEQEETLGQYELGEHGFESNSSVQMPVISQVSSTQNCESTFPLGSLGGLAEKEEDVPEQPKTNATAEATAGDPPKPELSSITIE", "length": 627, "header": "tr|E1BQ46-1|E1BQ46_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 44 OS=Gallus gallus OX=9031 GN=ZBTB44 PE=4 SV=3 CANONICAL=E1BQ46-1" }, "locus": { "chromosome": "24", "start_pos": 1691013, "end_pos": 1677290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057049.1", "url": "https://www.ensembl.org/id/ENSGALT00010057049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034700.1", "url": "https://www.ensembl.org/id/ENSGALP00010034700.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BQ46", "url": "https://www.uniprot.org/uniprotkb/E1BQ46" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BQ46", "url": "https://www.uniprot.org/uniprotkb/E1BQ46" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BQ46", "url": "https://www.uniprot.org/uniprotkb/E1BQ46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BQ46", "url": "https://www.uniprot.org/uniprotkb/E1BQ46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQ46-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 627, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQ46-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQ46" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 606, "end_pos": 608 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQB4-1", "uniprot_ac": "E1BQB4", "uniprot_id": "E1BQB4_CHICK", "mass": { "chemical_mass": 79611.0, "monoisotopic_mass": 79611.0 }, "refseq": { "ac": "XP_004940478", "name": "lebercilin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940478" }, "gene_names": [ { "name": "LCA5", "type": "recommended", "evidence": [ { "id": "E1BQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQB4" } ] }, { "name": "LCA5", "type": "synonym", "evidence": [ { "id": "XP_004940478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940478" } ] } ], "protein_names": [ { "name": "Lebercilin LCA5", "type": "synonym", "evidence": [ { "id": "E1BQB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQB4/entry#names_and_taxonomy" } ] }, { "name": "lebercilin", "type": "synonym", "evidence": [ { "id": "XP_004940478", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940478" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940478" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQB4", "url": "https://www.uniprot.org/uniprotkb/E1BQB4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LCA5", "url": "https://www.uniprot.org/uniprotkb/E1BQB4", "locus": { "chromosome": "3", "start_pos": 79113736, "end_pos": 79097519, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003778", "url": "https://www.ensembl.org/id/ENSGALG00010003778" } ] } } ], "crossref": [ { "id": "E1BQB4", "url": "https://alphafold.ebi.ac.uk/entry/E1BQB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015878", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015878", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421852", "url": "https://www.ncbi.nlm.nih.gov/gene/421852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421852", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421852", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQIQNID", "url": "https://omabrowser.org/oma/group/YQIQNID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BQB4", "url": "https://www.orthodb.org/?gene=E1BQB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16650", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16650", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16650:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16650:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940478", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940478", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BQB4", "url": "https://www.uniprot.org/uniprotkb/E1BQB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQB4-1", "url": "https://www.uniprot.org/uniprotkb/E1BQB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGERVRSPDSEHDRRSDEDRNSDSYYSDEENASHSSDRSPTLSYPSTSHEKQDHKTRASDSLVHYQATKKLGSKYAPSKRGTRWGFRSQSLTRDSPAKDIDLVTKRVLSARLLKINELRNELTELHIKLDELQKENRALKRLQHRQEKALNKFEDTENEISQLIAQHNNEIRILRERLRKSQERERATERRLKDSEDELYRTKTVLQKLKKLSADKHLAERDDLAKKLAYAESRLEESEKRIKDLEKNLELSGSSFQRELQLKKKKVLEAQDKNRALQEELLQLNQKLKEKERELDAKNIYANRMLKVSPRKGMAVIQRKKANNQNINKGAQLTKGVQTGGYFSPVELPPESELVCGDPVDKKERILSRIEKEPQNKEWKEQADLLKQEQDREKEEKLKRVQELQTSEERFQKLRDEWEKEEYDKMKKESSFLLDKEDKTKMETETHKPEIETESTEMLEERRKSEFLLAKMNEIDRETQNVMNMKLASQTSFINTLRKSDSPEKKERNGQFFEIPGKVTNGVPQEDSQEDATRAHGQKQRNLRTVDLSNELTFGSYVPSFGKASGRPSWLNPKGDSLEENMKENADFHSRKEKKSNLMEQLFGSSASTTLLPKSKDTKSFDIDWESSDTLLDKNSKIKVREDNDLSSEGRNLNRHRLQHAGSKPAFKTLGSLEDEIEEVVLQ", "length": 683, "header": "tr|E1BQB4-1|E1BQB4_CHICK Isoform 1 of Lebercilin LCA5 OS=Gallus gallus OX=9031 GN=LCA5 PE=3 SV=2 CANONICAL=E1BQB4-1" }, "isoforms": [ { "isoform_ac": "E1BQB4-1", "url": "https://www.uniprot.org/uniprotkb/E1BQB4/entry#E1BQB4-1", "sequence": { "sequence": "MGERVRSPDSEHDRRSDEDRNSDSYYSDEENASHSSDRSPTLSYPSTSHEKQDHKTRASDSLVHYQATKKLGSKYAPSKRGTRWGFRSQSLTRDSPAKDIDLVTKRVLSARLLKINELRNELTELHIKLDELQKENRALKRLQHRQEKALNKFEDTENEISQLIAQHNNEIRILRERLRKSQERERATERRLKDSEDELYRTKTVLQKLKKLSADKHLAERDDLAKKLAYAESRLEESEKRIKDLEKNLELSGSSFQRELQLKKKKVLEAQDKNRALQEELLQLNQKLKEKERELDAKNIYANRMLKVSPRKGMAVIQRKKANNQNINKGAQLTKGVQTGGYFSPVELPPESELVCGDPVDKKERILSRIEKEPQNKEWKEQADLLKQEQDREKEEKLKRVQELQTSEERFQKLRDEWEKEEYDKMKKESSFLLDKEDKTKMETETHKPEIETESTEMLEERRKSEFLLAKMNEIDRETQNVMNMKLASQTSFINTLRKSDSPEKKERNGQFFEIPGKVTNGVPQEDSQEDATRAHGQKQRNLRTVDLSNELTFGSYVPSFGKASGRPSWLNPKGDSLEENMKENADFHSRKEKKSNLMEQLFGSSASTTLLPKSKDTKSFDIDWESSDTLLDKNSKIKVREDNDLSSEGRNLNRHRLQHAGSKPAFKTLGSLEDEIEEVVLQ", "length": 683, "header": "tr|E1BQB4-1|E1BQB4_CHICK Isoform 1 of Lebercilin LCA5 OS=Gallus gallus OX=9031 GN=LCA5 PE=3 SV=2 CANONICAL=E1BQB4-1" }, "locus": { "chromosome": "3", "start_pos": 79113684, "end_pos": 79102185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008736.1", "url": "https://www.ensembl.org/id/ENSGALT00010008736.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005112.1", "url": "https://www.ensembl.org/id/ENSGALP00010005112.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421852", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BBH3-1", "protein_name": "Lebercilin LCA5", "gene_name": "LCA5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEREGSPDTDRESKAGRHCYSDCSSDFGGTPRSSRRSSLVHPSSPTSIKGKNSKKQISDSQVHHQVPRKPSPKGPPHRKGVQVGFRSQSLNRESLRKDTDLVTKRVLSARLLKINELQNEVTELQVKLAELLKENKALKRLQYRQEKALNKFEDTENEISQLIARHNNEITALKERLRKSQEKERATEKRVKDTEDELFRTKFSLQKLKKISEARHLPERDDLAKKLVSAELKLDDTERRIKELSRNLELSTNSFQRQLLAERKRAYEAYDENKVLQKELQQLYHKLKEKERELDIKNIYSNRLPKSSPKKEKELTSRKNAACQSDITNQCTKGVQTSEDLELKEYPLTPQTVMCYENKWEEPERLSLDLKSQKGNDHEEAGILNPVVEREDKFVKDQGLRIVKQEVEKLEDEWEREELAKKQKEKTALLEREQKPVLETGRYQMEMYQIQNMDKLEEEEEERLKKEMLLAKLNEINRELQDSQNLKYPSLPLLPHLESKLHSRERNSRTYMFSESSETSNGHHLQDIGLLAAKGDGPNPGDISSPASADELAFGSYVPSFAKTSGKSNPLSQKSGLLDFQRNNIEKVSKDSVDLITRKEKKANLMEQLFGTSGLSSISSKSSDPNSLAAPKGDLDPPDFLPGDKSSRGREHDDDDDSFFLSEGRSFNSNRHRLKHANHKPAVKAVDSVEDEIEEVALR", "length": 700 }, "evidence": [ { "id": "E1BQB4", "url": "https://omabrowser.org/oma/group/E1BQB4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9QG33-1", "protein_name": "Lebercilin", "gene_name": "lca5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLHEDNQESEHSRLSHHNERKILESLRSGKQENNGKDMGNSAGDHAQSRTRETAGDPGRNGFSDGERSSGSFYSDDYENASHSDRSLSPSASPSPPRRGRSRRVSSSPLHKTGVHKGASRRILSHSHHPQQRAGAIRSQSLSKDAPSKEVDQVTKRMLSARLLKINELKNALSELRLHADELQRENRLLRQLQLRQEKALHRYNDTDSEISQLLARHNNETHVLRERLRRSQENQRTAERSLRERDAQLQRCRSQMQKLQQLADDQNLGEREELSRKLIGTQSRLQDSEHRVKELEKNMELSSGSFQRQLANERRKTHDAQQEVKALQEEVERLCTKLKEKERELDARNIYANRMHKASSRKEAENGSKRKGFNITSTKAVQTEDRTSSLDFPSPPPALTNNLPPDDQTDDYLSLKDQQSREHRTRESKEWKIQEFWREREKERHMESAREQEKEKETLHERERQTELLKDVERQRLDQDLSSNEKNFKGNRVGLNREEEDRRIGMSVSQKEEEIQKQRELEEEQQKVRNREIQDYNQERVEEERQRKEQLLAKMREIDIQTQGQDSDFFSDDTGSVRSPPRLSEQRNHNGFFKLTEPDENINTFSSGRRGGSLRAQAPNEDLDLAFGSYAPSFGKSTPRAGLGTRNAQNHSPRELDEGLDLGGLVKERKSNLMQQLFGATATPPPSDPSSKMEILSPPLTTQFSGRRRDTDTPNELNISSLPNNRSTLQVSESRPAVRAITSFDDDIEELTL", "length": 754 }, "evidence": [ { "id": "E1BQB4", "url": "https://omabrowser.org/oma/group/E1BQB4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MF34-1", "protein_name": "Lebercilin LCA5", "gene_name": "LCA5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGERDRSPATDREGKTSRSHYCSSDFGTTPQSSGRSSLVHPSPPASIKGKHDKKQASDSQVHHHAPRKPSPKCPPNRKGVRAGFRSQSLSRQPFPKDPDLVTKQVLSARLLKINELQNEVTELQVKLAELLKENKALKRLQYRQEKALNKFEDTENEISQLIARHNNEITALKDRLRKSQEKDRANEKRAKETEGELLKTKISLQKLKKISEAKHLPERVDLAKKLASAELKLDDTERRIKDLSRNLELSTNSYQRQLLAERKRACEARDENKLLQKELQGLKDKLKEKERELDIKNRYSNRLPKISPKKEKEFTSTINAACQSDFTNQCTKGVQTNEDFKLEEYPITPQTVMCYENKREEPERLSLDMESQERDNLGEAGILNPTVEREDKFAKGQGLRVVKQNVEKLENGWEKELAKKPKEKKSLLEREGKPVEMYQVQKIDKLEEERLKKEMLPAKLNEINREQDSQNVKYPSLPPLPDLKRKLRSPERNPRTHMSSGSSERLFNGHHLQDLNLSTTKGDGQNPGHTRSAASPVELVFGSYVPSFAKTPARSNPVSQKSDLLGFSGNNTEKFSKDGTDSISRQERKANLMELLFGTSGGSSLSSKNSDPNSLAATKDGDPLDFLPGDKSSWGRENRDDDDSLLSEERSFNPSRHRLRRANSKPAVKVVDSVEDEIEEVVLR", "length": 684 }, "evidence": [ { "id": "E1BQB4", "url": "https://omabrowser.org/oma/group/E1BQB4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H729-1", "protein_name": "Lebercilin", "gene_name": "Lca5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGERARSTDADQERKSGKHHSSHYSSDFGSTPQSSVYSSPVHQPKCPSTKEKNPKRHLSGHQVYHQAVRKVSPKAGPSKKGSRIGFRSQSLNREPLRKDPDIITKRILSARLLKINELQNEVSELQVKLAQLLKENKALKSLQFRQEKALTKFEDAENEISHLIQRHNNEITALKERLRKSQEKERVTEKRVKDTEGELFRTKFSLQKLKKISEARHLPERDDLAKKLVTAELKLDDTERKIKELSKNLELSTNSFQRQLLAERKRAFEAYDENKLLQKELQRLYHKLKEKERELDIKNIYANRLPKSSAKKDKEVIQRKNVSCQSDFTDLCTKGVQTTEDLELEEFSFASQTVLCYENKWDEPDYFSSYLEYQEQSERETTTIPNSSSEREEIFSEDQEKCSSKQESGKSEKESEKEELDKAQSNKETSLVVRTEKPALEAGKFHAQTHQTQNAKQREDEAERLKTEMLLAKLNEINRELQDPQNLKRPPLPLLPNFESKQHSPDRSSKPSTHSESSDRSSSGQHSSDVSSSTARGEGRSPAPIRSPGTTQSPVPPDEFSFGSYVPSFAKTSGKSNTLSQKSSFLDFQSSSLESLSKDSTDSISRKEKKASLMEELFGTGSSTSTSSTTISSSKSGDPHFLTAGRGDLDPLNFPSGDKCGRVREPDDEDEDFFLGEGRSFNPNRQRLKHASNKPSVTAVDSVDEDIEEVTLR", "length": 713 }, "evidence": [ { "id": "E1BQB4", "url": "https://omabrowser.org/oma/group/E1BQB4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q86VQ0-1", "protein_name": "Lebercilin", "gene_name": "LCA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGERAGSPGTDQERKAGKHHYSYLSDFETPQSSGRSSLVSSSPASVRRKNPKRQTSDGQVHHQAPRKPSPKGLPNRKGVRVGFRSQSLNREPLRKDTDLVTKRILSARLLKINELQNEVSELQVKLAELLKENKSLKRLQYRQEKALNKFEDAENEISQLIFRHNNEITALKERLRKSQEKERATEKRVKDTESELFRTKFSLQKLKEISEARHLPERDDLAKKLVSAELKLDDTERRIKELSKNLELSTNSFQRQLLAERKRAYEAHDENKVLQKEVQRLYHKLKEKERELDIKNIYSNRLPKSSPNKEKELALRKNAACQSDFADLCTKGVQTMEDFKPEEYPLTPETIMCYENKWEEPGHLTLDLQSQKQDRHGEAGILNPIMEREEKFVTDEELHVVKQEVEKLEDEWEREELDKKQKEKASLLEREEKPEWETGRYQLGMYPIQNMDKLQGEEEERLKREMLLAKLNEIDRELQDSRNLKYPVLPLLPDFESKLHSPERSPKTYRFSESSERLFNGHHLQDISFSTPKGEGQNSGNVRSPASPNEFAFGSYVPSFAKTSERSNPFSQKSSFLDFQRNSMEKLSKDGVDLITRKEKKANLMEQLFGASGSSTISSKSSDPNSVASSKGDIDPLNFLPGNKGSRDQEHDEDEGFFLSEGRSFNPNRHRLKHADDKPAVKAADSVEDEIEEVALR", "length": 697 }, "evidence": [ { "id": "E1BQB4", "url": "https://omabrowser.org/oma/group/E1BQB4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "E1BQB4", "url": "https://www.uniprot.org/uniprotkb/E1BQB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "E1BQB4", "url": "https://www.uniprot.org/uniprotkb/E1BQB4" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "E1BQB4", "url": "https://www.uniprot.org/uniprotkb/E1BQB4" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "E1BQB4", "url": "https://www.uniprot.org/uniprotkb/E1BQB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "E1BQB4", "url": "https://www.uniprot.org/uniprotkb/E1BQB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQB4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 683, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQB4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQB4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQL6-1", "uniprot_ac": "E1BQL6", "uniprot_id": "E1BQL6_CHICK", "mass": { "chemical_mass": 69994.0, "monoisotopic_mass": 69994.0 }, "refseq": { "ac": "XP_003642836", "name": "zinc finger protein 652 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642836" }, "gene_names": [ { "name": "ZNF652", "type": "recommended", "evidence": [ { "id": "E1BQL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ] }, { "name": "ZNF652", "type": "synonym", "evidence": [ { "id": "XP_003642836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642836" } ] } ], "protein_names": [ { "name": "Zinc finger protein 652", "type": "synonym", "evidence": [ { "id": "E1BQL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQL6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 652 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003642836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642836" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642836" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF652", "url": "https://www.uniprot.org/uniprotkb/E1BQL6", "locus": { "chromosome": "27", "start_pos": 3226519, "end_pos": 3202764, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024430", "url": "https://www.ensembl.org/id/ENSGALG00010024430" } ] } } ], "crossref": [ { "id": "E1BQL6", "url": "https://alphafold.ebi.ac.uk/entry/E1BQL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001279", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001279", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419987", "url": "https://www.ncbi.nlm.nih.gov/gene/419987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419987", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VESCAVH", "url": "https://omabrowser.org/oma/group/VESCAVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BQL6", "url": "https://www.orthodb.org/?gene=E1BQL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003642836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQL6-1", "url": "https://www.uniprot.org/uniprotkb/E1BQL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQTANSCQQLVENCAVHVAGMAQEDSRRGQVPPTFYHGASQELDLSTKVYKRESGSPYPVLVDSKMSKPHLHEREEQPYFRENRSVGEVRAVKEDRENSDDSEEEEEEEDEVTYKREQIIVEVNLNNQTLNVSKGEKGVPSQSKETAVLKTSSEEEEGDSGEEATEDSNDYEENERQKKKEKRVEKVSVAQRRTRRAASAAAATTSPSPRTTRGRRKSVEPPKRKKKAAKEPKAPVQKSKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVSSAVQIPLSTTSATTVPAVVNTPTAPTPPINLNPVSTLPPRPIPHPYSHLHLHPHPHHPHHLPVPPVPHLPPPPALFKSEPLNHRGQSEDSFLRHLAEKNSSAQHH", "length": 609, "header": "tr|E1BQL6-1|E1BQL6_CHICK Isoform 1 of Zinc finger protein 652 OS=Gallus gallus OX=9031 GN=ZNF652 PE=3 SV=3 CANONICAL=E1BQL6-1" }, "isoforms": [ { "isoform_ac": "E1BQL6-1", "url": "https://www.uniprot.org/uniprotkb/E1BQL6/entry#E1BQL6-1", "sequence": { "sequence": "MSQTANSCQQLVENCAVHVAGMAQEDSRRGQVPPTFYHGASQELDLSTKVYKRESGSPYPVLVDSKMSKPHLHEREEQPYFRENRSVGEVRAVKEDRENSDDSEEEEEEEDEVTYKREQIIVEVNLNNQTLNVSKGEKGVPSQSKETAVLKTSSEEEEGDSGEEATEDSNDYEENERQKKKEKRVEKVSVAQRRTRRAASAAAATTSPSPRTTRGRRKSVEPPKRKKKAAKEPKAPVQKSKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVSSAVQIPLSTTSATTVPAVVNTPTAPTPPINLNPVSTLPPRPIPHPYSHLHLHPHPHHPHHLPVPPVPHLPPPPALFKSEPLNHRGQSEDSFLRHLAEKNSSAQHH", "length": 609, "header": "tr|E1BQL6-1|E1BQL6_CHICK Isoform 1 of Zinc finger protein 652 OS=Gallus gallus OX=9031 GN=ZNF652 PE=3 SV=3 CANONICAL=E1BQL6-1" }, "locus": { "chromosome": "27", "start_pos": 3224438, "end_pos": 3217252, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059604.1", "url": "https://www.ensembl.org/id/ENSGALT00010059604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036403.1", "url": "https://www.ensembl.org/id/ENSGALP00010036403.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 530, "start_aa": "Thr", "end_pos": 530, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr530", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419987", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1L1J6-1", "protein_name": "Zinc finger protein 652", "gene_name": "Znf652", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYTASPCQELVEPCAVHAEGMAQEESHRSQAPPTFYHGASQELDLSTKVYKRESGSPYSVLADSKMSKPHLHETEEQPYFREPRAVSDVHTVKEDRENSDDTEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEETEEDATDNSSDYGENGRQKKKEKQVEKVRVTQRRTRRAASVAAATTSPTPRTTRGRRKSAELPKRKKRAAKEPKAPVQKAKCDEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFACEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLASAPAAPAPAVANTPTSPAPAVSMNPVGSALPSRPVPHPFSHLHIHTHPHHSHHLPIPPVPHLPPPPALFKSEPLNHRSQSEDTFLRHLAEKNSPAQAQHH", "length": 608 }, "evidence": [ { "id": "E1BQL6", "url": "https://omabrowser.org/oma/group/E1BQL6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N440-1", "protein_name": "Zinc finger protein 652", "gene_name": "ZNF652", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSHTASSCQELAENRAVHGAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHGVKEDRENSDDTEEEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENERQKKKEKTVEKVSVTQRRTRRAASVAAAATSPTPRATRGRRKSVEPPKRKKRATKEPKAAVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTTSPATPVPSAVNTPTTPAPPVSMNPVGTLPPRPIPHPFSHLHIHAHPHHPHHLPIPPVPHLPPPPALFKSEPLNNRGQGEDTFLRHLAEKNSAAQHH", "length": 608 }, "evidence": [ { "id": "E1BQL6", "url": "https://omabrowser.org/oma/group/E1BQL6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RWF4-1", "protein_name": "Zinc finger protein 652", "gene_name": "ZNF652", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSHTTSSCQELVENCAVHVAGMAQEESRRGQVPSTFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPFFRETRAVSDVHAVKEDRENSDDTEEEEEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENERQKKKEKIVEKVSVTQRRTRRAASVAAAATSPTPRATRGRRKSVEPPKRKKRAAKEPKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTSAPATPVPSVVNTPATPAPPITMNPVSTLPPRPIPHPFSHLHIHAHPHHPHHLPIPPVPHLPPLQLSLRASP", "length": 585 }, "evidence": [ { "id": "E1BQL6", "url": "https://omabrowser.org/oma/group/E1BQL6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HJP5-1", "protein_name": "Zinc finger protein 652", "gene_name": "Znf652", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSYPASPCQELAENCAVHATGMAQEESRRSQAPPAFYRGASQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHTVKEDRENSDDTEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEGEEESEEATDDSNDYGENERQKKKEKRAEKVRVTQRRTRRTASVAAAATSPTPRTTRGRRKSAELPKRKKRATKEPKAAVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFACEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLASAPAAPAPAVASTPTSPAPAVSMNPVGGALPSRPVPHPFSHLHIPTHPHHAHHLPIPPVPHLPPPPALFKSEPLNHRGQSEDTFLRHLAEKNNTAQAQHH", "length": 607 }, "evidence": [ { "id": "E1BQL6", "url": "https://omabrowser.org/oma/group/E1BQL6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5DU09-1", "protein_name": "Zinc finger protein 652", "gene_name": "Znf652", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYTASPCPELVEPCAVHAEGMAQEESHRSQAPPTFYHGASQELDLSTKVYKRESGSPYSVLADTKMSKPHLHETEEQPYFREPRAVSDVHTVKEDRENSDDTEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEDEEETEEEATDNSSDYGENGRQKKKEKQVERVRVTQRRTRRAASAAAATTSPAPRTTRGRRKSAELPKRKKRATKEAKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFACEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLASAPAAPAPAVANTPTSPAPAVSMSPVGAVLPSRPVPHPFSHLHIHTHPHHAHHLPIPPVPHLPPPPALFKSEPLNHRSQSEDTFLRHLAEKNSAAPAQHH", "length": 608 }, "evidence": [ { "id": "E1BQL6", "url": "https://omabrowser.org/oma/group/E1BQL6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2D9-1", "protein_name": "Zinc finger protein 652", "gene_name": "ZNF652", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHTASSCQELVENCAVHVAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYSVLVDTKMSKPHLHETEEQPYFRETRAVSDVHAVKEDRENSDDTEEEEEEVSYKREQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENEKQKKKEKIVEKVSVTQRRTRRAASVAAATTSPTPRTTRGRRKSVEPPKRKKRATKEPKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEKCFRVTSPVNVPPAVQIPLTTSPATPVPSVVNTATTPTPPINMNPVSTLPPRPIPHPFSHLHIHPHPHHPHHLPIPPVPHLPPPPALFKSEPLNHRGQSEDNFLRHLAEKNSSAQHH", "length": 606 }, "evidence": [ { "id": "E1BQL6", "url": "https://omabrowser.org/oma/group/E1BQL6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1BQL6", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQL6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 609, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQL6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQL6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQL6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 276, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 530 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQM7-1", "uniprot_ac": "E1BQM7", "uniprot_id": "E1BQM7_CHICK", "mass": { "chemical_mass": 34429.0, "monoisotopic_mass": 34429.0 }, "refseq": { "ac": "XP_001234493", "name": "phosducin-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234493" }, "gene_names": [ { "name": "PDCL", "type": "recommended", "evidence": [ { "id": "E1BQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" } ] }, { "name": "PDCL", "type": "synonym", "evidence": [ { "id": "XP_001234493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234493" } ] } ], "protein_names": [ { "name": "Phosducin like", "type": "synonym", "evidence": [ { "id": "E1BQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQM7/entry#names_and_taxonomy" } ] }, { "name": "phosducin-like protein", "type": "synonym", "evidence": [ { "id": "XP_001234493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234493" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234493" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQM7", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDCL", "url": "https://www.uniprot.org/uniprotkb/E1BQM7", "locus": { "chromosome": "17", "start_pos": 9382542, "end_pos": 9385030, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028377", "url": "https://www.ensembl.org/id/ENSGALG00010028377" } ] } } ], "crossref": [ { "id": "E1BQM7", "url": "https://alphafold.ebi.ac.uk/entry/E1BQM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001275", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "772371", "url": "https://www.ncbi.nlm.nih.gov/gene/772371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772371", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIIEMMP", "url": "https://omabrowser.org/oma/group/GIIEMMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BQM7", "url": "https://www.orthodb.org/?gene=E1BQM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46052:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46052:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001234493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BQM7", "url": "https://www.uniprot.org/uniprotkb/E1BQM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSSSEGEDEDSEKEDKEGESSIPDSVGEVELSSDGSAVNTGPKGVINDWRRFKQLETEQRQEQRREMERLIKKLSMTCRSHLDEETDKQKQKELQEKINGKMTLQEYNMIHNDEDDEEFLQRYRKQRMEEMRQQLYSGQQFKQVFEITSGEAFLDTVDKEHKSTLIMIHIYEDDIPGAESLHGCMICLAAEYPTVKFCKVKSSLIGASARFTNNALPALLVYKAGELIGNFVRITDQLGEDFFAVDLEAFLQECGLLPEKDLVLLTSIHNPSACYSEDSDLEID", "length": 300, "header": "tr|E1BQM7-1|E1BQM7_CHICK Isoform 1 of Phosducin like OS=Gallus gallus OX=9031 GN=PDCL PE=3 SV=1 CANONICAL=E1BQM7-1" }, "isoforms": [ { "isoform_ac": "E1BQM7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQM7/entry#E1BQM7-1", "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSSSEGEDEDSEKEDKEGESSIPDSVGEVELSSDGSAVNTGPKGVINDWRRFKQLETEQRQEQRREMERLIKKLSMTCRSHLDEETDKQKQKELQEKINGKMTLQEYNMIHNDEDDEEFLQRYRKQRMEEMRQQLYSGQQFKQVFEITSGEAFLDTVDKEHKSTLIMIHIYEDDIPGAESLHGCMICLAAEYPTVKFCKVKSSLIGASARFTNNALPALLVYKAGELIGNFVRITDQLGEDFFAVDLEAFLQECGLLPEKDLVLLTSIHNPSACYSEDSDLEID", "length": 300, "header": "tr|E1BQM7-1|E1BQM7_CHICK Isoform 1 of Phosducin like OS=Gallus gallus OX=9031 GN=PDCL PE=3 SV=1 CANONICAL=E1BQM7-1" }, "locus": { "chromosome": "17", "start_pos": 9385024, "end_pos": 9383113, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068746.1", "url": "https://www.ensembl.org/id/ENSGALT00010068746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042236.1", "url": "https://www.ensembl.org/id/ENSGALP00010042236.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772371", "resource": "KEGG Pathway" }, { "id": "R-GGA-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZXX5-1", "protein_name": "Phosducin-like protein", "gene_name": "PDCL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKERGRGALAGSSMPADAELAGEGISVNTGPKGVIHDWRRYKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKDFAMLNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEIPSGEGFLDMIDKEPKGTLIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCRVKSSVIGASSRFTRNALPALLIYKGGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLLLTSVRSSASCHSEDSDLEID", "length": 301 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QTL0-1", "protein_name": "1.14.99.1", "gene_name": "pdcl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTTLDDKILGEKLQYYYSSSEDEESDHEEDENAHKTIRDQEVLDVELDYSADGSSVNTGPKGVINDWRKYKQLENEQRIEQQKEMEKLIKKLSMTCKSHLEEEADKQKQKELQDKLTGKLNLRVDEEEEEDDDDEAFLQQYRLQRMEQMRRQLCGGRRFEKVMDISSGEEFLRAVDEEGKSTLVLVHIYEPEVPACQAMDGSLLCLALQYPMVKFCRVRGSAVGTSALFRSSALPALLLYRGGDLVGNLVRVSDQLGDDFYATDVEALLQEYGLLPEKYAQPNTHSSIRNAAVTHPDDSDSDLDID", "length": 306 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HLG7-1", "protein_name": "Phosducin-like protein", "gene_name": "Pdcl", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSTSEDEDSDHEDRDGDSGAPASSSIPVEAELASEGISINTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSNLDEEEEQKKQKDLQEKISGKMTLKEFATVDKNLDDEEFLQQYRKQRMEEMRQQFQKGPQFKQVFEIPSGEGFLDMIDKEQKNTLIMVHIYEDGIPGTEAMNGCMICLATEYPAVKFCRVKSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "length": 301 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q13371-1", "protein_name": "Phosducin-like protein", "gene_name": "PDCL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "length": 301 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJA9-1", "protein_name": "Phosducin-like protein", "gene_name": "PDCL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSSSEEEDSDHEDKDRGRGALAGSSMPADADLAGEGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSLSCRSHLDEEEEQRKQKDLQEKISGKMTLKDLAVMNEDQDDEEFLQQYRKQRMEEMRQQLYQGPQFKQVFEIPSGEGFLDMIDKEQRSTLIMVHIYEDGIPGTEAMNGCMLCLAAEYPAVKFCRVRSSVIGASSRFTRNALPALLIYKGGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLLRTSVRNSATCHSEDSDLEID", "length": 301 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q63737-1", "protein_name": "Phosducin-like protein", "gene_name": "Pdcl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSTSEDEDSDHEDKDRGRGAPASSSTPAEAELAGEGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKECGMMDKNLDDEEFLQQYRKQRMDEMRQQLHKGPQFKQVLEIPSGEGFLDMIDKEQKSTLIMVHIYEDGVPGTEAMNGCMICLAAEYPTVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "length": 301 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q71A39-1", "protein_name": "Phosducin-like protein 1", "gene_name": "phlp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEQNILNSILDKFGDGDQERSDIRHNDSGDENDNHSDHEGNHGNNECCEGNEDGDKEYEVDVEDMTDEQYAQFIQEQQEPKIKSGGNTGVKGVLSDYAEHREKQKQKYLQKKYETQKMLEKMCFTTRDQPPPTEEENQLDSDDDDLERIRKARMEQWKSKQQITSDVKKPEKKVFGYFKQIDSSQYIHEIDNEPPNVFVIIHLFQNYIPECVLLNQQLGQLAVKYRYIKFLKILSKEAKENYHDEALPSLLVYIGGKLLVSFVPLTEELGRNFDQEDLELLLSSYDIIPNPMKAKNSNWETSLSRKRPESDDDNDD", "length": 316 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DBX2-1", "protein_name": "Phosducin-like protein", "gene_name": "Pdcl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTLDDKLLGEKLQYYYSTSEDEDSDHEDKDRGRGAPAISSTPAEAELAGEGISINTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKEFGTKDKNLDDEEFLQQYRKQRMEEMRQQFHKGPQFKQVFEIPSGEGFLDMIDKEQKSTLIMVHIYEDGVPGTEAMNGCMICLATEYPAVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "length": 301 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VUR7-1", "protein_name": "Phosducin-like protein 1", "gene_name": "PhLP1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATLEDKLLGEKLEYYCSSSEGEDNGDEGGDNKGASGKSRCSGLTIDTNPDATPAGGFRQQSSTNTGPKGVVKDWQRFKQLEAERRDETERQRLALAKKLTITATTSAEDEERKRQEELDAELDELMSEDFLQQYQKQRMAEMLRQTGHHQQFGQVQQLTSHEEFLACVEQENKHTTIIIHIYERQLAACATLNKCLDSLASDYPSIKFAKICSSVAGMSRDFRTKGLPALLVYKAQAVIGNFVRLTDDLSDDFFASDVESFLIEHGIIVDRALYN", "length": 276 }, "evidence": [ { "id": "E1BQM7", "url": "https://omabrowser.org/oma/group/E1BQM7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "E1BQM7", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "E1BQM7", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" } ], "pmid": "" }, { "name": "heterotrimeric G-protein complex assembly", "id": "GO:1902605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902605", "evidence": [ { "database": "UniProtKB", "id": "E1BQM7", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "E1BQM7", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BQM7", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQM7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 300, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQM7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQM7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQM7" }, { "id": "PF02114", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02114" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosducin", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 298, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQN2-1", "uniprot_ac": "E1BQN2", "uniprot_id": "E1BQN2_CHICK", "mass": { "chemical_mass": 175946.0, "monoisotopic_mass": 175946.0 }, "refseq": { "ac": "XP_004944789", "name": "FYVE, RhoGEF and PH domain-containing protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944789" }, "gene_names": [ { "name": "FGD5", "type": "recommended", "evidence": [ { "id": "E1BQN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN2" } ] }, { "name": "FGD5", "type": "synonym", "evidence": [ { "id": "XP_004944789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944789" } ] } ], "protein_names": [ { "name": "FYVE, RhoGEF and PH domain containing 5", "type": "synonym", "evidence": [ { "id": "E1BQN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN2/entry#names_and_taxonomy" } ] }, { "name": "FYVE, RhoGEF and PH domain-containing protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004944789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944789" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944789" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQN2", "url": "https://www.uniprot.org/uniprotkb/E1BQN2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGD5", "url": "https://www.uniprot.org/uniprotkb/E1BQN2", "locus": { "chromosome": "12", "start_pos": 19967967, "end_pos": 20057160, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022028", "url": "https://www.ensembl.org/id/ENSGALG00010022028" } ] } } ], "crossref": [ { "id": "ENSGALG00000008546", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008546", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13237", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13237", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15742", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15742", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15792", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15792", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416130", "url": "https://www.ncbi.nlm.nih.gov/gene/416130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416130", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LTNPYVM", "url": "https://omabrowser.org/oma/group/LTNPYVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U3H3", "url": "https://www.orthodb.org/?gene=A0A3Q2U3H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLE1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZTW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQN2", "url": "https://www.orthodb.org/?gene=E1BQN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12673:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12673:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004944789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944789", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3H3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQN2", "url": "https://www.uniprot.org/uniprotkb/E1BQN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQN2-1", "url": "https://www.uniprot.org/uniprotkb/E1BQN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNTELTKPPLAPKPKIIGHLSPVAISKFSPSLPRSDILHNPNSMSRGPKPPIAPKPKLSADTESRSSVNTNNNLNKCSNCKLLCLDGELCDGNQCSAECPEAEADDEYIVLPETQLTNKDCNDLEHKHDQSLDSFAVNEVLEIPEEAEKEEDNIPNHESADSQEIKHHNFSDIAEPIKPDSVSSTRDRGQSEAFCEELSDATGGNNDVSKNVDEDKDVAGDCSETRSKEETSNNLKLVKDSDDSKTDGDNILNRDEGDVCGDIILTPLTAAELIPSLEKSGEEKEEELSEILGKGDRCPAHDGDHSVYAELDLNMQDELENDDCTSPDMLPNEASEKTVWCLELPEGEPNAENGLGDSTHQAAAEEEEADTDKHNNTNTGNVSDDCQITDLRGEETSEVACEASKDSGKREEETVNAESINDGCQIAPSENDDGEEVPTNRQTEETCPEEDGQISDTLPSGPGMETKLEDMSAEEHNESIAEMSKSDELQLEGNKVETDSLSKSDLSPTQLVPCKEEIEVCKHGKMNVKHRTKNVLHEKLALPEVVIVPEESERRETGSDSLDDPYVLPAENEFTHKGQTDSGADHSKRDELDMDGESNLLLIDRKSIVTRTRSLSGRMPGYVPETVPEEGGPETDLPPSCNSSGTEDLSNSSFSVEGKTLEDNKALPSKPRHFILYPRSYSVEGREIPISIYKEGDGCVLSDIRMKKTEDNLSLPCVNGSSHIFSQGNLSSGAVSTPSSVVDIPPPFELAYITKKPITKSSPSLLIENESPDKYSKKKKSSFKRFLTLKFKKKTENKIHVDVNVSSSRSSSESSYHGPPRLMELDRTLSSSPQLKSHVGKLRASESPSTVFFYKDGKRKGTPKSFSRSVSRVESFEDRSRPPFMPLPLTKPRSISFPNADTSEYENIPAMSSDYENIQIPPRRSTRAGTFTEFFEDPSRALSAANENDGYVDMSSFTGFENKQQTTDQETESAYTEPYKVCPVSVIPAEVITSDEEQRSSEDEKSSQGDPSLINKKEGQPRASLIAQELMSSEKAYVEMLQLLRMDLYEGILKALGEEDEQEVVELKQGLSELPEMYELHQEILGELEERVLKWEEHQKVADVFLSRKSRLNHHTAYITQFDKNLALLDETCLKYSQLATVIQEFEKSSGGSPQNVKHQLLKVVQRVFQYRVMLTDYLNNLCPDSTEYEATQAALFIVSEIADRANESMLQGENLQKLVHIEHSVRGQSGLLQPGRIFVKEGTLMKVSGKNRHPRHLFLMNDVLLYTYPQKDGKYQLKNTLVVSDMKVSRPVTEKAPNVLKIECDEYCLTLSASSCLERDDWYSCISRHIPDDCKAHNTSTCHSNVELRERLGIPLGERPPTLVPVSHVMMCMNCGCDFTLTLRRHHCHACGKIVCRNCSRNKYPMKYLRDQAAKVCDSCYVELKKRERPLSVSFPPTSSRCSSSAFSSVFHNIHYSSFKKQKKIPSALTEVAASGEGATISGYLTRCKRGKRHWKKRWFVIKGKVLYTYIANEDKVATESLPLLGFTVAPEKEEGCIDTVFHLYHKQTLFYSFRADDNYSAQRWIEAMEEASIL", "length": 1577, "header": "tr|E1BQN2-1|E1BQN2_CHICK Isoform 1 of FYVE, RhoGEF and PH domain containing 5 OS=Gallus gallus OX=9031 GN=FGD5 PE=4 SV=2 CANONICAL=E1BQN2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U3H3-1", "url": "https://www.uniprot.org/uniprotkb/E1BQN2/entry#A0A3Q2U3H3-1", "sequence": { "sequence": "MNNTELTKPPLAPKPKIIGHLSPVAISKFSPSLPRSDILHNPNSMSRGPKPPIAPKPKLSADTESRSSVNTNNNLNKCSNCKLLCLDGELCDGNQCSAECPEAEADDEYIVLPETQLTNKDCNDLEHKHDQSLDSFAVNEVLEIPEEAEKEEDNIPNHESADSQEIKHHNFSDIAEPIKPDSVSSTRDRGQSEAFCEELSDATGGNNDVSKNVDEDKDVAGDCSETRSKEETSNNLKLVKDSDDSKTDGDNILNRDEGDVCGDIILTPLTAAELIPSLEKSGEEKEEELSEILGKGDRCPAHDGDHSVYAELDLNMQDELENDDCTSPDMLPNEASEKTVWCLELPEGEPNAENGLGDSTHQAAAEEEEADTDKHNNTNTGNVSDDCQITDLRGEETSEVACEASKDSGKREEETVNAESINDGCQIAPSENDDGEEVPTNRQTEETCPEEDGQISDTLPSGPGMETKLEDMSAEEHNESIAEMSKSDELQLEGNKVETDSLSKSDLSPTQLVPCKEEIEVCKHGKMNVKHRTKNVLHEKLALPEVVIVPEESERRETGSDSLDDPYVLPAENEFTHKGQTDSGADHSKRDELDMDGESNLLLIDRKSIVTRTRSLSGRMPGYVPETVPEEGGPETDLPPSCNSSGTEDLSNSSFSVEGKTLEDNKALPSKPRHFILYPRSYSVEGREIPISIYKEGDGCVLSDIRMKKTEDNLSLPCVNGSSHIFSQGNLSSGAVSTPSSVVDIPPPFELAYITKKPITKSSPSLLIENESPDKYSKKKKSSFKRFLTLKFKKKTENKIHVDVNVSSSRSSSESSYHGPPRLMELDRTLSSSPQLKSHVGKLRASESPSTVFFYKDGKRKGTPKSFSRSVSRVESFEDRSRPPFMPLPLTKPRSISFPNADTSEYENIPAMSSDYENIQIPPRRSTRAGTFTEFFEDPSRALSAANENDGYVDMSSFTGFENKQQTTDQETESAYTEPYKVCPVSVIPAEVITSDEEQRSSEDEKSSQGDPSLINKKEGQPRASLIAQELMSSEKAYVEMLQLLRMDLYEGILKALGEEDEQEVVELKQGLSELPEMYELHQEILGELEERVLKWEEHQKVADVFLSRKSRLNHHTAYITQFDKNLALLDETCLKYSQLATVIQEFEKSSGGSPQNVKHQLLKVVQRVFQYRVMLTDYLNNLCPDSTEYEATQAALFIVSEIADRANESMLQGMNDVLLYTYPQKDGKYQLKNTLVVSDMKVSRPVTEKAPNVLKIECDEYCLTLSASSCLERDDWYSCISRHIPDDCKAHNTSTCHSNVELRERLGIPLGERPPTLVPVSHVMMCMNCGCDFTLTLRRHHCHACGKIVCRNCSRNKYPMKYLRDQAAKVCDSCYVELKKRERPLSVSFPPTSSRCSSSAFSSVFHNIHYSSFKKQKKIPSALTEVAASGEGATISGYLTRCKRGKRHWKKRWFVIKGKVLYTYIANEDKVATESLPLLGFTVAPEKEEGCIDTVFHLYHKQTLFYSFRADDNYSAQRWIEAMEEASIL", "length": 1530, "header": "tr|A0A3Q2U3H3-1|A0A3Q2U3H3_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 5 OS=Gallus gallus OX=9031 GN=FGD5 PE=4 SV=1 CANONICAL=E1BQN2-1" }, "locus": { "chromosome": "12", "start_pos": 20056026, "end_pos": 19969289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053549.1", "url": "https://www.ensembl.org/id/ENSGALT00010053549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032265.1", "url": "https://www.ensembl.org/id/ENSGALP00010032265.1" } ] } }, { "isoform_ac": "A0A8V0ZLE1-1", "url": "https://www.uniprot.org/uniprotkb/E1BQN2/entry#A0A8V0ZLE1-1", "sequence": { "sequence": "MSRGPKPPIAPKPKLSADTESRSSVNTNNNLNKCSNCKLLCLDGELCDGNQCSAECPEAEADDEYIVLPETQLTNKDCNDLEHKHDQSLDSFAVNEVLEIPEEAEKEEDNIPNHESADSQEIKHHNFSDIAEPIKPDSVSSTRDRGQSEAFCEELSDATGGNNDVSKNVDEDKDVAGDCSETRSKEETSNNLKLVKDSDDSKTDGDNILNRDEGDVCGDIILTPLTAAELIPSLEKSGEEKEEELSEILGKGDRCPAHDGDHSVYAELDLNMQDELENDDCTSPDMLPNEASEKTVWCLELPEGEPNAENGLGDSTHQAAAEEEEADTDKHNNTNTGNVSDDCQITDLRGEETSEVACEASKDSGKREEETVNAESINDGCQIAPSENDDGEEVPTNRQTEETCPEEDGQISDTLPSGPGMETKLEDMSAEEHNESIAEMSKSDELQLEGNKVETDSLSKSDLSPTQLVPCKEEIEVCKHGKMNVKHRTKNVLHEKLALPEVVIVPEESERRETGSDSLDDPYVLPAENEFTHKGQTDSGADHSKRDELDMDGESNLLLIDRKSIVTRTRSLSGRMPGYVPETVPEEGGPETDLPPSCNSSGTEDLSNSSFSVEGKTLEDNKALPSKPRHFILYPRSYSVEGREIPISIYKEGDGCVLSDIRMKKTEDNLSLPCVNGSSHIFSQGNLSSGAVSTPSSVVDIPPPFELAYITKKPITKSSPSLLIENESPDKYSKKKKSSFKRFLTLKFKKKTENKIHVDVNVSSSRSSSESSYHGPPRLMELDRTLSSSPQLKSHVGKLRASESPSTVFFYKDGKRKGTPKSFSRSVSRVESFEDRSRPPFMPLPLTKPRSISFPNADTSEYENIPAMSSDYENIQIPPRRSTRAGTFTEFFEDPSRALSAANENDGYVDMSSFTGFENKQQTTDQETESAYTEPYKVCPVSVIPAEVITSDEEQRSSEDEKSSQGDPSLINKKEGQPRASLIAQELMSSEKAYVEMLQLLRMDLYEGILKALGEEDEQEVVELKQGLSELPEMYELHQEILGELEERVLKWEEHQKVADVFLSRKSRLNHHTAYITQFDKNLALLDETCLKYSQLATVIQEFEKSSGGSPQNVKHQLLKVVQRVFQYRVMLTAALFIVSEIADRANESMLQGENLQKLVHIEHSVRGQSGLLQPGRIFVKEGTLMKVSGKNRHPRHLFLMNDVLLYTYPQKDGKYQLKNTLVVSDMKVSRPVTEKAPNVLKIECDEYCLTLSASSCLERDDWYSCISRHIPDDCKAHNTSTCHSNVELRERLGIPLGERPPTLVPVSHVMMCMNCGCDFTLTLRRHHCHACGKIVCRNCSRNKYPMKYLRDQAAKVCDSCYVELKKRERPLSVSFPPTSSRCSSSAFSSVFHNIHYSSFKKQKKIPSALTEVAASGEGATISGYLTRCKRGKRHWKKRWFVIKGKVLYTYIANEDKVATESLPLLGFTVAPEKEEGCIDTVFHLYHKQTLFYSFRADDNYSAQRWIEAMEEASIL", "length": 1516, "header": "tr|A0A8V0ZLE1-1|A0A8V0ZLE1_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 5 OS=Gallus gallus OX=9031 GN=FGD5 PE=4 SV=1 CANONICAL=E1BQN2-1" }, "locus": { "chromosome": "12", "start_pos": 20045500, "end_pos": 19969289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053539.1", "url": "https://www.ensembl.org/id/ENSGALT00010053539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032257.1", "url": "https://www.ensembl.org/id/ENSGALP00010032257.1" } ] } }, { "isoform_ac": "A0A8V0ZTW1-1", "url": "https://www.uniprot.org/uniprotkb/E1BQN2/entry#A0A8V0ZTW1-1", "sequence": { "sequence": "MSRGPKPPIAPKPKLSADTESRSSVNTNNNLNKCSNCKLLCLDGELCDGNQCSAECPEAEADDEYIVLPETQLTNKDCNDLEHKHDQSLDSFAVNEVLEIPEEAEKEEDNIPNHESADSQEIKHHNFSDIAEPIKPDSVSSTRDRGQSEAFCEELSDATGGNNDVSKNVDEDKDVAGDCSETRSKEETSNNLKLVKDSDDSKTDGDNILNRDEGDVCGDIILTPLTAAELIPSLEKSGEEKEEELSEILGKGDRCPAHDGDHSVYAELDLNMQDELENDDCTSPDMLPNEASEKTVWCLELPEGEPNAENGLGDSTHQAAAEEEEADTDKHNNTNTGNVSDDCQITDLRGEETSEVACEASKDSGKREEETVNAESINDGCQIAPSENDDGEEVPTNRQTEETCPEEDGQISDTLPSGPGMETKLEDMSAEEHNESIAEMSKSDELQLEGNKVETDSLSKSDLSPTQLVPCKEEIEVCKHGKMNVKHRTKNVLHEKLALPEVVIVPEESERRETGSDSLDDPYVLPAENEFTHKGQTDSGADHSKRDELDMDGESNLLLIDRKSIVTRTRSLSGRMPGYVPETVPEEGGPETDLPPSCNSSGTEDLSNSSFSVEGKTLEDNKALPSKPRHFILYPRSYSVEGREIPISIYKEGDGCVLSDIRMKKTEDNLSLPCVNGSSHIFSQGNLSSGAVSTPSSVVDIPPPFELAYITKKPITKSSPSLLIENESPDKYSKKKKSSFKRFLTLKFKKKTENKIHVDVNVSSSRSSSESSYHGPPRLMELDRTLSSSPQLKSHVGKLRASESPSTVFFYKDGKRKGTPKSFSRSVSRVESFEDRSRPPFMPLPLTKPRSISFPNADTSEYENIPAMSSDYENIQIPPRRSTRAGTFTEFFEDPSRALSAANENDGYVDMSSFTGFENKQQTTDQETESAYTEPYKVCPVSVIPAEVITSDEEQRSSEDEKSSQGDPSLINKKEGQPRASLIAQELMSSEKAYVEMLQLLRMDLYEGILKALGEEDEQEVVELKQGLSELPEMYELHQEILGELEERVLKWEEHQKVADVFLSRKSRLNHHTAYITQFDKNLALLDETCLKYSQLATVIQEFEKSSGGSPQNVKHQLLKVVQRVFQYRVMLTDYLNNLCPDSTEYEATQAALFIVSEIADRANESMLQGENLQKLVHIEHSVRGQSGLLQPGRIFVKEGTLMKVSGKNRHPRHLFLMNDVLLYTYPQKDGKYQLKNTLVVSDMKVSRPVTEKAPNVLKIECDEYCLTLSASSCLERDDWYSCISRHIPDDCKAHNTSTCHSNVELRERLGIPLGERPPTLVPVSHVMMCMNCGCDFTLTLRRHHCHACGKIVCRNCSRNKYPMKYLRDQAAKVCDSCYVELKKRERPLSVSFPPTSSRCSSSAFSSVFHNIHYSSFKKQKKIPSALTEVAASGEGATISGYLTRCKRGKRHWKKRWFVIKGKVLYTYIANEDKVATESLPLLGFTVAPEKEEGCIDTVFHLYHKQTLFYSFRADDNYSAQRWIEAMEEASIL", "length": 1533, "header": "tr|A0A8V0ZTW1-1|A0A8V0ZTW1_CHICK Computationally mapped isoform of FYVE, RhoGEF and PH domain containing 5 OS=Gallus gallus OX=9031 GN=FGD5 PE=4 SV=1 CANONICAL=E1BQN2-1" }, "locus": { "chromosome": "12", "start_pos": 20045500, "end_pos": 19969289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053564.1", "url": "https://www.ensembl.org/id/ENSGALT00010053564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032276.1", "url": "https://www.ensembl.org/id/ENSGALP00010032276.1" } ] } }, { "isoform_ac": "E1BQN2-1", "url": "https://www.uniprot.org/uniprotkb/E1BQN2/entry#E1BQN2-1", "sequence": { "sequence": "MNNTELTKPPLAPKPKIIGHLSPVAISKFSPSLPRSDILHNPNSMSRGPKPPIAPKPKLSADTESRSSVNTNNNLNKCSNCKLLCLDGELCDGNQCSAECPEAEADDEYIVLPETQLTNKDCNDLEHKHDQSLDSFAVNEVLEIPEEAEKEEDNIPNHESADSQEIKHHNFSDIAEPIKPDSVSSTRDRGQSEAFCEELSDATGGNNDVSKNVDEDKDVAGDCSETRSKEETSNNLKLVKDSDDSKTDGDNILNRDEGDVCGDIILTPLTAAELIPSLEKSGEEKEEELSEILGKGDRCPAHDGDHSVYAELDLNMQDELENDDCTSPDMLPNEASEKTVWCLELPEGEPNAENGLGDSTHQAAAEEEEADTDKHNNTNTGNVSDDCQITDLRGEETSEVACEASKDSGKREEETVNAESINDGCQIAPSENDDGEEVPTNRQTEETCPEEDGQISDTLPSGPGMETKLEDMSAEEHNESIAEMSKSDELQLEGNKVETDSLSKSDLSPTQLVPCKEEIEVCKHGKMNVKHRTKNVLHEKLALPEVVIVPEESERRETGSDSLDDPYVLPAENEFTHKGQTDSGADHSKRDELDMDGESNLLLIDRKSIVTRTRSLSGRMPGYVPETVPEEGGPETDLPPSCNSSGTEDLSNSSFSVEGKTLEDNKALPSKPRHFILYPRSYSVEGREIPISIYKEGDGCVLSDIRMKKTEDNLSLPCVNGSSHIFSQGNLSSGAVSTPSSVVDIPPPFELAYITKKPITKSSPSLLIENESPDKYSKKKKSSFKRFLTLKFKKKTENKIHVDVNVSSSRSSSESSYHGPPRLMELDRTLSSSPQLKSHVGKLRASESPSTVFFYKDGKRKGTPKSFSRSVSRVESFEDRSRPPFMPLPLTKPRSISFPNADTSEYENIPAMSSDYENIQIPPRRSTRAGTFTEFFEDPSRALSAANENDGYVDMSSFTGFENKQQTTDQETESAYTEPYKVCPVSVIPAEVITSDEEQRSSEDEKSSQGDPSLINKKEGQPRASLIAQELMSSEKAYVEMLQLLRMDLYEGILKALGEEDEQEVVELKQGLSELPEMYELHQEILGELEERVLKWEEHQKVADVFLSRKSRLNHHTAYITQFDKNLALLDETCLKYSQLATVIQEFEKSSGGSPQNVKHQLLKVVQRVFQYRVMLTDYLNNLCPDSTEYEATQAALFIVSEIADRANESMLQGENLQKLVHIEHSVRGQSGLLQPGRIFVKEGTLMKVSGKNRHPRHLFLMNDVLLYTYPQKDGKYQLKNTLVVSDMKVSRPVTEKAPNVLKIECDEYCLTLSASSCLERDDWYSCISRHIPDDCKAHNTSTCHSNVELRERLGIPLGERPPTLVPVSHVMMCMNCGCDFTLTLRRHHCHACGKIVCRNCSRNKYPMKYLRDQAAKVCDSCYVELKKRERPLSVSFPPTSSRCSSSAFSSVFHNIHYSSFKKQKKIPSALTEVAASGEGATISGYLTRCKRGKRHWKKRWFVIKGKVLYTYIANEDKVATESLPLLGFTVAPEKEEGCIDTVFHLYHKQTLFYSFRADDNYSAQRWIEAMEEASIL", "length": 1577, "header": "tr|E1BQN2-1|E1BQN2_CHICK Isoform 1 of FYVE, RhoGEF and PH domain containing 5 OS=Gallus gallus OX=9031 GN=FGD5 PE=4 SV=2 CANONICAL=E1BQN2-1" }, "locus": { "chromosome": "12", "start_pos": 20056026, "end_pos": 19969289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053557.1", "url": "https://www.ensembl.org/id/ENSGALT00010053557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032271.1", "url": "https://www.ensembl.org/id/ENSGALP00010032271.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 738, "start_aa": "Thr", "end_pos": 738, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr738", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416130", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416130", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M7Z7-1", "protein_name": "FYVE, RhoGEF and PH domain containing 5", "gene_name": "FGD5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRADSPKPPVAPKPKAASSLTPQTPPKFCPSSLRPESLHSPNSSMSRGPKPPIAPKPRLATPSEWRASVYVINSLNKCSNGKLPCVDRGLYEEHRSTPECSESEADEDYIVAPRAPPGEDGARDAGCVENAVTGPPEAGEEEEGQDGGEGCGPAGSAAAEAWAVLSEQADRDVAPAPEDAEGPDCAGAVGTEDQTLASEEEEEKLAEEHRACSLEDEDGEAEPGEPGDGGAEPGDGWAESLSDSIPAHLEVLEDTVVGGEEEPGAPGTPQEAEEEDAEPGHSVDEGGEGDDAGEEPPEDEESATGVPEAEVASDDPEVSREACEDAAGYGGQHDGQDEPADPAEAEAGQDPRQGEDPVQDEAAEESCHIIPFESDSVDDLVPPLSASPYEFFPTESTSFCSESYPPYSESAGESAQEPGPEERAERDPEAGPGRERRGSAQGGAGEEGAPVPDVLVLPEDEDANPYEMGVGPTCEADPGEAETPGAQAALQELSPDAEGGLVPIDRKNVMARARPHSGKLAGYVPETVPEEMGPEAGSAAAGVGAAAAEGRKTVLSLEGKPLDVGRALPAKPRGFTLYPRSFSVEGREIPVSLYREPEACGLEGHGIKRKEDNLSLPCVIGSSGSFSQRSHLPSSGTSTPSSMVDIPPPFDLACITKKPITKSSPSLLVESEPPDKHSKKKKSSFKRFLALTFKKKTESKVHVDVNVSSSRSSSESSYHGPARLLEMDRRSLSNSPQLRARTGKLRACDSPSSLIFCREGKRKGVPFSRTVSRVESFEDRSRPPFLPLPLTKPRSISFPNADTSDYENIPAMNSDYENIQIPPRRPARAGTFTKLFEDQSRALSTANENDGYVDMSSFNAFESKPQSADPEAESAYTEPYKVCPISAVAPKEDLTSEEERGSSEEEEDRAARDPTLPHKVEGQSRAHVIAQELLSSEKAYVEMLQHLYLDFHGAVVRALDEMDYEGKDPVGREELRRGLSELPAIHDLHQGILEELEERLAHWEGQQKVADVFLAREQEFAHHATHILQFDRYLSLLGENCLHAPRLAAAVREFEQSQQGGGQNVKHRLLRVVRRLFQYEALLTDYLNNLCPDSAEYDDTQGALTLISKITDRANDSMEQGENLQKLVHIEHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMSDVLLYTYPQKDGKYRLKSALAVASMKVSRPVMEKVPYALKIETPESCLTLSASSCAERDEWHSCVSRALPEDYKAQALAAFQHSVEEGGRRPSWSPDPAARLTPLLQIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCYGELKKRGGDAPGMMRERPLSMSFPLSSARFSSSAFSSVFHSINPSAFRKQRKVPSALTEVAASGEGSAISGYLNRCKKGKRHWKKLWFVINGKVLYTYAAREDTVALESMPLLGFTVASSKEEGSSEASPTFHLYHKKTLFYSFKAEDSSLAQRWIEAMEDASVL", "length": 1517 }, "evidence": [ { "id": "E1BQN2", "url": "https://omabrowser.org/oma/group/E1BQN2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I5ZMC4-1", "protein_name": "FYVE, RhoGEF and PH domain containing 5", "gene_name": "Fgd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VAPKPKVTTNPSTPPAKFPASQRPNSFPSPNSMSRGPKPPIAPKPRLAGPSEYGAGVYLNNSLSKCSNGRLLCEDPSLYDGHHSTLNCLELETDEQYIMVPRAPQRDDALTDRATEKQGFEGEAQEHGTEQTGTERDLAAPDEEAPSRDSEEGVDHALEDEEDCDHDLETDGTPTAPGEGAPSRDGEKGEEDCGQDPGVEEHPMSEEEGEEEEAKECVHNRDDRAPWDGGEPFLNEVVLTHVCSQSPEVPCWEPGLPETPGEVDEDSEDICNNTELGKPNQDTGQDTEDASMGSPESEVSPDVQEQEAATDSPEVFEEDSVDAAEGEDQIARDEPPNCEEDTNNRETAAATMQAGEDHGEDGDRVQEDPAEENCQIIPFESDSVEEDCSPTLTENPYELFPTESTSFCNNSGSLAESDKGQESVCKICVEEVPGIGPSLSQGDSLQDGSGEEAPVPEVVVVPENEDPMDDALSSPYVMGVGLLSLGEGAQSDTQAASGTLSGYSTWEEGDSDGGQVPVDRKNIATRARPHSGKVAGHVPETVLEETGPEACSSAMGIRDTGDEVRKIGILPEGKPSESLRALPAKPRAFTLYPRSFSVEGRESPLSMFREPEGAGLDMHRVRRKEDNLSLPGAIGSSGSFSQRSHLPSSGTSTPSSVVDIPPPFDLACITKRPITKSSPSLLIDGDTLEKASKKKKSSFKRFLELTFRKKTESKVHVDMSLSSSRSSSESSYHGPARVLELDRRSLSNSPQLKCHTGKLRASDSPASLIFYRDSKRKGVPFSRTVSRVESFEDRSRPPFLPLPLTKPRSISFPNADTSDYENIPAMNSDYENIQIPPRRPARTGTFTKLFEEQSRALSTANENDGYVDMSSFNAFESKQQSSEQEAESAYTEPYKVCPISTTPKEDLTSDEEQGSSEEEDNASRDPSLSHKGEGQSRAFVIAQELLSSEKAYVQMLQHLSLDFHGAVLRALENVEQEGREPLAQEELRQGLRELPAICDLHQGILESLEQRLGDCGEGQQQVADIFLAREQEFEHHAAHILQFDRYLGLLAESCLLSPRLATTVREFEQSSQGGGQSMKHRMLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQSNEGVTISCACPQENLQKLVHIEYSVRGQGDLLQPGREFLKEGTLMRVRGKSRHPRHLFLMNDTLLYTHPQKDGKYRLKSSLPVANMKVSRPVMDKVPYALKIETPESCLTLSASSCAERDEWHYCLSRALPEDYKTQALAAFHHSVEIRERLGISLGERLPTLVPVTHAMMCMNCGCDFSLTVRRHHCHACGKIVCRNCSRNKYPLKCLKNRMAKVCDGCFRELKLRNGPVPGPIRERPVSMSFPLSSSRFSSGSTFSSVFQSISPSTFKKQKKVPSALAEVAASGEGSAISGYLSRCKSGKRRWKKLWLVIKGKVLYTYLASEDKVAMESIPLLGFTIAPEKEEGSSEVGPVFHLYHKKTLFYSFKAEDSSSAQRYQQQIAFYFLVCLAEKCRLALHCSMQAPGGPSTAAGLHVLSHET", "length": 1535 }, "evidence": [ { "id": "E1BQN2", "url": "https://omabrowser.org/oma/group/E1BQN2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9QLY3-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 5 isoform X1", "gene_name": "fgd5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRPCPSTRGPKPPVAPKPRLASEVSHSIVGNGDITSSDRLELKQDNKSDVAQEESDKSRENCTDDQAENDLYDKEFAVNYDTTCYDEIEDKLQMAVDETMGEDEDKNVTEIQHATTLSLSEAVDECLDSADEFHSKSADDIKPAESREVIYNVLEDTSACSENDTSTKACESQSPYEEIEEPPLNSFQCANGQYEEDIGAGANCVHHEAEEDGTGLSSKATNCSQPSLCEEYPYDIIGTLDDNNTWQAERATKDPSGRFRFAEETEDAFEPYSVIEVVPSDLMCTADPETRCTDEESSNVKPMDSENTTEGTSNQEPYYVSSEDVEDLEEEQAKLENGVSLPASEVQEMDKNEEVDDYADIEDHEGDDHQVECASSEDYVEIGDEDEPLNMERKTKGKSVRERSARRRHDLLSQRNSCQPRLRLCNITVPADLDLGRTPELTNRVVFAHTTEAFEEDIEELDCHIVPFFEDSDTESDEHIYEEAGFDSEGENFISLDRKSIVTRSRSLSGKVPGYVPETVPEETGTEYQSHDYYTVALDQNGDPHPKPSDEAEANRIIPSLKPRRFLLSPRSLSVEGRDLQLSGHFEGEKSLREEYRLQRKDDTLSLPCVITSSGSFSQRSHQSSSGVSTPTSLVDIPPPFELAYITKRPVTKSSPSLLIQHDSPDNPKKKKTSFKRFLALKFRKKSESKSRGDGSVRSSRSSSESSHHGPIRVLELDRRSTSGSPKLQSHAGKPQRNSEIPTTFLLYKERQSRQGALKSYNSRGISRVESFEDRTRPPFMPLPLTKPRSISFPSADTSDYENIPAMSSDYENIQIPHGRPTRAVTITEFFDDHNRTAAPANENDGYVDMNSFAGIENKSTTREQDTESAYTEPFPVCPVSATVSNEEDHGRTSEEEDGCGDHCHDRQIDGRSRAYYVAKDLVDSEREHVKALKVLQEDFRAAVESGGDDNGPLIENGKLDEIFSTLPQAYSLHSEILNELETRIKQWEDSPTVVDVILTRRAEFSSFATYISNYDRSMSVLDESCRKSQAFEDVVKQFETQNAEGVLVPLKHQLLRVIVRILQYRMLLTDYLNNLSPDSKEYEDTQAALVIVSEVADQVNDNLKHGENLLRLVHIDYSVRGKRDLLQPGRVFVKEGTLMKVSRKSRQPRHLFLMNDVMLYTYPQQDGKYRLKNTLTLSGMKVSKPIIDNVLNTLRIEVSDVTITLSASSLGEREDWFHTLSRAIADHAAGLNTFSSSSEAREKLWMSLGEAAPVLVPVSHVMMCMNCTSDFSLTLRRHHCNACGKVVCRSCSRNRYPLKYLKDRMAKVCDHCYAELRKRGGDVPGSCGSVSPRTHRASRPLSAVFQSLQPPSLWRNRKSSSPLTQVSVGAEGSTMSGSLQRRKKSKRRWKRLWFLLKDKVLYTFKAREDKVASESLSLQGFTVKLSDRSEGEDTDNVFQLYHKKTLYYTFRADDQPTARRWVNAMEEATVL", "length": 1473 }, "evidence": [ { "id": "E1BQN2", "url": "https://omabrowser.org/oma/group/E1BQN2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZNL6-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 5", "gene_name": "FGD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRGPKPPIAPKPRLTAPNEWRASVYLNDSLNKCSNGRLPCVDRGLDEGPRSIPKCSESETDEDYIVVPRVPLREDEPKDEGSVGNKALVSPESSAEEEEEREEGGEACGLEGTGAGEDSVAPAAPGAGALSREGEEGTDLALEDEGEGCADEPGTLEQVSRSEEEEKLVQPHRECSLEDSGPWAGEGVFQSDLLLPHIHGEDQEPPDTPGEAEEDDEEGCASTDPAGADEGSGPDRPTEDMGQDAEDTSEEPPEKEELAGVQEAETATDCPEVLEEGCEEATGVTGGEQVDLSEPPDHEKKTNQEVAAATLEDHAQDESAEESCQIVPFENDCMEDFVTSLTGSPYEFFPTESTSFCSESCSPLSESAKGLESEQAPKLGLRAEENPMVGALCGQCGSLQGGAAEGPAAPDVVVVLEEEALDDALANPYVMGVGLPGQAAPGEGGQAASDALGGYGSKEELNCEAEGGLVPADRKNTSTRVRPHSGKVAGYVPETVPEETGPEAGSSAPGIGGAAEEVGKTLLSLEGKPLEASRALPAKPRAFTLYPRSFSVEGREIPVSVYQEPEGSGLDDHRIKRKEDNLSLSCVIGSSGSFSQRNHLPSSGTSTPSSMVDIPPPFDLACITKKPITKSSPSLLIESDSPDKYKKKKSSFKRFLALTFKKKTENKLHVDVNVSSSRSSSESSYHGPSRILEVDRRSLSNSPQLKSRTGKLRASESPSSLIFYRDGKRKGVPFSRTVSRVESFEDRSRPPFLPLPLTKPRSISFPSADTSDYENIPAMNSDYENIQIPPRRPARAGAFTKLFEDQSRALSTANENDGYVDMSSFNAFESKQQSADQDAESAYTEPYKVCPISSAAPKEDLTSDEEQRSSEEEDSASRDPSVTHKVEGQSRALVIAQELLSSEKAYVEMLQHLNLDFHGAVMRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCLHSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQGALSLISKVTDRANDSMEQGENLQKLVHIEHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLYTYPQKDGKYRLKNTLAVANMKVSRPVMEKVPYALKIETSESCLMLSASSCAERDEWYGCLSRALPEDYKAQALAAFHHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSGSAFSSVFQSINPSTFKKQKKVPSALTEVAASGEGSAISGYLSRCKRGKRHWKKLWFVIKGKVLYTYMASEDKVALESMPLLGFTIAPEKEEGSSEVGPIFHLYHKKTLFYSFKAEDTNSAQRWIEAMEDASVL", "length": 1462 }, "evidence": [ { "id": "E1BQN2", "url": "https://omabrowser.org/oma/group/E1BQN2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80UZ0-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 5", "gene_name": "Fgd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSPESEVSPDVQEQEAATDNPEVFEEDSADAAEGEDQIEQEEPPNCDEEAYNRDAAAATMQVGEDLGEEGDHVQEDPAEESCQIIPFESDSVEEDFSPTLTENPYEIFPTESTSFCNNTYSLDESANGHEPVCEICVEEVPGVGPPLNQHDSLPDGSGEDSPVVPDVVVVPENEGPVDDALSSPYVMGVGLLSLGEGAQSDTQAASGTLSGYSTWEEGDSEGGQVPVDRKNIATRARPHSGKVAGHVPETVLEETGPETCSSGMGIRDTSDEVRKIGILPEGKPPECVRALPAKPRAFTLYPRSFSVEGRESPLSMFREPEGAGLDSHRVRRKEDNLSLPGAIGSSGSFSQRSHLPSSGTSTPSSVVDIPPPFDLACITKKPITKSSPSLLIDGDTLEKASKKKKSSFKRFLELTFRKKTESKVHVDMNLSSSRSSSESSYHGPARVLELDRRSLSNSPQLKCRTGKLRASDSPAALIFYRDSKRKGVPFSRTVSRVESFEDRSRPPFLPLPLTKPRSISFPNADTSDYENIPAMNSDYENIQIPPRRPVRTGTFTKLFEEQSRALSTANENDGYVDMSSFNAFESKQQSSEQEAESAYTEPYKVCPISAAPREDLTSDEEQGSSEEEDSASRDPSLSHKGEGQSRALVIAQELLSSEKAYVQMLQHLSLDFHGAVLRALENVEQEGREPLAQEELRQGLRELPAICDLHQGILESLEQRLGDCGEGQPQVADIFLAREQEFEHHAAHILQFDRYLGLLAESCLLSPRLATTVREFEQSSQGGGQSMKHRMLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQSALTLISKVTDRANESMEQGENLQKLVHIEYSVRGQGDLLQPGREFLKEGTLMRVRGKSRHPRHLFLMNDTLLYTHPQKDGKYRLKSSLPVANMKVSRPVMDKVPYALKIETPESCLTLSASSCAERDEWHYCLSRALPEDYKTQALAAFHHSVEIRERLGISLGERLPTLVPVTHAMMCMNCGCDFSLTVRRHHCHACGKIVCRNCSRNKYPLKCLKNRMAKVCDGCFRELKLRNGPVPGSMRERPVSMSFPLSSSRFSSGSALSSVFQSISPSTFKKQKKVPSALSEVAASGEGSAISGYLSRCKSGKRRWKKLWLVIKGKVLYTYLASEDKVAMESIPLLGFTIAPEKEEGSSEVGPVFHLYHKKTLFYSFKAEDSNSAQRWMEAMEDASVL", "length": 1219 }, "evidence": [ { "id": "E1BQN2", "url": "https://omabrowser.org/oma/group/E1BQN2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BQN2", "url": "https://www.uniprot.org/uniprotkb/E1BQN2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BQN2", "url": "https://www.uniprot.org/uniprotkb/E1BQN2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BQN2", "url": "https://www.uniprot.org/uniprotkb/E1BQN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BQN2", "url": "https://www.uniprot.org/uniprotkb/E1BQN2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1BQN2", "url": "https://www.uniprot.org/uniprotkb/E1BQN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1208, "end_pos": 1210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1340, "end_pos": 1342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1400, "end_pos": 1402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1561, "end_pos": 1563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 805, "end_pos": 807, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 738 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1208, "end_pos": 1210 }, { "start_pos": 1340, "end_pos": 1342 }, { "start_pos": 1400, "end_pos": 1402 }, { "start_pos": 1561, "end_pos": 1563 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 652, "end_pos": 654 }, { "start_pos": 713, "end_pos": 715 }, { "start_pos": 720, "end_pos": 722 }, { "start_pos": 730, "end_pos": 732 }, { "start_pos": 770, "end_pos": 772 }, { "start_pos": 805, "end_pos": 807 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQQ7-1", "uniprot_ac": "E1BQQ7", "uniprot_id": "E1BQQ7_CHICK", "mass": { "chemical_mass": 33444.0, "monoisotopic_mass": 33444.0 }, "refseq": {}, "gene_names": [ { "name": "MMD2", "type": "recommended", "evidence": [ { "id": "E1BQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ] } ], "protein_names": [ { "name": "Monocyte to macrophage differentiation associated 2", "type": "synonym", "evidence": [ { "id": "E1BQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MMD2", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7", "locus": { "chromosome": "14", "start_pos": 4041580, "end_pos": 4052813, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021159", "url": "https://www.ensembl.org/id/ENSGALG00010021159" } ] } } ], "crossref": [ { "id": "E1BQQ7", "url": "https://alphafold.ebi.ac.uk/entry/E1BQQ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004530", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004530", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR004254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI14", "url": "https://www.orthodb.org/?gene=A0A8V0ZI14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQQ7", "url": "https://www.orthodb.org/?gene=E1BQQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20855:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20855:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03006", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03006", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZI14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQQ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLASGALDFQKTRYARFMNHRVPSNRRYQPTEYEHAANCATHAFWILPSILGSSILYVLSDDRWETISAWIYGFGLSSLFIVSTIFHTISWKKRHLRTVEHCLHMFDRMVIYFFIAASYAPWLNLRELGPWASHMRWIIWIMASVGTVYVFFFHERYKLVELVCYVIMGFFPALVILSMGRPPRAGGWRDFLLPGHGLLQKRWPHPLRPRHLAPLCGHWSWHPLLRHLEVPLPARRAGGQNVPIDALRTLHINGDMEGEQGGEPGPWAHPEATCCPLHGFDFKQIFLF", "length": 288, "header": "tr|E1BQQ7-1|E1BQQ7_CHICK Isoform 1 of Monocyte to macrophage differentiation associated 2 OS=Gallus gallus OX=9031 GN=MMD2 PE=3 SV=4 CANONICAL=E1BQQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI14-1", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7/entry#A0A8V0ZI14-1", "sequence": { "sequence": "MLASGALDFQKTRYARFMNHRVPSNRRYQPTEYEHAANCATHAFWILPSILGSSILYVLSDDRWETISAWIYGFGLSSLFIVSTIFHTISWKKRHLRTVEHCLHMFDRMVIYFFIAASYAPWLNLRELGPWASHMRWIIWIMASVGTVYVFFFHERPIGTASQSWWLAGFPTAWAWSSSKAMAASPSPTPSGTSLWPLELASITTPFGGTSTGPARWRPKRPDRRLKDTSHQWGHGRGAGRGARAVGSPRSHLLPPAWF", "length": 259, "header": "tr|A0A8V0ZI14-1|A0A8V0ZI14_CHICK Computationally mapped isoform of Monocyte to macrophage differentiation associated 2 OS=Gallus gallus OX=9031 GN=MMD2 PE=3 SV=1 CANONICAL=E1BQQ7-1" }, "locus": { "chromosome": "14", "start_pos": 4052548, "end_pos": 4043297, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051246.1", "url": "https://www.ensembl.org/id/ENSGALT00010051246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030437.1", "url": "https://www.ensembl.org/id/ENSGALP00010030437.1" } ] } }, { "isoform_ac": "E1BQQ7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7/entry#E1BQQ7-1", "sequence": { "sequence": "MLASGALDFQKTRYARFMNHRVPSNRRYQPTEYEHAANCATHAFWILPSILGSSILYVLSDDRWETISAWIYGFGLSSLFIVSTIFHTISWKKRHLRTVEHCLHMFDRMVIYFFIAASYAPWLNLRELGPWASHMRWIIWIMASVGTVYVFFFHERYKLVELVCYVIMGFFPALVILSMGRPPRAGGWRDFLLPGHGLLQKRWPHPLRPRHLAPLCGHWSWHPLLRHLEVPLPARRAGGQNVPIDALRTLHINGDMEGEQGGEPGPWAHPEATCCPLHGFDFKQIFLF", "length": 288, "header": "tr|E1BQQ7-1|E1BQQ7_CHICK Isoform 1 of Monocyte to macrophage differentiation associated 2 OS=Gallus gallus OX=9031 GN=MMD2 PE=3 SV=4 CANONICAL=E1BQQ7-1" }, "locus": { "chromosome": "14", "start_pos": 4052548, "end_pos": 4043272, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051243.1", "url": "https://www.ensembl.org/id/ENSGALT00010051243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030434.1", "url": "https://www.ensembl.org/id/ENSGALP00010030434.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of Ras protein signal transduction", "id": "GO:0046579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046579", "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "pmid": "" }, { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "E1BQQ7", "url": "https://www.uniprot.org/uniprotkb/E1BQQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQQ7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 288, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQQ7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQQ7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQR6-1", "uniprot_ac": "E1BQR6", "uniprot_id": "E1BQR6_CHICK", "mass": { "chemical_mass": 40072.0, "monoisotopic_mass": 40072.0 }, "refseq": { "ac": "XP_040538186", "name": "LIM and cysteine-rich domains protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538186" }, "gene_names": [ { "name": "LMCD1", "type": "recommended", "evidence": [ { "id": "E1BQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ] }, { "name": "LMCD1", "type": "synonym", "evidence": [ { "id": "XP_040538186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538186" } ] } ], "protein_names": [ { "name": "LIM and cysteine rich domains 1", "type": "synonym", "evidence": [ { "id": "E1BQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQR6/entry#names_and_taxonomy" } ] }, { "name": "LIM and cysteine-rich domains protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040538186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538186" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052584.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040538186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538186" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LMCD1", "url": "https://www.uniprot.org/uniprotkb/E1BQR6", "locus": { "chromosome": "12", "start_pos": 19434491, "end_pos": 19411207, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019441", "url": "https://www.ensembl.org/id/ENSGALG00010019441" } ] } } ], "crossref": [ { "id": "E1BQR6", "url": "https://alphafold.ebi.ac.uk/entry/E1BQR6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008349", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008349", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416113", "url": "https://www.ncbi.nlm.nih.gov/gene/416113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416113", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYCDSIR", "url": "https://omabrowser.org/oma/group/HYCDSIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BQR6", "url": "https://www.orthodb.org/?gene=E1BQR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5683826", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5683826", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040538186", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040538186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQR6-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSPGVQKMSMSQPQSGRGVPCLRCRGTCMGFEPHSWRKICKSCKCSQEDHCLSSDVEDDRKIGRLLSDSKYATLTARVKGGDGVRIYKRNRMIITNPIVSRKDPTFDTITYEWAPPGLTQKLAMQYMELIPKEMQPVAGTDGAYYRRRQLVRQLPVHDHDPSQCRGLAEGEAKLMEDFVKKYKAEALGVGEVALPGQAGNAKEEGKAKDAGSAAEKPPETTNGALESTPTVGLYRCETCKQAVPEDCPVVYADRAGYARLWHPACFVCCRCAEPLVDLIYFWKSGAAWCGRHYCESLRPRCAGCDEIIFSEEFQRAEGMAWHKKHFACLECETLLSGKAFSLDKGGLRCATCSRSKRL", "length": 360, "header": "tr|E1BQR6-1|E1BQR6_CHICK Isoform 1 of LIM and cysteine rich domains 1 OS=Gallus gallus OX=9031 GN=LMCD1 PE=1 SV=2 CANONICAL=E1BQR6-1" }, "isoforms": [ { "isoform_ac": "E1BQR6-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR6/entry#E1BQR6-1", "sequence": { "sequence": "MELSPGVQKMSMSQPQSGRGVPCLRCRGTCMGFEPHSWRKICKSCKCSQEDHCLSSDVEDDRKIGRLLSDSKYATLTARVKGGDGVRIYKRNRMIITNPIVSRKDPTFDTITYEWAPPGLTQKLAMQYMELIPKEMQPVAGTDGAYYRRRQLVRQLPVHDHDPSQCRGLAEGEAKLMEDFVKKYKAEALGVGEVALPGQAGNAKEEGKAKDAGSAAEKPPETTNGALESTPTVGLYRCETCKQAVPEDCPVVYADRAGYARLWHPACFVCCRCAEPLVDLIYFWKSGAAWCGRHYCESLRPRCAGCDEIIFSEEFQRAEGMAWHKKHFACLECETLLSGKAFSLDKGGLRCATCSRSKRL", "length": 360, "header": "tr|E1BQR6-1|E1BQR6_CHICK Isoform 1 of LIM and cysteine rich domains 1 OS=Gallus gallus OX=9031 GN=LMCD1 PE=1 SV=2 CANONICAL=E1BQR6-1" }, "locus": { "chromosome": "12", "start_pos": 19431205, "end_pos": 19411260, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046968.1", "url": "https://www.ensembl.org/id/ENSGALT00010046968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027917.1", "url": "https://www.ensembl.org/id/ENSGALP00010027917.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416113", "resource": "KEGG Pathway" }, { "id": "R-GGA-5683826", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5683826", "resource": "Reactome", "description": "Surfactant metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cardiac muscle hypertrophy", "id": "GO:0010611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010611", "evidence": [ { "database": "UniProtKB", "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ], "pmid": "" }, { "name": "positive regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070886", "evidence": [ { "database": "UniProtKB", "id": "E1BQR6", "url": "https://www.uniprot.org/uniprotkb/E1BQR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQR6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 360, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQR6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQR6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQT4-1", "uniprot_ac": "E1BQT4", "uniprot_id": "E1BQT4_CHICK", "mass": { "chemical_mass": 68230.0, "monoisotopic_mass": 68230.0 }, "refseq": { "ac": "XP_416378", "name": "sodium- and chloride-dependent betaine transporter isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416378" }, "gene_names": [ { "name": "SLC6A12", "type": "recommended", "evidence": [ { "id": "E1BQT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ] }, { "name": "SLC6A12", "type": "synonym", "evidence": [ { "id": "XP_416378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416378" } ] } ], "protein_names": [ { "name": "Transporter", "type": "recommended", "evidence": [ { "id": "E1BQT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQT4/entry#names_and_taxonomy" } ] }, { "name": "sodium- and chloride-dependent betaine transporter isoform X2", "type": "synonym", "evidence": [ { "id": "XP_416378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416378" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_416378.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416378" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC6A12", "url": "https://www.uniprot.org/uniprotkb/E1BQT4", "locus": { "chromosome": "1", "start_pos": 60208405, "end_pos": 60238006, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015929", "url": "https://www.ensembl.org/id/ENSGALG00010015929" } ] } } ], "crossref": [ { "id": "E1BQT4", "url": "https://alphafold.ebi.ac.uk/entry/E1BQT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019290", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019290", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11511", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11511", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418147", "url": "https://www.ncbi.nlm.nih.gov/gene/418147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418147", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVVCIGW", "url": "https://omabrowser.org/oma/group/EVVCIGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVV7", "url": "https://www.orthodb.org/?gene=A0A8V0YVV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQT4", "url": "https://www.orthodb.org/?gene=E1BQT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11616:SF118", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11616:SF118", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-352230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-888593", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-888593", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YVV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQT4-1", "url": "https://www.uniprot.org/uniprotkb/E1BQT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRATVKKAEPNGAIAAPEETKKEEMEERGQWSSKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYLIFLFTCGIPLFLLETALGQYTSQGGVTAWRKICPIFEGIGYSSQVIETYLNIYYIIILSWALFYLFSSFTTVLPWASCNNPWNSDLCVDFLNSSDWDNRTVPANATSPVVEFWEKRVLGLTDGIHKLGTVRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYAMLVILLVRGVTLPGAAEGIVFYLKPDVSRLADPQVWMDAGTQILFSYAICQGCLTALGSYNKYTNNCYRDCIMLCFLNSATSFVAGFAIFSVLGFMAREQGVPIAEVAESGPGLAFIAYPTAVTMMPVSQLWSCLFFLMLIFLGLDSQFVCVESMVTALIDMFPGVFRKKGRRELLILAIAVICYLLGLLLVTEGGMYIFQLFDYYAASGTCLLFLAIFEVICVGWVYGANRFYDNIEDMIGYRPWPLIKICWLVFTPGLCLAVFLFSLIKYAPLKYNNSYVYPPWGYVLGWLMALSSMVCIPLYIIFILLRTKGSLKQRLAQLISPAEDLPQPRKHVVALSEQKLKEQSPPVQEMLSITERETHF", "length": 607, "header": "tr|E1BQT4-1|E1BQT4_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A12 PE=1 SV=2 CANONICAL=E1BQT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YVV7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQT4/entry#A0A8V0YVV7-1", "sequence": { "sequence": "MTRATVKKAEPNGAIAAPEETKKEEMEERGQWSSKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYLIFLFTCGIPLFLLETALGQYTSQGGVTAWRKICPIFEGIGYSSQVIETYLNIYYIIILSWALFYLFSSFTTVLPWASCNNPWNSDLCVDFLNSSDWDNRTVPANATSPVVEFWEKRVLGLTDGIHKLGTVRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYAMLVILLVRGVTLPGAAEGIVFYLKPDVSRLADPQVWMDAGTQILFSYAICQGCLTALGSYNKYTNNCYSATSFVAGFAIFSVLGFMAREQGVPIAEVAESGPGLAFIAYPTAVTMMPVSQLWSCLFFLMLIFLGLDSQFVCVESMVTALIDMFPGVFRKKGRRELLILAIAVICYLLGLLLVTEGGMYIFQLFDYYAASGTCLLFLAIFEVICVGWVYGANRFYDNIEDMIGYRPWPLIKICWLVFTPGLCLAVFLFSLIKYAPLKYNNSYVYPPWGYVLGWLMALSSMVCIPLYIIFILLRTKGSLKQRLAQLISPAEDLPQPRKHVVALSEQKLKEQSPPVQEMLSITERETHF", "length": 597, "header": "tr|A0A8V0YVV7-1|A0A8V0YVV7_CHICK Computationally mapped isoform of Transporter OS=Gallus gallus OX=9031 GN=SLC6A12 PE=1 SV=1 CANONICAL=E1BQT4-1" }, "locus": { "chromosome": "1", "start_pos": 60238002, "end_pos": 60211575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038389.1", "url": "https://www.ensembl.org/id/ENSGALT00010038389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022197.1", "url": "https://www.ensembl.org/id/ENSGALP00010022197.1" } ] } }, { "isoform_ac": "E1BQT4-1", "url": "https://www.uniprot.org/uniprotkb/E1BQT4/entry#E1BQT4-1", "sequence": { "sequence": "MTRATVKKAEPNGAIAAPEETKKEEMEERGQWSSKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYLIFLFTCGIPLFLLETALGQYTSQGGVTAWRKICPIFEGIGYSSQVIETYLNIYYIIILSWALFYLFSSFTTVLPWASCNNPWNSDLCVDFLNSSDWDNRTVPANATSPVVEFWEKRVLGLTDGIHKLGTVRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYAMLVILLVRGVTLPGAAEGIVFYLKPDVSRLADPQVWMDAGTQILFSYAICQGCLTALGSYNKYTNNCYRDCIMLCFLNSATSFVAGFAIFSVLGFMAREQGVPIAEVAESGPGLAFIAYPTAVTMMPVSQLWSCLFFLMLIFLGLDSQFVCVESMVTALIDMFPGVFRKKGRRELLILAIAVICYLLGLLLVTEGGMYIFQLFDYYAASGTCLLFLAIFEVICVGWVYGANRFYDNIEDMIGYRPWPLIKICWLVFTPGLCLAVFLFSLIKYAPLKYNNSYVYPPWGYVLGWLMALSSMVCIPLYIIFILLRTKGSLKQRLAQLISPAEDLPQPRKHVVALSEQKLKEQSPPVQEMLSITERETHF", "length": 607, "header": "tr|E1BQT4-1|E1BQT4_CHICK Isoform 1 of Transporter OS=Gallus gallus OX=9031 GN=SLC6A12 PE=1 SV=2 CANONICAL=E1BQT4-1" }, "locus": { "chromosome": "1", "start_pos": 60238002, "end_pos": 60211575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038392.1", "url": "https://www.ensembl.org/id/ENSGALT00010038392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022200.1", "url": "https://www.ensembl.org/id/ENSGALP00010022200.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418147", "resource": "KEGG Pathway" }, { "id": "R-GGA-352230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-352230", "resource": "Reactome", "description": "Amino acid transport across the plasma membrane" }, { "id": "R-GGA-888593", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-888593", "resource": "Reactome", "description": "Reuptake of GABA" } ], "orthologs": [ { "uniprot_canonical_ac": "P31651-1", "protein_name": "Sodium- and chloride-dependent betaine transporter", "gene_name": "Slc6a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRKVAVHEDGYPVVSWVPEEGEMMDQKGKDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTEHCVDFLNHSSARGVSSSENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSILGFMSQEQGIPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLLFLGLDSQFVCMECLVTASMDMFPQQLRKSGRRDVLILAISVLCYLMGLLLVTEGGMYIFQLFDYYASSGICLLFLSLFEVICIGWVYGADRFYDNVEDMIGYRPWPLVKISWLFLTPGLCLATFFFSLSKYTPLKYNNVYMYPSWGYSIGWLLAFSSMACVPLFIIITFLKTQGSFKKRLRRLITPDPSLPQPGRRPPQDGSSAQNCSSSPAKQELIAWEKETHL", "length": 614 }, "evidence": [ { "id": "E1BQT4", "url": "https://omabrowser.org/oma/group/E1BQT4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48056-1", "protein_name": "Sodium- and chloride-dependent betaine transporter", "gene_name": "Slc6a12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRKVTVHEDGCPVVSWVPEEGEMMDQKDKDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTEHCVDFLNYSSTRAASYSENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSILGFMAQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFLMLLFLGLDSQFVCMECLVTASMDMFPQQLRKRGRRELLILAVAIVCYLMGLLLVTEGGMYIFQLFDYYASSGICLLFLSLFEVICIGWVYGADRFYDNVEDMIGYRPWPLVKISWLFLTPGLCLATFFFSLSKYTPLKYNNVYIYPSWGYSIGWLLAFSSMACVPLFIIITLLKTQGSFKKRLQRLITPDPSLPQPGRRSPQDGSSAQNCSTSPVKQELIAWEKETHL", "length": 614 }, "evidence": [ { "id": "E1BQT4", "url": "https://omabrowser.org/oma/group/E1BQT4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48065-1", "protein_name": "Sodium- and chloride-dependent betaine transporter", "gene_name": "SLC6A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSPTREGLIAGEKETHL", "length": 614 }, "evidence": [ { "id": "E1BQT4", "url": "https://omabrowser.org/oma/group/E1BQT4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "gamma-aminobutyric acid:sodium:chloride symporter activity", "id": "GO:0005332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005332", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" }, { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "E1BQT4", "url": "https://www.uniprot.org/uniprotkb/E1BQT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQT4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 607, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQT4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQT4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQU3-1", "uniprot_ac": "E1BQU3", "uniprot_id": "E1BQU3_CHICK", "mass": { "chemical_mass": 15757.0, "monoisotopic_mass": 15757.0 }, "refseq": { "ac": "NP_001186406", "name": "transmembrane protein 60", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186406" }, "gene_names": [ { "name": "TMEM60", "type": "recommended", "evidence": [ { "id": "E1BQU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQU3" } ] }, { "name": "C7orf35", "type": "synonym", "evidence": [ { "id": "NP_001186406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186406" } ] }, { "name": "TMEM60", "type": "synonym", "evidence": [ { "id": "NP_001186406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186406" } ] } ], "protein_names": [ { "name": "Transmembrane protein 60", "type": "synonym", "evidence": [ { "id": "E1BQU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQU3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 60", "type": "synonym", "evidence": [ { "id": "NP_001186406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186406" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU398554.1, BU423807.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 9, 2010 this sequence version replaced XP_415972.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186406" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQU3", "url": "https://www.uniprot.org/uniprotkb/E1BQU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM60", "url": "https://www.uniprot.org/uniprotkb/E1BQU3", "locus": { "chromosome": "1", "start_pos": 12723576, "end_pos": 12702109, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009386", "url": "https://www.ensembl.org/id/ENSGALG00010009386" } ] } } ], "crossref": [ { "id": "ENSGALG00000008330", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008330", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417727", "url": "https://www.ncbi.nlm.nih.gov/gene/417727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417727", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTHWNWF", "url": "https://omabrowser.org/oma/group/RTHWNWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BQU3", "url": "https://www.orthodb.org/?gene=E1BQU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10269", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10269", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186406", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BQU3", "url": "https://www.uniprot.org/uniprotkb/E1BQU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BQU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRNGSQNIKKKTWYLIAMLLKLAFCLALCAKLQQFTTMKLAYVFIPLWALLIGGMIELGYNIFYVRRD", "length": 134, "header": "tr|E1BQU3-1|E1BQU3_CHICK Isoform 1 of Transmembrane protein 60 OS=Gallus gallus OX=9031 GN=TMEM60 PE=4 SV=1 CANONICAL=E1BQU3-1" }, "isoforms": [ { "isoform_ac": "E1BQU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BQU3/entry#E1BQU3-1", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRNGSQNIKKKTWYLIAMLLKLAFCLALCAKLQQFTTMKLAYVFIPLWALLIGGMIELGYNIFYVRRD", "length": 134, "header": "tr|E1BQU3-1|E1BQU3_CHICK Isoform 1 of Transmembrane protein 60 OS=Gallus gallus OX=9031 GN=TMEM60 PE=4 SV=1 CANONICAL=E1BQU3-1" }, "locus": { "chromosome": "1", "start_pos": 12706465, "end_pos": 12706064, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022397.1", "url": "https://www.ensembl.org/id/ENSGALT00010022397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012889.1", "url": "https://www.ensembl.org/id/ENSGALP00010012889.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417727", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IGV6-1", "protein_name": "Transmembrane protein 60", "gene_name": "Tmem60", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD", "length": 133 }, "evidence": [ { "id": "E1BQU3", "url": "https://omabrowser.org/oma/group/E1BQU3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A287AK80-1", "protein_name": "Transmembrane protein 60", "gene_name": "TMEM60", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALIELGYNVFFVRD", "length": 133 }, "evidence": [ { "id": "E1BQU3", "url": "https://omabrowser.org/oma/group/E1BQU3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZUD9-1", "protein_name": "Transmembrane protein 60", "gene_name": "Tmem60", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEHFTTINLSYVFIPLWALLAGALTELGYNVFFVRD", "length": 133 }, "evidence": [ { "id": "E1BQU3", "url": "https://omabrowser.org/oma/group/E1BQU3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K174-1", "protein_name": "Transmembrane protein 60", "gene_name": "Tmem60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD", "length": 133 }, "evidence": [ { "id": "E1BQU3", "url": "https://omabrowser.org/oma/group/E1BQU3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2L4-1", "protein_name": "Transmembrane protein 60", "gene_name": "TMEM60", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVLLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD", "length": 133 }, "evidence": [ { "id": "E1BQU3", "url": "https://omabrowser.org/oma/group/E1BQU3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQU8-1", "uniprot_ac": "E1BQU8", "uniprot_id": "E1BQU8_CHICK", "mass": { "chemical_mass": 58191.0, "monoisotopic_mass": 58191.0 }, "refseq": { "ac": "XP_425129", "name": "potassium voltage-gated channel subfamily G member 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425129" }, "gene_names": [ { "name": "KCNG4", "type": "recommended", "evidence": [ { "id": "E1BQU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ] }, { "name": "KCNG4", "type": "synonym", "evidence": [ { "id": "XP_425129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425129" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel modifier subfamily G member 4", "type": "synonym", "evidence": [ { "id": "E1BQU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQU8/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily G member 4", "type": "synonym", "evidence": [ { "id": "XP_425129", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425129" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_425129.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425129" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNG4", "url": "https://www.uniprot.org/uniprotkb/E1BQU8", "locus": { "chromosome": "11", "start_pos": 16304204, "end_pos": 16321498, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007585", "url": "https://www.ensembl.org/id/ENSGALG00010007585" } ] } } ], "crossref": [ { "id": "E1BQU8", "url": "https://alphafold.ebi.ac.uk/entry/E1BQU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005502", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005502", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18423", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18423", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395901", "url": "https://www.ncbi.nlm.nih.gov/gene/395901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395901", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQARNKC", "url": "https://omabrowser.org/oma/group/VQARNKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BQU8", "url": "https://www.orthodb.org/?gene=E1BQU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_425129", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425129", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BQU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPILSGGSDQDYSNISYASCNSLSHFFPVSVETPSVKGVHYQRARRIYRPDQASAVDLKTEIMINVGGIKYLLPWSTLDEFPLTRLSKLKFCSSYEEIIQLCDDYDEDTREFFFDRNPNAFGMIVSFLAAGKLMLLRDMCALSFQEELRYWGIEESNLENCCFRKLFQKLQELAEVRKEEELRRSKEAACVLDEKTKFGQFMNRLRDMVENPQSGLPGKVFACLSILFVATTAISLCVSTMPDLRAEEDRGECSQKCYYIFVIETICVAWFSLEFCLRFIQARSKCQFFKGPLNIIDFLAISPYYVSLILAEDDSSETDDKPSSNTYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLCVAVTLFSPLVYLAENESGKVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMSFPATSIFHTFSHSYSELRKEHERLQSRLNRVKNANHSGESDTFNETDSLILEEPASPIKYIYTGN", "length": 511, "header": "tr|E1BQU8-1|E1BQU8_CHICK Isoform 1 of Potassium voltage-gated channel modifier subfamily G member 4 OS=Gallus gallus OX=9031 GN=KCNG4 PE=4 SV=3 CANONICAL=E1BQU8-1" }, "isoforms": [ { "isoform_ac": "E1BQU8-1", "url": "https://www.uniprot.org/uniprotkb/E1BQU8/entry#E1BQU8-1", "sequence": { "sequence": "MPILSGGSDQDYSNISYASCNSLSHFFPVSVETPSVKGVHYQRARRIYRPDQASAVDLKTEIMINVGGIKYLLPWSTLDEFPLTRLSKLKFCSSYEEIIQLCDDYDEDTREFFFDRNPNAFGMIVSFLAAGKLMLLRDMCALSFQEELRYWGIEESNLENCCFRKLFQKLQELAEVRKEEELRRSKEAACVLDEKTKFGQFMNRLRDMVENPQSGLPGKVFACLSILFVATTAISLCVSTMPDLRAEEDRGECSQKCYYIFVIETICVAWFSLEFCLRFIQARSKCQFFKGPLNIIDFLAISPYYVSLILAEDDSSETDDKPSSNTYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLCVAVTLFSPLVYLAENESGKVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMSFPATSIFHTFSHSYSELRKEHERLQSRLNRVKNANHSGESDTFNETDSLILEEPASPIKYIYTGN", "length": 511, "header": "tr|E1BQU8-1|E1BQU8_CHICK Isoform 1 of Potassium voltage-gated channel modifier subfamily G member 4 OS=Gallus gallus OX=9031 GN=KCNG4 PE=4 SV=3 CANONICAL=E1BQU8-1" }, "locus": { "chromosome": "11", "start_pos": 16320214, "end_pos": 16304939, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018062.1", "url": "https://www.ensembl.org/id/ENSGALT00010018062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009948.1", "url": "https://www.ensembl.org/id/ENSGALP00010009948.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395901", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395901", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AD66-1", "protein_name": "Potassium voltage-gated channel modifier subfamily G member 4", "gene_name": "Kcng4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPMSSRGRDLHPGHHHFGPCSPLTQFWPGPEPQSVKGLYYRRARKVSTLDASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDYDENSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEEANLERCCLRKLLKKLEEAAELRREEAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEDKGECARKCYYIFVVETICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLLLFLGVAVTLFSPLVYVAENESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQVQARLRRLQNNNSASERELLSDVDDLAPEDLTSPGRYM", "length": 506 }, "evidence": [ { "id": "E1BQU8", "url": "https://omabrowser.org/oma/group/E1BQU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GRX8-1", "protein_name": "Potassium voltage-gated channel subfamily G member 4", "gene_name": "Kcng4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPMSSRDLPPGHHHFGSCSPLSQLWPGPEPPSVKGLYYSRARKVGTLDASPEADLKKEILVNVGGRRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDYDENNQEFFFDRSPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEEANLERCCLRKLMKKLEEVAELRREEAVQRQQQRQACHSEVHTSRWARGMNQLREMVEDPQSGLPGKVFACLSILFVATTAVSLCVSTMPDFRAEEDKGECTRKCYYIFVVETICVAWFSLEFCLRFAQARNKCQFFRGPLNVIDILAISPYYVSLVVSEESSEAGERLSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLLLFLGVAVTLFSPLVYVAENESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQIQARLRRLQNTNSASERELLSDVDDLVPEGLASPIRYV", "length": 505 }, "evidence": [ { "id": "E1BQU8", "url": "https://omabrowser.org/oma/group/E1BQU8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q80XM3-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG4", "gene_name": "Kcng4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPMSSRDRDLHPGHHHFGSCSPLSQLWPGPEPKSVKGLYYSRARKVGNQDASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSHEEITQLCDDYDEDSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEETNLERCCLRKLLKKLEEAAELRREEAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEGKGECTRKCYYIFVVESICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSSSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLMLFLAVAVTLFSPLVYVAENESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQVQARLRRLQNTNSASERELLSDVDDLVPEGLTSPGRYM", "length": 506 }, "evidence": [ { "id": "E1BQU8", "url": "https://omabrowser.org/oma/group/E1BQU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDN1-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG4", "gene_name": "KCNG4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPMPSRDGGLHPRHHHYGSHSPWSQLLSSPMETPSIKGLYYRRVRKVGALDASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQARLRHLQNTGPASECELLDPHVASEHELMNDVNDLILEGPALPIMHM", "length": 519 }, "evidence": [ { "id": "E1BQU8", "url": "https://omabrowser.org/oma/group/E1BQU8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of potassium ion transmembrane transport", "id": "GO:1901379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901379", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" }, { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "E1BQU8", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BQU8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 511, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BQU8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BQU8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 219, "end_pos": 462, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BQU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQU8" }, { "id": "PF02214", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel tetramerisation-type BTB", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 161, "start_aa": "Ile", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BRV0-1", "uniprot_ac": "E1BRV0", "uniprot_id": "E1BRV0_CHICK", "mass": { "chemical_mass": 66730.0, "monoisotopic_mass": 66730.0 }, "refseq": { "ac": "NP_001376469", "name": "interleukin-22 receptor subunit alpha-1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376469" }, "gene_names": [ { "name": "IL22RA1", "type": "recommended", "evidence": [ { "id": "E1BRV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRV0" } ] }, { "name": "IL22RA1", "type": "synonym", "evidence": [ { "id": "NP_001376469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376469" } ] } ], "protein_names": [ { "name": "Interleukin-22 receptor subunit alpha-1", "type": "recommended", "evidence": [ { "id": "E1BRV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRV0/entry#names_and_taxonomy" } ] }, { "name": "interleukin 22 receptor, alpha 1", "type": "synonym", "evidence": [ { "id": "NP_001376469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376469" } ] }, { "name": "interleukin-22 receptor subunit alpha-1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001376469", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376469" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888525.310599.1, SRR12888488.103341.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992692 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000339.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376469" } ] }, { "annotation": "Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.", "evidence": [ { "database": "UniProtKB", "id": "E1BRV0", "url": "https://www.uniprot.org/uniprotkb/E1BRV0#function" }, { "database": "UniProtKB", "id": "ARBA00055421", "url": "https://www.uniprot.org/uniprotkb/ARBA00055421#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BRV0", "url": "https://www.uniprot.org/uniprotkb/E1BRV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL22RA1", "url": "https://www.uniprot.org/uniprotkb/E1BRV0", "locus": { "chromosome": "23", "start_pos": 6024655, "end_pos": 6032924, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015798", "url": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WLAKEGC", "url": "https://omabrowser.org/oma/group/WLAKEGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BRV0", "url": "https://www.orthodb.org/?gene=E1BRV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20859:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20859:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01108", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01108", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": 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"database": "Ensembl Peptide", "id": "ENSGALP00010021945.1", "url": "https://www.ensembl.org/id/ENSGALP00010021945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8854691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854691", "resource": "Reactome", "description": "Interleukin-20 family signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BRV0", "url": "https://www.uniprot.org/uniprotkb/E1BRV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "E1BRV0", "url": "https://www.uniprot.org/uniprotkb/E1BRV0" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "E1BRV0", "url": "https://www.uniprot.org/uniprotkb/E1BRV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "interleukin-22 receptor activity", "id": "GO:0042018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042018", "evidence": [ { "database": "UniProtKB", "id": "E1BRV0", "url": "https://www.uniprot.org/uniprotkb/E1BRV0" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "E1BRV0", "url": "https://www.uniprot.org/uniprotkb/E1BRV0" } ], "pmid": "" }, { "name": "interleukin-20 binding", "id": "GO:0042015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042015", 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BRV2-1", "uniprot_ac": "E1BRV2", "uniprot_id": "E1BRV2_CHICK", "mass": { "chemical_mass": 17648.0, "monoisotopic_mass": 17648.0 }, "refseq": { "ac": "NP_001264971", "name": "large ribosomal subunit protein bL20m", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264971" }, "gene_names": [ { "name": "MRPL20", "type": "recommended", "evidence": [ { "id": "E1BRV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRV2" } ] }, { "name": "MRPL20", "type": "synonym", "evidence": [ { "id": "NP_001264971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264971" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein bL20m", "type": "recommended", "evidence": [ { "id": "E1BRV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRV2/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L20, mitochondrial", "type": "synonym", "evidence": [ { "id": "E1BRV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRV2/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein bL20m", "type": "synonym", "evidence": [ { "id": "NP_001264971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264971" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU113819.1, BU254813.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000329.1. On May 5, 2013 this sequence version replaced XP_001234297.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264971" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BRV2", "url": "https://www.uniprot.org/uniprotkb/E1BRV2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL20", "url": "https://www.uniprot.org/uniprotkb/E1BRV2", "locus": { "chromosome": "21", "start_pos": 2207138, "end_pos": 2204196, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017739", "url": "https://www.ensembl.org/id/ENSGALG00010017739" } ] } } ], "crossref": [ { "id": "E1BRV2", "url": "https://alphafold.ebi.ac.uk/entry/E1BRV2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001542", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001542", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07026", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07026", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770979", "url": "https://www.ncbi.nlm.nih.gov/gene/770979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770979", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770979", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GRRKNVW", "url": "https://omabrowser.org/oma/group/GRRKNVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BRV2", "url": "https://www.orthodb.org/?gene=E1BRV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10986", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10986", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264971", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BRV2", "url": "https://www.uniprot.org/uniprotkb/E1BRV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BRV2-1", "url": "https://www.uniprot.org/uniprotkb/E1BRV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLSVPLWLRSRLTDRFWRVQEVLKYARHFRGRKNRCYKLAVRNVQRAFVKSTRARKQKKRFLRALWITRIEAASLEHGLKYSAFISNLFKTQVELNRKMIADLAIYEPKTFKSLAALAQRRRQEGFLAALGDGKEPEGIFSRIVHHY", "length": 149, "header": "tr|E1BRV2-1|E1BRV2_CHICK Isoform 1 of Large ribosomal subunit protein bL20m OS=Gallus gallus OX=9031 GN=MRPL20 PE=1 SV=1 CANONICAL=E1BRV2-1" }, "isoforms": [ { "isoform_ac": "E1BRV2-1", "url": "https://www.uniprot.org/uniprotkb/E1BRV2/entry#E1BRV2-1", "sequence": { "sequence": "MVLLSVPLWLRSRLTDRFWRVQEVLKYARHFRGRKNRCYKLAVRNVQRAFVKSTRARKQKKRFLRALWITRIEAASLEHGLKYSAFISNLFKTQVELNRKMIADLAIYEPKTFKSLAALAQRRRQEGFLAALGDGKEPEGIFSRIVHHY", "length": 149, "header": "tr|E1BRV2-1|E1BRV2_CHICK Isoform 1 of Large ribosomal subunit protein bL20m OS=Gallus gallus OX=9031 GN=MRPL20 PE=1 SV=1 CANONICAL=E1BRV2-1" }, "locus": { "chromosome": "21", "start_pos": 2206868, "end_pos": 2204577, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042884.1", "url": "https://www.ensembl.org/id/ENSGALT00010042884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025374.1", "url": "https://www.ensembl.org/id/ENSGALP00010025374.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770979", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770979", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZU56-1", "protein_name": "Large ribosomal subunit protein bL20m", "gene_name": "MRPL20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVFLTVPLWLRSRVTDRYWRVQEVLKHARHFRGRKNRCYRLAVRAVTRAFVKCTRARRLKKRSLRTLWINRITAASQEHGLKYPAFIINLIKCQVELNRKVLADLAIYEPKTFKSLAALAKRRREEGFAAALGDGKEPDGIFSRVVQHR", "length": 149 }, "evidence": [ { "id": "E1BRV2", "url": "https://omabrowser.org/oma/group/E1BRV2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I429-1", "protein_name": "Large ribosomal subunit protein bL20m", "gene_name": "Mrpl20", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVFLTTRLWLRNRITDRFWRVQEVLKHARHFKGRKNRCYRLAVRAVTRAFVKCTQARRLKKRNLRTLWINRITAASQEHGLQYPAFIANLIKCQVELNRKVLVDLAIYEPKTFKSLAALAKRRQQEGFAAALGDGKEPEGIFSRVVQYH", "length": 149 }, "evidence": [ { "id": "E1BRV2", "url": "https://omabrowser.org/oma/group/E1BRV2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q556W7-1", "protein_name": "50S ribosomal protein L20", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNIDKVFKLAKGFFGRSKNCKSLARERVEKGLEYNYVSRKLKKRDFRKMWIERINAGARQHEMTYSDFQRGLIASGVEINRKILSELAVSEPFSFKVLVDHSKNTVSNLHPKSYIPLDQPKN", "length": 122 }, "evidence": [ { "id": "E1BRV2", "url": "https://omabrowser.org/oma/group/E1BRV2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9BYC9-1", "protein_name": "Large ribosomal subunit protein bL20m", "gene_name": "MRPL20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVFLTAQLWLRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYLKKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYEPKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH", "length": 149 }, "evidence": [ { "id": "E1BRV2", "url": "https://omabrowser.org/oma/group/E1BRV2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQL4-1", "protein_name": "Large ribosomal subunit protein bL20m", "gene_name": "Mrpl20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVFLTTRLWLRNRLTDRYWRVQEVLKHAQHFRGRKNRCYRLAVRAVTRAFVKCTKARRLKKRNLRTLWINRITAASQEHGLKYPAFIVNLIKCQVELNRKVLVDLAIYEPKTFKSLAALAKRRQQEGFAAALGDGKEPEGIFSRVVQYH", "length": 149 }, "evidence": [ { "id": "E1BRV2", "url": "https://omabrowser.org/oma/group/E1BRV2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VU36-1", "protein_name": "Large ribosomal subunit protein bL20m", "gene_name": "mRpL20", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVFLNLPLLVRSRGPDEFWRKRRIFKLAAHYRSRTRNVYSFAIRSVHRALAYATKGRKLKKLDMAQLWSTRVEAGCQQYGVGLETFKEGLARSDILLNKKVLSDLAIWEPRSFEALVKISRERAAVEGMPDIKRRSAFNQVYGLSNLKLD", "length": 150 }, "evidence": [ { "id": "E1BRV2", "url": "https://omabrowser.org/oma/group/E1BRV2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "E1BRV2", "url": "https://www.uniprot.org/uniprotkb/E1BRV2" } ], "pmid": "" }, { "name": "mitochondrial ribosome", "id": "GO:0005761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005761", "evidence": [ { "database": "UniProtKB", "id": "E1BRV2", "url": "https://www.uniprot.org/uniprotkb/E1BRV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1BRV2", "url": "https://www.uniprot.org/uniprotkb/E1BRV2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "E1BRV2", "url": "https://www.uniprot.org/uniprotkb/E1BRV2" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1BRV2", "url": "https://www.uniprot.org/uniprotkb/E1BRV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BRV2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 149, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BRV2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BRV2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BS45-1", "uniprot_ac": "E1BS45", "uniprot_id": "E1BS45_CHICK", "mass": { "chemical_mass": 15495.0, "monoisotopic_mass": 15495.0 }, "refseq": { "ac": "XP_003640728", "name": "coiled-coil domain-containing protein 126", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640728" }, "gene_names": [ { "name": "CCDC126", "type": "recommended", "evidence": [ { "id": "E1BS45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS45" } ] }, { "name": "CCDC126", "type": "synonym", "evidence": [ { "id": "XP_003640728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640728" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 126", "type": "synonym", "evidence": [ { "id": "E1BS45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS45/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 126", "type": "synonym", "evidence": [ { "id": "XP_003640728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640728" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640728" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BS45", "url": "https://www.uniprot.org/uniprotkb/E1BS45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC126", "url": "https://www.uniprot.org/uniprotkb/E1BS45", "locus": { "chromosome": "2", "start_pos": 31227921, "end_pos": 31213305, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001414", "url": "https://www.ensembl.org/id/ENSGALG00010001414" } ] } } ], "crossref": [ { "id": "E1BS45", "url": "https://alphafold.ebi.ac.uk/entry/E1BS45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010976", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010976", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420619", "url": "https://www.ncbi.nlm.nih.gov/gene/420619", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420619", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420619", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VNASAHN", "url": "https://omabrowser.org/oma/group/VNASAHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BS45", "url": "https://www.orthodb.org/?gene=E1BS45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46941:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46941:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BS45", "url": "https://www.uniprot.org/uniprotkb/E1BS45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BS45-1", "url": "https://www.uniprot.org/uniprotkb/E1BS45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLTFSRKNMSQKLSMFLLVFGIIWGLMLLRYTFQYPRRQSSAELRGQILDLSKRYVKALAEENKNLMNGGSGASVAGYADLKRTIAVLLDDILQRLVKLENKVDYIIVNGSATNTTNGTSNQVSVNSSKRAKAAGNIR", "length": 139, "header": "tr|E1BS45-1|E1BS45_CHICK Isoform 1 of Coiled-coil domain containing 126 OS=Gallus gallus OX=9031 GN=CCDC126 PE=1 SV=1 CANONICAL=E1BS45-1" }, "isoforms": [ { "isoform_ac": "E1BS45-1", "url": "https://www.uniprot.org/uniprotkb/E1BS45/entry#E1BS45-1", "sequence": { "sequence": "MFLTFSRKNMSQKLSMFLLVFGIIWGLMLLRYTFQYPRRQSSAELRGQILDLSKRYVKALAEENKNLMNGGSGASVAGYADLKRTIAVLLDDILQRLVKLENKVDYIIVNGSATNTTNGTSNQVSVNSSKRAKAAGNIR", "length": 139, "header": "tr|E1BS45-1|E1BS45_CHICK Isoform 1 of Coiled-coil domain containing 126 OS=Gallus gallus OX=9031 GN=CCDC126 PE=1 SV=1 CANONICAL=E1BS45-1" }, "locus": { "chromosome": "2", "start_pos": 31224243, "end_pos": 31223135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003245.1", "url": "https://www.ensembl.org/id/ENSGALT00010003245.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001702.1", "url": "https://www.ensembl.org/id/ENSGALP00010001702.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420619", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420619", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZT8-1", "protein_name": "Coiled-coil domain containing 126", "gene_name": "CCDC126", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIFTISRKNMSQKLSLLLLIFGLIWGLMLLHYTFQQPRHQSSVKLREQILDLSKRYVKALAEENKNTVDVENGASMAGYADLKRTIAVLLDDILQRLVKLENKVDYIVVNGSATNTTNGTSGSLVPVTTNKRINASGSIR", "length": 140 }, "evidence": [ { "id": "E1BS45", "url": "https://omabrowser.org/oma/group/E1BS45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7GLB1-1", "protein_name": "Coiled-coil domain-containing protein 126 isoform X1", "gene_name": "Ccdc126", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSFTISRKNMSQKLSFLLLVFGLIWGLMLLHYTFQQPRHQSSVKLREQILDLSKRYVKALAEESKSMVDVDSGASMAGYGKNRADLKRTIAVLLDDILQRLVKLENKVDYIVVNGSATNTTNGTSGNLVPVTTNKRTSASGSVR", "length": 144 }, "evidence": [ { "id": "E1BS45", "url": "https://omabrowser.org/oma/group/E1BS45/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2VE00-1", "protein_name": "Coiled-coil domain-containing protein 126", "gene_name": "CCDC126", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVFTISRKSMSQKLSLLLLVFGLLWGLMLLHYIFQRPRHQSSVKLREQILDLSKKYVKALAEENKNTMDVENGASMAGYADLRRTIAVLLDDILQRLVKLENKVDYIVVNGSAASTTSGTSGNPVPLTTNKRVKASGSIR", "length": 140 }, "evidence": [ { "id": "E1BS45", "url": "https://omabrowser.org/oma/group/E1BS45/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B5DEZ3-1", "protein_name": "Coiled-coil domain containing 126", "gene_name": "Ccdc126", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFRTISRKNMSQKLSFLLLVFGLIWGLMLLHYTLQQPQRQSSVKLREQILDLSKRYVKALAEESRSTADVDGGASMAGYADLKRTIAVLLDDILQRLVKLESKVDYIVVNGSATNTTNGTNGNLVPVTTNKRTSVSGSVR", "length": 140 }, "evidence": [ { "id": "E1BS45", "url": "https://omabrowser.org/oma/group/E1BS45/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BIS8-1", "protein_name": "Coiled-coil domain-containing protein 126", "gene_name": "Ccdc126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRTISRKNMSQKLSFLLLVFGLIWGLMLLHYTLQQPRRQSSVKLREQILDLSKRYVKALAEESRSTADVDSGASMAGYADLKRTIAVLLDDILQRLVKLESKVDYIVVNGSATNTTNGTNGNLVPVTTNKRTSVSGSVR", "length": 140 }, "evidence": [ { "id": "E1BS45", "url": "https://omabrowser.org/oma/group/E1BS45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EE4-1", "protein_name": "Coiled-coil domain-containing protein 126", "gene_name": "CCDC126", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFFTISRKNMSQKLSLLLLVFGLIWGLMLLHYTFQQPRHQSSVKLREQILDLSKRYVKALAEENKNTVDVENGASMAGYADLKRTIAVLLDDILQRLVKLENKVDYIVVNGSAANTTNGTSGNLVPVTTNKRTNVSGSIR", "length": 140 }, "evidence": [ { "id": "E1BS45", "url": "https://omabrowser.org/oma/group/E1BS45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BS45", "url": "https://www.uniprot.org/uniprotkb/E1BS45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BS45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 139, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BS45-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BS45" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BS45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS45" }, { "id": "PF15027", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGT5A-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 137, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 115, "end_pos": 117 }, { "start_pos": 118, "end_pos": 120 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BS52-1", "uniprot_ac": "E1BS52", "uniprot_id": "E1BS52_CHICK", "mass": { "chemical_mass": 17271.0, "monoisotopic_mass": 17271.0 }, "refseq": { "ac": "XP_001234382", "name": "protein FAM163A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234382" }, "gene_names": [ { "name": "FAM163A", "type": "recommended", "evidence": [ { "id": "E1BS52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS52" } ] }, { "name": "FAM163A", "type": "synonym", "evidence": [ { "id": "XP_001234382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234382" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 163 member A", "type": "synonym", "evidence": [ { "id": "E1BS52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS52/entry#names_and_taxonomy" } ] }, { "name": "protein FAM163A", "type": "synonym", "evidence": [ { "id": "XP_001234382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234382" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234382" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BS52", "url": "https://www.uniprot.org/uniprotkb/E1BS52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM163A", "url": "https://www.uniprot.org/uniprotkb/E1BS52", "locus": { "chromosome": "8", "start_pos": 6106219, "end_pos": 6113752, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010930", "url": "https://www.ensembl.org/id/ENSGALG00010010930" } ] } } ], "crossref": [ { "id": "E1BS52", "url": "https://alphafold.ebi.ac.uk/entry/E1BS52", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000020984", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000020984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "771080", "url": "https://www.ncbi.nlm.nih.gov/gene/771080", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771080", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771080", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGQPCGV", "url": "https://omabrowser.org/oma/group/CGQPCGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BS52", "url": "https://www.orthodb.org/?gene=E1BS52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31914:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31914:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001234382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234382", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BS52", "url": "https://www.uniprot.org/uniprotkb/E1BS52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BS52-1", "url": "https://www.uniprot.org/uniprotkb/E1BS52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDDPNEEEEEEEEEEEESDLPTHSHPGTCNACSSRMADGQGSPTPIPELNQHGAHPRCPTCSPYGSPFYIRTPDMVRNGGERVAYAPACYPEMGPPVGLQGFPLSRHGLREGFPPSRAISTEV", "length": 159, "header": "tr|E1BS52-1|E1BS52_CHICK Isoform 1 of Family with sequence similarity 163 member A OS=Gallus gallus OX=9031 GN=FAM163A PE=3 SV=1 CANONICAL=E1BS52-1" }, "isoforms": [ { "isoform_ac": "E1BS52-1", "url": "https://www.uniprot.org/uniprotkb/E1BS52/entry#E1BS52-1", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDDPNEEEEEEEEEEEESDLPTHSHPGTCNACSSRMADGQGSPTPIPELNQHGAHPRCPTCSPYGSPFYIRTPDMVRNGGERVAYAPACYPEMGPPVGLQGFPLSRHGLREGFPPSRAISTEV", "length": 159, "header": "tr|E1BS52-1|E1BS52_CHICK Isoform 1 of Family with sequence similarity 163 member A OS=Gallus gallus OX=9031 GN=FAM163A PE=3 SV=1 CANONICAL=E1BS52-1" }, "locus": { "chromosome": "8", "start_pos": 6109660, "end_pos": 6108465, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026170.1", "url": "https://www.ensembl.org/id/ENSGALT00010026170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014794.1", "url": "https://www.ensembl.org/id/ENSGALP00010014794.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771080", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771080", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AIB4-1", "protein_name": "Family with sequence similarity 163 member A", "gene_name": "FAM163A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSRAEDADDEEEEHDLPTHPRGPPCNACSSQALDGQGGLAPLPSEPCGQPCGVAASHCTTCSPYSSPFYIRTADMVPNGGGGERLPFAPTYYKEGGPPSLKVAAPQSYPVTWPGSGREAFTNPRAISTDV", "length": 166 }, "evidence": [ { "id": "E1BS52", "url": "https://omabrowser.org/oma/group/E1BS52/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SU95-1", "protein_name": "Family with sequence similarity 163 member A", "gene_name": "FAM163A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSRAEDADEEGEEEHDLPTHPRGPACNACSSQALDGRGSLAPVPGEPCGQPCRVAAGHCTACSPYSSPFYIRTADMVPNGGGGERLSFAPTYYKEGGPPSLQVAAPQSYPVTWPGSGREAFTNPRAISTDV", "length": 167 }, "evidence": [ { "id": "E1BS52", "url": "https://omabrowser.org/oma/group/E1BS52/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A5WWK4-1", "protein_name": "Protein FAM163A", "gene_name": "fam163ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTAGTVVITGGILAAVILLCIIVVLCYCRLQYYCCKKHGSDPDAVCPQPQLSYGVDGMVCAPLSPSPDSNFCPSCSPYSSTFYIHNGGERLIYLPSQYSNTRAMSTDV", "length": 108 }, "evidence": [ { "id": "E1BS52", "url": "https://omabrowser.org/oma/group/E1BS52/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZIK4-1", "protein_name": "Family with sequence similarity 163, member A", "gene_name": "Fam163a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKGTDDEEAEEEEEAEEHDLSLHPRAPTCNACSSQVLDGRGSLAPLTSESCSQPCGVASHCTTCSPYRTPFYIRTADMVPNGGGGERLSFAPTYYKEGGTPSLKLAAPQSYPVTWPSSGHEAFTNPRAISTDV", "length": 168 }, "evidence": [ { "id": "E1BS52", "url": "https://omabrowser.org/oma/group/E1BS52/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CAA5-1", "protein_name": "Protein FAM163A", "gene_name": "Fam163a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKGTDGEDAEEEEEEEEHGLSIHPRVPACNACSSHVLDGRGGLAPLTSESCSQPCGVASHCTTCSPYRTPFYIRTADMVPNGGGGERLSFAPTHYKEGGTPSLKLAAPQNYPVTWPSSGHEAFTNPRAISTDV", "length": 168 }, "evidence": [ { "id": "E1BS52", "url": "https://omabrowser.org/oma/group/E1BS52/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GL9-1", "protein_name": "Protein FAM163A", "gene_name": "FAM163A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSGTEVADEEEEREHDLPTHPRGPTCNACSSQALDGRGSLAPLTSEPCSQPCGVAASHCTTCSPYSSPFYIRTADMVPNGGGGERLSFAPTYYKEGGPPSLKLAAPQSYPVTWPGSGREAFTNPRAISTDV", "length": 167 }, "evidence": [ { "id": "E1BS52", "url": "https://omabrowser.org/oma/group/E1BS52/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BS52", "url": "https://www.uniprot.org/uniprotkb/E1BS52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BS52-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 159, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BS52-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BS52" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSC8-1", "uniprot_ac": "E1BSC8", "uniprot_id": "E1BSC8_CHICK", "mass": { "chemical_mass": 37939.0, "monoisotopic_mass": 37939.0 }, "refseq": { "ac": "XP_015147520", "name": "talin rod domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147520" }, "gene_names": [ { "name": "MESDC1", "type": "recommended", "evidence": [ { "id": "E1BSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC8" } ] }, { "name": "MESDC1", "type": "synonym", "evidence": [ { "id": "XP_015147520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147520" } ] } ], "protein_names": [ { "name": "Talin rod domain containing 1", "type": "synonym", "evidence": [ { "id": "E1BSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC8/entry#names_and_taxonomy" } ] }, { "name": "talin rod domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015147520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147520" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147520" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSC8", "url": "https://www.uniprot.org/uniprotkb/E1BSC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MESDC1", "url": "https://www.uniprot.org/uniprotkb/E1BSC8", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000006399", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006399", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415473", "url": "https://www.ncbi.nlm.nih.gov/gene/415473", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042799", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042799", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415473", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415473", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHCKVKM", "url": "https://omabrowser.org/oma/group/DHCKVKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSC8", "url": "https://www.orthodb.org/?gene=E1BSC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47133:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47133:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21896", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21896", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147520", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BSC8", "url": "https://www.uniprot.org/uniprotkb/E1BSC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSC8-1", "url": "https://www.uniprot.org/uniprotkb/E1BSC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGGSGKSSSEVSGGGIPSGSSLQRKKLISICDHCKIKMQLVADLLLLSSETRPVNTESLSVFGESFEKCRDTIIARTKGLSILTHDVQSQLNMGRFGEVGESLMEMGELVVSLTECSAHAAYLAAVETPGAQPAMPGLVDRYKVTRCRHEVEHGCGVLKTTPLADMSPQLLLEVSQNMSKNLKFLTDACVLASEKSKDKFAKEQFKLSVKCMSTSASALLACVKEVKTSPSELTRNRCVLFSGPLVQSVYALVGFATEPQFLGKAATINPEGKAVQTAILGGAMSVVSACVLLTQCLRDIAQHPESSTKMSDYRERLRNSACAVSDGCNLLSQALRERSSPRTLPPVNSNSVN", "length": 355, "header": "tr|E1BSC8-1|E1BSC8_CHICK Isoform 1 of Talin rod domain containing 1 OS=Gallus gallus OX=9031 GN=MESDC1 PE=4 SV=3 CANONICAL=E1BSC8-1" }, "isoforms": [ { "isoform_ac": "E1BSC8-1", "url": "https://www.uniprot.org/uniprotkb/E1BSC8/entry#E1BSC8-1", "sequence": { "sequence": "MASGGSGKSSSEVSGGGIPSGSSLQRKKLISICDHCKIKMQLVADLLLLSSETRPVNTESLSVFGESFEKCRDTIIARTKGLSILTHDVQSQLNMGRFGEVGESLMEMGELVVSLTECSAHAAYLAAVETPGAQPAMPGLVDRYKVTRCRHEVEHGCGVLKTTPLADMSPQLLLEVSQNMSKNLKFLTDACVLASEKSKDKFAKEQFKLSVKCMSTSASALLACVKEVKTSPSELTRNRCVLFSGPLVQSVYALVGFATEPQFLGKAATINPEGKAVQTAILGGAMSVVSACVLLTQCLRDIAQHPESSTKMSDYRERLRNSACAVSDGCNLLSQALRERSSPRTLPPVNSNSVN", "length": 355, "header": "tr|E1BSC8-1|E1BSC8_CHICK Isoform 1 of Talin rod domain containing 1 OS=Gallus gallus OX=9031 GN=MESDC1 PE=4 SV=3 CANONICAL=E1BSC8-1" }, "locus": { "chromosome": "10", "start_pos": 12237647, "end_pos": 12236583, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046611.1", "url": "https://www.ensembl.org/id/ENSGALT00010046611.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027759.1", "url": "https://www.ensembl.org/id/ENSGALP00010027759.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415473", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415473", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZYJ5-1", "protein_name": "Talin rod domain-containing protein 1", "gene_name": "TLNRD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASGSAGKPTGEAASPAPASVVVGGASSQPRKRLVSVCDHCKGKMQLVADLLLLSSEARPVLFEGPASSCAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKAAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSAEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGGAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "length": 363 }, "evidence": [ { "id": "E1BSC8", "url": "https://omabrowser.org/oma/group/E1BSC8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5BJV3-1", "protein_name": "Talin rod domain-containing protein 1", "gene_name": "Tlnrd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGSAGKPTGEAASPAPGSAVGGASSQPRKRLVSICDHCKGKMQLVADLLLLSSEARPVLFEGPASPGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKAAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSTEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGSAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "length": 362 }, "evidence": [ { "id": "E1BSC8", "url": "https://omabrowser.org/oma/group/E1BSC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERE8-1", "protein_name": "Talin rod domain-containing protein 1", "gene_name": "Tlnrd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGSAGKPTGEAASPAPGSAVGGASSQPRKRLVSICDHCKGKMQLVADLLLLSSEARPVLFEGPASPGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKAAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSTEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGSAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "length": 362 }, "evidence": [ { "id": "E1BSC8", "url": "https://omabrowser.org/oma/group/E1BSC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1K6-1", "protein_name": "Talin rod domain-containing protein 1", "gene_name": "TLNRD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGSAGKPTGEAASPAPASAIGGASSQPRKRLVSVCDHCKGKMQLVADLLLLSSEARPVLFEGPASSGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKVAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSAEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGGAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "length": 362 }, "evidence": [ { "id": "E1BSC8", "url": "https://omabrowser.org/oma/group/E1BSC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1BSC8", "url": "https://www.uniprot.org/uniprotkb/E1BSC8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BSC8", "url": "https://www.uniprot.org/uniprotkb/E1BSC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "E1BSC8", "url": "https://www.uniprot.org/uniprotkb/E1BSC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSC8" }, { "id": "PF21896", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21896" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Talin IBS2B", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 261, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSD0-1", "uniprot_ac": "E1BSD0", "uniprot_id": "E1BSD0_CHICK", "mass": { "chemical_mass": 32588.0, "monoisotopic_mass": 32588.0 }, "refseq": { "ac": "XP_424940", "name": "caspase activity and apoptosis inhibitor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424940" }, "gene_names": [ { "name": "CAAP1", "type": "recommended", "evidence": [ { "id": "E1BSD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSD0" } ] }, { "name": "CAAP1", "type": "synonym", "evidence": [ { "id": "XP_424940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424940" } ] } ], "protein_names": [ { "name": "Caspase activity and apoptosis inhibitor 1", "type": "synonym", "evidence": [ { "id": "E1BSD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSD0/entry#names_and_taxonomy" } ] }, { "name": "caspase activity and apoptosis inhibitor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_424940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424940" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_424940.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424940" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSD0", "url": "https://www.uniprot.org/uniprotkb/E1BSD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAAP1", "url": "https://www.uniprot.org/uniprotkb/E1BSD0", "locus": { "chromosome": "Z", "start_pos": 69060818, "end_pos": 69080972, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006378", "url": "https://www.ensembl.org/id/ENSGALG00010006378" } ] } } ], "crossref": [ { "id": "E1BSD0", "url": "https://alphafold.ebi.ac.uk/entry/E1BSD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001765", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001765", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427364", "url": "https://www.ncbi.nlm.nih.gov/gene/427364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QVPEKKD", "url": "https://omabrowser.org/oma/group/QVPEKKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSD0", "url": "https://www.orthodb.org/?gene=E1BSD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14740:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14740:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424940", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BSD0", "url": "https://www.uniprot.org/uniprotkb/E1BSD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSD0-1", "url": "https://www.uniprot.org/uniprotkb/E1BSD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGRKSSKEKKRRRSRSCCPDGAAGGDRKRRSAESGRAAPEEEKCNVPSGEKVEEPEQFSDVEEGGLDLSVSLKPVSFYIADKKEMLQQCFCVIGEKKLQKMLPDILKSCSMDEIKRLCLEQLEMLSEKKLLKILEGKSGADSDTDEDGDGEDKTGGESVSQQDNSIDSTSSLREDKLEGQESKQGKGEDSDVLSINADAYDSDIEGPCDEEGSPDMQEDTVRSGAGQIDDLQKDIEKSVNEILGLAESSPKESKAASLAVPPLEDVQPSAQQLELLELEMRARAIKALMKAGDVKKQP", "length": 299, "header": "tr|E1BSD0-1|E1BSD0_CHICK Isoform 1 of Caspase activity and apoptosis inhibitor 1 OS=Gallus gallus OX=9031 GN=CAAP1 PE=4 SV=1 CANONICAL=E1BSD0-1" }, "isoforms": [ { "isoform_ac": "E1BSD0-1", "url": "https://www.uniprot.org/uniprotkb/E1BSD0/entry#E1BSD0-1", "sequence": { "sequence": "MPGRKSSKEKKRRRSRSCCPDGAAGGDRKRRSAESGRAAPEEEKCNVPSGEKVEEPEQFSDVEEGGLDLSVSLKPVSFYIADKKEMLQQCFCVIGEKKLQKMLPDILKSCSMDEIKRLCLEQLEMLSEKKLLKILEGKSGADSDTDEDGDGEDKTGGESVSQQDNSIDSTSSLREDKLEGQESKQGKGEDSDVLSINADAYDSDIEGPCDEEGSPDMQEDTVRSGAGQIDDLQKDIEKSVNEILGLAESSPKESKAASLAVPPLEDVQPSAQQLELLELEMRARAIKALMKAGDVKKQP", "length": 299, "header": "tr|E1BSD0-1|E1BSD0_CHICK Isoform 1 of Caspase activity and apoptosis inhibitor 1 OS=Gallus gallus OX=9031 GN=CAAP1 PE=4 SV=1 CANONICAL=E1BSD0-1" }, "locus": { "chromosome": "Z", "start_pos": 69080885, "end_pos": 69064017, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015226.1", "url": "https://www.ensembl.org/id/ENSGALT00010015226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008945.1", "url": "https://www.ensembl.org/id/ENSGALP00010008945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AC58FX91-1", "protein_name": "Caspase activity and apoptosis inhibitor 1 isoform X1", "gene_name": "caap1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQEGKKREKEKKRSHCDRELDDGQMKRRKSGPSMEECRQPLEPPEGPQEPSELEDGGLDLSRSFKPISGYMQERREMLEQCFSVLGENKLQEMLPDGLKDCSLNEIKKLCWDQLLQISDIHLLEILDGKELSVLAAPEQKSCTDSQQDSNVDSTSSLRDNPDTEEKQGKINTYQRSTPQFPARFVCLCFCVCAFVCFIYLCVLFVCVVCVSVFVCFIYLCVLFICACVCVCVFVCAFVCLSICVCMCVCLCVFVCAFVCVMFVCVYVCVCVSVCAFVCFIYLCVCVCLFLCVLLCFVCVCVCFCVCFLFLSICVCACVYVCVCVFVCACVFYLCVCVCVLLCVLFVCVCVCVCVCVCVCVLLCVLCVCVCVCVCVLCVLFVFLSICVLFVCVRVCLCFCVCLCVLFVCVCVCAFVCFVCVCVCVCVCVCVCFVCAFCFICVCACVSVCIFVCVCVWGGVVNVCICFFHLHVCV", "length": 473 }, "evidence": [ { "id": "E1BSD0", "url": "https://omabrowser.org/oma/group/E1BSD0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SP80-1", "protein_name": "Caspase activity and apoptosis inhibitor 1", "gene_name": "CAAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGKKSSREKRRKRSGQEAAAALAAPELVPAVAGSGSGSTSGCGSASGCGSVTCCGNTSFSGSVTGTGSGGSCWGGSGVERSERRKRRSTDSSSSVSGSLQQEAKYLLPTLDKELFLAEHSDLEEGGLDLTVALKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQEQLELLSEKKILKILEGDNAVDSDMEEEADDGSKMGSELVSQQDICTDSTSSLKENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEVPENTVQSEAGQIDDLEKDIEKSVNEILGLAESSPKEPKAATLTVPPPEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPA", "length": 362 }, "evidence": [ { "id": "E1BSD0", "url": "https://omabrowser.org/oma/group/E1BSD0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V6Y7-1", "protein_name": "Caspase activity and apoptosis inhibitor 1", "gene_name": "Caap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGKKSSREKRRKRSGQEAAAALAAPDLVPVLSGSAGGCGSVGCCGVAGGGTSVAGGAERSERRKRRSTDSSSSVSGSLQQETKYLLPSLEKELILAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEQKLQKMLPDVLKNCSVEEIKKLCQEQLELLSEKKILKILEGDNGLDSDMEEEADRGSKVAPDLISQQDTCVDSTSSLRENKQPEGLESKQGKGEDSDVLSINADAYDSDIEGPSNEEAAASATAAPTATAVATAASASEVPGGTVQSEAAQIDDLERDIEKSVNEILGLVESSPKEPKAAILTVPPPEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPV", "length": 358 }, "evidence": [ { "id": "E1BSD0", "url": "https://omabrowser.org/oma/group/E1BSD0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2T9W9-1", "protein_name": "Caspase activity and apoptosis inhibitor 1", "gene_name": "CAAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGKKSSREKRRKRSGQEAAAALAAPDLVPAVGGSGSGSTSGCGSASGCGSVTCCGNTSVSGSVTGGGSGGSCWGGSSVERGERRKRRSTDSSSSVSGSLQQEAKYLLPPLEKELFLAEHSDLEEGGLDLTVALKPVSFYISDKKEMLRQCFCIIGEKKLQKMLPDVLKNCSIEEIKRLCQEQLELLSEKKILKILEGDNGMDSEMEEEADDGSKMVSDVVNQQDSCVDSTSSLRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEVPENTVQSEAGQIDDLEKDIEKSVNEILGLAESSPKEPKAATLTVPPPEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPA", "length": 362 }, "evidence": [ { "id": "E1BSD0", "url": "https://omabrowser.org/oma/group/E1BSD0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VDY9-1", "protein_name": "Caspase activity and apoptosis inhibitor 1", "gene_name": "Caap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGKKSSREKRRKRSGQEAAASLAAPDLVPVLSGSAGGCGSGGCCGVAGGGTSVAGGAERSERRKRRSTDSSSSVSGSLQQETKYLLPSLEKELFLAEHSDLEEGGLDLNVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSVEEIKKLCQEQLELLSEKQILKILEGDNGLDSDMEEEADDGCKVAPDLISQQDTCVDSTSSLRENKQPEVLESKQGKGEDSDVLSINADAYDSDIEGPSIDEAAAAATATPAATAVATAASEVPENTVQSEAGQIDDLERDIEKSVNEILGLAESSPKEPKVATLTVPPAEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPV", "length": 356 }, "evidence": [ { "id": "E1BSD0", "url": "https://omabrowser.org/oma/group/E1BSD0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8G2-1", "protein_name": "Caspase activity and apoptosis inhibitor 1", "gene_name": "CAAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRSTDSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQEQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGKGEDSDVLSINADAYDSDIEGPCNEEAAAPEAPENTVQSEAGQIDDLEKDIEKSVNEILGLAESSPNEPKAATLAVPPPEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPA", "length": 361 }, "evidence": [ { "id": "E1BSD0", "url": "https://omabrowser.org/oma/group/E1BSD0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "E1BSD0", "url": "https://www.uniprot.org/uniprotkb/E1BSD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSD0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 299, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSD0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSD0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSD3-1", "uniprot_ac": "E1BSD3", "uniprot_id": "E1BSD3_CHICK", "mass": { "chemical_mass": 38678.0, "monoisotopic_mass": 38678.0 }, "refseq": { "ac": "XP_015130976", "name": "aspartate beta-hydroxylase domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130976" }, "gene_names": [ { "name": "ASPHD1", "type": "recommended", "evidence": [ { "id": "E1BSD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSD3" } ] }, { "name": "ASPHD1", "type": "synonym", "evidence": [ { "id": "XP_015130976", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130976" } ] } ], "protein_names": [ { "name": "Aspartate beta-hydroxylase domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "E1BSD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSD3/entry#names_and_taxonomy" } ] }, { "name": "aspartate beta-hydroxylase domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_015130976", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130976" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130976" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSD3", "url": "https://www.uniprot.org/uniprotkb/E1BSD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASPHD1", "url": "https://www.uniprot.org/uniprotkb/E1BSD3", "locus": {} } ], "crossref": [ { "id": "E1BSD3", "url": "https://alphafold.ebi.ac.uk/entry/E1BSD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023396", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023396", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "425447", "url": "https://www.ncbi.nlm.nih.gov/gene/425447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007803", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007803", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425447", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIPSKDC", "url": "https://omabrowser.org/oma/group/HIPSKDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSD3", "url": "https://www.orthodb.org/?gene=E1BSD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46332:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46332:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015130976", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130976", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BSD3", "url": "https://www.uniprot.org/uniprotkb/E1BSD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSD3-1", "url": "https://www.uniprot.org/uniprotkb/E1BSD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLVWLPDWSCSLDGLRDFIAAGIQSFRDCDGGALLAVGCLLLLFVWYCYHVGREQPRAYPAVNALMQGAEANGVQNGFVYCHAPECARCSPHDGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTAPYFSRDAQKHDVEVLERNFQTILCEFESLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGMCVPRNCRRCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVIAEHYGPTNIRIRCHLGLKTPSNCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGPPEEGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "length": 343, "header": "tr|E1BSD3-1|E1BSD3_CHICK Isoform 1 of Aspartate beta-hydroxylase domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ASPHD1 PE=3 SV=3 CANONICAL=E1BSD3-1" }, "isoforms": [ { "isoform_ac": "E1BSD3-1", "url": "https://www.uniprot.org/uniprotkb/E1BSD3/entry#E1BSD3-1", "sequence": { "sequence": "MPLVWLPDWSCSLDGLRDFIAAGIQSFRDCDGGALLAVGCLLLLFVWYCYHVGREQPRAYPAVNALMQGAEANGVQNGFVYCHAPECARCSPHDGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTAPYFSRDAQKHDVEVLERNFQTILCEFESLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGMCVPRNCRRCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVIAEHYGPTNIRIRCHLGLKTPSNCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGPPEEGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "length": 343, "header": "tr|E1BSD3-1|E1BSD3_CHICK Isoform 1 of Aspartate beta-hydroxylase domain-containing protein 2 OS=Gallus gallus OX=9031 GN=ASPHD1 PE=3 SV=3 CANONICAL=E1BSD3-1" }, "locus": { "chromosome": "15", "start_pos": 7150900, "end_pos": 7147913, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057254.1", "url": "https://www.ensembl.org/id/ENSGALT00010057254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034817.1", "url": "https://www.ensembl.org/id/ENSGALP00010034817.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425447", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BAL9-1", "protein_name": "Aspartate beta-hydroxylase domain-containing protein 2", "gene_name": "ASPHD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSLEWLVAWGWSLDGLRDCIAAGIQSVRDCDTTAAVSVACLLALFVWYCYHVGREQPRAYASVNALMQGPDAAGLQNGFVYCQSAECVRCSHSEGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLSSRPSIQKPEVFFLPDLPTAPYFSREAQKHDVELLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWVTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACLSVLSPGTVITEHYGPTNIRVRCHLGLKTPSGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGPAEDGPRAVFMVDLWHPHVAAAERQALDFIFAPGR", "length": 343 }, "evidence": [ { "id": "E1BSD3", "url": "https://omabrowser.org/oma/group/E1BSD3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RG81-1", "protein_name": "Aspartate beta-hydroxylase domain-containing protein 2", "gene_name": "ASPHD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLEWLVAWGWSLDGLRDCIATGIQSVRDCDTTAVVTVACLLVLFVWYCYHVGREQPRPYVSVNALMQGPDANGLQNGFVYCQSPECVRCSHNGGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTTPYFSRDAQKHDVELLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWVTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPGGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "length": 343 }, "evidence": [ { "id": "E1BSD3", "url": "https://omabrowser.org/oma/group/E1BSD3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HTB6-1", "protein_name": "Aspartate beta-hydroxylase domain-containing protein 2", "gene_name": "Asphd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWLEWLVAWSWSLDGLRDCIATGIQSVRDCDSTAVVTVACLLVMFVWYCYHVGREQPRPHVSVNSLLQGVDASVLQNGSMYCQSPECVRCMHHDGLNQKLYHNLQEYAKRYSWSGMGRIHKAIREQGRYLSSQPSIQKPEVFFLPDLPTTPYFSRDAQKHDVELLERNFQAILCEFETLYKAFSNCSLPQGWKVNSTPSGEWFTFDFVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPSGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "length": 343 }, "evidence": [ { "id": "E1BSD3", "url": "https://omabrowser.org/oma/group/E1BSD3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5HZW3-1", "protein_name": "Aspartate beta-hydroxylase domain-containing protein 2", "gene_name": "Asphd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLEWLVAWSWSLDGLRDCIATGIQSVRDCDGTAVITVACLLVLFVWYCYHVGREQPRPHVSVNSLLQGVDANGLQNGSMYCQSPECVRCTHHDGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLSSQPSIQKPEVFFLPDLPTTPYFPRDAQKHDVELLERNFQAILCEFEALYKAFSNCSLPQGWKVNSTPSGEWFTFDFVSQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLFDDSFLHTSFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "length": 343 }, "evidence": [ { "id": "E1BSD3", "url": "https://omabrowser.org/oma/group/E1BSD3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ICH7-1", "protein_name": "Aspartate beta-hydroxylase domain-containing protein 2", "gene_name": "ASPHD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVWAPLGPPRTDCLTLLHTPSKDSPKMSLEWLVAWSWSLDGLRDCIATGIQSVRDCDTTAVITVACLLVLFVWYCYHVGREQPRPYVSVNSLMQAADANGLQNGYVYCQSPECVRCTHNEGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNSRPSIQKPEVFFLPDLPTTPYFSRDAQKHDVEVLERNFQTILCEFETLYKAFSNCSLPQGWKMNSTPSGEWFTFYLVNQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLFDDSFLHAAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "length": 369 }, "evidence": [ { "id": "E1BSD3", "url": "https://omabrowser.org/oma/group/E1BSD3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80VP9-1", "protein_name": "Aspartate beta-hydroxylase domain-containing protein 2", "gene_name": "Asphd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLEWLVAWSWSLDGLRDCIATGIQSVRDCDGTAVITVACLLILFVWYCYHVGREQPRPHVSVNSLLQGVDANGLQNGSMYCQSPECARCTHHEGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLSSQPSIQKPEVFFLPDLPTTPYFSRDAQKHDVELLERNFQAILCEFETLYKAFSNCSLPQGWKVNSTPSGEWFTFDFVSQGVCVPRNCRKCPRTYRLLGSLRTCIGNNVFGNACISVLSPGTVITEHYGPTNIRIRCHLGLKTPNGCELVVGGEPQCWAEGRCLLFDDSFLHTAFHEGSAEDGPRVVFMVDLWHPNVAAAERQALDFIFAPGR", "length": 343 }, "evidence": [ { "id": "E1BSD3", "url": "https://omabrowser.org/oma/group/E1BSD3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BSD3", "url": "https://www.uniprot.org/uniprotkb/E1BSD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "E1BSD3", "url": "https://www.uniprot.org/uniprotkb/E1BSD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSD3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 343, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSD3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSD3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BSD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSD3" }, { "id": "PF05118", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aspartyl/asparaginy/proline hydroxylase", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 325, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 195, "end_pos": 197 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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gene 1-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430446" }, "gene_names": [ { "name": "GSG1L", "type": "recommended", "evidence": [ { "id": "E1BSG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ] }, { "name": "GSG1L", "type": "synonym", "evidence": [ { "id": "XP_430446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430446" } ] } ], "protein_names": [ { "name": "Germ cell-specific gene 1-like protein", "type": "recommended", "evidence": [ { "id": "E1BSG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSG3/entry#names_and_taxonomy" } ] }, { "name": "germ cell-specific gene 1-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_430446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430446" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_430446.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_430446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430446" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GSG1L", "url": "https://www.uniprot.org/uniprotkb/E1BSG3", "locus": { "chromosome": "14", "start_pos": 11895022, "end_pos": 11832049, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019015", "url": "https://www.ensembl.org/id/ENSGALG00010019015" } ] } } ], "crossref": [ { "id": "E1BSG3", "url": "https://alphafold.ebi.ac.uk/entry/E1BSG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000036373", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000036373", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426763", "url": "https://www.ncbi.nlm.nih.gov/gene/426763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HEPITYF", "url": "https://omabrowser.org/oma/group/HEPITYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NTY4", "url": "https://www.orthodb.org/?gene=A0A1D5NTY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8D4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9V1", "url": "https://www.orthodb.org/?gene=A0A8V0Z9V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFV9", "url": "https://www.orthodb.org/?gene=A0A8V0ZFV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSG3", "url": "https://www.orthodb.org/?gene=E1BSG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07803", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07803", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_430446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430446", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NTY4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NTY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NTY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8D4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9V1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSG3-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTNRRCRALLAVSLNLMALLFSTTAFITTHWCEGTQRVPKPSCGKEKKTNCLNYSGNETANETNQNVVHYSWETGDDRFLFRYFHTGIWYSCEENINAAGERCRSFIDLAPASEKGVLWLSVVSEVLYIMLLVVGFSLMCLELFHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKIFEQGFREEQNFLDQEAIKYFRERASQHPALNVTSTQRNRSDHNAQKISPFATSSSSSNISSSSSLSSEPTCQISMVQDQAQLDIVSISRLAPGESPSPQPFERRSKSLAISCSSQLGTRTPPASCPASPRLSLTPSSAKPQQYSDSSPASPGTNAASFYALCPQTAHSLEASASDYTLTPTRKSTRPPTTPEDSSQSPGSSKTGLRTIGKGFQSHLENPDHERRFVTTEEFQAMEKELEDVKDELKCLKWKVRHIGETVQPLAEDSKRYNGYTLTELKAMVQSEEDPYKAAHKILTALFSDVYLLQHSVTEQTSNARSLPRPKIDPELYTVYCDILKSIFPGISSQTLREQTQHMQKST", "length": 597, "header": "tr|E1BSG3-1|E1BSG3_CHICK Isoform 1 of Germ cell-specific gene 1-like protein OS=Gallus gallus OX=9031 GN=GSG1L PE=3 SV=5 CANONICAL=E1BSG3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NTY4-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG3/entry#A0A1D5NTY4-1", "sequence": { "sequence": "MKTNRRCRALLAVSLNLMALLFSTTAFITTHWCEGTQRVPKPSCGKEKKTNCLNYSGNETANETNQNVVHYSWETGDDRFLFRYFHTGIWYSCEENINAAGERCRSFIDLAPASEKGVLWLSVVSEVLYIMLLVVGFSLMCLELFHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKIFEQGFREEQNFLDQEAIKYFRERTEEERAEAGDLRLQCLHSCSPNRLHNTQL", "length": 290, "header": "tr|A0A1D5NTY4-1|A0A1D5NTY4_CHICK Computationally mapped isoform of Germ cell-specific gene 1-like protein OS=Gallus gallus OX=9031 GN=GSG1L PE=3 SV=2 CANONICAL=E1BSG3-1" }, "locus": { "chromosome": "14", "start_pos": 11888156, "end_pos": 11832582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046038.1", "url": "https://www.ensembl.org/id/ENSGALT00010046038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027435.1", "url": "https://www.ensembl.org/id/ENSGALP00010027435.1" } ] } }, { "isoform_ac": "A0A8V0Z8D4-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG3/entry#A0A8V0Z8D4-1", "sequence": { "sequence": "MKTNRRCRALLAVSLNLMALLFSTTAFITTHWCEGTQRVPKPSCGKEKKTNCLNYSGNETANETNQNVVHYSWETGDDRFLFRYFHTGIWYSCEENINAAGERCRSFIDLAPASEKGVLWLSVVSEVLYIMLLVVGFSLMCLELFHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFWASQHPALNVTSTQRNRSDHNAQKISPFATSSSSSNISSSSSLSSEPTCQISMVQDQAQLDIVSISRLAPGESPSPQPFERRSKSLAISCSSQLGTRTPPASCPASPRLSLTPSSAKPQQYSDSSPASPGTNAASFYALCPQTAHSLEASASDYTLTPTRKSTRPPTTPEDSSQSPGSSKTGLRTIGKGFQSHLENPDHERRFVTTEEFQAMEKELEDVKDELKCLKWKVRHIGETVQPLAEDSKRYNGYTLTELKAMVQSEEDPYKAAHKILTALFSDVYLLQHSVTEQTSNARSLPRPKIDPELYTVYCDILKSIFPGISSQTLREQTQHMQKST", "length": 541, "header": "tr|A0A8V0Z8D4-1|A0A8V0Z8D4_CHICK Computationally mapped isoform of Germ cell-specific gene 1-like protein OS=Gallus gallus OX=9031 GN=GSG1L PE=3 SV=1 CANONICAL=E1BSG3-1" }, "locus": { "chromosome": "14", "start_pos": 11889951, "end_pos": 11832582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046025.1", "url": "https://www.ensembl.org/id/ENSGALT00010046025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027422.1", "url": "https://www.ensembl.org/id/ENSGALP00010027422.1" } ] } }, { "isoform_ac": "A0A8V0Z9V1-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG3/entry#A0A8V0Z9V1-1", "sequence": { "sequence": "MKTNRRCRALLAVSLNLMALLFSTTAFITTHWCEGTQRVPKPSCGKEKKTNCLNYSGNETANETNQNVVHYSWETGDDRFLFRYFHTGIWYSCEENINAAGVLWLSVVSEVLYIMLLVVGFSLMCLELFHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFWASQHPALNVTSTQRNRSDHNAQKISPFATSSSSSNISSSSSLSSEPTCQISMVQDQAQLDIVSISRLAPGESPSPQPFERRSKSLAISCSSQLGTRTPPASCPASPRLSLTPSSAKPQQYSDSSPASPGTNAASFYALCPQTAHSLEASASDYTLTPTRKSTRPPTTPEDSSQSPGSSKTGLRTIGKGFQSHLENPDHERRFVTTEEFQAMEKELEDVKDELKCLKWKVRHIGETVQPLAEDSKRYNGYTLTELKAMVQSEEDPYKAAHKILTALFSDVYLLQHSVTEQTSNARSLPRPKIDPELYTVYCDILKSIFPGISSQTLREQTQHMQKST", "length": 525, "header": "tr|A0A8V0Z9V1-1|A0A8V0Z9V1_CHICK Computationally mapped isoform of GSG1 like OS=Gallus gallus OX=9031 GN=GSG1L PE=3 SV=1 CANONICAL=E1BSG3-1" }, "locus": { "chromosome": "14", "start_pos": 11889951, "end_pos": 11832582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046021.1", "url": "https://www.ensembl.org/id/ENSGALT00010046021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027418.1", "url": "https://www.ensembl.org/id/ENSGALP00010027418.1" } ] } }, { "isoform_ac": "A0A8V0ZFV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG3/entry#A0A8V0ZFV9-1", "sequence": { "sequence": "MKTNRRCRALLAVSLNLMALLFSTTAFITTHWCEGTQRVPKPSCGKEKKTNCLNYSGNETANETNQNVVHYSWETGDDRFLFRYFHTGIWYSCEENINAAGERCRSFIDLAPASEKGVLWLSVVSEVLYIMLLVVGFSLMCLELFHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKIFEQGFREEQNFLDQEAIKYFRERASQHPALNVTSTQRNRSDHNAQKISPFATSSSSSNISSSSSLSSEPTCQISMVQDQAQLDIVSISRLAPGESPSPQPFERRSKSLAISCSSQLGTRTPPASCPASPRLSLTPSSAKPQQYSDSSPASPGTNAASFYALCPQTAHSLEASASDYTLTPTRKSTRPPTTPEDSSQSPGSSKTGLRTIGKGFQSHLENPDHERGIYFTEMNPTPTGV", "length": 475, "header": "tr|A0A8V0ZFV9-1|A0A8V0ZFV9_CHICK Computationally mapped isoform of Germ cell-specific gene 1-like protein OS=Gallus gallus OX=9031 GN=GSG1L PE=3 SV=1 CANONICAL=E1BSG3-1" }, "locus": { "chromosome": "14", "start_pos": 11894813, "end_pos": 11832582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046045.1", "url": "https://www.ensembl.org/id/ENSGALT00010046045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027442.1", "url": "https://www.ensembl.org/id/ENSGALP00010027442.1" } ] } }, { "isoform_ac": "E1BSG3-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG3/entry#E1BSG3-1", "sequence": { "sequence": "MKTNRRCRALLAVSLNLMALLFSTTAFITTHWCEGTQRVPKPSCGKEKKTNCLNYSGNETANETNQNVVHYSWETGDDRFLFRYFHTGIWYSCEENINAAGERCRSFIDLAPASEKGVLWLSVVSEVLYIMLLVVGFSLMCLELFHSSSVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKIFEQGFREEQNFLDQEAIKYFRERASQHPALNVTSTQRNRSDHNAQKISPFATSSSSSNISSSSSLSSEPTCQISMVQDQAQLDIVSISRLAPGESPSPQPFERRSKSLAISCSSQLGTRTPPASCPASPRLSLTPSSAKPQQYSDSSPASPGTNAASFYALCPQTAHSLEASASDYTLTPTRKSTRPPTTPEDSSQSPGSSKTGLRTIGKGFQSHLENPDHERRFVTTEEFQAMEKELEDVKDELKCLKWKVRHIGETVQPLAEDSKRYNGYTLTELKAMVQSEEDPYKAAHKILTALFSDVYLLQHSVTEQTSNARSLPRPKIDPELYTVYCDILKSIFPGISSQTLREQTQHMQKST", "length": 597, "header": "tr|E1BSG3-1|E1BSG3_CHICK Isoform 1 of Germ cell-specific gene 1-like protein OS=Gallus gallus OX=9031 GN=GSG1L PE=3 SV=5 CANONICAL=E1BSG3-1" }, "locus": { "chromosome": "14", "start_pos": 11889951, "end_pos": 11832582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046030.1", "url": "https://www.ensembl.org/id/ENSGALT00010046030.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027427.1", "url": "https://www.ensembl.org/id/ENSGALP00010027427.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" }, { "name": "asymmetric synapse", "id": "GO:0032279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032279", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of signaling", "id": "GO:0023051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023051", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" }, { "name": "regulation of transport", "id": "GO:0051049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051049", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" }, { "name": "regulation of cell communication", "id": "GO:0010646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010646", "evidence": [ { "database": "UniProtKB", "id": "E1BSG3", "url": "https://www.uniprot.org/uniprotkb/E1BSG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSG3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 597, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSG3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSG3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSG7-1", "uniprot_ac": "E1BSG7", "uniprot_id": "E1BSG7_CHICK", "mass": { "chemical_mass": 70762.0, "monoisotopic_mass": 70762.0 }, "refseq": { "ac": "XP_004937725", "name": "WW domain-binding protein 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937725" }, "gene_names": [ { "name": "WBP11", "type": "recommended", "evidence": [ { "id": "E1BSG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSG7" } ] }, { "name": "WBP11", "type": "synonym", "evidence": [ { "id": "XP_004937725", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937725" } ] } ], "protein_names": [ { "name": "WW domain binding protein 11", "type": "synonym", "evidence": [ { "id": "E1BSG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSG7/entry#names_and_taxonomy" } ] }, { "name": "WW domain-binding protein 11", "type": "synonym", "evidence": [ { "id": "XP_004937725", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937725" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937725" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSG7", "url": "https://www.uniprot.org/uniprotkb/E1BSG7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WBP11", "url": "https://www.uniprot.org/uniprotkb/E1BSG7", "locus": {} } ], "crossref": [ { "id": "E1BSG7", "url": "https://alphafold.ebi.ac.uk/entry/E1BSG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011745", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011745", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427880", "url": "https://www.ncbi.nlm.nih.gov/gene/427880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427880", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427880", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FGMRMPP", "url": "https://omabrowser.org/oma/group/FGMRMPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGH3", "url": "https://www.orthodb.org/?gene=A0A8V0YGH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL89", "url": "https://www.orthodb.org/?gene=A0A8V0YL89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSG7", "url": "https://www.orthodb.org/?gene=E1BSG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13361", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13361", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13361:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13361:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004937725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937725", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSG7", "url": "https://www.uniprot.org/uniprotkb/E1BSG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPVRSISMLPPPGLGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALEMAPRRREEDVSYGSEPGQRGHDDDMSSTSEDEGYPEDMDQDKHDESSDDSDSDRSDADSEGEEFPRRDNDKEREGGEEKKSGHSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEYSEEEEEEEEDSESEDASQQQQQQQQHSEEALAETGSSAAASTQQQQSSQAVASSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGLPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMLRPPLVPPLGPAPPGLYPPAPLPNPGVLSAPPSLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGALAASQRKQDDEPALPLTKAAPKAGSSAPISVQTKDDVYEAFMKEMEGLL", "length": 648, "header": "tr|E1BSG7-1|E1BSG7_CHICK Isoform 1 of WW domain binding protein 11 OS=Gallus gallus OX=9031 GN=WBP11 PE=1 SV=3 CANONICAL=E1BSG7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGH3-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG7/entry#A0A8V0YGH3-1", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPVRSISMLPPPGLGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALEMAPRRREEDVSYGSEPGQRGHDDDMSSTSEEFPRRDNDKEREGGEEKKSGHSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEYSEEEEEEEEDSESEDASQQQQQQQQHSEEALAETGSSAAASTQQQQSSQAVASSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGLPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMLRPPLVPPLGPAPPGLYPPAPLPNPGVLSAPPSLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGALAASQRKQDDEPALPLTKAAPKAGSSAPISVQTKDDVYEAFMKEMEGLL", "length": 616, "header": "tr|A0A8V0YGH3-1|A0A8V0YGH3_CHICK Computationally mapped isoform of WW domain binding protein 11 OS=Gallus gallus OX=9031 GN=WBP11 PE=1 SV=1 CANONICAL=E1BSG7-1" }, "locus": { "chromosome": "1", "start_pos": 48106444, "end_pos": 48098681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029086.1", "url": "https://www.ensembl.org/id/ENSGALT00010029086.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016845.1", "url": "https://www.ensembl.org/id/ENSGALP00010016845.1" } ] } }, { "isoform_ac": "A0A8V0YL89-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG7/entry#A0A8V0YL89-1", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPVRSISMLPPPGLGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALEMAPRRREEDVSYGSEPGQRGHDDDMSSTSEDEGYPEDMDQDKHDESSDDSDSDRSDADSEGEEFPRRDNDKEREGGEEKKSGHSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEYSEEEEEEEEDSESEDASQQQQQQQQHSEEALAETGSSAAASTQQQQSSQAVASSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGLPGLRGPLPRLLPPGPPPGRPPGPPPRGPPPRLPPPAPPGIPPPRPGMLRPPLVPPLGPAPPGLYPPAPLPNPGVLSAPPSLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGALAASQRKQDDEPALPLTKAAPKAGSSAPISVQTKDDVYEAFMKEMEGLL", "length": 636, "header": "tr|A0A8V0YL89-1|A0A8V0YL89_CHICK Computationally mapped isoform of WW domain binding protein 11 OS=Gallus gallus OX=9031 GN=WBP11 PE=1 SV=1 CANONICAL=E1BSG7-1" }, "locus": { "chromosome": "1", "start_pos": 48106444, "end_pos": 48098681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029084.1", "url": "https://www.ensembl.org/id/ENSGALT00010029084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016843.1", "url": "https://www.ensembl.org/id/ENSGALP00010016843.1" } ] } }, { "isoform_ac": "E1BSG7-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG7/entry#E1BSG7-1", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPVRSISMLPPPGLGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALEMAPRRREEDVSYGSEPGQRGHDDDMSSTSEDEGYPEDMDQDKHDESSDDSDSDRSDADSEGEEFPRRDNDKEREGGEEKKSGHSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEYSEEEEEEEEDSESEDASQQQQQQQQHSEEALAETGSSAAASTQQQQSSQAVASSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGLPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMLRPPLVPPLGPAPPGLYPPAPLPNPGVLSAPPSLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGALAASQRKQDDEPALPLTKAAPKAGSSAPISVQTKDDVYEAFMKEMEGLL", "length": 648, "header": "tr|E1BSG7-1|E1BSG7_CHICK Isoform 1 of WW domain binding protein 11 OS=Gallus gallus OX=9031 GN=WBP11 PE=1 SV=3 CANONICAL=E1BSG7-1" }, "locus": { "chromosome": "1", "start_pos": 48106444, "end_pos": 48098681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029083.1", "url": "https://www.ensembl.org/id/ENSGALT00010029083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016841.1", "url": "https://www.ensembl.org/id/ENSGALP00010016841.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427880", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427880", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QEI2-1", "protein_name": "Wbp11/ELF5/Saf1 N-terminal domain-containing protein", "gene_name": "WBP11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDRSDGESEGDEFVHRDDTERENNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEDSLSDGTSAASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATATPQRKSEDDSAVPLAKAAPKSGPAVPVSVQTKDDVYEAFMKEMEGLL", "length": 641 }, "evidence": [ { "id": "E1BSG7", "url": "https://omabrowser.org/oma/group/E1BSG7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BNM6-1", "protein_name": "WW domain binding protein 11", "gene_name": "WBP11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPTRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDSDRSDGESEGDEFVHRDDTERENNEEKKSGLSVRFADMPGKSRKKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEEDDEDSDDSEAEKQSQKQHKEESLSDGTSAASQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGAAAAPQRKSEDDSAVPLAKTAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL", "length": 640 }, "evidence": [ { "id": "E1BSG7", "url": "https://omabrowser.org/oma/group/E1BSG7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O76861-1", "protein_name": "Wbp11/ELF5/Saf1 N-terminal domain-containing protein", "gene_name": "EG:100G10.1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGRRSINTTKSGKYMNPTDQARKEARKKELKKNKKQRQMVRAAVLKNKDPSQILEEMEKIDEMEYNVLQPSPLNEKVLRDKRKKLKETFDRVMRLYHNDEPEHWADLKRKEVEYEKKRLKKQQYYESVKHAQSVQIDEIPLPAPVSAVSGGSTETTGGSVVAGFGASVVIRLPPPPMTMALPPYAPGAPPGVSRNSDLASEAQVEKSKENEQKDWLGVPPGPPPDLFAFSELNSDAEGNTDYDGEGEEEEPEPLKKGKDKEKDKNSEATEPNNQNIDDFMKEMEHVHKRKHRKLAAKEDEADKKREEDDGKDIDKIEERTSDSDKRTASSTDDEDDDDQDEDENMPEVPTKPASVKSSTATPAPAPPTAPTLPTIPLPPASSVPAPPQLPHLPPIPNLGPPGIMYRPPPMRPPHPGSGFGIRMPPGPPPGPRAPHGLGPIPRMGIRMPPGPPPGLPPRLAHHNKQGGGAGAPKESAKGVATITAKPQIRNLSADVTRFVPSTLRVKREDQRRTARPRHAANDGHHAHSEAHSKPPTKDDAYLQFMNEMQGLL", "length": 552 }, "evidence": [ { "id": "E1BSG7", "url": "https://omabrowser.org/oma/group/E1BSG7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5PQQ2-1", "protein_name": "WW domain-binding protein 11", "gene_name": "Wbp11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDMSSTSEDDGYPEDMDQDKHDDSTEDSDTDRSDAESDGDEFGHRDDSERDNTEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEEEDDDDSEDSEAEKPSQKQHKEDSHADGSSAASSQQQAPPQAVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGIRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPSLIQRPKADDASAATIEKKATATISAKPQITNPKAEVTRFVPTALRVRRENKGATAVPQRRSEEDSAVPVAKAAPRSGPSVPVSVQTKDDVYEAFMKEMEGLL", "length": 641 }, "evidence": [ { "id": "E1BSG7", "url": "https://omabrowser.org/oma/group/E1BSG7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q923D5-1", "protein_name": "WW domain-binding protein 11", "gene_name": "Wbp11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPARAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDMSSTSEDDGYPEDMDQDKHDDSTEDSDTDRSDAESDGDEFGHREDSERDNTEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEEEDADDSDDSEAEKQSQKQHKDDGHSDSTAAASSQQQAPPQSAPASQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGIRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPSLIQRPKADDASAATIEKKATATISAKPQITNPKAEVTRFVPTALRVRRENKGATAVPQRRSEDDSAVPVAKAAPRSGPSVAVSVQTKDDVYEAFMKEMEGLL", "length": 641 }, "evidence": [ { "id": "E1BSG7", "url": "https://omabrowser.org/oma/group/E1BSG7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LV14-1", "protein_name": "Protein EARLY FLOWERING 5", "gene_name": "ELF5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKTTKGGKVMNPTDAYRKQIRKREIKRNKKERQKVREVGILKKDPEQIKDQIRKLDMSKAEGALDKARKHKKRQLEDTLKMVVKKRKEYDEKKKEQGEATTSVMFSHLPPQRRLTGEEDLKPEDSVYYHPTLNPTGAPPPGKPPMYNSSIGLAISSDGASSSSAALSSITESEDSVLVNPPPLPPLPDGDNALSASLPLPPLPPLPPTTGLTLPHSPFPPPPPGPPPKEQDFVRPPLPPPPQLPQSSQPPPPGLSGSQGDGRFPESSDFTFDNRMNANITSVPLLPPPGIPSNESESRPAESNASSFQNANLSKMVAPPPPAPLHQQHQSTFAGAAASLTNFQPDVHPPPGMLRFPPPPPPLDMHPPHPGMFVGHLIPRPPYGPPPGPPPMMRPPLPPGPPPSSFQDGQAMIRPYVPNKPSFVKSAAPTVVRRPLAQHTPELTSMVPASVRVRRESATVTKPKPKTSIASSLSFTPRAMASAATVKVEPAKTSAASKPQSIDDSYTAFLEDMKALGALDG", "length": 520 }, "evidence": [ { "id": "E1BSG7", "url": "https://omabrowser.org/oma/group/E1BSG7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y2W2-1", "protein_name": "WW domain-binding protein 11", "gene_name": "WBP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPVSVQTKDDVYEAFMKEMEGLL", "length": 641 }, "evidence": [ { "id": "E1BSG7", "url": "https://omabrowser.org/oma/group/E1BSG7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BSG7", "url": "https://www.uniprot.org/uniprotkb/E1BSG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "E1BSG7", "url": "https://www.uniprot.org/uniprotkb/E1BSG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "E1BSG7", "url": "https://www.uniprot.org/uniprotkb/E1BSG7" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "E1BSG7", "url": "https://www.uniprot.org/uniprotkb/E1BSG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSG7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 648, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSG7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSG7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BSG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSG7" }, { "id": "PF09429", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09429" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Wbp11/ELF5/Saf1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 92, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSG9-1", "uniprot_ac": "E1BSG9", "uniprot_id": "E1BSG9_CHICK", "mass": { "chemical_mass": 8946.0, "monoisotopic_mass": 8946.0 }, "refseq": { "ac": "NP_001182367", "name": "protein FAM240A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" }, "gene_names": [ { "name": "LOC427470", "type": "recommended", "evidence": [ { "id": "E1BSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSG9" } ] }, { "name": "FAM240A", "type": "synonym", "evidence": [ { "id": "NP_001182367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" } ] }, { "name": "FAM240B", "type": "synonym", "evidence": [ { "id": "NP_001182367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" } ] }, { "name": "LOC427470", "type": "synonym", "evidence": [ { "id": "NP_001182367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "E1BSG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSG9/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 240 member A", "type": "synonym", "evidence": [ { "id": "NP_001182367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" } ] }, { "name": "family with sequence similarity 240 member B", "type": "synonym", "evidence": [ { "id": "NP_001182367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" } ] }, { "name": "protein FAM240A", "type": "synonym", "evidence": [ { "id": "NP_001182367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CV858138.1, BU450036.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02738220 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000094.1. On Sep 11, 2010 this sequence version replaced XP_430513.2. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001182367", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSG9", "url": "https://www.uniprot.org/uniprotkb/E1BSG9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC427470", "url": "https://www.uniprot.org/uniprotkb/E1BSG9", "locus": {} } ], "crossref": [ { "id": "E1BSG9", "url": "https://alphafold.ebi.ac.uk/entry/E1BSG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "427470", "url": "https://www.ncbi.nlm.nih.gov/gene/427470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427470", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427470", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRREVFC", "url": "https://omabrowser.org/oma/group/MRREVFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSG9", "url": "https://www.orthodb.org/?gene=E1BSG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR40387", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40387", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR40387:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40387:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27680", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27680", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001182367", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182367", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BSG9", "url": "https://www.uniprot.org/uniprotkb/E1BSG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSG9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSQYMRHEVRGCETSNLRNFWEKTIEQQTRYLQIEKERQQRSALTKLRNEWMERLEKRIKMLRTQPEDASS", "length": 72, "header": "tr|E1BSG9-1|E1BSG9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC427470 PE=4 SV=1 CANONICAL=E1BSG9-1" }, "isoforms": [ { "isoform_ac": "E1BSG9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSG9/entry#E1BSG9-1", "sequence": { "sequence": "MNSQYMRHEVRGCETSNLRNFWEKTIEQQTRYLQIEKERQQRSALTKLRNEWMERLEKRIKMLRTQPEDASS", "length": 72, "header": "tr|E1BSG9-1|E1BSG9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC427470 PE=4 SV=1 CANONICAL=E1BSG9-1" }, "locus": { "chromosome": "Z", "start_pos": 43002996, "end_pos": 43001668, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010021179.1", "url": "https://www.ensembl.org/id/ENSGALT00010021179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012118.1", "url": "https://www.ensembl.org/id/ENSGALP00010012118.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427470", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427470", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GVZ2-1", "protein_name": "Protein FAM240B", "gene_name": "FAM240B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNQYIRREVFCCGTCHELKSFWEKEISKQTFYRELEEDRQERSALKKLREEWRQRLERRLRMLDNPVEKEKPAHTAD", "length": 78 }, "evidence": [ { "id": "E1BSG9", "url": "https://omabrowser.org/oma/group/E1BSG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8C2MMX4-1", "protein_name": "Protein FAM240B-like", "gene_name": "LOC113831020", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNSQYMRREVFCCETCDELKSFWEKEISKQTFYRELEEDRQGRSALRKLREEWKQRLEKRLRMLDNPDNEGKHANPEN", "length": 78 }, "evidence": [ { "id": "E1BSG9", "url": "https://omabrowser.org/oma/group/E1BSG9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "J3QMB3-1", "protein_name": "Family with sequence similarity 240 member B", "gene_name": "Fam240b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSQYMRREVFCCETCDELKSFWEKEIHKQTCYRELEEDRQGRSALRKLREEWKERLEKRLRMLDNPDDKEKQANPEN", "length": 78 }, "evidence": [ { "id": "E1BSG9", "url": "https://omabrowser.org/oma/group/E1BSG9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R4M3-1", "protein_name": "Family with sequence similarity 240 member B", "gene_name": "Fam240b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSQYMRREVFCCETCDELKSFWEKEIRKQTCYRELEEDRQERSALRKLREEWKERLEKRLRMLDNPDDKETQANPES", "length": 78 }, "evidence": [ { "id": "E1BSG9", "url": "https://omabrowser.org/oma/group/E1BSG9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSG9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 72, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSG9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSG9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSH4-1", "uniprot_ac": "E1BSH4", "uniprot_id": "E1BSH4_CHICK", "mass": { "chemical_mass": 36044.0, "monoisotopic_mass": 36044.0 }, "refseq": { "ac": "NP_001264718", "name": "C1GALT1-specific chaperone 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264718" }, "gene_names": [ { "name": "C1GALT1C1", "type": "recommended", "evidence": [ { "id": "E1BSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSH4" } ] }, { "name": "C1GALT1C1", "type": "synonym", "evidence": [ { "id": "NP_001264718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264718" } ] } ], "protein_names": [ { "name": "C1GALT1 specific chaperone 1", "type": "synonym", "evidence": [ { "id": "E1BSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSH4/entry#names_and_taxonomy" } ] }, { "name": "C1GALT1-specific chaperone 1", "type": "synonym", "evidence": [ { "id": "NP_001264718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264718" } ] }, { "name": "core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 2", "type": "synonym", "evidence": [ { "id": "NP_001264718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264718" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01000178.1, BX931310.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Apr 20, 2013 this sequence version replaced XP_420333.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001264718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264718" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSH4", "url": "https://www.uniprot.org/uniprotkb/E1BSH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1GALT1C1", "url": "https://www.uniprot.org/uniprotkb/E1BSH4", "locus": { "chromosome": "4", "start_pos": 16348612, "end_pos": 16337938, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012234", "url": "https://www.ensembl.org/id/ENSGALG00010012234" } ] } } ], "crossref": [ { "id": "E1BSH4", "url": "https://alphafold.ebi.ac.uk/entry/E1BSH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008513", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008513", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422362", "url": "https://www.ncbi.nlm.nih.gov/gene/422362", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422362", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422362", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVMMRKA", "url": "https://omabrowser.org/oma/group/WVMMRKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSH4", "url": "https://www.orthodb.org/?gene=E1BSH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23033:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23033:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-913709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BSH4", "url": "https://www.uniprot.org/uniprotkb/E1BSH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSH4-1", "url": "https://www.uniprot.org/uniprotkb/E1BSH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSESSSFMKGVLLGGIFCVVVTLLGHVKIGHGTRAHHHEHHHIQAPNKEEVLNLSEDEQLELSQSIRVYCIVLVKPKDIGHWAAVKETWSKHCDKAEFYSSEDVKVFNAVVLNTNDMWTMMRKAYKITYERYKDEFNWFFLAYPTTFAIIENLKYFLLKKDPAQPFYIGHTMKSGDLEYVDGEGGIVLSIESLRRLSHVFEDSDKCPEQGGMIWKLSEDKQLAVCLKYTGVIAENAEDSEGKDVFNTKSVNALIKEAMASRPEQVVDGCCSDMAITFNGLSPNHMHVMMYGVYRLRPYGHTYSDALVFLPPAGSDND", "length": 318, "header": "tr|E1BSH4-1|E1BSH4_CHICK Isoform 1 of C1GALT1 specific chaperone 1 OS=Gallus gallus OX=9031 GN=C1GALT1C1 PE=3 SV=2 CANONICAL=E1BSH4-1" }, "isoforms": [ { "isoform_ac": "E1BSH4-1", "url": "https://www.uniprot.org/uniprotkb/E1BSH4/entry#E1BSH4-1", "sequence": { "sequence": "MLSESSSFMKGVLLGGIFCVVVTLLGHVKIGHGTRAHHHEHHHIQAPNKEEVLNLSEDEQLELSQSIRVYCIVLVKPKDIGHWAAVKETWSKHCDKAEFYSSEDVKVFNAVVLNTNDMWTMMRKAYKITYERYKDEFNWFFLAYPTTFAIIENLKYFLLKKDPAQPFYIGHTMKSGDLEYVDGEGGIVLSIESLRRLSHVFEDSDKCPEQGGMIWKLSEDKQLAVCLKYTGVIAENAEDSEGKDVFNTKSVNALIKEAMASRPEQVVDGCCSDMAITFNGLSPNHMHVMMYGVYRLRPYGHTYSDALVFLPPAGSDND", "length": 318, "header": "tr|E1BSH4-1|E1BSH4_CHICK Isoform 1 of C1GALT1 specific chaperone 1 OS=Gallus gallus OX=9031 GN=C1GALT1C1 PE=3 SV=2 CANONICAL=E1BSH4-1" }, "locus": { "chromosome": "4", "start_pos": 16340168, "end_pos": 16339215, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029326.1", "url": "https://www.ensembl.org/id/ENSGALT00010029326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017028.1", "url": "https://www.ensembl.org/id/ENSGALP00010017028.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422362", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422362", "resource": "KEGG Pathway" }, { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7K2E2-1", "protein_name": "C1GALT1-specific chaperone 1", "gene_name": "C1galt1c1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEIEYLFNLKSFVMARGKMLSESSSFLKGVMLGSIFYALITTLGHIRIGHRNRTHHHEHHHLQAPNKEDISKISAAERMELSKSFRVYCIVLVKPKDVSLWAAVKETWTKHCDKAEFFSSENVKVFESINVDTDDMWLMMRKAYKYAFDKYKEQYNWFFLARPSTFAVIENLKYFLLKKDPSQPFYLGHTVKSGDLEYVSVDGGIVLSIESMKRLNSLLSVPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDADRKDVFNTKSVGLFIKEAMSNHPNQVVEGCCSNMAVTFNGLTPNQMHVMMYGVYRLRAFGHVFNDALVFLPPNGSDND", "length": 336 }, "evidence": [ { "id": "E1BSH4", "url": "https://omabrowser.org/oma/group/E1BSH4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7FBK8-1", "protein_name": "C1GALT1-specific chaperone 1", "gene_name": "c1galt1c1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSEGSSFMKGMIFGGIFCLIMSFFETFNPGTHSEGHNHLHHHLKPVSKDELQKLSESQMSEFAMQVRVYCLIMVTPKLLVHWATANDTWSKHCDKSVFYTSEASKALDAVDLQEQDEWTRLRKAIQHAYENAGDLHWFFIARPTTFAIIENLKYLVLDKDPSQPFYIGHTEKSGELDYVEYDSGIVLSYEAMRRLMEVFKDEDKCPERGRALWKMSEEKQLATCLKYSGVFAENGEDAQGKGLFNKKSVSSLISDSISQNPGDVVEACCSDMAITFAGMSPSQIQVLMYGVYRLRPYGHDFHDSLTFLPPKDSDND", "length": 317 }, "evidence": [ { "id": "E1BSH4", "url": "https://omabrowser.org/oma/group/E1BSH4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RUC2-1", "protein_name": "C1GALT1-specific chaperone 1", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSESSSFLKGVMLGSIFCALITTLGHIRIFHGNRMHHHEHHHLQAPNKEDILKISEDERMELSKSFQVYCIILVKPKDVSLWAAVKETWTKHCDQAEFFSSENVKVFESINMETNDMWLMMRKAYKYAFDKYRDQYNWFFLARPTTFAIIENLKYFLLKKDPSQPFYLGHTVKSGDLEYVSVEGGIVLSIESMKRLNSLLDIPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDAEGKDVFNTKSVGLFIKEAMTNHPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHIFSDALIFLPPNGSDND", "length": 318 }, "evidence": [ { "id": "E1BSH4", "url": "https://omabrowser.org/oma/group/E1BSH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3SX46-1", "protein_name": "C1GALT1-specific chaperone 1", "gene_name": "C1GALT1C1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSESSSFLKGVMLGSIFCALITMLGHIRIGHGSRMHHHEHHHLQAPNKEDILKISEDERMELSKSFRVYCILLVRPKDVSLWAAVKETWTNHCDKVDFFSSENVKVFESINMETNDMWLMMRKAYKYAFDKYRDQYNWFFLARPTTFAIIENLKYFLLKKDPSQPFYLGHTVKSGDLEYVSMEGGIVLSIESMKRLNSLLSIPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDSEGKDIFNTKSVGLFIKEAMTNHPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHVFNDALVFLPPNGSDND", "length": 318 }, "evidence": [ { "id": "E1BSH4", "url": "https://omabrowser.org/oma/group/E1BSH4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q499P3-1", "protein_name": "C1GALT1-specific chaperone 1", "gene_name": "C1galt1c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSESSSFLKGVMLGSIFCALITMLGHIRIGNRMHHHEHHHLQAPNKDDILKISETERMELSKSFQVYCIVLVKPKDVSLWAAVKETWTKHCDKAEFFSSENVKVFESINMDTNDMWLMMRKAYKYAYDKYKDQYNWFFLARPTTFAVIENLKYFLLRKDPSQPFYLGHTVKSGDLEYVSVDGGIVLSIESMKRLNGLLSVPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDADGKDVFNTKSVGLFIKEAMTNQPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHVFNDALVFLPPNGSEND", "length": 316 }, "evidence": [ { "id": "E1BSH4", "url": "https://omabrowser.org/oma/group/E1BSH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96EU7-1", "protein_name": "C1GALT1-specific chaperone 1", "gene_name": "C1GALT1C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSESSSFLKGVMLGSIFCALITMLGHIRIGHGNRMHHHEHHHLQAPNKEDILKISEDERMELSKSFRVYCIILVKPKDVSLWAAVKETWTKHCDKAEFFSSENVKVFESINMDTNDMWLMMRKAYKYAFDKYRDQYNWFFLARPTTFAIIENLKYFLLKKDPSQPFYLGHTIKSGDLEYVGMEGGIVLSVESMKRLNSLLNIPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDADGKDVFNTKSVGLSIKEAMTYHPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHIFNDALVFLPPNGSDND", "length": 318 }, "evidence": [ { "id": "E1BSH4", "url": "https://omabrowser.org/oma/group/E1BSH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JMG2-1", "protein_name": "C1GALT1-specific chaperone 1", "gene_name": "C1galt1c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSESSSFLKGVMLGSIFCALITMLGHIRIGNRMHHHEHHHLQAPNKDDISKISEAERMELSKSFRVYCIVLVKPKDVSLWAAVKETWTKHCDKAEFFSSENVKVFESINMDTNDMWLMMRKAYKYAYDQYRDQYNWFFLARPTTFAVIENLKYFLLKKDQSQPFYLGHTVKSGDLEYVSVDGGIVLSIESMKRLNSLLSVPEKCPEQGGMIWKISEDKQLAVCLKYAGVFAENAEDADGKDVFNTKSVGLFIKEAMTNQPNQVVEGCCSDMAVTFNGLTPNQMHVMMYGVYRLRAFGHVFNDALVFLPPNGSEND", "length": 316 }, "evidence": [ { "id": "E1BSH4", "url": "https://omabrowser.org/oma/group/E1BSH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BSH4", "url": "https://www.uniprot.org/uniprotkb/E1BSH4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein O-linked glycosylation", "id": "GO:0006493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006493", "evidence": [ { "database": "UniProtKB", "id": "E1BSH4", "url": "https://www.uniprot.org/uniprotkb/E1BSH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSH4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 318, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSH4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSH4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSL8-1", "uniprot_ac": "E1BSL8", "uniprot_id": "E1BSL8_CHICK", "mass": { "chemical_mass": 200246.0, "monoisotopic_mass": 200246.0 }, "refseq": { "ac": "XP_015130472", "name": "sodium leak channel non-selective protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130472" }, "gene_names": [ { "name": "NALCN", "type": "recommended", "evidence": [ { "id": "E1BSL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ] }, { "name": "NALCN", "type": "synonym", "evidence": [ { "id": "XP_015130472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130472" } ] } ], "protein_names": [ { "name": "Sodium leak channel NALCN", "type": "recommended", "evidence": [ { "id": "E1BSL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSL8/entry#names_and_taxonomy" } ] }, { "name": "Sodium leak channel non-selective protein", "type": "synonym", "evidence": [ { "id": "E1BSL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSL8/entry#names_and_taxonomy" } ] }, { "name": "Voltage gated channel-like protein 1", "type": "synonym", "evidence": [ { "id": "E1BSL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSL8/entry#names_and_taxonomy" } ] }, { "name": "sodium leak channel non-selective protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015130472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130472" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130472" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NALCN", "url": "https://www.uniprot.org/uniprotkb/E1BSL8", "locus": { "chromosome": "1", "start_pos": 143743258, "end_pos": 143530042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005219", "url": "https://www.ensembl.org/id/ENSGALG00010005219" } ] } } ], "crossref": [ { "id": "ENSGALG00000016868", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016868", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418770", "url": "https://www.ncbi.nlm.nih.gov/gene/418770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418770", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TLFIAWN", "url": "https://omabrowser.org/oma/group/TLFIAWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TYI8", "url": "https://www.orthodb.org/?gene=A0A3Q2TYI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFK3", "url": "https://www.orthodb.org/?gene=A0A8V0XFK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XJQ0", "url": "https://www.orthodb.org/?gene=A0A8V0XJQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSL8", "url": "https://www.orthodb.org/?gene=E1BSL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46141", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46141", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46141:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46141:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015130472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130472", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TYI8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TYI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSL8-1", "url": "https://www.uniprot.org/uniprotkb/E1BSL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAEIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVTDDTQPGNVTWNNLAIPDTHCSRELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTSCLLRRLPSASSSSCDHSKRSAIEENKYIDQKLRKSVFSIRARNLLEKETAINKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAKSGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHIISREDCHGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDVTQHPFFKRTIAVLVLAQSVLLSVKWDAADPVTVPLATMSVVFTFIFVLEVTMKIIAMSPSGFWQSRRNRYDLLVTSLGVIWVILHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSTYWKTDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDMNAINQDNSAQPETSSQQQLLSPTLSDRGGYRQDSADAGKPQWKIRPRCLPSSPKPRSHPGSSVNLRSGGCLTVKSVGCKMNPMSDAASCGSEVKKWWTRQLTVESDESGEDLLDI", "length": 1738, "header": "tr|E1BSL8-1|E1BSL8_CHICK Isoform 1 of Sodium leak channel NALCN OS=Gallus gallus OX=9031 GN=NALCN PE=3 SV=3 CANONICAL=E1BSL8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TYI8-1", "url": "https://www.uniprot.org/uniprotkb/E1BSL8/entry#A0A3Q2TYI8-1", "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAEIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVTDDTQPGNVTWNNLAIPDTHCSRELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTSCLLRRLPSASSSSCDHSKRSAIEENKYIDQKLRKSVFSIRARNLLEKETAINKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNADLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAKSGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHIISREDCHGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDVTQHPFFKRTIAVLVLAQSVLLSVKWDAADPVTVPLATMSVVFTFIFVLEVTMKIIAMSPSGFWQSRRNRYDLLVTSLGVIWVILHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSTYWKTDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDMNAINQDNSAQPETSSQQQLLSPTLSDRGGYRQDSADAGKPQWKIRPRCLPSSPKPRSHPGSSVNLRSGGCLTVKSVGCKMNPMSDAASCGSEVKKWWTRQLTVESDESGEDLLDI", "length": 1719, "header": "tr|A0A3Q2TYI8-1|A0A3Q2TYI8_CHICK Computationally mapped isoform of Sodium leak channel NALCN OS=Gallus gallus OX=9031 GN=NALCN PE=3 SV=1 CANONICAL=E1BSL8-1" }, "locus": { "chromosome": "1", "start_pos": 143742254, "end_pos": 143539779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012353.1", "url": "https://www.ensembl.org/id/ENSGALT00010012353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006917.1", "url": "https://www.ensembl.org/id/ENSGALP00010006917.1" } ] } }, { "isoform_ac": "A0A8V0XFK3-1", "url": "https://www.uniprot.org/uniprotkb/E1BSL8/entry#A0A8V0XFK3-1", "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAEIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVTDDTQPGNVTWNNLAIPDTHCSRELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLRKSVFSIRARNLLEKETAINKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNADLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAKSGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHIISREDCHGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDVTQHPFFKRTIAVLVLAQSVLLSVKWDAADPVTVPLATMSVVFTFIFVLEVTMKIIAMSPSGFWQSRRNRYDLLVTSLGVIWVILHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSTYWKTDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDMNAINQDNSAQPETSSQQQLLSPTLSDRGGYRQDSADAGKPQWKIRPRCLPSSPKPRSHPGSSVNLRSGGCLTVKSVGCKMNPMSDAASCGSEVKKWWTRQLTVESDESGEDLLDI", "length": 1626, "header": "tr|A0A8V0XFK3-1|A0A8V0XFK3_CHICK Computationally mapped isoform of Sodium leak channel NALCN OS=Gallus gallus OX=9031 GN=NALCN PE=3 SV=1 CANONICAL=E1BSL8-1" }, "locus": { "chromosome": "1", "start_pos": 143742254, "end_pos": 143539779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012355.1", "url": "https://www.ensembl.org/id/ENSGALT00010012355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006919.1", "url": "https://www.ensembl.org/id/ENSGALP00010006919.1" } ] } }, { "isoform_ac": "A0A8V0XJQ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BSL8/entry#A0A8V0XJQ0-1", "sequence": { "sequence": "MLAWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAEIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVTDDTQPGNVTWNNLAIPDTHCSRELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTSCLLRRLPSASSSSCDHSKRSAIEENKYIDQKLRKSVFSIRARNLLEKETAINKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNADLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAKSGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHIISREDCHGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDVTQHPFFKRTIAVLVLAQSVLLSVKWDAADPVTVPLATMSVVFTFIFVLEVTMKIIAMSPSGFWQSRRNRYDLLVTSLGVIWVILHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSTYWKTDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDMNAINQDNSAQPETSSQQQLLSPTLSDRGGYRQDSADAGKPQWKIRPRCLPSSPKPRSHPGSSVNLRSGGCLTVKSVGCKMNPMSDAASCGSEVKKWWTRQLTVESDESGEDLLDI", "length": 1686, "header": "tr|A0A8V0XJQ0-1|A0A8V0XJQ0_CHICK Computationally mapped isoform of Sodium leak channel NALCN OS=Gallus gallus OX=9031 GN=NALCN PE=3 SV=1 CANONICAL=E1BSL8-1" }, "locus": { "chromosome": "1", "start_pos": 143742254, "end_pos": 143530133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012359.1", "url": "https://www.ensembl.org/id/ENSGALT00010012359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006923.1", "url": "https://www.ensembl.org/id/ENSGALP00010006923.1" } ] } }, { "isoform_ac": "E1BSL8-1", "url": "https://www.uniprot.org/uniprotkb/E1BSL8/entry#E1BSL8-1", "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPKTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIAEIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVTDDTQPGNVTWNNLAIPDTHCSRELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVAVDVIVAASNYYKGENFKRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTSCLLRRLPSASSSSCDHSKRSAIEENKYIDQKLRKSVFSIRARNLLEKETAINKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAKSGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPHIISREDCHGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDVTQHPFFKRTIAVLVLAQSVLLSVKWDAADPVTVPLATMSVVFTFIFVLEVTMKIIAMSPSGFWQSRRNRYDLLVTSLGVIWVILHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDNSTYWKTDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDMNAINQDNSAQPETSSQQQLLSPTLSDRGGYRQDSADAGKPQWKIRPRCLPSSPKPRSHPGSSVNLRSGGCLTVKSVGCKMNPMSDAASCGSEVKKWWTRQLTVESDESGEDLLDI", "length": 1738, "header": "tr|E1BSL8-1|E1BSL8_CHICK Isoform 1 of Sodium leak channel NALCN OS=Gallus gallus OX=9031 GN=NALCN PE=3 SV=3 CANONICAL=E1BSL8-1" }, "locus": { "chromosome": "1", "start_pos": 143742254, "end_pos": 143539779, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012347.1", "url": "https://www.ensembl.org/id/ENSGALT00010012347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006911.1", "url": "https://www.ensembl.org/id/ENSGALP00010006911.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418770", "resource": "KEGG Pathway" }, { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZM83-1", "protein_name": "Sodium leak channel NALCN", "gene_name": "NALCN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQQMMRSSVFHMFILSMVTVDVIVAASNYHKGESFKRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTCCLLRSLPSASSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLLVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPMHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDQNANSQENNVQPETSSQQQLLSPTLSDRGGSRQDAAEAGKPQRKFGQWRLPSAPKPISHSVSSVNLRFGGRTTMKSVVCKMNPMADTASCGSEVKKWWTRQLTVESDESGDDLLDI", "length": 1738 }, "evidence": [ { "id": "E1BSL8", "url": "https://omabrowser.org/oma/group/E1BSL8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2BF56-1", "protein_name": "Sodium leak channel NALCN", "gene_name": "nalcn", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCSAGAISALLFPLIHSLYSTASPSMLKRKQSSRVEAQPMTDFGPDETLTDSADILWINKPWVHSLLRACAIISVISVCMNTPKTFEHYPPLQYVTFALDTLLMFLYTAEMIAKMHIRGIIKGENSYVKDRWCMFDGFMVVFLWVSLVLQVFEIAELVDQMSPWGMLRIPRALIMIRVFRIYFRFELPRSRITNILKRSGEQIWSVTIFLLFFLLLYGILGVQMFGTFNHHCVTNETEKEKVTWNSLAIPDTHCSPNGEGYQCPVGFKCVDLEDYGLSRQELGYSGFNELGTSIFTVYEAASQEGWVFIMYRAIDSFPRWRSYFYFLTLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDASGGWQLVAVDVNKPHGRAPACLQQLMRSSVFHMFILSMVAVDVIVAASNYHRGDHKLTNDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFESLLVVGTTLHIYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEDLDRFTTFPRAFMSMFQILTQEGWVDVMDQTLVAVGQMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPRIRESFMKQFIDRQQQDPSCLFRRLPSASSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLMEKEITVNKILRACTRQRMLSGSFEGQPTKERSILSVQHHIRQERRSLRHGSTSQRISRGKSLETLTQDHSSTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRMIVRARFNASNTDPNTGAVNSTKYHQLYDLLGLVTYLDWVMIVVTICSCISMMFESPFTRVMHVPTLQIGEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWLPNNVPPESGAQLLMMLRCFRPLRIFKLVPQMRKVVREVLKGFKEIFLVSILLLTLMLVFATFGVQLFAGKLAKCNDPHISSKDDCHGIFRINVSISKNLNLKLKDGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPENGGFRAKMYDITQHPFFKRGIAVLVLAQSVLLSVKWDELGAVTFPLATMSVVFTFIFVLEVTMKLIAMSPAGYWQSRRNRYDLLVTSLGLIWIILHFALQNAYTYMMGTCVIVFRFFTICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSTAGKAITVLIRIVTGEDWNKIMHDCMVQPPFCTPDKHRYWETDCGNYAGALIYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTSRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIILSLRESQQQDLRRLLNPPSIETTVPSEDTNTHNQDNPTQPEQNSGLQTLLSPTLSDRSGYRQDSADRPQRKLGQWRLPAGRTSVKSMVCKMNPVTDEASSGSEVKKWWTRQLTVESDESGDDLIDI", "length": 1743 }, "evidence": [ { "id": "E1BSL8", "url": "https://omabrowser.org/oma/group/E1BSL8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A8JUW5-1", "protein_name": "Sodium leak channel NALCN", "gene_name": "na", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIDRLQIRRLGAAARNKRAGGGGGAGGGAVGSGGAGGGGGGGGAGAVPGAAGAAGTGPITGASATAASGSSGSGGHHQHHHHSHPYSTSGINTPATASTSSSSGNSLTPQQQQQQQHPHHQSHHGHHYAHHQQHTHHHAPPHSHHPHPHPHGHPHSYPHLRHSQPASASQFSFNPSPGSSPGNGLGLGARQDAASALNSPTTIVNSGSGSGGGSSVAFGMQPQQQQQSLAGGGGGGSSATAAPSSGGGHNNGAGLGPVVGGGGGGLNLLGGLGGMGGMGGGAAAAGMGICGGISSTVGSAAITGVPPIGLGIATGIGNKIMLGRKQSLKGGEPFLADYGPEESLNESADIEWVNKLWVRRLMRLCALVSLTSVSLNTPKTFERYPSLQFITFASDTAVTLLFTAEMIAKMHIRGVLHGEVPYLKDHWCQFDASMVSFLWISIILQIFEVLEIVPKFSYLSIMRAPRPLIMIRFLRVFLKFSMPKSRINQIFKRSSQQIYNVTLFFLFFMSLYGLLGVQFFGELKNHCVMNNTEYDLYKRPILTINSLAIPDTFCSMDPDSGYQCSPGMVCMKMDFLSSYVIGFNGFEDIATSIFTVYQAASQEGWVFIMYRAIDSLPAWRAAFYFSTMIFFLAWLVKNVFIAVITETFNEIRVQFQQMWGARGHIQKTAASQILSGNDTGWRLVTIDDNKHGGLAPETCHAILRSPYFRMLVMSVILANGIVTATMTFKHDGRPRDVFYERYYYIELVFTCLLDLETLFKIYCLGWRGYYKHSIHKFELLLAAGTTLHIVPMFYPSGLTYFQVLRVVRLIKASPMLEGFVYKIFGPGKKLGSLIIFTMCLLIISSSISMQLFCFLCDFTKFESFPEAFMSMFQILTQEAWVEVMDETMIRTSKTLTPLVAVYFILYHLFVTLIVLSLFVAVILDNLELDEDIKKLKQLKFREQSAEIKETLPFRLRIFEKFPDSPQMTILHRIPNDFMLPKVRESFMKHFVIELETEDSLVENCKRPMSECWESNVVFRKQKPVRIMNKTAKVRAAGSSLRKLAITHIINDSNNQRLMLGDSAMLPVVGTKGGGGLKSQGTITHSKPWRVDQKKFGSRSIRRSVRSGSIKLKQTYEHLMENGDIAAAPRANSGRARPHDLDIKLLQAKRQQAEMRRNQREEDLRENHPFFDTPLFLVPRESRFRKICQKIVHARYDARLKDPLTGKERKVQYKSLHNFLGLVTYLDWVMIFATTLSCISMMFETPNYRVMDHPTLQIAEYGFVIFMSLELALKILADGLFFTPKAYIKDVAAALDVFIYVVSTSFLCWMPLNIPTNSAAQLLMILRCVRPLRIFTLVPHMRKVVYELCRGFKEILLVSTLLILLMFIFASYGVQLYGGRLARCNDPTISRREDCVGVFMRRVFVTKMKLTPGPDESYPAMLVPRVWANPRRFNFDNIGDAMLTLFEVLSFKGWLDVRDVLIKAVGPVHAVYIHIYIFLGCMIGLTLFVGVVIANYSENKGTALLTVDQRRWCDLKKRLKIAQPLHLPPRPDGRKIRAFTYDITQHIIFKRVIAVVVLINSMLLSITWIKGEVHTERLVIVSAVLTFVFVVEVVMKNIAFTPRGYWQSRRNRYDLLVTVAGVIWIILQTILRNDLSYFFGFMVVILRFFTITGKHTTLKMLMLTVGVSVCKSFFIIFGMFLLVFFYALAGTILFGTVKYGEGIGRRANFGSPVTGVAMLFRIVTGEDWNKIMHDCMVQPPYCTLGNNYWETDCGNFTASLIYFCTFYVIITYIVLNLLVAIIMENFSLFYSNEEDALLSYADIRNFQNTWNIVDIHQRGVIPVRRVKFILRLLKGRLECDPQKDRLLFKYMCYELDKLHNGEDVTFHDVINMLSYRSVDIRKALQLEELLAREEFEYLVEEEVAKMTIRTWLEGCLKKIRAQNASKQQNSLIAGLRATNEQPVMRPNIQEDKAPLGAVDKSAISTISGAVAGACPPTSDAFSPTFSSTENEEKDGSSSAVVQLPHSETSIAGTGSSATGAATATGTSSGLGVGPPTVQSTARHVMTVGKRGYALNRSDSTGSSAGRKFLAPTSSDPQQRSTLSDKERLHITSQQRKKNSMTTLPHAGQLGQLAKQRGGGGEATKSSSFFAQLNSEIGQFHYPTINAAAAAAALHGYGHGHGHGHGGHGGHGGHGEHQMHHHHGGALGSPSAMMSQMIGGSGKLLPFNNQANAVYEVHDWWQEQVLCPQTSDDEI", "length": 2233 }, "evidence": [ { "id": "E1BSL8", "url": "https://omabrowser.org/oma/group/E1BSL8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P50077-1", "protein_name": "Calcium-channel protein CCH1", "gene_name": "CCH1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQGRKRTLTEPFEPNTNPFGDNAAVMTENVEDNSETDGNRLESKPQALVPPALNIVPPESSIHSTEEKKGDEYNGNDKDSSLISNIFRTRVGRSSHENLSRPKLSLKTASFGAAESSRRNVSPSTKSAKSSSQYIDLNDERLRRRSFSSYSRSSSRRVSNSPSSTDRPPRSAKVLSLIAADDMDDFEDLQKGFKSAIDEEGLTWLPQLKSEKSRPVSDVGEDRGEGEQESIPDVHTPNVGASATPGSIHLTPEPAQNGSVSEGLEGSINNSRKKPSPKFFHHLSPQKEDKDQTEVIEYAEDILDFETLQRKLESRPFVLYGHSLGVFSPTNPLRIKIARFLLHRRYSLLYNTLLTFYAILLAIRTYNPHNVVFLYRFSNWTDYFIFILSACFTGNDIAKIIAFGFWDDSEMFKAYGREYKSILQRSGIMKLYIYLREKYGRKLIDFIIPFRIISPGEETKYQRSSLSTSLTKPYGAKENQRPFGTPRAFARSSWNRIDLVSSVSFWLGMFLSIKSYDTKTGIRIFKPLAILRILRLVNVDTGMPSILRGLKYGIPQLVNVSSMLVYFWIFFGILGVQIFQGSFRRQCVWFNPEDPTDTYQYDMQFCGGYLDPVTKRKQNYIYEDGSEGSVSKGFLCPQYSKCVSNANPYNGRISFDNIVNSMELVFVIMSANTFTDLMYYTMDSDEMAACLFFIVCIFVLTIWLLNLLIAVLVSSFEIANEEYKKKKFIYGSRKTGYVARIVTGYWKYFKLKANQTKFPNWSQKGLAIYSHVEFIFVILIICDIGMRASVKVSTSANCNNILLKTDRGISIVLFIESLARLVLYLPNMWKFLTKPSYVYDFIISIITLVISCLAVEGVLGHMYAWLSIFHISRFYRVIISFNLTKKLWKQILSNGVMIWNLSSFYFFFTFLVAIIMAVYFEGVIPPEEMADQPFGMYSLPNSFLSLFIIGSTENWTDILYALQKHSPNISSTFFCSVFFIIWFLLSNSVILNIFIALISESMEVKEEEKRPQQIKHYLKFVYPQKIQEYTHASLVARIRKKFFGGHRNEDTRDFKQFLMRGTAIMNIAQNMGELADEFKEPPSENLFKKGLSKLTIGVPSLKRLRMFANNPFYKNSDVVFTETNDINGRTYILELNEYEDEKLDYLKKYPLFNYSYYFFSPQHRFRRFCQRLVPPSTGKRTDGSRFFEDSTDLYNKRSYFHHIERDVFVFIFALATILLIVCSCYVTPLYRMHHKMGTWNWSSALDCAFIGAFSIEFIVKTVADGFIYSPNAYLRNPWNFIDFCVLISMWINLIAYLKNNGNLSRIFKGLTALRALRCLTISNTARQTFNLVMFDGLNKIFEAGLISLSLLFPFTVWGLSIFKGRLGTCNDGSLGRADCYNEYSNSVFQWDIMSPRVYQQPYLHLDSFASAFSSLYQIISLEGWVDLLENMMNSSGIGTPATVMGSAGNALFLVLFNFLSMVFILNLFVSFIVNNQARTTGSAYFTIEEKAWLESQKLLSQAKPKAIPNLIELSRVRQFFYQLAVEKKNFYYASFLQVVLYLHIIMLLSRSYNPGNLIGYQGVYFMFSTSVFLIQEALHMCGEGPRLYFRQKWNSIRLSIIIIAFIMNAVAFHVPASHYWFHNIKGFFLLVIFLFIIPQNDTLTELLETAMASLPPILSLTYTWGVLFLVYAIALNQIFGLTRLGSNTTDNINFRTVIKSMIVLFRCSFGEGWNYIMADLTVSEPYCSSDDNSTYTDCGSETYAYLLLMSWNIISMYIFVNMFVSLIIGNFSYVYRSGGSRSGINRSEIKKYIEAWSKFDTDGTGELELSYLPRIMHSFDGPLSFKIWEGRLTIKSLVENYMEVNPDDPYDVKIDLIGLNKELNTIDKAKIIQRKLQYRRFVQSIHYTNAYNGCIRFSDLLLQIPLYTAYSARECLGIDQYVHHLYILGKVDKYLENQRNFDVLEMVVTRWKFHCRMKRTIEPEWDVKDPTVSSHISNINVNLEPAPGILEREPIATPRMDYGVNNFMWSPRMNQDSTMEPPEEPIDNNDDSANDLIDR", "length": 2039 }, "evidence": [ { "id": "E1BSL8", "url": "https://omabrowser.org/oma/group/E1BSL8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6Q760-1", "protein_name": "Sodium leak channel NALCN", "gene_name": "Nalcn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVIPVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTCCLFRILPSTSSSSCDNPKRPTVEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPTKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDTNANSQDHNTQPESSSQQQLLSPTLSDRGGSRQDAADTGKPQRKIGQWRLPSAPKPISHSVSSVNLRFGGRTTMKSVVCKMNPMPDTASCGSEVKKWWTRQLTVESDESGDDLLDI", "length": 1738 }, "evidence": [ { "id": "E1BSL8", "url": "https://omabrowser.org/oma/group/E1BSL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BXR5-1", "protein_name": "Sodium leak channel NALCN", "gene_name": "Nalcn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEASSQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGTRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPLVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTCCLFRILPSTSSSSCDNPKKPTAEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMITVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVDDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQEQERSRFLNPPSIETTQPSEDSNANSQDHSMQPETSSQQQLLSPTLSDRGGSRQDAADTGKPQRKIGQWRLPSAPKPISHSVSSVNLRFGGRTTMKTVVCKMNPMPDTASCGSEVKKWWTRQLTVESDESGDDLLDI", "length": 1738 }, "evidence": [ { "id": "E1BSL8", "url": "https://omabrowser.org/oma/group/E1BSL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZF0-1", "protein_name": "Sodium leak channel NALCN", "gene_name": "NALCN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTCCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDTNANSQDNSMQPETSSQQQLLSPTLSDRGGSRQDAADAGKPQRKFGQWRLPSAPKPISHSVSSVNLRFGGRTTMKSVVCKMNPMTDAASCGSEVKKWWTRQLTVESDESGDDLLDI", "length": 1738 }, "evidence": [ { "id": "E1BSL8", "url": "https://omabrowser.org/oma/group/E1BSL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of synaptic transmission, cholinergic", "id": "GO:0032224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032224", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" }, { "name": "positive regulation of synaptic transmission, GABAergic", "id": "GO:0032230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032230", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" }, { "name": "regulation of neuronal action potential", "id": "GO:0098908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098908", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" }, { "name": "monoatomic ion channel complex", "id": "GO:0034702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034702", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" }, { "name": "voltage-gated sodium channel activity", "id": "GO:0005248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005248", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" }, { "name": "sodium channel activity", "id": "GO:0005272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005272", "evidence": [ { "database": "UniProtKB", "id": "E1BSL8", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1371, "end_pos": 1373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1409, "end_pos": 1411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1449, "end_pos": 1451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 859, "end_pos": 861, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BSL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSL8" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 331, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 1371, "end_pos": 1373 }, { "start_pos": 1409, "end_pos": 1411 }, { "start_pos": 1449, "end_pos": 1451 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 859, "end_pos": 861 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSS9-1", "uniprot_ac": "E1BSS9", "uniprot_id": "E1BSS9_CHICK", "mass": { "chemical_mass": 67207.0, "monoisotopic_mass": 67207.0 }, "refseq": { "ac": "XP_416178", "name": "solute carrier family 23 member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416178" }, "gene_names": [ { "name": "LOC417937", "type": "recommended", "evidence": [ { "id": "E1BSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSS9" } ] }, { "name": "LOC417937", "type": "synonym", "evidence": [ { "id": "XP_416178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416178" } ] } ], "protein_names": [ { "name": "Solute carrier family 23 member 1", "type": "recommended", "evidence": [ { "id": "E1BSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSS9/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 23 member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416178" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_416178.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416178", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416178" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSS9", "url": "https://www.uniprot.org/uniprotkb/E1BSS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC417937", "url": "https://www.uniprot.org/uniprotkb/E1BSS9", "locus": {} } ], "crossref": [ { "id": "E1BSS9", "url": "https://alphafold.ebi.ac.uk/entry/E1BSS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011717", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011717", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417937", "url": "https://www.ncbi.nlm.nih.gov/gene/417937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417937", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GLGFDWN", "url": "https://omabrowser.org/oma/group/GLGFDWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCQ4", "url": "https://www.orthodb.org/?gene=A0A8V0YCQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSS9", "url": "https://www.orthodb.org/?gene=E1BSS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00860", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00860", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416178", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416178", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSS9", "url": "https://www.uniprot.org/uniprotkb/E1BSS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSS9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPSTDKELNGLDNPSFMSEDESHHCASPDHAAQGPEEGKGKGQSSKLAYTVTDMPPWYLCILLGIQHFLTAMGGLVAIPLILSKELCLQHDLLTQSHLISTIFFVSGICTLLQVLFGVRLPIIQGGTFAFLTPTLAMLSLPKWKCPAWTENATLVNTSSPEFIEVWQTRMREVQGAIMVASCFQILVGFSGIIGFLMRFIGPLTIAPTITLVALPLFDSAGDKAGQHWGIAFMTIFFIVLFSQYLKDVPVPLPSFRRGKKCHFSPIYVFQIFPVLLGLSLSWLLCYVLTVTDVLPTDPTAYGHLARTDTRGDVLSQAPWFRLPYPGQWGTPTVSLAGIFGILAGVISSMLESMGDYYACARLSGAPPPPKHAINRGIGVEGIGCLLAGAWGTGNGTTSYSENVGALGITKVGSRMVIIAGACAMLLSGVFGKVGAMLASIPTPVIGGMFLVMFGIITAVGISNLQYTDMNSSRNIFIFGFSVFAGLTVPNWANKNNTLLETEIIQLDQVIQVLLTTGMFVGGLLGFILDNTIPGTQEERGLLAWKHSHKGEADNSQLISKVYDLPFGIGTKYCAVSWFRYLPACPKKVPGGKKMDELKASGQESSVKASLERDSEIGADTRI", "length": 623, "header": "tr|E1BSS9-1|E1BSS9_CHICK Isoform 1 of Solute carrier family 23 member 1 OS=Gallus gallus OX=9031 GN=LOC417937 PE=3 SV=1 CANONICAL=E1BSS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCQ4-1", "url": "https://www.uniprot.org/uniprotkb/E1BSS9/entry#A0A8V0YCQ4-1", "sequence": { "sequence": "MPPWYLCILLGIQHFLTAMGGLVAIPLILSKELCLQHDLLTQSHLISTIFFVSGICTLLQVLFGVRLPIIQGGTFAFLTPTLAMLSLPKWKCPAWTENATLVNTSSPEFIEVWQTRMREVQGAIMVASCFQILVGFSGIIGFLMRFIGPLTIAPTITLVALPLFDSAGDKAGQHWGIAFMTIFFIVLFSQYLKDVPVPLPSFRRGKKCHFSPIYVFQIFPVLLGLSLSWLLCYVLTVTDVLPTDPTAYGHLARTDTRGDVLSQAPWFRLPYPGQWGTPTVSLAGIFGILAGVISSMLESMGDYYACARLSGAPPPPKHAINRGIGVEGIGCLLAGAWGTGNGTTSYSENVGALGITKVGSRMVIIAGACAMLLSGVFGKVGAMLASIPTPVIGGMFLVMFGIITAVGISNLQYTDMNSSRNIFIFGFSVFAGLTVPNWANKNNTLLETEIIQLDQVIQVLLTTGMFVGGLLGFILDNTIPGTQEERGLLAWKHSHKGEADNSQLISKVYDLPFGIGTKYCAVSWFRYLPACPKKVPGGKKMDELKASGQESSVKASLERDSEIGADTRI", "length": 569, "header": "tr|A0A8V0YCQ4-1|A0A8V0YCQ4_CHICK Computationally mapped isoform of Solute carrier family 23 member 1 OS=Gallus gallus OX=9031 GN=LOC417937 PE=3 SV=1 CANONICAL=E1BSS9-1" }, "locus": { "chromosome": "1", "start_pos": 47926472, "end_pos": 47910048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024097.1", "url": "https://www.ensembl.org/id/ENSGALT00010024097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013731.1", "url": "https://www.ensembl.org/id/ENSGALP00010013731.1" } ] } }, { "isoform_ac": "E1BSS9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSS9/entry#E1BSS9-1", "sequence": { "sequence": "MTPSTDKELNGLDNPSFMSEDESHHCASPDHAAQGPEEGKGKGQSSKLAYTVTDMPPWYLCILLGIQHFLTAMGGLVAIPLILSKELCLQHDLLTQSHLISTIFFVSGICTLLQVLFGVRLPIIQGGTFAFLTPTLAMLSLPKWKCPAWTENATLVNTSSPEFIEVWQTRMREVQGAIMVASCFQILVGFSGIIGFLMRFIGPLTIAPTITLVALPLFDSAGDKAGQHWGIAFMTIFFIVLFSQYLKDVPVPLPSFRRGKKCHFSPIYVFQIFPVLLGLSLSWLLCYVLTVTDVLPTDPTAYGHLARTDTRGDVLSQAPWFRLPYPGQWGTPTVSLAGIFGILAGVISSMLESMGDYYACARLSGAPPPPKHAINRGIGVEGIGCLLAGAWGTGNGTTSYSENVGALGITKVGSRMVIIAGACAMLLSGVFGKVGAMLASIPTPVIGGMFLVMFGIITAVGISNLQYTDMNSSRNIFIFGFSVFAGLTVPNWANKNNTLLETEIIQLDQVIQVLLTTGMFVGGLLGFILDNTIPGTQEERGLLAWKHSHKGEADNSQLISKVYDLPFGIGTKYCAVSWFRYLPACPKKVPGGKKMDELKASGQESSVKASLERDSEIGADTRI", "length": 623, "header": "tr|E1BSS9-1|E1BSS9_CHICK Isoform 1 of Solute carrier family 23 member 1 OS=Gallus gallus OX=9031 GN=LOC417937 PE=3 SV=1 CANONICAL=E1BSS9-1" }, "locus": { "chromosome": "1", "start_pos": 47926472, "end_pos": 47907024, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024104.1", "url": "https://www.ensembl.org/id/ENSGALT00010024104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013735.1", "url": "https://www.ensembl.org/id/ENSGALP00010013735.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417937", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0J9YUX7-1", "protein_name": "Solute carrier family 23 member 4", "gene_name": "Slc23a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSAGGSCESPDCMGGDGVLSLHTEGQGKKQDGVQKDPNSNSNLAYGILDSPPWYLCIFLGIQHFLTALGGLVAVPLILAKDLCLQHDPLTQSYLISTIFFVSGICTLLQVFLGVRLPILQGGTFAFVAPSLAMLSLPAWKCPEWTLNASQVNTSSPEFIEEWQKRIRELQGAIMVASCVQMLVGFSGLIGFLMRFIGPLTIAPTISLVALPLFDSAGSDAGIHWGISALTIFLIVLFSQYLKNVMVPVPVYGRRKKCHISRFNLFQVFPVLLALCLSWLFCFVLTVTNTLPESPTAYGYMARTDTKGSVLSQAPWFRFPYPGQWGLPTISLAGVFGIIAGVISSMVESVGDYHACARLVGAPPPPKHAINRGIGIEGLGCLLAGAWGTGNGTTSYSENVGALGITRVGSRMVIVAAGCVLLVMGMFGKIGAAFATIPTPVIGGMFLVMFGIISAVGISNLQYVDMNSSRNLFVFGFSIYCGLAIPNWVNKNPEKLQTGILQLDQVIQVLLTTGMFVGGFLGFVLDNTIPGSLEERGLLAWSKIQEDSEESSKVSKVYGLPWGIGTKFCTSSCTRLLPFWPRLDHHRDEVGVSQLTLCSQTSSGNHLWSATETKM", "length": 615 }, "evidence": [ { "id": "E1BSS9", "url": "https://omabrowser.org/oma/group/E1BSS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3LAB9-1", "protein_name": "Solute carrier family 23 member 1-like", "gene_name": "LOC100525318", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNSAITSPEHPDPSWRGDGVLSSQEGSQDKKKDDQPRSPSSSHLAYSILDIPPWYLCIFLGIQHFLTALGALVAVPFILAKDLCLQHDPLTQSYLLGTIFFVSGICTLLQVFLGVRLPILQGGTFAFVAPSLAMLSLPTWKCPEWTLNASLVNTSSPEFTEEWQKRIRELQGAILVASCVQMLVGFSGLIGFLMRFIGPLTIAPTIALMALPLFDSAGNDAGIHWGIAATTIFFIVLFSQYLKNIAVPVPVYGREKKFHTSKFYLFQVFPVLLALCLSWLLCFVLTITNALPSAPTAYGYLARTDTKGNVLSQAPWFRVPYPGQWGLPTISLAGVFGIIAGVISSMVESVGDYYACARLVGAPPPPRHAINRGIGIEGLGCLLAGAWGTGNGTTSYSENVGALSITRVGSRMVIVAAGCVLLLMGVFGKIGAAFATIPTPVIGGMFLVMFGVITAVGISNLQYVDMNSSRNLFVFGFSIYCGLAVPNWVNKNPERLHTGILQLDQVIQVLLTTGMFVGGFLGFLLDNTIPGSLEERGLLAWNHIQEESEETARASEIYGLPCGIGTRFCTSACTRGLPFWPRPECGGQGEVGVSQLTLCSRDSSAERPKGAAETAM", "length": 616 }, "evidence": [ { "id": "E1BSS9", "url": "https://omabrowser.org/oma/group/E1BSS9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BSS9", "url": "https://www.uniprot.org/uniprotkb/E1BSS9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1BSS9", "url": "https://www.uniprot.org/uniprotkb/E1BSS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSS9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 623, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSS9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSS9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 157, "end_pos": 159 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 496, "end_pos": 498 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSW0-1", "uniprot_ac": "E1BSW0", "uniprot_id": "E1BSW0_CHICK", "mass": { "chemical_mass": 38275.0, "monoisotopic_mass": 38275.0 }, "refseq": { "ac": "NP_001186347", "name": "activator of 90 kDa heat shock protein ATPase homolog 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186347" }, "gene_names": [ { "name": "AHSA2", "type": "recommended", "evidence": [ { "id": "E1BSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSW0" } ] }, { "name": "AHSA2P", "type": "synonym", "evidence": [ { "id": "NP_001186347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186347" } ] }, { "name": "AHSA2", "type": "synonym", "evidence": [ { "id": "NP_001186347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186347" } ] } ], "protein_names": [ { "name": "AHA1, activator of heat shock 90kDa 2", "type": "synonym", "evidence": [ { "id": "E1BSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSW0/entry#names_and_taxonomy" } ] }, { "name": "activator of 90 kDa heat shock protein ATPase homolog 2", "type": "synonym", "evidence": [ { "id": "NP_001186347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186347" } ] }, { "name": "activator of HSP90 ATPase homolog 2, pseudogene", "type": "synonym", "evidence": [ { "id": "NP_001186347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186347" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01065156.1, HAEK01078699.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000059.1. On Jul 6, 2018 this sequence version replaced NP_001186347.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186347", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186347" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSW0", "url": "https://www.uniprot.org/uniprotkb/E1BSW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AHSA2", "url": "https://www.uniprot.org/uniprotkb/E1BSW0", "locus": { "chromosome": "3", "start_pos": 2280066, "end_pos": 2271669, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019287", "url": "https://www.ensembl.org/id/ENSGALG00010019287" } ] } } ], "crossref": [ { "id": "E1BSW0", "url": "https://alphafold.ebi.ac.uk/entry/E1BSW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004483", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004483", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08892", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08892", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421194", "url": "https://www.ncbi.nlm.nih.gov/gene/421194", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421194", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421194", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDCEVNQ", "url": "https://omabrowser.org/oma/group/GDCEVNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSW0", "url": "https://www.orthodb.org/?gene=E1BSW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13009", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13009", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13009:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13009:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1BSW0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1BSW0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001186347", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BSW0", "url": "https://www.uniprot.org/uniprotkb/E1BSW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSW0-1", "url": "https://www.uniprot.org/uniprotkb/E1BSW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKWGQGDPRWIVEERADGTNVNNWHWTERDATSWSRSKLQEVLVGLVVEGEAGRCEICELKQVEGEASCSSRKGRLIFFYEWNLRLSWKGTVKESGEKHKGSIEIPNLSEENEVDDTEINVSKKKGEGDILKELMRTEGTTKVREALRDYLKALKTEFTLGMILPTKAAGQELAAERRLSGNTVQESASPHLQGLVGVKIPTVRILMREIFSSPADELYSIFTTKELVQKFSKCPAVIEAEKGGKLLMFDGCVSGEYTELVPGKRLVLKWRCRNWPDEHYATVALNFQNMVAETELQLECKGVPVSNEDSTRQWWKKQYFEEIHNLLQQSKDNMD", "length": 336, "header": "tr|E1BSW0-1|E1BSW0_CHICK Isoform 1 of AHA1, activator of heat shock 90kDa 2 OS=Gallus gallus OX=9031 GN=AHSA2 PE=1 SV=4 CANONICAL=E1BSW0-1" }, "isoforms": [ { "isoform_ac": "E1BSW0-1", "url": "https://www.uniprot.org/uniprotkb/E1BSW0/entry#E1BSW0-1", "sequence": { "sequence": "MAKWGQGDPRWIVEERADGTNVNNWHWTERDATSWSRSKLQEVLVGLVVEGEAGRCEICELKQVEGEASCSSRKGRLIFFYEWNLRLSWKGTVKESGEKHKGSIEIPNLSEENEVDDTEINVSKKKGEGDILKELMRTEGTTKVREALRDYLKALKTEFTLGMILPTKAAGQELAAERRLSGNTVQESASPHLQGLVGVKIPTVRILMREIFSSPADELYSIFTTKELVQKFSKCPAVIEAEKGGKLLMFDGCVSGEYTELVPGKRLVLKWRCRNWPDEHYATVALNFQNMVAETELQLECKGVPVSNEDSTRQWWKKQYFEEIHNLLQQSKDNMD", "length": 336, "header": "tr|E1BSW0-1|E1BSW0_CHICK Isoform 1 of AHA1, activator of heat shock 90kDa 2 OS=Gallus gallus OX=9031 GN=AHSA2 PE=1 SV=4 CANONICAL=E1BSW0-1" }, "locus": { "chromosome": "3", "start_pos": 2279120, "end_pos": 2271789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046638.1", "url": "https://www.ensembl.org/id/ENSGALT00010046638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027776.1", "url": "https://www.ensembl.org/id/ENSGALP00010027776.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421194", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421194", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7W5-1", "protein_name": "Activator of HSP90 ATPase homolog 2", "gene_name": "Ahsa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATVWSKGKLRELLVGLAMENEAGRCEISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKGTVKESGAKHKGLIEIPSLSEENEVNDTEVNVSKKKGDGEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTKAGATQALTLERKLTENALQASPVALGVRIPTVALHLTELFDTTVEQLYSIFTVKELVQGFSKSPAVLEAEKGGKFQMFDGNITGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVPAPGQTELQLDCKGVPVCKEEHMKFCWQKQHFEEIKGLLQLTTQNA", "length": 331 }, "evidence": [ { "id": "E1BSW0", "url": "https://omabrowser.org/oma/group/E1BSW0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12449-1", "protein_name": "Hsp90 co-chaperone AHA1", "gene_name": "AHA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVVNNPNNWHWVDKNCIGWAKEYFKQKLVGVEAGSVKDKKYAKIKSVSSIEGDCEVNQRKGKVISLFDLKITVLIEGHVDSKDGSALPFEGSINVPEVAFDSEASSYQFDISIFKETSELSEAKPLIRSELLPKLRQIFQQFGKDLLATHGNDIQVPESQVKSNYTRGNQKSSFTEIKDSASKPKKNALPSSTSTSAPVSSTNKVPQNGSGNSTSIYLEPTFNVPSSELYETFLDKQRILAWTRSAQFFNSGPKLETKEKFELFGGNVISELVSCEKDKKLVFHWKLKDWSAPFNSTIEMTFHESQEFHETKLQVKWTGIPVGEEDRVRANFEEYYVRSIKLTFGFGAVL", "length": 350 }, "evidence": [ { "id": "E1BSW0", "url": "https://omabrowser.org/oma/group/E1BSW0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8N9S3-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 2", "gene_name": "Ahsa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKWGQGDPRWIVEEREDGTNVNNWHWTERDATIWSKGKLRELLVGIAMENEAGRCEISELKQVEGEASCNSRKGKLIFFYEWNIKLAWKGTVKESGAKHKGLIEIPSLSEENEINDTEVNVSKKKGDGEILKDLMRTTGTAKVREALGEYLKALKTEFTTGMILPTKAVATQELTLQRKLNENKLQASPVALGVRIPTVALHLTELFDTTVEQLYSIFTVKELVQKFSKSPAVLEAERGGKFQMFDGNISGEYVELVTNRKIIMKWRCRNWPEEHYATVELNFVPAPGQTELQLDCKGVPVCKEENMKFCWQKQHFEEIKGLLELTAQNA", "length": 331 }, "evidence": [ { "id": "E1BSW0", "url": "https://omabrowser.org/oma/group/E1BSW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LHL7-1", "protein_name": "Aha1 domain-containing protein", "gene_name": "MEC18.18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKFGEGDKRWIVEDRPDGTNVHNWHWSETNCLEWSRNFFTKQFSGVDILSGEGNLFIKVSKIEKVEGEAYVNVRKGKIIPGYELNVSLSWEGEAKDSDGKTLLKADGLVDMPYISDENADEDPEIRFSVKDEGPIGRTLKEAMVKKGKEIILEKVRVYVEAMARGGPCRDELESKKVAPKSVAAGSATVAVEKSGAAPVVSAAAVESKVVKEKKKAKTKEGFKTITMTEKFNCRARDLYEILMDENRWKGFTQSNAKISKDVNGPISVFDGSVTGMNLELEEGKLIVQKWRFGSWPDGLDSTVKIVFEEPQPGVTIVNLTHTDVPEEDRYGNATVVENTERGWRDLIFHRIRAVFGFGI", "length": 360 }, "evidence": [ { "id": "E1BSW0", "url": "https://omabrowser.org/oma/group/E1BSW0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V9Q4-1", "protein_name": "Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein", "gene_name": "Dmel\\CG1416", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKWGEGDPRWIVEERPDATNVNNWHWTEKNATPWSKDRLHQLFQDFKIGQSDIECAVDSVDKCSGEATVNNRKGKLIFFYEWELVLKWSGKLLKNSKLIHKGKLTIPNLSEENELADVEITVTIDESNDESETLKQFMYNVGRDRVRQQLASYIRELKEEYSKNLILPKKGDEAGAGNTVANFKDANNTRNAAQNIALNSSVAAPRLKNSGIGCKLDVRTLSMTEEFHCSANDLYNALTKPEMVTAFTRAPAKVDAVRGGEFILYGGNVLGKFEELVPEKKIQQSWRLKNWTSGHYSNVVIELEETSSSTMMSLKQTGIPASEFDAMKTNWYRYYWHSIKQTFGFGTSISDAL", "length": 354 }, "evidence": [ { "id": "E1BSW0", "url": "https://omabrowser.org/oma/group/E1BSW0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BSW0", "url": "https://www.uniprot.org/uniprotkb/E1BSW0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "E1BSW0", "url": "https://www.uniprot.org/uniprotkb/E1BSW0" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "E1BSW0", "url": "https://www.uniprot.org/uniprotkb/E1BSW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1BSW0", "url": "https://www.uniprot.org/uniprotkb/E1BSW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSW0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 336, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSW0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSW0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSW0" }, { "id": "SM01000", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01000" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Activator of Hsp90 ATPase AHSA1-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 163, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BSZ9-1", "uniprot_ac": "E1BSZ9", "uniprot_id": "E1BSZ9_CHICK", "mass": { "chemical_mass": 38371.0, "monoisotopic_mass": 38371.0 }, "refseq": { "ac": "XP_001233045", "name": "magnesium transporter NIPA2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233045" }, "gene_names": [ { "name": "LOC769755", "type": "recommended", "evidence": [ { "id": "E1BSZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9" } ] }, { "name": "LOC769755", "type": "synonym", "evidence": [ { "id": "XP_001233045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233045" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "E1BSZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9/entry#names_and_taxonomy" } ] }, { "name": "magnesium transporter NIPA2", "type": "synonym", "evidence": [ { "id": "XP_001233045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233045" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001233045.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233045" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BSZ9", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC769755", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9", "locus": {} } ], "crossref": [ { "id": "E1BSZ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BSZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004975", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769755", "url": "https://www.ncbi.nlm.nih.gov/gene/769755", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008521", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008521", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769755", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769755", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEWLWWA", "url": "https://omabrowser.org/oma/group/QEWLWWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BSZ9", "url": "https://www.orthodb.org/?gene=E1BSZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001233045", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BSZ9", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSZ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPAGGRSGFYVGLGLALASSAFIGGSFILKKKGLLRLCGRGRPRAGHGGHAYLREWLWWAGLLCMGIGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSTFLNEQLNVHGKIGCVLSILGSTVMVIHAPQEEEVSSLESMAEKLKDPGFIVFAVCVLVSSLLLIFVAGPRYGRSNVLVYVLVCSAIGSLSVSCVKGLGIALKELFAGKPVLKEPLGWVLLVCLVICISVQINYLNKALDIFNTSVVTPIYYVLFTTAVMTCSAILFKEWQHMVLDNIIGTISGFLTIVSGIFLLHAFRDVPFSPDLLPLFLQQGRADLHTAWRSTDRHQSCQHQPLLPSEDKSSQSTEEEEGESV", "length": 357, "header": "tr|E1BSZ9-1|E1BSZ9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC769755 PE=3 SV=2 CANONICAL=E1BSZ9-1" }, "isoforms": [ { "isoform_ac": "E1BSZ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9/entry#E1BSZ9-1", "sequence": { "sequence": "MGPAGGRSGFYVGLGLALASSAFIGGSFILKKKGLLRLCGRGRPRAGHGGHAYLREWLWWAGLLCMGIGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSTFLNEQLNVHGKIGCVLSILGSTVMVIHAPQEEEVSSLESMAEKLKDPGFIVFAVCVLVSSLLLIFVAGPRYGRSNVLVYVLVCSAIGSLSVSCVKGLGIALKELFAGKPVLKEPLGWVLLVCLVICISVQINYLNKALDIFNTSVVTPIYYVLFTTAVMTCSAILFKEWQHMVLDNIIGTISGFLTIVSGIFLLHAFRDVPFSPDLLPLFLQQGRADLHTAWRSTDRHQSCQHQPLLPSEDKSSQSTEEEEGESV", "length": 357, "header": "tr|E1BSZ9-1|E1BSZ9_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC769755 PE=3 SV=2 CANONICAL=E1BSZ9-1" }, "locus": { "chromosome": "4", "start_pos": 2001357, "end_pos": 1998802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038531.1", "url": "https://www.ensembl.org/id/ENSGALT00010038531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022296.1", "url": "https://www.ensembl.org/id/ENSGALP00010022296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769755", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769755", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "magnesium ion transport", "id": "GO:0015693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015693", "evidence": [ { "database": "UniProtKB", "id": "E1BSZ9", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BSZ9", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "magnesium ion transmembrane transporter activity", "id": "GO:0015095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015095", "evidence": [ { "database": "UniProtKB", "id": "E1BSZ9", "url": "https://www.uniprot.org/uniprotkb/E1BSZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BSZ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 357, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BSZ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BSZ9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BT05-1", "uniprot_ac": "E1BT05", "uniprot_id": "E1BT05_CHICK", "mass": { "chemical_mass": 121500.0, "monoisotopic_mass": 121500.0 }, "refseq": { "ac": "NP_001155865", "name": "SUMO-specific isopeptidase USPL1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155865" }, "gene_names": [ { "name": "USPL1", "type": "recommended", "evidence": [ { "id": "E1BT05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ] }, { "name": "USPL1", "type": "synonym", "evidence": [ { "id": "NP_001155865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155865" } ] } ], "protein_names": [ { "name": "SUMO-specific isopeptidase USPL1", "type": "synonym", "evidence": [ { "id": "NP_001155865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155865" } ] }, { "name": "Ubiquitin specific peptidase like 1", "type": "synonym", "evidence": [ { "id": "E1BT05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT05/entry#names_and_taxonomy" } ] }, { "name": "retinovin", "type": "synonym", "evidence": [ { "id": "NP_001155865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155865" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000027.1. On Jun 21, 2009 this sequence version replaced XP_001233144.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001155865", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155865" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USPL1", "url": "https://www.uniprot.org/uniprotkb/E1BT05", "locus": { "chromosome": "1", "start_pos": 174934378, "end_pos": 174950888, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006988", "url": "https://www.ensembl.org/id/ENSGALG00010006988" } ] } } ], "crossref": [ { "id": "E1BT05", "url": "https://alphafold.ebi.ac.uk/entry/E1BT05", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017079", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017079", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "395436", "url": "https://www.ncbi.nlm.nih.gov/gene/395436", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395436", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395436", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NANALCW", "url": "https://omabrowser.org/oma/group/NANALCW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMG3", "url": "https://www.orthodb.org/?gene=A0A8V0XMG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BT05", "url": "https://www.orthodb.org/?gene=E1BT05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15294:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15294:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15509", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15509", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001155865", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155865", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT05-1", "url": "https://www.uniprot.org/uniprotkb/E1BT05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTQKTTNGLRVIGQGTGIGKSTLHMVGYLGKSHAPVEKTSPDYCPVCKEKGQVQVLRTYRINFQESIYLCENPQCIYPLGYKPFNSIIISADSENLQVPSYDKKRKLCDISDLSPIESNPKQARTNNVVNVEQAINTDPVVKSCGDSLCIPQSRVCDVLENGQQKSNSEESINQKVDFETTSNTNGHQESPPKNFSSRTQLLPNSTHSSTASEVLLRDNNCSTNNTELCLQWRNKYNLCWLDCVLSALVHLEALKFALVEEDDEKCLLQRLLTKYSQATVLLNTCKRGKVKDILPKAELLLNEIRNQIFIQLQPQLKCELGKEESPVFALPLLLKQDQHAEKLFSHSFSWKFECMCCGYKYLDRCRKTLTTFTNIIPDWHPLNAVHVAPCNNCSDRSQRRQMILEKVPSILMFHFQEGLPHNKLKSYSFQLEEDVYQITSVIQYAVHKKHFITWSLNPDGTWLECDDLKGPYCRRHKRFEVPPTEIHIVIWEKKASRLPEEQDSQYQSKNIEDSSTNNVQLKSTVLHCGFDDAVDNMLAEDHQEDTVRIPDKKQQRVAEGESSARCGLENLARDGLVTQILEETPLDSEGKSMLSRKMVENNLVVETGSQEKQESAFSPNTPCTGEFIATDLAMNDKDMLSENSSMCLSLQELNPASITSSVPKKHDPNPSDSSLAQSTGDRANLINGEHGLSSGQQINCELPPVENIVQKSPDLTGASKTAVHSQVASSSVDNNSFQPSDKDQKRGFVGSWVKKLLSKNTSFLPSSASLPKNERSCKTPSVQKLSDTWLPVKGASNFGGFQGRGERKSSQTLTSVLPRSNNAQCLSKFQGFSQGTCLPRSHSAKEGPTWNKSGNTQGGSGKTTQVHPPSCNSVKAEESDSDKTRKLRLKLLKKLNAKKKKLASLDRLAVEQAKRGKPVARDVSAPSQTESHNDSELLQSFLRELQYHIDAADNSSEFSVNSGCTSHNSNDEILAELLSPASTVASSEVPKSEDECMYMEMVNSSSAAPAEPAEKTSVSHAAVTSEDRSYYGPVKDSNYERTVSKSSVKKTGFESPTREDILEDLFSISAPTTMAGDMDVPHFDETLFETW", "length": 1092, "header": "tr|E1BT05-1|E1BT05_CHICK Isoform 1 of Ubiquitin specific peptidase like 1 OS=Gallus gallus OX=9031 GN=USPL1 PE=4 SV=2 CANONICAL=E1BT05-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XMG3-1", "url": "https://www.uniprot.org/uniprotkb/E1BT05/entry#A0A8V0XMG3-1", "sequence": { "sequence": "MLRNSSRIHFHGSLNACLCHNMQPFPFVNCKYLLCRKTLTTFTNIIPDWHPLNAVHVAPCNNCSDRSQRRQMILEKVPSILMFHFQEGLPHNKLKSYSFQLEEDVYQITSVIQYAVHKKHFITWSLNPDGTWLECDDLKGPYCRRHKRFEVPPTEIHIVIWEKKASRLPEEQDSQYQSKNIEDSSTNNVQLKSTVLHCGFDDAVDNMLAEDHQEDTVRIPDKKQQRVAEGESSARCGLENLARDGLVTQILEETPLDSEGKSMLSRKMVENNLVVETGSQEKQESAFSPNTPCTGEFIATDLAMNDKDMLSENSSMCLSLQELNPASITSSVPKKHDPNPSDSSLAQSTGDRANLINGEHGLSSGQQINCELPPVENIVQKSPDLTGASKTAVHSQVASSSVDNNSFQPSDKDQKRGFVGSWVKKLLSKNTSFLPSSASLPKNERSCKTPSVQKLSDTWLPVKGASNFGGFQGRGERKSSQTLTSVLPRSNNAQCLSKFQGFSQGTCLPRSHSAKEGPTWNKSGNTQGGSGKTTQVHPPSCNSVKAEESDSDKTRKLRLKLLKKLNAKKKKLASLDRLAVEQAKRGKPVARDVSAPSQTESHNDSELLQSFLRELQYHIDAADNSSEFSVNSGCTSHNSNDEILAELLSPASTVASSEVPKSEDECMYMEMVNSSSAAPAEPAEKTSVSHAAVTSEDRSYYGPVKDSNYERTVSKSSVKKTGFESPTREDILEDLFSISAPTTMAGDMDVPHFDETLFETW", "length": 761, "header": "tr|A0A8V0XMG3-1|A0A8V0XMG3_CHICK Computationally mapped isoform of Ubiquitin specific peptidase like 1 OS=Gallus gallus OX=9031 GN=USPL1 PE=4 SV=1 CANONICAL=E1BT05-1" }, "locus": { "chromosome": "1", "start_pos": 174941043, "end_pos": 174935886, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016596.1", "url": "https://www.ensembl.org/id/ENSGALT00010016596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009390.1", "url": "https://www.ensembl.org/id/ENSGALP00010009390.1" } ] } }, { "isoform_ac": "E1BT05-1", "url": "https://www.uniprot.org/uniprotkb/E1BT05/entry#E1BT05-1", "sequence": { "sequence": "MDTQKTTNGLRVIGQGTGIGKSTLHMVGYLGKSHAPVEKTSPDYCPVCKEKGQVQVLRTYRINFQESIYLCENPQCIYPLGYKPFNSIIISADSENLQVPSYDKKRKLCDISDLSPIESNPKQARTNNVVNVEQAINTDPVVKSCGDSLCIPQSRVCDVLENGQQKSNSEESINQKVDFETTSNTNGHQESPPKNFSSRTQLLPNSTHSSTASEVLLRDNNCSTNNTELCLQWRNKYNLCWLDCVLSALVHLEALKFALVEEDDEKCLLQRLLTKYSQATVLLNTCKRGKVKDILPKAELLLNEIRNQIFIQLQPQLKCELGKEESPVFALPLLLKQDQHAEKLFSHSFSWKFECMCCGYKYLDRCRKTLTTFTNIIPDWHPLNAVHVAPCNNCSDRSQRRQMILEKVPSILMFHFQEGLPHNKLKSYSFQLEEDVYQITSVIQYAVHKKHFITWSLNPDGTWLECDDLKGPYCRRHKRFEVPPTEIHIVIWEKKASRLPEEQDSQYQSKNIEDSSTNNVQLKSTVLHCGFDDAVDNMLAEDHQEDTVRIPDKKQQRVAEGESSARCGLENLARDGLVTQILEETPLDSEGKSMLSRKMVENNLVVETGSQEKQESAFSPNTPCTGEFIATDLAMNDKDMLSENSSMCLSLQELNPASITSSVPKKHDPNPSDSSLAQSTGDRANLINGEHGLSSGQQINCELPPVENIVQKSPDLTGASKTAVHSQVASSSVDNNSFQPSDKDQKRGFVGSWVKKLLSKNTSFLPSSASLPKNERSCKTPSVQKLSDTWLPVKGASNFGGFQGRGERKSSQTLTSVLPRSNNAQCLSKFQGFSQGTCLPRSHSAKEGPTWNKSGNTQGGSGKTTQVHPPSCNSVKAEESDSDKTRKLRLKLLKKLNAKKKKLASLDRLAVEQAKRGKPVARDVSAPSQTESHNDSELLQSFLRELQYHIDAADNSSEFSVNSGCTSHNSNDEILAELLSPASTVASSEVPKSEDECMYMEMVNSSSAAPAEPAEKTSVSHAAVTSEDRSYYGPVKDSNYERTVSKSSVKKTGFESPTREDILEDLFSISAPTTMAGDMDVPHFDETLFETW", "length": 1092, "header": "tr|E1BT05-1|E1BT05_CHICK Isoform 1 of Ubiquitin specific peptidase like 1 OS=Gallus gallus OX=9031 GN=USPL1 PE=4 SV=2 CANONICAL=E1BT05-1" }, "locus": { "chromosome": "1", "start_pos": 174946349, "end_pos": 174935886, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016597.1", "url": "https://www.ensembl.org/id/ENSGALT00010016597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009391.1", "url": "https://www.ensembl.org/id/ENSGALP00010009391.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395436", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395436", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LEA5-1", "protein_name": "Ubiquitin specific peptidase like 1", "gene_name": "Uspl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKFRYCTDYTWRKGNEDNLFLDKLKFENHPGVLYINQCLEDLESLLLNYASAKVPADGYCPTCRAKGKLNTLKTYRISFQESIFLCEDLQCIYPLGSESLTNLISPDSEDCHTPNKPQKRKRLEDNCKNSSLPVHSKKTRGHLVTDSDQIVNGECNGEVCGDFSASFPGDSAHQDPARTAASVGQNGTLEANDNVVMATTEDPAAVGVTPELEMPSESRCLSLCQPLCVQWRNTQALCWLDCILSALVHLEVLRDAVLEVCSREECVFGKLFETYHQADKLLYTHHLHGVTGEDCKKMTTEIFTEIDTSLNKIRDEIFAKLQPKLRCTLGDMESPVFALPVLLKLEPHVENLFTYSFSWNFECSHCGHQYQNRCVKSLVTFTNVVPEWHPLNAAHFGPCNSCNSKSQIRKMVLERASPIIMLHFVEGLPRKDLQHYAFHFEGSLYQVTSVIQYRAKNHFITWTVDADGSWLECDDLKGPCAKRHEACEVPASETHIVIWERKSQVPVEGAACLPHMKLHVQSVSGEEQPSSLAGTATSEPSVAHPTPMAVAPQILPATQAVAHGDSVLSGTGGLLDSVSPSALEETIQETASVSQIDSKDCLLEDKPVVGSAGPVRTLTFQPQDSLGSSLVLNLCEGMLVAPCVDSRFPSQAVSTGLQAVPSQAGDTVVPKPVTDAPVPVLVQELKSMATEDSQTQLLPLKTDRLNPGQPPGKTQASNLRKRENAASSKPVAARSAQNQPRKDEQKKAFVGSWVKGLLSRGGAFMPPCVSAQSRAVTDLQPSVKGANNFDGFKTKSINRRSKRMSRKAKHVEEASPGSSPPLSGSTAALPQAAGNASSAQLKEQEGSRSAPLSHRPPSDESAMSPAGRAEAAEDQVHKLRLRLLKKLKAKKKKLAALMSSPRREPSVSDHSEPASHCGSPNDCDAVEDLLRELQYQIDLADNKSGCTSAPDGTSCNSQSHEEILAELLSPTALSEPSESGEPELRYLEMGDNSTPTPAPSEFSAVSQNTCLNQEHNYCSPEKSQCEVDLHSVIDSACVRALNLGSPMKTDIFDDFFPTSALNSLTNDTLDIPHFDDSLFENC", "length": 1083 }, "evidence": [ { "id": "E1BT05", "url": "https://omabrowser.org/oma/group/E1BT05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BB54-1", "protein_name": "Ubiquitin specific peptidase like 1", "gene_name": "USPL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTDSPKSGNGLPMVGPGPDIGNSSLHMVGYLGKNYDSVKVLSDGYCPACRAKGKLKALKTYRISFQESVSLCEDLQCIYPLGSKSLNNLFSPGLEDCHTPNKSQKRKILETNCEDSPLLAGSKKTKNHRGIDSEQVLNSNHNGGEYDGTSPDLPGSLYSGQQNPVRTAGCWEQNEALEADTVDMASEEDAPMVDVSGTEGTRPQNERCTSELEKPLESKHTSLCQTSCVQWKNAHALCWLDCILSALVHLEGLKSTVTDLQSKEESVFGRLFTRYSEANKLLHTSQLDGVKDGDCKKLPSEIFAKIETCLNEVRDEIFIRLQPQLRCTLGDMESPVFAFPLLLKIEPHIEQLFTYSFSWNFECSHCGHKYQNRCMKNLVTFTNVIPEWHPLKAAHFGPCNNCNNKSQIRKMVLEKVSLVFMLHFVEGLPHNDLQRYSFHSEGCLYQVTSVIQYQANNHFVTWILDADGSWLECDDLKGLCSERHETFQVPASEIHIVIWERKTSQMTDKAPACHPLKKTSDQYAFGDEKQVFPAACSAGEAASAEPSSGTHPTDVSMVPNTLSQDEAVAPGRHSLPNLKGSVDSGILPLTLEEVQSNSEGFLLEHKPVAENAGVVEANTLQSEEPLIALLVAPFEDKLTHNQPDLSFSSQLLTMPSVQVSTEDTAVTQPVNDTQAGGLIQQVKPVDTEGAVALERNASLKQFLVAETEKLNPEQHVTSQVSDWKEKETTAFSQTVTAKPLQNPPLKENQKKPFVGSWVKGLLSKGVSFMPSCVSAHNRNTVTDLQPSVKGASNFGGFQTKGSRQKASQASRKAHRRAAKPPLLSNSPPSHQSPTSTASPPRADGTGDSEVWKRCESASCGAYLNHNSHGNENGVSSPNHGDTIEGQIHKLRLKLLKKLKAKKKKLASLMSSPQNGTLPSEPSEQVSHCGSPNDSESIEGLLQELQRQIDIADNKSGCATVPGVSPYGGQTHEEILAELLSPATVVSTELSENGEADFRYLEMGDSHIPAPVPNELNSIAHNTHLRQEHNYCSPKKNQSELQPDSLTNNAFIRTLNLESPMKTDIFDEFFSASALNSLANDTLDLPHFDEYLFENC", "length": 1095 }, "evidence": [ { "id": "E1BT05", "url": "https://omabrowser.org/oma/group/E1BT05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GWG1-1", "protein_name": "SUMO-specific isopeptidase USPL1 isoform X1", "gene_name": "Uspl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESLKIGNGLPRVGPGTDIGISSLPKLGYLGKNYDSAKVTTDGQCPACRAKGKLNNLKTYQINFQESIFLCEDLQCIYPLGSESLTNLISPDSGDCHTQNKPQKRKRLETNAKSSPLPVHSKKTRNHVVTDGEQNLNAKYNGKVCGDTSSNLPDNTSHQNHVRAVASSEQNETLEVDTVDTLDVDTVDVSTKEDPATVSVFGVLTQSQGSELEMPSESRCLPFCQTLCVQWRNSQALCWLDCILSALVHLEALRNTVMEVCSREECVFGRLFETYHQADKLLYTHHLHGVTGEDCKQLRSEILAEIETCLNGVRGEIFTKLQPKLRCTLGEMESPVFAFPALLKLEPHVEKLFTYSFSWNFECSNCGHQYQNRCLKSLVTFTNVVPEWHPLNAAHFGPCNSCNSKSQIRKMVLERASPIFMLHFVEGLPRKDLQHYAFHFEDSLYQVTCVIQYQANNHFITWIVEADGSWLECDDLKGSFAKRHVTCEVPASEIHIVVWERKSQVPTEEATCLPCTKPSAQPASGEEQPASPTLCSVGGAATSEPSVAHLTHMPVAPQTLPEVQAVAHGDSVLSGTKGLVEAASVFQVDFKDCLLEDKPVAESAELVRALSLQPQDSLMTSLLSNPYEGKLVTPPVVSTDPEAVPSQAGDTVIPNSVTDAPVPVPVQELKSMVAEKDTQIQLLPLSAERLKPAQPAKSQASNVRKRETAASSKTVMASSLQTQPQKDDQKKAFVGSWVKGLLSRGGSFMPPCVLAQNRAVTDLQPSVKGANNFDGFKTKNVNRKAKRMSRKASKHVDEPTAGSCSPPSGSTATLPHAGGNATSILLKGQESSRATPLSNNLHSSESVISPASCGDAAEDQVHKLRLKLLKKLKAKKKKLAALMSSPNRGTSVSDHSEPVSHCGSPNDCESIEDLLNELQYQIDLADNKSGCTTAPDGTSCNSQSHEEILAELLSPPALSEPSASVESELRYLEVGDSTPAPTEFNAVSQSICLGQDHNYCSPKKNQCEAEVQSLTDSACIRALNLGSPMKTDIFDDFFPTSALNSLANDTLDIPHFDEYLFENC", "length": 1064 }, "evidence": [ { "id": "E1BT05", "url": "https://omabrowser.org/oma/group/E1BT05/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LMI0-1", "protein_name": "Ubiquitin specific peptidase like 1", "gene_name": "USPL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMDSPKIGNGLPVIGPGPDIGISPLHMVGYLGKNCDSAQVPSDGYCPACRTKGKLKALKSYRISFQESVFLCEDLQCIYPLGSKSLNNVISPDLEDCHTPNKPQKRKILETNSSDSPLLANSKKTKNHIGIDGEQVLNSKHNEEERDETSSDVPGLLPDCQQNPVRTADSLEQNEILEADIDVATEEDFTTVDASATGGSSPQNEGCTSELEVPLESKRTSFCQTSCVQWKNTHALCWLDCILSALVHLEGLKNTVTDLCSEEESVFRRLFTRYNQANELLLTSQSDGVKGGECKKLHSEIFPKIETCLNEVRDEIFIRLQPQLRCTLGDMESPVFAFPLLLKIEPDIERLFTYSFSWNFECSHCGHKYQNRCMKNLVTFTNVIPEWHPLNAAHFGPCNNCNNKLQIRKMVLEKVSPMFMLHFVEGLPHNDLQRYAFHAEGCLYQISSVIQYQANNHFITWILDADGCWLECDDLKGLCSERREKFKVPASEIHIVIWERKASQMTDKASASQPLKKPSDQHAFGDEKPASPALCHLGDAASAEMALGTYPTNVSVAPNTLSQDDAIAIGHHLLSSPKGLADSMLPLTLQEIQVNSEGFLLENKAVAENAGVVKTDTLQSQESLIASLVSAPCKDKLTQDQRVDLSFSSQLVNMKMPSIQPNTEDTVVCKPVNGIHAADPIQEVTSVEIEGTVALEKDAPSKQFLSPKTEKIKPEQHVTSQVSDLKEKETAAFSQTVTAKSLQNPALKENQKKPFVGSWVKGLLSKGASFMPPCVSAHNRNAITDLQPSVKGASNFGGFKTKGSKQKANRASRKAPRCAGKGPPVSTPPPSQPSAVSPASLHGNGHVDLLKKCENASYGSHLNHSSHGSENGVSSANHRDSAEDQVHKLRLKLLKKLKAKKKKLAALMSSPQNGALAGENSEPVSHCGSPNDCESIEDLLKELQYQIDIADSKSGCTTVPSVSPYSGQTHEEILAELLSPTTAVATELSEHGEADFRYLEMGDNHIPAPEPNELNSIPQNTHLRQDHNYCSPTKKSHCEVQPDSLTNNACLRTLNSESPMKTDIFDEFFSPSALNSLANDTLDLPHFDEYLFENC", "length": 1095 }, "evidence": [ { "id": "E1BT05", "url": "https://omabrowser.org/oma/group/E1BT05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ULM6-1", "protein_name": "SUMO-specific isopeptidase USPL1", "gene_name": "Uspl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDDSLKIGNGLPLVGPGTDVGISSLPMLGYLGKNYASAKVTTDGHCPACRAKGKLSALKPYRISFQESVFLCEDLQCIYPLGSESLTNLISPDSEDCPTPSKPQKRKRLETNCRNSPLPVHSKKTRSHIVTDSEPIVNGKYNGEVCDDFSASFPDTSAHQDPASTAASVEQSEALEADDVVVAATEDPATVSVTSELEMPAKSRCLPLCQTLCVQWKNTQALCWLDCILSALVHLEVLRKTVLEACSREECVFGRLFEMYHQADELLHTHHLHGVTGEDCKKLTSEIFTEIDTCLNKVRDEIFAKLQPKLRCTLGDMESPVFALPVLLKLEPHVESLFTYSFSWNFECSHCGHQYQNRCVKSLVTFTNIVPEWHPLNAAHFGPCNSCNSKSQIRKMVLERASPILMLHFVEGLPRRDLQHYAFHFEGSLYQVTSVIQYQANNHFITWFLDADGSWLECDDLKGPCAKRHVTCEVPASETHIVIWERKSQVPIEEAACLPCMKPNVQPVSGEEQPTCPALCSLAGTATSEPSVAHPTSMAGAPQTLPEIQAVAHGDSVLSGAKGMVDSILPSALEETIQETASVSQVDSKDCLLEDKPVAGSAALVRVLAFQPQDSPGSSGSSLVSSLCEGKLVAPCVDSSFPSQAVSTDLQAVLSQAGDTVVPNPVTDAPVPVLVQELKSLATEKDSQTQLLPLKTEKLDPEQPGKSQASNLRKRETTASSKTVAARSAQNQPRKEDQKRAFVGSWVKGLLSRGGAFMPTCVLSQSRAVSDLQPSVKGASNFDGFKTKSISRRSKRMSRKAKHMEELSPRNSSPPLSWTAALTQAAENATSALLREQEGSRPAPLRHRSPGNESAISPASRGDAAEDQVHKLRLKLLKKLKAKKKKLAALISSPHREPSLSDHSEPASHCGTPASDQSEPVSHCGSPNDCESIEDLLKELQHQIDLADSKSGCTSAPDATSNNSQSHEEILAELLSPTAMSEPSESGELELRYLEMGDSTPAQAPSEFSVVSLNTCLKQDHDYCSPEKGQREVDLHSVMDSACIRTLNLGSPMKTDIFDDFFSTSALNSLTNDTLDIPHFDDSLFENC", "length": 1089 }, "evidence": [ { "id": "E1BT05", "url": "https://omabrowser.org/oma/group/E1BT05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5W0Q7-1", "protein_name": "SUMO-specific isopeptidase USPL1", "gene_name": "USPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMDSPKIGNGLPVIGPGTDIGISSLHMVGYLGKNFDSAKVPSDEYCPACREKGKLKALKTYRISFQESIFLCEDLQCIYPLGSKSLNNLISPDLEECHTPHKPQKRKSLESSYKDSLLLANSKKTRNYIAIDGGKVLNSKHNGEVYDETSSNLPDSSGQQNPIRTADSLERNEILEADTVDMATTKDPATVDVSGTGRPSPQNEGCTSKLEMPLESKCTSFPQALCVQWKNAYALCWLDCILSALVHSEELKNTVTGLCSKEESIFWRLLTKYNQANTLLYTSQLSGVKDGDCKKLTSEIFAEIETCLNEVRDEIFISLQPQLRCTLGDMESPVFAFPLLLKLETHIEKLFLYSFSWDFECSQCGHQYQNRHMKSLVTFTNVIPEWHPLNAAHFGPCNNCNSKSQIRKMVLEKVSPIFMLHFVEGLPQNDLQHYAFHFEGCLYQITSVIQYRANNHFITWILDADGSWLECDDLKGPCSERHKKFEVPASEIHIVIWERKISQVTDKEAACLPLKKTNDQHALSNEKPVSLTSCSVGDAASAETASVTHPKDISVAPRTLSQDTAVTHGDHLLSGPKGLVDNILPLTLEETIQKTASVSQLNSEAFLLENKPVAENTGILKTNTLLSQESLMASSVSAPCNEKLIQDQFVDISFPSQVVNTNMQSVQLNTEDTVNTKSVNNTDATGLIQGVKSVEIEKDAQLKQFLTPKTEQLKPERVTSQVSNLKKKETTADSQTTTSKSLQNQSLKENQKKPFVGSWVKGLISRGASFMPLCVSAHNRNTITDLQPSVKGVNNFGGFKTKGINQKASHVSKKARKSASKPPPISKPPAGPPSSNGTAAHPHAHAASEVLEKSGSTSCGAQLNHSSYGNGISSANHEDLVEGQIHKLRLKLRKKLKAEKKKLAALMSSPQSRTVRSENLEQVPQDGSPNDCESIEDLLNELPYPIDIASESACTTVPGVSLYSSQTHEEILAELLSPTPVSTELSENGEGDFRYLGMGDSHIPPPVPSEFNDVSQNTHLRQDHNYCSPTKKNPCEVQPDSLTNNACVRTLNLESPMKTDIFDEFFSSSALNALANDTLDLPHFDEYLFENY", "length": 1092 }, "evidence": [ { "id": "E1BT05", "url": "https://omabrowser.org/oma/group/E1BT05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "deSUMOylase activity", "id": "GO:0016929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016929", "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "pmid": "" }, { "name": "SUMO binding", "id": "GO:0032183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032183", "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "snRNA transcription", "id": "GO:0009301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009301", "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "pmid": "" }, { "name": "Cajal body organization", "id": "GO:0030576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030576", "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "pmid": "" }, { "name": "protein desumoylation", "id": "GO:0016926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016926", "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "E1BT05", "url": "https://www.uniprot.org/uniprotkb/E1BT05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" }, { "start_pos": 955, "end_pos": 957, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BT05-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1092, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BT05-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BT05" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1004, "end_pos": 1006 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 644, "end_pos": 646 }, { "start_pos": 735, "end_pos": 737 }, { "start_pos": 761, "end_pos": 763 }, { "start_pos": 852, "end_pos": 854 }, { "start_pos": 934, "end_pos": 936 }, { "start_pos": 955, "end_pos": 957 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BT36-1", "uniprot_ac": "E1BT36", "uniprot_id": "E1BT36_CHICK", "mass": { "chemical_mass": 54114.0, "monoisotopic_mass": 54114.0 }, "refseq": { "ac": "XP_004940281", "name": "transmembrane protein 200A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940281" }, "gene_names": [ { "name": "TMEM200A", "type": "recommended", "evidence": [ { "id": "E1BT36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT36" } ] }, { "name": "TMEM200A", "type": "synonym", "evidence": [ { "id": "XP_004940281", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940281" } ] } ], "protein_names": [ { "name": "Transmembrane protein 200A", "type": "synonym", "evidence": [ { "id": "E1BT36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT36/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 200A", "type": "synonym", "evidence": [ { "id": "XP_004940281", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940281" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940281" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BT36", "url": "https://www.uniprot.org/uniprotkb/E1BT36" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM200A", "url": "https://www.uniprot.org/uniprotkb/E1BT36", "locus": { "chromosome": "3", "start_pos": 57425668, "end_pos": 57484657, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005248", "url": "https://www.ensembl.org/id/ENSGALG00010005248" } ] } } ], "crossref": [ { "id": "ENSGALG00000002282", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002282", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427076", "url": "https://www.ncbi.nlm.nih.gov/gene/427076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427076", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQPVSTM", "url": "https://omabrowser.org/oma/group/FQPVSTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BT36", "url": "https://www.orthodb.org/?gene=E1BT36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31815:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31815:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940281", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BT36", "url": "https://www.uniprot.org/uniprotkb/E1BT36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT36-1", "url": "https://www.uniprot.org/uniprotkb/E1BT36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHVNLAAAPASEEKKPVRRRPRADVVIVRGKIRLYSPSGFFLVLGVLIAFLGIAMAILGYWPQKEQLLASEDSVSVNETQVLRNQGSILLRFFEQHVHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKQLSGAFAGLLGEGELRHSGSSCASRLAANTVAPFSGFKSSFRMDSSAEEDEITLNEDRTTASLLPPLLTEQSGSVFGLYPHSSKASDDKNTSSIKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDSEITRSRSRNISMDSLAIPLTDTDESCKPAMLPRHNSFVDTQHDQFKSSMTLGPSTGKLLSPGAARKQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRSNSKGYMKLENKEDPMDRLLVPQAVVKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 489, "header": "tr|E1BT36-1|E1BT36_CHICK Isoform 1 of Transmembrane protein 200A OS=Gallus gallus OX=9031 GN=TMEM200A PE=3 SV=1 CANONICAL=E1BT36-1" }, "isoforms": [ { "isoform_ac": "E1BT36-1", "url": "https://www.uniprot.org/uniprotkb/E1BT36/entry#E1BT36-1", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHVNLAAAPASEEKKPVRRRPRADVVIVRGKIRLYSPSGFFLVLGVLIAFLGIAMAILGYWPQKEQLLASEDSVSVNETQVLRNQGSILLRFFEQHVHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKQLSGAFAGLLGEGELRHSGSSCASRLAANTVAPFSGFKSSFRMDSSAEEDEITLNEDRTTASLLPPLLTEQSGSVFGLYPHSSKASDDKNTSSIKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDSEITRSRSRNISMDSLAIPLTDTDESCKPAMLPRHNSFVDTQHDQFKSSMTLGPSTGKLLSPGAARKQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRSNSKGYMKLENKEDPMDRLLVPQAVVKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 489, "header": "tr|E1BT36-1|E1BT36_CHICK Isoform 1 of Transmembrane protein 200A OS=Gallus gallus OX=9031 GN=TMEM200A PE=3 SV=1 CANONICAL=E1BT36-1" }, "locus": { "chromosome": "3", "start_pos": 57435056, "end_pos": 57433590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012428.1", "url": "https://www.ensembl.org/id/ENSGALT00010012428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010006992.1", "url": "https://www.ensembl.org/id/ENSGALP00010006992.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427076", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S3M7-1", "protein_name": "Transmembrane protein 200A", "gene_name": "TMEM200A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQHHVNLSPSPAAQEKKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIVGIAMAVLGYWPQKEHFIDAETTLSTNETEVIRNQGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKHMNGIYTGLMGETEVKQNGNSCASRLAANTIASFSGFRSSFRMDSSVEEDELVINESKSLGHLIPPLLSDNSASVCGLYPPPSKTAEDKSSGPKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADTLKSRSRNLSMDSLMLPLPNSSQPFQPVSMILPRNNSIGESLSSQYKSSVALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRSNSKGYMKLENKEDPVERLLVPQAAVKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "E1BT36", "url": "https://omabrowser.org/oma/group/E1BT36/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IP88-1", "protein_name": "Transmembrane protein 200A", "gene_name": "Tmem200a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHVNLSPAPAAQDQKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLVSIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVVRNQGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRLKEQKQANGLYAGLLGDVEVKQNGSPCASRLAATTLASFSGLRNSFRVDSSVEEDELMLSESKSLGHLMPPLLSDSAVSVFGLYPPPSKTTDDKTSSSKKCDTKSIVSSSISAFTLPVIKLNNCVIDEPGIDSITEVADNLKSRSRNLSMDSLMVPLPSSGEAFQPSSTLLPRNNSVGESLSSQYKSSVALGPGTGQLLSPGAARRQFGSNTSLHFLSSHSKSLDLERGPSTLTVQAEQRKHPSWPRLDRSNSKGYMKLENKEDPMDRLLVPQTAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "E1BT36", "url": "https://omabrowser.org/oma/group/E1BT36/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MXC0-1", "protein_name": "Transmembrane protein 200A", "gene_name": "TMEM200A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQHHDNLSPSPAAQEKKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIVGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNQGGVVVHFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQKHMNGIYTGLMGETEVKQNGNSCASRLAANTIASFSGFRSSFRMDSSVEEDELVVNESKSFGHLVPPLLSDSSASVCGLYPPPSKTTDDKTSGPKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADNLKSRSRNLSMDSLMVPLPNPSQPFQPVSLMLPRNNSVGESLSSQYKSSVALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLERGHSTLTVQAEQRKHPSWPRLDRSNSKGYVKLENKEDPMERLLVPQAAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "E1BT36", "url": "https://omabrowser.org/oma/group/E1BT36/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5RGQ8-1", "protein_name": "Transmembrane protein 200A", "gene_name": "tmem200a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIATGGVITGLAALKRQDSTRSQYHLSAQSPGPAPEKKTTKRKPRADVVVVRGKIRLYSASGFFLVLGVLILMAGIAMAVLGYWPHKDQPKAPETKMSANNTQSFGREQAGSIAQFLEQHMHSEKMKMLGPFTMGIGIFIFICANAILHENRDRETKVIHMRDMYSTVIDIHSLRIKEQKCTNGACMGPYGGDTEIRTFGLDSQFASRLAANTLMSFSGLDGDVRFSHRTSSADDDDGLMSEARGGFCLLSPTYKDRSECIFGFQDDGRWEDRRGALKKCQTRSIVSSSISAFTLPVIKLNNCVIDEPDIDSITEDLEQSRVHSRPPSMESLTVPVPDIAKAFKPPGVQLLRSNSATESASSTSSRSSLSPGSTSGRFLSPGAARKDFGSNNSIHMLSAHSKSLDLERGPTKLTVQPEQRKHPSWPRLDRSNSKGYTRLENKEDPMDRLIVPPVDVKKDYTKKEKLLMISRSHNNLSFEHDEFMSSGLKRGTSETRF", "length": 497 }, "evidence": [ { "id": "E1BT36", "url": "https://omabrowser.org/oma/group/E1BT36/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86VY9-1", "protein_name": "Transmembrane protein 200A", "gene_name": "TMEM200A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHVNLSPSPATQEKKPIRRRPRADVVVVRGKIRLYSPSGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNEGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQRQMNGMYTGLMGETEVKQNGSSCASRLAANTIASFSGFRSSFRMDSSVEEDELMLNEGKSSGHLMPPLLSDSSVSVFGLYPPPSKTTDDKTSGSKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITEDADNLKSRSRNLSMDSLVVPLPNTSESFQPVSTVLPRNNSIGESLSSQYKSSMALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWPRLDRNNSKGYMKLENKEDPMDRLLVPQVAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "E1BT36", "url": "https://omabrowser.org/oma/group/E1BT36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C817-1", "protein_name": "Transmembrane protein 200A", "gene_name": "Tmem200a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIATGGVITGLAALKRQDSARSQQHINLSPLPATQDQKPVRRRPRADVVVVRGKIRLYSPSGFFLILGVLVSIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVVRNQGGVVVRFFEQHLHSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRLKEQKQANGLYAGLLGDTEVKQNGSPCASRLAATTLASFSGMRNSFRVDSSVEEDELMLTESKSLGHLMPPLLSDSAVSVFGLYPPPAKATDDKASSSKKCDTKSIVSSSISAFTLPVIKLNNCVIDEPSIDSITEVADNLKTRSRNLSMDSLVVPLPSSGESFQPAVTLLPRNNSVGESLSSQYKSSVALGPGTGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVHAEQRKHPSWPRLDRSNSKGYMRLENKEDPMDRLLVPQTAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSNNLKRGTSETRF", "length": 491 }, "evidence": [ { "id": "E1BT36", "url": "https://omabrowser.org/oma/group/E1BT36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BT36", "url": "https://www.uniprot.org/uniprotkb/E1BT36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 467, "end_pos": 469 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BT69-1", "uniprot_ac": "E1BT69", "uniprot_id": "E1BT69_CHICK", "mass": { "chemical_mass": 32120.0, "monoisotopic_mass": 32120.0 }, "refseq": { "ac": "XP_419077", "name": "myb/SANT-like DNA-binding domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419077" }, "gene_names": [ { "name": "C2H9ORF30", "type": "recommended", "evidence": [ { "id": "E1BT69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT69" } ] }, { "name": "C2H9ORF30", "type": "synonym", "evidence": [ { "id": "XP_419077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419077" } ] } ], "protein_names": [ { "name": "Myb/SANT-like DNA-binding domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "E1BT69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT69/entry#names_and_taxonomy" } ] }, { "name": "myb/SANT-like DNA-binding domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419077" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_419077.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419077" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BT69", "url": "https://www.uniprot.org/uniprotkb/E1BT69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C2H9ORF30", "url": "https://www.uniprot.org/uniprotkb/E1BT69", "locus": {} } ], "crossref": [ { "id": "E1BT69", "url": "https://alphafold.ebi.ac.uk/entry/E1BT69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013403", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013403", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420991", "url": "https://www.ncbi.nlm.nih.gov/gene/420991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420991", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420991", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTVAKEW", "url": "https://omabrowser.org/oma/group/QTVAKEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BT69", "url": "https://www.orthodb.org/?gene=E1BT69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21632:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21632:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419077", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BT69", "url": "https://www.uniprot.org/uniprotkb/E1BT69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT69-1", "url": "https://www.uniprot.org/uniprotkb/E1BT69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNEIIKPAKYFSEVEKSVLLALVEKYRYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKSISPLINTHIIGKEKIASIMPEQIYFLQSPPEEDSEYQPDASSQESFVVSNRELCDEEKELIHFPVCEGTSQPEPSCSDVRIAADKNYRSKASQESALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTITKEWPVSSFNRPFPNSP", "length": 273, "header": "tr|E1BT69-1|E1BT69_CHICK Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=C2H9ORF30 PE=3 SV=3 CANONICAL=E1BT69-1" }, "isoforms": [ { "isoform_ac": "E1BT69-1", "url": "https://www.uniprot.org/uniprotkb/E1BT69/entry#E1BT69-1", "sequence": { "sequence": "MQNEIIKPAKYFSEVEKSVLLALVEKYRYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKSISPLINTHIIGKEKIASIMPEQIYFLQSPPEEDSEYQPDASSQESFVVSNRELCDEEKELIHFPVCEGTSQPEPSCSDVRIAADKNYRSKASQESALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTITKEWPVSSFNRPFPNSP", "length": 273, "header": "tr|E1BT69-1|E1BT69_CHICK Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 3 OS=Gallus gallus OX=9031 GN=C2H9ORF30 PE=3 SV=3 CANONICAL=E1BT69-1" }, "locus": { "chromosome": "2", "start_pos": 88708208, "end_pos": 88706105, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019745.1", "url": "https://www.ensembl.org/id/ENSGALT00010019745.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011293.1", "url": "https://www.ensembl.org/id/ENSGALP00010011293.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420991", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420991", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I3A3-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "Msantd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSNHVLGKEKISNMLPEQLYFLQSPPEEEPEYHQDAAVQESFPVSNRELCDDEKEFVHFPVCEGTSQPEPSCSAVRVTANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRVKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "E1BT69", "url": "https://omabrowser.org/oma/group/E1BT69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A3I3-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "Msantd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSTHVLDKEKIGSMLPEQLYFLQSPPEEEPEYHQDAAAQESFAVSNRELCDDEKEFVHFPVCEGTSQPEPSCSAVRITANKNYRSKTPQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "E1BT69", "url": "https://omabrowser.org/oma/group/E1BT69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0III0-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "MSANTD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHAEAAAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "E1BT69", "url": "https://omabrowser.org/oma/group/E1BT69/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96H12-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "MSANTD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "E1BT69", "url": "https://omabrowser.org/oma/group/E1BT69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CR78-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "Msantd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSSHVLDKEKISSMLPEQLYFLQSPPEEEPEYHQDAAAQESFAVSNRELCEDEKEFGPFPVCEGTSQPEPSCSAVRITANKNYRSKTPQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "E1BT69", "url": "https://omabrowser.org/oma/group/E1BT69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BT69-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 273, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BT69-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BT69" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BT69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT69" }, { "id": "PF13873", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 86, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BT99-1", "uniprot_ac": "E1BT99", "uniprot_id": "E1BT99_CHICK", "mass": { "chemical_mass": 43756.0, "monoisotopic_mass": 43756.0 }, "refseq": { "ac": "XP_015150280", "name": "G-protein coupled receptor family C group 5 member B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150280" }, "gene_names": [ { "name": "GPRC5B", "type": "recommended", "evidence": [ { "id": "E1BT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ] }, { "name": "GPRC5B", "type": "synonym", "evidence": [ { "id": "XP_015150280", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150280" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor class C group 5 member B", "type": "synonym", "evidence": [ { "id": "E1BT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT99/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor family C group 5 member B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015150280", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150280" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150280", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150280" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPRC5B", "url": "https://www.uniprot.org/uniprotkb/E1BT99", "locus": { "chromosome": "14", "start_pos": 14790397, "end_pos": 14775623, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017641", "url": "https://www.ensembl.org/id/ENSGALG00010017641" } ] } } ], "crossref": [ { "id": "E1BT99", "url": "https://alphafold.ebi.ac.uk/entry/E1BT99", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002028", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002028", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15278", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15278", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101747453", "url": "https://www.ncbi.nlm.nih.gov/gene/101747453", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GWQLVGM", "url": "https://omabrowser.org/oma/group/GWQLVGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BT99", "url": "https://www.orthodb.org/?gene=E1BT99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14511:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14511:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150280", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150280", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT99-1", "url": "https://www.uniprot.org/uniprotkb/E1BT99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTYPAIGFFVLFVISYGSSENSSTPRGCGLDLLPQYVYLCDLDAIWGIVVEAVAGAGVLTTLLLMLILLVRLPFIKEKEKKSPLGMHFLFLFGTLGLFGLTFAFIIQEDEMVCSTRRFLWGVIFALCFSCLLAQAWRLRRLVRHGKSPSGWHLAGVAICLMLVQVIIATEWLILTVVRDNKMACSYEPMDFAMALIYVMFLMVFTMGFSLFTLCGKFKKWKKNGVCLIITLFFSILIWVAWMTMYLFGNAELKRRDKWSDPTLAIALVSSGWVFVIFHAIPEVHCTILPSQQENTPNYFDTSQPRMRETAFEEDIQLPRSYMENKAFSMDEHNAALRTAGFRNGSLGSRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSYTGRHLW", "length": 387, "header": "tr|E1BT99-1|E1BT99_CHICK Isoform 1 of G protein-coupled receptor class C group 5 member B OS=Gallus gallus OX=9031 GN=GPRC5B PE=3 SV=2 CANONICAL=E1BT99-1" }, "isoforms": [ { "isoform_ac": "E1BT99-1", "url": "https://www.uniprot.org/uniprotkb/E1BT99/entry#E1BT99-1", "sequence": { "sequence": "MKTYPAIGFFVLFVISYGSSENSSTPRGCGLDLLPQYVYLCDLDAIWGIVVEAVAGAGVLTTLLLMLILLVRLPFIKEKEKKSPLGMHFLFLFGTLGLFGLTFAFIIQEDEMVCSTRRFLWGVIFALCFSCLLAQAWRLRRLVRHGKSPSGWHLAGVAICLMLVQVIIATEWLILTVVRDNKMACSYEPMDFAMALIYVMFLMVFTMGFSLFTLCGKFKKWKKNGVCLIITLFFSILIWVAWMTMYLFGNAELKRRDKWSDPTLAIALVSSGWVFVIFHAIPEVHCTILPSQQENTPNYFDTSQPRMRETAFEEDIQLPRSYMENKAFSMDEHNAALRTAGFRNGSLGSRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSYTGRHLW", "length": 387, "header": "tr|E1BT99-1|E1BT99_CHICK Isoform 1 of G protein-coupled receptor class C group 5 member B OS=Gallus gallus OX=9031 GN=GPRC5B PE=3 SV=2 CANONICAL=E1BT99-1" }, "locus": { "chromosome": "14", "start_pos": 14788206, "end_pos": 14781248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042631.1", "url": "https://www.ensembl.org/id/ENSGALT00010042631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025121.1", "url": "https://www.ensembl.org/id/ENSGALP00010025121.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K4B0-1", "protein_name": "G protein-coupled receptor, class C, group 5, member B", "gene_name": "Gprc5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VFLVSERKMRTHQVLPLPLLLVIASVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKDKERRRPVCLHFLFLLGTLGLFGLTFAFIIRMDETICSIRRFLWGVLFALCFSCLLSQAWRVRRLVRQGTSPASWQLVSLALCLMLVQVIIATEWLVLTVLRDTKPACAYEPMDFVMALIYDMVLLAITLAQSLFTLCGKFKRWKVNGAFILITTFLSVLIWVIWMTMYLFGNSLIKRADAWSDPTLAITLVASGWVFVIFHAIPEIHYTLLPPLQENPPNYFDTSQPRMRETAFEEEMHLPRAYMENKAFSMDEHNAALRSAVGFSNGSLEQRSSSLGKKPSSLGNRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHAGRHHW", "length": 410 }, "evidence": [ { "id": "E1BT99", "url": "https://omabrowser.org/oma/group/E1BT99/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A480W2U9-1", "protein_name": "G protein-coupled receptor class C group 5 member B", "gene_name": "GPRC5B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPHQVLAFLLLFVIASGASENASTSRGCGLDLLPQYVSLCDLDTIWGIVVEAVAGAGALITLLLMLILLVRLPFIKDKEKKDPVGLHFLFLLGTLGLFGLTFAFIIREDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGKSPSSWQLVGMALCLMLVQVIIAIEWLVLTVLRDAKPACAYEPMDFAMALIYDMVLLVATLGLALFTLCGKFKKWKQNGACLLVTAFLSLLIWVAWMTMYLFGNAELRQGDAWGDPTLAITLVASGWVFVIFHAIPEIHCTILPAPQENTPNYFDTSQPRMRETAFEEDVQLPRTYMENKAFSMDEHNAALRTAGFRNGSVGNRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPTYTGRHLW", "length": 387 }, "evidence": [ { "id": "E1BT99", "url": "https://omabrowser.org/oma/group/E1BT99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q923Z0-1", "protein_name": "G protein-coupled receptor family C group 5 member B", "gene_name": "Gprc5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLVLERKMRTHQVFPLPLLLVIASVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKDKERKRPVCLHFLFLLGTLGLFGLTFAFIIQMDETICSIRRFLWGVLFALCFSCLLSQAWRVRRLVRQGTSPASWQLVSLALCLMLVQVIIATEWLVLTVLRDTKPACAYEPMDFVMALIYDMVLLAITLAQSLFTLCGKFKRWKVNGAFILVTTFLSALIWVVWMTMYLFGNSLIKQGDAWSDPTLAITLAASGWVFVIFHAIPEIHYTLLPPLQENPPNYFDTSQPRMRETAFDEEMHLPRAYMENKAFSMDEHNAALRSAVGFSNGSLEQRSSSLGKKPSSLGNRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHHW", "length": 410 }, "evidence": [ { "id": "E1BT99", "url": "https://omabrowser.org/oma/group/E1BT99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZH0-1", "protein_name": "G protein-coupled receptor family C group 5 member B", "gene_name": "GPRC5B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW", "length": 403 }, "evidence": [ { "id": "E1BT99", "url": "https://omabrowser.org/oma/group/E1BT99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WEL2-1", "protein_name": "G protein-coupled receptor, class C, group 5, member Ba precursor", "gene_name": "gprc5ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSSIKMCSVHVLVLLLAGLDVCCSEQERPAVPLGCALGPPPPYTLLCDLDAVWGVAVEVLAAAGVLSALLLLMVLLCRLHSVSEAPKRSGIGLIMLMLTGVIGLFGLSFAYLIEFSESICIIRRALWGLLFSLCFACMLAQSLRLRRLANESRSPGGCALIGLALGLTAVQGIIAAEWLLLTVLREGHPACQFQPLDFTLACVYVLALLLAALVTAALALCGKTRQWHCSVVWLLVSCVLSVLLWVAWIGFYVYGNGMLDKSPDWDDPALAVALVAQGWLVLLCHAAPEAHACLRAPPQPSAPDYFDTSQNSSRMREASLDEDIPMSHRQFVDNQRYAFDENAAGLGGGGHHNGSGGTRPSAPFRSNVYQPTEMTMILNGGAVPSAPPTYTGRQLW", "length": 397 }, "evidence": [ { "id": "E1BT99", "url": "https://omabrowser.org/oma/group/E1BT99/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" }, { "name": "protein kinase activator activity", "id": "GO:0030295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030295", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" }, { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell volume homeostasis", "id": "GO:0006884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006884", "evidence": [ { "database": "UniProtKB", "id": "E1BT99", "url": "https://www.uniprot.org/uniprotkb/E1BT99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BT99-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 387, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BT99-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BT99" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BT99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT99" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 144, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 }, { "start_pos": 344, "end_pos": 346 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTE6-1", "uniprot_ac": "E1BTE6", "uniprot_id": "E1BTE6_CHICK", "mass": { "chemical_mass": 10925.0, "monoisotopic_mass": 10925.0 }, "refseq": { "ac": "NP_001264952", "name": "uncharacterized protein C17orf67 homolog precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264952" }, "gene_names": [ { "name": "C17orf67", "type": "recommended", "evidence": [ { "id": "E1BTE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE6" } ] }, { "name": "C17orf67", "type": "synonym", "evidence": [ { "id": "NP_001264952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264952" } ] }, { "name": "C18H17ORF67", "type": "synonym", "evidence": [ { "id": "NP_001264952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264952" } ] } ], "protein_names": [ { "name": "C17orf67 homolog", "type": "synonym", "evidence": [ { "id": "E1BTE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTE6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C17orf67 homolog precursor", "type": "synonym", "evidence": [ { "id": "NP_001264952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264952" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU217376.1, CR405869.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN05341171 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000317.1. On May 5, 2013 this sequence version replaced XP_429510.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001264952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264952" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTE6", "url": "https://www.uniprot.org/uniprotkb/E1BTE6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C17orf67", "url": "https://www.uniprot.org/uniprotkb/E1BTE6", "locus": { "chromosome": "18", "start_pos": 6889284, "end_pos": 6895735, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029578", "url": "https://www.ensembl.org/id/ENSGALG00010029578" } ] } } ], "crossref": [ { "id": "E1BTE6", "url": "https://alphafold.ebi.ac.uk/entry/E1BTE6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000024428", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000024428", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417400", "url": "https://www.ncbi.nlm.nih.gov/gene/417400", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417400", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417400", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETNMEYW", "url": "https://omabrowser.org/oma/group/ETNMEYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BTE6", "url": "https://www.orthodb.org/?gene=E1BTE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48415", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48415", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48415:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48415:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264952", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BTE6", "url": "https://www.uniprot.org/uniprotkb/E1BTE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTE6-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQLLVFIFLLVLMTAFTDTSPILTEKEAKQILRTRREDRQRKAGFPDEPMREHMLYLQRLEQRSEEQFLEHWLNPHCLPHCNRDLVHPI", "length": 90, "header": "tr|E1BTE6-1|E1BTE6_CHICK Isoform 1 of C17orf67 homolog OS=Gallus gallus OX=9031 GN=C17orf67 PE=4 SV=2 CANONICAL=E1BTE6-1" }, "isoforms": [ { "isoform_ac": "E1BTE6-1", "url": "https://www.uniprot.org/uniprotkb/E1BTE6/entry#E1BTE6-1", "sequence": { "sequence": "MKQLLVFIFLLVLMTAFTDTSPILTEKEAKQILRTRREDRQRKAGFPDEPMREHMLYLQRLEQRSEEQFLEHWLNPHCLPHCNRDLVHPI", "length": 90, "header": "tr|E1BTE6-1|E1BTE6_CHICK Isoform 1 of C17orf67 homolog OS=Gallus gallus OX=9031 GN=C17orf67 PE=4 SV=2 CANONICAL=E1BTE6-1" }, "locus": { "chromosome": "18", "start_pos": 6894850, "end_pos": 6891149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071494.1", "url": "https://www.ensembl.org/id/ENSGALT00010071494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044184.1", "url": "https://www.ensembl.org/id/ENSGALP00010044184.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417400", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BDH1-1", "protein_name": "Chromosome 19 C17orf67 homolog", "gene_name": "C19H17orf67", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKGFFVLVLYLTLLIFFSGASPILTEKQAKQLLRSRRHDRPSKPGFPDEPMREYMHHLLLLEHRAEEQFLEHWLNPHCKPHCDRNLVHPI", "length": 90 }, "evidence": [ { "id": "E1BTE6", "url": "https://omabrowser.org/oma/group/E1BTE6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H1C8-1", "protein_name": "Uncharacterized protein C17orf67 homolog", "gene_name": "CUNH17orf67", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKLFVLVLALTLLVFSSEASPILTEKQAKQLLRSRRQDRPSKPGFPDEPIREYVHHLLALEHRAEEQFLEHWLNPHCKPHCDRNLVHPV", "length": 90 }, "evidence": [ { "id": "E1BTE6", "url": "https://omabrowser.org/oma/group/E1BTE6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0CD95-1", "protein_name": "Uncharacterized protein C17orf67 homolog", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKLFVLVFALTLLAFSSEASPILTEKQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNPHCKPHCDRNIVQPV", "length": 90 }, "evidence": [ { "id": "E1BTE6", "url": "https://omabrowser.org/oma/group/E1BTE6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0P5P2-1", "protein_name": "Uncharacterized protein C17orf67", "gene_name": "C17orf67", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKTLPVLVLSLTLLTVFSETSPILTEKQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNPHCKPHCDRNRIHPV", "length": 90 }, "evidence": [ { "id": "E1BTE6", "url": "https://omabrowser.org/oma/group/E1BTE6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3V3I5-1", "protein_name": "Uncharacterized protein C17orf67 homolog", "gene_name": "Gm525", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLFVLVFALALLAFSSDASPILTEKQAKQLLRSRRQDRPNKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNPHCKPHCDRNIVHPV", "length": 90 }, "evidence": [ { "id": "E1BTE6", "url": "https://omabrowser.org/oma/group/E1BTE6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BTE6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 90, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BTE6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BTE6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTL3-1", "uniprot_ac": "E1BTL3", "uniprot_id": "E1BTL3_CHICK", "mass": { "chemical_mass": 36068.0, "monoisotopic_mass": 36068.0 }, "refseq": { "ac": "XP_421193", "name": "retinol dehydrogenase 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421193" }, "gene_names": [ { "name": "RDH11", "type": "recommended", "evidence": [ { "id": "E1BTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTL3" } ] }, { "name": "RDH11", "type": "synonym", "evidence": [ { "id": "XP_421193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421193" } ] } ], "protein_names": [ { "name": "NADP-retinol dehydrogenase", "type": "recommended", "evidence": [ { "id": "E1BTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTL3/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.300", "type": "synonym", "evidence": [ { "id": "E1BTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTL3/entry#names_and_taxonomy" } ] }, { "name": "retinol dehydrogenase 12", "type": "synonym", "evidence": [ { "id": "XP_421193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421193" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421193" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTL3", "url": "https://www.uniprot.org/uniprotkb/E1BTL3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RDH11", "url": "https://www.uniprot.org/uniprotkb/E1BTL3", "locus": { "chromosome": "5", "start_pos": 28415131, "end_pos": 28406168, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019925", "url": "https://www.ensembl.org/id/ENSGALG00010019925" } ] } } ], "crossref": [ { "id": "E1BTL3", "url": "https://alphafold.ebi.ac.uk/entry/E1BTL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009538", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009538", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423274", "url": "https://www.ncbi.nlm.nih.gov/gene/423274", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423274", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423274", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "APHIRRY", "url": "https://omabrowser.org/oma/group/APHIRRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BTL3", "url": "https://www.orthodb.org/?gene=E1BTL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2453902", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5365859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975634", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_421193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421193", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25033", "url": "https://www.rhea-db.org/rhea/25033", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1BTL3", "url": "https://www.uniprot.org/uniprotkb/E1BTL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTL3-1", "url": "https://www.uniprot.org/uniprotkb/E1BTL3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPAAGMLSCWGAVLGAAVSVPLLLLAAAPYVRRYVAGGRCRSTARLDGKVAVITGANTGIGKETARELARRGARVIVACRDIAKAEAAAREIRAETDNQEVIVKKLDLADTRSIREFANSFLAEEKELHILINNAGVMLCPYSKTADGFEMHLGVNHLGHFLLTFLLLERLKQSAPSRIVNVSSLAHHGGRIRFHDLNGEKSYNRGLAYCHSKLANVLFTRELARRLQGTKVTANSLHPGSVHSELVRHSFVMTWLWRIFSFFLKTPWEGAQTSVYCAVAEELESVTGQYFSDCQPAYVSPWGRDDETAKKLWNVSCELLGIQWD", "length": 326, "header": "tr|E1BTL3-1|E1BTL3_CHICK Isoform 1 of NADP-retinol dehydrogenase OS=Gallus gallus OX=9031 GN=RDH11 PE=1 SV=2 CANONICAL=E1BTL3-1" }, "isoforms": [ { "isoform_ac": "E1BTL3-1", "url": "https://www.uniprot.org/uniprotkb/E1BTL3/entry#E1BTL3-1", "sequence": { "sequence": "MEPAAGMLSCWGAVLGAAVSVPLLLLAAAPYVRRYVAGGRCRSTARLDGKVAVITGANTGIGKETARELARRGARVIVACRDIAKAEAAAREIRAETDNQEVIVKKLDLADTRSIREFANSFLAEEKELHILINNAGVMLCPYSKTADGFEMHLGVNHLGHFLLTFLLLERLKQSAPSRIVNVSSLAHHGGRIRFHDLNGEKSYNRGLAYCHSKLANVLFTRELARRLQGTKVTANSLHPGSVHSELVRHSFVMTWLWRIFSFFLKTPWEGAQTSVYCAVAEELESVTGQYFSDCQPAYVSPWGRDDETAKKLWNVSCELLGIQWD", "length": 326, "header": "tr|E1BTL3-1|E1BTL3_CHICK Isoform 1 of NADP-retinol dehydrogenase OS=Gallus gallus OX=9031 GN=RDH11 PE=1 SV=2 CANONICAL=E1BTL3-1" }, "locus": { "chromosome": "5", "start_pos": 28411949, "end_pos": 28406202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048116.1", "url": "https://www.ensembl.org/id/ENSGALT00010048116.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028392.1", "url": "https://www.ensembl.org/id/ENSGALP00010028392.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423274", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423274", "resource": "KEGG Pathway" }, { "id": "R-GGA-2453902", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2453902", "resource": "Reactome", "description": "The canonical retinoid cycle in rods (twilight vision)" }, { "id": "R-GGA-5365859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "resource": "Reactome", "description": "RA biosynthesis pathway" }, { "id": "R-GGA-975634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975634", "resource": "Reactome", "description": "Retinoid metabolism and transport" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BM93-1", "protein_name": "NADP-retinol dehydrogenase", "gene_name": "RDH11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGVLLLLLLLPFLLYIAAPQIRKMLSSGVCTSTIQLPGKVAVVTGANAGIGKETAKELARRGARVYLACRDVQNGELVAREIQMMTGNQQVLVRKLDLADTKSIRAFAKRFLEEEKHLHILINNAGVMMCPYSKTADGFEMHMGVNHLGHFLLTHLLLEKLEESAPSRVVNVSSLAHLLGRIHFHNLQGEKFYQSGLAYCHSKLANILFTQELARRLKASGSGVTVYSVHPGTVNSELVRHSALMRWIWWIFSFFIKTPQQGAQTSLYCALTEGLEVLSGNHFSDCHVAWVSAQARNETVARRLWDVSCDLLGIPVDWLMMAAGPKRSLKQTTQHTLPK", "length": 340 }, "evidence": [ { "id": "E1BTL3", "url": "https://omabrowser.org/oma/group/E1BTL3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O22985-1", "protein_name": "NAD(P)-binding Rossmann-fold superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIETGKYLLGAAGASGFGSKSTAEEVTENCDLRSITAVITGATSGIGAETARVLAKRGARLIFPARNVKAAEEAKERIVSEFPETEIVVMKLDLSSIASVRNFVADFESLDLPLNLLINNAGKLAHEHAISEDGIEMTFATNYLGHFLLTNLLLNKMIQTAEETGVQGRIVNVTSGIHGWFSGDLIEYLRLISQPKCQFDATRAYALSKLANVLHTKELSSRLQKIGANVTVNCVHPGVVRTRLTRDREGLLTDLVFFLASKLVKTVPQAAATTCYVATNPRLVNVSGKYFTDCNETTPSGLGTNSSEATKLWAASEILVTQHSKTSFDPCS", "length": 332 }, "evidence": [ { "id": "E1BTL3", "url": "https://omabrowser.org/oma/group/E1BTL3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8TC12-1", "protein_name": "Retinol dehydrogenase 11", "gene_name": "RDH11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVELMFPLLLLLLPFLLYMAAPQIRKMLSSGVCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVQSELVRHSSFMRWMWWLFSFFIKTPQQGAQTSLHCALTEGLEILSGNHFSDCHVAWVSAQARNETIARRLWDVSCDLLGLPID", "length": 318 }, "evidence": [ { "id": "E1BTL3", "url": "https://omabrowser.org/oma/group/E1BTL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYF1-1", "protein_name": "Retinol dehydrogenase 11", "gene_name": "Rdh11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFGFLLLLSLPFILYLVTPKIRKMLSSGVCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNLSSLGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKELAKRLKGSGVTTYSVHPGTVHSELTRYSSIMRWLWQLFFVFIKTPQEGAQTSLYCALTEGLESLSGSHFSDCQLAWVSYQGRNEIIARRLWDVSCDLLGLPVDW", "length": 316 }, "evidence": [ { "id": "E1BTL3", "url": "https://omabrowser.org/oma/group/E1BTL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BTL3", "url": "https://www.uniprot.org/uniprotkb/E1BTL3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "E1BTL3", "url": "https://www.uniprot.org/uniprotkb/E1BTL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular detoxification of aldehyde", "id": "GO:0110095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110095", "evidence": [ { "database": "UniProtKB", "id": "E1BTL3", "url": "https://www.uniprot.org/uniprotkb/E1BTL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25033", "name": "", "equation": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A091-1", "A0A1D5PLZ3-1", "A0A8V0ZFZ2-1", "E1BTL3-1" ], "evidence": [ { "id": "25033", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25033" } ] }, { "id": "R-GGA-2464822", "name": "RDH12 reduces atRAL to atROL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor inner segment membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-2473615" ], "enzyme_list": [ "E1BTL3-1" ], "evidence": [ { "id": "R-GGA-2464822", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2464822" } ] }, { "id": "R-GGA-5362721", "name": "RDH5,RDH11 oxidise 11cROL to 11cRAL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BTL3-1" ], "evidence": [ { "id": "R-GGA-5362721", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5362721" } ] }, { "id": "R-GGA-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-29364", "R-ALL-70106", "R-ALL-975622" ], "output_participant_list": [ "R-ALL-975599" ], "enzyme_list": [ "E1BTL3-1", "A0A8V0ZFZ2-1" ], "evidence": [ { "id": "R-GGA-5419165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419165" } ] }, { "id": "R-GGA-74872", "name": "RDH10,11 oxidise 11cROL to 11cRAL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PLZ3-1", "E1BTL3-1" ], "evidence": [ { "id": "R-GGA-74872", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74872" } ] }, { "id": "R-GGA-975629", "name": "RDH11 reduces RBP2:atRAL to RBP2:atROL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1BTL3-1" ], "evidence": [ { "id": "R-GGA-975629", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975629" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2473615", "participant_name": "atROL [cytosol]", "crossref": [ { "id": "8144182", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000003831417", "database": "ZINC", "url": "" }, { "id": "17336", "database": "ChEBI", "url": "" }, { "id": "C00473", "database": "COMPOUND", "url": "" }, { "id": "HMDB0000305", "database": "HMDB Metabolite", "url": "" }, { "id": "4053", "database": "Guide to Pharmacology - Ligands", "url": "" } ] }, { "participant_id": "R-ALL-29364", "participant_name": "NADPH [cytosol]", "crossref": [ { "id": "57783", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215411", "database": "ZINC", "url": "" }, { "id": "C00005", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-70106", "participant_name": "H+ [cytosol]", "crossref": [ { "id": "15378", "database": "ChEBI", "url": "" }, { "id": "8145820", "database": "PubChem Substance", "url": "" }, { "id": "C00080", "database": "COMPOUND", "url": "" }, { "id": "HMDB0059597", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-975599", "participant_name": "atROL [cytosol]", "crossref": [ { "id": "C00473", "database": "COMPOUND", "url": "" }, { "id": "8144182", "database": "PubChem Substance", "url": "" }, { "id": "17336", "database": "ChEBI", "url": "" }, { "id": "4053", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003831417", "database": "ZINC", "url": "" }, { "id": "HMDB0000305", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-975622", "participant_name": "atRAL [cytosol]", "crossref": [ { "id": "17898", "database": "ChEBI", "url": "" }, { "id": "C00376", "database": "COMPOUND", "url": "" }, { "id": "8143959", "database": "PubChem Substance", "url": "" }, { "id": "2350", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000004228262", "database": "ZINC", "url": "" }, { "id": "HMDB0001358", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PLZ3", "gene_name": "RDH10", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A1D5PLZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLZ3" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A1D5PLZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLZ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZFZ2", "gene_name": "DHRS3", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A8V0ZFZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ2" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8V0ZFZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ2" } ] } ] }, { "uniprot_ac": "A0A8V1A091", "gene_name": "RDH8L2", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A8V1A091", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A091" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8V1A091", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A091" } ] } ] }, { "uniprot_ac": "E1BTL3", "gene_name": "RDH11", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "E1BTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTL3" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "E1BTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTL3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BTL3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 326, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BTL3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BTL3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.300", "ec_name": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "1.1.1.300", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300" }, { "id": "1.1.1.300", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.300" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 315, "end_pos": 317 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTP9-1", "uniprot_ac": "E1BTP9", "uniprot_id": "E1BTP9_CHICK", "mass": { "chemical_mass": 86634.0, "monoisotopic_mass": 86634.0 }, "refseq": { "ac": "NP_001244196", "name": "transcriptional regulator QRICH1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244196" }, "gene_names": [ { "name": "QRICH1", "type": "recommended", "evidence": [ { "id": "E1BTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ] }, { "name": "QRICH1", "type": "synonym", "evidence": [ { "id": "NP_001244196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244196" } ] } ], "protein_names": [ { "name": "Glutamine rich 1", "type": "synonym", "evidence": [ { "id": "E1BTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTP9/entry#names_and_taxonomy" } ] }, { "name": "transcriptional regulator QRICH1", "type": "synonym", "evidence": [ { "id": "NP_001244196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244196" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267658.25995.1, SRR13267654.51597.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000252.1. On Mar 25, 2012 this sequence version replaced XP_003642053.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001244196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244196" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "QRICH1", "url": "https://www.uniprot.org/uniprotkb/E1BTP9", "locus": { "chromosome": "12", "start_pos": 11808760, "end_pos": 11786736, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020630", "url": "https://www.ensembl.org/id/ENSGALG00010020630" } ] } } ], "crossref": [ { "id": "E1BTP9", "url": "https://alphafold.ebi.ac.uk/entry/E1BTP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006867", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006867", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01671", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01671", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858758", "url": "https://www.ncbi.nlm.nih.gov/gene/100858758", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858758", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858758", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVQIHEA", "url": "https://omabrowser.org/oma/group/QVQIHEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PB96", "url": "https://www.orthodb.org/?gene=A0A1D5PB96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTP9", "url": "https://www.orthodb.org/?gene=E1BTP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001244196", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PB96", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PB96-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTP9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNSLENTISFEEYIRVKARTIPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQQQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQQLSPQLTVHQASEQPIQVQVQIQGQGQQQASQTIQSQCLQSPSPSQLQAAQIQVQHVQTAQQIQAAEIQEEHIQHQQIQAQLVAGQAITGGQQIQIQTVGALSPPPSQQGSPREGERRISTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDLQQQNITHIAIPQEAYNAVHVSGSPTTLTTVKLEDDKDKMVGSTSVVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQQQQPTPQEQGQQQQQLQVTCSAQTVQVAEVEQQQQPQTSPELLLPNSLKPEEGLEVWKSWAQTKNAELEKEAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGDGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYIRFTEWLHEVLKDVQPRVSPLGYVLSSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKNPSNPKDKSTSIRYLKAHGAHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSIQPISREQMEQMLTRILVIREIQEAIAVANASTMH", "length": 773, "header": "tr|E1BTP9-1|E1BTP9_CHICK Isoform 1 of Glutamine rich 1 OS=Gallus gallus OX=9031 GN=QRICH1 PE=1 SV=3 CANONICAL=E1BTP9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PB96-1", "url": "https://www.uniprot.org/uniprotkb/E1BTP9/entry#A0A1D5PB96-1", "sequence": { "sequence": "MNNSLENTISFEEYIRVKARTIPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQQQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQQLSPQLTVHQASEQPIQVQVQIQGQGQQQASQTIQSQCLQSPSPSQLQAAQIQVQHVQTAQQIQAAEIQEEHIQHQQIQAQLVAGQAITGGQQIQIQTVGALSPPPSQQGSPREGERRISTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDLQQQNITHIAIPQEAYNAVHVSGSPTTLTTVKLEDDKDKMFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQQQQPTPQEQGQQQQQLQVTCSAQTVQVAEVEQQQQPQTSPELLLPNSLKPEEGLEVWKSWAQTKNAELEKEAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGDGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYIRFTEWLHEVLKDVQPRVSPLGYVLSSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKNPSNPKDKSTSIRYLKAHGAHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSIQPISREQMEQMLTRILVIREIQEAIAVANASTMH", "length": 747, "header": "tr|A0A1D5PB96-1|A0A1D5PB96_CHICK Computationally mapped isoform of Glutamine rich 1 OS=Gallus gallus OX=9031 GN=QRICH1 PE=1 SV=1 CANONICAL=E1BTP9-1" }, "locus": { "chromosome": "12", "start_pos": 11808018, "end_pos": 11791133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049792.1", "url": "https://www.ensembl.org/id/ENSGALT00010049792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029422.1", "url": "https://www.ensembl.org/id/ENSGALP00010029422.1" } ] } }, { "isoform_ac": "E1BTP9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTP9/entry#E1BTP9-1", "sequence": { "sequence": "MNNSLENTISFEEYIRVKARTIPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQQQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQQLSPQLTVHQASEQPIQVQVQIQGQGQQQASQTIQSQCLQSPSPSQLQAAQIQVQHVQTAQQIQAAEIQEEHIQHQQIQAQLVAGQAITGGQQIQIQTVGALSPPPSQQGSPREGERRISTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDLQQQNITHIAIPQEAYNAVHVSGSPTTLTTVKLEDDKDKMVGSTSVVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQQQQPTPQEQGQQQQQLQVTCSAQTVQVAEVEQQQQPQTSPELLLPNSLKPEEGLEVWKSWAQTKNAELEKEAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGDGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYIRFTEWLHEVLKDVQPRVSPLGYVLSSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKNPSNPKDKSTSIRYLKAHGAHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSIQPISREQMEQMLTRILVIREIQEAIAVANASTMH", "length": 773, "header": "tr|E1BTP9-1|E1BTP9_CHICK Isoform 1 of Glutamine rich 1 OS=Gallus gallus OX=9031 GN=QRICH1 PE=1 SV=3 CANONICAL=E1BTP9-1" }, "locus": { "chromosome": "12", "start_pos": 11808018, "end_pos": 11791133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049793.1", "url": "https://www.ensembl.org/id/ENSGALT00010049793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029423.1", "url": "https://www.ensembl.org/id/ENSGALP00010029423.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858758", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858758", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AW46-1", "protein_name": "Glutamine-rich 1", "gene_name": "Qrich1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNSLENTISFEEYIRVKARSVPQHRMKEFLDSLASKGPEALQEFQQSATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQQLSPQFTVHQPAEQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSLAGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGTTSVVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQPQQQTAQEQTPPQPQQQQQLQVTCSAQTVQVAEVEPQSQPQPSPELLLPNSLKPEEGLEVWKNWAQTKNAELEKDAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGEGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYVRFTEWLHEVLKDVQPRVTPLGYVLPSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKSPSNPKDKSTSIRYLKALGIHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSVQPISREQMGQMLTRILVIREIQEAIAVANATTMH", "length": 777 }, "evidence": [ { "id": "E1BTP9", "url": "https://omabrowser.org/oma/group/E1BTP9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IB72-1", "protein_name": "Glutamine-rich protein 1", "gene_name": "Qrich1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNNSLENTISFEEYIRVKARSVPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQQLSPQFTVHQPAEQPIQVQVQIQGQPPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEDHIPHQQIQAQLVAGQSLAGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGATSVVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQPQQQTAQEQTPPPPQQQQQLQVTCSAQTVQVAEVEPQSQPQPSPELLLPNSLKPEEGLEVWKNWAQTKNAELEKDAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGEGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYVRFTEWLHEVLKDVQPRVTPLGYVLPSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKNPSNPKDKSTSIRYLKALGIHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSVQPISREQMGQMLTRILVIREIQEAIAVASATTMH", "length": 777 }, "evidence": [ { "id": "E1BTP9", "url": "https://omabrowser.org/oma/group/E1BTP9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0P5J0-1", "protein_name": "Transcriptional regulator QRICH1", "gene_name": "QRICH1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNNSLENTISFEEYIRVKARSVPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQPEQQIQVQQPQQVQVQVQVQQSPQQVSAQQLSPQLTVHQPAEQPIHVQVQIQGQAAQPAAPSIQTPSLQSPSPSQLQAAQIQVQHMQAAQQIQAPEIPEEHIPHQQIQAQLVAGQSLAGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGTTSVVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQPQQQTPQEQTPPPPQQQQQQQLQVTCSAQTVQVAEVEPQSQPQPSPELLLPNSLKPEEGLEVWKNWAQTKNAELEKDAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGEGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYVRFTEWLHEVLKDVQPRVTPLGYVLPSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKNPSNPKDKSTSIRYLKALGIHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSVQPISREQMGQMLTRILVIREIQEAIAVASASTMH", "length": 779 }, "evidence": [ { "id": "E1BTP9", "url": "https://omabrowser.org/oma/group/E1BTP9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2TAL8-1", "protein_name": "Transcriptional regulator QRICH1", "gene_name": "QRICH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNSLENTISFEEYIRVKARSVPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQLSPQLTVHQPTEQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSLAGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVKLEDDKEKMVGTTSVVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQPQQQTPQEQTPPPQQQQQQLQVTCSAQTVQVAEVEPQSQPQPSPELLLPNSLKPEEGLEVWKNWAQTKNAELEKDAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGEGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYVRFTEWLHEVLKDVQPRVTPLGYVLPSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKNPSNPKDKSTSIRYLKALGIHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSVQPISREQMGQMLTRILVIREIQEAIAVANASTMH", "length": 776 }, "evidence": [ { "id": "E1BTP9", "url": "https://omabrowser.org/oma/group/E1BTP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UA37-1", "protein_name": "Transcriptional regulator QRICH1", "gene_name": "Qrich1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNNSLENTISFEEYIRVKARSVPQHRMKEFLDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACPVTTSVQPQTQQEQQIQVQQPQQVQVQVQVQQSPQQVSAQQLSPQFTVHQPAEQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHVQAAQQIQAAEIPEEHIPHQQIQAQLVAGQSLAGGQQIQIQTVGALSPPPSQQGSPREGERRVGTASVLQPVKKRKVDMPITVSYAISGQPVATVLAIPQGQQQSYVSLRPDLLTVDSAHLYSATGTITSPTGETWTIPVYSAQPRGDPQQQSITHIAIPQEAYNAVHVSGSPKALAAVKLEDDKEKMVGTTSVVKNSHEEVVQTLANSLFPAQFMNGNIHIPVAVQAVAGTYQNTAQTVHIWDPQQQPQQQTAQEQTPPPQQQQQQLQVTCSAQTVQVAEVEPQSQPQPSPELLLPNSLKPEEGLEVWKNWAQTKNAELEKDAQNRLAPIGRRQLLRFQEDLISSAVAELNYGLCLMTREARNGEGEPYDPDVLYYIFLCIQKYLFENGRVDDIFSDLYYVRFTEWLHEVLKDVQPRVTPLGYVLPSHVTEEMLWECKQLGAHSPSTLLTTLMFFNTKYFLLKTVDQHMKLAFSKVLRQTKKSPSNPKDKSTSIRYLKALGIHQTGQKVTDDMYAEQTENPENPLRCPIKLYDFYLFKCPQSVKGRNDTFYLTPEPVVAPNSPIWYSVQPISREQMGQMLTRILVIREIQEAIAVANATTMH", "length": 777 }, "evidence": [ { "id": "E1BTP9", "url": "https://omabrowser.org/oma/group/E1BTP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "id": "GO:0070059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070059", "evidence": [ { "database": "UniProtKB", "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ], "pmid": "" }, { "name": "PERK-mediated unfolded protein response", "id": "GO:0036499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036499", "evidence": [ { "database": "UniProtKB", "id": "E1BTP9", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BTP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 773, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BTP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BTP9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" }, { "id": "PF25561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "QRICH1-like", "eco_id": "ECO_0000259", "start_pos": 470, "end_pos": 584, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BTP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTP9" }, { "id": "PF12012", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZMYM2-like/QRICH1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 597, "end_pos": 755, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 2, "end_pos": 4 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 718, "end_pos": 720 }, { "start_pos": 768, "end_pos": 770 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTS3-1", "uniprot_ac": "E1BTS3", "uniprot_id": "E1BTS3_CHICK", "mass": { "chemical_mass": 10303.0, "monoisotopic_mass": 10303.0 }, "refseq": { "ac": "NP_001289110", "name": "electron transfer flavoprotein regulatory factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289110" }, "gene_names": [ { "name": "ETFRF1", "type": "recommended", "evidence": [ { "id": "E1BTS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTS3" } ] }, { "name": "ETFRF1", "type": "synonym", "evidence": [ { "id": "NP_001289110", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289110" } ] }, { "name": "LYRM5", "type": "synonym", "evidence": [ { "id": "NP_001289110", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289110" } ] } ], "protein_names": [ { "name": "Electron transfer flavoprotein regulatory factor 1", "type": "synonym", "evidence": [ { "id": "E1BTS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTS3/entry#names_and_taxonomy" } ] }, { "name": "LYR motif containing 5", "type": "synonym", "evidence": [ { "id": "NP_001289110", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289110" } ] }, { "name": "electron transfer flavoprotein regulatory factor 1", "type": "synonym", "evidence": [ { "id": "NP_001289110", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289110" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX932178.1, CR353895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX932178.1. On Oct 4, 2014 this sequence version replaced XP_004938052.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289110", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289110" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTS3", "url": "https://www.uniprot.org/uniprotkb/E1BTS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ETFRF1", "url": "https://www.uniprot.org/uniprotkb/E1BTS3", "locus": { "chromosome": "1", "start_pos": 67272487, "end_pos": 67260490, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014213", "url": "https://www.ensembl.org/id/ENSGALG00010014213" } ] } } ], "crossref": [ { "id": "E1BTS3", "url": "https://alphafold.ebi.ac.uk/entry/E1BTS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014031", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014031", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "776112", "url": "https://www.ncbi.nlm.nih.gov/gene/776112", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776112", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776112", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRAFMSK", "url": "https://omabrowser.org/oma/group/HRAFMSK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BTS3", "url": "https://www.orthodb.org/?gene=E1BTS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21024:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21024:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001289110", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289110", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BTS3", "url": "https://www.uniprot.org/uniprotkb/E1BTS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTS3-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSLRGEVLNLYKNLLYLGREYPKGADYFRSRLKAAFLKNKDVKDPEKIKQLIARGEFVIKELEALYFLRKYRAMKKRYYSDDKE", "length": 86, "header": "tr|E1BTS3-1|E1BTS3_CHICK Isoform 1 of Electron transfer flavoprotein regulatory factor 1 OS=Gallus gallus OX=9031 GN=ETFRF1 PE=3 SV=1 CANONICAL=E1BTS3-1" }, "isoforms": [ { "isoform_ac": "E1BTS3-1", "url": "https://www.uniprot.org/uniprotkb/E1BTS3/entry#E1BTS3-1", "sequence": { "sequence": "MASSLRGEVLNLYKNLLYLGREYPKGADYFRSRLKAAFLKNKDVKDPEKIKQLIARGEFVIKELEALYFLRKYRAMKKRYYSDDKE", "length": 86, "header": "tr|E1BTS3-1|E1BTS3_CHICK Isoform 1 of Electron transfer flavoprotein regulatory factor 1 OS=Gallus gallus OX=9031 GN=ETFRF1 PE=3 SV=1 CANONICAL=E1BTS3-1" }, "locus": { "chromosome": "1", "start_pos": 67261359, "end_pos": 67260997, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034224.1", "url": "https://www.ensembl.org/id/ENSGALT00010034224.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020106.1", "url": "https://www.ensembl.org/id/ENSGALP00010020106.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:776112", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776112", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BTM9-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1", "gene_name": "ETFRF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKMANSLRGEVLNLYKNLLYLGRDYPKGADYFKRRLKNVFLKNKDVKDPEKIKELIARGKFVMKELEALYFLRKYRAMKQRYYSDTNTTN", "length": 90 }, "evidence": [ { "id": "E1BTS3", "url": "https://omabrowser.org/oma/group/E1BTS3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4AD58-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1", "gene_name": "Etfrf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANSLRGEVLTLYKNLLYLGRDYPKGADYFKRRLKNVFLKNKDVKDPEKIKELIARGEFVMKELEALYFLRKYRAMKQRYYSDTKN", "length": 86 }, "evidence": [ { "id": "E1BTS3", "url": "https://omabrowser.org/oma/group/E1BTS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IPR1-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1", "gene_name": "ETFRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGEFVMKELEALYFLRKYRAMKQRYYSDTNKTN", "length": 90 }, "evidence": [ { "id": "E1BTS3", "url": "https://omabrowser.org/oma/group/E1BTS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91V16-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1", "gene_name": "Etfrf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSLRGEVLTLYKNLLYLGRDYPKGADYFKRRLKNVFLKNKDVEDPEKIKELIARGEFVMKELEALYFLRKYRAMKQRYYSDTKV", "length": 86 }, "evidence": [ { "id": "E1BTS3", "url": "https://omabrowser.org/oma/group/E1BTS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJG4-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1 homolog", "gene_name": "osi", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQLRSKVISLYKHLQYLGREYPGLNGPQKFRKQIHDAFMNHKDEQDPKKIVALLAQGRYLAKEVEALYSLKKYRSVKQRYSYND", "length": 85 }, "evidence": [ { "id": "E1BTS3", "url": "https://omabrowser.org/oma/group/E1BTS3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "E1BTS3", "url": "https://www.uniprot.org/uniprotkb/E1BTS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BTS3", "url": "https://www.uniprot.org/uniprotkb/E1BTS3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of oxidative phosphorylation", "id": "GO:0090324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090324", "evidence": [ { "database": "UniProtKB", "id": "E1BTS3", "url": "https://www.uniprot.org/uniprotkb/E1BTS3" } ], "pmid": "" }, { "name": "negative regulation of cellular respiration", "id": "GO:1901856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901856", "evidence": [ { "database": "UniProtKB", "id": "E1BTS3", "url": "https://www.uniprot.org/uniprotkb/E1BTS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BTS3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 86, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BTS3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BTS3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BTS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTS3" }, { "id": "PF05347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Complex 1 LYR protein", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 61, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTV9-1", "uniprot_ac": "E1BTV9", "uniprot_id": "E1BTV9_CHICK", "mass": { "chemical_mass": 57315.0, "monoisotopic_mass": 57315.0 }, "refseq": { "ac": "XP_015128468", "name": "retinoic acid-induced protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128468" }, "gene_names": [ { "name": "RAI2", "type": "recommended", "evidence": [ { "id": "E1BTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTV9" } ] }, { "name": "RAI2", "type": "synonym", "evidence": [ { "id": "XP_015128468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128468" } ] } ], "protein_names": [ { "name": "Retinoic acid induced 2", "type": "synonym", "evidence": [ { "id": "E1BTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTV9/entry#names_and_taxonomy" } ] }, { "name": "retinoic acid-induced protein 2", "type": "synonym", "evidence": [ { "id": "XP_015128468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128468" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015128468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128468" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTV9", "url": "https://www.uniprot.org/uniprotkb/E1BTV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAI2", "url": "https://www.uniprot.org/uniprotkb/E1BTV9", "locus": { "chromosome": "1", "start_pos": 120823443, "end_pos": 120858195, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002365", "url": "https://www.ensembl.org/id/ENSGALG00010002365" } ] } } ], "crossref": [ { "id": "ENSGALG00000016538", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016538", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418614", "url": "https://www.ncbi.nlm.nih.gov/gene/418614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418614", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHKWLVD", "url": "https://omabrowser.org/oma/group/QHKWLVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BTV9", "url": "https://www.orthodb.org/?gene=E1BTV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23186:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23186:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15279", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15279", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015128468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015128468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BTV9", "url": "https://www.uniprot.org/uniprotkb/E1BTV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEELYKETPNLPMDVTSPPAAMANNKLENGVAQLITAEAWNINSADLMKKALSPLVTVPAPSILTPPAESQSGVALKVAATVLQPICLGDSPVVLPIHLQVAGSAAPQMPASNATPYVMTTQGPVPLPVLLEQHVFQHLNSPLVLPPGTACPASPLHGSLFPGASAPVSQPQLLDPKPSGPGQEPVLPPVFQTPGFAAVLQDLFPSGQGALGSAPCQPPPDYATLPPQAFSSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPVPIPMPHGAEAKVAPDPPKPPVFTPQPCKGTQTPLEKEETKPFDLVHQRDFSQLSRHTVIKMGSENEALDLSMKGPPVPRACEAAPPPPSPDDGALDLSLSSCRKPGGPHGETAGSGPSAEGSPQDKPATPFAPSKAPEAAGKAEGRVVGPGSGELLRPPQKWLVEPAGRAACEPKAGGNNIEIVSTSQTAKVIVSVKDAVPAIFCGKIKGLSGVSTKNFSFKRDMPQDSVLQCYDVKSQPEPRDNAEALRKPVKNRSVKLKKMNSPEIHILPIKKQRLAAFFPRK", "length": 548, "header": "tr|E1BTV9-1|E1BTV9_CHICK Isoform 1 of Retinoic acid induced 2 OS=Gallus gallus OX=9031 GN=RAI2 PE=4 SV=1 CANONICAL=E1BTV9-1" }, "isoforms": [ { "isoform_ac": "E1BTV9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTV9/entry#E1BTV9-1", "sequence": { "sequence": "MEELYKETPNLPMDVTSPPAAMANNKLENGVAQLITAEAWNINSADLMKKALSPLVTVPAPSILTPPAESQSGVALKVAATVLQPICLGDSPVVLPIHLQVAGSAAPQMPASNATPYVMTTQGPVPLPVLLEQHVFQHLNSPLVLPPGTACPASPLHGSLFPGASAPVSQPQLLDPKPSGPGQEPVLPPVFQTPGFAAVLQDLFPSGQGALGSAPCQPPPDYATLPPQAFSSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPVPIPMPHGAEAKVAPDPPKPPVFTPQPCKGTQTPLEKEETKPFDLVHQRDFSQLSRHTVIKMGSENEALDLSMKGPPVPRACEAAPPPPSPDDGALDLSLSSCRKPGGPHGETAGSGPSAEGSPQDKPATPFAPSKAPEAAGKAEGRVVGPGSGELLRPPQKWLVEPAGRAACEPKAGGNNIEIVSTSQTAKVIVSVKDAVPAIFCGKIKGLSGVSTKNFSFKRDMPQDSVLQCYDVKSQPEPRDNAEALRKPVKNRSVKLKKMNSPEIHILPIKKQRLAAFFPRK", "length": 548, "header": "tr|E1BTV9-1|E1BTV9_CHICK Isoform 1 of Retinoic acid induced 2 OS=Gallus gallus OX=9031 GN=RAI2 PE=4 SV=1 CANONICAL=E1BTV9-1" }, "locus": { "chromosome": "1", "start_pos": 120826931, "end_pos": 120825288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005379.1", "url": "https://www.ensembl.org/id/ENSGALT00010005379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003218.1", "url": "https://www.ensembl.org/id/ENSGALP00010003218.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418614", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9U1J6-1", "protein_name": "Retinoic acid induced 2", "gene_name": "RAI2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDDLQSQNLAMDMSDSSPTLTNNRLENGMAQLITTEAWNINSTDLVKKALVTVPAPSILNPPAESQSGVALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNQSGNATYVMTAQGPVQLPVVLEQHVFQHLNSPLVLPPEAPGSSSTIHNNLFQGARDPEAQPQLLDLRIPSQPQEPPLPFEAVLHNLFPAQGALGPPPCQPPPGYTPVPPQPFNSPLSPLVPPATLLVPYPVIVPLPVPLPIPIPIPVPQSSEAKFSPTCPKPPSAFGLHPFKGPQSPLQKEEVKPFDLFQPREYFQLGRHTVIKMGSENEALDLSMKSVPWLKAGEVSPAMDQEDTALDLSLSAHRKPEPPPETLYDSSGSVDSPGHPVLEKLPSGMEVPFAPTTTQEAASVMESHGGGSDATEPPSQPSGEVKAENLVSESQAAKVIVSVEDTVPTIFCGKIKGLSGVSTKNFSFRREDSVFQGSDANSPGEEALGNMEALRKPTKNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK", "length": 523 }, "evidence": [ { "id": "E1BTV9", "url": "https://omabrowser.org/oma/group/E1BTV9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LJM4-1", "protein_name": "Retinoic acid induced 2", "gene_name": "Rai2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDLQSQNLSMDMTDSPPTLANNRLENGMAQLITTEAWNINSTDLVKKALVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQGAEDSEAQPQLLDLRIPSQPQEPTLPFEAVLQNLFPTQGSLGPPPCQPPPGYAPVPPQPFSSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPVPVPQSSESKFSPSFPKPPSSFGLHSFKGTQTTLEKDELKPLDILQPKEYFQLSRHTVIKMGGENEALDLSMKSVPWLKAGEASPPVFQEDAALDLSLAAHRKAEVPPETLYNTSGSADIQGHTLLEKRPSGMEMPFAPAKSREASAMMDSHSSSSNGTEMVSQPIHPGSELKPENNIEIVSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKREDSVLQGYDINSQEDESLGNTEPLRKPIKNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK", "length": 529 }, "evidence": [ { "id": "E1BTV9", "url": "https://omabrowser.org/oma/group/E1BTV9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SQQ4-1", "protein_name": "Retinoic acid induced 2", "gene_name": "RAI2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDLQSQNLSMDMTDSAPALASNRLENGMAQLITTEAWNINSTDLVKKALVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSGAVHSNLFQGAEDPEAQPQLLDLRIPSQPQEPSLPFEAVLQNLFPSQGALGPPPCQPPPGYAPVPPQPFNAPLSPLVPPATLLVPYPVIVPLPVPVPIPIPIPVPQSSESKFSPGCPKAPSSFGLQPFRGGPPAVQKEELKPFELLQPREYFQLSRHTVIKMGSENEALDLSMKSVPWLKAGDVSAPACQEDAALDLSLATHRRSEPPPPPETLCDSSGAVDGPGHAAMETPPGGGVEVPFAPATPHEAAAAAAMERHLGGSDAAEPPRQPSGEVKAENNIELGSESQAAKVIVSVEDTVPTIFCGKIKGLSGVSTKNFSFKREDAMLQGYDISSQAEESAGSAEPLRKPIKNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK", "length": 531 }, "evidence": [ { "id": "E1BTV9", "url": "https://omabrowser.org/oma/group/E1BTV9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9QVY8-1", "protein_name": "Retinoic acid-induced protein 2", "gene_name": "Rai2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDLQSQNLSMDMTDSPPTLANNRLENRMAQLITTEAWNINSTDLVKKALVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSNAIHNNLFQGAEDSEAQPQLLDLRIPSQPQEPALPFEAVLQNLFPTQGSLGPPPCQPPPGYAPVPPQPFNSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPVPVPQSTESKFSPTFPKPPSSFGLHSFKGTQTTLEKDELKPLDILQSKEYFQLSRHTVIKMGSENEALDLSMKSVPWLKAGEASPPVFQEDAALDLSLAAHRKAEAPPETLYNNSGSADIQGHTILEKLSSGMEMPFAPAKCSEASAMMESHSSNSNGTEMVSQPSHPGSELKAENNIEILSESQAAKVIVSVEDAVPAIFCGKIKGLSGVSTKNFSFKREDSVLQGYDINSQGEESLGNAEPLRKPIKNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK", "length": 529 }, "evidence": [ { "id": "E1BTV9", "url": "https://omabrowser.org/oma/group/E1BTV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5P3-1", "protein_name": "Retinoic acid-induced protein 2", "gene_name": "RAI2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDLQSQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKALVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQGAEDPEAQPQLLDLRIPSQPQEPTLPFEAVLQNLFPSQGTLGPPPCQPPPGYAPVPPQPFSSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPIPMPQSSESKFSSSFPKPPSSFGLHPFKGTQTPLEKDELKPFDILQPKEYFQLSRHTVIKMGSENEALDLSMKSVPWLKAGEVSPPIFQEDAALDLSVAAHRKSEPPPETLYDSGASVDSSGHTVMEKLPSGMEISFAPATSHEAPAMMDSHISSSDAATEMLSQPNHPSGEVKAENNIEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKREDSVLQGYDINSQGEESMGNAEPLRKPIKNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK", "length": 530 }, "evidence": [ { "id": "E1BTV9", "url": "https://omabrowser.org/oma/group/E1BTV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BTV9", "url": "https://www.uniprot.org/uniprotkb/E1BTV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "E1BTV9", "url": "https://www.uniprot.org/uniprotkb/E1BTV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 518, "end_pos": 520 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BUD5-1", "uniprot_ac": "E1BUD5", "uniprot_id": "E1BUD5_CHICK", "mass": { "chemical_mass": 38229.0, "monoisotopic_mass": 38229.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Leucine rich repeat containing 75B", "type": "synonym", "evidence": [ { "id": "E1BUD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUD5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BUD5", "url": "https://www.uniprot.org/uniprotkb/E1BUD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1BUD5", "locus": {} } ], "crossref": [ { "id": "E1BUD5", "url": "https://alphafold.ebi.ac.uk/entry/E1BUD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006588", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006588", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BUD5", "url": "https://www.orthodb.org/?gene=E1BUD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39654:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39654:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "E1BUD5", "url": "https://www.uniprot.org/uniprotkb/E1BUD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUD5-1", "url": "https://www.uniprot.org/uniprotkb/E1BUD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSRLSRQSSLEEESPGGEEPSGRADFHLSSLLLHPQKLPGVLRKTSPAPYVRRVGWLREIQATIREHKREHAVHILRLLRKDLGLEGTFLNEVLYKNATFLNLVDPISHDLLMSLARDLQCPKKEYDPWKSSDRICRQLIYHLTPHSKWHRHGMPRRKSQVCLKNSLQKKVSQGSMDLSGIPLTMRDVHRMAYYLQNNGDHLTSVDLSFTELNDDMVRLLLPFLWALPKLTHLSLNGNRLTRATMKELTDTMKDMNKFPCLAWVDLGNNVDVSSMPQPLLVGLRKRLSQQTTLPTIYEALDCDPEIPSGQEGGRPEGEEAGSTPRHAVPQQGCER", "length": 336, "header": "tr|E1BUD5-1|E1BUD5_CHICK Isoform 1 of Leucine rich repeat containing 75B OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=E1BUD5-1" }, "isoforms": [ { "isoform_ac": "E1BUD5-1", "url": "https://www.uniprot.org/uniprotkb/E1BUD5/entry#E1BUD5-1", "sequence": { "sequence": "MGSRLSRQSSLEEESPGGEEPSGRADFHLSSLLLHPQKLPGVLRKTSPAPYVRRVGWLREIQATIREHKREHAVHILRLLRKDLGLEGTFLNEVLYKNATFLNLVDPISHDLLMSLARDLQCPKKEYDPWKSSDRICRQLIYHLTPHSKWHRHGMPRRKSQVCLKNSLQKKVSQGSMDLSGIPLTMRDVHRMAYYLQNNGDHLTSVDLSFTELNDDMVRLLLPFLWALPKLTHLSLNGNRLTRATMKELTDTMKDMNKFPCLAWVDLGNNVDVSSMPQPLLVGLRKRLSQQTTLPTIYEALDCDPEIPSGQEGGRPEGEEAGSTPRHAVPQQGCER", "length": 336, "header": "tr|E1BUD5-1|E1BUD5_CHICK Isoform 1 of Leucine rich repeat containing 75B OS=Gallus gallus OX=9031 GN= PE=4 SV=2 CANONICAL=E1BUD5-1" }, "locus": { "chromosome": "15", "start_pos": 8425080, "end_pos": 8412958, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010064182.1", "url": "https://www.ensembl.org/id/ENSGALT00010064182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039458.1", "url": "https://www.ensembl.org/id/ENSGALP00010039458.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BUD5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 336, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BUD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BUD5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BUJ9-1", "uniprot_ac": "E1BUJ9", "uniprot_id": "E1BUJ9_CHICK", "mass": { "chemical_mass": 49487.0, "monoisotopic_mass": 49487.0 }, "refseq": { "ac": "NP_001257923", "name": "F-box/LRR-repeat protein 21", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257923" }, "gene_names": [ { "name": "FBXL21", "type": "recommended", "evidence": [ { "id": "E1BUJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ] }, { "name": "FBXL21", "type": "synonym", "evidence": [ { "id": "NP_001257923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257923" } ] } ], "protein_names": [ { "name": "F-box and leucine rich repeat protein 21", "type": "synonym", "evidence": [ { "id": "E1BUJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 21", "type": "synonym", "evidence": [ { "id": "NP_001257923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257923" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## CDS exon combination :: SRR12888534.167766.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA103992432, SAMEA103992484 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On Aug 22, 2012 this sequence version replaced XP_414624.3. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001257923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257923" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL21", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9", "locus": { "chromosome": "13", "start_pos": 14820415, "end_pos": 14828636, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012859", "url": "https://www.ensembl.org/id/ENSGALG00010012859" } ] } } ], "crossref": [ { "id": "E1BUJ9", "url": "https://alphafold.ebi.ac.uk/entry/E1BUJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006327", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006327", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22179", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22179", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23957", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23957", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416306", "url": "https://www.ncbi.nlm.nih.gov/gene/416306", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416306", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416306", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWFPDMM", "url": "https://omabrowser.org/oma/group/LWFPDMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BUJ9", "url": "https://www.orthodb.org/?gene=E1BUJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10224:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10224:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1BUJ9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1BUJ9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001257923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001257923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMKRARQKVMVDNAVPQTSQENKKQKTCLYGSAFSESDPHASIDWGSLPHHVILRIFQFLPLVDRARASSVCRRWNEVFHIPDLWRRFEFELSQPATSYLKSTHPDLIQQIIKRHADHLQYVSFKVDSSTESAEAACNILSQLVNCSIKTLGLISTAKPSFMNVSKAHFASALTVVFVNSKSLSSIKIDDTPLDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGVLCVADQCHGLKELALNYYILSDELLLALSSEKHVDLEHLRIDVVSENPGQVEFHTIKKQSWDAFVKHSPKVNIVMYFFLYEEEFDAFFREETPVTHLYFGRAVSKAMLGRIGLNCPRLIELVVCANGLQPLDDELIQIAQRCKNLTAMGLGECEVTCRGFIEFVKMCGGRLTQLSIMEEVLIPDNDYSLDRLHLEVSKHLGRMWFPDMMPTW", "length": 437, "header": "tr|E1BUJ9-1|E1BUJ9_CHICK Isoform 1 of F-box and leucine rich repeat protein 21 OS=Gallus gallus OX=9031 GN=FBXL21 PE=4 SV=2 CANONICAL=E1BUJ9-1" }, "isoforms": [ { "isoform_ac": "E1BUJ9-1", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9/entry#E1BUJ9-1", "sequence": { "sequence": "MMKRARQKVMVDNAVPQTSQENKKQKTCLYGSAFSESDPHASIDWGSLPHHVILRIFQFLPLVDRARASSVCRRWNEVFHIPDLWRRFEFELSQPATSYLKSTHPDLIQQIIKRHADHLQYVSFKVDSSTESAEAACNILSQLVNCSIKTLGLISTAKPSFMNVSKAHFASALTVVFVNSKSLSSIKIDDTPLDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGVLCVADQCHGLKELALNYYILSDELLLALSSEKHVDLEHLRIDVVSENPGQVEFHTIKKQSWDAFVKHSPKVNIVMYFFLYEEEFDAFFREETPVTHLYFGRAVSKAMLGRIGLNCPRLIELVVCANGLQPLDDELIQIAQRCKNLTAMGLGECEVTCRGFIEFVKMCGGRLTQLSIMEEVLIPDNDYSLDRLHLEVSKHLGRMWFPDMMPTW", "length": 437, "header": "tr|E1BUJ9-1|E1BUJ9_CHICK Isoform 1 of F-box and leucine rich repeat protein 21 OS=Gallus gallus OX=9031 GN=FBXL21 PE=4 SV=2 CANONICAL=E1BUJ9-1" }, "locus": { "chromosome": "13", "start_pos": 14826038, "end_pos": 14822074, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030840.1", "url": "https://www.ensembl.org/id/ENSGALT00010030840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017894.1", "url": "https://www.ensembl.org/id/ENSGALP00010017894.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416306", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416306", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z851-1", "protein_name": "F-box and leucine-rich repeat protein 21", "gene_name": "Fbxl21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRNNFSTVNKVVHSSPAVKQPKRGLCTSLRQTQMLSALLDWGTLPHHVILRIFQYLPLVDRARASSVCRSWNEVFHIPDLWRKFEFELNQSATSYFKSTHPDLIQQIIKKHAAHLQYVSFKVDSSTESAEAACHILSQLVNCSIQTLGLISTAKPSFMNMPKSHFVSALTVVFVNSKSLSSIKIEDTPVDDPSLKILVANNSDTLRLLKMSSCPHVSSDGILCVADHCQGLRELALNYYILSDELLLALSSETHVNLEHLRIDVVSENPGQIKFHSIKKPSWDALVKHSPGVNVVMYFFLYEEEFDTFFKEETPVTHLYFGRSVSRTILGRIGLNCPRLIELVVCANGLQPLDSELIRIAEHCKNLTALGLSECEVSCSAFVEFVRLCGRRLTQLSLMEEVLVPDDRYTPDEVHTEVSKHLGRVWFPDVMPVW", "length": 434 }, "evidence": [ { "id": "E1BUJ9", "url": "https://omabrowser.org/oma/group/E1BUJ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F6Z4-1", "protein_name": "F-box/LRR-repeat protein 3", "gene_name": "fbxl3l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPFYVDAEGWNKMKRGRSKCQSFTPSEGRNKRHRSTTPVYVQTGSTNFQNATEETWGNLPHHVVLHIFQYLSLVDRARASSVCRRWNEVFHIPDLWRRFEFELNQPATSYLRSTHPDLIQQIIKRHAQHLQYVSFKVDSCTESAEAACNILSQLVNCTIKTLGLISTARPSFMDVSQSHFVSALTVVFVNSKSLSSIKIDDTPVDDPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHVHLEHLRIDVVSENPGQTQFHTIKKSSWDALIRHSPQVNIVMYFFLYEEEFEPFFREETPVTHLYFGRAVSKDMLGRIGLNCPRLVELVVCANGLEPLDEELIRIADRCKSLTAIGLGECEVTCSGFMEFVKMCGGRLSQLSIMEEVLIPDNTYNIEQIHSEVSKHLGRIWFPDMMPTW", "length": 448 }, "evidence": [ { "id": "E1BUJ9", "url": "https://omabrowser.org/oma/group/E1BUJ9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BFZ4-1", "protein_name": "F-box/LRR-repeat protein 21", "gene_name": "Fbxl21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRNNFSAVNKVVQSSPVVKQPKRGLCSSLRQTHALSVLLDWGTLPHHVILQIFQYLPLIDRARASSVCRRWNEVFHIPDLWRKFEFELNQSATSYFKSTHPDLIQQIIKKHAAHLQYVSFKVDSSTESAEAACDILSQLVNCSIQTLGLISTAKPSFMNVPKSHFVSALTVVFVNSKSLSSIKIEDTPVDDPSLKILVANNSDTLRLLKMSSCPHVSSDGILCVADHCQGLRELALNYYILSDEILLALSSETHVNLEHLRIDVVSENPGQIKFHSIKKRSWDALIKHSPRVNVVMYFFLYEEEFEAFFKEETPVTHLYFGRSVSRAILGRIGLNCPRLIELVVCANGLLPLDSELIRIAKHCKNLTSLGLSECEVSCSAFVEFVRLCGRRLTQLSIMEEVLVPDDRYTPDEVHTEVSKHLGRVWFPDVMPIW", "length": 434 }, "evidence": [ { "id": "E1BUJ9", "url": "https://omabrowser.org/oma/group/E1BUJ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "E1BUJ9", "url": "https://www.uniprot.org/uniprotkb/E1BUJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BUJ9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 437, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BUJ9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BUJ9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 369, "end_pos": 371 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BUW2-1", "uniprot_ac": "E1BUW2", "uniprot_id": "E1BUW2_CHICK", "mass": { "chemical_mass": 21551.0, "monoisotopic_mass": 21551.0 }, "refseq": {}, "gene_names": [ { "name": "LHFPL1", "type": "recommended", "evidence": [ { "id": "E1BUW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUW2" } ] } ], "protein_names": [ { "name": "LHFPL tetraspan subfamily member 1", "type": "synonym", "evidence": [ { "id": "E1BUW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUW2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BUW2", "url": "https://www.uniprot.org/uniprotkb/E1BUW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LHFPL1", "url": "https://www.uniprot.org/uniprotkb/E1BUW2", "locus": {} } ], "crossref": [ { "id": "E1BUW2", "url": "https://alphafold.ebi.ac.uk/entry/E1BUW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017036", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017036", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418889", "url": "https://www.ncbi.nlm.nih.gov/gene/418889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418889", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418889", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWRICTV", "url": "https://omabrowser.org/oma/group/QWRICTV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BUW2", "url": "https://www.orthodb.org/?gene=E1BUW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BUW2", "url": "https://www.uniprot.org/uniprotkb/E1BUW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BUW2-1", "url": "https://www.uniprot.org/uniprotkb/E1BUW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSLTCAGMVWAFLSFLCAAASCVGFFMPYWLLGSQLEKSVSFGTFRRCSYPVRDESRQTTIMVEQCGRYASFQAIPSTEWRICTVVTGLGCGLLLLVALTALMGCCVSELISRTVGRVAGGIQFLGGLLIGSGCALYPLGWDSEEVRQTCGNLSNQFELGTCEIGWAYYCTGGGAAAAMLVCTWLACFSGKKQKQYPY", "length": 200, "header": "tr|E1BUW2-1|E1BUW2_CHICK Isoform 1 of LHFPL tetraspan subfamily member 1 OS=Gallus gallus OX=9031 GN=LHFPL1 PE=4 SV=3 CANONICAL=E1BUW2-1" }, "isoforms": [ { "isoform_ac": "E1BUW2-1", "url": "https://www.uniprot.org/uniprotkb/E1BUW2/entry#E1BUW2-1", "sequence": { "sequence": "MASSLTCAGMVWAFLSFLCAAASCVGFFMPYWLLGSQLEKSVSFGTFRRCSYPVRDESRQTTIMVEQCGRYASFQAIPSTEWRICTVVTGLGCGLLLLVALTALMGCCVSELISRTVGRVAGGIQFLGGLLIGSGCALYPLGWDSEEVRQTCGNLSNQFELGTCEIGWAYYCTGGGAAAAMLVCTWLACFSGKKQKQYPY", "length": 200, "header": "tr|E1BUW2-1|E1BUW2_CHICK Isoform 1 of LHFPL tetraspan subfamily member 1 OS=Gallus gallus OX=9031 GN=LHFPL1 PE=4 SV=3 CANONICAL=E1BUW2-1" }, "locus": { "chromosome": "1", "start_pos": 170984608, "end_pos": 170849263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010006255.1", "url": "https://www.ensembl.org/id/ENSGALT00010006255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003873.1", "url": "https://www.ensembl.org/id/ENSGALP00010003873.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418889", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418889", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LUK7-1", "protein_name": "LHFPL tetraspan subfamily member 6", "gene_name": "LHFPL6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSLTCTGVIWALLSFLCAATSCVGFFMPYWLWGSQLGKPVSFGTFRRCSYPVHDESRQMMVMVEECGRYASFQGIPSAEWRICTIVTGLGCGLLLLVALTALMGCCVSELISRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYISGQFDLGKCEIGWAYYCTGAGAAAAMLLCTWLACFSGKKQKQYPY", "length": 200 }, "evidence": [ { "id": "E1BUW2", "url": "https://omabrowser.org/oma/group/E1BUW2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5BJS2-1", "protein_name": "LHFPL tetraspan subfamily member 6 protein", "gene_name": "Lhfpl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSLTCTGVIWALLSFLSAATSCVGFFMPYWLWGSQLGKPVSFGTFRRCSYPVHDESRQMMVMVEECGRYASFQGIPSTEWRICTIVTGLGCGLLLLVALTALMGCCVSELISRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYISDQFDLGKCEIGWAYYCTGAGAAAAMLLCTWLACFSGKKQKHYPY", "length": 200 }, "evidence": [ { "id": "E1BUW2", "url": "https://omabrowser.org/oma/group/E1BUW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5PRC1-1", "protein_name": "LHFPL tetraspan subfamily member 6 protein", "gene_name": "lhfpl6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSLTCAGVIWALLSFLCAATSCVGFFMPYWLLGSQMGKPVSFGTFRRCSYPIRDEARGGTVMLEQCGRYASFQGIPSLEWRICTVVTGIGCGLLLLVALTAIMGCCVTDLISRTIGRVAGGIQFVGGLLIGSGCALYPLGWDSEEVRQTCSNSSDQFDLGSCEIGWAYYCTGAGAAAAMVLCTWMACFAGKKQKHYPY", "length": 200 }, "evidence": [ { "id": "E1BUW2", "url": "https://omabrowser.org/oma/group/E1BUW2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BM86-1", "protein_name": "LHFPL tetraspan subfamily member 6 protein", "gene_name": "Lhfpl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSLTCTGVIWALLSFLSAATSCVGFFMPYWLWGSQLGKPVSFGTFRRCSYPVHDESRQMMVMVEECGRYASFQGIPSTEWRICTIVTGLGCGLLLLVALTALMGCCVSELISRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYISGQFDLGKCEIGWAYYCTGAGAAAAMLLCTWMACFSGKKQKHYPY", "length": 200 }, "evidence": [ { "id": "E1BUW2", "url": "https://omabrowser.org/oma/group/E1BUW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y693-1", "protein_name": "LHFPL tetraspan subfamily member 6 protein", "gene_name": "LHFPL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSLTCTGVIWALLSFLCAATSCVGFFMPYWLWGSQLGKPVSFGTFRRCSYPVHDESRQMMVMVEECGRYASFQGIPSAEWRICTIVTGLGCGLLLLVALTALMGCCVSDLISRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYTSGQFDLGKCEIGWAYYCTGAGATAAMLLCTWLACFSGKKQKHYPY", "length": 200 }, "evidence": [ { "id": "E1BUW2", "url": "https://omabrowser.org/oma/group/E1BUW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BUW2", "url": "https://www.uniprot.org/uniprotkb/E1BUW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BUW2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 200, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BUW2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BUW2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BV81-1", "uniprot_ac": "E1BV81", "uniprot_id": "E1BV81_CHICK", "mass": { "chemical_mass": 13666.0, "monoisotopic_mass": 13666.0 }, "refseq": { "ac": "XP_003641167", "name": "SH2 domain-containing protein 1A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641167" }, "gene_names": [ { "name": "SH2D1A", "type": "recommended", "evidence": [ { "id": "E1BV81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ] }, { "name": "SH2D1A", "type": "synonym", "evidence": [ { "id": "XP_003641167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641167" } ] } ], "protein_names": [ { "name": "SH2 domain containing 1A", "type": "synonym", "evidence": [ { "id": "E1BV81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BV81/entry#names_and_taxonomy" } ] }, { "name": "SH2 domain-containing protein 1A", "type": "synonym", "evidence": [ { "id": "XP_003641167", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641167" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641167" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH2D1A", "url": "https://www.uniprot.org/uniprotkb/E1BV81", "locus": { "chromosome": "4", "start_pos": 15485701, "end_pos": 15501642, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013213", "url": "https://www.ensembl.org/id/ENSGALG00010013213" } ] } } ], "crossref": [ { "id": "E1BV81", "url": "https://alphafold.ebi.ac.uk/entry/E1BV81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008447", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008447", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10400", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10400", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100857869", "url": "https://www.ncbi.nlm.nih.gov/gene/100857869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857869", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSPGRNE", "url": "https://omabrowser.org/oma/group/YSPGRNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46051:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46051:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641167", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BV81-1", "url": "https://www.uniprot.org/uniprotkb/E1BV81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALPIYHGGITREAGEKLLLAAGADGSYLLRDSESIPGVYCLCVLHQGYVYTYRVSKTESGSWSAETAPGVHRRLFRKMHNLISAFQKPDQGIVTPLKHPVINCAKAKYSPGRSDGRDYLQPS", "length": 124, "header": "tr|E1BV81-1|E1BV81_CHICK Isoform 1 of SH2 domain containing 1A OS=Gallus gallus OX=9031 GN=SH2D1A PE=1 SV=4 CANONICAL=E1BV81-1" }, "isoforms": [ { "isoform_ac": "E1BV81-1", "url": "https://www.uniprot.org/uniprotkb/E1BV81/entry#E1BV81-1", "sequence": { "sequence": "MEALPIYHGGITREAGEKLLLAAGADGSYLLRDSESIPGVYCLCVLHQGYVYTYRVSKTESGSWSAETAPGVHRRLFRKMHNLISAFQKPDQGIVTPLKHPVINCAKAKYSPGRSDGRDYLQPS", "length": 124, "header": "tr|E1BV81-1|E1BV81_CHICK Isoform 1 of SH2 domain containing 1A OS=Gallus gallus OX=9031 GN=SH2D1A PE=1 SV=4 CANONICAL=E1BV81-1" }, "locus": { "chromosome": "4", "start_pos": 15501592, "end_pos": 15488560, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031725.1", "url": "https://www.ensembl.org/id/ENSGALT00010031725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018572.1", "url": "https://www.ensembl.org/id/ENSGALP00010018572.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857869", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W811-1", "protein_name": "SH2 domain-containing protein 1A", "gene_name": "SH2D1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGATGRREDPDVFLKTP", "length": 128 }, "evidence": [ { "id": "E1BV81", "url": "https://omabrowser.org/oma/group/E1BV81/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LVA5-1", "protein_name": "SH2 domain-containing protein 1A", "gene_name": "Sh2d1a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKIKNLISAFQKPDQGIVIPLQYPVEKSSARSTQGTTGRSDSDVCLKAP", "length": 126 }, "evidence": [ { "id": "E1BV81", "url": "https://omabrowser.org/oma/group/E1BV81/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E7F0N7-1", "protein_name": "SH2 domain-containing protein 1A", "gene_name": "sh2d1ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESLSVYHGAISREMCEMRLNEAGKDGSYLIRDSESVAGAYCLCVLCKGFVYTYRLQKDSAGSWAAETAPGQTKRLFRKVKNLISAFEKPGQGIAIPLLYPVTIQKSY", "length": 108 }, "evidence": [ { "id": "E1BV81", "url": "https://omabrowser.org/oma/group/E1BV81/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60880-1", "protein_name": "SH2 domain-containing protein 1A", "gene_name": "SH2D1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIREDPDVCLKAP", "length": 128 }, "evidence": [ { "id": "E1BV81", "url": "https://omabrowser.org/oma/group/E1BV81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88890-1", "protein_name": "SH2 domain-containing protein 1A", "gene_name": "Sh2d1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAVTVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKVKNLISAFQKPDQGIVTPLQYPVEKSSGRGPQAPTGRRDSDICLNAP", "length": 126 }, "evidence": [ { "id": "E1BV81", "url": "https://omabrowser.org/oma/group/E1BV81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZBB1-1", "protein_name": "SH2 domain-containing protein 1A", "gene_name": "SH2D1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKIKNLISAFQKPDQGIVIPLQYPVEKKPSARSTQGATGRRDDPDVFLKTP", "length": 128 }, "evidence": [ { "id": "E1BV81", "url": "https://omabrowser.org/oma/group/E1BV81/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ], "pmid": "" }, { "name": "natural killer cell activation", "id": "GO:0030101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030101", "evidence": [ { "database": "UniProtKB", "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ], "pmid": "" }, { "name": "negative regulation of T cell receptor signaling pathway", "id": "GO:0050860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050860", "evidence": [ { "database": "UniProtKB", "id": "E1BV81", "url": "https://www.uniprot.org/uniprotkb/E1BV81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BV81-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 124, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BV81-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BV81" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BV83-1", "uniprot_ac": "E1BV83", "uniprot_id": "E1BV83_CHICK", "mass": { "chemical_mass": 228331.0, "monoisotopic_mass": 228331.0 }, "refseq": { "ac": "XP_416176", "name": "nuclear pore complex protein Nup205 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416176" }, "gene_names": [ { "name": "NUP205", "type": "recommended", "evidence": [ { "id": "E1BV83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ] }, { "name": "NUP205", "type": "synonym", "evidence": [ { "id": "XP_416176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416176" } ] } ], "protein_names": [ { "name": "Nucleoporin 205", "type": "synonym", "evidence": [ { "id": "E1BV83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BV83/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup205 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416176" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_416176.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416176" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NUP205", "url": "https://www.uniprot.org/uniprotkb/E1BV83", "locus": { "chromosome": "1", "start_pos": 47756781, "end_pos": 47802414, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011702", "url": "https://www.ensembl.org/id/ENSGALG00010011702" } ] } } ], "crossref": [ { "id": "ENSGALG00000011662", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011662", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417935", "url": "https://www.ncbi.nlm.nih.gov/gene/417935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417935", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417935", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSQMFAE", "url": "https://omabrowser.org/oma/group/WSQMFAE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BV83", "url": "https://www.orthodb.org/?gene=E1BV83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31344:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31344:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855170", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855196", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855229", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-191859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3232142", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3301854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4085377", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4615885", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9615933", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9615933", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_416176", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416176", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BV83-1", "url": "https://www.uniprot.org/uniprotkb/E1BV83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPLAVNSAASLWGPYKDIWQTVMNAIWKRQPEAIHRLDQVLKKHRSDFISLFRNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIREAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLRTLIQSRQGKTWTLELSQELVSMTTRFTDDLMEQGLTQKILTLVSQIDLNNEFDKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFVWTCQSPLSKDDTLILISYLEKVTVEADGSLDSVNLSLLMALLYCFDVSFLEQGTEDREDLMHRLPLLAERQYIATIHTRLQESQPWKLPGLQATVRLAWALALRGISQLSDVTALAEFTEADEAMAELAVADNVFLFLTESVVGSENFYQEEFYIRKIHNLVTDFLALMPMKVKQLRNRADEDARMIHMSIQMGNDPPISLRRDLEHLMLLIAELYRKDPFNLELALEYWCPSEPLQTSTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPSTIYIPYLKMLRGLASGPQCAHYCFSLLKVNGSSHAENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPLRGITQKEQDGLIAFLQLTTVIVNWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLETLTAFGKSPEIAASLWQSLEYTQILQTVRTPGQRQAIGIEVELNEIESRCEEYPLTRAFCRLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQYVELQGDEIIAYKPPGFNLMYHLLNESPMLELSLSLLEEGVKQLDTYAPFPGKKHLEKAVEHCLALLNLTLQKENLFMDLLRESHLSLIVTPLEQLLQGINPRTKKADHVVNIARYLYHGNSNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSTSQKLMAGFVECLDNEDAEELINPDEELEPEKKRARIHHETRIHILNLLITSLECSPPSLALYLLGYELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTETRNGPTAVQESPHLAELCYQVIYQLCACSETSGPTMRYLRTSQDFLFTQLQYLPFSIREHEISTLNQMSWLMKTAAIEMRVTSLNRQRSHTQRLLHLLLDDMPVKPYLADGEGGMEDESRSVSGFLHFDTASKVRRKILSILDSIDFSQDIPEPLQLDFFDRVQIEQVIANCEHKNARGQVVCNVKHLHRVLVAEVNALQGMAAIGQRPLLMEEINTILQYVVERNKLLQCLHAKKHALESWRQLVEIILTACPQDLIQAEDRQLIIRDLLQDVHDKILDDDAAQELMPVVAGAVFTLTAHLSQSVKTEQKQPLAVPMTGQSQYVLMLDGSFTSSPGSESISMGFASIGDSSLHIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENMAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVDDDLTLQSLLMPQPPLLKALYTYESKMAFLTRVAKSQQGALELLRSGVIVRLAQCQVYDMRPETDHQGMYGMRDPPVFIPAPVERYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSVGSLQELASLTGIISKAALPGVLNELDVDVNEGTQMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKLQDDNAEGDRVNKRDEIELAMQQICANVMEYCESLMLQSAPSFEHTVCLFTPSLSESTNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSTNDFFSYYDSHRQSVNKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKLINNRAKLLSLCSYIIETCLFILWRHLEHYLLNYTPTDSQDSLLSSRISFKRGRLQDSFGSESSLDFSSGLNRVSQHDIDQLQIETTNSFGESLQKKLLDIEGLYSKVRSRYTFIQALVRRIRGLLRISRT", "length": 2014, "header": "tr|E1BV83-1|E1BV83_CHICK Isoform 1 of Nucleoporin 205 OS=Gallus gallus OX=9031 GN=NUP205 PE=1 SV=2 CANONICAL=E1BV83-1" }, "isoforms": [ { "isoform_ac": "E1BV83-1", "url": "https://www.uniprot.org/uniprotkb/E1BV83/entry#E1BV83-1", "sequence": { "sequence": "MAAPLAVNSAASLWGPYKDIWQTVMNAIWKRQPEAIHRLDQVLKKHRSDFISLFRNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIREAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLRTLIQSRQGKTWTLELSQELVSMTTRFTDDLMEQGLTQKILTLVSQIDLNNEFDKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFVWTCQSPLSKDDTLILISYLEKVTVEADGSLDSVNLSLLMALLYCFDVSFLEQGTEDREDLMHRLPLLAERQYIATIHTRLQESQPWKLPGLQATVRLAWALALRGISQLSDVTALAEFTEADEAMAELAVADNVFLFLTESVVGSENFYQEEFYIRKIHNLVTDFLALMPMKVKQLRNRADEDARMIHMSIQMGNDPPISLRRDLEHLMLLIAELYRKDPFNLELALEYWCPSEPLQTSTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPSTIYIPYLKMLRGLASGPQCAHYCFSLLKVNGSSHAENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPLRGITQKEQDGLIAFLQLTTVIVNWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLETLTAFGKSPEIAASLWQSLEYTQILQTVRTPGQRQAIGIEVELNEIESRCEEYPLTRAFCRLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQYVELQGDEIIAYKPPGFNLMYHLLNESPMLELSLSLLEEGVKQLDTYAPFPGKKHLEKAVEHCLALLNLTLQKENLFMDLLRESHLSLIVTPLEQLLQGINPRTKKADHVVNIARYLYHGNSNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSTSQKLMAGFVECLDNEDAEELINPDEELEPEKKRARIHHETRIHILNLLITSLECSPPSLALYLLGYELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTETRNGPTAVQESPHLAELCYQVIYQLCACSETSGPTMRYLRTSQDFLFTQLQYLPFSIREHEISTLNQMSWLMKTAAIEMRVTSLNRQRSHTQRLLHLLLDDMPVKPYLADGEGGMEDESRSVSGFLHFDTASKVRRKILSILDSIDFSQDIPEPLQLDFFDRVQIEQVIANCEHKNARGQVVCNVKHLHRVLVAEVNALQGMAAIGQRPLLMEEINTILQYVVERNKLLQCLHAKKHALESWRQLVEIILTACPQDLIQAEDRQLIIRDLLQDVHDKILDDDAAQELMPVVAGAVFTLTAHLSQSVKTEQKQPLAVPMTGQSQYVLMLDGSFTSSPGSESISMGFASIGDSSLHIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENMAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVDDDLTLQSLLMPQPPLLKALYTYESKMAFLTRVAKSQQGALELLRSGVIVRLAQCQVYDMRPETDHQGMYGMRDPPVFIPAPVERYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSVGSLQELASLTGIISKAALPGVLNELDVDVNEGTQMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKLQDDNAEGDRVNKRDEIELAMQQICANVMEYCESLMLQSAPSFEHTVCLFTPSLSESTNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSTNDFFSYYDSHRQSVNKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKLINNRAKLLSLCSYIIETCLFILWRHLEHYLLNYTPTDSQDSLLSSRISFKRGRLQDSFGSESSLDFSSGLNRVSQHDIDQLQIETTNSFGESLQKKLLDIEGLYSKVRSRYTFIQALVRRIRGLLRISRT", "length": 2014, "header": "tr|E1BV83-1|E1BV83_CHICK Isoform 1 of Nucleoporin 205 OS=Gallus gallus OX=9031 GN=NUP205 PE=1 SV=2 CANONICAL=E1BV83-1" }, "locus": { "chromosome": "1", "start_pos": 47802110, "end_pos": 47756989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028003.1", "url": "https://www.ensembl.org/id/ENSGALT00010028003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016061.1", "url": "https://www.ensembl.org/id/ENSGALP00010016061.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417935", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417935", "resource": "KEGG Pathway" }, { "id": "R-GGA-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-GGA-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-GGA-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-GGA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-GGA-1855170", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855170", "resource": "Reactome", "description": "IPs transport between nucleus and cytosol" }, { "id": "R-GGA-1855196", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855196", "resource": "Reactome", "description": "IP3 and IP4 transport between cytosol and nucleus" }, { "id": "R-GGA-1855229", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855229", "resource": "Reactome", "description": "IP6 and IP7 transport between cytosol and nucleus" }, { "id": "R-GGA-191859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-191859", "resource": "Reactome", "description": "snRNP Assembly" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3232142", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3232142", "resource": "Reactome", "description": "SUMOylation of ubiquitinylation proteins" }, { "id": "R-GGA-3301854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3301854", "resource": "Reactome", "description": "Nuclear Pore Complex (NPC) Disassembly" }, { "id": "R-GGA-4085377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085377", "resource": "Reactome", "description": "SUMOylation of SUMOylation proteins" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4615885", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4615885", "resource": "Reactome", "description": "SUMOylation of DNA replication proteins" }, { "id": "R-GGA-9615933", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9615933", "resource": "Reactome", "description": "Postmitotic nuclear pore complex (NPC) reformation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BQ98-1", "protein_name": "Nucleoporin 205", "gene_name": "NUP205", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATLLAVNSAASLWGPYKDIWQTVGNALWRRQPEAVHLLDMILKKHKPDFISLFRNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELVSMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKDDTLLLIGHLERVSVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTERQYIATVHSRLQDSQPWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAVADNVFLFLTEAVVVSENFYQEEFYIRRIHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFNLELALEYWCPSEPLQTSTILGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRVPSQRQAIGIEVELNEIESRCEEYPLTRAFCHLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVSPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQRLMAGFVECLDSEDMEEFVRLEEGSELEKKLAGIRHETRIHILNLLITSLERNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQHLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGLEDENRSVSGFLHFDTATKVRRKILSILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTILQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVRTEQKQPLVLGPGEAHYAFMLDSSFTSPPPAENPVVGFASIGDSSLHIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPEMDPQGMFGMRDPPVFIPTPVDRYRQILLPALRLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDRVSKKDEVELAMQQICANVMEYCQSLMLQSSPTFQHGVCLFTPSLSETSNRDGPRQDTQAPVVPYWRLPGLGIIVYLLKQSANDFFSYYDSHRRSVNKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKLINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCTPTDSQESLFASRTLFKSRRLQDSFTSESNLDFRSGLTIVSQHDLDQLQADTINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRVRGLLRISRN", "length": 2012 }, "evidence": [ { "id": "E1BV83", "url": "https://omabrowser.org/oma/group/E1BV83/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZJ67-1", "protein_name": "Nucleoporin 205", "gene_name": "Nup205", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGAATALPWRRVFEGEAERRSPGRPGARSGSRSVPEVSFRCRQANFHQAASLWGPYKDIWQTVGNALWRRQPEAVHLLDMILKKHKPDFISLFKNPPKNVQQHEKIQKASSEGVAIQGQQGTRLLPEQLIKEAFIISDLFDIGELSAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKTLIQSRRGKTWTLELSPELVSMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRDRGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLAKDDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDTSFIEQSTEERDDMIHHLPLLTERQYIATIHSRLQDSQPWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAIAELAIADNVFLFLSESVVLAENFYQEEFYIRRIHNLITDFLAFMPMKVKQLKNRADEDARMIHMSIQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPSEPLQTPTVMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLLLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPALKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRVPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVSPLEQLLQGINPRTKKADNVVNIARYLYHGNSNPELAFESAKILCCISCNSNIQIKMVGDFTHDQNVSQKLMAGFVECLDSEDTEEFVRVEEGSELEKKLAAIRHETRIHILNLLITSLERSPPNLALYLLGFELKKPISTTNLQDPGVLGCPRTCLHAILNILEKGTDGRSGPVAVQACPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQHLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDLPVKPYSDGEGGMEDENRSVSGFLHFDTATKVRRKILSILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLQGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTILQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQELIQAEDRQLIIRDILQDVHDKVLDDEAAQELMPVVAGAVFTLTAHLSQAVRTEQKQPLVSGPAEAHYAFMLDSSFTSAPAAESQPVGFASIGDSSLHIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENMAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLLEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKLQQGSLELLRSGVIVRLAQCQVYDMRPEVDSHSMFGMRDPPIFIPTPVDRYRQILLPALQLCQVILTSSMSQHLQAAGQVLQFLVSHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGMLNELDVDVNEGSLMELQGHIARFQRQCLGLLSRFGGSDRLRQFKLQEDNVEGDRLSKKDEIELAMQQICANVMEYCHSFMQQNSPNLQNAVCLFTPSLSETVNRDGARQDTQVPVVPYWRLPGLGIIIYLLKQSASDFFSYYDSHRRSVNKLQNVEQLPPDEIKELCQSVMPAGIDKISTAQKCVLARRRLVKLINNRAKLLSLCSYIIETCLFILWRHLEYYLLHCTPMDSQDSLFASRTLLKSRRLQEPNLDFSRSGLAQVNQHDIDQLQSDAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN", "length": 2049 }, "evidence": [ { "id": "E1BV83", "url": "https://omabrowser.org/oma/group/E1BV83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IQV9-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "Nup205", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDGECLANEQMCVGRQITNATHASTAVIEDMWTPYKHLYNTFQTAVSNRSGFTSDLEQCLKKYKHNFSNLLRNPPRSEKSRNLLRNALNEGVPMQGHSRKTKMSQDLADEAVILSDMFDLDEGFAVELLCTAQRQQKHHPGLSRGLVAVLLYYDGRKAISCTLRDMFQVVSGVSWNTELPKEITGLVTNYAESLVDGSGILGRLLQLLEEMDVDKECAMLTTNRAFGSKKHQNQVLGLYEDIQQALAMALFNWSAQRGLPRHIAIRLMHQLANRKNHDAGGNMDDVTLIMLMALLYAYDTSMLLVTEEPNEHTTRLPIFSDREFAECFLEELYAQSSWQAPRLNAIIAYSFGLTLASLRHAPLQLQATAISIINRDEMLIDEALGAQVFVFFHSLLLEKDLVYSTQFFYRRVHLLITDFIDFMNSKVSELRGRADESSHTIISFLNEGLEPPPNLDSNFELLMLCVAKMHGDPRVTIRLCNEYWGPGDPNGSTAFKNTSRSVSLFKFISLASDLLPQTLFKAYLKMISGLTRTDFSARCAFNMLRVPQMATGGKYAVSWDHFFTTLGNYYTSMRNDFNTNIGMSGETIYRTRSTPKAITQREAEHLVAVMGIIQAVAEHDEVSRIMICDHPNWQTPQVLLGLVACATPLFLKAEILHTLAALAKSKETARVIWFHLEASQIIPTVPVSRSYAQCSLLEEMEQIESRSEQYNLTRGILQLLYTLMTTNLPKSLGAGQRTPAYEGYLKSMINSVLLKFYNRAYKVPSEKWQVGAQCLKLLYYLLATYRPSAMDFLETVDEPPYPGFHVMMQLQLKSEMLQLLLCIVEEVRERLDNYNRFQGKKLLEECSLYALLILEAALAKQNAFFEAHSAANCPILLSGLNRMLLDLNPRSRKPDHVLNIIKYVTYNSWLPRHALAAIKILASVTQLPNVSTQILSMYGQGSNEKLEIRQGFVECLEMEVCVGKHDDDLLDQLALNNHVPYLGFGDDLDNEREMSGEREYSTIESQLELQAGDGALESKPASIELQLKEAIIKLFEMNLSQQLPNFVYFLLGVDVLREFMANGRQHLAIEMQSSCVNSVVLLLEKYMDKQRHSDKYCEHTARIVERIYHLFHGLCANRRTAETILRYFRLTCSDFLLRHLRSLPFRQHREDHVLHAMGHLLNCVSIDVKLAAKHGQMTRFNQMCDILLIGNGMERSSHGLSMELGHSLISQPSSSFLAMDVLPAGGSISAVAHGAGSASLGAPNTGVKSLKPSLLQETSQGLHVTRLLDILVLEAGTLSQPQLEFFDGHLITQLLRDCEASAEAGANSRANLINVRKLYYILTDELYMVQSIIASGQRKAISTEIMLLLNHAVNINRVRTQRCATLAFMAAWGQLVQVLFSNMPDAVLPATQRRQHIIDIVEKVLIKVQPIQPIIEISVQVSETVLLLLANLRYCCYQAEDQSPEDLAAEDSLSNGNGNAIGNDSQVNALCLGQRAIGTGSDGGSGGGRDIGSGGNSSNLRFILKNLVQWIMISEVKSQKLRINLYSSLLNCLRIAKRLRTDEHLEYQETLISRQESARTYNKEQRRDDRLRLKAMAAEVIGTFGEKLIDTICHDAVTGHDVCRMLALACLDMISELQAVSTLCDFVASRGYLKHILESLDQSSTALCGILQPVPDHLRPLYVYESRMAFLTRMANSNVGARLLLTEQALGVLSNMKVYDQQPDLKSSELNRNEPQTFLPSIDDRFRSILLPALSLCDAIVNSLGPRNNSAAVQVLNFLFAHIDMVEAMLRSATPYMDLGHLQQVAVISNLFARASTHELTALEDSVQLDLRNRLGRVQQLMIVVFGRFCVSEPTIRRMLQQDEEQQTNPTDDSKRLRVKYFLDIAANVSLYCRNVVTSHSKDSMTSKYLLTTVINDVTLLTGKMSSKKLTTIMHTILNQLKGSIGYYLSQKSIADNLLQQRASLPNISFGPNGKQSYIELSQRYNEKRSELRQAVFIAEQNLYLLWIHLDFYLRNTIDYANENRNAINESNMDDDNDMSVLNASQEEIVQLKQLLISTFNETFCTQLINASEDYSIKCKGFNGSLLRRIKALVQFAPITANDVNSSFDS", "length": 2090 }, "evidence": [ { "id": "E1BV83", "url": "https://omabrowser.org/oma/group/E1BV83/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDAEEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDSQDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN", "length": 2012 }, "evidence": [ { "id": "E1BV83", "url": "https://omabrowser.org/oma/group/E1BV83/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ], "pmid": "" }, { "name": "nuclear pore complex assembly", "id": "GO:0051292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051292", "evidence": [ { "database": "UniProtKB", "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ], "pmid": "" }, { "name": "nuclear periphery", "id": "GO:0034399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034399", "evidence": [ { "database": "UniProtKB", "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ], "pmid": "" }, { "name": "nuclear pore inner ring", "id": "GO:0044611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044611", "evidence": [ { "database": "UniProtKB", "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "E1BV83", "url": "https://www.uniprot.org/uniprotkb/E1BV83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1916, "end_pos": 1918, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" }, { "start_pos": 854, "end_pos": 856, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1916, "end_pos": 1918 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 811, "end_pos": 813 }, { "start_pos": 854, "end_pos": 856 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", 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"https://www.uniprot.org/uniprotkb/E1BV97", "locus": { "chromosome": "11", "start_pos": 545755, "end_pos": 554536, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022241", "url": "https://www.ensembl.org/id/ENSGALG00010022241" } ] } } ], "crossref": [ { "id": "E1BV97", "url": "https://alphafold.ebi.ac.uk/entry/E1BV97", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001168", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07031", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07031", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMI7", "url": "https://www.orthodb.org/?gene=A0A8V0ZMI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPA1", "url": "https://www.orthodb.org/?gene=A0A8V0ZPA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BV97", "url": "https://www.orthodb.org/?gene=E1BV97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11800:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11800:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-76042", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-76042", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-77075", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77075", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZMI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BV97", "url": "https://www.uniprot.org/uniprotkb/E1BV97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BV97-1", "url": "https://www.uniprot.org/uniprotkb/E1BV97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKMQYSRDCTCDEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNNPRVIPVTSRSRDNDPNDYVEQDDILIVKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSEIDEEDAQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN", "length": 275, "header": "tr|E1BV97-1|E1BV97_CHICK Isoform 1 of DNA-directed RNA polymerase II subunit RPB3 OS=Gallus gallus OX=9031 GN=POLR2C PE=1 SV=1 CANONICAL=E1BV97-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMI7-1", "url": "https://www.uniprot.org/uniprotkb/E1BV97/entry#A0A8V0ZMI7-1", "sequence": { "sequence": "MGRPFPAAPIKPRTVTSPRLSCASPAAGVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKMQYSRDCTCDEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNNPRVIPVTSRSRDNDPNDYVEQDDILIVKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSEIDEEDAQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN", "length": 274, "header": "tr|A0A8V0ZMI7-1|A0A8V0ZMI7_CHICK Computationally mapped isoform of DNA-directed RNA polymerase II subunit RPB3 OS=Gallus gallus OX=9031 GN=POLR2C PE=1 SV=1 CANONICAL=E1BV97-1" }, "locus": { "chromosome": "11", "start_pos": 554506, "end_pos": 547329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054137.1", "url": "https://www.ensembl.org/id/ENSGALT00010054137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032668.1", "url": "https://www.ensembl.org/id/ENSGALP00010032668.1" } ] } }, { "isoform_ac": "A0A8V0ZPA1-1", "url": "https://www.uniprot.org/uniprotkb/E1BV97/entry#A0A8V0ZPA1-1", "sequence": { "sequence": "MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKMQYSRDCTCDEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNNPRVIPVTSRSRDNDPNDYVEQDDILIVKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN", "length": 250, "header": "tr|A0A8V0ZPA1-1|A0A8V0ZPA1_CHICK Computationally mapped isoform of DNA-directed RNA polymerase II subunit RPB3 OS=Gallus gallus OX=9031 GN=POLR2C PE=1 SV=1 CANONICAL=E1BV97-1" }, "locus": { "chromosome": "11", "start_pos": 554315, "end_pos": 547329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054117.1", "url": "https://www.ensembl.org/id/ENSGALT00010054117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032648.1", "url": "https://www.ensembl.org/id/ENSGALP00010032648.1" } ] } }, { "isoform_ac": "E1BV97-1", "url": "https://www.uniprot.org/uniprotkb/E1BV97/entry#E1BV97-1", "sequence": { "sequence": "MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLTSDDIVDKMQYSRDCTCDEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNNPRVIPVTSRSRDNDPNDYVEQDDILIVKLRKGQELKLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSEIDEEDAQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN", "length": 275, "header": "tr|E1BV97-1|E1BV97_CHICK Isoform 1 of DNA-directed RNA polymerase II subunit RPB3 OS=Gallus gallus OX=9031 GN=POLR2C PE=1 SV=1 CANONICAL=E1BV97-1" }, "locus": { "chromosome": "11", "start_pos": 554315, "end_pos": 547329, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054124.1", "url": "https://www.ensembl.org/id/ENSGALT00010054124.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032655.1", "url": "https://www.ensembl.org/id/ENSGALP00010032655.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-6781823", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781823", "resource": "Reactome", "description": "Formation of TC-NER Pre-Incision Complex" }, { "id": "R-GGA-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-GGA-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-GGA-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-GGA-72086", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72086", "resource": "Reactome", "description": "mRNA Capping" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-GGA-73776", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73776", "resource": "Reactome", "description": "RNA Polymerase II Promoter Escape" }, { "id": "R-GGA-73779", "name": "", "url": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1BV97", "url": "https://www.uniprot.org/uniprotkb/E1BV97" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "E1BV97", "url": "https://www.uniprot.org/uniprotkb/E1BV97" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "E1BV97", "url": "https://www.uniprot.org/uniprotkb/E1BV97" } ], "pmid": "" } ] }, { "name": "Biological Process", 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"https://www.uniprot.org/uniprotkb/E1BV97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "E1BV97", "url": "https://www.uniprot.org/uniprotkb/E1BV97" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BV97", "url": "https://www.uniprot.org/uniprotkb/E1BV97" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase complex", "id": "GO:0000428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000428", "evidence": [ { "database": "UniProtKB", "id": "E1BV97", "url": "https://www.uniprot.org/uniprotkb/E1BV97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420944", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420944", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EKCHCEA", "url": "https://omabrowser.org/oma/group/EKCHCEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TT95", "url": "https://www.orthodb.org/?gene=A0A3Q2TT95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVA8", "url": "https://www.orthodb.org/?gene=E1BVA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46252:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46252:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23331", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23331", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23333", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23333", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TT95", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TT95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TT95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVA8-1", "url": "https://www.uniprot.org/uniprotkb/E1BVA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSSTAMAIGALSSSLLVTCCLMVALCSSTIPLQKLARAQDKQEIKASQEKRDHASARDSQAGAGKVGEIGRSGREEGGRDWKGKGGRNYSSKESWTKQKQAWSSQGTGGKPASVPAQEQQDMAAEAPRPAEASSLPAAVASATPEPLEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCMQPECPRLHPRCVHVDTTQCCPQCKERKNYCEFRGKTYQSLEEFMVSPCEKCRCEASGEVLCTVSACPQTECVDPVYEPDQCCPICKNGTCAYAKSGAGCRENRHNSIECSCGFVEGEEEEKLQRVSGKVVKVTDTVASVGPNCFAETTVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECKQI", "length": 383, "header": "tr|E1BVA8-1|E1BVA8_CHICK Isoform 1 of von Willebrand factor C domain containing 2 OS=Gallus gallus OX=9031 GN=VWC2 PE=4 SV=3 CANONICAL=E1BVA8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TT95-1", "url": "https://www.uniprot.org/uniprotkb/E1BVA8/entry#A0A3Q2TT95-1", "sequence": { "sequence": "MPSSTAMAIGALSSSLLVTCCLMVALCSSTIPLQKLARAQDKQEIKASQEKRDHASARDSQAGAGKVGEIGRSGREEGGRDWKGKGGRNYSSKESWTKQKQAWSSQGTGGKPASVPAQEQQDMAAEAPRPAEASSLPAAVASATPEPLEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCMQPECPRLHPRCVHVDTTQCCPQCKERKNYCEFRGKTYQSLEEFMVSPCEKCRCEASGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETTVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECKQI", "length": 331, "header": "tr|A0A3Q2TT95-1|A0A3Q2TT95_CHICK Computationally mapped isoform of von Willebrand factor C domain containing 2 OS=Gallus gallus OX=9031 GN=VWC2 PE=4 SV=1 CANONICAL=E1BVA8-1" }, "locus": { "chromosome": "2", "start_pos": 80169929, "end_pos": 80112881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001333.1", "url": "https://www.ensembl.org/id/ENSGALT00010001333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000704.1", "url": "https://www.ensembl.org/id/ENSGALP00010000704.1" } ] } }, { "isoform_ac": "E1BVA8-1", "url": "https://www.uniprot.org/uniprotkb/E1BVA8/entry#E1BVA8-1", "sequence": { "sequence": "MPSSTAMAIGALSSSLLVTCCLMVALCSSTIPLQKLARAQDKQEIKASQEKRDHASARDSQAGAGKVGEIGRSGREEGGRDWKGKGGRNYSSKESWTKQKQAWSSQGTGGKPASVPAQEQQDMAAEAPRPAEASSLPAAVASATPEPLEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCMQPECPRLHPRCVHVDTTQCCPQCKERKNYCEFRGKTYQSLEEFMVSPCEKCRCEASGEVLCTVSACPQTECVDPVYEPDQCCPICKNGTCAYAKSGAGCRENRHNSIECSCGFVEGEEEEKLQRVSGKVVKVTDTVASVGPNCFAETTVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECKQI", "length": 383, "header": "tr|E1BVA8-1|E1BVA8_CHICK Isoform 1 of von Willebrand factor C domain containing 2 OS=Gallus gallus OX=9031 GN=VWC2 PE=4 SV=3 CANONICAL=E1BVA8-1" }, "locus": { "chromosome": "2", "start_pos": 80169929, "end_pos": 80112881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001331.1", "url": "https://www.ensembl.org/id/ENSGALT00010001331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000702.1", "url": "https://www.ensembl.org/id/ENSGALP00010000702.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420944", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420944", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BE14-1", "protein_name": "von Willebrand factor C domain containing 2", "gene_name": "VWC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSSTAMAVGALSSSLLLTCCLMVALCSPRIPLEKLAQAPERPGQEKREHASRDGPGRVSELGRPARDEGGGGGRDWKGKSGRGLAGREAWSRQKQAWAAQGGGAGAGDLQGRPRGDTPHEEPPAAAAQDVAGPESEPTPEPPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEASGEVLCAVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 326 }, "evidence": [ { "id": "E1BVA8", "url": "https://omabrowser.org/oma/group/E1BVA8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SF29-1", "protein_name": "von Willebrand factor C domain containing 2", "gene_name": "VWC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSSTAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDGPGRVSELGRPARDEGGGGRDWKGKGGRGLTSREAWSRQKQAWPAQGGGAKAGDLQVRPRGDTPHEEPPAASAQDAAGSDPGPTLEPPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEASGEVLCAVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 325 }, "evidence": [ { "id": "E1BVA8", "url": "https://omabrowser.org/oma/group/E1BVA8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RB53-1", "protein_name": "von Willebrand factor C domain containing 2", "gene_name": "Vwc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSSSAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDSPGRVSELGRASRDEGSSARDWKSKGSRALSGREAWSKQKQAWAAQSGSAKAADWQVRPRGDTPQGEPPAAAQEAISLELMPTPELPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 324 }, "evidence": [ { "id": "E1BVA8", "url": "https://omabrowser.org/oma/group/E1BVA8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2TAL6-1", "protein_name": "Brorin", "gene_name": "VWC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSTAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDGPGRVNELGRPARDEGGSGRDWKSKSGRGLAGREPWSKLKQAWVSQGGGAKAGDLQVRPRGDTPQAEALAAAAQDAIGPELAPTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 325 }, "evidence": [ { "id": "E1BVA8", "url": "https://omabrowser.org/oma/group/E1BVA8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C8N3-1", "protein_name": "Brorin", "gene_name": "Vwc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSSSAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHASRDSPGRVSELGRASRDEGSSARDWKSKGSRALSGREAWSKQKQAWAAQGGSAKAADWQVRPRGDTPQGEPPAAAQEAISLELVPTPELPEEYAYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDNSQCCPQCKEKKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQM", "length": 324 }, "evidence": [ { "id": "E1BVA8", "url": "https://omabrowser.org/oma/group/E1BVA8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "extrinsic component of postsynaptic membrane", "id": "GO:0098890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098890", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "E1BVA8", "url": "https://www.uniprot.org/uniprotkb/E1BVA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BVA8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 383, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BVA8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BVA8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 281, "end_pos": 283 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BVB5-1", "uniprot_ac": "E1BVB5", "uniprot_id": "E1BVB5_CHICK", "mass": { "chemical_mass": 24789.0, "monoisotopic_mass": 24789.0 }, "refseq": { "ac": "XP_025000869", "name": "LHFPL tetraspan subfamily member 2 protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000869" }, "gene_names": [ { "name": "LHFPL2", "type": "recommended", "evidence": [ { "id": "E1BVB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVB5" } ] }, { "name": "LHFPL2", "type": "synonym", "evidence": [ { "id": "XP_025000869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000869" } ] } ], "protein_names": [ { "name": "LHFPL tetraspan subfamily member 2 protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025000869", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000869" } ] }, { "name": "LHFPL tetraspan subfamily member 2", "type": "synonym", "evidence": [ { "id": "E1BVB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVB5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025000869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000869" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BVB5", "url": "https://www.uniprot.org/uniprotkb/E1BVB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LHFPL2", "url": "https://www.uniprot.org/uniprotkb/E1BVB5", "locus": { "chromosome": "Z", "start_pos": 23258408, "end_pos": 23160515, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012614", "url": "https://www.ensembl.org/id/ENSGALG00010012614" } ] } } ], "crossref": [ { "id": "E1BVB5", "url": "https://alphafold.ebi.ac.uk/entry/E1BVB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004437", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004437", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416369", "url": "https://www.ncbi.nlm.nih.gov/gene/416369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416369", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416369", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKWLVGP", "url": "https://omabrowser.org/oma/group/PKWLVGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025000869", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025000869", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BVB5", "url": "https://www.uniprot.org/uniprotkb/E1BVB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVB5-1", "url": "https://www.uniprot.org/uniprotkb/E1BVB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCHVIVTCRSMLWTLLSIVVAFAELIAFMSADWLIGKAKPASTEDMDNRTGGPQEPYRPTLGIYGRCTRISHMQLSRRDTLCGPYAENFSEIASGFWQATAIFLAVGILILCAVAFVSVFTMCVQSIMKKSIFNVCGLLQGIAGLFLILGLILYPAGWGCQKAISYCGHYASAYKLGDCSLGWAFYTAIGGTILTFICAVFSAQAEIATSSDKVQEEIEEGKNLICLL", "length": 228, "header": "tr|E1BVB5-1|E1BVB5_CHICK Isoform 1 of LHFPL tetraspan subfamily member 2 OS=Gallus gallus OX=9031 GN=LHFPL2 PE=3 SV=1 CANONICAL=E1BVB5-1" }, "isoforms": [ { "isoform_ac": "E1BVB5-1", "url": "https://www.uniprot.org/uniprotkb/E1BVB5/entry#E1BVB5-1", "sequence": { "sequence": "MCHVIVTCRSMLWTLLSIVVAFAELIAFMSADWLIGKAKPASTEDMDNRTGGPQEPYRPTLGIYGRCTRISHMQLSRRDTLCGPYAENFSEIASGFWQATAIFLAVGILILCAVAFVSVFTMCVQSIMKKSIFNVCGLLQGIAGLFLILGLILYPAGWGCQKAISYCGHYASAYKLGDCSLGWAFYTAIGGTILTFICAVFSAQAEIATSSDKVQEEIEEGKNLICLL", "length": 228, "header": "tr|E1BVB5-1|E1BVB5_CHICK Isoform 1 of LHFPL tetraspan subfamily member 2 OS=Gallus gallus OX=9031 GN=LHFPL2 PE=3 SV=1 CANONICAL=E1BVB5-1" }, "locus": { "chromosome": "Z", "start_pos": 23254798, "end_pos": 23242892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030206.1", "url": "https://www.ensembl.org/id/ENSGALT00010030206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017537.1", "url": "https://www.ensembl.org/id/ENSGALP00010017537.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416369", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416369", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A0X7-1", "protein_name": "LHFPL tetraspan subfamily member 2 protein", "gene_name": "Lhfpl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCHVIVTCRSMLWTLLSIVVAFAELVAFMSADWLIGKAKTRSGDEQAGMDSEPHYLGILCLRTPAMQQVPRDTLCGTYAKSFGEIASGFWQATAIFLAMGIFILCVVALVSVFTMCVQSIMRKSIFNVCGLLQGIAGLFLILGLVLYPAGWGCQKAIDCGRYASPYKPGDCSLGWAFYTATGGTVLTFICAVFSAQAEIATSSDKVQEEIEEGKNLICLL", "length": 220 }, "evidence": [ { "id": "E1BVB5", "url": "https://omabrowser.org/oma/group/E1BVB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S2F5-1", "protein_name": "LHFPL tetraspan subfamily member 2 protein", "gene_name": "LHFPL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCHVIVTCRSMLWTLLSIVVAFAELIAFMSADWLIGKAKTRSSAEPGEQGGGSPEPYHPTLGIYARCIRNPGVQHFQRETLCGPYAETFGEIASGFWQATAIFLAMGIFILCMVALVSVFTMCVQSIMKKSIFNVCGLLQGIAGLFLILGLILYPAGWGCQKAIGYCGHYASAYKPGDCSLGWAFYTAIGGTVLTFVCAVFSAQAEIATSSDKVQEEIEEGKNLICLL", "length": 228 }, "evidence": [ { "id": "E1BVB5", "url": "https://omabrowser.org/oma/group/E1BVB5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6P0C6-1", "protein_name": "LHFPL tetraspan subfamily member 2a protein", "gene_name": "lhfpl2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCHVIVTCRSMLWTLLSIVAAFSELIAFLSTDWLVGFPRAPDAGFSPLGATAAGEAYRPTLGIYGRCIRVPHYRRGVLCGPYAVHFGEIASGFWQATAIFLAAGILLLCAVAFISIFTMCFQSIMKKSIFNVCGLLQAIAGLFLIVGLVLYPAGWGSQKVQLYCGPDSSPYRLGLCSAGWAFYTALAGTVLCFLCAVFSAQAEIATSSDKVQEEIQEGKSLICLL", "length": 225 }, "evidence": [ { "id": "E1BVB5", "url": "https://omabrowser.org/oma/group/E1BVB5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZUX7-1", "protein_name": "LHFPL tetraspan subfamily member 2 protein", "gene_name": "LHFPL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCHVIVTCRSMLWTLLSIVVAFAELIAFMSADWLIGKARSRGGVEPAGPGGGSPEPYHPTLGIYARCIRNPGVQHFQRDTLCGPYAESFGEIASGFWQATAIFLAVGIFILCMVALVSVFTMCVQSIMKKSIFNVCGLLQGIAGLFLILGLILYPAGWGCQKAIDYCGHYASAYKPGDCSLGWAFYTAIGGTVLTFICAVFSAQAEIATSSDKVQEEIEEGKNLICLL", "length": 228 }, "evidence": [ { "id": "E1BVB5", "url": "https://omabrowser.org/oma/group/E1BVB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGA2-1", "protein_name": "LHFPL tetraspan subfamily member 2 protein", "gene_name": "Lhfpl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCHVIVTCRSMLWTLLSIVVAFAELVAFMSADWLIGKAKTRSGSGDEQAGMNSEPHYLGILCIRTPAMQQVSRDTLCGTYAKSFGEIASGFWQATAIFLAVGIFILCVVALVSVFTMCVQSIMRKSIFNVCGLLQGIAGLFLILGLILYPAGWGCQKAIDCGRYASPYKPGDCSLGWAFYTATGGTVLTFICAVFSAQAEIATSSDKVQEEIEEGKNLVCLL", "length": 222 }, "evidence": [ { "id": "E1BVB5", "url": "https://omabrowser.org/oma/group/E1BVB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W0X9-1", "protein_name": "Lipoma HMGIC fusion partner-like 2 protein", "gene_name": "CT12588", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCYVIITIASLVWFLCSLVADMLFAVALVTPRWLVGPAQGTDSTASSHHQSSVGIYTRCKVMQEGGFQCGRFDLDGLATDSSVYPNEWKAAMFFVMLGFSLLSVTVILTLITCCRQSACGKSIHNMTACAQVVAGICMMLGLFLHPMGWRANRIQRLCGMDAEPFYPADCSIGVSFYCGIIGVLLTFTAAGISLKAESSNMRTRVRRRVEAGSKLVCIP", "length": 219 }, "evidence": [ { "id": "E1BVB5", "url": "https://omabrowser.org/oma/group/E1BVB5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BVB5", "url": "https://www.uniprot.org/uniprotkb/E1BVB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "E1BVB5", "url": "https://www.uniprot.org/uniprotkb/E1BVB5" } ], "pmid": "" }, { "name": "development of primary female sexual characteristics", "id": "GO:0046545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046545", "evidence": [ { "database": "UniProtKB", "id": "E1BVB5", "url": "https://www.uniprot.org/uniprotkb/E1BVB5" } ], "pmid": "" }, { "name": "development of primary male sexual characteristics", "id": "GO:0046546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046546", "evidence": [ { "database": "UniProtKB", "id": "E1BVB5", "url": "https://www.uniprot.org/uniprotkb/E1BVB5" } ], "pmid": "" }, { "name": "positive regulation of fertilization", "id": "GO:1905516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905516", "evidence": [ { "database": "UniProtKB", "id": "E1BVB5", "url": "https://www.uniprot.org/uniprotkb/E1BVB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BVB5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 228, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BVB5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BVB5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 48, "end_pos": 50 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BVC2-1", "uniprot_ac": "E1BVC2", "uniprot_id": "E1BVC2_CHICK", "mass": { "chemical_mass": 137197.0, "monoisotopic_mass": 137197.0 }, "refseq": { "ac": "XP_414452", "name": "cullin-associated NEDD8-dissociated protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414452" }, "gene_names": [ { "name": "CAND2", "type": "recommended", "evidence": [ { "id": "E1BVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" } ] }, { "name": "CAND2", "type": "synonym", "evidence": [ { "id": "XP_414452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414452" } ] } ], "protein_names": [ { "name": "Cullin associated and neddylation dissociated 2 (putative)", "type": "synonym", "evidence": [ { "id": "E1BVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVC2/entry#names_and_taxonomy" } ] }, { "name": "cullin-associated NEDD8-dissociated protein 1", "type": "synonym", "evidence": [ { "id": "XP_414452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414452" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_414452.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414452" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BVC2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CAND2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2", "locus": { "chromosome": "12", "start_pos": 19657048, "end_pos": 19641317, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019065", "url": "https://www.ensembl.org/id/ENSGALG00010019065" } ] } } ], "crossref": [ { "id": "E1BVC2", "url": "https://alphafold.ebi.ac.uk/entry/E1BVC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008420", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008420", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416121", "url": "https://www.ncbi.nlm.nih.gov/gene/416121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WKLRAKA", "url": "https://omabrowser.org/oma/group/WKLRAKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BVC2", "url": "https://www.orthodb.org/?gene=E1BVC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12696", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12696", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08623", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08623", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BVC2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVC2-1", "url": "https://www.uniprot.org/uniprotkb/E1BVC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASVSYHISSLLEKMTSTDKDFRFMATNDLMMELQKDSIKLDEDSEKKVVKMLLKLLEDKNGEVQNLAVKCLGPLVGKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVISELPPASTGSTMTANVCKKITAQLTGAIGKQEDVSVQLEALDILSDMLSRLGGTLYSFHSSILNCLLPQLTSPRLAVRKRAIIALGHLVLTCSGNTFSELTEHLIAELKKNESTSTTRTYIQCIAGISRQAGHRIGEHLEKIIPLIVQYCNVDDDELREYCFQAFESFVRRCPKEIDPHIPNVMSLCLKYITFDPNYNYDNEEEEEEERMETENGEDEEQESDDEYSDDDDISWKVRRAAAKCLEAIVSSRHDLLQDFYKTLSPVLISRFKEREENVKADIFSAYISLLKQTLPIQSWLHASDDSGKDDVSLTMLQNQVPNIVKALHKQLKDKSIKSRQGCFSLLTELAHVLPGCLAEHIPALVPGIVFSLSDKSNSSNMRIDALSFLHVLLCNHQPEAFHPYIKSLLPPVVACIGDPFYKITSEALLVAQQLVKVIRPLDKPCTFDAKPYVKDLFPGTLKRLKAADIDQEVKERAISCMGQIIYSLGDHLSTDLQPTLKIFLERLKNEITRLTAVKALTLIASSPLKIDLRPILGEGFPILASFLRKNQRALKLSTLAALDILVKNYSDSLKPAMVESVLTELPALISENDMHVSQVAIVFLTTLAKVYPSSISKITSSVLAEIFQLVHSPLLQGGALNAIIDFFQALVLTKAATVGYSELMKQLTAPVYSSGPSGASAALHKQAYYSAAKCVAALSSACPKEAPGTVNQFIQDVKSPKCSSAVKVLAFLSLAEIGRTTNLTSAQKELKTVILDAFASPSEEVKSAASYALGNISVGSLKEYLPFLLKEIESQPKRQYLLLHSLKEVISSSPADSLKPYVEDIWALLFKHCECSEEGTRNVVAECLGKLTLVNPSELLPRLKKQLSSGSPHARSTVVTAVKFTIADHPQPIDTLLKGCIGSFLKTLQDSDLNVRRVALAMFNSAAHNKPSLIRDLLNAVLPSLYNETKVRRELIREVEMGPFKHTVDDGLDVRKAAFECMYTLLESCLDRLDIYEYLNHVEDGLKDHYDIQMLTFIMLARLSTLCPNAVLQRLERLIEPLRATCSTKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVEKSPAMAEFSSQIRSSPEMASLFESIQKDTASLPTTESMDMS", "length": 1237, "header": "tr|E1BVC2-1|E1BVC2_CHICK Isoform 1 of Cullin associated and neddylation dissociated 2 (putative) OS=Gallus gallus OX=9031 GN=CAND2 PE=1 SV=3 CANONICAL=E1BVC2-1" }, "isoforms": [ { "isoform_ac": "E1BVC2-1", "url": "https://www.uniprot.org/uniprotkb/E1BVC2/entry#E1BVC2-1", "sequence": { "sequence": "MASVSYHISSLLEKMTSTDKDFRFMATNDLMMELQKDSIKLDEDSEKKVVKMLLKLLEDKNGEVQNLAVKCLGPLVGKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVISELPPASTGSTMTANVCKKITAQLTGAIGKQEDVSVQLEALDILSDMLSRLGGTLYSFHSSILNCLLPQLTSPRLAVRKRAIIALGHLVLTCSGNTFSELTEHLIAELKKNESTSTTRTYIQCIAGISRQAGHRIGEHLEKIIPLIVQYCNVDDDELREYCFQAFESFVRRCPKEIDPHIPNVMSLCLKYITFDPNYNYDNEEEEEEERMETENGEDEEQESDDEYSDDDDISWKVRRAAAKCLEAIVSSRHDLLQDFYKTLSPVLISRFKEREENVKADIFSAYISLLKQTLPIQSWLHASDDSGKDDVSLTMLQNQVPNIVKALHKQLKDKSIKSRQGCFSLLTELAHVLPGCLAEHIPALVPGIVFSLSDKSNSSNMRIDALSFLHVLLCNHQPEAFHPYIKSLLPPVVACIGDPFYKITSEALLVAQQLVKVIRPLDKPCTFDAKPYVKDLFPGTLKRLKAADIDQEVKERAISCMGQIIYSLGDHLSTDLQPTLKIFLERLKNEITRLTAVKALTLIASSPLKIDLRPILGEGFPILASFLRKNQRALKLSTLAALDILVKNYSDSLKPAMVESVLTELPALISENDMHVSQVAIVFLTTLAKVYPSSISKITSSVLAEIFQLVHSPLLQGGALNAIIDFFQALVLTKAATVGYSELMKQLTAPVYSSGPSGASAALHKQAYYSAAKCVAALSSACPKEAPGTVNQFIQDVKSPKCSSAVKVLAFLSLAEIGRTTNLTSAQKELKTVILDAFASPSEEVKSAASYALGNISVGSLKEYLPFLLKEIESQPKRQYLLLHSLKEVISSSPADSLKPYVEDIWALLFKHCECSEEGTRNVVAECLGKLTLVNPSELLPRLKKQLSSGSPHARSTVVTAVKFTIADHPQPIDTLLKGCIGSFLKTLQDSDLNVRRVALAMFNSAAHNKPSLIRDLLNAVLPSLYNETKVRRELIREVEMGPFKHTVDDGLDVRKAAFECMYTLLESCLDRLDIYEYLNHVEDGLKDHYDIQMLTFIMLARLSTLCPNAVLQRLERLIEPLRATCSTKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVEKSPAMAEFSSQIRSSPEMASLFESIQKDTASLPTTESMDMS", "length": 1237, "header": "tr|E1BVC2-1|E1BVC2_CHICK Isoform 1 of Cullin associated and neddylation dissociated 2 (putative) OS=Gallus gallus OX=9031 GN=CAND2 PE=1 SV=3 CANONICAL=E1BVC2-1" }, "locus": { "chromosome": "12", "start_pos": 19655840, "end_pos": 19641395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046151.1", "url": "https://www.ensembl.org/id/ENSGALT00010046151.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027504.1", "url": "https://www.ensembl.org/id/ENSGALP00010027504.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BVC2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BVC2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BVC2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" } ], "pmid": "" }, { "name": "SCF complex assembly", "id": "GO:0010265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010265", "evidence": [ { "database": "UniProtKB", "id": "E1BVC2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "TBP-class protein binding", "id": "GO:0017025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017025", "evidence": [ { "database": "UniProtKB", "id": "E1BVC2", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 855, "end_pos": 857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BVC2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1237, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BVC2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BVC2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BVC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVC2" }, { "id": "PF08623", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08623" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TATA-binding protein interacting (TIP20)", "eco_id": "ECO_0000259", "start_pos": 1046, "end_pos": 1208, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1060, "end_pos": 1062 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 490, "end_pos": 492 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 855, "end_pos": 857 }, { "start_pos": 888, "end_pos": 890 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BVP9-1", "uniprot_ac": "E1BVP9", "uniprot_id": "E1BVP9_CHICK", "mass": { "chemical_mass": 64892.0, "monoisotopic_mass": 64892.0 }, "refseq": { "ac": "XP_001231650", "name": "pre-mRNA-splicing factor 38B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231650" }, "gene_names": [ { "name": "PRPF38B", "type": "recommended", "evidence": [ { "id": "E1BVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVP9" } ] }, { "name": "PRPF38B", "type": "synonym", "evidence": [ { "id": "XP_001231650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231650" } ] } ], "protein_names": [ { "name": "Pre-mRNA-splicing factor 38B", "type": "recommended", "evidence": [ { "id": "E1BVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVP9/entry#names_and_taxonomy" } ] }, { "name": "pre-mRNA-splicing factor 38B", "type": "synonym", "evidence": [ { "id": "XP_001231650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231650" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231650" } ] }, { "annotation": "May be required for pre-mRNA splicing.", "evidence": [ { "database": "UniProtKB", "id": "E1BVP9", "url": "https://www.uniprot.org/uniprotkb/E1BVP9#function" }, { "database": "UniProtKB", "id": "RU367025", "url": "https://www.uniprot.org/uniprotkb/RU367025#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BVP9", "url": "https://www.uniprot.org/uniprotkb/E1BVP9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRPF38B", "url": "https://www.uniprot.org/uniprotkb/E1BVP9", "locus": {} } ], "crossref": [ { "id": "E1BVP9", "url": "https://alphafold.ebi.ac.uk/entry/E1BVP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001972", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001972", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "768611", "url": "https://www.ncbi.nlm.nih.gov/gene/768611", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768611", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERSHKHD", "url": "https://omabrowser.org/oma/group/ERSHKHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BVP9", "url": "https://www.orthodb.org/?gene=E1BVP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001231650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231650", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BVP9", "url": "https://www.uniprot.org/uniprotkb/E1BVP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVP9-1", "url": "https://www.uniprot.org/uniprotkb/E1BVP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANNSPAVGAGNCQGQQAAQHQPGAVPPAQQQLQSGAPKPAASGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKTIDQQIKSRPRKIKKDGKEGMEEIDRHPERRRSRSPRRSLSPRRSPRRSRSRSHHREAHGSSSFDRELERERERQRLEREAKEREKERRRSRSTDRALERRRSRSRERYRSRSRSRDRKGERRDRDREREKENERSRKKERDYDKDRGSEREKDSDRSRERSKERKSKGDTEERRHRDDKDDKKHRDDKRDSKKERKHSRSRSRERKHRSRSRSKNTGKRSRSRSKEKSSKHKSESKEKSNKRSRSRSRGRTDSVEKSRKRDHSPSKERSRKRSRSKERSHKHDHSDSKDHSDKHDRRRSQSTERESQEKQQKNKDETV", "length": 549, "header": "tr|E1BVP9-1|E1BVP9_CHICK Isoform 1 of Pre-mRNA-splicing factor 38B OS=Gallus gallus OX=9031 GN=PRPF38B PE=1 SV=4 CANONICAL=E1BVP9-1" }, "isoforms": [ { "isoform_ac": "E1BVP9-1", "url": "https://www.uniprot.org/uniprotkb/E1BVP9/entry#E1BVP9-1", "sequence": { "sequence": "MANNSPAVGAGNCQGQQAAQHQPGAVPPAQQQLQSGAPKPAASGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKTIDQQIKSRPRKIKKDGKEGMEEIDRHPERRRSRSPRRSLSPRRSPRRSRSRSHHREAHGSSSFDRELERERERQRLEREAKEREKERRRSRSTDRALERRRSRSRERYRSRSRSRDRKGERRDRDREREKENERSRKKERDYDKDRGSEREKDSDRSRERSKERKSKGDTEERRHRDDKDDKKHRDDKRDSKKERKHSRSRSRERKHRSRSRSKNTGKRSRSRSKEKSSKHKSESKEKSNKRSRSRSRGRTDSVEKSRKRDHSPSKERSRKRSRSKERSHKHDHSDSKDHSDKHDRRRSQSTERESQEKQQKNKDETV", "length": 549, "header": "tr|E1BVP9-1|E1BVP9_CHICK Isoform 1 of Pre-mRNA-splicing factor 38B OS=Gallus gallus OX=9031 GN=PRPF38B PE=1 SV=4 CANONICAL=E1BVP9-1" }, "locus": { "chromosome": "8", "start_pos": 1267781, "end_pos": 1260229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028792.1", "url": "https://www.ensembl.org/id/ENSGALT00010028792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016566.1", "url": "https://www.ensembl.org/id/ENSGALP00010016566.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768611", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768611", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3N166-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "PRPF38B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAAAQQQQQCGSGGTTKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGTEEIDRHAERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRHSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNDREKERSRERSKERRSRGEVEEKKHKEDKDDRRHRDDKKDSKKERKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNDSKEKSNKRSRSGSQGRTDSVEKRKREHSPSKEKSRKRSGSKERSHKRDHSDSKDQSDKRDRRRSQSIETESQEKQHKDKEETV", "length": 543 }, "evidence": [ { "id": "E1BVP9", "url": "https://omabrowser.org/oma/group/E1BVP9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54J00-1", "protein_name": "Pre-mRNA-splicing factor 38", "gene_name": "prpf38b", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSLETFGNEKSMNLDNVLLTNIQSSLYFKNLYPKRSYHEVIEEIKRNVEILAPYIPNTKTPSTTFCLLYKFFLMKLTVKQMKGLLGNNESPYIRAIGALYLRYCHPPANLWDWYVDYLDDQETVFISKNTEVTIQRFLLDLLKDNKFSGTVLPRIPTKIQQDLDKKIKDYEIENNLTYNNNNNNTKKDSYSRDNRDNRDNRDSRDSRDSRDSRDNYRYSRDSRDSRDSRDNHRDSYRDRDSYSRDRDRDNRDSYRDNYRDSYRNNSRYNNDDNGKDSYAEELERFKNERNKSSGSGGRNYSKRDDYDDYSKSRSNDRDRDRDYSSSSGGNGNGYKRDSYYSDDDDDSEDGRTYGGRKRSRSRSNSRDRDSKNNSTQKETTTTTTTATTTTEKQPKEESESLKKLRSLYGATSDQVSLD", "length": 418 }, "evidence": [ { "id": "E1BVP9", "url": "https://omabrowser.org/oma/group/E1BVP9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5VTL8-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "PRPF38B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAAAQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV", "length": 546 }, "evidence": [ { "id": "E1BVP9", "url": "https://omabrowser.org/oma/group/E1BVP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AXY7-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "Prpf38b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAVVQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGVEEIDRHIERRRSRSPRRSLSPRRSPRRSRSRSHHRDGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSLDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKDRGNDRERDRERSRERSKEQRSRGEGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKDKASKHKNESKEKSNKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKRDHDSKDQSDRQDHQRSQSVEPESQEKEHKNKDETV", "length": 542 }, "evidence": [ { "id": "E1BVP9", "url": "https://omabrowser.org/oma/group/E1BVP9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80SY5-1", "protein_name": "Pre-mRNA-splicing factor 38B", "gene_name": "Prpf38b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANNSPALTGNSQPQHQAAAAVTQQQQQCGGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGIEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGSDRERDRERSRERSKEQRSRGDGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRNAGKRSRSRSKDKSSRHKNESKEKANKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKREHNDSKDQSDRQDHQSSQSGEPESQEKEHKSKDETV", "length": 542 }, "evidence": [ { "id": "E1BVP9", "url": "https://omabrowser.org/oma/group/E1BVP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "E1BVP9", "url": "https://www.uniprot.org/uniprotkb/E1BVP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "E1BVP9", "url": "https://www.uniprot.org/uniprotkb/E1BVP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BVP9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 549, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BVP9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BVP9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BW34-1", "uniprot_ac": "E1BW34", "uniprot_id": "E1BW34_CHICK", "mass": { "chemical_mass": 32432.0, "monoisotopic_mass": 32432.0 }, "refseq": { "ac": "XP_001232593", "name": "protein Largen", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232593" }, "gene_names": [ { "name": "PRR16", "type": "recommended", "evidence": [ { "id": "E1BW34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW34" } ] }, { "name": "PRR16", "type": "synonym", "evidence": [ { "id": "XP_001232593", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232593" } ] } ], "protein_names": [ { "name": "Proline rich 16", "type": "synonym", "evidence": [ { "id": "E1BW34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW34/entry#names_and_taxonomy" } ] }, { "name": "protein Largen", "type": "synonym", "evidence": [ { "id": "XP_001232593", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232593" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_001232593.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232593", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232593" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BW34", "url": "https://www.uniprot.org/uniprotkb/E1BW34" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRR16", "url": "https://www.uniprot.org/uniprotkb/E1BW34", "locus": { "chromosome": "Z", "start_pos": 71691081, "end_pos": 71840414, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009726", "url": "https://www.ensembl.org/id/ENSGALG00010009726" } ] } } ], "crossref": [ { "id": "E1BW34", "url": "https://alphafold.ebi.ac.uk/entry/E1BW34", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002183", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002183", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769337", "url": "https://www.ncbi.nlm.nih.gov/gene/769337", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769337", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769337", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGKLPHQ", "url": "https://omabrowser.org/oma/group/PGKLPHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BW34", "url": "https://www.orthodb.org/?gene=E1BW34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15917:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15917:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15252", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15252", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001232593", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232593", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BW34", "url": "https://www.uniprot.org/uniprotkb/E1BW34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BW34-1", "url": "https://www.uniprot.org/uniprotkb/E1BW34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAQSKGTASSSSSPSEGPPAASKAKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSSTTASSLEKVKVRGSTPLIKNPVHPSAILTVLRKPNPPPPPPRLTPVKCDKQLRPPPSANPVKTNGTLLRNGPSRIPNGDLCCIPNSNLDSVAIPPLMHRPEKERCPQAGARERVRFSEKVQYHGYCPDCDVRYNIKNREVHLHSEPAHLLGALPHQCPPLPPPPPPLPPFPLENGGLGISSSNSFPPPRPVTVPPQTAPKPQKTILRKSTTTTV", "length": 301, "header": "tr|E1BW34-1|E1BW34_CHICK Isoform 1 of Proline rich 16 OS=Gallus gallus OX=9031 GN=PRR16 PE=4 SV=2 CANONICAL=E1BW34-1" }, "isoforms": [ { "isoform_ac": "E1BW34-1", "url": "https://www.uniprot.org/uniprotkb/E1BW34/entry#E1BW34-1", "sequence": { "sequence": "MSAQSKGTASSSSSPSEGPPAASKAKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSSTTASSLEKVKVRGSTPLIKNPVHPSAILTVLRKPNPPPPPPRLTPVKCDKQLRPPPSANPVKTNGTLLRNGPSRIPNGDLCCIPNSNLDSVAIPPLMHRPEKERCPQAGARERVRFSEKVQYHGYCPDCDVRYNIKNREVHLHSEPAHLLGALPHQCPPLPPPPPPLPPFPLENGGLGISSSNSFPPPRPVTVPPQTAPKPQKTILRKSTTTTV", "length": 301, "header": "tr|E1BW34-1|E1BW34_CHICK Isoform 1 of Proline rich 16 OS=Gallus gallus OX=9031 GN=PRR16 PE=4 SV=2 CANONICAL=E1BW34-1" }, "locus": { "chromosome": "Z", "start_pos": 71840327, "end_pos": 71735774, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023222.1", "url": "https://www.ensembl.org/id/ENSGALT00010023222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013437.1", "url": "https://www.ensembl.org/id/ENSGALP00010013437.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769337", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B223-1", "protein_name": "Proline rich 16", "gene_name": "PRR16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"E1BW34", "url": "https://omabrowser.org/oma/group/E1BW34/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SPA5-1", "protein_name": "Proline rich 16", "gene_name": "PRR16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAKSKGTPSSSSPAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKVQANAPLIKPPAHPSAILTVLRKPNPPAPPPRLTPVKCEDSQRVVPTVNPVKTNGTLLRNGGFPGAPTKIPNGDIYCKPSSNLDKAPGQPLMHRPEKDRCPQAGPRERVRFNEKVQYHGYCPDCDTRYHVKNREVHLHSEPVHPPGKLPPQGPPHPLPPHLPPFPLENGGLGISHSNSFPPLRPATVPPPIAPKPQKTILRKSTTTTV", "length": 304 }, "evidence": [ { "id": "E1BW34", "url": "https://omabrowser.org/oma/group/E1BW34/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A3KMN5-1", "protein_name": "Protein Largen", "gene_name": "Prr16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAKSKGNPSSSSAAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSIEKIKEQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVRCEEPQRVVPTANPVKTNGTLLRNGGLAGRPNKIPNGDICCIPNSNLDKAPLQSLMHRPEKDRSPQAGPRERVRFNEKVQYHGYCPDCESRYNIKNREVHLHSEPVHPPGKIPHQGPLLHPPPHLPNFPLENGGLGISHSNSFPPPTPATVPPPAAPKPQKTILRKSTTTTV", "length": 304 }, "evidence": [ { "id": "E1BW34", "url": "https://omabrowser.org/oma/group/E1BW34/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q569H4-1", "protein_name": "Protein Largen", "gene_name": "PRR16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAKSKGNPSSSCPAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEVVDQIDTLTSDLQLEDEMTDSSKTDTLNSSSSGTTASSLEKIKVQANAPLIKPPAHPSAILTVLRKPNPPPPPPRLTPVKCEDPKRVVPTANPVKTNGTLLRNGGLPGGPNKIPNGDICCIPNSNLDKAPVQLLMHRPEKDRCPQAGPRERVRFNEKVQYHGYCPDCDTRYNIKNREVHLHSEPVHPPGKIPHQGPPLPPTPHLPPFPLENGGMGISHSNSFPPIRPATVPPPTAPKPQKTILRKSTTTTV", "length": 304 }, "evidence": [ { "id": "E1BW34", "url": "https://omabrowser.org/oma/group/E1BW34/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "E1BW34", "url": "https://www.uniprot.org/uniprotkb/E1BW34" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "E1BW34", "url": "https://www.uniprot.org/uniprotkb/E1BW34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BW34-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 301, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BW34-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BW34" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_003641822.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641822" } ] }, { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. 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"https://www.uniprot.org/uniprotkb/E1BW98" } ], "pmid": "" }, { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "E1BW98", "url": "https://www.uniprot.org/uniprotkb/E1BW98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1BW98", "url": "https://www.uniprot.org/uniprotkb/E1BW98" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "E1BW98", "url": "https://www.uniprot.org/uniprotkb/E1BW98" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "E1BW98", "url": "https://www.uniprot.org/uniprotkb/E1BW98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BW98-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 340, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BW98-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BW98" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BWA9-1", "uniprot_ac": "E1BWA9", "uniprot_id": "E1BWA9_CHICK", "mass": { "chemical_mass": 24811.0, "monoisotopic_mass": 24811.0 }, "refseq": { "ac": "NP_001091115", "name": "protein FAM3C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091115" }, "gene_names": [ { "name": "FAM3C", "type": "recommended", "evidence": [ { "id": "E1BWA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ] }, { "name": "FAM3C", "type": "synonym", "evidence": [ { "id": "NP_001091115", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091115" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 3, member C", "type": "synonym", "evidence": [ { "id": "E1BWA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA9/entry#names_and_taxonomy" } ] }, { "name": "protein FAM3C", "type": "synonym", "evidence": [ { "id": "NP_001091115", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091115" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267653.23249.1, SRR13267649.18648.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On May 23, 2007 this sequence version replaced XP_416002.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001091115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091115" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM3C", "url": "https://www.uniprot.org/uniprotkb/E1BWA9", "locus": { "chromosome": "1", "start_pos": 23402604, "end_pos": 23373060, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001264", "url": "https://www.ensembl.org/id/ENSGALG00010001264" } ] } } ], "crossref": [ { "id": "E1BWA9", "url": "https://alphafold.ebi.ac.uk/entry/E1BWA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008975", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13940", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13940", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417758", "url": "https://www.ncbi.nlm.nih.gov/gene/417758", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039220", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039220", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417758", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417758", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0X4U5", "url": "https://www.orthodb.org/?gene=A0A8V0X4U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7P7", "url": "https://www.orthodb.org/?gene=A0A8V0X7P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XAC3", "url": "https://www.orthodb.org/?gene=A0A8V0XAC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BWA9", "url": "https://www.orthodb.org/?gene=E1BWA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001091115", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091115", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X4U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X4U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XAC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XAC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BWA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIAGAAKLIVVIAIFLLTFYVISQVFEIKMEANLGHIFARSALDAAARSTKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICVEDNVLMSGVKNNVGRGINVALVNGKTGEPLDTKFFDMWGGDVAPFIEFLKSIQDGTIVLMGTYDDGATKLNEEARKLIAELGSTSITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD", "length": 227, "header": "tr|E1BWA9-1|E1BWA9_CHICK Isoform 1 of Family with sequence similarity 3, member C OS=Gallus gallus OX=9031 GN=FAM3C PE=1 SV=1 CANONICAL=E1BWA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X4U5-1", "url": "https://www.uniprot.org/uniprotkb/E1BWA9/entry#A0A8V0X4U5-1", "sequence": { "sequence": "MRIAVYIYSHMQWETKSKLQANKKVFYFLLKATKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICVEDNVLMSGVKNNVGRGINVALVNGKTGEPLDTKFFDMWGGDVAPFIEFLKSIQDGTIVLMGTYDDGATKLNEEARKLIAELGSTSITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD", "length": 209, "header": "tr|A0A8V0X4U5-1|A0A8V0X4U5_CHICK Computationally mapped isoform of Family with sequence similarity 3, member C OS=Gallus gallus OX=9031 GN=FAM3C PE=1 SV=1 CANONICAL=E1BWA9-1" }, "locus": { "chromosome": "1", "start_pos": 23400770, "end_pos": 23386611, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002919.1", "url": "https://www.ensembl.org/id/ENSGALT00010002919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001465.1", "url": "https://www.ensembl.org/id/ENSGALP00010001465.1" } ] } }, { "isoform_ac": "A0A8V0X7P7-1", "url": "https://www.uniprot.org/uniprotkb/E1BWA9/entry#A0A8V0X7P7-1", "sequence": { "sequence": "MRIAGAAKLIVVIAIFLLTFYVISQVFEIKMEANLGHIFARSALDAAARSTKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICVEDNVLMSGVKNNVGRGINVALVNDVAPFIEFLKSIQDGTIVLMGTYDDGATKLNEEARKLIAELGSTSITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD", "length": 210, "header": "tr|A0A8V0X7P7-1|A0A8V0X7P7_CHICK Computationally mapped isoform of Family with sequence similarity 3, member C OS=Gallus gallus OX=9031 GN=FAM3C PE=1 SV=1 CANONICAL=E1BWA9-1" }, "locus": { "chromosome": "1", "start_pos": 23400770, "end_pos": 23386611, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002917.1", "url": "https://www.ensembl.org/id/ENSGALT00010002917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001463.1", "url": "https://www.ensembl.org/id/ENSGALP00010001463.1" } ] } }, { "isoform_ac": "A0A8V0XAC3-1", "url": "https://www.uniprot.org/uniprotkb/E1BWA9/entry#A0A8V0XAC3-1", "sequence": { "sequence": "GAAKLIVVIAIFLLTFYVISQVFEIKMEANLGHIFARSALDAAARSTKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICVEDNVLMSGVKNNVGRGINVALVNGKTGEPLDTKFFDMWGGDVAPFIEFLKSIQDGTIVLMGTYDDGATKLNEEARKLIAELGSTSITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD", "length": 223, "header": "tr|A0A8V0XAC3-1|A0A8V0XAC3_CHICK Computationally mapped isoform of Family with sequence similarity 3, member C OS=Gallus gallus OX=9031 GN=FAM3C PE=1 SV=1 CANONICAL=E1BWA9-1" }, "locus": { "chromosome": "1", "start_pos": 23400770, "end_pos": 23389119, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002918.1", "url": "https://www.ensembl.org/id/ENSGALT00010002918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001464.1", "url": "https://www.ensembl.org/id/ENSGALP00010001464.1" } ] } }, { "isoform_ac": "E1BWA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BWA9/entry#E1BWA9-1", "sequence": { "sequence": "MRIAGAAKLIVVIAIFLLTFYVISQVFEIKMEANLGHIFARSALDAAARSTKPPRYKCGISKACPEKHFAFKMASGAANVVGPKICVEDNVLMSGVKNNVGRGINVALVNGKTGEPLDTKFFDMWGGDVAPFIEFLKSIQDGTIVLMGTYDDGATKLNEEARKLIAELGSTSITNLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKQD", "length": 227, "header": "tr|E1BWA9-1|E1BWA9_CHICK Isoform 1 of Family with sequence similarity 3, member C OS=Gallus gallus OX=9031 GN=FAM3C PE=1 SV=1 CANONICAL=E1BWA9-1" }, "locus": { "chromosome": "1", "start_pos": 23400770, "end_pos": 23386611, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002920.1", "url": "https://www.ensembl.org/id/ENSGALT00010002920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001466.1", "url": "https://www.ensembl.org/id/ENSGALP00010001466.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417758", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417758", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BWA9", "url": "https://www.uniprot.org/uniprotkb/E1BWA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BWY1-1", "uniprot_ac": "E1BWY1", "uniprot_id": "E1BWY1_CHICK", "mass": { "chemical_mass": 31453.0, "monoisotopic_mass": 31453.0 }, "refseq": { "ac": "XP_015131580", "name": "protein LRATD1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131580" }, "gene_names": [ { "name": "FAM84A", "type": "recommended", "evidence": [ { "id": "E1BWY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWY1" } ] }, { "name": "FAM84A", "type": "synonym", "evidence": [ { "id": "XP_015131580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131580" } ] } ], "protein_names": [ { "name": "LRAT domain containing 1", "type": "synonym", "evidence": [ { "id": "E1BWY1", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131580" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BWY1", "url": "https://www.uniprot.org/uniprotkb/E1BWY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM84A", "url": "https://www.uniprot.org/uniprotkb/E1BWY1", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000016459", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016459", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421946", "url": "https://www.ncbi.nlm.nih.gov/gene/421946", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007053", "url": 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[ "Protein Classification" ] }, { "id": "PF04970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015131580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131580", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BWY1", "url": "https://www.uniprot.org/uniprotkb/E1BWY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWY1-1", "url": "https://www.uniprot.org/uniprotkb/E1BWY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDEEEDLDERGQPDKYSVKGSGSPDQETPTHHLHHQLVLNETQFSAFRGQECIFSKVSSGPQAGDLSVYSVSALPALCKPGDLLELLYLGPSEQPPPHWAVYVGSGQIIHLHQGQIRQDSLYEAPAGNVGRVVNSWYRFRPLVAELVVQNACGHLGLKSDEICWTNSESFAAWCRFGKREFKAGGELQAAAGTQQQYYLKIHLAENKVHTVRFHSLEDLIREKRRIDASGKLRVIKDLAIVDGKE", "length": 282, "header": "tr|E1BWY1-1|E1BWY1_CHICK Isoform 1 of LRAT domain containing 1 OS=Gallus gallus 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"MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDEEEDLDERGQPDKFGVKAPPGCAPCPESPSRHHHHHHHHHLLHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHLCQGEIRQDSLYEAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLADNKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE", "length": 297 }, "evidence": [ { "id": "E1BWY1", "url": "https://omabrowser.org/oma/group/E1BWY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96KN4-1", "protein_name": "Protein LRATD1", "gene_name": "LRATD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDDEEDLDERGQPDKFGVKAPPGCTPCPESPSRHHHHLLHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHLHQGEIRQDSLYEAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLGENKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE", "length": 292 }, "evidence": [ { "id": "E1BWY1", "url": 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mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"NP_001186349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186349" } ] } ], "protein_names": [ { "name": "Metallophosphoesterase MPPED2", "type": "recommended", "evidence": [ { "id": "E1BXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXB8/entry#names_and_taxonomy" } ] }, { "name": "Metallophosphoesterase domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "E1BXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXB8/entry#names_and_taxonomy" } ] }, { "name": "metallophosphoesterase MPPED2", "type": "synonym", "evidence": [ { "id": "NP_001186349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186349" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267647.8509.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000212.1. On Dec 8, 2010 this sequence version replaced XP_419641.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186349" } ] }, { "annotation": "Displays low metallophosphoesterase activity (in vitro). May play a role in the development of the nervous system.", "evidence": [ { "database": "UniProtKB", "id": "E1BXB8", "url": "https://www.uniprot.org/uniprotkb/E1BXB8#function" }, { "database": "UniProtKB", "id": "ARBA00057840", "url": "https://www.uniprot.org/uniprotkb/ARBA00057840#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXB8", "url": "https://www.uniprot.org/uniprotkb/E1BXB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPPED2", "url": "https://www.uniprot.org/uniprotkb/E1BXB8", "locus": { "chromosome": "5", "start_pos": 4799803, "end_pos": 4900066, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022622", "url": "https://www.ensembl.org/id/ENSGALG00010022622" } ] } } ], "crossref": [ { "id": "E1BXB8", "url": "https://alphafold.ebi.ac.uk/entry/E1BXB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012136", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012136", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07379", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07379", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421604", "url": "https://www.ncbi.nlm.nih.gov/gene/421604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051693", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051693", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421604", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421604", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTPPYGI", "url": "https://omabrowser.org/oma/group/HTPPYGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP73", "url": "https://www.orthodb.org/?gene=A0A8V0ZP73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXB8", "url": "https://www.orthodb.org/?gene=E1BXB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12905:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12905:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186349", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXB8", "url": "https://www.uniprot.org/uniprotkb/E1BXB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXB8-1", "url": "https://www.uniprot.org/uniprotkb/E1BXB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPTPQGS", "length": 294, "header": "tr|E1BXB8-1|E1BXB8_CHICK Isoform 1 of Metallophosphoesterase MPPED2 OS=Gallus gallus OX=9031 GN=MPPED2 PE=3 SV=1 CANONICAL=E1BXB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIV1-1", "url": "https://www.uniprot.org/uniprotkb/E1BXB8/entry#A0A8V0ZIV1-1", "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGMHSQG", "length": 109, "header": "tr|A0A8V0ZIV1-1|A0A8V0ZIV1_CHICK Computationally mapped isoform of Metallophosphoesterase domain containing 2 OS=Gallus gallus OX=9031 GN=MPPED2 PE=4 SV=1 CANONICAL=E1BXB8-1" }, "locus": { "chromosome": "5", "start_pos": 4891574, "end_pos": 4863868, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055038.1", "url": "https://www.ensembl.org/id/ENSGALT00010055038.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033276.1", "url": "https://www.ensembl.org/id/ENSGALP00010033276.1" } ] } }, { "isoform_ac": "A0A8V0ZP73-1", "url": "https://www.uniprot.org/uniprotkb/E1BXB8/entry#A0A8V0ZP73-1", "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLDLVFHCQHGRNPNA", "length": 117, "header": "tr|A0A8V0ZP73-1|A0A8V0ZP73_CHICK Computationally mapped isoform of Metallophosphoesterase domain containing 2 OS=Gallus gallus OX=9031 GN=MPPED2 PE=4 SV=1 CANONICAL=E1BXB8-1" }, "locus": { "chromosome": "5", "start_pos": 4891574, "end_pos": 4849841, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055041.1", "url": "https://www.ensembl.org/id/ENSGALT00010055041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033278.1", "url": "https://www.ensembl.org/id/ENSGALP00010033278.1" } ] } }, { "isoform_ac": "E1BXB8-1", "url": "https://www.uniprot.org/uniprotkb/E1BXB8/entry#E1BXB8-1", "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPTPQGS", "length": 294, "header": "tr|E1BXB8-1|E1BXB8_CHICK Isoform 1 of Metallophosphoesterase MPPED2 OS=Gallus gallus OX=9031 GN=MPPED2 PE=3 SV=1 CANONICAL=E1BXB8-1" }, "locus": { "chromosome": "5", "start_pos": 4891574, "end_pos": 4801149, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055045.1", "url": "https://www.ensembl.org/id/ENSGALT00010055045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033281.1", "url": "https://www.ensembl.org/id/ENSGALP00010033281.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421604", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QPQ5-1", "protein_name": "Metallophosphoesterase MPPED2", "gene_name": "Mpped2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEITVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQGS", "length": 294 }, "evidence": [ { "id": "E1BXB8", "url": "https://omabrowser.org/oma/group/E1BXB8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B1WBP0-1", "protein_name": "Metallophosphoesterase MPPED2", "gene_name": "Mpped2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGTDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGTMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQGS", "length": 294 }, "evidence": [ { "id": "E1BXB8", "url": "https://omabrowser.org/oma/group/E1BXB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SGP0-1", "protein_name": "Metallophosphoesterase MPPED2", "gene_name": "MPPED2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRVRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQGS", "length": 294 }, "evidence": [ { "id": "E1BXB8", "url": "https://omabrowser.org/oma/group/E1BXB8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9CZJ0-1", "protein_name": "Metallophosphoesterase MPPED2", "gene_name": "Mpped2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHGIPSQGKVTITVDEYSSNPTQAFTHYNINQSRFQPPHVHMVDPIPYDTPKPAGHTRFVCISDTHSRTDGIQMPYGDILLHTGDFTELGLPSEVKKFNDWLGNLPYEYKIVIAGNHELTFDKEFMADLVKQDYYRFPSVSKLKPEDFDNVQSLLTNSIYLQDSEVTVKGFRIYGAPWTPWFNGWGFNLPRGQSLLDKWNLIPEGIDILMTHGPPLGFRDWVPKELQRVGCVELLNTVQRRIRPKLHVFGGIHEGYGIMTDGYTTYINASTCTVSFQPTNPPIIFDLPNPQGS", "length": 294 }, "evidence": [ { "id": "E1BXB8", "url": "https://omabrowser.org/oma/group/E1BXB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BXB8", "url": "https://www.uniprot.org/uniprotkb/E1BXB8" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "E1BXB8", "url": "https://www.uniprot.org/uniprotkb/E1BXB8" } ], "pmid": "" }, { "name": "cyclic-nucleotide phosphodiesterase activity", "id": "GO:0004112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004112", "evidence": [ { "database": "UniProtKB", "id": "E1BXB8", "url": "https://www.uniprot.org/uniprotkb/E1BXB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BXB8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 294, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BXB8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BXB8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXB8" }, { "id": "PF00149", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcineurin-like phosphoesterase", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 255, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXC9-1", "uniprot_ac": "E1BXC9", "uniprot_id": "E1BXC9_CHICK", "mass": { "chemical_mass": 29587.0, "monoisotopic_mass": 29587.0 }, "refseq": { "ac": "NP_001186255", "name": "BTB/POZ domain-containing protein KCTD4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186255" }, "gene_names": [ { "name": "KCTD4", "type": "recommended", "evidence": [ { "id": "E1BXC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXC9" } ] }, { "name": "KCTD4", "type": "synonym", "evidence": [ { "id": "NP_001186255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186255" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD4", "type": "synonym", "evidence": [ { "id": "NP_001186255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186255" } ] }, { "name": "Potassium channel tetramerization domain containing 4", "type": "synonym", "evidence": [ { "id": "E1BXC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXC9/entry#names_and_taxonomy" } ] }, { "name": "potassium channel tetramerisation domain containing 4", "type": "synonym", "evidence": [ { "id": "NP_001186255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186255" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: BX933963.2, BX935574.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000027.1. On Dec 4, 2010 this sequence version replaced XP_001232057.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186255" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXC9", "url": "https://www.uniprot.org/uniprotkb/E1BXC9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD4", "url": "https://www.uniprot.org/uniprotkb/E1BXC9", "locus": { "chromosome": "1", "start_pos": 167576863, "end_pos": 167582973, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003519", "url": "https://www.ensembl.org/id/ENSGALG00010003519" } ] } } ], "crossref": [ { "id": "E1BXC9", "url": "https://alphafold.ebi.ac.uk/entry/E1BXC9", "database": 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"Protein Classification", "Other" ] }, { "id": "PF19323", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19323", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186255", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BXC9", "url": "https://www.uniprot.org/uniprotkb/E1BXC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXC9-1", "url": "https://www.uniprot.org/uniprotkb/E1BXC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERKSNRRAKESEENHSNFEGSEQDKDYKTSLITLNVGGYLYITQKQTLTKYPDSFLEGVINGKIMCPFDADGHYFIDRDGLLFRHILNFLRNGELLLPEGFRENQLLAHEADFFQLKVLSDAVKSRWEKEQLASRETTFLEITDSHDRSQGLRIFCNAPDFIAKIKSRIVLVSKSRLDGFPEEFSVSSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 257, "header": "tr|E1BXC9-1|E1BXC9_CHICK Isoform 1 of Potassium channel tetramerization domain containing 4 OS=Gallus gallus OX=9031 GN=KCTD4 PE=4 SV=1 CANONICAL=E1BXC9-1" }, "isoforms": [ { "isoform_ac": "E1BXC9-1", "url": "https://www.uniprot.org/uniprotkb/E1BXC9/entry#E1BXC9-1", "sequence": { "sequence": "MERKSNRRAKESEENHSNFEGSEQDKDYKTSLITLNVGGYLYITQKQTLTKYPDSFLEGVINGKIMCPFDADGHYFIDRDGLLFRHILNFLRNGELLLPEGFRENQLLAHEADFFQLKVLSDAVKSRWEKEQLASRETTFLEITDSHDRSQGLRIFCNAPDFIAKIKSRIVLVSKSRLDGFPEEFSVSSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 257, "header": "tr|E1BXC9-1|E1BXC9_CHICK Isoform 1 of Potassium channel tetramerization domain containing 4 OS=Gallus gallus OX=9031 GN=KCTD4 PE=4 SV=1 CANONICAL=E1BXC9-1" }, "locus": { "chromosome": "1", "start_pos": 167578615, "end_pos": 167577845, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008211.1", "url": "https://www.ensembl.org/id/ENSGALT00010008211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004884.1", "url": "https://www.ensembl.org/id/ENSGALP00010004884.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769400", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6H6X4-1", "protein_name": "BTB/POZ domain-containing protein KCTD4", "gene_name": "KCTD4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEHKINRREKEKDYEGKHNSLEDADQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSISSNTIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 259 }, "evidence": [ { "id": "E1BXC9", "url": "https://omabrowser.org/oma/group/E1BXC9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZXL9-1", "protein_name": "Potassium channel tetramerization domain containing 4", "gene_name": "Kctd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERKIIRREKEREYEGRHNSLEDAEQGKNCTSTLTTLNVGGYLYITQRQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWKKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSVSSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 259 }, "evidence": [ { "id": "E1BXC9", "url": "https://omabrowser.org/oma/group/E1BXC9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H835-1", "protein_name": "BTB/POZ domain-containing protein KCTD4", "gene_name": "Kctd4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERKIIRREKEREYEGRHNSLEDAEQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGVVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSVSSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 259 }, "evidence": [ { "id": "E1BXC9", "url": "https://omabrowser.org/oma/group/E1BXC9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LNK6-1", "protein_name": "Potassium channel tetramerization domain containing 4", "gene_name": "KCTD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERKINRREKEKEYEGKHNSLEDADQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 259 }, "evidence": [ { "id": "E1BXC9", "url": "https://omabrowser.org/oma/group/E1BXC9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8WVF5-1", "protein_name": "BTB/POZ domain-containing protein KCTD4", "gene_name": "KCTD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERKINRREKEKEYEGKHNSLEDTDQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSISSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 259 }, "evidence": [ { "id": "E1BXC9", "url": "https://omabrowser.org/oma/group/E1BXC9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7X1-1", "protein_name": "BTB/POZ domain-containing protein KCTD4", "gene_name": "Kctd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERKIIRREKEREYEGRHNSVEDAEQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSVSSNIIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK", "length": 259 }, "evidence": [ { "id": "E1BXC9", "url": "https://omabrowser.org/oma/group/E1BXC9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "E1BXC9", "url": "https://www.uniprot.org/uniprotkb/E1BXC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BXC9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 257, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BXC9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BXC9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 202, "end_pos": 204 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXD5-1", "uniprot_ac": "E1BXD5", "uniprot_id": "E1BXD5_CHICK", "mass": { "chemical_mass": 70872.0, "monoisotopic_mass": 70872.0 }, "refseq": { "ac": "XP_025002557", "name": "ecto-NOX disulfide-thiol exchanger 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002557" }, "gene_names": [ { "name": "ENOX1", "type": "recommended", "evidence": [ { "id": "E1BXD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ] }, { "name": "ENOX1", "type": "synonym", "evidence": [ { "id": "XP_025002557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002557" } ] } ], "protein_names": [ { "name": "Ecto-NOX disulfide-thiol exchanger 1", "type": "synonym", "evidence": [ { "id": "E1BXD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXD5/entry#names_and_taxonomy" } ] }, { "name": "ecto-NOX disulfide-thiol exchanger 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025002557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002557" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025002557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002557" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENOX1", "url": "https://www.uniprot.org/uniprotkb/E1BXD5", "locus": { "chromosome": "1", "start_pos": 166671040, "end_pos": 167037555, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003372", "url": "https://www.ensembl.org/id/ENSGALG00010003372" } ] } } ], "crossref": [ { "id": "E1BXD5", "url": "https://alphafold.ebi.ac.uk/entry/E1BXD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016967", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016967", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418839", "url": "https://www.ncbi.nlm.nih.gov/gene/418839", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16001:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23267", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23267", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025002557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025002557", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PCJ5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PCJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PCJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXD5-1", "url": "https://www.uniprot.org/uniprotkb/E1BXD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAADGLGSIAIDTTQLNMSVTDPTAWATAMNNLGMVPVGLAGQQLVTDSICVPGFDPSLSMMTGITPINPMIPGMGLVPPPPPTDVPVVKEIIHCKSCTLFPPNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMLAREERHRRKMEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLTWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKAAHEQEMEQAKESFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAHSEQLMGIRREEEMEMSDDDSGDNPSKKLRVDDSALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKGQLFRTEESLTKDQQLQFLQQTMQGMQQQLLSIQEELNNKKSELEQAKEEQTHTQAMLKVLQEQLKSAKELAEINGHDESQANEINVLTVALVNQDREKTSEKRSPGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSRISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKFCAFEGIKTV", "length": 623, "header": "tr|E1BXD5-1|E1BXD5_CHICK Isoform 1 of Ecto-NOX disulfide-thiol exchanger 1 OS=Gallus gallus OX=9031 GN=ENOX1 PE=3 SV=2 CANONICAL=E1BXD5-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PCJ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BXD5/entry#A0A1D5PCJ5-1", "sequence": { "sequence": "MAAAADGLGSIAIDTTQLNMSVTDPTAWATAMNNLGMVPVGLAGQQLVTDSICVPGFDPSLSMMTGITPINPMIPGMGLVPPPPPTDVPVVKEIIHCKSCTLFPPNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMLAREERHRRKMEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLTWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKAAHEQEMEQAKESFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAHSEQLMGIRREEEMEMSDDDSGDNPSKKLRVDDSALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKGQLFRTEESLTKDQQLQFLQQTMQGMQQQLLSIQEELNNKKSELEQAKEEQTHTQAMLKVLQEQEINVLTVALVNQDREKTSEKRSPGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSRISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKFCAFEGIKTV", "length": 604, "header": "tr|A0A1D5PCJ5-1|A0A1D5PCJ5_CHICK Computationally mapped isoform of Ecto-NOX disulfide-thiol exchanger 1 OS=Gallus gallus OX=9031 GN=ENOX1 PE=3 SV=1 CANONICAL=E1BXD5-1" }, "locus": { "chromosome": "1", "start_pos": 166813118, "end_pos": 166671878, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007875.1", "url": "https://www.ensembl.org/id/ENSGALT00010007875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004728.1", "url": "https://www.ensembl.org/id/ENSGALP00010004728.1" } ] } }, { "isoform_ac": "E1BXD5-1", "url": "https://www.uniprot.org/uniprotkb/E1BXD5/entry#E1BXD5-1", "sequence": { "sequence": "MAAAADGLGSIAIDTTQLNMSVTDPTAWATAMNNLGMVPVGLAGQQLVTDSICVPGFDPSLSMMTGITPINPMIPGMGLVPPPPPTDVPVVKEIIHCKSCTLFPPNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMLAREERHRRKMEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLTWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKAAHEQEMEQAKESFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAHSEQLMGIRREEEMEMSDDDSGDNPSKKLRVDDSALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKGQLFRTEESLTKDQQLQFLQQTMQGMQQQLLSIQEELNNKKSELEQAKEEQTHTQAMLKVLQEQLKSAKELAEINGHDESQANEINVLTVALVNQDREKTSEKRSPGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSRISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKFCAFEGIKTV", "length": 623, "header": "tr|E1BXD5-1|E1BXD5_CHICK Isoform 1 of Ecto-NOX disulfide-thiol exchanger 1 OS=Gallus gallus OX=9031 GN=ENOX1 PE=3 SV=2 CANONICAL=E1BXD5-1" }, "locus": { "chromosome": "1", "start_pos": 166813118, "end_pos": 166671878, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007872.1", "url": "https://www.ensembl.org/id/ENSGALT00010007872.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004726.1", "url": "https://www.ensembl.org/id/ENSGALP00010004726.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 86, "start_aa": "Thr", "end_pos": 86, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr86", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M9Z5-1", "protein_name": "Ecto-NOX disulfide-thiol exchanger 1 isoform X1", "gene_name": "Enox1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVDAAVFQSIAPCSQELPQMMAAAADGLGSIALDTTQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESVDRGHILEIRASEGESLPPLLSLEAQTKAAALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLAIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKDLVETNGHSHEDANEINVLTVALVNQDRENNSEKRIQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT", "length": 673 }, "evidence": [ { "id": "E1BXD5", "url": "https://omabrowser.org/oma/group/E1BXD5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZYM3-1", "protein_name": "Ecto-NOX disulfide-thiol exchanger 1", "gene_name": "Enox1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDAAGFESIAQCPQELHQMMAAAADGLGSIALDTTQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESEADTEDCAGDMADPGLHSAALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLAIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKDLVETNGHSHEDANEINVLTVALVNQDRENNTEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISASEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT", "length": 662 }, "evidence": [ { "id": "E1BXD5", "url": "https://omabrowser.org/oma/group/E1BXD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHR2-1", "protein_name": "Ecto-NOX disulfide-thiol exchanger 1", "gene_name": "Enox1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDAAGFESVAQCPRELHQMMAAAADGLGSIALDTTQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPGLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLADKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLAIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKDLVETNGHSHEDANEINVLTVALVNQDRENNTEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT", "length": 643 }, "evidence": [ { "id": "E1BXD5", "url": "https://omabrowser.org/oma/group/E1BXD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TC92-1", "protein_name": "Ecto-NOX disulfide-thiol exchanger 1", "gene_name": "ENOX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDAGGVENITQLPQELPQMMAAAADGLGSIAIDTTQLNMSVTDPTAWATAMNNLGMVPVGLPGQQLVSDSICVPGFDPSLNMMTGITPINPMIPGLGLVPPPPPTEVAVVKEIIHCKSCTLFPQNPNLPPPSTRERPPGCKTVFVGGLPENATEEIIQEVFEQCGDITAIRKSKKNFCHIRFAEEFMVDKAIYLSGYRMRLGSSTDKKDSGRLHVDFAQARDDFYEWECKQRMRAREERHRRKLEEDRLRPPSPPAIMHYSEHEAALLAEKLKDDSKFSEAITVLLSWIERGEVNRRSANQFYSMVQSANSHVRRLMNEKATHEQEMEEAKENFKNALTGILTQFEQIVAVFNASTRQKAWDHFSKAQRKNIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKEENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQEQLKGTKELVETNGHSHEDSNEINVLTVALVNQDRENNIEKRSQGLKSEKEALLIGIISTFLHVHPFGANIEYLWSYMQQLDSKISANEIEMLLMRLPRMFKQEFTGVGATLEKRWKLCAFEGIKTT", "length": 643 }, "evidence": [ { "id": "E1BXD5", "url": "https://omabrowser.org/oma/group/E1BXD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "NADH dehydrogenase activity", "id": "GO:0003954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003954", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ultradian rhythm", "id": "GO:0007624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007624", "evidence": [ { "database": "UniProtKB", "id": "E1BXD5", "url": "https://www.uniprot.org/uniprotkb/E1BXD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BXD5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 623, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BXD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BXD5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 86 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 413, "end_pos": 415 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXF4-1", "uniprot_ac": "E1BXF4", "uniprot_id": "E1BXF4_CHICK", "mass": { "chemical_mass": 37874.0, "monoisotopic_mass": 37874.0 }, "refseq": { "ac": "XP_040528261", "name": "reticulocalbin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528261" }, "gene_names": [ { "name": "RCN1", "type": "recommended", "evidence": [ { "id": "E1BXF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXF4" } ] }, { "name": "RCN1", "type": "synonym", "evidence": [ { "id": "XP_040528261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528261" } ] } ], "protein_names": [ { "name": "Reticulocalbin 1", "type": "synonym", "evidence": [ { "id": "E1BXF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXF4/entry#names_and_taxonomy" } ] }, { "name": "reticulocalbin-1", "type": "synonym", "evidence": [ { "id": "XP_040528261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528261" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040528261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528261" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXF4", "url": "https://www.uniprot.org/uniprotkb/E1BXF4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RCN1", "url": "https://www.uniprot.org/uniprotkb/E1BXF4", "locus": { "chromosome": "5", "start_pos": 5532080, "end_pos": 5523067, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023668", "url": "https://www.ensembl.org/id/ENSGALG00010023668" } ] } } ], "crossref": [ { "id": "E1BXF4", "url": "https://alphafold.ebi.ac.uk/entry/E1BXF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012121", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012121", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16229", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16229", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428602", "url": "https://www.ncbi.nlm.nih.gov/gene/428602", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428602", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428602", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DRPGFQY", "url": "https://omabrowser.org/oma/group/DRPGFQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTV7", "url": "https://www.orthodb.org/?gene=A0A8V0ZTV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXF4", "url": "https://www.orthodb.org/?gene=E1BXF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10827:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10827:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1BXF4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1BXF4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-381426", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8957275", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040528261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528261", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXF4", "url": "https://www.uniprot.org/uniprotkb/E1BXF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXF4-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGAGRCPAALLLLALPLLALPGGLGKPTAWQERARPGTAQQHEDAPSFQYDHEAFLGKEEARSFDQLSPEESQERLGKIVDRIDENKDGYLTTEELKNWIKRVQKRYIYENVAKVWKDYDTNKDNKITWEEYKQATYGYYLENPEEFQDATDRHSFKKMLPRDERRFKTADLDGDSAATREEFTAFLHPEEFEHMKDIVVLETLEDIDKNEDGFVDQDEYIADMFANEEGGPEPDWVTTEREQFSDFRDLNKDGKMDKEEIQHWILPQDYDHALAEARHLVYESDVDKDQKLTKEEVLDNWNMFVGSQATNYGEDLTRNHDEL", "length": 325, "header": "tr|E1BXF4-1|E1BXF4_CHICK Isoform 1 of Reticulocalbin 1 OS=Gallus gallus OX=9031 GN=RCN1 PE=1 SV=3 CANONICAL=E1BXF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTV7-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF4/entry#A0A8V0ZTV7-1", "sequence": { "sequence": "MGGAGGLGKPTAWQERARPGTAQQHEDAPSFQYDHEAFLGKEEARSFDQLSPEESQERLGKIVDRIDENKDGYLTTEELKNWIKRVQKRYIYENVAKVWKDYDTNKDNKITWEEYKQATYGYYLENPEEFQDATDRHSFKKMLPRDERRFKTADLDGDSAATREEFTAFLHPEEFEHMKDIVVLETLEDIDKNEDGFVDQDEYIADMFANEEGGPEPDWVTTEREQFSDFRDLNKDGKMDKEEIQHWILPQDYDHALAEARHLVYESDVDKDQKLTKEEVLDNWNMFVGSQATNYGEDLTRNHDEL", "length": 306, "header": "tr|A0A8V0ZTV7-1|A0A8V0ZTV7_CHICK Computationally mapped isoform of Reticulocalbin 1 OS=Gallus gallus OX=9031 GN=RCN1 PE=1 SV=1 CANONICAL=E1BXF4-1" }, "locus": { "chromosome": "5", "start_pos": 5530310, "end_pos": 5523116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057659.1", "url": "https://www.ensembl.org/id/ENSGALT00010057659.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035010.1", "url": "https://www.ensembl.org/id/ENSGALP00010035010.1" } ] } }, { "isoform_ac": "E1BXF4-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF4/entry#E1BXF4-1", "sequence": { "sequence": "MGGGAGRCPAALLLLALPLLALPGGLGKPTAWQERARPGTAQQHEDAPSFQYDHEAFLGKEEARSFDQLSPEESQERLGKIVDRIDENKDGYLTTEELKNWIKRVQKRYIYENVAKVWKDYDTNKDNKITWEEYKQATYGYYLENPEEFQDATDRHSFKKMLPRDERRFKTADLDGDSAATREEFTAFLHPEEFEHMKDIVVLETLEDIDKNEDGFVDQDEYIADMFANEEGGPEPDWVTTEREQFSDFRDLNKDGKMDKEEIQHWILPQDYDHALAEARHLVYESDVDKDQKLTKEEVLDNWNMFVGSQATNYGEDLTRNHDEL", "length": 325, "header": "tr|E1BXF4-1|E1BXF4_CHICK Isoform 1 of Reticulocalbin 1 OS=Gallus gallus OX=9031 GN=RCN1 PE=1 SV=3 CANONICAL=E1BXF4-1" }, "locus": { "chromosome": "5", "start_pos": 5530310, "end_pos": 5523116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057669.1", "url": "https://www.ensembl.org/id/ENSGALT00010057669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035015.1", "url": "https://www.ensembl.org/id/ENSGALP00010035015.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428602", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428602", "resource": "KEGG Pathway" }, { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUB0-1", "protein_name": "Reticulocalbin-1", "gene_name": "Rcn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGGRLGLALGLLLALVLALRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKVWIKRVQKRYIYDNVAKVWKDYDRDKDEKISWEEYKQATYGYYLGNPAEFQDSSDHHTFKKMLPRDERRFKASDLDGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL", "length": 325 }, "evidence": [ { "id": "E1BXF4", "url": "https://omabrowser.org/oma/group/E1BXF4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R369-1", "protein_name": "Reticulocalbin-1", "gene_name": "rcn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEVSTYLWLLSLCTSLVQGKPTLRKERVHHEPELSRQTHEDNQSYQYDHEAFLGKEEATTFDQLTPEESKARLGKIVERIDSNVDGFITTDELKAWIKRVQKRYVYENVAKVWTDYDLNKDNKISWDEYKQATYGYYLANPEEFEDATDQFSFKKMLPRDERRFKTADLDGNLAADKEEFTAFLHPEEFAHMQEIVVLETLEDIDKNGDGHVDEDEYIADMFAHEDAGPEPDWVRTERDQFSDFRDLNKDGKMDLEEIRHWILPQDYDHAQAEARHLVYESDTDKDQMLSKEEILENWNMFVGSQATNYGEDLTRNHDEL", "length": 320 }, "evidence": [ { "id": "E1BXF4", "url": "https://omabrowser.org/oma/group/E1BXF4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3N2L2-1", "protein_name": "Reticulocalbin-1", "gene_name": "RCN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARGGRGRHLGLALGLLLALLLAPPALWAKPTVRKERVVRPDSDLGERPAEDNQSFQYDHEAFLGKEDSKTFDQLTSEESKERLGKIVDRIDSDGDGFVTTEELKTWIKRVQKRYIYDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPTEFQDTSDHHTFKKMLPRDERRFKAADLDSDQTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEESGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL", "length": 331 }, "evidence": [ { "id": "E1BXF4", "url": "https://omabrowser.org/oma/group/E1BXF4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q05186-1", "protein_name": "Reticulocalbin-1", "gene_name": "Rcn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGGRLGLALGLLLALVLALRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLSPDESKERLGKIVDRIDSDGDGLVTTEELKLWIKRVQKRYIYDNVAKVWKDYDRDKDEKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKASDLDGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEDNGPEPDWVLSEREQFNDFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEMLTKEEILDNWNMFVGSQATNYGEDLTKNHDEL", "length": 325 }, "evidence": [ { "id": "E1BXF4", "url": "https://omabrowser.org/oma/group/E1BXF4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q15293-1", "protein_name": "Reticulocalbin-1", "gene_name": "RCN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGGRGRRLGLALGLLLALVLAPRVLRAKPTVRKERVVRPDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLTPDESKERLGKIVDRIDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESDKNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDEL", "length": 331 }, "evidence": [ { "id": "E1BXF4", "url": "https://omabrowser.org/oma/group/E1BXF4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BXF4", "url": "https://www.uniprot.org/uniprotkb/E1BXF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E1BXF4", "url": "https://www.uniprot.org/uniprotkb/E1BXF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BXF4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 325, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BXF4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BXF4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BXF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXF4" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 108, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXH7-1", "uniprot_ac": "E1BXH7", "uniprot_id": "E1BXH7_CHICK", "mass": { "chemical_mass": 50462.0, "monoisotopic_mass": 50462.0 }, "refseq": { "ac": "XP_421418", "name": "probable sodium-coupled neutral amino acid transporter 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421418" }, "gene_names": [ { "name": "SLC38A6", "type": "recommended", "evidence": [ { "id": "E1BXH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ] }, { "name": "SLC38A6", "type": "synonym", "evidence": [ { "id": "XP_421418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421418" } ] } ], "protein_names": [ { "name": "Solute carrier family 38 member 6", "type": "synonym", "evidence": [ { "id": "E1BXH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXH7/entry#names_and_taxonomy" } ] }, { "name": "probable sodium-coupled neutral amino acid transporter 6", "type": "synonym", "evidence": [ { "id": "XP_421418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421418" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421418" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC38A6", "url": "https://www.uniprot.org/uniprotkb/E1BXH7", "locus": { "chromosome": "5", "start_pos": 53722676, "end_pos": 53762088, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017818", "url": "https://www.ensembl.org/id/ENSGALG00010017818" } ] } } ], "crossref": [ { "id": "E1BXH7", "url": "https://alphafold.ebi.ac.uk/entry/E1BXH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011893", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011893", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423519", "url": "https://www.ncbi.nlm.nih.gov/gene/423519", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423519", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423519", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KARMQNV", "url": "https://omabrowser.org/oma/group/KARMQNV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3R1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXH7", "url": "https://www.orthodb.org/?gene=E1BXH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BXH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALPRGAQRGWYLSARRQRDCGQGEDGDDDSEEDGETAPLLPAASGRGSSQRGSSFGLSVFNLMNAIMGSGILGLSYAMAGTGVLGFSALLLMVASLASYSVFLLLSMCTQTAVTSYEDLGLFAFGSAGKVLVATTIIIQNIGAMSSYLLIVKSELPGAVAGFLSGDGSGSWYLDGRLLLLITSVCIVFPLALLPKIGFLGYTSSLSFFFMVYFALVIMIKKWSIPCPLPLGSAIETLQVSNSTADCKAKLFHLSKESAYAIPTMAFSFLCHTSVLPIYCELQSPSKSRMQNVAVTGIGLSFIIYFMSALFGYLTFYDKVDSELLRGYSRYLPHDTVIMTVKLAILFSVLLTVPLIHFPARKAVFLVFFSHLPVSWICHILVTLVLNAIIVLFAMYVPDIKNVFGVVGSTTSTCLLFVYPGLFYLKLSREDFLSPHKLGACALVIFGICVGLLSLVLIILNWINQ", "length": 466, "header": "tr|E1BXH7-1|E1BXH7_CHICK Isoform 1 of Solute carrier family 38 member 6 OS=Gallus gallus OX=9031 GN=SLC38A6 PE=3 SV=3 CANONICAL=E1BXH7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3R1-1", "url": "https://www.uniprot.org/uniprotkb/E1BXH7/entry#A0A8V0Z3R1-1", "sequence": { "sequence": "MEALPRGAQRGWYLSARRQRDCGQGEDGDDDSEEDGETAPLLPAASGRGSSQRGSSFGLSVFNLMNAIMGSGILGLSYAMAGTGVLGFSALLLMVASLASYSVFLLLSMCTQTDLLLLSSPIE", "length": 123, "header": "tr|A0A8V0Z3R1-1|A0A8V0Z3R1_CHICK Computationally mapped isoform of Solute carrier family 38 member 6 OS=Gallus gallus OX=9031 GN=SLC38A6 PE=3 SV=1 CANONICAL=E1BXH7-1" }, "locus": { "chromosome": "5", "start_pos": 53762046, "end_pos": 53760420, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043062.1", "url": "https://www.ensembl.org/id/ENSGALT00010043062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025552.1", "url": "https://www.ensembl.org/id/ENSGALP00010025552.1" } ] } }, { "isoform_ac": "E1BXH7-1", "url": "https://www.uniprot.org/uniprotkb/E1BXH7/entry#E1BXH7-1", "sequence": { "sequence": "MEALPRGAQRGWYLSARRQRDCGQGEDGDDDSEEDGETAPLLPAASGRGSSQRGSSFGLSVFNLMNAIMGSGILGLSYAMAGTGVLGFSALLLMVASLASYSVFLLLSMCTQTAVTSYEDLGLFAFGSAGKVLVATTIIIQNIGAMSSYLLIVKSELPGAVAGFLSGDGSGSWYLDGRLLLLITSVCIVFPLALLPKIGFLGYTSSLSFFFMVYFALVIMIKKWSIPCPLPLGSAIETLQVSNSTADCKAKLFHLSKESAYAIPTMAFSFLCHTSVLPIYCELQSPSKSRMQNVAVTGIGLSFIIYFMSALFGYLTFYDKVDSELLRGYSRYLPHDTVIMTVKLAILFSVLLTVPLIHFPARKAVFLVFFSHLPVSWICHILVTLVLNAIIVLFAMYVPDIKNVFGVVGSTTSTCLLFVYPGLFYLKLSREDFLSPHKLGACALVIFGICVGLLSLVLIILNWINQ", "length": 466, "header": "tr|E1BXH7-1|E1BXH7_CHICK Isoform 1 of Solute carrier family 38 member 6 OS=Gallus gallus OX=9031 GN=SLC38A6 PE=3 SV=3 CANONICAL=E1BXH7-1" }, "locus": { "chromosome": "5", "start_pos": 53762046, "end_pos": 53730950, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043070.1", "url": "https://www.ensembl.org/id/ENSGALT00010043070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025560.1", "url": "https://www.ensembl.org/id/ENSGALP00010025560.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423519", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423519", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N3L7-1", "protein_name": "Solute carrier family 38 member 6", "gene_name": "SLC38A6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEVPAGVINAEPGWFVSTQEPEEAEAEESSPLLSNEVHTQRSRGASFGFSVFNLMNAIMGSGILGLAYVMAHTGILGFSFLLLIVALLASYSVHLLLSLCIQTAVTSYEDLGLFAFGLPGKVMVASTIIIQNIGAMSSYLLIIKTELPATISEFLSGDYSGSWYLDGDTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMVFFALVVIIKKWSIPCPLTLNYVEQYFQISSATDDCKPKLFHFSKESAYAIPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDSVASELLQGYSKYLPHDVVIMTVKLCILFSVLLTVPLIHFPARKALMMMFFSNFPFSWIRHSLITLALNIVIVLLAIYVPDIRNVFGIVGSSTSTCLIFVFPGLFYLKMSREDFLSWKKLGAFVLLIFGILVGNFSLALIIFNWINK", "length": 456 }, "evidence": [ { "id": "E1BXH7", "url": "https://omabrowser.org/oma/group/E1BXH7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A480Y8S6-1", "protein_name": "Solute carrier family 38 member 6", "gene_name": "SLC38A6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAPWGTISAEPGWFVSTQQIEEAEAEELSPLLSNELHRQGSPGVSFGFSVFNLMNAIMGSGILGLAYVMAHTGILGFSLLLLMVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKVVVAGTIIIQNIGAMSSYLLIIKTELPAAISEFLSGDHSGSWYLDGETLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMVFFAIVIIIKKWSIPCPLTLNYIERYFQISNATDDCKPKLFHFSKESAYAIPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDNVASELLQGYSKYLPHDVVVMTVKLCILFAVLLTVPLIHFPARKALMMIFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVIGSSTSTCLIFVFPGLFYLRLSREDFLSWKKLGAFVLLIFGILVGNFSLALVIFNWINK", "length": 456 }, "evidence": [ { "id": "E1BXH7", "url": "https://omabrowser.org/oma/group/E1BXH7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3UVW3-1", "protein_name": "Solute carrier family 38 member 6", "gene_name": "Slc38a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQASRHSIQAEPGWYVSAQQPEEAVAADEWSPLLSNEPHRQGSSGASFGLSVFNVMNAIMGSGILGLAYVMANTGILGFSFLLLFVALLASYSVHLLLAMCIHTAVTSYEDLGLFAFGLPGKVVVAGTIIIQNIGAMSSYLLIIKTELPAAISEFLPSDHSGSWYLDGQMLLIIICVGIVFPLSLLPKIGFLGYTSSLSFFFMVFFALVVVIKKWAVPCPVTLDCINEVFQISNATDDCKPKLFHFSKESVYAIPTMAFSFLCHTSVLPIYCELQSPSKKRMQNVTNTAIALSFLVYFVSALFGYLTFYDKVESELLQGYSKYLPHDVIVMAVKLCILFAVLLTAPLIHFPARKALMMILFSNYPFSWIRHSLTTAALNAIIVVLAIYVPDIRNVFGVVGASTSTCLIFVFPGLFYLKLSREDFLSWKKLGALFLLLTGAVVGSFSLVLIIFDWVNK", "length": 457 }, "evidence": [ { "id": "E1BXH7", "url": "https://omabrowser.org/oma/group/E1BXH7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38176-1", "protein_name": "Vacuolar amino acid transporter 5", "gene_name": "AVT5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVNRHQLERGQVYFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIENFRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH", "length": 459 }, "evidence": [ { "id": "E1BXH7", "url": "https://omabrowser.org/oma/group/E1BXH7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6WWW3-1", "protein_name": "Solute carrier family 38 member 6", "gene_name": "Slc38a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQASRYSIEAEPGWYVSVQQPEEAVAAEEWSPLLSNEPRRQGSSGASFGLSVFNVMNAIMGSGILGLAYVMANTGILGFSFLLLLVALLASYSVHLLLAMCIHTAVTSYEDLGLFAFGLPGKVVVAGTIIIQNIGAMSSYLLIIKTELPAAISEVLPSDHSGAWYLDGQMLLIIICVGIVFPLSLLPKIGFLGYTSSLSFFFMVFFALVVVIKKWAVPCPLTLNCINAVFQISNATDDCKPKLFHFSKESVYAIPTMAFSFLCHTSVLPIYCELRSPSKKRMQNVTNTAIALSFLVYFVSALFGYLTFYDKVESELLQGYSKYLPHDAAVMAVKLCILFAVLLTVPLIHFPARKALMMILFSNYPFSWIRHSLTTLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFVFPGLFYLKLSREDFLSWKKLGALSLLSTGTVVGSFSLVLIILDWVNK", "length": 457 }, "evidence": [ { "id": "E1BXH7", "url": "https://omabrowser.org/oma/group/E1BXH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IZM9-1", "protein_name": "Solute carrier family 38 member 6", "gene_name": "SLC38A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEASWGSFNAERGWYVSVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWINK", "length": 456 }, "evidence": [ { "id": "E1BXH7", "url": "https://omabrowser.org/oma/group/E1BXH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LI61-1", "protein_name": "Amino acid transporter AVT6A", "gene_name": "AVT6A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTVVGDVAPIPRRNSSTCSNDIAAPLLPECHGDEVAHDEFNGASFSGAVFNLATTIIGAGIMALPATMKILGLGLGITMIVVMAFLTDASIEFLLRFSKAGKNRSYGGLMGGSFGNPGRILLQVAVLVNNIGVLIVYMIIIGDVLAGKTEDGIHHFGVLEGWFGHHWWNGRAAILLITTLGVFAPLACFKRIDSLKFTSALSVALAVVFLIITAGISIMKLISGGVAMPRLLPDVTDLTSFWNLFTVVPVLVTAFICHYNVHSIQNELEDPSQIRPVVRSALMLCSSVYIMTSIFGFLLFGDDTLDDVLANFDTDLGIPFGSILNDAVRVSYALHLMLVFPIVFYPLRINIDGLLFPSARSLSTSNVRFGCLTAGLISVIFLGANFIPSIWDAFQFTGATAAVCLGFIFPASIILKDRHDKATNRDTTLAIFMIVLAVLSNAIAIYSDAYALFKKNAPRE", "length": 460 }, "evidence": [ { "id": "E1BXH7", "url": "https://omabrowser.org/oma/group/E1BXH7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "glutamine transport", "id": "GO:0006868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006868", "evidence": [ { "database": "UniProtKB", "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ], "pmid": "" }, { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ], "pmid": "" }, { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "L-glutamine transmembrane transporter activity", "id": "GO:0015186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015186", "evidence": [ { "database": "UniProtKB", "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ], "pmid": "" }, { "name": "L-glutamate transmembrane transporter activity", "id": "GO:0005313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005313", "evidence": [ { "database": "UniProtKB", "id": "E1BXH7", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BXH7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 466, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BXH7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BXH7" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BXH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXH7" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 462, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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The reference sequence was derived from JAENSK010000375.1. 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"XP_003640402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640402", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BXX3", "url": "https://www.uniprot.org/uniprotkb/E1BXX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXX3-1", "url": "https://www.uniprot.org/uniprotkb/E1BXX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFTSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370, "header": "tr|E1BXX3-1|E1BXX3_CHICK Isoform 1 of G protein-coupled receptor 85 OS=Gallus gallus OX=9031 GN=GPR85 PE=4 SV=1 CANONICAL=E1BXX3-1" }, "isoforms": [ { "isoform_ac": "E1BXX3-1", "url": 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"glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 252, "start_aa": "Thr", "end_pos": 252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr252", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417775", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VYW7-1", "protein_name": "G protein-coupled receptor 85", "gene_name": "GPR85", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "E1BXX3", "url": "https://omabrowser.org/oma/group/E1BXX3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GW31-1", "protein_name": "Probable G-protein coupled receptor 85", "gene_name": "Gpr85", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSSWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "E1BXX3", "url": "https://omabrowser.org/oma/group/E1BXX3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3N1Y5-1", "protein_name": "G protein-coupled receptor 85", "gene_name": "GPR85", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTSRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "E1BXX3", "url": "https://omabrowser.org/oma/group/E1BXX3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P60893-1", "protein_name": "Probable G protein-coupled receptor 85", "gene_name": "GPR85", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "E1BXX3", "url": "https://omabrowser.org/oma/group/E1BXX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P60894-1", "protein_name": "Probable G protein-coupled receptor 85", "gene_name": "Gpr85", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "E1BXX3", "url": "https://omabrowser.org/oma/group/E1BXX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P60895-1", "protein_name": "Probable G protein-coupled receptor 85", "gene_name": "Gpr85", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI", "length": 370 }, "evidence": [ { "id": "E1BXX3", "url": "https://omabrowser.org/oma/group/E1BXX3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "E1BXX3", "url": "https://www.uniprot.org/uniprotkb/E1BXX3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BXX3", "url": "https://www.uniprot.org/uniprotkb/E1BXX3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BXX3", "url": "https://www.uniprot.org/uniprotkb/E1BXX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXX3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 339, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 252 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXZ2-1", "uniprot_ac": "E1BXZ2", "uniprot_id": "E1BXZ2_CHICK", "mass": { "chemical_mass": 172559.0, "monoisotopic_mass": 172559.0 }, "refseq": { "ac": "XP_004942218", "name": "zinc finger protein 518A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942218" }, "gene_names": [ { "name": "ZNF518A", "type": "recommended", "evidence": [ { "id": "E1BXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2" } ] }, { "name": "ZNF518A", "type": "synonym", "evidence": [ { "id": "XP_004942218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942218" } ] } ], "protein_names": [ { "name": "Zinc finger protein 518A", "type": "synonym", "evidence": [ { "id": "E1BXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 518A", "type": "synonym", "evidence": [ { "id": "XP_004942218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942218" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942218" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXZ2", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF518A", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2", "locus": { "chromosome": "6", "start_pos": 21927539, "end_pos": 21816806, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021621", "url": "https://www.ensembl.org/id/ENSGALG00010021621" } ] } } ], "crossref": [ { "id": "ENSGALG00000006966", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006966", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428964", "url": "https://www.ncbi.nlm.nih.gov/gene/428964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428964", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428964", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCVEECM", "url": "https://omabrowser.org/oma/group/SCVEECM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BXZ2", "url": "https://www.orthodb.org/?gene=E1BXZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23224", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23224", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942218", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BXZ2", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXZ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSEQDQFSHDKKQINLLKHDAANNLCMDTSLENALVNDPLNMTTRPAVLNVNFSCELKNVKIDLPKVNIPNEVLMKHEIDKFRKLFQCKQQTARKSLTLEKVNVSSPDCSEGSQVQNKIEVQFGKGLKTTAKILHFTCTKCEDNVRYSPNDLQKHFQLLHSGELPVYPCEMCNFSANDFQAFNQHRRTHRSTLVKCELCLDEQMYTLLDLTKHFTSKHCVNGHFQCEKCGFSTQDVGTFVQHIHRHNGITYECGKCHHISYTEEEFQRHNLVHSSLILFRCQFCSYSTPRKDYILRHLIALHRDHLCAKEKLERDKFEKRILKTPAALKLVLRRYKTGTSKKPLWRRKKIIGASDKTGEKNSQVLRIVNKIQPKLDELNQYMKVVEANEEKDQIPCTEKNFTGGIHAATTAQYNKADDGMRFSLGSLKNTVHGPAVLMIKNNKISVPANYSAKFMGFKIVDGKQHIVIKLLPTNKQNLHLLGQKADPIKDGSTPPLLQTADPCSLSSGAIPHVTDQSTFKNKSIHPLTSVFSSAPHSGKAKVEKQNNSLLYGRSVSQTVAPSNVAVGKNSYNLPMKLGSPVSPHDEVTKIGTQNNISWRNYSPPSHPQVLSPPVTNTLCYDPWKIPFFPELKIQNGGLNNNHRTNNLYYSPSVDSSNEGLLSFHNYSKTDTLDNQCGVWMSTDDKSKEFISSQTVNFQNSDESASSYSESVKDLKPENTVSAQSNIKTYEHINTKNNGMSPSSQSKCGIDREYFVEDQHNGQQYLDTNLYQDLMSTAEEFQENGSDCVNSVLMPKITSVFSLQSEQAANYLSPEINQLLQDVLKVNATPQQESHCKLNNCVELHSDKLLSSQEKGNRAFTRSKNSATTCSFQRPSTNVDFHLCKRELNTRCSMHEGMHCGEERKTPRTYLDSQGMEMVCRTADGASLKDDTDAIITQQLVKDKMQSTSSNPTSFSPILQEQKKTLLVQPPPSRFFVPLQLANQPGLQVVSGKPHLSPSSSDGHATKGVPTSFALNKGPGMILTFSGSIGAVANVPSDSPQVLGRVASREYGKITIPASKVEGKNDSFRSVRSCCSRRTCSAANDSLNSMSSKGPLVVTNLAESSVKGISSVKASSEHQDAVFGSEESTEQKEMKQKQHVYAFLPDGQQAVFLKYMTPNKPVVHKHSVFQDNAHYQNCQPKKTGVMQQKLLLKIKTSDMLAETNQSVNNSVPSVQLDSVQSLTPALAQKQTDLTSNDALILPGRLMPANASLASSNPACCIPSVEPVYCTRTAGSWLQKGFVESTQIITANRNNFGSQKSSWSTQNRIAKVKPRLKQSGPKSSETVLLQRNKNFKRKNKDNCKEPPRKKVTLHRKCKEKNRGEVISESGGHYKQRASKDTVRTLKLLPFNSKQLVKCPRRNQPVVVLNHPDADVPEVVNVMKTIAKFKGHVLKVSLSKRTIEALEPAFCNHLDITTDNLFQKRHRTIKPISPVKERFVLKLTLKKTSKNNYQIVKTTSDNTLKAKFSCWFCGRIFDNQDNWVGHGQRHLMEATRDWNLLV", "length": 1540, "header": "tr|E1BXZ2-1|E1BXZ2_CHICK Isoform 1 of Zinc finger protein 518A OS=Gallus gallus OX=9031 GN=ZNF518A PE=4 SV=5 CANONICAL=E1BXZ2-1" }, "isoforms": [ { "isoform_ac": "E1BXZ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2/entry#E1BXZ2-1", "sequence": { "sequence": "MPSEQDQFSHDKKQINLLKHDAANNLCMDTSLENALVNDPLNMTTRPAVLNVNFSCELKNVKIDLPKVNIPNEVLMKHEIDKFRKLFQCKQQTARKSLTLEKVNVSSPDCSEGSQVQNKIEVQFGKGLKTTAKILHFTCTKCEDNVRYSPNDLQKHFQLLHSGELPVYPCEMCNFSANDFQAFNQHRRTHRSTLVKCELCLDEQMYTLLDLTKHFTSKHCVNGHFQCEKCGFSTQDVGTFVQHIHRHNGITYECGKCHHISYTEEEFQRHNLVHSSLILFRCQFCSYSTPRKDYILRHLIALHRDHLCAKEKLERDKFEKRILKTPAALKLVLRRYKTGTSKKPLWRRKKIIGASDKTGEKNSQVLRIVNKIQPKLDELNQYMKVVEANEEKDQIPCTEKNFTGGIHAATTAQYNKADDGMRFSLGSLKNTVHGPAVLMIKNNKISVPANYSAKFMGFKIVDGKQHIVIKLLPTNKQNLHLLGQKADPIKDGSTPPLLQTADPCSLSSGAIPHVTDQSTFKNKSIHPLTSVFSSAPHSGKAKVEKQNNSLLYGRSVSQTVAPSNVAVGKNSYNLPMKLGSPVSPHDEVTKIGTQNNISWRNYSPPSHPQVLSPPVTNTLCYDPWKIPFFPELKIQNGGLNNNHRTNNLYYSPSVDSSNEGLLSFHNYSKTDTLDNQCGVWMSTDDKSKEFISSQTVNFQNSDESASSYSESVKDLKPENTVSAQSNIKTYEHINTKNNGMSPSSQSKCGIDREYFVEDQHNGQQYLDTNLYQDLMSTAEEFQENGSDCVNSVLMPKITSVFSLQSEQAANYLSPEINQLLQDVLKVNATPQQESHCKLNNCVELHSDKLLSSQEKGNRAFTRSKNSATTCSFQRPSTNVDFHLCKRELNTRCSMHEGMHCGEERKTPRTYLDSQGMEMVCRTADGASLKDDTDAIITQQLVKDKMQSTSSNPTSFSPILQEQKKTLLVQPPPSRFFVPLQLANQPGLQVVSGKPHLSPSSSDGHATKGVPTSFALNKGPGMILTFSGSIGAVANVPSDSPQVLGRVASREYGKITIPASKVEGKNDSFRSVRSCCSRRTCSAANDSLNSMSSKGPLVVTNLAESSVKGISSVKASSEHQDAVFGSEESTEQKEMKQKQHVYAFLPDGQQAVFLKYMTPNKPVVHKHSVFQDNAHYQNCQPKKTGVMQQKLLLKIKTSDMLAETNQSVNNSVPSVQLDSVQSLTPALAQKQTDLTSNDALILPGRLMPANASLASSNPACCIPSVEPVYCTRTAGSWLQKGFVESTQIITANRNNFGSQKSSWSTQNRIAKVKPRLKQSGPKSSETVLLQRNKNFKRKNKDNCKEPPRKKVTLHRKCKEKNRGEVISESGGHYKQRASKDTVRTLKLLPFNSKQLVKCPRRNQPVVVLNHPDADVPEVVNVMKTIAKFKGHVLKVSLSKRTIEALEPAFCNHLDITTDNLFQKRHRTIKPISPVKERFVLKLTLKKTSKNNYQIVKTTSDNTLKAKFSCWFCGRIFDNQDNWVGHGQRHLMEATRDWNLLV", "length": 1540, "header": "tr|E1BXZ2-1|E1BXZ2_CHICK Isoform 1 of Zinc finger protein 518A OS=Gallus gallus OX=9031 GN=ZNF518A PE=4 SV=5 CANONICAL=E1BXZ2-1" }, "locus": { "chromosome": "6", "start_pos": 21880439, "end_pos": 21875820, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052508.1", "url": "https://www.ensembl.org/id/ENSGALT00010052508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031415.1", "url": "https://www.ensembl.org/id/ENSGALP00010031415.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428964", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428964", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RRF6-1", "protein_name": "Zinc finger protein 518A", "gene_name": "Znf518a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFEQTQLFCDEKPTILKKLDTRNEIADTIRSVSTSKISETSFQYVLKDVNICLPKINIPNEILMKHEVEKYRLLFQSKPQTARKSISVKTVSCAEECVLLCKSERAEDETVNMSAKILNFSCSKCQDSTQYSPNDLQKHFEMWHHGELPSFPCEMCSFSASDFQIFKQHRKTHRNTFVKCDICNSERSYTLLDLTKHFTSKHCVNGNFQCEECRFFTQDVGTFVQHIHRHKEVHYKCGKCHHLCFTKGELQKHLRVHSGTLPFTCHYCSYGAIHKDQLIRHVITLHKEHLYAKEKLERDQYDKRVAKTTTTGLKLILKRYKIGPTKTFWKRKTITSGNDESIGKNAQAFNIVSKTQTKSEDQSQEQVNGEKGEKQHCENGDKPVESESEKATVLSTGQYNKADEGASTTSSSVLSAVQGPTVLLVRNNKITIPANYSAKFMGFKMVDGRQHIVIKLLPANKQILPSPVLQSNTEKNSTANLSPQAVANTGFATGLTTKVNDTDFVKAAPPACSSPVLARKVISEKEAAFISEKNNTLQMVDDSKSLSSLPTTSTTSVRVTTKVEARDNVDLWENDSPQSHPDASDTSISSPDKVSLTPKPNAYSSGDMHNYCINYVNSELPAESSNSFEFSNQGSLPFHNYSKVNNKRRRFSRATLCENLQKESPNKTVTQQSTSDSDTASPLLRKESSNSDNLFASINPLNGTLKIKTEIEEPYNLEETQNFNEQSLFTNENQNLLNVTEEPKWNDIPSAGSPMMPRITSVFSLQSEQASEFLTPEVNQLLQDTLKPKSDIKEDSNNIPSKNLPFDCDQTLKKSEEVVIKSSKDFQMQDDIPVPSASVGVNVPANDLNSKCNGQEKQGLSVLQDVRDSEVTTKIPNIITLLKTQSDAIITQQLVKDKLRTTTQNSGPVYVQNPFLTSEQKNPVFVQTPKGFIIPLHVANKPGLHVFSGRPVPLVNTRSVPATLLVNKKPGMLLATNNGKPESVPTVKTENVHSYGTVTKEPCKTPFLKAEHNNSCLTPGLCSSIGNCVNMKTCSENTLPLKGSYIIKTSVNSSVKAVPNILPEQQGPKMNILDTVKQQNENLPKASLYTLMPDGKQAVFFKCVMPNNTKLLKPKLVQSSTYQHIQPKRPAGAPQKILVKIFNPVLSMSAFNNLSASNSASSFQKEIVPSKPTVHGEQKEPETSRNALPVLVHGLMPANETVHSSTTACPGSSEEPVYISERSETRVLRGKANCAVERNFNKRKTCKNKFAKIKTRIDQDSETAFVSRNRSCKRKYIDNYQEPPRKKSTLNRKGKERASAEDVQEAFGFSRPRLPKDSSRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADTPEVERVMKTIAKFNGHVLKVSLSQTTINALLKPVSNTSETTYNDFSKRQKMLKPVNSVKERFVLKLTLKKTSKNNYQIVKTTSEDVLKSQFNCWFCGRVFDNQDVWAGHGQRHLVEATRDWNMLE", "length": 1478 }, "evidence": [ { "id": "E1BXZ2", "url": "https://omabrowser.org/oma/group/E1BXZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BG18-1", "protein_name": "Zinc finger protein 518A", "gene_name": "ZNF518A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSEQKHLFFDEKQNTLKKDYDVKNEVVDSLRSKISEPKFQNQLKPNISESSFHYGLKNVKIVLPKIHIPNEVLLKHEVDKYRKLFQHKPQTARKSINVKTVSSVEECMLLHQSERVDEGIKMSAKILNFSCLKCRDSTRYSPNDLQKHFQMWHHGELPSYPCEMCSFSANDFQVFKQHRRTHRITLVKCDICNNENLYTLLDLTKHFSSTHCVNGTFQCEKCEFSTQDVGTFVQHIHRHNEILYKCGKCHYICLTKGELQKHLYIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKYEKRMAKSSAGLKLILKRYKIGASRKTFWRRKKVNNASDRSIEKNTQVLKKVNRTQATSEDPGHLVQEHVNEEKHERLYCENNDKPAESELGKPTLVSTGQCNGAQEGSNSTSGFLKTAVQGPTVLMVKNNRITIPANYSAKFMGFKMVDGKQHIVIKLLPTTKPNPCVPGSQSGAARDSTAVLQPQTLDATAFLTGVPAELNDTVCMKAAPPFSSSSPVLSGKVISEKEMALLSQTSNIIPAVDDEKGVSPSPVESDLITASVNLTTKVETRDNVDLWGSHITQCHPEVLGTTVKSPDKVSCTAKPNSYNSGDMHNYCINYINSELPVESSSQGSLPFHNYSKVNNSNKRRRFSGTAMCENPQRESSSSKTVLSESVLSPVKKESSNPDSRLASISLLNSKDGTLKTQAEIEEQCVLEKGQNIDGQNLYTNENKSSESMTEKPKWDGISNVESPMMPRITSVFSLQSQQASELLPPELNQLLLDVLKAKPDVKQDSSNIPDKDVPLQCAQSFQEHGGENKIVESSKDLKVQGLFPIPSGSMGTSRPTDDLNLNCSGKEKQLLSQDVRDSKTPRSFGFGTLPKTQSDAIITQQLVKDKLRATTHSFYVHNPLNSEPRKAVFVQTPKCFLVPMHFTNKPRFHVSRRPLVNTQGIPAPLLLNKKPGMILTFNNGKLEGVSAVKTESAQACGTTTKEPCRAPFLKVEQNSNCLTPALCSSIGSCVSMKSSPENTLSFKGPYIIKTPANSSVKAVPTHIIPEHQGTKLNISDSVKPQNKIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTCLKNIQPKKPEGTPQKILLKIFNPVLNVTAASNLSVSNTGSSLQKDSVPSNQTTGQQKEPESSRDALPFLLDDMMPANEIVITSTATCPESSEEPICITDHSEARVLRCKTNCTIERNFNKKNTSKRKVSRIKNHVRSQDSETAFVSRSRNCKRKCRDSYQEPPRKKALHRKCKEKAKPESIPESFEFNRPRLSKDTVRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADSPEVVNVMKTVAKFNGRVLKVSLSKRTIDALLKPVCCNPSETTYDDFPKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENTLKAKFNCWFCGRVFDNQDAWAGHGQRHLMEATRDWNMLE", "length": 1482 }, "evidence": [ { "id": "E1BXZ2", "url": "https://omabrowser.org/oma/group/E1BXZ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SC29-1", "protein_name": "Zinc finger protein 518A", "gene_name": "ZNF518A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSEQKHLFFDEKQNTLKKDYDVKNEIVDTVRSVLKPKISESHFHYELKNVKIVLPRINIPNEVLLKHEVDKYRKLFQHKPQTARKSISIKTVNCIEECVLLHKSERVEEGIKMSAKILNFNCLKCRDSTRYSPNDLQKHFQMWHHGELPSYPCEMCSFSANDFQVFKQHRRTHRITLVKCDICNNENLYTLLDLTKHFSSTHCVNGNFQCEKCEFSTQDVGTFVQHIHRHNEVLYKCDKCHYICLTKGELQKHLHIHSGTFPFTCQYCSYGATRREHLIRHVITLHKEHLYAKEKLEKDKYEKRMAKTSTGLKLILKRYKIGASRKTFWKRKKINNGSDRSIEKNTQVLKKVNKTQAKSEDQSRLVQEHINEEKDERLYCENNDKPAESESEKPTLLSTGQCNRAEEGSNSTTGFLKTALQGPTVLMVKNNRITIPANYSAKFMGFKMVDGKQHIVIKLLPTSKQNLYLPGSQSGATRHSTANLQPQTLDTTAFLTGVTTELNDTIYMKASTPFSCSSPIRSGKVTSEKEVALLSQTSNMLPTMDDEKSVSSLPTTSELITASVNLTTKVETRDNVDLWGSHIAQCHPEVSGTAIKSPDKVTCTVKPNPYSSGDMHNYCINYVNSELPVESSNQGSLPFHNYSKVNNSNKRRRFSGTATCENPQKESSLSKTVVQQPISESVLSLVRKESSNPDSLLASISLLNTKDGTLKTQAEMEEQCVLEKGQNIDGQNLYTNENQNLESLTEKPKWDDISSDESPMMPRITSVFSLQSQQASEFLPPEVNQLLQEVLKAKPDVKQDSSNTPSKDLRLHCDQSFQKHEREDKIVECSKDLKGQGLFPVPSCSMGINGPTNDPNLKCGGKEKQMLSMSQDVRDSEKTPRISGFGTLLKTQSDAIITQQLVKDKLRATTQNLGSLYMQSPLLNSEPKKALFVQTPRGFFVPLHIANKPGLHASGKPLPLVNTQGVPASLLLNKKPGMILTFNNGKLEGVSAVKTESAQACGTTTKEPCRPPILKVEPSSNCLTPALCSSIGSCLSMKSSSENTLSLKGPYIIKTPASSSVKAVPTPNTVSEHQGTKLNISDSVKQQNKIFPKPPLYTLLPDGKQAVFLKCVMPNKTELLKPKLVQNSTYYKNIQPKKPEGTPQKILLKIFNPVLNVTAANNLSVSNSASSASSSQKDNVPSHPATGGEQKEPESSRDALPFLLDDMMPANEIVITSTATCPESSEEPVCITDHSEARVLRRKTNCTIERCVNKKKTLKKNFSRIKTHLRSKDSETAFVSRNRNCKRKCRDSYQEPPRKKALHRKCKEKAKPEDISESFGYSKPRLSKDSVRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADAPEVVNVMKTIAKFNGRVLKVSLSKRTINALLKPVCCNSSKTICDDFPKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENVLKAKFNCWFCGRVFDNQDTWAGHGQRHLMEATRDWNMLE", "length": 1491 }, "evidence": [ { "id": "E1BXZ2", "url": "https://omabrowser.org/oma/group/E1BXZ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q499R0-1", "protein_name": "Zinc finger protein 518A", "gene_name": "Znf518a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFEQTQLFCDEKQTILKKIDTRNEIPDTIKSIPIPKISEAGFHYEPKNVNICLPKINIPNEILMKHEVEKYRKLFQSKPQTARKSVSVRTVSCAKGCAQRCESERAEDEAGKMCAKILNFTCSKCQDRTQYSPNDLQKHFEMWHHGELPSFPCEMCSFSASDFQIFKQHRKTHRNTFVKCDICNSERSYTLLDLTKHFTSKHCVNGNFQCEECRFFTQDVGTFVQHIHRHKEVHYKCGKCHHLCFTKGELQKHLRVHSGTLPFTCHYCSYGAIHKDQLVRHVITLHKEHLYAKEKLERDQYDKRVAKTTTGLKLILKRYKIGPTKTFWKRKTIASGNDESIGKNAQAFNIVSKTQTKSEDQSQEQLNEEKGGRQHCEDGDKPIESGSEKATVLSTGQCNKADEGASAPSSVLSAVQGPTVLLVRNNKITIPANYSAKFMGFKMVDGRQHIVIKLLPANKQILPSPALQPNTEKESTANLPPQAMDNTGFATGLTAMNDTDFVKAAPLSCSSPELPRKVISEKETAFISEKNNMLQMVDDSKSVTSLPTPSESVTSVRLTTKVEARDNVDLWENPSTQSHPDLIGTSINSPDKVNLTIRPNAYSCGDMHNYCINYVNSELPAESSNCFEFSNQGSLPFHNYSKVNNKRRRFSRGAVCENLQRESSNKTVTQQSTSDSDTTSPLRKESSNSDSLLASISPLSGTLKIKTEIEEPCDLEETQNFNEQSLFTNENQNLLNMTEEPKWDDIPCAGSPMMPRITSVFSLQSEQASEFLPPEVNQLLQDTLKPRSDIKEDSNNIPSKNLPLDCDQTLKKSKEEVIKSSKDFQMQDIISVPSASVGVNVPANDLNLKCNGQEKQALSVLQDVRDPGVTTKIPSIITLLKTQSDAIITQQLVKDKLRTTTQHSGPVYVQNPLLTSEQKNPVFVQTPKGFIIPLHVANKPGLHVFSGRPVPLVNTQSVPAALLVNKKPGVVLTVNNGKPEGVPTVKTENVHSYGTVTKEPCRTPFLKAEHNRYCLTPGLCSSIGSCVNMKTCSENTLPLKGSYIIKTSVSSSVKAVPFANVLPEQQGPNVNVLDAVKQQNESLPKASLYTLMPDGKQAVFFKCMMPNNTKLLKPRLVQNSTYQRIQPKRPAGAPQKILLKIFNPVLSMSAVNNLSVGNSASSFQKEIVPSKPTVHGEQKVPQSSRDALPVSVQDLMPANEAVLSSTAACPGSSEEPVHISERSETRVSRSKANCTIERNFNKRKTCKNKFAKIKTRISQDSETAFVSRNRSCKRKYIDNYQEPPRKKSATHRKCKERANAEDVQETFGFSRPRLPKDSGRTLRLFPFNSEQLVKCPRRNQPVVVLNHPDADAPEVERVMKTITKFNGRVLKVSLSKATINALLKPVSITSETTYSDFSKRHKMLKPVNSVKERFVLKLTLKKTSKNNYQIVKTTSEDVLKSKFNCWFCGRVFDNQDVWAGHGQRHLVEATKDWNMLE", "length": 1478 }, "evidence": [ { "id": "E1BXZ2", "url": "https://omabrowser.org/oma/group/E1BXZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AHZ1-1", "protein_name": "Zinc finger protein 518A", "gene_name": "ZNF518A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSEQKQLFCDEKQTTLKKDYDVKNEIVDRSAPKPKISGSIHYALKNVKIDLPKINIPNEVLLKHEVDKYRKLFQSKQQTARKSISIKTVSCVEECTLLHKSERAEEEGVKMSAKILNFSCLKCRDNTRYSPNDLQKHFQMWHHGELPSYPCEMCNFSANDFQVFKQHRRTHRSTLVKCDICNNESVYTLLNLTKHFTSTHCVNGNFQCEKCKFSTQDVGTFVQHIHRHNEIHYKCGKCHHVCFTKGELQKHLHIHSGTFPFTCQYCSYGATRREHLVRHVITLHKEHLYAKEKLEKDKYEKRMAKTSAGLKLILKRYKIGASRKTFWKRKKINSGSDRSIEKNTQVLKKMNKTQTKSEDQSHVVQEHLSEEKDERLHCENNDKAPESESEKPTPLSTGQGNRAEEGPNASSGFMKTAVLGPTLKNVMMKNNKLAVSPNYNATFMGFKMMDGKQHIVLKLVPIKQNVCSPGSQSGAAKDGTANLQPQTLDTNGFLTGVTTELNDTVYMKAATPFSCSSSILSGKASSEKEMTLISQRNNMLQTMDYEKSVSSLSATSELVTASVNLTTKFETRDNVDFWGNHLTQSHPEVLGTTIKSPDKVNCVAKPNAYNSGDMHNYCINYGNCELPVESSNQGSLPFHNYSKVNNSNKRRRFSGTAVYENPQRESSSSKTVVQQPISESFLSLVRQESSKPDSLLASISLLNDKDGTLKAKSEIEEQYVLEKGQNIDGQNLYSNENQNLECATEKSKWEDFSNVDSPMMPRITSVFSLQSQQASEFLPPEVNQLLQDVLKIKPDVKQDSSNTPNKGLPLHCDQSFQKHEREGKIVESSKDFKVQGIFPVPPGSVGINVPTNDLNLKFGKEKQVSSIPQDVRDSEKMPRISGFGTLLKTQSDAIITQQLVKDKLRATTQNLGSFYMQSPLLNSEQKKTIIVQTSKGFLIPLNITNKPGLPVIPGNALPLVNSQGIPASLFVNKKPGMVLTLNNGKLEGVSAVKTEGAPARGTVTKEPCKTPILKVEPNNNCLTPGLCSSIGSCLSMKSSSENTLPLKGPYILKPTSSVKAVLIPNMLSEQQSTKLNISDSVKQQNEIFPKPPLYTFLPDGKQAVFLKCVMPNKTELLKPKLVQNSTYQNIQPKKPEGTPQRILLKIFNPVLNVTAANNLSVSNSASSLQKDNVPSNQIIGGEQKEPESRDALPFLLDDLMPANEIVITSTATCPESSEEPICVSDCSESRVLRCKTNCRIERNFNRKKTSKKIFSKTKTHGSKDSETAFVSRNRNCKRKCRDSYQEPPRRKATLHRKCKEKAKPEDVRETFGFSRPRLSKDSIRTLRLFPFSSKQLVKCPRRNQPVVVLNHPDADAPEVVSVMKTIAKFNGHVLKVSLSKRTINALLKPVCYNPPKTTYDDFSKRHKTFKPVSSVKERFVLKLTLKKTSKNNYQIVKTTSENILKAKFNCWFCGRVFDNQDTWAGHGQRHLMEATRDWNMLE", 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{ "database": "UniProtKB", "id": "E1BXZ2", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1BXZ2", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1084, "end_pos": 1086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1208, "end_pos": 1210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1249, "end_pos": 1251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" 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"structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BXZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXZ2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 1506, "end_pos": 1533, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 1084, "end_pos": 1086 }, { "start_pos": 1204, "end_pos": 1206 }, { "start_pos": 1208, "end_pos": 1210 }, { "start_pos": 1249, "end_pos": 1251 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 784, "end_pos": 786 }, { "start_pos": 827, "end_pos": 829 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BY06-1", "uniprot_ac": "E1BY06", "uniprot_id": "E1BY06_CHICK", "mass": { "chemical_mass": 46552.0, "monoisotopic_mass": 46552.0 }, "refseq": { "ac": "XP_419397", "name": "BRO1 domain-containing protein BROX", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419397" }, "gene_names": [ { "name": "BROX", "type": "recommended", "evidence": [ { "id": "E1BY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY06" } ] }, { "name": "BROX", "type": "synonym", "evidence": [ { "id": "XP_419397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419397" } ] } ], "protein_names": [ { "name": "BRO1 domain-containing protein BROX", "type": "recommended", "evidence": [ { "id": "E1BY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY06/entry#names_and_taxonomy" } ] }, { "name": "BRO1 domain- and CAAX motif-containing protein", "type": "synonym", "evidence": [ { "id": "E1BY06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY06/entry#names_and_taxonomy" } ] }, { "name": "BRO1 domain-containing protein BROX", "type": "synonym", "evidence": [ { "id": "XP_419397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419397" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419397" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BY06", "url": "https://www.uniprot.org/uniprotkb/E1BY06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BROX", "url": "https://www.uniprot.org/uniprotkb/E1BY06", "locus": { "chromosome": "3", "start_pos": 17671059, "end_pos": 17693380, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016796", "url": "https://www.ensembl.org/id/ENSGALG00010016796" } ] } } ], "crossref": [ { "id": "E1BY06", "url": "https://alphafold.ebi.ac.uk/entry/E1BY06", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009413", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009413", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09243", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09243", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421334", "url": "https://www.ncbi.nlm.nih.gov/gene/421334", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421334", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421334", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YNYCGEN", "url": "https://omabrowser.org/oma/group/YNYCGEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BY06", "url": "https://www.orthodb.org/?gene=E1BY06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23032:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23032:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419397", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BY06", "url": "https://www.uniprot.org/uniprotkb/E1BY06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BY06-1", "url": "https://www.uniprot.org/uniprotkb/E1BY06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHWFHRNPLKATAPVQFNYYGVATTPASSKICNDLRLSRTRLLELFTDLSCNPEMMKNATDLYFSLLQGFILSLDDSSQECKLRYIQNFKWTDTLQGHVPCAQQDAVFELVSMGFNVALWYTKYASRLAGKEDITEDEAKDVHRSLKIAAGIFKHLKECHIPKLITPVEKGRDLEARLIDSYIIQCQAEAQEVTIARAIELKHNPGLIAALAYETANFYQKADQTLSSLDPTYAGKWRKYLNLKSCFYMAYAYCYHGQTLLASDKCGEAIRSLQESEKFFAKAEALCKEYGETKGPGTTAKPSGHLFFRKLGSLIKNTLEKCQRENGFIYFQKVPAEAPQLELKANYGLVEPVPFEFPALNAHWTPETLAAFDLTKRPKDDTAKPKPDEEVKPLKEPDIKPQKDSGCRIS", "length": 411, "header": "tr|E1BY06-1|E1BY06_CHICK Isoform 1 of BRO1 domain-containing protein BROX OS=Gallus gallus OX=9031 GN=BROX PE=1 SV=3 CANONICAL=E1BY06-1" }, "isoforms": [ { "isoform_ac": "E1BY06-1", "url": "https://www.uniprot.org/uniprotkb/E1BY06/entry#E1BY06-1", "sequence": { "sequence": "MTHWFHRNPLKATAPVQFNYYGVATTPASSKICNDLRLSRTRLLELFTDLSCNPEMMKNATDLYFSLLQGFILSLDDSSQECKLRYIQNFKWTDTLQGHVPCAQQDAVFELVSMGFNVALWYTKYASRLAGKEDITEDEAKDVHRSLKIAAGIFKHLKECHIPKLITPVEKGRDLEARLIDSYIIQCQAEAQEVTIARAIELKHNPGLIAALAYETANFYQKADQTLSSLDPTYAGKWRKYLNLKSCFYMAYAYCYHGQTLLASDKCGEAIRSLQESEKFFAKAEALCKEYGETKGPGTTAKPSGHLFFRKLGSLIKNTLEKCQRENGFIYFQKVPAEAPQLELKANYGLVEPVPFEFPALNAHWTPETLAAFDLTKRPKDDTAKPKPDEEVKPLKEPDIKPQKDSGCRIS", "length": 411, "header": "tr|E1BY06-1|E1BY06_CHICK Isoform 1 of BRO1 domain-containing protein BROX OS=Gallus gallus OX=9031 GN=BROX PE=1 SV=3 CANONICAL=E1BY06-1" }, "locus": { "chromosome": "3", "start_pos": 17691886, "end_pos": 17680936, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040525.1", "url": "https://www.ensembl.org/id/ENSGALT00010040525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023525.1", "url": "https://www.ensembl.org/id/ENSGALP00010023525.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421334", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421334", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1THH2-1", "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "BROX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTHWFHRNPLKATAPVSFNYYGVITGPAASKICSDLRSSRARLLELFTDLSCNPEMMKSAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHIAKLITPAEKGRDLEARLLEAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQEAEKFYAKAEALCKEYGETKGPGPTVKPSGHLFFRKLGTLVKNTLEKCQRENGFIYFQKVPTEAPQLELKANYGLVEPVPFEFPPLSSHWTPEAMAAFDLTQRPKDDRGKPKPEEVVKPVKEPDIKPQKDTGCSVS", "length": 411 }, "evidence": [ { "id": "E1BY06", "url": "https://omabrowser.org/oma/group/E1BY06/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2QPJ1-1", "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "Brox", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTHWFHRNPLKATAPVSFNYYGMITGPAASKICNDLRSSRTRLLELFTDLSCNPETMKNAADLYFSLLQGFINSLGDSTQESKLRYVQSFKWTDTLQGHVPSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHIPKLLTPAEKGQDLEARLIDAYVIQCQAEAQEVTIARAIELQHAPGLIAALAYETASFYQRADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQEAEKLYTEAEALCKEYGETKGPGPTAKPSGHLFFRKLGSLVKNTLDKCQRENGFIYFQKIPTEAPQLELKANYGLVEPVPFEFPPMSAHWTPEALAAFDLTKRPKDDSVKPKPEEEVKPVKEPDIKPQKDTGCSVS", "length": 411 }, "evidence": [ { "id": "E1BY06", "url": "https://omabrowser.org/oma/group/E1BY06/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9T5V2-1", "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "BROX", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTHWFHRNPLKATAPVSFNYYGVVTGPAASKICSDLRSSRARLLELFTDLSCNPEMMKNAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSITEDEAKEVHRSLKIAAGIFKHLKESHIPKLITPAEKGRDLEARLIEAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYETANFYQKADHALSSLEPAYSAKWRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQEAEKFYAKAEALCKEYGETKGPGPTVKPSGHLFFRKLGNLVKNTLEKCQRENGFIYFQKVPTEAPQLELKANYGLVEPVPFEFPPPSAHWTPETLAAFDLTKRPKDDSAKPKPEEVVKPVKEPDIKPQKDTGCYIS", "length": 379 }, "evidence": [ { "id": "E1BY06", "url": "https://omabrowser.org/oma/group/E1BY06/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A3KQV2-1", "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "brox", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHWFHRNPLKATAPVSFNLYGVASSPAANKICNDLRTARARLLDMFTDATCSPDTLKKSSDEYFALLQGFILPLDGTTQENKLRFIQNFKWTDTLQGNIASAQQDAVFELVSMAFNVALWYTKFASRLAGKENITEEEAKDVHKSLKIAAGIFKTLKETHIPRLITPAEKGRDLEPRVIDTYIVQSQAEAQEVTIARAIELKHNASLIAALAFETANFYQKADHTLNTLDPECSSKWKKYLQLKQHFYMAYAHCYHGQTLLAGDKCGEAIRSLQEAEKCYSRAEVLCKEYRQMKGPGSTAKPSEQLFFKKLGAVIKNTLEKCQRENGFIYFHKVPAEAPALELKASYGLAEPTAFELPPLSAQCTPEVYATFDLTRGHKDDKAKAKPEEEIKPVKEPDLKPQKDTGCVVC", "length": 411 }, "evidence": [ { "id": "E1BY06", "url": "https://omabrowser.org/oma/group/E1BY06/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4V8K5-1", "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "Brox", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTHWFHRNPLKATAPVSFNYYGMITGPPASKICNDLRSARTRLLELFTDLSCNPETMKNAADLYFSLLQGFINSVGDSTQESKLRYIQNFKWTDTLQGHVPSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHIPKLLTPAEKGRDLEARLIDAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYETASFYQKADHTLSSLEPAHSAKWRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQEAEKLYAEAEALCKEYGETKGPGPTAKPSGHLFFRKLGSLVKNTLDKCQRENGFIYFQKIPTEAPQLELKANYGLVEPVPFEFPPMSALWTPEALAAFDLTKRPKDDSIKPKPEEEVKPVKEPDIKPQKDTGCSVS", "length": 411 }, "evidence": [ { "id": "E1BY06", "url": "https://omabrowser.org/oma/group/E1BY06/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VW32-1", "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "BROX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTHWFHRNPLKATAPVSFNYYGVVTGPSASKICNDLRSSRARLLELFTDLSCNPEMMKNAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHLPKLITPAEKGRDLESRLIEAYVIQCQAEAQEVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCYHGETLLASDKCGEAIRSLQEAEKLYAKAEALCKEYGETKGPGPTVKPSGHLFFRKLGNLVKNTLEKCQRENGFIYFQKIPTEAPQLELKANYGLVEPIPFEFPPTSVQWTPETLAAFDLTKRPKDDSTKPKPEEEVKPVKEPDIKPQKDTGCYIS", "length": 411 }, "evidence": [ { "id": "E1BY06", "url": "https://omabrowser.org/oma/group/E1BY06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K2Q7-1", "protein_name": "BRO1 domain-containing protein BROX", "gene_name": "Brox", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHWFHRNPLKATAPVSFNYYGMITGPPASKICNDLRSARTRLLELFTDLSCNPETMKNAADLYFSLLQGFINSVGDSTQESKLRYIQNFKWTDTLQGHVPSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHIPKLLTPAEKGRDLEARLIDAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYDTASFYQKADHTLSSLEPAHSAKWRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQEAEKLYAEAEALCKEYGETKGPGPTAKPSGHLFFRKLGSLVKNTLDKCQRENGFIYFQKIPTEAPQLELKANYGLVEPVPFEFPPMSAHWTPEALAAFDLTKRPKDDSVKPKPEEDVKPVKEPDIRPQKDTGCSVS", "length": 411 }, "evidence": [ { "id": "E1BY06", "url": "https://omabrowser.org/oma/group/E1BY06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "E1BY06", "url": "https://www.uniprot.org/uniprotkb/E1BY06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitotic nuclear membrane reassembly", "id": "GO:0007084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007084", "evidence": [ { "database": "UniProtKB", "id": "E1BY06", "url": "https://www.uniprot.org/uniprotkb/E1BY06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BY06-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 411, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BY06-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BY06" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BY36-1", "uniprot_ac": "E1BY36", "uniprot_id": "E1BY36_CHICK", "mass": { "chemical_mass": 70217.0, "monoisotopic_mass": 70217.0 }, "refseq": { "ac": "XP_004938504", "name": "probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938504" }, "gene_names": [ { "name": "ASMTL", "type": "recommended", "evidence": [ { "id": "E1BY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY36" } ] }, { "name": "ASMTL", "type": "synonym", "evidence": [ { "id": "XP_004938504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938504" } ] } ], "protein_names": [ { "name": "Acetylserotonin O-methyltransferase like", "type": "synonym", "evidence": [ { "id": "E1BY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY36/entry#names_and_taxonomy" } ] }, { "name": "probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938504" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938504", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938504" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BY36", "url": "https://www.uniprot.org/uniprotkb/E1BY36" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASMTL", "url": "https://www.uniprot.org/uniprotkb/E1BY36", "locus": { "chromosome": "1", "start_pos": 129258622, "end_pos": 129231562, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001807", "url": "https://www.ensembl.org/id/ENSGALG00010001807" } ] } } ], "crossref": [ { "id": "E1BY36", "url": "https://alphafold.ebi.ac.uk/entry/E1BY36", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016689", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016689", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00555", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00555", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769097", "url": "https://www.ncbi.nlm.nih.gov/gene/769097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769097", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VLCHEKD", "url": "https://omabrowser.org/oma/group/VLCHEKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X3M0", "url": "https://www.orthodb.org/?gene=A0A8V0X3M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XA57", "url": "https://www.orthodb.org/?gene=A0A8V0XA57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BY36", "url": "https://www.orthodb.org/?gene=E1BY36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43213:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43213:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00891", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00891", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004938504", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938504", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X3M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XA57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XA57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XA57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BY36", "url": "https://www.uniprot.org/uniprotkb/E1BY36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BY36-1", "url": "https://www.uniprot.org/uniprotkb/E1BY36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLSPVLGKLVSKRVVLASASPRRQEILTNVGLRFEVVPSWFKETLEKSSFAAPYEYAIETAKQKALEVANRMHVKHLRTPDIVIGADTIVTVDEQILEKPVDKQDAYRMLSRLSGKEHSVFTGVVIIHCSSKDNQLETEITDFYEETKVKFSDLSEELLWEYIHSGEPMDKAGGYGIQALGGMLVEYVHGDFLNVVGFPLNHFCKKLAELYCPPLKHTIQHIKHDSIPSVDTFESLSDGESESSSFKEHKGAIKLDSPSGVICNSENSSGVRTGSVVPLENQNGVSDSAAKVPSKILDLMDGFRASKALFVASKLKMFDHLKKKSPLKAVDIANEAGTSVCGTERLLDACTALGLLEKTPQGYSNTDSANTYLASDGEYSLHGYIIHSNDHLWPLFTHLESAVKEGSRQNHRAFGKKTEDLFNDYYQSQEVKQRFMAAMHSIARLTARDVATAFDLSEFKTACDLGGCTGALAHELIQIYPNMKVTVFDLPEVIANTSCFQPSEQRVASVTFVSGNFFTDDLPEADLYILSRVLHDWPDEKIHILLKKISAVCRPGSALLVAETVLDEQKIHPPRVVLQSLSMTEGKQRSGSEYKQLLEKYGFTNTQIKITGNLLDVVLCFKKSVILACTEIA", "length": 634, "header": "tr|E1BY36-1|E1BY36_CHICK Isoform 1 of Acetylserotonin O-methyltransferase like OS=Gallus gallus OX=9031 GN=ASMTL PE=1 SV=3 CANONICAL=E1BY36-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X3M0-1", "url": "https://www.uniprot.org/uniprotkb/E1BY36/entry#A0A8V0X3M0-1", "sequence": { "sequence": "MVLSPVLGKLVSKRVVLASASPRRQEILTNVGLRFEVVPSWFKETLEKSSFAAPYEYAIETAKQKALEVANRMHVKHLRTPDIVIGADTIVTVDEQILEKPVDKQDAYRMLSRLSGKEHSVFTGVVIIHCSSKDNQLETEITDFYEETKVKFSDLSEELLWEYIHSGEPMDKAGGYGIQALGGMLVEYVHGDFLNVVGFPLNHFCKKLAELYCPPLKHTIQHIKHDSIPSVDTFESLSDGESESSSFKEHKGAIKLDSPSGVICNSENSSGVRTGSVVPLENQNGVSDSAAKVPSKILDLMDGFRASKALFVASKLKMFDHLKKKSPLKAVDIANEAGTSVCGTERLLDACTALGLLEKTPQGYSNTDSANTYLASDGEYSLHGYIIHSNDHLWPLFTHLESAVKEGSRQNHRAFGKKTEDLFNDYYQSQEVKQRFMAAMHSIARLTARDVATAFDLSEFKTACDLGGCTGALAHELIQIYPNMKVTVFDLPEVIANTSCFQPSEQRVASVTFVSGNFFTDDLPEADLYILSRVLHDWPDEKIHILLKKISAVCRPGVLPRLVVLSRLWDFAG", "length": 573, "header": "tr|A0A8V0X3M0-1|A0A8V0X3M0_CHICK Computationally mapped isoform of Acetylserotonin O-methyltransferase like OS=Gallus gallus OX=9031 GN=ASMTL PE=1 SV=1 CANONICAL=E1BY36-1" }, "locus": { "chromosome": "1", "start_pos": 129257747, "end_pos": 129231604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004115.1", "url": "https://www.ensembl.org/id/ENSGALT00010004115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002412.1", "url": "https://www.ensembl.org/id/ENSGALP00010002412.1" } ] } }, { "isoform_ac": "A0A8V0XA57-1", "url": "https://www.uniprot.org/uniprotkb/E1BY36/entry#A0A8V0XA57-1", "sequence": { "sequence": "MVLSPVLGKLVSKRVVLASASPRRQEILTNVGLRFEVVPSWFKETLEKSSFAAPYEYAIETAKQKALEVANRMHVKHLRTPDIVIGADTIVTVDEQILEKPVDKQDAYRMLSRLSGKEHSVFTGVVIIHCSSKDNQLETEITDFYEETKVKFSDLSEELLWEYIHSGEPMDKAGGYGIQALGGMLVEYVHGDFLNVVGFPLNHFCKKLAELYCPPLKHTIQHIKHDSIPSVDTFESLSDGESESSSFKEHKGAIKLDSPSGVICNSENSSGVRTGSVVPLENQNGVSDSAAKVPSKILDLMDGFRASKALFVASKLKMFDHLKKKSPLKAVDIANEAGTSVCGTERLLDACTALGLLEKTPQGYSNTDSANTYLASDGEYSLHGYIIHSNDHLWPLFTHLESAVKEGSRQNHRAFGKKTEDLFNDYYQSQEVKQRFMAAMHSIARLTARDVATAFDLSEFKTACDLGGCTGALAHELIQIYPNMKVTVFDLPEVIANTSCFQPSEQRVASVTFVSGNFFTDDLPEADLYILSRVLHDWPDEKIHILLKKISAVCRPGCGILLAEMLLDDEKKNGRTALLQSLNMLVQTEGKERSGSDYRGLLEQHGFSKVKIKLTGNLLDAVLCVKI", "length": 627, "header": "tr|A0A8V0XA57-1|A0A8V0XA57_CHICK Computationally mapped isoform of Acetylserotonin O-methyltransferase like OS=Gallus gallus OX=9031 GN=ASMTL PE=1 SV=1 CANONICAL=E1BY36-1" }, "locus": { "chromosome": "1", "start_pos": 129257940, "end_pos": 129231604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004117.1", "url": "https://www.ensembl.org/id/ENSGALT00010004117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002414.1", "url": "https://www.ensembl.org/id/ENSGALP00010002414.1" } ] } }, { "isoform_ac": "E1BY36-1", "url": "https://www.uniprot.org/uniprotkb/E1BY36/entry#E1BY36-1", "sequence": { "sequence": "MVLSPVLGKLVSKRVVLASASPRRQEILTNVGLRFEVVPSWFKETLEKSSFAAPYEYAIETAKQKALEVANRMHVKHLRTPDIVIGADTIVTVDEQILEKPVDKQDAYRMLSRLSGKEHSVFTGVVIIHCSSKDNQLETEITDFYEETKVKFSDLSEELLWEYIHSGEPMDKAGGYGIQALGGMLVEYVHGDFLNVVGFPLNHFCKKLAELYCPPLKHTIQHIKHDSIPSVDTFESLSDGESESSSFKEHKGAIKLDSPSGVICNSENSSGVRTGSVVPLENQNGVSDSAAKVPSKILDLMDGFRASKALFVASKLKMFDHLKKKSPLKAVDIANEAGTSVCGTERLLDACTALGLLEKTPQGYSNTDSANTYLASDGEYSLHGYIIHSNDHLWPLFTHLESAVKEGSRQNHRAFGKKTEDLFNDYYQSQEVKQRFMAAMHSIARLTARDVATAFDLSEFKTACDLGGCTGALAHELIQIYPNMKVTVFDLPEVIANTSCFQPSEQRVASVTFVSGNFFTDDLPEADLYILSRVLHDWPDEKIHILLKKISAVCRPGSALLVAETVLDEQKIHPPRVVLQSLSMTEGKQRSGSEYKQLLEKYGFTNTQIKITGNLLDVVLCFKKSVILACTEIA", "length": 634, "header": "tr|E1BY36-1|E1BY36_CHICK Isoform 1 of Acetylserotonin O-methyltransferase like OS=Gallus gallus OX=9031 GN=ASMTL PE=1 SV=3 CANONICAL=E1BY36-1" }, "locus": { "chromosome": "1", "start_pos": 129252896, "end_pos": 129231604, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004113.1", "url": "https://www.ensembl.org/id/ENSGALT00010004113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002410.1", "url": "https://www.ensembl.org/id/ENSGALP00010002410.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769097", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3MY50-1", "protein_name": "Acetylserotonin O-methyltransferase like", "gene_name": "ASMTL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLLCPVIGKLQHKRVVLASSSPRRREILSNAGLRFEVVPSRFKEKLHKASFATPQAYAVETAKQKALEVADRMYQKDLRAPDVVIGADTIVAVGGLILEKPVDKQDAYRMLSRLSGKEHSVFTGVAIVHCYTKDGQLDTEVSEFYEETTVKFSELSEEMLWEYIDSGEPMDKAGGYGIQALGGMLVEYVRGDFLNVVGFPLNRFCKELAHLYHGPRAHGAPRQVRHDSIPAVDTFEDLSDAEGGGSDPARAKEGLEPCGVQPQAPRPREADLNGVTDSQPPLPVGLLELMDGFKASKALLTACKLQVFDVLKERGPLAAADVAREIDASVGGTARLLDVCAALGLLDKSDRGYSNTEMASLHLASDGEQSLHGLAAYHDGPVWGAFTHLGRAVREGAAWTPEPLPQAPHKWSTEATLQFMRASHGLSKLTAQHVATAFDLSPFTSACHLGGCTGALAHKLVQEYPHLQVTIFALPEVIKLAGDFETNARPSERVHFVPGDLSSDSLPPADLYIVCSLLHDWPDDRLHGLLSRVSGCCKPGAGLLLAELAPAEEEDASGAARRPPGLRALGVGRPPRNPGQYQRLLQRLGFQDVQAACAAGLLHVVLGTRAPP", "length": 612 }, "evidence": [ { "id": "E1BY36", "url": "https://omabrowser.org/oma/group/E1BY36/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95671-1", "protein_name": "Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein", "gene_name": "ASMTL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLCPVIGKLLHKRVVLASASPRRQEILSNAGLRFEVVPSKFKEKLDKASFATPYGYAMETAKQKALEVANRLYQKDLRAPDVVIGADTIVTVGGLILEKPVDKQDAYRMLSRLSGREHSVFTGVAIVHCSSKDHQLDTRVSEFYEETKVKFSELSEELLWEYVHSGEPMDKAGGYGIQALGGMLVESVHGDFLNVVGFPLNHFCKQLVKLYYPPRPEDLRRSVKHDSIPAADTFEDLSDVEGGGSEPTQRDAGSRDEKAEAGEAGQATAEAECHRTRETLPPFPTRLLELIEGFMLSKGLLTACKLKVFDLLKDEAPQKAADIASKVDASACGMERLLDICAAMGLLEKTEQGYSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQHHRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGCTGALARELAREYPRMQVTVFDLPDIIELAAHFQPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLLLVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDAILATKVAP", "length": 621 }, "evidence": [ { "id": "E1BY36", "url": "https://omabrowser.org/oma/group/E1BY36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BY36", "url": "https://www.uniprot.org/uniprotkb/E1BY36" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "E1BY36", "url": "https://www.uniprot.org/uniprotkb/E1BY36" } ], "pmid": "" }, { "name": "O-methyltransferase activity", "id": "GO:0008171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008171", "evidence": [ { "database": "UniProtKB", "id": "E1BY36", "url": "https://www.uniprot.org/uniprotkb/E1BY36" } ], "pmid": "" }, { "name": "nucleoside triphosphate diphosphatase activity", "id": "GO:0047429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047429", "evidence": [ { "database": "UniProtKB", "id": "E1BY36", "url": "https://www.uniprot.org/uniprotkb/E1BY36" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "E1BY36", "url": "https://www.uniprot.org/uniprotkb/E1BY36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BY36-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 634, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BY36-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BY36" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY36" }, { "id": "PF00891", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00891" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "O-methyltransferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 397, "end_pos": 604, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY36" }, { "id": "PF08100", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08100" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "O-methyltransferase dimerisation", "eco_id": "ECO_0000259", "start_pos": 298, "end_pos": 376, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 497, "end_pos": 499 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BY86-1", "uniprot_ac": "E1BY86", "uniprot_id": "E1BY86_CHICK", "mass": { "chemical_mass": 28934.0, "monoisotopic_mass": 28934.0 }, "refseq": { "ac": "XP_420681", "name": "protein FRG1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420681" }, "gene_names": [ { "name": "FRG1BP", "type": "recommended", "evidence": [ { "id": "E1BY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ] }, { "name": "FRG1BP", "type": "synonym", "evidence": [ { "id": "XP_420681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420681" } ] } ], "protein_names": [ { "name": "Protein FRG1", "type": "recommended", "evidence": [ { "id": "E1BY86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY86/entry#names_and_taxonomy" } ] }, { "name": "protein FRG1", "type": "synonym", "evidence": [ { "id": "XP_420681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420681" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420681" } ] }, { "annotation": "Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B.", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86#function" }, { "database": "UniProtKB", "id": "ARBA00059473", "url": "https://www.uniprot.org/uniprotkb/ARBA00059473#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FRG1BP", "url": "https://www.uniprot.org/uniprotkb/E1BY86", "locus": {} } ], "crossref": [ { "id": "E1BY86", "url": "https://alphafold.ebi.ac.uk/entry/E1BY86", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013590", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013590", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23338", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23338", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422726", "url": "https://www.ncbi.nlm.nih.gov/gene/422726", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422726", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422726", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IEQWEPI", "url": "https://omabrowser.org/oma/group/IEQWEPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BY86", "url": "https://www.orthodb.org/?gene=E1BY86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12928", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12928", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12928:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12928:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420681", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BY86-1", "url": "https://www.uniprot.org/uniprotkb/E1BY86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEYSCVKSTKLVLKGAKEKSKKKHKNKKRKRDEDAEEQLDIVGNWWAVSNFGEITGTIAIEMDKGAYIHALDNGLFTLGAPHRDDEGPSPPEQFTAVKLSDTRIALKSGYGKYLGINSDGLVVGRSDAIGSREQWEPVFQDKKMALLAANSRFIRCNEDGDIEAKSKTAGEEEMIKIRTCAERETKKKDDVPQEDKGNVKQCEINYVKKFQSFQDKKLKVSKEDTKALRKARKEGTFHEALLDRRAKVKADRYCK", "length": 256, "header": "tr|E1BY86-1|E1BY86_CHICK Isoform 1 of Protein FRG1 OS=Gallus gallus OX=9031 GN=FRG1BP PE=3 SV=3 CANONICAL=E1BY86-1" }, "isoforms": [ { "isoform_ac": "E1BY86-1", "url": "https://www.uniprot.org/uniprotkb/E1BY86/entry#E1BY86-1", "sequence": { "sequence": "MAEYSCVKSTKLVLKGAKEKSKKKHKNKKRKRDEDAEEQLDIVGNWWAVSNFGEITGTIAIEMDKGAYIHALDNGLFTLGAPHRDDEGPSPPEQFTAVKLSDTRIALKSGYGKYLGINSDGLVVGRSDAIGSREQWEPVFQDKKMALLAANSRFIRCNEDGDIEAKSKTAGEEEMIKIRTCAERETKKKDDVPQEDKGNVKQCEINYVKKFQSFQDKKLKVSKEDTKALRKARKEGTFHEALLDRRAKVKADRYCK", "length": 256, "header": "tr|E1BY86-1|E1BY86_CHICK Isoform 1 of Protein FRG1 OS=Gallus gallus OX=9031 GN=FRG1BP PE=3 SV=3 CANONICAL=E1BY86-1" }, "locus": { "chromosome": "4", "start_pos": 62286935, "end_pos": 62279878, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037753.1", "url": "https://www.ensembl.org/id/ENSGALT00010037753.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021807.1", "url": "https://www.ensembl.org/id/ENSGALP00010021807.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422726", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422726", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IJ78-1", "protein_name": "Protein FRG1", "gene_name": "Frg1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEYSFVKSTKLVLKGSKAKSKKKKSKDKKRKREEDEETQLDIVGIWWTVSNFGEISGTIAIEMDKGAYIHALDNGLFTLGAPHREVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAIGPREQWEPVFQDGKMALLASNSCFIRCNEAGDIEAKNKTAGEEEMIKIRSCAERETKKKDDIPEEDKGNVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK", "length": 258 }, "evidence": [ { "id": "E1BY86", "url": "https://omabrowser.org/oma/group/E1BY86/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6AIP8-1", "protein_name": "Protein FRG1", "gene_name": "Frg1-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEYSYVKSTKLVLKGTKAKSKKKKSKDKKRKREEDEEAQLDIVGIWWTVSNFGEISGTIAIEMDKGAYIHALDNGLFTLGAPHREVDEGSSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAIGPREQWEPVFQDGKMALLASNSCFIRCNEAGDIEAKNKTAGEEEMIKIRSCAEREAKKKDDIAEEDKGSVQQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK", "length": 258 }, "evidence": [ { "id": "E1BY86", "url": "https://omabrowser.org/oma/group/E1BY86/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97376-1", "protein_name": "Protein FRG1", "gene_name": "Frg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEYSYVKSTKLVLKGTKAKSKKKKSKDKKRKREEDEETQLDIVGIWWTVSNFGEISGTIAIEMDKGAYIHALDNGLFTLGAPHREVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAIGPREQWEPVFQDGKMALLASNSCFIRCNEAGDIEAKNKTAGEEEMIKIRSCAERETKKKDDIPEEDKGSVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK", "length": 258 }, "evidence": [ { "id": "E1BY86", "url": "https://omabrowser.org/oma/group/E1BY86/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14331-1", "protein_name": "Protein FRG1", "gene_name": "FRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEYSYVKSTKLVLKGTKTKSKKKKSKDKKRKREEDEETQLDIVGIWWTVTNFGEISGTIAIEMDKGTYIHALDNGLFTLGAPHKEVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVVGRSDAIGPREQWEPVFQNGKMALLASNSCFIRCNEAGDIEAKSKTAGEEEMIKIRSCAERETKKKDDIPEEDKGNVKQCEINYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLDRRAKLKADRYCK", "length": 258 }, "evidence": [ { "id": "E1BY86", "url": "https://omabrowser.org/oma/group/E1BY86/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWA8-1", "protein_name": "Protein FRG1 homolog", "gene_name": "FRG1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDYDHARIKKLVLKGEKLKKSKKRKKEKDEAGSSKKAKVVVDEDAVKHGGWWAAKTAADITGTVSIEFGDRSYLKAMDNGLFTLGAPHNAGDGPDPEEIFTAFPINDRKVAFKSGYGKYLKIEKDGMVTGRSEAVGGMEQWEPVFEEQRMALLSETGHFMSIDPQDDACVALRKKVGQHEICKVRSNASRDVVIDTEPKEEKGDLGEVEKNYVKKFQKFQDKKMRINQNDVKELEQAKAQGSLHETLLDRRSKMKADRYCK", "length": 262 }, "evidence": [ { "id": "E1BY86", "url": "https://omabrowser.org/oma/group/E1BY86/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" }, { "name": "striated muscle dense body", "id": "GO:0055120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055120", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "E1BY86", "url": "https://www.uniprot.org/uniprotkb/E1BY86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BY86-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 256, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BY86-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BY86" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BYA9-1", "uniprot_ac": "E1BYA9", "uniprot_id": "E1BYA9_CHICK", "mass": { "chemical_mass": 42675.0, "monoisotopic_mass": 42675.0 }, "refseq": { "ac": "XP_422661", "name": "integrin-linked kinase-associated serine/threonine phosphatase 2C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422661" }, "gene_names": [ { "name": "ILKAP", "type": "recommended", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] }, { "name": "ILKAP", "type": "synonym", "evidence": [ { "id": "XP_422661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422661" } ] } ], "protein_names": [ { "name": "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "type": "recommended", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9/entry#names_and_taxonomy" } ] }, { "name": "integrin-linked kinase-associated serine/threonine phosphatase 2C", "type": "synonym", "evidence": [ { "id": "XP_422661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422661" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_422661.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422661" } ] }, { "annotation": "Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9#function" }, { "database": "UniProtKB", "id": "ARBA00055237", "url": "https://www.uniprot.org/uniprotkb/ARBA00055237#function" }, { "database": "UniProtKB", "id": "A0A8V1A0Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ILKAP", "url": "https://www.uniprot.org/uniprotkb/E1BYA9", "locus": { "chromosome": "9", "start_pos": 4489463, "end_pos": 4498214, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024937", "url": "https://www.ensembl.org/id/ENSGALG00010024937" } ] } } ], "crossref": [ { "id": "E1BYA9", "url": "https://alphafold.ebi.ac.uk/entry/E1BYA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006253", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424850", "url": "https://www.ncbi.nlm.nih.gov/gene/424850", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424850", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424850", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NFSCFCL", "url": "https://omabrowser.org/oma/group/NFSCFCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A0Z2", "url": "https://www.orthodb.org/?gene=A0A8V1A0Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BYA9", "url": "https://www.orthodb.org/?gene=E1BYA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47992", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47992", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1A0Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BYA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLFGDLPEPGGSAQGKEAQGQLRLFDDLPPAGSADTGKGSSLLFDDLPPASSSDAASSAPEQVSEGSHAKGEKRKSMEEEEKNGREELVEKKVCKGSVGILGLKGYVAERKGEREDMQDAHVILNDITEECQPLPSQVTRVSYFAVFDGHGGVRASKFAAQNLHLNLIKKFPKGEVVSVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVISVPDIKRCQLTHNDRFILIACDGLFKVFTPEEAVNFIVSCLEDKNIQKREGKQEADARYEAACNRLANKAVQRGSADNVTVVVVRIEH", "length": 389, "header": "tr|E1BYA9-1|E1BYA9_CHICK Isoform 1 of Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Gallus gallus OX=9031 GN=ILKAP PE=1 SV=2 CANONICAL=E1BYA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A0Z2-1", "url": "https://www.uniprot.org/uniprotkb/E1BYA9/entry#A0A8V1A0Z2-1", "sequence": { "sequence": "MDLFGDLPEPGGSAQGKGSSLLFDDLPPASSSDAASSAPEQVSEGSHAKGEKRKSMEEEEKNGREELVEKKVCKGSVGILGLKGYVAERKGEREDMQDAHVILNDITEECQPLPSQVTRVSYFAVFDGHGGVRASKFAAQNLHLNLIKKFPKGEVVSVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVISVPDIKRCQLTHNDRFILIACDGLFKVFTPEEAVNFIVSCLEDKNIQKREGKQEADARYEAACNRLANKAVQRGSADNVTVVVVRIEH", "length": 367, "header": "tr|A0A8V1A0Z2-1|A0A8V1A0Z2_CHICK Computationally mapped isoform of Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Gallus gallus OX=9031 GN=ILKAP PE=1 SV=1 CANONICAL=E1BYA9-1" }, "locus": { "chromosome": "9", "start_pos": 4498156, "end_pos": 4489753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060908.1", "url": "https://www.ensembl.org/id/ENSGALT00010060908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037665.1", "url": "https://www.ensembl.org/id/ENSGALP00010037665.1" } ] } }, { "isoform_ac": "E1BYA9-1", "url": "https://www.uniprot.org/uniprotkb/E1BYA9/entry#E1BYA9-1", "sequence": { "sequence": "MDLFGDLPEPGGSAQGKEAQGQLRLFDDLPPAGSADTGKGSSLLFDDLPPASSSDAASSAPEQVSEGSHAKGEKRKSMEEEEKNGREELVEKKVCKGSVGILGLKGYVAERKGEREDMQDAHVILNDITEECQPLPSQVTRVSYFAVFDGHGGVRASKFAAQNLHLNLIKKFPKGEVVSVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVISVPDIKRCQLTHNDRFILIACDGLFKVFTPEEAVNFIVSCLEDKNIQKREGKQEADARYEAACNRLANKAVQRGSADNVTVVVVRIEH", "length": 389, "header": "tr|E1BYA9-1|E1BYA9_CHICK Isoform 1 of Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Gallus gallus OX=9031 GN=ILKAP PE=1 SV=2 CANONICAL=E1BYA9-1" }, "locus": { "chromosome": "9", "start_pos": 4498156, "end_pos": 4489753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060911.1", "url": "https://www.ensembl.org/id/ENSGALT00010060911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010037668.1", "url": "https://www.ensembl.org/id/ENSGALP00010037668.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424850", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7EY20-1", "protein_name": "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "gene_name": "ilkap", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLFDDLPEPTNEPAPVKLQQEERGEKRKRSISSEQTEVQDDKQEEKKVCKEGFAKLTGFVSARRGEREEMQDAHVLLPDLNITCLPSQVSRLAYFAVFDGHGGARASQFAAENLHHTLLSKFPKGDVENLDKLVRKCLLDTFRQTDEDFLKKASSQKPAWKDGSTATCLLAVDDVLYVANLGDSRAVLCRMEQAKDSGKRKCVTLALSKEHNPTIYEERMRIQRAGGTVRDGRVLGVLEVSRSIGDGQYKRCGVISTPDLRRCQLSPNDKFVLLACDGLFKVFSADEAVQFVLGVLENETVELKEGQSEGAGLFEAACQRLASEAVRRGSADNVTVILVSIEFC", "length": 345 }, "evidence": [ { "id": "E1BYA9", "url": "https://omabrowser.org/oma/group/E1BYA9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0IIF0-1", "protein_name": "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "gene_name": "ILKAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLFGDLPEPERSPRPAAGSGGPLLFDDLPPASSGDSGSLDTSLSEEVKNEGKGAKRKASDEEKNGSEELVEKKVCKASSVIFSLKGYVAERKGEREEMQDAHVILNDITAECQPPSALVTRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDGISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNTLYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQRREGKPTVDARYEAACNRLANKAVQRGSADNVTVMVVRIGL", "length": 370 }, "evidence": [ { "id": "E1BYA9", "url": "https://omabrowser.org/oma/group/E1BYA9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R0F6-1", "protein_name": "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "gene_name": "Ilkap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLFGDLPEPERAPRPSAGKEAQGRPVLFEDLPPASSTDSGSGGPLLFDDLPPAASGNSGSLATSGSQVVKTEGKGAKRKAPEEEKNGGEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITQECNPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDIISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDDKIQTREGKPAVDARYEAACNRLANKAVQRGSADNVTVMVVRIGH", "length": 392 }, "evidence": [ { "id": "E1BYA9", "url": "https://omabrowser.org/oma/group/E1BYA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0C8-1", "protein_name": "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "gene_name": "ILKAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLFGDLPEPERSPRPAAGKEAQKGPLLFDDLPPASSTDSGSGGPLLFDDLPPASSGDSGSLATSISQMVKTEGKGAKRKTSEEEKNGSEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVVRIGH", "length": 392 }, "evidence": [ { "id": "E1BYA9", "url": "https://omabrowser.org/oma/group/E1BYA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LMT1-1", "protein_name": "Probable protein phosphatase 2C 8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLEKESDLTAMEKPNNKHAADSFSSEDLVSPVKKAKKSEEVSGGGEAVAAVGNREAEEDKPSFVSEEKKEFLVEADVAEDKGARHTMEDVWVVLPDASLDFPGTLRCAHFAIYDGHGGRLAAEFAKKHLHLNVLSAGLPRELLDVKVAKKAILEGFRKTDELLLQKSVSGGWQDGATAVCVWILDQKVFVANIGDAKAVLARSSTTNELGNHTEAGNPLKAIVLTREHKAIYPQERSRIQKSGGVISSNGRLQGRLEVSRAFGDRHFKKFGVSATPDIHAFELTERENFMILGCDGLWEVFGPSDAVGFVQKLLKEGLHVSTVSRRLVKEAVKERRCKDNCTAIVIVFKRV", "length": 351 }, "evidence": [ { "id": "E1BYA9", "url": "https://omabrowser.org/oma/group/E1BYA9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z1Z6-1", "protein_name": "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "gene_name": "Ilkap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLFGDLPEPERPPRPSAGKEAQEGPVLFEDLPPTSSTDSGSGGPLLFDGLPPAGSGNSGSLATSGSQVVKNEGKGAKRKAPEEEKNGGEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITQECNPPSSLITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRDGRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKIQTREGKPAVDARYEAACNRLANKAVQRGSADNVTVMVVRIGH", "length": 392 }, "evidence": [ { "id": "E1BYA9", "url": "https://omabrowser.org/oma/group/E1BYA9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "E1BYA9", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] } ] }, { "uniprot_ac": "A0A8V1A6D3", "gene_name": "DUSP8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A6D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A6D3" } ] } ] }, { "uniprot_ac": "A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1AK42", "gene_name": "DUSP23", "activity": [ { 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"id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] } ] }, { "uniprot_ac": "E1BVM8", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] } ] }, { "uniprot_ac": "E1BYA9", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NC58", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NJB8", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] } ] }, { "uniprot_ac": "F1NXH3", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] } ] }, { "uniprot_ac": "P48463", "gene_name": "PPP2CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48463" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48463", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48463" } ] } ] }, { "uniprot_ac": "P62207", "gene_name": "PPP1CB", "activity": [ { "ec_number": "3.1.3.53", "activity": "O-phospho-L-threonyl-[myosin light chain] + H2O = L-threonyl-[myosin light chain] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] } ] }, { "uniprot_ac": "Q5F3Z7", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] } ] }, { "uniprot_ac": "Q5ZJJ8", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] } ] }, { "uniprot_ac": "Q5ZJQ7", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] } ] }, { "uniprot_ac": "Q9PTJ6", "gene_name": "NFI1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": 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"Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] } ] }, { "uniprot_ac": "Q9YHA0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BYA9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 389, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BYA9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BYA9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 387, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 379, "end_pos": 381 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BYK8-1", "uniprot_ac": "E1BYK8", "uniprot_id": "E1BYK8_CHICK", "mass": { "chemical_mass": 46941.0, "monoisotopic_mass": 46941.0 }, "refseq": { "ac": "XP_417758", "name": "glycoprotein endo-alpha-1,2-mannosidase-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417758" }, "gene_names": [ { "name": "MANEAL", "type": "recommended", "evidence": [ { "id": "E1BYK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYK8" } ] }, { "name": "MANEAL", "type": "synonym", "evidence": [ { "id": "XP_417758", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417758" } ] } ], "protein_names": [ { "name": "Mannosidase endo-alpha like", "type": "synonym", "evidence": [ { "id": "E1BYK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYK8/entry#names_and_taxonomy" } ] }, { "name": "glycoprotein endo-alpha-1,2-mannosidase-like protein", "type": "synonym", "evidence": [ { "id": "XP_417758", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417758" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052554.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_417758.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417758" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYK8", "url": "https://www.uniprot.org/uniprotkb/E1BYK8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MANEAL", "url": "https://www.uniprot.org/uniprotkb/E1BYK8", "locus": { "chromosome": "23", "start_pos": 3932027, "end_pos": 3935896, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013284", "url": "https://www.ensembl.org/id/ENSGALG00010013284" } ] } } ], "crossref": [ { "id": "E1BYK8", "url": "https://alphafold.ebi.ac.uk/entry/E1BYK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001653", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001653", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11574", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11574", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419611", "url": "https://www.ncbi.nlm.nih.gov/gene/419611", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419611", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VHWDHVM", "url": "https://omabrowser.org/oma/group/VHWDHVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BYK8", "url": "https://www.orthodb.org/?gene=E1BYK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13572", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13572", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13572:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13572:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417758", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BYK8", "url": "https://www.uniprot.org/uniprotkb/E1BYK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYK8-1", "url": "https://www.uniprot.org/uniprotkb/E1BYK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRRRRRGGLALLLAALFVFGTVLALRTLRAADALPAGAPGLAEPPAPPGAREPAAGSGPSYDLHAFYYAWYGSPRFEGRYLHWDHALVPHWDPKVSASYPRGRHRPPDDIGSSFYPALGPYSSRDPAVVDEHMGQLRAAAIGVLVLSWYPPGLADDNGEPSDSLVPFILDAAQRYAIKVTFHIQPYKGRDDHTVHENIKYIMDKYGSHAAFYKYKTSTGRSLPLFYIYDSYLTPAESWANLLTPSGSHSLRNTAYDAVFIALLVEEGHKEDILSAGYDGMYTYFASNGFSFGSSHQNWKAIKTFCDSNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAVPKKTLTRLYLDYLPHQPNMYLELTRRWAEHFSKEKEQWLM", "length": 416, "header": "tr|E1BYK8-1|E1BYK8_CHICK Isoform 1 of Mannosidase endo-alpha like OS=Gallus gallus OX=9031 GN=MANEAL PE=3 SV=4 CANONICAL=E1BYK8-1" }, "isoforms": [ { "isoform_ac": "E1BYK8-1", "url": "https://www.uniprot.org/uniprotkb/E1BYK8/entry#E1BYK8-1", "sequence": { "sequence": "MRRRRRRGGLALLLAALFVFGTVLALRTLRAADALPAGAPGLAEPPAPPGAREPAAGSGPSYDLHAFYYAWYGSPRFEGRYLHWDHALVPHWDPKVSASYPRGRHRPPDDIGSSFYPALGPYSSRDPAVVDEHMGQLRAAAIGVLVLSWYPPGLADDNGEPSDSLVPFILDAAQRYAIKVTFHIQPYKGRDDHTVHENIKYIMDKYGSHAAFYKYKTSTGRSLPLFYIYDSYLTPAESWANLLTPSGSHSLRNTAYDAVFIALLVEEGHKEDILSAGYDGMYTYFASNGFSFGSSHQNWKAIKTFCDSNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAVPKKTLTRLYLDYLPHQPNMYLELTRRWAEHFSKEKEQWLM", "length": 416, "header": "tr|E1BYK8-1|E1BYK8_CHICK Isoform 1 of Mannosidase endo-alpha like OS=Gallus gallus OX=9031 GN=MANEAL PE=3 SV=4 CANONICAL=E1BYK8-1" }, "locus": { "chromosome": "23", "start_pos": 3935755, "end_pos": 3933303, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031942.1", "url": "https://www.ensembl.org/id/ENSGALT00010031942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018735.1", "url": "https://www.ensembl.org/id/ENSGALP00010018735.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419611", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419611", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABM7-1", "protein_name": "Mannosidase endo-alpha like", "gene_name": "MANEAL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARRRRRACIALFLVLLFAFGTLMGLRTLKAPDGLPALGPGLELAPFERRPEGAPAPAARAPAAPAAPPPPQPPPRTAGPGSSLGPAPAEAEPAPGQSLRVYSDLHAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSSRDPEVLREHMTQLKEAAIGVLVLSWYPPGMADDNGEPSDDLVPAILDTAHQYNIQVAFHIQPYKGRDDITLHDNVKYIIDTYGSHGAFYRYKNSMGKSLPLFYIYDSYLTSPEAWAHLLTPNGPHSIRNTPYDGVFIALLVEEGHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDANNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAIPKKTPTRLYLDYLPHQPSLYLELTRRWAEHFIKEKEQWLM", "length": 457 }, "evidence": [ { "id": "E1BYK8", "url": "https://omabrowser.org/oma/group/E1BYK8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0KXB0-1", "protein_name": "Mannosidase, endo-alpha-like", "gene_name": "Maneal", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARRRRRACIALFLVLLFAFGTLMGLRTLKAPDGLPALGPGPELAPFERRPEGNPAPARAPAAPAAPPPPPPRTAAPRASLGPVEADPAPRQSQRVYSDLHAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSSRDPDVLREHMIQLKEAAIGVLVLSWYPPGMADDNGEPTDDLVPAILDSAHQYNIQVAFHIQPYKGRDDITVHDNIKYIIDTYGSHGAFYRYKNSMGKSLPLFYIYDSYLTSPEAWAHLLTQNGPHSIRNTPYDGVFIALLVEESHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDTNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAVPKTTPTRLYLDYLPHQPSLYLELTRRWAEHFIKEKEQWLM", "length": 452 }, "evidence": [ { "id": "E1BYK8", "url": "https://omabrowser.org/oma/group/E1BYK8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VSG8-1", "protein_name": "Glycoprotein endo-alpha-1,2-mannosidase-like protein", "gene_name": "MANEAL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARRRRRACIALFLVLLFAFGTLMGLRTLKAPDGLPALGPGLELAPFERRPEGAPAPAARAPAAPAAPPPPPPPPRTADPGGSPGPAPAEAEPAPVQSLRVYSDLHAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSSRDPEVLREHMTQLKEAAIGVLVLSWYPPGMADDNGEPSDDLVPAILDTAHQYSIQVAFHIQPYKGRDDITVHDNIKYIIDTYGSHGAFYRYKNSMGKSLPLFYIYDSYLTSPEAWAHLLTPNGPHSIRNTPYDGVFIALLVEEGHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDANNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAIPKKTPTRLYLDYLPHQPSLYLELTRRWAEHFIKEKEQWLM", "length": 457 }, "evidence": [ { "id": "E1BYK8", "url": "https://omabrowser.org/oma/group/E1BYK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P1J0-1", "protein_name": "Glycoprotein endo-alpha-1,2-mannosidase-like protein", "gene_name": "Maneal", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARRRRRACIALFLVLLFAFGTLMGLRTLKAPDGLPALGPGPELAPFERRPEGNPAPARAPAAPAAPPPPPPRTAAPRASLGPAEADPAPRQSLRVYSDLHAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSSRDPDVLREHMTQLKEAAIGVLVLSWYPPGMADDNGEPTDDLVPAILDTAHQYNIQVAFHIQPYKGRDDITVHDNIKYIIDTYGSHGAFYRYKNSMGKSLPLFYIYDSYLTSPEAWAHLLTQNGPHSIRNTPYDGVFIALLVEESHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDTNNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAVPKTTPTRLYLDYLPHQSSLYLELTRRWAEHFIKEKEQWLM", "length": 452 }, "evidence": [ { "id": "E1BYK8", "url": "https://omabrowser.org/oma/group/E1BYK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1BYK8", "url": "https://www.uniprot.org/uniprotkb/E1BYK8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "alpha-mannosidase activity", "id": "GO:0004559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004559", "evidence": [ { "database": "UniProtKB", "id": "E1BYK8", "url": "https://www.uniprot.org/uniprotkb/E1BYK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BYK8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 416, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BYK8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BYK8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_416855.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416855" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYN0", "url": "https://www.uniprot.org/uniprotkb/E1BYN0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC418658", "url": "https://www.uniprot.org/uniprotkb/E1BYN0", "locus": {} } ], "crossref": [ { "id": "E1BYN0", "url": "https://alphafold.ebi.ac.uk/entry/E1BYN0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016648", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016648", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418658", "url": "https://www.ncbi.nlm.nih.gov/gene/418658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418658", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AAKWRDW", "url": 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"MIAVLPCTAIAAILFRTYFLMALTSCLLWNIFGFSTAVDSKPNILLFLADDLGIGDVGCYGNNTIRTPNIDRLAREGVKLTQHIAAAPLCTPSRAAFLTGRYPIRSGMASSNRYRALQWNAGSGGLPANETTFARLLQQQGYTTGLIGKWHQGVNCESFSDHCHHPLNHGFDYFYGMLFTLLNNCQENKPPELDVALQAKLWLYSQIIAFAVLTLAAGRLTGLVSIRWKIIACFTLAGCLFFISWYSSYGFVQRWNCILMRNHDITEQPMRLERTASLMLKEAISFIKRNRNGPFLLFVSFLHVHTPLFTTVKFLGKSHHGLYGDNVEEMDWMVGKILDLLDKEGLKNHTFTYFASDHGGHLEAQDGSAQMGGWNGIYKGGKGMGGWEGGIRVPGVFRWPGVLPAGTVINEPTSLMDIFPTVVHLAGGILPQDRVIDGRNLMPLLQGRTQKSEHKFLFHYCGSYLHAVRWHQKDSGAVWKAHYVTPNFHPLGAGACYGKGICPCFGEGVTHHDPPLLYDLSRDPSESQPLSADTEPLFDTVIEQIGRAIEEHRRTLTAVPQQLSLYNIIWKPWLQPCCGTFPFCWCDKEGDSTQSL", "length": 596, "header": "tr|E1BYN0-1|E1BYN0_CHICK Isoform 1 of Sulfatase N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC418658 PE=3 SV=1 CANONICAL=E1BYN0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PK90-1", "url": "https://www.uniprot.org/uniprotkb/E1BYN0/entry#A0A1D5PK90-1", "sequence": { "sequence": "MIAVLPCTAIAAILFRTYFLMALTSCLLWNIFGFSTAVDSKPNILLFLADDLGIGDVGCYGNNTIRTPNIDRLAREGVKLTQHIAAAPLCTPSRAAFLTGRYPIRSGMASSNRYRALQWNAGSGGLPANETTFARLLQQQGYTTGLIGKWHQGVNCESFSDHCHHPLNHGFDYFYGMLFTLLNNCQENKPPELDVALQAKLWLYSQIIAFAVLTLAAGRLTGLVSIRWKIIACFTLAGCLFFISWYSSYGFVQRWNCILMRNHDITEQPMRLERTASLMLKEAISFIKRNRNGPFLLFVSFLHVHTPLFTTVKFLGKSHHGLYGDNVEEMDWMVGGKGMGGWEGGIRVPGVFRWPGVLPAGTVINEPTSLMDIFPTVVHLAGGILPQDRVIDGRNLMPLLQGRTQKSEHKFLFHYCGSYLHAVRWHQKDSGAVWKAHYVTPNFHPLGAGACYGKGICPCFGEGVTHHDPPLLYDLSRDPSESQPLSADTEPLFDTVIEQIGRAIEEHRRTLTAVPQQLSLYNIIWKPWLQPCCGTFPFCWCDKEGDSTQSL", "length": 551, "header": "tr|A0A1D5PK90-1|A0A1D5PK90_CHICK Computationally mapped isoform of Sulfatase N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC418658 PE=3 SV=1 CANONICAL=E1BYN0-1" }, "locus": { "chromosome": "1", "start_pos": 128596891, "end_pos": 128585654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005095.1", "url": "https://www.ensembl.org/id/ENSGALT00010005095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003007.1", "url": "https://www.ensembl.org/id/ENSGALP00010003007.1" } ] } }, { "isoform_ac": "E1BYN0-1", "url": "https://www.uniprot.org/uniprotkb/E1BYN0/entry#E1BYN0-1", "sequence": { "sequence": "MIAVLPCTAIAAILFRTYFLMALTSCLLWNIFGFSTAVDSKPNILLFLADDLGIGDVGCYGNNTIRTPNIDRLAREGVKLTQHIAAAPLCTPSRAAFLTGRYPIRSGMASSNRYRALQWNAGSGGLPANETTFARLLQQQGYTTGLIGKWHQGVNCESFSDHCHHPLNHGFDYFYGMLFTLLNNCQENKPPELDVALQAKLWLYSQIIAFAVLTLAAGRLTGLVSIRWKIIACFTLAGCLFFISWYSSYGFVQRWNCILMRNHDITEQPMRLERTASLMLKEAISFIKRNRNGPFLLFVSFLHVHTPLFTTVKFLGKSHHGLYGDNVEEMDWMVGKILDLLDKEGLKNHTFTYFASDHGGHLEAQDGSAQMGGWNGIYKGGKGMGGWEGGIRVPGVFRWPGVLPAGTVINEPTSLMDIFPTVVHLAGGILPQDRVIDGRNLMPLLQGRTQKSEHKFLFHYCGSYLHAVRWHQKDSGAVWKAHYVTPNFHPLGAGACYGKGICPCFGEGVTHHDPPLLYDLSRDPSESQPLSADTEPLFDTVIEQIGRAIEEHRRTLTAVPQQLSLYNIIWKPWLQPCCGTFPFCWCDKEGDSTQSL", "length": 596, "header": "tr|E1BYN0-1|E1BYN0_CHICK Isoform 1 of Sulfatase N-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC418658 PE=3 SV=1 CANONICAL=E1BYN0-1" }, "locus": { "chromosome": "1", "start_pos": 128596891, "end_pos": 128585654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005093.1", "url": "https://www.ensembl.org/id/ENSGALT00010005093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003005.1", "url": "https://www.ensembl.org/id/ENSGALP00010003005.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418658", "resource": "KEGG Pathway" }, { "id": "R-GGA-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-GGA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { 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"https://www.uniprot.org/uniprotkb/E1BYN0" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1BYN0", "url": "https://www.uniprot.org/uniprotkb/E1BYN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BYN0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 596, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BYN0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BYN0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BYN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYN0" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 427, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 62, "end_pos": 64 } ] }, 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BYR4-1", "uniprot_ac": "E1BYR4", "uniprot_id": "E1BYR4_CHICK", "mass": { "chemical_mass": 48851.0, "monoisotopic_mass": 48851.0 }, "refseq": { "ac": "XP_024999958", "name": "pre-mRNA-splicing factor CWC25 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999958" }, "gene_names": [ { "name": "CWC25", "type": "recommended", "evidence": [ { "id": "E1BYR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYR4" } ] }, { "name": "CWC25", "type": "synonym", "evidence": [ { "id": "XP_024999958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999958" } ] } ], "protein_names": [ { "name": "CWC25 spliceosome associated protein homolog", "type": "synonym", "evidence": [ { "id": "E1BYR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYR4/entry#names_and_taxonomy" } ] }, { "name": "pre-mRNA-splicing factor CWC25 homolog", "type": "synonym", "evidence": [ { "id": "XP_024999958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999958" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999958" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYR4", "url": "https://www.uniprot.org/uniprotkb/E1BYR4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CWC25", "url": "https://www.uniprot.org/uniprotkb/E1BYR4", "locus": { "chromosome": "27", "start_pos": 4021409, "end_pos": 4026397, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022158", "url": "https://www.ensembl.org/id/ENSGALG00010022158" } ] } } ], "crossref": [ { "id": "E1BYR4", "url": "https://alphafold.ebi.ac.uk/entry/E1BYR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001624", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001624", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420000", "url": "https://www.ncbi.nlm.nih.gov/gene/420000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420000", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SWHPHTM", "url": "https://omabrowser.org/oma/group/SWHPHTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BYR4", "url": "https://www.orthodb.org/?gene=E1BYR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16196:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16196:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10197", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10197", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12542", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12542", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024999958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999958", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BYR4", "url": "https://www.uniprot.org/uniprotkb/E1BYR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYR4-1", "url": "https://www.uniprot.org/uniprotkb/E1BYR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKYEAERKKIEELQRELQEERAREEMQRYAEDMGTVRKREEKLEWMYQGPGGMVNREEYLMGRPVDKYVFEKTEDKDAGCSNETGLLPGSIFAKSGANSVLDMANKIREDPLFMIRKREEEKKREVLNNPVKMKKIKELLQNSLDKKEKKKKKEKKKKHKKHRRHSSSSESASSDEERSKARSQKKTNNSSWKPIPSKVPGYGLQVRDSDRNHRSRSSPVAGQGRTPHKHREHSRSRSTSRSPQRCTGKKSTEPSGCRGSRSPSRHSKQHSSREEKGKARSPSPKKSYRRQHIPGYTRKISAEELERKRQEMMENAKWREEERVNNLKKHRKEEELERELEKLDSRDGKFLHNFKLESASTSTLEDRVKRNIHSLQRTPAALEKNFMQR", "length": 416, "header": "tr|E1BYR4-1|E1BYR4_CHICK Isoform 1 of CWC25 spliceosome associated protein homolog OS=Gallus gallus OX=9031 GN=CWC25 PE=3 SV=2 CANONICAL=E1BYR4-1" }, "isoforms": [ { "isoform_ac": "E1BYR4-1", "url": "https://www.uniprot.org/uniprotkb/E1BYR4/entry#E1BYR4-1", "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKYEAERKKIEELQRELQEERAREEMQRYAEDMGTVRKREEKLEWMYQGPGGMVNREEYLMGRPVDKYVFEKTEDKDAGCSNETGLLPGSIFAKSGANSVLDMANKIREDPLFMIRKREEEKKREVLNNPVKMKKIKELLQNSLDKKEKKKKKEKKKKHKKHRRHSSSSESASSDEERSKARSQKKTNNSSWKPIPSKVPGYGLQVRDSDRNHRSRSSPVAGQGRTPHKHREHSRSRSTSRSPQRCTGKKSTEPSGCRGSRSPSRHSKQHSSREEKGKARSPSPKKSYRRQHIPGYTRKISAEELERKRQEMMENAKWREEERVNNLKKHRKEEELERELEKLDSRDGKFLHNFKLESASTSTLEDRVKRNIHSLQRTPAALEKNFMQR", "length": 416, "header": "tr|E1BYR4-1|E1BYR4_CHICK Isoform 1 of CWC25 spliceosome associated protein homolog OS=Gallus gallus OX=9031 GN=CWC25 PE=3 SV=2 CANONICAL=E1BYR4-1" }, "locus": { "chromosome": "27", "start_pos": 4026045, "end_pos": 4022152, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053910.1", "url": "https://www.ensembl.org/id/ENSGALT00010053910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032464.1", "url": "https://www.ensembl.org/id/ENSGALP00010032464.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420000", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZKR9-1", "protein_name": "CWC25 spliceosome associated protein homolog", "gene_name": "CWC25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLVKKEKKKKKEKKKKHKKHKHRGSSSDRCSSEDERGRGRSQKKLANSSPVLAKVPGYGLQLRNSDRSQGPRGPPVAEQRAGHGLKNYSRSRSSSPSPPRHASKKSTREAGSRDRRSRSPGRRSRSPRPSKPHNSKVSRRDRGRTKSPSPKKEVYQRRHAPGYTRKLSSEELERKRQEMMENAKWREAERLNILKRHAKDDEREQRLQKLDSRDGKFLHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR", "length": 425 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MER3-1", "protein_name": "CWC25 spliceosome associated protein homolog", "gene_name": "CWC25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSGSDRCSSEDERSRGRSQKKMANSPPVLSKVPGYGLQVRNSDHSQGLQGSLMAERKGAHGLKNYSRSRSSSSSPPRHTSKKSTREAGSRDRRSRSPCRRSRSPRPSKPHNSKGNRKDRGRSKSPSPKKEVYQRRHAPGYTRKLSSEELERKRQEMMENAKWREEERLNILKRHAKDDEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR", "length": 425 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H5W3-1", "protein_name": "Pre-mRNA-splicing factor CWC25 homolog", "gene_name": "Cwc25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDGSSSEEEHSQGRSQKKMANSFPVLSKVPGYGLQVRDSDRNQGLQGSLMAEQRGVKNHSRSRSSSHSPPRHVSKKSSKEERSRDRRSRSPGRRSRSPRPSKPHASKVNRKERDSPSPKKEVYQRRHSSGYTRKLSAEELERKRQEMMENAKWREEERLNTLKRHAKEDERERRLEKLDSRSGKFIHRMKLESASTSSLEDRVKRNIHSLQRTSVALEKNFMKR", "length": 419 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3V6I3-1", "protein_name": "CWC25 spliceosome-associated protein homolog", "gene_name": "Cwc25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVSRDEYLLGRPIDKYVFEKMEEREAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMRKIKELLQMSLEKKEKKKKKEKKKKHRKHKHRSSSSDRSSSEDEQSHGRSQKKMANSFPVLSKVPGYGLQVRDSDRNQGLQGSLGEQRAVKNHSRSSSSPARHASRKSTKEERSRDRRSRSPGRKSLSPRPSKQHTSKANRKERDSPSPKKEVYQRRHASGYTRKLSAEELERKRQEMMENAKWREEERLNTLKRHAKEDEQEHRLERLDSRSGKFIHRMKLESASTSSLEDRVKRNIHSLQRTSMALEKNFMRR", "length": 415 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O64855-1", "protein_name": "Pre-mRNA splicing factor domain-containing protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGMKFLNKKGWHTGSLRNIETVWKAEQKQEAEQKKLEELRLQILQERERSEFRALQEQAGLIPRQERLEFLYDSGLAVGKGSASGSGVSFQKEEQPLAKSEAGSSASEKPDQSAPGALFEEKAQSANDSWRKLHSDPLLLIRQREQEALAKIKNNPVKMALIRKSVEEKGKGKDGDTKEHKKKHKRKSGKHQKQSSSRQRSDSEEDSGEENNGRKSHHQKTSGTHDRHYERPRSDLEDESKGRESRDRHYEKRRSELDDGHKRRERHDTHYERRRSEMDDESKRRESRDNHYERRRSDLDDESKRRESHDKHFERQRSDLDDEYKRRESQDKRRRSDIDDEPKRRDARPNEKYRNRSPKGGVERENLKSYGQEDKKRKAEDLDSGKPNEYQNRRRKGGSKLSEEERAARLKQMQMDAEVHEEQRWTRLKKADETDAVEADKNKVSTGKSFLDDANKSVYGVEKGGSSTIEESVRRRSYYSQRGTAAEGNAFRR", "length": 493 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54QF2-1", "protein_name": "CBF1-interacting co-repressor CIR N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKSFLSKKSWHVSTMKNQERIWKAEKEKEDEQKKIDQLKKEMREEEQIRDLKNQFNEASGKYVKPDNKMDWMYEGAFQLSMKKTETVDDYLLGKKIDDSAEDIIKKAAQLPGALFLHSNSNDNPQDIKSLVREDPLMIIERKKQEALDKIMNNPLQMKKLEKEKKESDKILKKLKKKEKNEKKEKKEKKEKKEKKEKKKDKNYSSDDDDDDDDDNNDSENDKEKTEKKKDKYKDKDKNNEKIQNSNGHTEKPKNYNDNGGRVDDERRDDRYRDRDHSDRRDDRNRDSEKEKERERRDDRDRDRERNRDSHYDRRDDRDRDRDRDRDRRDERERRDDRDRERNRDHHYDRDRDRRDDRDRRDDKDRDTYHHHHHHHQERRDDRYRDRDHSDRYYDRNRRDEKDHHIDKKREDSRYRDRDHNDSPNKKRDRNDYENRPSNGGLSEEEKRKRIEEMKQSGLQREEERLKKSKNDEDEKDYVPKSLEDRGKTFLEYVF", "length": 495 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DBF7-1", "protein_name": "Pre-mRNA-splicing factor CWC25 homolog", "gene_name": "Cwc25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEREAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHRKHKHRSSSSGGSSSEDEQSQARSQKKMANSFPVLSKVPGYGLQVRDSDRNRGLQGSLGEQRAIKNNSRSRSSSPPRHASKKSTKEERPRDRRSRSPSRRSRSPRPSKPHTSKVNRKERDSPSPKKEAYQRRHASGYTRKLSAEELERKRQEMMENAKWREEERLNTLKRHAREDEREHRLERLDSRSGKFLHRMKLESASTSSLEDRVKRNIHSLQRTSVALEKNFMRR", "length": 416 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXE8-1", "protein_name": "Pre-mRNA-splicing factor CWC25 homolog", "gene_name": "CWC25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGGDLNLKKSWHPQTLRNVEKVWKAEQKHEAERKKIEELQRELREERAREEMQRYAEDVGAVKKKEEKLDWMYQGPGGMVNRDEYLLGRPIDKYVFEKMEEKEAGCSSETGLLPGSIFAPSGANSLLDMASKIREDPLFIIRKKEEEKKREVLNNPVKMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDEHSAGRSQKKMANSSPVLSKVPGYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPPRHASKKSTREAGSRDRRSRSLGRRSRSPRPSKLHNSKVNRRETGQTRSPSPKKEVYQRRHAPGYTRKLSAEELERKRQEMMENAKWREEERLNILKRHAKDEEREQRLEKLDSRDGKFIHRMKLESASTSSLEDRVKRNIYSLQRTSVALEKNFMKR", "length": 425 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQF5-1", "protein_name": "Cwc25", "gene_name": "Cwc25", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGGDLNLKKSWHPHTMKNQERVWKAEEQAKMEERKLQDLRKEINEERDREELRRLGESSGVLSNNGGAAGEAKLEWMYKNSTELINREEYLLGRKIDKSFETLQAEESRQEQNTVGLKQTINHVEHDCVPFSIRTYRNVQSNEQVDIQRKTLEDPLMLIKQREMESRRKLLENPVKLKEIHRILKTEQEQKAAEGKKKNKKNKKSKKSKKKKKNRRSSNEESSDSESNDSDDDLDRKLARQVSKLKGDQGDLKLDKLLDAKYRTISNQLDMATKKKKSKKSKKKKSSDSSDESSDEEEEPRRKHKRSHSSEDRNQRERRRSRSPRDRKKRQSRSPEQRQRQRSPEERRERRRSRSRSPLARRQRRTRSPEDRKARRQSKDTSKQREKRRSRTPEERSRSKRSRSRSSKGDDKRRIAERPPPSRPTGKPKLSEADREARLREMMDNATWREADRSQVVRKHREAYAREEAQNRERDFDKEFINKEVKKAIANHNSIGDRIRANLNNIQRTASSMDSNFARK", "length": 521 }, "evidence": [ { "id": "E1BYR4", "url": "https://omabrowser.org/oma/group/E1BYR4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BYR4", "url": "https://www.uniprot.org/uniprotkb/E1BYR4" } ], "pmid": "" }, { "name": "U2-type catalytic step 1 spliceosome", "id": "GO:0071006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071006", "evidence": [ { "database": "UniProtKB", "id": "E1BYR4", "url": "https://www.uniprot.org/uniprotkb/E1BYR4" } ], "pmid": "" }, { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "E1BYR4", "url": "https://www.uniprot.org/uniprotkb/E1BYR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "E1BYR4", "url": "https://www.uniprot.org/uniprotkb/E1BYR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BYR4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 416, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BYR4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BYR4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BYR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYR4" }, { "id": "SM01083", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01083" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBF1-interacting co-repressor CIR N-terminal", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 47, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"evidence": [ { "id": "E1BYY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYY6" } ] }, { "name": "LRRC3B", "type": "synonym", "evidence": [ { "id": "XP_015137278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137278" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 3", "type": "recommended", "evidence": [ { "id": "E1BYY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYY6/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 3B", "type": "synonym", "evidence": [ { "id": "XP_015137278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137278" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137278" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BYY6", "url": "https://www.uniprot.org/uniprotkb/E1BYY6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC3B", "url": "https://www.uniprot.org/uniprotkb/E1BYY6", "locus": { "chromosome": "2", "start_pos": 38134743, "end_pos": 37979910, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002527", "url": "https://www.ensembl.org/id/ENSGALG00010002527" } ] } } ], "crossref": [ { "id": "ENSGALG00000011314", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011314", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420657", "url": "https://www.ncbi.nlm.nih.gov/gene/420657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420657", "url": 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OS=Gallus gallus OX=9031 GN=LRRC3B PE=3 SV=3 CANONICAL=E1BYY6-1" }, "isoforms": [ { "isoform_ac": "E1BYY6-1", "url": "https://www.uniprot.org/uniprotkb/E1BYY6/entry#E1BYY6-1", "sequence": { "sequence": "MHLVDLWLTRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSHSGGLNVSCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMAVNHETANNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKPDEADDISTVV", "length": 259, "header": "tr|E1BYY6-1|E1BYY6_CHICK Isoform 1 of Leucine-rich repeat-containing protein 3 OS=Gallus gallus OX=9031 GN=LRRC3B PE=3 SV=3 CANONICAL=E1BYY6-1" }, "locus": { "chromosome": "2", "start_pos": 38127542, "end_pos": 38126766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005800.1", "url": "https://www.ensembl.org/id/ENSGALT00010005800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003603.1", "url": "https://www.ensembl.org/id/ENSGALP00010003603.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420657", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420657", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KNN3-1", "protein_name": "Leucine-rich repeat-containing protein 3B", "gene_name": "lrrc3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTPLDLWLSRSIPMCLLLQSLVLMVLCFPSASTCPKGCTCQRSESPPHGLNVTCSLSRLKEIPPDVPPDTQLLQLDRNHISLVPDRIFHGLRMLRRLNLSHNAVETLGEGAFIGLEGSLEVLDLSYNRITSVHKDAFARLKARVVVDNNPWHCDCALQQALGGMAHNHERVLCRSSELRDQEGQPFMAVDADLCNLAKRTTDYAMLVTMFGWFAMVISYVVYYVRQNQEDARRHLEYLKSLPSKPKKPDEPEDISTVV", "length": 258 }, "evidence": [ { "id": "E1BYY6", "url": "https://omabrowser.org/oma/group/E1BYY6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6H789-1", "protein_name": "Leucine-rich repeat-containing protein 3B", "gene_name": "LRRC3B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLVDLWLTRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMVSNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV", "length": 259 }, "evidence": [ { "id": "E1BYY6", "url": "https://omabrowser.org/oma/group/E1BYY6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A9I7-1", "protein_name": "Leucine rich repeat containing 3B", "gene_name": "Lrrc3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLVDLWLSRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV", "length": 259 }, "evidence": [ { "id": "E1BYY6", "url": "https://omabrowser.org/oma/group/E1BYY6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F2Z5C4-1", "protein_name": "Leucine rich repeat containing 3B", "gene_name": "LRRC3B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLVDLWLTRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV", "length": 259 }, "evidence": [ { "id": "E1BYY6", "url": "https://omabrowser.org/oma/group/E1BYY6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H4L3-1", "protein_name": "Leucine-rich repeat-containing protein 3B", "gene_name": "Lrrc3b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNLVDLWLSRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDVSTVV", "length": 259 }, "evidence": [ { "id": "E1BYY6", "url": "https://omabrowser.org/oma/group/E1BYY6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8VCH9-1", "protein_name": "Leucine-rich repeat-containing protein 3B", "gene_name": "Lrrc3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLVDLWLSRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV", "length": 259 }, "evidence": [ { "id": "E1BYY6", "url": 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"E1BYY6", "url": "https://www.uniprot.org/uniprotkb/E1BYY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "E1BYY6", "url": "https://www.uniprot.org/uniprotkb/E1BYY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BYY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYY6" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BZ46-1", "uniprot_ac": "E1BZ46", "uniprot_id": "E1BZ46_CHICK", "mass": { "chemical_mass": 18404.0, "monoisotopic_mass": 18404.0 }, "refseq": { "ac": "NP_001264299", "name": "epithelial membrane protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264299" }, "gene_names": [ { "name": "EMP1", "type": "recommended", "evidence": [ { "id": "E1BZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ46" } ] }, { "name": "EMP1", "type": "synonym", "evidence": [ { "id": "NP_001264299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264299" } ] } ], "protein_names": [ { "name": "Epithelial membrane protein 1", "type": "recommended", "evidence": [ { "id": "E1BZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ46/entry#names_and_taxonomy" } ] }, { "name": "epithelial membrane protein 1", "type": "synonym", "evidence": [ { "id": "NP_001264299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264299" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888493.178705.1, BX930381.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Apr 5, 2013 this sequence version replaced XP_416203.1. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264299" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZ46", "url": "https://www.uniprot.org/uniprotkb/E1BZ46" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EMP1", "url": "https://www.uniprot.org/uniprotkb/E1BZ46", "locus": { "chromosome": "1", "start_pos": 48382889, "end_pos": 48366939, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011080", "url": "https://www.ensembl.org/id/ENSGALG00010011080" } ] } } ], "crossref": [ { "id": "E1BZ46", "url": "https://alphafold.ebi.ac.uk/entry/E1BZ46", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011803", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011803", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417964", "url": "https://www.ncbi.nlm.nih.gov/gene/417964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417964", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417964", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWMCILI", "url": "https://omabrowser.org/oma/group/CWMCILI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BZ46", "url": "https://www.orthodb.org/?gene=E1BZ46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264299", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BZ46", "url": "https://www.uniprot.org/uniprotkb/E1BZ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ46-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVLLAGIFVVHIATVIMLFVSTIANVWMVGRSSLGNVSWGLWMYCNNTCEPLTLSGDNEPSLKAAQAFMILSIIFSVIALVTFIVQLFTLEKGKRFYITGAITLVCWLCILIGVSIYTARFTDSQSVSQITLISSHHGYSFILAWICFCFSFIIGILYLVLRKK", "length": 165, "header": "tr|E1BZ46-1|E1BZ46_CHICK Isoform 1 of Epithelial membrane protein 1 OS=Gallus gallus OX=9031 GN=EMP1 PE=3 SV=1 CANONICAL=E1BZ46-1" }, "isoforms": [ { "isoform_ac": "E1BZ46-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ46/entry#E1BZ46-1", "sequence": { "sequence": "MLVLLAGIFVVHIATVIMLFVSTIANVWMVGRSSLGNVSWGLWMYCNNTCEPLTLSGDNEPSLKAAQAFMILSIIFSVIALVTFIVQLFTLEKGKRFYITGAITLVCWLCILIGVSIYTARFTDSQSVSQITLISSHHGYSFILAWICFCFSFIIGILYLVLRKK", "length": 165, "header": "tr|E1BZ46-1|E1BZ46_CHICK Isoform 1 of Epithelial membrane protein 1 OS=Gallus gallus OX=9031 GN=EMP1 PE=3 SV=1 CANONICAL=E1BZ46-1" }, "locus": { "chromosome": "1", "start_pos": 48381382, "end_pos": 48379267, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026520.1", "url": "https://www.ensembl.org/id/ENSGALT00010026520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015103.1", "url": "https://www.ensembl.org/id/ENSGALP00010015103.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417964", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417964", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V7Y2-1", "protein_name": "Epithelial membrane protein 1", "gene_name": "EMP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLVLLAGIFVVHIATVVMLFVCTIANVWVVSDAGQGSVGLWKNCTSAGCTDTLLYGGEDALKSVQAFMILSIIFSVVSLVVFVFQLFTMEKGNRFFLSGATMLVCWLCIMVGASIYTHHYANSSKNQYSASHHGYSFILAWICFCFSFIIGVLYLVLRKK", "length": 160 }, "evidence": [ { "id": "E1BZ46", "url": "https://omabrowser.org/oma/group/E1BZ46/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9S455-1", "protein_name": "Epithelial membrane protein 1", "gene_name": "EMP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLVLLASIFVVHIATVIMLFVSTIANVWVVSDLGTGSVGLWKNCTSGGCGDNLSYAGEDALKAVQAFMILSIIFSVISLVVFVFQLFTMEKGNRFFLSGATMLVCWLCVMVGASIYTHHYANGSINNYEPSHHGYSFILTWICFCFSFIIGILYLVLRKK", "length": 160 }, "evidence": [ { "id": "E1BZ46", "url": "https://omabrowser.org/oma/group/E1BZ46/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HLA5-1", "protein_name": "Epithelial membrane protein 1", "gene_name": "Emp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLVLLAGIFVVHIATAIMLFVSTISNVWMVSSDVKSSVGLWKNCTNGNCGGSLVYGNEDALKAVQAFMILSIIFSVISLVVFVFQLFTMEKGNRFFLSGSTMLVCWFCILVGVSIYTHHYAHRDVNITANDHQGYCFILTWICFCFSFIIGILYMVLRKK", "length": 160 }, "evidence": [ { "id": "E1BZ46", "url": "https://omabrowser.org/oma/group/E1BZ46/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P47801-1", "protein_name": "Epithelial membrane protein 1", "gene_name": "Emp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLVLLAGLFVVHIATAIMLFVSTIANVWMVADYANASVGLWKNCTGGNCDGSLSYGNEDAIKAVQAFMILSIIFSIISLVVFVFQLFTMEKGNRFFLSGSTMLVCWLCILVGVSIYTHHYAHSEGNFNSSSHQGYCFILTWICFCFSFIIGILYMVLRKK", "length": 160 }, "evidence": [ { "id": "E1BZ46", "url": "https://omabrowser.org/oma/group/E1BZ46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54848-1", "protein_name": "Epithelial membrane protein 1", "gene_name": "Emp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVLLAGLFVVHIATAIMLFVSTIANVWMVADGIDSSIGLWKNCTSGSCDGSLSYGNDDAIKAVQAFMILSIIFSIISLVVFVFQLFTMEKGNRFFLSGSTMLVCWLCILIGVSIYTHHYAHSEGNFFPSSHQGYCFILTWICFCFSFIIGILYMVLRKK", "length": 160 }, "evidence": [ { "id": "E1BZ46", "url": "https://omabrowser.org/oma/group/E1BZ46/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P54849-1", "protein_name": "Epithelial membrane protein 1", "gene_name": "EMP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK", "length": 157 }, "evidence": [ { "id": "E1BZ46", "url": "https://omabrowser.org/oma/group/E1BZ46/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BZ46", "url": "https://www.uniprot.org/uniprotkb/E1BZ46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1BZ46", "url": "https://www.uniprot.org/uniprotkb/E1BZ46" } ], "pmid": "" }, { "name": "bleb assembly", "id": "GO:0032060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032060", "evidence": [ { "database": "UniProtKB", "id": "E1BZ46", "url": "https://www.uniprot.org/uniprotkb/E1BZ46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BZ46-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 165, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BZ46-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BZ46" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BZ77-1", "uniprot_ac": "E1BZ77", "uniprot_id": "E1BZ77_CHICK", "mass": { "chemical_mass": 85946.0, "monoisotopic_mass": 85946.0 }, "refseq": { "ac": "XP_418005", "name": "protein PHTF1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418005" }, "gene_names": [ { "name": "PHTF1", "type": "recommended", "evidence": [ { "id": "E1BZ77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ77" } ] }, { "name": "PHTF1", "type": "synonym", "evidence": [ { "id": "XP_418005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418005" } ] } ], "protein_names": [ { "name": "Putative homeodomain transcription factor 1", "type": "synonym", "evidence": [ { "id": "E1BZ77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ77/entry#names_and_taxonomy" } ] }, { "name": "protein PHTF1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_418005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418005" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052557.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418005.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418005" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZ77", "url": "https://www.uniprot.org/uniprotkb/E1BZ77" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHTF1", "url": "https://www.uniprot.org/uniprotkb/E1BZ77", "locus": { "chromosome": "26", "start_pos": 3759812, "end_pos": 3770846, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027256", "url": "https://www.ensembl.org/id/ENSGALG00010027256" } ] } } ], "crossref": [ { "id": "E1BZ77", "url": "https://alphafold.ebi.ac.uk/entry/E1BZ77", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001845", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001845", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419878", "url": "https://www.ncbi.nlm.nih.gov/gene/419878", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1BZ77", "url": "https://www.orthodb.org/?gene=E1BZ77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12680:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12680:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BZ77", "url": "https://www.uniprot.org/uniprotkb/E1BZ77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ77-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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CANONICAL=E1BZ77-1" }, "locus": { "chromosome": "26", "start_pos": 3770795, "end_pos": 3761150, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066081.1", "url": "https://www.ensembl.org/id/ENSGALT00010066081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040347.1", "url": "https://www.ensembl.org/id/ENSGALP00010040347.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1BZ77", "url": "https://www.uniprot.org/uniprotkb/E1BZ77" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BZ77", "url": "https://www.uniprot.org/uniprotkb/E1BZ77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BZ77-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 752, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BZ77-F1.pdb", "url_external": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BZ94-1", "uniprot_ac": "E1BZ94", "uniprot_id": "E1BZ94_CHICK", "mass": { "chemical_mass": 20303.0, "monoisotopic_mass": 20303.0 }, "refseq": { "ac": "XP_419716", "name": "coiled-coil domain-containing protein 28A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419716" }, "gene_names": [ { "name": "CCDC28A", "type": "recommended", "evidence": [ { "id": "E1BZ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ94" } ] }, { "name": "CCDC28A", "type": "synonym", "evidence": [ { "id": "XP_419716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419716" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 28A", "type": "synonym", "evidence": [ { "id": "E1BZ94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ94/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 28A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419716" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419716" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZ94", "url": "https://www.uniprot.org/uniprotkb/E1BZ94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC28A", "url": "https://www.uniprot.org/uniprotkb/E1BZ94", "locus": { "chromosome": "3", "start_pos": 53868061, "end_pos": 53876594, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004217", "url": "https://www.ensembl.org/id/ENSGALG00010004217" } ] } } ], "crossref": [ { "id": "E1BZ94", "url": "https://alphafold.ebi.ac.uk/entry/E1BZ94", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013834", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013834", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421679", "url": "https://www.ncbi.nlm.nih.gov/gene/421679", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421679", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421679", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKSSMTH", "url": "https://omabrowser.org/oma/group/PKSSMTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGB0", "url": "https://www.orthodb.org/?gene=A0A8V0XGB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZ94", "url": "https://www.orthodb.org/?gene=E1BZ94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13400", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13400", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13400:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13400:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XGB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ94", "url": "https://www.uniprot.org/uniprotkb/E1BZ94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZ94-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEERKIKRRSPKSSTAHPVQVANSKKSSVPVSKSTAFSNPAPQPPGQKPKLKRVIKEKAKPPGGEAKGAQAAPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRSMQEKLARLNLELYGELEELPEDKRKLASDSNLDRLLSDLEELNSSIQKLHLADAQDIPNSTTG", "length": 184, "header": "tr|E1BZ94-1|E1BZ94_CHICK Isoform 1 of Coiled-coil domain containing 28A OS=Gallus gallus OX=9031 GN=CCDC28A PE=4 SV=1 CANONICAL=E1BZ94-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XGB0-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ94/entry#A0A8V0XGB0-1", "sequence": { "sequence": "MEERKIKRRSPKSSTAHPVQVANSKKSSVPVSKSTAFSNPAPQPPGQKPKLKRVIKEKAKPPGGEAKGAQAAPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRSMQEKLARLNLELYGELEELPEDKRKLASDSNLDRLLSDQMLKIFQIAPRAEETAFSVWVLT", "length": 182, "header": "tr|A0A8V0XGB0-1|A0A8V0XGB0_CHICK Computationally mapped isoform of Coiled-coil domain containing 28A OS=Gallus gallus OX=9031 GN=CCDC28A PE=4 SV=1 CANONICAL=E1BZ94-1" }, "locus": { "chromosome": "3", "start_pos": 53876028, "end_pos": 53871721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009849.1", "url": "https://www.ensembl.org/id/ENSGALT00010009849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005745.1", "url": "https://www.ensembl.org/id/ENSGALP00010005745.1" } ] } }, { "isoform_ac": "E1BZ94-1", "url": "https://www.uniprot.org/uniprotkb/E1BZ94/entry#E1BZ94-1", "sequence": { "sequence": "MEERKIKRRSPKSSTAHPVQVANSKKSSVPVSKSTAFSNPAPQPPGQKPKLKRVIKEKAKPPGGEAKGAQAAPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRSMQEKLARLNLELYGELEELPEDKRKLASDSNLDRLLSDLEELNSSIQKLHLADAQDIPNSTTG", "length": 184, "header": "tr|E1BZ94-1|E1BZ94_CHICK Isoform 1 of Coiled-coil domain containing 28A OS=Gallus gallus OX=9031 GN=CCDC28A PE=4 SV=1 CANONICAL=E1BZ94-1" }, "locus": { "chromosome": "3", "start_pos": 53876028, "end_pos": 53871755, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009850.1", "url": "https://www.ensembl.org/id/ENSGALT00010009850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005746.1", "url": "https://www.ensembl.org/id/ENSGALP00010005746.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421679", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421679", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MIV4-1", "protein_name": "Coiled-coil domain-containing protein 28A isoform X1", "gene_name": "Ccdc28a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEERKAKRKSPKSFSAHSTQVANAKKNAIPASKSTGFSNPAAQSTSQRPKLKRVMKEKNKPPGGEGKGAQTTPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKAASDANLDRLLSDGAEKLTQRLKVLAALAEDPDSVPSTHMAALNRL", "length": 192 }, "evidence": [ { "id": "E1BZ94", "url": "https://omabrowser.org/oma/group/E1BZ94/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MJ64-1", "protein_name": "Coiled-coil domain containing 28A", "gene_name": "CCDC28A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEERKVKRRSPKSFSAHSTQVVNTKKNAIPVSKSTGFSNPASQSTSQRPKLKRVTKEKARPPGGEGRGAQAAPIQHSFLTDVSDVQEMERGLLSLLNDFHSGKLQAFGNECSIEQMEHVRGMQEKLARLNLELYGELEELPEDKRKAASDSNLERLLSDLEELNSSIQKLHLADAQDVPNTSTS", "length": 184 }, "evidence": [ { "id": "E1BZ94", "url": "https://omabrowser.org/oma/group/E1BZ94/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"E1BZD9_CHICK", "mass": { "chemical_mass": 35484.0, "monoisotopic_mass": 35484.0 }, "refseq": { "ac": "XP_015134112", "name": "transmembrane protein 255A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134112" }, "gene_names": [ { "name": "TMEM255A", "type": "recommended", "evidence": [ { "id": "E1BZD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZD9" } ] }, { "name": "TMEM255A", "type": "synonym", "evidence": [ { "id": "XP_015134112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134112" } ] } ], "protein_names": [ { "name": "Transmembrane protein 255A", "type": "recommended", "evidence": [ { "id": "E1BZD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZD9/entry#names_and_taxonomy" } ] }, { "name": "Protein FAM70A", "type": "synonym", "evidence": [ { "id": "E1BZD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZD9/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 255A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134112" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZD9", "url": "https://www.uniprot.org/uniprotkb/E1BZD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM255A", "url": "https://www.uniprot.org/uniprotkb/E1BZD9", "locus": { "chromosome": "4", "start_pos": 16430921, "end_pos": 16406698, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016370", "url": "https://www.ensembl.org/id/ENSGALG00010016370" } ] } } ], "crossref": [ { "id": "E1BZD9", "url": "https://alphafold.ebi.ac.uk/entry/E1BZD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008604", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008604", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107052097", "url": "https://www.ncbi.nlm.nih.gov/gene/107052097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107052097", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MWASNAP", "url": "https://omabrowser.org/oma/group/MWASNAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BZD9", "url": "https://www.orthodb.org/?gene=E1BZD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33721:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33721:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14967", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14967", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BZD9", "url": "https://www.uniprot.org/uniprotkb/E1BZD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BZD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQSLTQQRPGGIALPDSVGSFNRRKRNSLYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLRPLYAGRCQYYSKSTTPPEAVCHPQRRAPCTPKIKTNTCFCCDLYNCGNRVEISGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAILGGFKDMTPSLPTLNCTVENAHPTVSYYSRPQVTSYNTYYHSTPHLPPYSAYDFQHSSVFPASTPSGLSDDPQSVSPSPSYMWSSNAPPRYSPPYFPPFEKPPPYTP", "length": 323, "header": "tr|E1BZD9-1|E1BZD9_CHICK Isoform 1 of Transmembrane protein 255A OS=Gallus gallus OX=9031 GN=TMEM255A PE=3 SV=3 CANONICAL=E1BZD9-1" }, "isoforms": [ { "isoform_ac": "E1BZD9-1", "url": "https://www.uniprot.org/uniprotkb/E1BZD9/entry#E1BZD9-1", "sequence": { "sequence": "MRQSLTQQRPGGIALPDSVGSFNRRKRNSLYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLRPLYAGRCQYYSKSTTPPEAVCHPQRRAPCTPKIKTNTCFCCDLYNCGNRVEISGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAILGGFKDMTPSLPTLNCTVENAHPTVSYYSRPQVTSYNTYYHSTPHLPPYSAYDFQHSSVFPASTPSGLSDDPQSVSPSPSYMWSSNAPPRYSPPYFPPFEKPPPYTP", "length": 323, "header": "tr|E1BZD9-1|E1BZD9_CHICK Isoform 1 of Transmembrane protein 255A OS=Gallus gallus OX=9031 GN=TMEM255A PE=3 SV=3 CANONICAL=E1BZD9-1" }, "locus": { "chromosome": "4", "start_pos": 16428446, "end_pos": 16406768, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039405.1", "url": "https://www.ensembl.org/id/ENSGALT00010039405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022730.1", "url": "https://www.ensembl.org/id/ENSGALP00010022730.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 58, "start_aa": "Thr", "end_pos": 58, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr58", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107052097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107052097", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LN07-1", "protein_name": "Transmembrane protein 255A", "gene_name": "Tmem255a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHQSLTQQRSSDMSLQDSMGAFNRRKRNSIYVTVTLLIVSMLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLIDNKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVPKTSQREAEEVITSSNKLTPSTRSLKNITQAIKEVNCPQLSRGLCTPRIRGNTCFCCDLYNCGSRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNPTHPTLNCSVENAHPTVSYYARPQVASYNTYYNSPPHLPPYSAYDFQHSSVFPPSPPSGLSDEQEPQSASPSPSYTWSSSAPPRYSPPYYPPFEKPPPYSP", "length": 351 }, "evidence": [ { "id": "E1BZD9", "url": "https://omabrowser.org/oma/group/E1BZD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M9PZT9-1", "protein_name": "Transmembrane protein 255A", "gene_name": "tmem255a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPAGLNAQGSGIPISDPMGSFKRRKRKSIIVTVMLLIVSILILVFGLAATTRTQNITVGGYYPGVILGFGSFLGIIGAHLIENKRQMLVASIVFISFGVVAAFCCAIVDGVFAARHIDLRPLYGGRCEYYSSGTAFDVDVHCQTGSRVSCNLRVKSNTCYCCELYNCGKYVCVSMSHSDTSLLGYLLQAARSDFFKKYIATTKLSLFYLGLYLLVWCMLQSLKFSSVRKNVCVYLCFREHPLMGLQNKDVLKKFRKSSMIWNRVELRGGYHEYTEVRSCQDVVHLYHLLWSATILNIVALFLGIITAAVLGGFKDMMPTAAPDSCEPEPLPIPPPPETPGPTTSNNSFYNTAPCLPPYTAYDLQGASFFPDSSGLSDDSQSGASHMWPNMIPPRYSPPYYPPDEKPPPYSP", "length": 411 }, "evidence": [ { "id": "E1BZD9", "url": "https://omabrowser.org/oma/group/E1BZD9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "K7GNE2-1", "protein_name": "Transmembrane protein 255A", "gene_name": "TMEM255A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHQSLTQQRSSDMSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLVENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVPKTSQKEAEEVNCPHLSRGFCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNPTLPALNCSVENAHPTVAYYARPQVASYNTYYHSPPHLPPYSAYDFQHSSIFPSSPPSGLSDEPQSASPSPSYMWSSSAPPRYSPPYYPPFEKPPPYSP", "length": 325 }, "evidence": [ { "id": "E1BZD9", "url": "https://omabrowser.org/oma/group/E1BZD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5JRV8-1", "protein_name": "Transmembrane protein 255A", "gene_name": "TMEM255A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHQSLTQQRSSDMSLPDSMGAFNRRKRNSIYVTVTLLIVSVLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVPKTSQKEAEEVISSSTKNSPSTRVMRNLTQAAREVNCPHLSREFCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNPTLPALNCSVENTHPTVSYYAHPQVASYNTYYHSPPHLPPYSAYDFQHSGVFPSSPPSGLSDEPQSASPSPSYMWSSSAPPRYSPPYYPPFEKPPPYSP", "length": 349 }, "evidence": [ { "id": "E1BZD9", "url": "https://omabrowser.org/oma/group/E1BZD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMP6-1", "protein_name": "Transmembrane protein 255A", "gene_name": "Tmem255a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BZI3-1", "uniprot_ac": "E1BZI3", "uniprot_id": "E1BZI3_CHICK", "mass": { "chemical_mass": 22010.0, "monoisotopic_mass": 22010.0 }, "refseq": { "ac": "NP_001264547", "name": "C-type lectin domain family 3 member A precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264547" }, "gene_names": [ { "name": "CLEC3A", "type": "recommended", "evidence": [ { "id": "E1BZI3", "database": "UniProtKB", "url": 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sample supports all introns SAMEA103992437, SAMEA103992559 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000248.1. On Apr 12, 2013 this sequence version replaced XP_423644.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the transcript data. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264547" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZI3", "url": "https://www.uniprot.org/uniprotkb/E1BZI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLEC3A", "url": "https://www.uniprot.org/uniprotkb/E1BZI3", "locus": { "chromosome": "11", "start_pos": 13689941, "end_pos": 13682987, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007772", "url": "https://www.ensembl.org/id/ENSGALG00010007772" } ] } } ], "crossref": [ { "id": "E1BZI3", "url": "https://alphafold.ebi.ac.uk/entry/E1BZI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013223", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013223", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03596", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03596", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425961", "url": "https://www.ncbi.nlm.nih.gov/gene/425961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425961", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYICEFL", "url": "https://omabrowser.org/oma/group/RYICEFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BZI3", "url": "https://www.orthodb.org/?gene=E1BZI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264547", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264547", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BZI3", "url": "https://www.uniprot.org/uniprotkb/E1BZI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZI3-1", "url": "https://www.uniprot.org/uniprotkb/E1BZI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQTGLMIFLLISILLLDQTISQASKFKAKKHSKRRVKDKDDLKTQIDKLWREVNALKEMQALQSVCLRGTKAHKKCYLISEGTKHFHEANEDCIAKGGTLAIPRNSDEMNTLRDYGKNSVPGGSEFWLGVNDMVNEGKFVDVNGMALQYFNWDRAQPNGGKRENCVFFSTQGKWVDEICRTAKRYICEFLIP", "length": 193, "header": "tr|E1BZI3-1|E1BZI3_CHICK Isoform 1 of C-type lectin domain family 3 member A OS=Gallus gallus OX=9031 GN=CLEC3A PE=4 SV=1 CANONICAL=E1BZI3-1" }, "isoforms": [ { "isoform_ac": "E1BZI3-1", "url": "https://www.uniprot.org/uniprotkb/E1BZI3/entry#E1BZI3-1", "sequence": { "sequence": "MAQTGLMIFLLISILLLDQTISQASKFKAKKHSKRRVKDKDDLKTQIDKLWREVNALKEMQALQSVCLRGTKAHKKCYLISEGTKHFHEANEDCIAKGGTLAIPRNSDEMNTLRDYGKNSVPGGSEFWLGVNDMVNEGKFVDVNGMALQYFNWDRAQPNGGKRENCVFFSTQGKWVDEICRTAKRYICEFLIP", "length": 193, "header": "tr|E1BZI3-1|E1BZI3_CHICK Isoform 1 of C-type lectin domain family 3 member A OS=Gallus gallus OX=9031 GN=CLEC3A PE=4 SV=1 CANONICAL=E1BZI3-1" }, "locus": { "chromosome": "11", "start_pos": 13688769, "end_pos": 13683081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018476.1", "url": "https://www.ensembl.org/id/ENSGALT00010018476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010113.1", "url": "https://www.ensembl.org/id/ENSGALP00010010113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425961", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425961", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q4Q2-1", "protein_name": "C-type lectin domain family 3 member A", "gene_name": "clec3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRQFLLLLLVFCFSFIQDGYGHPSRTKKAVPARQREEDDMKTQIDKLWQEVNSLKEMQALQTVCLRGIKAHRKCYLVSDQAKHYHEANEDCISQGGTLAIPRDVNENEELRDYAKRSSPAARDFWIGITDIVREGQYVDVNSLPVSFFYWDRAKKEPTGGKRESCVALSLSAQGKWHDEVCRSQKKYICEYLIP", "length": 194 }, "evidence": [ { "id": "E1BZI3", "url": "https://omabrowser.org/oma/group/E1BZI3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3L7I0A6-1", "protein_name": "C-type lectin domain family 3 member A", "gene_name": "Clec3a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKNGLVICILVASLLLDQTNSYPSRVKARKHSKRRVKEKDGDLKSQVEKLWREVNALKEMQALQTVCLRGTKVHKKCYLASEGLKHYHEANEDCISKGGTLVVPRNSDEINVLRDYSKKSLPGVNDFWLGINDMVTEGKFLDVHGFAVSFLNWDRAQPSGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFIIP", "length": 196 }, "evidence": [ { "id": "E1BZI3", "url": "https://omabrowser.org/oma/group/E1BZI3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A0E3-1", "protein_name": "C-type lectin domain family 3, member A", "gene_name": "Clec3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKNRLVICILVASLLLDQISSYPSRAKARKHSKRRVKEKDGDLKSQVEKLWREVNALKEMQALQTVCLRGTKVHKKCYLASEGLKHYHEANEDCISKGGTLVVPRNSDEINALRDYSKRSLPGVNDFWLGINDMVTEGKFLDVHGFAVSFLNWDRAQPSGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFIIP", "length": 196 }, "evidence": [ { "id": "E1BZI3", "url": "https://omabrowser.org/oma/group/E1BZI3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75596-1", "protein_name": "C-type lectin domain family 3 member A", "gene_name": "CLEC3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKNGLVICILVITLLLDQTTSHTSRLKARKHSKRRVRDKDGDLKTQIEKLWTEVNALKEIQALQTVCLRGTKVHKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLPGVNDFWLGINDMVTEGKFVDVNGIAISFLNWDRAQPNGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFTIPQ", "length": 197 }, "evidence": [ { "id": "E1BZI3", "url": "https://omabrowser.org/oma/group/E1BZI3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q28008-1", "protein_name": "C-type lectin domain family 3 member A", "gene_name": "CLEC3A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKNGLVIYILVITLLLDQTSCHASKFKARKHSKRRVKEKDGDLKTQVEKLWREVNALKEMQALQTVCLRGTKFHKKCYLAAEGLKHFHEANEDCISKGGTLVVPRSADEINALRDYGKRSLPGVNDFWLGINDMVAEGKFVDINGLAISFLNWDQAQPNGGKRENCALFSQSAQGKWSDEACHSSKRYICEFTIPQ", "length": 197 }, "evidence": [ { "id": "E1BZI3", "url": "https://omabrowser.org/oma/group/E1BZI3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9EPW4-1", "protein_name": "C-type lectin domain family 3 member A", "gene_name": "Clec3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKNGLVLCILVVSLLLDQTDGYPSRMKARKHSKRRVKAKDDDLKSQVEKLWREVNALKEMQALQTVCLRGTKVHKKCYLASEGLKHYHEANEDCISKGGTLVVPRNSDEINALRDYGKRSLPGVNDFWLGINDMVTEGKFLDVHGFAVSFLNWDRAQPSGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFIIP", "length": 196 }, "evidence": [ { "id": "E1BZI3", "url": "https://omabrowser.org/oma/group/E1BZI3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1BZI3", "url": "https://www.uniprot.org/uniprotkb/E1BZI3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E1BZI3", "url": "https://www.uniprot.org/uniprotkb/E1BZI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "E1BZI3", "url": "https://www.uniprot.org/uniprotkb/E1BZI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BZI3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 193, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BZI3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BZI3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQS0-1", "uniprot_ac": "E1BQS0", "uniprot_id": "E1BQS0_CHICK", "mass": { "chemical_mass": 52569.0, "monoisotopic_mass": 52569.0 }, "refseq": { "ac": "XP_015142718", "name": "autophagy-related protein 13 isoform X10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142718" }, "gene_names": [ { "name": "ATG13", "type": "recommended", "evidence": [ { "id": "E1BQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ] }, { "name": "ATG13", "type": "synonym", "evidence": [ { "id": "XP_015142718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142718" } ] } ], "protein_names": [ { "name": "Autophagy-related protein 13", "type": "recommended", "evidence": [ { "id": "E1BQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#names_and_taxonomy" } ] }, { "name": "autophagy-related protein 13 isoform X10", "type": "synonym", "evidence": [ { "id": "XP_015142718", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142718" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142718" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ATG13", "url": "https://www.uniprot.org/uniprotkb/E1BQS0", "locus": { "chromosome": "5", "start_pos": 23014062, "end_pos": 23043047, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023064", "url": "https://www.ensembl.org/id/ENSGALG00010023064" } ] } } ], "crossref": [ { "id": "E1BQS0", "url": "https://alphafold.ebi.ac.uk/entry/E1BQS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008347", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008347", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423192", "url": "https://www.ncbi.nlm.nih.gov/gene/423192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U2X5", "url": "https://www.orthodb.org/?gene=A0A3Q2U2X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR64", "url": "https://www.orthodb.org/?gene=A0A8V0ZR64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR89", "url": "https://www.orthodb.org/?gene=A0A8V0ZR89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT69", "url": "https://www.orthodb.org/?gene=A0A8V0ZT69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU38", "url": "https://www.orthodb.org/?gene=A0A8V0ZU38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU68", "url": "https://www.orthodb.org/?gene=A0A8V0ZU68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU93", "url": "https://www.orthodb.org/?gene=A0A8V0ZU93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQS0", "url": "https://www.orthodb.org/?gene=E1BQS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13430:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13430:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1632852", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015142718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2X5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQS0-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMVNPPDSPETESPLQGSLHSEGSSGSSAGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 479, "header": "tr|E1BQS0-1|E1BQS0_CHICK Isoform 1 of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=3 CANONICAL=E1BQS0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U2X5-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#A0A3Q2U2X5-1", "sequence": { "sequence": "MDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQLSSSRLSYQPAALGVGSADMGYPVLFAGGLNAAHPHQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMVNPPDSPETESPLQGSLHSEGSSGSSAGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 516, "header": "tr|A0A3Q2U2X5-1|A0A3Q2U2X5_CHICK Computationally mapped isoform of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=1 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23030730, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056203.1", "url": "https://www.ensembl.org/id/ENSGALT00010056203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034020.1", "url": "https://www.ensembl.org/id/ENSGALP00010034020.1" } ] } }, { "isoform_ac": "A0A8V0ZR64-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#A0A8V0ZR64-1", "sequence": { "sequence": "MDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQCVFTVTKAHFQTPPPVVTDTLKVPVMGLAFSHQLSSSRLSYQPAALGVGSADMGYPVLFAGGLNAAHPHQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVNPPDSPETESPLQGSLHSEGSSGSSAGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 523, "header": "tr|A0A8V0ZR64-1|A0A8V0ZR64_CHICK Computationally mapped isoform of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=1 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23030730, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056183.1", "url": "https://www.ensembl.org/id/ENSGALT00010056183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034001.1", "url": "https://www.ensembl.org/id/ENSGALP00010034001.1" } ] } }, { "isoform_ac": "A0A8V0ZR89-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#A0A8V0ZR89-1", "sequence": { "sequence": "MLRYLTAGLPYAMDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMVNPPDSPETESPLQGSLHSEGSSGSSAGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 491, "header": "tr|A0A8V0ZR89-1|A0A8V0ZR89_CHICK Computationally mapped isoform of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=1 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23033649, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056211.1", "url": "https://www.ensembl.org/id/ENSGALT00010056211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034026.1", "url": "https://www.ensembl.org/id/ENSGALP00010034026.1" } ] } }, { "isoform_ac": "A0A8V0ZT69-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#A0A8V0ZT69-1", "sequence": { "sequence": "MDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQLSSSRLSYQPAALGVGSADMGYPVLFAGGLNAAHPHQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 477, "header": "tr|A0A8V0ZT69-1|A0A8V0ZT69_CHICK Computationally mapped isoform of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=1 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23030730, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056206.1", "url": "https://www.ensembl.org/id/ENSGALT00010056206.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034023.1", "url": "https://www.ensembl.org/id/ENSGALP00010034023.1" } ] } }, { "isoform_ac": "A0A8V0ZU38-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#A0A8V0ZU38-1", "sequence": { "sequence": "MDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQCVFTVTKAHFQTPPPVVTDTLKVPVMGLAFSHQLSSSRLSYQPAALGVGSADMGYPVLFAGGLNAAHPHQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 510, "header": "tr|A0A8V0ZU38-1|A0A8V0ZU38_CHICK Computationally mapped isoform of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=1 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23030730, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056168.1", "url": "https://www.ensembl.org/id/ENSGALT00010056168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033987.1", "url": "https://www.ensembl.org/id/ENSGALP00010033987.1" } ] } }, { "isoform_ac": "A0A8V0ZU68-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#A0A8V0ZU68-1", "sequence": { "sequence": "MDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQCVFTVTKAHFQTPPPVVTDTLKVPVMGLAFSHQLSSSRLSYQPAALGVGSADMGYPVLFAGGLNAAHPHQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMVNPPDSPETESPLQGSLHSEGSSGSSAGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 516, "header": "tr|A0A8V0ZU68-1|A0A8V0ZU68_CHICK Computationally mapped isoform of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=1 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23030730, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056194.1", "url": "https://www.ensembl.org/id/ENSGALT00010056194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034012.1", "url": "https://www.ensembl.org/id/ENSGALP00010034012.1" } ] } }, { "isoform_ac": "A0A8V0ZU93-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#A0A8V0ZU93-1", "sequence": { "sequence": "MVKMRREVAKKRLPYAMDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQCVFTVTKAHFQTPPPVVTDTLKVPVMGLAFSHQLSSSRLSYQPAALGVGSADMGYPVLFAGGLNAAHPHQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMVNPPDSPETESPLQGSLHSEGSSGSSAGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 565, "header": "tr|A0A8V0ZU93-1|A0A8V0ZU93_CHICK Computationally mapped isoform of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=1 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23042921, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056220.1", "url": "https://www.ensembl.org/id/ENSGALT00010056220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034032.1", "url": "https://www.ensembl.org/id/ENSGALP00010034032.1" } ] } }, { "isoform_ac": "E1BQS0-1", "url": "https://www.uniprot.org/uniprotkb/E1BQS0/entry#E1BQS0-1", "sequence": { "sequence": "MDTDLSSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYTVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRAGEDNGAVYPSVEDSQEVCTTSFSTSPPSQLIGPGKEGGVPPVPSQPAHGTQADQERMCTPLDGVHYSAATPSSSEDTETVSNSSEGKCGSPHDLLETIFIRKVGAFVNKPINQVTMANLDIPFAMFAPKNVELEDNDPMVNPPDSPETESPLQGSLHSEGSSGSSAGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVKEFDAFVETLQ", "length": 479, "header": "tr|E1BQS0-1|E1BQS0_CHICK Isoform 1 of Autophagy-related protein 13 OS=Gallus gallus OX=9031 GN=ATG13 PE=3 SV=3 CANONICAL=E1BQS0-1" }, "locus": { "chromosome": "5", "start_pos": 23030730, "end_pos": 23017040, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056216.1", "url": "https://www.ensembl.org/id/ENSGALT00010056216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034029.1", "url": "https://www.ensembl.org/id/ENSGALP00010034029.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1632852", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1632852", "resource": "Reactome", "description": "Macroautophagy" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "protein localization to phagophore assembly site", "id": "GO:0034497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034497", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "response to mitochondrial depolarisation", "id": "GO:0098780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098780", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "Atg1/ULK1 kinase complex", "id": "GO:1990316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990316", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "phagophore assembly site membrane", "id": "GO:0034045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034045", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "kinase activator activity", "id": "GO:0019209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019209", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" }, { "name": "protein kinase regulator activity", "id": "GO:0019887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019887", "evidence": [ { "database": "UniProtKB", "id": "E1BQS0", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQS0" }, { "id": "PF10033", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Autophagy-related protein 13 N-terminal", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 195, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 135, 303 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 315, "end_pos": 317 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXU3-1", "uniprot_ac": "E1BXU3", "uniprot_id": "E1BXU3_CHICK", "mass": { "chemical_mass": 24476.0, "monoisotopic_mass": 24476.0 }, "refseq": { "ac": "XP_004935173", "name": "ropporin-1-like protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935173" }, "gene_names": [ { "name": "ROPN1L", "type": "recommended", "evidence": [ { "id": "E1BXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ] }, { "name": "ROPN1L", "type": "synonym", "evidence": [ { "id": "XP_004935173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935173" } ] } ], "protein_names": [ { "name": "Ropporin-1-like protein", "type": "recommended", "evidence": [ { "id": "E1BXU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXU3/entry#names_and_taxonomy" } ] }, { "name": "ropporin-1-like protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004935173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935173" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_004935173.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935173" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ROPN1L", "url": "https://www.uniprot.org/uniprotkb/E1BXU3", "locus": { "chromosome": "2", "start_pos": 77918296, "end_pos": 77929197, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000789", "url": "https://www.ensembl.org/id/ENSGALG00010000789" } ] } } ], "crossref": [ { "id": "E1BXU3", "url": "https://alphafold.ebi.ac.uk/entry/E1BXU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013006", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013006", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23019", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23019", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420926", "url": "https://www.ncbi.nlm.nih.gov/gene/420926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR047844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420926", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWSSAYF", "url": "https://omabrowser.org/oma/group/QWSSAYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X0Y4", "url": "https://www.orthodb.org/?gene=A0A8V0X0Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X3U1", "url": "https://www.orthodb.org/?gene=A0A8V0X3U1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X6B1", "url": "https://www.orthodb.org/?gene=A0A8V0X6B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X8R1", "url": "https://www.orthodb.org/?gene=A0A8V0X8R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXU3", "url": "https://www.orthodb.org/?gene=E1BXU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14952:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14952:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_004935173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X0Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X0Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X0Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X0Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3U1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X3U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3U1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X6B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X6B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BXU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLPDTLFCAQQIKIPPELPDIMKQFTKAAIRTQPRDVLQWSAAYFTALSKGELLPVKERIETPSAKQKMDAGLTPGLLKVLHKQLSAKGTVSVAELKKKWKDLCLPEEQLEAILQLDIFDEEVEWMKILALGCSMLGESLLSSMKHACEILTQDPEGGAARIPYETFSFLYCYLASIDGDIPDEKIKAFLQKIKDDADRQSGMVLLRNFQSQPSTQF", "length": 218, "header": "tr|E1BXU3-1|E1BXU3_CHICK Isoform 1 of Ropporin-1-like protein OS=Gallus gallus OX=9031 GN=ROPN1L PE=3 SV=2 CANONICAL=E1BXU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X0Y4-1", "url": "https://www.uniprot.org/uniprotkb/E1BXU3/entry#A0A8V0X0Y4-1", "sequence": { "sequence": "MPLPDTLFCAQQIKIPPELPDIMKQFTKAAIRTQPRDVLQWSAAYFTALSKGELLPVKERIETPSAKQKMDAGLTPGLLKVLHKQLSAKGTVSVAELKKKWKDLCLPEEQLEAILQLDIFDEEVEWMKILALGCSMLGEDPEGGAARIPYETFSFLYCYLASIDGDIPDEKIKAFLQKIKDDADRQSGMVLLRNFQSQPSTQF", "length": 203, "header": "tr|A0A8V0X0Y4-1|A0A8V0X0Y4_CHICK Computationally mapped isoform of Ropporin-1-like protein OS=Gallus gallus OX=9031 GN=ROPN1L PE=3 SV=1 CANONICAL=E1BXU3-1" }, "locus": { "chromosome": "2", "start_pos": 77926462, "end_pos": 77920484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001726.1", "url": "https://www.ensembl.org/id/ENSGALT00010001726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000927.1", "url": "https://www.ensembl.org/id/ENSGALP00010000927.1" } ] } }, { "isoform_ac": "A0A8V0X3U1-1", "url": "https://www.uniprot.org/uniprotkb/E1BXU3/entry#A0A8V0X3U1-1", "sequence": { "sequence": "MVHVTELEKTMPLPDTLFCAQQIKIPPELPDIMKQFTKAAIRTQPRDVLQWSAAYFTALSKGELLPVKERIETPSAKQKMDAGLTPGLLKVLHKQLSAKGTVSVAELKKKWKDLCLPEEQLEAILQLDIFDEEVEWMKILALGCSMLGESLLSSMKHACEILTQDPEGGAARIPYETFSFLYCYLASIDGDIPDEKIKAFLQKIKDDADRQSGMVLLRNFQSQPSTQF", "length": 228, "header": "tr|A0A8V0X3U1-1|A0A8V0X3U1_CHICK Computationally mapped isoform of Ropporin-1-like protein OS=Gallus gallus OX=9031 GN=ROPN1L PE=3 SV=1 CANONICAL=E1BXU3-1" }, "locus": { "chromosome": "2", "start_pos": 77927694, "end_pos": 77920484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001725.1", "url": "https://www.ensembl.org/id/ENSGALT00010001725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000926.1", "url": "https://www.ensembl.org/id/ENSGALP00010000926.1" } ] } }, { "isoform_ac": "A0A8V0X6B1-1", "url": "https://www.uniprot.org/uniprotkb/E1BXU3/entry#A0A8V0X6B1-1", "sequence": { "sequence": "MLRMRRADIEGCVHVTELEKTMPLPDTLFCAQQIKIPPELPDIMKQFTKAAIRTQPRDVLQWSAAYFTALSKGELLPVKERIETPSAKQKMDAGLTPGLLKVLHKQLSAKGTVSVAELKKKWKDLCLPEEQLEAILQLDIFDEEVEWMKILALGCSMLGESLLSSMKHACEILTQDPEGGAARIPYETFSFLYCYLASIDGDIPDEKIKAFLQKIKDDADRQSGMVLLRNFQSQPSTQF", "length": 239, "header": "tr|A0A8V0X6B1-1|A0A8V0X6B1_CHICK Computationally mapped isoform of Ropporin-1-like protein OS=Gallus gallus OX=9031 GN=ROPN1L PE=3 SV=1 CANONICAL=E1BXU3-1" }, "locus": { "chromosome": "2", "start_pos": 77927228, "end_pos": 77920484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001723.1", "url": "https://www.ensembl.org/id/ENSGALT00010001723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000924.1", "url": "https://www.ensembl.org/id/ENSGALP00010000924.1" } ] } }, { "isoform_ac": "A0A8V0X8R1-1", "url": "https://www.uniprot.org/uniprotkb/E1BXU3/entry#A0A8V0X8R1-1", "sequence": { "sequence": "MPLPDTLFCAQQIKIPPELPDIMKQFTKAAIRTQPRDVLQWSAAYFTALSKGELLPVKERIETPSAKQKMDAGLTPGLLKVLHKQLSAKGTVSVAELKKKWKDLCLPEEQLEAILQLDIFDEEVEWMKILALGCSMLGESLLSSMKHACEILTQDPEGGAARIPYETFSFLYCYLASIDGDIPDEKIKAFLQKIKDDA", "length": 198, "header": "tr|A0A8V0X8R1-1|A0A8V0X8R1_CHICK Computationally mapped isoform of Ropporin-1-like protein OS=Gallus gallus OX=9031 GN=ROPN1L PE=3 SV=1 CANONICAL=E1BXU3-1" }, "locus": { "chromosome": "2", "start_pos": 77926462, "end_pos": 77922157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001724.1", "url": "https://www.ensembl.org/id/ENSGALT00010001724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000925.1", "url": "https://www.ensembl.org/id/ENSGALP00010000925.1" } ] } }, { "isoform_ac": "E1BXU3-1", "url": "https://www.uniprot.org/uniprotkb/E1BXU3/entry#E1BXU3-1", "sequence": { "sequence": "MPLPDTLFCAQQIKIPPELPDIMKQFTKAAIRTQPRDVLQWSAAYFTALSKGELLPVKERIETPSAKQKMDAGLTPGLLKVLHKQLSAKGTVSVAELKKKWKDLCLPEEQLEAILQLDIFDEEVEWMKILALGCSMLGESLLSSMKHACEILTQDPEGGAARIPYETFSFLYCYLASIDGDIPDEKIKAFLQKIKDDADRQSGMVLLRNFQSQPSTQF", "length": 218, "header": "tr|E1BXU3-1|E1BXU3_CHICK Isoform 1 of Ropporin-1-like protein OS=Gallus gallus OX=9031 GN=ROPN1L PE=3 SV=2 CANONICAL=E1BXU3-1" }, "locus": { "chromosome": "2", "start_pos": 77926462, "end_pos": 77920484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010001727.1", "url": "https://www.ensembl.org/id/ENSGALT00010001727.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000928.1", "url": "https://www.ensembl.org/id/ENSGALP00010000928.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420926", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0B7-1", "protein_name": "Ropporin-1-like protein", "gene_name": "Ropn1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELADLEKKWKNLCLPVEKFRAIVDLDPSEDKMEWIKFLALGCSSLGGTLNTAMKNVCEILTSDPEGGPARIPFETFAYIYQYLSALDPEFSAVETETYLANLRDTSESRKNGMIGLSDFVIGKKPV", "length": 218 }, "evidence": [ { "id": "E1BXU3", "url": "https://omabrowser.org/oma/group/E1BXU3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1MDV9-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ROPN1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPMATQKTDTGLTQGLLKVLHKQCSHKEYVDLADLEQKWKNLCLPVEKFRALLQLDPCEDKIEWIKFLALGCSMLGGSLNTAMKHLCEILTTDPEGGPARIPFGTFSYVYRYLSGLDSDIPESDTEAYLSSLKENARPIGPLTGGKEHTPSPQPRGVRCGLVV", "length": 225 }, "evidence": [ { "id": "E1BXU3", "url": "https://omabrowser.org/oma/group/E1BXU3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2QC06-1", "protein_name": "Ropporin-1-like protein", "gene_name": "Ropn1l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPVDVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELKDLEKKWKNLCLPIEKFRAILELDPCDEKIEWIKFLALGCSSLGGSLKAAMKNVCEILTEDPEGGPARIPFDTFSYIYQYLSGLDPDHPPGERELFLATLREKSESRKNNMIGLSDFYLGKKT", "length": 217 }, "evidence": [ { "id": "E1BXU3", "url": "https://omabrowser.org/oma/group/E1BXU3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LDE6-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ROPN1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPMATQKTDTGLTQGLLKVLHKQCSHKEYVELADLEQKWKNLCLPIEKFKVLLQLDPCENKIEWIKFLALGCSMLGGSLNTAMKHLCEILTSDPEGGPARIPFEIFSYVYRYLSGLDKEIPASDTESYLSSLKDKVDSRKNGMVGLSDFFTLKKKI", "length": 218 }, "evidence": [ { "id": "E1BXU3", "url": "https://omabrowser.org/oma/group/E1BXU3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66IC9-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ropn1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLSETMYCAQQINIPPALPNMLKQFTKAAIRTQPRDVLQWAADYFSALSKGQDLPVKKRLELPVATQKTDTGLTPGLLKILHQQLTSKETVTKDELLPKWKALHLPVEQLDTILALGNFSENINWMQFFALACSALGGSITSALKHACEILTEDPEGGPAQIPFHMFRSLYTYLAHLDGEIPEEQIDSFLHSLEGQAQSQGGMVQPSNFTSLHTAEK", "length": 218 }, "evidence": [ { "id": "E1BXU3", "url": "https://omabrowser.org/oma/group/E1BXU3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96C74-1", "protein_name": "Ropporin-1-like protein", "gene_name": "ROPN1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLRWSAGYFSALSRGDPLPVKDRMEMPTATQKTDTGLTQGLLKVLHKQCHHKRYVELTDLEQKWKNLCLPKEKFKALLQLDPCENKIKWINFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDSDVSPLETESYLASLKENIDARKNGMIGLSDFFFPKRKLLESIENSEDVGH", "length": 230 }, "evidence": [ { "id": "E1BXU3", "url": "https://omabrowser.org/oma/group/E1BXU3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQ00-1", "protein_name": "Ropporin-1-like protein", "gene_name": "Ropn1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLQWSAGYFSALSRGDPLPVKDRIEMPVATQKTDTGLTQGLLKVLHKQCSHKQYVELADLEKKWKNLCLPVEKLRTILELDPCEDKIEWIKFLALGCSSLGRTLNTAMKNVCEILTSDPEGGPARIPFETFAYVYQYLSGLDPELPAVETENYLTSLRLMSESRKNGMIGLSDFFVGKKII", "length": 218 }, "evidence": [ { "id": "E1BXU3", "url": "https://omabrowser.org/oma/group/E1BXU3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "radial spoke", "id": "GO:0001534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001534", "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "pmid": "" }, { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "E1BXU3", "url": "https://www.uniprot.org/uniprotkb/E1BXU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BTH9-1", "uniprot_ac": "E1BTH9", "uniprot_id": "E1BTH9_CHICK", "mass": { "chemical_mass": 54777.0, "monoisotopic_mass": 54777.0 }, "refseq": { "ac": "NP_001186429", "name": "actin nucleation-promoting factor WASL", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186429" }, "gene_names": [ { "name": "WASL", "type": "recommended", "evidence": [ { "id": "E1BTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ] }, { "name": "WASL", "type": "synonym", "evidence": [ { "id": "NP_001186429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186429" } ] } ], "protein_names": [ { "name": "Actin nucleation-promoting factor WASL", "type": "recommended", "evidence": [ { "id": "E1BTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTH9/entry#names_and_taxonomy" } ] }, { "name": "Neural Wiskott-Aldrich syndrome protein", "type": "synonym", "evidence": [ { "id": "E1BTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTH9/entry#names_and_taxonomy" } ] }, { "name": "actin nucleation-promoting factor WASL", "type": "synonym", "evidence": [ { "id": "NP_001186429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186429" } ] }, { "name": "neural Wiskott-Aldrich syndrome protein", "type": "synonym", "evidence": [ { "id": "NP_001186429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186429" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267658.11341.1, SRR13267656.26244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On May 9, 2013 this sequence version replaced NP_001186429.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186429" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WASL", "url": "https://www.uniprot.org/uniprotkb/E1BTH9", "locus": { "chromosome": "1", "start_pos": 22426924, "end_pos": 22376967, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001686", "url": "https://www.ensembl.org/id/ENSGALG00010001686" } ] } } ], "crossref": [ { "id": "E1BTH9", "url": "https://alphafold.ebi.ac.uk/entry/E1BTH9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008797", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008797", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00132", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00132", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01205", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01205", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22074", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22074", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22075", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22075", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417750", "url": "https://www.ncbi.nlm.nih.gov/gene/417750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417750", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYNQDRK", "url": "https://omabrowser.org/oma/group/EYNQDRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X6F7", "url": "https://www.orthodb.org/?gene=A0A8V0X6F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCI1", "url": "https://www.orthodb.org/?gene=A0A8V0XCI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BTH9", "url": "https://www.orthodb.org/?gene=E1BTH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11202:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11202:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-373753", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373753", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3928662", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928662", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663213", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186429", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X6F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X6F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BTH9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAPQQPPQPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQIYAADRNAMWSKKCCGVACLVKDNPQRSYFIRIYDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVGLNFANEEEAKLFRKTVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYTPQVNNISYTKEKKKGKTKKRRLTKADIGTPSNFQHIGHVGWDPNTGFDVNNLDPELKNLFDLCGISEAQLKDKETSKAIYDFIEKTGGVEAVKNELRRQAPPPPPPCRGGPPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGAAVPPPPPNRMYPPPPPVHSSSAPSGPPPPPPPPASGSSAPPPPPPPPPPPGPPPPPGLPSEVDHQLPVPAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESAPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWDD", "length": 505, "header": "tr|E1BTH9-1|E1BTH9_CHICK Isoform 1 of Actin nucleation-promoting factor WASL OS=Gallus gallus OX=9031 GN=WASL PE=1 SV=4 CANONICAL=E1BTH9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X6F7-1", "url": "https://www.uniprot.org/uniprotkb/E1BTH9/entry#A0A8V0X6F7-1", "sequence": { "sequence": "MSGAPQQPPQPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQIYAADRNAMWSKKCCGVACLVKDNPQRSYFIRIYDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVGLNFANEEEAKLFRKTVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYTPQVNNISYTKEKKKGKTKKRRLTKADIGTPSNFQHIGHVGWDPNTGFDVNNLDPELKNLFDLCGISEAQLKDKETSKAIYDFIEKTGGVEAVKNELRRQGPPRWSAPPPPPPCRGGPPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGAAVPPPPPNRMYPPPPPVHSSSAPSGPPPPPPPPASGSSAPPPPPPPPPPPGPPPPPGLPSEVDHQLPVPAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESAPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWDD", "length": 511, "header": "tr|A0A8V0X6F7-1|A0A8V0X6F7_CHICK Computationally mapped isoform of Actin nucleation-promoting factor WASL OS=Gallus gallus OX=9031 GN=WASL PE=1 SV=1 CANONICAL=E1BTH9-1" }, "locus": { "chromosome": "1", "start_pos": 22424278, "end_pos": 22377280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003868.1", "url": "https://www.ensembl.org/id/ENSGALT00010003868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002172.1", "url": "https://www.ensembl.org/id/ENSGALP00010002172.1" } ] } }, { "isoform_ac": "A0A8V0XCI1-1", "url": "https://www.uniprot.org/uniprotkb/E1BTH9/entry#A0A8V0XCI1-1", "sequence": { "sequence": "MSGAPQQPPQPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQIYAADRNAMWSKKCCGVACLVKDNPQRSYFIRIYDIKTCQVGLNFANEEEAKLFRKTVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYTPQVNNISYTKEKKKGKTKKRRLTKADIGTPSNFQHIGHVGWDPNTGFDVNNLDPELKNLFDLCGISEAQLKDKETSKAIYDFIEKTGGVEAVKNELRRQAPPPPPPCRGGPPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGAAVPPPPPNRMYPPPPPVHSSSAPSGPPPPPPPPASGSSAPPPPPPPPPPPGPPPPPGLPSEVDHQLPVPAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESAPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWDD", "length": 476, "header": "tr|A0A8V0XCI1-1|A0A8V0XCI1_CHICK Computationally mapped isoform of Wiskott-Aldrich syndrome like OS=Gallus gallus OX=9031 GN=WASL PE=1 SV=1 CANONICAL=E1BTH9-1" }, "locus": { "chromosome": "1", "start_pos": 22424278, "end_pos": 22377280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003870.1", "url": "https://www.ensembl.org/id/ENSGALT00010003870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002174.1", "url": "https://www.ensembl.org/id/ENSGALP00010002174.1" } ] } }, { "isoform_ac": "E1BTH9-1", "url": "https://www.uniprot.org/uniprotkb/E1BTH9/entry#E1BTH9-1", "sequence": { "sequence": "MSGAPQQPPQPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQIYAADRNAMWSKKCCGVACLVKDNPQRSYFIRIYDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVGLNFANEEEAKLFRKTVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYTPQVNNISYTKEKKKGKTKKRRLTKADIGTPSNFQHIGHVGWDPNTGFDVNNLDPELKNLFDLCGISEAQLKDKETSKAIYDFIEKTGGVEAVKNELRRQAPPPPPPCRGGPPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGAAVPPPPPNRMYPPPPPVHSSSAPSGPPPPPPPPASGSSAPPPPPPPPPPPGPPPPPGLPSEVDHQLPVPAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESAPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWDD", "length": 505, "header": "tr|E1BTH9-1|E1BTH9_CHICK Isoform 1 of Actin nucleation-promoting factor WASL OS=Gallus gallus OX=9031 GN=WASL PE=1 SV=4 CANONICAL=E1BTH9-1" }, "locus": { "chromosome": "1", "start_pos": 22424278, "end_pos": 22377280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003869.1", "url": "https://www.ensembl.org/id/ENSGALT00010003869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002173.1", "url": "https://www.ensembl.org/id/ENSGALP00010002173.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 460, "start_aa": "Thr", "end_pos": 460, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr460", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 464, "start_aa": "Thr", "end_pos": 464, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr464", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:417750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417750", "resource": "KEGG Pathway" }, { "id": "R-GGA-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-GGA-373753", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-373753", "resource": "Reactome", "description": "Nephrin family interactions" }, { "id": "R-GGA-3928662", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928662", "resource": "Reactome", "description": "EPHB-mediated forward signaling" }, { "id": "R-GGA-5663213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663213", "resource": "Reactome", "description": "RHO GTPases Activate WASPs and WAVEs" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATX4-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSGPQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGVGVPPPPPNRMYPPPPPALPSSAPSGPPPPPPPLSVAGSAAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTPAGSKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED", "length": 505 }, "evidence": [ { "id": "E1BTH9", "url": "https://omabrowser.org/oma/group/E1BTH9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O00401-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED", "length": 505 }, "evidence": [ { "id": "E1BTH9", "url": "https://omabrowser.org/oma/group/E1BTH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O08816-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "Wasl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGQQPPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQLYAADRNCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDAPNGPNLPMATVDIKNPEITTNRFYSSQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGVVVPPPPPNRMYPPPPPALPSSAPSGPPPPPPLSMAGSTAPPPPPPPPPPPGPPPPPGLPSDGDHQVPASSGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDDDDEEDFQDDDEWED", "length": 501 }, "evidence": [ { "id": "E1BTH9", "url": "https://omabrowser.org/oma/group/E1BTH9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12446-1", "protein_name": "Proline-rich protein LAS17", "gene_name": "LAS17", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGLLNSSDKEIIKRALPKASNKIIDVTVARLYIAYPDKNEWQYTGLSGALALVDDLVGNTFFLKLVDINGHRGVIWDQELYVNFEYYQDRTFFHTFEMEECFAGLLFVDINEASHFLKRVQKRERYANRKTLLNKNAVALTKKVREEQKSQVVHGPRGESLIDNQRKRYNYEDVDTIPTTKHKAPPPPPPTAETFDSDQTSSFSDINSTTASAPTTPAPALPPASPEVRKEETHPKHSLPPLPNQFAPLPDPPQHNSPPQNNAPSQPQSNPFPFPIPEIPSTQSATNPFPFPVPQQQFNQAPSMGIPQQNRPLPQLPNRNNRPVPPPPPMRTTTEGSGVRLPAPPPPPRRGPAPPPPPHRHVTSNTLNSAGGNSLLPQATGRRGPAPPPPPRASRPTPNVTMQQNPQQYNNSNRPFGYQTNSNMSSPPPPPVTTFNTLTPQMTAATGQPAVPLPQNTQAPSQATNVPVAPPPPPASLGQSQIPQSAPSAPIPPTLPSTTSAAPPPPPAFLTQQPQSGGAPAPPPPPQMPATSTSGGGSFAETTGDAGRDALLASIRGAGGIGALRKVDKSQLDKPSVLLQEARGESASPPAAAGNGGTPGGPPASLADALAAALNKRKTKVGAHDDMDNGDDW", "length": 633 }, "evidence": [ { "id": "E1BTH9", "url": "https://omabrowser.org/oma/group/E1BTH9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q91YD9-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "Wasl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGQQPPRRVTNVGSLLLTPQENESLFSFLGKKCVTMSSAVVQLYAADRNCMWAKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDAPNGPNLPMATVDIKNPEITTNRFYGSQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGVVVPPPPPNRMYPPPPPALPSSAPSGPPPPPPPSMAGSTAPPPPPPPPPPPGPPPPPGLPSDGDHQVPAPSGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVSDGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDDDDEEDFEDDDEWED", "length": 501 }, "evidence": [ { "id": "E1BTH9", "url": "https://omabrowser.org/oma/group/E1BTH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95107-1", "protein_name": "Actin nucleation-promoting factor WASL", "gene_name": "WASL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSGQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQINNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPGVGAPPPPPNRMYPPPLPALPSSAPSGPPPPPPPLSVSGSVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTPAGSKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVTDAPESTPPAPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDDEDFEDDDEWED", "length": 505 }, "evidence": [ { "id": "E1BTH9", "url": "https://omabrowser.org/oma/group/E1BTH9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VAT0-1", "protein_name": "WASp, isoform B", "gene_name": "WASp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSGMRSQDGPRAKVNAASTLLTQEENEAVFKLLGKKCQTLNTAVVQIYKTEGSAHAHWKKRHTGVVCFVKDSAIRSYFMRAYCLIKNELIWEHEIYDGMEVVKSRPFLLTFEGSDGHVGLNFVSEEECDSFFRIVDATIETRNRKRQEKRNRQKSQQAPNAPLPQVQREPARPPPMQGGLSSTDGVQLRNNKINSVTLTPAPAPAQSKNFLSSSFGLGNNAKDKKRKVTKADISRPTNFVHLSHVGWDAQKGFDLAGNENDEVLNEFFVKAGVSEVELKDRDTRAFIYDFIQSNNVLASVKQYSVESPTETAAPMPPPVPTRHPSNGNQRTAPPLPPARQPPPAVPVTVPGAARAPPPPNRPPPISTAPPPPPVSAPVVAPPPPPPPPPAAVPPPPPPPMPVGEIPVITTTHAPTQAARPAAPAAPDPRNALMDAIRKGTQLKKVDTTALSTGSGDSRSDLMKDIRQGTVLKPAKERELGSQRNSDSGAGTDALADALRRALAARGNAIHSDEDETESSDNEGEWD", "length": 527 }, "evidence": [ { "id": "E1BTH9", "url": "https://omabrowser.org/oma/group/E1BTH9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1BTH9", "url": "https://www.uniprot.org/uniprotkb/E1BTH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 460, 464 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BXF8-1", "uniprot_ac": "E1BXF8", "uniprot_id": "E1BXF8_CHICK", "mass": { "chemical_mass": 52830.0, "monoisotopic_mass": 52830.0 }, "refseq": { "ac": "XP_004938722", "name": "peptide chain release factor 1, mitochondrial isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938722" }, "gene_names": [ { "name": "MTRF1", "type": "recommended", "evidence": [ { "id": "E1BXF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" } ] }, { "name": "MTRF1", "type": "synonym", "evidence": [ { "id": "XP_004938722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938722" } ] } ], "protein_names": [ { "name": "Mitochondrial translation release factor 1", "type": "synonym", "evidence": [ { "id": "E1BXF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXF8/entry#names_and_taxonomy" } ] }, { "name": "peptide chain release factor 1, mitochondrial isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004938722", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938722" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938722" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BXF8", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTRF1", "url": "https://www.uniprot.org/uniprotkb/E1BXF8", "locus": { "chromosome": "1", "start_pos": 165756908, "end_pos": 165770097, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003169", "url": "https://www.ensembl.org/id/ENSGALG00010003169" } ] } } ], "crossref": [ { "id": "E1BXF8", "url": "https://alphafold.ebi.ac.uk/entry/E1BXF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016951", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016951", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418830", "url": "https://www.ncbi.nlm.nih.gov/gene/418830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ECQQSRS", "url": "https://omabrowser.org/oma/group/ECQQSRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X8I6", "url": "https://www.orthodb.org/?gene=A0A8V0X8I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XCN6", "url": "https://www.orthodb.org/?gene=A0A8V0XCN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFI0", "url": "https://www.orthodb.org/?gene=A0A8V0XFI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XJH8", "url": "https://www.orthodb.org/?gene=A0A8V0XJH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BXF8", "url": "https://www.orthodb.org/?gene=E1BXF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43804", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43804", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43804:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43804:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00472", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00472", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938722", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938722", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X8I6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XCN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XJH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXF8", "url": "https://www.uniprot.org/uniprotkb/E1BXF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BXF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPPQSIWLFKNLLSSCYCYGQLHNSPLPSVAKKISYVMRLHSCGFWRPESLLDTDRFTLSFHGWLRKKHQDSRALWKHEAVQKYLETLSKEYQQVDHLLNADSKNEFEQRTLRRRRADLSPVATAFQEIREAESELQELETMCRELDSRDEKQLLELALEEKETLDKKINTLCRKLFQLLVPKEKYDKSHVILEVTAGRTTGGDICQQFTKEMFEMYQNYADYKCWTFDILNYVPAEIGGLHHAAAHISGDDVYRHLKYEGGTHRVQRIPETGLSSRMQRIHTGTMSVIVLPQPEEVDVKVDPKDLRIDTFRAKGAGGQHVNKTDSAVRIVHLPTGVVVECQQERSQQMNKEIALRTLRAKLYQQIIEKQLSQEQSARKLQLGTRAQSERIRTYNFTQDRVTDHRISYDARNIKEILSGKEELDKLINRLLEFAEMEALTEYLENLQSVGGEGC", "length": 455, "header": "tr|E1BXF8-1|E1BXF8_CHICK Isoform 1 of Mitochondrial translation release factor 1 OS=Gallus gallus OX=9031 GN=MTRF1 PE=3 SV=2 CANONICAL=E1BXF8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X8I6-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF8/entry#A0A8V0X8I6-1", "sequence": { "sequence": "MKPPQSIWLFKNLLSSCYCYGQLHNSPLPSVAKKISYVMRLHSCGFWRPESLLDTDRFTLSFHGWLRKKHQDSRALWKHEAVQKYLETLSKEYQQVDHLLNADSKNEFEQRTLRRRRADLSPVATAFQEIREAESELQELETMCRELDSRDEKQLLELALEEKETLDKKINTLCRKLFQLLVPKEKYDKSHVILEVTAGRTTGGGLHHAAAHISGDDVYRHLKYEGGTHRVQRIPETGLSSRMQRIHTGTMSVIVLPQPEEVDVKVDPKDLRIDTFRAKGAGGQHVNKTDSAVRIVHLPTGVVVECQQERSQQMNKEIALRTLRAKLYQQIIEKQLSQEQSARKLQLGTRAQSERIRTYNFTQDRVTDHRISYDARNIKEILSGKEELDKLINRLLEFAEMEALTEYLENLQSVGGEGC", "length": 419, "header": "tr|A0A8V0X8I6-1|A0A8V0X8I6_CHICK Computationally mapped isoform of Mitochondrial translation release factor 1 OS=Gallus gallus OX=9031 GN=MTRF1 PE=3 SV=1 CANONICAL=E1BXF8-1" }, "locus": { "chromosome": "1", "start_pos": 165767884, "end_pos": 165757009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007382.1", "url": "https://www.ensembl.org/id/ENSGALT00010007382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004420.1", "url": "https://www.ensembl.org/id/ENSGALP00010004420.1" } ] } }, { "isoform_ac": "A0A8V0XCN6-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF8/entry#A0A8V0XCN6-1", "sequence": { "sequence": "MKPPQSIWLFKNLLSSCYCYGQLHNSPLPSVAKKISYVMRLHSCGFWRPESLLDTDRFTLSFHGWLRKKHQDSRALWKHEAVQKYLETLSKEYQQVDHLLNADSKNEFEQRTLRRRRADLSPVATAFQEIREAESELQELETMCRELDSRDEKQLLELALEEKETLDKKINTLCRKLFQLLVPKEKYDKSHVILEVTAGRTTGGDICQQFTKEMFEMYQNYADYKCWTFDILNYVPAEIGGLHHAAAHISGDDVYRHLKYEGGTHRVQRIPETGLSSRMQRIHTGTMSVIVLPQPEEVDVKVDPKDLRIDTFRAKGAGGQHVNKTDSAVRIVHLPTVECQQERSQQMNKEIALRTLRAKLYQQIIEKQLSQEQSARKLQLGTRAQSERIRTYNFTQDRVTDHRISYDARNIKEILSGKEELDKLINRLLEFAEMEALTEYLENLQSVGGEGC", "length": 452, "header": "tr|A0A8V0XCN6-1|A0A8V0XCN6_CHICK Computationally mapped isoform of Mitochondrial translation release factor 1 OS=Gallus gallus OX=9031 GN=MTRF1 PE=3 SV=1 CANONICAL=E1BXF8-1" }, "locus": { "chromosome": "1", "start_pos": 165767884, "end_pos": 165757009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007388.1", "url": "https://www.ensembl.org/id/ENSGALT00010007388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004424.1", "url": "https://www.ensembl.org/id/ENSGALP00010004424.1" } ] } }, { "isoform_ac": "A0A8V0XFI0-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF8/entry#A0A8V0XFI0-1", "sequence": { "sequence": "MKPPQSIWLFKNLLSSCYCYGQLHNSPLPSVAKKISYVMRLHSCGFWRPESLLDTDRFTLSFHGWLRKKHQDSRALWKHEAVQKYLETLSKEYQQVDHLLNADSKNEFEQRTLRRRRADLSPVATAFQEIREAESELQELETMCRELDSRDEKQLLELALEEKETLDKKINTLCRKLFQLLVPKEKYDKSHVILEVTAGRTTGGDICQQFTKEMFEMYQNYADYKCWTFDILNYVPAEIGGLHHAAAHISGDDVYRHLKYEGGTHRVQRIPETGLSSRMQRIHTGTMSVIVLPQPEEVDVKVDPKDLRIDTFRAKGAGGQHVNKTDSAVRIVHLPTGVVVECQQERSQQMNKEIALRTLRAKLYQQIIEKQLSQEQSARKLQEILSGKEELDKLINRLLEFAEMEALTEYLENLQSVGGEGC", "length": 422, "header": "tr|A0A8V0XFI0-1|A0A8V0XFI0_CHICK Computationally mapped isoform of Mitochondrial translation release factor 1 OS=Gallus gallus OX=9031 GN=MTRF1 PE=3 SV=1 CANONICAL=E1BXF8-1" }, "locus": { "chromosome": "1", "start_pos": 165767884, "end_pos": 165757009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007386.1", "url": "https://www.ensembl.org/id/ENSGALT00010007386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004422.1", "url": "https://www.ensembl.org/id/ENSGALP00010004422.1" } ] } }, { "isoform_ac": "A0A8V0XJH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF8/entry#A0A8V0XJH8-1", "sequence": { "sequence": "MQTCSGGRIRNNMKPPQSIWLFKNLLSSCYCYGQLHNSPLPSVAKKISYVMRLHSCGFWRPESLLDTDRFTLSFHGWLRKKHQDSRALWKHEAVQKYLETLSKEYQQVDHLLNADSKNEFEQRTLRRRRADLSPVATAFQEIREAESELQELETMCRELDSRDEKQLLELALEEKETLDKKINTLCRKLFQLLVPKEKYDKSHVILEVTAGRTTGGDICQQFTKEMFEMYQNYADYKCWTFDILNYVPAEIGGLHHAAAHISGDDVYRHLKYEGGTHRVQRIPETGLSSRMQRIHTGTMSVIVLPQPEEVDVKVDPKDLRIDTFRAKGAGGQHVNKTDSAVRIVHLPTGVVVECQQERSQQMNKEIALRTLRAKLYQQIIEKQLSQEQSARKLQLGTRAQSERIRTYNFTQDRVTDHRISYDARNIKEILSGKEELDKLINRLLEFAEMEALTEYLENLQSVGGEGC", "length": 467, "header": "tr|A0A8V0XJH8-1|A0A8V0XJH8_CHICK Computationally mapped isoform of Mitochondrial translation release factor 1 OS=Gallus gallus OX=9031 GN=MTRF1 PE=3 SV=1 CANONICAL=E1BXF8-1" }, "locus": { "chromosome": "1", "start_pos": 165769141, "end_pos": 165757009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007377.1", "url": "https://www.ensembl.org/id/ENSGALT00010007377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004416.1", "url": "https://www.ensembl.org/id/ENSGALP00010004416.1" } ] } }, { "isoform_ac": "E1BXF8-1", "url": "https://www.uniprot.org/uniprotkb/E1BXF8/entry#E1BXF8-1", "sequence": { "sequence": "MKPPQSIWLFKNLLSSCYCYGQLHNSPLPSVAKKISYVMRLHSCGFWRPESLLDTDRFTLSFHGWLRKKHQDSRALWKHEAVQKYLETLSKEYQQVDHLLNADSKNEFEQRTLRRRRADLSPVATAFQEIREAESELQELETMCRELDSRDEKQLLELALEEKETLDKKINTLCRKLFQLLVPKEKYDKSHVILEVTAGRTTGGDICQQFTKEMFEMYQNYADYKCWTFDILNYVPAEIGGLHHAAAHISGDDVYRHLKYEGGTHRVQRIPETGLSSRMQRIHTGTMSVIVLPQPEEVDVKVDPKDLRIDTFRAKGAGGQHVNKTDSAVRIVHLPTGVVVECQQERSQQMNKEIALRTLRAKLYQQIIEKQLSQEQSARKLQLGTRAQSERIRTYNFTQDRVTDHRISYDARNIKEILSGKEELDKLINRLLEFAEMEALTEYLENLQSVGGEGC", "length": 455, "header": "tr|E1BXF8-1|E1BXF8_CHICK Isoform 1 of Mitochondrial translation release factor 1 OS=Gallus gallus OX=9031 GN=MTRF1 PE=3 SV=2 CANONICAL=E1BXF8-1" }, "locus": { "chromosome": "1", "start_pos": 165767884, "end_pos": 165757009, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010007379.1", "url": "https://www.ensembl.org/id/ENSGALT00010007379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010004417.1", "url": "https://www.ensembl.org/id/ENSGALP00010004417.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" } ], "orthologs": [ { "uniprot_canonical_ac": "A2RVR7-1", "protein_name": "Peptide chain release factor 1, mitochondrial", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRVLIRPNFLSNLIRYCSRGTHSHDRSLRSVLSSNMIRLYTTGMEPQLSPDLIKIMDQRLSAIEHRNAVLQKLINQPEYSPEEFSRANKELRKLRDSMLLINDLRAKQKEIDGLKSLVSESSDDKDMLDLAVGELDEAVEEEKRLQTLLLKSLLPKDEADERDCILEVRAGTGGEEASLFAMDIFRMYERYSQKKGWKFDIVDITESDMKGYKEASAAICGASVYGKLKFESGIHRVQRIPITEKSGRIHTSAISVAILPQADEVDVQLRNEDLRIDTYRSGGSGGQHANTTNSAVRIIHLPTGMMVSIQDERSQHMNRAKALKVLCARLYEIERLRIQSSRSKLRSDQIGSGDRSGRIRTYNFPQGRVTDHRVGITHHAIEDMMQGENLDMFIDALLLRQEMDAIASFSSTS", "length": 413 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F1RJ87-1", "protein_name": "Mitochondrial translation release factor 1", "gene_name": "MTRF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNRHLYVWLCRHPSLHRHRQCHVHLRSHRLTQTHLDTRPGAFRQDRNHLLCRLLNKSWSRRYCHQDTRMQWRHKALQKYMEDLSKEYQTLDRCLQHISAPEGDRRSLNRRHAELAPLAVIYKEIQEAEQAIEELESMCKSLNKQDEKQLQELALEEKRTIAQKINMLYHELFQSLVPKEKYDKNDVILEVTSGRTTGGDICQQFTREIFDMYQNYSSYKHWTFELLNYTPADYGGLHHAAARISGANVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKVDPKDLRIDTFRAKGAGGQHVNTTDSAVRLVHVPTGLVVECQQERSQIKNKEIALRVLRARLYQQIIEKEKCQQQSARKLQVGTRAQSERIRTYNFTQDRVTDHRIAYEVRNIKEFLCGEKCLDLLIQRLLQTADEEAITEFLDENLKSAK", "length": 446 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HGU2-1", "protein_name": "Peptide chain release factor 1, mitochondrial", "gene_name": "Mtrf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSHHLCIHLFRNPSYTRRHVFLYCQRFRQISLDTRLWDFKQNKSHVLHQVLNKSWSRSYCHQDPKMLWKHKALQKYMEGLNEEYQTLDGCLQDISGNEDSRRALCRRHAKLAPLAAIYQEIQEAEQAIEELESMCKTLHKQDEKQLQELVSEERQIIDQKINTLYSELLEQLVPKEKYDKSDVILEVTSGRTTGGDICQQFTREIFDMYQNYSYYKHWKFELLNYTPADYGGLHHAAARISGDSVYKHLKYEGGIHRVQRIPDVGLSSRMQRIHTGTMSVIVLLQPDEVDVKVDPRDLRIDTFRSRGPGGQHVNTTDSAVRLVHIPTGLVVECQQERSQLKNKEIALRVLRARLYQQILEKDKCQQQSARKLQVGTRAQSERIRTYNFTQDRVTDHRIAFEVRDIKEFLRGEKCLDQLIQRLLQSADEEAIAEFLDESLKSVK", "length": 443 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0RDC8-1", "protein_name": "Mitochondrial translation release factor 1", "gene_name": "Mtrf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFHLCVWLFRNLSSLSACSQRHVFLYGQQFRQINLDPRLWNFRQNKTHVLYRLLNKSWSRGYCQGTRKLWKHKALQKYMEGLNDEYQSLDQCLQDISEDEGDRRASHRRHAELAPLVAVYQEIQEAEQAIEELESMCKSLNKQDEKQLQELVSEERQIIDQKIHRLYSELLEHLVPKEKCDRSNVILEVTSGRTTGGDICQQFTREIFDMYQNYSYYKHWRFELLNYTPADYGGLHHAAARISGDSVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKVDPRDLRVDTFRARGAGGQHVNTTDSAVRLVHIPTGLVVECQQERSQLKNKEIALRVLRARLYQQIIEKDKCQQQNARKLQEFLRGEKCLDQLIERLLQSADEEAIAEFLDESLQSVK", "length": 413 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75570-1", "protein_name": "Peptide chain release factor 1, mitochondrial", "gene_name": "MTRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRHLCVWLFRHPSLNGYLQCHIQLHSHQFRQIHLDTRLQVFRQNRNCILHLLSKNWSRRYCHQDTKMLWKHKALQKYMENLSKEYQTLEQCLQHIPVNEENRRSLNRRHAELAPLAAIYQEIQETEQAIEELESMCKSLNKQDEKQLQELALEERQTIDQKINMLYNELFQSLVPKEKYDKNDVILEVTAGRTTGGDICQQFTREIFDMYQNYSCYKHWQFELLNYTPADYGGLHHAAARISGDGVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKLDPKDLRIDTFRAKGAGGQHVNKTDSAVRLVHIPTGLVVECQQERSQIKNKEIAFRVLRARLYQQIIEKDKRQQQSARKLQVGTRAQSERIRTYNFTQDRVSDHRIAYEVRDIKEFLCGGKGLDQLIQRLLQSADEEAIAELLDEHLKSAK", "length": 445 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3MHI7-1", "protein_name": "Peptide chain release factor 1, mitochondrial", "gene_name": "MTRF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRRHLFAWLFRHLSLNGHLQCHVHRHSHQLTQIPLDTRLWVFRRNRNHTVHRLLNKNCSRRYCHQDTSMLWKHKALQKYMEDLNKEYQTLDHCLHHISASEGDRRSLTRRHAELAPLAVIYKEIQEAEQAIEELESMCKSLNKQDEKQLQELALEERQTIAQKINMLYSELFQSLLPKEKYDKNDVILEVTSGRTTGGDICQQFTREIFDMYQNYSSYKHWRFELLNYTPADYGGLHHAAARISGDNVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPHPDEVDVKVDPKDLRIDTFRAKGAGGQHVNTTDSAVRLVHIPTGLVVECQQERSQIKNKEIALRVLRARLYQQIIEKDKCQQRSARKLQVGTRAQSERIRTYNFTQDRVTDHRIAYEVRNIKEFLCGEKCLDQLIQRLLQSADEEAITEFLDENLKSVK", "length": 447 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54RE7-1", "protein_name": "Peptide chain release factor 1", "gene_name": "prfA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFRSLNKLLISNNLIIKKNNIIIPYNYKFSIKNNNNNNNNFIYRNFCNNNNNKNNNNNNNNIDELFNKTSIPPNIVFRLNLMGKKSKELRNMIDSNMGLGQSEIKKISKELQETAEPLGYFGDLIEKLKELKELQTMLVEETDEDGKQMIKSDINKLKQEEIEPLEKQLLFSLLPGSKDDAGDAILEIRAGTGGSEAQLFTQDVYEMYRSYCLQKGWTFEPLELSVTEVGGYRDVTVSVSGKGVFGFLKYESGVHRVQRVPLTETQGRIHTSTITVAILPEPKDVDIQIHDRDLKVDIYRSSGNGGQSVNTTDSAVRITHLPTGITVAMQDERSQHQNRSKAMKILKARIYERERIRLQNERVSERNAQIGSALRSERIRTYNYPQDRITDHRVSINGNLNSCMNSDGLDSFIDEILVEFHTKELEELLS", "length": 430 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K126-1", "protein_name": "Peptide chain release factor 1, mitochondrial", "gene_name": "Mtrf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHHLCIWLFRNPFLRACPQRHVFLSCQQFRQISLDTRPWNFRQKKTHVLYQLLNKSWSRGCCHQGTRKLWKHKALQKYMEDLNKEYQTLDQCLQGISENEGDRRALHRRHAQLAPLAAVYQEIQEAEQAIEELESLCKSLNKQDEKQLQELVSEERQIIDQKIHRLYSELLERLVPKEKYDWSDVILEVTSGRTTGGDICQQFTREIFDMYQNYSYYKHWKFELLNYTPADYGGLHHAAARISGDSVYKHLKYEGGIHRVQRIPEVGLSSRMQRIHTGTMSVIVLPQPDEVDVKVDPKDLRVDTFRARGAGGQHVNTTDSAVRLVHIPTGLVVECQQERSQLKNKEIALRVLRARLYQQIIEKDRCQQQNARKLQVGTRAQSERIRTYNFTQDRVTDHRIAYEVRDIKEFLRGEKCLDQLIERLLQSADEEAISEFLDESLQSVK", "length": 446 }, "evidence": [ { "id": "E1BXF8", "url": "https://omabrowser.org/oma/group/E1BXF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1BXF8", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BXF8", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial translational termination", "id": "GO:0070126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070126", "evidence": [ { "database": "UniProtKB", "id": "E1BXF8", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "translation release factor activity, codon specific", "id": "GO:0016149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016149", "evidence": [ { "database": "UniProtKB", "id": "E1BXF8", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" } ], "pmid": "" }, { "name": "translation release factor activity", "id": "GO:0003747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003747", "evidence": [ { "database": "UniProtKB", "id": "E1BXF8", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BXF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BXF8" }, { "id": "PS00745", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00745" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Prokaryotic-type class I peptide chain release factors", "eco_id": "ECO_0000259", "start_pos": 313, "end_pos": 329, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 323, "end_pos": 325 }, { "start_pos": 396, "end_pos": 398 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQR4-1", "uniprot_ac": "E1BQR4", "uniprot_id": "E1BQR4_CHICK", "mass": { "chemical_mass": 68318.0, "monoisotopic_mass": 68318.0 }, "refseq": { "ac": "XP_015131991", "name": "kelch-like protein 8 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131991" }, "gene_names": [ { "name": "KLHL8", "type": "recommended", "evidence": [ { "id": "E1BQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ] }, { "name": "KLHL8", "type": "synonym", "evidence": [ { "id": "XP_015131991", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131991" } ] } ], "protein_names": [ { "name": "Kelch like family member 8", "type": "synonym", "evidence": [ { "id": "E1BQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQR4/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 8 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015131991", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131991" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131991", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131991" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL8", "url": "https://www.uniprot.org/uniprotkb/E1BQR4", "locus": { "chromosome": "4", "start_pos": 45319096, "end_pos": 45302755, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003816", "url": "https://www.ensembl.org/id/ENSGALG00010003816" } ] } } ], "crossref": [ { "id": "E1BQR4", "url": "https://alphafold.ebi.ac.uk/entry/E1BQR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011017", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011017", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18238", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18238", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18448", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18448", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422589", "url": "https://www.ncbi.nlm.nih.gov/gene/422589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422589", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRPMSTS", "url": "https://omabrowser.org/oma/group/VRPMSTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XEQ2", "url": "https://www.orthodb.org/?gene=A0A8V0XEQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XHH0", "url": "https://www.orthodb.org/?gene=A0A8V0XHH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQR4", "url": "https://www.orthodb.org/?gene=E1BQR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF480", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF480", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015131991", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131991", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XEQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XHH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQR4-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASESMVPEQAKQHPMKGKRRPQQQQTRSSSGDGEDDIFVFEANEAWKDFHSSLLHFFEAGELCDVTLKVGTKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVAKACCEYMKLHFHPSNCLAVRSFAESHNRIDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLANPQHHATWLDEILAQVRLPLLPICFLMGVVAKEEIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKQTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVGGRVYAVGGHDGNEHLGSMEVFDPLTNKWMIKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDRWSAVAPMNTPRGGVGSVALMNHVYAVGGNDGIASLSSVEKYDPHLDKWMEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERFDPRSDKWEYVAELTTPRGGVGIATLMGRIFAVGGHNGNAYLNTVEAFDPIVNRWELVGSVSHCRAGAGVAVCACLSSQIRDVGQGSSNVVDCM", "length": 617, "header": "tr|E1BQR4-1|E1BQR4_CHICK Isoform 1 of Kelch like family member 8 OS=Gallus gallus OX=9031 GN=KLHL8 PE=4 SV=1 CANONICAL=E1BQR4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XEQ2-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR4/entry#A0A8V0XEQ2-1", "sequence": { "sequence": "MASESMVPEQAKQHPMKGKRRPQQQQTRSSSGDGEDDIFVFEANEAWKDFHSSLLHFFEAGELCDVTLKVGTKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVAKACCEYMKLHFHPSNCLAVRSFAESHNRIDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLANPQHHATWLDEILAQVRLPLLPICFLMGVVAKEEIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKQTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVGGRVYAVGGHDGNEHLGSMEVFDPLTNKWMIKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDRWSAVAPMNTPRGGVGSVALMVSLFPCRSGPGSRPAFQISSKSSKQSFPVQLFQNHVYAVGGNDGIASLSSVEKYDPHLDKWMEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERFDPRSDKWEYVAELTTPRGGVGIATLMGRIFAVGGHNGNAYLNTVEAFDPIVNRWELVGSVSHCRAGAGVAVCACLSSQIRDVGQGSSNVVDCM", "length": 650, "header": "tr|A0A8V0XEQ2-1|A0A8V0XEQ2_CHICK Computationally mapped isoform of Kelch like family member 8 OS=Gallus gallus OX=9031 GN=KLHL8 PE=4 SV=1 CANONICAL=E1BQR4-1" }, "locus": { "chromosome": "4", "start_pos": 45318393, "end_pos": 45309432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008829.1", "url": "https://www.ensembl.org/id/ENSGALT00010008829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005173.1", "url": "https://www.ensembl.org/id/ENSGALP00010005173.1" } ] } }, { "isoform_ac": "A0A8V0XHH0-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR4/entry#A0A8V0XHH0-1", "sequence": { "sequence": "MASESMVPEQAKQHPMKGKRRPQQQQTRSSSGDGEDDIFVFEANEAWKDFHSSLLHFFEAGELCDVTLKVGTKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVAKACCEYMKLHFHPSNCLAVRSFAESHNRIDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLANPQHHATWLDEILAQVRLPLLPICFLMGVVAKEEIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKQTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVGGRVYAVGGHDGNEHLGSMEVFDPLTNKWMIKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDRWSAVAPMNTPRGGVGSVALMNHVYAVGGNDGIASLSSVEKYDPHLDKWMEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERFDPRSDKWEYVAELTTPRGGVGIATLMGRIFAVGGHNGNAYLNTVEAFDPIVGTRWLCVALQSWGRRCCVRLPQQPDP", "length": 601, "header": "tr|A0A8V0XHH0-1|A0A8V0XHH0_CHICK Computationally mapped isoform of Kelch like family member 8 OS=Gallus gallus OX=9031 GN=KLHL8 PE=4 SV=1 CANONICAL=E1BQR4-1" }, "locus": { "chromosome": "4", "start_pos": 45318353, "end_pos": 45309432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008827.1", "url": "https://www.ensembl.org/id/ENSGALT00010008827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005171.1", "url": "https://www.ensembl.org/id/ENSGALP00010005171.1" } ] } }, { "isoform_ac": "E1BQR4-1", "url": "https://www.uniprot.org/uniprotkb/E1BQR4/entry#E1BQR4-1", "sequence": { "sequence": "MASESMVPEQAKQHPMKGKRRPQQQQTRSSSGDGEDDIFVFEANEAWKDFHSSLLHFFEAGELCDVTLKVGTKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVAKACCEYMKLHFHPSNCLAVRSFAESHNRIDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLANPQHHATWLDEILAQVRLPLLPICFLMGVVAKEEIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKQTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVGGRVYAVGGHDGNEHLGSMEVFDPLTNKWMIKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDRWSAVAPMNTPRGGVGSVALMNHVYAVGGNDGIASLSSVEKYDPHLDKWMEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERFDPRSDKWEYVAELTTPRGGVGIATLMGRIFAVGGHNGNAYLNTVEAFDPIVNRWELVGSVSHCRAGAGVAVCACLSSQIRDVGQGSSNVVDCM", "length": 617, "header": "tr|E1BQR4-1|E1BQR4_CHICK Isoform 1 of Kelch like family member 8 OS=Gallus gallus OX=9031 GN=KLHL8 PE=4 SV=1 CANONICAL=E1BQR4-1" }, "locus": { "chromosome": "4", "start_pos": 45318393, "end_pos": 45309432, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008830.1", "url": "https://www.ensembl.org/id/ENSGALT00010008830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005174.1", "url": "https://www.ensembl.org/id/ENSGALP00010005174.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422589", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U1F7-1", "protein_name": "Kelch-like protein 8", "gene_name": "KLHL8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASESTNAKQARNRFTKGKRQPHQQIKNRSSISDGDGEDFFIFEANEAWKEFHGSLLQFYENGELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRIDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIEDEKQVYSAAIKWLLANPQHHSKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKQTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDNTCFNDVERYDIESDQWSTVAPMNTPRGGVGSVALVNHVYAVGGNDGVASLSSVERYDPHLDKWIEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNRWELVGSVSHCRAGAGVAVCACLTSQIRDVGHGSSNVVDCM", "length": 619 }, "evidence": [ { "id": "E1BQR4", "url": "https://omabrowser.org/oma/group/E1BQR4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9S186-1", "protein_name": "Kelch-like protein 8", "gene_name": "KLHL8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASEAVNAKQARNRFTKGKRQQQIKNRSSLGDGDGEDSFLFEANEAWKDFHGSLLQFYENGELCDVTLKVGSKLISCHKLALACVIPYFKAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRVDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYSAAIKWLLANPQHHPLWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDNTCFNDVERYDIESDQWSTVAPMNTPRGGVGSVALVNHVYAVGGNDGVASLSSVERYDPHLDKWIEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNRWELVGSVSHCRAGAGVAVCACLTSQIRDVGHGSSNVVDCM", "length": 617 }, "evidence": [ { "id": "E1BQR4", "url": "https://omabrowser.org/oma/group/E1BQR4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LYQ9-1", "protein_name": "Kelch-like family member 8", "gene_name": "Klhl8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASESTNGKLARSHVTKGRRQQQQQQQVRSRSSVSECDGDDSFIFEANEAWKDFHGSLLGFYENGELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMSEAKQALIEIRDFDGDAVEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRTDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYSVRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINTNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMVKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMNTPRGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWVEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM", "length": 621 }, "evidence": [ { "id": "E1BQR4", "url": "https://omabrowser.org/oma/group/E1BQR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3III0-1", "protein_name": "Kelch-like protein 8", "gene_name": "Klhl8", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASESTNGKQARSHVTKGRRQHQHQPARSRSSVSECEGDDSFIFEANEAWKDFHSSLLRFYENGELCDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAKQALIEIRDFDGDAVEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRIDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHSKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYTVRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMNTPRGGVGSVALVNHVYAVGGNDGVASLSSVERYHPHLDKWIEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM", "length": 620 }, "evidence": [ { "id": "E1BQR4", "url": "https://omabrowser.org/oma/group/E1BQR4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P59280-1", "protein_name": "Kelch-like protein 8", "gene_name": "Klhl8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASESTNGKQARSHVTKGRRQYQHQHQQQQQQQQQVRSRSSVSECDGDDSFIFEANEAWKDFHGSLLGFYENGELCDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMSEAKQALIEIRDFDGDAVEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMQLHFHPSNCLAVRAFAESHNRIDLMDMADQYACEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYTVRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPMNTPRGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWIEVKEMGQRRAGNGVSELHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNKWELVGPVSHCRAGAGVAVCDCLTSQIRDVGHGSTNVVDCM", "length": 629 }, "evidence": [ { "id": "E1BQR4", "url": "https://omabrowser.org/oma/group/E1BQR4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2G9-1", "protein_name": "Kelch-like protein 8", "gene_name": "KLHL8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASDSMSSKQARNHITKGKRQQQHQQIKNRSSISDGDGEDSFIFEANEAWKDFHGSLLRFYENGELCDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAKQTLIEIRDFDGDAIEDLVKFVYSSRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRIDLMDMADQYACDHFTEVVECEDFVSVSPQHLHKLLSSSDLNIENEKQVYNAAIKWLLANPQHHSKWLDETLAQVRLPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSRAVPDFEYSIRTTPRKHTAGVLFCVGGRGGSGDPFRSIECYSINKNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLGSMEMFDPLTNKWMMKASMNTKRRGIALASLGGPIYAIGGLDDNTCFNDVERYDIESDQWSTVAPMNTPRGGVGSVALVNHVYAVGGNDGMASLSSVERYDPHLDKWIEVKEMGQRRAGNGVSKLHGCLYVVGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDPVLNRWELVGSVSHCRAGAGVAVCSCLTSQIRDVGHGSNNVVDCM", "length": 620 }, "evidence": [ { "id": "E1BQR4", "url": "https://omabrowser.org/oma/group/E1BQR4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E1BQR4", "url": "https://www.uniprot.org/uniprotkb/E1BQR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BW95-1", "uniprot_ac": "E1BW95", "uniprot_id": "E1BW95_CHICK", "mass": { "chemical_mass": 22721.0, "monoisotopic_mass": 22721.0 }, "refseq": { "ac": "XP_046757163", "name": "platelet glycoprotein Ib beta chain", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757163" }, "gene_names": [ { "name": "GP1BB", "type": "recommended", "evidence": [ { "id": "E1BW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ] }, { "name": "GP1BB", "type": "synonym", "evidence": [ { "id": "XP_046757163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757163" } ] } ], "protein_names": [ { "name": "Glycoprotein Ib platelet subunit beta", "type": "synonym", "evidence": [ { "id": "E1BW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW95/entry#names_and_taxonomy" } ] }, { "name": "platelet glycoprotein Ib beta chain", "type": "synonym", "evidence": [ { "id": "XP_046757163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757163" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046757163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757163" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GP1BB", "url": "https://www.uniprot.org/uniprotkb/E1BW95", "locus": { "chromosome": "15", "start_pos": 806541, "end_pos": 802149, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024525", "url": "https://www.ensembl.org/id/ENSGALG00010024525" } ] } } ], "crossref": [ { "id": "ENSGALG00000021529", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021529", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107051576", "url": "https://www.ncbi.nlm.nih.gov/gene/107051576", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107051576", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107051576", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPVPCKC", "url": "https://omabrowser.org/oma/group/CPVPCKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AXX7", "url": "https://www.orthodb.org/?gene=A0A3Q3AXX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BW95", "url": "https://www.orthodb.org/?gene=E1BW95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22650", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22650", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22650:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22650:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-430116", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-430116", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769739", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9769743", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769743", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9935598", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9935598", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046757163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3AXX7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AXX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AXX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AXX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BW95-1", "url": "https://www.uniprot.org/uniprotkb/E1BW95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSGILFLSLLGFLPSVIPTCPLPCKCATNIIDCMSKGLTVTRLPAAFRPSAEIINLSYNRLTSIPSGLFDNLNSLQAVHLQGNPWECDCDILYLRSWLQWQQNRTFYRDVRCASPAHLQGRVVAYLTEDEIISTCQYWYCSLALFSQLVLIILLFLQAILVIFIIIYLQRFRRMAAEARSTTRDLYQRADTWSLQEQ", "length": 198, "header": "tr|E1BW95-1|E1BW95_CHICK Isoform 1 of Glycoprotein Ib platelet subunit beta OS=Gallus gallus OX=9031 GN=GP1BB PE=4 SV=2 CANONICAL=E1BW95-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AXX7-1", "url": "https://www.uniprot.org/uniprotkb/E1BW95/entry#A0A3Q3AXX7-1", "sequence": { "sequence": "MNSGILFLSLLGFLPSVIPTCPLPCKCATNIIDCMSKGLTVTRLPAAFRPSAEIINLSYNRLTSIPSGLFDNLNSLQAVHLQGNPWECDCDILYLRSWLQWQQNRTFYRDVRCASPAHLQGRVVAYLTEDEIISTCQYWYCSLALFSQLVLIILLFLQAILVIFIIIYLQRFRRMAAEARSTTRDLYQRADTWSLQEHPRKP", "length": 202, "header": "tr|A0A3Q3AXX7-1|A0A3Q3AXX7_CHICK Computationally mapped isoform of Glycoprotein Ib platelet subunit beta OS=Gallus gallus OX=9031 GN=GP1BB PE=4 SV=1 CANONICAL=E1BW95-1" }, "locus": { "chromosome": "15", "start_pos": 806069, "end_pos": 805205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059824.1", "url": "https://www.ensembl.org/id/ENSGALT00010059824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036584.1", "url": "https://www.ensembl.org/id/ENSGALP00010036584.1" } ] } }, { "isoform_ac": "E1BW95-1", "url": "https://www.uniprot.org/uniprotkb/E1BW95/entry#E1BW95-1", "sequence": { "sequence": "MNSGILFLSLLGFLPSVIPTCPLPCKCATNIIDCMSKGLTVTRLPAAFRPSAEIINLSYNRLTSIPSGLFDNLNSLQAVHLQGNPWECDCDILYLRSWLQWQQNRTFYRDVRCASPAHLQGRVVAYLTEDEIISTCQYWYCSLALFSQLVLIILLFLQAILVIFIIIYLQRFRRMAAEARSTTRDLYQRADTWSLQEQ", "length": 198, "header": "tr|E1BW95-1|E1BW95_CHICK Isoform 1 of Glycoprotein Ib platelet subunit beta OS=Gallus gallus OX=9031 GN=GP1BB PE=4 SV=2 CANONICAL=E1BW95-1" }, "locus": { "chromosome": "15", "start_pos": 805798, "end_pos": 805205, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059827.1", "url": "https://www.ensembl.org/id/ENSGALT00010059827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036587.1", "url": "https://www.ensembl.org/id/ENSGALP00010036587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107051576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107051576", "resource": "KEGG Pathway" }, { "id": "R-GGA-430116", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-430116", "resource": "Reactome", "description": "GP1b-IX-V activation signalling" }, { "id": "R-GGA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" }, { "id": "R-GGA-9769743", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769743", "resource": "Reactome", "description": "Amplification and propagation of coagulation cascade" }, { "id": "R-GGA-9935598", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9935598", "resource": "Reactome", "description": "FXIIa, PKa-dependent activation of coagulation pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32U0D4-1", "protein_name": "Platelet glycoprotein Ib beta chain isoform X1", "gene_name": "gp1bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPKKATYCNNTPVVLKVGGRDPPKRLGDNEGGSPVCVCVCAGMRSVVLVFFLSAMAAVVQGSCPHVCSCSAGVVDCSNRALTTATLPSSFPASTTELLLNENHLTALPTGLLDALPALRRVALHGNSWACDCAILYLRGWMLKRGSDPSMRNVSCSSPAHLRGRLIVYLPEQELLDSCRYWLCNLALASQISLLVFIGVQALLLASVIFFLRRFERLTEEAQRTAAESFTAEENADHNSEYVMLKDRSM", "length": 250 }, "evidence": [ { "id": "E1BW95", "url": "https://omabrowser.org/oma/group/E1BW95/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B7TY21-1", "protein_name": "Platelet glycoprotein Ib beta chain", "gene_name": "GP1BB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGSGPRGALSLLLLLLAPPIRPAVGCPAPCRCAGTLVDCGRRGLTWASLPAAFPPDTTELVLTGNNLTALPLGLLDALPALRTAHLGANPWRCDCHLVPLRAWLADRPEREPYRDLRCAAPPALRGRLLPYLAEEELRAACTPGALCHWALAAQLLLLGLGLLHALLLALLLCRLQRLRARIARRWALITPLAAEPATTEQSY", "length": 203 }, "evidence": [ { "id": "E1BW95", "url": "https://omabrowser.org/oma/group/E1BW95/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P13224-1", "protein_name": "Platelet glycoprotein Ib beta chain", "gene_name": "GP1BB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRARARARAAARLSLTDPLVAERAGTDES", "length": 206 }, "evidence": [ { "id": "E1BW95", "url": "https://omabrowser.org/oma/group/E1BW95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJM7-1", "protein_name": "Platelet glycoprotein Ib beta chain", "gene_name": "Gp1bb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSRPRGALSLLLLLLAPPSRPASGCPAPCRCSETRVDCGRRGLTWASLPAAFPPDTTELVLTDNNLTALPPGLLDTLPALRRVHLGANPWRCDCRLLPLRAWLAGRPEREFYRDLRCVAPLALRGRLLPYVAEDELRAACAPGLLCWGALVAQLALLVLGLLHALLLALLLSRLRRLRAQARARSTREFSLTAPLVAESAGGGAS", "length": 206 }, "evidence": [ { "id": "E1BW95", "url": "https://omabrowser.org/oma/group/E1BW95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ], "pmid": "" }, { "name": "blood coagulation, intrinsic pathway", "id": "GO:0007597", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007597", "evidence": [ { "database": "UniProtKB", "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ], "pmid": "" }, { "name": "positive regulation of platelet activation", "id": "GO:0010572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010572", "evidence": [ { "database": "UniProtKB", "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "E1BW95", "url": "https://www.uniprot.org/uniprotkb/E1BW95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BW95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW95" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 135, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BVN1-1", "uniprot_ac": "E1BVN1", "uniprot_id": "E1BVN1_CHICK", "mass": { "chemical_mass": 31181.0, "monoisotopic_mass": 31181.0 }, "refseq": { "ac": "XP_421989", "name": "metaxin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421989" }, "gene_names": [ { "name": "MTX2", "type": "recommended", "evidence": [ { "id": "E1BVN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ] }, { "name": "MTX2", "type": "synonym", "evidence": [ { "id": "XP_421989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421989" } ] } ], "protein_names": [ { "name": "Metaxin-2", "type": "recommended", "evidence": [ { "id": "E1BVN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVN1/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial outer membrane import complex protein 2", "type": "synonym", "evidence": [ { "id": "E1BVN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVN1/entry#names_and_taxonomy" } ] }, { "name": "metaxin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421989" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421989" } ] }, { "annotation": "Involved in transport of proteins into the mitochondrion.", "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1#function" }, { "database": "UniProtKB", "id": "ARBA00058396", "url": "https://www.uniprot.org/uniprotkb/ARBA00058396#function" }, { "database": "UniProtKB", "id": "A0A8V1A3V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3V2#function" }, { "database": "UniProtKB", "id": "A0A8V1A089", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A089#function" }, { "database": "UniProtKB", "id": "A0A8V0ZYH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYH8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTX2", "url": "https://www.uniprot.org/uniprotkb/E1BVN1", "locus": { "chromosome": "7", "start_pos": 15820475, "end_pos": 15864073, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024183", "url": "https://www.ensembl.org/id/ENSGALG00010024183" } ] } } ], "crossref": [ { "id": "E1BVN1", "url": "https://alphafold.ebi.ac.uk/entry/E1BVN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009264", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03079", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03079", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424138", "url": "https://www.ncbi.nlm.nih.gov/gene/424138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YFQTRCL", "url": "https://omabrowser.org/oma/group/YFQTRCL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYH8", "url": "https://www.orthodb.org/?gene=A0A8V0ZYH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A089", "url": "https://www.orthodb.org/?gene=A0A8V1A089", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3V2", "url": "https://www.orthodb.org/?gene=A0A8V1A3V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVN1", "url": "https://www.orthodb.org/?gene=E1BVN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12289:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12289:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17172", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17172", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A089", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A089", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A089-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A089-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3V2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BVN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVAEAFMNQLAAAEPWPENAALYQQLKEDQILLSDNAASLAVQAFLQMCNLPVRVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDDVTVEEITHPRYGSPYPWPLNRILSYQKQWEIRRKMKAIGWAGKSLEQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLFTILTTQLITDELSEKVKNYGNLTAFCRRIEQQYFEGHDKDGSAAASARSAKRSLLR", "length": 276, "header": "tr|E1BVN1-1|E1BVN1_CHICK Isoform 1 of Metaxin-2 OS=Gallus gallus OX=9031 GN=MTX2 PE=1 SV=3 CANONICAL=E1BVN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYH8-1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1/entry#A0A8V0ZYH8-1", "sequence": { "sequence": "MSLVAEAFMNQLAAAEPWPENAALYQQLKEDQILLSDNAASLAVQAFLQMCNLPVRVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDDVTVEEITHPRYGSPYPWPLNRILSYQKQWEIRRKMKAIGWAGKSLEQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLFTILTTQLITDELSEKVKNYGNLTAFCRRIEQQYFEGHDKDGSAAASARSAKRSESDPDLNKIWSQIFTPECFCLAACQMPSSCKCVTHLGVQLVELMR", "length": 318, "header": "tr|A0A8V0ZYH8-1|A0A8V0ZYH8_CHICK Computationally mapped isoform of Metaxin-2 OS=Gallus gallus OX=9031 GN=MTX2 PE=1 SV=1 CANONICAL=E1BVN1-1" }, "locus": { "chromosome": "7", "start_pos": 15863622, "end_pos": 15821479, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058999.1", "url": "https://www.ensembl.org/id/ENSGALT00010058999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035963.1", "url": "https://www.ensembl.org/id/ENSGALP00010035963.1" } ] } }, { "isoform_ac": "A0A8V1A089-1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1/entry#A0A8V1A089-1", "sequence": { "sequence": "MSLVAEAFMNQLAAAEPWPENAALYQQLKEDQILLSDNAASLAVQAFLQMCNLPVRVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAEITHPRYGSPYPWPLNRILSYQKQWEIRRKMKAIGWAGKSLEQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLFTILTTQLITDELSEKVKNYGNLTAFCRRIEQQYFEGHDKDGSAAASARSAKRSLLR", "length": 263, "header": "tr|A0A8V1A089-1|A0A8V1A089_CHICK Computationally mapped isoform of Metaxin-2 OS=Gallus gallus OX=9031 GN=MTX2 PE=1 SV=1 CANONICAL=E1BVN1-1" }, "locus": { "chromosome": "7", "start_pos": 15863622, "end_pos": 15831171, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058988.1", "url": "https://www.ensembl.org/id/ENSGALT00010058988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035952.1", "url": "https://www.ensembl.org/id/ENSGALP00010035952.1" } ] } }, { "isoform_ac": "A0A8V1A3V2-1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1/entry#A0A8V1A3V2-1", "sequence": { "sequence": "MSLSLTPRSTRSRQQVPALELHSAEPWPENAALYQQLKEDQILLSDNAASLAVQAFLQMCNLPVRVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDDVTVEEITHPRYGSPYPWPLNRILSYQKQWEIRRKMKAIGWAGKSLEQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLFTILTTQLITDELSEKVKNYGNLTAFCRRIEQQYFEGHDKDGSAAASARSAKRSLLR", "length": 285, "header": "tr|A0A8V1A3V2-1|A0A8V1A3V2_CHICK Computationally mapped isoform of Metaxin-2 OS=Gallus gallus OX=9031 GN=MTX2 PE=1 SV=1 CANONICAL=E1BVN1-1" }, "locus": { "chromosome": "7", "start_pos": 15864071, "end_pos": 15831171, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058991.1", "url": "https://www.ensembl.org/id/ENSGALT00010058991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035955.1", "url": "https://www.ensembl.org/id/ENSGALP00010035955.1" } ] } }, { "isoform_ac": "E1BVN1-1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1/entry#E1BVN1-1", "sequence": { "sequence": "MSLVAEAFMNQLAAAEPWPENAALYQQLKEDQILLSDNAASLAVQAFLQMCNLPVRVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDDVTVEEITHPRYGSPYPWPLNRILSYQKQWEIRRKMKAIGWAGKSLEQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLFTILTTQLITDELSEKVKNYGNLTAFCRRIEQQYFEGHDKDGSAAASARSAKRSLLR", "length": 276, "header": "tr|E1BVN1-1|E1BVN1_CHICK Isoform 1 of Metaxin-2 OS=Gallus gallus OX=9031 GN=MTX2 PE=1 SV=3 CANONICAL=E1BVN1-1" }, "locus": { "chromosome": "7", "start_pos": 15863622, "end_pos": 15831171, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058997.1", "url": "https://www.ensembl.org/id/ENSGALT00010058997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035961.1", "url": "https://www.ensembl.org/id/ENSGALP00010035961.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZLV1-1", "protein_name": "Metaxin-2", "gene_name": "Mtx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAGCFVCLATEPWPENATLYQQLRGEQILLSDNAASLAVQTFLQMCNLPVKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIIQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITLARYGSPYPWPLNLILTYQKQCEVKRKMKAIGWGNKTLDQVLEDVDRCCQALSQRLGTQPYFFDKQPTELDALVFGHLYTILTTQLTSDELCEKVKNYSNLLAFCRRIEQDYFEDRGKGRLS", "length": 260 }, "evidence": [ { "id": "E1BVN1", "url": "https://omabrowser.org/oma/group/E1BVN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O64471-1", "protein_name": "Mitochondrial outer membrane import complex protein METAXIN", "gene_name": "MTX1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEGDQETNVYTLVARKPSFDLPTACPNCLPAYIYLKLAQLPFELAFNSTFPDSDELPYFESDTYVAYNNEDGGVIEKLKKDGIVNLDSQLQSLSDYLSLKALIVSWLEEALTYEIWVGTEGISTSKIYYSDLPWVISKVLFYKQTYLAKNRLGITKENAEQREKQIYKRASEAYEALSTRLGEQKFLFEDRPSSLDAFLLSHILFIIQALPVTSVLRCKLLEHSNLVRYAEKLKSEFLEASSSSPSPPLHSFPSSFPRKSSKPKSKPKVEKTEEEKKFKKRARFFLAAQFLAVVIYVSVMGGGSSDELEYEDEDD", "length": 315 }, "evidence": [ { "id": "E1BVN1", "url": "https://omabrowser.org/oma/group/E1BVN1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O75431-1", "protein_name": "Metaxin-2", "gene_name": "MTX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLVAEAFVSQIAAAEPWPENATLYQQLKGEQILLSDNAASLAVQAFLQMCNLPIKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLEEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITHARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGKKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLYTILTTQLTNDELSEKVKNYSNLLAFCRRIEQHYFEDRGKGRLS", "length": 263 }, "evidence": [ { "id": "E1BVN1", "url": "https://omabrowser.org/oma/group/E1BVN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88441-1", "protein_name": "Metaxin-2", "gene_name": "Mtx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLVAEAFVSQIAATEPWPENATLYQQLRGEQILLSDNAASLAVQAFLQMCNLPVKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITIARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGNKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLYTILTTQLTSDELSEKVKNYSNLLAFCRRIEQHYFEDWGKGRLS", "length": 263 }, "evidence": [ { "id": "E1BVN1", "url": "https://omabrowser.org/oma/group/E1BVN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2L969-1", "protein_name": "Metaxin-2", "gene_name": "MTX2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVAEAFVSQIAAAEPWPENATLYQQLKGEQILLSDNAASLAVQAFLQMCNLPIKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITHARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGNKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLYTILTTQLTNDELSEKVKNYSNLLAFCRRIEQHYFEDHSKGSSSVRLS", "length": 267 }, "evidence": [ { "id": "E1BVN1", "url": "https://omabrowser.org/oma/group/E1BVN1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9VW58-1", "protein_name": "Metaxin-2", "gene_name": "Mtx2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSQYLSQLITADKLSAEPWPEDATLYQPYEAEQILLPENASCLAVKAYLKMCNLPFLIRSCANAEHMSPGGRMTKLPFIRAGAFIFAEFEPIVNFVEQKELAIGSWQDEDEKADMRTYVSLVENIFTMAELYISFKNERVYKEVTAPRNGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVIDKVAKCCETLEYKLKESPETPFFYGDQPCELDAIAFGHLFSILTTTLPNMALAQTVQKFQHLVEFCRFVDEKYFQTRCLPN", "length": 269 }, "evidence": [ { "id": "E1BVN1", "url": "https://omabrowser.org/oma/group/E1BVN1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "SAM complex", "id": "GO:0001401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001401", "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein insertion into mitochondrial outer membrane", "id": "GO:0045040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045040", "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ], "pmid": "" }, { "name": "mitochondrial transport", "id": "GO:0006839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006839", "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ], "pmid": "" }, { "name": "mitochondrial outer membrane translocase complex assembly", "id": "GO:0070096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070096", "evidence": [ { "database": "UniProtKB", "id": "E1BVN1", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BVN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" }, { "id": "PF17171", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metaxin glutathione S-transferase", "eco_id": "ECO_0000259", "start_pos": 187, "end_pos": 249, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1BVN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVN1" }, { "id": "PF10568", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10568" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 161, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BX19-1", "uniprot_ac": "E1BX19", "uniprot_id": "E1BX19_CHICK", "mass": { "chemical_mass": 47666.0, "monoisotopic_mass": 47666.0 }, "refseq": { "ac": "NP_001264611", "name": "serine/threonine-protein kinase H1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264611" }, "gene_names": [ { "name": "PSKH1", "type": "recommended", "evidence": [ { "id": "E1BX19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ] }, { "name": "PSKH1", "type": "synonym", "evidence": [ { "id": "NP_001264611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264611" } ] }, { "name": "PSKH2", "type": "synonym", "evidence": [ { "id": "NP_001264611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264611" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase H1", "type": "recommended", "evidence": [ { "id": "E1BX19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX19/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "E1BX19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX19/entry#names_and_taxonomy" } ] }, { "name": "Protein serine kinase H1", "type": "synonym", "evidence": [ { "id": "E1BX19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX19/entry#names_and_taxonomy" } ] }, { "name": "protein serine kinase H2", "type": "synonym", "evidence": [ { "id": "NP_001264611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264611" } ] }, { "name": "serine/threonine-protein kinase H1", "type": "synonym", "evidence": [ { "id": "NP_001264611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264611" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX935768.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000247.1. On Apr 13, 2013 this sequence version replaced XP_414024.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264611", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264611" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSKH1", "url": "https://www.uniprot.org/uniprotkb/E1BX19", "locus": { "chromosome": "11", "start_pos": 1003115, "end_pos": 977031, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021951", "url": "https://www.ensembl.org/id/ENSGALG00010021951" } ] } } ], "crossref": [ { "id": "E1BX19", "url": "https://alphafold.ebi.ac.uk/entry/E1BX19", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001647", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001647", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415658", "url": "https://www.ncbi.nlm.nih.gov/gene/415658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415658", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYAGEHW", "url": "https://omabrowser.org/oma/group/SYAGEHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTK6", "url": "https://www.orthodb.org/?gene=A0A8V0ZTK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BX19", "url": "https://www.orthodb.org/?gene=E1BX19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264611", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264611", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BX19-1", "url": "https://www.uniprot.org/uniprotkb/E1BX19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPYTGHSDIYKHFIKDDGGAVIKAGSPSPPRHANPFPGNPLPAQPAQPEPRKNKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHKATKQPYAIKMIETKYREGREVCESELSVLRRVRHTNIIQLIEVFETQDRVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHTLGITHRDLKPENLLYYHPGTDSKIMITDFGLASARKKGDDCLMKTTCGTPEYIAPEILVRKPYTNSVDMWALGVISYILLSGTMPFEDDNRTRLYRQILKGKYSYSGEPWPSVSNLAKDFIDRLLTVDPSDRMTALQALKHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTKSNKSRRVRERELRELNLRYQQQYTG", "length": 420, "header": "tr|E1BX19-1|E1BX19_CHICK Isoform 1 of Serine/threonine-protein kinase H1 OS=Gallus gallus OX=9031 GN=PSKH1 PE=3 SV=1 CANONICAL=E1BX19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTK6-1", "url": "https://www.uniprot.org/uniprotkb/E1BX19/entry#A0A8V0ZTK6-1", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPYTGHSDIYKHFIKDDGGAVIKAGSPSPPRHANPFPGNPLPAQPAQPEPRKNKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHKATKQPYAIKMIETKYREGREVCESELSVLRRVRHTNIIQLIEVFETQDRVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHTLGITHRDLKPENLLYYHPGTDSKIMITDFGLASARKKGDDCLMKTTCGTPEYIAPEILVRKPYTNSVDMWALGVISYILLSGTMPFEDDNRTRLYRQILKGKYSYSGEPLKVIASYSPWLDSVGRFEDERASRRGGMPCNAFKGQRSLAQRVQPGQGLHRPPAHGGPQRQDDSPSGPEAPLGGQHGGLLLHEEPAPFHFPEPSQESLLPLPEHQVGAVHALQPLHQVQQVAPGSGTGAARAQPALPAAIHGLSTVLGPACLKSFQTSSL", "length": 476, "header": "tr|A0A8V0ZTK6-1|A0A8V0ZTK6_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=PSKH1 PE=3 SV=1 CANONICAL=E1BX19-1" }, "locus": { "chromosome": "11", "start_pos": 998792, "end_pos": 979785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053359.1", "url": "https://www.ensembl.org/id/ENSGALT00010053359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032161.1", "url": "https://www.ensembl.org/id/ENSGALP00010032161.1" } ] } }, { "isoform_ac": "E1BX19-1", "url": "https://www.uniprot.org/uniprotkb/E1BX19/entry#E1BX19-1", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPYTGHSDIYKHFIKDDGGAVIKAGSPSPPRHANPFPGNPLPAQPAQPEPRKNKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHKATKQPYAIKMIETKYREGREVCESELSVLRRVRHTNIIQLIEVFETQDRVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHTLGITHRDLKPENLLYYHPGTDSKIMITDFGLASARKKGDDCLMKTTCGTPEYIAPEILVRKPYTNSVDMWALGVISYILLSGTMPFEDDNRTRLYRQILKGKYSYSGEPWPSVSNLAKDFIDRLLTVDPSDRMTALQALKHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTKSNKSRRVRERELRELNLRYQQQYTG", "length": 420, "header": "tr|E1BX19-1|E1BX19_CHICK Isoform 1 of Serine/threonine-protein kinase H1 OS=Gallus gallus OX=9031 GN=PSKH1 PE=3 SV=1 CANONICAL=E1BX19-1" }, "locus": { "chromosome": "11", "start_pos": 998739, "end_pos": 979785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053367.1", "url": "https://www.ensembl.org/id/ENSGALT00010053367.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032168.1", "url": "https://www.ensembl.org/id/ENSGALP00010032168.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415658", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABY1-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "Pskh1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSATKNDVYKHFITEVDSVGPLKAGFPATSQYAPPCPGAPTTGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "E1BX19", "url": "https://omabrowser.org/oma/group/E1BX19/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HKX0-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "Pskh1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGAKNDVYKHFITEVDSVGPLKAGFPATSQYAPPYPGVPTTGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "E1BX19", "url": "https://omabrowser.org/oma/group/E1BX19/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P11801-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "PSKH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "E1BX19", "url": "https://omabrowser.org/oma/group/E1BX19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0V7M1-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "PSKH1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPLKGGFPAASQGANPSPGTPRTSHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "E1BX19", "url": "https://omabrowser.org/oma/group/E1BX19/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q501V0-1", "protein_name": "Serine/threonine-protein kinase H1 homolog", "gene_name": "pskh1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCRTSKVLPEPPGDVQLDLVKKVEPHQTDVYKNFIKYDGGGEKTGSPSPQGQSQAVAKVSQSPPPANDQPEPADSHRKKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGREVCESELCVLRRVRHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGITHRDLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKPYTNAVDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQALKHPWIVSMAASSSMKNLHRSISQNLLKRASSRCHSTKSSQSTRSSRSTKSSKARRLREKELRELNRRYQQQCNG", "length": 422 }, "evidence": [ { "id": "E1BX19", "url": "https://omabrowser.org/oma/group/E1BX19/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91YA2-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "Pskh1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKNDVYKHFITEVDSVGPLKAGFPATSQYAPPCPGVPNTGHTAPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "E1BX19", "url": "https://omabrowser.org/oma/group/E1BX19/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1BX19", "url": "https://www.uniprot.org/uniprotkb/E1BX19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BX19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX19" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 351, "start_aa": "Tyr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 297, "end_pos": 299 }, { "start_pos": 397, "end_pos": 399 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BRU0-1", "uniprot_ac": "E1BRU0", "uniprot_id": "E1BRU0_CHICK", "mass": { "chemical_mass": 83928.0, "monoisotopic_mass": 83928.0 }, "refseq": { "ac": "XP_004945193", "name": "mitotic spindle assembly checkpoint protein MAD1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945193" }, "gene_names": [ { "name": "MAD1L1", "type": "recommended", "evidence": [ { "id": "E1BRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ] }, { "name": "MAD1L1", "type": "synonym", "evidence": [ { "id": "XP_004945193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945193" } ] } ], "protein_names": [ { "name": "Mitotic spindle assembly checkpoint protein MAD1", "type": "recommended", "evidence": [ { "id": "E1BRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRU0/entry#names_and_taxonomy" } ] }, { "name": "Mitotic arrest deficient 1-like protein 1", "type": "synonym", "evidence": [ { "id": "E1BRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRU0/entry#names_and_taxonomy" } ] }, { "name": "mitotic spindle assembly checkpoint protein MAD1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945193" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945193" } ] }, { "annotation": "Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Forms a heterotetrameric complex with the closed conformation form of MAD2L1 (C-MAD2) at unattached kinetochores during prometaphase, recruits an open conformation of MAD2L1 (O-MAD2) and promotes the conversion of O-MAD2 to C-MAD2, which ensures mitotic checkpoint signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z8#function" }, { "database": "UniProtKB", "id": "ARBA00053509", "url": "https://www.uniprot.org/uniprotkb/ARBA00053509#function" }, { "database": "UniProtKB", "id": "A0A8V0Z508", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z508#function" }, { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZC99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC99#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAD1L1", "url": "https://www.uniprot.org/uniprotkb/E1BRU0", "locus": { "chromosome": "14", "start_pos": 2760330, "end_pos": 3080371, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019848", "url": "https://www.ensembl.org/id/ENSGALG00010019848" } ] } } ], "crossref": [ { "id": "E1BRU0", "url": "https://alphafold.ebi.ac.uk/entry/E1BRU0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004224", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004224", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427658", "url": "https://www.ncbi.nlm.nih.gov/gene/427658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427658", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKLDFMP", "url": "https://omabrowser.org/oma/group/YKLDFMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Z8", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z508", "url": "https://www.orthodb.org/?gene=A0A8V0Z508", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAT9", "url": "https://www.orthodb.org/?gene=A0A8V0ZAT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC99", "url": "https://www.orthodb.org/?gene=A0A8V0ZC99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BRU0", "url": "https://www.orthodb.org/?gene=E1BRU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23168:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23168:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1BRU0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1BRU0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945193", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z508", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z508", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z508-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z508-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BRU0-1", "url": "https://www.uniprot.org/uniprotkb/E1BRU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDLEDNTTVFSTLRSFNNFISQRMEGVSGQAVPASSQSSLQIQYQQRVQLEEQAGQIHSKSQLLQMEREKMQMELSHKRARIELEKAANTNARNYEREADRNQELLTRIKQYQERETEAENKLKEQMEMNKSYKKSMETMSKKLQEKESKLAEANETITILKGKISELQWNIMNQEMQMTSQDSQKQELMEQLDVQHKKWQEATQQIQTLQASQSLLAEYEQKIKDLEQKFSQQEHDAVIVKNMKTELARFPKMERELRQLREENAYFREMKENNGLLKEEVEGLQRKLERYEKVQAQLVTAELENEKLLGKLKSWEKLDQSTGLNIRTPDDLSRQIVALQQRELALKEQNSTITNSARIMEKARQQLQEEILQIQSQLLDEKKKREQHEALVRRLQKRVLLLTKERDGMRAILESYDSELTPAEHSPQLNRRMREAEEMVQKLHAHNAELEVQMSQVLEEVGNQKQRAEMLEVEMKVLKSRECTAEQSAFITKEEVDTLRLKIEELEAERSKLEEQNRSLEMKLEKLTMQGDYDPSKTKVLHFSMNPASLAKQQRKEEQQQLQEECERLRELVRVLEAGGSVHGNLEGVGSFQSPQEVAELKKQVESAELKNQRLKEIFQTKIQEFRKVCYTLTGYQIDITTENQYRLTSIYAEHQGDCLLFKASSSSGGKMQLLENEFSRTVRELIELHLLHQDSIPAFLSALTLELFSRQTIA", "length": 717, "header": "tr|E1BRU0-1|E1BRU0_CHICK Isoform 1 of Mitotic spindle assembly checkpoint protein MAD1 OS=Gallus gallus OX=9031 GN=MAD1L1 PE=1 SV=4 CANONICAL=E1BRU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4Z8-1", "url": "https://www.uniprot.org/uniprotkb/E1BRU0/entry#A0A8V0Z4Z8-1", "sequence": { "sequence": "MTSNAITDPVAFPPRSDKPSRISLCCYGAYLAWLEVEMKVLKSRECTAEQSAFITKEEVDTLRLKIEELEAERSKLEEQNRSLEMKLEKLTMQGDYDPSKTKVLHFSMNPASLAKQQRKEEQQQLQEECERLRELVRVLEAGGSVHGNLEGVGSFQSPQEVAELKKQVESAELKNQRLKEIFQTKIQEFRKVCYTLTGYQIDITTENQYRLTSIYAEHQGDCLLFKASSSSGGKMQLLENEFSRTVRELIELHLLHQDSIPAFLSALTLELFSRQTIA", "length": 278, "header": "tr|A0A8V0Z4Z8-1|A0A8V0Z4Z8_CHICK Computationally mapped isoform of Mitotic spindle assembly checkpoint protein MAD1 OS=Gallus gallus OX=9031 GN=MAD1L1 PE=3 SV=1 CANONICAL=E1BRU0-1" }, "locus": { "chromosome": "14", "start_pos": 2916298, "end_pos": 2761218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047929.1", "url": "https://www.ensembl.org/id/ENSGALT00010047929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028309.1", "url": "https://www.ensembl.org/id/ENSGALP00010028309.1" } ] } }, { "isoform_ac": "A0A8V0Z508-1", "url": "https://www.uniprot.org/uniprotkb/E1BRU0/entry#A0A8V0Z508-1", "sequence": { "sequence": "MEDLEDNTTVFSTLRSFNNFISQRMEGVSGQAVPASSQSSLQIQYQQRVQLEEQAGQIHSKSQLLQMEREKMQMELSHKRARIELEKAANTNARNYETITILKGKISELQWNIMNQEMQMTSQDSQKQELMEQLDVQHKKWQEATQQIQTLQASQSLLAEYEQKIKDLEQKFSQQEHDAVIVKNMKTELARFPKMERELRQLREENAYFREMKENNGLLKEEVEGLQRKLERYEKVQAQLVTAELENEKLLGKLKSWEKLDQSTGLNIRTPDDLSRQIVALQQRELALKEQNSTITNSARIMEKARQQLQEEILQIQSQLLDEKKKREQHEALVRRLQKRVLLLTKERDGMRAILESYDSELTPAEHSPQLNRRMREAEEMVQKLHAHNAELEVQMSQVLEEVGNQKQRAEMLEVEMKVLKSRECTAEQSAFITKEEVDTLRLKIEELEAERSKLEEQNRSLEMKLEKLTMQGDYDPSKTKVLHFSMNPASLAKQQRKEEQQQLQEECERLRELVRVLEAGGSVHGNLEGVGSFQSPQEVAELKKQVESAELKNQRLKEIFQTKIQEFRKVCYTLTGYQIDITTENQYRLTSIYAEHQGDCLLFKASSSSGGKMQLLENEFSRTVRELIELHLLHQDSIPAFLSALTLELFSRQTIA", "length": 657, "header": "tr|A0A8V0Z508-1|A0A8V0Z508_CHICK Computationally mapped isoform of Mitotic spindle assembly checkpoint protein MAD1 OS=Gallus gallus OX=9031 GN=MAD1L1 PE=1 SV=1 CANONICAL=E1BRU0-1" }, "locus": { "chromosome": "14", "start_pos": 3078330, "end_pos": 2761218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047965.1", "url": "https://www.ensembl.org/id/ENSGALT00010047965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028319.1", "url": "https://www.ensembl.org/id/ENSGALP00010028319.1" } ] } }, { "isoform_ac": "A0A8V0ZAT9-1", "url": "https://www.uniprot.org/uniprotkb/E1BRU0/entry#A0A8V0ZAT9-1", "sequence": { "sequence": "MEDLEDNTTVFSTLRSFNNFISQRMEGVSGQAVPASSQSSLQIQYQQRVQLEEQAGQIHSKSQLLQMEREKMQMELSHKRARIELEKAANTNARNYEREADRNQELLTRIKQYQERETEAENKLKEQMEMNKSYKKSMETMSKKLQEKESKLAEANETITILKGKISELQWNIMNQEMQMTSQDSQKQELMEQLDVQHKKWQEATQQIQTLQASQSLLAEYEQKIKDLEQKFSQQEHDAVIVKNMKTELARFPKMERELRQLREENAYFREMKENNGLLKEEVEGLQRKLERYEKVQAQLVTAELENEKLLGKLKSWEKLDQSTGLNIRTPDDLSRQIVALQQRELALKEQNSTITNSARIMEKARQQLQEEILQIQSQLLDEKKKREQHEALVRRLQKRVLLLTKERDGMRAILESYDSELTPAEHSPQLNRRMREAEEMVQKLHAHNAELEVQMSQVLEEVGNQKQRAEMLEVEMKVLKSRECTAEQSAFITKEEVDTLRLKIEELEAERSKLEEQNRSLEMKLEKLTMQGDYDPSKTKVLHFSMNPASLAKQQRKEEQQQLQEECERLRELVRVLEAGGSVHGNLEGVGSFQSPQEVAELKKQVESAELKNQRLKEIFQTKIQEFRKVCYTLTGYQIDITTENQYRLTSIYAEHQGDCLLFKQVNLSQDDTQRR", "length": 677, "header": "tr|A0A8V0ZAT9-1|A0A8V0ZAT9_CHICK Computationally mapped isoform of Mitotic arrest deficient 1 like 1 OS=Gallus gallus OX=9031 GN=MAD1L1 PE=1 SV=1 CANONICAL=E1BRU0-1" }, "locus": { "chromosome": "14", "start_pos": 3078330, "end_pos": 2824391, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047939.1", "url": "https://www.ensembl.org/id/ENSGALT00010047939.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028311.1", "url": "https://www.ensembl.org/id/ENSGALP00010028311.1" } ] } }, { "isoform_ac": "A0A8V0ZC99-1", "url": "https://www.uniprot.org/uniprotkb/E1BRU0/entry#A0A8V0ZC99-1", "sequence": { "sequence": "MGASSREISAAGRGGRSKRGSGAMEDLEDNTTVFSTLRSFNNFISQRMEGVSGQAVPASSQSSLQIQYQQRVQLEEQAGQIHSKSQLLQMEREKMQMELSHKRARIELEKAANTNARNYEREADRNQELLTRIKQYQERETEAENKLKEQMEMNKSYKKSMETMSKKLQEKESKLAEANETITILKGKISELQWNIMNQEMQMTSQDSQKQELMEQLDVQHKKWQEATQQIQTLQASQSLLAEYEQKIKDLEQKFSQQEHDAVIVKNMKTELARFPKMERELRQLREENAYFREMKENNGLLKEEVEGLQRKLERYEKVQAQLVTAELENEKLLGKLKSWEKLDQSTGLNIRTPDDLSRQIVALQQRELALKEQNSTITNSARIMEKARQQLQEEILQIQSQLLDEKKKREQHEALVRRLQKRVLLLTKERDGMRAILESYDSELTPAEHSPQLNRRMREAEEMVQKLHAHNAELEVQMSQVLEEVGNQKQRAEMLEVEMKVLKSRECTAEQSAFITKEEVDTLRLKIEELEAERSKLEEQNRSLEMKLEKLTMQGDYDPSKTKVLHFSMNPASLAKQQRKEEQQQLQEECERLRELVRVLEAGGSVHGNLEGVGSFQSPQEVAELKKQVESAELKNQRLKEIFQTKIQEFRKVCYTLTGYQIDITTENQYRLTSIYAEHQGDCLLFKASSSSGGKMQLLENEFSRTVRELIELHLLHQDSIPAFLSALTLELFSRQTIA", "length": 740, "header": "tr|A0A8V0ZC99-1|A0A8V0ZC99_CHICK Computationally mapped isoform of Mitotic spindle assembly checkpoint protein MAD1 OS=Gallus gallus OX=9031 GN=MAD1L1 PE=1 SV=1 CANONICAL=E1BRU0-1" }, "locus": { "chromosome": "14", "start_pos": 3079975, "end_pos": 2761218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047947.1", "url": "https://www.ensembl.org/id/ENSGALT00010047947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028312.1", "url": "https://www.ensembl.org/id/ENSGALP00010028312.1" } ] } }, { "isoform_ac": "E1BRU0-1", "url": "https://www.uniprot.org/uniprotkb/E1BRU0/entry#E1BRU0-1", "sequence": { "sequence": "MEDLEDNTTVFSTLRSFNNFISQRMEGVSGQAVPASSQSSLQIQYQQRVQLEEQAGQIHSKSQLLQMEREKMQMELSHKRARIELEKAANTNARNYEREADRNQELLTRIKQYQERETEAENKLKEQMEMNKSYKKSMETMSKKLQEKESKLAEANETITILKGKISELQWNIMNQEMQMTSQDSQKQELMEQLDVQHKKWQEATQQIQTLQASQSLLAEYEQKIKDLEQKFSQQEHDAVIVKNMKTELARFPKMERELRQLREENAYFREMKENNGLLKEEVEGLQRKLERYEKVQAQLVTAELENEKLLGKLKSWEKLDQSTGLNIRTPDDLSRQIVALQQRELALKEQNSTITNSARIMEKARQQLQEEILQIQSQLLDEKKKREQHEALVRRLQKRVLLLTKERDGMRAILESYDSELTPAEHSPQLNRRMREAEEMVQKLHAHNAELEVQMSQVLEEVGNQKQRAEMLEVEMKVLKSRECTAEQSAFITKEEVDTLRLKIEELEAERSKLEEQNRSLEMKLEKLTMQGDYDPSKTKVLHFSMNPASLAKQQRKEEQQQLQEECERLRELVRVLEAGGSVHGNLEGVGSFQSPQEVAELKKQVESAELKNQRLKEIFQTKIQEFRKVCYTLTGYQIDITTENQYRLTSIYAEHQGDCLLFKASSSSGGKMQLLENEFSRTVRELIELHLLHQDSIPAFLSALTLELFSRQTIA", "length": 717, "header": "tr|E1BRU0-1|E1BRU0_CHICK Isoform 1 of Mitotic spindle assembly checkpoint protein MAD1 OS=Gallus gallus OX=9031 GN=MAD1L1 PE=1 SV=4 CANONICAL=E1BRU0-1" }, "locus": { "chromosome": "14", "start_pos": 3078330, "end_pos": 2761218, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047956.1", "url": "https://www.ensembl.org/id/ENSGALT00010047956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028315.1", "url": "https://www.ensembl.org/id/ENSGALP00010028315.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427658", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" }, { "id": "R-GGA-5663220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "resource": "Reactome", "description": "RHO GTPases Activate Formins" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A1B8-1", "protein_name": "Mitotic arrest deficient 1 like 1", "gene_name": "MAD1L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDLGENTTVLSTLRSLNSFISQRVEGGSGLDVSTPAQGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARSYEREVDRNQELLTRIRQLQEREAEAEEKMKEQLERYRLCQQSLDAASRKLREEEDSLAEAGETISALKGRLSELQWSAMNQEMQVKRLESEKQELKEQLDLQHKKWQEAQQKVQELQASQDARADQEQRIKDLEQKLSLQEQDAAIVRSMRSELVRLPTMERELRQLREENACLRETREASGLLREELEGLQRRLGRQEKLQENLVNLELENERLLTKLQSWERLGQTTGLSIRTPEELSSFIVELQQRELTLKDRNSTLTSSARGLEKARLQLQEEVRQVSSQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYAPQLTRRLREAEDMVQKVHAHSSEVEVQLSQALEELGGQKQRADALEMELQMLKSQAGPAEQSFLFSREEVSALRLKIEELAQERSRLEEDKKLLEAQLERLTLQGDFDQSRTKVLHLSLNPASVARQRFREDWQQLQEECKHLRELVRALEAGGPVPADLEAAAGLPSSKEVAELKRQVESAELKNQRLKEVFQTKIQEFRKACYALTGYQVDITTEGQFRLTSMYAERKADCLVFKAAGPSGTKMQPPDRGLARPRARRPSGGAASDSARGGPLSPAPAQDPRAGPPWPVGSCCERRPRPGPWLRPTLRGRATTPHPPSGRQA", "length": 752 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A596-1", "protein_name": "Mitotic spindle assembly checkpoint protein MAD1", "gene_name": "Mad1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRSCPLPSGMHTVRVDPVARLPFAGSSVSCSRGRCGPPCPVAGRGRVTMEDLGENTTVLSTLRSLNNFISQRMEGASGLDVSTSASGSLQKQYEQNMQLEERAEQIRSKSYLIQVEREKMQMELSHKRARVELERAASTNARNYEREVDRNQELLARIRQLQEREAAAEEKMREQLERHRLCKQSLDAASQQLREREDGLAAARETISSLKGRVSELQLSAMDQKVQVKRLESEKQELKEQLELQQRKWQEANQKIQELQASQEERTDQEQKIKDLEQKLCLQEQDAAVVKSMKSELLRLPRMERELKRLREENTHLREMRETNGLLTEELEGLQRKLGRQEKMQEALVDLELEKEKLLAKLQSWEKLDQTMGLNLRTPEDLSRFVIELQQRELALKEKNSSITSSARGLEKAQQQLQDEVRQVNAQLLEERKKRETHEALARRLQKRNALLTKERDGMRAILGSYDSELTQAEYSPQLTQRMWEAEDMVQKVHAHSSEMEAQLSQALEELGVQKQRADTLEMELKMLRAQTSSAEASFPFCKEEVDALRLKVEELEGERSRLEQEKQALEMQMERLTLQGDYNQSRTKVLHMSLNPASMARQRQREDHDRLQEECERLRGLVHALERGGPIPADLEAASSLPSSKEVAELRKQVESAELKNQRLKEVFQTKIQEFRKVCYTLTGYQIDVTTESQYRLTSRYAEHQTDCLIFKATGPSGSKMQLLETEFSRSVPELIELHLLQQDSIPAFLSALTIELFSRQTSV", "length": 766 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40957-1", "protein_name": "Spindle assembly checkpoint component MAD1", "gene_name": "MAD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDVRAALQCFFSALSGRFTGKKLGLEIYSIQYKMSNSGGSSPFLESPGGSPDVGSTNGQSNRQIQALQFKLNTLQNEYEIEKLQLQKQTNILEKKYKATIDELEKALNDTKYLYESNDKLEQELKSLKERSANSMNDKDKCIEELRTTLQNKDLEMETLRQQYDSKLSKVTNQCDHFKLEAESSHSLLMKYEKEIKRQSVDIKDLQHQVMEKDDELSSVKASKMINSHPNYSTEEFNELTEMNKMIQDQVQYTKELELANMQQANELKKLKQSQDTSTFWKLENEKLQNKLSQLHVLESQYENLQLENIDLKSKLTKWEIYNDSDDDDDNNVNNNDNNNNNKNDNNNDNNNDTSNNNNINNNNRTKNNIRNNPEEIIRDWKLTKKECLILTDMNDKLRLDNNNLKLLNDEMALERNQILDLNKNYENNIVNLKRLNHELEQQKSLSFEECRLLREQLDGLYSAQNNALLEVENSETHASNKNVNEDMNNLIDTYKNKTEDLTNELKKLNDQLLSNSNDVETQRKKRKLTSDQIGLNYSQRLNELQLENVSVSRELSKAQTTIQLLQEKLEKLTKLKEKKIRILQLRDGPFIKDQFIKKNKLLLLEKENADLLNELKKNNPAVETVPISVYDSLNFELKQFEQEVFKSNKRFSRLKQVFNNKSLEFIDVVNSLLGFKLEFQQDSRVKIFSCFKPEKYLIADLNENTLKSNLDADIEGWDDLMNLWVEDRGQLPCFLATITLRLWEQRQAK", "length": 749 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54JX0-1", "protein_name": "Mitotic spindle assembly checkpoint protein 1", "gene_name": "mad1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQEDDDNILLSTSTLLKSQDTFRGKINTNSSLYKSLNSNNNNFNFNQSINNNNNNNNNNNKAIFLDNKEFNSLSKDIEEYLNSIENNNSDNDDDDDDDEQNSTVNEINNDLPITFLSDANEAIKKQQLYIQQLERQLKQDKRIGDNLLQQSLELSSTEKELSELKVKFNDIERTNKFLLTKTAEARLDLENSEKINQTKIANKNLEIEGLSKKIKFLSNSEKELEDKLKEMDNKYLELERNTQLKIRAIEKEKTNCRTEIVELKHKNSNQNDLTSIQKLKDSEIQHLKSINKKLEEQINHQKQTLDSTLKQLSEKDKQLDTFKNIITSPPPPSSSSSSLSSASASLKNSEIETLNQSLKSEINYFKKINKEQKDEINRLNKIFEGVGNLEMIKQQNENMKEKIKRLEPLIEKYNRLQVEHNQLINEKNQMELTFGSIDKQQSTQQLQQKIIQLENDNQTLIGKIGEITANWKLMESRNQDYSIRIQQEKDSLNEKLTKINELTEKIKRLEKLNYLLNRERDNIKNILDTYDDNQQPQQLQDDDNNNNNNNNNNNNESGDTKRRIEIINELERSLKEKNILIQEYEYKLDCNNNSNNVNGDFSSINYKEECKRLNKEIEKLLQENALLEARLGKGEFDPLKTKVLHFSNNPSSLILNQQQQQEESNNNNINNNINNDKNNNNSIQIDKKLIEENHRLLIQINDGEKKMDRLKQIFKQKINEFREAVYALLGFKIDVDTNNRYKLQSMYAERESDFLMFQQSPPTQQSNNKGRIQMELLETEFTRNLDKEIKAYLFACKSIPSFLSQVTIELFSKQTFHP", "length": 819 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q80YF0-1", "protein_name": "Mitotic spindle assembly checkpoint protein MAD1", "gene_name": "MAD1L1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDLGENTTVLSTLRSLNNFISQRVEGGSGLDVSTAAPGSLQLQYEQSMQLEERAEQIRSKSYLIQMEREKMQMELSHKRARVELERAANTSARNYEREVDRNQELLARIRQLQEREAAAEEKMQEQLERHRLCKQSLDAASQQLREREDGLAAARETISSLKGRVSEMQLNAMDQKVQVKRLESEKQELKEQLELQQRKCQEASQKIQELQASQEERADHEQKIKDLEQKLCLQEQDAAVVKNMKSELLRLPRMERELKRLREENTHLREMKETNGLLTEELEGLQRKLGRQEKMQEALVDLELEKEKLLAKLQSWEKLDQTMGVNLRTPEDLSRFVVELQQRELTLKEKNNTITSSARGLEKAQQQLQDEVRQVSAQLLEERKKREIHEALARRLQKRIVLLTKERDGMRAILGSYDSELTQAEYSAQLTQRMWEAEDMVQKVHAHSSEMETQLSQALEELGVQKQRADTLEMELKMLRAQTSSAETSFPFCKEEVDALRLKVEELEGERSRLEQEKQALEMQMERLTLQGDYNQSRTKVLHMSLNPASMARKRQQEDHARLQGECERLRGLVHALERGGPIPADLEVASSLPSSKEVAELRKQVESAELKNQRLKEVFQTKIQEFRKVCYTLTGYQIDVTTENQYRLTSRYAEHQSDCLIFKATGPSGSKMQLLETEFSRSVPELIELHLLQQDSIPAFLSALTIELFSRQTSI", "length": 717 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9LTY1-1", "protein_name": "Mitotic spindle checkpoint protein MAD1", "gene_name": "MAD1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MILRTPQPKRLRSDAGESPFPTGATGSGNQLIIYEDSPLPAPAPLQTSHDHSADQHLCTYQCRQMVKADVLDALSTAEKQVEESKTKLQTLNANFTEADAERKHFRDKFLYSEQELAAAKAREKMLQEQLLMEINNSQERYTKELQSCHELEVKLQNEMNLRKKAESSAATAEEKAKLLEDKLTQLSGSVDREKKRLNNDIAQLGKEAKLSVARIGADLERMQCRAQNAETESNLLRSQLEHLKLIFDECLQEKTEVDKKLSSFTSEAASSSDNSVLVKHLQEELKRYEAEVREARKLKSRHLDAELLNVNLLEEQSRRERAESELSKFHDLQLSMEKLENELSSWKSLLNDIPGVSCPDDIVMRFSVLQNEVVQSTMKIGEASTRIKQLEETLEAIQLGRQNAVSEAALAKEKSEALKTDVKRIEVMLTLVTEEKEQLKAVVNELRKSNSEGSVSGAADGALIQGFESSLAKKENYIKDLEQDLNQLKDVNNRQRTEIELLNEKLVDEARRNKSLERDSDRLRSEISLLESKLGHGDYSAANTRVLRMVNTLGVENEAKQTIEALQAELQKTKERLQAVEELKSQSGDAGKLVDSHITGKIAQLKEQNATLEKREERYKTVFADRISVFRRACCELFGYKIVMDEHQRPNGIPVTRFTLQSIYAQSDDEKLEFEYESGNTSILNNEYASQGDIAKQIEIFIRKFNSIPAFTANLTMESFNRRTLY", "length": 726 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WTX8-1", "protein_name": "Mitotic spindle assembly checkpoint protein MAD1", "gene_name": "Mad1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDLGENTTVLSSLRSLNNFISQRMEGTSGLDVSTSASGSLQKQYEYHMQLEERAEQIRSKSYLIQVEREKMQMELSHKRARVELERAASTNARNYEREVDRNQELLARIRQLQECEATAEEKMREQLERHRLCKQNLDAVSQQLREQEDSLASAREMISSLKGRVSELQLSAMDQKVQVKRLESEKQELKEQLELQQRKWQEANQKIQELQASQDERAEHEQKIKDLEQKLCLQEQDAAVVKSMKSELMRMPRMERELKRLHEENTHLREMKETNGLLTEELEGLQRKLSRQEKMQEALVDLELEKEKLLAKLQSWENLDQTMGLNLRTPEDLSRFVVELQQRELTLKEKNNSITSSARGLEKVQQQLQDEVRQANAQLLEERKKRETHEALARRLQKRNALLTKERDGMRAILGSYDSELTQTEYSTQLTQRLWEAEDMVQKVHAHSSEMEAQLSQALEELGVQKQRADTLEMELKMLKAQTSSAESSFSFCKEEVDALRLKVEELEGERSRLEQEKQVLEMQMEKLTLQGDYNQSRTKVLHMSLNPISMARQRQHEDHDRLQEECERLRGLVHALERGGPIPADLEAASSLPSSKEVAELRKQVESAELKNQRLKEVFQTKIQEFRKVCYTLTGYQIDVTTESQYRLTSRYAEHQTDCLIFKATGPSGSKMQLLETEFSRSVPELIELHLLQQDSIPAFLSALTIELFSRQTSI", "length": 717 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6D9-1", "protein_name": "Mitotic spindle assembly checkpoint protein MAD1", "gene_name": "MAD1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA", "length": 718 }, "evidence": [ { "id": "E1BRU0", "url": "https://omabrowser.org/oma/group/E1BRU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 12, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "nuclear pore nuclear basket", "id": "GO:0044615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044615", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "mitotic spindle pole", "id": "GO:0097431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097431", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "MAD1 complex", "id": "GO:1990706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990706", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint MAD1-MAD2 complex", "id": "GO:1990728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990728", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "attachment of mitotic spindle microtubules to kinetochore", "id": "GO:0051315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051315", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "regulation of metaphase plate congression", "id": "GO:0090235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090235", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090267", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "kinetochore binding", "id": "GO:0043515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043515", "evidence": [ { "database": "UniProtKB", "id": "E1BRU0", "url": "https://www.uniprot.org/uniprotkb/E1BRU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BT20-1", "uniprot_ac": "E1BT20", "uniprot_id": "E1BT20_CHICK", "mass": { "chemical_mass": 40424.0, "monoisotopic_mass": 40424.0 }, "refseq": { "ac": "NP_001264366", "name": "pleckstrin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264366" }, "gene_names": [ { "name": "PLEK2", "type": "recommended", "evidence": [ { "id": "E1BT20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT20" } ] }, { "name": "PLEK2", "type": "synonym", "evidence": [ { "id": "NP_001264366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264366" } ] } ], "protein_names": [ { "name": "Pleckstrin-2", "type": "recommended", "evidence": [ { "id": "E1BT20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BT20/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin-2", "type": "synonym", "evidence": [ { "id": "NP_001264366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264366" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01014529.1, BX933144.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Apr 7, 2013 this sequence version replaced XP_421197.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264366", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264366" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BT20", "url": "https://www.uniprot.org/uniprotkb/E1BT20" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEK2", "url": "https://www.uniprot.org/uniprotkb/E1BT20", "locus": { "chromosome": "5", "start_pos": 28463326, "end_pos": 28475670, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019998", "url": "https://www.ensembl.org/id/ENSGALG00010019998" } ] } } ], "crossref": [ { "id": "E1BT20", "url": "https://alphafold.ebi.ac.uk/entry/E1BT20", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009562", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009562", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04444", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04444", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423278", "url": "https://www.ncbi.nlm.nih.gov/gene/423278", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037369", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037369", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423278", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423278", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VVRNWKV", "url": "https://omabrowser.org/oma/group/VVRNWKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZBA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCR2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIS2", "url": "https://www.orthodb.org/?gene=A0A8V0ZIS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BT20", "url": "https://www.orthodb.org/?gene=E1BT20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12092", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12092", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12092:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12092:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264366", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT20", "url": "https://www.uniprot.org/uniprotkb/E1BT20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BT20-1", "url": "https://www.uniprot.org/uniprotkb/E1BT20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEETTGVLKEGFLVKRGHIVHNWKVRWFVLLQDKLLYYKLEGGKKESSPKGRILLDGCTITCPCLEYENRPLLIKLKTKTNTDYFLECCSREERDSWALDITGAIHAGHPVQVQELHRMKNSFKLLENISLHHIVDKMRDSSTGIKLTLNVEQGNRYKETFTGSALVDWLISNSFAVSRFEAVTLASMLMEENFTKPVGARSTGATRYSDLSEQFLDDSTALYMFAETSKKMLSSKEELQFNISELSGTIVKQGYLVKQGHKRKNWKVRKFVLRADPAFLHYYDPTKEENRPVGGFSLRGCLVSALEDNGVPAGVKGNVQGNLFKIITKKDIHYYIQASSKAERTQWIEAIKPLT", "length": 355, "header": "tr|E1BT20-1|E1BT20_CHICK Isoform 1 of Pleckstrin-2 OS=Gallus gallus OX=9031 GN=PLEK2 PE=4 SV=3 CANONICAL=E1BT20-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBA3-1", "url": "https://www.uniprot.org/uniprotkb/E1BT20/entry#A0A8V0ZBA3-1", "sequence": { "sequence": "MSSPQLRACRGTGCQGLGAPQQDEDLLSVGRDGRDHRSPEGGLPRQAGNSSTGSVSAQEAEVGSLSSNMKGCKEKGHIVHNWKVRWFVLLQDKLLYYKLEGGKKESSPKGRILLDGCTITCPCLEYENRPLLIKLKTKTNTDYFLECCSREERDSWALDITGAIHAGHPVQVQELHRMKNSFKLLENISLHHIVDKMRDSSTGIKLTLNVEQGNRYKETFTGSALVDWLISNSFAVSRFEAVTLASMLMEENFTKPVGARSTGATRYSDLSEQFLDDSTALYMFAETSKKMLSSKEELQFNISELSGTIVKQGYLVKQGHKRKNWKVRKFVLRADPAFLHYYDPTKEENRPVGGFSLRGCLVSALEDNGVPAGVKGNVQGNLFKIITKKDIHYYIQASSKAERTQWIEAIKPLT", "length": 414, "header": "tr|A0A8V0ZBA3-1|A0A8V0ZBA3_CHICK Computationally mapped isoform of Pleckstrin-2 OS=Gallus gallus OX=9031 GN=PLEK2 PE=4 SV=1 CANONICAL=E1BT20-1" }, "locus": { "chromosome": "5", "start_pos": 28471782, "end_pos": 28463883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048284.1", "url": "https://www.ensembl.org/id/ENSGALT00010048284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028469.1", "url": "https://www.ensembl.org/id/ENSGALP00010028469.1" } ] } }, { "isoform_ac": "A0A8V0ZCR2-1", "url": "https://www.uniprot.org/uniprotkb/E1BT20/entry#A0A8V0ZCR2-1", "sequence": { "sequence": "MEETTGVLKEGFLVKRGHIVHNWKVRWFVLLQDKLLYYKLEGGKKESSPKGRILLDGCTITCPCLEYENRPLLIKLKTKTNTDYFLECCSREERDSWALDITGAIHAGHPVQVQELHRMKNSFKLLENISLHHIVDKMRDSSTGIKLTLNVEQGNRYKETFTGSALVDWLISNSFAVSRFEAVTLASMLMEENFTKPVGARSTGATRYSDLSEQFLDDSTALYMFAETSKKMLSSKEELQFNISELSGTIVKQGYLVKQGHKRKNWKVRKFVLRADPAFLHYYDPTKVCERGVDTPRNPLADLNIIMKIQGNYVVNVPLSQISFC", "length": 325, "header": "tr|A0A8V0ZCR2-1|A0A8V0ZCR2_CHICK Computationally mapped isoform of Pleckstrin 2 OS=Gallus gallus OX=9031 GN=PLEK2 PE=4 SV=1 CANONICAL=E1BT20-1" }, "locus": { "chromosome": "5", "start_pos": 28471688, "end_pos": 28465247, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048294.1", "url": "https://www.ensembl.org/id/ENSGALT00010048294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028475.1", "url": "https://www.ensembl.org/id/ENSGALP00010028475.1" } ] } }, { "isoform_ac": "A0A8V0ZIS2-1", "url": "https://www.uniprot.org/uniprotkb/E1BT20/entry#A0A8V0ZIS2-1", "sequence": { "sequence": "MEETTGVLKEGFLVKRGHIVHNWKVRWFVLLQDKLLYYKLEGGKKESSPKGRILLDGCTITCPCLEYENRPLLIKLKTKTNTDYFLECCSREERDSWALDITGAIHAGHPVQVQELHRMKNSFKLLENISLHHIVDKMRDSSTGIKLTLNVEQGNRYKETFTGSALVDWLISNSFAVSRFEAVTLASMLMEENFTKPVGARSTGATRYSDLSEQFLDDSTALYMFGHKRKNWKVRKFVLRADPAFLHYYDPTKEENRPVGGFSLRGCLVSALEDNGVPAGVKGNVQGNLFKIITKKDIHYYIQASSKAERTQWIEAIKPLT", "length": 321, "header": "tr|A0A8V0ZIS2-1|A0A8V0ZIS2_CHICK Computationally mapped isoform of Pleckstrin 2 OS=Gallus gallus OX=9031 GN=PLEK2 PE=4 SV=1 CANONICAL=E1BT20-1" }, "locus": { "chromosome": "5", "start_pos": 28471688, "end_pos": 28463883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048288.1", "url": "https://www.ensembl.org/id/ENSGALT00010048288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028473.1", "url": "https://www.ensembl.org/id/ENSGALP00010028473.1" } ] } }, { "isoform_ac": "E1BT20-1", "url": "https://www.uniprot.org/uniprotkb/E1BT20/entry#E1BT20-1", "sequence": { "sequence": "MEETTGVLKEGFLVKRGHIVHNWKVRWFVLLQDKLLYYKLEGGKKESSPKGRILLDGCTITCPCLEYENRPLLIKLKTKTNTDYFLECCSREERDSWALDITGAIHAGHPVQVQELHRMKNSFKLLENISLHHIVDKMRDSSTGIKLTLNVEQGNRYKETFTGSALVDWLISNSFAVSRFEAVTLASMLMEENFTKPVGARSTGATRYSDLSEQFLDDSTALYMFAETSKKMLSSKEELQFNISELSGTIVKQGYLVKQGHKRKNWKVRKFVLRADPAFLHYYDPTKEENRPVGGFSLRGCLVSALEDNGVPAGVKGNVQGNLFKIITKKDIHYYIQASSKAERTQWIEAIKPLT", "length": 355, "header": "tr|E1BT20-1|E1BT20_CHICK Isoform 1 of Pleckstrin-2 OS=Gallus gallus OX=9031 GN=PLEK2 PE=4 SV=3 CANONICAL=E1BT20-1" }, "locus": { "chromosome": "5", "start_pos": 28471688, "end_pos": 28463883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048300.1", "url": "https://www.ensembl.org/id/ENSGALT00010048300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028479.1", "url": "https://www.ensembl.org/id/ENSGALP00010028479.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423278", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423278", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HJ10-1", "protein_name": "Pleckstrin-2", "gene_name": "Plek2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLLYYKLEGGRRVTPPKGRILLDGCTITCPCLEYENRPLLIKLKTRTSTEYFLEACSREERDSWAFEITGAIHSGQPGKVQQLHIQKNSFKLPPHISLHRIVDKMHDSSSGIRPCPNMEQGSTYKKTFLGSSLVDWLISSSFAASRLEGVTLASMLMEENFLRPVGVRSMGAIRAGDLVEQFLDDSTALYTFAESYKKKVSSKEEISLSTMELSGVVVKQGYLSKQGHKRKNWKVRRFVLRRDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT", "length": 353 }, "evidence": [ { "id": "E1BT20", "url": "https://omabrowser.org/oma/group/E1BT20/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4ACD5-1", "protein_name": "Pleckstrin-2", "gene_name": "Plek2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLLYYKLEGGRRVTPPKGRIVLDGCTITCPCLEYENRPLLIKLKTRTSTEYFLEACSREERDAWAFEITGAIHAGQPGKIQQLHILKNSFKLSPNISLHRIVDKMHDTSSGLRPSPNMEQGSTYKKTFLGSSLVDWLISSNFAASRLEAVTLASMLMEENFLRPVGVRSMDAIRSGDLAEQFLDDSTALYTFAESYKKKVSSKEEISLSTMELSGIVVKQGYLSKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEDNRPVGGFSLRGSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASNKAERAEWIEAIKKLT", "length": 353 }, "evidence": [ { "id": "E1BT20", "url": "https://omabrowser.org/oma/group/E1BT20/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SA39-1", "protein_name": "Pleckstrin-2", "gene_name": "PLEK2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDGVLKEGFLVKRGHIVHNWKVRWFILRQNTLLYYKLEAGRKVNPPKGRILLDGCTITCPCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQPGKVQQLHILKNSFKLPPHISLHRIIDKMHDSSSGIRPSPNMEQGSTYKKTFIGSSLVDWLISNSFAASRLEAVTLASMLMEENFLRPVGARSTGAIRSGDLVEQFLDDSTALYTFAESCKKKISPKEEISLSTVELSGTVVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERSEWIEAIKQLT", "length": 353 }, "evidence": [ { "id": "E1BT20", "url": "https://omabrowser.org/oma/group/E1BT20/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NYT0-1", "protein_name": "Pleckstrin-2", "gene_name": "PLEK2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLVYYKLEGGRRVTPPKGRILLDGCTITCPCLEYENRPLLIKLKTQTSTEYFLEACSREERDAWAFEITGAIHAGQPGKVQQLHSLRNSFKLPPHISLHRIVDKMHDSNTGIRSSPNMEQGSTYKKTFLGSSLVDWLISNSFTASRLEAVTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAESYKKKISPKEEISLSTVELSGTVVKQGYLAKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT", "length": 353 }, "evidence": [ { "id": "E1BT20", "url": "https://omabrowser.org/oma/group/E1BT20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WV52-1", "protein_name": "Pleckstrin-2", "gene_name": "Plek2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDGVLKEGFLVKRGHIVHNWKARWFILRQNTLLYYKLEGGRRVTPPKGRIVLDGCTITCPCLEYENRPLLIKLKTRTSTEYFLEACSREERDSWAFEITGAIHAGQPGKIQQLHILKNSFKLPPHISLHRIVDKMHDTSTGIRPSPNMEQGSTYKKTFLGSSLVDWLISSNFAASRLEAVTLASMLMEENFLRPVGVRSMGAIRSGDLAEQFLDDSTALYTFAESYKKKVSSKEEISLSTMELSGTVVKQGYLSKQGHKRKNWKVRRFVLRKDPAFLHYYDPSKEENRPVGGFSLRGSLVSALEDNGVPTGVKGNVQGNLFKVITKDDTHYYIQASSKAERAEWIEAIKKLT", "length": 353 }, "evidence": [ { "id": "E1BT20", "url": "https://omabrowser.org/oma/group/E1BT20/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1BT20", "url": "https://www.uniprot.org/uniprotkb/E1BT20" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BT20", "url": "https://www.uniprot.org/uniprotkb/E1BT20" } ], "pmid": "" }, { "name": "lamellipodium membrane", "id": "GO:0031258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031258", "evidence": [ { "database": "UniProtKB", "id": "E1BT20", "url": "https://www.uniprot.org/uniprotkb/E1BT20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E1BT20", "url": "https://www.uniprot.org/uniprotkb/E1BT20" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1BT20", "url": "https://www.uniprot.org/uniprotkb/E1BT20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 242, "end_pos": 244 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BRS4-1", "uniprot_ac": "E1BRS4", "uniprot_id": "E1BRS4_CHICK", "mass": { "chemical_mass": 14327.0, "monoisotopic_mass": 14327.0 }, "refseq": { "ac": "NP_001186427", "name": "interferon-induced transmembrane protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186427" }, "gene_names": [ { "name": "IFITM5", "type": "recommended", "evidence": [ { "id": "E1BRS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRS4" } ] }, { "name": "Dspa1", "type": "synonym", "evidence": [ { "id": "NP_001186427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186427" } ] }, { "name": "IFITM5", "type": "synonym", "evidence": [ { "id": "NP_001186427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186427" } ] } ], "protein_names": [ { "name": "Dispanin A1", "type": "synonym", "evidence": [ { "id": "NP_001186427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186427" } ] }, { "name": "Interferon induced transmembrane protein 5", "type": "synonym", "evidence": [ { "id": "E1BRS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRS4/entry#names_and_taxonomy" } ] }, { "name": "interferon-induced transmembrane protein 5", "type": "synonym", "evidence": [ { "id": "NP_001186427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186427" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU439787.1, HAEK01119009.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000212.1. On Dec 9, 2010 this sequence version replaced XP_420924.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186427" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BRS4", "url": "https://www.uniprot.org/uniprotkb/E1BRS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFITM5", "url": "https://www.uniprot.org/uniprotkb/E1BRS4", "locus": { "chromosome": "5", "start_pos": 1789425, "end_pos": 1779018, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020810", "url": "https://www.ensembl.org/id/ENSGALG00010020810" } ] } } ], "crossref": [ { "id": "E1BRS4", "url": "https://alphafold.ebi.ac.uk/entry/E1BRS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004239", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004239", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422992", "url": "https://www.ncbi.nlm.nih.gov/gene/422992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422992", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYPREDY", "url": "https://omabrowser.org/oma/group/SYPREDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG27", "url": "https://www.orthodb.org/?gene=A0A8V0ZG27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BRS4", "url": "https://www.orthodb.org/?gene=E1BRS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13999:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13999:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186427", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BRS4", "url": "https://www.uniprot.org/uniprotkb/E1BRS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BRS4-1", "url": "https://www.uniprot.org/uniprotkb/E1BRS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTSYPREDYLPMTSHKRDSSPTTATSAPPRDHLIWSIFNTIYMNFCCLGFVALAFSVKARDRKVAGDVEAARRFSSKARCYNALATAGSVLLPILLAALVVTGVLHLSKLAQDSVGFFSSQFSASDDEDK", "length": 131, "header": "tr|E1BRS4-1|E1BRS4_CHICK Isoform 1 of Interferon induced transmembrane protein 5 OS=Gallus gallus OX=9031 GN=IFITM5 PE=3 SV=1 CANONICAL=E1BRS4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG27-1", "url": "https://www.uniprot.org/uniprotkb/E1BRS4/entry#A0A8V0ZG27-1", "sequence": { "sequence": "MDTSYPREDYLPMTSHKRDSSPTTATSAPPRDHLIWSIFNTIYMNFCCLGFVALAFSVKVRHGWVPSGGVQGYRVIKVRKKLYDPQVQPHPTVPTDGVSQRHISKFLEHPWDGDTPTSLGSPCHCLTALLEKLFLTSNLKPCWRCLHVDLSSSSNTSTWTEGPGTGWRKPGGCLGVPMGSHCCPQSRLLQARDRKVAGDVEAARRFSSKARCYNALATAGSVLLPILLAALVVTGVLHLSKLAQDSVGFFSSQFSASDDEDK", "length": 262, "header": "tr|A0A8V0ZG27-1|A0A8V0ZG27_CHICK Computationally mapped isoform of Interferon induced transmembrane protein 5 OS=Gallus gallus OX=9031 GN=IFITM5 PE=3 SV=1 CANONICAL=E1BRS4-1" }, "locus": { "chromosome": "5", "start_pos": 1789312, "end_pos": 1788527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050334.1", "url": "https://www.ensembl.org/id/ENSGALT00010050334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029733.1", "url": "https://www.ensembl.org/id/ENSGALP00010029733.1" } ] } }, { "isoform_ac": "E1BRS4-1", "url": "https://www.uniprot.org/uniprotkb/E1BRS4/entry#E1BRS4-1", "sequence": { "sequence": "MDTSYPREDYLPMTSHKRDSSPTTATSAPPRDHLIWSIFNTIYMNFCCLGFVALAFSVKARDRKVAGDVEAARRFSSKARCYNALATAGSVLLPILLAALVVTGVLHLSKLAQDSVGFFSSQFSASDDEDK", "length": 131, "header": "tr|E1BRS4-1|E1BRS4_CHICK Isoform 1 of Interferon induced transmembrane protein 5 OS=Gallus gallus OX=9031 GN=IFITM5 PE=3 SV=1 CANONICAL=E1BRS4-1" }, "locus": { "chromosome": "5", "start_pos": 1782295, "end_pos": 1781510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050326.1", "url": "https://www.ensembl.org/id/ENSGALT00010050326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029726.1", "url": "https://www.ensembl.org/id/ENSGALP00010029726.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422992", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422992", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BC25-1", "protein_name": "Interferon induced transmembrane protein 5", "gene_name": "IFITM5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTSYPREDPRAPTPRKADGAHTALTLGAPRPPPRDHLIWSVFSTLYLNLCCLGFLALAYSIKARDQKVAGDLEAARRLGSKAKCYNILATMWALVPPLLLLALVVTGALHLSRLAKGSAAFFSTKFDDSDYD", "length": 133 }, "evidence": [ { "id": "E1BRS4", "url": "https://omabrowser.org/oma/group/E1BRS4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6NNB3-1", "protein_name": "Interferon-induced transmembrane protein 5", "gene_name": "IFITM5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTAYPREDTRAPTPSKAGAHTALTLGAPHPPPRDHLIWSVFSTLYLNLCCLGFLALAYSIKARDQKVVGDLEAARRFGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLARLAKDSAAFFSTKFDDADYD", "length": 132 }, "evidence": [ { "id": "E1BRS4", "url": "https://omabrowser.org/oma/group/E1BRS4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3V7W9-1", "protein_name": "Interferon induced transmembrane protein 5", "gene_name": "Ifitm5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTSYPREDPRAPSSRKADAAAHTALSVGTPGPTPRDHMLWSVFSTLYLNLCCLGFLALVHSVKARDKKVAGDLEAAKQYGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLSRLAKDSAAFFSTKFDEEDYN", "length": 134 }, "evidence": [ { "id": "E1BRS4", "url": "https://omabrowser.org/oma/group/E1BRS4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88728-1", "protein_name": "Interferon-induced transmembrane protein 5", "gene_name": "Ifitm5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSYPREDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALVHSVKARDQKMAGNLEAARQYGSKAKCYNILAAMWTLVPPLLLLGLVVTGALHLSKLAKDSAAFFSTKFDEEDYN", "length": 134 }, "evidence": [ { "id": "E1BRS4", "url": "https://omabrowser.org/oma/group/E1BRS4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BRS4", "url": "https://www.uniprot.org/uniprotkb/E1BRS4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1BRS4", "url": "https://www.uniprot.org/uniprotkb/E1BRS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "bone morphogenesis", "id": "GO:0060349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060349", "evidence": [ { "database": "UniProtKB", "id": "E1BRS4", "url": "https://www.uniprot.org/uniprotkb/E1BRS4" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "E1BRS4", "url": "https://www.uniprot.org/uniprotkb/E1BRS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BW35-1", "uniprot_ac": "E1BW35", "uniprot_id": "E1BW35_CHICK", "mass": { "chemical_mass": 66194.0, "monoisotopic_mass": 66194.0 }, "refseq": { "ac": "XP_015147548", "name": "kelch-like protein 25", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147548" }, "gene_names": [ { "name": "KLHL25", "type": "recommended", "evidence": [ { "id": "E1BW35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ] }, { "name": "KLHL25", "type": "synonym", "evidence": [ { "id": "XP_015147548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147548" } ] } ], "protein_names": [ { "name": "Kelch-like protein 25", "type": "recommended", "evidence": [ { "id": "E1BW35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW35/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 25", "type": "synonym", "evidence": [ { "id": "XP_015147548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147548" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147548" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL25", "url": "https://www.uniprot.org/uniprotkb/E1BW35", "locus": { "chromosome": "10", "start_pos": 13979964, "end_pos": 13959905, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020390", "url": "https://www.ensembl.org/id/ENSGALG00010020390" } ] } } ], "crossref": [ { "id": "ENSGALG00000006826", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006826", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18254", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18254", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18514", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18514", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770701", "url": "https://www.ncbi.nlm.nih.gov/gene/770701", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770701", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770701", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SNCLAMM", "url": "https://omabrowser.org/oma/group/SNCLAMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZKJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BW35", "url": "https://www.orthodb.org/?gene=E1BW35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BW35-1", "url": "https://www.uniprot.org/uniprotkb/E1BW35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVSVHENRKSRTSTGSMNILLFHKASHPDCVLSHLNTLRKHCMFTDVTLWAGNRSFPCHRAVLAASSRYFEAMFSNGLRESLDDEVNFHDSLHPEVLELLLDFAYSSRIIINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLYPSNCLGMMLLSDAHQCRRLYELSWRMCLVNFETVHKSEDFNNLSKDTLLDLISSDELEIEDEEMVFKAVLQWVKYDMDERKAYLPELLRNVRLALLPSECLKEALACEDLIMVDERNKLVLDEAIQCKKKILQNDGIVTSPCARPRKAGHTLLILGGQTFMCDKIYQVDQKAKEIIPKADLPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTAVAGVFPASPSVSLKQVEKYDPASNKWMMVAPLRDGVSNAAVVSARLKLFVFGGTSIHRDMVSKVQCYDPVENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETDQWTRIGDMTAKRMSCHALASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPS", "length": 589, "header": "tr|E1BW35-1|E1BW35_CHICK Isoform 1 of Kelch-like protein 25 OS=Gallus gallus OX=9031 GN=KLHL25 PE=4 SV=1 CANONICAL=E1BW35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKJ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BW35/entry#A0A8V0ZKJ0-1", "sequence": { "sequence": "MEDAAVSSDNPLSAHRAGNRSVIMSVSVHENRKSRTSTGSMNILLFHKASHPDCVLSHLNTLRKHCMFTDVTLWAGNRSFPCHRAVLAASSRYFEAMFSNGLRESLDDEVNFHDSLHPEVLELLLDFAYSSRIIINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLYPSNCLGMMLLSDAHQCRRLYELSWRMCLVNFETVHKSEDFNNLSKDTLLDLISSDELEIEDEEMVFKAVLQWVKYDMDERKAYLPELLRNVRLALLPSECLKEALACEDLIMVDERNKLVLDEAIQCKKKILQNDGIVTSPCARPRKAGHTLLILGGQTFMCDKIYQVDQKAKEIIPKADLPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTAVAGVFPASPSVSLKQVEKYDPASNKWMMVAPLRDGVSNAAVVSARLKLFVFGGTSIHRDMVSKVQCYDPVENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETDQWTRIGDMTAKRMSCHALASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPS", "length": 612, "header": "tr|A0A8V0ZKJ0-1|A0A8V0ZKJ0_CHICK Computationally mapped isoform of Kelch-like protein 25 OS=Gallus gallus OX=9031 GN=KLHL25 PE=4 SV=1 CANONICAL=E1BW35-1" }, "locus": { "chromosome": "10", "start_pos": 13973688, "end_pos": 13969502, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049270.1", "url": "https://www.ensembl.org/id/ENSGALT00010049270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029123.1", "url": "https://www.ensembl.org/id/ENSGALP00010029123.1" } ] } }, { "isoform_ac": "E1BW35-1", "url": "https://www.uniprot.org/uniprotkb/E1BW35/entry#E1BW35-1", "sequence": { "sequence": "MSVSVHENRKSRTSTGSMNILLFHKASHPDCVLSHLNTLRKHCMFTDVTLWAGNRSFPCHRAVLAASSRYFEAMFSNGLRESLDDEVNFHDSLHPEVLELLLDFAYSSRIIINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLYPSNCLGMMLLSDAHQCRRLYELSWRMCLVNFETVHKSEDFNNLSKDTLLDLISSDELEIEDEEMVFKAVLQWVKYDMDERKAYLPELLRNVRLALLPSECLKEALACEDLIMVDERNKLVLDEAIQCKKKILQNDGIVTSPCARPRKAGHTLLILGGQTFMCDKIYQVDQKAKEIIPKADLPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTAVAGVFPASPSVSLKQVEKYDPASNKWMMVAPLRDGVSNAAVVSARLKLFVFGGTSIHRDMVSKVQCYDPVENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETDQWTRIGDMTAKRMSCHALASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPS", "length": 589, "header": "tr|E1BW35-1|E1BW35_CHICK Isoform 1 of Kelch-like protein 25 OS=Gallus gallus OX=9031 GN=KLHL25 PE=4 SV=1 CANONICAL=E1BW35-1" }, "locus": { "chromosome": "10", "start_pos": 13979476, "end_pos": 13978229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049274.1", "url": "https://www.ensembl.org/id/ENSGALT00010049274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029125.1", "url": "https://www.ensembl.org/id/ENSGALP00010029125.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770701", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770701", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KCH4-1", "protein_name": "Kelch-like protein 25", "gene_name": "enc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVSVHENRKSRTSTGSMNISLFHKPSHPDSVLTHLNTLRKQCMFTDVTLWAGDRSFPCHRAVLAACSRYFEAMFSGGLRESLDNEVNFRDSVHPEVLELLLDFAYSSRVIINEENAESLLEAGDMLQFHDIRDAAAEFLEKNLHASNCLGMMLLSDAHQCKRLYELSWRMCLIHFETLRDTEDFCGLSKDKLLDLILSDELEVEDEQIVFNAVMHWVRYDLDSRRDYLPELLRGLRLALLPSECLIEAVACEELVMSDKRSRQIVDEAMQCKKKILQNDGVVTSPCARPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKSDLPSPRKEFSACAIGCKVYVTGGRGSENGVSKDVWIYDTVHEEWSKGAPMLIARFGHGSAELENCLYVVGGHTAIAGVFPASPSVSLKQVERYDPLTNKWTMMAPLRDGVSNAAVVSAKLKLFVFGGTTIHRDKASKVQCYDPVENRWTIAAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETNLWTRVGDMTSKRMSCHAVASGNKLYVVGGYFGTQRCKTLDCYDPTSDSWNSITTVPYSLIPTAFVSTWKHLPA", "length": 589 }, "evidence": [ { "id": "E1BW35", "url": "https://omabrowser.org/oma/group/E1BW35/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3I353-1", "protein_name": "Kelch-like protein 25", "gene_name": "Klhl25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVSVHETRKSRSSTGSMNISLFHKASHPDCVLAHLNTLRKHRMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIVINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLSPSNCLGMMLLSDAHQCRRLYEFSCRMCLVHFETVRQSEDFNSLSKDTLLDLISSDELETEDERVVFEAILQWVKHDPEQRKAHLPLLLRSVRLALLPSDCLKEAVSGEALLMGDECTKLIIDEAFRCKTKILQNDGVVTSPFARPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKADLPSPRKEFSASAIGCKVYVTGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTSLAGIFPASPSVSLKQVEKYDPVANKWTMVAPMRDGVSNAAVVSAKLKLFVFGGTSIHRDMVSKVQCFDPSENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEYTAASAYRFDCETNQWTRIGDMTAKRMSCHALASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPA", "length": 589 }, "evidence": [ { "id": "E1BW35", "url": "https://omabrowser.org/oma/group/E1BW35/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4KLM4-1", "protein_name": "Kelch-like protein 25", "gene_name": "Klhl25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVSVHETRKSRSSTGSMNISVFHKASHPDCVLAHLNTLRKHCMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIVINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLSPSNCLGMMVLSDAHQCRRLYEFSCRMSLVHFETVRQSEDFNSLSRDTLLDLISRDELETEDERVVFEAILQWVKHDLEQRKVHLPLLLRNVRLALLPSDCLKKAVSGEALLMADECTKLIIDEAFRCKTKILLNDGVVTSPFARPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKADLPSPRKEFSASAIGCKVYVTGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTSLAGIFPASPSVSLKQVEKYDPGDNKWTMVAPMRDGVSNAAVVSAKLKLFVFGGTSIHRDMVSKVQCFDPSDNRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEYTAASAYRFDCETNQWTRIGDMTAKRMSCHAVASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITSVPYSLIPTAFVSTWKHLPA", "length": 589 }, "evidence": [ { "id": "E1BW35", "url": "https://omabrowser.org/oma/group/E1BW35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2P1-1", "protein_name": "Kelch-like protein 25", "gene_name": "Klhl25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVSVHETRKSRSSTGSMNISVFHKASHPDCVLAHLNTLRKHCMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIVINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLSPSNCLGMMVLSDAHQCRRLYEFSCRMSLVHFETVRQSEDFNSLSRDTLLDLISRDELETEDERVVFEAILQWVKHDLEQRKAHLPLLLRNVRLALLPSDCLKNAVSGEALLMADECTKLILDEAFRCKTKILLNDGVVTSPFARPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKADLPSPRKEFSASAIGCKVYVTGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTSLAGIFPASPSVSLKQVEKYDPGDNKWTMVAPMRDGVSNAAVVSAKLKLFVFGGTSIHRDMVSKVQCFDPSENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEYTAASAYRFDCETNQWTRIGDMTAKRMSCHAVASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPA", "length": 589 }, "evidence": [ { "id": "E1BW35", "url": "https://omabrowser.org/oma/group/E1BW35/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0H3-1", "protein_name": "Kelch-like protein 25", "gene_name": "KLHL25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVSVHETRKSRSSTGSMNVTLFHKASHPDCVLAHLNTLRKHCMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIAINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLFPSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFETVRQSEDFNSLSKDTLLDLISSDELETEDERVVFEAILQWVKHDLEPRKVHLPELLRSVRLALLPSDCLQEAVSSEALLMADERTKLIMDEALRCKTRILQNDGVVTSPCARPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKADLPSPRKEFSASAIGCKVYVTGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTSLAGVFPASPSVSLKQVEKYDPGANKWMMVAPLRDGVSNAAVVSAKLKLFVFGGTSIHRDMVSKVQCYDPSENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETNQWTRIGDMTAKRMSCHALASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPA", "length": 589 }, "evidence": [ { "id": "E1BW35", "url": "https://omabrowser.org/oma/group/E1BW35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "id": "GO:0032831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032831", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "negative regulation of fatty acid biosynthetic process", "id": "GO:0045717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045717", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "positive regulation of fatty acid oxidation", "id": "GO:0046321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046321", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E1BW35", "url": "https://www.uniprot.org/uniprotkb/E1BW35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BW35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW35" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 114, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BQ84-1", "uniprot_ac": "E1BQ84", "uniprot_id": "E1BQ84_CHICK", "mass": { "chemical_mass": 60674.0, "monoisotopic_mass": 60674.0 }, "refseq": { "ac": "NP_001264940", "name": "copine-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264940" }, "gene_names": [ { "name": "CPNE2", "type": "recommended", "evidence": [ { "id": "E1BQ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ] }, { "name": "CPNE2", "type": "synonym", "evidence": [ { "id": "NP_001264940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264940" } ] } ], "protein_names": [ { "name": "Copine-2", "type": "recommended", "evidence": [ { "id": "E1BQ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ84/entry#names_and_taxonomy" } ] }, { "name": "Copine II", "type": "synonym", "evidence": [ { "id": "E1BQ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ84/entry#names_and_taxonomy" } ] }, { "name": "copine II", "type": "synonym", "evidence": [ { "id": "NP_001264940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264940" } ] }, { "name": "copine-2", "type": "synonym", "evidence": [ { "id": "NP_001264940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264940" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01081490.1, HAEL01009992.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000247.1. On May 5, 2013 this sequence version replaced XP_003641934.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264940", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264940" } ] }, { "annotation": "Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Exhibits calcium-dependent cell membrane binding properties.", "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84#function" }, { "database": "UniProtKB", "id": "ARBA00053843", "url": "https://www.uniprot.org/uniprotkb/ARBA00053843#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLW7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZP37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP37#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPNE2", "url": "https://www.uniprot.org/uniprotkb/E1BQ84", "locus": { "chromosome": "11", "start_pos": 688182, "end_pos": 648064, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022150", "url": "https://www.ensembl.org/id/ENSGALG00010022150" } ] } } ], "crossref": [ { "id": "E1BQ84", "url": "https://alphafold.ebi.ac.uk/entry/E1BQ84", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001316", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001316", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415646", "url": "https://www.ncbi.nlm.nih.gov/gene/415646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415646", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415646", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLW7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLZ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLZ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP37", "url": "https://www.orthodb.org/?gene=A0A8V0ZP37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQ84", "url": "https://www.orthodb.org/?gene=E1BQ84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264940", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264940", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQ84-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYTGTPPPAGPIGSQYCVCKVELSICGQNLLDRDVTSKSDPFCVLFMEVNGKWVELDRTETAVNNLNPAFSKKFVVDYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGTIVSSKKITRTLLLGNGKPAGKGMITIAAQELSDNRVITLSMAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPIWKPFTVPLVSLCDGDVEKLIKVMCYDYDSDGGHDFIGEFQTSVARMCEAQDAFPLELECINPKKQKKKKNYKNSGIIIVKSCKITRDFSFLDYILGGCQLMFTVGIDFTASNGNPRDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVEGIVQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQEAASQYFILLIITDGVISDMDETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRVLRSHTGEEAVRDIVQFVPFRDFRNAPKETLAKAVLAELPQQVVQYFKHQNLPPINLEPA", "length": 544, "header": "tr|E1BQ84-1|E1BQ84_CHICK Isoform 1 of Copine-2 OS=Gallus gallus OX=9031 GN=CPNE2 PE=3 SV=3 CANONICAL=E1BQ84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLW7-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ84/entry#A0A8V0ZLW7-1", "sequence": { "sequence": "MAYTGTPPPAGPIGSQYCVCKVELSICGQNLLDRDVTSKSDPFCVLFMEVNGKWVELDRTETAVNNLNPAFSKKFVVDYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGTIVSSKKITRTLLLGNGKPAGKGMITVQQLIYLTHRLCAVVLPQDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPIWKPFTVPLVSLCDGDVEKLIKVMCYDYDSDGGHDFIGEFQTSVARMCEAQDAFPVSADTFSGQNGARAVITRDFSFLDYILGGCQLMFTVGIDFTASNGNPRDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVMCSSDPCA", "length": 357, "header": "tr|A0A8V0ZLW7-1|A0A8V0ZLW7_CHICK Computationally mapped isoform of Copine-2 OS=Gallus gallus OX=9031 GN=CPNE2 PE=3 SV=1 CANONICAL=E1BQ84-1" }, "locus": { "chromosome": "11", "start_pos": 678166, "end_pos": 655164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053879.1", "url": "https://www.ensembl.org/id/ENSGALT00010053879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032440.1", "url": "https://www.ensembl.org/id/ENSGALP00010032440.1" } ] } }, { "isoform_ac": "A0A8V0ZLZ0-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ84/entry#A0A8V0ZLZ0-1", "sequence": { "sequence": "MAYTGTPPPAGPIGSQYCVCKVELSICGQNLLDRDVTSKSDPFCVLFMEVNGKWVELDRTETAVNNLNPAFSKKFVVDYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGTIVSSKKITRTLLLGNGKPAGKGMITIAAQELSDNRVITLSMAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPIWKPFTVPLVSLCDGDVEKLIKVMCYDYDSDGGHDFIGEFQTSVARMCEAQDAFPLELECINPKKQKKKKNYKNSGIIIVKSCKITRDFSFLDYILGGCQLMFTVGIDFTASNGNPRDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVEGIVQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQEAASQYFILLIITDGVISDMDETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRVLRSHTGEEAVRDIVQFVPFRDFRNVSLCPPAVGPGAAVPSPGEEVAPGRPHCGLPVPTGTPGRMGRDSCQGM", "length": 557, "header": "tr|A0A8V0ZLZ0-1|A0A8V0ZLZ0_CHICK Computationally mapped isoform of Copine-2 OS=Gallus gallus OX=9031 GN=CPNE2 PE=3 SV=1 CANONICAL=E1BQ84-1" }, "locus": { "chromosome": "11", "start_pos": 687069, "end_pos": 655164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053906.1", "url": "https://www.ensembl.org/id/ENSGALT00010053906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032460.1", "url": "https://www.ensembl.org/id/ENSGALP00010032460.1" } ] } }, { "isoform_ac": "A0A8V0ZLZ5-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ84/entry#A0A8V0ZLZ5-1", "sequence": { "sequence": "MLASISPDCGCLTGAQNARCQQSPAAVLAASGLTRCCVEISVRFKKLRYGMRSDCLELLLLLESMAYTGTPPPAGPIGSQYCVCKVELSICGQNLLDRDVTSKSDPFCVLFMEVNGKWVELDRTETAVNNLNPAFSKKFVVDYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGTIVSSKKITRTLLLGNGKPAGKGMITIAAQELSDNRVITLSMAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPIWKPFTVPLVSLCDGDVEKLIKVMCYDYDSDGGHDFIGEFQTSVARMCEAQDAFPLELECINPKKQKKKKNYKNSGIIIVKSCKITRDFSFLDYILGGCQLMFTVGIDFTASNGNPRDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVEGIVQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQEAASQYFILLIITDGVISDMDETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRVLRSHTGEEAVRDIVQFVPFRDFRNAPKETLAKAVLAELPQQVVQYFKHQNLPPINLEPA", "length": 608, "header": "tr|A0A8V0ZLZ5-1|A0A8V0ZLZ5_CHICK Computationally mapped isoform of Copine-2 OS=Gallus gallus OX=9031 GN=CPNE2 PE=3 SV=1 CANONICAL=E1BQ84-1" }, "locus": { "chromosome": "11", "start_pos": 687690, "end_pos": 648263, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053911.1", "url": "https://www.ensembl.org/id/ENSGALT00010053911.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032465.1", "url": "https://www.ensembl.org/id/ENSGALP00010032465.1" } ] } }, { "isoform_ac": "A0A8V0ZP37-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ84/entry#A0A8V0ZP37-1", "sequence": { "sequence": "MVSFKPSWRFLTHPSPQPGLLARVCRAVPGSSDCLELLLLLESMAYTGTPPPAGPIGSQYCVCKVELSICGQNLLDRDVTSKSDPFCVLFMEVNGKWVELDRTETAVNNLNPAFSKKFVVDYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGTIVSSKKITRTLLLGNGKPAGKGMITIAAQELSDNRVITLSMAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPIWKPFTVPLVSLCDGDVEKLIKVMCYDYDSDGGHDFIGEFQTSVARMCEAQDAFPLELECINPKKQKKKKNYKNSGIIIVKSCKITRDFSFLDYILGGCQLMFTVGIDFTASNGNPRDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVEGIVQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQEAASQYFILLIITDGVISDMDETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRVLRSHTGEEAVRDIVQFVPFRDFRNAPKETLAKAVLAELPQQVVQYFKHQNLPPINLEPA", "length": 587, "header": "tr|A0A8V0ZP37-1|A0A8V0ZP37_CHICK Computationally mapped isoform of Copine-2 OS=Gallus gallus OX=9031 GN=CPNE2 PE=3 SV=1 CANONICAL=E1BQ84-1" }, "locus": { "chromosome": "11", "start_pos": 687690, "end_pos": 649477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053895.1", "url": "https://www.ensembl.org/id/ENSGALT00010053895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032451.1", "url": "https://www.ensembl.org/id/ENSGALP00010032451.1" } ] } }, { "isoform_ac": "E1BQ84-1", "url": "https://www.uniprot.org/uniprotkb/E1BQ84/entry#E1BQ84-1", "sequence": { "sequence": "MAYTGTPPPAGPIGSQYCVCKVELSICGQNLLDRDVTSKSDPFCVLFMEVNGKWVELDRTETAVNNLNPAFSKKFVVDYHFEEVQKLKFALFDQDKSSTQLYEHDFLGEFSCTLGTIVSSKKITRTLLLGNGKPAGKGMITIAAQELSDNRVITLSMAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPIWKPFTVPLVSLCDGDVEKLIKVMCYDYDSDGGHDFIGEFQTSVARMCEAQDAFPLELECINPKKQKKKKNYKNSGIIIVKSCKITRDFSFLDYILGGCQLMFTVGIDFTASNGNPRDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVEGIVQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQEAASQYFILLIITDGVISDMDETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRVLRSHTGEEAVRDIVQFVPFRDFRNAPKETLAKAVLAELPQQVVQYFKHQNLPPINLEPA", "length": 544, "header": "tr|E1BQ84-1|E1BQ84_CHICK Isoform 1 of Copine-2 OS=Gallus gallus OX=9031 GN=CPNE2 PE=3 SV=3 CANONICAL=E1BQ84-1" }, "locus": { "chromosome": "11", "start_pos": 687690, "end_pos": 655164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053902.1", "url": "https://www.ensembl.org/id/ENSGALT00010053902.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032457.1", "url": "https://www.ensembl.org/id/ENSGALP00010032457.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415646", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "E1BQ84", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1BQ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQ84" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 127, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BVB1-1", "uniprot_ac": "E1BVB1", "uniprot_id": "E1BVB1_CHICK", "mass": { "chemical_mass": 15916.0, "monoisotopic_mass": 15916.0 }, "refseq": { "ac": "NP_001239184", "name": "large ribosomal subunit protein eL32", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239184" }, "gene_names": [ { "name": "RPL32", "type": "recommended", "evidence": [ { "id": "E1BVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVB1" } ] }, { "name": "RPL32", "type": "synonym", "evidence": [ { "id": "NP_001239184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239184" } ] } ], "protein_names": [ { "name": "60S ribosomal protein L32", "type": "recommended", "evidence": [ { "id": "E1BVB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVB1/entry#names_and_taxonomy" } ] }, { "name": "large ribosomal subunit protein eL32", "type": "synonym", "evidence": [ { "id": "NP_001239184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239184" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX270812.4, CV855031.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000252.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001239184", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239184" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BVB1", "url": "https://www.uniprot.org/uniprotkb/E1BVB1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPL32", "url": "https://www.uniprot.org/uniprotkb/E1BVB1", "locus": { "chromosome": "12", "start_pos": 19656929, "end_pos": 19659744, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019093", "url": "https://www.ensembl.org/id/ENSGALG00010019093" } ] } } ], "crossref": [ { "id": "E1BVB1", "url": "https://alphafold.ebi.ac.uk/entry/E1BVB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027142", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027142", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00513", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00513", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416122", "url": "https://www.ncbi.nlm.nih.gov/gene/416122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR001515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416122", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416122", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPSGYEE", "url": "https://omabrowser.org/oma/group/HPSGYEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2T8", "url": "https://www.orthodb.org/?gene=A0A8V0Z2T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BVB1", "url": "https://www.orthodb.org/?gene=E1BVB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23413", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23413", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23413:SF1", "url": 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1NTV9-1", "uniprot_ac": "F1NTV9", "uniprot_id": "F1NTV9_CHICK", "mass": { "chemical_mass": 50467.0, "monoisotopic_mass": 50467.0 }, "refseq": { "ac": "NP_001029994", "name": "endoplasmic reticulum membrane adapter protein XK precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" }, "gene_names": [ { "name": "XK", "type": "recommended", "evidence": [ { "id": "F1NTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ] }, { "name": "XK", "type": "synonym", "evidence": [ { "id": "NP_001029994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] }, { "name": "XRG1", "type": "synonym", "evidence": [ { "id": "NP_001029994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "F1NTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTV9/entry#names_and_taxonomy" } ] }, { "name": "X-linked Kx blood group (McLeod syndrome)", "type": "synonym", "evidence": [ { "id": "NP_001029994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] }, { "name": "XK, Kell blood group complex subunit", "type": "synonym", "evidence": [ { "id": "NP_001029994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] }, { "name": "XK-related protein 1", "type": "synonym", "evidence": [ { "id": "NP_001029994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] }, { "name": "endoplasmic reticulum membrane adapter protein XK precursor", "type": "synonym", "evidence": [ { "id": "NP_001029994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] }, { "name": "membrane transport protein XK", "type": "synonym", "evidence": [ { "id": "NP_001029994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY699712.1, HAEK01086507.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000021.1. On Sep 23, 2021 this sequence version replaced NP_001029994.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001029994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "XK", "url": "https://www.uniprot.org/uniprotkb/F1NTV9", "locus": { "chromosome": "1", "start_pos": 113285260, "end_pos": 113339967, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001878", "url": "https://www.ensembl.org/id/ENSGALG00010001878" } ] } } ], "crossref": [ { "id": "F1NTV9", "url": "https://alphafold.ebi.ac.uk/entry/F1NTV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016262", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016262", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427991", "url": "https://www.ncbi.nlm.nih.gov/gene/427991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427991", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427991", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SGGDGMW", "url": "https://omabrowser.org/oma/group/SGGDGMW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X7G3", "url": "https://www.orthodb.org/?gene=A0A8V0X7G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NTV9", "url": "https://www.orthodb.org/?gene=F1NTV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14297:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14297:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001029994", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001029994", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0X7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X7G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTV9-1", "url": "https://www.uniprot.org/uniprotkb/F1NTV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFPGSVLISLVLFVAETATALCLSGAYRAAGDRMWQWLTLLFALLPCALVQLSLVFIHRDVSRDRPLVLLLHLLQLGPLVRCVEVFYIYFHAGRVEEPYVSITKKRQMPKDGYSEEVEKEVGQAEGKLCTHRSAFSRASVIQAFLGSAPQLTLQLYICVLQQEITAARSIFMVLSLLSIVYGALRCNILAIKIKYDDYDVSVKPAAYLCIFMWRSFEIATRVTVLVLFSSVLQIWTLPVVLVNFFGFFFYPWILFWQSKSPFPENIEKALSRVGTTIVLCLLTFLYAGINMFCWSAVQVKLNDPDLINKSQNWYRLTVYYMLRFIENAFLLLMWYIYRTDIYLYVCAPLLVLQLLIAYCMAILFMLVFYQFCHPCKKLFSSSITEGLLSSFTFCFVCKSPKSSTLTDKADLKSSENADESQSSNKTIDSPNGNPHQSVSSNA", "length": 443, "header": "tr|F1NTV9-1|F1NTV9_CHICK Isoform 1 of XK-related protein OS=Gallus gallus OX=9031 GN=XK PE=3 SV=2 CANONICAL=F1NTV9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X7G3-1", "url": "https://www.uniprot.org/uniprotkb/F1NTV9/entry#A0A8V0X7G3-1", "sequence": { "sequence": "MEVLTPAQIKSICLAILESGKQYAVKKRKPFPLMYSYYGTEYLGAAHGLSSILQMLLSYFEYLQPADQELVWQSVDFLMDQEQNSNWPPELGETIERENELVHWCHGAPGIAYLFAKAYLVSKKPQYLDTCIRCGELTWQKGLLKKGPGICHGVAGSAYVFLLLYRLTGNSKYIYRAQRCVEVFYIYFHAGRVEEPYVSITKKRQMPKDGYSEEVEKEVGQAEGKLCTHRSAFSRASVIQAFLGSAPQLTLQLYICVLQQEITAARSIFMVLSLLSIVYGALRCNILAIKIKYDDYDVSVKPAAYLCIFMWRSFEIATRVTVLVLFSSVLQIWTLPVVLVNFFGFFFYPWILFWQSKSPFPENIEKALSRVGTTIVLCLLTFLYAGINMFCWSAVQVKLNDPDLINKSQNWYRLTVYYMLRFIENAFLLLMWYIYRTDIYLYVCAPLLVLQLLIAYCMAILFMLVFYQFCHPCKKLFSSSITEGLLSSFTFCFVCKSPKSSTLTDKADLKSSENADESQSSNKTIDSPNGNPHQSVSSNA", "length": 540, "header": "tr|A0A8V0X7G3-1|F1NTV9_CHICK Computationally mapped isoform of XK-related protein OS=Gallus gallus OX=9031 GN=XK PE=3 SV=1 CANONICAL=F1NTV9-1" }, "locus": { "chromosome": "1", "start_pos": 113339699, "end_pos": 113288370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004278.1", "url": "https://www.ensembl.org/id/ENSGALT00010004278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002571.1", "url": "https://www.ensembl.org/id/ENSGALP00010002571.1" } ] } }, { "isoform_ac": "F1NTV9-1", "url": "https://www.uniprot.org/uniprotkb/F1NTV9/entry#F1NTV9-1", "sequence": { "sequence": "MKFPGSVLISLVLFVAETATALCLSGAYRAAGDRMWQWLTLLFALLPCALVQLSLVFIHRDVSRDRPLVLLLHLLQLGPLVRCVEVFYIYFHAGRVEEPYVSITKKRQMPKDGYSEEVEKEVGQAEGKLCTHRSAFSRASVIQAFLGSAPQLTLQLYICVLQQEITAARSIFMVLSLLSIVYGALRCNILAIKIKYDDYDVSVKPAAYLCIFMWRSFEIATRVTVLVLFSSVLQIWTLPVVLVNFFGFFFYPWILFWQSKSPFPENIEKALSRVGTTIVLCLLTFLYAGINMFCWSAVQVKLNDPDLINKSQNWYRLTVYYMLRFIENAFLLLMWYIYRTDIYLYVCAPLLVLQLLIAYCMAILFMLVFYQFCHPCKKLFSSSITEGLLSSFTFCFVCKSPKSSTLTDKADLKSSENADESQSSNKTIDSPNGNPHQSVSSNA", "length": 443, "header": "tr|F1NTV9-1|F1NTV9_CHICK Isoform 1 of XK-related protein OS=Gallus gallus OX=9031 GN=XK PE=3 SV=2 CANONICAL=F1NTV9-1" }, "locus": { "chromosome": "1", "start_pos": 113302655, "end_pos": 113288370, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004276.1", "url": "https://www.ensembl.org/id/ENSGALT00010004276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002569.1", "url": "https://www.ensembl.org/id/ENSGALP00010002569.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427991", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427991", "resource": "KEGG Pathway" }, { "id": "R-GGA-375276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "resource": "Reactome", "description": "Peptide ligand-binding receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZKL8-1", "protein_name": "XK-related protein", "gene_name": "XK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKFPGSVLASVFLFVAETTTALYLSSTYRSRGDGMWQALTLLFSLLPCALVQLTLLFVHRDFSRDRPLVLLLHLLQLGPLFRCFEVFCIYCQSGRIEEPYVSITRKRQMPKNGLSEEIEKEVGQAEGKLFTHRSAFSRASVIQAFLGSAPQLTLQLYISTLQQHVTVSRGVFMGLSLLSIVYGALRCNILAIKIKYDEYEVKVKPLAYVCIFLWRSFEIATRVIVLVLFTSVLKAWVVIDILINFLSFFFYPWILFWCSGSPFPENIEKALSRVGTTIVLGFLTLLYAGINMFCWSAVQLKINSPDLISKSQNWYRLLVYYMLRFIENAFLLLLWYLYKTDIYMYVCAPLLILQLLVGYCTAILFMVVFYQFFHPCKKLFSSSVSESVQKWFECACSDCRPQRSCESAEKSDLRSPADREETPSSSKISSVPSQILNADEFSSA", "length": 444 }, "evidence": [ { "id": "F1NTV9", "url": "https://omabrowser.org/oma/group/F1NTV9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P51811-1", "protein_name": "Endoplasmic reticulum membrane adapter protein XK", "gene_name": "XK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFPASVLASVFLFVAETTAALSLSSTYRSGGDRMWQALTLLFSLLPCALVQLTLLFVHRDLSRDRPLVLLLHLLQLGPLFRCFEVFCIYFQSGNNEEPYVSITKKRQMPKNGLSEEIEKEVGQAEGKLITHRSAFSRASVIQAFLGSAPQLTLQLYISVMQQDVTVGRSLLMTISLLSIVYGALRCNILAIKIKYDEYEVKVKPLAYVCIFLWRSFEIATRVVVLVLFTSVLKTWVVVIILINFFSFFLYPWILFWCSGSPFPENIEKALSRVGTTIVLCFLTLLYTGINMFCWSAVQLKIDSPDLISKSHNWYQLLVYYMIRFIENAILLLLWYLFKTDIYMYVCAPLLVLQLLIGYCTAILFMLVFYQFFHPCKKLFSSSVSEGFQRWLRCFCWACRQQKPCEPIGKEDLQSSRDRDETPSSSKTSPEPGQFLNAEDLCSA", "length": 444 }, "evidence": [ { "id": "F1NTV9", "url": "https://omabrowser.org/oma/group/F1NTV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXY7-1", "protein_name": "Endoplasmic reticulum membrane adapter protein XK", "gene_name": "Xk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFPASVIASVFLFVAETAAALYLSSTYRSAGDRMWQVLTLLFSLMPCALVQFTLLFVHRDLSRDRPLALLMHLLQLGPLYRCCEVFCIYCQSDQNEEPYVSITKKRQMPKDGLSEEVEKEVGQAEGKLITHRSAFSRASVIQAFLGSAPQLTLQLYITVLEQNITTGRCFIMTLSLLSIVYGALRCNILAIKIKYDEYEVKVKPLAYVCIFLWRSFEIATRVIVLVLFTSVLKIWVVAVILVNFFSFFLYPWIVFWCSGSPFPENIEKALSRVGTTIVLCFLTLLYAGINMFCWSAVQLKIDNPELISKSQNWYRLLIYYMTRFIENSVLLLLWYFFKTDIYMYVCAPLLILQLLIGYCTGILFMLVFYQFFHPCKKLFSSSVSESFRALLRCACWSSLRRKSSEPVGRIDTDLKACTEQDVMPTTSKVIPEATDIWTAVDLCSA", "length": 446 }, "evidence": [ { "id": "F1NTV9", "url": "https://omabrowser.org/oma/group/F1NTV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ], "pmid": "" }, { "name": "peptide modification", "id": "GO:0031179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031179", "evidence": [ { "database": "UniProtKB", "id": "F1NTV9", "url": "https://www.uniprot.org/uniprotkb/F1NTV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V0X7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3#function" }, { "id": "A0A8V0X7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3" }, { "id": "PIRSR607822-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607822-1" } ], "binding_site_uniprot": 105, "amino_acid": "Lys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 105, "end_pos": 105, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0X7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3#function" }, { "id": "A0A8V0X7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3" }, { "id": "PIRSR607822-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607822-1" } ], "binding_site_uniprot": 151, "amino_acid": "Gln", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 151, "end_pos": 151, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0X7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3#function" }, { "id": "A0A8V0X7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7G3" }, { "id": "PIRSR607822-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR607822-1" } ], "binding_site_uniprot": 152, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 152, "end_pos": 152, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 309, "end_pos": 311 }, { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NH08-1", "uniprot_ac": "F1NH08", "uniprot_id": "F1NH08_CHICK", "mass": { "chemical_mass": 61115.0, "monoisotopic_mass": 61115.0 }, "refseq": { "ac": "NP_989535", "name": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989535" }, "gene_names": [ { "name": "UGT8", "type": "recommended", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ] }, { "name": "UGT8", "type": "synonym", "evidence": [ { "id": "NP_989535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989535" } ] } ], "protein_names": [ { "name": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase", "type": "recommended", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#names_and_taxonomy" } ] }, { "name": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor", "type": "synonym", "evidence": [ { "id": "NP_989535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989535" } ] }, { "name": "2-hydroxyacylsphingosine 1-beta-galactosyltransferase", "type": "synonym", "evidence": [ { "id": "NP_989535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989535" } ] }, { "name": "2.4.1.47", "type": "synonym", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#names_and_taxonomy" } ] }, { "name": "Ceramide UDP-galactosyltransferase", "type": "synonym", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#names_and_taxonomy" } ] }, { "name": "Cerebroside synthase", "type": "synonym", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#names_and_taxonomy" } ] }, { "name": "UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)", "type": "synonym", "evidence": [ { "id": "NP_989535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989535" } ] }, { "name": "UDP-galactose-ceramide galactosyltransferase", "type": "synonym", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888531.235620.1, SRR13267651.31449.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000074.1. On Sep 29, 2021 this sequence version replaced NP_989535.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989535" } ] }, { "annotation": "Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. Galactosylates both hydroxy- and non-hydroxy fatty acid-containing ceramides and diglycerides.", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08#function" }, { "database": "UniProtKB", "id": "ARBA00058061", "url": "https://www.uniprot.org/uniprotkb/ARBA00058061#function" }, { "database": "UniProtKB", "id": "A0A8V0XAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAD6#function" }, { "database": "UniProtKB", "id": "A0A8V0XH90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH90#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UGT8", "url": "https://www.uniprot.org/uniprotkb/F1NH08", "locus": { "chromosome": "4", "start_pos": 55767004, "end_pos": 55811257, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003761", "url": "https://www.ensembl.org/id/ENSGALG00010003761" } ] } } ], "crossref": [ { "id": "F1NH08", "url": "https://alphafold.ebi.ac.uk/entry/F1NH08", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012018", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012018", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03784", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374033", "url": "https://www.ncbi.nlm.nih.gov/gene/374033", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374033", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374033", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPHERHI", "url": "https://omabrowser.org/oma/group/DPHERHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XAD6", "url": "https://www.orthodb.org/?gene=A0A8V0XAD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XH90", "url": "https://www.orthodb.org/?gene=A0A8V0XH90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NH08", "url": "https://www.orthodb.org/?gene=F1NH08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48043:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48043:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13093", "url": "https://www.rhea-db.org/rhea/13093", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "21032", "url": "https://www.rhea-db.org/rhea/21032", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43400", "url": "https://www.rhea-db.org/rhea/43400", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43404", "url": "https://www.rhea-db.org/rhea/43404", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "48344", "url": "https://www.rhea-db.org/rhea/48344", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XAD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XAD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XH90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XH90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XH90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH08-1", "url": "https://www.uniprot.org/uniprotkb/F1NH08-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPYTSVFILLWSAVGIARAAKIVVVPPIMFESHLYIFKTLASALHDQGHQTVFLLSEGREIPPSNHYRLKRYPGIFNSSTSDDFLQSKMRSIFSGRLTALELFDILDHYSKNCDMIVGNQNLMHALKQEKFDLLLVDPNEMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLSYVPEFNSLLTDRMNLFERMKNTFVYVISRFGVSFLVLPKYERIMQKHKVLPERSMYDLVHGSSLWMLCTDIALEFPRPTLPNVVYVGGILTKPASPLPEDLQTWVNGANENGFVLVSFGAGVKYLSEDVANKLARALARLPQRVIWRFSGNKPRNLGNNTKLIEWLPQNDLLGHPNIKAFLSHGGLNSIFETMYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLNWKTVTESELYEALEKVINDPSYRQRAQRLSEIHKDQPGHPVNRTVYWINYILRHNGAQHLRAAVYSISLYQYFLLDIAFVVLVGAALFYYSLAKLTKFIRKQGKHIWSNDEHSTVNGHYQNGIPNGKHRRNGHIKHE", "length": 537, "header": "tr|F1NH08-1|F1NH08_CHICK Isoform 1 of 2-hydroxyacylsphingosine 1-beta-galactosyltransferase OS=Gallus gallus OX=9031 GN=UGT8 PE=1 SV=3 CANONICAL=F1NH08-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XAD6-1", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#A0A8V0XAD6-1", "sequence": { "sequence": "MISFNIGSSSRRRLHQMLILFNYCAMKPYTSVFILLWSAVGIARAAKIVVVPPIMFESHLYIFKTLASALHDQGHQTVFLLSEGREIPPSNHYRLKRYPGIFNSSTSDDFLQSKMRSIFSGRLTALELFDILDHYSKNCDMIVGNQNLMHALKQEKFDLLLVDPNEMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLSYVPEFNSLLTDRMNLFERMKNTFVYVISRFGVSFLVLPKYERIMQKHKVLPERSMYDLVHGSSLWMLCTDIALEFPRPTLPNVVYVGGILTKPASPLPEDLQTWVNGANENGFVLVSFGAGVKYLSEDVANKLARALARLPQRVIWRFSGNKPRNLGNNTKLIEWLPQNDLLGHPNIKAFLSHGGLNSIFETMYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLNWKTVTESELYEALEKVINDPSYRQRAQRLSEIHKDQPGHPVNRTVYWINYILRHNGAQHLRAAVYSISLYQYFLLDIAFVVLVGAALFYYSLAKLTKFIRKQGKHIWSNDEHSTVNGHYQNGIPNGKHRRNGHIKHE", "length": 562, "header": "tr|A0A8V0XAD6-1|A0A8V0XAD6_CHICK Computationally mapped isoform of 2-hydroxyacylsphingosine 1-beta-galactosyltransferase OS=Gallus gallus OX=9031 GN=UGT8 PE=1 SV=1 CANONICAL=F1NH08-1" }, "locus": { "chromosome": "4", "start_pos": 55796728, "end_pos": 55767558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008690.1", "url": "https://www.ensembl.org/id/ENSGALT00010008690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005082.1", "url": "https://www.ensembl.org/id/ENSGALP00010005082.1" } ] } }, { "isoform_ac": "A0A8V0XH90-1", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#A0A8V0XH90-1", "sequence": { "sequence": "MKPYTSVFILLWSAVGIARAAKIVVVPPIMFESHLYIFKTLASALHDQGHQTVFLLSEGREIPPSNHYRLKRYPGIFNSSTSDDFLQSKMRSIFSGRLTALELFDILDHYSKNCDMIVGNQNLMHALKQEKFDLLLVDPNEMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLSYVPEFNSLLTDRMNLFERMKNTFVYVISRFGVSFLVLPKYERIMQKHKVLPERSMYDLVHGSSLWMLCTDIALEFPRPTLPNVVYVGGILTKPASPLPEDLQTWVNGANENGFVLVSFGAGVKYLSEDVANKLARALARLPQRVIWRFSGNKPRNLGNNTKLIEWLPQNDLLGHPNIKAFLSHGGLNSIFETMYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLNWKTVTESELYEALEKVINDPSYRQRAQRLSEIHKDQPGHPVNRTVYWINYILRHNGAQHLRAAVYSISLYQYFLLDIAFVVLVGAALFYYSLAKLTKFIRKQGKHIWSNDEHSTVK", "length": 516, "header": "tr|A0A8V0XH90-1|F1NH08_CHICK Computationally mapped isoform of 2-hydroxyacylsphingosine 1-beta-galactosyltransferase OS=Gallus gallus OX=9031 GN=UGT8 PE=1 SV=1 CANONICAL=F1NH08-1" }, "locus": { "chromosome": "4", "start_pos": 55792787, "end_pos": 55767546, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008693.1", "url": "https://www.ensembl.org/id/ENSGALT00010008693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005084.1", "url": "https://www.ensembl.org/id/ENSGALP00010005084.1" } ] } }, { "isoform_ac": "F1NH08-1", "url": "https://www.uniprot.org/uniprotkb/F1NH08/entry#F1NH08-1", "sequence": { "sequence": "MKPYTSVFILLWSAVGIARAAKIVVVPPIMFESHLYIFKTLASALHDQGHQTVFLLSEGREIPPSNHYRLKRYPGIFNSSTSDDFLQSKMRSIFSGRLTALELFDILDHYSKNCDMIVGNQNLMHALKQEKFDLLLVDPNEMCGFVIAHLLGVKYAVFSTGLWYPAEVGAPAPLSYVPEFNSLLTDRMNLFERMKNTFVYVISRFGVSFLVLPKYERIMQKHKVLPERSMYDLVHGSSLWMLCTDIALEFPRPTLPNVVYVGGILTKPASPLPEDLQTWVNGANENGFVLVSFGAGVKYLSEDVANKLARALARLPQRVIWRFSGNKPRNLGNNTKLIEWLPQNDLLGHPNIKAFLSHGGLNSIFETMYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLNWKTVTESELYEALEKVINDPSYRQRAQRLSEIHKDQPGHPVNRTVYWINYILRHNGAQHLRAAVYSISLYQYFLLDIAFVVLVGAALFYYSLAKLTKFIRKQGKHIWSNDEHSTVNGHYQNGIPNGKHRRNGHIKHE", "length": 537, "header": "tr|F1NH08-1|F1NH08_CHICK Isoform 1 of 2-hydroxyacylsphingosine 1-beta-galactosyltransferase OS=Gallus gallus OX=9031 GN=UGT8 PE=1 SV=3 CANONICAL=F1NH08-1" }, "locus": { "chromosome": "4", "start_pos": 55792787, "end_pos": 55767558, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010008694.1", "url": "https://www.ensembl.org/id/ENSGALT00010008694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005085.1", "url": "https://www.ensembl.org/id/ENSGALP00010005085.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:374033", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374033", "resource": "KEGG Pathway" }, { "id": "R-GGA-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "glycolipid biosynthetic process", "id": "GO:0009247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009247", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "neuron projection morphogenesis", "id": "GO:0048812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "paranodal junction assembly", "id": "GO:0030913", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030913", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "galactosylceramide biosynthetic process", "id": "GO:0006682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006682", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "protein localization to paranode region of axon", "id": "GO:0002175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002175", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" }, { "name": "N-acylsphingosine galactosyltransferase activity", "id": "GO:0003851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003851", "evidence": [ { "database": "UniProtKB", "id": "F1NH08", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13093", "name": "", "equation": "an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NH08-1" ], "evidence": [ { "id": "13093", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13093" } ] }, { "id": "21032", "name": "", "equation": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NH08-1", "A0A8V0Y9N3-1", "A0A8V0ZDF9-1" ], "evidence": [ { "id": "21032", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21032" } ] }, { "id": "43400", "name": "", "equation": "N-(2-hydroxy-hexanoyl)-sphing-4-enine + UDP-alpha-D-galactose = N-(2-hydroxy-hexanoyl)-beta-D-galactosyl-sphing-4-enine + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NH08-1" ], "evidence": [ { "id": "43400", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43400" } ] }, { "id": "43404", "name": "", "equation": "N-(2-hydroxy-hexanoyl)-sphinganine + UDP-alpha-D-galactose = N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganine + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NH08-1" ], "evidence": [ { "id": "43404", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43404" } ] }, { "id": "48344", "name": "", "equation": "an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NH08-1" ], "evidence": [ { "id": "48344", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48344" } ] }, { "id": "R-GGA-6785933", "name": "UGT8 transfers Gal from UDP-Gal to CERA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-1981137" ], "output_participant_list": [ "R-ALL-6785915" ], "enzyme_list": [ "F1NH08-1" ], "evidence": [ { "id": "R-GGA-6785933", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6785933" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1981137", "participant_name": "UDP-Gal [endoplasmic reticulum lumen]", "crossref": [ { "id": "66914", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551104", "database": "ZINC", "url": "" }, { "id": "C00052", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-6785915", "participant_name": "GalCer [endoplasmic reticulum membrane]", "crossref": [ { "id": "36498", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Y9N3", "gene_name": "UGT1A1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A8V0Y9N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9N3" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A8V0Y9N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9N3" } ] } ] }, { "uniprot_ac": "A0A8V0ZDF9", "gene_name": "UGT8L", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "A0A8V0ZDF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF9" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "A0A8V0ZDF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF9" } ] } ] }, { "uniprot_ac": "F1NH08", "gene_name": "UGT8", "activity": [ { "ec_number": "2.4.1.47", "activity": "an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+).", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ] }, { "ec_number": "2.4.1.47", "activity": "", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ] }, { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "F1NH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH08" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NH08-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 537, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NH08-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NH08" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.47", "ec_name": "an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+).", "evidence": [ { "id": "2.4.1.47", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.47" }, { "id": "2.4.1.47", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.47" } ] }, { "ec_number": "2.4.1.17", "ec_name": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "2.4.1.17", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.17" }, { "id": "2.4.1.17", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.17" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 333, "end_pos": 335 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSN9-1", "uniprot_ac": "F1NSN9", "uniprot_id": "F1NSN9_CHICK", "mass": { "chemical_mass": 32158.0, "monoisotopic_mass": 32158.0 }, "refseq": { "ac": "NP_001273153", "name": "E3 ubiquitin-protein ligase MARCHF1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" }, "gene_names": [ { "name": "MARCHF1", "type": "recommended", "evidence": [ { "id": "F1NSN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ] }, { "name": "MARCH1", "type": "synonym", "evidence": [ { "id": "NP_001273153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" } ] }, { "name": "MARCHF1", "type": "synonym", "evidence": [ { "id": "NP_001273153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" } ] }, { "name": "Mar-01", "type": "synonym", "evidence": [ { "id": "NP_001273153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "F1NSN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1NSN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase MARCH1", "type": "synonym", "evidence": [ { "id": "NP_001273153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" } ] }, { "name": "E3 ubiquitin-protein ligase MARCHF1", "type": "synonym", "evidence": [ { "id": "NP_001273153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" } ] }, { "name": "membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase", "type": "synonym", "evidence": [ { "id": "NP_001273153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000071.1. On Oct 31, 2013 this sequence version replaced XP_429957.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001273153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MARCHF1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9", "locus": { "chromosome": "4", "start_pos": 22884608, "end_pos": 23104984, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007980", "url": "https://www.ensembl.org/id/ENSGALG00010007980" } ] } } ], "crossref": [ { "id": "F1NSN9", "url": "https://alphafold.ebi.ac.uk/entry/F1NSN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009520", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16806", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16806", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422420", "url": "https://www.ncbi.nlm.nih.gov/gene/422420", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422420", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422420", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTRYQEC", "url": "https://omabrowser.org/oma/group/RTRYQEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PXZ7", "url": "https://www.orthodb.org/?gene=A0A1D5PXZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQU6", "url": "https://www.orthodb.org/?gene=A0A8V0XQU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XV68", "url": "https://www.orthodb.org/?gene=A0A8V0XV68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XZR5", "url": "https://www.orthodb.org/?gene=A0A8V0XZR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y382", "url": "https://www.orthodb.org/?gene=A0A8V0Y382", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSN9", "url": "https://www.orthodb.org/?gene=F1NSN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001273153", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001273153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PXZ7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PXZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XV68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XV68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XV68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XZR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y382", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y382", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y382-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y382-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSN9-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGWCQAIARNPHRLPNSTRTPEVSGDASHNSTLNDKSPGRSTSRSSNISKASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDDESPLITPCRCTGTLRFVHQACLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIVCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEEKNSSCTQSSDVKDAVVVPVAQTGTNSQLAAEEMTSEVMPV", "length": 287, "header": "tr|F1NSN9-1|F1NSN9_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF1 PE=4 SV=3 CANONICAL=F1NSN9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PXZ7-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#A0A1D5PXZ7-1", "sequence": { "sequence": "MPLQQISVVPARETASNGRSSMGRNKEKSKEVENDKSPGRSTSRSSNISKASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDDESPLITPCRCTGTLRFVHQACLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIVCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEEKNSSCTQSSDVKDAVVVPVAQTGTNSQLAAEEMTSEVMPV", "length": 286, "header": "tr|A0A1D5PXZ7-1|A0A1D5PXZ7_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF1 PE=4 SV=1 CANONICAL=F1NSN9-1" }, "locus": { "chromosome": "4", "start_pos": 23009712, "end_pos": 22888376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019019.1", "url": "https://www.ensembl.org/id/ENSGALT00010019019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010568.1", "url": "https://www.ensembl.org/id/ENSGALP00010010568.1" } ] } }, { "isoform_ac": "A0A8V0XQU6-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#A0A8V0XQU6-1", "sequence": { "sequence": "MLGWCQAIARNPHRLPNSTRTPEVSGDASHNSTLASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDDESPLITPCRCTGTLRFVHQACLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIVCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEEKNSSCTQSSDVKDAVVVPVAQTGTNSQLAAEEMTSEVMPV", "length": 270, "header": "tr|A0A8V0XQU6-1|F1NSN9_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF1 PE=4 SV=1 CANONICAL=F1NSN9-1" }, "locus": { "chromosome": "4", "start_pos": 22968388, "end_pos": 22888376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019027.1", "url": "https://www.ensembl.org/id/ENSGALT00010019027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010576.1", "url": "https://www.ensembl.org/id/ENSGALP00010010576.1" } ] } }, { "isoform_ac": "A0A8V0XV68-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#A0A8V0XV68-1", "sequence": { "sequence": "MPLQQISVVPARETASNGRSSMGRNKEKSKEVEASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDDESPLITPCRCTGTLRFVHQACLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIVCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEEKNSSCTQSSDVKDAVVVPVAQTGTNSQLAAEEMTSEVMPV", "length": 269, "header": "tr|A0A8V0XV68-1|F1NSN9_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF1 PE=4 SV=1 CANONICAL=F1NSN9-1" }, "locus": { "chromosome": "4", "start_pos": 23009712, "end_pos": 22888376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019021.1", "url": "https://www.ensembl.org/id/ENSGALT00010019021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010570.1", "url": "https://www.ensembl.org/id/ENSGALP00010010570.1" } ] } }, { "isoform_ac": "A0A8V0XZR5-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#A0A8V0XZR5-1", "sequence": { "sequence": "MNSSSSSSSSYFNFVIMWQSSKISAMYFMDKDSKLSNLFQQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDDESPLITPCRCTGTLRFVHQACLHQWIKSSDTRCCELCKYDFIMETKLKPLRKVSSNGRFGQNSWWWPLDSQEASSSCTCSVRFMFSCGAG", "length": 166, "header": "tr|A0A8V0XZR5-1|F1NSN9_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF1 PE=4 SV=1 CANONICAL=F1NSN9-1" }, "locus": { "chromosome": "4", "start_pos": 22921656, "end_pos": 22888561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019015.1", "url": "https://www.ensembl.org/id/ENSGALT00010019015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010564.1", "url": "https://www.ensembl.org/id/ENSGALP00010010564.1" } ] } }, { "isoform_ac": "A0A8V0Y382-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#A0A8V0Y382-1", "sequence": { "sequence": "MLGWCQAIARNPHRLPNSTRTPEVSGDASHNSTLNDKSPGRSTSRSSNISKASSPTTGTAPRSQSRLSVCPSTQDICRSTTLHDLSEDELEHATPVMVLTPSNRESGKKQVKRRFRRKRETGDNGEHAEKQGKGKDCRLHPEVAKSSWNASDSSSSSDESQWAQARRRAREKARLSRRGRRNKGSCSNQDGSSNNNAVELVTLETTGKKKQDISDPENPTLNHRRRRIPRFKESQSSASSQEARNSSQKCRKSKEKSYCRDEQPASSCLGHNKDIKDCFAEAGSGSDALAAPDDGAPFGAGPTVTDTAQKPPVLYDDWSDDLEVCRICHCEGDDESPLITPCRCTGTLRFVHQACLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIVCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEEKNSSCTQSSDVKDAVVVPVAQTGTNSQLAAEEMTSEVMPV", "length": 535, "header": "tr|A0A8V0Y382-1|A0A8V0Y382_CHICK Computationally mapped isoform of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF1 PE=4 SV=1 CANONICAL=F1NSN9-1" }, "locus": { "chromosome": "4", "start_pos": 22968388, "end_pos": 22888376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019023.1", "url": "https://www.ensembl.org/id/ENSGALT00010019023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010572.1", "url": "https://www.ensembl.org/id/ENSGALP00010010572.1" } ] } }, { "isoform_ac": "F1NSN9-1", "url": "https://www.uniprot.org/uniprotkb/F1NSN9/entry#F1NSN9-1", "sequence": { "sequence": "MLGWCQAIARNPHRLPNSTRTPEVSGDASHNSTLNDKSPGRSTSRSSNISKASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDDESPLITPCRCTGTLRFVHQACLHQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTTSERRKIVCSVTFHVIAITCVVWSLYVLIDRTAEEIKQGNDNGVLEWPFWTKLVVVAIGFTGGLVFMYVQCKVYVQLWRRLKAYNRVIFVQNCPDTAKKLEEKNSSCTQSSDVKDAVVVPVAQTGTNSQLAAEEMTSEVMPV", "length": 287, "header": "tr|F1NSN9-1|F1NSN9_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=MARCHF1 PE=4 SV=3 CANONICAL=F1NSN9-1" }, "locus": { "chromosome": "4", "start_pos": 22968388, "end_pos": 22888376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019025.1", "url": "https://www.ensembl.org/id/ENSGALT00010019025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010574.1", "url": "https://www.ensembl.org/id/ENSGALP00010010574.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:422420", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422420", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "MHC protein binding", "id": "GO:0042287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042287", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" }, { "name": "antigen processing and presentation of peptide antigen via MHC class II", "id": "GO:0002495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002495", "evidence": [ { "database": "UniProtKB", "id": "F1NSN9", "url": "https://www.uniprot.org/uniprotkb/F1NSN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSW3-1", "uniprot_ac": "F1NSW3", "uniprot_id": "F1NSW3_CHICK", "mass": { "chemical_mass": 101300.0, "monoisotopic_mass": 101300.0 }, "refseq": { "ac": "XP_040511629", "name": "transportin-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511629" }, "gene_names": [ { "name": "TNPO1", "type": "recommended", "evidence": [ { "id": "F1NSW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ] }, { "name": "TNPO1", "type": "synonym", "evidence": [ { "id": "XP_040511629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511629" } ] } ], "protein_names": [ { "name": "Transportin-1", "type": "recommended", "evidence": [ { "id": "F1NSW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSW3/entry#names_and_taxonomy" } ] }, { "name": "Importin beta-2", "type": "synonym", "evidence": [ { "id": "F1NSW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSW3/entry#names_and_taxonomy" } ] }, { "name": "Karyopherin beta-2", "type": "synonym", "evidence": [ { "id": "F1NSW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSW3/entry#names_and_taxonomy" } ] }, { "name": "transportin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040511629", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511629" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040511629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511629" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNPO1", "url": "https://www.uniprot.org/uniprotkb/F1NSW3", "locus": { "chromosome": "Z", "start_pos": 25587927, "end_pos": 25665158, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010186", "url": "https://www.ensembl.org/id/ENSGALG00010010186" } ] } } ], "crossref": [ { "id": "F1NSW3", "url": "https://alphafold.ebi.ac.uk/entry/F1NSW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015014", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015014", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427218", "url": "https://www.ncbi.nlm.nih.gov/gene/427218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y879", "url": "https://www.orthodb.org/?gene=A0A8V0Y879", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCW3", "url": "https://www.orthodb.org/?gene=A0A8V0YCW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSW3", "url": "https://www.orthodb.org/?gene=F1NSW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10527", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10527", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040511629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040511629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y879", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y879", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y879-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y879-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSW3-1", "url": "https://www.uniprot.org/uniprotkb/F1NSW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYEWKPDEQGLQQILQLLKESQSPDTTTQRAVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFHNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPELLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMMHIDAFIENLFALATDEEPEVRKNVCRALVMLLEVRMDRLLPHMISIVEYMLLRTQDQDENVALEACEFWLTLAEQPICKDVLCRHLTKLIPVLVNGMKYSEIDIILLKGDVEEDEAIPDSEQDIRPRFHRSRTVAQKHEEDGIEDRDDDDDEIDDDDAISDWNLRKCSAAALDVLANVFRDELLPHILPLLKELLFHPEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLQRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIHKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLHNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMITVNPNGVFQDFIFFCDAVASWISPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAYYGV", "length": 890, "header": "tr|F1NSW3-1|F1NSW3_CHICK Isoform 1 of Transportin-1 OS=Gallus gallus OX=9031 GN=TNPO1 PE=1 SV=3 CANONICAL=F1NSW3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y879-1", "url": "https://www.uniprot.org/uniprotkb/F1NSW3/entry#A0A8V0Y879-1", "sequence": { "sequence": "MVWVGMEYEWKPDEQGLQQILQLLKESQSPDTTTQRAVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFHNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPELLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMMHIDAFIENLFALATDEEPEVRKNVCRALVMLLEVRMDRLLPHMISIVEYMLLRTQDQDENVALEACEFWLTLAEQPICKDVLCRHLTKLIPVLVNGMKYSEIDIILLKGDVEEDEAIPDSEQDIRPRFHRSRTVAQKHEEDGIEDRDDDDDEIDDDDAISDWNLRKCSAAALDVLANVFRDELLPHILPLLKELLFHPEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLQRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIHKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLHNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMITVNPNGVFQDFIFFCDAVASWISPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAYYGV", "length": 895, "header": "tr|A0A8V0Y879-1|F1NSW3_CHICK Computationally mapped isoform of Transportin-1 OS=Gallus gallus OX=9031 GN=TNPO1 PE=1 SV=1 CANONICAL=F1NSW3-1" }, "locus": { "chromosome": "Z", "start_pos": 25665009, "end_pos": 25591198, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024239.1", "url": "https://www.ensembl.org/id/ENSGALT00010024239.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013798.1", "url": "https://www.ensembl.org/id/ENSGALP00010013798.1" } ] } }, { "isoform_ac": "A0A8V0YCW3-1", "url": "https://www.uniprot.org/uniprotkb/F1NSW3/entry#A0A8V0YCW3-1", "sequence": { "sequence": "MEYEWKPDEQGLQQILQLLKESQSPDTTTQRAVQQVSLAGACAGWGGQGRAEQSRAGRPPRPGRAPDEPTRSLSGLILKNNVKAHFHNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPELLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMMHIDAFIENLFALATDEEPEVRKNVCRALVMLLEVRMDRLLPHMISIVEYMLLRTQDQDENVALEACEFWLTLAEQPICKDVLCRHLTKLIPVLVNGMKYSEIDIILLKGDVEEDEAIPDSEQDIRPRFHRSRTVAQKHEEDGIEDRDDDDDEIDDDDAISDWNLRKCSAAALDVLANVFRDELLPHILPLLKELLFHPEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLQRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIHKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLHNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMITVNPNGVFQDFIFFCDAVASWISPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAYYGV", "length": 896, "header": "tr|A0A8V0YCW3-1|F1NSW3_CHICK Computationally mapped isoform of Transportin-1 OS=Gallus gallus OX=9031 GN=TNPO1 PE=1 SV=1 CANONICAL=F1NSW3-1" }, "locus": { "chromosome": "Z", "start_pos": 25643601, "end_pos": 25591198, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024227.1", "url": "https://www.ensembl.org/id/ENSGALT00010024227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013791.1", "url": "https://www.ensembl.org/id/ENSGALP00010013791.1" } ] } }, { "isoform_ac": "F1NSW3-1", "url": "https://www.uniprot.org/uniprotkb/F1NSW3/entry#F1NSW3-1", "sequence": { "sequence": "MEYEWKPDEQGLQQILQLLKESQSPDTTTQRAVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFHNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPELLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMMHIDAFIENLFALATDEEPEVRKNVCRALVMLLEVRMDRLLPHMISIVEYMLLRTQDQDENVALEACEFWLTLAEQPICKDVLCRHLTKLIPVLVNGMKYSEIDIILLKGDVEEDEAIPDSEQDIRPRFHRSRTVAQKHEEDGIEDRDDDDDEIDDDDAISDWNLRKCSAAALDVLANVFRDELLPHILPLLKELLFHPEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLQRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIHKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLHNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMITVNPNGVFQDFIFFCDAVASWISPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAYYGV", "length": 890, "header": "tr|F1NSW3-1|F1NSW3_CHICK Isoform 1 of Transportin-1 OS=Gallus gallus OX=9031 GN=TNPO1 PE=1 SV=3 CANONICAL=F1NSW3-1" }, "locus": { "chromosome": "Z", "start_pos": 25643601, "end_pos": 25591198, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024236.1", "url": "https://www.ensembl.org/id/ENSGALT00010024236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013796.1", "url": "https://www.ensembl.org/id/ENSGALP00010013796.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" }, { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "F1NSW3", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NSW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSW3" }, { "id": "SM00913", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00913" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Importin N-terminal", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 101, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 727, "end_pos": 729 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NFM3-1", "uniprot_ac": "F1NFM3", "uniprot_id": "F1NFM3_CHICK", "mass": { "chemical_mass": 63527.0, "monoisotopic_mass": 63527.0 }, "refseq": { "ac": "NP_001026272", "name": "myotubularin-related protein 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026272" }, "gene_names": [ { "name": "MTMR9", "type": "recommended", "evidence": [ { "id": "F1NFM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ] }, { "name": "MTMR9", "type": "synonym", "evidence": [ { "id": "NP_001026272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026272" } ] } ], "protein_names": [ { "name": "Myotubularin-related protein 9", "type": "recommended", "evidence": [ { "id": "F1NFM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFM3/entry#names_and_taxonomy" } ] }, { "name": "Inactive phosphatidylinositol 3-phosphatase 9", "type": "synonym", "evidence": [ { "id": "F1NFM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFM3/entry#names_and_taxonomy" } ] }, { "name": "myotubularin-related protein 9", "type": "synonym", "evidence": [ { "id": "NP_001026272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026272" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01004912.1, HAEL01000891.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000070.1. On or before Dec 9, 2020 this sequence version replaced XP_015140615.1, NP_001026272.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001026272", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026272" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTMR9", "url": "https://www.uniprot.org/uniprotkb/F1NFM3", "locus": { "chromosome": "3", "start_pos": 106978406, "end_pos": 106935191, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011967", "url": "https://www.ensembl.org/id/ENSGALG00010011967" } ] } } ], "crossref": [ { "id": "F1NFM3", "url": "https://alphafold.ebi.ac.uk/entry/F1NFM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016649", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016649", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14536", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14536", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422033", "url": "https://www.ncbi.nlm.nih.gov/gene/422033", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422033", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422033", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IEREWIC", "url": "https://omabrowser.org/oma/group/IEREWIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBZ4", "url": "https://www.orthodb.org/?gene=A0A8V0YBZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YD93", "url": "https://www.orthodb.org/?gene=A0A8V0YD93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK82", "url": "https://www.orthodb.org/?gene=A0A8V0YK82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YK87", "url": "https://www.orthodb.org/?gene=A0A8V0YK87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NFM3", "url": "https://www.orthodb.org/?gene=F1NFM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026272", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026272", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YD93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YD93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YK87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NFM3-1", "url": "https://www.uniprot.org/uniprotkb/F1NFM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFAELIKTPRADNVVLHRPFEPAVEGTLCLTGHHLIFSSRRQDNAEELWLLHSNIDSIEKRFVGSLGTIVIKCKDLRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEIVEDGWSAFLPEKEFEFLNALTDEWRLTYINKDFSICPSYPPVVTVPKSIDDETLQKVAVFRHGGRFPVLSYYHKKNGMVMMRTSQPLTGTNGKRCKDDEKLINSTLGPGRRGYIIDTRSLSAAQQARAKGGGFEVEVYYPQWRRIHKSVERFNILQESLIKLVEACNDQSHNMDRWLSKLEASNWLTHVKEILTAGCLAAQCIDREDASVLVHGTEGTDSTLQITSLAQIILDPDCRTIRGFESLIVREWLQAGHPFQQRCAQSAYSNSKQKWEAPVFLLFLDCVWQMLHQFPCSFEFNEHFLVTLFEHAYASQFGTFLGNNENERSKLKLPQKTMSLWSWVNQPEELKNFKNPLFEANSLVIWPSVAPQSLQLWEGVFLRWNRPSKFLDEAQEEMRKIISDNRVLQEKVNYLRRKVAHMETNDEMQEDL", "length": 550, "header": "tr|F1NFM3-1|F1NFM3_CHICK Isoform 1 of Myotubularin-related protein 9 OS=Gallus gallus OX=9031 GN=MTMR9 PE=1 SV=1 CANONICAL=F1NFM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBZ4-1", "url": "https://www.uniprot.org/uniprotkb/F1NFM3/entry#A0A8V0YBZ4-1", "sequence": { "sequence": "MEFAELIKTPRADNVVLHRPFEPAVEGTLCLTGHHLIFSSRRQDNAEELWLLHSNIDSIEKRFVGSLGTIVIKCKDLRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEIVEDGWSAFLPEKEFEFLNALTDEWRLTYINKDFSICPSYPPVVTVPKSIDDETLQKVAVFRHGGRFPVLSYYHKKNGMVMMRTSQPLTGTNGKRCKDDEKLINSTLGPGRRGYIIDTRSLSAAQQARAKGGGFEVEVYYPQWRRIHKSVERFNILQESLIKLVEACNDQSHNMDRWLSKLEASNWLTHVKEILTAGCLAAQCIDREDASVLVHGTEGTDSTLQITSLAQIILDPDCRTIRGFESLIVREWLQAGHPFQQRCAQSAYSNSKQKWEAPVFLLFLDCVWQMLHQFPCSFEFNEHFLVTLFEHAYASQFGTFLGNNENERSKLKLPQKTMSLWSWVNQPEELKNFKNPLFEANSLVIWPSVAPQSLQLWEALGQLLLSVSF", "length": 507, "header": "tr|A0A8V0YBZ4-1|F1NFM3_CHICK Computationally mapped isoform of Myotubularin-related protein 9 OS=Gallus gallus OX=9031 GN=MTMR9 PE=1 SV=1 CANONICAL=F1NFM3-1" }, "locus": { "chromosome": "3", "start_pos": 106978326, "end_pos": 106935346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028666.1", "url": "https://www.ensembl.org/id/ENSGALT00010028666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016477.1", "url": "https://www.ensembl.org/id/ENSGALP00010016477.1" } ] } }, { "isoform_ac": "A0A8V0YD93-1", "url": "https://www.uniprot.org/uniprotkb/F1NFM3/entry#A0A8V0YD93-1", "sequence": { "sequence": "MEFAELIKTPRADNVVLHRPFEPAVEGTLCLTGHHLIFSSRRQDNAEELWLLHSNIDSIEKRFVGSLGTIVIKCKDLRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEIVEDGWSAFLPEKEFEFLNALTDEWRLTYINKDFSICPSYPPVVTVPKSIDDETLQKVAVFRHGGRFPVLSYYHKKNGMVMMRTSQPLTGTNGKRCKDDEKLINSTLGPGRRGYIIDTRSLSAAQQARAKGGGFEVEVYYPQWRRIHKSVERFNILQESLIKLVEACNDQSHNMDRWLSKLEASNWLTHVKEILTAGCLAAQCIDREDASVLVHGTEGTDSTLQITSLAQIILDPDCRTIRGFESLIVREWLQAGHPFQQRCAQSAYSNSKQKWEAPVFLLFLDCVWQMLHQFPCSFEFNEHFLVTLFEHAYASQFGTFLGNNENERSKLKLPQKTMSLWSWVNQPEELKNFKNPLFEANSLVIWPSVAPQSLQLWEGGLLSKLMTIL", "length": 507, "header": "tr|A0A8V0YD93-1|F1NFM3_CHICK Computationally mapped isoform of Myotubularin-related protein 9 OS=Gallus gallus OX=9031 GN=MTMR9 PE=1 SV=1 CANONICAL=F1NFM3-1" }, "locus": { "chromosome": "3", "start_pos": 106963433, "end_pos": 106935346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028653.1", "url": "https://www.ensembl.org/id/ENSGALT00010028653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016465.1", "url": "https://www.ensembl.org/id/ENSGALP00010016465.1" } ] } }, { "isoform_ac": "A0A8V0YK82-1", "url": "https://www.uniprot.org/uniprotkb/F1NFM3/entry#A0A8V0YK82-1", "sequence": { "sequence": "MEFAELIKTPRADNVVLHRPFEPAVEGTLCLTGHHLIFSSRRQDNAEELWLLHSNIDSIEKRFVGSLGTIVIKCKDLRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEIVEDGWSAFLPEKEFEFLNALTDEWRLTYINKDFSICPSYPPVVTVPKSIDDETLQKVAVFRHGGRFPVLSYYHKKNGMVMMRTSQPLTGTNGKRCKDDEKLINSTLGPGRRGYIIDTRSLSAAQQARAKGGGFEVEVYYPQWRRIHKSVERFNILQESLIKLVEACNDQSHNMDRWLSKLEASNWLTHVKEILTAGCLAAQCIDREDASVLVHGTEGTDSTLQITSLAQIILDPDCRTIRGFESLIVREWLQAGHPFQQRCAQSAYSNSKQKWEAPVFLLFLDCVWQMLHQFPCSFEFNEHFLVTLFEHAYASQFGTFLGNNENERSKLKLPQKTMSLWSWVNQPEELKNFKNPLFEANSLVIWPSVAPQSLQLWEGDGRCCSKKKTSYQHTCCLS", "length": 516, "header": "tr|A0A8V0YK82-1|F1NFM3_CHICK Computationally mapped isoform of Myotubularin-related protein 9 OS=Gallus gallus OX=9031 GN=MTMR9 PE=1 SV=1 CANONICAL=F1NFM3-1" }, "locus": { "chromosome": "3", "start_pos": 106973796, "end_pos": 106935346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028657.1", "url": "https://www.ensembl.org/id/ENSGALT00010028657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016469.1", "url": "https://www.ensembl.org/id/ENSGALP00010016469.1" } ] } }, { "isoform_ac": "A0A8V0YK87-1", "url": "https://www.uniprot.org/uniprotkb/F1NFM3/entry#A0A8V0YK87-1", "sequence": { "sequence": "MEFAELIKTPRADNVVLHRPFEPAVEGTLCLTGHHLIFSSRRQDNAEELWLLHSNIDSIEKRFVGSLGTIVIKCKDLRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEIVEDGWSAFLPEKEFEFLNALTDEWRLTYINKDFSICPSYPPVVTVPKSIDDETLQKVAVFRHGGRFPVLSYYHKKNGMVMMRTSQPLTGTNGKRCKDDEKLINSTLGPGRRGYIIDTRSLSAAQQARAKGGGFEVEVYYPQWRRIHKSVERFNILQESLIKLVEACNDQSHNMDRWLSKLEASNWLTHVKEILTAGCLAAQCIDREDASVLVHGTEGTDSTLQITSLAQIILDPDCRTIRGFESLIVREWLQAGHPFQQRCAQSAYSNSKQKWEAPVFLLFLDCVWQMLHQFPCSFEFNEHFLVTLFEHAYASQFGTFLGNNENERSKLKLPQKTMSLWSWVNQPEELKNFKNPLFEANSLVIWPSVAPQSLQLWEGVFLRWNRPSKFLDEAQEEMRKIISDNRVLQEKLWDNSYFLSPFDWLPKEAVSYKLRSALCFCPIAG", "length": 563, "header": "tr|A0A8V0YK87-1|F1NFM3_CHICK Computationally mapped isoform of Myotubularin-related protein 9 OS=Gallus gallus OX=9031 GN=MTMR9 PE=1 SV=1 CANONICAL=F1NFM3-1" }, "locus": { "chromosome": "3", "start_pos": 106978396, "end_pos": 106935346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028663.1", "url": "https://www.ensembl.org/id/ENSGALT00010028663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016474.1", "url": "https://www.ensembl.org/id/ENSGALP00010016474.1" } ] } }, { "isoform_ac": "F1NFM3-1", "url": "https://www.uniprot.org/uniprotkb/F1NFM3/entry#F1NFM3-1", "sequence": { "sequence": "MEFAELIKTPRADNVVLHRPFEPAVEGTLCLTGHHLIFSSRRQDNAEELWLLHSNIDSIEKRFVGSLGTIVIKCKDLRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEIVEDGWSAFLPEKEFEFLNALTDEWRLTYINKDFSICPSYPPVVTVPKSIDDETLQKVAVFRHGGRFPVLSYYHKKNGMVMMRTSQPLTGTNGKRCKDDEKLINSTLGPGRRGYIIDTRSLSAAQQARAKGGGFEVEVYYPQWRRIHKSVERFNILQESLIKLVEACNDQSHNMDRWLSKLEASNWLTHVKEILTAGCLAAQCIDREDASVLVHGTEGTDSTLQITSLAQIILDPDCRTIRGFESLIVREWLQAGHPFQQRCAQSAYSNSKQKWEAPVFLLFLDCVWQMLHQFPCSFEFNEHFLVTLFEHAYASQFGTFLGNNENERSKLKLPQKTMSLWSWVNQPEELKNFKNPLFEANSLVIWPSVAPQSLQLWEGVFLRWNRPSKFLDEAQEEMRKIISDNRVLQEKVNYLRRKVAHMETNDEMQEDL", "length": 550, "header": "tr|F1NFM3-1|F1NFM3_CHICK Isoform 1 of Myotubularin-related protein 9 OS=Gallus gallus OX=9031 GN=MTMR9 PE=1 SV=1 CANONICAL=F1NFM3-1" }, "locus": { "chromosome": "3", "start_pos": 106955350, "end_pos": 106935346, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028643.1", "url": "https://www.ensembl.org/id/ENSGALT00010028643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016458.1", "url": "https://www.ensembl.org/id/ENSGALP00010016458.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422033", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422033", "resource": "KEGG Pathway" }, { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7GQU3-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "Mtmr9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYINKEFTVCPSYPPTVIVPKSIDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYLIDTRSLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHVLQESLIKLVEACNEQTHNMDRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSKQKWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWSRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGLRESP", "length": 549 }, "evidence": [ { "id": "F1NFM3", "url": "https://omabrowser.org/oma/group/F1NFM3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A5G2R4H0-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "MTMR9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGPLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVIVPKAIDDEALRKVAMFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRPLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHILQDSLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCLDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSRQKWESPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 549 }, "evidence": [ { "id": "F1NFM3", "url": "https://omabrowser.org/oma/group/F1NFM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A7MB43-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "MTMR9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGPLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSTISEWRLSYVNKEFSVCPSYPPAVIVPKAIDDDALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRPLNIAQQARAKGGGFEQEAHYPQWRRIHKSIDRYHILQESLIKLVESCNDQTQNMDRWLSKLEASNWLTHIKEILTTACLAAQCLDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNSKQKWESPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNLLRRQLAELETEDGVQESP", "length": 549 }, "evidence": [ { "id": "F1NFM3", "url": "https://omabrowser.org/oma/group/F1NFM3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96QG7-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "MTMR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEANNLVIWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 549 }, "evidence": [ { "id": "F1NFM3", "url": "https://omabrowser.org/oma/group/F1NFM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2D0-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "Mtmr9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYTAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEVIEDGWHSFLPEQEFEFYSSATSEWRLSYINKDFSICPSYPPTVIVPKSVDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYLIDTRSLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHVLQESLIKLVEACNEQTHNMDRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSSKQKWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPGELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWSRSSKYLDEAYEEMVNIIEYNKELQAKVNVLRRQLAELETEDGL", "length": 545 }, "evidence": [ { "id": "F1NFM3", "url": "https://omabrowser.org/oma/group/F1NFM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "regulation of phosphatidylinositol dephosphorylation", "id": "GO:0060304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060304", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein phosphatase binding", "id": "GO:0019903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019903", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "F1NFM3", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NFM3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 550, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NFM3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NFM3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NFM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFM3" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 499, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NMJ6-1", "uniprot_ac": "F1NMJ6", "uniprot_id": "F1NMJ6_CHICK", "mass": { "chemical_mass": 192206.0, "monoisotopic_mass": 192206.0 }, "refseq": { "ac": "XP_003643026", "name": "rapamycin-insensitive companion of mTOR", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643026" }, "gene_names": [ { "name": "RICTOR", "type": "recommended", "evidence": [ { "id": "F1NMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ] }, { "name": "RICTOR", "type": "synonym", "evidence": [ { "id": "XP_003643026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643026" } ] } ], "protein_names": [ { "name": "RPTOR independent companion of MTOR complex 2", "type": "synonym", "evidence": [ { "id": "F1NMJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6/entry#names_and_taxonomy" } ] }, { "name": "rapamycin-insensitive companion of mTOR", "type": "synonym", "evidence": [ { "id": "XP_003643026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643026" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643026" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RICTOR", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6", "locus": { "chromosome": "Z", "start_pos": 12737759, "end_pos": 12818716, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013357", "url": "https://www.ensembl.org/id/ENSGALG00010013357" } ] } } ], "crossref": [ { "id": "ENSGALG00000003775", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003775", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427447", "url": "https://www.ncbi.nlm.nih.gov/gene/427447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427447", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETSMCLL", "url": "https://omabrowser.org/oma/group/ETSMCLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDR8", "url": "https://www.orthodb.org/?gene=A0A8V0YDR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMJ6", "url": "https://www.orthodb.org/?gene=F1NMJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13298", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13298", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13298:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13298:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389357", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5218920", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218920", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6804757", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804757", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9856530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003643026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YDR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSLRARSLRHLRIRGRNDSGEENVPLDLSREPCDNMREILQNVAKLQGVSNMRKLGHLNNFTKLLCNTGHAEEKLGFTYDRIIICLRLALLNEAKEVRAAGLRALRYLIRDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSITNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLSTILKNVIDCQLSRINEALITTVLHLINHPKTRQYVRADVELERILAPYTDFHYRHNPDTAEGQLKEDREARFLASKMGIVAAFRSWAGIISLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVAEEFIEALLSVDPSRFQDCWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALVLSAFITNGLLEGLVEVITSSDDHVSVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIMKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAISTHQKRDQYRVQKDIVILKDTEEALVMNLRDSQVLNHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDYAKAKQLTVVGCQFTEFLLESEEDGQGYLEELVKDIVSWLNSSSGMKPERSLQNNGLLNTLSQHYFLFFGTLSCHPHGVKMLEKCNVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDSCRLYATKHLRVLLRANVEFFSNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQMEKWQKEYNLKYVELIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLESQSIVTDLSYTVRSPMLDKWEGIKQLKAALWALGNIGSSNWGLNLLQEENVIPDIMALAQHCEVLSVRGTCVYVLGLIAKTKQGCDILKLHNWDAVRHSRRQPWPVVPDDMEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSTSTSTFFLDITEDAEQIFYDRPGPSKEKDRSPFPFFSSSRIVKNRILNSLTLPNKKHRSSSDPKGGKLTSSDSKSSLRRNRTVTEPSLDFPSGEEFNPVFRVPKIQTLPTETSMCLLPTKEDTDSTPSIGENDLKLPKGLGNEIHRENTSRERLIGDGTTQTHFKSRSLSFNTDTTTSGISSMSSSPSRETVGVDTTNVDTDCGSLSTVVSTKTVKPSHCSTPQSNHLPLSKSNSVSLVPPGSSHTLPRRAQSLKAPSLATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKSGSLDSRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSNATYGSSDDYIGLALPVDINEIFQVKETPYFQKKTTPPFDDRGARVFAPDAGGLPSGTSDAVKSPFQMLRQQISLTEIMNTSRSDASQFLENTEDTGLQEHTDENCLYCVCIQILGYQPNNKVNSSYNRADFSDIPYPDWCGQAIHNHLDVHSSKFSGISGCSDAVSHGSASSTKSTELVLGVKSIPDDTPVCRILLRKEVLRLVINLSSSVGTKGHETGLLTIKEKYPQAFDDICLYSEVSYLLAHCTFRLPSRRFIQELFQDVQFLQMHEEAEAILAASTKQPVTDVSAES", "length": 1711, "header": "tr|F1NMJ6-1|F1NMJ6_CHICK Isoform 1 of RPTOR independent companion of MTOR complex 2 OS=Gallus gallus OX=9031 GN=RICTOR PE=1 SV=2 CANONICAL=F1NMJ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YDR8-1", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6/entry#A0A8V0YDR8-1", "sequence": { "sequence": "MHTECQHGAWGPRPLLALPEGMPCPQPSSLSYPAPSGRNDSGEENVPLDLSREPCDNMREILQNVAKLQGVSNMRKLGHLNNFTKLLCNTGHAEEKLGFTYDRIIICLRLALLNEAKEVRAAGLRALRYLIRDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSITNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLSTILKNVIDCQLSRINEALITTVLHLINHPKTRQYVRADVELERILAPYTDFHYRHNPDTAEGQLKEDREARFLASKMGIVAAFRSWAGIISLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVAEEFIEALLSVDPSRFQDCWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALVLSAFITNGLLEGLVEVITSSDDHVSVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIMKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAISTHQKRDQYRVQKDIVILKDTEEALVMNLRDSQVLNHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDYAKAKQLTVVGCQFTEFLLESEEDGQGYLEELVKDIVSWLNSSSGMKPERSLQNNGLLNTLSQHYFLFFGTLSCHPHGVKMLEKCNVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDSCRLYATKHLRVLLRANVEFFSNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQMEKWQKEYNLKYVELIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLESQSIVTDLSYTVRSPMLDKWEGIKQLKAALWALGNIGSSNWGLNLLQEENVIPDIMALAQHCEVLSVRGTCVYVLGLIAKTKQGCDILKLHNWDAVRHSRRQPWPVVPDDMEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSTSTSTFFLDITEDAEQIFYDRPGPSKEKDRSPFPFFSSSRIVKNRILNSLTLPNKKHRSSSDPKGGKLTSSDSKSSLRRNRTVTEPSLDFPSGEEFNPVFRVPKIQTLPTETSMCLLPTKEDTDSTPSIGENDLKLPKGLGNEIHRENTSRERLIGDGTTQTHFKSRSLSFNTDTTTSGISSMSSSPSRETVGVDTTNVDTDCGSLSTVVSTKTVKPSHCSTPQSNHLPLSKSNSVSLVPPGSSHTLPRRAQSLKAPSLATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKSGSLDSRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSNATYGSSDDYIGLALPVDINEIFQVKETPYFQKKTTPPFDDRGARVFAPDAGGLPSGTSDAVKSPFQMLRQQISLTEIMNTSRSDASQFLENTEDTGLQEHTDENCLYCVCIQILGYQPNNKVNSSYNRADFSDIPYPDWCGQAIHNHLDVHSSKFSGISGCSDAVSHGSASSTKSTELVLGVKSIPDDTPVCRILLRKEVLRLVINLSSSVGTKGHETGLLTIKEKYPQAFDDICLYSEVSYLLAHCTFRLPSRRFIQELFQDVQFLQMHEEAEAILAASTKQPVTDVSAES", "length": 1731, "header": "tr|A0A8V0YDR8-1|F1NMJ6_CHICK Computationally mapped isoform of RPTOR independent companion of MTOR complex 2 OS=Gallus gallus OX=9031 GN=RICTOR PE=1 SV=1 CANONICAL=F1NMJ6-1" }, "locus": { "chromosome": "Z", "start_pos": 12818690, "end_pos": 12738067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032171.1", "url": "https://www.ensembl.org/id/ENSGALT00010032171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018961.1", "url": "https://www.ensembl.org/id/ENSGALP00010018961.1" } ] } }, { "isoform_ac": "F1NMJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6/entry#F1NMJ6-1", "sequence": { "sequence": "MAVSLRARSLRHLRIRGRNDSGEENVPLDLSREPCDNMREILQNVAKLQGVSNMRKLGHLNNFTKLLCNTGHAEEKLGFTYDRIIICLRLALLNEAKEVRAAGLRALRYLIRDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSITNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLSTILKNVIDCQLSRINEALITTVLHLINHPKTRQYVRADVELERILAPYTDFHYRHNPDTAEGQLKEDREARFLASKMGIVAAFRSWAGIISLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVAEEFIEALLSVDPSRFQDCWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALVLSAFITNGLLEGLVEVITSSDDHVSVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIMKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAISTHQKRDQYRVQKDIVILKDTEEALVMNLRDSQVLNHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDYAKAKQLTVVGCQFTEFLLESEEDGQGYLEELVKDIVSWLNSSSGMKPERSLQNNGLLNTLSQHYFLFFGTLSCHPHGVKMLEKCNVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDSCRLYATKHLRVLLRANVEFFSNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVTKQMEKWQKEYNLKYVELIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPVHLYGQLVHHKTGCHLLESQSIVTDLSYTVRSPMLDKWEGIKQLKAALWALGNIGSSNWGLNLLQEENVIPDIMALAQHCEVLSVRGTCVYVLGLIAKTKQGCDILKLHNWDAVRHSRRQPWPVVPDDMEQLCNELSSIPSTLSLNSESTSSRHNSESESAPSSMFIMEDDRFGSTSTSTFFLDITEDAEQIFYDRPGPSKEKDRSPFPFFSSSRIVKNRILNSLTLPNKKHRSSSDPKGGKLTSSDSKSSLRRNRTVTEPSLDFPSGEEFNPVFRVPKIQTLPTETSMCLLPTKEDTDSTPSIGENDLKLPKGLGNEIHRENTSRERLIGDGTTQTHFKSRSLSFNTDTTTSGISSMSSSPSRETVGVDTTNVDTDCGSLSTVVSTKTVKPSHCSTPQSNHLPLSKSNSVSLVPPGSSHTLPRRAQSLKAPSLATIKSLADYNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKSGSLDSRLTPSRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSNATYGSSDDYIGLALPVDINEIFQVKETPYFQKKTTPPFDDRGARVFAPDAGGLPSGTSDAVKSPFQMLRQQISLTEIMNTSRSDASQFLENTEDTGLQEHTDENCLYCVCIQILGYQPNNKVNSSYNRADFSDIPYPDWCGQAIHNHLDVHSSKFSGISGCSDAVSHGSASSTKSTELVLGVKSIPDDTPVCRILLRKEVLRLVINLSSSVGTKGHETGLLTIKEKYPQAFDDICLYSEVSYLLAHCTFRLPSRRFIQELFQDVQFLQMHEEAEAILAASTKQPVTDVSAES", "length": 1711, "header": "tr|F1NMJ6-1|F1NMJ6_CHICK Isoform 1 of RPTOR independent companion of MTOR complex 2 OS=Gallus gallus OX=9031 GN=RICTOR PE=1 SV=2 CANONICAL=F1NMJ6-1" }, "locus": { "chromosome": "Z", "start_pos": 12813387, "end_pos": 12738067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032157.1", "url": "https://www.ensembl.org/id/ENSGALT00010032157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018947.1", "url": "https://www.ensembl.org/id/ENSGALP00010018947.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427447", "resource": "KEGG Pathway" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates AKT signaling" }, { "id": "R-GGA-389357", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "resource": "Reactome", "description": "CD28 dependent PI3K/Akt signaling" }, { "id": "R-GGA-5218920", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5218920", "resource": "Reactome", "description": "VEGFR2 mediated vascular permeability" }, { "id": "R-GGA-6804757", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804757", "resource": "Reactome", "description": "Regulation of TP53 Degradation" }, { "id": "R-GGA-9856530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856530", "resource": "Reactome", "description": "High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZNG4-1", "protein_name": "RPTOR independent companion of MTOR, complex 2", "gene_name": "Rictor", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAIGRGRSLKNLRIRGRNDSGEENVPLDLTREPSDNLREILQNVAKLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFNYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVANSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTDEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFVLKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYASLDLDFAKSKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKVLTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHKEYNSKYVDLIEEQLNEALTTYRKPIDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQSIITELCQNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHSWDSVRHSRKHLWPVVPDDVEQLCNELSSVPSTLSLNSESTSSRHNSESESAPSSMFILEDDRFGSSSTSTFFLDINEDAEPAFYDRPGPIKDKNSFPFFASSKLVKNRILNSLTLPTKKHRSSSDPKGGKLSSENKTSNRRIRTFTEPSVDFNHSDDFTNISPAQKTLQLETSFVGNKHLEDTGSTPSIGDNDLKFPKSFGPENHRENTSRERLVVESSAGSHMKIRSQSFNTDTTTSGISSMSSSPSRETVAVDSTTMDTDCGSLSTVVSTKTVKTSHYLTPQANHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTIANNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQSKHVPPPDDRGARTFSHDGGGLPSGTGSLVKNSFHLLRQQMSLTEIMNSVHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSSICSHSDLQDIPYSDWCEQPIHNPLEVVPSKFSGISGCSDGASQEEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVVNLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAIPPNQPIVDESAES", "length": 1733 }, "evidence": [ { "id": "F1NMJ6", "url": "https://omabrowser.org/oma/group/F1NMJ6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "embryo development ending in birth or egg hatching", "id": "GO:0009792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009792", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "lipid biosynthetic process", "id": "GO:0008610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008610", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "positive regulation of TOR signaling", "id": "GO:0032008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032008", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "TORC2 signaling", "id": "GO:0038203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038203", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "TOR signaling", "id": "GO:0031929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031929", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "F1NMJ6", "url": "https://www.uniprot.org/uniprotkb/F1NMJ6" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": 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This record is derived from a genomic sequence (NC_052573.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"MERFLGFVKQIRRSRRRKGKKYRPEEDYHEGYEDVYYYASEHFRNESPYTKSANQTRTPDGALSVRRQSIPEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRMKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEATIMSGSTLSLNHENPQPRSQLGRQASFQERSTVRPHYSQASRSNTLPSDVGRKSMVMRKIKQEMKEIMSPTPVELHKVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1154, "header": "tr|F1NHU1-1|F1NHU1_CHICK Isoform 1 of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=4 CANONICAL=F1NHU1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P1Z0-1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1/entry#A0A1D5P1Z0-1", "sequence": { "sequence": "MIAVSFKCRCQILRRLTKDESPYTKSANQTRTPDGALSVRRQSIPEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHAALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRMKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEDKADRRLCLRNMTLLATIMSGSTLSLNHENPQPRSQLGRQASFQERSTVRPHYSQASRSNTLPSDVGRKSMVMRKIKQEMKEIMSPTPVELHKVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1144, "header": "tr|A0A1D5P1Z0-1|A0A1D5P1Z0_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=1 CANONICAL=F1NHU1-1" }, "locus": { "chromosome": "1", "start_pos": 34705789, "end_pos": 34558621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029075.1", "url": "https://www.ensembl.org/id/ENSGALT00010029075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016834.1", "url": "https://www.ensembl.org/id/ENSGALP00010016834.1" } ] } }, { "isoform_ac": "A0A8V0Y818-1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1/entry#A0A8V0Y818-1", "sequence": { "sequence": "MDESPYTKSANQTRTPDGALSVRRQSIPEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHAALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRMKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEATIMSGSTLSLNHENPQPRSQLGRQASFQERSTVRPHYSQASRSNTLPSDVGRKSMVMRKIKQEMKEIMSPTPVELHKVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1112, "header": "tr|A0A8V0Y818-1|F1NHU1_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=1 CANONICAL=F1NHU1-1" }, "locus": { "chromosome": "1", "start_pos": 34672400, "end_pos": 34558621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029069.1", "url": "https://www.ensembl.org/id/ENSGALT00010029069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016828.1", "url": "https://www.ensembl.org/id/ENSGALP00010016828.1" } ] } }, { "isoform_ac": "A0A8V0YEB2-1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1/entry#A0A8V0YEB2-1", "sequence": { "sequence": "MERFLGFVKQIRRSRRRKGKKYRPEEDYHEGYEDVYYYASEHFRNESPYTKSANQTRTPDGALSVRRQSIPEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHVSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEATIMSGSTLSLNHENPQPRSQLGRQASFQERSTVRPHYSQASRSNTLPSDVGRKSMVMRKIKQEMKEIMSPTPVELHKVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1103, "header": "tr|A0A8V0YEB2-1|F1NHU1_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=1 CANONICAL=F1NHU1-1" }, "locus": { "chromosome": "1", "start_pos": 34768104, "end_pos": 34558621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029079.1", "url": "https://www.ensembl.org/id/ENSGALT00010029079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016838.1", "url": "https://www.ensembl.org/id/ENSGALP00010016838.1" } ] } }, { "isoform_ac": "A0A8V0YEB7-1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1/entry#A0A8V0YEB7-1", "sequence": { "sequence": "MPGWKKNIPICLQAEQERDESPYTKSANQTRTPDGALSVRRQSIPEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHAALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRMKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEATIMSGSTLSLNHENPQPRSQLGRQASFQERSTVRPHYSQASRSNTLPSDVGRKSMVMRKIKQEMKEIMSPTPVELHKVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1129, "header": "tr|A0A8V0YEB7-1|F1NHU1_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=1 CANONICAL=F1NHU1-1" }, "locus": { "chromosome": "1", "start_pos": 34864095, "end_pos": 34558621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029085.1", "url": "https://www.ensembl.org/id/ENSGALT00010029085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016844.1", "url": "https://www.ensembl.org/id/ENSGALP00010016844.1" } ] } }, { "isoform_ac": "A0A8V0YL75-1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1/entry#A0A8V0YL75-1", "sequence": { "sequence": "MSPSPGRGGIPQPRATEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRMKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEATIMSGSTLSLNHENPQPRSQLGRQASFQERSTVRPHYSQASRSNTLPSDVGRKSMVMRKIKQEMKEIMSPTPVELHKVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1099, "header": "tr|A0A8V0YL75-1|F1NHU1_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=1 CANONICAL=F1NHU1-1" }, "locus": { "chromosome": "1", "start_pos": 34636569, "end_pos": 34558621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029065.1", "url": "https://www.ensembl.org/id/ENSGALT00010029065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016824.1", "url": "https://www.ensembl.org/id/ENSGALP00010016824.1" } ] } }, { "isoform_ac": "A0A8V0YL84-1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1/entry#A0A8V0YL84-1", "sequence": { "sequence": "MIAVSFKCRCQILRRLTKDESPYTKSANQTRTPDGALSVRRQSIPEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRMKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1050, "header": "tr|A0A8V0YL84-1|F1NHU1_CHICK Computationally mapped isoform of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=1 CANONICAL=F1NHU1-1" }, "locus": { "chromosome": "1", "start_pos": 34705789, "end_pos": 34558621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029078.1", "url": "https://www.ensembl.org/id/ENSGALT00010029078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016837.1", "url": "https://www.ensembl.org/id/ENSGALP00010016837.1" } ] } }, { "isoform_ac": "F1NHU1-1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1/entry#F1NHU1-1", "sequence": { "sequence": "MERFLGFVKQIRRSRRRKGKKYRPEEDYHEGYEDVYYYASEHFRNESPYTKSANQTRTPDGALSVRRQSIPEEFKGSTIVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKSVNGINLTKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGTGVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLVEYDVSVMDSVSTASGPLLVEVAKTPGAALGVALSTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANAADNVKLEILPHHQTRLALKGPEHALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRMKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPIVGFGIQLQGSVFATETLSSPPLISYIESDSPAERCGVLQIGDRIVAINGIPTEDSTFDEANQLLRDSSITNKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQHCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDATSPKKFSVPVGHITELSDAEDETSAAQKSGKLSDIYSATVPSVDSAVESWDGSGIDTSFGNQGPSYQASGYNFNAYEWRSPKQRGSLSPPSRPRNHPFHDTVLSDDEWDRPTASSTVSKNMWQQKETETLGENQENHLKQTSVERSGGENIRSMKKEGKLWKGVSGGQRKGGGQLEEWNTSSFAGTHDNTEADQEENFWSQALEDLETCGQSGILRELEATIMSGSTLSLNHENPQPRSQLGRQASFQERSTVRPHYSQASRSNTLPSDVGRKSMVMRKIKQEMKEIMSPTPVELHKVTLYKDSDGEDFGFSVSDGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLELVISRNPLASQKGSSDQQPSASGEWSDQNNAFLQQTEHGNMNTETRDPTNTL", "length": 1154, "header": "tr|F1NHU1-1|F1NHU1_CHICK Isoform 1 of Glutamate receptor interacting protein 1 OS=Gallus gallus OX=9031 GN=GRIP1 PE=4 SV=4 CANONICAL=F1NHU1-1" }, "locus": { "chromosome": "1", "start_pos": 34768104, "end_pos": 34558621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029082.1", "url": "https://www.ensembl.org/id/ENSGALT00010029082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016840.1", "url": "https://www.ensembl.org/id/ENSGALP00010016840.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-416993", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416993", "resource": "Reactome", "description": "Trafficking of GluR2-containing AMPA receptors" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NHU1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "F1NHU1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "id": "GO:0098887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098887", "evidence": [ { "database": "UniProtKB", "id": "F1NHU1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "F1NHU1", "url": "https://www.uniprot.org/uniprotkb/F1NHU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 909, "end_pos": 911, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NHU1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1154, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NHU1-F1.pdb", "url_external": 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"method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NUE4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NUE4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 260, "end_pos": 262 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3Z6-1", "uniprot_ac": "E1C3Z6", "uniprot_id": "E1C3Z6_CHICK", "mass": { "chemical_mass": 52059.0, "monoisotopic_mass": 52059.0 }, "refseq": { "ac": "XP_419778", "name": "5'-nucleotidase domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419778" }, "gene_names": [ { "name": "NT5DC1", "type": "recommended", "evidence": [ { "id": "E1C3Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6" } ] }, { "name": "NT5DC1", "type": "synonym", "evidence": [ { "id": "XP_419778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419778" } ] } ], "protein_names": [ { "name": "5'-nucleotidase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "E1C3Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6/entry#names_and_taxonomy" } ] }, { "name": "5'-nucleotidase domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419778" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419778" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3Z6", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NT5DC1", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6", "locus": { "chromosome": "3", "start_pos": 63601640, "end_pos": 63727019, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012690", "url": "https://www.ensembl.org/id/ENSGALG00010012690" } ] } } ], "crossref": [ { "id": "E1C3Z6", "url": "https://alphafold.ebi.ac.uk/entry/E1C3Z6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014964", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014964", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421746", "url": "https://www.ncbi.nlm.nih.gov/gene/421746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ICSNPYG", "url": "https://omabrowser.org/oma/group/ICSNPYG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PPC4", "url": "https://www.orthodb.org/?gene=A0A1D5PPC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFD1", "url": "https://www.orthodb.org/?gene=A0A8V0YFD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3Z6", "url": "https://www.orthodb.org/?gene=E1C3Z6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12103:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12103:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05761", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05761", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PPC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PPC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Z6", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Z6-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQYFSLADCEVMGFDLDHTLCRYHLPQSAALIYDSFAQYLVTEKGYDKDLLTLNPESLDFCCKGLALDLEDGNFLKLAEDGTVLRASHGTRSMTSEEILEIYGRREWKHFSTVSGMLSRSAKYYLYDNYFDLPGALLCARVVDSLDQHDGQKKYDFWKDMVAAIQHNYKISAFKEDCGTYFPEVKNHPEKYLQRCPSSVKKWLKQLKSAGKILLLITSSHSDYCRLLCEYILGNDFEEYFDVVITNALKPGFFSHTPNQRPFRTLENDEEQEALLSLDKPGWYSQGNAIHLYELLKKMTGKLDPKVVYFGDSMHSDIFPARHYSNWETVFILEELLGDKVMVPTETESEPLEKKGKYEGYQPKIPYSVSEQWGSFFVDRLPGLENAEETLVRTWSCKCISTYSTIAIPSLEAIADLPLDYRFTRFSSNSSATAGYYPSPPRALLPSEESVTMK", "length": 454, "header": "tr|E1C3Z6-1|E1C3Z6_CHICK Isoform 1 of 5'-nucleotidase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=NT5DC1 PE=1 SV=1 CANONICAL=E1C3Z6-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PPC4-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6/entry#A0A1D5PPC4-1", "sequence": { "sequence": "MQQYFSLADCEVMGFDLDHTLCRYHLPQSAALIYDSFAQYLVTEKGYDKDLLTLNPESLDFCCKGLALDLEDGNFLKLAEDGTVLRASHGTRSMTSEEILEIYGRREWKHFSTVSGMLSRSAKYYLYDNYFDLPGALLCARVVDSLDQHDGQKKYDFWKDMVAAIQHNYKISAFKEDCGTYFPEVKNHPEKYLQRCPSSVKKWLKQLKSAGKILLLITSSHSDYCRLLCEYILGNDFEEYFDVVITNALKPGFFSHTPNQRPFRTLENDEEQEALLSLDKPGWYSQGNAIHLYELLKKMTGKLDPKVVYFGDSMHSDIFPARHYSNWETVFILEELLGDKVMVPTETESEPLEKKGKYEGYQPKIPYSVSEQWGSFFVDRLPGLENAEETLVRTWSCKCISTYSTIAIPSLEAIAGL", "length": 417, "header": "tr|A0A1D5PPC4-1|A0A1D5PPC4_CHICK Computationally mapped isoform of 5'-nucleotidase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=NT5DC1 PE=1 SV=2 CANONICAL=E1C3Z6-1" }, "locus": { "chromosome": "3", "start_pos": 63726966, "end_pos": 63614636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030358.1", "url": "https://www.ensembl.org/id/ENSGALT00010030358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017610.1", "url": "https://www.ensembl.org/id/ENSGALP00010017610.1" } ] } }, { "isoform_ac": "A0A8V0YFD1-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6/entry#A0A8V0YFD1-1", "sequence": { "sequence": "MQQYFSLADCEVMGFDLDHTLCRYHLPQSAALIYDSFAQYLVTEKGYDKDLLTLNPESLDFCCKGLALDLEDGNFLKLAEDGTVLRASHGTRSMTSEEILEIYGRREWKHFSTVSGMLSRSAKYYLYDNYFDLPGALLCARVVDSLDQHDGQKKYDFWKDMVAAIQHNYKISAFKEDCGTYFPEVKNHPEKYLQRCPSSVKKWLKQLKSAGKILLLITSSHSDYCRLLCEYILGNDFEEYFDVVITNALKPGFFSHTPNQRPFRTLENDEEQEALLSLDKPGWYSQGNAIHLYELLKKMTGKLDPKVVYFGDSMHSDIFPARHYSNWETVFILEELLGDKVMVPTETESEPLEKKGKYEGYQPKIPYSVSEQWGSFFVDRLPGLENAEETLVRTWSCKCISTYSTIAIPSLEAIAEHF", "length": 418, "header": "tr|A0A8V0YFD1-1|E1C3Z6_CHICK Computationally mapped isoform of 5'-nucleotidase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=NT5DC1 PE=1 SV=1 CANONICAL=E1C3Z6-1" }, "locus": { "chromosome": "3", "start_pos": 63726966, "end_pos": 63601914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030360.1", "url": "https://www.ensembl.org/id/ENSGALT00010030360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017612.1", "url": "https://www.ensembl.org/id/ENSGALP00010017612.1" } ] } }, { "isoform_ac": "E1C3Z6-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6/entry#E1C3Z6-1", "sequence": { "sequence": "MQQYFSLADCEVMGFDLDHTLCRYHLPQSAALIYDSFAQYLVTEKGYDKDLLTLNPESLDFCCKGLALDLEDGNFLKLAEDGTVLRASHGTRSMTSEEILEIYGRREWKHFSTVSGMLSRSAKYYLYDNYFDLPGALLCARVVDSLDQHDGQKKYDFWKDMVAAIQHNYKISAFKEDCGTYFPEVKNHPEKYLQRCPSSVKKWLKQLKSAGKILLLITSSHSDYCRLLCEYILGNDFEEYFDVVITNALKPGFFSHTPNQRPFRTLENDEEQEALLSLDKPGWYSQGNAIHLYELLKKMTGKLDPKVVYFGDSMHSDIFPARHYSNWETVFILEELLGDKVMVPTETESEPLEKKGKYEGYQPKIPYSVSEQWGSFFVDRLPGLENAEETLVRTWSCKCISTYSTIAIPSLEAIADLPLDYRFTRFSSNSSATAGYYPSPPRALLPSEESVTMK", "length": 454, "header": "tr|E1C3Z6-1|E1C3Z6_CHICK Isoform 1 of 5'-nucleotidase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=NT5DC1 PE=1 SV=1 CANONICAL=E1C3Z6-1" }, "locus": { "chromosome": "3", "start_pos": 63726966, "end_pos": 63607041, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030354.1", "url": "https://www.ensembl.org/id/ENSGALT00010030354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017606.1", "url": "https://www.ensembl.org/id/ENSGALP00010017606.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "B1WC66-1", "protein_name": "5'-nucleotidase domain-containing protein 1", "gene_name": "Nt5dc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQHFSLAACDVVGFDLDHTLCRYNLSESAALIYNSFAQFLVKEKGYDEELLTLTLEDWDFCCKGLALDLEDGTFIKLAADGTVLRASHGTKMMTPEALTEAYGKKEWRHCLSDKRSVSGSDIPCCSGKCYFYDNYFDLPGALLCAKVVDSLTKQNRGQKTFDFWKDVVAGIQHNFKMSAFKENCGFFFPEIKRNLGKYVYRCPESVKKWLQQIKDAGKITMLITSSHSDYCKLLGSYILGKDFADLFDIVITNALKPGFFSHFPSQRSFYTLENDEEKDELPSLDKPGWYSQGNAVHLYELLKKMTSKLEPKVVYFGDSMHSDIFPAHHYTNWETVLILEELQGQEMEKPEEAEPLEKRGKYEGPKVKPLNCLSNKWGSYFIDSVSRRGNAEDSLVYTWSSKRISTYSTIAIPNIESIAELPLDYKFTRFSANNSKTAGYYPLVHYTLASQNTDSKIIST", "length": 461 }, "evidence": [ { "id": "E1C3Z6", "url": "https://omabrowser.org/oma/group/E1C3Z6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7GPB8-1", "protein_name": "5'-nucleotidase domain-containing protein 1", "gene_name": "NT5DC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQHFSLAACDVVGFDLDHTLCRYNLPESARLIYNSFAQFLVREKGYDKELLTVTPEDWDFCCKGLALDLEDGNFIKLADNGTVLRASHGTKMLTPEALEEEYGQKEWKHFLSDSGTACRSGKYYFYDNYFDLPGALLCARVVDSLTKQNSGQKPFDFWKDIVAGIQHNYKMSAFKENCGIYFPEIKRDPGRYLHTCPESVKKWLRQLKNAGKILMLITSSHSDYCRLLCRYILGNDFEDLFDIVITNALKPGFFSHLPSQRPFRTLENDEEQEALPSLDKPGWYSQGNAVHLYELLKKMTGQPEPKVVYFGDSMHSDIFPASHYSNWETVLILEELRGDRDGKPEDAEPLEKKGKYEGPKAKPLNALSKKWGSFFIDSVSGLENTKDSLVYTWSCKRISAYSTIAIPSIEAIAELPLDYKFTRFSSNNSKTAGYYPNPPLVLLNDGMLTAK", "length": 452 }, "evidence": [ { "id": "E1C3Z6", "url": "https://omabrowser.org/oma/group/E1C3Z6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2TBU5-1", "protein_name": "5'-nucleotidase domain-containing protein 1", "gene_name": "NT5DC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQHFSLAACDVVGFDLDHTLCCYNLPESARLIYNSFAQFLVKEKGYDKGLLTVTPEDWDFCCKGLALDLEDGNFIKLADNGTVLRASHGTKMLSAEALAEEFGRKEWKHFMPDTGMAFRSGKYYFYDNYFDLPGALLCARVVDSLTKQNNGQKPFDFWKDIVAGIQHNYKMSAFKENCGIYFPEIKRDPGKYLHTCPESVKKWLRQLKNAGKILMLITSSHSDYCRLLCQYILGNDFEDLFDIVITNALKPGFFSHLPSQRPFRTLENDEEREALPFLDKPGWYSQGNAVHLYELLKKMTGKPEPKVVYFGDSMHSDIFPACHYSNWETVLILEELRGDKDGKPEESEPEEKKGKYEGSKAKPLNTSSKKWGSFFIDSVSGLENREDSLVYTWSCKRISAYSTIAIPSIEAIAELPLDYKFTRFSSNNSKTAGYYPNPPLVLSNAGKLTAK", "length": 452 }, "evidence": [ { "id": "E1C3Z6", "url": "https://omabrowser.org/oma/group/E1C3Z6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54JY6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKIEEIINTEIKLHQQFKNVNVIGFDMDMAIVRYNNNETATLIYECVLEHLVTVFPFLKESKLDFSFSKRGLVIDLELGLILKLDNKKRVIKAFRGKSIVSKEEIDSIYHDEKVIGSESPLKDYDGSNSARFFTMISFFETPITSVIRDFMEYQNSESIRLGKPIDYSTFKQLAKEISISFAKHFNDFTTGHYYTSFKKDPSKYIYKVSNRLKNWLMEIRSKNNTKVILITNSKSEYCHSVMEYSFGENFRDYFDCIIVDAKKPEFFKSDINSKPFTKLMTFYPKEKSDYIECSNIELGVSHDTIFKGGNIHLVLNKLKDHFKKDQISFCYVGDNLIGDVVAPKQVKLMTVAIIEEIQDPDEIIILKREKNTKSQEVQVNSEGLVERSTGKTNYVWGSFFHIHDDHENLSIDTFWSSILRDNADIVVYGVDTLVEYYYQDKFDNKDTLSPCAVVYGGY", "length": 459 }, "evidence": [ { "id": "E1C3Z6", "url": "https://omabrowser.org/oma/group/E1C3Z6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5TFE4-1", "protein_name": "5'-nucleotidase domain-containing protein 1", "gene_name": "NT5DC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQHFSLAACDVVGFDLDHTLCRYNLPESAPLIYNSFAQFLVKEKGYDKELLNVTPEDWDFCCKGLALDLEDGNFLKLANNGTVLRASHGTKMMTPEVLAEAYGKKEWKHFLSDTGMACRSGKYYFYDNYFDLPGALLCARVVDYLTKLNNGQKTFDFWKDIVAAIQHNYKMSAFKENCGIYFPEIKRDPGRYLHSCPESVKKWLRQLKNAGKILLLITSSHSDYCRLLCEYILGNDFTDLFDIVITNALKPGFFSHLPSQRPFRTLENDEEQEALPSLDKPGWYSQGNAVHLYELLKKMTGKPEPKVVYFGDSMHSDIFPARHYSNWETVLILEELRGDEGTRSQRPEESEPLEKKGKYEGPKAKPLNTSSKKWGSFFIDSVLGLENTEDSLVYTWSCKRISTYSTIAIPSIEAIAELPLDYKFTRFSSSNSKTAGYYPNPPLVLSSDETLISK", "length": 455 }, "evidence": [ { "id": "E1C3Z6", "url": "https://omabrowser.org/oma/group/E1C3Z6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C5P5-1", "protein_name": "5'-nucleotidase domain-containing protein 1", "gene_name": "Nt5dc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQHFSLGACDVVGFDLDHTLCRYNLPESARLIYNSFAQFLVKEKGYDEGLLTLTPEDWDFCCKGLALDLEDGTFIKLAADGTVLRASHGTKMMTPEALTEAFGKKEWRHCVSDKRCTSDKPGVSDIPCCSGKCYFYDNYFDLPGALLCARVVDSLTKQNRGQKTFDFWKDVVAGIQHNFKMSAFKENCGFFFPEIKRNLGKYVHRCPESVRKWLRQLKDAGKITMLITSSHSDYCKLLGSYILGEDFADLFDIVITNALKPGFFSHFPSQRPFYTLENDEEKDELPSLDKPGWYSQGNAAHLYELLKKMTSKPEPKVVYFGDSMHSDIFPAHHYTNWETVLILEELQGPEMEKPEEAEPLEKRGKYEAPMVKPLNTLSNKWGSYFIDSVSGRGRAEDSVVYTWSSKRISTYSTIAIPNIESIAELPLDYKFTRFSTNNSKMAGYYPLVHHTLGSQDTDSKIISTEK", "length": 467 }, "evidence": [ { "id": "E1C3Z6", "url": "https://omabrowser.org/oma/group/E1C3Z6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1C3Z6", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1C3Z6", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "E1C3Z6", "url": "https://www.uniprot.org/uniprotkb/E1C3Z6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C3Z6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 454, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C3Z6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C3Z6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 429, "end_pos": 431 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NGZ2-1", "uniprot_ac": "F1NGZ2", "uniprot_id": "F1NGZ2_CHICK", "mass": { "chemical_mass": 128615.0, "monoisotopic_mass": 128615.0 }, "refseq": { "ac": "XP_015134126", "name": "TBC1 domain family member 8B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134126" }, "gene_names": [ { "name": "TBC1D8B", "type": "recommended", "evidence": [ { "id": "F1NGZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2" } ] }, { "name": "TBC1D8B", "type": "synonym", "evidence": [ { "id": "XP_015134126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134126" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 8B", "type": "recommended", "evidence": [ { "id": "F1NGZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 8B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134126" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134126" } ] }, { "annotation": "Involved in vesicular recycling, probably as a RAB11B GTPase-activating protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YFF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF0#function" }, { "database": "UniProtKB", "id": "ARBA00055097", "url": "https://www.uniprot.org/uniprotkb/ARBA00055097#function" }, { "database": "UniProtKB", "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TBC1D8B", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2", "locus": { "chromosome": "4", "start_pos": 17355389, "end_pos": 17323672, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012706", "url": "https://www.ensembl.org/id/ENSGALG00010012706" } ] } } ], "crossref": [ { "id": "F1NGZ2", "url": "https://alphafold.ebi.ac.uk/entry/F1NGZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009040", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009040", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13350", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13350", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13352", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13352", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422383", "url": "https://www.ncbi.nlm.nih.gov/gene/422383", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422383", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422383", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYYTEVV", "url": "https://omabrowser.org/oma/group/GYYTEVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YFF0", "url": "https://www.orthodb.org/?gene=A0A8V0YFF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGZ2", "url": "https://www.orthodb.org/?gene=F1NGZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YFF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGZ2-1", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLKPEEVLLKNALKLWVLERSNQYFVLQRRRGYGEEGGGGLAGLLVGTLDAVLDSTSKVAPFRILHQTPDSQVYWSIACGASREEITEHWDWLEHNVMNILSVFDSNEDITSFVQGKIRGLIAEEGKGSFTKEEDPEKFREGLMKFERCFGLPEQEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGAEIKLIISWDAISKLEKTSNVILTESIHVCSHGEDHYFSMFLHINETFLLMEQLANYAVRRLFDKETFENDLVLHDPLQITKRGLESRAHSQQFSAFFRLPKEETLKEVHECFLWVPFTHYNAHGKMCISENYICFASQDGSLCSVIIPLREVIGVDKADPANRGVNISTKGKRAFRFTEVRDFEQLVTKLRIKCNATSTSSPQHINTEVASSSASDSPKDFDEVPSKIDLRDNSKTVSTEALMTVYHPQDAENLDPKMLKEKMKEQSWNILFFERGHGVSMFRTKKTRDLVVRGIPEALRGELWLLFSGAVNDMASSPGYYTELVEKSLGTCTLATDEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPQIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRVHLPQLTDHMMGMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAVLEYNMDKLLACKDDAEAVTVLNRFFDSVTNKDSPLPPAVQQGSNLSDAKGDHPKVDITDLIRESNERYGDIRYEDVESMRCRNRLYVIQTLETTTKQNVLRVVSQDVKFSPNVLDELYELFKKEHFLSCYWNVNSPVLQHHDASLPYLEQYRIDCQQFRVLCHLLSPWSHCANRDSIALWTFRLLDENCHGLINFKQFSCVLDTMYNGSFTDKLKLLFKLHIPPAFTEVESLSPSKGVALSKEELIHFSQLSVSSAGDSLESDALKSSPEKGKGKVDIQAYLKQWQDELLKKEENIKDLPRMNQSQFIQFSKTLYNLFHGDPEEELLYRAIAVVTSLLLKMEEVGRRLQSPTSPVRSPAATTEVSAESPQKGQEEGSSEQTEGSGAQSLRKNHEWSFAFEQILASLLNEPAFVRFFEKPHEIKTRIESAKNLQLKARTRV", "length": 1126, "header": "tr|F1NGZ2-1|F1NGZ2_CHICK Isoform 1 of TBC1 domain family member 8B OS=Gallus gallus OX=9031 GN=TBC1D8B PE=1 SV=3 CANONICAL=F1NGZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YFF0-1", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2/entry#A0A8V0YFF0-1", "sequence": { "sequence": "MASGASREEITEHWDWLEHNVMNILSVFDSNEDITSFVQGKIRGLIAEEGKGSFTKEEDPEKFREGLMKFERCFGLPEQEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGAEIKLIISWDAISKLEKTSNVILTESIHVCSHGEDHYFSMFLHINETFLLMEQLANYAVRRLFDKETFENDLVLHDPLQITKRGLESRAHSQQFSAFFRLPKEETLKEVHECFLWVPFTHYNAHGKMCISENYICFASQDGSLCSVIIPLREVIGVDKADPANRGVNISTKGKRAFRFTEVRDFEQLVTKLRIKCNATSTSSPQHINTEVASSSASDSPKDFDEVPSKIDLRDNSKTVSTEALMTVYHPQDAENLDPKMLKEKMKEQSWNILFFERGHGVSMFRTKKTRDLVVRGIPEALRGELWLLFSGAVNDMASSPGYYTELVEKSLGTCTLATDEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPQIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRVHLPQLTDHMMGMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAVLEYNMDKLLACKDDAEAVTVLNRFFDSVTNKDSPLPPAVQQGSNLSDAKGDHPKVDITDLIRESNERYGDIRYEDVESMRCRNRLYVIQTLETTTKQNVLRVVSQDVKFSPNVLDELYELFKKEHFLSCYWNVNSPVLQHHDASLPYLEQYRIDCQQFRVLCHLLSPWSHCANRDSIALWTFRLLDENCHGLINFKQFSCVLDTMYNGSFTDKLKLLFKLHIPPAFTEVESLSPSKGVALSKEELIHFSQLSVSSAGDSLESDALKSSPEKGKGKVDIQAYLKQWQDELLKKEENIKDLPRMNQSQFIQFSKTLYNLFHGDPEEELLYRAIAVVTSLLLKMEEVGRRLQSPTSPVRSPAATTEVSAESPQKGQEEGSSEQTEGSGAQSLRKNHEWSFAFEQILASLLNEPAFVRFFEKPHEIKTRIESAKNLQLKARTRV", "length": 1049, "header": "tr|A0A8V0YFF0-1|F1NGZ2_CHICK Computationally mapped isoform of TBC1 domain family member 8B OS=Gallus gallus OX=9031 GN=TBC1D8B PE=1 SV=1 CANONICAL=F1NGZ2-1" }, "locus": { "chromosome": "4", "start_pos": 17355221, "end_pos": 17333525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030393.1", "url": "https://www.ensembl.org/id/ENSGALT00010030393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017628.1", "url": "https://www.ensembl.org/id/ENSGALP00010017628.1" } ] } }, { "isoform_ac": "F1NGZ2-1", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2/entry#F1NGZ2-1", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVLERSNQYFVLQRRRGYGEEGGGGLAGLLVGTLDAVLDSTSKVAPFRILHQTPDSQVYWSIACGASREEITEHWDWLEHNVMNILSVFDSNEDITSFVQGKIRGLIAEEGKGSFTKEEDPEKFREGLMKFERCFGLPEQEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGAEIKLIISWDAISKLEKTSNVILTESIHVCSHGEDHYFSMFLHINETFLLMEQLANYAVRRLFDKETFENDLVLHDPLQITKRGLESRAHSQQFSAFFRLPKEETLKEVHECFLWVPFTHYNAHGKMCISENYICFASQDGSLCSVIIPLREVIGVDKADPANRGVNISTKGKRAFRFTEVRDFEQLVTKLRIKCNATSTSSPQHINTEVASSSASDSPKDFDEVPSKIDLRDNSKTVSTEALMTVYHPQDAENLDPKMLKEKMKEQSWNILFFERGHGVSMFRTKKTRDLVVRGIPEALRGELWLLFSGAVNDMASSPGYYTELVEKSLGTCTLATDEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPQIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRVHLPQLTDHMMGMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAVLEYNMDKLLACKDDAEAVTVLNRFFDSVTNKDSPLPPAVQQGSNLSDAKGDHPKVDITDLIRESNERYGDIRYEDVESMRCRNRLYVIQTLETTTKQNVLRVVSQDVKFSPNVLDELYELFKKEHFLSCYWNVNSPVLQHHDASLPYLEQYRIDCQQFRVLCHLLSPWSHCANRDSIALWTFRLLDENCHGLINFKQFSCVLDTMYNGSFTDKLKLLFKLHIPPAFTEVESLSPSKGVALSKEELIHFSQLSVSSAGDSLESDALKSSPEKGKGKVDIQAYLKQWQDELLKKEENIKDLPRMNQSQFIQFSKTLYNLFHGDPEEELLYRAIAVVTSLLLKMEEVGRRLQSPTSPVRSPAATTEVSAESPQKGQEEGSSEQTEGSGAQSLRKNHEWSFAFEQILASLLNEPAFVRFFEKPHEIKTRIESAKNLQLKARTRV", "length": 1126, "header": "tr|F1NGZ2-1|F1NGZ2_CHICK Isoform 1 of TBC1 domain family member 8B OS=Gallus gallus OX=9031 GN=TBC1D8B PE=1 SV=3 CANONICAL=F1NGZ2-1" }, "locus": { "chromosome": "4", "start_pos": 17355221, "end_pos": 17323780, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030397.1", "url": "https://www.ensembl.org/id/ENSGALT00010030397.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017630.1", "url": "https://www.ensembl.org/id/ENSGALP00010017630.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422383", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422383", "resource": "KEGG Pathway" }, { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9M5-1", "protein_name": "TBC1 domain family member 8B", "gene_name": "Tbc1d8b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLKPEEVLLKNALKLWLMERSNEYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKQSFAKEDDPEKFREALLKFEKSFGLPEQEKLVTYYSCSYWRGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDAISKLEKTSSVIVAESIHVCSQGENHYFSMFLHINETYLLMEQLTNYAIKRLFDKETFDNDPVLDDPLQITKRGLEYRAHSEQFKAFFRLPKEETLKEVHECFLWVPFSHFSTHGKMCISENYICFASQDGNLCSVIIPLREVLAVDKTDDSSRSVIISIKGKTAFRFNEVKDFEQLVAKLRLKCRAASTQDDGSTEVAISSDSTGLSENFEEQPLTFPKECSKTVNTEALMTVFHPQNLENLDSKMLKEKMKEQSWNILFSECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMAANPGYYAEVVEQSLGTSNLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGKNKCALVDQAVFEELIRDHLPQLTDHMTDMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVINKDSPLPSNVQQGSNINDGKSNHAKVDITDLIRESNEKYGSIRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKMSLQELDELYVIFKKELFISCYWYLSCPGLKHHDPSLSYLEQYQIDCQQFRVLFHLLCPWAHSANRDSLALWTFRLLDENSDCLINFKEFSSAIDIMYNGSFTEKLKLLFKLHIPPAYTEVISKTSSKGDELSTEELLYFSQLQVSKPADGKETELGRKSPEKGKGKIDIQAYLSQWQDELLKKEENIKDLPRMNQSQFIQFSKTLYNLFHEDPEEEALYQAIAIVTNLLLRMEEVGRKLHSPASSAKGLSSVACDSGPSEGNTESSVKKDPSSPREEHQWSFAFEQILASLLNEPALVRFFERPLDLKAKLEKAKSSQLRSRTKM", "length": 1122 }, "evidence": [ { "id": "F1NGZ2", "url": "https://omabrowser.org/oma/group/F1NGZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A3KGB4-1", "protein_name": "TBC1 domain family member 8B", "gene_name": "Tbc1d8b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLKPEEVLLKNALKLWLMERSNEYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKQSFAKEDDPEKFREALLKFEKSFGLPEQEKLVTYYSCSYWRGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDAISKLEKTSTVILTESIHVCSQGENHYFSMFLHINETYLLMEQLANYAIKRLFDKETFDNDPVLDDPLQITKRGLEYRAHSEQFKAFFRLPKEETLKEVHECFLWVPFSHFSSHGKMCISENYICFASQDGNLCSVIIPLREVLAIDKTDDSNRSVIISIKGKTAFRFSELKDFEQLVAKLRLKCRAASTQDDVSTEVAVSSDSTGPSENFEEQPLTCPKECSKTVNTEALMTVFHPQNLENLDSKMLKEKMKEQSWNILFSECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPGYYAEVVEQSLGTSNLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRDHLPQLTDHMTDMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVINKDSPLPSNVQQGSNISNEKSDHTKVDITDLIKESNEKYGSIRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKMSLQELDELYVIFKKELFISCYWYLSCPGLKHHDPSLPYLEQYQIDCQQFRVLYHLLSPWAHSANRDSLALWTFRLLDENSDCLINFKEFSSAIDIMYNGSFTDKLKLLFKLHIPPAYTEVMSKTSSKGDELSTEELLYFSQLQVSKPADEKETESGRNSPEKGKGKIDIQAYLSQWQDELLKKEETIKDLPRMNQSQFIQFSKTLYNLFHEDPEEESLYQAIAIVTNLLLRMEEVGRKLHSPASSASTARDSGPSEGNAESSVKKDLPSPREEHQWSFAFEQILASLLNEPALVRFFERPLDLKAKLENAKSSQLRSRTKM", "length": 1114 }, "evidence": [ { "id": "F1NGZ2", "url": "https://omabrowser.org/oma/group/F1NGZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0R0W9-1", "protein_name": "TBC1 domain family member 8B", "gene_name": "tbc1d8b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWLKPEEVLLKNALKLWVTEKSNDYFVLQRRRGYGEDSGGLTGLLVGTLDTVLDSTAKVAPFRILHQTPDSQVYWTIACGASLEEISQHWDWLQQNIVRTLSVFDSGEDITSFVQGKIRGLIAEEGTSAGDEEDPERFREAVLRFERLFGLPQREKLVTYFSCSYWRGRVPNQGWIYLSTNFLCFYSYMLGNEVKLVYPWDEVSRLERTSSVLLAESIRVRVRGEDHFFSMLLRLQQTYLIMQQLADYAIVRFFDKETFHAEHPLANPLHITQRALEIHARNQSFRSFFRLPQEENLCEVYESFLWVPFSHVNTLGKICVSENYLCFASQDGSQCHLIIPLWEVFSVELPDRSSRALTVCLRGKRALRFSEVRDFERLAATIRRKCGTLGSPQHCITNPDEEGVMVGQSQAVSTEALMNVFHPHDAENLDPKMLKERMKEQSWQIHFAEYGRGTGMFCTKKTRDLIVRGVPETLRGELWMLFSGAVHDMISHPGYYGRLLEDCMGSSSLACDEIERDLHRSLPEHPAFQSDTGISALRRVLTAYAHRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIREHLTQLTEHMTDLSFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAVLDYNMDNLLCCNDDAEAVTVLNRFFDSVTNKDSPLPATVQQASATANDKSIQKVDISDLIKEAYEKYGDIRTEEVENMRKRNKLYVIQTLEDTTKQNVLRVVAQDVKFSASQLDELYLLFKNHDPSLPYLDQYQLDQSQFSSLFNLLQPWTTHTHSRSLARSAFHLLDENGDGLVNFKEFICGLDILYNRSFTEKLKLLFKLHLQPDSAEDGVIRKCPERGRAKVDLQEYLKQWQEDLQRREENIKDLPRINQVQFISLTKTLYSVFHGDEEEESLYRAVARVTSLLLRMEEVGRKLQDSSPQKTPQTTPTSTSQPESSPTKPTSPESETPAESRSTHDQPESPVSQHETAPSHSDITPNSTSHPSTPTSSPTETSSPVLDTPTDTPSSPCTVRDGDWSFSFEQILASLLNEPSVVRFFERVVNTDTLITRARKNQLKDAH", "length": 1108 }, "evidence": [ { "id": "F1NGZ2", "url": "https://omabrowser.org/oma/group/F1NGZ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MSJ6-1", "protein_name": "TBC1 domain family member 8B", "gene_name": "TBC1D8B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLKPEEVLLKNALKLWMMERSNDYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGADREEITKHWEWLEENIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKHSFAKEDDPEKFREALLKFEKCFGLPEQEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDAVSKLEKTSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQLANYAIKRIFDKETFDNDPVLDDPLQITKRGLENRAHSEQFSAFFRLPKEETLKEVHECFLWVPFSHFNTHGKMCISENYICFASQDGNLCSVIIPLREVLAIDKTNDSSKSVVISVKGKTAFRFSEVKEFEELVARLRLKCGATSTQYHDISTEVPVSSDSIDPSDDTEVQSLTCQRECSRTVNTEALMTVFHPQNLETLDSKMLKEKMKEQSWNILFSECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMAANPGYYAEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAFRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRDHLPQLTEHMTDMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLACKDDAEAVTALNRFFNNVTNKDSPLPSSVQQGSNVSDEKSSQIRVDITDLIRESNEKYGNIRYENIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKLSLHELDELYVIFKKELFFSYYWCLSSPVLKHHDPSLPYLEQYQIDCQQFRVLYHLLSPWAHSANRDSLALWTFRLLDENSDCLINFKEFSSAIDIMYNGSFTEKLKLLFKLHISPAYTEVQYKDPSKGDELSKEELLYFSQLHVSKPAKEKEAKSARNSPEKEKEKVNIQAYLSQWQDELLKKEENIKDLPRMNQSQFIQFSKTLYNLFHGDPEEESLYQAIAVVTSLLLRMEEVGRKLHSPTSAMKGLSGAAVCVSGVPSEGQAEKPLEKEPSSPREEPQWSFAFEQILASLLNEPALVKFFEKSIDLKAKLENAKTSQLSCRTKK", "length": 1121 }, "evidence": [ { "id": "F1NGZ2", "url": "https://omabrowser.org/oma/group/F1NGZ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0IIM8-1", "protein_name": "TBC1 domain family member 8B", "gene_name": "TBC1D8B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLKPEEVLLKNALKLWLMERSNDYFVLQRRRGYGEEGGGGLTGLLVGTLDSVLDSTAKVAPFRILHQTPDSQVYLSIACGANREEITKHWDWLEQNIMKTLSVFDSNEDITNFVQGKIRGLIAEEGKHCFAKEDDPEKFREALLKFEKCFGLPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEVSKLEKTSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQLANYAIRRLFDKETFDNDPVLYNPLQITKRGLENRAHSEQFNAFFRLPKGESLKEVHECFLWVPFSHFNTHGKMCISENYICFASQDGNQCSVIIPLREVLAIDKTNDSSKSVIISIKGKTAFRFHEVKDFEQLVAKLRLRCGAASTQYHDISTELAISSESTEPSDNFEVQSLTSQRECSKTVNTEALMTVFHPQNLETLNSKMLKEKMKEQSWKILFAECGRGVSMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQSDTGISALRRVLTAYAYRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIRDHLPQLTEHMTDMTFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNLDKLLTCKDDAEAVTALNRFFDNVTNKDSPLPSNVQQGSNVSDEKTSHTRVDITDLIRESNEKYGNIRYEDIHSMRCRNRLYVIQTLEETTKQNVLRVVSQDVKLSLQELDELYVIFKKELFLSCYWCLGCPVLKHHDPSLPYLEQYQIDCQQFRALYHLLSPWAHSANKDSLALWTFRLLDENSDCLINFKEFSSAIDIMYNGSFTEKLKLLFKLHIPPAYTEVKSKDASKGDELSKEELLYFSQLHVSKPANEKEAESAKHSPEKGKGKIDIQAYLSQWQDELFKKEENIKDLPRMNQSQFIQFSKTLYNLFHEDPEEESLYQAIAVVTSLLLRMEEVGRKLHSPTSSAKGFSGTVCGSGGPSEEKTGSHLEKDPCSFREEPQWSFAFEQILASLLNEPALVRFFEKPIDVKAKLENARISQLRSRTKM", "length": 1120 }, "evidence": [ { "id": "F1NGZ2", "url": "https://omabrowser.org/oma/group/F1NGZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glomerular filtration", "id": "GO:0003094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003094", "evidence": [ { "database": "UniProtKB", "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "F1NGZ2", "url": "https://www.uniprot.org/uniprotkb/F1NGZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 893, "end_pos": 895, "annotation": "n_glycosylation_sequon" }, { "start_pos": 989, "end_pos": 991, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGZ2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 1126, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGZ2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGZ2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 238, "end_pos": 240 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 730, "end_pos": 732 }, { "start_pos": 893, "end_pos": 895 }, { "start_pos": 989, "end_pos": 991 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NVY8-1", "uniprot_ac": "F1NVY8", "uniprot_id": "F1NVY8_CHICK", "mass": { "chemical_mass": 84976.0, "monoisotopic_mass": 84976.0 }, "refseq": { "ac": "XP_004936083", "name": "E3 ubiquitin-protein ligase LNX isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936083" }, "gene_names": [ { "name": "LNX1", "type": "recommended", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "name": "LNX1", "type": "synonym", "evidence": [ { "id": "XP_004936083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936083" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase LNX", "type": "recommended", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase LNX isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004936083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936083" } ] }, { "name": "Numb-binding protein 1", "type": "synonym", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase LNX", "type": "synonym", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936083" } ] }, { "annotation": "E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8#function" }, { "database": "UniProtKB", "id": "ARBA00055799", "url": "https://www.uniprot.org/uniprotkb/ARBA00055799#function" }, { "database": "UniProtKB", "id": "A0A8V0YGT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT2#function" }, { "database": "UniProtKB", "id": "A0A8V0YN60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN60#function" } ] }, { "annotation": "Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8#function" }, { "database": "UniProtKB", "id": "ARBA00056865", "url": "https://www.uniprot.org/uniprotkb/ARBA00056865#function" }, { "database": "UniProtKB", "id": "A0A8V0YGT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT2#function" }, { "database": "UniProtKB", "id": "A0A8V0YN60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN60#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LNX1", "url": "https://www.uniprot.org/uniprotkb/F1NVY8", "locus": { "chromosome": "4", "start_pos": 65238442, "end_pos": 65169604, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014199", "url": "https://www.ensembl.org/id/ENSGALG00010014199" } ] } } ], "crossref": [ { "id": "F1NVY8", "url": "https://alphafold.ebi.ac.uk/entry/F1NVY8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013940", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013940", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06678", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06678", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06680", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06680", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16780", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16780", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422752", "url": "https://www.ncbi.nlm.nih.gov/gene/422752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422752", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NHNMAPA", "url": "https://omabrowser.org/oma/group/NHNMAPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGT2", "url": "https://www.orthodb.org/?gene=A0A8V0YGT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN60", "url": "https://www.orthodb.org/?gene=A0A8V0YN60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YV11", "url": "https://www.orthodb.org/?gene=A0A8V0YV11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NVY8", "url": "https://www.orthodb.org/?gene=F1NVY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004936083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YV11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NVY8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEENSPALCVTCGQAHLPEENHLYSYTEEVDDDLICHICLQPLLQPLDTLCGHTFCTACLTNFLLEKDFCPMDRKLVALQNCRKSSILVNNLLDKLMVSCPFTEHCSEVVQRGHLEQHFQTRCKGASHYGLTKERKRRSQDCSPDRSSSLAVAALGPELSAAAAIALMTDEPGLVNPAFSPTSEDSQSGSGPRDLHCSNRNRTRHFERSTIRSRSFKKINKAFSVLRRTKSGSAVSNQVDQEREAVGNSAAGEEDSECSIPIPATKTQHSVERPARVTKNKTENLLLSRFSSASIFKDWKYKMVKKGFPRLYHLIPDGEITCIKINRTDPHENLAIRIVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDMILKVNGMDIKNVPHHYALSILKQPCHVLRLTVLREQRYRCRSSGLSLDAHCSRDDSFHVVLNKSSPDEQLGIKLVRRADEPGVFIFNLLDGGVAARDGQLQENDRVLAINGHDHRYGSPESAAQLIQASERHVHFVVSRQTRQQPPDILQETGWSYSSSPQPCPAERINASKSTLHTVTCHEKVVAVRKDHTESLGMTVAGGATNREWDLPIYVISVEPGGVISRDSRIKTGDILLNVNGIDLTGVSRNEAVALLKNTSSSVVLKALEMRTCDGRERSEAAEHSEWSPSWVTWLGLPRYLYSCKEIVLRRNTSGSLGFSIVGGYEEHTGNKPFFIKSIVGGTPAYNDGRIRCGDILLAVNGRNTSGMMHACLARMLKELKGKITLTIVSWPGTFL", "length": 766, "header": "tr|F1NVY8-1|F1NVY8_CHICK Isoform 1 of E3 ubiquitin-protein ligase LNX OS=Gallus gallus OX=9031 GN=LNX1 PE=4 SV=4 CANONICAL=F1NVY8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGT2-1", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#A0A8V0YGT2-1", "sequence": { "sequence": "MKALLLLVLPWLSPANYIDNVGNLHLLYSELCKGASHYGLTKERKRRSQDCSPDRSSSLAVAALGPELSAAAAIALMTDEPGLVNPAFSPTSEDSQSGSGPRDLHCSNRNRTRHFERSTIRSRSFKKINKAFSVLRRTKSGSAVSNQVDQEREAVGNSAAGEEGFPRLYHLIPDGEITCIKINRTDPHENLAIRIVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDMILKVNGMDIKNVPHHYALSILKQPCHVLRLTVLREQRYRCRSSGLSLDAHCSRDDSFHVVLNKSSPDEQLGIKLVRRADEPGVFIFNLLDGGVAARDGQLQENDRVLAINGHDHRYGSPESAAQLIQASERHVHFVVSRQTRQQPPDILQETGWSYSSSPQPCPAERINASKSTLHTVTCHEKVVAVRKDHTESLGMTVAGGATNREWDLPIYVISVEPGGVISRDSRIKTGDILLNVNGIDLTGVSRNEAVALLKNTSSSVVLKALEMRTCDGRERSEAAEHSEWSPSWVTWLGLPRLLCFRYLYSCKEIVLRRNTSGSLGFSIVGGYEEHTGNKPFFIKSIVGGTPAYNDGRIRCGDILLAVNGRNTSGMMHACLARMLKELKGKITLTIVSWPGTFL", "length": 628, "header": "tr|A0A8V0YGT2-1|F1NVY8_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase LNX OS=Gallus gallus OX=9031 GN=LNX1 PE=4 SV=1 CANONICAL=F1NVY8-1" }, "locus": { "chromosome": "4", "start_pos": 65237081, "end_pos": 65179956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034184.1", "url": "https://www.ensembl.org/id/ENSGALT00010034184.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020080.1", "url": "https://www.ensembl.org/id/ENSGALP00010020080.1" } ] } }, { "isoform_ac": "A0A8V0YN60-1", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#A0A8V0YN60-1", "sequence": { "sequence": "MKALLLLVLPWLSPANYIDNVGNLHLLYSELCKGASHYGLTKERKRRSQDCSPDRSSSLAVAALGPELSAAAAIALMTDEPGLVNPAFSPTSEDSQSGSGPRDLHCSNRNRTRHFERSTIRSRSFKKINKAFSVLRRTKSGSAVSNQVDQEREAVGNSAAGEEDSECSIPIPATKTQHSVERPARVTKNKTENLLLSRFSSASIFKDWKYKMVKKGFPRLYHLIPDGEITCIKINRTDPHENLAIRIVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDMILKVNGMDIKNVPHHYALSILKQPCHVLRLTVLREQRYRCRSSGLSLDAHCSRDDSFHVVLNKSSPDEQLGIKLVRRADEPGVFIFNLLDGGVAARDGQLQENDRVLAINGHDHRYGSPESAAQLIQASERHVHFVVSRQTRQQPPDILQETGWSYSSSPQPCPAERINASKSTLHTVTCHEKVVAVRKDHTESLGMTVAGGATNREWDLPIYVISVEPGGVISRDSRIKTGDILLNVNGIDLTGVSRNEAVALLKNTSSSVVLKALEMRTCDGRERSEAAEHSEWSPSWVTWLGLPRYLYSCKEIVLRRNTSGSLGFSIVGGYEEHTGNKPFFIKSIVGGTPAYNDGRIRCGDILLAVNGRNTSGMMHACLARMLKELKGKITLTIVSWPGTFL", "length": 675, "header": "tr|A0A8V0YN60-1|F1NVY8_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase LNX OS=Gallus gallus OX=9031 GN=LNX1 PE=4 SV=1 CANONICAL=F1NVY8-1" }, "locus": { "chromosome": "4", "start_pos": 65237081, "end_pos": 65179956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034177.1", "url": "https://www.ensembl.org/id/ENSGALT00010034177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020077.1", "url": "https://www.ensembl.org/id/ENSGALP00010020077.1" } ] } }, { "isoform_ac": "A0A8V0YV11-1", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#A0A8V0YV11-1", "sequence": { "sequence": "MEENSPALCVTCGQAHLPEENHLYSYTEEVDDDLICHICLQPLLQPLDTLCGHTFCTACLTNFLLEKDFCPMDRKLVALQNCRKSSILVNNLLDKLMVSCPFTEHCSEVVQRGHLEQHFQTRCKGASHYGLTKERKRRSQDCSPDRSSSLAVAALGPELSAAAAIALMTDEPGLVNPAFSPTSEDSQSGSGPRDLHCSNRNRTRHFERSTIRSRSFKKINKAFSVLRRTKSGSAVSNQVDQEREAVGNSAAGEEDSECSIPIPATKTQHSVERPARVTKNKTENLLLSRFSSASIFKDWKYKMVKKGFPRLYHLIPDGEITCIKINRTDPHENLAIRIVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDMILKVNGMDIKNVPHHYALSILKQPCHVLRLTVLREQRYRCRSSGLSLDAHCSRDDSFHVVLNKSSPDEQLGIKLVRRADEPGVFIFNLLDGGVAARDGQLQENDRVLAINGHDHRYGSPESAAQLIQSTLHTVTCHEKVVAVRKDHTESLGMTVAGGATNREWDLPIYVISVEPGGVISRDSRIKTGDILLNVNGIDLTGVSRNEAVALLKNTSSSVVLKALEMRTCDGRERSEAAEHSEWSPSWVTWLGLPRYLYSCKEIVLRRNTSGSLGFSIVGGYEEHTGNKPFFIKSIVGGTPAYNDGRIRCGDILLAVNGRNTSGMMHACLARMLKELKGKITLTIVSWPGTFL", "length": 721, "header": "tr|A0A8V0YV11-1|F1NVY8_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase LNX OS=Gallus gallus OX=9031 GN=LNX1 PE=4 SV=1 CANONICAL=F1NVY8-1" }, "locus": { "chromosome": "4", "start_pos": 65237081, "end_pos": 65176062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034210.1", "url": "https://www.ensembl.org/id/ENSGALT00010034210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020096.1", "url": "https://www.ensembl.org/id/ENSGALP00010020096.1" } ] } }, { "isoform_ac": "F1NVY8-1", "url": "https://www.uniprot.org/uniprotkb/F1NVY8/entry#F1NVY8-1", "sequence": { "sequence": "MEENSPALCVTCGQAHLPEENHLYSYTEEVDDDLICHICLQPLLQPLDTLCGHTFCTACLTNFLLEKDFCPMDRKLVALQNCRKSSILVNNLLDKLMVSCPFTEHCSEVVQRGHLEQHFQTRCKGASHYGLTKERKRRSQDCSPDRSSSLAVAALGPELSAAAAIALMTDEPGLVNPAFSPTSEDSQSGSGPRDLHCSNRNRTRHFERSTIRSRSFKKINKAFSVLRRTKSGSAVSNQVDQEREAVGNSAAGEEDSECSIPIPATKTQHSVERPARVTKNKTENLLLSRFSSASIFKDWKYKMVKKGFPRLYHLIPDGEITCIKINRTDPHENLAIRIVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDMILKVNGMDIKNVPHHYALSILKQPCHVLRLTVLREQRYRCRSSGLSLDAHCSRDDSFHVVLNKSSPDEQLGIKLVRRADEPGVFIFNLLDGGVAARDGQLQENDRVLAINGHDHRYGSPESAAQLIQASERHVHFVVSRQTRQQPPDILQETGWSYSSSPQPCPAERINASKSTLHTVTCHEKVVAVRKDHTESLGMTVAGGATNREWDLPIYVISVEPGGVISRDSRIKTGDILLNVNGIDLTGVSRNEAVALLKNTSSSVVLKALEMRTCDGRERSEAAEHSEWSPSWVTWLGLPRYLYSCKEIVLRRNTSGSLGFSIVGGYEEHTGNKPFFIKSIVGGTPAYNDGRIRCGDILLAVNGRNTSGMMHACLARMLKELKGKITLTIVSWPGTFL", "length": 766, "header": "tr|F1NVY8-1|F1NVY8_CHICK Isoform 1 of E3 ubiquitin-protein ligase LNX OS=Gallus gallus OX=9031 GN=LNX1 PE=4 SV=4 CANONICAL=F1NVY8-1" }, "locus": { "chromosome": "4", "start_pos": 65237081, "end_pos": 65176062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010034196.1", "url": "https://www.ensembl.org/id/ENSGALT00010034196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020089.1", "url": "https://www.ensembl.org/id/ENSGALP00010020089.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 713, "start_aa": "Thr", "end_pos": 713, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr713", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422752", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BIK0-1", "protein_name": "E3 ubiquitin-protein ligase LNX", "gene_name": "LNX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLSDPADEPDLSPAPLCVVCGQAHSPEENHFYTYPEEVDDDLICHICLQALLDPLDTPCGHTYCTVCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCEEVLQRCDLEHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLTATALSPEASAAATISLMTDEPGLDNPAYVSTAEDGQPATGPLDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSTVANQSDQGREDSENTTAPDIFPRLYHLIPDGEITSIKINRVDPNENLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVRHSYALRLLRQPCHVLRLTVLREQKFRSRNDTPPLDTYGPRDDSFHVILNKSSPDEQLGIKLVRRVDEPGVFIFNVLDGGVADRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQAQQQGPDIFQEASWSSNGSQSPGPGDRSNTPKPLHPGVTCHEKVVSVRKEPSESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRSEAVALLKSTSSSVVLKALEVKEYEPQEDCSNPAALDSNHNNTAPPGDWSPSWVMWLELPQYLYNCKDVVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGKITLTIVSWPGTFL", "length": 733 }, "evidence": [ { "id": "F1NVY8", "url": "https://omabrowser.org/oma/group/F1NVY8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B6RHI6-1", "protein_name": "E3 ubiquitin-protein ligase LNX", "gene_name": "Lnx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNQPDLADDPDPSPEPLCVVCGQNHSPEENHFYTYTEDVDDDLVCHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSNILVNKLLNKLLVNCPFTEHCSEVLQRCNLQYHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLTATTLSPEVSAAATISLMTDEPGLDNPAYTSSVEDGEPVTNPSDTGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSAVANHADQGRDNSENDTVPEVFPRLFHLIPDGEITSIKINRVDPNESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAPAPDSYGPRDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQPSPDIFQEAGCISNGQQSPVSGERSTSSKPAATCHEKVVSVQKDPNESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSTPSSVVLKALEVKEQETQEDCSPAALDSNHNVTPPGDWSPSWVMWLELPQYLYNCKDVILRRNTAGSLGFCIVGGYEEYSGNQPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMMHACLARMLKELKGKITLTIASWPGTFL", "length": 728 }, "evidence": [ { "id": "F1NVY8", "url": "https://omabrowser.org/oma/group/F1NVY8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O70263-1", "protein_name": "E3 ubiquitin-protein ligase LNX", "gene_name": "Lnx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNQPDLADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGPRDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASKPAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKEQEAQEDCSPAALDSNHNVTPPGDWSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL", "length": 728 }, "evidence": [ { "id": "F1NVY8", "url": "https://omabrowser.org/oma/group/F1NVY8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBB1-1", "protein_name": "E3 ubiquitin-protein ligase LNX", "gene_name": "LNX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNQPESANDPEPLCAVCGQAHSLEENHFYSYPEEVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPMDRKPLVLQHCKKSSILVNKLLNKLLVTCPFREHCTQVLQRCDLEHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLTATAPSPEVSAAATISLMTDEPGLDNPAYVSSAEDGQPAISPVDSGRSNRTRARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFPRLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLWLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSPSWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIVSWPGTFL", "length": 728 }, "evidence": [ { "id": "F1NVY8", "url": "https://omabrowser.org/oma/group/F1NVY8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "synapse maturation", "id": "GO:0060074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060074", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "PDZ domain binding", "id": "GO:0030165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030165", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "F1NVY8", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine 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"A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor 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"ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating 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"evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor 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"ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NVY8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 766, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NVY8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NVY8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 713 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 540, "end_pos": 542 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 682, "end_pos": 684 }, { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NAJ2-1", "uniprot_ac": "F1NAJ2", "uniprot_id": "F1NAJ2_CHICK", "mass": { "chemical_mass": 71000.0, "monoisotopic_mass": 71000.0 }, "refseq": { "ac": "XP_046792374", "name": "peptidylprolyl isomerase domain and WD repeat-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792374" }, "gene_names": [ { "name": "PPWD1", "type": "recommended", "evidence": [ { "id": "F1NAJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ] }, { "name": "PPWD1", "type": "synonym", "evidence": [ { "id": "XP_046792374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792374" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "F1NAJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "F1NAJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2/entry#names_and_taxonomy" } ] }, { "name": "peptidylprolyl isomerase domain and WD repeat-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_046792374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792374" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_059536) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046792374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792374" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NAJ2", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPWD1", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2", "locus": { "chromosome": "Z", "start_pos": 21137542, "end_pos": 21121724, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012210", "url": "https://www.ensembl.org/id/ENSGALG00010012210" } ] } } ], "crossref": [ { "id": "F1NAJ2", "url": "https://alphafold.ebi.ac.uk/entry/F1NAJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014756", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014756", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01927", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01927", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427163", "url": "https://www.ncbi.nlm.nih.gov/gene/427163", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427163", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427163", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMVEYWR", "url": "https://omabrowser.org/oma/group/GMVEYWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGU2", "url": "https://www.orthodb.org/?gene=A0A8V0YGU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NAJ2", "url": "https://www.orthodb.org/?gene=F1NAJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45625:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45625:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046792374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046792374", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAJ2", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAJ2-1", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSEPERKRRASGAAENEEEDEEDGERWVGPLPGEAAQTKKRRVLEFEHVYLENLPCASMYERSYMHRDVITHVACTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYSPGQCEWVYCPGDAISSVATSEKTTGKIFIYDGRGNNQPLHVFDKLHTSSLTQIRLNPVYKVVVSSDKSGMIEYWTGTPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPSSISFSPDGKKMATLGSDRKVRIFRFLTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIIFDETGHFVLYGTMLGIKVINVETNRCIRILGKQENIRVMQLALFQGVAKKHRAAITIEMKASENPVLQNIQADPTVICTAFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHIFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGPNTNGSQFFITVVPTPWLDNKHSVFGRVTKGMEVVQRISNVKVNPKTDKPYEDISIINITVK", "length": 625, "header": "tr|F1NAJ2-1|F1NAJ2_CHICK Isoform 1 of peptidylprolyl isomerase OS=Gallus gallus OX=9031 GN=PPWD1 PE=1 SV=2 CANONICAL=F1NAJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YGU2-1", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2/entry#A0A8V0YGU2-1", "sequence": { "sequence": "MASSEPERKRRASGAAENEEEDEEDGERWVGPLPGEAAQTKKRRVLEFEHVYLENLPCASMYERSYMHRDVITHVACTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYSPGQCEWVYCPGDAISSVATSEKTTGKIFIYDGRGNNQPLHVFDKLHTSSLTQIRLNPVYKVVVSSDKSGMIEYWTGTPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPSSISFSPDGKKMATLGSDRKVRIFRFLTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIIFDETGHFVLYGTMLGIKVINVETNRCIRILGKQENIRVMQLALFQGVAKKHRAAITIEMKASENPVLQNIQADPTVICTAFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHIFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGPNTNGSQFFITVVPTYPQTALARQQTQRVWTSD", "length": 596, "header": "tr|A0A8V0YGU2-1|F1NAJ2_CHICK Computationally mapped isoform of peptidylprolyl isomerase OS=Gallus gallus OX=9031 GN=PPWD1 PE=1 SV=1 CANONICAL=F1NAJ2-1" }, "locus": { "chromosome": "Z", "start_pos": 21135667, "end_pos": 21121740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029268.1", "url": "https://www.ensembl.org/id/ENSGALT00010029268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016986.1", "url": "https://www.ensembl.org/id/ENSGALP00010016986.1" } ] } }, { "isoform_ac": "F1NAJ2-1", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2/entry#F1NAJ2-1", "sequence": { "sequence": "MASSEPERKRRASGAAENEEEDEEDGERWVGPLPGEAAQTKKRRVLEFEHVYLENLPCASMYERSYMHRDVITHVACTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYSPGQCEWVYCPGDAISSVATSEKTTGKIFIYDGRGNNQPLHVFDKLHTSSLTQIRLNPVYKVVVSSDKSGMIEYWTGTPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPSSISFSPDGKKMATLGSDRKVRIFRFLTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIIFDETGHFVLYGTMLGIKVINVETNRCIRILGKQENIRVMQLALFQGVAKKHRAAITIEMKASENPVLQNIQADPTVICTAFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHIFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGPNTNGSQFFITVVPTPWLDNKHSVFGRVTKGMEVVQRISNVKVNPKTDKPYEDISIINITVK", "length": 625, "header": "tr|F1NAJ2-1|F1NAJ2_CHICK Isoform 1 of peptidylprolyl isomerase OS=Gallus gallus OX=9031 GN=PPWD1 PE=1 SV=2 CANONICAL=F1NAJ2-1" }, "locus": { "chromosome": "Z", "start_pos": 21135767, "end_pos": 21121740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029278.1", "url": "https://www.ensembl.org/id/ENSGALT00010029278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016994.1", "url": "https://www.ensembl.org/id/ENSGALP00010016994.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 578, "start_aa": "Thr", "end_pos": 578, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr578", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:427163", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427163", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZVP6-1", "protein_name": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "gene_name": "Ppwd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEIGSDSQLKRRRRRDPEGSEKTELSEREPALAVEGREENDDENEERWVGPLPVEATLAKKRKVLEFERVYLENLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHVSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKTVNWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAAATIEMKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIVHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK", "length": 646 }, "evidence": [ { "id": "F1NAJ2", "url": "https://omabrowser.org/oma/group/F1NAJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SKT8-1", "protein_name": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "gene_name": "PPWD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAESGSDSQLSKRRRRVPEEPEKTELSERELAVAVAVTQENEEESEERWVGPLPVEATLAKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGIIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPIYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTVVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNERPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK", "length": 646 }, "evidence": [ { "id": "F1NAJ2", "url": "https://omabrowser.org/oma/group/F1NAJ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q29RZ2-1", "protein_name": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "gene_name": "PPWD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAECGSDSQPRRRRRRDPEEPGKTELSAREPVVAVPQENEEENEERWVGPLPVEATLAKKRKVLEFEKVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPYEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSICFSPDGKKLATIGSDRKVRIFRFLTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK", "length": 644 }, "evidence": [ { "id": "F1NAJ2", "url": "https://omabrowser.org/oma/group/F1NAJ2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55F01-1", "protein_name": "peptidylprolyl isomerase", "gene_name": "ppwd1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSENNENEEQLNKKRETSTSNDEDVDKINNKKLKSKTKELPFEQLYLDRLPNSLMYEKSFMHKDICTFIAVSKSDFIVSTDILGYVKFWKKQPIGIEFVKTFKSHVGPVSSLSISFDGQLLCTVGFDKNVRIFDIKNFDLINSFKVPFLPLTCEWVYGVNSSKTLIAISSRESSIINLYDSKSDDTSGKPLHIVELHNKSVHLIKFNQQFQSVISCDIGGSVEYWDIEEPFDQPTNVNFQMKLETDLYDFEKQSTLPISLEISGDGKYLSTMGRDKKIRIFNYKSGKLYRVYDESFAVLQQIQKTEDPIYHLDYADFGRRLAIEKEIDTMYDQFLNNITSKQSPPLNSILFDESNNFLIYSTLVGIKFVNIKTNKVVRVLGKIENSTRFLGLSLYQGKNEGDVTLGTKKRDTENDPTLFCLSFKKQRFYMFTRREPEDNDNPDYGRDVFNEKVTKDEQLLIQNAQRQLPRNAIIHTSLGDIHIMLYPDECPKTVENFTTHSKNNYYNGVIFHRVIKGFMIQTGDPQGTGYGGDSIWKKEFEDEFNRNLRHDRPFTLSMANAGPNTNGSQFFITTVPVTRLDNKHTVFGRVYKGTEVVTAIEKSKTDQDDKPLNDISILNIKITQDVPLEFQNKKI", "length": 635 }, "evidence": [ { "id": "F1NAJ2", "url": "https://omabrowser.org/oma/group/F1NAJ2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8CEC6-1", "protein_name": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "gene_name": "Ppwd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATESGSDSQLRRRRRRDPEGSEKTELSEREPALAVAGSEENDDENEERWVGPLPVEATLAKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHVSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSICFSPDGKKIATIGSDRKVRIFRFLTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLVNIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAAATIEMKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKTADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIVHTSMGDIHIKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK", "length": 646 }, "evidence": [ { "id": "F1NAJ2", "url": "https://omabrowser.org/oma/group/F1NAJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8W4D0-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase CYP71", "gene_name": "CYP71", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEESKNGGTTIPTEELAVVAVPPVVEEEEPMVGPGPAPRGKRKRPLQFEQAYLDSLPSANMYEKSYMHRDVVTHVAVSAAEFFISGSMDGHLKFWKKKGVGIEFAKHFRSHLGPIEGLAVSIDGLLCCTISNDHAVKIYDVVNYDMMAMIRLPYIPGAVEWVYKQGDVKAKLAVSDRDSLFVHIYDPRSGSNEPIASKEIHMNPIKVMKYNPVSDTMISGDTKGIIEYWSATTLQFPEDEVNFKLKSDTNLFEIIKCKTTISAIEVSPDGKQFSITAPDRRIRVFWFRTGKLRRVYDESLVVAQDLQRSDAPLYRLEAIDFGRRMAVEKELEKTESAPQPNAVFDESSNFLIYATFLGIKVINLHTNTVARILGKVESNERYLRVALYQGDQGGKKVRKIPAAAANVNESKEPLTDPTILCCAFKKHRIYMFSRREPEEPEDASQGRDVFNEKPAADELMSVSDIGNSATTSLPENVIMHTTLGDIHMKLYPEECPKTVENFTTHCRNGYYDNHLFHRVIRGFMIQTGDPLGDGTGGQSIWGREFEDEFHKSLRHDRPFTLSMANAGPNTNGSQFFITTVATPWLDNKHTVFGRVVKGMDVVQGIEKVKTDKNDRPYQDVKILNVTVPKS", "length": 631 }, "evidence": [ { "id": "F1NAJ2", "url": "https://omabrowser.org/oma/group/F1NAJ2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96BP3-1", "protein_name": "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "gene_name": "PPWD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATLAKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK", "length": 646 }, "evidence": [ { "id": "F1NAJ2", "url": "https://omabrowser.org/oma/group/F1NAJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NAJ2", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "F1NAJ2", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1NAJ2", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "F1NAJ2", "url": "https://www.uniprot.org/uniprotkb/F1NAJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ALG1-1", "F1NCD7-1", "A0A1D5NWE1-1", "A0A8V1A0X8-1", "A0A8V0YZ11-1", "A0A8V0X6B3-1", "A0A8V1AE18-1", "P24367-1", "E1C487-1", "A0A8V0X7D8-1", "A0A1D5PW44-1", "Q5ZLV2-1", "E1BXG9-1", "A0A3Q2U9P1-1", "A0A8V0XUB5-1", "A0A8V0XB51-1", "A0A8V0Y6V0-1", "A0A8V0Z0N7-1", "A0A8V0Z1Z7-1", "A0A8V0Z3A2-1", "A0A8V0ZS95-1", "A0A8V0ZU13-1", "A0A8V0ZEN0-1", "A0A8V0ZIR3-1", "A0A8V0ZPE3-1", "A0A8V0ZGR2-1", "A0A8V1A2D9-1", "A0A8V1AED8-1", "A0A8V1AII9-1", "A0A8V0YN09-1", "A0A8V0XMH4-1", "F1NAJ2-1" ], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] }, { "id": "R-GGA-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NCB0-1", "A0A8V0XUB5-1", "E1BSC0-1", "A0A8V0YUC5-1", "A0A1D5PZS0-1", "Q5ZM36-1", "A0A1D5PW44-1", "Q5ZLV2-1", "F1NAJ2-1", "A0A8V0ZS62-1", "A0A8V0ZU13-1", "F1NHI3-1", "A0A8V0Z3A2-1", "A0A8V0XHD1-1", "A0A8V0ZWH7-1", "A0A3S5ZPN3-1" ], "evidence": [ { "id": "R-GGA-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9794542" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWE1", "gene_name": "FKBP6", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A1D5NWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWE1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A1D5NWE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWE1" } ] } ] }, { "uniprot_ac": "A0A1D5PW44", "gene_name": "PPIL1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A1D5PW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW44" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A1D5PW44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PW44" } ] } ] }, { "uniprot_ac": "A0A1D5PZS0", "gene_name": "PRPF19", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5PZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZS0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5PZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZS0" } ] } ] }, { "uniprot_ac": "A0A3Q2U9P1", "gene_name": "FKBP4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A3Q2U9P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9P1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A3Q2U9P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9P1" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X6B3", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0X6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6B3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0X6B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6B3" } ] } ] }, { "uniprot_ac": "A0A8V0X7D8", "gene_name": "PPIC", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7D8" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0X7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7D8" } ] } ] }, { "uniprot_ac": "A0A8V0XB51", "gene_name": "PIN1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB51" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XB51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB51" } ] } ] }, { "uniprot_ac": "A0A8V0XHD1", "gene_name": "AQR", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XHD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XHD1" } ] } ] }, { "uniprot_ac": "A0A8V0XMH4", "gene_name": "", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XMH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMH4" } ] } ] }, { "uniprot_ac": "A0A8V0XUB5", "gene_name": "PPIL4", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0XUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUB5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0XUB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUB5" } ] } ] }, { "uniprot_ac": "A0A8V0Y6V0", "gene_name": "FKBP1B", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0Y6V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6V0" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0Y6V0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6V0" } ] } ] }, { "uniprot_ac": "A0A8V0YN09", "gene_name": "FKBP1A", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V0YN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V0YN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN09" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1N939-1", "uniprot_ac": "F1N939", "uniprot_id": "F1N939_CHICK", "mass": { "chemical_mass": 73132.0, "monoisotopic_mass": 73132.0 }, "refseq": { "ac": "XP_015133059", "name": "ankyrin repeat domain-containing protein 55 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133059" }, "gene_names": [ { "name": "ANKRD55", "type": "recommended", "evidence": [ { "id": "F1N939", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N939" } ] }, { "name": "ANKRD55", "type": "synonym", "evidence": [ { "id": "XP_015133059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133059" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 55", "type": "synonym", "evidence": [ { "id": "F1N939", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N939/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 55 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015133059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133059" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133059" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1N939", "url": "https://www.uniprot.org/uniprotkb/F1N939" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD55", "url": "https://www.uniprot.org/uniprotkb/F1N939", "locus": { "chromosome": "Z", "start_pos": 17626944, "end_pos": 17685353, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012961", "url": "https://www.ensembl.org/id/ENSGALG00010012961" } ] } } ], "crossref": [ { "id": "F1N939", "url": "https://alphafold.ebi.ac.uk/entry/F1N939", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014717", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014717", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100858831", "url": "https://www.ncbi.nlm.nih.gov/gene/100858831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858831", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VFCKAWT", "url": "https://omabrowser.org/oma/group/VFCKAWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YHT2", "url": "https://www.orthodb.org/?gene=A0A8V0YHT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJS8", "url": "https://www.orthodb.org/?gene=A0A8V0YJS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YPM2", "url": "https://www.orthodb.org/?gene=A0A8V0YPM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N939", "url": "https://www.orthodb.org/?gene=F1N939", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015133059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133059", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YHT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YPM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N939", "url": "https://www.uniprot.org/uniprotkb/F1N939", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N939-1", "url": "https://www.uniprot.org/uniprotkb/F1N939-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFSSSSVFDQHKGTLLPVGDAVEDTDLTVVYQAAASGDVNTLTAVIREDPSILECCDAEGCTPLMHAVSGLQVDTVKLLLKMGANINTQDACGRTSLSLATYLGWLEGCVSLLRNGAKQNIPDKNGRLPLHAATAEPDVRLLNVLLQQSSLSEINHQDNEGMTSLHWAAFHNRPQHVQTLLHKGADLTLVDKDLKTALHWAVQSGNRILCSIILDHYQGPSIINYDDENGKTCMHIAAAAGYSDIISELAKVPECNLQALDVDDRTPLHWAAAAGKADCVQILLELGTDSSPRDINENTPLTYAMYCGHTACVKLLSQENSISELVHQFPSQNNKLLKKEGRFSMLNHIFFKKKKQNQKTIQKDKSRDRYATEETSEVDDIITTFDCVMDTSCKDIPDEHVTTTDFKRRTTDTKYLIPEKKPAECHGLLPVRTQSLPPITAGNSFLTAAASTTSSMSFSSSTQHFAHKSPKSRSEHDLLDHRSSCQALLDNSWNTKPNQMLSHKACTRTPSDKAINGLNSDRSHHVLLCPPHLPSLPRSPSGKNFQKISIDQPKIKEPTPVRDSLAPLPNHCAQRFHLPPQGAKKFKSPPFNSLRTGAVVLPPAPSSKSQKRGHSHNRLLYSFLPDLSGEPLKPSHVLPAIPNQTKSNPAEQLEKSLTNLDTEN", "length": 665, "header": "tr|F1N939-1|F1N939_CHICK Isoform 1 of Ankyrin repeat domain 55 OS=Gallus gallus OX=9031 GN=ANKRD55 PE=4 SV=5 CANONICAL=F1N939-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YHT2-1", "url": "https://www.uniprot.org/uniprotkb/F1N939/entry#A0A8V0YHT2-1", "sequence": { "sequence": "MDFSSSSVFDQHKGTLLPVGDAVEDTDLTVVYQAAASGDVNTLTAVIREDPSILECCDAEGCTPLMHAVSGLQVDTVKLLLKMGANINTQDACGRTSLSLATYLGWLEGCVSLLRNGAKQNIPDKNGRLPLHAATAEPDVRLLNVLLQQSSLSEINHQDNEGMTSLHWAAFHNRPQHVQTLLHKGADLTLVDKDLKTALHWAVQMAAEEQSDRMASDMELHMKQRCVIKFPHVEKMAAASSDNSTKDNLCSGWPCTNVTPQNLEHLDQLIHMNQEIMTLELCKELNISFSALKLWW", "length": 296, "header": "tr|A0A8V0YHT2-1|F1N939_CHICK Computationally mapped isoform of Ankyrin repeat domain 55 OS=Gallus gallus OX=9031 GN=ANKRD55 PE=4 SV=1 CANONICAL=F1N939-1" }, "locus": { "chromosome": "Z", "start_pos": 17684994, "end_pos": 17658028, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031101.1", "url": "https://www.ensembl.org/id/ENSGALT00010031101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018095.1", "url": "https://www.ensembl.org/id/ENSGALP00010018095.1" } ] } }, { "isoform_ac": "A0A8V0YJS8-1", "url": "https://www.uniprot.org/uniprotkb/F1N939/entry#A0A8V0YJS8-1", "sequence": { "sequence": "MDFSSSSVFDQHKGTLLPVGDAVEDTDLTVVYQAAASGDVNTLTAVIREDPSILECCDAEGCTPLMHAVSGLQVDTVKLLLKMGANINTQDACGRTSLSLATYLGWLEGCVSLLRNGAKQNIPDKNGRLPLHAATAEPDVRLLNVLLQQSSLSEINHQDNEGMTSLHWAAFHNRPQHVQTLLHKGADLTLVDKDLKTALHWAVQLLSKSEERGGQLQFSSSCQIPAMKPYKSLIPSTFFSIQREKTTWSRSVSISLTQAFLRGNTFSKCSVALFGPGERGTLDSHGFLCFTSLLHGIIILMYPF", "length": 304, "header": "tr|A0A8V0YJS8-1|F1N939_CHICK Computationally mapped isoform of Ankyrin repeat domain 55 OS=Gallus gallus OX=9031 GN=ANKRD55 PE=4 SV=1 CANONICAL=F1N939-1" }, "locus": { "chromosome": "Z", "start_pos": 17684994, "end_pos": 17664193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031096.1", "url": "https://www.ensembl.org/id/ENSGALT00010031096.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018091.1", "url": "https://www.ensembl.org/id/ENSGALP00010018091.1" } ] } }, { "isoform_ac": "A0A8V0YPM2-1", "url": "https://www.uniprot.org/uniprotkb/F1N939/entry#A0A8V0YPM2-1", "sequence": { "sequence": "MDFSSSSVFDQHKGTLLPVGDAVEDTDLTVVYQAAASGDVNTLTAVIREDPSILECCDAEGCTPLMHAVSGLQVDTVKLLLKMGANINTQDACGRTSLSLATYLGWLEGCVSLLRNGAKQNIPDKNGRLPLHAATAEPDVRLLNVLLQQSSLSEINHQDNEGMTSLHWAAFHNRPQHVQTLLHKGADLTLVDKDLKTALHWAVQSGNRILCSIILDHYQGPSIINYDDENGKTCMHIAAAAGYSDIISELAKVPECNLQALDVDDRTPLHWAAAAGKADCVQILLELGTDSSPRDINENTPLTYAMYCGHTACVKLLSQENSISELVHQFPSQNNKLLKKEGRFSMLNHIFFKKKKQNQKTIQKDKSRDRYATEETSEVDDIITTFDCVMDTSCKDIPDEHVTTTDFKRRTTDTKYLIPEKKPAECHGLLPVRTQSLPPITAGNSFLTAAASTTSSMSFSSSTQHFAHKSPKSRSEHDLLDHRSSCQALLDNSWNTKPNQMLSHKACTRTPSDKAINGLNSDRSHHVLLCPPHLPSLPRSPSGKNFQKISIDQPKIKEPTPVRDSLAPLPNHCAQRSDPNLSAAAL", "length": 586, "header": "tr|A0A8V0YPM2-1|F1N939_CHICK Computationally mapped isoform of Ankyrin repeat domain 55 OS=Gallus gallus OX=9031 GN=ANKRD55 PE=4 SV=1 CANONICAL=F1N939-1" }, "locus": { "chromosome": "Z", "start_pos": 17684994, "end_pos": 17627016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031105.1", "url": "https://www.ensembl.org/id/ENSGALT00010031105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018099.1", "url": "https://www.ensembl.org/id/ENSGALP00010018099.1" } ] } }, { "isoform_ac": "F1N939-1", "url": "https://www.uniprot.org/uniprotkb/F1N939/entry#F1N939-1", "sequence": { "sequence": "MDFSSSSVFDQHKGTLLPVGDAVEDTDLTVVYQAAASGDVNTLTAVIREDPSILECCDAEGCTPLMHAVSGLQVDTVKLLLKMGANINTQDACGRTSLSLATYLGWLEGCVSLLRNGAKQNIPDKNGRLPLHAATAEPDVRLLNVLLQQSSLSEINHQDNEGMTSLHWAAFHNRPQHVQTLLHKGADLTLVDKDLKTALHWAVQSGNRILCSIILDHYQGPSIINYDDENGKTCMHIAAAAGYSDIISELAKVPECNLQALDVDDRTPLHWAAAAGKADCVQILLELGTDSSPRDINENTPLTYAMYCGHTACVKLLSQENSISELVHQFPSQNNKLLKKEGRFSMLNHIFFKKKKQNQKTIQKDKSRDRYATEETSEVDDIITTFDCVMDTSCKDIPDEHVTTTDFKRRTTDTKYLIPEKKPAECHGLLPVRTQSLPPITAGNSFLTAAASTTSSMSFSSSTQHFAHKSPKSRSEHDLLDHRSSCQALLDNSWNTKPNQMLSHKACTRTPSDKAINGLNSDRSHHVLLCPPHLPSLPRSPSGKNFQKISIDQPKIKEPTPVRDSLAPLPNHCAQRFHLPPQGAKKFKSPPFNSLRTGAVVLPPAPSSKSQKRGHSHNRLLYSFLPDLSGEPLKPSHVLPAIPNQTKSNPAEQLEKSLTNLDTEN", "length": 665, "header": "tr|F1N939-1|F1N939_CHICK Isoform 1 of Ankyrin repeat domain 55 OS=Gallus gallus OX=9031 GN=ANKRD55 PE=4 SV=5 CANONICAL=F1N939-1" }, "locus": { "chromosome": "Z", "start_pos": 17684994, "end_pos": 17634784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031104.1", "url": "https://www.ensembl.org/id/ENSGALT00010031104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018098.1", "url": "https://www.ensembl.org/id/ENSGALP00010018098.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858831", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PT06-1", "protein_name": "Ankyrin repeat domain-containing protein 55 isoform X1", "gene_name": "ankrd55", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFNSSSVFEQHKEAAEEVDLNVVYQAAANGDVNTLTTVIREDPSILECCDGEGSTPLMHAVSGRQVDTVKLLLKMGASINTQDACGRTSLSLGTYLGWLEGCVCLLRNGAKQNIPDKNGRLPIHAATAETDFRLMAVLLQQSTLCEINHQDNEGMTALHWACFHNRPEHSQALLQKGADPTLVDKDFKTALHWAVQSGSRLMCSLILEHNLGSSVINYDDENGKTCVHIAAAAGFSDIIYELSRISETNLQALDVDERTPLHWAAAAGKDDCVQVLLELGVEPSPRDINENTPLTYAMYCGHTACIKLLSTENRSESSRPLHAQNSDPSIRKEGKFRMLNHIFSKKKKDLHPCQQTDSSQECQLKEETSEVDDIITMFDCVAEPFSRDESENSSTVRKRTNDSEKVHLVEDTSCKDFPILPPIRTQSLPPITLGKSLLVNSLAHRTSGGHVVGHLAHRSQKSKSEHDLFDGKSKEQKAIGHGWKTESSHILTHKAWIATPSERLLDKLLHASSSPLDVLCSNQTPYIQRNDQAAQNHLLPLRVRESALTRNSLAPIRDHCTHRFSLPPDQVSQGVRKSKSSVGVGLAVLPPPFASKLHRVGVPQSPSLGSFPTPLTGEPLRNIQVLPAIPPQRKRSPSPLTTLSHSKITD", "length": 651 }, "evidence": [ { "id": "F1N939", "url": "https://omabrowser.org/oma/group/F1N939/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M1X7-1", "protein_name": "Ankyrin repeat domain 55", "gene_name": "Ankrd55", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMRQATMDFSSSSVFDQHKGDSSEEVDLTMVYQAASNGDVNSLTAVIREDPSILECCDSEGCTPLMHAVSGRQVDTVKLLLKMGANINTQDAYGRTSLCLATYLGWLEGCVSLLRNGAKHNIPDKNGRLPLHAATAEPDVRLLIVLLQQSSLSEINHQDTEGMTPLHWAAFHNRPQHTQMLLKKGADPTLVDKDFKTALHWAVQSGNRILCSIILSHRQGPSIINYDDESGKTCVHIAAASGFGDIIHDLAKVPECNLQALDVDDRTPLHWAAAAGKAECVQSLLDLGMDSNLRDINESTPLAYALYCGHTACVRLLSREGRAEPARPLPSQNSQPQKKEGRFSVLNQIFCKNKKEEQKAHQKEQSRARPKEEDTSEVNDIIATFDSVVDTNCQDQPGDQVDMVVFKKRTSENSKYLLPEKKSLARKGLPPIRTQSLPPITLGSNFLTASHGATSHAGLNSGLQHTAQRSQKSRSEQDLLNNRTGCQVSLDNPWKGDTRQAFSCKAWTVSSSDKLLDRMFTGQPGHQELSGPPHLPHLPNPSPGQGLQHLSPNRPKVRDFPFTRNSLAPLPDQKFLSGEPLRTNRVLPAIPSQRGHDPPAEESEWSSSPTHDEN", "length": 614 }, "evidence": [ { "id": "F1N939", "url": "https://omabrowser.org/oma/group/F1N939/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BLD6-1", "protein_name": "Ankyrin repeat domain-containing protein 55", "gene_name": "Ankrd55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQATMDFSTSSVFDQHKGDSSEEVDLAMVYQAASNGDVNSLTSVIREDPSILECCDSEGCTPLMHAVSGRQVDTVKLLLKMGANINTQDAYGRTSLCLATYLGWLEGCVSLLRNGAKHNIPDKNGRLPLHAATAEPDVRLLIVLLQQSSLSEINHQDTEGMTPLHWAAFHNRPQHTQMLLKKGADPTLVDKDFKTALHWAVQSGNRILCSIILSHRQGPSIINYDDESGKTCVHIAAASGFGDIINDLAKVPECNLQALDVDDRTPLHWAAASGKAECVQSLLDLGMDSNLRDINESTPLAYALYCGHTACVRLLSREGRAEPARPLPSQNSQPQKKEGRFSMLNQIFCKNKKEEQKAHQKDQSRARPKEEETSEVNDIIATFDSVVDTNCQGQPGDQVDMVVFKKRTSENSKYLLPEKKSLARKGLPPIRTQSLPPITLGGHFLTASQGAVSHAGLNAGPQHTAQRSQKSRSEQDLLNNRTGCPVSLENPWKGDTRQVFSCKAWTVSSSDKLLDRLFAGQPGHQELSGPPHLPHLHNPSSGQALQHLSPNRPKIRDLPFTRNSLAPLPDQKFLSGEPLRTNRVLPAIPSQRGHDPSPAGESQRGHDPPRAEESGGSSSPTHDEN", "length": 626 }, "evidence": [ { "id": "F1N939", "url": "https://omabrowser.org/oma/group/F1N939/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1N939-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 665, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N939-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N939" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 644, "end_pos": 646 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C2X1-1", "uniprot_ac": "E1C2X1", "uniprot_id": "E1C2X1_CHICK", "mass": { "chemical_mass": 49402.0, "monoisotopic_mass": 49402.0 }, "refseq": { "ac": "XP_025005791", "name": "protein phosphatase 2, regulatory subunit B, gamma isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005791" }, "gene_names": [ { "name": "PPP2R2C", "type": "recommended", "evidence": [ { "id": "E1C2X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2X1" } ] }, { "name": "PPP2R2C", "type": "synonym", "evidence": [ { "id": "XP_025005791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005791" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "type": "recommended", "evidence": [ { "id": "E1C2X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 2, regulatory subunit B, gamma isoform X6", "type": "synonym", "evidence": [ { "id": "XP_025005791", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005791" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005791" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C2X1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP2R2C", "url": "https://www.uniprot.org/uniprotkb/E1C2X1", "locus": { "chromosome": "4", "start_pos": 79055956, "end_pos": 79231953, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011465", "url": "https://www.ensembl.org/id/ENSGALG00010011465" } ] } } ], "crossref": [ { "id": "E1C2X1", "url": "https://alphafold.ebi.ac.uk/entry/E1C2X1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015531", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015531", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422858", "url": "https://www.ncbi.nlm.nih.gov/gene/422858", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422858", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422858", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LVPMELI", "url": "https://omabrowser.org/oma/group/LVPMELI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NZN8", "url": "https://www.orthodb.org/?gene=A0A1D5NZN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PB76", "url": "https://www.orthodb.org/?gene=A0A1D5PB76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4Y1", "url": "https://www.orthodb.org/?gene=A0A8V0Y4Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y4Z0", "url": "https://www.orthodb.org/?gene=A0A8V0Y4Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y9P3", "url": "https://www.orthodb.org/?gene=A0A8V0Y9P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB72", "url": "https://www.orthodb.org/?gene=A0A8V0YB72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI33", "url": "https://www.orthodb.org/?gene=A0A8V0YI33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YI41", "url": "https://www.orthodb.org/?gene=A0A8V0YI41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C2X1", "url": "https://www.orthodb.org/?gene=E1C2X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025005791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005791", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NZN8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PB76", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PB76-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y4Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y9P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YI41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YI41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2X1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2X1-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIDQADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 428, "header": "tr|E1C2X1-1|E1C2X1_CHICK Isoform 1 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=2 CANONICAL=E1C2X1-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZN8-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A1D5NZN8-1", "sequence": { "sequence": "MGEDTDTRKINHSFLRDHNYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 447, "header": "tr|A0A1D5NZN8-1|A0A1D5NZN8_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79182085, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027444.1", "url": "https://www.ensembl.org/id/ENSGALT00010027444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015698.1", "url": "https://www.ensembl.org/id/ENSGALP00010015698.1" } ] } }, { "isoform_ac": "A0A1D5PB76-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A1D5PB76-1", "sequence": { "sequence": "MSQKQVGAPPGESAVDWCLYQLNGAAEFEVSEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 456, "header": "tr|A0A1D5PB76-1|E1C2X1_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79231720, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027448.1", "url": "https://www.ensembl.org/id/ENSGALT00010027448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015702.1", "url": "https://www.ensembl.org/id/ENSGALP00010015702.1" } ] } }, { "isoform_ac": "A0A8V0Y4Y1-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A8V0Y4Y1-1", "sequence": { "sequence": "MPDCAVILLDFTSQADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 438, "header": "tr|A0A8V0Y4Y1-1|E1C2X1_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79115178, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027436.1", "url": "https://www.ensembl.org/id/ENSGALT00010027436.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015690.1", "url": "https://www.ensembl.org/id/ENSGALP00010015690.1" } ] } }, { "isoform_ac": "A0A8V0Y4Z0-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A8V0Y4Z0-1", "sequence": { "sequence": "MERPSSRSPKSKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 401, "header": "tr|A0A8V0Y4Z0-1|A0A8V0Y4Z0_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79231466, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027446.1", "url": "https://www.ensembl.org/id/ENSGALT00010027446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015700.1", "url": "https://www.ensembl.org/id/ENSGALP00010015700.1" } ] } }, { "isoform_ac": "A0A8V0Y9P3-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A8V0Y9P3-1", "sequence": { "sequence": "MRRGIARAAAMQASPHCPANVPQPSSEEVTSGADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 456, "header": "tr|A0A8V0Y9P3-1|A0A8V0Y9P3_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79192208, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027445.1", "url": "https://www.ensembl.org/id/ENSGALT00010027445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015699.1", "url": "https://www.ensembl.org/id/ENSGALP00010015699.1" } ] } }, { "isoform_ac": "A0A8V0YB72-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A8V0YB72-1", "sequence": { "sequence": "MQASPHCPANVPQPSSEEVTSGADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 446, "header": "tr|A0A8V0YB72-1|E1C2X1_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79164108, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027443.1", "url": "https://www.ensembl.org/id/ENSGALT00010027443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015697.1", "url": "https://www.ensembl.org/id/ENSGALP00010015697.1" } ] } }, { "isoform_ac": "A0A8V0YI33-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A8V0YI33-1", "sequence": { "sequence": "MCWKHKFASLCLHLFHCVATLDSNADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 448, "header": "tr|A0A8V0YI33-1|A0A8V0YI33_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79110683, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027432.1", "url": "https://www.ensembl.org/id/ENSGALT00010027432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015686.1", "url": "https://www.ensembl.org/id/ENSGALP00010015686.1" } ] } }, { "isoform_ac": "A0A8V0YI41-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#A0A8V0YI41-1", "sequence": { "sequence": "MCNTAVANGGSALHPKMRGIARAAAMQASPHCPANVPQPSSEEVTSGADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 471, "header": "tr|A0A8V0YI41-1|E1C2X1_CHICK Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=1 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79164266, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027442.1", "url": "https://www.ensembl.org/id/ENSGALT00010027442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015696.1", "url": "https://www.ensembl.org/id/ENSGALP00010015696.1" } ] } }, { "isoform_ac": "E1C2X1-1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1/entry#E1C2X1-1", "sequence": { "sequence": "MIDQADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNEPYSQGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVTPRRIFANGHTYHVNSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRASALCDKHSKLYEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMETKPVETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAILKPRRVCVGGKRRKDDISVDSLDFTKKILHTAWHPTENIIAIAATNNLYIFQDKVNSEMH", "length": 428, "header": "tr|E1C2X1-1|E1C2X1_CHICK Isoform 1 of Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B OS=Gallus gallus OX=9031 GN=PPP2R2C PE=3 SV=2 CANONICAL=E1C2X1-1" }, "locus": { "chromosome": "4", "start_pos": 79140358, "end_pos": 79058526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027440.1", "url": "https://www.ensembl.org/id/ENSGALT00010027440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015694.1", "url": "https://www.ensembl.org/id/ENSGALP00010015694.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422858", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422858", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S8K9-1", "protein_name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "gene_name": "PPP2R2C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEDTDTRKINHSFLRDHSYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNTPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRVFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH", "length": 447 }, "evidence": [ { "id": "E1C2X1", "url": "https://omabrowser.org/oma/group/E1C2X1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BG02-1", "protein_name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "gene_name": "Ppp2r2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGEDTDTRKINHSFLRDHSYVTEADVISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRTFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYESDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH", "length": 447 }, "evidence": [ { "id": "E1C2X1", "url": "https://omabrowser.org/oma/group/E1C2X1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2T4-1", "protein_name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "gene_name": "PPP2R2C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEDTDTRKINHSFLRDHSYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH", "length": 447 }, "evidence": [ { "id": "E1C2X1", "url": "https://omabrowser.org/oma/group/E1C2X1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C2X1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "E1C2X1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "E1C2X1", "url": "https://www.uniprot.org/uniprotkb/E1C2X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NGX8-1", "uniprot_ac": "F1NGX8", "uniprot_id": "F1NGX8_CHICK", "mass": { "chemical_mass": 34008.0, "monoisotopic_mass": 34008.0 }, "refseq": { "ac": "NP_001186545", "name": "solute carrier family 35 member E3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186545" }, "gene_names": [ { "name": "SLC35E3", "type": "recommended", "evidence": [ { "id": "F1NGX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" } ] }, { "name": "SLC35E3", "type": "synonym", "evidence": [ { "id": "NP_001186545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186545" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member E3", "type": "synonym", "evidence": [ { "id": "F1NGX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGX8/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member E3", "type": "synonym", "evidence": [ { "id": "NP_001186545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186545" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.268642.1, SRR13267661.14501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Dec 12, 2010 this sequence version replaced XP_416083.2. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186545" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGX8", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC35E3", "url": "https://www.uniprot.org/uniprotkb/F1NGX8", "locus": { "chromosome": "1", "start_pos": 35417803, "end_pos": 35401015, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012662", "url": "https://www.ensembl.org/id/ENSGALG00010012662" } ] } } ], "crossref": [ { "id": "F1NGX8", "url": "https://alphafold.ebi.ac.uk/entry/F1NGX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009940", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009940", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417842", "url": "https://www.ncbi.nlm.nih.gov/gene/417842", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417842", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417842", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WMVVNTL", "url": "https://omabrowser.org/oma/group/WMVVNTL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA19", "url": "https://www.orthodb.org/?gene=A0A8V0YA19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YID7", "url": "https://www.orthodb.org/?gene=A0A8V0YID7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YN74", "url": "https://www.orthodb.org/?gene=A0A8V0YN74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGX8", "url": "https://www.orthodb.org/?gene=F1NGX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YID7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YID7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YN74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YN74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGX8", "url": "https://www.uniprot.org/uniprotkb/F1NGX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGX8-1", "url": "https://www.uniprot.org/uniprotkb/F1NGX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWMPAQGRLAAGLLVNLAASICIVFLNKWLYVRLGFPNLSLTLVHFAITWLGLYLCQALGAFAPKSLRAAQVLPLALSFCGFVVFTNLSLQSNTIGTYQLAKAMTTPVIVLIQSLAYGKSFPLRIKLTLVPITLGVFLNSYYDVKFNVLGTVFATLGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLFIIPFFEPVFGEGGIFGPWTLSAVIMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLLGGCLLFKDPLSVNQGLGILCTLFGILAYTHFKLSEQENSKSKLVQRP", "length": 309, "header": "tr|F1NGX8-1|F1NGX8_CHICK Isoform 1 of Solute carrier family 35 member E3 OS=Gallus gallus OX=9031 GN=SLC35E3 PE=4 SV=2 CANONICAL=F1NGX8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA19-1", "url": "https://www.uniprot.org/uniprotkb/F1NGX8/entry#A0A8V0YA19-1", "sequence": { "sequence": "MGWMPAQGRLAAGLLVNLAASICIVFLNKWLYVRLGFPNLSLTLVHFAITWLGLYLCQALGAFAPKSLRAAQVLPLALSFCGFVVFTNLSLQSNTIGTYQLAKAMTTPVIVLIQSLAYGKSFPLRIKLTLVRAGEVGGGAGAAPSQPRRPTTPLRPAGAHHARRLPQLLLRREVQRPRHGVRHAGRPGHLSLPSGRYRRGRGARAGCAVGAAAPLRAERAVPRGVSGARLSLPAVALLCRRSYGVSLSC", "length": 249, "header": "tr|A0A8V0YA19-1|F1NGX8_CHICK Computationally mapped isoform of Solute carrier family 35 member E3 OS=Gallus gallus OX=9031 GN=SLC35E3 PE=4 SV=1 CANONICAL=F1NGX8-1" }, "locus": { "chromosome": "1", "start_pos": 35405047, "end_pos": 35404301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030291.1", "url": "https://www.ensembl.org/id/ENSGALT00010030291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017568.1", "url": "https://www.ensembl.org/id/ENSGALP00010017568.1" } ] } }, { "isoform_ac": "A0A8V0YID7-1", "url": "https://www.uniprot.org/uniprotkb/F1NGX8/entry#A0A8V0YID7-1", "sequence": { "sequence": "MGWMPAQGRLAAGLLVNLAASICIVFLNKWLYVRLGFPNLSLTLVHFAITWLGLYLCQALGAFAPKSLRAAQVLPLALSFCGFVVFTNLSLQSNTIGTYQLAKAMTTPVIVLIQSLAYGKSFPLRIKLTLVPITLGVFLNSYYDVKFNVLGTVFATLGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLFIIPFFEPVFGEGGIFGPWTLSAVVLRYNMFGHFKFCITLLGGCLLFKDPLSVNQGLGILCTLFGILAYTHFKLSEQENSKSKLVQRP", "length": 284, "header": "tr|A0A8V0YID7-1|F1NGX8_CHICK Computationally mapped isoform of Solute carrier family 35 member E3 OS=Gallus gallus OX=9031 GN=SLC35E3 PE=4 SV=1 CANONICAL=F1NGX8-1" }, "locus": { "chromosome": "1", "start_pos": 35404445, "end_pos": 35401117, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030287.1", "url": "https://www.ensembl.org/id/ENSGALT00010030287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017566.1", "url": "https://www.ensembl.org/id/ENSGALP00010017566.1" } ] } }, { "isoform_ac": "A0A8V0YN74-1", "url": "https://www.uniprot.org/uniprotkb/F1NGX8/entry#A0A8V0YN74-1", "sequence": { "sequence": "MGWMPAQGRLAAGLLVNLAASICIVFLNKWLYVRLGFPNLSLTLVHFAITWLGLYLCQALGAFAPKSLRAAQVLPLALSFCGFVVFTNLSLQSNTIGTYQLAKAMTTPVIVLIQSLAYGKSFPLRIKLTLVPITLGVFLNSYYDVKFNVLGTVFATLGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLFIIPFFEPVFGEGGIFGPWTLSAVAFIHWQTTDNIKNFSSCLATRSCIQQLDVEVAFHQDTPEQR", "length": 261, "header": "tr|A0A8V0YN74-1|F1NGX8_CHICK Computationally mapped isoform of Solute carrier family 35 member E3 OS=Gallus gallus OX=9031 GN=SLC35E3 PE=4 SV=1 CANONICAL=F1NGX8-1" }, "locus": { "chromosome": "1", "start_pos": 35416799, "end_pos": 35401117, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030294.1", "url": "https://www.ensembl.org/id/ENSGALT00010030294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017569.1", "url": "https://www.ensembl.org/id/ENSGALP00010017569.1" } ] } }, { "isoform_ac": "F1NGX8-1", "url": "https://www.uniprot.org/uniprotkb/F1NGX8/entry#F1NGX8-1", "sequence": { "sequence": "MGWMPAQGRLAAGLLVNLAASICIVFLNKWLYVRLGFPNLSLTLVHFAITWLGLYLCQALGAFAPKSLRAAQVLPLALSFCGFVVFTNLSLQSNTIGTYQLAKAMTTPVIVLIQSLAYGKSFPLRIKLTLVPITLGVFLNSYYDVKFNVLGTVFATLGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLFIIPFFEPVFGEGGIFGPWTLSAVIMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLLGGCLLFKDPLSVNQGLGILCTLFGILAYTHFKLSEQENSKSKLVQRP", "length": 309, "header": "tr|F1NGX8-1|F1NGX8_CHICK Isoform 1 of Solute carrier family 35 member E3 OS=Gallus gallus OX=9031 GN=SLC35E3 PE=4 SV=2 CANONICAL=F1NGX8-1" }, "locus": { "chromosome": "1", "start_pos": 35404445, "end_pos": 35401117, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030290.1", "url": "https://www.ensembl.org/id/ENSGALT00010030290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017567.1", "url": "https://www.ensembl.org/id/ENSGALP00010017567.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417842", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417842", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R659-1", "protein_name": "Solute carrier family 35 member E3", "gene_name": "SLC35E3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASLADRVRGNGRIAAGLLLNLLVSICIVFLNKWIYVHHGFPNMSLTLVHFVVTWLGLYACQKLDIFAPKSLPPSKLLLLALSFCGFVVFTNLSLQNNTIGTYQLAKAMTTPVIIVIQTLFYKKTFSVKIQLTLIPITLGVILNSYYDVKFNFLGMVFAALGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFGEGGIFGPWSLSALLMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLFGGYVLFKDPLSINQGLGMLCTLFGILAYTHFKLSEQEGSKSKLVQRP", "length": 313 }, "evidence": [ { "id": "F1NGX8", "url": "https://omabrowser.org/oma/group/F1NGX8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4IFK2-1", "protein_name": "Solute carrier family 35 member E3", "gene_name": "SLC35E3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASLADRVRGNGRIAAGLLLNLLVSICIVFLNKWIYVHYGFPNMSLTLVHFVVTWLGLYVCQKLDIFAPKSLPPSKLLLLALSFCGFVVFTNLSLQNNTIGTYQLAKAMTTPVIIVIQTLCYKKTFSTKIRLTLIPITLGVILNSYYDVKFNFLGTVFAALGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFAEGGIFGPWSVSALLMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLFGGYVLFKDPLSINQGLGMLCTLFGILAYTHFKLSEQEGSKSKLVQRP", "length": 313 }, "evidence": [ { "id": "F1NGX8", "url": "https://omabrowser.org/oma/group/F1NGX8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q1JQ66-1", "protein_name": "Solute carrier family 35 member E3", "gene_name": "slc35e3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATRLSDLFGNSRIIAGLLVNLLSSICIVFINKWIYVHYGFPNMTLTLIHFVMTWLGLFICQKMDIFAPKSLRPSKILLLALSFCGFVVFTNLSLQSNTIGTYQLAKVMTTPVIIAIQTMYYRKTFSTKIKLTLVPITLGVILNSYYDVRFNLMGMIFATLGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAFLLVLVPFFEPLTGDGGIFGPWSFLALFMVLLSGVIAFLVNLSIYWIIGNTSPVTYNMFGHFKFCITLLGGYVLFQDPLSLNQGLGILCTLTGILAYTHFKLAEQEEGKSRLTQRP", "length": 313 }, "evidence": [ { "id": "F1NGX8", "url": "https://omabrowser.org/oma/group/F1NGX8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PGC7-1", "protein_name": "Solute carrier family 35 member E3", "gene_name": "Slc35e3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLADRVRGNGRIAAGLLFNLLVSICIVFLNKWIYVHHGFPNMSLTLVHFVVTWLGLYICQKLNIFAPKSLPLSKLLLLALSFCGFVVFTNLSLQNNTIGTYQLAKAMTTPVIIAIQTFWYQKRFSVRIQLTLIPITVGVILNSYYDVKFHSLGMVFAALGVVVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFAEGGIFGPWSVSALLMVLLSGIIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLCGGYILFKDPLSVNQGLGILCTLFGILTYTHFKLSEQEGSKSKLVQRP", "length": 313 }, "evidence": [ { "id": "F1NGX8", "url": "https://omabrowser.org/oma/group/F1NGX8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z769-1", "protein_name": "Solute carrier family 35 member E3", "gene_name": "SLC35E3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLVDRVRGHWRIAAGLLFNLLVSICIVFLNKWIYVYHGFPNMSLTLVHFVVTWLGLYICQKLDIFAPKSLPPSRLLLLALSFCGFVVFTNLSLQNNTIGTYQLAKAMTTPVIIAIQTFCYQKTFSTRIQLTLIPITLGVILNSYYDVKFNFLGMVFAALGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFGEGGIFGPWSVSALLMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLFGGYVLFKDPLSINQALGILCTLFGILAYTHFKLSEQEGSRSKLAQRP", "length": 313 }, "evidence": [ { "id": "F1NGX8", "url": "https://omabrowser.org/oma/group/F1NGX8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NGX8", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NGX8", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "F1NGX8", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "antiporter activity", "id": "GO:0015297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015297", "evidence": [ { "database": "UniProtKB", "id": "F1NGX8", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" } ], "pmid": "" }, { "name": "nucleotide-sugar transmembrane transporter activity", "id": "GO:0005338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005338", "evidence": [ { "database": "UniProtKB", "id": "F1NGX8", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGX8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 309, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGX8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGX8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NGX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGX8" }, { "id": "PF03151", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sugar phosphate transporter", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 290, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C041-1", "uniprot_ac": "E1C041", "uniprot_id": "E1C041_CHICK", "mass": { "chemical_mass": 49687.0, "monoisotopic_mass": 49687.0 }, "refseq": { "ac": "NP_001186554", "name": "carboxypeptidase M precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186554" }, "gene_names": [ { "name": "CPM", "type": "recommended", "evidence": [ { "id": "E1C041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ] }, { "name": "CPM", "type": "synonym", "evidence": [ { "id": "NP_001186554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186554" } ] } ], "protein_names": [ { "name": "Carboxypeptidase M", "type": "synonym", "evidence": [ { "id": "E1C041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C041/entry#names_and_taxonomy" } ] }, { "name": "carboxypeptidase M precursor", "type": "synonym", "evidence": [ { "id": "NP_001186554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186554" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01066092.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Dec 11, 2010 this sequence version replaced XP_416085.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186554" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPM", "url": "https://www.uniprot.org/uniprotkb/E1C041", "locus": { "chromosome": "1", "start_pos": 35436609, "end_pos": 35471464, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012705", "url": "https://www.ensembl.org/id/ENSGALG00010012705" } ] } } ], "crossref": [ { "id": "E1C041", "url": "https://alphafold.ebi.ac.uk/entry/E1C041", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009945", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009945", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03866", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03866", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11308", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11308", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417843", "url": "https://www.ncbi.nlm.nih.gov/gene/417843", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417843", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417843", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHEPYLT", "url": "https://omabrowser.org/oma/group/GHEPYLT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA74", "url": "https://www.orthodb.org/?gene=A0A8V0YA74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIJ4", "url": "https://www.orthodb.org/?gene=A0A8V0YIJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C041", "url": "https://www.orthodb.org/?gene=E1C041", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11532:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11532:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C041-1", "url": "https://www.uniprot.org/uniprotkb/E1C041-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTGAGEAVGVLCLVSLVAALDYKYHHSEELEAYLKEVHAAYPALTHLHSIGRSVEGRDLWVLVLGRFPTQHKIGIPEFKYVANMHGDETVGREILLHLIDHLVTNYGRDPVITRLLNNTRIHIMPTMNPDGFEATVVPDCYYSRGRYNKNGEDLNRNFPDAFENNNNLIQPETQAVINWIKNETFVLSANLHGGALVASYTFDNGNSVTGTSNGYSRSPDDDVFIHLAKTYSFNHASMYKGTGCDSKQTFPDGITNGYSWYQLEGGMQDYNYVWGQCFEITLELSCCKYPPAEQLEKFWRDNKVALVEYIKQVHLGVKGQVTDKNGNPIPNAIVEAKGRPHICPYRTNEHGEYFLLLLPGKYVINATVPGFKSMLKTVDIPDNTANFSALKQDFSFPEVSVKPRPASCPRTPLYQELERSSAAVKPTLHILVLVIVTISILK", "length": 443, "header": "tr|E1C041-1|E1C041_CHICK Isoform 1 of Carboxypeptidase M OS=Gallus gallus OX=9031 GN=CPM PE=1 SV=1 CANONICAL=E1C041-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA74-1", "url": "https://www.uniprot.org/uniprotkb/E1C041/entry#A0A8V0YA74-1", "sequence": { "sequence": "MAAPARRWGCSCEERWQHADGRWGGGGRPLPGLSGGRAGLQVPPQRGAGGVPEGGARRLPGPHPPAQHRPLGGSRLKRKPMLLLQTVGREILLHLIDHLVTNYGRDPVITRLLNNTRIHIMPTMNPDGFEATVVPDCYYSRGRYNKNGEDLNRNFPDAFENNNNLIQPETQAVINWIKNETFVLSANLHGGALVASYTFDNGNSVTGTSNGYSRSPDDDVFIHLAKTYSFNHASMYKGTGCDSKQTFPDGITNGYSWYQLEGGMQDYNYVWGQCFEITLELSCCKYPPAEQLEKFWRDNKVALVEYIKQVHLGVKGQVTDKNGNPIPNAIVEAKGRPHICPYRTNEHGEYFLLLLPGKYVINATVPGFKSMLKTVDIPDNTANFSALKQDFSFPEVSVKPRPASCPRTPLYQELERSSAAVKPTLHILVLVIVTISILK", "length": 439, "header": "tr|A0A8V0YA74-1|E1C041_CHICK Computationally mapped isoform of Carboxypeptidase M OS=Gallus gallus OX=9031 GN=CPM PE=1 SV=1 CANONICAL=E1C041-1" }, "locus": { "chromosome": "1", "start_pos": 35471460, "end_pos": 35440263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030396.1", "url": "https://www.ensembl.org/id/ENSGALT00010030396.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017629.1", "url": "https://www.ensembl.org/id/ENSGALP00010017629.1" } ] } }, { "isoform_ac": "A0A8V0YIJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1C041/entry#A0A8V0YIJ4-1", "sequence": { "sequence": "MQLRKCFQYWYALLKWIKECLRDCVGTAVYLQKNLPRSNSYHPVSPQCFVRLKRKPMLLLQTVGREILLHLIDHLVTNYGRDPVITRLLNNTRIHIMPTMNPDGFEATVVPDCYYSRGRYNKNGEDLNRNFPDAFENNNNLIQPETQAVINWIKNETFVLSANLHGGALVASYTFDNGNSVTGTSNGYSRSPDDDVFIHLAKTYSFNHASMYKGTGCDSKQTFPDGITNGYSWYQLEGGMQDYNYVWGQCFEITLELSCCKYPPAEQLEKFWRDNKVALVEYIKQVHLGVKGQVTDKNGNPIPNAIVEAKGRPHICPYRTNEHGEYFLLLLPGKYVINATVPGFKSMLKTVDIPDNTANFSALKQDFSFPEVSVKPRPASCPRTPLYQELERSSAAVKPTLHILVLVIVTISILK", "length": 415, "header": "tr|A0A8V0YIJ4-1|E1C041_CHICK Computationally mapped isoform of Carboxypeptidase M OS=Gallus gallus OX=9031 GN=CPM PE=1 SV=1 CANONICAL=E1C041-1" }, "locus": { "chromosome": "1", "start_pos": 35458034, "end_pos": 35440263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030391.1", "url": "https://www.ensembl.org/id/ENSGALT00010030391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017627.1", "url": "https://www.ensembl.org/id/ENSGALP00010017627.1" } ] } }, { "isoform_ac": "E1C041-1", "url": "https://www.uniprot.org/uniprotkb/E1C041/entry#E1C041-1", "sequence": { "sequence": "MRTGAGEAVGVLCLVSLVAALDYKYHHSEELEAYLKEVHAAYPALTHLHSIGRSVEGRDLWVLVLGRFPTQHKIGIPEFKYVANMHGDETVGREILLHLIDHLVTNYGRDPVITRLLNNTRIHIMPTMNPDGFEATVVPDCYYSRGRYNKNGEDLNRNFPDAFENNNNLIQPETQAVINWIKNETFVLSANLHGGALVASYTFDNGNSVTGTSNGYSRSPDDDVFIHLAKTYSFNHASMYKGTGCDSKQTFPDGITNGYSWYQLEGGMQDYNYVWGQCFEITLELSCCKYPPAEQLEKFWRDNKVALVEYIKQVHLGVKGQVTDKNGNPIPNAIVEAKGRPHICPYRTNEHGEYFLLLLPGKYVINATVPGFKSMLKTVDIPDNTANFSALKQDFSFPEVSVKPRPASCPRTPLYQELERSSAAVKPTLHILVLVIVTISILK", "length": 443, "header": "tr|E1C041-1|E1C041_CHICK Isoform 1 of Carboxypeptidase M OS=Gallus gallus OX=9031 GN=CPM PE=1 SV=1 CANONICAL=E1C041-1" }, "locus": { "chromosome": "1", "start_pos": 35471408, "end_pos": 35440263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030409.1", "url": "https://www.ensembl.org/id/ENSGALT00010030409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017634.1", "url": "https://www.ensembl.org/id/ENSGALP00010017634.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417843", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417843", "resource": "KEGG Pathway" }, { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "B7Z0Z5-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG4678", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MILRTPLVAGHQLQLLLLPSVLLLMLHLLLCDAKTVNPGDSMQMQHHQMTAEPGLPEPRAYMPDAQHLDFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVKYVGNIHGNEPVGREMLLHLIQYFVTSYNTDQYVKWLLDNTRIHILPTMNPDGYAVSKEGTCDGGQGRYNARGFDLNRNFPDYFKQNNKRGQPETDSVKDWISKIQFVLSGSLHGGALVASYPYDNTPNSRLLKGICRSSALCAMFQTYSAAPSLTPDDDVFKHLSLVYARNHAKMSRGVACKSATPAFENGITNGAAWYPLTGGMQDYNYVWYGCMEITLEISCCKFPPAYELKKYWEDNQLSLIKFLAEAHRGVQGFVFDPAGMPIERASIKIKGRDVGFQTTKYGEFWRILLPGYYKVEVFAEGFAPREVEFVIVEQHPTLLNVTLQPSKRLEGIGPMGPGGVPVGGVVGPGGLYRPIPSPQHYRPPVPPYAGAASSDSGIFSTISNGLNSLYSNIFG", "length": 527 }, "evidence": [ { "id": "E1C041", "url": "https://omabrowser.org/oma/group/E1C041/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "I3LTE1-1", "protein_name": "Carboxypeptidase M", "gene_name": "CPM", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDCASLWLVLLLPVVAALDFRYHHQQEMEAFLKKVAQDYSSITHLHSIGKSVEGRNLWVLIVGHSPKEHRIGIPEFKYVANMHGDESVGRELLLHFIEYLVTSNGRDPEVTNLINNTRIHIMPSMNPDGFEAVLNPDCFYNKGRENSNSYDLNRNFPDAFEFNNVSRQPETVAVMKWLNTETFVLSANLHGGALVASYPFDNGVPATGTLYSRSLTPDDDVFQYLAHTYASKNPDMKKRKPCKTKIDSPSGIVNGYFWYPLKGGMQDYNYIWAQCFEITLELSCCKYPREEKLPGFWNDNKDSLLEYMKQVHIGVKGQVFDQNETPLPNVIVEVQDRKHICPYRTNKFGEYYLLLLPGSYVIEVTVPGHNPHLTKVTIPPKSQNFSALKKDILLPFRGQLDHIPESNPLCPMIPLYRDLQGHSVATKPSLFLFLVTLFHILFK", "length": 443 }, "evidence": [ { "id": "E1C041", "url": "https://omabrowser.org/oma/group/E1C041/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P14384-1", "protein_name": "Carboxypeptidase M", "gene_name": "CPM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLPDHSAATKPSLFLFLVSLLHIFFK", "length": 443 }, "evidence": [ { "id": "E1C041", "url": "https://omabrowser.org/oma/group/E1C041/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80V42-1", "protein_name": "Carboxypeptidase M", "gene_name": "Cpm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRARLWLGLLLPVVAALDFRYHHQEGMEAFLKSVAQNYSSITHLHSIGKSVRGRNLWVLVVGQTPKEHRVGIPEFKYVANMHGDETVGRELLLHLIDYLVSSYRKDPEITHLIDSTRIHIMPSMNPDGFEAVQKPDCYYSNGRENYNNYDLNRNFPDAFENNNVTKQPETLAIMEWLKTETFVLSANLHGGALVASYPFDNGVQATGTLLSRSLTPDDDVFQHLAYTYASRNPNMTKGDQCKNKRNFPNGIINGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPLFWNDNKASLIEYIKQVHLGVKGQVFDQSGAPLPNVIVEVQDRKHICPFRTNKLGEYYLLLLPGSYVINVTVPGHDSYLTKLTIPGKSQPFSALKKDFHLPLRWQPDSISVSNPSCPMIPLYKFMPSHSAATKPSLGVFFMTLLYVFFK", "length": 443 }, "evidence": [ { "id": "E1C041", "url": "https://omabrowser.org/oma/group/E1C041/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ], "pmid": "" }, { "name": "peptide metabolic process", "id": "GO:0006518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006518", "evidence": [ { "database": "UniProtKB", "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1C041", "url": "https://www.uniprot.org/uniprotkb/E1C041" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C041-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 443, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C041-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C041" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C041" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 314, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 387, "end_pos": 389 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C576-1", "uniprot_ac": "E1C576", "uniprot_id": "E1C576_CHICK", "mass": { "chemical_mass": 174629.0, "monoisotopic_mass": 174629.0 }, "refseq": { "ac": "XP_004949445", "name": "tetratricopeptide repeat protein 37", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949445" }, "gene_names": [ { "name": "TTC37", "type": "recommended", "evidence": [ { "id": "E1C576", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ] }, { "name": "TTC37", "type": "synonym", "evidence": [ { "id": "XP_004949445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949445" } ] } ], "protein_names": [ { "name": "SKI3 subunit of superkiller complex", "type": "synonym", "evidence": [ { "id": "E1C576", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C576/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 37", "type": "synonym", "evidence": [ { "id": "XP_004949445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949445" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC37", "url": "https://www.uniprot.org/uniprotkb/E1C576", "locus": {} } ], "crossref": [ { "id": "ENSGALG00000014670", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014670", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "427114", "url": "https://www.ncbi.nlm.nih.gov/gene/427114", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427114", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427114", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQWELDP", "url": "https://omabrowser.org/oma/group/CQWELDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YIK3", "url": "https://www.orthodb.org/?gene=A0A8V0YIK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C576", "url": "https://www.orthodb.org/?gene=E1C576", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15704", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15704", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15704:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15704:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004949445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YIK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YIK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C576-1", "url": "https://www.uniprot.org/uniprotkb/E1C576-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNKEVKAALKSAREAIRNKEYKEALKHCKAVLKQEKNNYNAWVFIGLAAAELEQPDQAKGAYKKAIELEPNQLLAWQGLANLYEKSNQPDVQGDLGDVYQKLLELYESGDKQKWCDVCNKLVELYCQGNKYLEAAELWQKLTEVKKEGGAEKAELHRLWKRMIQLLGDNVQYQDNKTAQLLFNAYEEALNSADTVPSEDHRNLYKDFIQCLSKFPHEAARLEKACDDMMALYPTVSYPLEVLCLYFIQSGTLSEEALQYFSKLLEMDSSSGPGIIGFGIKCLQEKKYNEAIKSLTEGLQKVSQCPGAWHYLAEAQMKVHRHRDAVLSCNQALKNLETPEGPSLQRKNLILQLKAEALIKIADAGAAEEAINALKQIVGASSDPVLLAFRGRAYLNKGLVDEASKISQELLLSYPDLAEAHALEGFIHYSQKKYEQAERSFQNAIERRAEIAEYHQYLGLTYWFMSDETKRDKGKTLTHFLKAAKLDSYLGSAFCYLGNYYRDVAGDKSRARGCYKKAFELDGTDEESGTAAVDLSVELGDTDTALSILNEVTEKANAGAAKWAWLHRGLYYLRTGQPSKAVADLQAALRADRMDPNCWESLGEAYVSRGSYAAALKSFRKASELNPDHVYSIYRAAAVEQILGKYENAIVTYQQILEKTEEYVPALKGLGECYLMLARSALEKYLDMRAVGYIEQALEFFTRATKQRPDISSLWKLLGDTCTSVHVISPTKVNVQVLGSLLGKNENKQMLKKSELLRLGGRCYGRALKLIPLPNIWCDLGINYYRQAEHLTAVGTDMNEIRELLEKSLQCLKKAVRLDSKNHLYWNALGVVASCSVIGNYALAQHSFIKSVQAEEINVVAWTNLGVLYLATGNIEQAHEAFKVAQSLEPSYLMCWIGQALVAEAIGSYDTMDLFRHTTELSTHTEGAKGYAHWVCSTLQDKSNRDTEQYLYNIVEMNAIPAAQVVMSKYTERNPDDASAFTMLGYLNDYLELKRQAKDAYERAATLLKNSEDTEKYNTAMQNYGRSLCAIGECDKAIEVYTSIPLTEFDAIMGIALAYFKKGLLEESIKAYEKALSVAKSEQDKTHTLTALAIIEYKRNKVDAAKTLLFKCSLKEPSTESLKALCTLGLVKQDVTLATAALKELLKHEKGSDGIYERCLIASAVYALQGRNLGIQREVSKAIHSYPGNPALWSLLSRLIPLYTPQKAKGGAVAGNIAHALDLRHGKDVLRNVAVNQLAAGCHMLEDERNNPLKNIQKAIHICPDNPAAWAVLMAACHAENTVVCLNNTQPKRTDLEMTLVSTISAKTGENNLPHNYIQTLENWSLCQAITSLEESGRISEAEALCTKGLKNCPEHPALFLLLRQIQCKQLLLSHKELPDTILKELHKTVMTSSSSIAAWQWLAKVYQSQGMIVGAEMCYRKSLQLASQQGSWSGKLSSLLRLAMLALEVCMANVSNEHWPSLVQEATTEALKLYSCPLAVLLQALLQYIRKMGARETRRMLERVVYQPGNPETIVSVARWYLLQHLYAKDDYELIDVLVENAKANGDIRALDLHKKLSASA", "length": 1562, "header": "tr|E1C576-1|E1C576_CHICK Isoform 1 of SKI3 subunit of superkiller complex OS=Gallus gallus OX=9031 GN=TTC37 PE=1 SV=3 CANONICAL=E1C576-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YIK3-1", "url": "https://www.uniprot.org/uniprotkb/E1C576/entry#A0A8V0YIK3-1", "sequence": { "sequence": "MSNKEVKAALKSAREAIRNKEYKEALKHCKAVLKQEKNNYNAWVFIGLAAAELEQPDQAKGAYKKAIELEPNQLLAWQGLANLYEKSNQPDVQGDLGDVYQKLLELYESGDKQKWCDVCNKLVELYCQGNKYLEAAELWQKLTEVKKEGGAEKAELHRLWKRMIQLLGDNVQYQDNKTAQLLFNAYEEALNSADTVPSEDHRNLYKDFIQCLSKFPHEAARLEKACDDMMALYPTVSYPLEVLCLYFIQSGTLSEEALQYFSKLLEMDSSSGPGIIGFGIKCLQEKKYNEAIKSLTEGLQKVSQCPGAWHYLAEAQMKVHRHRDAVLSCNQALKNLETPEGPSLQRKNLILQLKAEALIKIADAGAAEEAINALKQIVGASSDPVLLAFRGRAYLNKGLVDEASKISQELLLSYPDLAEAHALEGFIHYSQKKYEQAERSFQNAIERRAEIAEYHQYLGLTYWFMSDETKRDKGKTLTHFLKAAKLDSYLGSAFCYLGNYYRDVAGDKSRARGCYKKAFELDGTDEESGTAAVDLSVELGDTDTALSILNEVTEKANAGAAKWAWLHRGLYYLRTGQPSKAVADLQAALRADRMDPNCWESLGEAYVSRGSYAAALKSFRKASELNPDHVYSIYRAAAVEQILGKYENAIVTYQQILEKTEEYVPALKGLGECYLMLARSALEKYLDMRAVGYIEQALEFFTRATKQRPDISSLWKLLGDTCTSVHVISPTKVNVQVLGSLLGKNENKQMLKKSELLRLGGRCYGRALKLIPLPNIWCDLGINYYRQAEHLTAVGTDMNEIRELLEKSLQCLKKAVRLDSKNHLYWNALGVVASCSVIGNYALAQHSFIKSVQAEEINVVAWTNLGVLYLATGNIEQAHEAFKVAQSLEPSYLMCWIGQALVAEAIGSYDTMDLFRHTTELSTHTEGAKGYAHWVCSTLQDKSNRDTEQYLYNIVEMNAIPAAQVVMSKYTERNPDDASAFTMLGYLNDYLELKRQAKDAYERAATLLKNSEDTEKYNTAMQNYGRSLCAIGECDKAIEVYTSIPLTEFDAIMGIALAYFKKGLLEESIKAYEKALSVAKSEQDKTHTLTALAIIEYKRNKVDAAKTLLFKCSLKEPSTESLKALCTLGLVKQDVTLATAALKELLKHEKGSDGIYERCLIASAVYALQGRNLGIQREVSKAIHSYPGNPALWSLLSRLIPLYTPQKAKGGAVAGNIAHALDLRHGKDVLRNVAVNQLAAGCHMLEDERNNPLKNIQKAIHICPDNPAAWAVLMAACHAENTVVCLNNTQPKRTDLEMTLVSTISAKTGENNLPHNYIQTLENWSLCQAITSLEESGRISEAEALCTKGLKNCPEHPALFLLLRQIQCKQLLLSHKELPDTILKELHKTVMTSSSSIAAWQVSVYSLSNFGISAVR", "length": 1416, "header": "tr|A0A8V0YIK3-1|E1C576_CHICK Computationally mapped isoform of SKI3 subunit of superkiller complex OS=Gallus gallus OX=9031 GN=TTC37 PE=1 SV=1 CANONICAL=E1C576-1" }, "locus": { "chromosome": "Z", "start_pos": 58275433, "end_pos": 58241790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031475.1", "url": "https://www.ensembl.org/id/ENSGALT00010031475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018379.1", "url": "https://www.ensembl.org/id/ENSGALP00010018379.1" } ] } }, { "isoform_ac": "E1C576-1", "url": "https://www.uniprot.org/uniprotkb/E1C576/entry#E1C576-1", "sequence": { "sequence": "MSNKEVKAALKSAREAIRNKEYKEALKHCKAVLKQEKNNYNAWVFIGLAAAELEQPDQAKGAYKKAIELEPNQLLAWQGLANLYEKSNQPDVQGDLGDVYQKLLELYESGDKQKWCDVCNKLVELYCQGNKYLEAAELWQKLTEVKKEGGAEKAELHRLWKRMIQLLGDNVQYQDNKTAQLLFNAYEEALNSADTVPSEDHRNLYKDFIQCLSKFPHEAARLEKACDDMMALYPTVSYPLEVLCLYFIQSGTLSEEALQYFSKLLEMDSSSGPGIIGFGIKCLQEKKYNEAIKSLTEGLQKVSQCPGAWHYLAEAQMKVHRHRDAVLSCNQALKNLETPEGPSLQRKNLILQLKAEALIKIADAGAAEEAINALKQIVGASSDPVLLAFRGRAYLNKGLVDEASKISQELLLSYPDLAEAHALEGFIHYSQKKYEQAERSFQNAIERRAEIAEYHQYLGLTYWFMSDETKRDKGKTLTHFLKAAKLDSYLGSAFCYLGNYYRDVAGDKSRARGCYKKAFELDGTDEESGTAAVDLSVELGDTDTALSILNEVTEKANAGAAKWAWLHRGLYYLRTGQPSKAVADLQAALRADRMDPNCWESLGEAYVSRGSYAAALKSFRKASELNPDHVYSIYRAAAVEQILGKYENAIVTYQQILEKTEEYVPALKGLGECYLMLARSALEKYLDMRAVGYIEQALEFFTRATKQRPDISSLWKLLGDTCTSVHVISPTKVNVQVLGSLLGKNENKQMLKKSELLRLGGRCYGRALKLIPLPNIWCDLGINYYRQAEHLTAVGTDMNEIRELLEKSLQCLKKAVRLDSKNHLYWNALGVVASCSVIGNYALAQHSFIKSVQAEEINVVAWTNLGVLYLATGNIEQAHEAFKVAQSLEPSYLMCWIGQALVAEAIGSYDTMDLFRHTTELSTHTEGAKGYAHWVCSTLQDKSNRDTEQYLYNIVEMNAIPAAQVVMSKYTERNPDDASAFTMLGYLNDYLELKRQAKDAYERAATLLKNSEDTEKYNTAMQNYGRSLCAIGECDKAIEVYTSIPLTEFDAIMGIALAYFKKGLLEESIKAYEKALSVAKSEQDKTHTLTALAIIEYKRNKVDAAKTLLFKCSLKEPSTESLKALCTLGLVKQDVTLATAALKELLKHEKGSDGIYERCLIASAVYALQGRNLGIQREVSKAIHSYPGNPALWSLLSRLIPLYTPQKAKGGAVAGNIAHALDLRHGKDVLRNVAVNQLAAGCHMLEDERNNPLKNIQKAIHICPDNPAAWAVLMAACHAENTVVCLNNTQPKRTDLEMTLVSTISAKTGENNLPHNYIQTLENWSLCQAITSLEESGRISEAEALCTKGLKNCPEHPALFLLLRQIQCKQLLLSHKELPDTILKELHKTVMTSSSSIAAWQWLAKVYQSQGMIVGAEMCYRKSLQLASQQGSWSGKLSSLLRLAMLALEVCMANVSNEHWPSLVQEATTEALKLYSCPLAVLLQALLQYIRKMGARETRRMLERVVYQPGNPETIVSVARWYLLQHLYAKDDYELIDVLVENAKANGDIRALDLHKKLSASA", "length": 1562, "header": "tr|E1C576-1|E1C576_CHICK Isoform 1 of SKI3 subunit of superkiller complex OS=Gallus gallus OX=9031 GN=TTC37 PE=1 SV=3 CANONICAL=E1C576-1" }, "locus": { "chromosome": "Z", "start_pos": 58282442, "end_pos": 58241790, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031483.1", "url": "https://www.ensembl.org/id/ENSGALT00010031483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018383.1", "url": "https://www.ensembl.org/id/ENSGALP00010018383.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427114", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427114", "resource": "KEGG Pathway" }, { "id": "R-GGA-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZL50-1", "protein_name": "Superkiller complex protein 3", "gene_name": "Skic3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKEVKTALKSARDAIRNKEYKEVLKHCKTVLKQEKDNYNAWVFIGVAAAELGQPDQAQGAYKKAAELEPEQLLAWQGLASLYEKCNHINAKDDLPGVYRKLLDLYESVDKQKWCDVCKKLVDLYHQEKKHLEVARTWYRLIKARQEDGADRQELYELWRKLSQLLSEDAEDQNDETQQMLLTAFENALDLADNVPSEDHQVLYRNFIQYLSKFPHEMTRLKKACEGMITMYPAVQYPLEVICLYLIDSGNLTDEGHQYCYKLVEMNSKSGPGLIGLGIRALQDKKYEDAISHLTEGLKESPLCIAGWCHLAEVQVKVHRPKEAILSCNRALKTIDNLGASGGSLHQKNLCLRLKAEALLKLSDCASLEEAVHILDQLSDTDNTPGLLVLQGLACLNTGAIDKATKIMEDLVASYPDLSEAHALEAYVHFTKKDYVQAETSFQRALEKDAEVAEYHYQLGLTYWLMGEETRKDRTKALNHFLKAARLDAHMGKVFCYLGHYYRDVAGDRNRARGCYRKAFELDDSDAESGAAAVDLSVELEDTETALAILTAVTQKASSGAAKWAWLRRGLYYLKAGHHSQAVADLQAALRADPKDCNCWESLGEAYLSRGSYTTALKSFTRASELSPDSTYSVFKVAAIQQILGRYSEAIAQYQLIIKKEEDYVPALKGLGECHLMLGKAALVDFLDGKAVDYVEQALGYFTRALQHRADVSCLWKLMGDACTCLHPVSPAKVNVRVSGALLGQQEGQEVLRKDELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSSMNDLTELLEKSLHCLKKAVRLDSNNHLYWNALGVVTCYHGVGNYALAQHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFQMAQSLDPSYLLCWIGQALIAERIGSYETMDLFRHTTELSMHTEGAIGYAYWVCTTLQDKSNRETELYQYNILQMNAVPAAQGVLCKYVERIQNYAPAFTMLGYLNEHLQLKREAAEAYQRATALLHSAEDQHTYNVTVRNWGRLLCSIGDYDKALQAFKSTPLAELEDIIGFALALFMKGLYKESSTAYERALTVCKSEQDKAHILTAMAVTEYKQGKMDAAKSLLFKCSILKEPTAESLQVLCALGLAMQDATLSKAALNELLKHIKQKNDYHRYLLTSAIYALQGHSVAVQRQVAKAVHSNPADPALWSLLSRIVAQYTQQNAKGGAVAGSVAHILDSNHGKKALLYTAVNQLAMGGSTAEDKSSTALKTIQKAAFLSPDDPAVWAGLMAACHADDKLALVSNTQPKRVDLYLALQSAVSASLKDKENLQNYNLLLEKWSFSQAVTGLIDTGKISEAESLCTKNLKSNPDQPAVILLLRQVQCTSLLASQKPLPDAVLEELQKTVMSNSTSVPAWQWLAQVYQSQGMMSAAEMCYRKSLQVASQQGSWSGKLSSLLKLALLALEVCMANVSGDHWSSLVQEATSEALKVCFSPLAIFLQALLQFNRKMGARETRRLLERVVYQTGYPNSIVSTARWYLLRHLHAKDDHELIDVLVRNAETHGDKRMLELNRKLSAQ", "length": 1563 }, "evidence": [ { "id": "E1C576", "url": "https://omabrowser.org/oma/group/E1C576/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F2R1-1", "protein_name": "Superkiller complex protein 3", "gene_name": "skic3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRQILLAEWKATKFGLQRIMSSKEVKAELKNAREAIKNKEFKEALKHCKAVLKLEKNNYNAWVFIGVAATELQQPDQAQTAYRKASELEPEQLLAWQGLANLYEKSDQADFKAELPKIYQKLITLYETSDKAKCFEVTKKLVEIYQSEKNYLQVARVWRRLIQVKEDEEGLEDAELLELWKEMTRLLQDTVDDQDNETQQHLISAFERALQMTVDVPSEAHRSLSQDYIKCLSKLPHEVAKLKEVCDATLSHYPTHPYPLEALSEHYIQTGDCSEEAVSCFKRLLELDPNNSYAHFGLGIKACQDKKYEDAIKNIGLGLKRMRFSIIGWYNLALAQLKMHKYSDSAISSSQGLKSSVGNADDWTQKLLRLKLEALVKTGREQDADEALQILALISDAKNDPVVLALKGRAYLEKGQTEEAFQVSTELLSSHPGSVDGLTLKALLHVAKEQHKQAEESFLEALSRSPDSGELFFLLGSLYWNMGEEIRRDRSKTHLLKAAKLDPYLGSVFRLLGHYYREVAKDQGRARGCYKRAFELDPSDAEAGAAAVDLSMEQGDMDSALTVLQSVTERATPGSAKWAWMRRGLYHLKIGQHQQAIADLQAALRADPQDWVCWECLGEAYLNRRSFTAALKAFDKAHVLQPTSIYSLYQTAAIKQILGRFKEAAAEYKQILEKEDYVPALKGLGECLLALAKSALDDYLDGRAVDLIQNAIHYLFRAVKQRPDLSCLWKLLGDSCTASRTVSPNRAKVLVPGALCGMDPSDQKHTLDQRQLLTLGERCFGRALKLMPEAPSLWCDLGLNYYHQSRLLSSHYPEEDPQALLEKALQCVKKAIMLDSANHTYWNALGVVAMTKGIENFALAQHSFIKSVKAEPNNVVAWTNLGALYLKKGNIELSHEAFKIAQSLEPLYVNCWIGQALIAETVGSYDTMDLFRHTTELSTHTEGVKGYAYCVCSTLLDRSNRDSELYLYNIVQMNAVSAAQVALSKYTERIQTDPDAFIMLGYLNTHLQLRKQATEAYHRAVELLQGSLHTDKLSFALRGYGRALSDDGQWEEAVRIYCSTPLEELHDLIGLALACFRIGRLPESIQAYEKALVVASTEKEKAYILTALALIQHKLGSMDHAKTLLFKCSMLKEPVQESLQCLCALGLVHGDVTLASATVTELLKLGEPAGSAVEDRCLLTCTLLALQGNFSGVHREASRAIHRNPGNPSLWALLSRLVPQYCPNKADGGAVAGNVACQASLTLGKRALLYSGVNQLASGRHSGEDRRHNALKTIQRAVLLCPDDPAGWAGLMAACHTENTACFLTGSTPHREDLERAHMALVSEKVKGLQGEDGLLAQALEGWVLQQAVTGLKLSGQYDQAEALCSQVLSVSPEHPVVFLMLRQVQCERLLLSEAGSCIPPAVLDQLSAAVMANHTSVAAWHWLAEVYRSQGLLAQASVAYKQSLQLASQLGDHSGKMSSLLRLSLLALTPCLAGVGVSDWKDLVSEATGEVLKMSKSPVALLFQALLQFSVKMGARETRRLLERIVYASALGGSETIASVARWYLLRHLHAKDDLELIDTLLVKATAAGDSRLVDFHRRLYPSS", "length": 1585 }, "evidence": [ { "id": "E1C576", "url": "https://omabrowser.org/oma/group/E1C576/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F8VPK0-1", "protein_name": "Superkiller complex protein 3", "gene_name": "Skic3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQGAYKKAAELEPEQLLAWQGLASLYEKCNQVNAKDDLPGVYQKLLDLYESADRQKWCDVCKKLVALYHQEKKHLEVARTWHRLIKTRQEDGADRQELYELWRKLSQLLAENIEDQNNETQQMLLTAFENALDLADNIPSEDHQVLYRNFIQCLSKFPHETTKLKKACEEMIAIYPTVQYPLEVICLYLIDSGSLTSEGHQYCCKLVEMNSKSGPGLIGLGIIALQDKKYEDAVRHLTEGLKESPVCIAGWCHLAEAQVKMHRPKEAILSCNQALKTIDNFGASGGNLHQKNLCLRLKAEALLKLSDGASSEEAVRTLDQVSDVDNTPGLLVLQGLACLNTGAVDKATKIMEDLVTSYPDLAEAHALEGRVHFTKKDYVQAEVSFQRALEKDAEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDAHMGKVFCYLGHYYRDVAGDRNRARGCYRKAFELDDNDAESGAAAVDLSLELEDTETALAILTAVTQKASAGAAKWAWLRRGLYHLKAGQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYTTALKSFMKASELNPDSTYSVFKVAAIQQILGRYSEAIAQYQLIIKMKEDYVPALKGLGECHLLLGKVALVDFLDGKAVDYVEQALGYFTRALQHRADVSCLWKLVGDACTCLHPVSPSKVHVHVLGALLGQKEGQEVLKKEELLSLGGRCYGRALKLMSTSNTWCDLGINYYRQVQHLAETGSSMSDLTELLEKSLHCLKKAVRLDSNNHLHWNALGVVACYRGVGNYALAQHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFKMAQSLDPSYLLCWIGQALIAERVGSYDTMDLFRHTTELSMHTEGAIGYAYWVCTTLQDKSNRETELYQYNILEMNAIPAAQGVLCKYVERIQNSASAFTMLGYLNEHLQLKKEAAEAYQRATTLLHSAEDQNTYNVAVRNWGRLLCSIGDYDRAIQAFKSTPLVELEDIIGFALALFMKGLYKESGSAYERALAVCKSEQDKAHILTAMAIVEYKQGKMDAAKSFLFKCSILKEPTAESLQALCALGLAMRDATLSKAALNELLKHIKRRNDYHSCLLMSAIYALQGHSVAVQRQVAKAVHSNPADPALWSLLSRIVAQYTQRSAKGGAVAGNVAHILDLNHGKKALLYTAVNQLAMGSSTAEDKSNTALKTIQKAAFLSPDDPAVWAGLMAACHADDKLALLNNTQPKRVDLYLALRSAVAASLKDKEILQNYNQSLEKWSFSQVVTGLIDTGKTSEAESLCTQSLKSNPDQPAVILLLRQVQCMSLLESQKPLPDAVLEELQKTVMSNSTSVPAWQWLAQVYQSQGMMGAAEMCYRKSLQVASQQGNWSGKLSSLLKLALLALEVCMANVSGDHWSSLVQEATSEALKVCFSPLAVFLQALLQFNRKMGARETRRLLERIVYQTGYPSSIVSAARWYLLRHLYAKDDPELIDVLVRNAETHGDKRILELNRKLSAQ", "length": 1563 }, "evidence": [ { "id": "E1C576", "url": "https://omabrowser.org/oma/group/E1C576/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3H761-1", "protein_name": "Superkiller complex protein 3", "gene_name": "Ttc37", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQGAYKKAAELEPEQLLAWQGLASLYEKCDHENAKGDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLHHQEKRHLEVARTWYKLIKTRQEDGADKQELYELWRKLTKLLAEYIEDQNNETQQMLLTAFENALDLADNIPSEDHQGLYRHFIQCLSKLPHETSRLKNACEGMINIYPTVQYPLEVISLHLIESGSLTDEGQQYCCKLVEMNSKSGPGLIGLGIKALQDKKYEDAVSRLTEGLKEIPLCIAGWCHLAEAQVKVHRPKEAILSCDQALKNIDNHSAAGSRRHQKNLCLLLKAEALLKLSDCESSEEAIRILDQVSDTDNTPGLLVLQGLAHLNTGAVDKATKIMEDLRTSYPDLAEVHALEALIHFTKKDYLQAEACFQRALEQDAEVAEYHYQLGLTYWFMSEETRKDKSKALTHFLKAARLDTYMGKVFCYLGHYYRDIAGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDTETALAILTAVTQKASAGAAKWAWLRRGLYHLKAGQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYTTALKSFIRASELNPDSMYSVFKVAAIQQILGRYTEAIAQYQLIIKKKEDYVPALKGLGECHLMMAKAALVDFLDGKAVDYVEKALEYFTWALQHQADVSCLWKLAGDACTSLHAVSPSTVHVRVLGVLLGQQEGSEVLKKDELLHLGGRCYGRALKLMSTSNTWCDLGINYYHQAQHLAETGSSTDGLTELLEKSVQCLKKAVRLDSNNHLYWNALGVVACYRGIGNYALAQHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFKMAQSLDPSYLLCWIGQALIAETVGSYDTMDLFRHTTELSMHTEGAIGYAYWVCTTLQDKSNRETELYKYNILQMNAVPAAQGVLCKYVERIQNYAPAFTMLGYLNEHLQLRREAAEAYQRATSLLHSTEDQHTYSVTVRNWGRLLCSIGEYDKAVEAFKSTPLEELEDIVGLALALFMKELYKESSKAYERALTVVKSEQDKAHVLTALAITEYKQGQMDTAKSLLFKCSILKEPTIESLQALCALGLAMQDATLSKAALNEFLKHTKHKNDYHRCLLTSAICALQGRSVAVQRQAAKAVHSNPADPALWSLLSRVVAQYTQRNAKGGAVAGAVAHVLDANHGKKALLYTAINQLAMGSGTAEDEKNISLKTIQKAAFLSPDDPAVWAGLMAACHADDKLALVNNIQPKRVDLHLALLSAVSASLKDKDILQNYNQSLEKWSLSQAVTGLIDTGRISEAESLCTKNLKSNPDQPAVILLLRQVQCKSLLESQKPLPDAVLEELQKTVMSNSTSVPAWQWLAQVYQSQGMMGAAEMCYRKSLQVASQQGNWSGKLSSLLKLALLALEVCMANVSSDHWSSLLQEATSEALKVCFCPLAVFLQALLQFNRKMGARETRRLLEKVVYQPGYPNSIVSTARWYLLRHLYAKNDQELIDVLVKNAEAHSDKRTLELNEKLSSQ", "length": 1563 }, "evidence": [ { "id": "E1C576", "url": "https://omabrowser.org/oma/group/E1C576/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P17883-1", "protein_name": "Superkiller protein 3", "gene_name": "SKI3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDIKQLLKEAKQELTNRDYEETIEISEKVLKLDPDNYFAHIFLGKALSSLPASNNVSSNRNLERATNHYVSAAKLVPDNLLAWKGLFLLFRTTEVVPDILSYDEYFDLCGQYADALLKQEQSQVELINDIKLLKKTHPDCQKAFYQHLKPGSLMAETIGRHLSTPQDALLNLIKILSNIETTEIGKTLSQNRLKLKASDPDYQIKLNSFSWEIIKNSEIDQLYNQLVNILADDQKRSEIENQWLEYRIKVLKSMPLDVKKDFFTKVKEMVEDMVLVNHQSLLAWQKYFEWTDYEDLDNMDAPLIIKYFKKFPKDPLAMILYSWLSSKLSKYDIKSLESANKPPEGHKKTEKETDIKDVDETNEDEVKDRVEDEVKDRVEDEVKDQDEEAKEDEEEDLDDIEIGLLEEEVVTVLTENIVKCKNNILAHRILCQYYLLTKEYEAALPYIKNGISLIAYNIKDLGVHLPLTKREFSLDLATVYTYVDAPKDHNAALKLYDNILSGDFSNIQAKMGKGIIFIERKNWKDAMTLLTQVHEQSPNNLEVLSELSWSKAHMGYMDEALAGLDTVIKGIKGMDLRSIDFRALNLWRQAKVYIMKHASINDAKQENVKCAFKLLIQSIKILDTFAPGFSTLGDIYCHYYKDHLRAFKCYFKAFDLDAGDYTAAKYITETYASKPNWQAASSIASRLIKGEKAKAELRSNNWPFRVVGIAHLEKQEESDSIEWFQSALRVDPNDVESWVGLGQAYHACGRIEASIKVFDKAIQLRPSHTFAQYFKAISLCDVGEYLESLDILEKVCQEAATEESFQIGLVEVLMRCSLDLYSQGFLLKSVSIAKDTIERIKIIISELKCENQQVWIYLSQVLRLFIWIESKVDTLPVESLVSIFENSQFSGSEEIDSVDNIKIDTLLDSTTDDNVSIACKFLILASKYSVSDQKFTDIAGTVRASYWYNIGISELTAFITLKEPQYRDAAIFAFKKSIQLQSNTSETWIGLGIATMDINFRVSQHCFIKATALEPKATNTWFNLAMLGLKKKDTEFAQQVLNKLQSLAPQDSSPWLGMALILEEQGDIIGSSKLFAHSFILSNGRSKAAQFMYAKNVLENHINNGDDERDIETVEKLTTASIALEQFFKKSPDSQFALQCALLTLERLHHYENANELANRLIGILEKKFEKTQDERELFNFAIIKGQFARIHLGLGNFELSIENADLSQGIISESSDEKSMKTKISNHICLGLSYFFLNDFDQTLNQFQELLSISKDSKHLVVLIAKVLYDVGESDTKEIALQELTEYIATSGADLLVTLTIAAMSILDDKREDLSIILEELKALPLSKQIIDKHKDAPYLIEEITKRLYRNDTGKQVWQRSAYFFPNNLKVWERLDKNIQRRIASNGQNKVTAEEMSKLYCESKNLRSIQRGMFLCPWNVTAVKALNECF", "length": 1432 }, "evidence": [ { "id": "E1C576", "url": "https://omabrowser.org/oma/group/E1C576/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6PGP7-1", "protein_name": "Superkiller complex protein 3", "gene_name": "SKIC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLYYQEKKHLEVARTWHKLIKTRQEQGAENEELHQLWRKLTQFLAESTEDQNNETQQLLFTAFENALGLSDKIPSEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPLEVLCLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLKESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGRCYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSIVESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATLSKAALNELLKHIKHKDSNYQRCLLTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLLSRVVAQYAQRNAKGGVVAGNVAHILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQKAALLSPGDPAIWAGLMAACHADDKLALVNNTQPKRIDLYLALLSAVSASIKDEKFFENYNQSLEKWSLSQAVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKPLPDAVLEELQKTVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKLSSLLRLALLALKVCMANISNDHWPSLVQEATTEALKLCFCPLAVLLQALLQFKRKMGARETRRLLERVVYQPGYPKSIASTARWYLLRHLYAKDDYELIDVLVNNAKTHGDTRALELNQRLSSQ", "length": 1564 }, "evidence": [ { "id": "E1C576", "url": "https://omabrowser.org/oma/group/E1C576/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Ski complex", "id": "GO:0055087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055087", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" }, { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay", "id": "GO:0070478", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070478", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" }, { "name": "nuclear-transcribed mRNA catabolic process", "id": "GO:0000956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000956", "evidence": [ { "database": "UniProtKB", "id": "E1C576", "url": "https://www.uniprot.org/uniprotkb/E1C576" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1287, "end_pos": 1289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1323, "end_pos": 1325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1454, "end_pos": 1456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1287, "end_pos": 1289 }, { "start_pos": 1323, "end_pos": 1325 }, { "start_pos": 1454, "end_pos": 1456 }, { "start_pos": 176, "end_pos": 178 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3Q4-1", "uniprot_ac": "E1C3Q4", "uniprot_id": "E1C3Q4_CHICK", "mass": { "chemical_mass": 59864.0, "monoisotopic_mass": 59864.0 }, "refseq": { "ac": "NP_001383786", "name": "cleavage stimulation factor subunit 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383786" }, "gene_names": [ { "name": "CSTF1", "type": "recommended", "evidence": [ { "id": "E1C3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4" } ] }, { "name": "CSTF1", "type": "synonym", "evidence": [ { "id": "NP_001383786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383786" } ] } ], "protein_names": [ { "name": "Cleavage stimulation factor subunit 1", "type": "recommended", "evidence": [ { "id": "E1C3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4/entry#names_and_taxonomy" } ] }, { "name": "Cleavage stimulation factor 50 kDa subunit", "type": "synonym", "evidence": [ { "id": "E1C3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4/entry#names_and_taxonomy" } ] }, { "name": "cleavage stimulation factor subunit 1", "type": "synonym", "evidence": [ { "id": "NP_001383786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383786" } ] }, { "name": "cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa", "type": "synonym", "evidence": [ { "id": "NP_001383786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383786" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.233943.1, SRR13267659.91792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN08016663 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000328.1. On or before Oct 26, 2021 this sequence version replaced XP_024998199.2, XP_040544496.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001383786", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383786" } ] }, { "annotation": "One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR2#function" }, { "database": "UniProtKB", "id": "ARBA00058408", "url": "https://www.uniprot.org/uniprotkb/ARBA00058408#function" }, { "database": "UniProtKB", "id": "A0A8V0YJ46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ46#function" }, { "database": "UniProtKB", "id": "A0A8V0YL22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL22#function" }, { "database": "UniProtKB", "id": "E1C3Q4", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3Q4", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CSTF1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4", "locus": { "chromosome": "20", "start_pos": 12353618, "end_pos": 12362595, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013220", "url": "https://www.ensembl.org/id/ENSGALG00010013220" } ] } } ], "crossref": [ { "id": "E1C3Q4", "url": "https://alphafold.ebi.ac.uk/entry/E1C3Q4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007757", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419331", "url": "https://www.ncbi.nlm.nih.gov/gene/419331", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HTEDYVM", "url": "https://omabrowser.org/oma/group/HTEDYVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCR2", "url": "https://www.orthodb.org/?gene=A0A8V0YCR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YJ46", "url": "https://www.orthodb.org/?gene=A0A8V0YJ46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YL22", "url": "https://www.orthodb.org/?gene=A0A8V0YL22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3Q4", "url": "https://www.orthodb.org/?gene=E1C3Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44133:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44133:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-77595", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77595", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001383786", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YCR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YJ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJ46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YL22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Q4", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Q4-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRRVAAACDRRQLPRGMGSMASPLLDPRPLRLPFLEADSRLQSICGRSMQQPSRRSILRSRPPPPPPPLPPPPIDALRAPVAILGGERGRQKEGSAPPRHSLLTMYRTKVSLKDRQQLYKLIISQLLYDGYINIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDSAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHIDAICSVNYNASANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVKYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNSIVRCIVHSPTNPGFMTCSDDYRARFWYRRSTTD", "length": 537, "header": "tr|E1C3Q4-1|E1C3Q4_CHICK Isoform 1 of Cleavage stimulation factor subunit 1 OS=Gallus gallus OX=9031 GN=CSTF1 PE=1 SV=4 CANONICAL=E1C3Q4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YCR2-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4/entry#A0A8V0YCR2-1", "sequence": { "sequence": "MSGRRVAAACDRRQLPRGMGSMASPLLDPRPLRLPFLEADAPPRHSLLTMYRTKVSLKDRQQLYKLIISQLLYDGYINIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDSAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHIDAICSVNYNASANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVKYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNSIVRCIVHSPTNPGFMTCSDDYRARFWYRRSTTD", "length": 480, "header": "tr|A0A8V0YCR2-1|E1C3Q4_CHICK Computationally mapped isoform of Cleavage stimulation factor subunit 1 OS=Gallus gallus OX=9031 GN=CSTF1 PE=1 SV=1 CANONICAL=E1C3Q4-1" }, "locus": { "chromosome": "20", "start_pos": 12361825, "end_pos": 12354941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031754.1", "url": "https://www.ensembl.org/id/ENSGALT00010031754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018586.1", "url": "https://www.ensembl.org/id/ENSGALP00010018586.1" } ] } }, { "isoform_ac": "A0A8V0YJ46-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4/entry#A0A8V0YJ46-1", "sequence": { "sequence": "MSGRRVAAACDRRQLPRGMGSMASPLLDPRPLRPPPPIDALRAPVAILGGERGRQKEGSAPPRHSLLTMYRTKVSLKDRQQLYKLIISQLLYDGYINIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDSAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHIDAICSVNYNASANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVKYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNSIVRCIVHSPTNPGFMTCSDDYRARFWYRRSTTD", "length": 499, "header": "tr|A0A8V0YJ46-1|E1C3Q4_CHICK Computationally mapped isoform of Cleavage stimulation factor subunit 1 OS=Gallus gallus OX=9031 GN=CSTF1 PE=1 SV=1 CANONICAL=E1C3Q4-1" }, "locus": { "chromosome": "20", "start_pos": 12361825, "end_pos": 12354941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031749.1", "url": "https://www.ensembl.org/id/ENSGALT00010031749.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018583.1", "url": "https://www.ensembl.org/id/ENSGALP00010018583.1" } ] } }, { "isoform_ac": "A0A8V0YL22-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4/entry#A0A8V0YL22-1", "sequence": { "sequence": "MQQPSQKEGSAPPRHSLLTMYRTKVSLKDRQQLYKLIISQLLYDGYINIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDSAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHIDAICSVNYNASANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVKYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNSIVRCIVHSPTNPGFMTCSDDYRARFWYRRSTTD", "length": 450, "header": "tr|A0A8V0YL22-1|E1C3Q4_CHICK Computationally mapped isoform of Cleavage stimulation factor subunit 1 OS=Gallus gallus OX=9031 GN=CSTF1 PE=1 SV=1 CANONICAL=E1C3Q4-1" }, "locus": { "chromosome": "20", "start_pos": 12361086, "end_pos": 12354941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031742.1", "url": "https://www.ensembl.org/id/ENSGALT00010031742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018579.1", "url": "https://www.ensembl.org/id/ENSGALP00010018579.1" } ] } }, { "isoform_ac": "E1C3Q4-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4/entry#E1C3Q4-1", "sequence": { "sequence": "MSGRRVAAACDRRQLPRGMGSMASPLLDPRPLRLPFLEADSRLQSICGRSMQQPSRRSILRSRPPPPPPPLPPPPIDALRAPVAILGGERGRQKEGSAPPRHSLLTMYRTKVSLKDRQQLYKLIISQLLYDGYINIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDSAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHIDAICSVNYNASANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVKYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNSIVRCIVHSPTNPGFMTCSDDYRARFWYRRSTTD", "length": 537, "header": "tr|E1C3Q4-1|E1C3Q4_CHICK Isoform 1 of Cleavage stimulation factor subunit 1 OS=Gallus gallus OX=9031 GN=CSTF1 PE=1 SV=4 CANONICAL=E1C3Q4-1" }, "locus": { "chromosome": "20", "start_pos": 12361825, "end_pos": 12354941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031746.1", "url": "https://www.ensembl.org/id/ENSGALT00010031746.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018581.1", "url": "https://www.ensembl.org/id/ENSGALP00010018581.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-77595", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77595", "resource": "Reactome", "description": "Processing of Intronless Pre-mRNAs" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QFK9-1", "protein_name": "Cleavage stimulation factor subunit 1", "gene_name": "cstf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFRPKPTLKDRQHLYKLIISQLLYDGYTIIANSLISEVKPQNVVSPSEQLMQLAKIGMENDDSAVQYAIGRSDTVAPGVGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPLEVMMNETAQQNMENHPVIRTLYDHVDEVTCLSFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKHVQEAEMLRSISFHPSGDFLLVGTQHPTLRLYDVNTFQCFVSCNPLDQHTDTICGVCYNPSANSYVTCSKDGSIKLWDGVSNRCVTTFDKAHEGAEVCSAVFSKNSKYILSTGKDSVAKLWEISTGRTLVKYTGAGLSGRQTHRTQGVFNHTEDYVLLPDERTISLCCWDSRTAERKNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRTTTD", "length": 431 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HBL5-1", "protein_name": "Cleavage stimulation factor subunit 1", "gene_name": "Cstf1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVSYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "length": 431 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q05048-1", "protein_name": "Cleavage stimulation factor subunit 1", "gene_name": "CSTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYVLLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "length": 431 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54XS9-1", "protein_name": "Cleavage stimulation factor 50 kDa subunit", "gene_name": "cstf1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKEEQRDLYSLIINQLVHDGYLNEATKISESTMIPCPIKGEASNKLFSLYQSTISGSGGLGMHSGINRVNSNMDIDDDSSTIGSSGGKNSIEDIINMKECLDFDDPIQQQQLITGSSSTSTTATTTTTSSSSSSSTSDGTTNTTGIITEKVQQQQLQPNFITKFITTHKNACRCAKFSWDGKYVATGSSDTSIKLLDVNKMRNYNQTKNETTEDSAPSRPVIRTFYDHTMPINDLDFHPSAPILSSASKDGTIRFYDYKSSLKRSFKYIQDTHGIRSINFHPCGDLILAGTDHQMIRLYNVNTFQSFTARKINEHHHGPINQVRFSLDGNIFASCSKDNTIKIWDSNNFSLISTLNSPHGGKEPTTVQISRNQKYLLSCGRDSMIKLWEITSGRLIYSINTGVNQSGGQNKNRISATFNYTEDYIITNDEQPSVAVVYNSRTKEQVQKLTGHNNTVRYIAASPVENALMTCSLDHRGRFWTDDTLSLSSNPINNNNNIVNKLDVDI", "length": 506 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BJQ6-1", "protein_name": "Cleavage stimulation factor subunit 1", "gene_name": "Cstf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "length": 431 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8L4J2-1", "protein_name": "Cleavage stimulation factor subunit 50", "gene_name": "CSTF50", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGNSGDLEQALQDGNIFRQLNALIVAHLRHHNLSQVASAVASATMTPLNIEVPPNRLLELVAKGLAAENNGTLRGVSSSVLLPSSYGSITTPRTASIDFSVNHAKGSSKTIPKHESKTLSEHKSVVRCARFSPDGMFFATGGADTSIKLFEVPKVKQMISGDTQARPLIRTFYDHAEPINDLDFHPRSTILISSAKDNCIKFFDFSKTTAKRAFKVFQDTHNVRSISFHPSGEFLLAGTDHPIPHLYDVNTYQCFLPSNFPDSGVSGAINQVRYSSTGSIYITASKDGAIRLFDGVSAKCVRSIGNAHGKSEVTSAVFTKDQRFVLSSGKDSTVKLWEIGSGRMVKEYLGAKRVKLRSQAIFNDTEEFVISIDEASNEVVTWDARTADKVAKWPSNHNGAPRWIEHSPVESVFVTCGIDRSIRFWKESV", "length": 429 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q99LC2-1", "protein_name": "Cleavage stimulation factor subunit 1", "gene_name": "Cstf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD", "length": 431 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V9V0-1", "protein_name": "Cleavage stimulation factor subunit 1", "gene_name": "CstF50", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRDEILDPSNLVKNREILYRLMISQLMYDGLEKFAMELSMLVKADQCAPSERLLHVMIAGMQTLSDKDKTNSDDVLPGIDLEFEPEASALAPEPHSYETAYVTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERMLAKSAPEDIEPGREQQGHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAKPSVKKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAIPSQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAHGGAAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAGTTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLTLNSLGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRANNQ", "length": 424 }, "evidence": [ { "id": "E1C3Q4", "url": "https://omabrowser.org/oma/group/E1C3Q4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q4", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4" } ], "pmid": "" }, { "name": "regulation of mRNA 3'-end processing", "id": "GO:0031440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031440", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q4", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mRNA cleavage stimulating factor complex", "id": "GO:0005848", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005848", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q4", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q4", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C3Q4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 537, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C3Q4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C3Q4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q4" }, { "id": "PF16699", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16699" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cleavage stimulation factor subunit 1 dimerisation", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 166, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 468, "end_pos": 470 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C6L7-1", "uniprot_ac": "E1C6L7", "uniprot_id": "E1C6L7_CHICK", "mass": { "chemical_mass": 32329.0, "monoisotopic_mass": 32329.0 }, "refseq": { "ac": "XP_015149386", "name": "delta-sarcoglycan isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149386" }, "gene_names": [ { "name": "SGCD", "type": "recommended", "evidence": [ { "id": "E1C6L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ] }, { "name": "SGCD", "type": "synonym", "evidence": [ { "id": "XP_015149386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149386" } ] } ], "protein_names": [ { "name": "Sarcoglycan delta", "type": "synonym", "evidence": [ { "id": "E1C6L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#names_and_taxonomy" } ] }, { "name": "delta-sarcoglycan isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149386" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149386" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SGCD", "url": "https://www.uniprot.org/uniprotkb/E1C6L7", "locus": { "chromosome": "13", "start_pos": 11076976, "end_pos": 11546769, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015483", "url": "https://www.ensembl.org/id/ENSGALG00010015483" } ] } } ], "crossref": [ { "id": "E1C6L7", "url": "https://alphafold.ebi.ac.uk/entry/E1C6L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003886", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003886", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416251", "url": "https://www.ncbi.nlm.nih.gov/gene/416251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416251", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLYCFIC", "url": "https://omabrowser.org/oma/group/CLYCFIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKU9", "url": "https://www.orthodb.org/?gene=A0A8V0YKU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKY0", "url": "https://www.orthodb.org/?gene=A0A8V0YKY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSB6", "url": "https://www.orthodb.org/?gene=A0A8V0YSB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSJ8", "url": "https://www.orthodb.org/?gene=A0A8V0YSJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YU14", "url": "https://www.orthodb.org/?gene=A0A8V0YU14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ13", "url": "https://www.orthodb.org/?gene=A0A8V0YZ13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6L7", "url": "https://www.orthodb.org/?gene=E1C6L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12939:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12939:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149386", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149386", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6L7-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGKMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEITLNSAKIKLPNLPQGSSSSAGSRQKIYELCVCPNGRLFLSQAGASSTCQINTSVCL", "length": 292, "header": "tr|E1C6L7-1|E1C6L7_CHICK Isoform 1 of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=5 CANONICAL=E1C6L7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKU9-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#A0A8V0YKU9-1", "sequence": { "sequence": "MSTGQASCSSGSSAASSSDPPAQLQAVNSHRQRGKSRGVPSRSRRMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEITLNSAKIKLPNLPQGSSSSAGSRQKIYELCVCPNGRLFLSQAGASSTCQINTSVCL", "length": 333, "header": "tr|A0A8V0YKU9-1|E1C6L7_CHICK Computationally mapped isoform of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=1 CANONICAL=E1C6L7-1" }, "locus": { "chromosome": "13", "start_pos": 11256090, "end_pos": 11127677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037166.1", "url": "https://www.ensembl.org/id/ENSGALT00010037166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021575.1", "url": "https://www.ensembl.org/id/ENSGALP00010021575.1" } ] } }, { "isoform_ac": "A0A8V0YKY0-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#A0A8V0YKY0-1", "sequence": { "sequence": "MLGKMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEEKHRFITKMHVRAYSNRKPLIPFTERNGNNLEFFRCVQKVRLPRKRNMRR", "length": 285, "header": "tr|A0A8V0YKY0-1|E1C6L7_CHICK Computationally mapped isoform of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=1 CANONICAL=E1C6L7-1" }, "locus": { "chromosome": "13", "start_pos": 11317961, "end_pos": 11122907, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037218.1", "url": "https://www.ensembl.org/id/ENSGALT00010037218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021605.1", "url": "https://www.ensembl.org/id/ENSGALP00010021605.1" } ] } }, { "isoform_ac": "A0A8V0YSB6-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#A0A8V0YSB6-1", "sequence": { "sequence": "MLGKMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEVSNTPSLTLAQNGRTGTLHSKSPKCAEYYCSPMSS", "length": 270, "header": "tr|A0A8V0YSB6-1|E1C6L7_CHICK Computationally mapped isoform of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=1 CANONICAL=E1C6L7-1" }, "locus": { "chromosome": "13", "start_pos": 11317961, "end_pos": 11080204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037222.1", "url": "https://www.ensembl.org/id/ENSGALT00010037222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021607.1", "url": "https://www.ensembl.org/id/ENSGALP00010021607.1" } ] } }, { "isoform_ac": "A0A8V0YSJ8-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#A0A8V0YSJ8-1", "sequence": { "sequence": "MLGKMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEAASSYSLTHRNRRTRILYGSKVQRRPQNSPSSTAS", "length": 270, "header": "tr|A0A8V0YSJ8-1|E1C6L7_CHICK Computationally mapped isoform of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=1 CANONICAL=E1C6L7-1" }, "locus": { "chromosome": "13", "start_pos": 11317961, "end_pos": 11076989, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037229.1", "url": "https://www.ensembl.org/id/ENSGALT00010037229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021610.1", "url": "https://www.ensembl.org/id/ENSGALP00010021610.1" } ] } }, { "isoform_ac": "A0A8V0YU14-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#A0A8V0YU14-1", "sequence": { "sequence": "MLKICFLFAQFLEETEAKMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEITLNSAKIKLPNLPQGSSSSAGSRQKIYELCVCPNGRLFLSQAGASSTCQINTSVCL", "length": 306, "header": "tr|A0A8V0YU14-1|E1C6L7_CHICK Computationally mapped isoform of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=1 CANONICAL=E1C6L7-1" }, "locus": { "chromosome": "13", "start_pos": 11256662, "end_pos": 11127677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037191.1", "url": "https://www.ensembl.org/id/ENSGALT00010037191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021588.1", "url": "https://www.ensembl.org/id/ENSGALP00010021588.1" } ] } }, { "isoform_ac": "A0A8V0YZ13-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#A0A8V0YZ13-1", "sequence": { "sequence": "MQLTCAEPCLSLPMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEITLNSAKIKLPNLPQGSSSSAGSRQKIYELCVCPNGRLFLSQAGASSTCQINTSVCL", "length": 301, "header": "tr|A0A8V0YZ13-1|E1C6L7_CHICK Computationally mapped isoform of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=1 CANONICAL=E1C6L7-1" }, "locus": { "chromosome": "13", "start_pos": 11288358, "end_pos": 11127677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037203.1", "url": "https://www.ensembl.org/id/ENSGALT00010037203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021596.1", "url": "https://www.ensembl.org/id/ENSGALP00010021596.1" } ] } }, { "isoform_ac": "E1C6L7-1", "url": "https://www.uniprot.org/uniprotkb/E1C6L7/entry#E1C6L7-1", "sequence": { "sequence": "MLGKMPQEQYAHRSTMQTSEGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITDKGLKLEGDSEFLKPLYAKEIRSRPGNPLYFQSARNVTVNILNEKTKVLTRLVTGPQAVEAHSQKFEVKTLSGKLLFSADDNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRALVMEAPKGIEINAEAGSLKATCRTELRLESKDGEITLNSAKIKLPNLPQGSSSSAGSRQKIYELCVCPNGRLFLSQAGASSTCQINTSVCL", "length": 292, "header": "tr|E1C6L7-1|E1C6L7_CHICK Isoform 1 of Sarcoglycan delta OS=Gallus gallus OX=9031 GN=SGCD PE=1 SV=5 CANONICAL=E1C6L7-1" }, "locus": { "chromosome": "13", "start_pos": 11317961, "end_pos": 11127677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037211.1", "url": "https://www.ensembl.org/id/ENSGALT00010037211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021600.1", "url": "https://www.ensembl.org/id/ENSGALP00010021600.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416251", "resource": "KEGG Pathway" }, { "id": "R-GGA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3AU43-1", "protein_name": "Delta-sarcoglycan isoform X4", "gene_name": "sgcd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTQEQCPHRNNVQSTEKPQVYKVGIYGWRKRCLYFFVLLLMILIVVNLALTIWILKVMNFTIDGMGHLRITERGLKLEGDSEFLQPLYAKEIQSRPGSPLFLQSSKNVSVNILNEKKQLVSQLVAGSHGVHARGKMLEVKSSSGKLLFSADDHEVVVGAERLRVMGAEGAVFSNSVETPHVRAEPFKELRLESPTRSLYMEAPKGVKIEADAGDFQATCRSDLRLESKDGEISLDASKIKLPRLPEGKASTSGPRQTVFEVCVCPNGKLFLSQAGTGSTCQMSSNLCL", "length": 288 }, "evidence": [ { "id": "E1C6L7", "url": "https://omabrowser.org/oma/group/E1C6L7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LRK7-1", "protein_name": "Sarcoglycan, delta", "gene_name": "Sgcd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATAISPSDTFSCFCSLLLACLAKCLFILMPQEQYSHHRSTMPSSEGPHIYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIKSRPGNALYFKSARNVTVNILNDQTKVLTQLVTGPKAVEAYGKRFEVKTVSGKLLFSADDSEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEATCRSELRLESKDGEIKLDAAKIKLPRLPRGSYTPTGTRQKVFEVCVCANGRLFLSQAGTGSTCQINTSVCL", "length": 318 }, "evidence": [ { "id": "E1C6L7", "url": "https://omabrowser.org/oma/group/E1C6L7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P82347-1", "protein_name": "Delta-sarcoglycan", "gene_name": "Sgcd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQEQYSHHRSTMPSSEGPHIYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIKSRPGNALYFKSARNVTVNILNDQTKVLTQLVTGPKAVEAYGKRFEVKTVSGKLLFSADDSEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEAICRSELRLESKDGEIKLDAAKIKLPRLPRGSYTPTGTRQKVFEVCVCANGRLFLSQAGTGSTCQINTSVCL", "length": 289 }, "evidence": [ { "id": "E1C6L7", "url": "https://omabrowser.org/oma/group/E1C6L7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92629-1", "protein_name": "Delta-sarcoglycan", "gene_name": "SGCD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQEQYTHHRSTMPGSVGPQVYKVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALYFKSARNVTVNILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFKELRLESPTRSLVMEAPKGVEINAEAGNMEATCRTELRLESKDGEIKLDAAKIRLPRLPHGSYTPTGTRQKVFEICVCANGRLFLSQAGAGSTCQINTSVCL", "length": 289 }, "evidence": [ { "id": "E1C6L7", "url": "https://omabrowser.org/oma/group/E1C6L7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ], "pmid": "" }, { "name": "sarcoglycan complex", "id": "GO:0016012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016012", "evidence": [ { "database": "UniProtKB", "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ], "pmid": "" }, { "name": "cardiac muscle tissue development", "id": "GO:0048738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048738", "evidence": [ { "database": "UniProtKB", "id": "E1C6L7", "url": "https://www.uniprot.org/uniprotkb/E1C6L7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NAH2-1", "uniprot_ac": "F1NAH2", "uniprot_id": "F1NAH2_CHICK", "mass": { "chemical_mass": 29631.0, "monoisotopic_mass": 29631.0 }, "refseq": { "ac": "XP_001232254", "name": "protein FAM78B isoform X2", 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Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232254" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NAH2", "url": "https://www.uniprot.org/uniprotkb/F1NAH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM78B", "url": "https://www.uniprot.org/uniprotkb/F1NAH2", "locus": { "chromosome": "8", "start_pos": 4313484, "end_pos": 4306015, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013511", "url": "https://www.ensembl.org/id/ENSGALG00010013511" } ] } } ], "crossref": [ { "id": "F1NAH2", "url": "https://alphafold.ebi.ac.uk/entry/F1NAH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003035", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003035", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "769830", "url": "https://www.ncbi.nlm.nih.gov/gene/769830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769830", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IDHCPTI", "url": "https://omabrowser.org/oma/group/IDHCPTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YKY9", "url": "https://www.orthodb.org/?gene=A0A8V0YKY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NAH2", "url": "https://www.orthodb.org/?gene=F1NAH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31655:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31655:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001232254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YKY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAH2", "url": "https://www.uniprot.org/uniprotkb/F1NAH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAH2-1", "url": "https://www.uniprot.org/uniprotkb/F1NAH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCLQSVACKARVRREHIVVSDVSATIEPAATAIEESSPVVLRYRTPYFRASARVLMPPIARRHTWVVGWIQACNHMEFYNTYSDLGVSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSNSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPMQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGQPIVVIPPK", "length": 261, "header": "tr|F1NAH2-1|F1NAH2_CHICK Isoform 1 of Family with sequence similarity 78 member B OS=Gallus gallus OX=9031 GN=FAM78B PE=4 SV=2 CANONICAL=F1NAH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YKY9-1", "url": "https://www.uniprot.org/uniprotkb/F1NAH2/entry#A0A8V0YKY9-1", "sequence": { "sequence": "MRDSGAALSGNEDFQPQELWALDIPSSTACAVPSAPGVSRALCRSAGTGVASFHQFPALEKHPLSSTPCWKTCCRYQSQPACISKGGSRWRLPWQSSAWKSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSNSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPMQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGQPIVVIPPK", "length": 273, "header": "tr|A0A8V0YKY9-1|F1NAH2_CHICK Computationally mapped isoform of Family with sequence similarity 78 member B OS=Gallus gallus OX=9031 GN=FAM78B PE=4 SV=1 CANONICAL=F1NAH2-1" }, "locus": { "chromosome": "8", "start_pos": 4309905, "end_pos": 4307403, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032505.1", "url": "https://www.ensembl.org/id/ENSGALT00010032505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019247.1", "url": "https://www.ensembl.org/id/ENSGALP00010019247.1" } ] } }, { "isoform_ac": "F1NAH2-1", "url": "https://www.uniprot.org/uniprotkb/F1NAH2/entry#F1NAH2-1", "sequence": { "sequence": "MGCLQSVACKARVRREHIVVSDVSATIEPAATAIEESSPVVLRYRTPYFRASARVLMPPIARRHTWVVGWIQACNHMEFYNTYSDLGVSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSNSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPMQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGQPIVVIPPK", "length": 261, "header": "tr|F1NAH2-1|F1NAH2_CHICK Isoform 1 of Family with sequence similarity 78 member B OS=Gallus gallus OX=9031 GN=FAM78B PE=4 SV=2 CANONICAL=F1NAH2-1" }, "locus": { "chromosome": "8", "start_pos": 4309905, "end_pos": 4306140, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032508.1", "url": "https://www.ensembl.org/id/ENSGALT00010032508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019249.1", "url": "https://www.ensembl.org/id/ENSGALP00010019249.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769830", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGD7-1", "protein_name": "Family with sequence similarity 78, member B", "gene_name": "Fam78b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "F1NAH2", "url": "https://omabrowser.org/oma/group/F1NAH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0V2R6-1", "protein_name": "Uncharacterized protein LOC796762", "gene_name": "fam78bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCLQSVACKPRIKRENIVVYDVSATIDHCPTVIEENSPIVLRYKTPYFKASARIVMPPIPRNETWVVGWIQACTQMEFYNTYGDLGMSSWELPELREGLVKAISDSDGLSYPWYGNTTETVTLSGPTSKPSRFTVSMNDNFYPSVTWAVPVSESNVPLLTRIKRDQSFTTWLVALNVTTQEKILLQTVKWRMKVDIAVDPSKPLSSRARLIGRVHQDQPKVLTHMEQIPPNALGKPNANDAQVLMWRPKRGPPLVVIPSK", "length": 261 }, "evidence": [ { "id": "F1NAH2", "url": "https://omabrowser.org/oma/group/F1NAH2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S245-1", "protein_name": "Family with sequence similarity 78 member B", "gene_name": "FAM78B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "F1NAH2", "url": "https://omabrowser.org/oma/group/F1NAH2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5VT40-1", "protein_name": "Protein FAM78B", "gene_name": "FAM78B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "F1NAH2", "url": "https://omabrowser.org/oma/group/F1NAH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 177, "end_pos": 179 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NQ45-1", "uniprot_ac": "F1NQ45", "uniprot_id": "F1NQ45_CHICK", "mass": { "chemical_mass": 65698.0, "monoisotopic_mass": 65698.0 }, "refseq": { "ac": "NP_001006407", "name": "pre-mRNA-processing factor 17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006407" }, "gene_names": [ { "name": "CDC40", "type": "recommended", "evidence": [ { "id": "F1NQ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ] }, { "name": "CDC40", "type": "synonym", "evidence": [ { "id": "NP_001006407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006407" } ] } ], "protein_names": [ { "name": "Pre-mRNA-processing factor 17", "type": "recommended", "evidence": [ { "id": "F1NQ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ45/entry#names_and_taxonomy" } ] }, { "name": "Cell division cycle 40 homolog", "type": "synonym", "evidence": [ { "id": "F1NQ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ45/entry#names_and_taxonomy" } ] }, { "name": "PRP17 homolog", "type": "synonym", "evidence": [ { "id": "F1NQ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQ45/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle 40 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006407" } ] }, { "name": "pre-mRNA-processing factor 17", "type": "synonym", "evidence": [ { "id": "NP_001006407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006407" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719631.1, SRR13267648.30509.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000065.1. On Oct 25, 2021 this sequence version replaced NP_001006407.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006407" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDC40", "url": "https://www.uniprot.org/uniprotkb/F1NQ45", "locus": { "chromosome": "3", "start_pos": 66318179, "end_pos": 66355655, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013976", "url": "https://www.ensembl.org/id/ENSGALG00010013976" } ] } } ], "crossref": [ { "id": "F1NQ45", "url": "https://alphafold.ebi.ac.uk/entry/F1NQ45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015061", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015061", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421760", "url": "https://www.ncbi.nlm.nih.gov/gene/421760", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421760", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421760", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TLWHPHE", "url": "https://omabrowser.org/oma/group/TLWHPHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMD0", "url": "https://www.orthodb.org/?gene=A0A8V0YMD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NQ45", "url": "https://www.orthodb.org/?gene=F1NQ45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43979:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43979:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NQ45-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAIAALASYGGSDSESDSEPEADAGPQRAVVLASRDAVLHLRPPPAAPPALPVDAAPEVAVKEDVETGVHLDPAIKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFVTYGYALDPSIDNPEVATKYIGSVEEAEKNQGLTVFETGQKKIEKRKKFKENDASNIDGFLGPWAKYVDEKEVAKPSEEEQKELDEITAKRQKRGKLEDDKPGEEKTILHVKEMYDYQGRSYLHVPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHMLLSCSMDCKIKLWEVYGDRRCLRTFIGHGKAVRDICFNNAGTRFLSAAYDRYIKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDADGKLNIWDWKTTKLYSRIKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 580, "header": "tr|F1NQ45-1|F1NQ45_CHICK Isoform 1 of Pre-mRNA-processing factor 17 OS=Gallus gallus OX=9031 GN=CDC40 PE=1 SV=1 CANONICAL=F1NQ45-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMD0-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ45/entry#A0A8V0YMD0-1", "sequence": { "sequence": "MRYPQLLQQEDVETGVHLDPAIKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFVTYGYALDPSIDNPEVATKYIGSVEEAEKNQGLTVFETGQKKIEKRKKFKENDASNIDGFLGPWAKYVDEKEVAKPSEEEQKELDEITAKRQKRGKLEDDKPGEEKTILHVKEMYDYQGRSYLHVPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHMLLSCSMDCKIKLWEVYGDRRCLRTFIGHGKAVRDICFNNAGTRFLSAAYDRYIKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDADGKLNIWDWKTTKLYSRIKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 525, "header": "tr|A0A8V0YMD0-1|F1NQ45_CHICK Computationally mapped isoform of Pre-mRNA-processing factor 17 OS=Gallus gallus OX=9031 GN=CDC40 PE=1 SV=1 CANONICAL=F1NQ45-1" }, "locus": { "chromosome": "3", "start_pos": 66353388, "end_pos": 66319049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033511.1", "url": "https://www.ensembl.org/id/ENSGALT00010033511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019763.1", "url": "https://www.ensembl.org/id/ENSGALP00010019763.1" } ] } }, { "isoform_ac": "F1NQ45-1", "url": "https://www.uniprot.org/uniprotkb/F1NQ45/entry#F1NQ45-1", "sequence": { "sequence": "MSAAIAALASYGGSDSESDSEPEADAGPQRAVVLASRDAVLHLRPPPAAPPALPVDAAPEVAVKEDVETGVHLDPAIKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFVTYGYALDPSIDNPEVATKYIGSVEEAEKNQGLTVFETGQKKIEKRKKFKENDASNIDGFLGPWAKYVDEKEVAKPSEEEQKELDEITAKRQKRGKLEDDKPGEEKTILHVKEMYDYQGRSYLHVPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHMLLSCSMDCKIKLWEVYGDRRCLRTFIGHGKAVRDICFNNAGTRFLSAAYDRYIKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDADGKLNIWDWKTTKLYSRIKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 580, "header": "tr|F1NQ45-1|F1NQ45_CHICK Isoform 1 of Pre-mRNA-processing factor 17 OS=Gallus gallus OX=9031 GN=CDC40 PE=1 SV=1 CANONICAL=F1NQ45-1" }, "locus": { "chromosome": "3", "start_pos": 66355160, "end_pos": 66319049, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033515.1", "url": "https://www.ensembl.org/id/ENSGALT00010033515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019764.1", "url": "https://www.ensembl.org/id/ENSGALP00010019764.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421760", "resource": "KEGG Pathway" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RSY9-1", "protein_name": "Pre-mRNA-processing factor 17", "gene_name": "CDC40", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAAIAALAASYGSGSGSESDSDSEGGRCSLPAADSLMHLTKSPSAKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSTKYIGSVEEAEKNQGLTVFETGQKKIEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 579 }, "evidence": [ { "id": "F1NQ45", "url": "https://omabrowser.org/oma/group/F1NQ45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GXM5-1", "protein_name": "Pre-mRNA-processing factor 17", "gene_name": "Cdc40", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSAAIAALAASYGSGSGSESDSDSEGSRCPLPAADSLMHLTKSPSAKPSLTVAVDSAPEVAVKEDLETGVHLDPAIKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEERPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSSVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVVTCGWDGLIKLWD", "length": 579 }, "evidence": [ { "id": "F1NQ45", "url": "https://omabrowser.org/oma/group/F1NQ45/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60508-1", "protein_name": "Pre-mRNA-processing factor 17", "gene_name": "CDC40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAAIAALAASYGSGSGSESDSDSESSRCPLPAADSLMHLTKSPSSKPSLAVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSTMPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 579 }, "evidence": [ { "id": "F1NQ45", "url": "https://omabrowser.org/oma/group/F1NQ45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DC48-1", "protein_name": "Pre-mRNA-processing factor 17", "gene_name": "Cdc40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAAIAALAASYGSGSGSESDSDSEGSRCPLPAADSLMHLTKSPSAKLSLTVAVDSAPEVAVKEDLETGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTFATYGYALDPSLDNHQVSAKYIGSVEEAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWAKYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVGVNLRSSVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD", "length": 579 }, "evidence": [ { "id": "F1NQ45", "url": "https://omabrowser.org/oma/group/F1NQ45/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VD52-1", "protein_name": "Pre-mRNA-processing factor 17", "gene_name": "CDC40", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLGLQSYASSSDEESDHADAATATTNSEPSAPIPDHLLPVDKTHSLSKSIAVCAAPTVVPLGASAVPRTLDPTLKEVTYNPRYEEMYAPVKGPEHPDLTMQQRAPRNTLAGYVEKAHINAFEFENQRRTFHTYGYALDPSVDDQADGQSFVGDLQSAYDDNGKTVFEPPKAKKLRKQEKNDNPEDIEGFLGPWGKFENEVSVAKPNEQERAELDELLSKRHKRGRIPEDKPLEEKSTLHIKDAYDYQGRSYLHAPHDLGVNLRSNAPPTKCFLPKAHIHTWSGHNKGISSIRWFPKTAHLLLSGSMDCRVKLWEVYGERRCIRTFSGHRQAIKDIAWNNRGTNFLSASYDRYIKLWDAETGDVVSRFTTRKMPFCVKFHPDNSKQHLFVAGTSDKKIICWDTRSGDIVQEYDRHLGSVSTITFVDDNRRFVTTSDDKSMRIWEWDIPVDMKYIADPTMHSMPAVTLAPNGKWMACQSLDNKIVIFSALNRFKMNRKKTFTGHMVSGYACQLDFSPDMSYLVSGDGDGKCYIWDWKTTKMYKKWQAHDGVCISALWHPHEASKVVTAGWDGQIKYWD", "length": 576 }, "evidence": [ { "id": "F1NQ45", "url": "https://omabrowser.org/oma/group/F1NQ45/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ], "pmid": "" }, { "name": "embryonic brain development", "id": "GO:1990403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990403", "evidence": [ { "database": "UniProtKB", "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "F1NQ45", "url": "https://www.uniprot.org/uniprotkb/F1NQ45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NQ45-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 580, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NQ45-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NQ45" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1N931-1", "uniprot_ac": "F1N931", "uniprot_id": "F1N931_CHICK", "mass": { "chemical_mass": 61540.0, "monoisotopic_mass": 61540.0 }, "refseq": { "ac": "XP_004937308", "name": "mesoderm induction early response protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937308" }, "gene_names": [ { "name": "MIER3", "type": "recommended", "evidence": [ { "id": "F1N931", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N931" } ] }, { "name": "MIER3", "type": "synonym", "evidence": [ { "id": "XP_004937308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937308" } ] } ], "protein_names": [ { "name": "MIER family member 3", "type": "synonym", "evidence": [ { "id": "F1N931", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N931/entry#names_and_taxonomy" } ] }, { "name": "mesoderm induction early response protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937308", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937308" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937308" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1N931", "url": "https://www.uniprot.org/uniprotkb/F1N931" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIER3", "url": "https://www.uniprot.org/uniprotkb/F1N931", "locus": {} } ], "crossref": [ { "id": "F1N931", "url": "https://alphafold.ebi.ac.uk/entry/F1N931", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014721", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014721", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427146", "url": "https://www.ncbi.nlm.nih.gov/gene/427146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427146", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427146", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMNICSE", "url": "https://omabrowser.org/oma/group/PMNICSE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YMQ4", "url": "https://www.orthodb.org/?gene=A0A8V0YMQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N931", "url": "https://www.orthodb.org/?gene=F1N931", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937308", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YMQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N931", "url": "https://www.uniprot.org/uniprotkb/F1N931", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N931-1", "url": "https://www.uniprot.org/uniprotkb/F1N931-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEASFGSSSPVGSLSSEDHDFDPSAEMLVHDYDDERTLEEEEMMEESKNFGSEIEDLEKEGNMPLEDLLAFYGYEPTIPVMAGSSADSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHEATDFFPRPLRSNTTCDGDKESDGEDIETDNGNSSEDLRKEIMVGSQYQAEIPPYLGRHSDNEKAYENEDHLLWKPDVISESKVKEYLFETSLRTGNEKLIGRIPEGLHTRDNEQALYELLKSSHNVKEAIERYCSNGKASQEEMAAWTEEECRSFEHALLIYGKDFHLIQKHKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDEAEALGGAVHSSALTSNSRTETIPDQQLSILNSITANDLTALTNSVATVCHTSDVNCLDDAFPPMDSLPRAPVNHVPVGTEELLNLPSNGESDCFNLFETGFYHSELNPMNMCSEETERPAKRLKMGIPESFMNDVSVNNLGVDFENHTHHITSAKMAVSVADFSSLSSNETNGFINTHTLHQHTALHSE", "length": 549, "header": "tr|F1N931-1|F1N931_CHICK Isoform 1 of MIER family member 3 OS=Gallus gallus OX=9031 GN=MIER3 PE=4 SV=3 CANONICAL=F1N931-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YMQ4-1", "url": "https://www.uniprot.org/uniprotkb/F1N931/entry#A0A8V0YMQ4-1", "sequence": { "sequence": "MAEAFLIVGSLSSEDHDFDPSAEMLVHDYDDERTLEEEEMMEESKNFGSEIEDLEKEGNMPLEDLLAFYGYEPTIPVMAGSSADSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHEATDFFPRPLRSNTTCDGDKESDGEDIETDNGNSSEDLRKEIMVGSQYQAEIPPYLGRHSDNEKAYENEDHLLWKPDVISESKVKEYLFETSLRTGNEKLIGRIPEGLHTRDNEQALYELLKSSHNVKEAIERYCSNGKASQEEMAAWTEEECRSFEHALLIYGKDFHLIQKHKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDEAEALGGAVHSSALTSNSRTETIPDQQLSILNSITANDLTALTNSVATVCHTSDVNCLDDAFPPMDSLPRAPVNHVPVGTEELLNLPSNGESDCFNLFETGFYHSELNPMNMCSEETERPAKRLKMGIPESFMNDVSVNNLGVDFENHTHHITSAKMAVSVADFSSLSSNETNGFINTHTLHQHTALHSE", "length": 545, "header": "tr|A0A8V0YMQ4-1|F1N931_CHICK Computationally mapped isoform of MIER family member 3 OS=Gallus gallus OX=9031 GN=MIER3 PE=4 SV=1 CANONICAL=F1N931-1" }, "locus": { "chromosome": "Z", "start_pos": 18041529, "end_pos": 18022405, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032462.1", "url": "https://www.ensembl.org/id/ENSGALT00010032462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019212.1", "url": "https://www.ensembl.org/id/ENSGALP00010019212.1" } ] } }, { "isoform_ac": "F1N931-1", "url": "https://www.uniprot.org/uniprotkb/F1N931/entry#F1N931-1", "sequence": { "sequence": "MAEASFGSSSPVGSLSSEDHDFDPSAEMLVHDYDDERTLEEEEMMEESKNFGSEIEDLEKEGNMPLEDLLAFYGYEPTIPVMAGSSADSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHEATDFFPRPLRSNTTCDGDKESDGEDIETDNGNSSEDLRKEIMVGSQYQAEIPPYLGRHSDNEKAYENEDHLLWKPDVISESKVKEYLFETSLRTGNEKLIGRIPEGLHTRDNEQALYELLKSSHNVKEAIERYCSNGKASQEEMAAWTEEECRSFEHALLIYGKDFHLIQKHKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDEAEALGGAVHSSALTSNSRTETIPDQQLSILNSITANDLTALTNSVATVCHTSDVNCLDDAFPPMDSLPRAPVNHVPVGTEELLNLPSNGESDCFNLFETGFYHSELNPMNMCSEETERPAKRLKMGIPESFMNDVSVNNLGVDFENHTHHITSAKMAVSVADFSSLSSNETNGFINTHTLHQHTALHSE", "length": 549, "header": "tr|F1N931-1|F1N931_CHICK Isoform 1 of MIER family member 3 OS=Gallus gallus OX=9031 GN=MIER3 PE=4 SV=3 CANONICAL=F1N931-1" }, "locus": { "chromosome": "Z", "start_pos": 18041529, "end_pos": 18022405, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032470.1", "url": "https://www.ensembl.org/id/ENSGALT00010032470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019218.1", "url": "https://www.ensembl.org/id/ENSGALP00010019218.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427146", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZE77-1", "protein_name": "MIER family member 3", "gene_name": "Mier3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASFGSSSPGIEPRKEPVYSRQALRHIAVCPALGYFKQMITIGSLSSEDHDFDPTAEMLVHDYDDERTLEEEELMGDGKNFSSEIEDLEKEGNMPLEDLLAFYGYESTIPTVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSDFFPRPLRSNTTCDGDKESEIEDVETDSGNSPEDLRKEIMIGLQYQAEIPPYLGEYSGDEKAYENEDQLLWRPDVVLESKVKEYLIETSLRTGNEKVLDRISSGTHTRDNEQALYELLKCNHNVTEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLYGKDFHLIQKNKVRSRTVAECVAFYYMWKKSERYDYFAQQTKFGKKRYNHHPGVTDYMDRLVDETESLGDTVSSSALTSNRPEPIPDQPLNILSSFTASDLTALTNSVATVCNPTDVSCLDDSFSPLGNAPRGQVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSASETNGFINAHTLHQHAALHSE", "length": 580 }, "evidence": [ { "id": "F1N931", "url": "https://omabrowser.org/oma/group/F1N931/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UHF3-1", "protein_name": "Mesoderm induction early response protein 3", "gene_name": "Mier3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEELMDDGKNFSSEIEDLEKEGNMPLEDLLAFYGYESTIPAVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSEFFPRPLRSNTTCDGDKESEIEDVETDSGNSPEDLRREIMIGLEYQAEIPPYLGEYNGDDEKAYENEDQLLWHPGVLLESKVKEYLVETSLRTGNEKVLDRISSGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLHGKDFHLIQKDKVRSRTVAECVAFYYMWKKSERYDYFAQQTKFGKKRYNHHPGVTDYMDRLVDETESLGGTVSSSALTCNRPEPVPDQPLNILSSFTASDLTALTNSVATVCNPTAVNCLDDSFPPLANTPRGHVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSANETNGFINAHSLHQHQHAALHSE", "length": 551 }, "evidence": [ { "id": "F1N931", "url": "https://omabrowser.org/oma/group/F1N931/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z3K6-1", "protein_name": "Mesoderm induction early response protein 3", "gene_name": "MIER3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEEMMDEGKNFSSEIEDLEKEGTMPLEDLLAFYGYEPTIPAVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSDFFPRPLRSNTACDGDKESEVEDVETDSGNSPEDLRKEIMIGLQYQAEIPPYLGEYDGNEKVYENEDQLLWCPDVVLESKVKEYLVETSLRTGSEKIMDRISAGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDETEALGGTVNASALTSNRPEPIPDQQLNILNSFTASDLTALTNSVATVCDPTDVNCLDDSFPPLGNTPRGQVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMNMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSANETNGFISAHALHQHAALHSE", "length": 550 }, "evidence": [ { "id": "F1N931", "url": "https://omabrowser.org/oma/group/F1N931/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1N931", "url": "https://www.uniprot.org/uniprotkb/F1N931" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1N931", "url": "https://www.uniprot.org/uniprotkb/F1N931" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1N931", "url": "https://www.uniprot.org/uniprotkb/F1N931" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "F1N931", "url": "https://www.uniprot.org/uniprotkb/F1N931" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": 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"start_pos": 1, "end_pos": 549, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1N931-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1N931" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 529, "end_pos": 531 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NKY1-1", "uniprot_ac": "F1NKY1", "uniprot_id": "F1NKY1_CHICK", "mass": { "chemical_mass": 42931.0, "monoisotopic_mass": 42931.0 }, "refseq": {}, "gene_names": [ { "name": "AMACR", "type": "recommended", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] } ], "protein_names": [ { "name": "Alpha-methylacyl-CoA racemase", "type": "recommended", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1/entry#names_and_taxonomy" } ] }, { "name": "2-methylacyl-CoA racemase", "type": "synonym", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1/entry#names_and_taxonomy" } ] }, { "name": "5.1.99.4", "type": "synonym", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs.", "evidence": [ { "database": "UniProtKB", "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1#function" }, { "database": "UniProtKB", "id": "ARBA00056478", "url": "https://www.uniprot.org/uniprotkb/ARBA00056478#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AMACR", "url": "https://www.uniprot.org/uniprotkb/F1NKY1", "locus": { "chromosome": "Z", "start_pos": 10902965, "end_pos": 10924098, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013203", "url": "https://www.ensembl.org/id/ENSGALG00010013203" } ] } } ], "crossref": [ { "id": "F1NKY1", "url": "https://alphafold.ebi.ac.uk/entry/F1NKY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003326", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003326", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQU5", "url": "https://www.orthodb.org/?gene=A0A8V0YQU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NKY1", "url": "https://www.orthodb.org/?gene=F1NKY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48228:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48228:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193368", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193368", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-193775", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193775", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389887", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389887", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12657", "url": "https://www.rhea-db.org/rhea/12657", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40455", "url": "https://www.rhea-db.org/rhea/40455", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46732", "url": "https://www.rhea-db.org/rhea/46732", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YQU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKY1-1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRRSAGGGRSMALSGLRVLELAGLAPAPLCGMILADFGARVVRVDRAPRSAVATDVQGRGKRSLALDLKRPPGAAALRRLCSGADVLIEPFRHGVMEKLGLGPEVLLHENPRLIYARLTGFGQTGKYAKSAGHDINYVALSGVLSKLGRKGENPYAPLNLLADFAGGGVLCALGIIIALYERTISGKGQVVDASMVEGIAYISSFLWKSQNLGLWNRPRGENLLDSGAPFYETYKTSDGKFMAVGAIEPQFYDQLIKGLGLDSDKLPSQLSFSDWPEMKKKFASIFAQKTQSEWCSIFDGTDACVTPVLSFDDAPLHQHNKQRSSFIKNDQEEISPRPAPLLSRTPAVPSCKRDPFIGEHTEEILLEYGFTQEEIAKLYSDKVIESNKLKANL", "length": 394, "header": "tr|F1NKY1-1|F1NKY1_CHICK Isoform 1 of Alpha-methylacyl-CoA racemase OS=Gallus gallus OX=9031 GN=AMACR PE=1 SV=2 CANONICAL=F1NKY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQU5-1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1/entry#A0A8V0YQU5-1", "sequence": { "sequence": "MPLRLVKEDLPLVKPCWFSPITSRPSMYLSIASRRICSMIFPDTEVRLTGVMEKLGLGPEVLLHENPRLIYARLTGFGQTGKYAKSAGHDINYVALSGVLSKLGRKGENPYAPLNLLADFAGGGVLCALGIIIALYERTISGKGQVVDASMVEGIAYISSFLWKSQNLGLWNRPRGENLLDSGAPFYETYKTSDGKFMAVGAIEPQFYDQLIKGLGLDSDKLPSQLSFSDWPEMKKKFASIFAQKTQSEWCSIFDGTDACVTPVLSFDDAPLHQHNKQRSSFIKNDQEEISPRPAPLLSRTPAVPSCKRDPFIGEHTEEILLEYGFTQEEIAKLYSDKVIESNKLKANL", "length": 349, "header": "tr|A0A8V0YQU5-1|F1NKY1_CHICK Computationally mapped isoform of Alpha-methylacyl-CoA racemase OS=Gallus gallus OX=9031 GN=AMACR PE=1 SV=1 CANONICAL=F1NKY1-1" }, "locus": { "chromosome": "Z", "start_pos": 10920794, "end_pos": 10903736, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031694.1", "url": "https://www.ensembl.org/id/ENSGALT00010031694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018542.1", "url": "https://www.ensembl.org/id/ENSGALP00010018542.1" } ] } }, { "isoform_ac": "F1NKY1-1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1/entry#F1NKY1-1", "sequence": { "sequence": "MFRRSAGGGRSMALSGLRVLELAGLAPAPLCGMILADFGARVVRVDRAPRSAVATDVQGRGKRSLALDLKRPPGAAALRRLCSGADVLIEPFRHGVMEKLGLGPEVLLHENPRLIYARLTGFGQTGKYAKSAGHDINYVALSGVLSKLGRKGENPYAPLNLLADFAGGGVLCALGIIIALYERTISGKGQVVDASMVEGIAYISSFLWKSQNLGLWNRPRGENLLDSGAPFYETYKTSDGKFMAVGAIEPQFYDQLIKGLGLDSDKLPSQLSFSDWPEMKKKFASIFAQKTQSEWCSIFDGTDACVTPVLSFDDAPLHQHNKQRSSFIKNDQEEISPRPAPLLSRTPAVPSCKRDPFIGEHTEEILLEYGFTQEEIAKLYSDKVIESNKLKANL", "length": 394, "header": "tr|F1NKY1-1|F1NKY1_CHICK Isoform 1 of Alpha-methylacyl-CoA racemase OS=Gallus gallus OX=9031 GN=AMACR PE=1 SV=2 CANONICAL=F1NKY1-1" }, "locus": { "chromosome": "Z", "start_pos": 10924044, "end_pos": 10903736, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031696.1", "url": "https://www.ensembl.org/id/ENSGALT00010031696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018544.1", "url": "https://www.ensembl.org/id/ENSGALP00010018544.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-193368", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193368", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol" }, { "id": "R-GGA-193775", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193775", "resource": "Reactome", "description": "Synthesis of bile acids and bile salts via 24-hydroxycholesterol" }, { "id": "R-GGA-389887", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389887", "resource": "Reactome", "description": "Beta-oxidation of pristanoyl-CoA" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "isomerase activity", "id": "GO:0016853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853", "evidence": [ { "database": "UniProtKB", "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ], "pmid": "" }, { "name": "alpha-methylacyl-CoA racemase activity", "id": "GO:0008111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008111", "evidence": [ { "database": "UniProtKB", "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "bile acid metabolic process", "id": "GO:0008206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008206", "evidence": [ { "database": "UniProtKB", "id": "F1NKY1", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12657", "name": "", "equation": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "12657", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12657" } ] }, { "id": "40455", "name": "", "equation": "(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA = (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "40455", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40455" } ] }, { "id": "46732", "name": "", "equation": "(2R,6)-dimethylheptanoyl-CoA = (2S,6)-dimethylheptanoyl-CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "46732", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46732" } ] }, { "id": "R-GGA-192056", "name": "Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-192308" ], "output_participant_list": [], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "R-GGA-192056", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-192056" } ] }, { "id": "R-GGA-193452", "name": "Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-193429" ], "output_participant_list": [], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "R-GGA-193452", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193452" } ] }, { "id": "R-GGA-193736", "name": "Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-193732" ], "output_participant_list": [ "R-ALL-193732" ], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "R-GGA-193736", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193736" } ] }, { "id": "R-GGA-193763", "name": "Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-193793" ], "output_participant_list": [ "R-ALL-193422" ], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "R-GGA-193763", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193763" } ] }, { "id": "R-GGA-389897", "name": "Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-389569" ], "output_participant_list": [], "enzyme_list": [ "F1NKY1-1" ], "evidence": [ { "id": "R-GGA-389897", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389897" } ] }, { "id": "R-GGA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033235" } ] }, { "id": "R-GGA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-192308", "participant_name": "25(R) THCA-CoA [peroxisomal matrix]", "crossref": [ { "id": "37642", "database": "ChEBI", "url": "" }, { "id": "HMDB0060305", "database": "HMDB Metabolite", "url": "" }, { "id": "C15613", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-193422", "participant_name": "(24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA [peroxisomal matrix]", "crossref": [ { "id": "HMDB0062224", "database": "HMDB Metabolite", "url": "" }, { "id": "52050", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-193429", "participant_name": "25(R) DHCA-CoA [peroxisomal matrix]", "crossref": [ { "id": "15494", "database": "ChEBI", "url": "" }, { "id": "C04644", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-193732", "participant_name": "3,7,24THCA-CoA [peroxisomal matrix]", "crossref": [ { "id": "27403", "database": "ChEBI", "url": "" }, { "id": "C05448", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-193793", "participant_name": "25(R) TetraHCA-CoA [peroxisomal matrix]", "crossref": [ { "id": "27458", "database": "ChEBI", "url": "" }, { "id": "HMDB0006890", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-389569", "participant_name": "(2R) Pristanoyl-CoA [peroxisomal matrix]", "crossref": [ { "id": "77250", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5PZB7", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] } ] }, { "uniprot_ac": "A0A1L1RJ90", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] } ] }, { "uniprot_ac": "A0A8V0XEK2", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] } ] }, { "uniprot_ac": "A0A8V0XIT0", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] } ] }, { "uniprot_ac": "A0A8V0XXY0", "gene_name": "MLYCD", "activity": [ { "ec_number": "4.1.1.9", "activity": "malonyl-CoA + H(+) = acetyl-CoA + CO2.", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] }, { "ec_number": "4.1.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] } ] }, { "uniprot_ac": "A0A8V0Y1Q3", "gene_name": "NUDT7", "activity": [ { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] } ] }, { "uniprot_ac": "A0A8V0Y2T0", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] } ] }, { "uniprot_ac": "A0A8V0YAP6", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] } ] }, { "uniprot_ac": "A0A8V0YMJ0", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZC97", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] } ] }, { "uniprot_ac": "A0A8V0ZI42", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] } ] }, { "uniprot_ac": "A0A8V0ZIT7", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] } ] }, { "uniprot_ac": "A0A8V0ZLD0", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD0" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQU7", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZRI7", "gene_name": "LONP2", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI7" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V1A097", "gene_name": "HAO2", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] } ] }, { "uniprot_ac": "A0A8V1A124", "gene_name": "AGXT", "activity": [ { "ec_number": "2.6.1.51", "activity": "L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.51", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] } ] }, { "uniprot_ac": "A0A8V1A248", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] } ] }, { "uniprot_ac": "A0A8V1A8Z1", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] } ] }, { "uniprot_ac": "A0A8V1AJL7", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] } ] }, { "uniprot_ac": "A0A8V1ANC5", "gene_name": "PIPOX", "activity": [ { "ec_number": "1.5.3.1", "activity": "sarcosine + O2 + H2O = formaldehyde + glycine + H2O2.", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "L-pipecolate + O2 = L-1-piperideine-6-carboxylate + H2O2 + H(+).", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.1", "activity": "", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] } ] }, { "uniprot_ac": "E1BRR7", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] } ] }, { "uniprot_ac": "F1N9G6", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] } ] }, { "uniprot_ac": "F1NG68", "gene_name": "DECR2", "activity": [ { "ec_number": "1.3.1.124", "activity": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] }, { "ec_number": "1.3.1.124", "activity": "", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] } ] }, { "uniprot_ac": "F1NKY1", "gene_name": "AMACR", "activity": [ { "ec_number": "5.1.99.4", "activity": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] }, { "ec_number": "5.1.99.4", "activity": "", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] } ] }, { "uniprot_ac": "Q5ZL13", "gene_name": "NUDT19", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] } ] } ], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NKY1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 394, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NKY1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NKY1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.1.99.4", "ec_name": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "5.1.99.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.1.99.4" }, { "id": "5.1.99.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.1.99.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C8A2-1", "uniprot_ac": "E1C8A2", "uniprot_id": "E1C8A2_CHICK", "mass": { "chemical_mass": 52220.0, "monoisotopic_mass": 52220.0 }, "refseq": { "ac": "NP_001264959", "name": "sorting and assembly machinery component 50 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264959" }, "gene_names": [ { "name": "SAMM50", "type": "recommended", "evidence": [ { "id": "E1C8A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8A2" } ] }, { "name": "SAMM50", "type": "synonym", "evidence": [ { "id": "NP_001264959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264959" } ] } ], "protein_names": [ { "name": "SAMM50 sorting and assembly machinery component", "type": "synonym", "evidence": [ { "id": "E1C8A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8A2/entry#names_and_taxonomy" } ] }, { "name": "sorting and assembly machinery component 50 homolog", "type": "synonym", "evidence": [ { "id": "NP_001264959", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264959" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01000280.1, HAEK01012943.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1, BX950332.1, BU316017.1, CV039507.1 and BU337318.1. On May 5, 2013 this sequence version replaced XP_416458.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264959", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264959" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C8A2", "url": "https://www.uniprot.org/uniprotkb/E1C8A2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAMM50", "url": "https://www.uniprot.org/uniprotkb/E1C8A2", "locus": { "chromosome": "1", "start_pos": 69194450, "end_pos": 69173521, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013278", "url": "https://www.ensembl.org/id/ENSGALG00010013278" } ] } } ], "crossref": [ { "id": "E1C8A2", "url": "https://alphafold.ebi.ac.uk/entry/E1C8A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014194", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014194", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418234", "url": "https://www.ncbi.nlm.nih.gov/gene/418234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418234", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHPVARF", "url": "https://omabrowser.org/oma/group/KHPVARF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PGC2", "url": "https://www.orthodb.org/?gene=A0A1D5PGC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YRE0", "url": "https://www.orthodb.org/?gene=A0A8V0YRE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C8A2", "url": "https://www.orthodb.org/?gene=E1C8A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12815:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12815:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264959", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264959", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PGC2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PGC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8A2", "url": "https://www.uniprot.org/uniprotkb/E1C8A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8A2-1", "url": "https://www.uniprot.org/uniprotkb/E1C8A2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTVHARSLEPLPASGPDFGALGEEAELVEVEPEAKQEILENKDVVVQHVHFDGLGRTRDDIIMYEIADVFKAKNLIDVMRKSHEAREKLLRLGIFRQVEVLIDTCQGDDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKFPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFERNFSVNLYKVTGQFPWSSLRETDRGISTEFNFPIWKTNHTLKWEGVWRELGCLARTASFSVREESGHSLKSSISHAMVIDSRNSSILPKRGALLKINQELAGYTGGDVSFLKEDFEFQLNKQLLWDSVFSASLWGGMLVPIGDKPSSIADRFYLGGPTSVRGFSMYSIGPQSDGDYLGGEAYWAGGLHLYTPLPFRPGRGGFGDLFRTHFFLNAGNLCNLNYGDGPKAHLQKLAEYIRWSYGAGIVLRLGNIARLELNYCFPMGVQSGDRICDGVQFGAGIRFL", "length": 469, "header": "tr|E1C8A2-1|E1C8A2_CHICK Isoform 1 of SAMM50 sorting and assembly machinery component OS=Gallus gallus OX=9031 GN=SAMM50 PE=1 SV=1 CANONICAL=E1C8A2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PGC2-1", "url": "https://www.uniprot.org/uniprotkb/E1C8A2/entry#A0A1D5PGC2-1", "sequence": { "sequence": "MNCVTVVVVQHVHFDGLGRTRDDIIMYEIADVFKAKNLIDVMRKSHEAREKLLRLGIFRQVEVLIDTCQGDDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKFPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFERNFSVNLYKVTGQFPWSSLRETDRGISTEFNFPIWKTNHTLKWEGVWRELGCLARTASFSVREESGHSLKSSISHAMVIDSRNSSILPKRGALLKINQELAGYTGGDVSFLKEDFEFQLNKQLLWDSVFSASLWGGMLVPIGDKPSSIADRFYLGGPTSVRGFSMYSIGPQSDGDYLGGEAYWAGGLHLYTPLPFRPGRGGFGDLFRTHFFLNAGNLCNLNYGDGPKAHLQKLAEYIRWSYGAGIVLRLGNIARLELNYCFPMGVQSGDRICDGVQFGAGIRFL", "length": 431, "header": "tr|A0A1D5PGC2-1|A0A1D5PGC2_CHICK Computationally mapped isoform of SAMM50 sorting and assembly machinery component OS=Gallus gallus OX=9031 GN=SAMM50 PE=1 SV=2 CANONICAL=E1C8A2-1" }, "locus": { "chromosome": "1", "start_pos": 69191236, "end_pos": 69175771, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031929.1", "url": "https://www.ensembl.org/id/ENSGALT00010031929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018726.1", "url": "https://www.ensembl.org/id/ENSGALP00010018726.1" } ] } }, { "isoform_ac": "A0A8V0YRE0-1", "url": "https://www.uniprot.org/uniprotkb/E1C8A2/entry#A0A8V0YRE0-1", "sequence": { "sequence": "MGTVHARSLEPLPASGPDFGALGEEAELVEVEPEAKQEILENKDVVVQHVHFDGLGRTRDDIIMYEIADVFKAKNLIDVMRKSHEAREKLLRLGIFRQVEVLIDTCQGDDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKFPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFERNFSVNLYKVTGQFPWSSLRETDRGISTEFNFPIWKTNHTLKWEGVWRELGCLARTASFSVREESGHSLKSSISHAMVIDSRNSSILPKRGALLKINQELAGYTGGDVSFLKEDFEFQLNKQLLWDSVFSASLWGGMLVPIGDKPSSIADRFYLGGPTSVRGFSMYSIGPQSDGDYLGGEAYWAGGFGDLFRTHFFLNAGNLCNLNYGDGPKAHLQKLAEYIRWSYGAGIVLRLGNIARLELNYCFPMGVQSGDRICDGVQFGAGIRFL", "length": 454, "header": "tr|A0A8V0YRE0-1|E1C8A2_CHICK Computationally mapped isoform of SAMM50 sorting and assembly machinery component OS=Gallus gallus OX=9031 GN=SAMM50 PE=1 SV=1 CANONICAL=E1C8A2-1" }, "locus": { "chromosome": "1", "start_pos": 69191236, "end_pos": 69173632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031932.1", "url": "https://www.ensembl.org/id/ENSGALT00010031932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018729.1", "url": "https://www.ensembl.org/id/ENSGALP00010018729.1" } ] } }, { "isoform_ac": "E1C8A2-1", "url": "https://www.uniprot.org/uniprotkb/E1C8A2/entry#E1C8A2-1", "sequence": { "sequence": "MGTVHARSLEPLPASGPDFGALGEEAELVEVEPEAKQEILENKDVVVQHVHFDGLGRTRDDIIMYEIADVFKAKNLIDVMRKSHEAREKLLRLGIFRQVEVLIDTCQGDDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKFPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFERNFSVNLYKVTGQFPWSSLRETDRGISTEFNFPIWKTNHTLKWEGVWRELGCLARTASFSVREESGHSLKSSISHAMVIDSRNSSILPKRGALLKINQELAGYTGGDVSFLKEDFEFQLNKQLLWDSVFSASLWGGMLVPIGDKPSSIADRFYLGGPTSVRGFSMYSIGPQSDGDYLGGEAYWAGGLHLYTPLPFRPGRGGFGDLFRTHFFLNAGNLCNLNYGDGPKAHLQKLAEYIRWSYGAGIVLRLGNIARLELNYCFPMGVQSGDRICDGVQFGAGIRFL", "length": 469, "header": "tr|E1C8A2-1|E1C8A2_CHICK Isoform 1 of SAMM50 sorting and assembly machinery component OS=Gallus gallus OX=9031 GN=SAMM50 PE=1 SV=1 CANONICAL=E1C8A2-1" }, "locus": { "chromosome": "1", "start_pos": 69191236, "end_pos": 69173632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031936.1", "url": "https://www.ensembl.org/id/ENSGALT00010031936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018732.1", "url": "https://www.ensembl.org/id/ENSGALP00010018732.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418234", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AXV4-1", "protein_name": "Sorting and assembly machinery component 50 homolog", "gene_name": "Samm50", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTVHARSLEPLPSSGTDFGALGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLERTKDDIIICEIGEVFKAKNLIEVMRRSHEAREKLLRLGIFRQVDVLIDTCHGEDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFEKNFSVNLYKVTGQFPWSSLRETDRGVSAEYSFPLCKTSHTVKWEGVWRELGCLARTASFAVRKESGHSLKSSLSHAMVIDSRNSSILPRRGALLKVNQELAGYTGGDVSFIKEDFELQLNKPLVLDSVFSTSLWGGMLVPIGDKLSSIADRFYLGGPTSVRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPRAHIRKLAECIRWSYGAGIVLRLGNIARLELNYCIPMGVQRGDRICDGVQFGAGIRFL", "length": 469 }, "evidence": [ { "id": "E1C8A2", "url": "https://omabrowser.org/oma/group/E1C8A2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGH2-1", "protein_name": "Sorting and assembly machinery component 50 homolog", "gene_name": "Samm50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTVHARSLEPLPSSGTDFGALGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLGRTKDDIIICEIGEVFKAKNLIEVMRRSHEAREKLLRLGIFRQVDVLIDTCHGEDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFERNFSVNLYKVTGQFPWSSLRETDRGVSAEYSFPLWKTSHTVKWEGVWRELGCLSRTASFAVRKESGHSLKSSLSHAMVIDSRNSSILPRRGALFKVNQELAGYTGGDVSFIKEDFELQLNKPLALDSVFSTSLWGGMLVPIGDKPSSIADRFYLGGPTSVRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGVVLRLGNIARLELNYCIPMGVQGGDRICDGVQFGAGIRFL", "length": 469 }, "evidence": [ { "id": "E1C8A2", "url": "https://omabrowser.org/oma/group/E1C8A2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFG3-1", "protein_name": "Outer membrane OMP85 family protein", "gene_name": "MOP10.6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MENPAEKPDPNPSKPKIESEDEREELGDINGDEEEEEEYEEEDDGKPRTREDAIADRIKAESLFRRMRATPVAVRVHDVIVKGNEKTKDHVIEAEVDVVRQATTLQELLKASKVANFNLQALDIFDSVKITLDSGPPELPGTTNVVIDVVESKSPITGQIGTFTKAEARSSSLEGSLKYKNIFGYGDIWDGSLAYGCDHSAEVGLGMYLPRFRGRPTPFTSRVYLSTQDWLKFSSYKERALGLSLGLIASKYHELAYNIAWRNLIDPSQMASRSIRRQLGHNLVSALKYTFKFDQRNSSLRPTRGYSFISTSQIGGLAPDSRTLRFLRQEIDLRYAVPLGFYRAALNFGIAGGITFPWGSGYKSRASCVPERFFLGGNISPVCSLGGPSALWGFKTRGLGPNEPRREVQDDESGDTYERDFVGGDVAVTAFADLSFDFPLKWFRDRGIHGHVFACAGNMAELSENKYRNFTAPKLLETFRSSVGAGIVVPTSLFRMELNYCHILKKQEHDRAKSGFFMTFSTSS", "length": 524 }, "evidence": [ { "id": "E1C8A2", "url": "https://omabrowser.org/oma/group/E1C8A2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y512-1", "protein_name": "Sorting and assembly machinery component 50 homolog", "gene_name": "SAMM50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTVHARSLEPLPSSGPDFGGLGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLGRTKDDIIICEIGDVFKAKNLIEVMRKSHEAREKLLRLGIFRQVDVLIDTCQGDDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYGTKETSYGLSFFKPRPGNFERNFSVNLYKVTGQFPWSSLRETDRGMSAEYSFPIWKTSHTVKWEGVWRELGCLSRTASFAVRKESGHSLKSSLSHAMVIDSRNSSILPRRGALLKVNQELAGYTGGDVSFIKEDFELQLNKQLIFDSVFSASFWGGMLVPIGDKPSSIADRFYLGGPTSIRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGIVLRLGNIARLELNYCVPMGVQTGDRICDGVQFGAGIRFL", "length": 469 }, "evidence": [ { "id": "E1C8A2", "url": "https://omabrowser.org/oma/group/E1C8A2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "E1C8A2", "url": "https://www.uniprot.org/uniprotkb/E1C8A2" } ], "pmid": "" }, { "name": "SAM complex", "id": "GO:0001401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001401", "evidence": [ { "database": "UniProtKB", "id": "E1C8A2", "url": "https://www.uniprot.org/uniprotkb/E1C8A2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein insertion into mitochondrial outer membrane", "id": "GO:0045040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045040", "evidence": [ { "database": "UniProtKB", "id": "E1C8A2", "url": "https://www.uniprot.org/uniprotkb/E1C8A2" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "E1C8A2", "url": "https://www.uniprot.org/uniprotkb/E1C8A2" } ], "pmid": "" }, { "name": "protein import into mitochondrial matrix", "id": "GO:0030150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "evidence": [ { "database": "UniProtKB", "id": "E1C8A2", "url": "https://www.uniprot.org/uniprotkb/E1C8A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C8A2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 469, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C8A2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C8A2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 268, "end_pos": 270 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1N8W9-1", "uniprot_ac": "F1N8W9", "uniprot_id": "F1N8W9_CHICK", "mass": { "chemical_mass": 20189.0, "monoisotopic_mass": 20189.0 }, "refseq": { "ac": "NP_001185569", "name": "dynactin subunit 5 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185569" }, "gene_names": [ { "name": "DCTN5", "type": "recommended", "evidence": [ { "id": "F1N8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8W9" } ] }, { "name": "DCTN5", "type": "synonym", "evidence": [ { "id": "NP_001185569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185569" } ] } ], "protein_names": [ { "name": "Dynactin subunit 5", "type": "recommended", "evidence": [ { "id": "F1N8W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8W9/entry#names_and_taxonomy" } ] }, { "name": "dynactin 4", "type": "synonym", "evidence": [ { "id": "NP_001185569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185569" } ] }, { "name": "dynactin 5 (p25)", "type": "synonym", "evidence": [ { "id": "NP_001185569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185569" } ] }, { "name": "dynactin subunit 5 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001185569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185569" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01035275.1, HAEK01011236.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1 and CN235561.1. Transcript Variant: This variant (2) has differences in the 3' UTR and 3' coding region that result in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001185569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185569" } ] }, { "annotation": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.", "evidence": [ { "database": "UniProtKB", "id": "F1N8W9", "url": "https://www.uniprot.org/uniprotkb/F1N8W9#function" }, { "database": "UniProtKB", "id": "ARBA00034687", "url": "https://www.uniprot.org/uniprotkb/ARBA00034687#function" }, { "database": "UniProtKB", "id": "A0A8V0YSZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1N8W9", "url": "https://www.uniprot.org/uniprotkb/F1N8W9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCTN5", "url": "https://www.uniprot.org/uniprotkb/F1N8W9", "locus": { "chromosome": "14", "start_pos": 6904892, "end_pos": 6898161, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017096", "url": "https://www.ensembl.org/id/ENSGALG00010017096" } ] } } ], "crossref": [ { "id": "F1N8W9", "url": "https://alphafold.ebi.ac.uk/entry/F1N8W9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006088", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006088", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03359", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03359", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416574", "url": "https://www.ncbi.nlm.nih.gov/gene/416574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQIHGTQ", "url": "https://omabrowser.org/oma/group/SQIHGTQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YSZ1", "url": "https://www.orthodb.org/?gene=A0A8V0YSZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N8W9", "url": "https://www.orthodb.org/?gene=F1N8W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46126:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46126:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001185569", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001185569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YSZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YSZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8W9", "url": "https://www.uniprot.org/uniprotkb/F1N8W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8W9-1", "url": "https://www.uniprot.org/uniprotkb/F1N8W9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSEMLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHIGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQV", "length": 182, "header": "tr|F1N8W9-1|F1N8W9_CHICK Isoform 1 of Dynactin subunit 5 OS=Gallus gallus OX=9031 GN=DCTN5 PE=1 SV=3 CANONICAL=F1N8W9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YSZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1N8W9/entry#A0A8V0YSZ1-1", "sequence": { "sequence": "MELSEMLYNKSEYIETVRGAVCGSGWRGWALGSGLWAGLGSARLGDCLFSPQASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHIGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQVASARV", "length": 223, "header": "tr|A0A8V0YSZ1-1|F1N8W9_CHICK Computationally mapped isoform of Dynactin subunit 5 OS=Gallus gallus OX=9031 GN=DCTN5 PE=1 SV=1 CANONICAL=F1N8W9-1" }, "locus": { "chromosome": "14", "start_pos": 6904190, "end_pos": 6898181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041269.1", "url": "https://www.ensembl.org/id/ENSGALT00010041269.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024160.1", "url": "https://www.ensembl.org/id/ENSGALP00010024160.1" } ] } }, { "isoform_ac": "F1N8W9-1", "url": "https://www.uniprot.org/uniprotkb/F1N8W9/entry#F1N8W9-1", "sequence": { "sequence": "MELSEMLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHIGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQV", "length": 182, "header": "tr|F1N8W9-1|F1N8W9_CHICK Isoform 1 of Dynactin subunit 5 OS=Gallus gallus OX=9031 GN=DCTN5 PE=1 SV=3 CANONICAL=F1N8W9-1" }, "locus": { "chromosome": "14", "start_pos": 6901026, "end_pos": 6898181, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041266.1", "url": "https://www.ensembl.org/id/ENSGALT00010041266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024159.1", "url": "https://www.ensembl.org/id/ENSGALP00010024159.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZK88-1", "protein_name": "Dynactin subunit 5", "gene_name": "DCTN5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQV", "length": 182 }, "evidence": [ { "id": "F1N8W9", "url": "https://omabrowser.org/oma/group/F1N8W9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9BTE1-1", "protein_name": "Dynactin subunit 5", "gene_name": "DCTN5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQV", "length": 182 }, "evidence": [ { "id": "F1N8W9", "url": "https://omabrowser.org/oma/group/F1N8W9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZB9-1", "protein_name": "Dynactin subunit 5", "gene_name": "Dctn5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQV", "length": 182 }, "evidence": [ { "id": "F1N8W9", "url": "https://omabrowser.org/oma/group/F1N8W9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJQ6-1", "protein_name": "Dynactin subunit 5", "gene_name": "DCTN5-p25", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEIPDTYYSKDEYVETASGNKVSRHTVLCGSQNIILNGKVIVQSGAIIRGDLANVRTGRYCVIGKNSVIRPPYKQFSKGIAFFPMHVGEHVFVGEGAVVSAATIGSYVYIGKNAIIGRRCVLKDCCVIEDGAVLPPETTVSSYMRYTARGTIEGGQGNPYFVPAAMQDEMINYTKSFYEHFVRAPAPAS", "length": 189 }, "evidence": [ { "id": "F1N8W9", "url": "https://omabrowser.org/oma/group/F1N8W9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1N8W9", "url": "https://www.uniprot.org/uniprotkb/F1N8W9" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "F1N8W9", "url": "https://www.uniprot.org/uniprotkb/F1N8W9" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1N8W9", "url": "https://www.uniprot.org/uniprotkb/F1N8W9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NNH5-1", "uniprot_ac": "F1NNH5", "uniprot_id": "F1NNH5_CHICK", "mass": { "chemical_mass": 115080.0, "monoisotopic_mass": 115080.0 }, "refseq": { "ac": "XP_004947311", "name": "teashirt homolog 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947311" }, "gene_names": [ { "name": "TSHZ2", "type": "recommended", "evidence": [ { "id": "F1NNH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ] }, { "name": "TSHZ2", "type": "synonym", "evidence": [ { "id": "XP_004947311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947311" } ] } ], "protein_names": [ { "name": "Teashirt zinc finger homeobox 2", "type": "synonym", "evidence": [ { "id": "F1NNH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH5/entry#names_and_taxonomy" } ] }, { "name": "teashirt homolog 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004947311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947311" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947311" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSHZ2", "url": "https://www.uniprot.org/uniprotkb/F1NNH5", "locus": { "chromosome": "20", "start_pos": 12889850, "end_pos": 13103853, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015734", "url": "https://www.ensembl.org/id/ENSGALG00010015734" } ] } } ], "crossref": [ { "id": "F1NNH5", "url": "https://alphafold.ebi.ac.uk/entry/F1NNH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007809", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007809", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419341", "url": "https://www.ncbi.nlm.nih.gov/gene/419341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419341", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TGHYQDN", "url": "https://omabrowser.org/oma/group/TGHYQDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YT24", "url": "https://www.orthodb.org/?gene=A0A8V0YT24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUX8", "url": "https://www.orthodb.org/?gene=A0A8V0YUX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NNH5", "url": "https://www.orthodb.org/?gene=F1NNH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12487:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12487:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947311", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YT24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YT24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NNH5-1", "url": "https://www.uniprot.org/uniprotkb/F1NNH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRKQQAPKRAAGYVQEEDLKEEEDIKEEEEDDDDNSTAQLQGSNDTGTDEEHDVGPEQKGNFSYQNSPVSHISNQDAENESLLSDGSDHVTDIKSICSREPQDPKTSTHPKAQNEAHNCMDKMTAVYANILSDSYWTGLGLGFKLSNSEKRSCDNRNGGNKADFDWHQDALSKSLQQNLPSRPVSKPNLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNHKKDKHRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFSDTFSPQKNGNLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPASDSPVSKSIGKSSSAECIAPASEIKKESKKDKADDANKDEKAVKTEEYEDALQKPLDPTMKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGAKPSLPVGSQVLQIRPTMANKLRPIAPKWKVMPLVPISANVAQCTQLKKETDDREEVQKDYAKESIQAEPVSLSQSEREPILKSEACVEPKNTEPCPLKEEDKIKEDSGKEKSALKESTAASLSNGCAAASHSSELPCVNPLSALQSVLNNHLGKATEPLRPQSNSSPSSSTISMFHKSNLNMMEKPVLSPTPTPPKPASVTRHYLFENNDQPIDLTKSKGKKAESAQAQSCTSPPQKHALSDIADMVKVLPKATTPKPAASSRIPSMKLEIDVRRFEDVSTEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPVFYCSDCASQFRTPSTYISHLESHLGFQMKDMNRLAVEQQTKVEQEISRVSVQRSPETIAGEEDTDSKFKCKLCCRTFASKHAVKLHLSKTHSKSPEHHSQFVAEVDEE", "length": 1036, "header": "tr|F1NNH5-1|F1NNH5_CHICK Isoform 1 of Teashirt zinc finger homeobox 2 OS=Gallus gallus OX=9031 GN=TSHZ2 PE=3 SV=2 CANONICAL=F1NNH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YT24-1", "url": "https://www.uniprot.org/uniprotkb/F1NNH5/entry#A0A8V0YT24-1", "sequence": { "sequence": "MPRRKQQAPKRAAGYVQEEDLKEEEDIKEEEEDDDDNSTAQLQGSNDTGTDEEHDVGPEQKGNFSYQNSPVSHISNQDAENESLLSDGSDHVTDIKSICSREPQDPKTSTHPKAQNEAHNCMDKMTAVYANILSDSYWTGLGLGFKLSNSEKRSCDNRNGGNKADFDWHQDALSKSLQQNLPSRPVSKPNLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNHKKDKHRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFSDTFSPQKNGNLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPASDSPVSKSIGKSSSAECIAPASEIKKESKKDKADDANKDEKAVKTEEYEDALQKPLDPTMKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGAKPSLPVGSQVLQIRPTMANKLRPIAPKWKVMPLVPISANVAQCTQLKKETDDREEVQKDYAKESIQAEPVSLSQSEREPILKSEACVEPKNTEPCPLKEEDKIKEDSGKEKSALKESTAASLSNGCAAASHSSELPCVNPLSALQSVLNNHLGKATEPLRPQSNSSPSSSTISMFHKSNLNMMEKPVLSPTPTPPKPASVTRHYLFENNDQPIDLTKSKGKKAESAQAQSCTSPPQKHALSDIADMVKVLPKATTPKPAASSRIPSMKLEIDVRRFEDVSTEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPVFYCSDCASQFRTPSTYISHLESHLGFQMKDMNRLAVEQQTKVEQEISRVSVQRSPETIAGEEDTDSKFK", "length": 997, "header": "tr|A0A8V0YT24-1|F1NNH5_CHICK Computationally mapped isoform of Teashirt zinc finger homeobox 2 OS=Gallus gallus OX=9031 GN=TSHZ2 PE=3 SV=1 CANONICAL=F1NNH5-1" }, "locus": { "chromosome": "20", "start_pos": 13103706, "end_pos": 12971227, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037878.1", "url": "https://www.ensembl.org/id/ENSGALT00010037878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021861.1", "url": "https://www.ensembl.org/id/ENSGALP00010021861.1" } ] } }, { "isoform_ac": "A0A8V0YUX8-1", "url": "https://www.uniprot.org/uniprotkb/F1NNH5/entry#A0A8V0YUX8-1", "sequence": { "sequence": "MPRRKQQAPKRAAGYVQEEDLKEEEDIKEEEEDDDDNSTAQLQGSNDTGTDEEHDVGPEQKGNFSYQNSPVSHISNQDAENESLLSDGSDHVTDIKSICSREPQDPKTSTHPKAQNEAHNCMDKMTAVYANILSDSYWTGLGLGFKLSNSEKRSCDNRNGGNKADFDWHQDALSKSLQQNLPSRPVSKPNLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNHKKDKHRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFSDTFSPQKNGNLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPASDSPVSKSIGKSSSAECIAPASEIKKESKKDKADDANKDEKAVKTEEYEDALQKPLDPTMKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGAKPSLPVGSQVLQIRPTMANKLRPIAPKWKVMPLVPISANVAQCTQLKKETDDREEVQKDYAKESIQAEPVSLSQSEREPILKSEACVEPKNTEPCPLKEEDKIKEDSGKEKSALKESTAASLSNGCAAASHSSELPCVNPLSALQSVLNNHLGKATEPLRPQSNSSPSSSTISMFHKSNLNMMEKPVLSPTPTPPKPASVTRHYLFENNDQPIDLTKSKGKKAESAQAQSCTSPPQKHALSDIADMVKVLPKATTPKPAASSRIPSMKLEIDVRRFEDVSTEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPVFYCSDCASQFRTPSTYISHLESHLGFQMKDMNRLAVEQQTKVEQEISRVSVQRSPETIAGEEDTDSKFKCFVSLSYPEMYLRHKSVPLGVPLPCTATLAHRCAKKGGEKKRRKRRGGRKKKKKKKKKKKKAAFH", "length": 1062, "header": "tr|A0A8V0YUX8-1|F1NNH5_CHICK Computationally mapped isoform of Teashirt zinc finger homeobox 2 OS=Gallus gallus OX=9031 GN=TSHZ2 PE=3 SV=1 CANONICAL=F1NNH5-1" }, "locus": { "chromosome": "20", "start_pos": 13103706, "end_pos": 12951499, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037879.1", "url": "https://www.ensembl.org/id/ENSGALT00010037879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021862.1", "url": "https://www.ensembl.org/id/ENSGALP00010021862.1" } ] } }, { "isoform_ac": "F1NNH5-1", "url": "https://www.uniprot.org/uniprotkb/F1NNH5/entry#F1NNH5-1", "sequence": { "sequence": "MPRRKQQAPKRAAGYVQEEDLKEEEDIKEEEEDDDDNSTAQLQGSNDTGTDEEHDVGPEQKGNFSYQNSPVSHISNQDAENESLLSDGSDHVTDIKSICSREPQDPKTSTHPKAQNEAHNCMDKMTAVYANILSDSYWTGLGLGFKLSNSEKRSCDNRNGGNKADFDWHQDALSKSLQQNLPSRPVSKPNLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNHKKDKHRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFSDTFSPQKNGNLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPASDSPVSKSIGKSSSAECIAPASEIKKESKKDKADDANKDEKAVKTEEYEDALQKPLDPTMKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGAKPSLPVGSQVLQIRPTMANKLRPIAPKWKVMPLVPISANVAQCTQLKKETDDREEVQKDYAKESIQAEPVSLSQSEREPILKSEACVEPKNTEPCPLKEEDKIKEDSGKEKSALKESTAASLSNGCAAASHSSELPCVNPLSALQSVLNNHLGKATEPLRPQSNSSPSSSTISMFHKSNLNMMEKPVLSPTPTPPKPASVTRHYLFENNDQPIDLTKSKGKKAESAQAQSCTSPPQKHALSDIADMVKVLPKATTPKPAASSRIPSMKLEIDVRRFEDVSTEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPVFYCSDCASQFRTPSTYISHLESHLGFQMKDMNRLAVEQQTKVEQEISRVSVQRSPETIAGEEDTDSKFKCKLCCRTFASKHAVKLHLSKTHSKSPEHHSQFVAEVDEE", "length": 1036, "header": "tr|F1NNH5-1|F1NNH5_CHICK Isoform 1 of Teashirt zinc finger homeobox 2 OS=Gallus gallus OX=9031 GN=TSHZ2 PE=3 SV=2 CANONICAL=F1NNH5-1" }, "locus": { "chromosome": "20", "start_pos": 13103706, "end_pos": 12971111, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010037880.1", "url": "https://www.ensembl.org/id/ENSGALT00010037880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021863.1", "url": "https://www.ensembl.org/id/ENSGALP00010021863.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 746, "start_aa": "Thr", "end_pos": 746, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr746", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 748, "start_aa": "Thr", "end_pos": 748, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr748", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419341", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TDG1-1", "protein_name": "Teashirt homolog 2 isoform X3", "gene_name": "tshz2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERAQRDFYFIMRQSAILELHRKSYEPDDEVGVQESIEEEEGENAMQTEEENSERPTSKDKDDKDIDNKSSYSFQNSPVSVLSNQEVELESRLSDGSDRLSDFKTSPPGSQKDTETQSSKLKDDMHSSLEKMRAAYANFLSDSYWSKIGLDLKVANTGSKANCDSTNGSTKSEFDWHQDALSKTLQQTLSPKPVSKPNLFSSVHLYRQNSKACGAVFTGASRFRCKDCSAAYDTLVELTVHMNKSGHYQDDNHSRQNIASTSSSKNRKRNLQDMEGKEDAQKVLKCMFCGHSFDSLQDLSVHMIKTKHYQKVPLKEPIPVITPKLIPPAKKRAFEATRPCSPDSTTGVSGYTDAQRSSGLANAPNNRYGYQNGASYTWQFETCKSQILKCMECGSSHDTLQQLTTHMMVTGHFIKVTNSASKKGKQLALDPLAIEKMQTLAEPTVNELEGEKVSPKSTASGDSERATPRDMSPDKAEKNEDKDDKQDEEERKPTDGNFKYPYLREEDLEQQGSSGGGDILKSLANTVASAINKAQTGTPSWSAYPSIHAAYQLSGVIKTASFSPSPPIQLKQNLNHKHRPIAPKGKFYQALRGLESFQGHHNSDIKKERGGASDGKESQSSRFDLVENDDSDCQDDSSSSSKLDADCVSEENDTIKGKLSPAFSDRGNPSPSPPASNGHSTSSELVNDSQEVLSINPLSALQSVLNNHLGKANKPRPESILSHRTQSIFSELSRGLEKPLSASAAIRASNSFMFTNDDQPIDLTKHKHNKPNSSLLLQSSTPMHQKHALSDIADMVKVLPKATTPKPPMPARMPVMKLETDVRRFEDVSSEMYSVHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMHISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDTGHPVFYCNDCASQFRTPSAFISHLENHLGFQIKDMNKLPIEHPTKITEPELSKVLTIRPTDSQITEEESDSKFKCKLCSRTFASNHAVKLHLSKTHSKSPENHSQFVEMDKE", "length": 1030 }, "evidence": [ { "id": "F1NNH5", "url": "https://omabrowser.org/oma/group/F1NNH5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0KYY4-1", "protein_name": "Teashirt zinc finger homeobox 2", "gene_name": "Tshz2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFFLNYVAPCRPGPFFLDKESTSWNIGEDIYEPAERRSLTHIGKVHIIPTSMLLPSPAPPPTPLFCSTERLEGKGILETTQLPTSKLQGRYAQEEVLKEEEEIKEEEEEDEDSGSVAQHQGSNDTGTDEELETGPEQKGYFSCQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCSRDAPDKKANPHAKLPSEPHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGSSKNDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQNSKMCGSVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKDDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVAPAKKRVFDVNRPCSPDSTTGSLADSFSSQKSANLQLPSNSRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSESPNSESLAPKPSSNSPSESTASATELKKESKKEKGEINEDEQGVKNEEYEDALQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPMAMGSQILQIRPNLANKLRPIAPKWKGMPLGPVPASLALYTQVKKEAEDKEEVMKQCRKESPHEEATSFSQPESESFSKIEPPSESRKAESCPLKEEEKLLKEKPEPLEPVSSLTNGCAVANHSPALPSINPLSALQSVLNNHLGKATEPLRSPSCSSPNSSTIPMFHKSSLGVVDKPVISPTSTRPAASVSRHYLFENTDQPIDLTKSKSKRAESSQAQSCTSPPQKHALCDIADMVKVLPKATTPKPAASSRVPPVKLEIDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRMAADQQSKVEQEISRVSSAQRSPETIADEEDTDSKFKCKLCSRTFVSKHAVKLHLSKTHSKSPEHHAQFVTDVDEE", "length": 1107 }, "evidence": [ { "id": "F1NNH5", "url": "https://omabrowser.org/oma/group/F1NNH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FE9-1", "protein_name": "Teashirt homolog 2", "gene_name": "Tshz2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRRKQQAPKRAAGYAQEEVLKEEEEIKEEEEEEEDSGSVAQHQSSNDTGTDEELETGPEQKGYFSCQNSPGSHLSNQDAENESLLSDASDQVSDVKSVCGRDVSDKKANTHPKLPSEPHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNSSGKNDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKLCGSVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSLADSFSSQKSANLQLPSNSRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSETPNSESLAPKPSSNSPSECTASTTELKKESKKEKGEGIEDEQGVKSEDYEDSLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPMAMGSQILQIRPNLANKLRPIAPKWKGMPLGPVPTSLALYTQVKKETEDKDEVVKQCGKESPHEEATSFSQPEGESFSKIEPPSESRKAEPCPLKEEEKPQKEKPEPLEPVSSLTNGCAPANHTPALPSINPLSALQSVLNNHLGKATEPLRSPSCSSPNSSTSPVFHKSSLHVVDKPVISPTSTRPAASVARHYLFENTDQPIDLTKSKSKRAESSQAQSCTSPPQKHALCDIADMVKVLPKATTPKPAASSRVPPMKLEIDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRMAADQQSKVEQEISRVSSAQRSPETIAGEEDTDSKFKCKLCRRTFVSKHAVKLHLSKTHSKSPEHHSQFVADVDEE", "length": 1030 }, "evidence": [ { "id": "F1NNH5", "url": "https://omabrowser.org/oma/group/F1NNH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRE2-1", "protein_name": "Teashirt homolog 2", "gene_name": "TSHZ2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRRKQQAPKRAAGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQVKKESEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQAQSCMSPPQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLSVDQQSKVEQEISRVSSAQRSPETIAAEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDVDEE", "length": 1034 }, "evidence": [ { "id": "F1NNH5", "url": "https://omabrowser.org/oma/group/F1NNH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NNH5", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NNH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NNH5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 275, "end_pos": 304, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 746, 748 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NAU4-1", "uniprot_ac": "F1NAU4", "uniprot_id": "F1NAU4_CHICK", "mass": { "chemical_mass": 54186.0, "monoisotopic_mass": 54186.0 }, "refseq": { "ac": "NP_001264203", "name": "ras-GEF domain-containing family member 1C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264203" }, "gene_names": [ { "name": "RASGEF1C", "type": "recommended", "evidence": [ { "id": "F1NAU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAU4" } ] }, { "name": "RASGEF1C", "type": "synonym", "evidence": [ { "id": "NP_001264203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264203" } ] } ], "protein_names": [ { "name": "RasGEF domain family member 1C", "type": "synonym", "evidence": [ { "id": "F1NAU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAU4/entry#names_and_taxonomy" } ] }, { "name": "ras-GEF domain-containing family member 1C", "type": "synonym", "evidence": [ { "id": "NP_001264203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264203" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX950328.2, SRR13267652.13.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000256.1. On Mar 29, 2013 this sequence version replaced XP_414615.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264203" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NAU4", "url": "https://www.uniprot.org/uniprotkb/F1NAU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASGEF1C", "url": "https://www.uniprot.org/uniprotkb/F1NAU4", "locus": { "chromosome": "13", "start_pos": 13718189, "end_pos": 13651536, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015260", "url": "https://www.ensembl.org/id/ENSGALG00010015260" } ] } } ], "crossref": [ { "id": "F1NAU4", "url": "https://alphafold.ebi.ac.uk/entry/F1NAU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006076", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006076", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416296", "url": "https://www.ncbi.nlm.nih.gov/gene/416296", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416296", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416296", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PAMTPEG", "url": "https://omabrowser.org/oma/group/PAMTPEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YTK1", "url": "https://www.orthodb.org/?gene=A0A8V0YTK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYK7", "url": "https://www.orthodb.org/?gene=A0A8V0YYK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYL2", "url": "https://www.orthodb.org/?gene=A0A8V0YYL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NAU4", "url": "https://www.orthodb.org/?gene=F1NAU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264203", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264203", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YTK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YTK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAU4", "url": "https://www.uniprot.org/uniprotkb/F1NAU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAU4-1", "url": "https://www.uniprot.org/uniprotkb/F1NAU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQTLSSTSMFTPCSFSPHLHSSKEDEQGGLIFQDGNLTSASLDALIQHLIPTTDYYPEKAYIFTFLLSSRLFIEPHELLSRVCHKCIEQQRLDDPVLDKARIRKFGPKILQLLTEWTETFPYDFQEERMIGHLKDMIHRIAPCDEAYWKKMNQLLQTLNQKLATLSHGQEGIVKINAAVSDKLVAFKSKPPSIQREILSVCSDPYTLAQQLTHVELERLSHIGPEEFVQAFVHKDPLDGTKPCFSDQKTSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWSKVKTAKFFILEHQMDPTGNFYNYRTALRGAAHRSLTAHSNREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDANIIHYLHTAPIFTEDGLYLASYESESPENQTEKDRWKSLRSTILGKT", "length": 471, "header": "tr|F1NAU4-1|F1NAU4_CHICK Isoform 1 of RasGEF domain family member 1C OS=Gallus gallus OX=9031 GN=RASGEF1C PE=4 SV=3 CANONICAL=F1NAU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YTK1-1", "url": "https://www.uniprot.org/uniprotkb/F1NAU4/entry#A0A8V0YTK1-1", "sequence": { "sequence": "MSILLQTAATADLCVSATGAVFPNSGSVWCILQGSREDPSIEVVDALLPSLEGMPQTLSSTSMFTPCSFSPHLHSSKEDEQGGLIFQDGNLTSASLDALIQHLIPTTDYYPEKAYIFTFLLSSRLFIEPHELLSRVCHKCIEQQRLDDPVLDKARIRKFGPKILQLLTEWTETFPYDFQEERMIGHLKDMIHRIAPCDEAYWKKMNQLLQTLNQKLATLSHGQEGIVKINAAVSDKLVAFKSKPPSIQREILSVCSDPYTLAQQLTHVELERLSHIGPEEFVQAFVHKDPLDGTKPCFSDQKTSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWSKVKTAKFFILEHQMDPTGNFYNYRTALRGAAHRSLTAHSNREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDANIIHYLHTAPIFTEDGLYLASYESESPENQTEKDRWKSLRSTILGKT", "length": 524, "header": "tr|A0A8V0YTK1-1|F1NAU4_CHICK Computationally mapped isoform of RasGEF domain family member 1C OS=Gallus gallus OX=9031 GN=RASGEF1C PE=4 SV=1 CANONICAL=F1NAU4-1" }, "locus": { "chromosome": "13", "start_pos": 13716702, "end_pos": 13682215, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036740.1", "url": "https://www.ensembl.org/id/ENSGALT00010036740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021425.1", "url": "https://www.ensembl.org/id/ENSGALP00010021425.1" } ] } }, { "isoform_ac": "A0A8V0YYK7-1", "url": "https://www.uniprot.org/uniprotkb/F1NAU4/entry#A0A8V0YYK7-1", "sequence": { "sequence": "MHPRKEPHAILTSATLQLHSRFREGMPQTLSSTSMFTPCSFSPHLHSSKEDEQGGLIFQDGNLTSASLDALIQHLIPTTDYYPEKAYIFTFLLSSRLFIEPHELLSRVCHKCIEQQRLDDPVLDKARIRKFGPKILQLLTEWTETFPYDFQEERMIGHLKDMIHRIAPCDEAYWKKMNQLLQTLNQKLATLSHGQEGIVKINAAVSDKLVAFKSKPPSIQREILSVCSDPYTLAQQLTHVELERLSHIGPEEFVQAFVHKDPLDGTKPCFSDQKTSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWSKVKTAKFFILEHQMDPTGNFYNYRTALRGAAHRSLTAHSNREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDANIIHYLHTAPIFTEDGLYLASYESESPENQTEKDRWKSLRSTILGKT", "length": 496, "header": "tr|A0A8V0YYK7-1|F1NAU4_CHICK Computationally mapped isoform of RasGEF domain family member 1C OS=Gallus gallus OX=9031 GN=RASGEF1C PE=4 SV=1 CANONICAL=F1NAU4-1" }, "locus": { "chromosome": "13", "start_pos": 13716702, "end_pos": 13673864, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036738.1", "url": "https://www.ensembl.org/id/ENSGALT00010036738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021423.1", "url": "https://www.ensembl.org/id/ENSGALP00010021423.1" } ] } }, { "isoform_ac": "A0A8V0YYL2-1", "url": "https://www.uniprot.org/uniprotkb/F1NAU4/entry#A0A8V0YYL2-1", "sequence": { "sequence": "MKCQKNKGLSKEGMPQTLSSTSMFTPCSFSPHLHSSKEDEQGGLIFQDGNLTSASLDALIQHLIPTTDYYPEKAYIFTFLLSSRLFIEPHELLSRVCHKCIEQQRLDDPVLDKARIRKFGPKILQLLTEWTETFPYDFQEERMIGHLKDMIHRIAPCDEAYWKKMNQLLQTLNQKLATLSHGQEGIVKINAAVSDKLVAFKSKPPSIQREILSVCSDPYTLAQQLTHVELERLSHIGPEEFVQAFVHKDPLDGTKPCFSDQKTSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWSKVKTAKFFILEHQMDPTGNFYNYRTALRGAAHRSLTAHSNREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDANIIHYLHTAPIFTEDGLYLASYESESPENQTEKDRWKSLRSTILGKT", "length": 484, "header": "tr|A0A8V0YYL2-1|F1NAU4_CHICK Computationally mapped isoform of RasGEF domain family member 1C OS=Gallus gallus OX=9031 GN=RASGEF1C PE=4 SV=1 CANONICAL=F1NAU4-1" }, "locus": { "chromosome": "13", "start_pos": 13716702, "end_pos": 13651892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036744.1", "url": "https://www.ensembl.org/id/ENSGALT00010036744.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021428.1", "url": "https://www.ensembl.org/id/ENSGALP00010021428.1" } ] } }, { "isoform_ac": "F1NAU4-1", "url": "https://www.uniprot.org/uniprotkb/F1NAU4/entry#F1NAU4-1", "sequence": { "sequence": "MPQTLSSTSMFTPCSFSPHLHSSKEDEQGGLIFQDGNLTSASLDALIQHLIPTTDYYPEKAYIFTFLLSSRLFIEPHELLSRVCHKCIEQQRLDDPVLDKARIRKFGPKILQLLTEWTETFPYDFQEERMIGHLKDMIHRIAPCDEAYWKKMNQLLQTLNQKLATLSHGQEGIVKINAAVSDKLVAFKSKPPSIQREILSVCSDPYTLAQQLTHVELERLSHIGPEEFVQAFVHKDPLDGTKPCFSDQKTSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWSKVKTAKFFILEHQMDPTGNFYNYRTALRGAAHRSLTAHSNREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDANIIHYLHTAPIFTEDGLYLASYESESPENQTEKDRWKSLRSTILGKT", "length": 471, "header": "tr|F1NAU4-1|F1NAU4_CHICK Isoform 1 of RasGEF domain family member 1C OS=Gallus gallus OX=9031 GN=RASGEF1C PE=4 SV=3 CANONICAL=F1NAU4-1" }, "locus": { "chromosome": "13", "start_pos": 13716702, "end_pos": 13692791, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036741.1", "url": "https://www.ensembl.org/id/ENSGALT00010036741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021426.1", "url": "https://www.ensembl.org/id/ENSGALP00010021426.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416296", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416296", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZVN9-1", "protein_name": "RasGEF domain family, member 1C", "gene_name": "Rasgef1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRTLTASDMVTPGSLSPPPIDSTEGEQAGQPLLDGAPSSASLETLIQHLVPTADYYPEKAYIFTFLLSSRLFIEPRELLARVCHLCIEQQQLDKPVLDKARVRKFGAKLLQLLAEWTETFPRDFEEESTIGHLTDVVGRISPCDETYGNRMHQLLQTLHQKLASLGQGPEGLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAFVNKDPLAGTKPRFNDKTNNVEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFFILEHQMDPTGNFCNYRTALRGAAHRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDPSITHYLYTAPIFSEDGLYLASYESESPENQTEKERWKSLRSSILGKT", "length": 466 }, "evidence": [ { "id": "F1NAU4", "url": "https://omabrowser.org/oma/group/F1NAU4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N431-1", "protein_name": "Ras-GEF domain-containing family member 1C", "gene_name": "RASGEF1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQTLSASDMVTPGSLSPPPTEPTDGEQAGQPLLDGAPSSASLETLIQHLVPTADYYPEKAYIFTFLLSSRLFIEPRELLARVCHLCIEQQQLDKPVLDKARVRKFGPKLLQLLAEWTETFPRDFQEESTIGHLKDVVGRIAPCDEAYRKRMHQLLQALHQKLAALRQGPEGLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAFVNKDPLASTKPCFSDKTSNLEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVRTAKFFILEHQMDPTGNFCNYRTALRGAAHRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDASITHYLYTAPIFSEDGLYLASYESESPENQTEKERWKALRSSILGKT", "length": 466 }, "evidence": [ { "id": "F1NAU4", "url": "https://omabrowser.org/oma/group/F1NAU4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D300-1", "protein_name": "Ras-GEF domain-containing family member 1C", "gene_name": "Rasgef1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRTLTASDMVTPGSLSPPPTESTEGEQAGQPLLDGAPSSASLDTLIQHLVPTADYYPEKAYIFTFLLSSRLFIEPRELLARVCHLCIEQQQLDKPVLDKARVRKFGAKLLQLLAEWTETFPRDFEEESTIGHLTDVVGRISPCDETYGSRVHQLLQTLHQKLASLGQGPESLVGADKPISYRTKPPASIHRELLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAFVNKDPLAGTKPRFSDKTNNVEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFFILEHQMDPTGNFCNYRTALRGAAHRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDPSITHYLYTAPIFSEDGLYLASYESESPESQTEKERWKSLRSSILGKT", "length": 466 }, "evidence": [ { "id": "F1NAU4", "url": "https://omabrowser.org/oma/group/F1NAU4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NAU4", "url": "https://www.uniprot.org/uniprotkb/F1NAU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "F1NAU4", "url": "https://www.uniprot.org/uniprotkb/F1NAU4" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "F1NAU4", "url": "https://www.uniprot.org/uniprotkb/F1NAU4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "F1NAU4", "url": "https://www.uniprot.org/uniprotkb/F1NAU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 311, "end_pos": 313 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 453, "end_pos": 455 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C530-1", "uniprot_ac": "E1C530", "uniprot_id": "E1C530_CHICK", "mass": { "chemical_mass": 88441.0, "monoisotopic_mass": 88441.0 }, "refseq": {}, "gene_names": [ { "name": "CEP78", "type": "recommended", "evidence": [ { "id": "E1C530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 78 kDa", "type": "recommended", "evidence": [ { "id": "E1C530", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C530/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP78", "url": "https://www.uniprot.org/uniprotkb/E1C530", "locus": { "chromosome": "Z", "start_pos": 38578112, "end_pos": 38553581, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015894", "url": "https://www.ensembl.org/id/ENSGALG00010015894" } ] } } ], "crossref": [ { "id": "E1C530", "url": "https://alphafold.ebi.ac.uk/entry/E1C530", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015179", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015179", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24110:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24110:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YU29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YU35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C530-1", "url": "https://www.uniprot.org/uniprotkb/E1C530-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIVAELISCWKKLIFFFLILQKHLSSRKMIDSVKIRRQCMLDFYSHYEHLCAVQGSVPLKAVKTNLTQGTLDLTVDRIKAADWTPLLDAIRHDKTLTSVGIRSCHHQGLGESGAERYKTYFRRRIPAIRSKDLTGQLCKAIKGCLSISDVLKNLELQGLLLRERDLILLTKGLATTSSLESISLAHCPIGDGGLETVCQSMKNSATIRYVNFTGCSLTWRGAEHMANVLKHQAMKRHGEAWAESLRYRRPDLDYMTGLRRITFNCNMLVGDRGASAFADCLGEDLWLKALDLQHCGISNEGARSLLDALRTNTTLVVLDIRKNPLIDHVLMKNIIERVLMNGSSANSEYKWLSSPSSKDALKARPKKRTIVLGSGRKGKATIRIGLTSKKSVSPGKKTLSVKDSYSPKPLPPGTKGFLPWRTAERAKRCRGGPGDNSGELPLKIQMGIPVKVTVESASTSETEETEDLEDVIHHPDLTKSVDKVNVTKYQQFQLELEECMEKLKEERRARVKAEERIMELEVENARLRNLNTSLSEALHVQSVTNMILEDEGVLGSIENSFQKFHAFLDLLKDAGLGQLAVLAGIDQSDFGLLGHPQMNSTLSKPVNMLKEKSFEEGRQEHTQNSKNRDGNIQLSPGTSQSQMIVNFPAHKEMHEYQTTVQQLQPALWKENEAQATNQTKEDKTRSSTPALSERRVKQNEQAKGHHSARQLVTSLNSFTDSSVNIKNSSGTSSSSGGKSKNCSSKKYIPKVTETLIANDGERGDQSRLQMVDCSGTDTVGSASEIQESIQSIGNT", "length": 796, "header": "tr|E1C530-1|E1C530_CHICK Isoform 1 of Centrosomal protein of 78 kDa OS=Gallus gallus OX=9031 GN=CEP78 PE=1 SV=3 CANONICAL=E1C530-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YU29-1", "url": "https://www.uniprot.org/uniprotkb/E1C530/entry#A0A8V0YU29-1", "sequence": { "sequence": "MIDSVKIRRQCMLDFYSHYEHLCAVQGSVPLKAVKTNLTQGTLDLTVDRIKAADWTPLLDAIRHDKTLTSVGIRSCHHQGLGESGAERYKTYFRRRIPAIRSKDLTGQLCKAIKGCLSISDVLKNLELQGLLLRERDLILLTKGLATTSSLESISLAHCPIGDGGLETVCQSMKNSATIRYVNFTGCSLTWRGAEHMANVLKHQAMKRHGEAWAESLRYRRPDLDYMTGLRRITFNCNMLVGDRGASAFADCLGEDLWLKALDLQHCGISNEGARSLLDALRTNTTLVVLDIRKNPLIDHVLMKNIIERVLMNGSSANSEYKWLSSPSSKDALKARPKKRTIVLGSGRKGKATIRIGLTSKKSVSPGKKTLSVKDSYSPKPLPPGTKGFLPWRTAERAKRCRGGPGDNSGELPLKIQMGIPVKVTVESASTSETEETEDLEDVIHHPDLTKSVDKVNVTKYQQFQLELEECMEKLKEERRARVKAEERIMEALHVQSVTNMILEDEGVLGSIENSFQKFHAFLDLLKDAGLGQLAVLAGIDQSDFGLLGHPQMNSTLSKPVNMLKEKSFEEGRQEHTQNSKNRDGNIQLSPGTSQSQMIVNFPAHKEMHEYQTTVQQLQPALWKENEAQATNQTKEDKTRSSTPALSERRVKQNEQAKGHHSARQLVTSLNSFTDSSVNIKNSSGTSSSSGGKSKNCSSKKYIPKVTETLIANDGERGDQSRLQMVDCSGTDTVGSASEIQESIQSIGNT", "length": 750, "header": "tr|A0A8V0YU29-1|E1C530_CHICK Computationally mapped isoform of Centrosomal protein of 78 kDa OS=Gallus gallus OX=9031 GN=CEP78 PE=1 SV=1 CANONICAL=E1C530-1" }, "locus": { "chromosome": "Z", "start_pos": 38577799, "end_pos": 38556138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038302.1", "url": "https://www.ensembl.org/id/ENSGALT00010038302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022117.1", "url": "https://www.ensembl.org/id/ENSGALP00010022117.1" } ] } }, { "isoform_ac": "A0A8V0YU35-1", "url": "https://www.uniprot.org/uniprotkb/E1C530/entry#A0A8V0YU35-1", "sequence": { "sequence": "MIDSVKIRRQCMLDFYSHYEHLCAVQGSVPLKAVKTNLTQGTLDLTVDRIKAADWTPLLDAIRHDKTLTSVGIRSCHHQGLGESGAERYKTYFRRRIPAIRSKDLTGQLCKAIKGCLSISDVLKNLELQGLLLRERDLILLTKGLATTSSLESISLAHCPIGDGGLETVCQSMKNSATIRYVNFTGCSLTWRGAEHMANVLKHQAMKRHGEAWAESLRYRRPDLDYMTGLRRITFNCNMLVGDRGASAFADCLGEDLWLKALDLQHCGISNEGARSLLDALRTNTTLVVLDIRKNPLIDHVLMKNIIERVLMNGSSANSEYKWLSSPSSKDALKARPKKRTIVLGSGRKGKATIRIGLTSKKSVSPGKKTLSVKDSYSPKPLPPGTKGFLPWRTAERAKRGGPGDNSGELPLKIQMGIPVKVTVESASTSETEETEDLEDVIHHPDLTKSVDKVNVTKYQQFQLELEECMEKLKEERRARVKAEERIMELEVENARLRNLNTSLSEALHVQSVTNMILEDEGVLGSIENSFQKFHAFLDLLKDAGLGQLAVLAGIDQSDFGLLGHPQMNSTLSKPVNMLKEKSFEEGRQEHTQNSKNRDGNIQLSPGTSQSQMIVNFPAHKEMHEYQTTVQQLQPALWKENEAQATNQTKEDKTRSSTPALSERRVKQNEQAKGHHSARQLVTSLNSFTDSSVNIKNSSGTSSSSGGKSKNCSSKKYIPKVTETLIANDGERGDQSRLQMVDCSGTDTVGSASEIQESIQSIGNT", "length": 765, "header": "tr|A0A8V0YU35-1|E1C530_CHICK Computationally mapped isoform of Centrosomal protein of 78 kDa OS=Gallus gallus OX=9031 GN=CEP78 PE=1 SV=1 CANONICAL=E1C530-1" }, "locus": { "chromosome": "Z", "start_pos": 38577799, "end_pos": 38556138, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038307.1", "url": "https://www.ensembl.org/id/ENSGALT00010038307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022122.1", "url": "https://www.ensembl.org/id/ENSGALP00010022122.1" } ] } }, { "isoform_ac": "E1C530-1", "url": "https://www.uniprot.org/uniprotkb/E1C530/entry#E1C530-1", "sequence": { "sequence": "MEIVAELISCWKKLIFFFLILQKHLSSRKMIDSVKIRRQCMLDFYSHYEHLCAVQGSVPLKAVKTNLTQGTLDLTVDRIKAADWTPLLDAIRHDKTLTSVGIRSCHHQGLGESGAERYKTYFRRRIPAIRSKDLTGQLCKAIKGCLSISDVLKNLELQGLLLRERDLILLTKGLATTSSLESISLAHCPIGDGGLETVCQSMKNSATIRYVNFTGCSLTWRGAEHMANVLKHQAMKRHGEAWAESLRYRRPDLDYMTGLRRITFNCNMLVGDRGASAFADCLGEDLWLKALDLQHCGISNEGARSLLDALRTNTTLVVLDIRKNPLIDHVLMKNIIERVLMNGSSANSEYKWLSSPSSKDALKARPKKRTIVLGSGRKGKATIRIGLTSKKSVSPGKKTLSVKDSYSPKPLPPGTKGFLPWRTAERAKRCRGGPGDNSGELPLKIQMGIPVKVTVESASTSETEETEDLEDVIHHPDLTKSVDKVNVTKYQQFQLELEECMEKLKEERRARVKAEERIMELEVENARLRNLNTSLSEALHVQSVTNMILEDEGVLGSIENSFQKFHAFLDLLKDAGLGQLAVLAGIDQSDFGLLGHPQMNSTLSKPVNMLKEKSFEEGRQEHTQNSKNRDGNIQLSPGTSQSQMIVNFPAHKEMHEYQTTVQQLQPALWKENEAQATNQTKEDKTRSSTPALSERRVKQNEQAKGHHSARQLVTSLNSFTDSSVNIKNSSGTSSSSGGKSKNCSSKKYIPKVTETLIANDGERGDQSRLQMVDCSGTDTVGSASEIQESIQSIGNT", "length": 796, "header": "tr|E1C530-1|E1C530_CHICK Isoform 1 of Centrosomal protein of 78 kDa OS=Gallus gallus OX=9031 GN=CEP78 PE=1 SV=3 CANONICAL=E1C530-1" }, "locus": { "chromosome": "Z", "start_pos": 38577799, "end_pos": 38556051, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010038298.1", "url": "https://www.ensembl.org/id/ENSGALT00010038298.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022113.1", "url": "https://www.ensembl.org/id/ENSGALP00010022113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "E1C530", "url": "https://www.uniprot.org/uniprotkb/E1C530" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 678, "end_pos": 680, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C530-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 796, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C530-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C530" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 600, "end_pos": 602 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 678, "end_pos": 680 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 742, "end_pos": 744 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIQ3-1", "uniprot_ac": "F1NIQ3", "uniprot_id": "F1NIQ3_CHICK", "mass": { "chemical_mass": 153068.0, "monoisotopic_mass": 153068.0 }, "refseq": { "ac": "NP_001012598", "name": "sister chromatid cohesion protein PDS5 homolog A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012598" }, "gene_names": [ { "name": "PDS5A", "type": "recommended", "evidence": [ { "id": "F1NIQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ] }, { "name": "PDS5A", "type": "synonym", "evidence": [ { "id": "NP_001012598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012598" } ] } ], "protein_names": [ { "name": "PDS5 cohesin associated factor A", "type": "synonym", "evidence": [ { "id": "F1NIQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3/entry#names_and_taxonomy" } ] }, { "name": "PDS5, regulator of cohesion maintenance, homolog A", "type": "synonym", "evidence": [ { "id": "NP_001012598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012598" } ] }, { "name": "sister chromatid cohesion protein PDS5 homolog A", "type": "synonym", "evidence": [ { "id": "NP_001012598", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012598" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851547.1, SRR13267659.38386.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000074.1. On Sep 23, 2021 this sequence version replaced NP_001012598.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012598" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDS5A", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3", "locus": { "chromosome": "4", "start_pos": 68669910, "end_pos": 68597590, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016242", "url": "https://www.ensembl.org/id/ENSGALG00010016242" } ] } } ], "crossref": [ { "id": "ENSGALG00000014286", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014286", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19953", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19953", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422787", "url": "https://www.ncbi.nlm.nih.gov/gene/422787", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422787", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422787", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YUY2", "url": "https://www.orthodb.org/?gene=A0A8V0YUY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWW9", "url": "https://www.orthodb.org/?gene=A0A8V0YWW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NIQ3", "url": "https://www.orthodb.org/?gene=F1NIQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12663:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12663:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2468052", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2468052", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2470946", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2470946", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001012598", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012598", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHLPELRERPVEDCAEGKFLSSGTRMDFPAAQPKPAADGKIIYYPPGVKEITDKITNDEVVKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNQKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQAFDLAKVLLKRTVQTIEPCIANFFNQVLVLGKSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAGKRDLSLVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHAEAGKDAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANSAAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRAGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMANEKLLSLLPEYVVPYMIHLLAHDPDFTKPQDVDQLRDVKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDEPKANEKLYTVCDVALCVINSKSALCNADSPKDPVLPTKFFTQPEKDFSNDRNYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRRPYIRTTGSETGSNISVNSELSSSAGNRSREQSSDISETGVSENDENPVRIISVTPAKTEPVKNKEINSDQATQGNSTERGKKRTATASGTENIHQKAEENNADETGPSLAAKTRRGRPPKPEPQGTTAKNEETNKPPVRGRKRAAASQESPGSLEAGNAKAPKQQDTAKKPAAAQRQIDLQR", "length": 1356, "header": "tr|F1NIQ3-1|F1NIQ3_CHICK Isoform 1 of PDS5 cohesin associated factor A OS=Gallus gallus OX=9031 GN=PDS5A PE=1 SV=2 CANONICAL=F1NIQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUY2-1", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3/entry#A0A8V0YUY2-1", "sequence": { "sequence": "MLHLPELRERPVEDCAEGKFLSSGTRMDFPAAQPKPAADGKIIYYPPGVKEITDKITNDEVVKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNQKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQAFDLAKVLLKRTVQTIEPCIANFFNQVLVLGKSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAGKRDLSLVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHAEAGKDAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANSAAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRAGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMANEKLLSLLPEYVVPYMIHLLAHDPDFTKPQDVDQLRDVKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDEPKANEKLYTVCDVALCVINSKSALCNADSPKDPVLPTKFFTQPEKDFSNDRNYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRRPYIRTTGSETGSNISVNSELSSSAGNRSREQSSDISETGVSENDENPVRIISVTPAKTEPVKNKEINSDQATQGNSTERGKKRTATASGTENIHQKAEENNADETGPSLAAKTRRGRPPKPEPQGTTAKNEETNKPPVRGRKRAAASQESPGSLEAGNAKAPKQQDTAKKPAAAQRQIDLQR", "length": 1333, "header": "tr|A0A8V0YUY2-1|F1NIQ3_CHICK Computationally mapped isoform of PDS5 cohesin associated factor A OS=Gallus gallus OX=9031 GN=PDS5A PE=1 SV=1 CANONICAL=F1NIQ3-1" }, "locus": { "chromosome": "4", "start_pos": 68668698, "end_pos": 68597788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039064.1", "url": "https://www.ensembl.org/id/ENSGALT00010039064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022563.1", "url": "https://www.ensembl.org/id/ENSGALP00010022563.1" } ] } }, { "isoform_ac": "A0A8V0YWW9-1", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3/entry#A0A8V0YWW9-1", "sequence": { "sequence": "MISGKQADMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNQKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQAFDLAKVLLKRTVQTIEPCIANFFNQVLVLGKSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAGKRDLSLVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHAEAGKDAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANSAAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRAGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMANEKLLSLLPEYVVPYMIHLLAHDPDFTKPQDVDQLRDVKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDEPKANEKLYTVCDVALCVINSKSALCNADSPKDPVLPTKFFTQPEKDFSNDRNYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRRPYIRTTGSETGSNISVNSELSSSAGNRSREQSSDISETGVSENDENPVRIISVTPAKTEPVKNKEINSDQATQGNSTERGKKRTATASGTENIHQKAEENNADETGPSLAAKTRRGRPPKPEPQGTTAKNEETNKPPVRGRKRAAASQESPGSLEAGNAKAPKQQDTAKKPAAAQRQIDLQR", "length": 1298, "header": "tr|A0A8V0YWW9-1|F1NIQ3_CHICK Computationally mapped isoform of PDS5 cohesin associated factor A OS=Gallus gallus OX=9031 GN=PDS5A PE=1 SV=1 CANONICAL=F1NIQ3-1" }, "locus": { "chromosome": "4", "start_pos": 68668698, "end_pos": 68624620, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039035.1", "url": "https://www.ensembl.org/id/ENSGALT00010039035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022544.1", "url": "https://www.ensembl.org/id/ENSGALP00010022544.1" } ] } }, { "isoform_ac": "F1NIQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3/entry#F1NIQ3-1", "sequence": { "sequence": "MLHLPELRERPVEDCAEGKFLSSGTRMDFPAAQPKPAADGKIIYYPPGVKEITDKITNDEVVKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNQKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQAFDLAKVLLKRTVQTIEPCIANFFNQVLVLGKSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAGKRDLSLVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHAEAGKDAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANSAAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADVCVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRAGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFSNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMANEKLLSLLPEYVVPYMIHLLAHDPDFTKPQDVDQLRDVKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDEPKANEKLYTVCDVALCVINSKSALCNADSPKDPVLPTKFFTQPEKDFSNDRNYISEETRVLLLTGKPKPTGVLGTVNKPLSATGRRPYIRTTGSETGSNISVNSELSSSAGNRSREQSSDISETGVSENDENPVRIISVTPAKTEPVKNKEINSDQATQGNSTERGKKRTATASGTENIHQKAEENNADETGPSLAAKTRRGRPPKPEPQGTTAKNEETNKPPVRGRKRAAASQESPGSLEAGNAKAPKQQDTAKKPAAAQRQIDLQR", "length": 1356, "header": "tr|F1NIQ3-1|F1NIQ3_CHICK Isoform 1 of PDS5 cohesin associated factor A OS=Gallus gallus OX=9031 GN=PDS5A PE=1 SV=2 CANONICAL=F1NIQ3-1" }, "locus": { "chromosome": "4", "start_pos": 68668698, "end_pos": 68597788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039054.1", "url": "https://www.ensembl.org/id/ENSGALT00010039054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010022557.1", "url": "https://www.ensembl.org/id/ENSGALP00010022557.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1228, "start_aa": "Thr", "end_pos": 1228, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1228", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422787", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422787", "resource": "KEGG Pathway" }, { "id": "R-GGA-2467813", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "resource": "Reactome", "description": "Separation of Sister Chromatids" }, { "id": "R-GGA-2468052", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2468052", "resource": "Reactome", "description": "Establishment of Sister Chromatid Cohesion" }, { "id": "R-GGA-2470946", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2470946", "resource": "Reactome", "description": "Cohesin Loading onto Chromatin" }, { "id": "R-GGA-2500257", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "resource": "Reactome", "description": "Resolution of Sister Chromatid Cohesion" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "pmid": "" }, { "name": "mitotic sister chromatid cohesion", "id": "GO:0007064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007064", "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "pmid": "" }, { "name": "negative regulation of DNA replication", "id": "GO:0008156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008156", "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cohesin unloader activity", "id": "GO:0140670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140670", "evidence": [ { "database": "UniProtKB", "id": "F1NIQ3", "url": "https://www.uniprot.org/uniprotkb/F1NIQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1187, "end_pos": 1189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1200, "end_pos": 1202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1249, "end_pos": 1251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 995, "end_pos": 997, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1228 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 1187, "end_pos": 1189 }, { "start_pos": 1200, "end_pos": 1202 }, { "start_pos": 1249, "end_pos": 1251 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 656, "end_pos": 658 }, { "start_pos": 872, "end_pos": 874 }, { "start_pos": 878, "end_pos": 880 }, { "start_pos": 995, "end_pos": 997 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C397-1", "uniprot_ac": "E1C397", "uniprot_id": "E1C397_CHICK", "mass": { "chemical_mass": 55730.0, "monoisotopic_mass": 55730.0 }, "refseq": { "ac": "XP_422716", "name": "protein MB21D2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422716" }, "gene_names": [ { "name": "MB21D2", "type": "recommended", "evidence": [ { "id": "E1C397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C397" } ] }, { "name": "MB21D2", "type": "synonym", "evidence": [ { "id": "XP_422716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422716" } ] } ], "protein_names": [ { "name": "Nucleotidyltransferase MB21D2", "type": "recommended", "evidence": [ { "id": "E1C397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C397/entry#names_and_taxonomy" } ] }, { "name": "Mab-21 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "E1C397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C397/entry#names_and_taxonomy" } ] }, { "name": "protein MB21D2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422716" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_422716.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422716" } ] }, { "annotation": "Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YVB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB7#function" }, { "database": "UniProtKB", "id": "ARBA00054069", "url": "https://www.uniprot.org/uniprotkb/ARBA00054069#function" }, { "database": "UniProtKB", "id": "E1C397", "url": "https://www.uniprot.org/uniprotkb/E1C397#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C397", "url": "https://www.uniprot.org/uniprotkb/E1C397" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MB21D2", "url": "https://www.uniprot.org/uniprotkb/E1C397", "locus": { "chromosome": "9", "start_pos": 13015136, "end_pos": 12964435, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017587", "url": "https://www.ensembl.org/id/ENSGALG00010017587" } ] } } ], "crossref": [ { "id": "E1C397", "url": "https://alphafold.ebi.ac.uk/entry/E1C397", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007218", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007218", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424905", "url": "https://www.ncbi.nlm.nih.gov/gene/424905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424905", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424905", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTRHDQR", "url": "https://omabrowser.org/oma/group/FTRHDQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YVB7", "url": "https://www.orthodb.org/?gene=A0A8V0YVB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C397", "url": "https://www.orthodb.org/?gene=E1C397", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C397", "url": "https://www.uniprot.org/uniprotkb/E1C397", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C397-1", "url": "https://www.uniprot.org/uniprotkb/E1C397-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMAAPLASKAGSAGTNSKPPFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDIDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLELQRRGSTTSIPSPQSDGGDTNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491, "header": "tr|E1C397-1|E1C397_CHICK Isoform 1 of Nucleotidyltransferase MB21D2 OS=Gallus gallus OX=9031 GN=MB21D2 PE=3 SV=3 CANONICAL=E1C397-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YVB7-1", "url": "https://www.uniprot.org/uniprotkb/E1C397/entry#A0A8V0YVB7-1", "sequence": { "sequence": "MMCFVVWLCKGSKEPCRASNSQSCMVQKLDQKLPVANEYLLLSGGVREGVVDIDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLELQRRGSTTSIPSPQSDGGDTNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 444, "header": "tr|A0A8V0YVB7-1|E1C397_CHICK Computationally mapped isoform of Nucleotidyltransferase MB21D2 OS=Gallus gallus OX=9031 GN=MB21D2 PE=3 SV=1 CANONICAL=E1C397-1" }, "locus": { "chromosome": "9", "start_pos": 13012713, "end_pos": 12978334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042513.1", "url": "https://www.ensembl.org/id/ENSGALT00010042513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025003.1", "url": "https://www.ensembl.org/id/ENSGALP00010025003.1" } ] } }, { "isoform_ac": "E1C397-1", "url": "https://www.uniprot.org/uniprotkb/E1C397/entry#E1C397-1", "sequence": { "sequence": "MKMAAPLASKAGSAGTNSKPPFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDIDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLELQRRGSTTSIPSPQSDGGDTNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491, "header": "tr|E1C397-1|E1C397_CHICK Isoform 1 of Nucleotidyltransferase MB21D2 OS=Gallus gallus OX=9031 GN=MB21D2 PE=3 SV=3 CANONICAL=E1C397-1" }, "locus": { "chromosome": "9", "start_pos": 13012713, "end_pos": 12964642, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042514.1", "url": "https://www.ensembl.org/id/ENSGALT00010042514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025004.1", "url": "https://www.ensembl.org/id/ENSGALP00010025004.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424905", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424905", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACS3-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "Mb21d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMAAPTASKAASMGCNNKPAFPELDFRSGARVEELNKLIQEFTRHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPVSYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491 }, "evidence": [ { "id": "E1C397", "url": "https://omabrowser.org/oma/group/E1C397/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B9A3-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "MB21D2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKMAAPTASKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLELQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491 }, "evidence": [ { "id": "E1C397", "url": "https://omabrowser.org/oma/group/E1C397/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7FBQ4-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "LOC556707", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAPALSSRAASAGNSPTATPSSSKPVPQAPELDFRSGTRIEELNRLIGEFSKHEQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDMDLDELTVYARGADYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTINKWKDCCTMIDHANGATNYFFSPTLVADWFYESISMVLAEIQKKPQRGVPRVEKVERNATVISIILGVGGSRMLYDVVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLLPACSSTGQKENEWRLSFARSEVQLKKCISASLMQAYQACKALIIKLLSRPKAISPYHLRSLMLWSCDRLPHTYLAQEDYAAHFLLGLIDDLQHCLVNKTCPNYFIPQCNMLEHLSDDMAMLHARKLSSVRSDPAEHLRSAIEHAKAASRLTVELQWRSGSSNLPSPLSETGADQQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 499 }, "evidence": [ { "id": "E1C397", "url": "https://omabrowser.org/oma/group/E1C397/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SFH0-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "MB21D2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKMAAPTASKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLELQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491 }, "evidence": [ { "id": "E1C397", "url": "https://omabrowser.org/oma/group/E1C397/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8C525-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "Mb21d2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQTPMTGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKGCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPASYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 428 }, "evidence": [ { "id": "E1C397", "url": "https://omabrowser.org/oma/group/E1C397/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYB1-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "MB21D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMAAPTANKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLELQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491 }, "evidence": [ { "id": "E1C397", "url": "https://omabrowser.org/oma/group/E1C397/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "E1C397", "url": "https://www.uniprot.org/uniprotkb/E1C397" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "E1C397", "url": "https://www.uniprot.org/uniprotkb/E1C397" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C397-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 491, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C397-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C397" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C397" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 325, "end_pos": 400, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1C397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C397" }, { "id": "PF03281", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like nucleotidyltransferase", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 298, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C6C2-1", "uniprot_ac": "E1C6C2", "uniprot_id": "E1C6C2_CHICK", "mass": { "chemical_mass": 14002.0, "monoisotopic_mass": 14002.0 }, "refseq": { "ac": "NP_001264036", "name": "RNA guanine-N7 methyltransferase activating subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" }, "gene_names": [ { "name": "FAM103A1", "type": "recommended", "evidence": [ { "id": "E1C6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6C2" } ] }, { "name": "FAM103A1", "type": "synonym", "evidence": [ { "id": "NP_001264036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" } ] }, { "name": "RAMAC", "type": "synonym", "evidence": [ { "id": "NP_001264036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 103 member A1", "type": "synonym", "evidence": [ { "id": "E1C6C2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6C2/entry#names_and_taxonomy" } ] }, { "name": "RNA guanine-7 methyltransferase activating subunit", "type": "synonym", "evidence": [ { "id": "NP_001264036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" } ] }, { "name": "RNA guanine-N7 methyltransferase activating subunit", "type": "synonym", "evidence": [ { "id": "NP_001264036", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01010914.1, SRR12888510.286644.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Mar 10, 2013 this sequence version replaced XP_413837.3. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264036", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" } ] }, { "annotation": "In humans FAM103A1, also known as RNA guanine-7 methyltransferase Activating Mini protein or RAM, has been shown to be required for efficient cap methylation of mRNA in vitro and in vivo and is indirectly required to maintain mRNA expression levels for mRNA translation and for cell viability.", "evidence": [ { "database": "RefSeq", "id": "NP_001264036", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" }, { "database": "PubMed", "id": "22099306", "url": "https://glygen.org/publication/PubMed/22099306" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6C2", "url": "https://www.uniprot.org/uniprotkb/E1C6C2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM103A1", "url": "https://www.uniprot.org/uniprotkb/E1C6C2", "locus": { "chromosome": "10", "start_pos": 11200401, "end_pos": 11188524, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016607", "url": "https://www.ensembl.org/id/ENSGALG00010016607" } ] } } ], "crossref": [ { "id": "E1C6C2", "url": "https://alphafold.ebi.ac.uk/entry/E1C6C2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006010", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006010", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415459", "url": "https://www.ncbi.nlm.nih.gov/gene/415459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415459", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415459", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPIIEEW", "url": "https://omabrowser.org/oma/group/PPIIEEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWP4", "url": "https://www.orthodb.org/?gene=A0A8V0YWP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX33", "url": "https://www.orthodb.org/?gene=A0A8V0YX33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6C2", "url": "https://www.orthodb.org/?gene=E1C6C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48168:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48168:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264036", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YWP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6C2", "url": "https://www.uniprot.org/uniprotkb/E1C6C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6C2-1", "url": "https://www.uniprot.org/uniprotkb/E1C6C2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLVDIPVDYEKMFAHRFTADDKEYQEYLKRPADPPPIVEEWRNRSGGNQRNRDRFQDGRYFRGDRYNWQGDHRSNQRPDRGWGNNYQQHRQGQSYYGQYGYNSYNPGPRYHPY", "length": 115, "header": "tr|E1C6C2-1|E1C6C2_CHICK Isoform 1 of Family with sequence similarity 103 member A1 OS=Gallus gallus OX=9031 GN=FAM103A1 PE=1 SV=3 CANONICAL=E1C6C2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YWP4-1", "url": "https://www.uniprot.org/uniprotkb/E1C6C2/entry#A0A8V0YWP4-1", "sequence": { "sequence": "MGKKWQQHMGVVKRETPDWKEKKRAVPWKGSRKENCLRNPGSKMEKELLLRWVRMASLVDIPVDYEKMFAHRFTADDKEYQEYLKRPADPPPIVEEWRNRSGGNQRNRDRFQDGRYFRGDRYNWQGDHRSNQRPDRGWGNNYQQHRQGQSYYGQYGYNSYNPGPRYHPY", "length": 169, "header": "tr|A0A8V0YWP4-1|E1C6C2_CHICK Computationally mapped isoform of Family with sequence similarity 103 member A1 OS=Gallus gallus OX=9031 GN=FAM103A1 PE=1 SV=1 CANONICAL=E1C6C2-1" }, "locus": { "chromosome": "10", "start_pos": 11196527, "end_pos": 11188537, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040046.1", "url": "https://www.ensembl.org/id/ENSGALT00010040046.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023200.1", "url": "https://www.ensembl.org/id/ENSGALP00010023200.1" } ] } }, { "isoform_ac": "A0A8V0YX33-1", "url": "https://www.uniprot.org/uniprotkb/E1C6C2/entry#A0A8V0YX33-1", "sequence": { "sequence": "MAVHPAARKASPRFAHTEVSASQRTCTHTASSTTAVPRPQNRAPTKPAKERTADILYAIHTSARSAPNSGLAEPNPQATAARGAPALRHPALSRHRKRRGAHRKSRALRAAAAGGAGMASLVDIPVDYEKMFAHRFTADDKEYQEYLKRPADPPPIVEEWRNRSGGNQRNRDRFQDGRYFRGDRYNWQGDHRSNQRPDRGWGNNYQQHRQGQSYYGQYGYNSYNPGPRYHPY", "length": 232, "header": "tr|A0A8V0YX33-1|E1C6C2_CHICK Computationally mapped isoform of Family with sequence similarity 103 member A1 OS=Gallus gallus OX=9031 GN=FAM103A1 PE=1 SV=1 CANONICAL=E1C6C2-1" }, "locus": { "chromosome": "10", "start_pos": 11196527, "end_pos": 11194019, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040041.1", "url": "https://www.ensembl.org/id/ENSGALT00010040041.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023197.1", "url": "https://www.ensembl.org/id/ENSGALP00010023197.1" } ] } }, { "isoform_ac": "E1C6C2-1", "url": "https://www.uniprot.org/uniprotkb/E1C6C2/entry#E1C6C2-1", "sequence": { "sequence": "MASLVDIPVDYEKMFAHRFTADDKEYQEYLKRPADPPPIVEEWRNRSGGNQRNRDRFQDGRYFRGDRYNWQGDHRSNQRPDRGWGNNYQQHRQGQSYYGQYGYNSYNPGPRYHPY", "length": 115, "header": "tr|E1C6C2-1|E1C6C2_CHICK Isoform 1 of Family with sequence similarity 103 member A1 OS=Gallus gallus OX=9031 GN=FAM103A1 PE=1 SV=3 CANONICAL=E1C6C2-1" }, "locus": { "chromosome": "10", "start_pos": 11196527, "end_pos": 11195475, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040032.1", "url": "https://www.ensembl.org/id/ENSGALT00010040032.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023190.1", "url": "https://www.ensembl.org/id/ENSGALP00010023190.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RAM/Fam103a1 is required for mRNA cap methylation.", "journal": "Molecular cell", "date": "2011", "authors": "Gonatopoulos-Pournatzis T, Dunn S, Bounds R, Cowling VH", "evidence": [ { "database": "RefSeq", "id": "NP_001264036", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264036" } ], "reference": [ { "type": "PubMed", "id": "22099306", "url": "https://glygen.org/publication/PubMed/22099306" } ] } ], "pathway": [ { "id": "gga:415459", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415459", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3B3IU46-1", "protein_name": "RNA guanine-N7 methyltransferase-activating subunit-like protein", "gene_name": "RAMACL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDTAEAVPNFEEMFASRFTENDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNRLQDNRQFRGRDNRWGWPSDNRSNQWHGRSWGNNYPQHRQEPYYPQQYGHYGYNQRPPYGYY", "length": 118 }, "evidence": [ { "id": "E1C6C2", "url": "https://omabrowser.org/oma/group/E1C6C2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1UNN8-1", "protein_name": "RNA guanine-7 methyltransferase activating subunit", "gene_name": "RAMAC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTDNSEAVPNFEEMFASRFTEDDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNRLQDNRQFRGRDSRRGWPSDSRSNQWPGRSWGNSYPQHRQEPYYPHQYGNYGHNQRPPYGYY", "length": 118 }, "evidence": [ { "id": "E1C6C2", "url": "https://omabrowser.org/oma/group/E1C6C2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4AD33-1", "protein_name": "RNA guanine-7 methyltransferase activating subunit", "gene_name": "Ramac", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDTSEAIPIFEEMFANRFTQDDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNWLQDNRQFRGRDNRRGWPSDNRSNQWHGRSWGNNNYPQQRPEPYYQPNCPQYGHNQRPPYGYY", "length": 119 }, "evidence": [ { "id": "E1C6C2", "url": "https://omabrowser.org/oma/group/E1C6C2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IA04-1", "protein_name": "RNA guanine-N7 methyltransferase activating subunit", "gene_name": "Ramac", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDTSEVTPDFEEMFASRFTQDDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNWLQDNRQFRGRDNRRGWPSDNRANQWHGRSWGNNYPQQRQEPYYQQQYGQYGHNPRPPYGYY", "length": 118 }, "evidence": [ { "id": "E1C6C2", "url": "https://omabrowser.org/oma/group/E1C6C2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9CQY2-1", "protein_name": "RNA guanine-N7 methyltransferase activating subunit", "gene_name": "Ramac", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDTSEEIPNFEEMFASRFTKDDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNWLQDNRQFRGRDNRRGWPSDNRSNQWHGRSWGNNNYPQQRPEPYYQQQYTQYGHNQRPPYGYY", "length": 119 }, "evidence": [ { "id": "E1C6C2", "url": "https://omabrowser.org/oma/group/E1C6C2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E1C6C2", "url": "https://www.uniprot.org/uniprotkb/E1C6C2" } ], "pmid": "" }, { "name": "enzyme activator activity", "id": "GO:0008047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008047", "evidence": [ { "database": "UniProtKB", "id": "E1C6C2", "url": "https://www.uniprot.org/uniprotkb/E1C6C2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA 5'-cap (guanine-N7)-methylation", "id": "GO:0106005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106005", "evidence": [ { "database": "UniProtKB", "id": "E1C6C2", "url": "https://www.uniprot.org/uniprotkb/E1C6C2" } ], "pmid": "" }, { "name": "7-methylguanosine mRNA capping", "id": "GO:0006370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006370", "evidence": [ { "database": "UniProtKB", "id": "E1C6C2", "url": "https://www.uniprot.org/uniprotkb/E1C6C2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mRNA capping enzyme complex", "id": "GO:0031533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031533", "evidence": [ { "database": "UniProtKB", "id": "E1C6C2", "url": "https://www.uniprot.org/uniprotkb/E1C6C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": 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genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641283" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1T6", "url": "https://www.uniprot.org/uniprotkb/E1C1T6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCUN1D4", "url": "https://www.uniprot.org/uniprotkb/E1C1T6", "locus": { "chromosome": "4", "start_pos": 65700270, "end_pos": 65737720, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016560", "url": "https://www.ensembl.org/id/ENSGALG00010016560" } ] } } ], "crossref": [ { "id": "E1C1T6", "url": "https://alphafold.ebi.ac.uk/entry/E1C1T6", "database": "AlphaFoldDB", 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"categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWT4", "url": "https://www.orthodb.org/?gene=A0A8V0YWT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3C5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3D1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1T6", "url": "https://www.orthodb.org/?gene=E1C1T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12281:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12281:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003641283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641283", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3ADG9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ADG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3ADG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3ADG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3C5", "url": 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"MHSDAAAVNFQLNSHLSTLANIHKIYHTLNRLNLTEDVGQDDHQTGSLRSCSSSDCFSKVMPPRKKRRPAAGDDLSAKKSRHDGMYRKYDSTRIKAEEEVFSSKRCLEWFYEYAGTDDIVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRNSLDCLRSLLNEPTNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKTWSLFPVFHQFLEQSKYKVINKDQWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEWYKGKQMT", "length": 292, "header": "tr|E1C1T6-1|E1C1T6_CHICK Isoform 1 of Defective in cullin neddylation 1 domain containing 4 OS=Gallus gallus OX=9031 GN=DCUN1D4 PE=4 SV=4 CANONICAL=E1C1T6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3ADG9-1", "url": "https://www.uniprot.org/uniprotkb/E1C1T6/entry#A0A3Q3ADG9-1", "sequence": { "sequence": "MHSDAAAVNFQLNSHLSTLANIHKIYHTLNRLNLTEDVGQDDHQTGERLSKIRRIGSLRSCSSSDCFSKVMPPRKKRRPAAGDDLSAKKSRHDGMYRKYDSTRIKAEEEVFSSKRCLEWFYEYAGENFKYGKKNLMTVKKTKRK", "length": 144, "header": "tr|A0A3Q3ADG9-1|A0A3Q3ADG9_CHICK Computationally mapped isoform of Defective in cullin neddylation 1 domain containing 4 OS=Gallus gallus OX=9031 GN=DCUN1D4 PE=4 SV=1 CANONICAL=E1C1T6-1" }, "locus": { "chromosome": "4", "start_pos": 65737565, "end_pos": 65711228, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039885.1", "url": "https://www.ensembl.org/id/ENSGALT00010039885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023087.1", "url": "https://www.ensembl.org/id/ENSGALP00010023087.1" } ] } }, { "isoform_ac": "A0A8V0YWT4-1", "url": "https://www.uniprot.org/uniprotkb/E1C1T6/entry#A0A8V0YWT4-1", "sequence": { "sequence": "MHSDAAAVNFQLNSHLSTLANIHKIYHTLNRLNLTEDVGQDDHQTGSLRSCSSSDCFSKVMPPRKKRRPAAGDDLSAKKSRHDGMYRKYDSTRIKAEEEVFSSKRCLEWFYEYAGTDDIVGPEGMEKFCEDIGVEPENKKIKSLKTGDDIFSETTLEI", "length": 158, "header": "tr|A0A8V0YWT4-1|E1C1T6_CHICK Computationally mapped isoform of Defective in cullin neddylation 1 domain containing 4 OS=Gallus gallus OX=9031 GN=DCUN1D4 PE=4 SV=1 CANONICAL=E1C1T6-1" }, "locus": { "chromosome": "4", "start_pos": 65737565, "end_pos": 65709159, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039894.1", "url": "https://www.ensembl.org/id/ENSGALT00010039894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023093.1", "url": "https://www.ensembl.org/id/ENSGALP00010023093.1" } ] } }, { "isoform_ac": "A0A8V0Z3C5-1", "url": "https://www.uniprot.org/uniprotkb/E1C1T6/entry#A0A8V0Z3C5-1", "sequence": { "sequence": "MPLLSNLTEDVGQDDHQTGSLRSCSSSDCFSKVMPPRKKRRPAAGDDLSAKKSRHDGMYRKYDSTRIKAEEEVFSSKRCLEWFYEYAGTDDIVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQCDTTEKLRNSLDCLRSLLNEPTNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKTWSLFPVFHQFLEQSKYKVINKDQWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEWYKGKQMT", "length": 265, "header": "tr|A0A8V0Z3C5-1|A0A8V0Z3C5_CHICK Computationally mapped isoform of DCN1-like protein OS=Gallus gallus OX=9031 GN=DCUN1D4 PE=4 SV=1 CANONICAL=E1C1T6-1" }, "locus": { "chromosome": "4", "start_pos": 65737555, "end_pos": 65703795, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039903.1", "url": 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"https://www.ensembl.org/id/ENSGALT00010039912.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023109.1", "url": "https://www.ensembl.org/id/ENSGALP00010023109.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422762", "resource": "KEGG Pathway" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C1T6", "url": "https://www.uniprot.org/uniprotkb/E1C1T6" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C6M2-1", "uniprot_ac": "E1C6M2", "uniprot_id": "E1C6M2_CHICK", "mass": { "chemical_mass": 77691.0, "monoisotopic_mass": 77691.0 }, "refseq": { "ac": "XP_001234652", "name": "FAD-dependent oxidoreductase domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234652" }, "gene_names": [ { "name": "FOXRED2", "type": "recommended", "evidence": [ { "id": "E1C6M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6M2" } ] }, { "name": "FOXRED2", "type": "synonym", "evidence": [ { "id": "XP_001234652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234652" } ] } ], "protein_names": [ { "name": "FAD-dependent oxidoreductase domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "E1C6M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6M2/entry#names_and_taxonomy" } ] }, { "name": "FAD-dependent oxidoreductase domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_001234652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234652" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234652" } ] }, { "annotation": "Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YX17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX17#function" }, { "database": "UniProtKB", "id": "ARBA00056122", "url": "https://www.uniprot.org/uniprotkb/ARBA00056122#function" }, { "database": "UniProtKB", "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FOXRED2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2", "locus": { "chromosome": "1", "start_pos": 51777146, "end_pos": 51758933, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014936", "url": "https://www.ensembl.org/id/ENSGALG00010014936" } ] } } ], "crossref": [ { "id": "E1C6M2", "url": "https://alphafold.ebi.ac.uk/entry/E1C6M2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012530", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012530", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418054", "url": "https://www.ncbi.nlm.nih.gov/gene/418054", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418054", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418054", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGQAYQC", "url": "https://omabrowser.org/oma/group/KGQAYQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX17", "url": "https://www.orthodb.org/?gene=A0A8V0YX17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6M2", "url": "https://www.orthodb.org/?gene=E1C6M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43539", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43539", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43539:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43539:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001234652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234652", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YX17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6M2-1", "url": "https://www.uniprot.org/uniprotkb/E1C6M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGLFLRLVLSALCAAGAAAFLYHDYCVLGAGPAGLQAAYFLQRAGRDYVVFERSHAPGSFFAIYPRHRKLISINKRHTGKSNSEFNLRHDWNSLLSHEPRLLFRRYSRQFFPHADAMVRYLEDFAAMLGLRIRYDTAIVHVTLEKDPRAWNGHYFVLSDQNRQSYKCSCLLVATGTWVPNVVNFPGSEYVEGYETVSTNPEDFAGQTVLILGRGNSAFETAENILGVTNFIHMVSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLEGDLEDLAIVKDKKGKLHITLRFYLENRNTSAGIDGITLPQDELDNFATRAPYDRVIRCLGWKFDFSIYNRSLRMMPGRGNKSKYPQIKPSYESRGTRGLFVLGTASHSVDFRKSAGGFIHGFRYTTRAVHRLLENRHHGVPWPSAVYPITQLTNSIIKRVNEASGLYQMFSVLADIILLRENATAFEYLEEYPVGILAELETQTGRKAPAGLFVVIMEYGRNFSGDDKDVFYYNRAVGEAQHAWQSNFLHPVIYYYKRLPTEREMRLHPPDWPLPRPDAIHHIVEDFLTDWTAPNAHILPLRRFLENCLSTDLRNFFAESCFLFALTRQKLPPFCQQGYARMQGLTGSERLRRHAVEAGLLEDYAVTDFSGDKLPDSRQGSHDQLLRDHVIPLRPLHHLVNAKDEF", "length": 680, "header": "tr|E1C6M2-1|E1C6M2_CHICK Isoform 1 of FAD-dependent oxidoreductase domain-containing protein 2 OS=Gallus gallus OX=9031 GN=FOXRED2 PE=3 SV=3 CANONICAL=E1C6M2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YX17-1", "url": "https://www.uniprot.org/uniprotkb/E1C6M2/entry#A0A8V0YX17-1", "sequence": { "sequence": "MARGLFLRLVLSALCAAGAAAFLYHDYCVLGAGPAGLQAAYFLQRAGRDYVVFERSHAPGSFFAIYPRHRKLISINKRHTGKSNSEFNLRHDWNSLLSHEPRLLFRRYSRQFFPHADAMVRYLEDFAAMLGLRIRYDTAIVHVTLEKDPRAWNGHYFVLSDQNRQSYKCSCLLVATGTWVPNVVNFPGSEYVEGYETVSTNPEDFAGQTVLILGRGNSAFETAENILGVTNFIHMVSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLEGDLEDLAIVKDKKGKLHITLRFYLENRNTSAGIDGITLPQDELDNFATRAPYDRVIRCLGWKFDFSIYNRMMPGRGNKSKYPQIKPSYESRGTRGLFVLGTASHSVDFRKSAGGFIHGFRYTTRAVHRLLENRHHGVPWPSAVYPITQLTNSIIKRVNEASGLYQMFSVLADIILLRENATAFEYLEEYPVGILAELETQTGRKAPAGLFVVIMEYGRNFSGDDKDVFYYNRAVGEAQHAWQSNFLHPVIYYYKRLPTEREMRLHPPDWPLPRPDAIHHIVEDFLTDWTAPNAHILPLRRFLENCLSTDLRNFFAESCFLFALTRQKLPPFCQQGYARMQGLTGSERLRRHAVEAGLLEDYAVTDFSGDKLPDSRQGSHDQLLRDHVIPLRPLHHLVNAKDEF", "length": 677, "header": "tr|A0A8V0YX17-1|E1C6M2_CHICK Computationally mapped isoform of FAD-dependent oxidoreductase domain-containing protein 2 OS=Gallus gallus OX=9031 GN=FOXRED2 PE=3 SV=1 CANONICAL=E1C6M2-1" }, "locus": { "chromosome": "1", "start_pos": 51767353, "end_pos": 51759311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035919.1", "url": "https://www.ensembl.org/id/ENSGALT00010035919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020842.1", "url": "https://www.ensembl.org/id/ENSGALP00010020842.1" } ] } }, { "isoform_ac": "E1C6M2-1", "url": "https://www.uniprot.org/uniprotkb/E1C6M2/entry#E1C6M2-1", "sequence": { "sequence": "MARGLFLRLVLSALCAAGAAAFLYHDYCVLGAGPAGLQAAYFLQRAGRDYVVFERSHAPGSFFAIYPRHRKLISINKRHTGKSNSEFNLRHDWNSLLSHEPRLLFRRYSRQFFPHADAMVRYLEDFAAMLGLRIRYDTAIVHVTLEKDPRAWNGHYFVLSDQNRQSYKCSCLLVATGTWVPNVVNFPGSEYVEGYETVSTNPEDFAGQTVLILGRGNSAFETAENILGVTNFIHMVSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLEGDLEDLAIVKDKKGKLHITLRFYLENRNTSAGIDGITLPQDELDNFATRAPYDRVIRCLGWKFDFSIYNRSLRMMPGRGNKSKYPQIKPSYESRGTRGLFVLGTASHSVDFRKSAGGFIHGFRYTTRAVHRLLENRHHGVPWPSAVYPITQLTNSIIKRVNEASGLYQMFSVLADIILLRENATAFEYLEEYPVGILAELETQTGRKAPAGLFVVIMEYGRNFSGDDKDVFYYNRAVGEAQHAWQSNFLHPVIYYYKRLPTEREMRLHPPDWPLPRPDAIHHIVEDFLTDWTAPNAHILPLRRFLENCLSTDLRNFFAESCFLFALTRQKLPPFCQQGYARMQGLTGSERLRRHAVEAGLLEDYAVTDFSGDKLPDSRQGSHDQLLRDHVIPLRPLHHLVNAKDEF", "length": 680, "header": "tr|E1C6M2-1|E1C6M2_CHICK Isoform 1 of FAD-dependent oxidoreductase domain-containing protein 2 OS=Gallus gallus OX=9031 GN=FOXRED2 PE=3 SV=3 CANONICAL=E1C6M2-1" }, "locus": { "chromosome": "1", "start_pos": 51767353, "end_pos": 51759311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035924.1", "url": "https://www.ensembl.org/id/ENSGALT00010035924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020846.1", "url": "https://www.ensembl.org/id/ENSGALP00010020846.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418054", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418054", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480K665-1", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "gene_name": "FOXRED2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLSAAAPLWGPLGLLLAIALHPALSVSPASEPAHRDYCVLGAGPAGLQMAYFLQRAGRDYTVFERAARPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPQLLFRHYSSAYFPDASDMVRYLGDFADRLGLRVRYNTTIAHVTLNKDGQAWNGHYFILTDQKGQTFQCSVLLVATGLSVPNQVDFPGAEYMDGYESVSVDPKDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLANLAIVKDHKGKFHITLKLYLEVGNHSADAIPLPEDESDNFAMRVPYDRVIRCLGWNFDFSIFSKSLRLSSGGDFSKKYPLVRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTARAVHRLLEQRHHGVAWPATEHPVTQLASAIIRRINEASGLYQMFGVLADVVLMKENATAFEYLEEFPMQMLAQLETITGRQARHGLFVVNMEYGKNFSGPDKDVFYYDRSVGYTEDAWLSNFLHPVIYYYRHLPTEQEVRFRPADWPLPRPTAIHHVVEDFLTDWTAPVGHILPLRRFLENCLDTDLRNFYAESCFLFALTRQKLPPFCQQGYLRTQGLVGTESLRRHGVESGLLQDYAAEGWPWQDSSQQPDDHGPGGYTLAPGPPVQALDSNKEEL", "length": 687 }, "evidence": [ { "id": "E1C6M2", "url": "https://omabrowser.org/oma/group/E1C6M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LPK0-1", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "gene_name": "Foxred2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSWVPGFSPGPAPDPWEAQALGFSFLGKAGCHQLPTTRCEASPLLCRRMGPSGLLVALALHLAVCSRPHRDYCVLGAGPAGLQMAALLHRAGRDYEVFERESAPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSDDPHLLFRHYSQAYFPDASDMVRYLGDFAQRLGLRVLYNTNITHVTLDKDPQAWNGHYFILRDQKGQVYQCSVLLVATGLAVPKLVDFPGSEYVEGYESVSVDPEDFVGQNVLILGHGNSAFETAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSLDGLLESDLEYLALVKDSKGKFHITLKFLLENSSNQSADSIPLPQDDNDNFAMRVAYDRVIRCLGWKFDFSIFNQSLRLSSGTEFSKKYPLIKASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHGITWPSTQYPITQLTSSIIRRVNEASGLYQMFSVLADIILLKENATAFEYLEEFPIQMLAQLEMLTGRTARHGIFVINMEYGKNFSGPEKDVFYYDRSVAHIEDAWMSNFLHPVIYYYRHLPTEQDMRFRPAQWPLPRPVAIHHIVEDFLTDWTAPVGHILPLRRFLENCLDTDLRSFYAESCFLFTLTRQKLPPFCQQGYLRMQGLSSTKSLRQHGVESRLLQDYTAMENSSRWLDDHSSAPGPLTQFLDSNREEL", "length": 714 }, "evidence": [ { "id": "E1C6M2", "url": "https://omabrowser.org/oma/group/E1C6M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0UXS1-1", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "gene_name": "foxred2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVIQLVFRLLCVLDLLLAVSASGLHGRNRTLSHEYCVLGAGPAGLQMGYFLSRSQRDYIILERNAGPGSFFNIYPRHRKLISINKIYTGRRNKEFNLRHDWNSLLSDRPDLLFQRISRKLYPSADDFPHYLSLFEKELGLKVKYGTDVGRIKASDFNGHQGYVLTDQNGVNYQCRVLLVSTGLWVPQEVDFRGSDLVEGYESIPTDPEEFKDQAVLILGKGNSAFETAQSILGRASRIHLYSPSPVRLAWQTHYVGDLRAVNNELLDTYQLKSLDGLVEGRLEDIAIVRRAKDRGKRRAAKKRNSTSTKRNEPLYLTLTELLDDQNDTNISNVTGQNLPGYHTDNFSLRQPYDRVIRCLGFRFNFSIFDGSARPPQSSGARGRLPGVTAWYEGRGTPNMFVLGIAAHSRDYRMSAGGFIHGFRYTVRAVHKILEQRYHNIAWPTTNIPISQLQSWILRRVNEASGTYQMFGVLGDIILLQGSHCEYLEEFPLQALPQLSALSGRSISDHGLLVLVMQYGLNHTDTLGPGRAESEWTKAWKSNFLHPVLYYYKTLPTDKDMRQRPVGWPLPRPEAVHHMVEDFLTEWDQPISHSQPLRRFLEHCLKTDLRAFYAESCFLLSLTSRNPPLFCRQGYLRKQGIMGNRHLWQHAREAGLMEDAALSEDASVPEYLNHAGAAVISTVNFDL", "length": 687 }, "evidence": [ { "id": "E1C6M2", "url": "https://omabrowser.org/oma/group/E1C6M2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BD49-1", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "gene_name": "FOXRED2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLSTVAPLWGAPGLLLTIALHLALYLRPAQAWAPVHRDYCVLGAGPAGLQMAYFLQRAGRDYMVFERAPVPGSFFTRYPRHRKLISINKRYTGKTNAEFNLRHDWNSLLSHDPRLLFRHYSDAYYPDANDMVRYLSDFAERLGLHVLYNTTIAHVTVNKDRGAWNGHYFILTDHRGQAYQCSVLLVATGLSVPNQVDFPGSEYVDGYESVSVDPKDFEGQNVLILGRGNSAFETAENIFSVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAIVKDHKGKFHITLKLFMEEFFNQSSDAIPLPQDNNDNFAMRVAYDRVIRCLGWKFDFSIFSKSLRLSSGSELSEKYPLVRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEQRHHGVAWPSTEHPITHLASAIIRRINEASGLYQMFSVLADVVLLKENATTFEYLEEFPMQMLAQLETITGKRARHGLFVINMEYGRNYSGPDKDVFFSDRSVGHMEDAWLSNFLHPVIYYYRHLPTEQEVRFRPAGWPLPRPSALHHVVEDFLTDWTAPVGHILPLRRFLENCLDTDLRSFYAESCFLFALTHQKLPPFCQQGYLRTQGLVGTESLRQHGVESGLLWDSATMGQNQGASDQRPGDHGPGGHPLAPGPPVSPFNSNKEEL", "length": 690 }, "evidence": [ { "id": "E1C6M2", "url": "https://omabrowser.org/oma/group/E1C6M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IJ28-1", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "gene_name": "Foxred2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGPLGLLLALAMHLAVCTRPHRDYCVLGAGPAGLQMAALLQRAGRDYEVFERESAPGSFFTRYPRHRKLISINKRHTGKANAEFNLRHDWNSLLSDDPRLLFRHYSKAYFPDASDMVHYLGDFAKCLGLRVLYNTNITHVTLDKDPQAWNGHYFILTDQNGQAYQCSVLLVATGLSVPKLVDFPGSEHVEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSLDGLLESDLEYLALVKDSKGKLHITLKFLLEENNSSQSADSIPLPQDENDNFAMRVAYDRVIRCLGWKFDFSIFNQSLRLSSGTEFSKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHGIAWPSTEHPITQLTSSIIRRVNEASGLYQMFSVLADIILLKENATAFEYLEEFPMQMLAQLETLTGRTARHGLFVINMEYGKNFSGPEKDVFYYDRSVAHIEDAWRSNFLHPVIYFYRHLPTEQDMRFRPAQWPLPRPVAVHHIVEDFLTDWTAPVGHILPLRRFLENCLDTDLRSFYAESCFLFTLTRQRLPPFCQQGYLKMQGVSSTKSLRQHGVESRLLQDYTTMEDSNLWLGDQPSAPGPLTQSLDSNKEEL", "length": 666 }, "evidence": [ { "id": "E1C6M2", "url": "https://omabrowser.org/oma/group/E1C6M2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3USW5-1", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "gene_name": "Foxred2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPSGLLVALALHLAVCSRPHRDYCVLGAGPAGLQMAAFLHRAGRDYEVFERESAPGSFFTRYPRHRKLISINKRHTGKANAEFNLRHDWNSLLSDDPHLLFRHYSQAYFPDASDMVRYLGDFARRLGLHVLYNTNITHVTLDKDPQAWNGHYFILTDQKGQVYQCSVLLVATGLAVPKLVDFPGSEYVEGYESVSVDPEDFVGQNVLILGHGNSAFETAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSLDGLLESDLEYLALVKDSKGKFHVTLKFLLENNSSQSADSIPLPEDDNDNFAMRVAYDRVIRCLGWTFDFSIFDQSLRLSSGTEFSKKYPLIKASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHGIPWPSTEYPITQLTSSIIRRVNEASGLYQMFSVLADIILLKENATAFEYLEEFPMQMLAQLEMLTGRTARHGLFVINMEYGKNFSGPEKDVFYYDRSVAHIEDAWMSNFLHPVIYYYRHLPTEQDMRFRPAQWPLPRPTAIHHIVEDFLTDWTAPVGHILPLRRFLENCLDTDLRSFYAESCFLFTLTRQRLPPFCQQGYLRMQGLSSTKSLWQHGVESRLLQDYTAMENSNRWLGDHSTAPEPLTQSLDSNKEEL", "length": 665 }, "evidence": [ { "id": "E1C6M2", "url": "https://omabrowser.org/oma/group/E1C6M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWF2-1", "protein_name": "FAD-dependent oxidoreductase domain-containing protein 2", "gene_name": "FOXRED2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLSAAAPLWGPPGLLLAIALHPALSVPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYFPDARDMVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYFILTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSLDGLLESDLTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAFGKKYPLIRASYESKGSRGLFILGTASHSVDYRKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGVLADVILLKENSTAFEYLEEFPIQMLAQLETLTGRKAKHGLFVINMEYGRNFSGPDKDVFFDDRSVGHTEDAWQSNFLHPVIYYYRYLPTEQEVRFRPAHWPLPRPTAIHHIVEDFLTDWTAPIGHILPLRRFLENCLDTDLRSFYAESCFLFALTRQKLPPFCQQGYLRMQGLVSTESLWQHRVESRLLRDYAPTGRRLEDSSQQLGDQEPLGSPLAPGPLAQSVDSNKEEL", "length": 684 }, "evidence": [ { "id": "E1C6M2", "url": "https://omabrowser.org/oma/group/E1C6M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "E1C6M2", "url": "https://www.uniprot.org/uniprotkb/E1C6M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C6M2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 680, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C6M2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C6M2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 496, "end_pos": 498 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NCA3-1", "uniprot_ac": "F1NCA3", "uniprot_id": "F1NCA3_CHICK", "mass": { "chemical_mass": 30706.0, "monoisotopic_mass": 30706.0 }, "refseq": { "ac": "XP_416293", "name": "GTP-binding protein Rhes", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416293" }, "gene_names": [ { "name": "RASD2", "type": "recommended", "evidence": [ { "id": "F1NCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ] }, { "name": "RASD2", "type": "synonym", "evidence": [ { "id": "XP_416293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416293" } ] } ], "protein_names": [ { "name": "GTP-binding protein Rhes", "type": "synonym", "evidence": [ { "id": "XP_416293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416293" } ] }, { "name": "RASD family member 2", "type": "synonym", "evidence": [ { "id": "F1NCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCA3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_416293.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416293" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RASD2", "url": "https://www.uniprot.org/uniprotkb/F1NCA3", "locus": { "chromosome": "1", "start_pos": 52076946, "end_pos": 52085341, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010015117", "url": "https://www.ensembl.org/id/ENSGALG00010015117" } ] } } ], "crossref": [ { "id": "F1NCA3", "url": "https://alphafold.ebi.ac.uk/entry/F1NCA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012542", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012542", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418057", "url": "https://www.ncbi.nlm.nih.gov/gene/418057", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418057", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418057", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLKNRTK", "url": "https://omabrowser.org/oma/group/CLKNRTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXW3", "url": "https://www.orthodb.org/?gene=A0A8V0YXW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NCA3", "url": "https://www.orthodb.org/?gene=F1NCA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46149:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46149:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YXW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NCA3-1", "url": "https://www.uniprot.org/uniprotkb/F1NCA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMKTMSSGNCTLNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKESADLPMVICGNKNDHSEIYRKVRSDEGENLVSSDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISIQYGDTFQQKSFRMRRVKDMDAYGMISPFARRPSVNSDLKYIKSKVLREGQSREREKCTIQ", "length": 266, "header": "tr|F1NCA3-1|F1NCA3_CHICK Isoform 1 of RASD family member 2 OS=Gallus gallus OX=9031 GN=RASD2 PE=3 SV=2 CANONICAL=F1NCA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXW3-1", "url": "https://www.uniprot.org/uniprotkb/F1NCA3/entry#A0A8V0YXW3-1", "sequence": { "sequence": "MLFDQLMVHAMMKTMSSGNCTLNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKESADLPMVICGNKNDHSEIYRKVRSDEGENLVSSDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISIQYGDTFQQKSFRMRRVKDMDAYGMISPFARRPSVNSDLKYIKSKVLREGQSREREKCTIQ", "length": 276, "header": "tr|A0A8V0YXW3-1|F1NCA3_CHICK Computationally mapped isoform of RASD family member 2 OS=Gallus gallus OX=9031 GN=RASD2 PE=3 SV=1 CANONICAL=F1NCA3-1" }, "locus": { "chromosome": "1", "start_pos": 52081144, "end_pos": 52078687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036403.1", "url": "https://www.ensembl.org/id/ENSGALT00010036403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021178.1", "url": "https://www.ensembl.org/id/ENSGALP00010021178.1" } ] } }, { "isoform_ac": "F1NCA3-1", "url": "https://www.uniprot.org/uniprotkb/F1NCA3/entry#F1NCA3-1", "sequence": { "sequence": "MMKTMSSGNCTLNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKESADLPMVICGNKNDHSEIYRKVRSDEGENLVSSDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISIQYGDTFQQKSFRMRRVKDMDAYGMISPFARRPSVNSDLKYIKSKVLREGQSREREKCTIQ", "length": 266, "header": "tr|F1NCA3-1|F1NCA3_CHICK Isoform 1 of RASD family member 2 OS=Gallus gallus OX=9031 GN=RASD2 PE=3 SV=2 CANONICAL=F1NCA3-1" }, "locus": { "chromosome": "1", "start_pos": 52081041, "end_pos": 52078687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010036406.1", "url": "https://www.ensembl.org/id/ENSGALT00010036406.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010021181.1", "url": "https://www.ensembl.org/id/ENSGALP00010021181.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418057", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418057", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I3L0-1", "protein_name": "GTP-binding protein Rhes", "gene_name": "LOC100766916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEVAELPMVICGNKNDHSELCRQVTAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSMAKLPHEMSPALHHKISVQYGDAFHPRPFCMRRTKVAGAYGMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCSIQ", "length": 266 }, "evidence": [ { "id": "F1NCA3", "url": "https://omabrowser.org/oma/group/F1NCA3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P63032-1", "protein_name": "GTP-binding protein Rhes", "gene_name": "Rasd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMKTLSSGNCTLNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSMAKLPHEMSPALHHKISVQYGDAFHPRPFCMRRTKVAGAYGMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCSIQ", "length": 266 }, "evidence": [ { "id": "F1NCA3", "url": "https://omabrowser.org/oma/group/F1NCA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P63033-1", "protein_name": "GTP-binding protein Rhes", "gene_name": "Rasd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMKTLSSGNCTLNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSMAKLPHEMSPALHHKISVQYGDAFHPRPFCMRRTKVAGAYGMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCSIQ", "length": 266 }, "evidence": [ { "id": "F1NCA3", "url": "https://omabrowser.org/oma/group/F1NCA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96D21-1", "protein_name": "GTP-binding protein Rhes", "gene_name": "RASD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTIQ", "length": 266 }, "evidence": [ { "id": "F1NCA3", "url": "https://omabrowser.org/oma/group/F1NCA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G-protein beta-subunit binding", "id": "GO:0031681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031681", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" }, { "name": "synaptic transmission, dopaminergic", "id": "GO:0001963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001963", "evidence": [ { "database": "UniProtKB", "id": "F1NCA3", "url": "https://www.uniprot.org/uniprotkb/F1NCA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NB17-1", "uniprot_ac": "F1NB17", "uniprot_id": "F1NB17_CHICK", "mass": { "chemical_mass": 39981.0, "monoisotopic_mass": 39981.0 }, "refseq": { "ac": "NP_989859", "name": "endophilin-A3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" }, "gene_names": [ { "name": "SH3GL3", "type": "recommended", "evidence": [ { "id": "F1NB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ] }, { "name": "SH3GL3", "type": "synonym", "evidence": [ { "id": "NP_989859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] }, { "name": "SH3P13", "type": "synonym", "evidence": [ { "id": "NP_989859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] } ], "protein_names": [ { "name": "SH3 domain containing GRB2 like 3, endophilin A3", "type": "synonym", "evidence": [ { "id": "F1NB17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB17/entry#names_and_taxonomy" } ] }, { "name": "SH3 domain-containing GRB2-like protein 3", "type": "synonym", "evidence": [ { "id": "NP_989859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] }, { "name": "SH3-domain GRB2-like 3", "type": "synonym", "evidence": [ { "id": "NP_989859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] }, { "name": "endophilin III", "type": "synonym", "evidence": [ { "id": "NP_989859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] }, { "name": "endophilin-3", "type": "synonym", "evidence": [ { "id": "NP_989859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] }, { "name": "endophilin-A3", "type": "synonym", "evidence": [ { "id": "NP_989859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01000151.1, HAEL01009274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000245.1. On Sep 23, 2021 this sequence version replaced NP_989859.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH3GL3", "url": "https://www.uniprot.org/uniprotkb/F1NB17", "locus": { "chromosome": "10", "start_pos": 11475591, "end_pos": 11431225, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016810", "url": "https://www.ensembl.org/id/ENSGALG00010016810" } ] } } ], "crossref": [ { "id": "F1NB17", "url": "https://alphafold.ebi.ac.uk/entry/F1NB17", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006045", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006045", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07615", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07615", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11803", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11803", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395201", "url": "https://www.ncbi.nlm.nih.gov/gene/395201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395201", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395201", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NFLENDX", "url": "https://omabrowser.org/oma/group/NFLENDX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YY21", "url": "https://www.orthodb.org/?gene=A0A8V0YY21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZJ0", "url": "https://www.orthodb.org/?gene=A0A8V0YZJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4S3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4S8", "url": "https://www.orthodb.org/?gene=A0A8V0Z4S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4T8", "url": "https://www.orthodb.org/?gene=A0A8V0Z4T8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NB17", "url": "https://www.orthodb.org/?gene=F1NB17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14167:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14167:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-182971", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-182971", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807004", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807004", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989859", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YY21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4S3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4T8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NB17-1", "url": "https://www.uniprot.org/uniprotkb/F1NB17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDEEFQEMERKIDVTNKAVAELLSKSTEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMIRYGRELGDDSMFGLALLDAGESMKQMAEVKDSLDINVKQNFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRLGKIPDEEVKQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHKQSTEILEDLQSKLQNRINVASSRPKREFKPKPVITTTLETGDNQQHNGIAYSSSIKSSGSSMHVDQPCCQALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLNGESGFFPINYVEVMVPLPQ", "length": 353, "header": "tr|F1NB17-1|F1NB17_CHICK Isoform 1 of SH3 domain containing GRB2 like 3, endophilin A3 OS=Gallus gallus OX=9031 GN=SH3GL3 PE=3 SV=3 CANONICAL=F1NB17-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YY21-1", "url": "https://www.uniprot.org/uniprotkb/F1NB17/entry#A0A8V0YY21-1", "sequence": { "sequence": "MAYRTRVLSELFSEKISGAEGTKLDEEFQEMERKIDVTNKAVAELLSKSTEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMIRYGRELGDDSMFGLALLDAGESMKQMAEVKDSLDINVKQNFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRLGKIPDEEVKQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHKQSTEILEDLQSKLQNRINVASSRPKREFKPKPVITTTLETGDNQQHNGIAYSSSIKSSGSSMHVDQPCCQALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLNGESGFFPINYVEVMVPLPQ", "length": 348, "header": "tr|A0A8V0YY21-1|F1NB17_CHICK Computationally mapped isoform of SH3 domain containing GRB2 like 3, endophilin A3 OS=Gallus gallus OX=9031 GN=SH3GL3 PE=3 SV=1 CANONICAL=F1NB17-1" }, "locus": { "chromosome": "10", "start_pos": 11474675, "end_pos": 11460012, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040553.1", "url": "https://www.ensembl.org/id/ENSGALT00010040553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023543.1", "url": "https://www.ensembl.org/id/ENSGALP00010023543.1" } ] } }, { "isoform_ac": "A0A8V0YZJ0-1", "url": "https://www.uniprot.org/uniprotkb/F1NB17/entry#A0A8V0YZJ0-1", "sequence": { "sequence": "EFQEMERKIDVTNKAVAELLSKSTEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMIRYGRELGDDSMFGLALLDAGESMKQMAEVKDSLDINVKQNFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRLGKIPDEEVKQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHKQSTEILEDLQSKLQNRINVASSRPKREFKPKPVITTTLETGDNQQHNGIAYSSSIKSSGSSMHVDQPCCQALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLNGESGFFPINYVEVMVPLPQ", "length": 322, "header": "tr|A0A8V0YZJ0-1|F1NB17_CHICK Computationally mapped isoform of SH3 domain containing GRB2 like 3, endophilin A3 OS=Gallus gallus OX=9031 GN=SH3GL3 PE=3 SV=1 CANONICAL=F1NB17-1" }, "locus": { "chromosome": "10", "start_pos": 11474675, "end_pos": 11460434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040566.1", "url": "https://www.ensembl.org/id/ENSGALT00010040566.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023552.1", "url": "https://www.ensembl.org/id/ENSGALP00010023552.1" } ] } }, { "isoform_ac": "A0A8V0Z4S3-1", "url": "https://www.uniprot.org/uniprotkb/F1NB17/entry#A0A8V0Z4S3-1", "sequence": { "sequence": "MARPEGTHASEAIPQGLIHKLFSEKISGAEGTKLDEEFQEMERKIDVTNKAVAELLSKSTEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMIRYGRELGDDSMFGLALLDAGESMKQMAEVKDSLDINVKQNFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRLGKIPDEEVKQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHKQSTEILEDLQSKLQNRINVASSRPKREFKPKPVITTTLETGDNQQHNGIAYSSSIKSSGSSMHVDQPCCQALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLNGESGFFPINYVEVMVPLPQ", "length": 358, "header": "tr|A0A8V0Z4S3-1|A0A8V0Z4S3_CHICK Computationally mapped isoform of SH3 domain containing GRB2 like 3, endophilin A3 OS=Gallus gallus OX=9031 GN=SH3GL3 PE=3 SV=1 CANONICAL=F1NB17-1" }, "locus": { "chromosome": "10", "start_pos": 11474675, "end_pos": 11448624, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040555.1", "url": "https://www.ensembl.org/id/ENSGALT00010040555.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023545.1", "url": "https://www.ensembl.org/id/ENSGALP00010023545.1" } ] } }, { "isoform_ac": "A0A8V0Z4S8-1", "url": "https://www.uniprot.org/uniprotkb/F1NB17/entry#A0A8V0Z4S8-1", "sequence": { "sequence": "MQLFSEKISGAEGTKLDEEFQEMERKIDVTNKAVAELLSKSTEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMIRYGRELGDDSMFGLALLDAGESMKQMAEVKDSLDINVKQNFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRLGKIPDEEVKQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHKQSTEILEDLQSKLQNRINVASSRPKREFKPKPVITTTLETGDNQQHNGIAYSSSIKSSGSSMHVDQPCCQALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLNGESGFFPINYVEVMVPLPQ", "length": 340, "header": "tr|A0A8V0Z4S8-1|A0A8V0Z4S8_CHICK Computationally mapped isoform of SH3 domain containing GRB2 like 3, endophilin A3 OS=Gallus gallus OX=9031 GN=SH3GL3 PE=3 SV=1 CANONICAL=F1NB17-1" }, "locus": { "chromosome": "10", "start_pos": 11474675, "end_pos": 11434499, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040563.1", "url": "https://www.ensembl.org/id/ENSGALT00010040563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023550.1", "url": "https://www.ensembl.org/id/ENSGALP00010023550.1" } ] } }, { "isoform_ac": "A0A8V0Z4T8-1", "url": "https://www.uniprot.org/uniprotkb/F1NB17/entry#A0A8V0Z4T8-1", "sequence": { "sequence": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDEEFQEMERKIDVTNKAVAELLSKSTEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMIRYGRELGDDSMFGLALLDAGESMKQMAEVKDSLDINVKQNFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRLGKIPDEEVKQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHKQSTEILEDLQSKLQNRINVASSRPKREFKPKPVITTTLETGDNQQHNGIAYSSSIKSSGSSMHVDQPCCQALYDFEPENEGELGFKEGDIITLTNQIDENCRRIRVL", "length": 334, "header": "tr|A0A8V0Z4T8-1|A0A8V0Z4T8_CHICK Computationally mapped isoform of SH3 domain containing GRB2 like 3, endophilin A3 OS=Gallus gallus OX=9031 GN=SH3GL3 PE=3 SV=1 CANONICAL=F1NB17-1" }, "locus": { "chromosome": "10", "start_pos": 11475529, "end_pos": 11431372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040579.1", "url": "https://www.ensembl.org/id/ENSGALT00010040579.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023560.1", "url": "https://www.ensembl.org/id/ENSGALP00010023560.1" } ] } }, { "isoform_ac": "F1NB17-1", "url": "https://www.uniprot.org/uniprotkb/F1NB17/entry#F1NB17-1", "sequence": { "sequence": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDEEFQEMERKIDVTNKAVAELLSKSTEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMIRYGRELGDDSMFGLALLDAGESMKQMAEVKDSLDINVKQNFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRLGKIPDEEVKQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHKQSTEILEDLQSKLQNRINVASSRPKREFKPKPVITTTLETGDNQQHNGIAYSSSIKSSGSSMHVDQPCCQALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLNGESGFFPINYVEVMVPLPQ", "length": 353, "header": "tr|F1NB17-1|F1NB17_CHICK Isoform 1 of SH3 domain containing GRB2 like 3, endophilin A3 OS=Gallus gallus OX=9031 GN=SH3GL3 PE=3 SV=3 CANONICAL=F1NB17-1" }, "locus": { "chromosome": "10", "start_pos": 11474675, "end_pos": 11431372, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040572.1", "url": "https://www.ensembl.org/id/ENSGALT00010040572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023556.1", "url": "https://www.ensembl.org/id/ENSGALP00010023556.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395201", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395201", "resource": "KEGG Pathway" }, { "id": "R-GGA-182971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-182971", "resource": "Reactome", "description": "EGFR downregulation" }, { "id": "R-GGA-6807004", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807004", "resource": "Reactome", "description": "Negative regulation of MET activity" }, { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9T4I0-1", "protein_name": "SH3 domain containing GRB2 like 3, endophilin A3", "gene_name": "SH3GL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVAGLKKQFHKASQLFSEKISGVEGTKLDDEFLDMERKIDITNKAVAEILSKATEYLQPNPAYRAKLGMLNTMSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEGSTFGSALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQSKLQMRISAASNVPKREYKPRPIKRSPSELNGVSTASSAKTTGSNVPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGILHGESGFFPINYVEVIVPLPQ", "length": 347 }, "evidence": [ { "id": "F1NB17", "url": "https://omabrowser.org/oma/group/F1NB17/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O35180-1", "protein_name": "Endophilin-A3", "gene_name": "Sh3gl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDEEFLDMEKKIDITSKAVAEILSKATEYLQPNPAYRAKLGMLNTMSKLRGQVKATGYPQTEGLLGDCMLKYGRELGEDSAFGNSLVEVGEALKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKKRVGKIPEEEIRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQNKLELRIALASQVPRRDYMPKPVNTSSTNANGVEPSSSSKLTGTDIPSDQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVEVIVPLPR", "length": 347 }, "evidence": [ { "id": "F1NB17", "url": "https://omabrowser.org/oma/group/F1NB17/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62421-1", "protein_name": "Endophilin-A3", "gene_name": "Sh3gl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDEEFLNMEKKIDITSKAVAEILSKATEYLQPNPAYRAKLGMLNTVSKLRGQVKATGYPQTEGLLGDCMLKYGKELGEDSAFGNSLVDVGEALKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKRRVGKIPEEEIRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQSKLELRISLASKVPKREFMPKPVNMSSTDANGVGPSSSSKTPGTDTPADQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVEVIVPLPP", "length": 347 }, "evidence": [ { "id": "F1NB17", "url": "https://omabrowser.org/oma/group/F1NB17/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99963-1", "protein_name": "Endophilin-A3", "gene_name": "SH3GL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ", "length": 347 }, "evidence": [ { "id": "F1NB17", "url": "https://omabrowser.org/oma/group/F1NB17/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NB17", "url": "https://www.uniprot.org/uniprotkb/F1NB17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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{ "uniprot_canonical_ac": "F1NH19-1", "uniprot_ac": "F1NH19", "uniprot_id": "F1NH19_CHICK", "mass": { "chemical_mass": 26286.0, "monoisotopic_mass": 26286.0 }, "refseq": { "ac": "XP_004947578", "name": "complement C1q subcomponent subunit B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947578" }, "gene_names": [ { "name": "C1QB", "type": "recommended", "evidence": [ { "id": "F1NH19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ] }, { "name": "C1QB", "type": "synonym", "evidence": [ { "id": "XP_004947578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947578" } ] } ], "protein_names": [ { "name": "Complement C1q B chain", "type": "synonym", "evidence": [ { "id": "F1NH19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH19/entry#names_and_taxonomy" } ] }, { "name": "complement C1q subcomponent subunit B", "type": "synonym", "evidence": [ { "id": "XP_004947578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947578" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947578" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1QB", "url": "https://www.uniprot.org/uniprotkb/F1NH19", "locus": { "chromosome": "21", "start_pos": 6055161, "end_pos": 6058716, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016881", "url": "https://www.ensembl.org/id/ENSGALG00010016881" } ] } } ], "crossref": [ { "id": "F1NH19", "url": "https://alphafold.ebi.ac.uk/entry/F1NH19", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004771", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004771", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428197", "url": "https://www.ncbi.nlm.nih.gov/gene/428197", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428197", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428197", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAMLICL", "url": "https://omabrowser.org/oma/group/WAMLICL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YY31", "url": "https://www.orthodb.org/?gene=A0A8V0YY31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZW9", "url": "https://www.orthodb.org/?gene=A0A8V0YZW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZX4", "url": "https://www.orthodb.org/?gene=A0A8V0YZX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NH19", "url": "https://www.orthodb.org/?gene=F1NH19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-173623", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-173623", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2132263", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132263", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2132286", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132286", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-977606", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004947578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YY31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YY31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH19-1", "url": "https://www.uniprot.org/uniprotkb/F1NH19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTVWVVLICLAGGQLASATLCKTYGTIPGIPGSPGQPGTNGRDGKNGPKGEQGPPGLVEHEQDMGEKGDPGEPGYPGKVGPRGLPGSKGLPGPMGPPGPRGDTGDYKVTLKSAFSAARTFSSFPRRDYPIRFDRIITNENRHYENRYGRFTCQVPGVYYFTYHVTSKGSLCLRMKKGRGGSRDEKVVTFCDYVQNSYQVTTGGVVLRLAANESVWLEPTEKNSIMGIEGADSIFSGFLIFPEV", "length": 244, "header": "tr|F1NH19-1|F1NH19_CHICK Isoform 1 of Complement C1q B chain OS=Gallus gallus OX=9031 GN=C1QB PE=1 SV=3 CANONICAL=F1NH19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YY31-1", "url": "https://www.uniprot.org/uniprotkb/F1NH19/entry#A0A8V0YY31-1", "sequence": { "sequence": "MQTVWVVLICLAGGQLASATLCKTYGTIPGIPGSPGQPGTNGRDGKNGPKGEQGPPGLVEHEQDMGEKGDPGEPGYPGKVGPRGLPGSKGLPGPMGPPGPRGDTGDYKVTLKSAFSAARTFSSFPRRDYPIRFDRIITNENRHYENRYGRFTCQVPGVYYFTYHVTSKGSLCLRMKKGRGGSRDEKLKLVKQHLLVAKPELTPRSCTRWCCGPHLWSQTSTEIQHVPMQSPGAQKISPKS", "length": 240, "header": "tr|A0A8V0YY31-1|F1NH19_CHICK Computationally mapped isoform of Complement C1q B chain OS=Gallus gallus OX=9031 GN=C1QB PE=1 SV=1 CANONICAL=F1NH19-1" }, "locus": { "chromosome": "21", "start_pos": 6057867, "end_pos": 6055169, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040733.1", "url": "https://www.ensembl.org/id/ENSGALT00010040733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023698.1", "url": "https://www.ensembl.org/id/ENSGALP00010023698.1" } ] } }, { "isoform_ac": "A0A8V0YZW9-1", "url": "https://www.uniprot.org/uniprotkb/F1NH19/entry#A0A8V0YZW9-1", "sequence": { "sequence": "MRSQRVWSLQDHKKSGLGPATKYFPSFMEDKMQTVWVVLICLAGGQLASATLCKTYGTIPGIPGSPGQPGTNGRDGKNGPKGEQGPPGLVEHEQDMGEKGDPGEPGYPGKVGPRGLPGSKGLPGPMGPPGPRGDTGDYKVTLKSAFSAARTFSSFPRRDYPIRFDRIITNENRHYENRYGRFTCQVPGVYYFTYHVTSKGSLCLRMKKGRGGSRDEKVVTFCDYVQNSYQVTTGGVVLRLAANESVWLEPTEKNSIMGIEGADSIFSGFLIFPEV", "length": 275, "header": "tr|A0A8V0YZW9-1|F1NH19_CHICK Computationally mapped isoform of Complement C1q B chain OS=Gallus gallus OX=9031 GN=C1QB PE=1 SV=1 CANONICAL=F1NH19-1" }, "locus": { "chromosome": "21", "start_pos": 6058068, "end_pos": 6056649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040724.1", "url": "https://www.ensembl.org/id/ENSGALT00010040724.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023689.1", "url": "https://www.ensembl.org/id/ENSGALP00010023689.1" } ] } }, { "isoform_ac": "A0A8V0YZX4-1", "url": "https://www.uniprot.org/uniprotkb/F1NH19/entry#A0A8V0YZX4-1", "sequence": { "sequence": "MPAGWGALLSHISAQISVVYFPVPLCRPAGLSCGHNPSSSCFLGPPGLVEHEQDMGEKGDPGEPGYPGKVGPRGLPGSKGLPGPMGPPGPRGDTGDYKVTLKSAFSAARTFSSFPRRDYPIRFDRIITNENRHYENRYGRFTCQVPGVYYFTYHVTSKGSLCLRMKKGRGGSRDEKVVTFCDYVQNSYQVTTGGVVLRLAANESVWLEPTEKNSIMGIEGADSIFSGFLIFPEV", "length": 234, "header": "tr|A0A8V0YZX4-1|F1NH19_CHICK Computationally mapped isoform of Complement C1q B chain OS=Gallus gallus OX=9031 GN=C1QB PE=1 SV=1 CANONICAL=F1NH19-1" }, "locus": { "chromosome": "21", "start_pos": 6057350, "end_pos": 6056649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040729.1", "url": "https://www.ensembl.org/id/ENSGALT00010040729.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023694.1", "url": "https://www.ensembl.org/id/ENSGALP00010023694.1" } ] } }, { "isoform_ac": "F1NH19-1", "url": "https://www.uniprot.org/uniprotkb/F1NH19/entry#F1NH19-1", "sequence": { "sequence": "MQTVWVVLICLAGGQLASATLCKTYGTIPGIPGSPGQPGTNGRDGKNGPKGEQGPPGLVEHEQDMGEKGDPGEPGYPGKVGPRGLPGSKGLPGPMGPPGPRGDTGDYKVTLKSAFSAARTFSSFPRRDYPIRFDRIITNENRHYENRYGRFTCQVPGVYYFTYHVTSKGSLCLRMKKGRGGSRDEKVVTFCDYVQNSYQVTTGGVVLRLAANESVWLEPTEKNSIMGIEGADSIFSGFLIFPEV", "length": 244, "header": "tr|F1NH19-1|F1NH19_CHICK Isoform 1 of Complement C1q B chain OS=Gallus gallus OX=9031 GN=C1QB PE=1 SV=3 CANONICAL=F1NH19-1" }, "locus": { "chromosome": "21", "start_pos": 6057867, "end_pos": 6056649, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040725.1", "url": "https://www.ensembl.org/id/ENSGALT00010040725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023690.1", "url": "https://www.ensembl.org/id/ENSGALP00010023690.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Activation of C1r by proteolytic cleavage.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1976", "authors": "Ziccardi RJ, Cooper NR", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132286", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132286" } ], "reference": [ { "type": "PubMed", "id": "1249422", "url": "https://glygen.org/publication/PubMed/1249422" } ] }, { "title": "Physicochemical and functional characterization of the C1r subunit of the first complement component.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1976", "authors": "Ziccardi RJ, Cooper NR", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132286", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132286" } ], "reference": [ { "type": "PubMed", "id": "814163", "url": "https://glygen.org/publication/PubMed/814163" } ] }, { "title": "Structural analysis of chicken factor B-like protease and comparison with mammalian complement proteins factor B and C2.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1993-10-15", "authors": "Kjalke M, Welinder K G, Koch C", "evidence": [ { "database": "Reactome", "id": "R-GGA-2132263", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132263" } ], "reference": [ { "type": "PubMed", "id": "8409391", "url": "https://glygen.org/publication/PubMed/8409391" } ] } ], "pathway": [ { "id": "gga:428197", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428197", "resource": "KEGG Pathway" }, { "id": "R-GGA-173623", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-173623", "resource": "Reactome", "description": "Classical antibody-mediated complement activation" }, { "id": "R-GGA-2132263", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132263", "resource": "Reactome", "description": "Creation of classical C3 convertase" }, { "id": "R-GGA-2132286", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2132286", "resource": "Reactome", "description": "Classical antibody-mediated complement activation" }, { "id": "R-GGA-977606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977606", "resource": "Reactome", "description": "Regulation of Complement cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W0H9-1", "protein_name": "Complement C1q B chain", "gene_name": "C1QB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKTLRGSVPALLPLLLLNLLHVSQAQVFCMPGIPGIPGIPGPDGIPGTPGIKGEKGLPGQVRDHNEVGEKGDPGIPGIPGKVGPKGPIGPKGTPGPPGARGPKGESGDYKATQKIAFSAKRTINTHLRPDQAIRFDQVITNANENYESRSGKFTCKVPGLYYFTYHASSRGNLCVNLMRGREQVRKVVTFCDQVQNTFQVTTGSIVLKLEVEETVFLQATEKSSLLGIDGANTIFSGFLLFPDAEA", "length": 246 }, "evidence": [ { "id": "F1NH19", "url": "https://omabrowser.org/oma/group/F1NH19/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HIN3-1", "protein_name": "Complement C1q subcomponent subunit B", "gene_name": "C1qb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKTWGYMVSTPLLLLFLGLLHVSWAQSSCTGPPRIPGIPGIPGVPGSDGQPGTPGIKGEKGLPGLAGDHGEFGEKGDPGTPGIPGKVGPKGPVGPKGAPGPPGARGPKGDSGDYKATQKVAFSALRTINSPLRRDQAIRFEKAIINMNENYEPRSGKFTCKVPGLYYFTYHASSRGNLCMNLVRGRDRERMQKVLTFCDYAQNTFQVTTGGVVLKLEQDEVVHLQATDKNSLLGLEGANSIFTGFLLFPDMDA", "length": 253 }, "evidence": [ { "id": "F1NH19", "url": "https://omabrowser.org/oma/group/F1NH19/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P02746-1", "protein_name": "Complement C1q subcomponent subunit B", "gene_name": "C1QB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMMKIPWGSIPVLMLLLLLGLIDISQAQLSCTGPPAIPGIPGIPGTPGPDGQPGTPGIKGEKGLPGLAGDHGEFGEKGDPGIPGNPGKVGPKGPMGPKGGPGAPGAPGPKGESGDYKATQKIAFSATRTINVPLRRDQTIRFDHVITNMNNNYEPRSGKFTCKVPGLYYFTYHASSRGNLCVNLMRGRERAQKVVTFCDYAYNTFQVTTGGMVLKLEQGENVFLQATDKNSLLGMEGANSIFSGFLLFPDMEA", "length": 253 }, "evidence": [ { "id": "F1NH19", "url": "https://omabrowser.org/oma/group/F1NH19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P14106-1", "protein_name": "Complement C1q subcomponent subunit B", "gene_name": "C1qb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTQWGEVWTHLLLLLLGFLHVSWAQSSCTGPPGIPGIPGVPGVPGSDGQPGTPGIKGEKGLPGLAGDLGEFGEKGDPGIPGTPGKVGPKGPVGPKGTPGPSGPRGPKGDSGDYGATQKVAFSALRTINSPLRPNQVIRFEKVITNANENYEPRNGKFTCKVPGLYYFTYHASSRGNLCVNLVRGRDRDSMQKVVTFCDYAQNTFQVTTGGVVLKLEQEEVVHLQATDKNSLLGIEGANSIFTGFLLFPDMDA", "length": 253 }, "evidence": [ { "id": "F1NH19", "url": "https://omabrowser.org/oma/group/F1NH19/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P31721-1", "protein_name": "Complement C1q subcomponent subunit B", "gene_name": "C1qb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTQWSEILTPLLLLLLGLLHVSWAQSSCTGSPGIPGVPGIPGVPGSDGKPGTPGIKGEKGLPGLAGDHGELGEKGDAGIPGIPGKVGPKGPVGPKGAPGPPGPRGPKGGSGDYKATQKVAFSALRTVNSALRPNQAIRFEKVITNVNDNYEPRSGKFTCKVPGLYYFTYHASSRGNLCVNIVRGRDRDRMQKVLTFCDYAQNTFQVTTGGVVLKLEQEEVVHLQATDKNSLLGVEGANSIFTGFLLFPDMDV", "length": 253 }, "evidence": [ { "id": "F1NH19", "url": "https://omabrowser.org/oma/group/F1NH19/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KIV9-1", "protein_name": "Complement C1q subcomponent subunit B", "gene_name": "C1QB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKTPRGSVLVLLLLNLLRVSWAQSNCIRPSIPGIPGIPGKPGSDGKPGTPGTKGEKGLPGLVSHLNENGEKGDPGFPGMPGKVGPKGPIGPKGVPGPPGVRGPKGESGDYKATQKIAFSASRTINHHQRQGQPIRFDHVITNANENYQARSSKFTCKVPGLYFFTYHASSRGQLCVDLMRGRAEPQKVVTFCDYVQNTFQVTTGSIVLKLEKDETVFLQATEKNALVGIEGANSIFSGFMLFPDTEA", "length": 247 }, "evidence": [ { "id": "F1NH19", "url": "https://omabrowser.org/oma/group/F1NH19/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ], "pmid": "" }, { "name": "extrinsic component of presynaptic membrane", "id": "GO:0098888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098888", "evidence": [ { "database": "UniProtKB", "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ], "pmid": "" }, { "name": "extrinsic component of postsynaptic membrane", "id": "GO:0098890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098890", "evidence": [ { "database": "UniProtKB", "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synapse pruning", "id": "GO:0098883", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098883", "evidence": [ { "database": "UniProtKB", "id": "F1NH19", "url": "https://www.uniprot.org/uniprotkb/F1NH19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1C8Y8-1", "uniprot_ac": "E1C8Y8", "uniprot_id": "E1C8Y8_CHICK", "mass": { "chemical_mass": 51123.0, "monoisotopic_mass": 51123.0 }, "refseq": { "ac": "XP_015152486", "name": "ERBB receptor feedback inhibitor 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152486" }, "gene_names": [ { "name": "ERRFI1", "type": "recommended", "evidence": [ { "id": "E1C8Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ] }, { "name": "ERRFI1", "type": "synonym", "evidence": [ { "id": "XP_015152486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152486" } ] } ], "protein_names": [ { "name": "ERBB receptor feedback inhibitor 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015152486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152486" } ] }, { "name": "ERBB receptor feedback inhibitor 1", "type": "synonym", "evidence": [ { "id": "E1C8Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152486" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERRFI1", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8", "locus": { "chromosome": "21", "start_pos": 267197, "end_pos": 239011, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018719", "url": "https://www.ensembl.org/id/ENSGALG00010018719" } ] } } ], "crossref": [ { "id": "E1C8Y8", "url": "https://alphafold.ebi.ac.uk/entry/E1C8Y8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000535", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000535", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419364", "url": "https://www.ncbi.nlm.nih.gov/gene/419364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419364", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419364", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YERHKHS", "url": "https://omabrowser.org/oma/group/YERHKHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1C1", "url": "https://www.orthodb.org/?gene=A0A8V0Z1C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z777", "url": "https://www.orthodb.org/?gene=A0A8V0Z777", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C8Y8", "url": "https://www.orthodb.org/?gene=E1C8Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14254:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14254:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z777", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z777", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z777-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z777-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8Y8-1", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTAGVAAQEMRVPLKTGFLHASQGMGGLKTCWGTHSGFENTFFNVDPIAVAYNLNPSAEQRLPSIGHSSNCVSTNDHSFAESCLQVPSQKSSPAPVSPRNEQPISRYEDQLIPGFSKLSLTAGCVSEETPPHMPIKNGPIQFLSASSNDRSSRPLPPLPVPEDITPDEVDREVEFLTSSDTDFLLEDYGLPPFKSSGSSRRSFRGCGQINYAYFDAPTGPKTEDANPTQSINGCISSIYPPPQQLHRRLRRSHSGPAGSLNKPVVRLSGHLNRSSPNSDEDKPEIPPRVPIPPRALKPDYRRWSAEVASSAYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSNKALQRQNSEGSSNRVPCILPIIENGKKASSTHYYLLPERPPYLDKYEKFFREAEETSSNTEVQSWSGDCMATSVPARLDSKPRMDIAGHLKRKHLSYVVSP", "length": 465, "header": "tr|E1C8Y8-1|E1C8Y8_CHICK Isoform 1 of ERBB receptor feedback inhibitor 1 OS=Gallus gallus OX=9031 GN=ERRFI1 PE=4 SV=5 CANONICAL=E1C8Y8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1C1-1", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8/entry#A0A8V0Z1C1-1", "sequence": { "sequence": "MITGGNANCKKPVSSWEFLELGDITTEQYTMSTAGVAAQEMRVPLKTGFLHASQGMGGLKTCWGTHSGFENTFFNVDPIAVAYNLNPSAEQRLPSIGHSSNCVSTNDHSFAESCLQVPSQKSSPAPVSPRNEQPISRYEDQLIPGFSKLSLTAGCVSEETPPHMPIKNGPIQFLSASSNDRSSRPLPPLPVPEDITPDEVDREVEFLTSSDTDFLLEDYGLPPFKSSGSSRRSFRGCGQINYAYFDAPTGPKTEDANPTQSINGCISSIYPPPQQLHRRLRRSHSGPAGSLNKPVVRLSGHLNRSSPNSDEDKPEIPPRVPIPPRALKPDYRRWSAEVASSAYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSNKALQRQNSEGSSNRVPCILPIIENGKKASSTHYYLLPERPPYLDKYEKFFREAEETSSNTEVQSWSGDCMATSVPARLDSKPRMDIAGHLKRKHLSYVVSP", "length": 495, "header": "tr|A0A8V0Z1C1-1|E1C8Y8_CHICK Computationally mapped isoform of ERBB receptor feedback inhibitor 1 OS=Gallus gallus OX=9031 GN=ERRFI1 PE=4 SV=1 CANONICAL=E1C8Y8-1" }, "locus": { "chromosome": "21", "start_pos": 246001, "end_pos": 243014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045240.1", "url": "https://www.ensembl.org/id/ENSGALT00010045240.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027008.1", "url": "https://www.ensembl.org/id/ENSGALP00010027008.1" } ] } }, { "isoform_ac": "A0A8V0Z777-1", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8/entry#A0A8V0Z777-1", "sequence": { "sequence": "MYHNWNANCKKPVSSWEFLELGDITTEQYTMSTAGVAAQEMRVPLKTGFLHASQGMGGLKTCWGTHSGFENTFFNVDPIAVAYNLNPSAEQRLPSIGHSSNCVSTNDHSFAESCLQVPSQKSSPAPVSPRNEQPISRYEDQLIPGFSKLSLTAGCVSEETPPHMPIKNGPIQFLSASSNDRSSRPLPPLPVPEDITPDEVDREVEFLTSSDTDFLLEDYGLPPFKSSGSSRRSFRGCGQINYAYFDAPTGPKTEDANPTQSINGCISSIYPPPQQLHRRLRRSHSGPAGSLNKPVVRLSGHLNRSSPNSDEDKPEIPPRVPIPPRALKPDYRRWSAEVASSAYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSNKALQRQNSEGSSNRVPCILPIIENGKKASSTHYYLLPERPPYLDKYEKFFREAEETSSNTEVQSWSGDCMATSVPARLDSKPRMDIAGHLKRKHLSYVVSP", "length": 495, "header": "tr|A0A8V0Z777-1|A0A8V0Z777_CHICK Computationally mapped isoform of ERBB receptor feedback inhibitor 1 OS=Gallus gallus OX=9031 GN=ERRFI1 PE=4 SV=1 CANONICAL=E1C8Y8-1" }, "locus": { "chromosome": "21", "start_pos": 246001, "end_pos": 243336, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045243.1", "url": "https://www.ensembl.org/id/ENSGALT00010045243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027010.1", "url": "https://www.ensembl.org/id/ENSGALP00010027010.1" } ] } }, { "isoform_ac": "E1C8Y8-1", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8/entry#E1C8Y8-1", "sequence": { "sequence": "MSTAGVAAQEMRVPLKTGFLHASQGMGGLKTCWGTHSGFENTFFNVDPIAVAYNLNPSAEQRLPSIGHSSNCVSTNDHSFAESCLQVPSQKSSPAPVSPRNEQPISRYEDQLIPGFSKLSLTAGCVSEETPPHMPIKNGPIQFLSASSNDRSSRPLPPLPVPEDITPDEVDREVEFLTSSDTDFLLEDYGLPPFKSSGSSRRSFRGCGQINYAYFDAPTGPKTEDANPTQSINGCISSIYPPPQQLHRRLRRSHSGPAGSLNKPVVRLSGHLNRSSPNSDEDKPEIPPRVPIPPRALKPDYRRWSAEVASSAYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSNKALQRQNSEGSSNRVPCILPIIENGKKASSTHYYLLPERPPYLDKYEKFFREAEETSSNTEVQSWSGDCMATSVPARLDSKPRMDIAGHLKRKHLSYVVSP", "length": 465, "header": "tr|E1C8Y8-1|E1C8Y8_CHICK Isoform 1 of ERBB receptor feedback inhibitor 1 OS=Gallus gallus OX=9031 GN=ERRFI1 PE=4 SV=5 CANONICAL=E1C8Y8-1" }, "locus": { "chromosome": "21", "start_pos": 246001, "end_pos": 243932, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045235.1", "url": "https://www.ensembl.org/id/ENSGALT00010045235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027005.1", "url": "https://www.ensembl.org/id/ENSGALP00010027005.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419364", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419364", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3IEU1-1", "protein_name": "ERBB receptor feedback inhibitor 1", "gene_name": "Errfi1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSTAGVSAQDIRVPLKTAFLHNGQALGTMKTCWGSRSEFENNFINIDPITMAYSLNSPTQEHLTTLGCASRSAPVSGHFFAEYGRSPKSSLPPLIIPPSDSSGHREEDQVVCGFKKLSVNGICTSTPPLTPIKNCPSPFPCAAVCDRGSRPLPPLPISEDLSLDEADCEVEFLTSSDTDFLLEDCAPSDFKYDVPGRRSFRGCGQINYAYFDTPTVSVADLSCTSDQNRAVPDPNPPPPQSHRRLRRSHSGPAGSFNKPAIRISSYTHRASPSSDEDKPEVPPRVPIPPRPAKPDYRRWSAEVTSNTYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSSKALQRQSSEGSASKVPCILPIIENGKKVSSTHYYLLPERPPYLDKYEKYFREAEEANPSTQIQPLPAACGVTSATEKLASRMKMDAGGHIKRKHLSYVVSP", "length": 460 }, "evidence": [ { "id": "E1C8Y8", "url": "https://omabrowser.org/oma/group/E1C8Y8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P05432-1", "protein_name": "ERBB receptor feedback inhibitor 1", "gene_name": "Errfi1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTAGVAAQDIRVPLKTGFLHNGQALGNMKTCWGSRNEFEKNFLNIDPITMAYNLNSPAPEHLTTLGCASPSAPGSGHFFAERGPSPKSSLPPLVIPPSESSGQREEDQVLCGFKKLSVNGVCASTPPLTPIQSCSSPFPCAAPCDRSSRPLPPLPISEDPSLDEADCEVEFLTSADTDFLLEDCVPSDFKYDVPGRRSFRGCGQINYAYFDSPTVSVADLSCASDQNRVVPDPNPPPPQSHRRLRRSHSGPAGSFNKPAIRISSCTHRASPSSDEDKPEIPPRVPIPPRPAKPDYRRWSAEVTSNTYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSSKALQRQSSEGSAKAPCILPIIENGKKVSSTHYYLLPERPPYLDKYEKYFREAEEANPSTQIQPLPAACGMVSATDKLASRMKMDVGGHGKRKHLSYVVSP", "length": 459 }, "evidence": [ { "id": "E1C8Y8", "url": "https://omabrowser.org/oma/group/E1C8Y8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99JZ7-1", "protein_name": "ERBB receptor feedback inhibitor 1", "gene_name": "Errfi1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTAGVAAQDIRVPLKTGFLHNGQALGNMKSCWGSHSEFENNFLNIDPITMAYNLNSPAQEHLTTVGCAARSAPGSGHFFAECGPSPRSSLPPLVISPSESSGQREEDQVMCGFKKLSVNGVCTSTPPLTPIKSCPSPFPCAALCDRGSRPLPPLPISEDLCVDEADSEVELLTTSSDTDLLLEDSAPSDFKYDAPGRRSFRGCGQINYAYFDSPTVSVADLSCASDQNRVVPDPNPPPPQSHRRLRRSHSGPAGSFNKPAIRISSCTHRASPSSDEDKPEVPPRVPIPPRPAKPDYRRWSAEVTSNTYSDEDRPPKVPPREPLSRSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSSKALQRQSSEGSANKVPCILPIIENGKKVSSTHYYLLPERPPYLDKYEKYFKEAEETNPSTQIQPLPAACGMASATEKLASRMKIDMGSHGKRKHLSYVVSP", "length": 461 }, "evidence": [ { "id": "E1C8Y8", "url": "https://omabrowser.org/oma/group/E1C8Y8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJM3-1", "protein_name": "ERBB receptor feedback inhibitor 1", "gene_name": "ERRFI1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSIAGVAAQEIRVPLKTGFLHNGRAMGNMRKTYWSSRSEFKNNFLNIDPITMAYSLNSSAQERLIPLGHASKSAPMNGHCFAENGPSQKSSLPPLLIPPSENLGPHEEDQVVCGFKKLTVNGVCASTPPLTPIKNSPSLFPCAPLCERGSRPLPPLPISEALSLDDTDCEVEFLTSSDTDFLLEDSTLSDFKYDVPGRRSFRGCGQINYAYFDTPAVSAADLSYVSDQNGGVPDPNPPPPQTHRRLRRSHSGPAGSFNKPAIRISNCCIHRASPNSDEDKPEVPPRVPIPPRPVKPDYRRWSAEVTSSTYSDEDRPPKVPPREPLSPSNSRTPSPKSLPSYLNGVMPPTQSFAPDPKYVSSKALQRQNSEGSASKVPCILPIIENGKKVSSTHYYLLPERPPYLDKYEKFFREAEETNGGAQIQPLPADCGISSATEKPDSKTKMDLGGHVKRKHLSYVVSP", "length": 462 }, "evidence": [ { "id": "E1C8Y8", "url": "https://omabrowser.org/oma/group/E1C8Y8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "regulation of keratinocyte differentiation", "id": "GO:0045616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045616", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "skin morphogenesis", "id": "GO:0043589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043589", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "lung vasculature development", "id": "GO:0060426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060426", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" }, { "name": "lung epithelium development", "id": "GO:0060428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060428", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E1C8Y8", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C8Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8Y8" }, { "id": "PF09027", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09027" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cdc42 binding", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 64, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 273, "end_pos": 275 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NH66-1", "uniprot_ac": "F1NH66", "uniprot_id": "F1NH66_CHICK", "mass": { "chemical_mass": 109356.0, "monoisotopic_mass": 109356.0 }, "refseq": { "ac": "XP_001233827", "name": "echinoderm microtubule-associated protein-like 4 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233827" }, "gene_names": [ { "name": "EML4", "type": "recommended", "evidence": [ { "id": "F1NH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ] }, { "name": "EML4", "type": "synonym", "evidence": [ { "id": "XP_001233827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233827" } ] } ], "protein_names": [ { "name": "EMAP like 4", "type": "synonym", "evidence": [ { "id": "F1NH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#names_and_taxonomy" } ] }, { "name": "echinoderm microtubule-associated protein-like 4 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_001233827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233827" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_001233827.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233827" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EML4", "url": "https://www.uniprot.org/uniprotkb/F1NH66", "locus": { "chromosome": "3", "start_pos": 23427603, "end_pos": 23273075, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018756", "url": "https://www.ensembl.org/id/ENSGALG00010018756" } ] } } ], "crossref": [ { "id": "F1NH66", "url": "https://alphafold.ebi.ac.uk/entry/F1NH66", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009915", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009915", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21950", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21950", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771345", "url": "https://www.ncbi.nlm.nih.gov/gene/771345", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771345", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771345", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5NU87", "url": "https://www.orthodb.org/?gene=A0A1D5NU87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1F7", "url": "https://www.orthodb.org/?gene=A0A8V0Z1F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1H0", "url": "https://www.orthodb.org/?gene=A0A8V0Z1H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7Y3", "url": "https://www.orthodb.org/?gene=A0A8V0Z7Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8V9", "url": "https://www.orthodb.org/?gene=A0A8V0Z8V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZET1", "url": "https://www.orthodb.org/?gene=A0A8V0ZET1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NH66", "url": "https://www.orthodb.org/?gene=F1NH66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03451", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03451", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NU87", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NU87-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1F7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1H0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8V9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZET1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZET1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZET1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NH66-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGFAGSLDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSGTEKKKEKSPGQKEKKEESHSNDQSPQTQASPSPQPPSQTLQTHRQTPESKSSAPTKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 988, "header": "tr|F1NH66-1|F1NH66_CHICK Isoform 1 of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=2 CANONICAL=F1NH66-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NU87-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#A0A1D5NU87-1", "sequence": { "sequence": "MDSLLNHYDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSGTEKKKEKSPGQKEKKEESHSNDQSPQTQASPSPQPPSQTLQTHRQTPESKSSAPTKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 988, "header": "tr|A0A1D5NU87-1|A0A1D5NU87_CHICK Computationally mapped isoform of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=1 CANONICAL=F1NH66-1" }, "locus": { "chromosome": "3", "start_pos": 23425242, "end_pos": 23310588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045325.1", "url": "https://www.ensembl.org/id/ENSGALT00010045325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027057.1", "url": "https://www.ensembl.org/id/ENSGALP00010027057.1" } ] } }, { "isoform_ac": "A0A8V0Z1F7-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#A0A8V0Z1F7-1", "sequence": { "sequence": "MEGSLPCLAAGCDPAALESFCADDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSGTEKKKEKSPGQKEKKEESHSNDQSPQTQASPSPQPPSQTLQTHRQTPESKSSAPTKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 1002, "header": "tr|A0A8V0Z1F7-1|F1NH66_CHICK Computationally mapped isoform of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=1 CANONICAL=F1NH66-1" }, "locus": { "chromosome": "3", "start_pos": 23425242, "end_pos": 23337171, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045319.1", "url": "https://www.ensembl.org/id/ENSGALT00010045319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027053.1", "url": "https://www.ensembl.org/id/ENSGALP00010027053.1" } ] } }, { "isoform_ac": "A0A8V0Z1H0-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#A0A8V0Z1H0-1", "sequence": { "sequence": "MDGFAGSLDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSGTEKKKEKSPGQKEKKEESHSNDQSPQTQASPSPQPPSQTLQTHRQTPESKSSAPTKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 977, "header": "tr|A0A8V0Z1H0-1|F1NH66_CHICK Computationally mapped isoform of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=1 CANONICAL=F1NH66-1" }, "locus": { "chromosome": "3", "start_pos": 23425242, "end_pos": 23274356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045344.1", "url": "https://www.ensembl.org/id/ENSGALT00010045344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027068.1", "url": "https://www.ensembl.org/id/ENSGALP00010027068.1" } ] } }, { "isoform_ac": "A0A8V0Z7Y3-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#A0A8V0Z7Y3-1", "sequence": { "sequence": "MSPATRPALHGTRCPISPQRQRAAAALWGSTCPPRCMHERKALAPQQDVATDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSGTEKKKEKSPGQKEKKEESHSNDQSPQTQASPSPQPPSQTLQTHRQTPESKSSAPTKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 1031, "header": "tr|A0A8V0Z7Y3-1|A0A8V0Z7Y3_CHICK Computationally mapped isoform of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=1 CANONICAL=F1NH66-1" }, "locus": { "chromosome": "3", "start_pos": 23425242, "end_pos": 23273283, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045352.1", "url": "https://www.ensembl.org/id/ENSGALT00010045352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027072.1", "url": "https://www.ensembl.org/id/ENSGALP00010027072.1" } ] } }, { "isoform_ac": "A0A8V0Z8V9-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#A0A8V0Z8V9-1", "sequence": { "sequence": "MGRPAAWVGNSASVSERMLLMEGWDMKRCQGDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSGTEKKKEKSPGQKEKKEESHSNDQSPQTQASPSPQPPSQTLQTHRQTPESKSSAPTKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 1011, "header": "tr|A0A8V0Z8V9-1|A0A8V0Z8V9_CHICK Computationally mapped isoform of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=1 CANONICAL=F1NH66-1" }, "locus": { "chromosome": "3", "start_pos": 23425242, "end_pos": 23280414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045329.1", "url": "https://www.ensembl.org/id/ENSGALT00010045329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027061.1", "url": "https://www.ensembl.org/id/ENSGALP00010027061.1" } ] } }, { "isoform_ac": "A0A8V0ZET1-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#A0A8V0ZET1-1", "sequence": { "sequence": "MGRPAAWVGNSASVSERMLLMEGWDMKRCQGDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 953, "header": "tr|A0A8V0ZET1-1|A0A8V0ZET1_CHICK Computationally mapped isoform of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=1 CANONICAL=F1NH66-1" }, "locus": { "chromosome": "3", "start_pos": 23425242, "end_pos": 23280414, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045333.1", "url": "https://www.ensembl.org/id/ENSGALT00010045333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027064.1", "url": "https://www.ensembl.org/id/ENSGALP00010027064.1" } ] } }, { "isoform_ac": "F1NH66-1", "url": "https://www.uniprot.org/uniprotkb/F1NH66/entry#F1NH66-1", "sequence": { "sequence": "MDGFAGSLDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDHVASVRKSAPSKGQPSLREAISMSCITNGSTGSRKTSHISSVSVARKETSLSTAKSGTEKKKEKSPGQKEKKEESHSNDQSPQTQASPSPQPPSQTLQTHRQTPESKSSAPTKSIKRSLTAEKPHSAWESSDDGRNKLLRVASTSKLISKVAKNADKHKDVIISQAKMSTREKNSQEGEYIKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAVHPDKIRIATGQLAGVDKDGRPLQPHVRVWDSVSLVTLQVIGLGTFERGVGCLDFSKADSGTHLCVIDDSNEHMLTVWDWQKKSKVAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLSRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGIILIWSKTTVESTPGKGPKGVYQISRQIKAHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFVLRGTFNDGFLVEVQGHTDELWGLASHPFKDLFLTCAQDRQVCMWNSVDHTLEWTRLLDEPGHCADFHPSGAVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTLLAVGSHDNFIYLYVVTENGRKYSRHGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKVTLPQNDIVVDIGATKVPIPASENAVQSPAPLPQPFNEMNQTDSVTGSSPASLESNLEQSAEASEEQSEQSDGSSLDPAEPGYEEPSNETSEEHSESTVTEEQQENSPES", "length": 988, "header": "tr|F1NH66-1|F1NH66_CHICK Isoform 1 of EMAP like 4 OS=Gallus gallus OX=9031 GN=EML4 PE=1 SV=2 CANONICAL=F1NH66-1" }, "locus": { "chromosome": "3", "start_pos": 23425242, "end_pos": 23274356, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045339.1", "url": "https://www.ensembl.org/id/ENSGALT00010045339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027066.1", "url": "https://www.ensembl.org/id/ENSGALP00010027066.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771345", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771345", "resource": "KEGG Pathway" }, { "id": "R-GGA-9648025", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "resource": "Reactome", "description": "EML4 and NUDC in mitotic spindle formation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "attachment of spindle microtubules to kinetochore", "id": "GO:0008608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008608", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "mitotic metaphase chromosome alignment", "id": "GO:0007080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "F1NH66", "url": "https://www.uniprot.org/uniprotkb/F1NH66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 918, "end_pos": 920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH66" }, { "id": "PF23409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like first beta-propeller", "eco_id": "ECO_0000259", "start_pos": 312, "end_pos": 589, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1NH66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NH66" }, { "id": "PF23414", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like second beta-propeller", "eco_id": "ECO_0000259", "start_pos": 606, "end_pos": 875, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 770, "end_pos": 772 }, { "start_pos": 850, "end_pos": 852 }, { "start_pos": 85, "end_pos": 87 }, { "start_pos": 918, "end_pos": 920 }, { "start_pos": 966, "end_pos": 968 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NG10-1", "uniprot_ac": "F1NG10", "uniprot_id": "F1NG10_CHICK", "mass": { "chemical_mass": 46268.0, "monoisotopic_mass": 46268.0 }, "refseq": { "ac": "NP_001006492", "name": "actin-related protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006492" }, "gene_names": [ { "name": "ACTR10", "type": "recommended", "evidence": [ { "id": "F1NG10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ] }, { "name": "ACTR10", "type": "synonym", "evidence": [ { "id": "NP_001006492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006492" } ] } ], "protein_names": [ { "name": "Actin-related protein 10", "type": "recommended", "evidence": [ { "id": "F1NG10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG10/entry#names_and_taxonomy" } ] }, { "name": "actin-related protein 10 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006492" } ] }, { "name": "actin-related protein 10", "type": "synonym", "evidence": [ { "id": "NP_001006492", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006492" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720851.1, HAEL01000498.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HAEL01000498.1, BX934017.1, AJ720851.1, AJ444760.1 and BU344894.1. On Sep 13, 2021 this sequence version replaced NP_001006492.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006492" } ] }, { "annotation": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2G7#function" }, { "database": "UniProtKB", "id": "ARBA00034687", "url": "https://www.uniprot.org/uniprotkb/ARBA00034687#function" }, { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACTR10", "url": "https://www.uniprot.org/uniprotkb/F1NG10", "locus": { "chromosome": "5", "start_pos": 54883262, "end_pos": 54892264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017435", "url": "https://www.ensembl.org/id/ENSGALG00010017435" } ] } } ], "crossref": [ { "id": "F1NG10", "url": "https://alphafold.ebi.ac.uk/entry/F1NG10", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012041", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012041", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10207", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10207", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423543", "url": "https://www.ncbi.nlm.nih.gov/gene/423543", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423543", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423543", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WERDNDN", "url": "https://omabrowser.org/oma/group/WERDNDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2G7", "url": "https://www.orthodb.org/?gene=A0A8V0Z2G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NG10", "url": "https://www.orthodb.org/?gene=F1NG10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3371497", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811436", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006492", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006492", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NG10-1", "url": "https://www.uniprot.org/uniprotkb/F1NG10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLYEGLGSGGEKTAVVLDLGEAFTKCGFAGETGPRCIIPSEIKKPDVSKPVKVVQYNINTEELYSYLKEFIHMLYFRHLLVNPRDRRVVIIESVLCPSHFRDTLARVLFKHFEVPSVLFAPSHLMSLLTLGINSAMVLDCGYKESLVLPIYEGTPILSCWGSLPLGGKAIHKELEYRLLEQCTVDTGLAKGQSLPSVMGSVPEDVVEDIKVRTCFVSDLQRGLKIQAAKFNIDGSAERPLPPPDVDYPLDGEKILHVVGSIRDSVAEILFEQDNEETSVATLILDSLIQCPIDTRKQLAENLVVMGGTAMLPGFLHRLMAEIRYLVEKPKYKEVLATKTFKVHTPPAKPNYVAWLGGAIFGALQDILGSRSVSREYYSQTGRIPDWCCLSNPPLEMMFDVGKAPPPLMKRAFSTEK", "length": 417, "header": "tr|F1NG10-1|F1NG10_CHICK Isoform 1 of Actin-related protein 10 OS=Gallus gallus OX=9031 GN=ACTR10 PE=1 SV=1 CANONICAL=F1NG10-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2G7-1", "url": "https://www.uniprot.org/uniprotkb/F1NG10/entry#A0A8V0Z2G7-1", "sequence": { "sequence": "MPLYEGLGSGGEKTAVVLDLGEAFTKCGFAGETGPRCIIPSEIKKPDVSKPVKVVQYNINTEELYSYLKEFIHMLYFRHLLVNPRDRRVVIIESVLCPSHFRDTLARVLFKHFEVPSVLFAPSHLMSLLTLGINSAMVLDCGYKESLGNFLICFCWGSLPLGGKAIHKELEYRLLEQCTVDTGLAKGQSLPSVMGSVPEDVVEDIKVRTCFVSDLQRGLKIQAAKFNIDGSAERPLPPPDVDYPLDGEKILHVVGSIRDSVAEILFEQDNEETSVATLILDSLIQCPIDTRKQLAENLVVMGGTAMLPGFLHRLMAEIRYLVEKPKYKEVLATKTFKVHTPPAKPNYVAWLGGAIFGALQDILGSRSVSREYYSQTGRIPDWCCLSNPPLEMMFDVGKAPPPLMKRAFSTEK", "length": 412, "header": "tr|A0A8V0Z2G7-1|F1NG10_CHICK Computationally mapped isoform of Actin-related protein 10 OS=Gallus gallus OX=9031 GN=ACTR10 PE=1 SV=1 CANONICAL=F1NG10-1" }, "locus": { "chromosome": "5", "start_pos": 54892209, "end_pos": 54883741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042090.1", "url": "https://www.ensembl.org/id/ENSGALT00010042090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024645.1", "url": "https://www.ensembl.org/id/ENSGALP00010024645.1" } ] } }, { "isoform_ac": "F1NG10-1", "url": "https://www.uniprot.org/uniprotkb/F1NG10/entry#F1NG10-1", "sequence": { "sequence": "MPLYEGLGSGGEKTAVVLDLGEAFTKCGFAGETGPRCIIPSEIKKPDVSKPVKVVQYNINTEELYSYLKEFIHMLYFRHLLVNPRDRRVVIIESVLCPSHFRDTLARVLFKHFEVPSVLFAPSHLMSLLTLGINSAMVLDCGYKESLVLPIYEGTPILSCWGSLPLGGKAIHKELEYRLLEQCTVDTGLAKGQSLPSVMGSVPEDVVEDIKVRTCFVSDLQRGLKIQAAKFNIDGSAERPLPPPDVDYPLDGEKILHVVGSIRDSVAEILFEQDNEETSVATLILDSLIQCPIDTRKQLAENLVVMGGTAMLPGFLHRLMAEIRYLVEKPKYKEVLATKTFKVHTPPAKPNYVAWLGGAIFGALQDILGSRSVSREYYSQTGRIPDWCCLSNPPLEMMFDVGKAPPPLMKRAFSTEK", "length": 417, "header": "tr|F1NG10-1|F1NG10_CHICK Isoform 1 of Actin-related protein 10 OS=Gallus gallus OX=9031 GN=ACTR10 PE=1 SV=1 CANONICAL=F1NG10-1" }, "locus": { "chromosome": "5", "start_pos": 54892209, "end_pos": 54883741, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042085.1", "url": "https://www.ensembl.org/id/ENSGALT00010042085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024642.1", "url": "https://www.ensembl.org/id/ENSGALP00010024642.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423543", "resource": "KEGG Pathway" }, { "id": "R-GGA-3371497", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3371497", "resource": "Reactome", "description": "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811436", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811436", "resource": "Reactome", "description": "COPI-independent Golgi-to-ER retrograde traffic" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GBD2-1", "protein_name": "Actin-related protein 10", "gene_name": "Actr10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMSKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKGQSLPSVMGSVPESVLEDIKVRTCFVSDLQRGLQIQAAKFNIDGNNERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLLQCPVDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKNFRIHTPPAKANCVAWLGGAVFGALQDILGSRSISKEYYNQTGRTPDWCSLNNPPLEMMFDVGKTQPPLMKRAFSTEK", "length": 417 }, "evidence": [ { "id": "F1NG10", "url": "https://omabrowser.org/oma/group/F1NG10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LHK5-1", "protein_name": "Actin-related protein 10", "gene_name": "ACTR10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSLNNPPLEMVFDVGKSQPPLMKRAFSTEK", "length": 417 }, "evidence": [ { "id": "F1NG10", "url": "https://omabrowser.org/oma/group/F1NG10/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ZBD2-1", "protein_name": "Actin-related protein 10", "gene_name": "ACTR10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIRVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTGAAKEQSLPSVMGSIPEGILEDIKVRTCFVSDLKRGLNIQAAKFNIDGNTERPSPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLAENLVVIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLATKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKDYYNQTGRIPDWCSLNNPPLEMMFDVGKNQPPLMKRAFSTEK", "length": 417 }, "evidence": [ { "id": "F1NG10", "url": "https://omabrowser.org/oma/group/F1NG10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54JY2-1", "protein_name": "Actin-related protein 10", "gene_name": "arpH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKSSIVLEIGGRYTKCGYSPESSPRFIIPTNLLPLNISSYLSGGASFDNFKKEITSDNETITTTNQIPTKLPTQSQLKESLFIFFKTIFLNYLLCKSDERKIIIVENIFLPRLFRESMVSVLFEQYRVPLIVFINPTASLIPTLRTTALLIDSGFSETRVLPIYEGVGILKAYKSISLGSESLINQLKQYLQSNITNGIIIDNQNNQSITDSMICNQLLNDKILNSIQLLEDIITRCCFCSFKNKNNNNIEINNINYRISKEYSILIDGNNIRKGLVDVLYKDVNNNDNNNNNKEDDDENLEEGNIATTILNTLLKCEHDQRKPLSHNILLLGGTTMLAGFKKRLVLELHRQLKMNENSIYRNELFGLIGHFQFINHPFENNYLSWLGGSILANALEHVHSKITLESYLNAPSQFKRSQLIPEWEKLTNINNYTQIAQATMGTTINPLQFNSTSSLFSPFTSSSDLSSHLNKD", "length": 475 }, "evidence": [ { "id": "F1NG10", "url": "https://omabrowser.org/oma/group/F1NG10/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NZ32-1", "protein_name": "Actin-related protein 10", "gene_name": "ACTR10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMPKPVRVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVIIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLLEQCTVDTSVAKEQSLPSVMGSVPEGVLEDIKARTCFVSDLKRGLKIQAAKFNIDGNNERPSPPPNVDYPLDGEKILHILGSIRDSVVEILFEQDNEEQSVATLILDSLIQCPIDTRKQLAENLVVIGGTSMLPGFLHRLLAEIRYLVEKPKYKKALGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGRIPDWCSLNNPPLEMMFDVGKTQPPLMKRAFSTEK", "length": 417 }, "evidence": [ { "id": "F1NG10", "url": "https://omabrowser.org/oma/group/F1NG10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZB7-1", "protein_name": "Actin-related protein 10", "gene_name": "Actr10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKRAGMSKPIKVVQYNINTEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPILNCWGALPLGGKALHKELETQLLEQCTVDTGAAKGQSLPSVMGSVPEGVLEDIKVRTCFVSDLKRGLQIQAAKFNIDGNNERPTPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLLQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKNFRIHTPPAKANCVAWLGGAVFGALQDILGSRSISKEYYNQTGRIPDWCSLNNPPLEMMFDVGKAQPPLMKRAFSTEK", "length": 417 }, "evidence": [ { "id": "F1NG10", "url": "https://omabrowser.org/oma/group/F1NG10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VWE8-1", "protein_name": "Actin-related protein 10, isoform B", "gene_name": "Arp10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPIYESVMQEKPPIVLDIGTAYTKLGFAAEAYPRKIMPTEVVMTTTGIRKRLFDYDTPEELYDQLVDFLQTIFFKHLLVSPKERKFVLVENVFGSTVLRETLARVLFVHFDVSSVLFVPVHLIALSTLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKDQSYGGSAIHAEIKRQLVESGVKESLLTESVLEDIKVRTCFVTTMERAKARANGDENQPTPAPDVDYIVSDNDAVIQVPGLLRESAYEIMFEASNERDSLPHLILRSILDCTLDVRRALVESVFLVGGGSMVQGLLARLRQELQHLLTEDPFYAERFHGELQFKFFNAVGKQNFTAWLGGALCGATDLIQTRSLVKETYLKSEHVPDWSNLCDNRPTGS", "length": 378 }, "evidence": [ { "id": "F1NG10", "url": "https://omabrowser.org/oma/group/F1NG10/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrograde axonal transport of mitochondrion", "id": "GO:0098958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098958", "evidence": [ { "database": "UniProtKB", "id": "F1NG10", "url": "https://www.uniprot.org/uniprotkb/F1NG10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NG10-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 417, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NG10-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NG10" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIK3-1", "uniprot_ac": "F1NIK3", "uniprot_id": "F1NIK3_CHICK", "mass": { "chemical_mass": 40728.0, "monoisotopic_mass": 40728.0 }, "refseq": { "ac": "NP_001025805", "name": "developmentally-regulated GTP-binding protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025805" }, "gene_names": [ { "name": "DRG2", "type": "recommended", "evidence": [ { "id": "F1NIK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ] }, { "name": "DRG2", "type": "synonym", "evidence": [ { "id": "NP_001025805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025805" } ] } ], "protein_names": [ { "name": "Developmentally-regulated GTP-binding protein 2", "type": "recommended", "evidence": [ { "id": "F1NIK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIK3/entry#names_and_taxonomy" } ] }, { "name": "Translation factor GTPase DRG2", "type": "synonym", "evidence": [ { "id": "F1NIK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIK3/entry#names_and_taxonomy" } ] }, { "name": "developmentally-regulated GTP-binding protein 2", "type": "synonym", "evidence": [ { "id": "NP_001025805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025805" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719873.1, HAEK01036856.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_001025805.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025805", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025805" } ] }, { "annotation": "Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3#function" }, { "database": "UniProtKB", "id": "ARBA00057286", "url": "https://www.uniprot.org/uniprotkb/ARBA00057286#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DRG2", "url": "https://www.uniprot.org/uniprotkb/F1NIK3", "locus": { "chromosome": "14", "start_pos": 5018357, "end_pos": 5009047, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017437", "url": "https://www.ensembl.org/id/ENSGALG00010017437" } ] } } ], "crossref": [ { "id": "F1NIK3", "url": "https://alphafold.ebi.ac.uk/entry/F1NIK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004953", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004953", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01896", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01896", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17231", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17231", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416513", "url": "https://www.ncbi.nlm.nih.gov/gene/416513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416513", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVCDQVH", "url": "https://omabrowser.org/oma/group/DVCDQVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2H2", "url": "https://www.orthodb.org/?gene=A0A8V0Z2H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NIK3", "url": "https://www.orthodb.org/?gene=F1NIK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16897", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16897", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9629569", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001025805", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025805", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIK3-1", "url": "https://www.uniprot.org/uniprotkb/F1NIK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSSAAKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVVIMMLDATKGEVQRALLEKELESVGIRLNKSKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARRPHSVVISCGMKLNLDYLLEKLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHMMEHEDVIQIVKK", "length": 364, "header": "tr|F1NIK3-1|F1NIK3_CHICK Isoform 1 of Developmentally-regulated GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=DRG2 PE=1 SV=1 CANONICAL=F1NIK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2H2-1", "url": "https://www.uniprot.org/uniprotkb/F1NIK3/entry#A0A8V0Z2H2-1", "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSSAAKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVVIMMLDATKGEVQRALLEKELESVGIRLNKSKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARRPHSVVISCGMKLNLDYLLEKLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWSDGCCCRRWSGAVDREATVRGL", "length": 358, "header": "tr|A0A8V0Z2H2-1|F1NIK3_CHICK Computationally mapped isoform of Developmentally-regulated GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=DRG2 PE=1 SV=1 CANONICAL=F1NIK3-1" }, "locus": { "chromosome": "14", "start_pos": 5017746, "end_pos": 5009121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042097.1", "url": "https://www.ensembl.org/id/ENSGALT00010042097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024650.1", "url": "https://www.ensembl.org/id/ENSGALP00010024650.1" } ] } }, { "isoform_ac": "F1NIK3-1", "url": "https://www.uniprot.org/uniprotkb/F1NIK3/entry#F1NIK3-1", "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSSAAKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVVIMMLDATKGEVQRALLEKELESVGIRLNKSKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARRPHSVVISCGMKLNLDYLLEKLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHMMEHEDVIQIVKK", "length": 364, "header": "tr|F1NIK3-1|F1NIK3_CHICK Isoform 1 of Developmentally-regulated GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=DRG2 PE=1 SV=1 CANONICAL=F1NIK3-1" }, "locus": { "chromosome": "14", "start_pos": 5016265, "end_pos": 5009121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042093.1", "url": "https://www.ensembl.org/id/ENSGALT00010042093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024647.1", "url": "https://www.ensembl.org/id/ENSGALP00010024647.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416513", "resource": "KEGG Pathway" }, { "id": "R-GGA-9629569", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9629569", "resource": "Reactome", "description": "Protein hydroxylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAI8-1", "protein_name": "Developmentally regulated GTP binding protein 2", "gene_name": "Drg2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGGSRKRDLASVYAIRAALTQPLSRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDDFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVIRQGLCIALADLELTVWRGLALNSYISTCLPSPRTGIKDVHRLQGSVPVRKKALGKPVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK", "length": 364 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GVH4-1", "protein_name": "Developmentally-regulated GTP-binding protein 2", "gene_name": "Drg2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGRGRGRQVIAVARTADVVVMMLDATKGDVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK", "length": 364 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P53295-1", "protein_name": "Ribosome-interacting GTPase 2", "gene_name": "RBG2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGIIDKIKAIEEEMARTQKNKATEHHLGLLKGKLARYRQQLLADEAGSGGGGGSGFEVAKSGDARVVLIGYPSVGKSSLLGKITTTKSEIAHYAFTTLTSVPGVLKYQGAEIQIVDLPGIIYGASQGKGRGRQVVATARTADLVLMVLDATKSEHQRASLEKELENVGIRLNKEKPNIYYKKKETGGVKVTFTSPPKTNLTEQAIKMILRDYRIHNAEVLVRDDQCTIDDFIDVINEQHRNYVKCLYVYNKIDAVSLEEVDKLAREPNTVVMSCEMDLGLQDVVEEIWYQLNLSRVYTKKRGVRPVFDDPLVVRNNSTIGDLCHGIHRDFKDKFKYALVWGSSAKHSPQKCGLNHRIDDEDVVSLFAK", "length": 368 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P55039-1", "protein_name": "Developmentally-regulated GTP-binding protein 2", "gene_name": "DRG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK", "length": 364 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54WT4-1", "protein_name": "Developmentally-regulated GTP-binding protein 2 homolog", "gene_name": "drg2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGILEKIKDIEAEMSRTQKNKATEYHLGLLKAKLARLRQQLLDPPKSSGKGGDGFEVLKSGDARVALIGFPSVGKSTILTKLTETKSLAAAYEFTTLTCIPGVIQHKGARIQLLDTPGIIEGASQGRGRGRQVIAVARTADLILMMLDANKGEIQKRLLQEELESIGIRLNSQPPNIYFKLKSAGGVNLTATQTLTKITEKLAKSILHEYKIFNCDLVIRCDPTVDELIDAIEGRRSYIRCLYVYNKMDHMSMEDVDRLSRQPNSVVISCNMNLNLDFLLDKIWDYLNLVRVYTKLRGASPDFNDAIILREGATMEDICRFLHKELVSQFKYGIVWGVSAKHCPQRVGISHALEDEDVIQIVKK", "length": 364 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q58D56-1", "protein_name": "Developmentally-regulated GTP-binding protein 2", "gene_name": "DRG2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSSSSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVVIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPDSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK", "length": 364 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CAI1-1", "protein_name": "Developmentally-regulated G protein 2", "gene_name": "DRG2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGIVERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGSSGGGDGFEVTKYGHGRVALIGFPSVGKSTLLTMLTGTHSEAASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEGASEGKGRGRQVIAVAKSSDLVLMVLDASKSEGHRQILTKELEAVGLRLNKRPPQIYFKKKKTGGISFNTTTPLTRIDEKLCYQILHEYKIHNAEVLFREDATVDDFIDVVEGNRKYIKCVYVYNKIDVVGIDDVDRLARQPNSIVISCNLKLNLDRLLARMWDEMGLVRVYSKPQSQQPDFDEPFVLSADRGGCTVEDFCNQVHRTLVKDMKYALVWGTSARHYPQHCGLFHHLEDEDVVQIVKKKVREEGGRGRFKSHSNAPARIADREKKAPLKQ", "length": 399 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9QXB9-1", "protein_name": "Developmentally-regulated GTP-binding protein 2", "gene_name": "Drg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGRGRGRQVIAVARTADVVVMMLDATKGDVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDDFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK", "length": 364 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VDV2-1", "protein_name": "Developmentally-regulated GTP-binding protein 2", "gene_name": "Dmel\\CG6195", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGILEKIAEIEREIARTQKNKATEYHLGLLKAKLAKYRSQLLEPSKKGEKGDGFDVLKSGDARVALIGFPSVGKSTMLSTLTKTESEAANYEFTTLTCIPGVIEYQGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADLVLMMLDATKPNVHRELLERELESVGIRLNKRKPNIYFKQKKGGGLSFNATCSLTRCNEKMVQTILHSFKIFNAEVLFREDCTEDEFIDVVTANRVYLPCLYVYNKIDQISIEEVDRLARQPNSIVVSCNMKLNLDYMMEALWEALQLIRVYTKKPGAPPDFDDGLILRKGVSVEHVCHAIHRTLAAQFKYALVWGTSTKYSPQRVGIAHVMADEDVIQVVKK", "length": 363 }, "evidence": [ { "id": "F1NIK3", "url": "https://omabrowser.org/oma/group/F1NIK3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "F1NIK3", "url": "https://www.uniprot.org/uniprotkb/F1NIK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NIK3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 364, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NIK3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NIK3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NKU9-1", "uniprot_ac": "F1NKU9", "uniprot_id": "F1NKU9_CHICK", "mass": { "chemical_mass": 198879.0, "monoisotopic_mass": 198879.0 }, "refseq": { "ac": "XP_003641574", "name": "nebulin-related-anchoring protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641574" }, "gene_names": [ { "name": "NRAP", "type": "recommended", "evidence": [ { "id": "F1NKU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ] }, { "name": "NRAP", "type": "synonym", "evidence": [ { "id": "XP_003641574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641574" } ] } ], "protein_names": [ { "name": "Nebulin related anchoring protein", "type": "synonym", "evidence": [ { "id": "F1NKU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#names_and_taxonomy" } ] }, { "name": "nebulin-related-anchoring protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003641574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641574" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NRAP", "url": "https://www.uniprot.org/uniprotkb/F1NKU9", "locus": { "chromosome": "6", "start_pos": 28244511, "end_pos": 28294908, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019009", "url": "https://www.ensembl.org/id/ENSGALG00010019009" } ] } } ], "crossref": [ { "id": "ENSGALG00000008914", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008914", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423899", "url": "https://www.ncbi.nlm.nih.gov/gene/423899", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055297", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055297", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423899", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NERPYWT", "url": "https://omabrowser.org/oma/group/NERPYWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2H5", "url": "https://www.orthodb.org/?gene=A0A8V0Z2H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2I0", "url": "https://www.orthodb.org/?gene=A0A8V0Z2I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8C4", "url": "https://www.orthodb.org/?gene=A0A8V0Z8C4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z919", "url": "https://www.orthodb.org/?gene=A0A8V0Z919", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z935", "url": "https://www.orthodb.org/?gene=A0A8V0Z935", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Z2", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NKU9", "url": "https://www.orthodb.org/?gene=F1NKU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11039:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11039:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2H5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8C4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z919", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z919", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z919-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z919-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z935", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z935", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z935-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z935-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKU9-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVQPCARCGYGVYPAEKINCIDQTWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPGYQVAKRATQLSSNVEYRRGHEERVSKFTSVVDTPDILHAKAGGQLASDLKYTEDFEEQRGKGSFPAMITPAYQIAKRANELASDVKYHQTYEKEIKGKASHTAGTDVTFTRENVDQYGQDYMNEYEERRGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEKKYRQKVDALKFTSVADSSHIKHAKKSQELQSDVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISESKYRQQPHSFKYTSVTDSPGLLHAKFSNMIANERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVKYKSDLNWLRGIGWTPPGSYKVERARRAAELAYLREMGLQAASAQYGPEADQVGPEGSQQVTVNPDASEILQVKRRKMQLYK", "length": 1736, "header": "tr|F1NKU9-1|F1NKU9_CHICK Isoform 1 of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=2 CANONICAL=F1NKU9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2H5-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#A0A8V0Z2H5-1", "sequence": { "sequence": "MNVQPCARCGYGVYPAEKINCIDQTWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPGYQVAKRATQLSSNVEYRRGHEERVSKFTSVVDTPDILHAKAGGQLASDLKYTEDFEEQRGKGSFPAMITPAYQIAKRANELASDVKYHQTYEKEIKGKASHTAGTDVTFTRENVDQYGQDYMNEYEERRGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISESKYRQQPHSFKYTSVTDSPGLLHAKFSNMIANERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVKYKSDLNWLRGIGWTPPGSYKVERARRAAELAYLREMGLQAASAQYGPEADQVGPEGSQQVTVNPDASEILQVKRRKMQLYK", "length": 1703, "header": "tr|A0A8V0Z2H5-1|F1NKU9_CHICK Computationally mapped isoform of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=1 CANONICAL=F1NKU9-1" }, "locus": { "chromosome": "6", "start_pos": 28289931, "end_pos": 28244844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046015.1", "url": "https://www.ensembl.org/id/ENSGALT00010046015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027415.1", "url": "https://www.ensembl.org/id/ENSGALP00010027415.1" } ] } }, { "isoform_ac": "A0A8V0Z2I0-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#A0A8V0Z2I0-1", "sequence": { "sequence": "MNVQPCARCGYGVYPAEKINCIDQTWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPGYQVAKRATQLSSNVEYRRGHEERVSKFTSVVDTPDILHAKAGGQLASDLKYTEDFEEQRGKGSFPAMITPAYQIAKRANELASDVKYHQTYEKEIKGKASHTAGTDVTFTRENVDQYGQDYMNEYEERRGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEKKYRQKVDALKFTSVADSSHIKHAKKSQELQSDVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVKYKSDLNWLRGIGWTPPGSYKVERARRAAELAYLREMGLQAASAQYGPEADQVGPEGSQQVTVNPDASEILQVKRRKMQLYK", "length": 1703, "header": "tr|A0A8V0Z2I0-1|F1NKU9_CHICK Computationally mapped isoform of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=1 CANONICAL=F1NKU9-1" }, "locus": { "chromosome": "6", "start_pos": 28289931, "end_pos": 28244844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046023.1", "url": "https://www.ensembl.org/id/ENSGALT00010046023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027420.1", "url": "https://www.ensembl.org/id/ENSGALP00010027420.1" } ] } }, { "isoform_ac": "A0A8V0Z8C4-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#A0A8V0Z8C4-1", "sequence": { "sequence": "MNVQPCARCGYGVYPAEKINCIDQTWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPGYQVAKRATQLSSNVEYRRGHEERVSKFTSVVDTPDILHAKAGGQLASDLKYTEDFEEQRGKGSFPAMITPAYQIAKRANELASDVKYHQTYEKEIKGKASHTAGTDVTFTRENVDQYGQDYMNEYEERRGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEKKYRQKVDALKFTSVADSSHIKHAKKSQELQSDVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISESKYRQQPHSFKYTSVTDSPGLLHAKFSNMIANERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVSTAERYCPSQC", "length": 1665, "header": "tr|A0A8V0Z8C4-1|A0A8V0Z8C4_CHICK Computationally mapped isoform of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=1 CANONICAL=F1NKU9-1" }, "locus": { "chromosome": "6", "start_pos": 28289931, "end_pos": 28246177, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046011.1", "url": "https://www.ensembl.org/id/ENSGALT00010046011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027412.1", "url": "https://www.ensembl.org/id/ENSGALP00010027412.1" } ] } }, { "isoform_ac": "A0A8V0Z919-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#A0A8V0Z919-1", "sequence": { "sequence": "MNVQPCARCGYGVYPAEKINCIDQTWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPAYQIAKRANELASDVKYHQTYEKEIKGKASHTAGTDVTFTRENVDQYGQDYMNEYEERRGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEKKYRQKVDALKFTSVADSSHIKHAKKSQELQSDVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISESKYRQQPHSFKYTSVTDSPGLLHAKFSNMIANERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVKYKSDLNWLRGIGWTPPGSYKVERARRAAELAYLREMGLQAASAQYGPEADQVGPEGSQQVTVNPDASEILQVKRRKMQLYK", "length": 1665, "header": "tr|A0A8V0Z919-1|A0A8V0Z919_CHICK Computationally mapped isoform of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=1 CANONICAL=F1NKU9-1" }, "locus": { "chromosome": "6", "start_pos": 28289931, "end_pos": 28244844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046056.1", "url": "https://www.ensembl.org/id/ENSGALT00010046056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027450.1", "url": "https://www.ensembl.org/id/ENSGALP00010027450.1" } ] } }, { "isoform_ac": "A0A8V0Z935-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#A0A8V0Z935-1", "sequence": { "sequence": "MCGETWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPGYQVAKRATQLSSNVEYRRGHEERVSKFTSVVDTPDILHAKAGGQLASDLKYTEDFEEQRGKGSFPAMITPAYQIAKRANELASDVKYHQTYEKEIKGKASHTAGTDVTFTRENVDQYGQDYMNEYEERRGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEKKYRQKVDALKFTSVADSSHIKHAKKSQELQSDVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISESKYRQQPHSFKYTSVTDSPGLLHAKFSNMIANERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVKYKSDLNWLRGIGWTPPGSYKVERARRAAELAYLREMGLQAASAQYGPEADQVGPEGSQQVTVNPDASEILQVKRRKMQLYK", "length": 1716, "header": "tr|A0A8V0Z935-1|A0A8V0Z935_CHICK Computationally mapped isoform of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=1 CANONICAL=F1NKU9-1" }, "locus": { "chromosome": "6", "start_pos": 28294817, "end_pos": 28244844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046072.1", "url": "https://www.ensembl.org/id/ENSGALT00010046072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027466.1", "url": "https://www.ensembl.org/id/ENSGALP00010027466.1" } ] } }, { "isoform_ac": "A0A8V0Z9Z2-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#A0A8V0Z9Z2-1", "sequence": { "sequence": "MNVQPCARCGYGVYPAEKINCIDQTWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEKKYRQKVDALKFTSVADSSHIKHAKKSQELQSDVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISESKYRQQPHSFKYTSVTDSPGLLHAKFSNMIANERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVKYKSDLNWLRGIGWTPPGSYKVERARRAAELAYLREMGLQAASAQYGPEADQVGPEGSQQVTVNPDASEILQVKRRKMQLYK", "length": 1595, "header": "tr|A0A8V0Z9Z2-1|A0A8V0Z9Z2_CHICK Computationally mapped isoform of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=1 CANONICAL=F1NKU9-1" }, "locus": { "chromosome": "6", "start_pos": 28289931, "end_pos": 28244844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046065.1", "url": "https://www.ensembl.org/id/ENSGALT00010046065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027459.1", "url": "https://www.ensembl.org/id/ENSGALP00010027459.1" } ] } }, { "isoform_ac": "F1NKU9-1", "url": "https://www.uniprot.org/uniprotkb/F1NKU9/entry#F1NKU9-1", "sequence": { "sequence": "MNVQPCARCGYGVYPAEKINCIDQTWHKACFHCEVCKMMLTVNNFVSHEKKPYCQVHNPKNNAFTSIFETPINLNAKKLSEVVSEVKYREESEQFKSAFQWDVRSRDIEAAYKAQHLSSQNAYYAAYEGGTSWYSGNMPDPQMVTVTQAQKNLNDLQYTEEYELRQGKGSFPAMITPGYQVAKRATQLSSNVEYRRGHEERVSKFTSVVDTPDILHAKAGGQLASDLKYTEDFEEQRGKGSFPAMITPAYQIAKRANELASDVKYHQTYEKEIKGKASHTAGTDVTFTRENVDQYGQDYMNEYEERRGKGSFPAMITPAYQNAKKANELASDIKYKKDLSKMKGAAHFHSLTAEDNLVLKQAQSANKLVSEVEYKKDLGNNRGYSVNYCDTPQFKNVSKISKYTSDIKYKETYQNQMKGHYMGIGMDKRMLHAMKVGNLASNIAYKSDYKHDGVDYNYPATLTPSYQTTRKLVPLKDVNYRQSIDKMKYSSVASTPEIAQAKINAQQLSDLNYRAQYEKTKTNYTLPQDIPQLVKAKANAELYSEVKYKEGWEKSKGQGFEMKLDSLPLLAAKASRDLASDIKYKEEYEKTKGKAIETKDSRLLHSLQVAKMSSEIAYKKDFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKRLHEYTVVPEDLKTKWAKKAYGLQSDLQYREDLMWMKGVGCITEGSLNIQQAKKAGDLVSEKKYRQKVDALKFTSVADSSHIKHAKKSQELQSDVAYRSGKEQFLHQYTITKDDPVFLLAKANAANISEKLYRSSWEKQKEKGFVLRLDALSFLTAKAKRDLASDIKYKEGYEKMKGKLIGVKAVEEDSKMAHSLQMSKLQSDLEYKKAFEDTKNQFQVSMDMANLVHAKKAQNLASDKGYRTALHHYTVLPTDRKVAWAKWAYGLQSDNRYRADLNWMKGAGWIATGSLNVEQAKKAGELISEKKYRQHPYALKFTSIKDTPEMIQARISYNQAVDRLYKEHGESIKHQYTLTADLPEILRAKLNTMNISEIRYKESWQKMKDGGYQLRLDAIPFQAAKASGEIISDHKYKEAFEKMKGQMIGSCGLDGDIRIAHSVHASSLQSDVKYKQGFEDTKTHFHLPLDMINLVHARKAQSLVSEQEYRQLLHQYTSLTDDLRLQCAKNAYKLQSENLYRSDMNFMRGVGCITPGALEIEGKKKASELISESKYRQQPHSFKYTSVTDSPGLLHAKFSNMIANERLYKAAGEDIQHHYTPTLGLPEFTQARINAANLSDVKYRESWHNLCAQGYKLTMEALPFQTARASREIASDYQYKHNFVMERGKHIGARSVLDDTRLLHCLHAAKLQSEQEYKKGSQGVWSQYYLPMDMVNLVHARKAQALASDQEYRKRLHEFTALPEDLKMKWAKRAHMLQSEHRYKSDLNFMKGVGWMALRSPQIESVKKAGELISETKYRQKPESLKFTAVVDSPDLIHAKNSYLQCNDRLYKAGDSEARHRYTLPPDHPDFIRARQNALNISDKVYKTSWEQTRASGYDFRIDAIPFQTAKASREIASDYKYREAFLRDRGQRIGFFSANDDAHTRHVLRVGKLQSDNLYRSGYAQNRGHFQSHLNQPGFLHAKRSQQLASNVNYKQPLHQYTCDPEQLNVKHAKQAYKLQSDVKYKSDLNWLRGIGWTPPGSYKVERARRAAELAYLREMGLQAASAQYGPEADQVGPEGSQQVTVNPDASEILQVKRRKMQLYK", "length": 1736, "header": "tr|F1NKU9-1|F1NKU9_CHICK Isoform 1 of Nebulin related anchoring protein OS=Gallus gallus OX=9031 GN=NRAP PE=4 SV=2 CANONICAL=F1NKU9-1" }, "locus": { "chromosome": "6", "start_pos": 28289931, "end_pos": 28244844, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046035.1", "url": "https://www.ensembl.org/id/ENSGALT00010046035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027432.1", "url": "https://www.ensembl.org/id/ENSGALP00010027432.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1669, "start_aa": "Thr", "end_pos": 1669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1669", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423899", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423899", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M8J5-1", "protein_name": "Nebulin-related-anchoring protein", "gene_name": "NRAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNVQACSRCGYGVYPAEKINCLDQIWHKACFHCEVCKMMLSVNNFVSYQKKPYCHAHNPKNNTFTSVYYTPLNLNVRKPPEAICGIGGQEDGERFKSVFHWDMKSKDEAAAPNRQPQVDERAYWSGYREGDAWCPGALPDPEIVRMVEARKSLGEEYPEDYEQQRGKGSFPAMITPAYQRAKIANQLASQVEYKRGHDERISRFSTVADTPELLRAKAGGQLQSDVRYTEAYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQREMKGMAGPAAGAEGPLPKEYMDQYGQGYSEEYGEHRGKGSFPAMITPAYQNAKKANELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKRAQSVNKLVSEVEYKKDLESSKGHSINYCETPQFRNVCKISKFTSDNKYKENYQNRMRGRYEGVGMDKRMLHALKVGSLASNIAYKADYKHDVVDYNYPATLTPSYQTTVKLAPLKDVNYRQSIDKLKYSSVTNTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKARTNAELFSEVKYREGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKAKGKVLGTTDSRLLHSLQVAKMSSEVEYKKGFEKSKTHFHLPMDMVNIRHAKKAQALASDLDYRKRLHEYTVLPEDMKTLWAKKAYGLQSELQYKADLAWMKGVRWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVADSSQMEHAKKSQELQSGVAYKAEHEQSVHQYSISKDEPLFLQARANAANLSEKLYKSSWENQKAKAFDLRLDSLAFLAAKAKRDLASEVKYKEDYEKSRGKLIGAQGAQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVPLDMIHLVHARKAQHLATDIGYKTASHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGTGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENLKHHYTQTTDLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDAIPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYASSLQSQVNYKKDFEHSKAQFHLPLDMVTLVHAKKAQTLASDQDYRHPLPQYTSLAEDLRLSCAKRAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKRASELISESKYRQHPQSLKYTAVTDTPSLTHVKLSNQITNERLYKAAGEDARHQYTMTLGLPEFVRAKTNAANLSDAKYKESWRNLHAQGYKLTIDALPFQAARVSGDIASDFLYRHDFVKERGRLIGAQSVSDDPRLQHCQRVGQLQSELQYRRQAAGSRAQCHLPMDMVPLVHARKAQALASDLDYRTQCHAFTALPEDLRMAWAKKAHALQSELRYKSDLMGMKGTGWLALSSPQIESAKKAGELISETKYREKPDTIKFTTVVDSPDLVHAKNSYMHCNERLYRSGDAESRHRYTLVPDHPDFTRARLNALNLSDKVYRHSWEQTRAGGYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSINDDPRTKHFLSVGRLQSDNEYKKDFAKSRSQFHSRPDQPGFLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLKHAQKAHRLQSDVKYKSDLNLTRGIGWTPPGSYKVEMARRAAELANARGLGLQGAYGGPEAVEPRDDQSGFVNPDATEILHVKRRKAPLF", "length": 1730 }, "evidence": [ { "id": "F1NKU9", "url": "https://omabrowser.org/oma/group/F1NKU9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8M9QIV4-1", "protein_name": "Nebulin-related-anchoring protein isoform X1", "gene_name": "nrap", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNVQKCARCGFVVYPAEKVNLIGQNWHKACFHCEVCKMVLTANNYVSHQKRPYCQVHNPKNNTFTSVYETPVNINAKKQSEAVSENKYKEEGERFMSTFHYDMRSKEIEQARKASQLASQQQGYQTEFVGQQSFYSGSVTSQEIVRVSQTQKTISDVEYKRGHETRMLQFTSVADSPEVLHAKTGVSLASDVKYTEEYEQSKGKGSFPAMITPGYEMAKKANTLASNLEYKKGHEERVSKYTTVTDTPDVLLAKTQGKIVSDHVYTEGYEQQRGKGSFPAHFTPGYQVAKKAGDMASKVKYQQKYEQEIKGKASTEAGAAEFALAKENAEHFSQHAYTEEYEQQRGKGSFPAMITPGYQMAKKAHDIASDLKYKKDFNKMKGSSAYHTLTTEDNLALKSARKINKLMSEVEYKKDLETTKGHSINYCETPQFKNVSKIAKYTSDNKYKENYTNHMKGHYEGGGIDKKTMHAMNVRKLASDISYKSEYEQEKNVQGEYNYPANITPSYQSQKKLEPLKDKNYRQHIDKLKFSQVTDTPEIVQARINAHQLSDLNYKANYEKTKTQYTLSQDMPELKKAKANAELVSDIKYKEDWEKNKSKACEIGLDTLTLKAAKASRDLASDIKYKESYTKNKDKAIGMDVSDSKTLHSLQVAKLSSEVAYKKDSKETQSKCHLPQDMVNLSHAKKAQALASDLEYRKKLHDYTLLSDDMKVQQAKKAYKLQSDNQYRSDLNWMKGVGWEADGCLDVEQAKKAGELFSEKKYRQKVDMVKFTQVADTPSIMHAKKSQELQSGLAYKAGTEQTMHQYTISKDEPLFKQAKANAELLSEKTYKSSWDEQREKGFELGLDTLSILSAKATRDLASDVKYKQKYEMTKGKMIGVKTVADDSQMAHSTHATKLHSDLNYKKQYEDTKTKHSASLDMLTLTHAKKAQELATETNYKTFLHKYTILPSDMKLEWAKKAYGLQSDKKYRSDLNWMKGVGWETTGSLDIRQARKATDLASEKKYRQDVSALKFTSVEDTPEMVQAKISSKLVLDRLYREKGENEMHKYTMIGDIPEHVQAKLNAINLSESHYKESWKKIRDGGYKLRLDAIPFQAAKSSAEILSDQKYKAQFEKTKGKMIGLKGLQDDINMAHSVHASSIQSDLKYKKGSSEVHSQFHLPMDMLDVIHAKKAQSLVSDQDYRHTLHKYTTLPDDLKVQAAKRAYELQSEKIYRSDLNYLRGAAWIATGALQIEGSRRATDLISEKKYRQQPYSFKHTSVTDSPDMVHAKTSNKITNERLYKEKGENFRHNYTITAERPEITQAKINAANFSDVKYKESWNVLRAQGYKLTMKDIPFQAAKASTSIASDVQYKHSHALEKGKHIGVRSILEDSHLMHCLEMGRLQSDQHYRKDAMCTSGQYQLPLDMVNLVHAKKAQALASDQDYKTQIHSYTVLPDDIKVQWAKKAYELQSQNVYKSDLNFMKGVAWDSVGAPQLESAKKAGELISDKKYRQNPDSLKFTQVADSPDIIHAKNSYMQCSERMYKSGDSDSMHKYTLHADHPDFIRARINAQQISDKVYKTSGEQVKSAGYDLRLDAIPFQTAKASREIASDFRYKEAFVKDKGHQVGLLSVEDDPKMRHSLAVGKLQSNNEYKKQFKETRSQFKINADLPEFQHAKKSQAQLSNINYRQQLHDYTCDPNQLNVKHAKQAYQLQSDVNYKSDLNWIKGVGWTPPGSLKVEMARRAAELGLAEGVTTDEAIAQYQQLMMLQRQQEFQDQHDSTTEQTETTMETQQPGVNPDAMEILHVKRKKTIHTTFKQAKTTKSITSQSVASHSTTSQSITNQSTKKQSIMSQSHAGESAARHMSENRAITEQADAKAGTM", "length": 1862 }, "evidence": [ { "id": "F1NKU9", "url": "https://omabrowser.org/oma/group/F1NKU9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A4K6-1", "protein_name": "Nebulin-related anchoring protein", "gene_name": "Nrap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNMQACSRCGYGVYPAEKVSCIDQTWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFTSVYRTPLNLTLKNSVAAMGGTDGKEDGEQFKSVLHWDMKSKAGAGAASRLMNERDYWPGYGEGNTWCPGALPDPEIVRMVEARQSLREQGYTEDGEQPQGKGSFPAMITPAYQRAKAANQLASQVQYKRGHDERVSTFTPVADTPELLRANAGGQLQNDVRYTEDGGQQRGKGSFPAMITPAYQIAKRAAELASDVRYHQQYHREMKGVASPVGAEGTMTKDSIDRCGQTYSEECEEHRGKGSFPAMITPAYQNAKKANELASDIKYRQDFHKMKGAAHFHSLAAQDNLVLQRAQNVSKLVSEVEYKKGLENSKGHSINYCETPQFRNVSKISKFTSDNKYKENYQTHLRGHYEGVGMDRRMLHALKVGSLASNVAYKADYKHDVVDYNYPATATPFYQTTMKLAPLKDVNYRQNIDRLKFSSVTNTPQIVQAKINAQQLSHVNYRADYERNKLNYTLPQDAPQMLKAKANAQLFSEVKYKEGWQKTKGKGFEMKLDAMSLLAAKASGELASSIKYKEEYEKTKGRVLGTTDSKLLHSLQVAKMSSEVEYKKGFEESKTHFHLPMDMVNLRHAKKAQALASDLDYRKKLHDYTVLPEDLKTQWAKKAHGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKHYRQKVDELKFTSVTDSSQMEHAKKSQELQNAVAYKAGNEQSVHQYTISKDEPFFLRARANAAQLSETLYKSSWEKQKAKGFELRLDSLTFLTAKAKRDLASEVKYKEDYERSRGKLIGAKSAQGDSQMSHSLQMSKLQSELEYKKGFEDTRSQYHVSLDMIHLAHARQAQHLATDVGYRTASHCFTALPTDMKVEWAKKAYSLQSDNQYRADMKWMKGTGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENLKHHYTQTVDLPEVLLAKLNAMNISETRYKESWSRLRDGGYKLRLDALPFQAAKASSEVISDYKYKEAFERMKGQLLGSRSLEDDLSLAHSVHATSLQSDVNYKKGFEHSKAHFHLPLDMVTLVHAKKAQTLASNQDYRHPLPQHTSLAEDLRLRCAKKAHKLQSENLYRSDLNFMRGVPCVIPGALEIEGRKKASELISESKYRQHPGSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHQYTMTLGLPEFIRAKTNAANLSEAKYKESWHNLRAQGYKLTIDALPFQAARASGDIASDFLYRHEFVKERGQLIGVRSVSDDPRLRHCQRMGQLQSENWYRKEAASSQAQYHLPMDMVPLVHARKAQALASDHDYRTQCHEFTALPEDLKMAWAKKAHALQSEFRYKADLMGMKGSGWLALQSPQIESAKKAGELISETKYREKPDSIKFTTVVDSPDLVHARKSYEHCNERLYRLGDADSLHRYTPIADHPDFTRARLNAMHLSDKVYRNSWEKNRAGGYDFRLDAIPFQTARASRDIASDFRYKEAFLRDRGLQIGYRSVNDDPRMRHFLRVGRLQSDNEYRKDFAKGRSQFHSRPDQPGFLQAKRSQQLASDVLYRQPLPQHTSDPEELGLKHARKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANRRGLGIQGASVETEAVELGDHRSRGVNPDASEILHINRKKTLLM", "length": 1728 }, "evidence": [ { "id": "F1NKU9", "url": "https://omabrowser.org/oma/group/F1NKU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XB4-1", "protein_name": "Nebulin-related-anchoring protein", "gene_name": "Nrap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVQACSRCGYGVYPAEKISCIDQTWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFTSVYHTPLNLTLKKSVAAMGGIDGKEDGEPFKSVLHWDMKSKAGAGAASRLMNERDYWPGYAEGNTWCPGALPDPEIVRMVEARQSLGEGYTEDREQQQGKGSFPAMITPAYQRAKAANQLASQVQYKRGHDERVSTFTPVADTPELLRAKAGGQLQNDVRYTEDGGQQRGKGSFPAMITPAYQIAKRATELASDVRYHQQYHREMKGMASPVGAEGGMTKDSVDRCGQVYSEECDEPRGKGSFPAMITPAYQNAKKANELVSDIKYRQDFHKMKGAAHFHSLAAQDNLVLKRAQSVSKLVSEVEYKKGLENSKGHSINYCETPQFRNVSKISKFTSDNKYKENYQTQLRGHYDGVGMDRRMLHALKVGSLASNVAYKADYKHDVVDYNYLATATPFYQTTMRLVPLKDVNYRQNIDRMKFSSVTNTPQIVQAKINAQQLSHVNYRADYERNKLNYTLPQDAPQLLKAKANAELFSEVKYKEGWQKTKGKGFEMKLDAMSLLAAKASGELASSVKYKEEYEKMKGRALGATDSKLLHSLQVAKMSSEVEYKKGFEESKTHFNLPMDMVNLRHAKKAQALASDLDYRKKLHDYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMRGVGWLTEGSLNLEQAKKAGQLISEKNYRQRVDELKFTSVADSSQMEHAKKSQGLQNAVAYKAGNEQSVHQYTISKDEPLFLRARANAAQLSETLYKSSWEKQKAKGFELRLDSLAFLTAKAKRDLASEVKYKEDYERSRGKLIGAKSAQGDSQMSHSLQMSKLQSDLEYKKGFEDTRSQCHISLDMVHLVHARQAQHLATDVGYRTASHCFTALPTDMKVEWAKKAYGLQSDNQYRADMKWMKGTGWVATGSLHVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENVKHHYTQTADLPEVLLAKLNAMNISETRYKESWSRLRDGGYKLRLDALPFQAAKASSEVISDYKYKEAFERMKGQMLGSRSLEDDLSLAHSVHATSLQSDVNYKKGFEHAKAHFHLPLDMVTLVHAKKAQTLASDQDYRHPLPQHTVLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVPCVVPGTLEIEGRKKASELISESKYRQHPGSFKYTAVTDTPNLLHAKYSNQITNERLYKAAGEDARHQYTMTLGLPEFIRAKTNAANLSEAKYKEAWHNLRAQGYKLTIDALPFQAARASGDIASDFLYRHEFVKERGQLIGVRNVSDDPRLLHCLRMGQLQSENQYRKEAASSQAQCHLPMDMMYLVHARKAQALASDHDYRTQCHEFTALPEDLKMAWAKKAHALQSEFRYKADLMGMKGTGWLALQSPQIESAKKAGDLISETKYRKKPDSIKFTTVVDSPDLIHAKESYMHCNERLYRLGDAASLHRYTPIPDHPDFTRARMNAMHLSDKVYRNAWEQSRAGGYDFRLDAIPFQTARVSRDIASDFRYKEAFLRDRGLQIGYRSISDDPRTTHFLRVGRLQSDNEYRKAFAKGRSQFHSRADQPGFLQAKRSQQLASDVLYRQPLPQHTSDPEQLGLKHARKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANRRGPGIRGASVEPEAAAALGDHQSRGVNPDASEILHIHKKKTLLM", "length": 1728 }, "evidence": [ { "id": "F1NKU9", "url": "https://omabrowser.org/oma/group/F1NKU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86VF7-1", "protein_name": "Nebulin-related-anchoring protein", "gene_name": "NRAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL", "length": 1730 }, "evidence": [ { "id": "F1NKU9", "url": "https://omabrowser.org/oma/group/F1NKU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" }, { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" }, { "name": "vinculin binding", "id": "GO:0017166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017166", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" }, { "name": "fascia adherens", "id": "GO:0005916", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005916", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" }, { "name": "muscle tendon junction", "id": "GO:0005927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005927", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cardiac muscle thin filament assembly", "id": "GO:0071691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071691", "evidence": [ { "database": "UniProtKB", "id": "F1NKU9", "url": "https://www.uniprot.org/uniprotkb/F1NKU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1024, "end_pos": 1026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1267, "end_pos": 1269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1510, "end_pos": 1512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1669 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1024, "end_pos": 1026 }, { "start_pos": 1267, "end_pos": 1269 }, { "start_pos": 1510, "end_pos": 1512 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 523, "end_pos": 525 }, { "start_pos": 781, "end_pos": 783 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLM6-1", "uniprot_ac": "F1NLM6", "uniprot_id": "F1NLM6_CHICK", "mass": { "chemical_mass": 54699.0, "monoisotopic_mass": 54699.0 }, "refseq": { "ac": "XP_015143376", "name": "serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143376" }, "gene_names": [ { "name": "PPP2R5E", "type": "recommended", "evidence": [ { "id": "F1NLM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLM6" } ] }, { "name": "PPP2R5E", "type": "synonym", "evidence": [ { "id": "XP_015143376", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143376" } ] } ], "protein_names": [ { "name": "Protein phosphatase 2 regulatory subunit B'epsilon", "type": "synonym", "evidence": [ { "id": "F1NLM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLM6/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015143376", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143376" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143376" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLM6", "url": "https://www.uniprot.org/uniprotkb/F1NLM6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP2R5E", "url": "https://www.uniprot.org/uniprotkb/F1NLM6", "locus": { "chromosome": "5", "start_pos": 52890111, "end_pos": 52819066, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017701", "url": "https://www.ensembl.org/id/ENSGALG00010017701" } ] } } ], "crossref": [ { "id": "F1NLM6", "url": "https://alphafold.ebi.ac.uk/entry/F1NLM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011840", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011840", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423512", "url": "https://www.ncbi.nlm.nih.gov/gene/423512", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423512", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423512", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z2H9", "url": "https://www.orthodb.org/?gene=A0A8V0Z2H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2Z4", "url": "https://www.orthodb.org/?gene=A0A8V0Z2Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z454", "url": "https://www.orthodb.org/?gene=A0A8V0Z454", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Y6", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Y6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLM6", "url": "https://www.orthodb.org/?gene=F1NLM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10257:SF92", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10257:SF92", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-141444", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-195253", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-196299", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196299", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2467813", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2467813", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2500257", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2500257", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389513", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389513", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663220", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663220", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9648025", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9648025", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015143376", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143376", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Z4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z454", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z454", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z454-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z454-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLM6", "url": "https://www.uniprot.org/uniprotkb/F1NLM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLM6-1", "url": "https://www.uniprot.org/uniprotkb/F1NLM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT", "length": 467, "header": "tr|F1NLM6-1|F1NLM6_CHICK Isoform 1 of Protein phosphatase 2 regulatory subunit B'epsilon OS=Gallus gallus OX=9031 GN=PPP2R5E PE=1 SV=3 CANONICAL=F1NLM6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2H9-1", "url": "https://www.uniprot.org/uniprotkb/F1NLM6/entry#A0A8V0Z2H9-1", "sequence": { "sequence": "MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT", "length": 449, "header": "tr|A0A8V0Z2H9-1|F1NLM6_CHICK Computationally mapped isoform of Protein phosphatase 2 regulatory subunit B'epsilon OS=Gallus gallus OX=9031 GN=PPP2R5E PE=1 SV=1 CANONICAL=F1NLM6-1" }, "locus": { "chromosome": "5", "start_pos": 52888769, "end_pos": 52822925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042792.1", "url": "https://www.ensembl.org/id/ENSGALT00010042792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025282.1", "url": "https://www.ensembl.org/id/ENSGALP00010025282.1" } ] } }, { "isoform_ac": "A0A8V0Z2Z4-1", "url": "https://www.uniprot.org/uniprotkb/F1NLM6/entry#A0A8V0Z2Z4-1", "sequence": { "sequence": "MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYNEKKKEKEREELWKKLEDLELKRGLRRDGIIPT", "length": 462, "header": "tr|A0A8V0Z2Z4-1|A0A8V0Z2Z4_CHICK Computationally mapped isoform of Serine/threonine protein phosphatase 2A regulatory subunit OS=Gallus gallus OX=9031 GN=PPP2R5E PE=1 SV=1 CANONICAL=F1NLM6-1" }, "locus": { "chromosome": "5", "start_pos": 52888769, "end_pos": 52822925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042794.1", "url": "https://www.ensembl.org/id/ENSGALT00010042794.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025284.1", "url": "https://www.ensembl.org/id/ENSGALP00010025284.1" } ] } }, { "isoform_ac": "A0A8V0Z454-1", "url": "https://www.uniprot.org/uniprotkb/F1NLM6/entry#A0A8V0Z454-1", "sequence": { "sequence": "MAEKGHSEKESMYKLKWSENEEEDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT", "length": 438, "header": "tr|A0A8V0Z454-1|A0A8V0Z454_CHICK Computationally mapped isoform of Serine/threonine protein phosphatase 2A regulatory subunit OS=Gallus gallus OX=9031 GN=PPP2R5E PE=1 SV=1 CANONICAL=F1NLM6-1" }, "locus": { "chromosome": "5", "start_pos": 52888769, "end_pos": 52831090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042793.1", "url": "https://www.ensembl.org/id/ENSGALT00010042793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025283.1", "url": "https://www.ensembl.org/id/ENSGALP00010025283.1" } ] } }, { "isoform_ac": "A0A8V0Z9Y6-1", "url": "https://www.uniprot.org/uniprotkb/F1NLM6/entry#A0A8V0Z9Y6-1", "sequence": { "sequence": "MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKGSQLQWFSLKVMCLTPSLVSAGVYGREGPQ", "length": 82, "header": "tr|A0A8V0Z9Y6-1|A0A8V0Z9Y6_CHICK Computationally mapped isoform of Protein phosphatase 2 regulatory subunit B'epsilon OS=Gallus gallus OX=9031 GN=PPP2R5E PE=1 SV=1 CANONICAL=F1NLM6-1" }, "locus": { "chromosome": "5", "start_pos": 52831109, "end_pos": 52822925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042791.1", "url": "https://www.ensembl.org/id/ENSGALT00010042791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025281.1", "url": "https://www.ensembl.org/id/ENSGALP00010025281.1" } ] } }, { "isoform_ac": "F1NLM6-1", "url": "https://www.uniprot.org/uniprotkb/F1NLM6/entry#F1NLM6-1", "sequence": { "sequence": "MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQEFQPSIAKKYIDQKFVLQLLELFDSEDPRERDYLKTVLHRIYGKFLGLRAFIRKQINNIFLRFVYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLVKVLIPLHTVRSLSLFHAQLAYCIVQFLEKDPSLTEPVIRGLMKFWPKTCSQKEVMFLGELEEILDVIEPSQFVKIQEPLFKQIAKCVSSPHFQVAERALYYWNNEYIMSLIEENSNVILPIMFSSLYRISKEHWNPAIVALVYNVLKAFMEMNSTMFDELTATYKSDRQREKKKEKEREELWKKLEDLELKRGLRRDGIIPT", "length": 467, "header": "tr|F1NLM6-1|F1NLM6_CHICK Isoform 1 of Protein phosphatase 2 regulatory subunit B'epsilon OS=Gallus gallus OX=9031 GN=PPP2R5E PE=1 SV=3 CANONICAL=F1NLM6-1" }, "locus": { "chromosome": "5", "start_pos": 52888769, "end_pos": 52822925, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042797.1", "url": "https://www.ensembl.org/id/ENSGALT00010042797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025287.1", "url": "https://www.ensembl.org/id/ENSGALP00010025287.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423512", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423512", "resource": "KEGG Pathway" }, { "id": "R-GGA-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-GGA-141444", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141444", "resource": "Reactome", "description": "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" }, { "id": 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"GO:0072542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072542", "evidence": [ { "database": "UniProtKB", "id": "F1NLM6", "url": "https://www.uniprot.org/uniprotkb/F1NLM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 467, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLM6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 418, "end_pos": 420 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NML9-1", "uniprot_ac": "F1NML9", "uniprot_id": "F1NML9_CHICK", "mass": { "chemical_mass": 53524.0, "monoisotopic_mass": 53524.0 }, "refseq": { "ac": "NP_001384289", "name": "nuclear receptor ROR-alpha isoform 2", "summary": "The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289" }, "gene_names": [ { "name": "RORA", "type": "recommended", "evidence": [ { "id": "F1NML9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ] }, { "name": "RORA", "type": "synonym", "evidence": [ { "id": "NP_001384289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289" } ] }, { "name": "RORalpha1", "type": "synonym", "evidence": [ { "id": "NP_001384289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289" } ] } ], "protein_names": [ { "name": "RAR related orphan receptor A", "type": "synonym", "evidence": [ { "id": "F1NML9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML9/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor ROR-alpha isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001384289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.19521.1, SRR12888497.517198.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Nov 9, 2021 this sequence version replaced XP_015134374.1. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289" } ] }, { "annotation": "RORalpha could negatively regulate green light-enhanced T-lymphocyte proliferation in chick thymus by upregulating IkappaB phosphorylation, which promotes P65 nuclear translocation and NF-kappaB activation.", "evidence": [ { "database": "RefSeq", "id": "NP_001384289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289" }, { "database": "PubMed", "id": "31326445", "url": "https://glygen.org/publication/PubMed/31326445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RORA", "url": "https://www.uniprot.org/uniprotkb/F1NML9", "locus": { "chromosome": "10", "start_pos": 5057364, "end_pos": 4676286, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024646", "url": "https://www.ensembl.org/id/ENSGALG00010024646" } ] } } ], "crossref": [ { "id": "F1NML9", "url": "https://alphafold.ebi.ac.uk/entry/F1NML9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003759", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003759", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06968", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06968", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415377", "url": "https://www.ncbi.nlm.nih.gov/gene/415377", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415377", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415377", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VSMAELX", "url": "https://omabrowser.org/oma/group/VSMAELX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U690", "url": "https://www.orthodb.org/?gene=A0A3Q2U690", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UCE3", "url": "https://www.orthodb.org/?gene=A0A3Q2UCE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYX9", "url": "https://www.orthodb.org/?gene=A0A8V0ZYX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A145", "url": "https://www.orthodb.org/?gene=A0A8V1A145", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NML9", "url": "https://www.orthodb.org/?gene=F1NML9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45805:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45805:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-383280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4090294", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001384289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U690", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U690", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U690-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U690-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UCE3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UCE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UCE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A145", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A145", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A145-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A145-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NML9-1", "url": "https://www.uniprot.org/uniprotkb/F1NML9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCFVLAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNITTNGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAVKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPEVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLIAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 468, "header": "tr|F1NML9-1|F1NML9_CHICK Isoform 1 of RAR related orphan receptor A OS=Gallus gallus OX=9031 GN=RORA PE=3 SV=3 CANONICAL=F1NML9-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U690-1", "url": "https://www.uniprot.org/uniprotkb/F1NML9/entry#A0A3Q2U690-1", "sequence": { "sequence": "MNHFTFGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNITTNGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAVKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPEVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLIAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 474, "header": "tr|A0A3Q2U690-1|A0A3Q2U690_CHICK Computationally mapped isoform of RAR related orphan receptor A OS=Gallus gallus OX=9031 GN=RORA PE=3 SV=1 CANONICAL=F1NML9-1" }, "locus": { "chromosome": "10", "start_pos": 5054395, "end_pos": 4881325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060174.1", "url": "https://www.ensembl.org/id/ENSGALT00010060174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036934.1", "url": "https://www.ensembl.org/id/ENSGALP00010036934.1" } ] } }, { "isoform_ac": "A0A3Q2UCE3-1", "url": "https://www.uniprot.org/uniprotkb/F1NML9/entry#A0A3Q2UCE3-1", "sequence": { "sequence": "MESAPAAPDPAASEPGSSGSEAAAGARDTPVNLEPARKGDAPAPVRRQSYSSGGGRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNITTNGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAVKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPEVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLIAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 524, "header": "tr|A0A3Q2UCE3-1|F1NML9_CHICK Computationally mapped isoform of RAR related orphan receptor A OS=Gallus gallus OX=9031 GN=RORA PE=3 SV=1 CANONICAL=F1NML9-1" }, "locus": { "chromosome": "10", "start_pos": 5054395, "end_pos": 4707965, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060175.1", "url": "https://www.ensembl.org/id/ENSGALT00010060175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036935.1", "url": "https://www.ensembl.org/id/ENSGALP00010036935.1" } ] } }, { "isoform_ac": "A0A8V0ZYX9-1", "url": "https://www.uniprot.org/uniprotkb/F1NML9/entry#A0A8V0ZYX9-1", "sequence": { "sequence": "MQINEGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNITTNGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAVKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPEVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLIAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 473, "header": "tr|A0A8V0ZYX9-1|A0A8V0ZYX9_CHICK Computationally mapped isoform of RAR related orphan receptor A OS=Gallus gallus OX=9031 GN=RORA PE=3 SV=1 CANONICAL=F1NML9-1" }, "locus": { "chromosome": "10", "start_pos": 5054395, "end_pos": 4895819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060172.1", "url": "https://www.ensembl.org/id/ENSGALT00010060172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036932.1", "url": "https://www.ensembl.org/id/ENSGALP00010036932.1" } ] } }, { "isoform_ac": "A0A8V1A145-1", "url": "https://www.uniprot.org/uniprotkb/F1NML9/entry#A0A8V1A145-1", "sequence": { "sequence": "MVVSKQESSYLAEVFFGSNPEESCCCHLNLVPRLKYKIFSFLIISVDCAAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNITTNGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAVKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPEVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLIAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 507, "header": "tr|A0A8V1A145-1|A0A8V1A145_CHICK Computationally mapped isoform of RAR related orphan receptor A OS=Gallus gallus OX=9031 GN=RORA PE=3 SV=1 CANONICAL=F1NML9-1" }, "locus": { "chromosome": "10", "start_pos": 5054395, "end_pos": 4993170, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060169.1", "url": "https://www.ensembl.org/id/ENSGALT00010060169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036929.1", "url": "https://www.ensembl.org/id/ENSGALP00010036929.1" } ] } }, { "isoform_ac": "F1NML9-1", "url": "https://www.uniprot.org/uniprotkb/F1NML9/entry#F1NML9-1", "sequence": { "sequence": "MMCFVLAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNITTNGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAVKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPEVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLIAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 468, "header": "tr|F1NML9-1|F1NML9_CHICK Isoform 1 of RAR related orphan receptor A OS=Gallus gallus OX=9031 GN=RORA PE=3 SV=3 CANONICAL=F1NML9-1" }, "locus": { "chromosome": "10", "start_pos": 5054395, "end_pos": 4992557, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010060167.1", "url": "https://www.ensembl.org/id/ENSGALT00010060167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036927.1", "url": "https://www.ensembl.org/id/ENSGALP00010036927.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Effect of the melatonin nuclear receptor ROR\u03b1 on monochromatic light-induced T-lymphocyte proliferation in chicken thymus.", "journal": "Immunology letters", "date": "2019-09", "authors": "Xiong Juanjuan, Wang Zixu, Cao Jing, Dong Yulan, Chen Yaoxing", "evidence": [ { "database": "RefSeq", "id": "NP_001384289", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384289" } ], "reference": [ { "type": "PubMed", "id": "31326445", "url": "https://glygen.org/publication/PubMed/31326445" } ] } ], "pathway": [ { "id": "gga:415377", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415377", "resource": "KEGG Pathway" }, { "id": "R-GGA-383280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-383280", "resource": "Reactome", "description": "Nuclear Receptor transcription pathway" }, { "id": "R-GGA-4090294", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4090294", "resource": "Reactome", "description": "SUMOylation of intracellular receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZJH8-1", "protein_name": "RAR related orphan receptor A", "gene_name": "RORA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 468 }, "evidence": [ { "id": "F1NML9", "url": "https://omabrowser.org/oma/group/F1NML9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QLY4-1", "protein_name": "Nuclear receptor ROR-alpha A", "gene_name": "roraa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMYFVISAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQQQRDHQQQPGEAEPLTPTYGLSTNGLTELHDDLSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYFDGKYAGPDVFKSLGCDDLISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCSRHTEKLTAFKAIYPDIVRAHFPPLYKELFGSDFEQSMPVDG", "length": 468 }, "evidence": [ { "id": "F1NML9", "url": "https://omabrowser.org/oma/group/F1NML9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 523 }, "evidence": [ { "id": "F1NML9", "url": "https://omabrowser.org/oma/group/F1NML9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51448-1", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "Rora", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESAPAAPDPAASEPGSSGSEAAAGSRETPLTQDTGRKSEAPGAGRRQSYASSSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSTYMDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG", "length": 523 }, "evidence": [ { "id": "F1NML9", "url": "https://omabrowser.org/oma/group/F1NML9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 21, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "positive regulation of vascular endothelial growth factor production", "id": "GO:0010575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010575", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "regulation of glucose metabolic process", "id": "GO:0010906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010906", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "negative regulation of fat cell differentiation", "id": "GO:0045599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045599", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "regulation of smoothened signaling pathway", "id": "GO:0008589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008589", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "muscle cell differentiation", "id": "GO:0042692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042692", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "T-helper 17 cell differentiation", "id": "GO:0072539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072539", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "cerebellar granule cell precursor proliferation", "id": "GO:0021930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021930", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "regulation of steroid metabolic process", "id": "GO:0019218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019218", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "cellular response to sterol", "id": "GO:0036315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036315", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" }, { "name": "positive regulation of circadian rhythm", "id": "GO:0042753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042753", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": "https://www.uniprot.org/uniprotkb/F1NML9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NML9", "url": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1C852-1", "uniprot_ac": "E1C852", "uniprot_id": "E1C852_CHICK", "mass": { "chemical_mass": 35660.0, "monoisotopic_mass": 35660.0 }, "refseq": { "ac": "XP_426503", "name": "PDZ and LIM domain protein 1 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426503" }, "gene_names": [ { "name": "PDLIM1", "type": "recommended", "evidence": [ { "id": "E1C852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ] }, { "name": "PDLIM1", "type": "synonym", "evidence": [ { "id": "XP_426503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426503" } ] } ], "protein_names": [ { "name": "PDZ and LIM domain 1", "type": "synonym", "evidence": [ { "id": "E1C852", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C852/entry#names_and_taxonomy" } ] }, { "name": "PDZ and LIM domain protein 1 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_426503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426503" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_426503.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426503" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDLIM1", "url": "https://www.uniprot.org/uniprotkb/E1C852", "locus": { "chromosome": "6", "start_pos": 17251194, "end_pos": 17212547, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021740", "url": "https://www.ensembl.org/id/ENSGALG00010021740" } ] } } ], "crossref": [ { "id": "E1C852", "url": "https://alphafold.ebi.ac.uk/entry/E1C852", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005422", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005422", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06753", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06753", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09448", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09448", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428948", "url": "https://www.ncbi.nlm.nih.gov/gene/428948", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428948", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428948", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QIYCETH", "url": "https://omabrowser.org/oma/group/QIYCETH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NU14", "url": "https://www.orthodb.org/?gene=A0A1D5NU14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLR0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C852", "url": "https://www.orthodb.org/?gene=E1C852", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15936", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15936", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NU14", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NU14-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NU14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C852-1", "url": "https://www.uniprot.org/uniprotkb/E1C852-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTHRIVLTGPGPWGFRLVGGRDFEQPLTISRVTPGSKAAIANLCIGDQIIAIDGVNTDNMTHLEAQNKIKSCADELTLTVSRTESKVWSPLVNEEGKAHPYKMNLASQPQEIRHIGSAHNRSAVPFTAATASAPKVITAQYNSPAGLYSSENIQTFNSAVESKTSPGPPEPSKLLDQHSHPSGSIAIDRDSEVYKMLQENQESHEPPRQSASFLVLQEILESEEKGDPSKPSGFRSVKAPTTKVAASIGNAQKLPMCDKCGSGIVGVFVKIRDKQRHPECYVCSDCGTNLKQKGHFFVEDQIYCEKHARERVVPPEGYEVVTVFPK", "length": 327, "header": "tr|E1C852-1|E1C852_CHICK Isoform 1 of PDZ and LIM domain 1 OS=Gallus gallus OX=9031 GN=PDLIM1 PE=1 SV=1 CANONICAL=E1C852-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NU14-1", "url": "https://www.uniprot.org/uniprotkb/E1C852/entry#A0A1D5NU14-1", "sequence": { "sequence": "MNSRAARSCAPVVPPRCTGPSVLCSEGSASTARNRPATCSALQNAVTPGSKAAIANLCIGDQIIAIDGVNTDNMTHLEAQNKIKSCADELTLTVSRTESKVWSPLVNEEGKAHPYKMNLASQPQEIRHIGSAHNRSAVPFTAATASAPKVITAQYNSPAGLYSSENIQTFNSAVESKTSPGPPEPSKLLDQHSHPSGSIAIDRDSEVYKMLQENQESHEPPRQSASFLVLQEILESEEKGDPSKPSGFRSVKAPTTKVAASIGNAQKLPMCDKCGSGIVGVFVKIRDKQRHPECYVCSDCGTNLKQKGHFFVEDQIYCEKHARERVVPPEGYEVVTVFPK", "length": 340, "header": "tr|A0A1D5NU14-1|E1C852_CHICK Computationally mapped isoform of PDZ and LIM domain 1 OS=Gallus gallus OX=9031 GN=PDLIM1 PE=1 SV=1 CANONICAL=E1C852-1" }, "locus": { "chromosome": "6", "start_pos": 17249992, "end_pos": 17212763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052842.1", "url": "https://www.ensembl.org/id/ENSGALT00010052842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031748.1", "url": "https://www.ensembl.org/id/ENSGALP00010031748.1" } ] } }, { "isoform_ac": "A0A8V0ZLR0-1", "url": "https://www.uniprot.org/uniprotkb/E1C852/entry#A0A8V0ZLR0-1", "sequence": { "sequence": "MGTHRIVLTGPGPWGFRLVGGRDFEQPLTISRVTPGSKAAIANLCIGDQIIAIDGVNTDNMTHLEAQNKIKSCADELTLTVSRTESKVWSPLVNEEGKAHPYKMNLASQPQQRPTQFPRAFSMTCQPAGLNSRLSPMSAQQAPFASVYNPLQSPSVEARGRHSPGALSSQVRVGPEQLKHAAQACPKSPVEVEVPGLKVLHVQFNSPLQLYSQSNIMDSLQGQISSISPDFPSLDQHSHPSGSIAIDRDSEVYKMLQENQESHEPPRQSASFLVLQEILESEEKGDPSKPSGFRSVKAPTTKVAASIGNAQKLPMCDKCGSGIVGVFVKIRDKQRHPECYVCSDCGTNLKQKGHFFVEDQIYCEKHARERVVPPEGYEVVTVFPK", "length": 385, "header": "tr|A0A8V0ZLR0-1|A0A8V0ZLR0_CHICK Computationally mapped isoform of PDZ and LIM domain 1 OS=Gallus gallus OX=9031 GN=PDLIM1 PE=1 SV=1 CANONICAL=E1C852-1" }, "locus": { "chromosome": "6", "start_pos": 17249992, "end_pos": 17213201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052840.1", "url": "https://www.ensembl.org/id/ENSGALT00010052840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031745.1", "url": "https://www.ensembl.org/id/ENSGALP00010031745.1" } ] } }, { "isoform_ac": "E1C852-1", "url": "https://www.uniprot.org/uniprotkb/E1C852/entry#E1C852-1", "sequence": { "sequence": "MGTHRIVLTGPGPWGFRLVGGRDFEQPLTISRVTPGSKAAIANLCIGDQIIAIDGVNTDNMTHLEAQNKIKSCADELTLTVSRTESKVWSPLVNEEGKAHPYKMNLASQPQEIRHIGSAHNRSAVPFTAATASAPKVITAQYNSPAGLYSSENIQTFNSAVESKTSPGPPEPSKLLDQHSHPSGSIAIDRDSEVYKMLQENQESHEPPRQSASFLVLQEILESEEKGDPSKPSGFRSVKAPTTKVAASIGNAQKLPMCDKCGSGIVGVFVKIRDKQRHPECYVCSDCGTNLKQKGHFFVEDQIYCEKHARERVVPPEGYEVVTVFPK", "length": 327, "header": "tr|E1C852-1|E1C852_CHICK Isoform 1 of PDZ and LIM domain 1 OS=Gallus gallus OX=9031 GN=PDLIM1 PE=1 SV=1 CANONICAL=E1C852-1" }, "locus": { "chromosome": "6", "start_pos": 17249992, "end_pos": 17213201, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052844.1", "url": "https://www.ensembl.org/id/ENSGALT00010052844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031750.1", "url": "https://www.ensembl.org/id/ENSGALP00010031750.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:428948", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428948", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HXY1-1", "protein_name": "PDZ and LIM domain protein 1", "gene_name": "Pdlim1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCTDNMTLTVSRSEQKIWSPLVSEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSSAPRIITNQYNNPTGLYSPENISSFNSAVESKTAGSGEEAKSRHSDQPHPSGSLIIDKESEVYKMLQEKQELNEPPKQSTSFLLLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPMCDRCGTGIVGVFVKLRDHHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARERVTPPEGYDVVTVFPK", "length": 329 }, "evidence": [ { "id": "E1C852", "url": "https://omabrowser.org/oma/group/E1C852/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O00151-1", "protein_name": "PDZ and LIM domain protein 1", "gene_name": "PDLIM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK", "length": 329 }, "evidence": [ { "id": "E1C852", "url": "https://omabrowser.org/oma/group/E1C852/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70400-1", "protein_name": "PDZ and LIM domain protein 1", "gene_name": "Pdlim1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCADNMTLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPSTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPVVQPHPSGSLIIDKDSEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVEDQIYCEKHARERVTPPEGYDVVTVFRE", "length": 327 }, "evidence": [ { "id": "E1C852", "url": "https://omabrowser.org/oma/group/E1C852/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P52944-1", "protein_name": "PDZ and LIM domain protein 1", "gene_name": "Pdlim1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANLCIGDLITAIDGEDTSSMTHLEAQNKIKGCVDNMTLTVSRSEQKIWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAPGTRVITNQYNSPTGLYSSENISNFNNAVESKTSASGEEANSRPSAQPHPSGGLIIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHHRHPECYVCTDCGINLKQKGHFFVGDQIYCEKHARERVTPPEGYDVVTVFPK", "length": 327 }, "evidence": [ { "id": "E1C852", "url": "https://omabrowser.org/oma/group/E1C852/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" }, { "name": "muscle structure development", "id": "GO:0061061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061061", "evidence": [ { "database": "UniProtKB", "id": "E1C852", "url": "https://www.uniprot.org/uniprotkb/E1C852" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C982-1", "uniprot_ac": "E1C982", "uniprot_id": "E1C982_CHICK", "mass": { "chemical_mass": 94323.0, "monoisotopic_mass": 94323.0 }, "refseq": { "ac": "XP_015143171", "name": "apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143171" }, "gene_names": [ { "name": "AREL1", "type": "recommended", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "name": "AREL1", "type": "synonym", "evidence": [ { "id": "XP_015143171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143171" } ] } ], "protein_names": [ { "name": "Apoptosis-resistant E3 ubiquitin protein ligase 1", "type": "recommended", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982/entry#names_and_taxonomy" } ] }, { "name": "Apoptosis-resistant HECT-type E3 ubiquitin transferase 1", "type": "synonym", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982/entry#names_and_taxonomy" } ] }, { "name": "apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015143171", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143171" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143171" } ] }, { "annotation": "E3 ubiquitin-protein ligase that catalyzes 'Lys-11'- or 'Lys-33'-linked polyubiquitin chains, with some preference for 'Lys-33' linkages. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates SEPTIN4, DIABLO/SMAC and HTRA2 in vitro. Modulates pulmonary inflammation by targeting SOCS2 for ubiquitination and subsequent degradation by the proteasome.", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982#function" }, { "database": "UniProtKB", "id": "ARBA00056489", "url": "https://www.uniprot.org/uniprotkb/ARBA00056489#function" }, { "database": "UniProtKB", "id": "A0A1D5NXC7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXC7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AREL1", "url": "https://www.uniprot.org/uniprotkb/E1C982", "locus": { "chromosome": "5", "start_pos": 37516907, "end_pos": 37532550, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005981", "url": "https://www.ensembl.org/id/ENSGALG00010005981" } ] } } ], "crossref": [ { "id": "E1C982", "url": "https://alphafold.ebi.ac.uk/entry/E1C982", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010270", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010270", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423354", "url": "https://www.ncbi.nlm.nih.gov/gene/423354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423354", "url": 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"Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015143171", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143171", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NXC7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NXC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NXC7-1", "url": 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CANONICAL=E1C982-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NXC7-1", "url": "https://www.uniprot.org/uniprotkb/E1C982/entry#A0A1D5NXC7-1", "sequence": { "sequence": 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OX=9031 GN=AREL1 PE=4 SV=1 CANONICAL=E1C982-1" }, "locus": { "chromosome": "5", "start_pos": 37531263, "end_pos": 37517090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014305.1", "url": "https://www.ensembl.org/id/ENSGALT00010014305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008399.1", "url": "https://www.ensembl.org/id/ENSGALP00010008399.1" } ] } }, { "isoform_ac": "E1C982-1", "url": "https://www.uniprot.org/uniprotkb/E1C982/entry#E1C982-1", "sequence": { "sequence": "MFYIIGGITVSVVAFFFTIKFLFELAARIVSFLQHEDRERRGERTIYDYVRGNYLDPRSCKISWDWKDPHEVGHSMAFRVHLFYKNGQPFPAHRPLGLRVHICHVELAIDIPVTQEVLQEPNSNVVKVAFTVRRAGRYEISIKLGGLNVAYSPYYKVFQPGMVVPSKTKIVCHFSTLVLTCGQQHTLQIVPRDEYDNPTSNSVSLIDEHNYSLSIHELGPQEEENSDVVFEKSVVSNRQTCQVFFRFTLHCRGCFHACISYQNQPISNGDFDIIVLSENEKNIVERNVSTSGVSIYFEAYLYEASSYTNTQWHLPPTHLSSSQRRPSTATEDEDEDSPSDSQTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLFTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHSLLESSFKATRNFSVSDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTSQLFTRFSDNNQALVHPNPGRPTYVRLKLYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDVSEMDLVFAEEKYSKTGQLEKVVELVTGGAQVPVTNENKIFYLNLLAQYRLANQVREEVDHFLKGLNELVPENLLAIFDENELELLMCGTGDISVCDFKAHAVVVGGSWHFREKVMRWFWTVVSSFTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHKMLQLAISEGCEGFGML", "length": 823, "header": "tr|E1C982-1|E1C982_CHICK Isoform 1 of Apoptosis-resistant E3 ubiquitin protein ligase 1 OS=Gallus gallus OX=9031 GN=AREL1 PE=4 SV=1 CANONICAL=E1C982-1" }, "locus": { "chromosome": "5", "start_pos": 37531123, "end_pos": 37517090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014310.1", "url": "https://www.ensembl.org/id/ENSGALT00010014310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008400.1", "url": "https://www.ensembl.org/id/ENSGALP00010008400.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423354", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423354", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q7I3-1", "protein_name": "Apoptosis-resistant E3 ubiquitin protein ligase 1", "gene_name": "arel1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRLFLLTFVFCSVSWVFFWEVRWKKGKESQIEEWLQGHGLSEYKYLFEDVQTLEELSLCVLSRLEEVVKEKRHWREIIEAHVQLLRDFAFQEWLCSQSLEHYYHTLKTLGCTNLDDLAQFDSQLQLSLAAWGYYYEDYIKLSTGVRVLQASKGSRDQDYEVQLVHSLAERRLNEKWSFAGALIFGCTIALCFLIRDLMFYVIGGITVSIIAFVFTIKFLCELAARVVSFLQNDDPARHGDRSIYDYVRGNYLDPRSCKVSWDWKEPQEVGQTMSFRVQLFYKNGQPFPAHRPVGLRVNITHIELALEVPVTQEVLQEPESNVVKVAFTVRKAGRYEVAVKLGGLNVAYSPYYKIFQPGTVVPSKTKIAYHFSTLVLTYGQQHTLQIEPRDEYGNPTSNSVSLVDEVNYSVHVHPLGTVEEESSEDFYSTSVSANKPQCQVLMRLTFKKKGCFRACISYRDQPLRNGEFDIIVLSENEKNCVEKNVSTPGISIYFEAYLYNMGTYSSCPWQILASSQLALQRRPSMGEEEEEHDSPVEGQSEKIRKPKKVYCYISPKQFSVKEFYLKIIPWRLFTFRVCPGTKFTYHGPDPVHKYLTLVVDDGIQPPVELSCKDRNIMAATFIRFLHKNIGGSETFQDKVNFFQRELRHIHSKRPRTKTSLKISRHSLLESSLKATRNFSVSDWSKNFEVVFQDEEALDWGGPRREWFELVCKALFDTNNQLFTRFSDNNQGLVHPNAERPPHLRVKMYEFAGRVVGKCLYESALGGSYKQLVRARFTRSFLAQIIGLRMNYKYFETDDEEFYKTKVCFILNNDVSEMDLLFAEEKYSKSGHLEKVVELIPGGAQIAVTNENKNHYLNLLAQYRLASQVREEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDINVQDFKAHAVIVGGSWHFREKVMKWFWAVVSSFTQEELARLLQFTTGSSQLPPGGFNTLCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEELHKLLKLAISEGSEGFGML", "length": 1020 }, "evidence": [ { "id": "E1C982", "url": "https://omabrowser.org/oma/group/E1C982/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8C2QNT2-1", "protein_name": "Apoptosis-resistant E3 ubiquitin protein ligase 1", "gene_name": "Arel1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSCKVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVPRDEYDNPTNNSMSLRDEQNYSLSIHELGAQEEENNEVSFEKSVTSNRQTCQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSENEKSIVERNVSTSGVSIYFEAYLYSPNNYTSTPWHLPPMHTSSSQRRPSTAIEEDDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTSQLFTRFSDTNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKIVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML", "length": 823 }, "evidence": [ { "id": "E1C982", "url": "https://omabrowser.org/oma/group/E1C982/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZVC4-1", "protein_name": "Apoptosis-resistant E3 ubiquitin protein ligase 1", "gene_name": "Arel1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFYVIGGIIVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSCKVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVPRDEYDNPTNNSMSLREEHNYSLSIHELGPQEEENSEVSFEKSVTSNRQTCQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSENEKNIVERNVSTSGVSIYFEAYLYNANSYSSAPWHLPPMHMSSSQRRPSTALEEEEEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTSQLFTRFSDNNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKIVELMTGGAQTPVTNANKTFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML", "length": 823 }, "evidence": [ { "id": "E1C982", "url": "https://omabrowser.org/oma/group/E1C982/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15033-1", "protein_name": "Apoptosis-resistant E3 ubiquitin protein ligase 1", "gene_name": "AREL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFYVIGGITVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSCKVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVPRDEYDNPTNNSMSLRDEHNYTLSIHELGPQEEESTGVSFEKSVTSNRQTFQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSEDEKNIVERNVSTSGVSIYFEAYLYNATNCSSTPWHLPPMHMTSSQRRPSTAVDEEDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTNQLFTRFSDNNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKVVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDISVSDFKAHAVVVGGSWHFREKVMRWFWTVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML", "length": 823 }, "evidence": [ { "id": "E1C982", "url": "https://omabrowser.org/oma/group/E1C982/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CHG5-1", "protein_name": "Apoptosis-resistant E3 ubiquitin protein ligase 1", "gene_name": "Arel1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFYVIGGIIVSVVAFFFTIKFLFELAARVVSFLQNEDRERRGDRTIYDYVRGNYLDPRSCKVSWDWKDPYEVGHSMAFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVDIPVTQEVLQEPNSNVVKVAFTVRKAGRYEITVKLGGLNVAYSPYYKIFQPGMVVPSKTKIVCHFSTLVLTCGQPHTLQIVPRDEYDNPTNNSMSLRDEHSYSLAIHELGPQEEENNEVSFEKSVTSNRQTCQVFLRLTLHSRGCFHACISYQNQPINNGEFDIIVLSENEKNIVERNVSTSGVSIYFEAYLYNANNCTSTPWHLPPMHMSSSQRRPSTAIEEDDEDSPSECHTPEKVKKPKKVYCYVSPKQFSVKEFYLKIIPWRLYTFRVCPGTKFSYLGPDPVHKLLTLVVDDGIQPPVELSCKERNILAATFIRSLHKNIGGSETFQDKVNFFQRELRQVHMKRPHSKVTLKVSRHALLESSLKATRNFSISDWSKNFEVVFQDEEALDWGGPRREWFELICKALFDTTSQLFARFTDSNQALVHPNPNRPAHLRLKMYEFAGRLVGKCLYESSLGGAYKQLVRARFTRSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEMELVFAEEKYNKSGQLDKIVELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENELELLMCGTGDINVSDFKAHAVVVGGSWHFREKVMRWFWAVVSSLTQEELARLLQFTTGSSQLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEGFGML", "length": 823 }, "evidence": [ { "id": "E1C982", "url": "https://omabrowser.org/oma/group/E1C982/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQ67-1", "protein_name": "HECT-type E3 ubiquitin transferase", "gene_name": "Dmel\\CG4238", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQMHCSPEDASLRSDLVLIRSFVVYKGRPPDHATRFDISMLVSHINVGGVMHAATGGKTFPTLKVKLCFGESMGISSLSSCGDPERLPELPPLDEQRLQRAALHLQQKLILREWLKDHRLQHHYQRLLAVEVASLEDVYWLEDSRASKILGKDWQLWSGARQNLPTSKAQLDALKAQLWSTVVKSSQHQDAWTWGGMLVVSVSVAGLVTLAAMTQPSLAPEARHSLLQYVTGKYLLPANCKVQWDWKDPASVGGTMCFVVRFFQRNGQPYPICDTDHFFVEVTEGTRKVVTISELGSSTDPNNANIAKVKFTVRTAGQYKISVLIGASHIAGSPFLRSFLPGAIDARRSRFIRPASTVICCAGAPTLMHIEPRDEFGNSCLFDQNQSDEALQGYQVAIYDLHGVPVEKLQHAIVFAYDKVNSRVSVTALFPEPTCLRAVISYRDQQLPNGDFDIIVLSSSDTTLVHKNIASRKHNICYEAKLLSIFGVSKNKPRKVLCYVGPKQNSLIFQVTIKEMILKFIPKRIATFRLCPSTKFHFLPQLVSQLHGPVFIIDDGAQPKIELASKDRNIIAATFTHFLLKNIGGSETFKDKQDFFYHEVRKFHASYYHEKMALKVQREKILESSMKAVKGFSVSDWCGNFEVTFQGEQGIDWGGLRREWFELVCSALFDARGGLFCTFHDKHQALVHPNPTRPAHLKLKHFEFAGKMVGKCLFESALGGTYRQLVRARFSRSFLAQLIGLRVHYKYFEQDDPDLYLSKIKYILDTDLDATDTLELYFVEEMYDSSSGQLSKTIELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLSIFDENELELLMCGTGEYSISDFKAHHIANGNSAEFRRVLAWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQELNPQFQITAAPTFGNLPTAHTCFNQLCLPDYESYEQFEKSLLLAISEGSEGFGMV", "length": 977 }, "evidence": [ { "id": "E1C982", "url": "https://omabrowser.org/oma/group/E1C982/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" }, { "name": "protein K11-linked ubiquitination", "id": "GO:0070979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070979", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" }, { "name": "protein K33-linked ubiquitination", "id": "GO:1990390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990390", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "E1C982", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 483, "end_pos": 823, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.26", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.26", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.26" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 481, "end_pos": 483 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHR2-1", "uniprot_ac": "F1NHR2", "uniprot_id": "F1NHR2_CHICK", "mass": { "chemical_mass": 40447.0, "monoisotopic_mass": 40447.0 }, "refseq": { "ac": "NP_989899", "name": "vascular endothelial growth factor D precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989899" }, "gene_names": [ { "name": "VEGFD", "type": "recommended", "evidence": [ { "id": "F1NHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHR2" } ] }, { "name": "FIGF", "type": "synonym", "evidence": [ { "id": "NP_989899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989899" } ] }, { "name": "VEGFD", "type": "synonym", "evidence": [ { "id": "NP_989899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989899" } ] } ], "protein_names": [ { "name": "Vascular endothelial growth factor D", "type": "recommended", "evidence": [ { "id": "F1NHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#names_and_taxonomy" } ] }, { "name": "c-Fos-induced growth factor", "type": "synonym", "evidence": [ { "id": "F1NHR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#names_and_taxonomy" } ] }, { "name": "c-fos induced growth factor (vascular endothelial growth factor D)", "type": "synonym", "evidence": [ { "id": "NP_989899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989899" } ] }, { "name": "vascular endothelial growth factor D precursor", "type": "synonym", "evidence": [ { "id": "NP_989899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989899" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01003428.1, HAEL01008586.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000022.1. On Jan 4, 2015 this sequence version replaced NP_989899.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_989899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989899" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHR2", "url": "https://www.uniprot.org/uniprotkb/F1NHR2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VEGFD", "url": "https://www.uniprot.org/uniprotkb/F1NHR2", "locus": { "chromosome": "1", "start_pos": 122184374, "end_pos": 122149438, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001454", "url": "https://www.ensembl.org/id/ENSGALG00010001454" } ] } } ], "crossref": [ { "id": "F1NHR2", "url": "https://alphafold.ebi.ac.uk/entry/F1NHR2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016558", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016558", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00135", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00135", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395255", "url": "https://www.ncbi.nlm.nih.gov/gene/395255", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395255", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395255", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IDMLWDN", "url": "https://omabrowser.org/oma/group/IDMLWDN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PSS5", "url": "https://www.orthodb.org/?gene=A0A1D5PSS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RNL9", "url": "https://www.orthodb.org/?gene=A0A1L1RNL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X2G6", "url": "https://www.orthodb.org/?gene=A0A8V0X2G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X8J9", "url": "https://www.orthodb.org/?gene=A0A8V0X8J9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0X8K3", "url": "https://www.orthodb.org/?gene=A0A8V0X8K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XB96", "url": "https://www.orthodb.org/?gene=A0A8V0XB96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NHR2", "url": "https://www.orthodb.org/?gene=F1NHR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12025:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12025:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-194313", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-194313", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-195399", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PSS5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PSS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RNL9", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RNL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RNL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RNL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X2G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8J9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8J9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8J9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8J9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0X8K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XB96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHR2", "url": "https://www.uniprot.org/uniprotkb/F1NHR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHR2-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYKPWVTVNIFMISFLHLLQGSDYENGSVKRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKVIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLPPLAELAMCGQYMEFDEENCECICRQKCPTDFFQSKENCSCYLCRENQESCAQKHKIFHAETCSCEDKCPSQPRTCPTAKPTCPRHCRCPKEKRNSHGSQSKENP", "length": 353, "header": "tr|F1NHR2-1|F1NHR2_CHICK Isoform 1 of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=2 CANONICAL=F1NHR2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PSS5-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#A0A1D5PSS5-1", "sequence": { "sequence": "MMDARFPGEQGQRDCGPHLSVSSSGWDRRDWGVSIPSYMGTNLSSWSNFRYHQKQRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKVIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLPPLAELAMCGQYMEFDEENCECICRQKCPTDFFQSKENCSCYLCRENQESCAQKHKIFHAETCSCEDKCPSQPRTCPTAKPTCPRHCRCPKEKRNSHGSQSKENP", "length": 378, "header": "tr|A0A1D5PSS5-1|F1NHR2_CHICK Computationally mapped isoform of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=1 CANONICAL=F1NHR2-1" }, "locus": { "chromosome": "1", "start_pos": 122180862, "end_pos": 122166257, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003352.1", "url": "https://www.ensembl.org/id/ENSGALT00010003352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001795.1", "url": "https://www.ensembl.org/id/ENSGALP00010001795.1" } ] } }, { "isoform_ac": "A0A1L1RNL9-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#A0A1L1RNL9-1", "sequence": { "sequence": "MSQMRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKVIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLPPLAELAMCGQYMEFDEENCECICRQKCPTDFFQSKENCSCYLCRENQESCAQKHKIFHAETCSCEDKCPSQPRTCPTAKPTCPRHCRCPKEKRNSHGSQSKENP", "length": 327, "header": "tr|A0A1L1RNL9-1|A0A1L1RNL9_CHICK Computationally mapped isoform of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=2 CANONICAL=F1NHR2-1" }, "locus": { "chromosome": "1", "start_pos": 122180862, "end_pos": 122165979, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003351.1", "url": "https://www.ensembl.org/id/ENSGALT00010003351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001794.1", "url": "https://www.ensembl.org/id/ENSGALP00010001794.1" } ] } }, { "isoform_ac": "A0A8V0X2G6-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#A0A8V0X2G6-1", "sequence": { "sequence": "MRPRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKVIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLPPLAELAMCGQYMEFDEENCECICRQKCPTDFFQSKENCSCYLCRENQESCAQKHKIFHAETCSCEDKCPSQPRTCPTAKPTCPRHCRCPKEKRNSHGSQSKENP", "length": 326, "header": "tr|A0A8V0X2G6-1|A0A8V0X2G6_CHICK Computationally mapped isoform of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=1 CANONICAL=F1NHR2-1" }, "locus": { "chromosome": "1", "start_pos": 122180862, "end_pos": 122153960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003358.1", "url": "https://www.ensembl.org/id/ENSGALT00010003358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001801.1", "url": "https://www.ensembl.org/id/ENSGALP00010001801.1" } ] } }, { "isoform_ac": "A0A8V0X8J9-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#A0A8V0X8J9-1", "sequence": { "sequence": "MYKPWVTVNIFMISFLHLLQGSDYENGSVKRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKVIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLVLILNQIIWPSSKVVKLKLGFPLKKELVHHISEYVQRTLNSQ", "length": 290, "header": "tr|A0A8V0X8J9-1|A0A8V0X8J9_CHICK Computationally mapped isoform of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=1 CANONICAL=F1NHR2-1" }, "locus": { "chromosome": "1", "start_pos": 122177923, "end_pos": 122150238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003355.1", "url": "https://www.ensembl.org/id/ENSGALT00010003355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001798.1", "url": "https://www.ensembl.org/id/ENSGALP00010001798.1" } ] } }, { "isoform_ac": "A0A8V0X8K3-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#A0A8V0X8K3-1", "sequence": { "sequence": "MYKPWVTVNIFMISFLHLLQGSDYENGSVKRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKELLCKCTHSWHNSRKMDCNGSESNFLDRSCSLSFINMMKGGRQEKKFLNFKADLKLIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLPPLAELAMCGQYMEFDEENCECICRQKCPTDFFQSKENCSCYLCRENQESCAQKHKIFHAETCSCEDKCPSQPRTCPTAKPTCPRHCRCPKEKRNSHGSQSKENP", "length": 408, "header": "tr|A0A8V0X8K3-1|A0A8V0X8K3_CHICK Computationally mapped isoform of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=1 CANONICAL=F1NHR2-1" }, "locus": { "chromosome": "1", "start_pos": 122180862, "end_pos": 122150238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003360.1", "url": "https://www.ensembl.org/id/ENSGALT00010003360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001803.1", "url": "https://www.ensembl.org/id/ENSGALP00010001803.1" } ] } }, { "isoform_ac": "A0A8V0XB96-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#A0A8V0XB96-1", "sequence": { "sequence": "MYKPWVTVNIFMISFLHLLQGSDYENGSVKRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKVIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLPPLAELAMCGQYMEFDEENCECICRQKCPTDFFQSKENCSCYLCRENQESCAQKHKIFHAETCRESKSTLCSL", "length": 321, "header": "tr|A0A8V0XB96-1|A0A8V0XB96_CHICK Computationally mapped isoform of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=1 CANONICAL=F1NHR2-1" }, "locus": { "chromosome": "1", "start_pos": 122179671, "end_pos": 122150238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003361.1", "url": "https://www.ensembl.org/id/ENSGALT00010003361.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001804.1", "url": "https://www.ensembl.org/id/ENSGALP00010001804.1" } ] } }, { "isoform_ac": "F1NHR2-1", "url": "https://www.uniprot.org/uniprotkb/F1NHR2/entry#F1NHR2-1", "sequence": { "sequence": "MYKPWVTVNIFMISFLHLLQGSDYENGSVKRTSLSALERSEQQIRRASSLEELLRITHAEDWKLWKCRLKLKSLANLDSRSASHRSTRFAAAFYDIDTLKVIDEEWQKTQCVPRETCVEVAKELGTTTNKFFKPPCVNVFRCGGCCNEESLSCMNTSTTYVSKTLFEISVPLTSVPEPVPIKIANHTGCKCLSNTQRHQYTIIRRSVQYPEEDGCPFTNKLCHNGWVWDSDKCECVADVQHSNRREGLPPLAELAMCGQYMEFDEENCECICRQKCPTDFFQSKENCSCYLCRENQESCAQKHKIFHAETCSCEDKCPSQPRTCPTAKPTCPRHCRCPKEKRNSHGSQSKENP", "length": 353, "header": "tr|F1NHR2-1|F1NHR2_CHICK Isoform 1 of Vascular endothelial growth factor D OS=Gallus gallus OX=9031 GN=VEGFD PE=3 SV=2 CANONICAL=F1NHR2-1" }, "locus": { "chromosome": "1", "start_pos": 122180862, "end_pos": 122150238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010003362.1", "url": "https://www.ensembl.org/id/ENSGALT00010003362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001805.1", "url": "https://www.ensembl.org/id/ENSGALP00010001805.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395255", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395255", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-GGA-194313", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-194313", "resource": "Reactome", "description": "VEGF ligand-receptor interactions" }, { "id": "R-GGA-195399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195399", "resource": "Reactome", "description": "VEGF binds to VEGFR leading to receptor dimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SQU4-1", "protein_name": "Vascular endothelial growth factor D", "gene_name": "VEGFD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYRQWAVVNIFMMSSLHLVQGFSYERGPVKRASRSMLERSEQQIRAASGLEELLQITHFEDWKLWRCRLKVKSLASADSRSASHRATRFAATFYDIETLKVIDEEWQRTQCSPRETCVEVASEVGRSTDTFFKPPCVNVFRCGGCCNEESLVCVNTSTSYVSKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPHHPYSIIRRSIQIPEEDGCSHSKKLCPIDMLWDSNKCKCVLQEENPLAGMEDHAHLQELALCGPHMKFDEDRCECVCKMPCPRDFIQHPENCSCIECRETVESCCQKHKIFHPDTCSCEDRCPFHTRTCTNGKPACPKHCRFPKEKRATHGRHDQENP", "length": 354 }, "evidence": [ { "id": "F1NHR2", "url": "https://omabrowser.org/oma/group/F1NHR2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35251-1", "protein_name": "Vascular endothelial growth factor D", "gene_name": "Vegfd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYGEWAAVNILMMSYVYLVQGFSIEHRAVKDVSLERSSRSVLERSEQQIRAASTLEELLQVAHSEDWKLWRCRLKLKSLANVDSRSTSHRSTRFAATFYDTETLKVIDEEWQRTQCSPRETCVEVASELGKTTNTFFKPPCVNVFRCGGCCNEESVMCMNTSTSYISKQLFEISVPLTSVPELVPVKIANHTGCKCLPTGPRHPYSIIRRSIQIPEEDQCPHSKKLCPVDMLWDNTKCKCVLQDENPLPGTEDHSYLQEPALCGPHMMFDEDRCECVCKAPCPGDLIQHPENCSCFECKESLESCCQKHKMFHPDTCRSMVFSLSP", "length": 326 }, "evidence": [ { "id": "F1NHR2", "url": "https://omabrowser.org/oma/group/F1NHR2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43915-1", "protein_name": "Vascular endothelial growth factor D", "gene_name": "VEGFD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYREWVVVNVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSEDWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETCCQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP", "length": 354 }, "evidence": [ { "id": "F1NHR2", "url": "https://omabrowser.org/oma/group/F1NHR2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97946-1", "protein_name": "Vascular endothelial growth factor D", "gene_name": "Vegfd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYGEWGMGNILMMFHVYLVQGFRSEHGPVKDFSFERSSRSMLERSEQQIRAASSLEELLQIAHSEDWKLWRCRLKLKSLASMDSRSASHRSTRFAATFYDTETLKVIDEEWQRTQCSPRETCVEVASELGKTTNTFFKPPCVNVFRCGGCCNEEGVMCMNTSTSYISKQLFEISVPLTSVPELVPVKIANHTGCKCLPTGPRHPYSIIRRSIQTPEEDECPHSKKLCPIDMLWDNTKCKCVLQDETPLPGTEDHSYLQEPTLCGPHMTFDEDRCECVCKAPCPGDLIQHPENCSCFECKESLESCCQKHKIFHPDTCSCEDRCPFHTRTCASRKPACGKHWRFPKETRAQGLYSQENP", "length": 358 }, "evidence": [ { "id": "F1NHR2", "url": "https://omabrowser.org/oma/group/F1NHR2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "F1NHR2", "url": "https://www.uniprot.org/uniprotkb/F1NHR2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "F1NHR2", "url": "https://www.uniprot.org/uniprotkb/F1NHR2" } ], "pmid": "" }, { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "F1NHR2", "url": "https://www.uniprot.org/uniprotkb/F1NHR2" } ], "pmid": "" }, { "name": "response to hypoxia", "id": "GO:0001666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001666", "evidence": [ { "database": "UniProtKB", "id": "F1NHR2", "url": "https://www.uniprot.org/uniprotkb/F1NHR2" } ], "pmid": "" }, { "name": "vascular endothelial growth factor receptor signaling pathway", "id": "GO:0048010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048010", "evidence": [ { "database": "UniProtKB", "id": "F1NHR2", "url": "https://www.uniprot.org/uniprotkb/F1NHR2" } ], "pmid": "" }, { "name": "sprouting angiogenesis", "id": "GO:0002040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002040", "evidence": [ { 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This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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{ "sequence": "MAVLAPLLALLYSVPGLCRWLARPYYPLSALLATAFLLVRKVPPLCRGLPSQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFSDKTIDEELERDKRVTWIVEFFANWSSECQSFAPIFADLSLKYNCSGLHFGKVDVGRYTDVSTRYKIDKKGRAVSWTFSEENVIREFNLNELYQKAKKQSKPRDEGSEEPPEGQAAAGLANGETKKEK", "length": 269, "header": "tr|A0A8V1ACX3-1|A0A8V1ACX3_CHICK Computationally mapped isoform of Thioredoxin related transmembrane protein 2 OS=Gallus gallus OX=9031 GN=TMX2 PE=1 SV=1 CANONICAL=E1C8J7-1" }, "locus": { "chromosome": "5", "start_pos": 16533511, "end_pos": 16531469, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063787.1", "url": "https://www.ensembl.org/id/ENSGALT00010063787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039336.1", "url": "https://www.ensembl.org/id/ENSGALP00010039336.1" } ] } }, { "isoform_ac": "E1C8J7-1", "url": "https://www.uniprot.org/uniprotkb/E1C8J7/entry#E1C8J7-1", "sequence": { "sequence": "MAVLAPLLALLYSVPGLCRWLARPYYPLSALLATAFLLVRKVPPLCRGLPSQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFSDKTIDEELERDKRVTWIVEFFANWSSECQSFAPIFADLSLKYNCSGLHFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGTEIMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQKAKKQSKPRDEGSEEPPEGQAAAGLANGETKKEK", "length": 296, "header": "tr|E1C8J7-1|E1C8J7_CHICK Isoform 1 of Thioredoxin related transmembrane protein 2 OS=Gallus gallus OX=9031 GN=TMX2 PE=1 SV=1 CANONICAL=E1C8J7-1" }, "locus": { "chromosome": "5", "start_pos": 16533511, "end_pos": 16531469, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063783.1", "url": "https://www.ensembl.org/id/ENSGALT00010063783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039335.1", "url": "https://www.ensembl.org/id/ENSGALP00010039335.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428853", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428853", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q2TBU2-1", "protein_name": "Thioredoxin-related transmembrane protein 2", "gene_name": "TMX2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVLAPLIALVYSVPRLSRWLARPYYFLSALLSAAFLLVRKLPPVCESLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFSDKTIDEELERDKRVTWIVEFFANWSSDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEVMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDKIPEEQPVAAVPAAVPDEESKKDK", "length": 296 }, "evidence": [ { "id": "E1C8J7", "url": "https://omabrowser.org/oma/group/E1C8J7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XIK2-1", "protein_name": "Thioredoxin-related transmembrane protein 2", "gene_name": "Tmx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVLAPLIALVYSVPRLSRWLARPYCLLSALLSIAFLLVRKLPPICNGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEVMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKGGDMSEEKPGNPTPTAVPDGENKKDK", "length": 295 }, "evidence": [ { "id": "E1C8J7", "url": "https://omabrowser.org/oma/group/E1C8J7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IQC7-1", "protein_name": "Thioredoxin-related transmembrane protein 2-B", "gene_name": "tmx2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLTPLFAFLYHLPQVYKWLLKPYYIASLFMSIAFVMIRKMPGVCEHLSTQREDGNSCDFDWREVEILMFLSAIVMMKNRRAITIEQHVGNIILFCKVANVILFFRLDIRLGLLYLTLCIVFLMTCKPPLYMGPEYIKYFSDKTIDEELEKDHRVTWIVEFFANWSPECQSFASVYADLSLKYNCAGLKFGKVDIGRYGEVSKKYRVSTSPLSKQLPSLVLFQGGKEVMRRPQVDKKGRAVSWTFTEENIIREFNLNELYQKSKKLGKTKEKLERPSELVFSTVPEEEEPEAETISAMDTESKKDK", "length": 307 }, "evidence": [ { "id": "E1C8J7", "url": "https://omabrowser.org/oma/group/E1C8J7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "disulfide oxidoreductase activity", "id": "GO:0015036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015036", "evidence": [ { "database": "UniProtKB", "id": "E1C8J7", "url": "https://www.uniprot.org/uniprotkb/E1C8J7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1C8J7", "url": "https://www.uniprot.org/uniprotkb/E1C8J7" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "E1C8J7", "url": "https://www.uniprot.org/uniprotkb/E1C8J7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1C8J7", "url": "https://www.uniprot.org/uniprotkb/E1C8J7" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "E1C8J7", "url": "https://www.uniprot.org/uniprotkb/E1C8J7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "brain development", "id": "GO:0007420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007420", "evidence": [ { "database": "UniProtKB", "id": "E1C8J7", "url": "https://www.uniprot.org/uniprotkb/E1C8J7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 185, "end_pos": 187 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSF6-1", "uniprot_ac": "F1NSF6", "uniprot_id": "F1NSF6_CHICK", "mass": { "chemical_mass": 404841.0, "monoisotopic_mass": 404841.0 }, "refseq": { "ac": "NP_001186345", "name": "ubiquitin carboxyl-terminal hydrolase 34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186345" }, "gene_names": [ { "name": "USP34", "type": "recommended", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ] }, { "name": "USP34", "type": "synonym", "evidence": [ { "id": "NP_001186345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186345" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase 34", "type": "recommended", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6/entry#names_and_taxonomy" } ] }, { "name": "Deubiquitinating enzyme 34", "type": "synonym", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase 34", "type": "synonym", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-specific-processing protease 34", "type": "synonym", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 34", "type": "synonym", "evidence": [ { "id": "NP_001186345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186345" } ] }, { "name": "ubiquitin specific protease 34", "type": "synonym", "evidence": [ { "id": "NP_001186345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186345" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000059.1. On or before Dec 17, 2020 this sequence version replaced XP_025004385.1, NP_001186345.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001186345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186345" } ] }, { "annotation": "Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6#function" }, { "database": "UniProtKB", "id": "ARBA00053751", "url": "https://www.uniprot.org/uniprotkb/ARBA00053751#function" }, { "database": "UniProtKB", "id": "A0A3Q2TX44", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TX44#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP34", "url": "https://www.uniprot.org/uniprotkb/F1NSF6", "locus": { "chromosome": "3", "start_pos": 2282626, "end_pos": 2423308, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019302", "url": "https://www.ensembl.org/id/ENSGALG00010019302" } ] } } ], "crossref": [ { "id": "ENSGALG00000004455", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02659", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02659", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421193", "url": "https://www.ncbi.nlm.nih.gov/gene/421193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021905", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021905", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421193", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421193", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TX44", "url": "https://www.orthodb.org/?gene=A0A3Q2TX44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSF6", "url": "https://www.orthodb.org/?gene=F1NSF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-201681", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201681", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TX44", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TX44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TX44-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TX44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSF6-1", "url": "https://www.uniprot.org/uniprotkb/F1NSF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCESCAELLEVLNEISDVEGADGLQLRKEHVLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCTLINLVIAEVQALRDQLCKHCTINIDSTWQDHSNRADEPLNVERDSHEEENGERQRSIEKKIDSARTCILTEESSAKNTDAFSWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISAQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQTAARNMADLMWSTVKEPLDTALCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVIEHIFGPNIHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSTLHPSAHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLSTNLPIGNKKEEDLRRAAPSPWSPAASPQSSDNSDTHQSGGSDIEMEEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEANSSHASQSAESPGSEVQSEDIADIEALKEEEDEEEEDRNHNPQKNSRSTDIRSRKLESQTDICLGDSQGVSERSSTNNGTGKDHVFNTDSVTPVDNRIRILDACSHAEDADHDMTGEMSTAHISQGSQDSCITHTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQYNSSAVTDINLDNVCKKGNTLLWDLVQDEDAIHLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLANNRSVVVSLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVHYIQTVREGRHKYALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSTYDGGSNSELCGMDQFWGIALRAHTGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSNLEQDSHSSLTIIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRIVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGDFPGGLMGPVRMISSGHELTTDYDEKTLHELGFKDMQMVFVSLGAPRRERKGDGVQLPASCLPPPQKDNIPMLLLLQDPHLTTLFDLLEMLASFKPPSGEVSMEDTESAKCEELHLHAENLSRRVWELLMLLPTCPNMLQAFQNISDEQGNDGFSWKDLLRIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQIENSKNTWSCKFVAAGGLQQLLEIFNSGILEPKERESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGVAESHRKRTWPGKSRKTASDHVKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVTHYSMWLLVSWAHCCSSVKSSLADSDYLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIQIEDYEEEPVLRPGCKEYFWLLCKLIDNIHVKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLLHNWVMAQHMQSSHAPYKWDYWPHDDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAIFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKNDRKEGFKEDGEYLKETESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSTQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEENGKDYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWHLCSSIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDCSDDMDGPVEDIGSRSCVTRFVKTLLSIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALIALLVEQSRSERHLTLSQNDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCVDCPENVRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFVAQRPDMREEETEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENLKLIGGKSNIRPPRPELNMCLLPTMVEASKGKDDVYDRMLLDYFFSYHQFIHLLCRVAISCEKFTETLVKMSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNSVKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFLTHFLLKVQGQVFSEANCANLINTLIANLINQYQSLESDFSSQRVEISKASSALNGDLRALALLLSVHTPKQLNSALIPTLQELLNKCRACQQQRNSLQEQEAKERKIKDDEEATPVKRRRVSSDEEHTVDSCISDIKTEPQGALTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDIMLTMRPQHTEEQSGNGKFQECKEFKDLQTSKDSIVTEEDSEFPSTSISAVLSDLADLRGCDSQALSSQDPETSLSITCGHSRGLFSLMQQHDILDILCRTIESTIHVVTRISGKGNQAAS", "length": 3549, "header": "tr|F1NSF6-1|F1NSF6_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Gallus gallus OX=9031 GN=USP34 PE=1 SV=3 CANONICAL=F1NSF6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TX44-1", "url": "https://www.uniprot.org/uniprotkb/F1NSF6/entry#A0A3Q2TX44-1", "sequence": { "sequence": "MCESCAELLEVLNEISDVEGADGLQLRKEHVLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCTLINLVIAEVQALRDQLCKHCTINIDSTWQDHSNRADEPLNVERDSHEEENGERQRSIEKKIDSARTCILTEESSAKNTDAFSWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISAQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQTAARNMADLMWSTVKEPLDTALCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVIEHIFGPNIHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSTLHPSAHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLSTNLPIGNKKEEDLRRAAPSPWSPAASPQSSDNSDTHQSGGSDIEMEEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEANSSHASQSAESPGSEVQSEDIADIEALKEEEDEEEEDRNHNPQKNSRSTDIRSRKLESQTDICLGDSQGVSERSSTNNGTGKDHVFNTDSVTPVDNRIRILDACSHAEDADHDMTGEMSTAHISQGSQDSCITHTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQYNSSAVTDINLDNVCKKGNTLLWDLVQDEDAIHLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLANNRSVVVSLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVHYIQTVREGRHKYALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSTYDGGSNSELCGMDQFWGIALRAHTGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSNLEQDSHSSLTIIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRIVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGDFPGGLMGPVRMISSGHELTTDYDEKTLHELGFKDMQMVFVSLGAPRRERKGDGVQLPASCLPPPQKDNIPMLLLLQDPHLTTLFDLLEMLASFKPPSGEVSMEDTESAKCEELHLHAENLSRRVWELLMLLPTCPNMLQAFQNISDEQGNDGFSWKDLLRIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQIENSKNTWSCKFVAAGGLQQLLEIFNSGILEPKERESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGVAESHRKRTWPGKSRKTASDHVKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVTHYSMWLLVSWAHCCSSVKSSLADSDYLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIQIEDYEEEPVLRPGCKEYFWLLCKLIDNIHVKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLLHNWVMAQHMQSSHAPYKWDYWPHDDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAIFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKNDRKEGFKEDGEYLKETESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSTQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEENGKDYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWHLCSSIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDCSDDMDGPVEDIGSRSCVTRFVKTLLSIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALIALLVEQSRSERHLTLSQNDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCVDCPENVRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFVAQRPDMREEETEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENLKLIGGKSNIRPPRPELNMCLLPTMVEASKVQWSQGHTECRHSPSGHCYSERIQSPAHGVCVHVDGNLCGQHISKKHGYCRGKDDVYDRMLLDYFFSYHQFIHLLCRVAISCEKFTETLVKMSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNSVKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFLTHFLLKVQGQVFSEANCANLINTLIANLINQYQSLESDFSSQRVEISKASSALNGDLRALALLLSVHTPKQLNSALIPTLQELLNKCRACQQQRNSLQEQEAKERKIKDDEEATPVKRRRVSSDEEHTVDSCISDIKTEPQGALTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDIMLTMRPQHTEEQSGNGKFQECKEFKDLQTSKDSIVTEEDSEFPSTSISAVLSDLADLRGCDSQALSSQDPETSLSITCGHSRGLFSLMQQHDILDILCRTIESTIHVVTRISGKGNQAAS", "length": 3600, "header": "tr|A0A3Q2TX44-1|F1NSF6_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 34 OS=Gallus gallus OX=9031 GN=USP34 PE=1 SV=1 CANONICAL=F1NSF6-1" }, "locus": { "chromosome": "3", "start_pos": 2423220, "end_pos": 2283293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046696.1", "url": "https://www.ensembl.org/id/ENSGALT00010046696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027808.1", "url": "https://www.ensembl.org/id/ENSGALP00010027808.1" } ] } }, { "isoform_ac": "F1NSF6-1", "url": "https://www.uniprot.org/uniprotkb/F1NSF6/entry#F1NSF6-1", "sequence": { "sequence": "MCESCAELLEVLNEISDVEGADGLQLRKEHVLKIFAYINSWTQRQCLCCFKEYKHLEIFNQVVCTLINLVIAEVQALRDQLCKHCTINIDSTWQDHSNRADEPLNVERDSHEEENGERQRSIEKKIDSARTCILTEESSAKNTDAFSWSTDEKEKLLLCVAKIFQIQFPLYTAYKHNTHPTIEDISAQESNILGAFCDMNDVEVPLHLLRYVCLFCGKNGLSLMKDCFEYGTPETLPFLIAHAFITVVSNIRIWLHIPAVMQHIIPFRTYVIRYLCKLSDQELRQTAARNMADLMWSTVKEPLDTALCFDKESLDLAFKYFMSPTLTMRLAGLSQITNQLHTFNDVCNNESLVSDTETSIAKELADWLISNNVIEHIFGPNIHIEIIKQCQVILNFLAAEGRLSTQHIDCIWAAAQLKHCSRYIHDLFPSLIKNLDPVPLRHLLNLVSTLHPSAHTEQTLYLASMLIKALWNNALAAKAQLSKQSSFASLLSTNLPIGNKKEEDLRRAAPSPWSPAASPQSSDNSDTHQSGGSDIEMEEQLINRTKHVQQRLSDTEESMQGSSDETANSGEDGSSGPGSSSGHSDGSSNEANSSHASQSAESPGSEVQSEDIADIEALKEEEDEEEEDRNHNPQKNSRSTDIRSRKLESQTDICLGDSQGVSERSSTNNGTGKDHVFNTDSVTPVDNRIRILDACSHAEDADHDMTGEMSTAHISQGSQDSCITHTGDFLGETIGNELFNCRQFIGPQHHHHHHHHHHHHDGHMVDDMLSADDVSCSSSQVSAKSEKNMADFDGEESGCEEELVQINSHAELTSHLQQHLPNLASIYHEHLSQGPAVHKHQYNSSAVTDINLDNVCKKGNTLLWDLVQDEDAIHLSEGLINEAEKLLCSLVCWFTDRQIRMRFIEGCLENLANNRSVVVSLRLLPKLFGTFQQFGSSYDTHWITMWAEKELNMMKLFFDNLVHYIQTVREGRHKYALYSHSAEVQVRLQFLTCVFSTLGSPDHFRLSLEQVDILWHCLVEDSECYDDALHWFLNQVRSKDQHAMGMETYKHLFLEKMPQLKPETISMTGLNLFQHLCNLARLATSTYDGGSNSELCGMDQFWGIALRAHTGDVSRAAIQYINSYYINGKTGLEKEQEFISKCMESLMIASSNLEQDSHSSLTIIERGLLMLKTHLEAFRRRFAYHLRQWQIEGTGISSHLKALSDKQSLPLRIVCQPAGLPDKMTIEMYPSDQVADLRAEVTHWYENLQKEQINQQAQLQEFGQSSRKGDFPGGLMGPVRMISSGHELTTDYDEKTLHELGFKDMQMVFVSLGAPRRERKGDGVQLPASCLPPPQKDNIPMLLLLQDPHLTTLFDLLEMLASFKPPSGEVSMEDTESAKCEELHLHAENLSRRVWELLMLLPTCPNMLQAFQNISDEQGNDGFSWKDLLRIKSAHKLLYALEIIEALGKPNRRIRRESTGSYSDLYPDSDDSSEDQIENSKNTWSCKFVAAGGLQQLLEIFNSGILEPKERESWTVWQLDCLACLLKLICQFAVDPSDLDLAYHDVFAWSGVAESHRKRTWPGKSRKTASDHVKGLHIPRLTEVFLVLVQGTSLIQRLMSVAYTYDNLAPRVLKAQSDHRSRHEVTHYSMWLLVSWAHCCSSVKSSLADSDYLQDWLKKLTLLIPETAVRHESCNGLYKLSLSGLDGGDSINRSFLLLAASTLLKFLPDAQALKPIQIEDYEEEPVLRPGCKEYFWLLCKLIDNIHVKDASQTTLLDLDALARHLADCIRSREILDHQDGNIEDDGLTGLLRLATSVIKHKPPFKFSREGQEFLRDIFNLLFLLPSLKDRQQPKCKSHSSRAAAYDLLVEMVKGSVENYRLLHNWVMAQHMQSSHAPYKWDYWPHDDVRAECRFVGLTNLGATCYLASTIQQLYMIPEARQAIFTAKYSEDMKHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEMSPELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVADMKNIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDMTPYTEDFLMGKNDRKEGFKEDGEYLKETESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSTQLASECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEPEEENGKDYKFDVSSELLEWIWHDNMQFLQDKNIFEHTYFGFMWHLCSSIPSTLPDPKAVSLMTAKLSTSFVLETFIHSKEKPTMLQWIELLTKQFNNSQAACEWFLDRMADDDWWPMQILIKCPNQIVRQMFQRLCIHVIQRLRPVHAHLYLQPGMEDCSDDMDGPVEDIGSRSCVTRFVKTLLSIMEHGVKPHSKHLTEYFAFLYEFAKMGEEESQFLLSLQAISTMVHFYMGTKGPENPQVEVLSEEEGEEEEEEEDILSLAEEKYRPAALEKMIALIALLVEQSRSERHLTLSQNDMAALTGGKGFPFLFQHIRDGINIRQTCNLIFSLCRYNNRLAEHIVSMLFTSIAKLTPEAANPFFKLLTMLMEFAGGPPGMPPFASYILQRIWEVIEYNPSQCLDWLAVQTPRNKLAHSWVLQNMENWVERFLLAHNYPRVRTSAAYLLVSLIPSNSFRQMFRSTRSLHIPTRDLPLSPDTTVVLHQVYNVLLGLLSRAKLYVDAAVHGTTKLVPYFSFMTYCLISKTEKLMFSTYFMDLWNLFQPKLSEPAIATNHNKQALLSFWYNVCVDCPENVRLIVQNPVVTKNIAFNYILADHDDQDVVLFNRGMLPAYYGILRLCCEQSPAFTRQLASHQNIQWAFKNLTPHASQYPGAVEELFNLMQLFVAQRPDMREEETEDIKQFKKTTISCYLRCLDGRSCWTTLISAFRILLESDEDRLLVVFNRGLILMTESFNTLHMMYHEATACHVTGDLVELLSIFLSVLKSTRPYLQRKDVKQALIQWQERIEFAHKLLTLLNSYSPPELRNACIDVLKELVLLSPHDFLHTLVPFLQHNHCTYHHSNIPMSLGPYFPCRENLKLIGGKSNIRPPRPELNMCLLPTMVEASKGKDDVYDRMLLDYFFSYHQFIHLLCRVAISCEKFTETLVKMSVLVAYEGLPLHLALFPKLWTELCQTQSAMSKNSVKLLCEDPVFAEYIKCILMDERTFLNNNIVYTFLTHFLLKVQGQVFSEANCANLINTLIANLINQYQSLESDFSSQRVEISKASSALNGDLRALALLLSVHTPKQLNSALIPTLQELLNKCRACQQQRNSLQEQEAKERKIKDDEEATPVKRRRVSSDEEHTVDSCISDIKTEPQGALTPTSTSDNETRDSSIIDPGTEQDLPSPENSSVKEYRMEVPSSFSEDIMLTMRPQHTEEQSGNGKFQECKEFKDLQTSKDSIVTEEDSEFPSTSISAVLSDLADLRGCDSQALSSQDPETSLSITCGHSRGLFSLMQQHDILDILCRTIESTIHVVTRISGKGNQAAS", "length": 3549, "header": "tr|F1NSF6-1|F1NSF6_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 34 OS=Gallus gallus OX=9031 GN=USP34 PE=1 SV=3 CANONICAL=F1NSF6-1" }, "locus": { "chromosome": "3", "start_pos": 2423220, "end_pos": 2283293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046703.1", "url": "https://www.ensembl.org/id/ENSGALT00010046703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027812.1", "url": "https://www.ensembl.org/id/ENSGALP00010027812.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:421193", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421193", "resource": "KEGG Pathway" }, { "id": "R-GGA-201681", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201681", "resource": "Reactome", "description": "TCF dependent signaling in response to WNT" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" }, { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "F1NSF6", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1389, "end_pos": 1391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1413, "end_pos": 1415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1692, "end_pos": 1694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2338, "end_pos": 2340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2885, "end_pos": 2887, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3390, "end_pos": 3392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3411, "end_pos": 3413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 843, "end_pos": 845, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-3640872", "name": "USP34 deubiquitinates AXIN1,AXIN2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XF27-1", "A0A8V0XC69-1", "F1NSF6-1", "A0A8V0ZDP8-1" ], "evidence": [ { "id": "R-GGA-3640872", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3640872" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XC69", "gene_name": "RNF146", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XC69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XC69" } ] } ] }, { "uniprot_ac": "A0A8V0XF27", "gene_name": "TNKS", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "A0A8V0XF27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XF27" } ] } ] }, { "uniprot_ac": "A0A8V0ZDP8", "gene_name": "TNKS2", "activity": [ { "ec_number": "2.4.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZDP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDP8" } ] } ] }, { "uniprot_ac": "F1NSF6", "gene_name": "USP34", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "F1NSF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSF6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1389, "end_pos": 1391 }, { "start_pos": 1413, "end_pos": 1415 }, { "start_pos": 1692, "end_pos": 1694 }, { "start_pos": 2338, "end_pos": 2340 }, { "start_pos": 2885, "end_pos": 2887 }, { "start_pos": 3390, "end_pos": 3392 }, { "start_pos": 3411, "end_pos": 3413 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 843, "end_pos": 845 }, { "start_pos": 914, "end_pos": 916 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NAZ1-1", "uniprot_ac": "F1NAZ1", "uniprot_id": "F1NAZ1_CHICK", "mass": { "chemical_mass": 66808.0, "monoisotopic_mass": 66808.0 }, "refseq": { "ac": "XP_004937330", "name": "E3 ubiquitin-protein ligase RNF180 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937330" }, "gene_names": [ { "name": "RNF180", "type": "recommended", "evidence": [ { "id": "F1NAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ] }, { "name": "RNF180", "type": "synonym", "evidence": [ { "id": "XP_004937330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937330" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF180", "type": "recommended", "evidence": [ { "id": "F1NAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "F1NAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1/entry#names_and_taxonomy" } ] }, { "name": "E3 ubiquitin-protein ligase RNF180 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_004937330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937330" } ] }, { "name": "RING finger protein 180", "type": "synonym", "evidence": [ { "id": "F1NAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase RNF180", "type": "synonym", "evidence": [ { "id": "F1NAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937330" } ] }, { "annotation": "E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2.", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1#function" }, { "database": "UniProtKB", "id": "ARBA00058659", "url": "https://www.uniprot.org/uniprotkb/ARBA00058659#function" }, { "database": "UniProtKB", "id": "A0A8V0YAT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT8#function" }, { "database": "UniProtKB", "id": "A0A3Q2U4J1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4J1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF180", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1", "locus": { "chromosome": "Z", "start_pos": 20679815, "end_pos": 20603874, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011419", "url": "https://www.ensembl.org/id/ENSGALG00010011419" } ] } } ], "crossref": [ { "id": "F1NAZ1", "url": "https://alphafold.ebi.ac.uk/entry/F1NAZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014743", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014743", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16554", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16554", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101747752", "url": "https://www.ncbi.nlm.nih.gov/gene/101747752", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747752", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2U4J1", "url": "https://www.orthodb.org/?gene=A0A3Q2U4J1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YAT8", "url": "https://www.orthodb.org/?gene=A0A8V0YAT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NAZ1", "url": "https://www.orthodb.org/?gene=F1NAZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46717", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46717", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46717:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46717:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19332", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19332", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U4J1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U4J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YAT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTYRAEESQVEMSIQETDVLRCWRCRKYIANSVCLAKCYGKEPSDISQHSAVARESCNVWHVSLEAIPEWVKCIIEKAQWTVGKLHCPFCEARLGGFNFVCNTKCSCGQLVNIHFCKSRTDYQAACSVKLAKSAGKCLPLCESKSGFSKGSHHEVVMAVSDISPQELSYITRKNNNDTERFTEALCLEARSPRFVMESKKFPLKALNQKRNLLASCLNDACTLKPFHRRSHSLDLNIRERLALSPVLFETSSVGPVYHMKWSNGQNENPSLYTQNDLQLESDNSAFQVQYTSSAGKLQKSFRALSCTTLVHRDTDSDECDFEATGQSSGNAIADGSPFLMNISSSTSAVEEEQYIAPVSPVQSTGISFNQNLSKREKNKLKSMRRKQRRREQWLQKQTANDNLHTDDEPELRGDKESYLCAVCLDVYFNPYMCYPCNHIFCEPCLRMLAKDNPASTPCPLCRTTIARVFFQTELNNSTKSFFPTEYLKLQESFQKSNSAKWPLPSCKKAFRVFEAGFRRRSDTGQVTRRHFPHAAHRMDYMDFEDDSRGWRFDMDMVIIYIYSINWVIGFIVFCFLCYFFFPF", "length": 583, "header": "tr|F1NAZ1-1|F1NAZ1_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF180 OS=Gallus gallus OX=9031 GN=RNF180 PE=4 SV=3 CANONICAL=F1NAZ1-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U4J1-1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1/entry#A0A3Q2U4J1-1", "sequence": { "sequence": "MSSCCCAAPSPPASAASPPPRSFEQRGPTYRAEESQVEMSIQETDVLRCWRCRKYIANSVCLAKCYGKEPSDISQHSAVARESCNVWHVSLEAIPEWVKCIIEKAQWTVGKLHCPFCEARLGGFNFVCNTKCSCGQLVNIHFCKSRTDYQAACSVKLAKSAGKCLPLCESKSGFSKGSHHEVVMAVSDISPQELSYITRKNNNDTERFTEALCLEARSPRFVMESKKFPLKALNQKRNLLASCLNDACTLKPFHRRSHSLDLNIRERLALSPVLFETSSVGPVYHMKWSNGQNENPSLYTQNDLQLESDNSAFQVQYTSSAGKLQKSFRALSCTTLVHRDTDSDECDFEATGQSSGNAIADGSPFLMNISSSTSAVEEEQYIAPVSPVQSTGISFNQNLSKREKNKLKSMRRKQRRREQWLQKQTANDNLHTDDEPELRGDKESYLCAVCLDVYFNPYMCYPCNHIFCEPCLRMLAKDNPASTPCPLCRTTIARVFFQTELNNSTKSFFPTEYLKLQESFQKSNSAKWPLPSCKKAFRVFEGFRRRSDTGQVTRRHFPHAAHRMDYMDFEDDSRGWRFDMDMVIIYIYSINWVIGFIVFCFLCYFFFPF", "length": 609, "header": "tr|A0A3Q2U4J1-1|F1NAZ1_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase RNF180 OS=Gallus gallus OX=9031 GN=RNF180 PE=4 SV=1 CANONICAL=F1NAZ1-1" }, "locus": { "chromosome": "Z", "start_pos": 20676771, "end_pos": 20604053, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027298.1", "url": "https://www.ensembl.org/id/ENSGALT00010027298.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015552.1", "url": "https://www.ensembl.org/id/ENSGALP00010015552.1" } ] } }, { "isoform_ac": "A0A8V0YAT8-1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1/entry#A0A8V0YAT8-1", "sequence": { "sequence": "MSIQETDVLRCWRCRKYIANSVCLAKCYGKEPSDISQHSAVARESCNVWHVSLEAIPEWVKCIIEKAQWTVGKLHCPFCEARLGGFNFVCNTKCSCGQLVNIHFCKSRTDYQAACSVKLAKSAGKCLPLCESKSGFSKGSHHEVVMAVSDISPQELSYITRKNNNDTERFTEALCLEARSPRFVMESKKFPLKALNQKRNLLASCLNDACTLKPFHRRSHSLDLNIRERLALSPVLFETSSVGPVYHMKWSNGQNENPSLYTQNDLQLESDNSAFQVQYTSSAGKLQKSFRALSCTTLVHRDTDSDECDFEATGQSSGNAIADGSPFLMNISSSTSAVEEEQYIAPVSPVQSTGISFNQNLSKREKNKLKSMRRKQRRREQWLQKQTANDNLHTDDEPELRGDKESYLCAVCLDVYFNPYMCYPCNHIFCEPCLRMLAKDNPASTPCPLCRTTIARVFFQTELNNSTKSFFPTEYLKLQESFQKSNSAKWPLPSCKKAFRVFEGFRRRSDTGQVTRRHFPHAAHRMDYMDFEDDSRGWRFDMDMVIIYIYSINWVIGFIVFCFLCYFFFPF", "length": 571, "header": "tr|A0A8V0YAT8-1|F1NAZ1_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase RNF180 OS=Gallus gallus OX=9031 GN=RNF180 PE=4 SV=1 CANONICAL=F1NAZ1-1" }, "locus": { "chromosome": "Z", "start_pos": 20676771, "end_pos": 20609466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027299.1", "url": "https://www.ensembl.org/id/ENSGALT00010027299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015553.1", "url": "https://www.ensembl.org/id/ENSGALP00010015553.1" } ] } }, { "isoform_ac": "F1NAZ1-1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1/entry#F1NAZ1-1", "sequence": { "sequence": "MTYRAEESQVEMSIQETDVLRCWRCRKYIANSVCLAKCYGKEPSDISQHSAVARESCNVWHVSLEAIPEWVKCIIEKAQWTVGKLHCPFCEARLGGFNFVCNTKCSCGQLVNIHFCKSRTDYQAACSVKLAKSAGKCLPLCESKSGFSKGSHHEVVMAVSDISPQELSYITRKNNNDTERFTEALCLEARSPRFVMESKKFPLKALNQKRNLLASCLNDACTLKPFHRRSHSLDLNIRERLALSPVLFETSSVGPVYHMKWSNGQNENPSLYTQNDLQLESDNSAFQVQYTSSAGKLQKSFRALSCTTLVHRDTDSDECDFEATGQSSGNAIADGSPFLMNISSSTSAVEEEQYIAPVSPVQSTGISFNQNLSKREKNKLKSMRRKQRRREQWLQKQTANDNLHTDDEPELRGDKESYLCAVCLDVYFNPYMCYPCNHIFCEPCLRMLAKDNPASTPCPLCRTTIARVFFQTELNNSTKSFFPTEYLKLQESFQKSNSAKWPLPSCKKAFRVFEAGFRRRSDTGQVTRRHFPHAAHRMDYMDFEDDSRGWRFDMDMVIIYIYSINWVIGFIVFCFLCYFFFPF", "length": 583, "header": "tr|F1NAZ1-1|F1NAZ1_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF180 OS=Gallus gallus OX=9031 GN=RNF180 PE=4 SV=3 CANONICAL=F1NAZ1-1" }, "locus": { "chromosome": "Z", "start_pos": 20676771, "end_pos": 20605710, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010027305.1", "url": "https://www.ensembl.org/id/ENSGALT00010027305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015559.1", "url": "https://www.ensembl.org/id/ENSGALP00010015559.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:101747752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747752", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "serotonin metabolic process", "id": "GO:0042428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042428", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" }, { "name": "norepinephrine metabolic process", "id": "GO:0042415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042415", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "F1NAZ1", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NAZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAZ1" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 462, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 475, "end_pos": 477 }, { "start_pos": 476, "end_pos": 478 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NKR7-1", "uniprot_ac": "F1NKR7", "uniprot_id": "F1NKR7_CHICK", "mass": { "chemical_mass": 23667.0, "monoisotopic_mass": 23667.0 }, "refseq": { "ac": "NP_001073210", "name": "stAR-related lipid transfer protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073210" }, "gene_names": [ { "name": "STARD4", "type": "recommended", "evidence": [ { "id": "F1NKR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ] }, { "name": "STARD4", "type": "synonym", "evidence": [ { "id": "NP_001073210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073210" } ] } ], "protein_names": [ { "name": "START domain containing 4, sterol regulated", "type": "synonym", "evidence": [ { "id": "NP_001073210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073210" } ] }, { "name": "StAR related lipid transfer domain containing 4", "type": "synonym", "evidence": [ { "id": "F1NKR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKR7/entry#names_and_taxonomy" } ] }, { "name": "StAR-related lipid transfer (START) domain containing 4", "type": "synonym", "evidence": [ { "id": "NP_001073210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073210" } ] }, { "name": "stAR-related lipid transfer protein 4", "type": "synonym", "evidence": [ { "id": "NP_001073210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073210" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720217.1, SRR13267649.165684.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000095.1. On Sep 23, 2021 this sequence version replaced NP_001073210.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001073210", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073210" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STARD4", "url": "https://www.uniprot.org/uniprotkb/F1NKR7", "locus": { "chromosome": "Z", "start_pos": 47192331, "end_pos": 47183482, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008197", "url": "https://www.ensembl.org/id/ENSGALG00010008197" } ] } } ], "crossref": [ { "id": "F1NKR7", "url": "https://alphafold.ebi.ac.uk/entry/F1NKR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000241", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000241", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08902", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08902", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769322", "url": "https://www.ncbi.nlm.nih.gov/gene/769322", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769322", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769322", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TTQYEEG", "url": "https://omabrowser.org/oma/group/TTQYEEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U505", "url": "https://www.orthodb.org/?gene=A0A3Q2U505", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NKR7", "url": "https://www.orthodb.org/?gene=F1NKR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47006:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47006:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196108", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196108", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001073210", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2U505", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U505", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U505-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U505-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKR7-1", "url": "https://www.uniprot.org/uniprotkb/F1NKR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLPDPAPLATRLQNTLLRYHSIADSEWRIARKTKDAVVWRKPSEEFSGYLYKAQGVVEDITNRIVDHIRPGPYRLDWDSLMTTMDIVETFEENCCVMRYTTAGQLWNIIAPREFVDFSYTTSYEDGLLSCGVSLNYGEVRPNFVRGFNHPCGWFCVPLKDYPSHSLLTGYIQTELRGMLPQSAVDTAMASTLTNFYSDLKKALKS", "length": 207, "header": "tr|F1NKR7-1|F1NKR7_CHICK Isoform 1 of StAR related lipid transfer domain containing 4 OS=Gallus gallus OX=9031 GN=STARD4 PE=4 SV=1 CANONICAL=F1NKR7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U505-1", "url": "https://www.uniprot.org/uniprotkb/F1NKR7/entry#A0A3Q2U505-1", "sequence": { "sequence": "MAPRRHIARYEVTGRTPMDLLPDPAPLATRLQNTLLRYHSIADSEWRIARKTKDAVVWRKPSEEFSGYLYKAQGVVEDITNRIVDHIRPGPYRLDWDSLMTTMDIVETFEENCCVMRYTTAGQLWNIIAPREFVDFSYTTSYEDGLLSCGVSLNYGEVRPNFVRGFNHPCGWFCVPLKDYPSHSLLTGYIQTELRGMLPQSAVDTAMASTLTNFYSDLKKALKS", "length": 224, "header": "tr|A0A3Q2U505-1|F1NKR7_CHICK Computationally mapped isoform of StAR related lipid transfer domain containing 4 OS=Gallus gallus OX=9031 GN=STARD4 PE=4 SV=1 CANONICAL=F1NKR7-1" }, "locus": { "chromosome": "Z", "start_pos": 47188287, "end_pos": 47183681, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019610.1", "url": "https://www.ensembl.org/id/ENSGALT00010019610.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011158.1", "url": "https://www.ensembl.org/id/ENSGALP00010011158.1" } ] } }, { "isoform_ac": "F1NKR7-1", "url": "https://www.uniprot.org/uniprotkb/F1NKR7/entry#F1NKR7-1", "sequence": { "sequence": "MDLLPDPAPLATRLQNTLLRYHSIADSEWRIARKTKDAVVWRKPSEEFSGYLYKAQGVVEDITNRIVDHIRPGPYRLDWDSLMTTMDIVETFEENCCVMRYTTAGQLWNIIAPREFVDFSYTTSYEDGLLSCGVSLNYGEVRPNFVRGFNHPCGWFCVPLKDYPSHSLLTGYIQTELRGMLPQSAVDTAMASTLTNFYSDLKKALKS", "length": 207, "header": "tr|F1NKR7-1|F1NKR7_CHICK Isoform 1 of StAR related lipid transfer domain containing 4 OS=Gallus gallus OX=9031 GN=STARD4 PE=4 SV=1 CANONICAL=F1NKR7-1" }, "locus": { "chromosome": "Z", "start_pos": 47188287, "end_pos": 47184133, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019608.1", "url": "https://www.ensembl.org/id/ENSGALT00010019608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011156.1", "url": "https://www.ensembl.org/id/ENSGALP00010011156.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769322", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769322", "resource": "KEGG Pathway" }, { "id": "R-GGA-196108", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196108", "resource": "Reactome", "description": "Pregnenolone biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2Q8F3-1", "protein_name": "StAR related lipid transfer domain containing 4", "gene_name": "STARD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGLPDAAVLATRLKNTLLQYHSIEDDKWRVAKKMKDVTIWRKPSEEFNGHLFKAQGVIDDVVNNVIDHIRPGPCRLDWDSLMTSMDILEHFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGYEEGLLSCGISLDWSEKRSEFVRGYNHPCGWFCVPLKDNPNRSLLTGYIQTDLRGMIPQSAVDTAMASTLINFYGDLQKALQKT", "length": 208 }, "evidence": [ { "id": "F1NKR7", "url": "https://omabrowser.org/oma/group/F1NKR7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3Z9I9-1", "protein_name": "StAR-related lipid transfer protein 4", "gene_name": "Stard4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPGSGWSQSSRKLKMEGLSDVASISTKLQNTLIQYHSIEEDQWRVAKKVKDVTVWRKPSEEFNGYLYKAQGVMDDVVNNVIDHIRPGPWRLDWDRLMTSLDILEHFEENCCVMRYTTAGQLLNIISPREFVDFSYTVGYEEGLLSCGVSVEWSETRPEFVRGYNHPCGWFCVPLKDSPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLANFYSDLRKALRKA", "length": 224 }, "evidence": [ { "id": "F1NKR7", "url": "https://omabrowser.org/oma/group/F1NKR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96DR4-1", "protein_name": "StAR-related lipid transfer protein 4", "gene_name": "STARD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGLSDVASFATKLKNTLIQYHSIEEDKWRVAKKTKDVTVWRKPSEEFNGYLYKAQGVIDDLVYSIIDHIRPGPCRLDWDSLMTSLDILENFEENCCVMRYTTAGQLWNIISPREFVDFSYTVGYKEGLLSCGISLDWDEKRPEFVRGYNHPCGWFCVPLKDNPNQSLLTGYIQTDLRGMIPQSAVDTAMASTLTNFYGDLRKAL", "length": 205 }, "evidence": [ { "id": "F1NKR7", "url": "https://omabrowser.org/oma/group/F1NKR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of bile acid biosynthetic process", "id": "GO:0070859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070859", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" }, { "name": "intracellular cholesterol transport", "id": "GO:0032367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032367", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" }, { "name": "cholesterol import", "id": "GO:0070508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070508", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" }, { "name": "positive regulation of cholesterol metabolic process", "id": "GO:0090205", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090205", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" }, { "name": "cholesterol transport involved in cholesterol storage", "id": "GO:0010879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010879", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" }, { "name": "cholesterol transfer activity", "id": "GO:0120020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120020", "evidence": [ { "database": "UniProtKB", "id": "F1NKR7", "url": "https://www.uniprot.org/uniprotkb/F1NKR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C347-1", "uniprot_ac": "E1C347", "uniprot_id": "E1C347_CHICK", "mass": { "chemical_mass": 40103.0, "monoisotopic_mass": 40103.0 }, "refseq": { "ac": "NP_001264479", "name": "guanine nucleotide-binding protein G(o) subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264479" }, "gene_names": [ { "name": "GNAO1", "type": "recommended", "evidence": [ { "id": "E1C347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ] }, { "name": "GNAO1", "type": "synonym", "evidence": [ { "id": "NP_001264479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264479" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein G(o) subunit alpha", "type": "recommended", "evidence": [ { "id": "E1C347", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C347/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O", "type": "synonym", "evidence": [ { "id": "NP_001264479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264479" } ] }, { "name": "guanine nucleotide-binding protein G(o) subunit alpha", "type": "synonym", "evidence": [ { "id": "NP_001264479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264479" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888497.384343.1, SRR12888502.71675.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000247.1. On Apr 11, 2013 this sequence version replaced XP_414065.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264479", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264479" } ] }, { "annotation": "Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels.", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2UEZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UEZ9#function" }, { "database": "UniProtKB", "id": "ARBA00045229", "url": "https://www.uniprot.org/uniprotkb/ARBA00045229#function" }, { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNAO1", "url": "https://www.uniprot.org/uniprotkb/E1C347", "locus": { "chromosome": "11", "start_pos": 2344258, "end_pos": 2224984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021247", "url": "https://www.ensembl.org/id/ENSGALG00010021247" } ] } } ], "crossref": [ { "id": "E1C347", "url": "https://alphafold.ebi.ac.uk/entry/E1C347", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003163", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003163", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415698", "url": "https://www.ncbi.nlm.nih.gov/gene/415698", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415698", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415698", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GKKDYMP", "url": "https://omabrowser.org/oma/group/GKKDYMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P1I2", "url": "https://www.orthodb.org/?gene=A0A1D5P1I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UEZ9", "url": "https://www.orthodb.org/?gene=A0A3Q2UEZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIU4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPP8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C347", "url": "https://www.orthodb.org/?gene=E1C347", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218:SF361", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218:SF361", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218:SF363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218:SF363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00503", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00503", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264479", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5P1I2", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P1I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UEZ9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UEZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UEZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UEZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C347-1", "url": "https://www.uniprot.org/uniprotkb/E1C347-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPFSPELLSAMMRLWADSGIQECFNRSREYQLNDSAQYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFAEKIKKSPLTICFPEYAGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY", "length": 354, "header": "tr|E1C347-1|E1C347_CHICK Isoform 1 of Guanine nucleotide-binding protein G(o) subunit alpha OS=Gallus gallus OX=9031 GN=GNAO1 PE=1 SV=3 CANONICAL=E1C347-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P1I2-1", "url": "https://www.uniprot.org/uniprotkb/E1C347/entry#A0A1D5P1I2-1", "sequence": { "sequence": "MTCLQAADLPALPGKEGGMKAWIYVRIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPFSPELLSAMMRLWADSGIQECFNRSREYQLNDSAQYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSSFTEAVAYIQAQYESKNKSPNKEIYTHITCATDTNNIQFVFDAVTDVIIANNLRGCGLY", "length": 326, "header": "tr|A0A1D5P1I2-1|A0A1D5P1I2_CHICK Computationally mapped isoform of G protein subunit alpha o1 OS=Gallus gallus OX=9031 GN=GNAO1 PE=1 SV=2 CANONICAL=E1C347-1" }, "locus": { "chromosome": "11", "start_pos": 2335867, "end_pos": 2268863, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051510.1", "url": "https://www.ensembl.org/id/ENSGALT00010051510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030701.1", "url": "https://www.ensembl.org/id/ENSGALP00010030701.1" } ] } }, { "isoform_ac": "A0A3Q2UEZ9-1", "url": "https://www.uniprot.org/uniprotkb/E1C347/entry#A0A3Q2UEZ9-1", "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPFSPELLSAMMRLWADSGIQECFNRSREYQLNDSAQYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSSFTEAVAYIQAQYESKNKSPNKEIYTHITCATDTNNIQFVFDAVTDVIIANNLRGCGLY", "length": 354, "header": "tr|A0A3Q2UEZ9-1|E1C347_CHICK Computationally mapped isoform of Guanine nucleotide-binding protein G(o) subunit alpha OS=Gallus gallus OX=9031 GN=GNAO1 PE=1 SV=1 CANONICAL=E1C347-1" }, "locus": { "chromosome": "11", "start_pos": 2335867, "end_pos": 2225218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051516.1", "url": "https://www.ensembl.org/id/ENSGALT00010051516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030707.1", "url": "https://www.ensembl.org/id/ENSGALP00010030707.1" } ] } }, { "isoform_ac": "A0A8V0ZIU4-1", "url": "https://www.uniprot.org/uniprotkb/E1C347/entry#A0A8V0ZIU4-1", "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPFSPELLSAMMRLWADSGIQECFNRSREYQLNDSAQYTTQASAAVLGFIPLMALHSQSSTMKENLISYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSSFTEAVAYIQAQYESKNKSPNKEIYTHITCATDTNNIQFVFDAVTDVIIANNLRGCGLY", "length": 384, "header": "tr|A0A8V0ZIU4-1|A0A8V0ZIU4_CHICK Computationally mapped isoform of G protein subunit alpha o1 OS=Gallus gallus OX=9031 GN=GNAO1 PE=1 SV=1 CANONICAL=E1C347-1" }, "locus": { "chromosome": "11", "start_pos": 2335867, "end_pos": 2225218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051514.1", "url": "https://www.ensembl.org/id/ENSGALT00010051514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030705.1", "url": "https://www.ensembl.org/id/ENSGALP00010030705.1" } ] } }, { "isoform_ac": "A0A8V0ZPP8-1", "url": "https://www.uniprot.org/uniprotkb/E1C347/entry#A0A8V0ZPP8-1", "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPFSPELLSAMMRLWADSGIQECFNRSREYQLNDSAQYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTVSAKWVPQSPVLLYGMPWSQHHWEMAVCWLWDCSYLLLCVAAPLTSQGGLSSSALPKIKSCIPGNGSCAGEVTVFYFSLLADLCVFKVY", "length": 330, "header": "tr|A0A8V0ZPP8-1|A0A8V0ZPP8_CHICK Computationally mapped isoform of G protein subunit alpha o1 OS=Gallus gallus OX=9031 GN=GNAO1 PE=1 SV=1 CANONICAL=E1C347-1" }, "locus": { "chromosome": "11", "start_pos": 2327960, "end_pos": 2225218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051512.1", "url": "https://www.ensembl.org/id/ENSGALT00010051512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030703.1", "url": "https://www.ensembl.org/id/ENSGALP00010030703.1" } ] } }, { "isoform_ac": "E1C347-1", "url": "https://www.uniprot.org/uniprotkb/E1C347/entry#E1C347-1", "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPFSPELLSAMMRLWADSGIQECFNRSREYQLNDSAQYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFAEKIKKSPLTICFPEYAGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY", "length": 354, "header": "tr|E1C347-1|E1C347_CHICK Isoform 1 of Guanine nucleotide-binding protein G(o) subunit alpha OS=Gallus gallus OX=9031 GN=GNAO1 PE=1 SV=3 CANONICAL=E1C347-1" }, "locus": { "chromosome": "11", "start_pos": 2342723, "end_pos": 2225218, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051520.1", "url": "https://www.ensembl.org/id/ENSGALT00010051520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030711.1", "url": "https://www.ensembl.org/id/ENSGALP00010030711.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415698", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415698", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A9G3-1", "protein_name": "Guanine nucleotide-binding protein G(o) subunit alpha", "gene_name": "GNAO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSTFTEAVAYIQAQYESRNKSAHKEVYTHVTCATDTNNIQFVFDAVTDVIIAKNLRGCGLY", "length": 354 }, "evidence": [ { "id": "E1C347", "url": "https://omabrowser.org/oma/group/E1C347/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P09471-1", "protein_name": "Guanine nucleotide-binding protein G(o) subunit alpha", "gene_name": "GNAO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY", "length": 354 }, "evidence": [ { "id": "E1C347", "url": "https://omabrowser.org/oma/group/E1C347/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16378-1", "protein_name": "G protein alpha o subunit", "gene_name": "Galphao", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAYIQAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY", "length": 354 }, "evidence": [ { "id": "E1C347", "url": "https://omabrowser.org/oma/group/E1C347/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P18872-1", "protein_name": "Guanine nucleotide-binding protein G(o) subunit alpha", "gene_name": "Gnao1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGVEYGDKERKTDSKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAGDYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYPGSNTYEDAAAYIQTQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY", "length": 354 }, "evidence": [ { "id": "E1C347", "url": "https://omabrowser.org/oma/group/E1C347/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "G protein-coupled serotonin receptor binding", "id": "GO:0031821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031821", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "corticotropin-releasing hormone receptor 1 binding", "id": "GO:0051430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051430", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "mu-type opioid receptor binding", "id": "GO:0031852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031852", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" }, { "name": "G protein-coupled dopamine receptor signaling pathway", "id": "GO:0007212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007212", "evidence": [ { "database": "UniProtKB", "id": "E1C347", "url": "https://www.uniprot.org/uniprotkb/E1C347" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": 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"sequence": { "sequence": "MEEIYAKFVSQKISKTRWRPLSSGSLQTAETFATGSWDNEENYVSLWSIGDLGNVDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVSQQWTTAHYHAGPGSPSCSSAPCTGVVCNSPEIVTVGEDGRINLFRADYKEAIKTIVWEVHFHPSNPDHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQTNVHQSLISSWLSTDPARDRIEITSLLPSRTLSVNSLDVLGPCLVCGTDAEAIYVTRQLFS", "length": 284 }, "evidence": [ { "id": "E1C370", "url": "https://omabrowser.org/oma/group/E1C370/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P59235-1", "protein_name": "Nucleoporin Nup43", "gene_name": "Nup43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MEEIYAKFVSQKISKTRWRPLPPGSLQTAETFATGSWDNEENYISLWSIGDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWTTAHYHTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLLPSRSLSVNTLDVLGPCLVCGTDAEAIYVTRHLFS", "length": 380 }, "evidence": [ { "id": "E1C370", "url": "https://omabrowser.org/oma/group/E1C370/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VE85-1", "protein_name": "Nucleoporin 43kD", "gene_name": "Nup43", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIANVSTHYISEKVSQVRWLPEELQQSERFVTGSWDMDQNFVRLWRLQSNQYVTATDSEVDQIPRCMDKVRMEDDVTAMEFVDKDTLAVSCADGHLSVFNVHRAVEEDQMQRTSRSGRLHCFQRSQEPAPCTDLSVYGTDIATAGEDGCVSIVSVENVRQVKRQIEADSMALFSICYISQQELVTANRMGVIRMLDARVATEAQPKTTFMVASQDDKSNFVSSLAKHPMQQHILLCGSEEGSITVWDMRNLSYPASYLSAHKSPINEIGFHQKDPSKLFTAAEGGEVWMWSENKVLGCDYNKDGHSPWLSGDRVRSLVDVEGVLSNVRKSINSFDVHGSRLVCGGDTEAVYLVDNIV", "length": 358 }, "evidence": [ { "id": "E1C370", "url": "https://omabrowser.org/oma/group/E1C370/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C370", "url": "https://www.uniprot.org/uniprotkb/E1C370" } ], "pmid": "" }, { "name": "nuclear pore outer ring", "id": "GO:0031080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080", "evidence": [ { "database": "UniProtKB", "id": "E1C370", "url": "https://www.uniprot.org/uniprotkb/E1C370" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1C370", "url": "https://www.uniprot.org/uniprotkb/E1C370" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "E1C370", "url": "https://www.uniprot.org/uniprotkb/E1C370" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C370-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 374, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C370-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C370" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 342, "end_pos": 344 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"chemical_mass": 48288.0, "monoisotopic_mass": 48288.0 }, "refseq": {}, "gene_names": [ { "name": "BZW2", "type": "recommended", "evidence": [ { "id": "F1NM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM03" } ] } ], "protein_names": [ { "name": "eIF5-mimic protein 1", "type": "recommended", "evidence": [ { "id": "F1NM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#names_and_taxonomy" } ] }, { "name": "Basic leucine zipper and W2 domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "F1NM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NM03", "url": "https://www.uniprot.org/uniprotkb/F1NM03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BZW2", "url": "https://www.uniprot.org/uniprotkb/F1NM03", "locus": { "chromosome": "2", "start_pos": 28434774, "end_pos": 28382647, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005255", "url": "https://www.ensembl.org/id/ENSGALG00010005255" } ] } } ], "crossref": [ { "id": "F1NM03", "url": "https://alphafold.ebi.ac.uk/entry/F1NM03", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010809", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010809", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11560", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11560", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420594", "url": "https://www.ncbi.nlm.nih.gov/gene/420594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420594", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELIQCIW", "url": "https://omabrowser.org/oma/group/ELIQCIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XFV7", "url": "https://www.orthodb.org/?gene=A0A8V0XFV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMG1", "url": "https://www.orthodb.org/?gene=A0A8V0XMG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQ79", "url": "https://www.orthodb.org/?gene=A0A8V0XQ79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSI2", "url": "https://www.orthodb.org/?gene=A0A8V0XSI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSI6", "url": "https://www.orthodb.org/?gene=A0A8V0XSI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSJ1", "url": "https://www.orthodb.org/?gene=A0A8V0XSJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NM03", "url": "https://www.orthodb.org/?gene=F1NM03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14208:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14208:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XFV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XFV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NM03", "url": "https://www.uniprot.org/uniprotkb/F1NM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NM03-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 419, "header": "tr|F1NM03-1|F1NM03_CHICK Isoform 1 of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XFV7-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#A0A8V0XFV7-1", "sequence": { "sequence": "MYLKAHPLLCRNFMNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 432, "header": "tr|A0A8V0XFV7-1|A0A8V0XFV7_CHICK Computationally mapped isoform of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "locus": { "chromosome": "2", "start_pos": 28434344, "end_pos": 28395578, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012454.1", "url": "https://www.ensembl.org/id/ENSGALT00010012454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007018.1", "url": "https://www.ensembl.org/id/ENSGALP00010007018.1" } ] } }, { "isoform_ac": "A0A8V0XMG1-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#A0A8V0XMG1-1", "sequence": { "sequence": "MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEAFFQI", "length": 415, "header": "tr|A0A8V0XMG1-1|A0A8V0XMG1_CHICK Computationally mapped isoform of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "locus": { "chromosome": "2", "start_pos": 28432738, "end_pos": 28403363, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012446.1", "url": "https://www.ensembl.org/id/ENSGALT00010012446.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007010.1", "url": "https://www.ensembl.org/id/ENSGALP00010007010.1" } ] } }, { "isoform_ac": "A0A8V0XQ79-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#A0A8V0XQ79-1", "sequence": { "sequence": "MRNFMNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 423, "header": "tr|A0A8V0XQ79-1|F1NM03_CHICK Computationally mapped isoform of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "locus": { "chromosome": "2", "start_pos": 28434344, "end_pos": 28402291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012452.1", "url": "https://www.ensembl.org/id/ENSGALT00010012452.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007016.1", "url": "https://www.ensembl.org/id/ENSGALP00010007016.1" } ] } }, { "isoform_ac": "A0A8V0XSI2-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#A0A8V0XSI2-1", "sequence": { "sequence": "MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKGKSISAAIYFAWTLDLVLT", "length": 388, "header": "tr|A0A8V0XSI2-1|F1NM03_CHICK Computationally mapped isoform of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "locus": { "chromosome": "2", "start_pos": 28427776, "end_pos": 28403363, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012445.1", "url": "https://www.ensembl.org/id/ENSGALT00010012445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007009.1", "url": "https://www.ensembl.org/id/ENSGALP00010007009.1" } ] } }, { "isoform_ac": "A0A8V0XSI6-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#A0A8V0XSI6-1", "sequence": { "sequence": "MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYLPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 410, "header": "tr|A0A8V0XSI6-1|F1NM03_CHICK Computationally mapped isoform of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "locus": { "chromosome": "2", "start_pos": 28434344, "end_pos": 28403363, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012450.1", "url": "https://www.ensembl.org/id/ENSGALT00010012450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007014.1", "url": "https://www.ensembl.org/id/ENSGALP00010007014.1" } ] } }, { "isoform_ac": "A0A8V0XSJ1-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#A0A8V0XSJ1-1", "sequence": { "sequence": "MEQTVSLFCSLYNSRTAGSPLPFVLSFGFPRSSLCPVPPASSRQWHGRAEGAAAAAPCVNVSVLHSSIVCRCQCRRRACPPGARTHPTDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 488, "header": "tr|A0A8V0XSJ1-1|F1NM03_CHICK Computationally mapped isoform of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "locus": { "chromosome": "2", "start_pos": 28434344, "end_pos": 28382735, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012455.1", "url": "https://www.ensembl.org/id/ENSGALT00010012455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007019.1", "url": "https://www.ensembl.org/id/ENSGALP00010007019.1" } ] } }, { "isoform_ac": "F1NM03-1", "url": "https://www.uniprot.org/uniprotkb/F1NM03/entry#F1NM03-1", "sequence": { "sequence": "MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 419, "header": "tr|F1NM03-1|F1NM03_CHICK Isoform 1 of eIF5-mimic protein 1 OS=Gallus gallus OX=9031 GN=BZW2 PE=3 SV=1 CANONICAL=F1NM03-1" }, "locus": { "chromosome": "2", "start_pos": 28434344, "end_pos": 28403363, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012449.1", "url": "https://www.ensembl.org/id/ENSGALT00010012449.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007013.1", "url": "https://www.ensembl.org/id/ENSGALP00010007013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420594", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BQI6-1", "protein_name": "eIF5-mimic protein 1", "gene_name": "BZW2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 419 }, "evidence": [ { "id": "F1NM03", "url": "https://omabrowser.org/oma/group/F1NM03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7HHZ8-1", "protein_name": "eIF5-mimic protein 1", "gene_name": "Bzw2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAIAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPAAILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELVLLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHAAKGKSVFLDQMKKFVEWLQNAEEESESEGEEN", "length": 419 }, "evidence": [ { "id": "F1NM03", "url": "https://omabrowser.org/oma/group/F1NM03/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LUC1-1", "protein_name": "eIF5-mimic protein 1", "gene_name": "bzw2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTGKQQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGGDLDALAKFLDVTGSRLDYRRYADTLFDILIAGSMLAPGGTRIDDADKTKVTQHCVFNAEENHTTIRSYAQVFNKLIRRYKYLEKAFEEEIKKLLLFLKGFTESEQTKLAMLTGVLLANGTLPPPILTSLFSDNLVKEGISASFAVKMFKAWIAEKDANAVTSALRKANLDKKLLELFPANKQNVEHFTKFFTEAGLKELSDFLRTQQTLGTRKELQKELQERLSQQCPIREIVVYVKEEMKKNDLQEQAVIGLLWTCLMNAVEWNKKEELVTEQALKHLKHYAPLLAVFSTQGQSELVLLLKIQEYCYDNIHFMKSFSKIVVLFYKADVVSEEAIMKWYKDAHAAKGKSVFLEQMKKFVEWLQNAEEESESEGEED", "length": 421 }, "evidence": [ { "id": "F1NM03", "url": "https://omabrowser.org/oma/group/F1NM03/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91VK1-1", "protein_name": "eIF5-mimic protein 1", "gene_name": "Bzw2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSEAEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELVLLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHAAKGKSVFLDQMKKFVEWLQNAEEESESEGEES", "length": 419 }, "evidence": [ { "id": "F1NM03", "url": "https://omabrowser.org/oma/group/F1NM03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VNE2-1", "protein_name": "Protein krasavietz", "gene_name": "kra", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQKTERPVLSGQRIKTRKRDEREKYDPTGFRDAVIAGLEKTEGDLEQISKYLDSAGNKLDYRRYGEVLFDILIAGGLLVPGGSISQDGEKPRTSYCIFDAPESMESMRNHEQVFVKLIRRYKYLEKMFEEEMGKVLLFVKGFTPSERIKLARMTALWLVNGSVPPNVLLVLNNEHLIKDGIALEFLLELFQTFKQEKGIAYLIQALKKGGLESKLMDFFPPNKRTEEYFKQVFLDKELNEIVKLHKAQASQEAKRELQQALIDDINDEKPYNEITSDIKDFSQRTNIPDHEIIVIIWSTIMSLGEWNKKEELVTDQAVRHLKNYCPLLQAFASTDRSELALILKVQEFCYENMNFMKAFQKIILLFYKTEVLSEEIILRWYKEGHSNKGKMHFLEQMRKFVEWLQSAEEESESEDEQKNGE", "length": 422 }, "evidence": [ { "id": "F1NM03", "url": "https://omabrowser.org/oma/group/F1NM03/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTT7-1", "protein_name": "eIF5-mimic protein 1", "gene_name": "Bzw2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNKHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDEMKKLLLFLKAFSEAEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAEKDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSSQGQSELVLLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHAAKGKSVFLDQMKKFVEWLQNAEEESESEGEES", "length": 419 }, "evidence": [ { "id": "F1NM03", "url": "https://omabrowser.org/oma/group/F1NM03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NM03", "url": "https://www.uniprot.org/uniprotkb/F1NM03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "F1NM03", "url": "https://www.uniprot.org/uniprotkb/F1NM03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NM03" }, { "id": "PS51363", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51363" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "W2", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 415, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3Q8-1", "uniprot_ac": "E1C3Q8", "uniprot_id": "E1C3Q8_CHICK", "mass": { "chemical_mass": 44239.0, "monoisotopic_mass": 44239.0 }, "refseq": { "ac": "XP_004938283", "name": "golgin-45", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938283" }, "gene_names": [ { "name": "BLZF1", "type": "recommended", "evidence": [ { "id": "E1C3Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8" } ] }, { "name": "BLZF1", "type": "synonym", "evidence": [ { "id": "XP_004938283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938283" } ] } ], "protein_names": [ { "name": "Basic leucine zipper nuclear factor 1", "type": "synonym", "evidence": [ { "id": "E1C3Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8/entry#names_and_taxonomy" } ] }, { "name": "golgin-45", "type": "synonym", "evidence": [ { "id": "XP_004938283", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938283" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938283" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3Q8", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BLZF1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8", "locus": { "chromosome": "1", "start_pos": 83932898, "end_pos": 83942112, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005293", "url": "https://www.ensembl.org/id/ENSGALG00010005293" } ] } } ], "crossref": [ { "id": "E1C3Q8", "url": "https://alphafold.ebi.ac.uk/entry/E1C3Q8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015225", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015225", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418371", "url": "https://www.ncbi.nlm.nih.gov/gene/418371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418371", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIDTHKL", "url": "https://omabrowser.org/oma/group/MIDTHKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQG4", "url": "https://www.orthodb.org/?gene=A0A8V0XQG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3Q8", "url": "https://www.orthodb.org/?gene=E1C3Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13066", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13066", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13066:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13066:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-162658", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162658", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938283", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938283", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XQG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Q8", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3Q8-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSLEKVDYASSPIRGPGDGMETEQMGESLEVSAGASATNHQVRHSPQKKAVSSLSPGVLQLGQIHADKSVEVEAVRILVPKAAITHVVATKNAKVAKSAGHKGDAFHQSDGTADPKKEQTELKNAIEKLKNSEKRLLQDKEGLSNQLRIQTEVNRELKKLLVASVGDDLQYHFERMAREKNQLILENEVLGRNLSQLSEQLERMSIQCDVWRSKFLASRVMADELTNTRAILQRQTRDAQTAIQDLLNERDQFRQEMIHTQKLLEELMVSLQWGRQQTYYPSAQPYTTTELASVNCKLAKAVSSHLLGNVGTSSPKKTSTAVEFCNTPAEKMAERVLRVLDPAARTETSTEASFSETSPSSFLSTKKNIGRFHPYTRYEDITFNCCDHCQGELIAL", "length": 397, "header": "tr|E1C3Q8-1|E1C3Q8_CHICK Isoform 1 of Basic leucine zipper nuclear factor 1 OS=Gallus gallus OX=9031 GN=BLZF1 PE=4 SV=3 CANONICAL=E1C3Q8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XQG4-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8/entry#A0A8V0XQG4-1", "sequence": { "sequence": "MTSLEKVDYASSPIRGPGDGMETEQMGESLEVSAGASATNHQVRHSPQKKAVSSLSPGVLQLGQIHADKSVEVEAVRILVPKAAITHVVATKNAKVAKSAGHKGDAFHQSDGTADPKKEQTELKNAIEKLKNSEKRLLQDKEGLSNQLRIQTEVNRELKKLLVASVGDDLQYHFERMAREKNQLILENEVLGRNLSQLSEQLERMSIQCDVWRSKFLASRVMADELTNTRAILQRQTRDAQTAIQDLLNERDQFRQEMIHTQKTFSFLCRLLEELMVSLQWGRQQTYYPSAQPYTTTELASVNCKLAKAVSSHLLGNVGTSSPKKTSTAVEFCNTPAEKMAERVRTLHITQSFNTAQGQGHAF", "length": 363, "header": "tr|A0A8V0XQG4-1|E1C3Q8_CHICK Computationally mapped isoform of Basic leucine zipper nuclear factor 1 OS=Gallus gallus OX=9031 GN=BLZF1 PE=4 SV=1 CANONICAL=E1C3Q8-1" }, "locus": { "chromosome": "1", "start_pos": 83941588, "end_pos": 83937081, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012553.1", "url": "https://www.ensembl.org/id/ENSGALT00010012553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007117.1", "url": "https://www.ensembl.org/id/ENSGALP00010007117.1" } ] } }, { "isoform_ac": "E1C3Q8-1", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8/entry#E1C3Q8-1", "sequence": { "sequence": "MTSLEKVDYASSPIRGPGDGMETEQMGESLEVSAGASATNHQVRHSPQKKAVSSLSPGVLQLGQIHADKSVEVEAVRILVPKAAITHVVATKNAKVAKSAGHKGDAFHQSDGTADPKKEQTELKNAIEKLKNSEKRLLQDKEGLSNQLRIQTEVNRELKKLLVASVGDDLQYHFERMAREKNQLILENEVLGRNLSQLSEQLERMSIQCDVWRSKFLASRVMADELTNTRAILQRQTRDAQTAIQDLLNERDQFRQEMIHTQKLLEELMVSLQWGRQQTYYPSAQPYTTTELASVNCKLAKAVSSHLLGNVGTSSPKKTSTAVEFCNTPAEKMAERVLRVLDPAARTETSTEASFSETSPSSFLSTKKNIGRFHPYTRYEDITFNCCDHCQGELIAL", "length": 397, "header": "tr|E1C3Q8-1|E1C3Q8_CHICK Isoform 1 of Basic leucine zipper nuclear factor 1 OS=Gallus gallus OX=9031 GN=BLZF1 PE=4 SV=3 CANONICAL=E1C3Q8-1" }, "locus": { "chromosome": "1", "start_pos": 83941588, "end_pos": 83936635, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012557.1", "url": "https://www.ensembl.org/id/ENSGALT00010012557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007121.1", "url": "https://www.ensembl.org/id/ENSGALP00010007121.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418371", "resource": "KEGG Pathway" }, { "id": "R-GGA-162658", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-162658", "resource": "Reactome", "description": "Golgi Cisternae Pericentriolar Stack Reorganization" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JM41-1", "protein_name": "Golgin-45", "gene_name": "blzf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSAELIIKDVSVVAVRGPGDGMETDKPLPAPEQLTEAPLQKICSPKHSPRVATGSPGVLHLGKVSRDACLELEAVRIVVPRAAIIRTGRSGAHTDDRGSPQHGDEPPPAPPSPPPPAEPLQEYKNSLEKLQSSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNHLILENETLCRNLSHTAEQLERMSIQCDVWRSKFLASRVMAEELTNARSALQRQTRDAQCAIQDLLSEREEFSRDMTHTHRCLEQLLVSLQWGRQQTYYPSAKPLSTGELATANHKLADAINAHLLGKLENSGGKKSPSTEICNTPAEKMAEKVLRSLDPVCVSEQEHDASSSDSPFLPNRKSIGRFHPYTRYENITFNCCERCHGEIIVL", "length": 394 }, "evidence": [ { "id": "E1C3Q8", "url": "https://omabrowser.org/oma/group/E1C3Q8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N7E1-1", "protein_name": "Basic leucine zipper nuclear factor 1", "gene_name": "BLZF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTTLESLETKAILTPSPIRGAGDGMETEEPPKSIEVTPGIQPITHHILQSPRKKSVPSESPGVLQLGKILAEKAVEVEAVRILVPKAAITHNIPYKNAKVKSLGHHKGELLGQPEGVREPRKELSEVKNTLEKLKNSERRLLQDKEGLSNQLRVQSEVNRELKKLLVASVGDDLQYHFERVAREKNQLILENEALGRNIAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAVLQRQNRDAQSAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYYPSGQPHSTAELALTNHKLAKAVNSHLLGNVGTNGQKKVPSTVEFCSTPAEKMAETVLRILDPVTCTESSPDNPFSESSPTTLLATKKNIGRFHPYTRYENITFNCCNHCQGELIAL", "length": 401 }, "evidence": [ { "id": "E1C3Q8", "url": "https://omabrowser.org/oma/group/E1C3Q8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LIF5-1", "protein_name": "Basic leucine zipper nuclear factor 1", "gene_name": "BLZF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTTLEGLETKALLTSAPIRGAGDGMETEEPPKTVEVTSGIQPIKHHILQSPRKKAVPSESPGVLQLGKIIAEKAVEVEAIRILVPKAAISHDIPNKNAKAKSLGHHKGEILGQPEGIVEPRKEVSEVKTVLEKLKNSERRLLQDKEGLSNQLRVQSEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNVAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAVLQRQNRDAQSAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYYPSAQPHSTAELALTNHKLAKAVNSHLLGNVGTNGQKRIPSTIEFCSTPAEKMAETVLRILDPITCTENSPGNPFSESSPTTLLATKKNIGRFHPYTRYENVTFNCCNHCQGELIAL", "length": 401 }, "evidence": [ { "id": "E1C3Q8", "url": "https://omabrowser.org/oma/group/E1C3Q8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6AYB8-1", "protein_name": "Golgin-45", "gene_name": "Blzf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKMTTLKSFESKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKKVPSDSPGVLQLGKILNEKTVEVEAVRIFVPKAAITHDIPTKSAKVKSLGHHREELHNQSEVVTDPRKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQHQNRDAQSAIQDLLSEREQFRQEMISTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHRLAEAVHAHLLGNVGISHPKRTPATAEVCSTPAEKMAEKVLRILDPVACTESSPDNAFAESTLLTTKKNIGRFHPYTRYENITFNCCSHCQGELLAL", "length": 400 }, "evidence": [ { "id": "E1C3Q8", "url": "https://omabrowser.org/oma/group/E1C3Q8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2X8-1", "protein_name": "Golgin-45", "gene_name": "Blzf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKMTTLKSSENKGILTSTPIRGAGDGMETEEPPKSVEVTHGVQPINQHVLPSPRKKVSSDSPGVLQLGKILNERTVEVEAVRIFVPKAAITHDIPTKNTKVKSLGHHREELHNQAEVVTDPRKELSEVKKVLEKLKNSERRLLQDKEGLSNQLRVQTEINRELKKLLVASVGDDPQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNFRVVLQRQNRDAQSAIQDLLSEREQFRQEMTSTQKFLEELLVSLQWGREQTYSPNTQPHSTADLALTNHGLAQAIHAHLLGNVGISHQKKIPTTVEFCSTPAEKMAEKVLRILDPVACTESSPDNQFAESSPTTLLTTKKNIGRFHPYTRYENITFNCCNHCQGELIAL", "length": 403 }, "evidence": [ { "id": "E1C3Q8", "url": "https://omabrowser.org/oma/group/E1C3Q8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2G9-1", "protein_name": "Golgin-45", "gene_name": "BLZF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTKNLETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKAVPSESPGVLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNHKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDPVTCKESSPDNPFFESSPTTLLATKKNIGRFHPYTRYENITFNCCNHCRGELIAL", "length": 400 }, "evidence": [ { "id": "E1C3Q8", "url": "https://omabrowser.org/oma/group/E1C3Q8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q8", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q8", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q8", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q8", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "E1C3Q8", "url": "https://www.uniprot.org/uniprotkb/E1C3Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C3Q8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 397, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C3Q8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C3Q8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1N9C5-1", "uniprot_ac": "F1N9C5", "uniprot_id": "F1N9C5_CHICK", "mass": { "chemical_mass": 62991.0, "monoisotopic_mass": 62991.0 }, "refseq": { "ac": "XP_414977", "name": "transmembrane protein 209", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414977" }, "gene_names": [ { "name": "TMEM209", "type": "recommended", "evidence": [ { "id": "F1N9C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9C5" } ] }, { "name": "TMEM209", "type": "synonym", "evidence": [ { "id": "XP_414977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414977" } ] } ], "protein_names": [ { "name": "Transmembrane protein 209", "type": "synonym", "evidence": [ { "id": "F1N9C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9C5/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 209", "type": "synonym", "evidence": [ { "id": "XP_414977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414977" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_414977.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414977" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1N9C5", "url": "https://www.uniprot.org/uniprotkb/F1N9C5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM209", "url": "https://www.uniprot.org/uniprotkb/F1N9C5", "locus": { "chromosome": "1", "start_pos": 1471509, "end_pos": 1483335, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006548", "url": "https://www.ensembl.org/id/ENSGALG00010006548" } ] } } ], "crossref": [ { "id": "F1N9C5", "url": "https://alphafold.ebi.ac.uk/entry/F1N9C5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008036", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008036", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416681", "url": "https://www.ncbi.nlm.nih.gov/gene/416681", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416681", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416681", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IRGMHLG", "url": "https://omabrowser.org/oma/group/IRGMHLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XQW1", "url": "https://www.orthodb.org/?gene=A0A8V0XQW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSX8", "url": "https://www.orthodb.org/?gene=A0A8V0XSX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N9C5", "url": "https://www.orthodb.org/?gene=F1N9C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21780:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21780:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414977", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XQW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N9C5", "url": "https://www.uniprot.org/uniprotkb/F1N9C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N9C5-1", "url": "https://www.uniprot.org/uniprotkb/F1N9C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPEQSPATSLIDRTIKMRKETEARKVVLAWGLLNVSFAGMIYTEMTGKLISTYYNITYWPLWYIELAFASLFSLNALFDFWRYFKYTVAPTSLVMSPGQQTLLGLQNTAVQTTPPRELTAKKVPSSTPSPPIQGQSVLSYSPSRSPSASPKFATSCIPGYSPQLQALSNNSASYSSTIAYSPGSTYNKISNFSPSPGGSPYPTSIGPMESGGLRSRYRSSPILYNSPTGKEDYMTDLKSLDTFLRSEEEKQHRVQLGSSDSSSPSSSPTFWNYSRSMGDYAQILRKFQYQLACRSQAPSAHKDEADLSSKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQLRRMGCPELQIGEASISSLKQAALVKAPLIPTLNAIVQYLDLTPNQEYLVERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSSIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFIQTPDKPDTSNENVFCIYQSSINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNVLWIFGE", "length": 560, "header": "tr|F1N9C5-1|F1N9C5_CHICK Isoform 1 of Transmembrane protein 209 OS=Gallus gallus OX=9031 GN=TMEM209 PE=1 SV=2 CANONICAL=F1N9C5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XQW1-1", "url": "https://www.uniprot.org/uniprotkb/F1N9C5/entry#A0A8V0XQW1-1", "sequence": { "sequence": "MTPEQSPATSLIDRTIKMRKETEARKVVLAWGLLNVSFAGMIYTEMTGKLISTYYNITYWPLWYIELAFASLFSLNALFDFWRYFKYTVAPTSLVMSPGQQTLLGLQNTAVQTTPPRELTAKKVPSSTPSPPIQGQSVLSYSPSRSPSASPKFATSCIPGYSPQLQALSNNSASYSSTIAYSPGSTYNKISNFSPSPGGSPYPTSIGPMESGGLRSRYRSSPILYNSPTGKEDYMTDLKSLDTFLRSEEEKQHRVQLGSSDSSSPSSSPTFWNYSRSMGDYAQILRKFQYQLACRSQAPSAHKDEADLSSKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQLRRMGCPELQIGEASISSLKQAALVKAPLIPTLNAIVQYLDLTPNQEYLVERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSSIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFIQTPDKPDTSNENVFCIYQSSINPPHYELIYQRHVYNLPKVHQCCCCHKIITRSYLSDLGCWLSAESKPQLNH", "length": 551, "header": "tr|A0A8V0XQW1-1|F1N9C5_CHICK Computationally mapped isoform of Transmembrane protein 209 OS=Gallus gallus OX=9031 GN=TMEM209 PE=1 SV=1 CANONICAL=F1N9C5-1" }, "locus": { "chromosome": "1", "start_pos": 1481763, "end_pos": 1473719, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015581.1", "url": "https://www.ensembl.org/id/ENSGALT00010015581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009073.1", "url": "https://www.ensembl.org/id/ENSGALP00010009073.1" } ] } }, { "isoform_ac": "A0A8V0XSX8-1", "url": "https://www.uniprot.org/uniprotkb/F1N9C5/entry#A0A8V0XSX8-1", "sequence": { "sequence": "MTPEQSPATSLIDRTIKMRKETEARKVVLAWGLLNVSFAGMIYTEMTGKLISTYYNITYWPLWYIELAFASLFSLNALFDFWRYFKYTVAPTSLVMSPGQQTLLGLQNTAVQTTPPRELTAKKVPSSTPSPPIQGQSVLSYSPSRSPSASPKFATSCIPGYSPQLQALSNNSASYSSTIAYSPGSTYNKISNFSPSPGGSPYPTSIGPMESGGLRSRYRSSPILYNSPTGKEDYMTDLKSLDTFLRSEEEKQHRVQLGSSDSSSPSSSPTFWNYSRSMGDYAQILRKFQYQLACRSQAPSAHKDEADLSSKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQLRRMGCPELQIGEASISSLKQAALVKAPLIPTLNAIVQYLDLTPNQEYLVERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSSIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFIQTPDKPGTVVHSILPELLFVSQQRLQNPYYLFNLSPTDTSNENVFCIYQSSINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNVLWIFGE", "length": 591, "header": "tr|A0A8V0XSX8-1|F1N9C5_CHICK Computationally mapped isoform of Transmembrane protein 209 OS=Gallus gallus OX=9031 GN=TMEM209 PE=1 SV=1 CANONICAL=F1N9C5-1" }, "locus": { "chromosome": "1", "start_pos": 1481763, "end_pos": 1472751, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015585.1", "url": "https://www.ensembl.org/id/ENSGALT00010015585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009076.1", "url": "https://www.ensembl.org/id/ENSGALP00010009076.1" } ] } }, { "isoform_ac": "F1N9C5-1", "url": "https://www.uniprot.org/uniprotkb/F1N9C5/entry#F1N9C5-1", "sequence": { "sequence": "MTPEQSPATSLIDRTIKMRKETEARKVVLAWGLLNVSFAGMIYTEMTGKLISTYYNITYWPLWYIELAFASLFSLNALFDFWRYFKYTVAPTSLVMSPGQQTLLGLQNTAVQTTPPRELTAKKVPSSTPSPPIQGQSVLSYSPSRSPSASPKFATSCIPGYSPQLQALSNNSASYSSTIAYSPGSTYNKISNFSPSPGGSPYPTSIGPMESGGLRSRYRSSPILYNSPTGKEDYMTDLKSLDTFLRSEEEKQHRVQLGSSDSSSPSSSPTFWNYSRSMGDYAQILRKFQYQLACRSQAPSAHKDEADLSSKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQLRRMGCPELQIGEASISSLKQAALVKAPLIPTLNAIVQYLDLTPNQEYLVERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSSIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFIQTPDKPDTSNENVFCIYQSSINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNVLWIFGE", "length": 560, "header": "tr|F1N9C5-1|F1N9C5_CHICK Isoform 1 of Transmembrane protein 209 OS=Gallus gallus OX=9031 GN=TMEM209 PE=1 SV=2 CANONICAL=F1N9C5-1" }, "locus": { "chromosome": "1", "start_pos": 1481763, "end_pos": 1472751, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015590.1", "url": "https://www.ensembl.org/id/ENSGALT00010015590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009079.1", "url": "https://www.ensembl.org/id/ENSGALP00010009079.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 128, "start_aa": "Thr", "end_pos": 128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr128", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416681", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416681", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VZE5-1", "protein_name": "Transmembrane protein 209", "gene_name": "TMEM209", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGEPNPSASLIDRTIKMRKETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQTLLGLKTAVVQTTPPRDLAATQIPSSPPPSIQGQSVLSYSPSRSPSTSPKFTTSCITGYSPQLQGLSSGGSGSYSPGVTFSPVSGYNKLASYSPSPSSSYPTTVGPVESSGLRSRYRSSPTIYNSPTDKEDYMTDLRTLDTFLRNEEEKQHRVKLGSPDSTSPSTSPTFWNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGCPELQIGEASITSLKQAALVKAPLIPTLNTIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCVYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE", "length": 559 }, "evidence": [ { "id": "F1N9C5", "url": "https://omabrowser.org/oma/group/F1N9C5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BBC2-1", "protein_name": "Transmembrane protein 209", "gene_name": "TMEM209", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWPDHPLPVVEGRKEAIGVAKMQGEPNPSASLIDRTIKMRRETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKCTVAATSLVVSPEQQTLLGLKTAVVQTTPPRDLAAAQIPPSPPSPSIQGQSVLSYSPSRSPSTSPKFTTSCITGYSPQLQGLSSGGSGSYSPGVTYSPISGYNKLASYSPSPPPPYPTTVGPVESSGLRSRYRSSPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQQRVKLGSPDSTSPPTSPTFWNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGCPELQIGEASITSLKQAALVKAPLIPTLNTIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE", "length": 581 }, "evidence": [ { "id": "F1N9C5", "url": "https://omabrowser.org/oma/group/F1N9C5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F6P528-1", "protein_name": "Transmembrane protein 209", "gene_name": "tmem209", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTPSKEGMTSLIERTIKLRKEEQARQVVLAWAVLNMSLAGMIYTEMSGKLLSRYYNITYWPIWYIELALASLFSLNALFDFWKYFKYTMAPSTIVVSPDQHRLLGLRGSGIQASPPQKQEKKEAPVSVQSSPLQGQNVLSFSPARPSSTSPKFSPSCVSGFSPPLSSTSSGGPFSPSMSFGKVLNYSPSQSSPPYPSSLGPAENTSLRSRYRTSPSVFNSPGGKEDCIDDLKTLEKFLRSEEEKSHRSQLGSPESTSPRHSPSFWNYNRTVGDYAQSLRKFQYQPACRSQAPSAHKDDTELGSKQAAEEVWARITTSRLVTDSIDSWTAKLRNWINDTILVHLVKEMDSINSQLRRMGCPELQIGEASISSLKQAAVVKASAIPTLNAIVQYLDVTPNQEYLVERIKELAHSGCMSSFRWNGGGDLKNRKWDTDLPTDSAILMHVLCTYLDSRLPPHPKYPDGKTFTSQHFMQTPNKPDVSNENLFCIHQSSTNPPHYQLVYQGHVYSLPKGRNNLFHTILMFLYIIKTKESGMLGRVNLGLSGVNVLWIFGD", "length": 553 }, "evidence": [ { "id": "F1N9C5", "url": "https://omabrowser.org/oma/group/F1N9C5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q68FR5-1", "protein_name": "Transmembrane protein 209", "gene_name": "Tmem209", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMQGEVSPSPSLIDRTIRMRKETESRKVVLAWGLLNVSMAGMIYTEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQTLLGLKPAVVQTTPPRDLAATQISPSPPSPSIQGQSVLSYSPSRSPSTSPKFATSCMTGYSPQLQGLSSGGLGSYSPAVTYSPVSGYSKLASFSLSPSSPYPTTVGPVESSGLRARYRSPPTAYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSTSPTFWNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEADLISKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWISETILVPLVQEIESVSTQMRRMGCPELQIGEASVTSLKQAALVKAPLIPTLNAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRRWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCVYQSAINPPHYELIYQRHVYSLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE", "length": 561 }, "evidence": [ { "id": "F1N9C5", "url": "https://omabrowser.org/oma/group/F1N9C5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BRG8-1", "protein_name": "Transmembrane protein 209", "gene_name": "Tmem209", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMQGDVSPNPSLIDRTIKMRKETETRKVVLAWGLLNVSMAGMIYTEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQALLGLKQAVVQTTPPRDLAATQISPSPPSPSIQGQSVLSYSPSRSPSTSPKFATSCMTGYSPQLQGLSSGGLGSYSPGVTYSPVSGYNKLASFSLSPSSPYPTTVGPVESSGLRARYRSPPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSTSPTFWNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEADLISKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWISETILVPLVQEIESVSTQMRRMGCPELQIGEASVTSLKQAALVRAPLIPTLNAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAVNPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE", "length": 561 }, "evidence": [ { "id": "F1N9C5", "url": "https://omabrowser.org/oma/group/F1N9C5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96SK2-1", "protein_name": "Transmembrane protein 209", "gene_name": "TMEM209", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQGEAHPSASLIDRTIKMRKETEARKVVLAWGLLNVSMAGMIYTEMTGKLISSYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQTLLGLKTAVVQTTPPHDLAATQIPPAPPSPSIQGQSVLSYSPSRSPSTSPKFTTSCMTGYSPQLQGLSSGGSGSYSPGVTYSPVSGYNKLASFSPSPPSPYPTTVGPVESSGLRSRYRSSPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSSSPTFWNYSRSMGDYAQTLKKFQYQLACRSQAPCANKDEADLSSKQAAEEVWARVAMNRQLLDHMDSWTAKFRNWINETILVPLVQEIESVSTQMRRMGCPELQIGEASITSLKQAALVKAPLIPTLNTIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAINPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE", "length": 561 }, "evidence": [ { "id": "F1N9C5", "url": "https://omabrowser.org/oma/group/F1N9C5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1N9C5", "url": "https://www.uniprot.org/uniprotkb/F1N9C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 128 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NTD5-1", "uniprot_ac": "F1NTD5", "uniprot_id": "F1NTD5_CHICK", "mass": { "chemical_mass": 37763.0, "monoisotopic_mass": 37763.0 }, "refseq": { "ac": "XP_001234274", "name": "single-stranded DNA-binding protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234274" }, "gene_names": [ { "name": "SSBP2", "type": "recommended", "evidence": [ { "id": "F1NTD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD5" } ] }, { "name": "SSBP2", "type": "synonym", "evidence": [ { "id": "XP_001234274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234274" } ] } ], "protein_names": [ { "name": "Single stranded DNA binding protein 2", "type": "synonym", "evidence": [ { "id": "F1NTD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD5/entry#names_and_taxonomy" } ] }, { "name": "single-stranded DNA-binding protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_001234274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234274" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001234274.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234274" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NTD5", "url": "https://www.uniprot.org/uniprotkb/F1NTD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SSBP2", "url": "https://www.uniprot.org/uniprotkb/F1NTD5", "locus": { "chromosome": "Z", "start_pos": 64411481, "end_pos": 64244514, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006575", "url": "https://www.ensembl.org/id/ENSGALG00010006575" } ] } } ], "crossref": [ { "id": "F1NTD5", "url": "https://alphafold.ebi.ac.uk/entry/F1NTD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000023089", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000023089", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "770958", "url": "https://www.ncbi.nlm.nih.gov/gene/770958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770958", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770958", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XQZ2", "url": "https://www.orthodb.org/?gene=A0A8V0XQZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XT03", "url": "https://www.orthodb.org/?gene=A0A8V0XT03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NTD5", "url": "https://www.orthodb.org/?gene=F1NTD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12610", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12610", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12610:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12610:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04503", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04503", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001234274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XQZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XT03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XT03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTD5", "url": "https://www.uniprot.org/uniprotkb/F1NTD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NTD5-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYGKGKSNSSVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMSGLGGMDSHHMNGSLGSGDMDSISKNSPSNMSMSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 360, "header": "tr|F1NTD5-1|F1NTD5_CHICK Isoform 1 of Single stranded DNA binding protein 2 OS=Gallus gallus OX=9031 GN=SSBP2 PE=4 SV=2 CANONICAL=F1NTD5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XQZ2-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD5/entry#A0A8V0XQZ2-1", "sequence": { "sequence": "MYGKGKSNSSVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMSGLGGMDSHHMNGSLGSGDMDSISKNSPSNMSMSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 330, "header": "tr|A0A8V0XQZ2-1|F1NTD5_CHICK Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Gallus gallus OX=9031 GN=SSBP2 PE=4 SV=1 CANONICAL=F1NTD5-1" }, "locus": { "chromosome": "Z", "start_pos": 64409472, "end_pos": 64244541, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015667.1", "url": "https://www.ensembl.org/id/ENSGALT00010015667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009104.1", "url": "https://www.ensembl.org/id/ENSGALP00010009104.1" } ] } }, { "isoform_ac": "A0A8V0XT03-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD5/entry#A0A8V0XT03-1", "sequence": { "sequence": "MYGKGKSNSSVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMSGLGGMDSHHMNGSLGSGDMDSISKNSPSNMSMSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 345, "header": "tr|A0A8V0XT03-1|F1NTD5_CHICK Computationally mapped isoform of Single stranded DNA binding protein 2 OS=Gallus gallus OX=9031 GN=SSBP2 PE=4 SV=1 CANONICAL=F1NTD5-1" }, "locus": { "chromosome": "Z", "start_pos": 64409472, "end_pos": 64244541, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015665.1", "url": "https://www.ensembl.org/id/ENSGALT00010015665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009102.1", "url": "https://www.ensembl.org/id/ENSGALP00010009102.1" } ] } }, { "isoform_ac": "F1NTD5-1", "url": "https://www.uniprot.org/uniprotkb/F1NTD5/entry#F1NTD5-1", "sequence": { "sequence": "MYGKGKSNSSVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMSGLGGMDSHHMNGSLGSGDMDSISKNSPSNMSMSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 360, "header": "tr|F1NTD5-1|F1NTD5_CHICK Isoform 1 of Single stranded DNA binding protein 2 OS=Gallus gallus OX=9031 GN=SSBP2 PE=4 SV=2 CANONICAL=F1NTD5-1" }, "locus": { "chromosome": "Z", "start_pos": 64409472, "end_pos": 64244541, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015670.1", "url": "https://www.ensembl.org/id/ENSGALT00010015670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009107.1", "url": "https://www.ensembl.org/id/ENSGALP00010009107.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770958", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770958", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NTD5", "url": "https://www.uniprot.org/uniprotkb/F1NTD5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "F1NTD5", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0036444", "evidence": [ { "database": "UniProtKB", "id": "E1C179", "url": "https://www.uniprot.org/uniprotkb/E1C179" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial calcium ion concentration", "id": "GO:0051562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051562", "evidence": [ { "database": "UniProtKB", "id": "E1C179", "url": "https://www.uniprot.org/uniprotkb/E1C179" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "E1C179", "url": "https://www.uniprot.org/uniprotkb/E1C179" } ], "pmid": "" }, { "name": "mitochondrial calcium ion homeostasis", "id": "GO:0051560", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051560", "evidence": [ { "database": "UniProtKB", "id": "E1C179", "url": "https://www.uniprot.org/uniprotkb/E1C179" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial calcium ion concentration", "id": "GO:0051561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051561", "evidence": [ { "database": "UniProtKB", "id": "E1C179", "url": "https://www.uniprot.org/uniprotkb/E1C179" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C179-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 443, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C179-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C179" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C179", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C179" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 217, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 115 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 321, "end_pos": 323 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLX3-1", "uniprot_ac": "F1NLX3", "uniprot_id": "F1NLX3_CHICK", "mass": { "chemical_mass": 69475.0, "monoisotopic_mass": 69475.0 }, "refseq": { "ac": "XP_414213", "name": "zinc finger protein 276", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414213" }, "gene_names": [ { "name": "ZNF276", "type": "recommended", "evidence": [ { "id": "F1NLX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ] }, { "name": "ZNF276", "type": "synonym", "evidence": [ { "id": "XP_414213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414213" } ] } ], "protein_names": [ { "name": "Zinc finger protein 276", "type": "recommended", "evidence": [ { "id": "F1NLX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLX3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 276", "type": "synonym", "evidence": [ { "id": "XP_414213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414213" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_414213.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414213" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF276", "url": "https://www.uniprot.org/uniprotkb/F1NLX3", "locus": { "chromosome": "11", "start_pos": 18426010, "end_pos": 18418883, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008073", "url": "https://www.ensembl.org/id/ENSGALG00010008073" } ] } } ], "crossref": [ { "id": "F1NLX3", "url": "https://alphafold.ebi.ac.uk/entry/F1NLX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000513", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000513", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415853", "url": "https://www.ncbi.nlm.nih.gov/gene/415853", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415853", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415853", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LAVKWAW", "url": "https://omabrowser.org/oma/group/LAVKWAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XRF3", "url": "https://www.orthodb.org/?gene=A0A8V0XRF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLX3", "url": "https://www.orthodb.org/?gene=F1NLX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XRF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XRF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLX3-1", "url": "https://www.uniprot.org/uniprotkb/F1NLX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRDRRGRFLAAAGGPAAASPEPRKRPAARGSAEGEAGPEPTAGWAPVAAEDSAWARPGGAAEAGIGRALSTGYCRLCHGKFSSRSLRNAFGKVPVMGENSEKQRRVDQVFFTDFQRLVGVAVRQDPALPQFVCKKCHAQFYKCRSVLRTFIQRVNASPTGHVKSKGKSGAAPAQPGVEGGASCLVDLITSSPQCLHSLVTWAHAHAGGCQSVPSLQSVLSSEYCGIIRAVWGCGDGHDYIMDTDSDCSTVLVDNALAVKREWNKSVAQRLTDNGADNAEAVSAPKPQHAPVRTTPCQQPTNKGTTTVPLKLENEPSQNRDSSHSQLDSTASLQEKALPQPVSPLSSTTGQLSGKQVLSATSDERVKDEFSDLSEGDFLSDDEMEKRNVQSSDDSFEPYPEKKVSSKKSDSKEAKKAEEPKVRKKPGPKPGWKKKIKCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLSVHQMRHSGAKPLQCEICGFQCRQRASLKYHMTKHKAETELEFACDQCGKRFEKAHNLNVHMSMVHPLTQTQDKTKPLESESILLLNTSGTSESQAVKPEVTAQQEPT", "length": 632, "header": "tr|F1NLX3-1|F1NLX3_CHICK Isoform 1 of Zinc finger protein 276 OS=Gallus gallus OX=9031 GN=ZNF276 PE=4 SV=4 CANONICAL=F1NLX3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XRF3-1", "url": "https://www.uniprot.org/uniprotkb/F1NLX3/entry#A0A8V0XRF3-1", "sequence": { "sequence": "MGENSEKQRRVDQVFFTDFQRLVGVAVRQDPALPQFVCKKCHAQFYKCRSVLRTFIQRVNASPTGHVKSKGKSGAAPAQPGVEGGASCLVDLITSSPQCLHSLVTWAHAHAGGCQSVPSLQSVLSSEYCGIIRAVWGCGDGHDYIMDTDSDCSTVLVDNALAVKREWNKSVAQRLTDNGADNAEAVSAPKPQHAPVRTTPCQQPTNKGTTTVPLKLENEPSQNRDSSHSQLDSTASLQEKALPQPVSPLSSTTGQLSGKQVLSATSDERRLLER", "length": 274, "header": "tr|A0A8V0XRF3-1|F1NLX3_CHICK Computationally mapped isoform of Zinc finger protein 276 OS=Gallus gallus OX=9031 GN=ZNF276 PE=4 SV=1 CANONICAL=F1NLX3-1" }, "locus": { "chromosome": "11", "start_pos": 18423442, "end_pos": 18420238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019250.1", "url": "https://www.ensembl.org/id/ENSGALT00010019250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010798.1", "url": "https://www.ensembl.org/id/ENSGALP00010010798.1" } ] } }, { "isoform_ac": "F1NLX3-1", "url": "https://www.uniprot.org/uniprotkb/F1NLX3/entry#F1NLX3-1", "sequence": { "sequence": "MKRDRRGRFLAAAGGPAAASPEPRKRPAARGSAEGEAGPEPTAGWAPVAAEDSAWARPGGAAEAGIGRALSTGYCRLCHGKFSSRSLRNAFGKVPVMGENSEKQRRVDQVFFTDFQRLVGVAVRQDPALPQFVCKKCHAQFYKCRSVLRTFIQRVNASPTGHVKSKGKSGAAPAQPGVEGGASCLVDLITSSPQCLHSLVTWAHAHAGGCQSVPSLQSVLSSEYCGIIRAVWGCGDGHDYIMDTDSDCSTVLVDNALAVKREWNKSVAQRLTDNGADNAEAVSAPKPQHAPVRTTPCQQPTNKGTTTVPLKLENEPSQNRDSSHSQLDSTASLQEKALPQPVSPLSSTTGQLSGKQVLSATSDERVKDEFSDLSEGDFLSDDEMEKRNVQSSDDSFEPYPEKKVSSKKSDSKEAKKAEEPKVRKKPGPKPGWKKKIKCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLSVHQMRHSGAKPLQCEICGFQCRQRASLKYHMTKHKAETELEFACDQCGKRFEKAHNLNVHMSMVHPLTQTQDKTKPLESESILLLNTSGTSESQAVKPEVTAQQEPT", "length": 632, "header": "tr|F1NLX3-1|F1NLX3_CHICK Isoform 1 of Zinc finger protein 276 OS=Gallus gallus OX=9031 GN=ZNF276 PE=4 SV=4 CANONICAL=F1NLX3-1" }, "locus": { "chromosome": "11", "start_pos": 18425533, "end_pos": 18418892, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019252.1", "url": "https://www.ensembl.org/id/ENSGALT00010019252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010800.1", "url": "https://www.ensembl.org/id/ENSGALP00010010800.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415853", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415853", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IC99-1", "protein_name": "Zinc finger protein 276", "gene_name": "Znf276", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKRDRLGRFLSPGTARQRGSSGGSCGSGRTRGRPSRTGAASADGAAALAAAQLSWGSTRSCGDTGEDGTDEAGAGRTLAMGHCRLCHGKFSSRSLRSISDRVPGETSERLSPGERVFIRDFQRLLGVAVHQDPALPQFVCKNCYTQFYQCHSLLRSFLQRVNVSPAGQRKPCTKVGVQPPTVAEEGACMADLITSSPRCLHSLVGWVHEHAANCGSLPSLQRTLSSEYCGIIQAVWGCDQGHDFTMDTDSSCRALLLDSALAVKWAWGKEMSPRLSQSSELNTTGAASQLCQARGTQVGSETKTPPSVDVALLHSHGDSVGPGIGPYTQPNLAPSEAPGQLGEKQVPSSTSDDRVKDEFSDLSEGDFLSEDENDKKQNPQSSDESFEPYPEKKVSGKKSESKEAKKPEEPKIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEICGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKVLPLEAEPPPGPLSLSGTMEGQAVKPEPT", "length": 617 }, "evidence": [ { "id": "F1NLX3", "url": "https://omabrowser.org/oma/group/F1NLX3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M9PUR8-1", "protein_name": "Zinc finger protein 276", "gene_name": "znf276", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRRRGTRTSRRETRDHSSGRSSSSFCRLCHGKFSRRRLLQAFAQLQGEACGGVYPLFCADFQQLLGIRMERDPALSQFICTGCHAQFYRCHSILLQFRSRVNLTPPTAHSYNDAVSSRSGAEHSSSQEDISLIRSQMPWDRRCLLSLVSWAHGHAEGCSSCPGLQEVLEGPCGGALRAVWGCGDGHSYVMDSGAAASTHTTEDHTDEHAQPTHQQGAALSGSDPLRSAEPQNHSDTHDTQCSEQTDASLTPAPAEDADSELSDRNMLSDEECEEQRKSGSSEDSDPHTDKRSSKRKETKTPEPKTRRKPGPKPGWKNSSKSEREELPTIYKCPHQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDQCGQTFKQRKHLSVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAEADLEFACVICGKRFEKAHNLNVHMSMVHPLMQSAGATVPADPPLTHS", "length": 492 }, "evidence": [ { "id": "F1NLX3", "url": "https://omabrowser.org/oma/group/F1NLX3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1B6Y2-1", "protein_name": "Zinc finger protein 276", "gene_name": "ZNF276", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKRDRLGRFLSPAASRQRGSSGRGSCGGGRVRGRPARSGPDVAEAAAVVAARLGWGPARPCGDAGEDGADEAGTARALAMGHCRLCHGKFSSRSLRSISGRAPGESSERPPPGDRVFIRDFQRLLGVAVHQDPALSQFICKNCHAQFYQCHGLLTSFLQRVNVPPTGRRKPCAKVGVQPRMGPEEGACVVDLIASSPQGLRGLVGWVHRHAAGCGALPSLQRTLSSEYCGVIRAMWGCDQGHDYTMDADSSCGALLLDSALGVKWTWDKDSAPRLPQHRGFNPTGAAPQSSQGKAAAAGAETETLPSMDTSRLPSDGDPVGPGPGPPSQPSLPPGGAPGQLGEKQVPSPTSDDRVKDEFSDLSEGDFLSEDENDKKQNTQSSDESFEPYPGKKVSGRKSESKEAKKSEEPKIRKKPGPKPGWKGKPRCEREELPTIYKCPHQGCTAVYRGADGMKKHVKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQAPEAPPRPAAGQVVKAEPT", "length": 603 }, "evidence": [ { "id": "F1NLX3", "url": "https://omabrowser.org/oma/group/F1NLX3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LN08-1", "protein_name": "Zinc finger protein 276", "gene_name": "Zfp276", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRDRLGRFLSPGIARQRGSSGSSCGSGRTRGRPSRTGGSSADGAAPQLSWGSTRSCGDTGEDGTDEAGAGRTLTMGHCRLCHGKFSSRSLRSISERVPGETSERLSPGERVFIRDFQRLLGVAVHQDPALPQFVCKNCYTQFYQCHSLLRSFLQRVNVSPAGQRKPCTKVGVQPPTVAEEGACMADLITSSPQCLHGLVGWVHEHAVNCGCLPSLQRTLSSEYCGVIQAVWGCDQGHDFTMDTDSGCRALLLDSALAVKWGKELAPRLAQSSASDPTGAASQLCQARETQVGSETKTLPSVDVALLHSHGDSVGPGLSPYIQPNLAPSEAPGQLGEKQVPSSTSDDRVKDEFSDLSEGDVLSEDDSDKKQTPQSSDESFEPYPEKKVSGKKSEGKEAKRPEEPKIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQALPLEAEPPPGPLSLAGTVEGQAVKPEPT", "length": 609 }, "evidence": [ { "id": "F1NLX3", "url": "https://omabrowser.org/oma/group/F1NLX3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CE64-1", "protein_name": "Zinc finger protein 276", "gene_name": "Znf276", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRDRLGRFLSPGIARQRGGSGGGCGSGRTRGRPSRSGGTSADGAAAQLSWGSMTRSCGDTGDDGTDEAGAGRTLAMGHCRLCHGKFSSRSLRSISDRVPGETSERLSPGERVFIRDFQRLLGVAVHQDPALPQSVCKNCYTQFYQCHSLLRTFLQRVNVSPAGQRKPCTKVGVQPTTVAEEGACVADLIASSPRCLHGLVGWVHEHAVSCGSLPSLQRTLSSEYCGIIQAVWGCDQGHDFTMDTASSCRALFLDSALAVKWAWGKDLSPRLAQNSESNPTGAASRLCQARETQVGSETKTLPSVDVALLHSHGDSVGPGLGPCTQPHLAPSEAPGQLGETQVPSSTSDDRVKDEFSDLSEGDFLSEDESDKKQTPQSSDESFEPYPEKKVSGKKSEGREAKRPEEPKIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQAQDRALPLEAEPPPGPLSPSGTMEGQAVKPEPT", "length": 614 }, "evidence": [ { "id": "F1NLX3", "url": "https://omabrowser.org/oma/group/F1NLX3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N554-1", "protein_name": "Zinc finger protein 276", "gene_name": "ZNF276", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRDRLGRFLSPGSSRQCGASDGGGGVSRTRGRPSLSGGPRVDGATARRAWGPVGSCGDAGEDGADEAGAGRALAMGHCRLCHGKFSSRSLRSISERAPGASMERPSAEERVLVRDFQRLLGVAVRQDPTLSPFVCKSCHAQFYQCHSLLKSFLQRVNASPAGRRKPCAKVGAQPPTGAEEGACLVDLITSSPQCLHGLVGWVHGHAASCGALPHLQRTLSSEYCGVIQVVWGCDQGHDYTMDTSSSCKAFLLDSALAVKWPWDKETAPRLPQHRGWNPGDAPQTSQGRGTGTPVGAETKTLPSTDVAQPPSDSDAVGPRSGFPPQPSLPLCRAPGQLGEKQLPSSTSDDRVKDEFSDLSEGDVLSEDENDKKQNAQSSDESFEPYPERKVSGKKSESKEAKKSEEPRIRKKPGPKPGWKKKLRCEREELPTIYKCPYQGCTAVYRGADGMKKHIKEHHEEVRERPCPHPGCNKVFMIDRYLQRHVKLIHTEVRNYICDECGQTFKQRKHLLVHQMRHSGAKPLQCEVCGFQCRQRASLKYHMTKHKAETELDFACDQCGRRFEKAHNLNVHMSMVHPLTQTQDKALPLEAEPPPGPPSPSVTTEGQAVKPEPT", "length": 614 }, "evidence": [ { "id": "F1NLX3", "url": "https://omabrowser.org/oma/group/F1NLX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1NLX3", "url": "https://www.uniprot.org/uniprotkb/F1NLX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NLX3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 632, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NLX3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NLX3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 42 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 611, "end_pos": 613 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C008-1", "uniprot_ac": "E1C008", "uniprot_id": "E1C008_CHICK", "mass": { "chemical_mass": 54896.0, "monoisotopic_mass": 54896.0 }, "refseq": { "ac": "XP_015137616", "name": "WD repeat-containing protein 37", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137616" }, "gene_names": [ { "name": "WDR37", "type": "recommended", "evidence": [ { "id": "E1C008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C008" } ] }, { "name": "WDR37", "type": "synonym", "evidence": [ { "id": "XP_015137616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137616" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 37", "type": "recommended", "evidence": [ { "id": "E1C008", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C008/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 37", "type": "synonym", "evidence": [ { "id": "XP_015137616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137616" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137616" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C008", "url": "https://www.uniprot.org/uniprotkb/E1C008" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR37", "url": "https://www.uniprot.org/uniprotkb/E1C008", "locus": { "chromosome": "2", "start_pos": 10424217, "end_pos": 10385705, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005552", "url": "https://www.ensembl.org/id/ENSGALG00010005552" } ] } } ], "crossref": [ { "id": "E1C008", "url": "https://alphafold.ebi.ac.uk/entry/E1C008", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006749", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006749", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420460", "url": "https://www.ncbi.nlm.nih.gov/gene/420460", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420460", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420460", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TACIWGV", "url": "https://omabrowser.org/oma/group/TACIWGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XI61", "url": "https://www.orthodb.org/?gene=A0A8V0XI61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XMC4", "url": "https://www.orthodb.org/?gene=A0A8V0XMC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSB9", "url": "https://www.orthodb.org/?gene=A0A8V0XSB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C008", "url": "https://www.orthodb.org/?gene=E1C008", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19855", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19855", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19855:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19855:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015137616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XI61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XI61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C008", "url": "https://www.uniprot.org/uniprotkb/E1C008", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C008-1", "url": "https://www.uniprot.org/uniprotkb/E1C008-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIESGSCASARQAKQKRKSHSLSIRRTNSSEQERAGLQRDMLEGQDSKLPSSVRNTLLELFGQIEREFENLYIENLELRREIDTLNERLAAEGQTIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYVGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYVGHVGSVNSIKFHPTEQVALTASGDQTAHIWRYIVQLPTPQPTADCNQVSGEDEFEFSDKDEPDGDGDGSSDCPTVRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAVNRINVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSNRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK", "length": 495, "header": "tr|E1C008-1|E1C008_CHICK Isoform 1 of WD repeat-containing protein 37 OS=Gallus gallus OX=9031 GN=WDR37 PE=1 SV=1 CANONICAL=E1C008-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XI61-1", "url": "https://www.uniprot.org/uniprotkb/E1C008/entry#A0A8V0XI61-1", "sequence": { "sequence": "MPIESGSCASARQAKQKRKSHSLSIRRTNSSEQERAGLQRDMLEGQDSKLPSSVRNTLLELFGQIEREFENLYIENLELRREIDTLNERLAAEGQTIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYVGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYVGHVGSVNSIKFHPTEQVALTASGDQTAHIWRYIVQLPTPQPTADCNVSNQLAAIICTAI", "length": 255, "header": "tr|A0A8V0XI61-1|A0A8V0XI61_CHICK Computationally mapped isoform of WD repeat-containing protein 37 OS=Gallus gallus OX=9031 GN=WDR37 PE=1 SV=1 CANONICAL=E1C008-1" }, "locus": { "chromosome": "2", "start_pos": 10407713, "end_pos": 10394213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013280.1", "url": "https://www.ensembl.org/id/ENSGALT00010013280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007842.1", "url": "https://www.ensembl.org/id/ENSGALP00010007842.1" } ] } }, { "isoform_ac": "A0A8V0XMC4-1", "url": "https://www.uniprot.org/uniprotkb/E1C008/entry#A0A8V0XMC4-1", "sequence": { "sequence": "MPIESGSCASARQAKQKRKSHSLSIRRTNSSEQERAGLQRDMLEGQDSKLPSSVRNTLLELFGQIEREFENLYIENLELRREIDTLNERLAAEGQTIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYVGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYVGHVGSVNSIKFHPTEQVALTASGDQTAHIWRYIVQLPTPQPTADCNQVSGEDEFEFSDKDEPDGDGDGSSDCPTVRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAVNRINVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSNRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK", "length": 491, "header": "tr|A0A8V0XMC4-1|A0A8V0XMC4_CHICK Computationally mapped isoform of WD repeat-containing protein 37 OS=Gallus gallus OX=9031 GN=WDR37 PE=1 SV=1 CANONICAL=E1C008-1" }, "locus": { "chromosome": "2", "start_pos": 10420868, "end_pos": 10394213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013284.1", "url": "https://www.ensembl.org/id/ENSGALT00010013284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007846.1", "url": "https://www.ensembl.org/id/ENSGALP00010007846.1" } ] } }, { "isoform_ac": "A0A8V0XSB9-1", "url": "https://www.uniprot.org/uniprotkb/E1C008/entry#A0A8V0XSB9-1", "sequence": { "sequence": "HVVNINAISQWSYKQHEIWDSKLPSSVRNTLLELFGQIEREFENLYIENLELRREIDTLNERLAAEGQTIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYVGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYVGHVGSVNSIKFHPTEQVALTASGDQTAHIWRYIVQLPTPQPTADCNQVSGEDEFEFSDKDEPDGDGDGSSDCPTVRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAVNRINVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSNRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK", "length": 468, "header": "tr|A0A8V0XSB9-1|E1C008_CHICK Computationally mapped isoform of WD repeat-containing protein 37 OS=Gallus gallus OX=9031 GN=WDR37 PE=1 SV=1 CANONICAL=E1C008-1" }, "locus": { "chromosome": "2", "start_pos": 10420868, "end_pos": 10395169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013283.1", "url": "https://www.ensembl.org/id/ENSGALT00010013283.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007845.1", "url": "https://www.ensembl.org/id/ENSGALP00010007845.1" } ] } }, { "isoform_ac": "E1C008-1", "url": "https://www.uniprot.org/uniprotkb/E1C008/entry#E1C008-1", "sequence": { "sequence": "MPIESGSCASARQAKQKRKSHSLSIRRTNSSEQERAGLQRDMLEGQDSKLPSSVRNTLLELFGQIEREFENLYIENLELRREIDTLNERLAAEGQTIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYVGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYVGHVGSVNSIKFHPTEQVALTASGDQTAHIWRYIVQLPTPQPTADCNQVSGEDEFEFSDKDEPDGDGDGSSDCPTVRAPLTSLKSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAVNRINVCVGQRIIALPHDNRQVRLFDMSGVRLARLPRSNRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK", "length": 495, "header": "tr|E1C008-1|E1C008_CHICK Isoform 1 of WD repeat-containing protein 37 OS=Gallus gallus OX=9031 GN=WDR37 PE=1 SV=1 CANONICAL=E1C008-1" }, "locus": { "chromosome": "2", "start_pos": 10420868, "end_pos": 10394213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013288.1", "url": "https://www.ensembl.org/id/ENSGALT00010013288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007850.1", "url": "https://www.ensembl.org/id/ENSGALP00010007850.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420460", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420460", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LE87-1", "protein_name": "WD repeat-containing protein 37", "gene_name": "Wdr37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTESGSCSTARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIDSLNERLAGEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYIGHRDGIWDVSVARTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDLDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK", "length": 496 }, "evidence": [ { "id": "E1C008", "url": "https://omabrowser.org/oma/group/E1C008/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FEE4-1", "protein_name": "WD repeat-containing protein 37", "gene_name": "wdr37", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPVESGNSAAARQVKQKRKSHSLSIRRTNSTEQDRTGMQRDMLEGQDSKLPMALRSNLLDLFGQIEREFENLYIENLELRREIESLNERLSGEGQTVEGGDLSKGALKTKASHSTSQLSQKLKTTYKASTSKIVSSFKATTSRAVCQLVKEYVGHRDGIWDLAVTRVQPLVLGTASADHCSMLWSIETGKCLLKYAGHAGSVNSIKFHPTEQMALTASGDQTAHIWRYMVQLPLPQPPADISASLDDDVDFSDKDEADGDADGPNECPTIRVATTTLKSHQGVVIAADWLVGGKQVVTASWDRAANLYDVETSELVHTLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAVNRISVSANQRIIALPHDNRQVRLFDMNGVRLARLPRSNRQGHRRMVCCSAWNEENQACNLFTCGFDRQAIGWNINIPALLQEK", "length": 494 }, "evidence": [ { "id": "E1C008", "url": "https://omabrowser.org/oma/group/E1C008/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3GR89-1", "protein_name": "WD repeat-containing protein 37", "gene_name": "Wdr37", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPTESGSCSTARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIDTLNERLAGEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYIGHRDGIWDVSVARTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK", "length": 496 }, "evidence": [ { "id": "E1C008", "url": "https://omabrowser.org/oma/group/E1C008/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CBE3-1", "protein_name": "WD repeat-containing protein 37", "gene_name": "Wdr37", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTESGSCSTARQAKQKRKSHSLSIRRTNSSEQERTGLPREMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIDTLNERLAGEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAICQLVKEYIGHRDGIWDVSVTRTQPIVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYVVQLPTPQPVADTSQQISGEDEIECSDKDEPDIDGDVSSDCPTVRVPLTSLKSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPICNLFTCGFDRQAIGWNINIPALLQEK", "length": 496 }, "evidence": [ { "id": "E1C008", "url": "https://omabrowser.org/oma/group/E1C008/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VE73-1", "protein_name": "WD repeat-containing protein 37", "gene_name": "Wdr37", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKASKTRAVRLTSLTEDVAAVPEDAPFRARLHVLFAQIEREFEQLYLENQALQEKLDIATTTKESLIPPDARSAAGGSMSTQASSAALATPATQTDEVAGSFLAAASSTHKSLKAKLSSATGGSKAKASNKIKAQTSRIVSSFKAPTVVSTVVREFGGHKDGIWQVAAKAGQPIIGTASADHTACIWGVESARCLLQYQGHAGSVNSIKFHQQRDLVLTGSGDGTAHIWQAAVNWEVPKKGHSSEEELDDSDEQVEDRDRVDTLRTPLCEFTGPGGHLSVVVAADWLSSMDQIITGSWDRTAILWDVETGLPLQPLTGHDHELTHVSAHPTQRLVVTASRDTTFRLWDFREAIPAVSVFQGHTETVTSSVFARDDKVVSGSDDRTIKVWELRNMRSALATIRTDSSVNRLAVSTGGIIAIPHDNRQIRLFDLNGQRVARLPRTSRQGHRRMVSSVAWAEEPLLDCDLFSCGFDRRVFGWSIVLPKDN", "length": 487 }, "evidence": [ { "id": "E1C008", "url": "https://omabrowser.org/oma/group/E1C008/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2I8-1", "protein_name": "WD repeat-containing protein 37", "gene_name": "WDR37", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPTESASCSTARQTKQKRKSHSLSIRRTNSSEQERTGLPRDMLEGQDSKLPSSVRSTLLELFGQIEREFENLYIENLELRREIDTLNERLAAEGQAIDGAELSKGQLKTKASHSTSQLSQKLKTTYKASTSKIVSSFKTTTSRAACQLVKEYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHPSEQLALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDNVVSGSDDRTVKVWDLKNMRSPIATIRTDSAINRINVCVGQKIIALPHDNRQVRLFDMSGVRLARLPRSSRQGHRRMVCCSAWSEDHPVCNLFTCGFDRQAIGWNINIPALLQEK", "length": 494 }, "evidence": [ { "id": "E1C008", "url": "https://omabrowser.org/oma/group/E1C008/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C008", "url": "https://www.uniprot.org/uniprotkb/E1C008" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C008", "url": "https://www.uniprot.org/uniprotkb/E1C008" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lymphocyte homeostasis", "id": "GO:0002260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002260", "evidence": [ { "database": "UniProtKB", "id": "E1C008", "url": "https://www.uniprot.org/uniprotkb/E1C008" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C008-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 495, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C008-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C008" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NHD9-1", "uniprot_ac": "F1NHD9", "uniprot_id": "F1NHD9_CHICK", "mass": { "chemical_mass": 86182.0, "monoisotopic_mass": 86182.0 }, "refseq": { "ac": "NP_001006384", "name": "exocyst complex component 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006384" }, "gene_names": [ { "name": "EXOC3", "type": "recommended", "evidence": [ { "id": "F1NHD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ] }, { "name": "EXOC3", "type": "synonym", "evidence": [ { "id": "NP_001006384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006384" } ] }, { "name": "SEC6L1", "type": "synonym", "evidence": [ { "id": "NP_001006384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006384" } ] } ], "protein_names": [ { "name": "Exocyst complex component 3", "type": "recommended", "evidence": [ { "id": "F1NHD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHD9/entry#names_and_taxonomy" } ] }, { "name": "Exocyst complex component Sec6", "type": "synonym", "evidence": [ { "id": "F1NHD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHD9/entry#names_and_taxonomy" } ] }, { "name": "SEC6-like 1", "type": "synonym", "evidence": [ { "id": "NP_001006384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006384" } ] }, { "name": "exocyst complex component 3", "type": "synonym", "evidence": [ { "id": "NP_001006384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006384" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720579.1, ERR2365565.149036.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000042.1. On Sep 23, 2021 this sequence version replaced NP_001006384.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006384" } ] }, { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9#function" }, { "database": "UniProtKB", "id": "ARBA00002660", "url": "https://www.uniprot.org/uniprotkb/ARBA00002660#function" }, { "database": "UniProtKB", "id": "A0A8V0XSE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSE9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOC3", "url": "https://www.uniprot.org/uniprotkb/F1NHD9", "locus": { "chromosome": "2", "start_pos": 88542101, "end_pos": 88524306, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008189", "url": "https://www.ensembl.org/id/ENSGALG00010008189" } ] } } ], "crossref": [ { "id": "F1NHD9", "url": "https://alphafold.ebi.ac.uk/entry/F1NHD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013397", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013397", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420987", "url": "https://www.ncbi.nlm.nih.gov/gene/420987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420987", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNIGPKT", "url": "https://omabrowser.org/oma/group/MNIGPKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSE9", "url": "https://www.orthodb.org/?gene=A0A8V0XSE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NHD9", "url": "https://www.orthodb.org/?gene=F1NHD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21292:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21292:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-264876", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006384", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XSE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NHD9-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLIDVNKDWRQSINAIENLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIERGELLQAHRKLMDLECSRDNLMYEQYRMDSKNTHDMNLIHTYFGDMQKLSEELAKQLWMVVQRSLVTVRRDPTLLVSVVRIIEREEKIDRRMLDRKKQTGFIPPGRPKKWKENMFNILERTVSIRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLLVAKTLLDQCFPPHYDIFKRLLSMYHQALSTRMQELAAEDLEANEIVSLLTWVLNTYKSTEMMGNSELSPEVDANSLDLLLSQNVVDQLLSKYMSTLTSNIIGWLRKALETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLLLCLQQMNSFLTRYKDEAQFYKEEHLKNRQYPQCYVQYMIAVINNCQTFKESIISLKRKYLKVEMEETLSSSHASMDAILDIIAKEGCSSLLDEVFMDLEPHLNELMTKKWLLGSNAVGTICVTVEDYFNDFAKIKKPYKKTMTMEAHRRVVVEYIRAIMLKRISFKNAEERKEGAEKMIKEAEQFRFLFKKLASGSGEDTEGLCDIIEAIAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIAALLTVRGDASRDMKQTIIETLDQGPSQPNPNYVPIFKEITVPTLTVPKLLK", "length": 745, "header": "tr|F1NHD9-1|F1NHD9_CHICK Isoform 1 of Exocyst complex component 3 OS=Gallus gallus OX=9031 GN=EXOC3 PE=1 SV=2 CANONICAL=F1NHD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XSE9-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD9/entry#A0A8V0XSE9-1", "sequence": { "sequence": "MKTFKQERTVDPDEQGRRQAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLIDVNKDWRQSINAIENLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIERGELLQAHRKLMDLECSRDNLMYEQYRMDSKNTHDMNLIHTYFGDMQKLSEELAKQLWMVVQRSLVTVRRDPTLLVSVVRIIEREEKIDRRMLDRKKQTGFIPPGRPKKWKENMFNILERTVSIRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLLVAKTLLDQCFPPHYDIFKRLLSMYHQALSTRMQELAAEDLEANEIVSLLTWVLNTYKSTEMMGNSELSPEVDANSLDLLLSQNVVDQLLSKYMSTLTSNIIGWLRKALETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLLLCLQQMNSFLTRYKDEAQFYKEEHLKNRQYPQCYVQYMIAVINNCQTFKESIISLKRKYLKVEMEETLSSSHASMDAILDIIAKEGCSSLLDEVFMDLEPHLNELMTKKWLLGSNAVGTICVTVEDYFNDFAKIKKPYKKTMTMEAHRRVVVEYIRAIMLKRISFKNAEERKEGAEKMIKEAEQFRFLFKKLASGSGEDTEGLCDIIEAIAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIAALLTVRGDASRDMKQTIIETLDQGPSQPNPNYVPIFKEITVPTLTVPKLLK", "length": 716, "header": "tr|A0A8V0XSE9-1|F1NHD9_CHICK Computationally mapped isoform of Exocyst complex component 3 OS=Gallus gallus OX=9031 GN=EXOC3 PE=1 SV=1 CANONICAL=F1NHD9-1" }, "locus": { "chromosome": "2", "start_pos": 88541562, "end_pos": 88526916, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019580.1", "url": "https://www.ensembl.org/id/ENSGALT00010019580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011128.1", "url": "https://www.ensembl.org/id/ENSGALP00010011128.1" } ] } }, { "isoform_ac": "F1NHD9-1", "url": "https://www.uniprot.org/uniprotkb/F1NHD9/entry#F1NHD9-1", "sequence": { "sequence": "MEETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLIDVNKDWRQSINAIENLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIERGELLQAHRKLMDLECSRDNLMYEQYRMDSKNTHDMNLIHTYFGDMQKLSEELAKQLWMVVQRSLVTVRRDPTLLVSVVRIIEREEKIDRRMLDRKKQTGFIPPGRPKKWKENMFNILERTVSIRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLLVAKTLLDQCFPPHYDIFKRLLSMYHQALSTRMQELAAEDLEANEIVSLLTWVLNTYKSTEMMGNSELSPEVDANSLDLLLSQNVVDQLLSKYMSTLTSNIIGWLRKALETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLLLCLQQMNSFLTRYKDEAQFYKEEHLKNRQYPQCYVQYMIAVINNCQTFKESIISLKRKYLKVEMEETLSSSHASMDAILDIIAKEGCSSLLDEVFMDLEPHLNELMTKKWLLGSNAVGTICVTVEDYFNDFAKIKKPYKKTMTMEAHRRVVVEYIRAIMLKRISFKNAEERKEGAEKMIKEAEQFRFLFKKLASGSGEDTEGLCDIIEAIAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIAALLTVRGDASRDMKQTIIETLDQGPSQPNPNYVPIFKEITVPTLTVPKLLK", "length": 745, "header": "tr|F1NHD9-1|F1NHD9_CHICK Isoform 1 of Exocyst complex component 3 OS=Gallus gallus OX=9031 GN=EXOC3 PE=1 SV=2 CANONICAL=F1NHD9-1" }, "locus": { "chromosome": "2", "start_pos": 88541562, "end_pos": 88525881, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019587.1", "url": "https://www.ensembl.org/id/ENSGALT00010019587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011135.1", "url": "https://www.ensembl.org/id/ENSGALP00010011135.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420987", "resource": "KEGG Pathway" }, { "id": "R-GGA-264876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "resource": "Reactome", "description": "Insulin processing" }, { "id": "R-GGA-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FDH7-1", "protein_name": "Exocyst complex component 3", "gene_name": "Exoc3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEIPCHFLPPGSLCSVYLWHDMCKDSACLLTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRRETRKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDELMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFAILDRTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIIAKNLMVQCFPPHYEIFKNLLSMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVSALEPLLSSNVVSELLDTYMSTLTSNIIAWLRKALETDKKDWSKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKEEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKTEAEEGPCLSQPSMDGILDAIAKEGCSSLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFARIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPMQASPNYVPIFKEIVVPSLNVAKLLK", "length": 776 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60645-1", "protein_name": "Exocyst complex component 3", "gene_name": "EXOC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFTILERTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQCFPPHYEIFKNLLNMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSTEMMRNVELAPEVDVGTLEPLLSPHVVSELLDTYMSTLTSNIIAWLRKALETDKKDWVKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIVSLKRKYLKNEVEEGVSPSQPSMDGILDAIAKEGCSGLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSPEERKEGAEKMVREAEQLRFLFRKLASGFGEDVDGYCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAVRGDASRDMKQTIMETLEQGPAQASPSYVPLFKDIVVPSLNVAKLLK", "length": 745 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32844-1", "protein_name": "Exocyst complex component SEC6", "gene_name": "SEC6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSDPLQQVCDLIKGDLSLERVRDIKEQLLKEKSVVEYQLNKESDKYYGEVEESLKLLNLSKNSVTSIKQQINEVNKLGNDNRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIERLLVAELAEDALETGCPHLLEIHFLLTSARDFQEQVVVMAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKKEIEIEKSSIKKLPNSKNTARLQDETPKVIEYPTNKGLYQEIMSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVGDQKFDVLDNMDWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVESEPETIIILDILAFDKTFQDTLKQDFGFTKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAGTNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNHKYDIDPESITPEDECPGGLVEYLIAVSNDQMKAADYAVAISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGSQAQQIADTLDEYLLDIKPQMNSVLFVNFIDNVIGETIIKFLTALSFEHSFKNKNNKFLEAMKRDFEIFYQLFVKVLDGNESKDTLITQNFTVMEFFMDLSCEPIDSILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSERKKIVQQATEMLHEYRRNMEANGVDREPTLMRRFVLEFEKQ", "length": 805 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0V8C2-1", "protein_name": "Exocyst complex component 3", "gene_name": "EXOC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKETDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVRHSQLAAAVENLKNIFSVPEIVRETQDLIEHGELLQAHRKLMDLECSRDGLMYEQYRMDSGNTRDMTLIHSYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFTILDRTVTTRIEGTQADTRESDRMWLVRHLEIIRKYVLDDLIVAKNLLAQCFPPHYEIFRSLLRTYHQALSARMQDLAAEDLEANEIVSLLTWVLNTYTSVEMMGNAELAPEVDVALLEPLLSADVVSALLDTYMSTLTSNIIAWLRKALETDKKDWMKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKEEAQLYRDEHLRDRQHPHCYVQYMVAVVNNCQTFKESIVSLKRKYLKHEAEEGVSLSQPSMDGVLDAIAKEGCGSLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYRKRMIAEAHRRAVQEYLRAVMQKRISFRSAEERKDGAERMVREAEQLRFLFRKLASGFGEEMDSYCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLAMRGDASRDMKQTIIETLEQGPAQASPDYVPIFKDIVVPSLNVAKLLK", "length": 745 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54BP6-1", "protein_name": "Exocyst complex component 3", "gene_name": "exoc3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVSLVPLEGLDDLSAQSAAIKKIEQNFSNIDSLASVTNHKISLIQQKKTIEAQIKNEVHSELEKSKKGLETLYKSYNRINRMDESFSDTVELCSETSNLIGHYQLIKKVNTVRVNLINILKEVDRLLTIPEKAAEIEQLLSDDLNLLEIHSKLRELERLHQKALKQFESNFEELEAIKEMFSSVPELSHRFENKIWNIVSNSIDIAQIKPAVLVKVAQIIEREKLHEQKQKEKKSQNSLISSEGIHDDDDDDDDTEVNLNNSNKQQNNENENSSSNNNNNYDINNEDEGYDRNRSNYGDRFLEVLIQSISGKFEPMFLNSHNDLVQTLKDVNKMVDELFIVMDIVQECYPPSYDLFNFYVDQYHTKFYSLFGSFSNLMESSHVNNNYQVVVTKNIPSAHILMLVEWVVKNYSRDLSRLGIQDISPPLLDSLDPLIKIYKMHIKQLMREWCDNIINNDNQNKPEVVDGQYCSLAPIQLFESVASQLDIAAATKCQKLVVGVMEEVVSALMYFQVQSITLLQERNHEIKLENVIAYVNNNSKCYDHTQTIVDKVSNILDSEHMGYLDFDPVLEGFLNVSKVATQAISSVIFRDLDECIHKFYTVEWYQEDLMQPIINTFEDYVTNDIQKYILENYLKRLALLLLDTLIEQLLAQLIGGKNKFNENTYKILSNDCDKLLDFFKKYLRLSVVTAKVQILEDFKQMITSSIDMVPVYFRSVINFHKDINERVVELVLYQRTDISKSEITEVLGQIKTIVETVHTDPTNPPTGIFSRMNIYQRGWFS", "length": 783 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q62825-1", "protein_name": "Exocyst complex component 3", "gene_name": "Exoc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCKDSACFSTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFAVLDRTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLVIAKNLLVQCFPPHYDIFKNLLSMYHQALSIRMQDLASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVNALEPLLSPNVVSELLDTYMSTLTSNIIAWLRKALETDKKDWSKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKEEAQLYKEEHLRNRQHPHCYVQYMVAIINNCQTFKESIISLKRKYLKPETEESLCQSQPSMDGILDAIAKEGCSSLLEEVFLDLEQHLNELMTKKWMLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLALRGDASRDMKQTIMETLEQGPMQASPNYVPIFQEIVVPSLNVAKLLK", "length": 755 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6KAR6-1", "protein_name": "Exocyst complex component 3", "gene_name": "Exoc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCKDSACFLTMKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQLHNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQDLIEQGALLQAHRKLMDLECSRDGLMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAKQLWMVLQRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFAILDRTVTTRIEGTQADTRESDKMWLVRHLEIIRKYVLDDLIVAKNLMVQCFPPHYEIFKNLLSMYHQALSTRMQDLASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVSALEPLLSPNIVSELLDTYMSTLTSNIIAWLRKALETDKKDWSKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLCLQQMNSFLSRYKDEAQLYKEEHLRNRQHPHCYVQYMIAIINNCQTFKESIISLKRKYLKTEAEEGLCLSQPSMDGILDAIAKEGCSSLLEEVFLDLEQHLNELMTKKWLLGSNAVDIICVTVEDYFNDFAKIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAEKMVREAEQLRFLFRKLASGFGEDADGHCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLALRGDASRDMKQTIMETLEQGPMQASPNYVPIFKEIVVPSLNVAKLLK", "length": 755 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94AI6-1", "protein_name": "Exocyst complex component SEC6", "gene_name": "SEC6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMVEDLGVEAKEAAVREVAKLLPLPELLQSISSIKADYIARQQANDAQLSTMVAEQVEQAQAGLESLSSSEKTIYELRDNFISIDKLCQECQTLIDNHDQIKLLSNARNNLNKTLKDVEGMMSISVEAAAARDSLSDDKEIVNTYERLTALDGKRRFALAAAGEEVGRLREYFEDVDRTWETFEKTLWGHVSNYYKLSKESPQTLVRALRVVEMQEILDQQLAEEAAEAEGEGAMASVANPRRPGKKSTTTSASSKGLAQQKLKVQGKGYKDKCYEQIRKAVEDRFNRLLTLVFEDLKAALEEARMIGEELGDIYDYVAPCFPPRYEIFQLMVNLYTERFIQMLRLLSDRANDLTNIEILKVTGWVVEYQENLIALGVDDSLAQVCSESGSMDPLMNAYVERMQATTKKWYMNILEADKVQPPKKTEEGKLYTPAAVDLFRILGEQVQIVRDNSTDVMLYRIALAIIQVMIDFQAAEKKRVDEPASDIGLEPLCAMINNNLRCYDLAMELSNSTLEALPQNYAEQVNFEDTCKGFLEVAKEAVHQTVRVIFEDPGVQELLVKLYQKEWCEGQVTEYLVATFGDYFTDVKMYVEERSFRRFVEACLEETVVVYVDHLLTQKNYIKEETIERMRLDEEVLMDFFREYISASKVESRIRIMSDLRELASAESLDAFTLVYSNILEHQPDCPAEVVEKLVSLREGIPRKDTKEVVQECKEIYENTLVDGNPPKTGFVFPRVKCLTASKGSMWRKLT", "length": 752 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V8K2-1", "protein_name": "Exocyst complex component 3", "gene_name": "Sec6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLQQLEEQARQAALKDIQNMLQRPGQLEKVEQYRHRIARKKASVEALLKTGMQGQLDGVRVGLKQLETCMQDVREVRRRMDEVERLLRGVPEVYDALEVVREENTKHSQYATAMENLKHIFNVDASVQKTMALIEDDKLLNAHQCLADLENSRDDLLYELHKQPKQHASDKITLKRHFEKVDTVSQELEKKLRLILSRTLNTLRKKPTIIVTALRIIEREEKNDQFALQQQKVTGFLPPGRPKAWRRMIMDVLQQSVITRIEGSKLEERADNKMWLVRDLEILRQIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDNIVRSGLEGNEYVSMMAWVTHTYPGVELMSHPDLNVDVHRQIGTLLRPEHLKALEDEYLQNMQRNFQEWMTKAAETEKQEWFTETVPDQDEEYYHTSAPVIIFQMIDQHLQVTNTIHQELTFKALVMSIQQVEIFGQTYLKNVIELKEHHFRNRDQIKYFTHYIITIVNNSQQMVELAQQMKQLYWPKSRTEHYEDFERLLATFQRIRAHAASYLLEEAFLDMECHFNDLFTAKWLASNIAVDTICVTLDDYFQDYNHLRPNNFEMVINEAQKLLAKRYIRALLSKRLSKPRAECDAITRKIKTEAKRFKLFFEKIAPKISLSDSPLDLISTLSALLSSDIELLVLDLHTLLGSYPSLNEDHLVRLFYIRNDVKAAEVREKVQDAMKSKKAMVSIAKQDCIFKEIVFSDKLW", "length": 738 }, "evidence": [ { "id": "F1NHD9", "url": "https://omabrowser.org/oma/group/F1NHD9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" }, { "name": "exocyst localization", "id": "GO:0051601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051601", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "F1NHD9", "url": "https://www.uniprot.org/uniprotkb/F1NHD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NHD9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 745, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NHD9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NHD9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3X0-1", "uniprot_ac": "E1C3X0", "uniprot_id": "E1C3X0_CHICK", "mass": { "chemical_mass": 17940.0, "monoisotopic_mass": 17940.0 }, "refseq": { "ac": "NP_001239089", "name": "trafficking protein particle complex subunit 6B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239089" }, "gene_names": [ { "name": "TRAPPC6A", "type": "recommended", "evidence": [ { "id": "E1C3X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ] }, { "name": "TRAPPC6A", "type": "synonym", "evidence": [ { "id": "NP_001239089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239089" } ] }, { "name": "TRAPPC6B", "type": "synonym", "evidence": [ { "id": "NP_001239089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239089" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit 6B", "type": "recommended", "evidence": [ { "id": "E1C3X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3X0/entry#names_and_taxonomy" } ] }, { "name": "trafficking protein particle complex 6B", "type": "synonym", "evidence": [ { "id": "NP_001239089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239089" } ] }, { "name": "trafficking protein particle complex subunit 6B", "type": "synonym", "evidence": [ { "id": "NP_001239089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239089" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX932658.1, BX935910.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992415, SAMEA103992437 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BU398441.1, BX935910.2, BX932692.1 and BX275471.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001239089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239089" } ] }, { "annotation": "Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival.", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0#function" }, { "database": "UniProtKB", "id": "ARBA00057720", "url": "https://www.uniprot.org/uniprotkb/ARBA00057720#function" }, { "database": "UniProtKB", "id": "A0A8V0XSI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSI5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRAPPC6A", "url": "https://www.uniprot.org/uniprotkb/E1C3X0", "locus": { "chromosome": "5", "start_pos": 37105592, "end_pos": 37111101, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006363", "url": "https://www.ensembl.org/id/ENSGALG00010006363" } ] } } ], "crossref": [ { "id": "E1C3X0", "url": "https://alphafold.ebi.ac.uk/entry/E1C3X0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010157", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14944", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14944", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423337", "url": "https://www.ncbi.nlm.nih.gov/gene/423337", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423337", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423337", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKEFWTA", "url": "https://omabrowser.org/oma/group/CKEFWTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XSI5", "url": "https://www.orthodb.org/?gene=A0A8V0XSI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3X0", "url": "https://www.orthodb.org/?gene=E1C3X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12817:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12817:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04051", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04051", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001239089", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XSI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XSI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XSI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3X0-1", "url": "https://www.uniprot.org/uniprotkb/E1C3X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADEALFLLLHNEMVAGLYRAAEQGEGENGRCTTKLESMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHAPKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKM", "length": 158, "header": "tr|E1C3X0-1|E1C3X0_CHICK Isoform 1 of Trafficking protein particle complex subunit 6B OS=Gallus gallus OX=9031 GN=TRAPPC6A PE=1 SV=1 CANONICAL=E1C3X0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XSI5-1", "url": "https://www.uniprot.org/uniprotkb/E1C3X0/entry#A0A8V0XSI5-1", "sequence": { "sequence": "MADEALFLLLHNEMVAGLYRAAEQGEGENGRCTTKLESMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHAPKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPASTTHSCNECVQEDD", "length": 162, "header": "tr|A0A8V0XSI5-1|E1C3X0_CHICK Computationally mapped isoform of Trafficking protein particle complex subunit 6B OS=Gallus gallus OX=9031 GN=TRAPPC6A PE=1 SV=1 CANONICAL=E1C3X0-1" }, "locus": { "chromosome": "5", "start_pos": 37110920, "end_pos": 37106969, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015202.1", "url": "https://www.ensembl.org/id/ENSGALT00010015202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008935.1", "url": "https://www.ensembl.org/id/ENSGALP00010008935.1" } ] } }, { "isoform_ac": "E1C3X0-1", "url": "https://www.uniprot.org/uniprotkb/E1C3X0/entry#E1C3X0-1", "sequence": { "sequence": "MADEALFLLLHNEMVAGLYRAAEQGEGENGRCTTKLESMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHAPKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKM", "length": 158, "header": "tr|E1C3X0-1|E1C3X0_CHICK Isoform 1 of Trafficking protein particle complex subunit 6B OS=Gallus gallus OX=9031 GN=TRAPPC6A PE=1 SV=1 CANONICAL=E1C3X0-1" }, "locus": { "chromosome": "5", "start_pos": 37110920, "end_pos": 37107692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015203.1", "url": "https://www.ensembl.org/id/ENSGALT00010015203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008936.1", "url": "https://www.ensembl.org/id/ENSGALP00010008936.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423337", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423337", "resource": "KEGG Pathway" }, { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SV82-1", "protein_name": "Trafficking protein particle complex subunit 6B", "gene_name": "TRAPPC6B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL", "length": 130 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MCS4-1", "protein_name": "Trafficking protein particle complex subunit 6B", "gene_name": "Trappc6b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQLSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL", "length": 158 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZES2-1", "protein_name": "Trafficking protein particle complex subunit 6B", "gene_name": "Trappc6b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLIQLSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL", "length": 158 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32L78-1", "protein_name": "Trafficking protein particle complex subunit 6B", "gene_name": "TRAPPC6B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL", "length": 158 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86SZ2-1", "protein_name": "Trafficking protein particle complex subunit 6B", "gene_name": "TRAPPC6B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL", "length": 158 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CAW4-1", "protein_name": "Transport protein particle (TRAPP) component", "gene_name": "TRAPPC6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGREVAESCVDTMLMEMVAMYSGRFYANKPELAARRIEAIGYQVGHQLSERYTMERPRFSDHLEAIKFICKDFWSEVFKKQIDNLKTNHRGTFVLQDNKFRWLSRVSIDPSSENETQDPSTPGESKAAQAVSMYLYFPCGIIRGVLSNLGIPCAVSADISSLPTCSFVIRVKA", "length": 173 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D289-1", "protein_name": "Trafficking protein particle complex subunit 6B", "gene_name": "Trappc6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADEALFLLLHNEMVSGVYKSAEQGEVENGRCVTKLESMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLIQLSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL", "length": 158 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VF82-1", "protein_name": "Trafficking protein particle complex subunit 6B", "gene_name": "Trs33", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSEEILFDCLHAEIVNYCLDSNKEHDLATLEYIGFTTGYRLIERLTREVSRFKDELETMKFICTDFWMLIYKKQVDNLRTNNHGMYVVQDKAFRFLTRISPGTKQLEHAPKFVAFTCGLVRGALSNLGINSTVTAEVQSIPACKFHIEVNRN", "length": 152 }, "evidence": [ { "id": "E1C3X0", "url": "https://omabrowser.org/oma/group/E1C3X0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" }, { "name": "cis-Golgi network", "id": "GO:0005801", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005801", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" }, { "name": "TRAPP complex", "id": "GO:0030008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030008", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "E1C3X0", "url": "https://www.uniprot.org/uniprotkb/E1C3X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C6V5-1", "uniprot_ac": "E1C6V5", "uniprot_id": "E1C6V5_CHICK", "mass": { "chemical_mass": 41367.0, "monoisotopic_mass": 41367.0 }, "refseq": { "ac": "XP_004935480", "name": "fasciculation and elongation protein zeta-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935480" }, "gene_names": [ { "name": "FEZ2", "type": "recommended", "evidence": [ { "id": "E1C6V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6V5" } ] }, { "name": "FEZ2", "type": "synonym", "evidence": [ { "id": "XP_004935480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935480" } ] } ], "protein_names": [ { "name": "Fasciculation and elongation protein zeta 2", "type": "synonym", "evidence": [ { "id": "E1C6V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6V5/entry#names_and_taxonomy" } ] }, { "name": "fasciculation and elongation protein zeta-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004935480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935480" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004935480.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004935480", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935480" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6V5", "url": "https://www.uniprot.org/uniprotkb/E1C6V5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FEZ2", "url": "https://www.uniprot.org/uniprotkb/E1C6V5", "locus": { "chromosome": "3", "start_pos": 31923960, "end_pos": 31952289, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007551", "url": "https://www.ensembl.org/id/ENSGALG00010007551" } ] } } ], "crossref": [ { "id": "E1C6V5", "url": "https://alphafold.ebi.ac.uk/entry/E1C6V5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010594", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421472", "url": "https://www.ncbi.nlm.nih.gov/gene/421472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421472", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFRDYGT", "url": "https://omabrowser.org/oma/group/CFRDYGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XT85", "url": "https://www.orthodb.org/?gene=A0A8V0XT85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C6V5", "url": "https://www.orthodb.org/?gene=E1C6V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12394:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12394:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004935480", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004935480", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XT85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XT85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6V5", "url": "https://www.uniprot.org/uniprotkb/E1C6V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6V5-1", "url": "https://www.uniprot.org/uniprotkb/E1C6V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAASQRDPGDWQDFSGFQPSAGSAPEAARGDKGGWDLGAKLSLCFEPPPARAAGCGESRVPLRPLTEQSALQDDEIWNALTDNYGNVMPVDWKSSHTRALHLPTLNLSEKGVNDNLNLDLSDDEELREQLDMHSIIVSCINDEPLFTAEQVIEEIEEMMQESPDPEDDETPTQSDRLSILSQEIQTLKRSSTNNSYEERVKRLSVAELNELLEEIETAIKDYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQREHKETAKKKKKLKNGSPQNGKQERGHMPGTRFSMEGISNVIQNGFRHTFGNSGGEKQYLTTVIPYEKKNGPPSVEDLQTLTKILHAMKEDSEKVPSLLTDYILKVLCPT", "length": 369, "header": "tr|E1C6V5-1|E1C6V5_CHICK Isoform 1 of Fasciculation and elongation protein zeta 2 OS=Gallus gallus OX=9031 GN=FEZ2 PE=3 SV=4 CANONICAL=E1C6V5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XT85-1", "url": "https://www.uniprot.org/uniprotkb/E1C6V5/entry#A0A8V0XT85-1", "sequence": { "sequence": "MAAAASQRDPGDWQDFSGFQPSAGSAPEAARGDKGGWDLGAKLSLCFEPPPARAAGCGESRVPLRPLTEQSALQDDEIWNALTDNYGNVMPVDWKSSHTRALHLPTLNLSEKGVNDNLNLDLSDDEELREQLDMHSIIVSCINDEPLFTAEQVIEEIEEMMQESPDPEDDETPTQSDRLSILSQEIQTLKRSSTNNSYEERVKRLSVAELNELLEEIETAIKDYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQREHKETAKKKKKLKNGSPQNGKQERGHMPGTRFSMEGISNVIQNGFRHTFGNSGGEKQYLTTVIPYEKKNGPPSVEDLQTLTKILHAMKEDSEKVPSLLTDYILKALV", "length": 367, "header": "tr|A0A8V0XT85-1|E1C6V5_CHICK Computationally mapped isoform of Fasciculation and elongation protein zeta 2 OS=Gallus gallus OX=9031 GN=FEZ2 PE=3 SV=1 CANONICAL=E1C6V5-1" }, "locus": { "chromosome": "3", "start_pos": 31952199, "end_pos": 31928205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017979.1", "url": "https://www.ensembl.org/id/ENSGALT00010017979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009898.1", "url": "https://www.ensembl.org/id/ENSGALP00010009898.1" } ] } }, { "isoform_ac": "E1C6V5-1", "url": "https://www.uniprot.org/uniprotkb/E1C6V5/entry#E1C6V5-1", "sequence": { "sequence": "MAAAASQRDPGDWQDFSGFQPSAGSAPEAARGDKGGWDLGAKLSLCFEPPPARAAGCGESRVPLRPLTEQSALQDDEIWNALTDNYGNVMPVDWKSSHTRALHLPTLNLSEKGVNDNLNLDLSDDEELREQLDMHSIIVSCINDEPLFTAEQVIEEIEEMMQESPDPEDDETPTQSDRLSILSQEIQTLKRSSTNNSYEERVKRLSVAELNELLEEIETAIKDYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQREHKETAKKKKKLKNGSPQNGKQERGHMPGTRFSMEGISNVIQNGFRHTFGNSGGEKQYLTTVIPYEKKNGPPSVEDLQTLTKILHAMKEDSEKVPSLLTDYILKVLCPT", "length": 369, "header": "tr|E1C6V5-1|E1C6V5_CHICK Isoform 1 of Fasciculation and elongation protein zeta 2 OS=Gallus gallus OX=9031 GN=FEZ2 PE=3 SV=4 CANONICAL=E1C6V5-1" }, "locus": { "chromosome": "3", "start_pos": 31952199, "end_pos": 31927727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010017985.1", "url": "https://www.ensembl.org/id/ENSGALT00010017985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009901.1", "url": "https://www.ensembl.org/id/ENSGALP00010009901.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421472", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LA60-1", "protein_name": "Fasciculation and elongation protein zeta 2", "gene_name": "FEZ2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAADGDWQDFYEFQEPARSLQDQENCNASPDSGAGPDGGGDGFRALACSLEEKLSLCFRPLGPGAEPPRAAVRPITECSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGVSDGLLFDTSDDEELREQLDMHSIIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSTSSYEERVKRLSVSELNELLEEVETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHKETAKKKKKLKNGSSQNGKNERSHMPGTRFSMEGISNVIQNGLRHTFGNSGGEKQYLTTVIPYEKKNGPPSVEDLQVLTKILRAMKEDSEKVPSLLTDYILKVLCPT", "length": 376 }, "evidence": [ { "id": "E1C6V5", "url": "https://omabrowser.org/oma/group/E1C6V5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6TYB5-1", "protein_name": "Fasciculation and elongation protein zeta-2", "gene_name": "Fez2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADGDWQDFYEFQEPAGSVQEQENCNASPEAGAGAHAGGDSFPALASSLEEKLSLCFRPTSEAEPPRAAVRPITECSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGMNDGLLFDASDEEELREQLDMHSIIVSCVNEEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSMSSYEERVKRLSVSELNELLEEIEAAIKQYSEELVQQLALRDELEFEKEVENSFISALIEVQNKQKEHKETAKKKKKLKSGSSQNGRSERSHMPGTYLTTVIPYEKKSGPPSVEDLQILTKILHAMKEDSEKVPSLLTDYILKVLCPT", "length": 348 }, "evidence": [ { "id": "E1C6V5", "url": "https://omabrowser.org/oma/group/E1C6V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W525-1", "protein_name": "Uncoordinated 76, isoform B", "gene_name": "Unc-76", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRDLGTKMAELKFEAPLAKFEETDEWGGCDFISSQNAINDTLNLNLKDSSAGGKPDATKLRLLEDAVRDAHVSKNGGGVVGGGAGSISPNCNTLQGGSLIEIGLSDVGLVPGEGAGVGLDGLEKRSLAVGDHVDNFTETFGGSLEDLVNTFDEKITKCFGNYEENVEELAPVQVRSQEEIMNECQMWWTITGNFGNILPIDWSKSYTRQMHMPTLNLGQNHTKQQQQNRNQQQQLHNQSHQAYPHTNGLGSGSGSGLDAQTPGDEFNDLTSEDEAVANDLDMHALILNGLNGDMDDQPIKTVEEVIKEIDDIMDEAESPLDEPETCDSEVIEKAREVLGAPLYAEKLQYLTTTQLNELYMEMEVLIQELSETLINELALRDELEFEKELKNSFISLLLAVQNKRRQYHVEKKRGKFQGPEPKYLTTVIPYHLENGTPNNQSLQVLIKILKAINEDSPTVPALLTDYILKVLCPT", "length": 474 }, "evidence": [ { "id": "E1C6V5", "url": "https://omabrowser.org/oma/group/E1C6V5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of autophagosome assembly", "id": "GO:1902902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902902", "evidence": [ { "database": "UniProtKB", "id": "E1C6V5", "url": "https://www.uniprot.org/uniprotkb/E1C6V5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C6V5", "url": "https://www.uniprot.org/uniprotkb/E1C6V5" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "E1C6V5", "url": "https://www.uniprot.org/uniprotkb/E1C6V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C6V5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 369, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C6V5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C6V5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 274, "end_pos": 276 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJ25-1", "uniprot_ac": "F1NJ25", "uniprot_id": "F1NJ25_CHICK", "mass": { "chemical_mass": 21246.0, "monoisotopic_mass": 21246.0 }, "refseq": { "ac": "NP_001376375", "name": "COMM domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376375" }, "gene_names": [ { "name": "COMMD3", "type": "recommended", "evidence": [ { "id": "F1NJ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ25" } ] }, { "name": "COMMD3", "type": "synonym", "evidence": [ { "id": "NP_001376375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376375" } ] } ], "protein_names": [ { "name": "COMM domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "F1NJ25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJ25/entry#names_and_taxonomy" } ] }, { "name": "COMM domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001376375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376375" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX932205.1, CR353894.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000036.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376375" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJ25", "url": "https://www.uniprot.org/uniprotkb/F1NJ25" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COMMD3", "url": "https://www.uniprot.org/uniprotkb/F1NJ25", "locus": { "chromosome": "2", "start_pos": 17652824, "end_pos": 17656050, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005853", "url": "https://www.ensembl.org/id/ENSGALG00010005853" } ] } } ], "crossref": [ { "id": "F1NJ25", "url": "https://alphafold.ebi.ac.uk/entry/F1NJ25", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007900", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007900", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04751", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04751", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420507", "url": "https://www.ncbi.nlm.nih.gov/gene/420507", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DWRLDYC", "url": "https://omabrowser.org/oma/group/DWRLDYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTD5", "url": "https://www.orthodb.org/?gene=A0A8V0XTD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJ25", "url": "https://www.orthodb.org/?gene=F1NJ25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31159:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31159:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376375", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376375", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XTD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJ25", "url": "https://www.uniprot.org/uniprotkb/F1NJ25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJ25-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSAYAQGGCRLLGDPRRLSRRAYAALLRAAFRGVLQPRGGVADPELSDVDPAVLKQCHAAAAACILEAGRQRADRAALSACLEECKLDRERIEQFCTEYQKHREALEELLGSIGRAPPHVTDVSWHLAYRIQTHELHRAYQPTYLLTLSTENSDAGSQPDLSFSCTMEQLQDLVGKLKDAAKSLERATQL", "length": 192, "header": "tr|F1NJ25-1|F1NJ25_CHICK Isoform 1 of COMM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=COMMD3 PE=1 SV=3 CANONICAL=F1NJ25-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XTD5-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ25/entry#A0A8V0XTD5-1", "sequence": { "sequence": "MELSAYAQGGCRLLGDPRRLSRRAYAALLRAAFRGVLQPRGGVADPELSDVDPAVLKQCHAAAAACILEAGRQRADRAALSACLEECKLDRERIEQFCTEYQKHREALEELLGSIGRAPPHVTDVSWHLAYRIQTHELHRAYQPTYLLTLSTENSDAGSQPDLSFSCTMEQLQFQRTTLLYSRKTDLVGKLKDAAKSLERATQL", "length": 204, "header": "tr|A0A8V0XTD5-1|F1NJ25_CHICK Computationally mapped isoform of COMM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=COMMD3 PE=1 SV=1 CANONICAL=F1NJ25-1" }, "locus": { "chromosome": "2", "start_pos": 17656013, "end_pos": 17653114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013973.1", "url": "https://www.ensembl.org/id/ENSGALT00010013973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008241.1", "url": "https://www.ensembl.org/id/ENSGALP00010008241.1" } ] } }, { "isoform_ac": "F1NJ25-1", "url": "https://www.uniprot.org/uniprotkb/F1NJ25/entry#F1NJ25-1", "sequence": { "sequence": "MELSAYAQGGCRLLGDPRRLSRRAYAALLRAAFRGVLQPRGGVADPELSDVDPAVLKQCHAAAAACILEAGRQRADRAALSACLEECKLDRERIEQFCTEYQKHREALEELLGSIGRAPPHVTDVSWHLAYRIQTHELHRAYQPTYLLTLSTENSDAGSQPDLSFSCTMEQLQDLVGKLKDAAKSLERATQL", "length": 192, "header": "tr|F1NJ25-1|F1NJ25_CHICK Isoform 1 of COMM domain-containing protein 3 OS=Gallus gallus OX=9031 GN=COMMD3 PE=1 SV=3 CANONICAL=F1NJ25-1" }, "locus": { "chromosome": "2", "start_pos": 17656013, "end_pos": 17653114, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013979.1", "url": "https://www.ensembl.org/id/ENSGALT00010013979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008243.1", "url": "https://www.ensembl.org/id/ENSGALP00010008243.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TSS3-1", "protein_name": "COMM domain-containing protein 3", "gene_name": "COMMD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELSEYVQKGFQMLADPGSFDSNAFTLLLRAAFQSLLDAQADEAVLDHPDLKCIDPVVLKHCHAAAATYILEAGKQRADKSTLSTYLEDCKFDRERIELFCTEYQNNRNSLEILLGSIGRSLPHITDVSWRLEYQIKTSQLHKMYRPAYLVTLNVENTDFPSHPEINFSCNMEQLQDLVGKLKDASKSLERATQL", "length": 195 }, "evidence": [ { "id": "F1NJ25", "url": "https://omabrowser.org/oma/group/F1NJ25/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MUK6-1", "protein_name": "COMM domain-containing protein 3", "gene_name": "COMMD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELSEYVQKGFQMLADPGSFDSNTFTLLLRAAFQSLLDAQADEAVLDHPDLKHIDPVVLKHCHAAAATYILEAGKQRADRSTLSTYLEDCKFDSERIELFWTEYQNNRNSLEILLGSIGRSLPHITDVSWRLEYQIKTNQLDKMYRPAYLVTLNVENTDSRSHPEISFSCNMEQLQDLVGKLKDASKSLERATQL", "length": 195 }, "evidence": [ { "id": "F1NJ25", "url": "https://omabrowser.org/oma/group/F1NJ25/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54QK4-1", "protein_name": "COMM domain-containing protein 3", "gene_name": "commd3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLSEDVLKGIETLSDEKLINDSVFKHIIDTCFLVILKKKTESDLFDNKAVSSVDTIALKQTFSAFIVFILESMKINYDQSSISDLLEEHKLSSSRIDFISNYFKEYRVAIRKHLSVTNFHFPHIIDVNWRLDLFMKSNAVEKLNTPVYLINLTTEQEENVKGKVQFAATLDQLQDLVFKLRDAQKQIERSSIKS", "length": 195 }, "evidence": [ { "id": "F1NJ25", "url": "https://omabrowser.org/oma/group/F1NJ25/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q63829-1", "protein_name": "COMM domain-containing protein 3", "gene_name": "Commd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELSESVQRGIQTLADPGSFDSNAFALLLRAAFQSLLDARADEAALDHPYLKQIDPVVLKHCHAAAATCILEAGKHQVDKSTLSTYLEDCKFDRERIELFCTEYQNNKNSLETLLGSIGRSLPHITDVSWRLEYQIKTNQLHKMYRPGYLVTLNVENNDSQSYPEINFSCNMEQLQDLVGKLKDASKSLERATQL", "length": 195 }, "evidence": [ { "id": "F1NJ25", "url": "https://omabrowser.org/oma/group/F1NJ25/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P9U3-1", "protein_name": "COMM domain-containing protein 3", "gene_name": "Commd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELSEYVQRGIQTLADPGSFDSSAFALLLRAAFQSLLDAQADEAALDHPDLKHIDPVVLKHCHGAAATYILEAGKHRVDKSTLSTYLEDCKFDRERIELFCTEYQNNKNSLEILLGSIGRALPHITDVSWRLEYQIKTNQLHKMCRPGYLVTLNVENADSQSYPEISFSCSMEQLQDLVGKLKDASKSLERATQL", "length": 195 }, "evidence": [ { "id": "F1NJ25", "url": "https://omabrowser.org/oma/group/F1NJ25/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9I7W2-1", "protein_name": "COMM domain-containing protein 3", "gene_name": "Dmel\\CG12106", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDTLPGSSSALSTDDEQTALISPTVVAGLKNLGAIISLPLTKLLIANSLKLTLHPDATIAPVPELYAKNAACAKQSEYAVVTLFALGTKHGWDGLQLRQQLEQLNLDAAAVDELSRVYEDSRKDLILRQLQIGHSFPHITDIQWRIVCDVKSSTSDCSTGAACFHINLGNFRQSSGERVTIVEFVCNAEELQSLINRLKEIERHCQQMAVV", "length": 211 }, "evidence": [ { "id": "F1NJ25", "url": "https://omabrowser.org/oma/group/F1NJ25/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9UBI1-1", "protein_name": "COMM domain-containing protein 3", "gene_name": "COMMD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSESVQKGFQMLADPRSFDSNAFTLLLRAAFQSLLDAQADEAVLDHPDLKHIDPVVLKHCHAAAATYILEAGKHRADKSTLSTYLEDCKFDRERIELFCTEYQNNKNSLEILLGSIGRSLPHITDVSWRLEYQIKTNQLHRMYRPAYLVTLSVQNTDSPSYPEISFSCSMEQLQDLVGKLKDASKSLERATQL", "length": 195 }, "evidence": [ { "id": "F1NJ25", "url": "https://omabrowser.org/oma/group/F1NJ25/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "F1NJ25", "url": "https://www.uniprot.org/uniprotkb/F1NJ25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "F1NJ25", "url": "https://www.uniprot.org/uniprotkb/F1NJ25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C9G1-1", "uniprot_ac": "E1C9G1", "uniprot_id": "E1C9G1_CHICK", "mass": { "chemical_mass": 42446.0, "monoisotopic_mass": 42446.0 }, "refseq": { "ac": "XP_426287", "name": "microfibrillar-associated protein 3-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426287" }, "gene_names": [ { "name": "MFAP3L", "type": "recommended", "evidence": [ { "id": "E1C9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" } ] }, { "name": "MFAP3L", "type": "synonym", "evidence": [ { "id": "XP_426287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426287" } ] } ], "protein_names": [ { "name": "Microfibrillar-associated protein 3-like", "type": "recommended", "evidence": [ { "id": "E1C9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9G1/entry#names_and_taxonomy" } ] }, { "name": "microfibrillar-associated protein 3-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_426287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426287" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426287.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426287" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C9G1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFAP3L", "url": "https://www.uniprot.org/uniprotkb/E1C9G1", "locus": { "chromosome": "4", "start_pos": 24875936, "end_pos": 24861060, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008344", "url": "https://www.ensembl.org/id/ENSGALG00010008344" } ] } } ], "crossref": [ { "id": "E1C9G1", "url": "https://alphafold.ebi.ac.uk/entry/E1C9G1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009667", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009667", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428729", "url": "https://www.ncbi.nlm.nih.gov/gene/428729", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428729", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428729", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVLIDCN", "url": "https://omabrowser.org/oma/group/CVLIDCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTH2", "url": "https://www.orthodb.org/?gene=A0A8V0XTH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C9G1", "url": "https://www.orthodb.org/?gene=E1C9G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14340:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14340:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XTH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C9G1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C9G1-1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNILNRHHFLCFLPTIRLVILLAALTTAEDVTNSTFNRTGTNTGSVPVVISHIDHIIVKEGCSALIDCNVQGSPSPHYRWYNSNGRLLQEEENKAGKWWFLENGLLNITSVSFEDRGKYTCVASNMYGSVNNTVTLRVVFTSGDMGIYYMIVCLVAFTIVMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRQTAEGQETTETDELYTIPNALKRSDSPTADSDASSLHEPPQQIAIKVSVHPLSKKDCMDGQSQESVQLDTKEEDLPQTPALPTEPSPEPSTELSSDDTALANDTCVIYESHV", "length": 380, "header": "tr|E1C9G1-1|E1C9G1_CHICK Isoform 1 of Microfibrillar-associated protein 3-like OS=Gallus gallus OX=9031 GN=MFAP3L PE=4 SV=2 CANONICAL=E1C9G1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XTH2-1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1/entry#A0A8V0XTH2-1", "sequence": { "sequence": "MNILNRHHFLCFLPTIRLVILLAALTTAEDVTNSTFNRTGTNTGSVPVVISHIDHIIVKEGCSALIDCNVQGSPSPHYRWYNSNGRLLQEEENKGKWWFLENGLLNITSVSFEDRGKYTCVASNMYGSVNNTVTLRVVFTSGDMGIYYMIVCLVAFTIVMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRQTAEGQETTETDELYTIPNALKRSDSPTADSDASSLHEPPQQIAIKVSVHPLSKKDCMDGQSQESVQLDTKEEDLPQTPALPTEPSPEPSTELSSDDTALANDTCVIYESHV", "length": 379, "header": "tr|A0A8V0XTH2-1|E1C9G1_CHICK Computationally mapped isoform of Microfibrillar-associated protein 3-like OS=Gallus gallus OX=9031 GN=MFAP3L PE=4 SV=1 CANONICAL=E1C9G1-1" }, "locus": { "chromosome": "4", "start_pos": 24874932, "end_pos": 24871136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019966.1", "url": "https://www.ensembl.org/id/ENSGALT00010019966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011514.1", "url": "https://www.ensembl.org/id/ENSGALP00010011514.1" } ] } }, { "isoform_ac": "E1C9G1-1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1/entry#E1C9G1-1", "sequence": { "sequence": "MNILNRHHFLCFLPTIRLVILLAALTTAEDVTNSTFNRTGTNTGSVPVVISHIDHIIVKEGCSALIDCNVQGSPSPHYRWYNSNGRLLQEEENKAGKWWFLENGLLNITSVSFEDRGKYTCVASNMYGSVNNTVTLRVVFTSGDMGIYYMIVCLVAFTIVMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRQTAEGQETTETDELYTIPNALKRSDSPTADSDASSLHEPPQQIAIKVSVHPLSKKDCMDGQSQESVQLDTKEEDLPQTPALPTEPSPEPSTELSSDDTALANDTCVIYESHV", "length": 380, "header": "tr|E1C9G1-1|E1C9G1_CHICK Isoform 1 of Microfibrillar-associated protein 3-like OS=Gallus gallus OX=9031 GN=MFAP3L PE=4 SV=2 CANONICAL=E1C9G1-1" }, "locus": { "chromosome": "4", "start_pos": 24874932, "end_pos": 24871136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019969.1", "url": "https://www.ensembl.org/id/ENSGALT00010019969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011517.1", "url": "https://www.ensembl.org/id/ENSGALP00010011517.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428729", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428729", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BB44-1", "protein_name": "Microfibrillar-associated protein 3-like", "gene_name": "MFAP3L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDGVKRHLPVCFLPPVPLLILVSTLATASSVTSSTLNGTNVAVGLAPVVVARTDHIIVKEGNSALINCSVSGLPEPQFKWYNSAGKLLSENEEDQGGGKWQMHDGLLNITKVSFSDRGRYTCMASNVHGSVNNTVTLRVVFTSGDMGVYYMVVCLVAFAVVLVLNVTRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIVEELMEVVGLDEHGHQNFVRHTPEGQEAAAADGDEVYTIPDADSDASSLHEQPQQIAIEVSVHPPAHREPSDDRAAGALEAGDEEDTEPSAEHSPESAAPSTEVTSAALTSEEPTPVEVPDHVLPPGLLEAAEPARPRDGSTHVVYESHV", "length": 400 }, "evidence": [ { "id": "E1C9G1", "url": "https://omabrowser.org/oma/group/E1C9G1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F6P5-1", "protein_name": "Microfibrillar-associated protein 3-like", "gene_name": "mfap3l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSHCYREPLKMKRVNGYVIIYLASVISFCAAGALNITAVDGEGGENRTEANGAGSIPVVVTKTSQIIAREGNCALIDCNVTGDPFPNVQWFNSHGHLLDTKKSDGKWWILDSGVLNITSITFADRGKYTCVASNSHGTANCTVTLRVVFTNGDMGVYYMVVCLVTFTIIMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSIPLPPLIMNCRTFMEEILEVVGVEEMRHTFVRQAPESLDGHGAVAASNPADVFTILRERERSESPAADSDDASLHEQPQHIAIQVSVHPQLTSPGCCNIEAPPLSEIGSTSPPPLAQLPLVEESVEQENKEESVQEGGATKKTQVIYESHV", "length": 397 }, "evidence": [ { "id": "E1C9G1", "url": "https://omabrowser.org/oma/group/E1C9G1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O75121-1", "protein_name": "Microfibrillar-associated protein 3-like", "gene_name": "MFAP3L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRLKSHLTVCFLPSVPFLILVSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAADRDEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDVEETELSAEHSPETAEPSTDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCIIYESHV", "length": 409 }, "evidence": [ { "id": "E1C9G1", "url": "https://omabrowser.org/oma/group/E1C9G1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AYP2-1", "protein_name": "Microfibrillar-associated protein 3-like", "gene_name": "Mfap3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLKSHLTVCLPPSVPFLILVSTLATAKSVTNSTLNGTDVVLGSVPVIIARTDHIIVKEGNSALINCSAFGIPDLEYKWYNSVGKLLKEMDDEKERGGGKWQMLDGGLLNITKVSFSDRGKYTCVASNIYGTINNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAPDRDEVYTIPNSLKRSESPTADSDASSLHEQPQQIAIKVSVHPQSKKDHVDDQEGENLEVKDEEETEPSEEHSPETAEPSTDITTTELTSEEASPVEAPERELPPAHLETTEPAVTCDRNTCIIYESHV", "length": 409 }, "evidence": [ { "id": "E1C9G1", "url": "https://omabrowser.org/oma/group/E1C9G1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D3X9-1", "protein_name": "Microfibrillar-associated protein 3-like", "gene_name": "Mfap3l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLQKSHLTVCLPPSVPFLILVSTLATAKSVTNSTLNGTDVVLGSVPVIIARTDHIIVKEGSSALINCSAYGFPDLEFKWYNSVGKLLKEMDDEKEKGGGKWQMLDGGLLNITKVSFSDRGKYTCVASNIYGTINNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQEAPDRDEVYTIPNSLKRSESPTADSDASSLHEQPQQIAIKVSVHPQSKRDHVDDQEGGHFEVKDEEETEPSEEHSPETAEPSTDITTTELTSEETSPVEAPERGLPPAHLETTEPAVTCDRNTCIIYESHV", "length": 409 }, "evidence": [ { "id": "E1C9G1", "url": "https://omabrowser.org/oma/group/E1C9G1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C9G1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C9G1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C9G1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1C9G1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "E1C9G1", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C9G1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 380, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C9G1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C9G1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C9G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9G1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 137, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 37, "end_pos": 39 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NMC0-1", "uniprot_ac": "F1NMC0", "uniprot_id": "F1NMC0_CHICK", "mass": { "chemical_mass": 85475.0, "monoisotopic_mass": 85475.0 }, "refseq": { "ac": "XP_003640820", "name": "alpha-catulin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640820" }, "gene_names": [ { "name": "CTNNAL1", "type": "recommended", "evidence": [ { "id": "F1NMC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ] }, { "name": "CTNNAL1", "type": "synonym", "evidence": [ { "id": "XP_003640820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640820" } ] } ], "protein_names": [ { "name": "Alpha-catulin", "type": "recommended", "evidence": [ { "id": "F1NMC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NMC0/entry#names_and_taxonomy" } ] }, { "name": "alpha-catulin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003640820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640820" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003640820", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640820" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CTNNAL1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0", "locus": { "chromosome": "2", "start_pos": 88171800, "end_pos": 88112893, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007651", "url": "https://www.ensembl.org/id/ENSGALG00010007651" } ] } } ], "crossref": [ { "id": "F1NMC0", "url": "https://alphafold.ebi.ac.uk/entry/F1NMC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013207", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013207", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100858912", "url": "https://www.ncbi.nlm.nih.gov/gene/100858912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858912", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQQKMAK", "url": "https://omabrowser.org/oma/group/DQQKMAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TXD3", "url": "https://www.orthodb.org/?gene=A0A3Q2TXD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTJ8", "url": "https://www.orthodb.org/?gene=A0A8V0XTJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVJ4", "url": "https://www.orthodb.org/?gene=A0A8V0XVJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XY88", "url": "https://www.orthodb.org/?gene=A0A8V0XY88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XY93", "url": "https://www.orthodb.org/?gene=A0A8V0XY93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NMC0", "url": "https://www.orthodb.org/?gene=F1NMC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46342:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46342:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003640820", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003640820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXD3", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XY93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XY93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NMC0-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSPCSSSGVSSSSSSGLGADAGLEIRTRSVEQTLVPLVSQITTLINHKDKPKRSDKTLQAIQRVGQAVNLAVGRFVTVGEAIANENHELKEEMSIACIEARRAGETIAQLTDVASLDHPESDSHITIFTDKTGVVKAARLLLSSVTKVLVLADRVVIKQIITSRNKVLATMEQLEKVSSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAASRAVLEKCTMMLLTASKTCLRHPDCESARINKDGVFHRMRLALEQVIEIVTDSRPNGENEVAPISIYTGIKEFKNKVEGLRENLYFLSKENLSTMLEVILEHTEDFTDSAYTSHEHREHILELSKQAKMELEQLVSVWMQAQNQKTKDLMEDLEVAILKTCQCMNELKREVHSAATSLAADLLKYHTDHMILKALKITGVEGNLEAVAEYTCKLSEQKEQLVEMCRLLRHVSGTEPLEITCIHAEDTFQVTGPQIISAAETLALHPSSKIAKENLEVFCEAWESQLSDMSMLLREINDVFEGRRGEKRVYLSLPRPGKHNANLKTLKPVKLDTEEQAKIAKLGLELHLLTSDVDSETEKWEDQENEIVQHGQGMSSMAYSMYLFTRGEGLLKTTQDLFHQAEIFATEGMKLASALQVFSEQVHDDDKPLLMLEAEKLIPICKQLQITAKTSVQGKSATFTKVDACIQKTRNVMTLLCQLLPICSRLMRKNKAGNGYLKPAPPWREGRTRTGTNAHTPERRVEMFGIKSLENHLTKMTFLESK", "length": 763, "header": "tr|F1NMC0-1|F1NMC0_CHICK Isoform 1 of Alpha-catulin OS=Gallus gallus OX=9031 GN=CTNNAL1 PE=1 SV=2 CANONICAL=F1NMC0-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TXD3-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0/entry#A0A3Q2TXD3-1", "sequence": { "sequence": "MATSPCSSSGVSSSSSSGLGADAGLEIRTRSVEQTLVPLVSQITTLINHKDKPKRSDKTLQAIQRVGQAVNLAVGRFVTVGEAIANENHELKEEMSIACIEARRAGETIAQLTDVASLDHPESDSHITIFTDKTGVVKAARLLLSSVTKVLVLADRVVIKQIITSRNKVLATMEQLEKVSSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAASRAVLEKCTMMLLTASKTCLRHPDCESARINKDGVFHRMRLALEQVIEIVTDSRPNGENEVAPISIYTGIKEFKNKVEGLRENLYFLSKENLSTMLEVILEHTEDFTDSAYTSHEHREHILELSKQAKMELEQLVSVWMQAQNQKTKDLMEDLEVAILKTCQCMNELKREVHSAATSLAADLLKYHTDHMILKALKITGVEGNLEAVAEYTCKLSEQKEQLVEMCRLLRHVSGTEPLEITCIHAEDTFQVTGPQIISAAETLALHPSSKIAKENLEVFCEAWESQLSDMSMLLREINDVFEGRRGEKRVYLSLPRPGKHNANLKTLKPVKLDTEEQAKIAKLGLELHLLTSDVDSETEKWEDQENEIVQHGQGMSSMAYSMYLFTRGEGLLKTTQDLFHQAEIFATEGMKLASALQVFSEQVHDDDKPLLMLEAEKLIPICKQLQITAKTSVQGKSATFTKEGQLSSDTSYTIRRNQTQAEHLRAVAWFLSHALARLNGSSRLYRLMHAFRKQGM", "length": 736, "header": "tr|A0A3Q2TXD3-1|A0A3Q2TXD3_CHICK Computationally mapped isoform of Alpha-catulin OS=Gallus gallus OX=9031 GN=CTNNAL1 PE=1 SV=1 CANONICAL=F1NMC0-1" }, "locus": { "chromosome": "2", "start_pos": 88170081, "end_pos": 88112985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018216.1", "url": "https://www.ensembl.org/id/ENSGALT00010018216.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010007.1", "url": "https://www.ensembl.org/id/ENSGALP00010010007.1" } ] } }, { "isoform_ac": "A0A8V0XTJ8-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0/entry#A0A8V0XTJ8-1", "sequence": { "sequence": "MLQITTLINHKDKPKRSDKTLQAIQRVGQAVNLAVGRFVTVGEAIANENHELKEEMSIACIEARRAGETIAQLTDVASLDHPESDSHITIFTDKTGVVKAARLLLSSVTKVLVLADRVVIKQIITSRNKVLATMEQLEKVSSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAASRAVLEKCTMMLLTASKTCLRHPDCESARINKDGVFHRMRLALEQVIEIVTDSRPNGENEVAPISIYTGIKEFKNKVEGLRENLYFLSKENLSTMLEVILEHTEDFTDSAYTSHEHREHILELSKQAKMELEQLVSVWMQAQNQKTKDLMEDLEVAILKTCQCMNELKREVHSAATSLAADLLKYHTDHMILKALKITGVEGNLEAVAEYTCKLSEQKEQLVEMCRLLRHVSGTEPLEITCIHAEDTFQVTGPQIISAAETLALHPSSKIAKENLEVFCEAWESQLSDMSMLLREINDVFEGRRGEKRVYLSLPRPGKHNANLKTLKPVKLDTEEQAKIAKLGLELHLLTSDVDSETEKWEDQENEIVQHGQGMSSMAYSMYLFTRGEGLLKTTQDLFHQAEIFATEGMKLASALQVFSEQVHDDDKPLLMLEAEKLIPICKQLQITAKTSVQGKSATFTKVDACIQKTRNVMTLLCQLLPICSRLMRKNKAGNGYLKPAPPWREGRTRTGTNAHTPERRVEMFGIKSLENHLTKMTFLESK", "length": 724, "header": "tr|A0A8V0XTJ8-1|F1NMC0_CHICK Computationally mapped isoform of Alpha-catulin OS=Gallus gallus OX=9031 GN=CTNNAL1 PE=1 SV=1 CANONICAL=F1NMC0-1" }, "locus": { "chromosome": "2", "start_pos": 88170394, "end_pos": 88116911, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018215.1", "url": "https://www.ensembl.org/id/ENSGALT00010018215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010006.1", "url": "https://www.ensembl.org/id/ENSGALP00010010006.1" } ] } }, { "isoform_ac": "A0A8V0XVJ4-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0/entry#A0A8V0XVJ4-1", "sequence": { "sequence": "MATSPCSSSGVSSSSSSGLGADAGLEIRTRSVEQTLVPLVSQITTLINHKDKPKRSDKTLQAIQRVGQAVNLAVGRFVTVGEAIANENHELKEEMSIACIEARRAGETIAQLTDVASLDHPESDSHITIFTDKTGVVKAARLLLSSVTKVLVLADRVVIKQIITSRNKVLATMEQLEKVSSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAASRAVLEKCTMMLLTASKTCLRHPDCESARINKDGVFHRMRLALEQVIEIVTDSRPNGENEVAPISIYTGIKEFKNKVEGLRENLYFLSKENLSTMLEVILEHTEDFTDSAYTSHEHREHILELSKQAKMELEQLVSVWMQAQNQKTKDLMEDLEVAILKTCQCMNELKREVHSAATSLAADLLKYHTDHMILKALKITGVEGNLEAVAEYTCKLSEQKEQLVEMCRLLRHVSGTEPLEITCIHAEDTFQVTGPQIISAAETLALHPSSKIAKENLEVFCEAWESQLSDMSMLLREINDVFEGRRGEKRVYLSLPRPGKHNANLKTLKPVKLDTEEQAKIAKLGLELHLLTSDVDSETEKWEDQENEIVQHGQGMSSMAYSMYLFTRGEGLLKTTQDLFHQAEIFATEGMKLASALQVFSEQVDACIQKTRNVMTLLCQLLPICSRLMRKNKAGNGYLKPAPPWREGRTRTGTNAHTPERRVEMFGIKSLENHLTKMTFLESK", "length": 723, "header": "tr|A0A8V0XVJ4-1|F1NMC0_CHICK Computationally mapped isoform of Alpha-catulin OS=Gallus gallus OX=9031 GN=CTNNAL1 PE=1 SV=1 CANONICAL=F1NMC0-1" }, "locus": { "chromosome": "2", "start_pos": 88170394, "end_pos": 88112985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018223.1", "url": "https://www.ensembl.org/id/ENSGALT00010018223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010014.1", "url": "https://www.ensembl.org/id/ENSGALP00010010014.1" } ] } }, { "isoform_ac": "A0A8V0XY88-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0/entry#A0A8V0XY88-1", "sequence": { "sequence": "MITTLINHKDKPKRSDKTLQAIQRVGQAVNLAVGRFVTVGEAIANENHELKEEMSIACIEARRAGETIAQLTDVASLDHPESDSHITIFTDKTGVVKAARLLLSSVTKVLVLADRVVIKQIITSRNKVLATMEQLEKVSSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAASRAVLEKCTMMLLTASKTCLRHPDCESARINKDGVFHRMRLALEQVIEIVTDSRPNGENEVAPISIYTGIKEFKNKVEGLRENLYFLSKENLSTMLEVILEHTEDFTDSAYTSHEHREHILELSKQAKMELEQLVSVWMQAQNQKTKDLMEDLEVAILKTCQCMNELKREVHSAATSLAADLLKYHTDHMILKALKITGVEGNLEAVAEYTCKLSEQKEQLVEMCRLLRHVSGTEPLEITCIHAEDTFQVTGPQIISAAETLALHPSSKIAKENLEVFCEAWESQLSDMSMLLREINDVFEGRRGEKRVYLSLPRPGKHNANLKTLKPVKLDTEEQAKIAKLGLELHLLTSDVDSETEKWEDQENEIVQHGQGMSSMAYSMYLFTRGEGLLKTTQDLFHQAEIFATEGMKLASALQVFSEQVHDDDKPLLMLEAEKLIPICKQLQITAKTSVQGKSATFTKVDACIQKTRNVMTLLCQLLPICSRLMRKNKAGNGYLKPAPPWREGRTRTGTNAHTPERRVEMFGIKSLENHLTKMTFLESK", "length": 722, "header": "tr|A0A8V0XY88-1|F1NMC0_CHICK Computationally mapped isoform of Alpha-catulin OS=Gallus gallus OX=9031 GN=CTNNAL1 PE=1 SV=1 CANONICAL=F1NMC0-1" }, "locus": { "chromosome": "2", "start_pos": 88170394, "end_pos": 88130189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018212.1", "url": "https://www.ensembl.org/id/ENSGALT00010018212.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010005.1", "url": "https://www.ensembl.org/id/ENSGALP00010010005.1" } ] } }, { "isoform_ac": "A0A8V0XY93-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0/entry#A0A8V0XY93-1", "sequence": { "sequence": "MATSPCSSSGVSSSSSSGLGADAGLEIRTRSVEQTLVPLVSQITTLINHKDKPKRSDKTLQAIQRVGQAVNLAVGRFVTVGEAIANENHELKEEMSIACIEARRAGETIAQLTDVASLDHPESDSHITIFTDKTGVVKAARLLLSSVTKVLVLADRVVIKQIITSRNKVLATMEQLEKVSSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAASRAVLEKCTMMLLTASKTCLRHPDCESARINKDGVFHRMRLALEQVIEIVTDSRPNGENEVAPISIYTGIKEFKQNQKTKDLMEDLEVAILKTCQCMNELKREVHSAATSLAADLLKYHTDHMILKALKITGVEGNLEAVAEYTCKLSEQKEQLVEMCRLLRHVSGTEPLEITCIHAEDTFQVTGPQIISAAETLALHPSSKIAKENLEVFCEAWESQLSDMSMLLREINDVFEGRRGEKRVYLSLPRPGKHNANLKTLKPVKLDTEEQAKIAKLGLELHLLTSDVDSETEKWEDQENEIVQHGQGMSSMAYSMYLFTRGEGLLKTTQDLFHQAEIFATEGMKLASALQVFSEQVHDDDKPLLMLEAEKLIPICKQLQITAKTSVQGKSATFTKVDACIQKTRNVMTLLCQLLPICSRLMRKNKAGNGYLKPAPPWREGRTRTGTNAHTPERRVEMFGIKSLENHLTKMTFLESK", "length": 696, "header": "tr|A0A8V0XY93-1|F1NMC0_CHICK Computationally mapped isoform of Alpha-catulin OS=Gallus gallus OX=9031 GN=CTNNAL1 PE=1 SV=1 CANONICAL=F1NMC0-1" }, "locus": { "chromosome": "2", "start_pos": 88170394, "end_pos": 88112985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018219.1", "url": "https://www.ensembl.org/id/ENSGALT00010018219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010010.1", "url": "https://www.ensembl.org/id/ENSGALP00010010010.1" } ] } }, { "isoform_ac": "F1NMC0-1", "url": "https://www.uniprot.org/uniprotkb/F1NMC0/entry#F1NMC0-1", "sequence": { "sequence": "MATSPCSSSGVSSSSSSGLGADAGLEIRTRSVEQTLVPLVSQITTLINHKDKPKRSDKTLQAIQRVGQAVNLAVGRFVTVGEAIANENHELKEEMSIACIEARRAGETIAQLTDVASLDHPESDSHITIFTDKTGVVKAARLLLSSVTKVLVLADRVVIKQIITSRNKVLATMEQLEKVSSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAASRAVLEKCTMMLLTASKTCLRHPDCESARINKDGVFHRMRLALEQVIEIVTDSRPNGENEVAPISIYTGIKEFKNKVEGLRENLYFLSKENLSTMLEVILEHTEDFTDSAYTSHEHREHILELSKQAKMELEQLVSVWMQAQNQKTKDLMEDLEVAILKTCQCMNELKREVHSAATSLAADLLKYHTDHMILKALKITGVEGNLEAVAEYTCKLSEQKEQLVEMCRLLRHVSGTEPLEITCIHAEDTFQVTGPQIISAAETLALHPSSKIAKENLEVFCEAWESQLSDMSMLLREINDVFEGRRGEKRVYLSLPRPGKHNANLKTLKPVKLDTEEQAKIAKLGLELHLLTSDVDSETEKWEDQENEIVQHGQGMSSMAYSMYLFTRGEGLLKTTQDLFHQAEIFATEGMKLASALQVFSEQVHDDDKPLLMLEAEKLIPICKQLQITAKTSVQGKSATFTKVDACIQKTRNVMTLLCQLLPICSRLMRKNKAGNGYLKPAPPWREGRTRTGTNAHTPERRVEMFGIKSLENHLTKMTFLESK", "length": 763, "header": "tr|F1NMC0-1|F1NMC0_CHICK Isoform 1 of Alpha-catulin OS=Gallus gallus OX=9031 GN=CTNNAL1 PE=1 SV=2 CANONICAL=F1NMC0-1" }, "locus": { "chromosome": "2", "start_pos": 88170394, "end_pos": 88112985, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018229.1", "url": "https://www.ensembl.org/id/ENSGALT00010018229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010020.1", "url": "https://www.ensembl.org/id/ENSGALP00010010020.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100858912", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858912", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0C4DHD7-1", "protein_name": "Alpha-catenin related, isoform C", "gene_name": "alpha-Catr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYGITQSTVNNQRFRVRDMDNEQIMSTFGNIGHLLNIAVERFITIGEIIAEENIDIKGDMYEAAKEARDAGKSIERLCDISPLSGMELRHHIEPLKDYGAIILAARSLLSSVTRILLLVDIIVVKKLLTAKKRASESLEKLESVMNFTEFVRAFSVFGTEMIELAYLTGHHRNSFKEERRRAQMFSARQILEKSIAILLTSSKNSLIHSDCVIVKENRDTVFCQIRRAMDLIHFVVKDSIFDTAKHMPFEKQASNPNYENESIYTTIKRIVNLIKRYKYQMSYYEGSGEGNNNSDAYFSFLDDDLWKSEKNLPSAAGGGRMVNNTNFRKHLSSESLDLREELSLAFEKLFEKAHDFTDSPYISHNHRKNILSYCDNCKLEFDLYLNTIMKDQHEGGGGAGGVGGVGGGQVKGRSDPELGMLSSLEELCKQLVVSVSSQIEDFNESLKICSKLVKSFHVLATNYDIDNLNQRSSKFHDCCDHIFDICKLLQHIAPTERLQVQAKCLAINLRIYGPQVFIAAKILWKYSNSSAANENFESFSDMWKWLTNEISMIAKKILVSINTTKGDRDADAEKCESSSDKLTKSGVPATEDGEMVEYSGLEGKNNGDLNTYQSKWSEDLSDDNDILKRAKNMSAMAFLMYQFTKGNGSLRTTQDLFTQAEYFAEEANRLYKVLRHFSYQVPASDNKKDLLNILDRVPTFVQALQFTVKDHTVGKAATFVKVDHVIRETKNLMNVINKVVSKCFECATKYKLNLTGITGGLTSERSNENMAGGMCDSKGTTSSSDIPXHYGMARRAKGDARRTRVSFLLF", "length": 810 }, "evidence": [ { "id": "F1NMC0", "url": "https://omabrowser.org/oma/group/F1NMC0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A287BNX8-1", "protein_name": "Transmembrane protein 245", "gene_name": "TMEM245", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPRIARPPSLPELPPGFPVPPLGGCRGTMADDGGGPDEAPSPRGSPGRAPRVQRAVGPGSGGGCGETPRTAALALRFDKPIKQAFYNTGAVLFVCLCCGAAVLVYFILEAFLRPLLWAVLCGTFLHPFKSSLTRLGRHWLQRLHRSHTPIVLAALLLPLCFADYGVEALGEQALRRRRLLLLLGAGGPLLYGLYSLGSYLGVQVLLVHVGVLICRGLDYFSSLWIWTLVVGYVLAVSFKWNASTERYLRAISIPVWIILLFHLASLAGSWRIPVFLVIVFLMSVGTLYEKQNGAESSGAELPGQVISMAASTLATLAISITGYESSTEDQPSTPSAGTETMDRGEPPPTISSSSSPSSPSPTLGRQRPEIGSFLRKKKTSDIYFVSLVWAIIGVQIWLNLWIIQLLPVPIAVWILKKLVIHFGVVNFLEKRCSVWWQVIEHFLKERQEALAPWPIIGLGKFLLKVDSKLWHWLNKKMIIWLEKMLDKIISIFIIFLLVIGTLLLALLLTAKVHQESVHMIEVTSNLINETLANHPEWANWLPEAQVVQRALNSAANNVYQYGREWITHKLHKILGDKVNNTAVIEKQVLELWDRLYHSWFVKNVTHSGRHKGHKMHISRQNSWLGDILDWQDIASFVHENIETFLSILESLWIVMSRNVSLLFTTVTTLLTILFYSGTALLNFVLSLIIFLTTLFYLLSSSDEYYKPVKWVISLTPLSQPGPSSNIIGQSVEEAIRGVFDASLKMAGFYGLYTWLTHTIFGINIVFIPSALAAILGAVPFLGTYWAAVPAVLDLWLTQGLGCKAILLLVFHLLPTYFVDTAIYSDISGGGHPYLTGLAVAGGAYYLGLEGAIIGPILLCILVVASNIYSAMLLSPTNSVPTPNQTPWPAQTQRTFRDISEDLKPSID", "length": 907 }, "evidence": [ { "id": "F1NMC0", "url": "https://omabrowser.org/oma/group/F1NMC0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A739-1", "protein_name": "Alpha-catulin", "gene_name": "Ctnnal1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSTAPGGGGAGAVHSSNASGLAFDSGLEIRTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEISIACIEAKQAGETIASLTDVTKWNHLESDGQVTILTDKTGVVQAARLLLSSVTKVLLLADQVVIKQIVTSRNKVLATMERLERVNSFQEFVQIFSQFGNEMVEFAYLTGDRQNDLKDEKKKARMAVARAVLEKGTMMLLTASKTCLRHPSCESAHKNKEGVFDRMRAALEKVIEIVTDCRLNRDTDSSSVSIFTGIKELKLNMEALRENVYFESKENLSAALEVILERVEDFTDSAYTSHEHRERILELSAQARTEVQQFISVWMQAQSRKTKSAAEELELTVLKVSHSLDELRKELHCTAMQLAADLLKFHADHVVLKALKVTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHVSGTEPLEITCMHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDLATLLREISDVFEGRRGEKYDHLSLPKPMKNNANLKSVKSDKPDSEEQAKIAKLGLKLGLLSSDADCEIEKWEDDDNEIVRHGRNMSRMAYSLYLFTRGEGPLKTSQDLIHFLEVFATEGLKLTSSIQSFSKQLKDDDKLMLLLEINKLIPLCHQLQTITKTSLQSKVFLKVDKCVTKIRSMMTLVVQLLSLCYKLLKKMGNDRWVSATNKDAMDGQT", "length": 731 }, "evidence": [ { "id": "F1NMC0", "url": "https://omabrowser.org/oma/group/F1NMC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88327-1", "protein_name": "Alpha-catulin", "gene_name": "Ctnnal1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASPVPGGGGAGAVHSSNAAGFTFDSGLEIRTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIASLTDVTKRSHLESDGQVTILTDKTGVVQAARLLLSSVTKVLLLADRVVIKQIVTSRNKILATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKKARMAVARAVLEKGTMMLLTASKTCLRHPSCESAHTNKEGVFDRMRVALEKVTEIVTDCRLSGETDSSSVSIFTGIKELKVNIEALRENVCFESKENLSAALEAVLEHVEDFTDSAYTSHEHRERILELSSQARTELQQLLSVWMQTQSRKTKSAAEELELTVLKISHSLDELRRELHCTAMQLAADLLKFHADHVVLKALKVTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQMSDMATLLREISDVFEGRRGERCDHLSLPKPTKNSANLKSLKPDKPDSEEQAKIAKLGLKLGLLSSDADCEIEKWEDEENEIVRHGRNMSRMAYSLYLFTRGEGPLKTSQDLIHFLEVFAAEGLKLTSSVQSFSKQLKDDDKLMLLLEINKLIPLCHQLQTITKTSLQSKVFLKVDKCITKIRSMMTLVVQLLSLCYKLLKKMENNRWGSATNKDTMDGQN", "length": 731 }, "evidence": [ { "id": "F1NMC0", "url": "https://omabrowser.org/oma/group/F1NMC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1LU92-1", "protein_name": "Alpha-catulin", "gene_name": "ctnnal1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSPCGGGNFDCGLEIQTRSVEQTLIPLVSQITTLINHKDKLKKTEKTLRAIQRVGQAVSVAVGRFVAVGEAIAAENEDLKEEMGLACFEARRAGTGIAQLTDVSSLEHCDGDGRSTVFSDRTGMVKAARMLLSSVTKVLVLADCIVIKQIISSRNKVLVTLEQLERVSTFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKRARMAAARAVLEKCTMMLLTASKTCLRHPDCESARINKEAVFQRMRIALEQVIEIVTDTRSSGEAKALPVSIYAGIKDFKVKVEALRDSLYGVSCEAVAAQLEALVEKTEDFTDSAYTRHEQRETIIQLCQITRQETKQLINTWRHAQSLKAKEATDEMELSILKTCQCVSDLRQELHKVAVGRATELLKLHSDHLVLQALKASGGDGNLEAVADYASTLTEHNEQLVETCRLLCHVSGTEPLEITCIHAEETFRVIGPQIISAAQTLALHPTSKIAKENLDVFCEAWESQLCDMAILLKEINDVFEGRRGDKKTYLSLPRPGKHSANLKTVKAAKLDAEEQTTIAKLGLELCLLTSDVDSEVERWDEQDHEMVRLCQIISSMAYSMYLFTRGEGLLKTTSDLFHQAEVLSDQGLQLCPVLQSLSTQLLDEDRMLIISETEKLSSACQQLQACAKTPVQGKSAIFQKVDSSIQNTKGILILVVYLLPICNKLIRKCKSERSCLASPQHWREKQLSAPVSEETLNGKGSNGFGVKSLEQHMANLTFLESK", "length": 754 }, "evidence": [ { "id": "F1NMC0", "url": "https://omabrowser.org/oma/group/F1NMC0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9UBT7-1", "protein_name": "Alpha-catulin", "gene_name": "CTNNAL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNGWVSVTNKDTMDSKT", "length": 734 }, "evidence": [ { "id": "F1NMC0", "url": "https://omabrowser.org/oma/group/F1NMC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "F1NMC0", "url": "https://www.uniprot.org/uniprotkb/F1NMC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NMC0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 763, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NMC0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NMC0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 79 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 312, "end_pos": 314 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIF2-1", "uniprot_ac": "F1NIF2", "uniprot_id": "F1NIF2_CHICK", "mass": { "chemical_mass": 64344.0, "monoisotopic_mass": 64344.0 }, "refseq": { "ac": "XP_015131858", "name": "protein NDNF isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131858" }, "gene_names": [ { "name": "NDNF", "type": "recommended", "evidence": [ { "id": "F1NIF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ] }, { "name": "NDNF", "type": "synonym", "evidence": [ { "id": "XP_015131858", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131858" } ] } ], "protein_names": [ { "name": "Protein NDNF", "type": "recommended", "evidence": [ { "id": "F1NIF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIF2/entry#names_and_taxonomy" } ] }, { "name": "protein NDNF isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015131858", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131858" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131858" } ] }, { "annotation": "Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0XGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY1#function" }, { "database": "UniProtKB", "id": "ARBA00046135", "url": "https://www.uniprot.org/uniprotkb/ARBA00046135#function" }, { "database": "UniProtKB", "id": "A0A8V0XL21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL21#function" }, { "database": "UniProtKB", "id": "A0A8V0XTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTP9#function" }, { "database": "UniProtKB", "id": "A0A8V0XTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTQ5#function" }, { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDNF", "url": "https://www.uniprot.org/uniprotkb/F1NIF2", "locus": { "chromosome": "4", "start_pos": 53721098, "end_pos": 53694796, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005399", "url": "https://www.ensembl.org/id/ENSGALG00010005399" } ] } } ], "crossref": [ { "id": "F1NIF2", "url": "https://alphafold.ebi.ac.uk/entry/F1NIF2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011962", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011962", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422672", "url": "https://www.ncbi.nlm.nih.gov/gene/422672", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422672", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422672", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLFRDTS", "url": "https://omabrowser.org/oma/group/YLFRDTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XGY1", "url": "https://www.orthodb.org/?gene=A0A8V0XGY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XL21", "url": "https://www.orthodb.org/?gene=A0A8V0XL21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTP9", "url": "https://www.orthodb.org/?gene=A0A8V0XTP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTQ5", "url": "https://www.orthodb.org/?gene=A0A8V0XTQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NIF2", "url": "https://www.orthodb.org/?gene=F1NIF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14619:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14619:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015131858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131858", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XGY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XGY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XL21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XL21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XL21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NIF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLHCPLLLLLLPLSSRMQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLAVTVTPCDAPLEWKLSVQELPEEASGEGSGEPEPLEQQKQQITNEEGTELFSYKGNDVEYFVSSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRIDVTSLGRTTVTLAWKPSPTASLLKQPIQYCIVINKEHNFKSLCAVEAKLSSDDAFMMAPKPGLDFSPFDFAHFGFPSDSNAGKERGFLKSPSKFGRQTSSKPRVDLHKVCIGNKNIFTVSDLKPDTQYYFDMFAVNTNTNLSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGAKFLRFAPVSSHQKVTFSVHSCLDAVQIQVRRDGKLLLSQNVEGVRQFQLRGKAKAKYLIRLKGNKKGASMLKILATTRPNKQLFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEEQKKREQNQCLGPDTRKKSEKVLCKYFHSQNIQKAVTTETIRGLQSGKSYLLDVYVIGHGGHSVKYQSKLVKTRKFC", "length": 568, "header": "tr|F1NIF2-1|F1NIF2_CHICK Isoform 1 of Protein NDNF OS=Gallus gallus OX=9031 GN=NDNF PE=4 SV=2 CANONICAL=F1NIF2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XGY1-1", "url": "https://www.uniprot.org/uniprotkb/F1NIF2/entry#A0A8V0XGY1-1", "sequence": { "sequence": "MLRASTRYLMLLLHCPLLLLLLPLSSRMQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLAVTVTPCDAPLEWKLSVQELPEEASGEGSGEPEPLEQQKQQITNEEGTELFSYKGNDVEYFVSSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRIDVTSLGRTTVTLAWKPSPTASLLKQPIQYCIVINKEHNFKSLCAVEAKLSSDDAFMMAPKPGLDFSPFDFAHFGFPSDSNAGKERGFLKSPSKFGRQTSSKPRVDLHKVCIGNKNIFTVSDLKPDTQYYFDMFAVNTNTNLSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGAKFLRFAPVSSHQKVTFSVHSCLDAVQIQVRRDGKLLLSQNVEGVRQFQLRGKAKAKYLIRLKGNKKGASMLKILATTRPNKQLFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEEQKKREQNQCLGPDTRKKSEKVLCKYFHSQNIQKAVTTETIRGLQSGKSYLLDVYVIGHGGHSVKYQSKLVKTRKFC", "length": 577, "header": "tr|A0A8V0XGY1-1|A0A8V0XGY1_CHICK Computationally mapped isoform of Protein NDNF OS=Gallus gallus OX=9031 GN=NDNF PE=4 SV=1 CANONICAL=F1NIF2-1" }, "locus": { "chromosome": "4", "start_pos": 53720425, "end_pos": 53703072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012840.1", "url": "https://www.ensembl.org/id/ENSGALT00010012840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007402.1", "url": "https://www.ensembl.org/id/ENSGALP00010007402.1" } ] } }, { "isoform_ac": "A0A8V0XL21-1", "url": "https://www.uniprot.org/uniprotkb/F1NIF2/entry#A0A8V0XL21-1", "sequence": { "sequence": "MCCSWRQTFLLEGRSRDAACEHQVFVRVETSVTAQTREPLPSETGRGRRMLLLHCPLLLLLLPLSSRMQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLAVTVTPCDAPLEWKLSVQELPEEASGEGSGEPEPLEQQKQQITNEEGTELFSYKGNDVEYFVSSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRIDVTSLGRTTVTLAWKPSPTASLLKQPIQYCIVINKEHNFKSLCAVEAKLSSDDAFMMAPKPGLDFSPFDFAHFGFPSDSNAGKERGFLKSPSKFGRQTSSKPRVDLHKVCIGNKNIFTVSDLKPDTQYYFDMFAVNTNTNLSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGAKFLRFAPVSSHQKVTFSVHSCLDAVQIQVRRDGKLLLSQNVEGVRQFQLRGKAKAKYLIRLKGNKKGASMLKILATTRPNKQLFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEEQKKREQNQCLGPDTRKKSEKVLCKYFHSQNIQKAVTTETIRGLQSGKSYLLDVYVIGHGGHSVKYQSKLVKTRKFC", "length": 617, "header": "tr|A0A8V0XL21-1|A0A8V0XL21_CHICK Computationally mapped isoform of Protein NDNF OS=Gallus gallus OX=9031 GN=NDNF PE=4 SV=1 CANONICAL=F1NIF2-1" }, "locus": { "chromosome": "4", "start_pos": 53720425, "end_pos": 53702809, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012839.1", "url": "https://www.ensembl.org/id/ENSGALT00010012839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007401.1", "url": "https://www.ensembl.org/id/ENSGALP00010007401.1" } ] } }, { "isoform_ac": "A0A8V0XTP9-1", "url": "https://www.uniprot.org/uniprotkb/F1NIF2/entry#A0A8V0XTP9-1", "sequence": { "sequence": "MMLLLHCPLLLLLLPLSSRMQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLAVTVTPCDAPLEWKLSVQELPEEASGEGSGEPEPLEQQKQQITNEEGTELFSYKGNDVEYFVSSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRIDVTSLGRTTVTLAWKPSPTASLLKQPIQYCIVINKEHNFKSLCAVEAKLSSDDAFMMAPKPGLDFSPFDFAHFGFPSDSNAGKERGFLKSPSKFGRQTSSKPRVDLHKVCIGNKNIFTVSDLKPDTQYYFDMFAVNTNTNLSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGAKFLRFAPVSSHQKVTFSVHSCLDAVQIQVRRDGKLLLSQNVEGVRQFQLRGKAKAKYLIRLKGNKKGASMLKILATTRPNKQLFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEEQKKREQNQCLGPDTRKKSEKVLCKYFHSQNIQKAVTTETIRGLQSGKSYLLDVYVIGHGGHSVKYQSKLVKTRKFC", "length": 569, "header": "tr|A0A8V0XTP9-1|F1NIF2_CHICK Computationally mapped isoform of Protein NDNF OS=Gallus gallus OX=9031 GN=NDNF PE=4 SV=1 CANONICAL=F1NIF2-1" }, "locus": { "chromosome": "4", "start_pos": 53720425, "end_pos": 53704663, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012836.1", "url": "https://www.ensembl.org/id/ENSGALT00010012836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007398.1", "url": "https://www.ensembl.org/id/ENSGALP00010007398.1" } ] } }, { "isoform_ac": "A0A8V0XTQ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NIF2/entry#A0A8V0XTQ5-1", "sequence": { "sequence": "MEKVSATLAESTQRNLSMQDQRIDTRLHPGVAVGGKHSSWKEEAGMLRASTRYLMLLLHCPLLLLLLPLSSRMQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLAVTVTPCDAPLEWKLSVQELPEEASGEGSGEPEPLEQQKQQITNEEGTELFSYKGNDVEYFVSSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRIDVTSLGRTTVTLAWKPSPTASLLKQPIQYCIVINKEHNFKSLCAVEAKLSSDDAFMMAPKPGLDFSPFDFAHFGFPSDSNAGKERGFLKSPSKFGRQTSSKPRVDLHKVCIGNKNIFTVSDLKPDTQYYFDMFAVNTNTNLSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGAKFLRFAPVSSHQKVTFSVHSCLDAVQIQVRRDGKLLLSQNVEGVRQFQLRGKAKAKYLIRLKGNKKGASMLKILATTRPNKQLFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEEQKKREQNQCLGPDTRKKSEKVLCKYFHSQNIQKAVTTETIRGLQSGKSYLLDVYVIGHGGHSVKYQSKLVKTRKFC", "length": 622, "header": "tr|A0A8V0XTQ5-1|F1NIF2_CHICK Computationally mapped isoform of Protein NDNF OS=Gallus gallus OX=9031 GN=NDNF PE=4 SV=1 CANONICAL=F1NIF2-1" }, "locus": { "chromosome": "4", "start_pos": 53720425, "end_pos": 53695477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012841.1", "url": "https://www.ensembl.org/id/ENSGALT00010012841.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007403.1", "url": "https://www.ensembl.org/id/ENSGALP00010007403.1" } ] } }, { "isoform_ac": "F1NIF2-1", "url": "https://www.uniprot.org/uniprotkb/F1NIF2/entry#F1NIF2-1", "sequence": { "sequence": "MLLLHCPLLLLLLPLSSRMQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLAVTVTPCDAPLEWKLSVQELPEEASGEGSGEPEPLEQQKQQITNEEGTELFSYKGNDVEYFVSSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRIDVTSLGRTTVTLAWKPSPTASLLKQPIQYCIVINKEHNFKSLCAVEAKLSSDDAFMMAPKPGLDFSPFDFAHFGFPSDSNAGKERGFLKSPSKFGRQTSSKPRVDLHKVCIGNKNIFTVSDLKPDTQYYFDMFAVNTNTNLSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGAKFLRFAPVSSHQKVTFSVHSCLDAVQIQVRRDGKLLLSQNVEGVRQFQLRGKAKAKYLIRLKGNKKGASMLKILATTRPNKQLFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEEQKKREQNQCLGPDTRKKSEKVLCKYFHSQNIQKAVTTETIRGLQSGKSYLLDVYVIGHGGHSVKYQSKLVKTRKFC", "length": 568, "header": "tr|F1NIF2-1|F1NIF2_CHICK Isoform 1 of Protein NDNF OS=Gallus gallus OX=9031 GN=NDNF PE=4 SV=2 CANONICAL=F1NIF2-1" }, "locus": { "chromosome": "4", "start_pos": 53720425, "end_pos": 53717000, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012837.1", "url": "https://www.ensembl.org/id/ENSGALT00010012837.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007399.1", "url": "https://www.ensembl.org/id/ENSGALP00010007399.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 80, "start_aa": "Thr", "end_pos": 80, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr80", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422672", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422672", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480Y2S8-1", "protein_name": "Protein NDNF", "gene_name": "NDNF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVPLHWCMLWLLLPLSSKTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEINSYLFRDTPKRYFFVVEEDNTPLSVTVTPCDAPLEWKLSLQELPEEASGEGSGDLEPLDQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASLLKQPIQYCVVINKEHNFKSLCAVEAKLSADDAFMMAPKPGVDFSPFDFAHFGFPSDNSGKERSFLTKPSPKLGRHAYSRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFVANSNSNTSTAYVGTFARTKEEAKQKTVELKDGKVTDVFVKRKGAKFLRFAPVSSHQKVTFFIHSCLDAVQIQVRRDGKLLLSQNVEGIRQFQLRGKPKAKYLIRLKGNKKGASLLKILATTRPSKQSFPSLPEDTRIKAFDKLRTCSSATVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIKGLQPGKSYLLDVYVIGHGGHSVKYQSKVVKTRKFC", "length": 568 }, "evidence": [ { "id": "F1NIF2", "url": "https://omabrowser.org/oma/group/F1NIF2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LE57-1", "protein_name": "Protein NDNF", "gene_name": "Ndnf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMELLYWCLLCLLLPLTSRTQKLPTRDEELFQMQIRDKALFHDSSVIPDGAEISSYLFRDTPRRYFFMVEEDNTPLSVTVTPCDAPLEWKLSLQELPEESSADGSGDPEPLDQQKQQMTDVEGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPDLPYDPRVDVTSIGRTTVTLAWKQSPTASMLKQPIEYCVVINKEHNFKSLCAAETKMSADDAFMVAPKPGLDFSPFDFAHFGFPTDNLGKDRSFLAKPSPKVGRHVYWRPKVDIKKICIGSKNIFTVSDLKPNTQYYFDVFMVNTNTNMSTAFVGAFARTKEEAKQKTVELKDGRVTDVVVKRKGKKFLRFAPVSSHQKVTLFIHSCMDTVQVQVRRDGKLLLSQNVEGIRQFQLRGKPKGKYLIRLKGNKKGASMLKILATTRPSKHAFPSLPDDTRIKAFDKLRTCSSVTVAWLGTQERRKFCIYRKEVGGNYSEEQKRRERNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIRDLQPGKSYLLDVYVVGHGGHSVKYQSKLVKTRKVC", "length": 569 }, "evidence": [ { "id": "F1NIF2", "url": "https://omabrowser.org/oma/group/F1NIF2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6QPI1-1", "protein_name": "Protein NDNF", "gene_name": "NDNF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVPLHWCMLWLLLPLSSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLSVTVTPCDAPLEWKLSLQELPEEASGEGSGDPEPLDQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASVLKQPIQYCVVVSREHNFKSLCAVEAKLSADDAFMMAPKPGLDFSPFDFAHFGFASENSAKERSFLTKPSPKLGRHAHSRPKADIQKVCIGNKNIFTVSDLKPDTQYYFDVFVANSDSNMSTAYLGTFARTKEEAKQKTVELKDGKVTDVFVKRKGAKFLRFAPVPSHQKVTFFVHSCLDAVQIQVRRDGKLLLSQNVEGIRQFQLRGKPKAKYLIRLKGNKKGASMLKILATTRPSKQSFPSLPEDRRIKAFDKLRTCSSVTVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIKGLQPGKSYLLDVYVTGHGGHSVKYQSKVVKTRKVC", "length": 568 }, "evidence": [ { "id": "F1NIF2", "url": "https://omabrowser.org/oma/group/F1NIF2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HT67-1", "protein_name": "Protein NDNF", "gene_name": "Ndnf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLLHWCLLWLLLPLTSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEMSSYLFKDTPRRYFFMVEEDNTPLSVTVTPCDAPLEWKLSLQELPEEGSADGSGDPEPLDQQKQQVTDVKGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLVWKPSPTASMLKQPIEYCVVINKEHNFKSLCAVETKMSADDTFMMAPKPGLDFSPFDFAHFGFPIDNLGKDRSFLAKPPKVGRHAYWRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFMVNTNSNLSTAYVGTFAKTKEEAKQKIMELKDGRVTDVFVKRRGTKFLRFAPVSTHQKASFFIYSCLDAVQVQVKRDGKLLLSQNVEGIRHFQLRGKPKAKYLIRLRGNRKATSMLKILATTKPNKQAFPSLPEDTRIKAFDKLRTCSSVTVAWVGTQERRKFCIYRKEVDGNYSEDQKRREQNRCLGPDTRKKSEKVLCKYFHSPNRKKAVTTETIKDLQPGKSYLLDVYVVGHGGHSVKYQSKVVKTRKVC", "length": 567 }, "evidence": [ { "id": "F1NIF2", "url": "https://omabrowser.org/oma/group/F1NIF2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8C119-1", "protein_name": "Protein NDNF", "gene_name": "Ndnf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELFYWCLLCLLLPLTSRTQKLPTRDEELFQMQIRDKEFFHDSSVIPDGAEVSSYLFRDTPRRYFFMVEEDNTPLSVTVTPCDAPLEWKLSLQELHEGSSADGSGDPELLDQQKQQMTDVEGTELFSYKGNDVEYFLSSSSPSGLYQLELLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSFGRTTVTLAWKPSPTASILKQPIEYCVVINKEHNFKSLCAAETKMNADDAFMVAPKPGLDFNPFDFAHFGFPTDNLGKDRSLLAKPSPKVGRHVYWRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFMVNTNTNMSTAYVGAFVRTKEEAKQKTVELKDGRVTDVFVKRKGKKFLRFAPVSSHQKVTFFIHSCMDAVQVQVRRDGRLLLSQNVEGIRQFQLRGKPKGKYLIRLKGNRKGASKLKILATTRPSKHAFPSLPEDTRIKAFDKLRTCSSVTVAWLGTQERRKFCIYRKEVDGNYSEDQKRREQNQCLGPDTRKKSEKVLCKYFHSQNLQKAVTTETIRDLQPGKSYLLDVYVVGHGGHSVKYQSKIVKTRKVC", "length": 568 }, "evidence": [ { "id": "F1NIF2", "url": "https://omabrowser.org/oma/group/F1NIF2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB73-1", "protein_name": "Protein NDNF", "gene_name": "NDNF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLLHWCLLWLLFPLSSRTQKLPTRDEELFQMQIRDKAFFHDSSVIPDGAEISSYLFRDTPKRYFFVVEEDNTPLSVTVTPCDAPLEWKLSLQELPEDRSGEGSGDLEPLEQQKQQIINEEGTELFSYKGNDVEYFISSSSPSGLYQLDLLSTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTVTLAWKPSPTASLLKQPIQYCVVINKEHNFKSLCAVEAKLSADDAFMMAPKPGLDFSPFDFAHFGFPSDNSGKERSFQAKPSPKLGRHVYSRPKVDIQKICIGNKNIFTVSDLKPDTQYYFDVFVVNINSNMSTAYVGTFARTKEEAKQKTVELKDGKITDVFVKRKGAKFLRFAPVSSHQKVTFFIHSCLDAVQIQVRRDGKLLLSQNVEGIQQFQLRGKPKAKYLVRLKGNKKGASMLKILATTRPTKQSFPSLPEDTRIKAFDKLRTCSSATVAWLGTQERNKFCIYKKEVDDNYNEDQKKREQNQCLGPDIRKKSEKVLCKYFHSQNLQKAVTTETIKGLQPGKSYLLDVYVIGHGGHSVKYQSKVVKTRKFC", "length": 568 }, "evidence": [ { "id": "F1NIF2", "url": "https://omabrowser.org/oma/group/F1NIF2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "response to ischemia", "id": "GO:0002931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002931", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "positive regulation of neuron projection development", "id": "GO:0010976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010976", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "cellular response to hypoxia", "id": "GO:0071456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071456", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "nitric oxide mediated signal transduction", "id": "GO:0007263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007263", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell apoptotic process", "id": "GO:2000352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000352", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "cellular response to fibroblast growth factor stimulus", "id": "GO:0044344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044344", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "vascular wound healing", "id": "GO:0061042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061042", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" }, { "name": "gonadotrophin-releasing hormone neuronal migration to the hypothalamus", "id": "GO:0021828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021828", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "F1NIF2", "url": "https://www.uniprot.org/uniprotkb/F1NIF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 80, 201 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 322, "end_pos": 324 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NAG8-1", "uniprot_ac": "F1NAG8", "uniprot_id": "F1NAG8_CHICK", "mass": { "chemical_mass": 66195.0, "monoisotopic_mass": 66195.0 }, "refseq": { "ac": "XP_419499", "name": "GTP-binding protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419499" }, "gene_names": [ { "name": "GTPBP2", "type": "recommended", "evidence": [ { "id": "F1NAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" } ] }, { "name": "GTPBP2", "type": "synonym", "evidence": [ { "id": "XP_419499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419499" } ] } ], "protein_names": [ { "name": "GTP-binding protein 2", "type": "recommended", "evidence": [ { "id": "F1NAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAG8/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419499" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419499" } ] }, { "annotation": "Involved in the rescue of ribosome stalling due to the presence of non-functional tRNA. Has very low GTP-binding activity.", "evidence": [ { "database": "UniProtKB", "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8#function" }, { "database": "UniProtKB", "id": "ARBA00094357", "url": "https://www.uniprot.org/uniprotkb/ARBA00094357#function" }, { "database": "UniProtKB", "id": "A0A8V0XTR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTR5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GTPBP2", "url": "https://www.uniprot.org/uniprotkb/F1NAG8", "locus": { "chromosome": "3", "start_pos": 30558302, "end_pos": 30548108, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006983", "url": "https://www.ensembl.org/id/ENSGALG00010006983" } ] } } ], "crossref": [ { "id": "F1NAG8", "url": "https://alphafold.ebi.ac.uk/entry/F1NAG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010315", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010315", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03694", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03694", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03708", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03708", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04165", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04165", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421449", "url": "https://www.ncbi.nlm.nih.gov/gene/421449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421449", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEDICEN", "url": "https://omabrowser.org/oma/group/WEDICEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTR5", "url": "https://www.orthodb.org/?gene=A0A8V0XTR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NAG8", "url": "https://www.orthodb.org/?gene=F1NAG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43721", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43721", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43721:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43721:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XTR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NAG8-1", "url": "https://www.uniprot.org/uniprotkb/F1NAG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSRVSELFGGCCRPTGAAFRGRGGAAPGGGGGGSKAKKKSGRSRGGKANNPPYLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLSEEEMRASLKTLRRMAEKVGADITVLREREVDYDSDVPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLKTTIFGLTSYCPDFAMLVVSANTGIAGTTREHLGLAMALKVPFFIVISKVDLCSKATVERTVKQLERILKQPGCNKLPLLVTSDDDAVTAAQQFAQSPNITPIFTLSSVSGENLDLVKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGEHLVVGPTDDGKFLRLKVCSIQRNRSACRVLRAGQAATLALGPFDRSLLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRKGFQVTVHVGNVRQTAVVEKIHGKDKLRTGEKAVVCFRFIKHPEYLKIGAKLLFREGVTKGIGHVTDLQAITTKENGLEESLGPGQLSF", "length": 605, "header": "tr|F1NAG8-1|F1NAG8_CHICK Isoform 1 of GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=GTPBP2 PE=3 SV=2 CANONICAL=F1NAG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XTR5-1", "url": "https://www.uniprot.org/uniprotkb/F1NAG8/entry#A0A8V0XTR5-1", "sequence": { "sequence": "MDSRVSELFGGCCRPTGAAFRGRGGAAPGGGGGGSKAKKKSGRSRGGKANNPPYLPPELVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLSEEEMRASLKTLRRMAEKVGADITVLREREVDYDSDVPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLKTTIFGLTSYCPDFAMLVVSANTGIAGTTREHLGLAMALKVPFFIVISKVDLCSKATVERTVKQLERILKQPGCNKLPLLVTSDDDAVTAAQQFAQSPNITPIFTLSSVSGENLDLVKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGEHLVVGPTDDGKFLRLKVCSIQRNRSACRVLRAGQAATLALGPFDRSLLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRKGFQVTVHVGNVRQTAVVEKIHGKDKLRTGEKAVVCFRFIKHPEYLKIGAKLLFREGVTKGIGHVTDLQAITTKENGLEESLGPGQLSF", "length": 594, "header": "tr|A0A8V0XTR5-1|F1NAG8_CHICK Computationally mapped isoform of GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=GTPBP2 PE=3 SV=1 CANONICAL=F1NAG8-1" }, "locus": { "chromosome": "3", "start_pos": 30556273, "end_pos": 30548134, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016580.1", "url": "https://www.ensembl.org/id/ENSGALT00010016580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009387.1", "url": "https://www.ensembl.org/id/ENSGALP00010009387.1" } ] } }, { "isoform_ac": "F1NAG8-1", "url": "https://www.uniprot.org/uniprotkb/F1NAG8/entry#F1NAG8-1", "sequence": { "sequence": "MDSRVSELFGGCCRPTGAAFRGRGGAAPGGGGGGSKAKKKSGRSRGGKANNPPYLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLSEEEMRASLKTLRRMAEKVGADITVLREREVDYDSDVPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLKTTIFGLTSYCPDFAMLVVSANTGIAGTTREHLGLAMALKVPFFIVISKVDLCSKATVERTVKQLERILKQPGCNKLPLLVTSDDDAVTAAQQFAQSPNITPIFTLSSVSGENLDLVKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGEHLVVGPTDDGKFLRLKVCSIQRNRSACRVLRAGQAATLALGPFDRSLLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRKGFQVTVHVGNVRQTAVVEKIHGKDKLRTGEKAVVCFRFIKHPEYLKIGAKLLFREGVTKGIGHVTDLQAITTKENGLEESLGPGQLSF", "length": 605, "header": "tr|F1NAG8-1|F1NAG8_CHICK Isoform 1 of GTP-binding protein 2 OS=Gallus gallus OX=9031 GN=GTPBP2 PE=3 SV=2 CANONICAL=F1NAG8-1" }, "locus": { "chromosome": "3", "start_pos": 30556273, "end_pos": 30548134, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010016585.1", "url": "https://www.ensembl.org/id/ENSGALT00010016585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010009389.1", "url": "https://www.ensembl.org/id/ENSGALP00010009389.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 442, "start_aa": "Thr", "end_pos": 442, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr442", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421449", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PAI6-1", "protein_name": "GTP-binding protein 2b", "gene_name": "gtpbp2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVQVANHCSIKSAAKPSSPQKAAESGTETAPKKKSRTRRGKRGKRRRGKKANEPPPFLPPEAEEGNIEYKLKLVNPTQYRFEHLATQLKWRLQEGRGEAVYQIGVEDNGLLVGLTEEDMKASLKTLRRMAEKVGADITLLREREVDCDRARRKIAEVLVRKVPDDQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQTGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHYKYLKTTIFGLTSYCPDFAMLVVGANTGIAGTTREHLGLAMALKVPIFIVVSKVDLCGKSTVEKTVRQLERVLKQPGCNKIPMVVANPDDAVTAAQQFAQSSSVTPIFTLSSVSGENLDLLKVFFNILPPLSNSKEQEELMQQLTEFQVDEIYSVPDVGTVVGGTLYSGVCREGDRLVVGPTDDGKFLRLKVCSIHRNRSGCRVLRAGQAATLALGNFDRSLLRKGMVMVSPKMNPTICWQFEAAIVLLFHAKTFRRGFQVTVHIGNVRQTATVECLLGKEELRTGERAVVCFRFLKHPEYLRVGAKLLFREGVTKGIGHVTHLLPSTQNHVPDQNHNQNHT", "length": 605 }, "evidence": [ { "id": "F1NAG8", "url": "https://omabrowser.org/oma/group/F1NAG8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9BX10-1", "protein_name": "GTP-binding protein 2", "gene_name": "GTPBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSRVSELFGGCCRPGGGPAVGGTLKARGAGSSSGCGGPKGKKKNGRNRGGKANNPPYLPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHRMAEKVGADITVLREREVDYDSDMPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKIDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVTDVQAITAGEAQANMGF", "length": 602 }, "evidence": [ { "id": "F1NAG8", "url": "https://omabrowser.org/oma/group/F1NAG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" } ], "pmid": "" }, { "name": "alpha-aminoacyl-tRNA binding", "id": "GO:1904678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904678", "evidence": [ { "database": "UniProtKB", "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translational elongation", "id": "GO:0006414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006414", "evidence": [ { "database": "UniProtKB", "id": "F1NAG8", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NAG8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 605, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NAG8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NAG8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NAG8" }, { "id": "PS51722", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51722" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tr-type G", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 394, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 442 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 458, "end_pos": 460 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1C9-1", "uniprot_ac": "E1C1C9", "uniprot_id": "E1C1C9_CHICK", "mass": { "chemical_mass": 48392.0, "monoisotopic_mass": 48392.0 }, "refseq": { "ac": "NP_001269164", "name": "BEN domain-containing protein 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269164" }, "gene_names": [ { "name": "BEND7", "type": "recommended", "evidence": [ { "id": "E1C1C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1C9" } ] }, { "name": "BEND7", "type": "synonym", "evidence": [ { "id": "NP_001269164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269164" } ] }, { "name": "C10orf30", "type": "synonym", "evidence": [ { "id": "NP_001269164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269164" } ] } ], "protein_names": [ { "name": "BEN domain containing 7", "type": "synonym", "evidence": [ { "id": "E1C1C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1C9/entry#names_and_taxonomy" } ] }, { "name": "BEN domain-containing protein 7", "type": "synonym", "evidence": [ { "id": "NP_001269164", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269164" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.304317.1, HAEK01077003.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000011.1. On Aug 28, 2013 this sequence version replaced XP_417230.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001269164", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269164" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1C9", "url": "https://www.uniprot.org/uniprotkb/E1C1C9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BEND7", "url": "https://www.uniprot.org/uniprotkb/E1C1C9", "locus": { "chromosome": "1", "start_pos": 7379578, "end_pos": 7427859, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005404", "url": "https://www.ensembl.org/id/ENSGALG00010005404" } ] } } ], "crossref": [ { "id": "E1C1C9", "url": "https://alphafold.ebi.ac.uk/entry/E1C1C9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006682", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006682", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419037", "url": "https://www.ncbi.nlm.nih.gov/gene/419037", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419037", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419037", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAFFNDV", "url": "https://omabrowser.org/oma/group/CAFFNDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XTR7", "url": "https://www.orthodb.org/?gene=A0A8V0XTR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1C9", "url": "https://www.orthodb.org/?gene=E1C1C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35068:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35068:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001269164", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269164", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XTR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XTR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1C9", "url": "https://www.uniprot.org/uniprotkb/E1C1C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1C9-1", "url": "https://www.uniprot.org/uniprotkb/E1C1C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFTERKRSRKSQSFKLINEDYHHEIYKISDYSNDVNGETKETQPISLGDESREIKKQITGMRRLLNDSTGRIYQRVGKEGEKLKEEPQDLDLVWAQRLDPPAESDESLHPCESDAWNELSPQENHFSGQYGTRSKTFQNQTRTMASNGEIPMVNSSIGPNCCTCNCQSTLQAILQELKTMRKLIQIQSAGTQNRQQPPVPLICAQKSTISRKRNKKKKLPLKNVEPFTMNKKTSAAENDKKLSANPESSSLQAVEPSLNVETPLSGFGIILESASSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDQTLANSLPNGKRKRGLNDNRKGLDQNIVGAIKVFTERYCTANHVDKLPGPRDWVQILQDQIKLARRRLKRGSAEATDYDEKPDISLLQAGSLFDTTTDSLIDASLDFPV", "length": 430, "header": "tr|E1C1C9-1|E1C1C9_CHICK Isoform 1 of BEN domain containing 7 OS=Gallus gallus OX=9031 GN=BEND7 PE=4 SV=1 CANONICAL=E1C1C9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XTR7-1", "url": "https://www.uniprot.org/uniprotkb/E1C1C9/entry#A0A8V0XTR7-1", "sequence": { "sequence": "MEFTERKRSRKSQSFKLINEDYHHEIYKISDYSNDVNGETKETQPISLGDESREIKKQITGMRRLLNDSTGRIYQRVGKEGEKLKEEPQDLDLVWAQRLDPPAESDESLHPCESDAWNELSPQENHFSGQYGTRSKTFQNQTRTMASNGEIPMVNSSIGPNCCTCNCQSTLQAILQELKTMRKLIQIQSAGTQNRQQPPVPLICAQKSTISRKRNKKKKLPLKNVEPFTMNKKTSAAENDKKLSANPESSSLQAVEPSLNVETPLSGFGIILESASSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDQTLANSLPNGKRKRGLNDNRKGLDQNIVGAIKVFTERYCTANHVDKLPGPRDWVQILQDQIKLARRRLKRGSAEATDYDEKPDISLLQAG", "length": 411, "header": "tr|A0A8V0XTR7-1|E1C1C9_CHICK Computationally mapped isoform of BEN domain containing 7 OS=Gallus gallus OX=9031 GN=BEND7 PE=4 SV=1 CANONICAL=E1C1C9-1" }, "locus": { "chromosome": "1", "start_pos": 7427692, "end_pos": 7383651, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012851.1", "url": "https://www.ensembl.org/id/ENSGALT00010012851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007413.1", "url": "https://www.ensembl.org/id/ENSGALP00010007413.1" } ] } }, { "isoform_ac": "E1C1C9-1", "url": "https://www.uniprot.org/uniprotkb/E1C1C9/entry#E1C1C9-1", "sequence": { "sequence": "MEFTERKRSRKSQSFKLINEDYHHEIYKISDYSNDVNGETKETQPISLGDESREIKKQITGMRRLLNDSTGRIYQRVGKEGEKLKEEPQDLDLVWAQRLDPPAESDESLHPCESDAWNELSPQENHFSGQYGTRSKTFQNQTRTMASNGEIPMVNSSIGPNCCTCNCQSTLQAILQELKTMRKLIQIQSAGTQNRQQPPVPLICAQKSTISRKRNKKKKLPLKNVEPFTMNKKTSAAENDKKLSANPESSSLQAVEPSLNVETPLSGFGIILESASSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDQTLANSLPNGKRKRGLNDNRKGLDQNIVGAIKVFTERYCTANHVDKLPGPRDWVQILQDQIKLARRRLKRGSAEATDYDEKPDISLLQAGSLFDTTTDSLIDASLDFPV", "length": 430, "header": "tr|E1C1C9-1|E1C1C9_CHICK Isoform 1 of BEN domain containing 7 OS=Gallus gallus OX=9031 GN=BEND7 PE=4 SV=1 CANONICAL=E1C1C9-1" }, "locus": { "chromosome": "1", "start_pos": 7427692, "end_pos": 7381557, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012853.1", "url": "https://www.ensembl.org/id/ENSGALT00010012853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007415.1", "url": "https://www.ensembl.org/id/ENSGALP00010007415.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419037", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419037", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L479-1", "protein_name": "BEN domain containing 7", "gene_name": "Bend7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFSERKRSRKSQSFKLVSRDYHHEVYKISEFSNDVNGETKETQPMFLGDGSMEIKKQITGMRRLLNDRTGRIYQRVGKEGEKLKEEPQDVDLVWPQRLNSSTEAPQGLHPPSRGAWNELPAQSGQFSGQPGPRSRTFQSQPHISASSNGELPGVNSTAGSNCCTCNCQSTLQAILQELKTMRKLMHFQAVGTQNRQQPPISLVCSQRTAISRKRNKKKKVLPKAVEPMTTVKPKPSPSETEKKPAAVAARPPGLQAAECASAEENHILGFGIVLKSPSSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDKTLANSLPNGKRKRGLNDNRKGLDQNIVGAIKDTCTQKKISFRTNCLVFPTSSLLKHQPSCVARAQLSAIFTIKTSAAVEDCLSLYRKLLYCESRGQTSRPTRLGTDSTGPD", "length": 436 }, "evidence": [ { "id": "E1C1C9", "url": "https://omabrowser.org/oma/group/E1C1C9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BSV3-1", "protein_name": "BEN domain-containing protein 7", "gene_name": "Bend7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFSERKRSRKSQSFKLVSRDYHHEVYKISEFSNDVNGETKETQPIYLGDESMEIKKQITGMRRLLNDSTGRIYQRVGKEGEKLKQEPQVVDLVWPQRSNSSTEASQGLHSNSRGAWNELPTQSGQFSGQSGPRSRTFQTQPHISASSNGELPGVNSIVGSNCCTCNCQSTLQAILQELKTMRKLMQFQAVGTQNRQQPPISLMCSQRTAVSRKRNKKKKVLPKTVQPVTAVEPKPSPLETEKKPAASATRPPGLQAAERTSTEENHVLGFGIVLESPSSDPEVQLAEGFDVFMPKSQLDSILSNYTRSGSLLFRKLVCAFFDDKTLANSLPNGKRKRGFNDNRKGLDQNIVGAIKVFTENYCTANHVDKLPGPRDWVQILQDQIKLARRRLKRGSAEVADGDERLDRISLPPTGHTFVIKRETPEDPEPGSVA", "length": 434 }, "evidence": [ { "id": "E1C1C9", "url": "https://omabrowser.org/oma/group/E1C1C9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E1C1C9", "url": "https://www.uniprot.org/uniprotkb/E1C1C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1C9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 430, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1C9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1C9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NLE7-1", "uniprot_ac": "F1NLE7", "uniprot_id": "F1NLE7_CHICK", "mass": { "chemical_mass": 34745.0, "monoisotopic_mass": 34745.0 }, "refseq": { "ac": "XP_420496", "name": "aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420496" }, "gene_names": [ { "name": "AIMP1", "type": "recommended", "evidence": [ { "id": "F1NLE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLE7" } ] }, { "name": "AIMP1", "type": "synonym", "evidence": [ { "id": "XP_420496", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420496" } ] } ], "protein_names": [ { "name": "Aminoacyl tRNA synthetase complex interacting multifunctional protein 1", "type": "synonym", "evidence": [ { "id": "F1NLE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLE7/entry#names_and_taxonomy" } ] }, { "name": "aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_420496", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420496" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_420496.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420496" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NLE7", "url": "https://www.uniprot.org/uniprotkb/F1NLE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AIMP1", "url": "https://www.uniprot.org/uniprotkb/F1NLE7", "locus": { "chromosome": "4", "start_pos": 37971490, "end_pos": 38005571, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010006049", "url": "https://www.ensembl.org/id/ENSGALG00010006049" } ] } } ], "crossref": [ { "id": "F1NLE7", "url": "https://alphafold.ebi.ac.uk/entry/F1NLE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010553", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010553", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02799", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02799", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422533", "url": "https://www.ncbi.nlm.nih.gov/gene/422533", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422533", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422533", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPDLCTN", "url": "https://omabrowser.org/oma/group/QPDLCTN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P0D3", "url": "https://www.orthodb.org/?gene=A0A1D5P0D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XU23", "url": "https://www.orthodb.org/?gene=A0A8V0XU23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XWT3", "url": "https://www.orthodb.org/?gene=A0A8V0XWT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NLE7", "url": "https://www.orthodb.org/?gene=F1NLE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11586", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11586", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11586:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11586:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9856649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_420496", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420496", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P0D3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P0D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XU23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XU23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XWT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XWT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLE7", "url": "https://www.uniprot.org/uniprotkb/F1NLE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NLE7-1", "url": "https://www.uniprot.org/uniprotkb/F1NLE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLARFLMKMAANNAVLNRLEQKGAEADQVIEYLKQQIALLKEKAILQASLREEKKLRVENAKLKKEIEGLKQELIQAEIRNGVKQVAVPSGTTVSTASFSEDVPQPAAVASSGSKDHVKGEDEEKKKKEKVEKKGDKKEKKQQPVAGSSDSKPVDVSRLDLRVGCIITAEKHPDADSLYVEKVDVGEASPRTVVSGLVKYVPLDQMQNRMAVLLCNLKPAKMRGVVSQAMVMCASSPEKVEILAPPVGAVPGDRITFEGFPGDPEKELNPKKKMWEQIQPDLHTNDQCVATYKGVPFEVKGKGVCRAETMANSGIK", "length": 317, "header": "tr|F1NLE7-1|F1NLE7_CHICK Isoform 1 of Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 OS=Gallus gallus OX=9031 GN=AIMP1 PE=1 SV=3 CANONICAL=F1NLE7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P0D3-1", "url": "https://www.uniprot.org/uniprotkb/F1NLE7/entry#A0A1D5P0D3-1", "sequence": { "sequence": "MKMAANNAVLNRLEQKGAEADQVIEYLKQQIALLKEKAILQASLREEKKLRVENAKLKKEIEGLKQELIQAEIRNGVKQVAVPSGTTVSTASFSEDVPQPAAVASSGSKDHVKGEDEEKKKKEKVEKKGDKKEKKQQPVAGSSDSKPVDVSRLDLRVGCIITAEKHPDADSLYVEKVDVGEASPRTVVSGLVKYVPLDQMQNRMAVLLCNLKPAKMRGVVSQAMVMCASSPEKVEILAPPVGAVPGDRITFEGFPGDPEKELNPKKKMWEQIQPDLHTNDQCVATYKGVPFEVKGKGVCRAETMANSGIK", "length": 310, "header": "tr|A0A1D5P0D3-1|A0A1D5P0D3_CHICK Computationally mapped isoform of Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 OS=Gallus gallus OX=9031 GN=AIMP1 PE=1 SV=1 CANONICAL=F1NLE7-1" }, "locus": { "chromosome": "4", "start_pos": 37986922, "end_pos": 37974239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014476.1", "url": "https://www.ensembl.org/id/ENSGALT00010014476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008496.1", "url": "https://www.ensembl.org/id/ENSGALP00010008496.1" } ] } }, { "isoform_ac": "A0A8V0XU23-1", "url": "https://www.uniprot.org/uniprotkb/F1NLE7/entry#A0A8V0XU23-1", "sequence": { "sequence": "MEAFCSKELDTFGVWSSALIAEETRFLARFLMKMAANNAVLNRLEQKGAEADQVIEYLKQQIALLKEKAILQASLREEKKLRVENAKLKKEIEGLKQELIQAEIRNGVKQVAVPSGTTVSTASFSEDVPQPAAVASSGSKDHVKGEDEEKKKKEKVEKKGDKKEKKQQPVAGSSDSKPVDVSRLDLRVGCIITAEKHPDADSLYVEKVDVGEASPRTVVSGLVKYVPLDQMQNRMAVLLCNLKPAKMRGVVSQAMVMCASSPEKVEILAPPVGAVPGDRITFEGFPGDPEKELNPKKKMWEQIQPDLHTNDQCVATYKGVPFEVKGKGVCRAETMANSGIK", "length": 341, "header": "tr|A0A8V0XU23-1|F1NLE7_CHICK Computationally mapped isoform of Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 OS=Gallus gallus OX=9031 GN=AIMP1 PE=1 SV=1 CANONICAL=F1NLE7-1" }, "locus": { "chromosome": "4", "start_pos": 37994871, "end_pos": 37974239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014473.1", "url": "https://www.ensembl.org/id/ENSGALT00010014473.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008494.1", "url": "https://www.ensembl.org/id/ENSGALP00010008494.1" } ] } }, { "isoform_ac": "A0A8V0XWT3-1", "url": "https://www.uniprot.org/uniprotkb/F1NLE7/entry#A0A8V0XWT3-1", "sequence": { "sequence": "TDWSRRVQRLIKLLNTSNSKLLYSKRKLASLREEKKLRVENAKLKKEIEGLKQELIQAEIRNGVKQVAVPSGTTVSTASFSEDVPQPAAVASSGSKDHVKGEDEEKKKKEKVEKKGDKKEKKQQPVAGSSDSKPVDVSRLDLRVGCIITAEKHPDADSLYVEKVDVGEASPRTVVSGLVKYVPLDQMQNRMAVLLCNLKPAKMRGVVSQAMVMCASSPEKVEILAPPVGAVPGDRITFEGFPGDPEKELNPKKKMWEQIQPDLHTNDQCVATYKGVPFEVKGKGVCRAETMANSGIK", "length": 297, "header": "tr|A0A8V0XWT3-1|F1NLE7_CHICK Computationally mapped isoform of Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 OS=Gallus gallus OX=9031 GN=AIMP1 PE=1 SV=1 CANONICAL=F1NLE7-1" }, "locus": { "chromosome": "4", "start_pos": 37986891, "end_pos": 37974239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014478.1", "url": "https://www.ensembl.org/id/ENSGALT00010014478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008497.1", "url": "https://www.ensembl.org/id/ENSGALP00010008497.1" } ] } }, { "isoform_ac": "F1NLE7-1", "url": "https://www.uniprot.org/uniprotkb/F1NLE7/entry#F1NLE7-1", "sequence": { "sequence": "MFLARFLMKMAANNAVLNRLEQKGAEADQVIEYLKQQIALLKEKAILQASLREEKKLRVENAKLKKEIEGLKQELIQAEIRNGVKQVAVPSGTTVSTASFSEDVPQPAAVASSGSKDHVKGEDEEKKKKEKVEKKGDKKEKKQQPVAGSSDSKPVDVSRLDLRVGCIITAEKHPDADSLYVEKVDVGEASPRTVVSGLVKYVPLDQMQNRMAVLLCNLKPAKMRGVVSQAMVMCASSPEKVEILAPPVGAVPGDRITFEGFPGDPEKELNPKKKMWEQIQPDLHTNDQCVATYKGVPFEVKGKGVCRAETMANSGIK", "length": 317, "header": "tr|F1NLE7-1|F1NLE7_CHICK Isoform 1 of Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 OS=Gallus gallus OX=9031 GN=AIMP1 PE=1 SV=3 CANONICAL=F1NLE7-1" }, "locus": { "chromosome": "4", "start_pos": 38005527, "end_pos": 37974239, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010014479.1", "url": "https://www.ensembl.org/id/ENSGALT00010014479.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008498.1", "url": "https://www.ensembl.org/id/ENSGALP00010008498.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422533", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422533", "resource": "KEGG Pathway" }, { "id": "R-GGA-9856649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9856649", "resource": "Reactome", "description": "Transcriptional and post-translational regulation of MITF-M expression and activity" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z7K8-1", "protein_name": "AaRS-interacting multifunctional protein 1", "gene_name": "AIMP1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRRAATTVGSACKNYGQNCSKFARNKRTMADLQQIASNNERAEALINSIEAEISGIQQQLVERQKQELIKENAALAKEVEAALAQLVQLELRNGKKQIPVPGARGFCTSAAPVVMPAEAGPATAAPAAPAPKPAKEPKEKKSKEKKPAAEKPAAAPEAPVDVGRLDLRVGKIVEVGRHPDADSLYLEKIDCGEAAPRTVVSGLVKFVPLEEMQNRLVVVMCNLKPAKMRGVTSEAMVMCASTPEKVEVLSPPAGAVPGDLVHCEGYPRQPDAQLNPKKKIFESCAPDLKTNGELVACYKGAALHVPGKGNVVAQTLKNVNVK", "length": 323 }, "evidence": [ { "id": "F1NLE7", "url": "https://omabrowser.org/oma/group/F1NLE7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P31230-1", "protein_name": "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "gene_name": "Aimp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATNDAVLKRLEQKGAEADQIIEYLKQQVALLKEKAILQATMREEKKLRVENAKLKKEIEELKQELILAEIHNGVEQVRVRLSTPLQTNCTASESVVQSPSVATTASPATKEQIKAGEEKKVKEKTEKKGEKKEKQQSAAASTDSKPIDASRLDLRIGCIVTAKKHPDADSLYVEEVDVGEAAPRTVVSGLVNHVPLEQMQNRMVVLLCNLKPAKMRGVLSQAMVMCASSPEKVEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNAECVATYKGAPFEVKGKGVCRAQTMANSGIK", "length": 310 }, "evidence": [ { "id": "F1NLE7", "url": "https://omabrowser.org/oma/group/F1NLE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q12904-1", "protein_name": "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "gene_name": "AIMP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/F1NLE7" } ], "pmid": "" }, { "name": "aminoacyl-tRNA synthetase multienzyme complex", "id": "GO:0017101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017101", "evidence": [ { "database": "UniProtKB", "id": "F1NLE7", "url": "https://www.uniprot.org/uniprotkb/F1NLE7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NLE7", "url": "https://www.uniprot.org/uniprotkb/F1NLE7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "F1NLE7", "url": "https://www.uniprot.org/uniprotkb/F1NLE7" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell proliferation", "id": "GO:0001937", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001937", "evidence": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NPK3-1", "uniprot_ac": "F1NPK3", "uniprot_id": "F1NPK3_CHICK", "mass": { "chemical_mass": 25020.0, "monoisotopic_mass": 25020.0 }, "refseq": { "ac": "XP_003643058", "name": "peroxiredoxin-like 2C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643058" }, "gene_names": [ { "name": "AAED1", "type": "recommended", "evidence": [ { "id": "F1NPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPK3" } ] }, { "name": "AAED1", "type": "synonym", "evidence": [ { "id": "XP_003643058", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643058" } ] } ], "protein_names": [ { "name": "Peroxiredoxin like 2C", "type": "synonym", "evidence": [ { "id": "F1NPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NPK3/entry#names_and_taxonomy" } ] }, { "name": "peroxiredoxin-like 2C", "type": "synonym", "evidence": [ { "id": "XP_003643058", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643058" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003643058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643058" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NPK3", "url": "https://www.uniprot.org/uniprotkb/F1NPK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AAED1", "url": "https://www.uniprot.org/uniprotkb/F1NPK3", "locus": {} } ], "crossref": [ { "id": "F1NPK3", "url": "https://alphafold.ebi.ac.uk/entry/F1NPK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012624", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012624", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02970", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02970", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427472", "url": "https://www.ncbi.nlm.nih.gov/gene/427472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427472", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MQNTVDH", "url": "https://omabrowser.org/oma/group/MQNTVDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XUS2", "url": "https://www.orthodb.org/?gene=A0A8V0XUS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NPK3", "url": "https://www.orthodb.org/?gene=F1NPK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28630:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28630:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003643058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003643058", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XUS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XUS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPK3", "url": "https://www.uniprot.org/uniprotkb/F1NPK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NPK3-1", "url": "https://www.uniprot.org/uniprotkb/F1NPK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRPPQCPVVQQLRPVSVAPRPELAELREAAYCLVVDADGSRIPFGALYRRQKAIVVFVRNFLCYTCKEYVEDLAKVPRSYLQEANVRLIVIGQSSYHHIKPFCSLTGYTHEMYVDPQREIYKMLGMKRGEGNDVSVQSPHVKSSMLLGSIRSMWRAMTSPAFDFQGDPAQQGGTLILGPGNEVHFLHHDRNRLDHVPINSVLQLAGVKTVNFTNKPQIIDV", "length": 222, "header": "tr|F1NPK3-1|F1NPK3_CHICK Isoform 1 of Peroxiredoxin like 2C OS=Gallus gallus OX=9031 GN=AAED1 PE=4 SV=4 CANONICAL=F1NPK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XUS2-1", "url": "https://www.uniprot.org/uniprotkb/F1NPK3/entry#A0A8V0XUS2-1", "sequence": { "sequence": "MSRPPQCPVVQQLRPVSVAPRPELAELREAAYCLVVDADGSRIPFGALYRRQKAIVVFVRNFLCYTCKEYVEDLAKVPRSYLQEANVRLIVIGQSSYHHIKPFCSLTGYTHEMYVDPQREIYKMLGMKRGEGNDVSGNEVHFLHHDRNRLDHVPINSVLQLAGVKTVNFTNKPQIIDV", "length": 178, "header": "tr|A0A8V0XUS2-1|F1NPK3_CHICK Computationally mapped isoform of Peroxiredoxin like 2C OS=Gallus gallus OX=9031 GN=AAED1 PE=4 SV=1 CANONICAL=F1NPK3-1" }, "locus": { "chromosome": "Z", "start_pos": 42878067, "end_pos": 42874641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020809.1", "url": "https://www.ensembl.org/id/ENSGALT00010020809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011988.1", "url": "https://www.ensembl.org/id/ENSGALP00010011988.1" } ] } }, { "isoform_ac": "F1NPK3-1", "url": "https://www.uniprot.org/uniprotkb/F1NPK3/entry#F1NPK3-1", "sequence": { "sequence": "MSRPPQCPVVQQLRPVSVAPRPELAELREAAYCLVVDADGSRIPFGALYRRQKAIVVFVRNFLCYTCKEYVEDLAKVPRSYLQEANVRLIVIGQSSYHHIKPFCSLTGYTHEMYVDPQREIYKMLGMKRGEGNDVSVQSPHVKSSMLLGSIRSMWRAMTSPAFDFQGDPAQQGGTLILGPGNEVHFLHHDRNRLDHVPINSVLQLAGVKTVNFTNKPQIIDV", "length": 222, "header": "tr|F1NPK3-1|F1NPK3_CHICK Isoform 1 of Peroxiredoxin like 2C OS=Gallus gallus OX=9031 GN=AAED1 PE=4 SV=4 CANONICAL=F1NPK3-1" }, "locus": { "chromosome": "Z", "start_pos": 42878067, "end_pos": 42874641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020798.1", "url": "https://www.ensembl.org/id/ENSGALT00010020798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011985.1", "url": "https://www.ensembl.org/id/ENSGALP00010011985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427472", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A506-1", "protein_name": "Peroxiredoxin like 2C", "gene_name": "Prxl2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPVTRQVSGCAGRVPSPTGSDTERGQPLAAAVAELPVLDASGRRVTFGALFRERRAVVVFVRHFLCYVCKEYVEDLAKIPKSVLQEADVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEEISSSGNNIHFVHRDRNRLDHKPINSVLQLVGVQPVNFLSRPAVIHV", "length": 182 }, "evidence": [ { "id": "F1NPK3", "url": "https://omabrowser.org/oma/group/F1NPK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q148E0-1", "protein_name": "Peroxiredoxin-like 2C", "gene_name": "PRXL2C", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAPSEAPVTRQVSGHAAPAPVPSGPASWQPLAAAVAELPVLDASGRPVLFGELFRERRAIVVFVRHFLCYICKEYVEDLAKIPKSFLQEANVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEEIASSGQSPHVKSNILSGSIRSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFIHHDRNRLDHKPINSVLQLVGVQHVDFTSRPSVIHV", "length": 228 }, "evidence": [ { "id": "F1NPK3", "url": "https://omabrowser.org/oma/group/F1NPK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7RTV5-1", "protein_name": "Peroxiredoxin-like 2C", "gene_name": "PRXL2C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPAPVTRQVSGAAALVPAPSGPDSGQPLAAAVAELPVLDARGQRVPFGALFRERRAVVVFVRHFLCYICKEYVEDLAKIPRSFLQEANVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEEIASSGQSPHIKSNLLSGSLQSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFIHRDRNRLDHKPINSVLQLVGVQHVNFTNRPSVIHV", "length": 226 }, "evidence": [ { "id": "F1NPK3", "url": "https://omabrowser.org/oma/group/F1NPK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D1A0-1", "protein_name": "Peroxiredoxin-like 2C", "gene_name": "Prxl2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPVTRQVSGCAGRVPSPAGSVTERGQPLAAAVAELPVLDASGRRVTFGALFRERRAVVVFVRHFLCYVCKEYVEDLAKIPKSVLREADVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEEISSSGQSPHIKSNLLSGSLQSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFVHRDRNRLDHKPINSVLQLVGVQPVNFMSRPTVIHV", "length": 226 }, "evidence": [ { "id": "F1NPK3", "url": "https://omabrowser.org/oma/group/F1NPK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "F1NPK3", "url": "https://www.uniprot.org/uniprotkb/F1NPK3" } ], "pmid": "" }, { "name": "positive regulation of glycolytic process", "id": "GO:0045821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045821", "evidence": [ { "database": "UniProtKB", "id": "F1NPK3", "url": "https://www.uniprot.org/uniprotkb/F1NPK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NPK3-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 222, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NPK3-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NPK3" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1Y2-1", "uniprot_ac": "E1C1Y2", "uniprot_id": "E1C1Y2_CHICK", "mass": { "chemical_mass": 27042.0, "monoisotopic_mass": 27042.0 }, "refseq": { "ac": "XP_419091", "name": "uncharacterized protein C6orf62 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419091" }, "gene_names": [ { "name": "C6orf62", "type": "recommended", "evidence": [ { "id": "E1C1Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1Y2" } ] }, { "name": "C6orf62", "type": "synonym", "evidence": [ { "id": "XP_419091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419091" } ] } ], "protein_names": [ { "name": "Chromosome 6 open reading frame 62", "type": "synonym", "evidence": [ { "id": "E1C1Y2", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419091" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1Y2", "url": "https://www.uniprot.org/uniprotkb/E1C1Y2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C6orf62", "url": "https://www.uniprot.org/uniprotkb/E1C1Y2", "locus": { "chromosome": "2", "start_pos": 89851890, "end_pos": 89844451, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008027", "url": "https://www.ensembl.org/id/ENSGALG00010008027" } ] } } ], "crossref": [ { "id": "E1C1Y2", "url": "https://alphafold.ebi.ac.uk/entry/E1C1Y2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000013628", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000013628", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421005", "url": "https://www.ncbi.nlm.nih.gov/gene/421005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421005", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421005", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SMFLFVD", "url": "https://omabrowser.org/oma/group/SMFLFVD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XVH3", "url": "https://www.orthodb.org/?gene=A0A8V0XVH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1Y2", "url": "https://www.orthodb.org/?gene=E1C1Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28336:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28336:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XVH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XVH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XVH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1Y2", "url": "https://www.uniprot.org/uniprotkb/E1C1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1Y2-1", "url": "https://www.uniprot.org/uniprotkb/E1C1Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKDKKKKSALFEVSEVIPVMTNNYEENILRGVRDSSYSLESSLELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKGSDEPFRPVQAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPTQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWTVGTIEDHLRPYMPE", "length": 229, "header": "tr|E1C1Y2-1|E1C1Y2_CHICK Isoform 1 of Chromosome 6 open reading frame 62 OS=Gallus gallus OX=9031 GN=C6orf62 PE=4 SV=1 CANONICAL=E1C1Y2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XVH3-1", "url": "https://www.uniprot.org/uniprotkb/E1C1Y2/entry#A0A8V0XVH3-1", "sequence": { "sequence": "MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKDKKKKSALFEVSEVIPVMTNNYEENILRGVRDSSYSLESSLELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKGSDEPFRPAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPTQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWTVGTIEDHLRPYMPE", "length": 227, "header": "tr|A0A8V0XVH3-1|E1C1Y2_CHICK Computationally mapped isoform of Chromosome 6 open reading frame 62 OS=Gallus gallus OX=9031 GN=C6orf62 PE=4 SV=1 CANONICAL=E1C1Y2-1" }, "locus": { "chromosome": "2", "start_pos": 89850710, "end_pos": 89846519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019138.1", "url": "https://www.ensembl.org/id/ENSGALT00010019138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010687.1", "url": "https://www.ensembl.org/id/ENSGALP00010010687.1" } ] } }, { "isoform_ac": "E1C1Y2-1", "url": "https://www.uniprot.org/uniprotkb/E1C1Y2/entry#E1C1Y2-1", "sequence": { "sequence": "MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKDKKKKSALFEVSEVIPVMTNNYEENILRGVRDSSYSLESSLELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKGSDEPFRPVQAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPTQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWTVGTIEDHLRPYMPE", "length": 229, "header": "tr|E1C1Y2-1|E1C1Y2_CHICK Isoform 1 of Chromosome 6 open reading frame 62 OS=Gallus gallus OX=9031 GN=C6orf62 PE=4 SV=1 CANONICAL=E1C1Y2-1" }, "locus": { "chromosome": "2", "start_pos": 89850710, "end_pos": 89846519, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019140.1", "url": "https://www.ensembl.org/id/ENSGALT00010019140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010689.1", "url": "https://www.ensembl.org/id/ENSGALP00010010689.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421005", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421005", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AA29-1", "protein_name": "Chromosome 7 C6orf62 homolog", "gene_name": "C7H6orf62", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKEKKKKSALFEVSEVIPVMTNNYEENILKGVRDSSYSLESSIELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKESDEPFRPVQAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWAVGTIEDHLHPYMPE", "length": 229 }, "evidence": [ { "id": "E1C1Y2", "url": "https://omabrowser.org/oma/group/E1C1Y2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7TP28-1", "protein_name": "Similar to human chromosome 6 open reading frame 62", "gene_name": "C17h6orf62", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKEKKKKSALFEVSEVIPVMTNNYEENILKGVRDSSYSLESSIELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKESDEPFRPVQAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWAVGTIEDHLRPYMPE", "length": 229 }, "evidence": [ { "id": "E1C1Y2", "url": "https://omabrowser.org/oma/group/E1C1Y2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99LU8-1", "protein_name": "Uncharacterized protein C6orf62 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKEKKKKSALFEVSEVIPVMTNNYEENILKGVRDSSYSLESSLELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKESDEPFRPVQAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWAVGTIEDHLRPYMPE", "length": 229 }, "evidence": [ { "id": "E1C1Y2", "url": "https://omabrowser.org/oma/group/E1C1Y2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZU0-1", "protein_name": "Uncharacterized protein C6orf62", "gene_name": "C6orf62", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDPNSRKKQALNRLRAQLRKKKESLADQFDFKMYIAFVFKEKKKKSALFEVSEVIPVMTNNYEENILKGVRDSSYSLESSLELLQKDVVQLHAPRYQSMRRDVIGCTQEMDFILWPRNDIEKIVCLLFSRWKESDEPFRPVQAKFEFHHGDYEKQFLHVLSRKDKTGIVVNNPNQSVFLFIDRQHLQTPKNKATIFKLCSICLYLPQEQLTHWAVGTIEDHLRPYMPE", "length": 229 }, "evidence": [ { "id": "E1C1Y2", "url": "https://omabrowser.org/oma/group/E1C1Y2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1Y2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 229, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1Y2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1Y2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C1Y2", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NC26-1", "uniprot_ac": "F1NC26", "uniprot_id": "F1NC26_CHICK", "mass": { "chemical_mass": 94751.0, "monoisotopic_mass": 94751.0 }, "refseq": { "ac": "NP_001012594", "name": "heat shock 70 kDa protein 4L", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012594" }, "gene_names": [ { "name": "HSPA4L", "type": "recommended", "evidence": [ { "id": "F1NC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ] }, { "name": "HSPA4L", "type": "synonym", "evidence": [ { "id": "NP_001012594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012594" } ] } ], "protein_names": [ { "name": "Heat shock 70 kDa protein 4L", "type": "recommended", "evidence": [ { "id": "F1NC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC26/entry#names_and_taxonomy" } ] }, { "name": "Heat shock 70-related protein APG-1", "type": "synonym", "evidence": [ { "id": "F1NC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC26/entry#names_and_taxonomy" } ] }, { "name": "Osmotic stress protein 94", "type": "synonym", "evidence": [ { "id": "F1NC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC26/entry#names_and_taxonomy" } ] }, { "name": "heat shock 70 kDa protein 4L", "type": "synonym", "evidence": [ { "id": "NP_001012594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012594" } ] }, { "name": "heat shock 70kDa protein 4-like", "type": "synonym", "evidence": [ { "id": "NP_001012594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012594" } ] }, { "name": "heat shock protein apg-1", "type": "synonym", "evidence": [ { "id": "NP_001012594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012594" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ851652.1, SRR13267649.62185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000073.1. On Sep 23, 2021 this sequence version replaced NP_001012594.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001012594", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012594" } ] }, { "annotation": "Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26#function" }, { "database": "UniProtKB", "id": "ARBA00054497", "url": "https://www.uniprot.org/uniprotkb/ARBA00054497#function" }, { "database": "UniProtKB", "id": "A0A8V0XW93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW93#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSPA4L", "url": "https://www.uniprot.org/uniprotkb/F1NC26", "locus": { "chromosome": "4", "start_pos": 33926404, "end_pos": 33877716, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007871", "url": "https://www.ensembl.org/id/ENSGALG00010007871" } ] } } ], "crossref": [ { "id": "F1NC26", "url": "https://alphafold.ebi.ac.uk/entry/F1NC26", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010185", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010185", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11738", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11738", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422496", "url": "https://www.ncbi.nlm.nih.gov/gene/422496", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422496", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422496", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEQSPEI", "url": "https://omabrowser.org/oma/group/WEQSPEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XW93", "url": "https://www.orthodb.org/?gene=A0A8V0XW93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NC26", "url": "https://www.orthodb.org/?gene=F1NC26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45639:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45639:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27508", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001012594", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001012594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XW93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XW93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NC26-1", "url": "https://www.uniprot.org/uniprotkb/F1NC26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVVGIDLGFLNCYIGVARSGGIETIANEYSDRCTPACISLGSKTRAIGNAAKSQIVTNVKNTLHGFKKLHGRAFEDSYIQAERAKLPYELQKMPNGSVGVKVRYLDEERLFAVEQITGMLLAKLKETSESALKKPVADCVISVPSFFTDAERRSVMAAAQIAGLNCLKLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSICAFNKGKLKVLATTFDPFLGGRNFDEALVDYFSEEFRTKYKLNVKENPRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCAALLSRVEPPLRAAMEQAKLQREDIYSIEIVGGATRIPAVKEQISSFFCKEISTTLNADEAVARGCALQCAILSPAFKVREFSITDVVPYSITLRWKSSYEEGTGECEVFSKNHAAPFSKVITFHKKEPFDLEAFYTHPHEVPYPDSRIGRFTIQNVGPQHDGDNSKVKVKVRVNIHGLFSVANASIIEKQNIDGDHNDAAMDTESSSKNQGREDELDKMQVDQDEGVQKSQAEQQSQADEEAENTGIETKASSGDKQDHPTLPRAKTKVKSIDLPIQASLYRQLGQDLINCYIENEGKMMMQDKLEKERNDAKNAVEEYVYDFRDKLCGVFEKFITEEDTNKLTLMLEDTENWLYEDGEDQPKQVYMDKLQELRKFGQPIQERYMEHEERPKVLNELGKKIQLLMKAVEAYKNKDEKYDHLDPAEMEKVEKYISEAMNWLNTKMNAQNKLSLTQDPVVKVAEIISKSKELDSFCNPIIYKPKPKIEPPNDGQSKANGEHNGPVNGQSSTETGPDPAKDNSQQTKPSGEMEVD", "length": 843, "header": "tr|F1NC26-1|F1NC26_CHICK Isoform 1 of Heat shock 70 kDa protein 4L OS=Gallus gallus OX=9031 GN=HSPA4L PE=1 SV=3 CANONICAL=F1NC26-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XW93-1", "url": "https://www.uniprot.org/uniprotkb/F1NC26/entry#A0A8V0XW93-1", "sequence": { "sequence": "MSVVGIDLGFLNCYIGVARSGGIETIANEYSDRCTPACISLGSKTRAIGNAAKSQIVTNVKNTLHGFKKLHGRAFEDSYIQAERAKLPYELQKMPNGSVGVKVRYLDEERLFAVEQITGMLLAKLKETSESALKKPVADCVISVPSFFTDAERRSVMAAAQIAGLNCLKLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSICAFNKGKLKVLATTFDPFLGGRNFDEALVDYFSEEFRTKYKLNVKENPRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCAALLSRVEPPLRAAMEQAKLQREDIYSIEIVGGATRIPAVKEQISSFFCKEISTTLNADEAVARGCALQCAILSPAFKVREFSITDVVPYSITLRWKSSYEEGTGECEVFSKNHAAPFSKVITFHKKEPFDLEAFYTHPHEVPYPDSRIGRFTIQNVGPQHDGDNSKVKVKVRVNIHGLFSVANASIIEKQNIDGDHNDAAMDTESSSKNQGREEDKMQVDQDEGVQKSQAEQQSQADEEAENTGIETKASSGDKQDHPTLPRAKTKVKSIDLPIQASLYRQLGQDLINCYIENEGKMMMQDKLEKERNDAKNAVEEYVYDFRDKLCGVFEKFITEEDTNKLTLMLEDTENWLYEDGEDQPKQVYMDKLQELRKFGQPIQERYMEHEERPKVLNELGKKIQLLMKAVEAYKNKDEKYDHLDPAEMEKVEKYISEAMNWLNTKMNAQNKLSLTQDPVVKVAEIISKSKELDSFCNPIIYKPKPKIEPPNDGQSKANGEHNGPVNGQSSTETGPDPAKDNSQQTKPSGEMEVD", "length": 841, "header": "tr|A0A8V0XW93-1|F1NC26_CHICK Computationally mapped isoform of Heat shock 70 kDa protein 4L OS=Gallus gallus OX=9031 GN=HSPA4L PE=1 SV=1 CANONICAL=F1NC26-1" }, "locus": { "chromosome": "4", "start_pos": 33899788, "end_pos": 33877828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018731.1", "url": "https://www.ensembl.org/id/ENSGALT00010018731.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010281.1", "url": "https://www.ensembl.org/id/ENSGALP00010010281.1" } ] } }, { "isoform_ac": "F1NC26-1", "url": "https://www.uniprot.org/uniprotkb/F1NC26/entry#F1NC26-1", "sequence": { "sequence": "MSVVGIDLGFLNCYIGVARSGGIETIANEYSDRCTPACISLGSKTRAIGNAAKSQIVTNVKNTLHGFKKLHGRAFEDSYIQAERAKLPYELQKMPNGSVGVKVRYLDEERLFAVEQITGMLLAKLKETSESALKKPVADCVISVPSFFTDAERRSVMAAAQIAGLNCLKLMNETTAVALAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSICAFNKGKLKVLATTFDPFLGGRNFDEALVDYFSEEFRTKYKLNVKENPRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCAALLSRVEPPLRAAMEQAKLQREDIYSIEIVGGATRIPAVKEQISSFFCKEISTTLNADEAVARGCALQCAILSPAFKVREFSITDVVPYSITLRWKSSYEEGTGECEVFSKNHAAPFSKVITFHKKEPFDLEAFYTHPHEVPYPDSRIGRFTIQNVGPQHDGDNSKVKVKVRVNIHGLFSVANASIIEKQNIDGDHNDAAMDTESSSKNQGREDELDKMQVDQDEGVQKSQAEQQSQADEEAENTGIETKASSGDKQDHPTLPRAKTKVKSIDLPIQASLYRQLGQDLINCYIENEGKMMMQDKLEKERNDAKNAVEEYVYDFRDKLCGVFEKFITEEDTNKLTLMLEDTENWLYEDGEDQPKQVYMDKLQELRKFGQPIQERYMEHEERPKVLNELGKKIQLLMKAVEAYKNKDEKYDHLDPAEMEKVEKYISEAMNWLNTKMNAQNKLSLTQDPVVKVAEIISKSKELDSFCNPIIYKPKPKIEPPNDGQSKANGEHNGPVNGQSSTETGPDPAKDNSQQTKPSGEMEVD", "length": 843, "header": "tr|F1NC26-1|F1NC26_CHICK Isoform 1 of Heat shock 70 kDa protein 4L OS=Gallus gallus OX=9031 GN=HSPA4L PE=1 SV=3 CANONICAL=F1NC26-1" }, "locus": { "chromosome": "4", "start_pos": 33899788, "end_pos": 33877828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018732.1", "url": "https://www.ensembl.org/id/ENSGALT00010018732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010282.1", "url": "https://www.ensembl.org/id/ENSGALP00010010282.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422496", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422496", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7HDF1-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "Hspa4l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYFAFIIATTAGAIATLAAAAVTAVLIVKGLNTLRDINTDKGTQHADKTSVPSSRIEQEAHKNLDKVDQGLHEEPDTGQQIHEELDPKEVGTKEGPDEKERSSHRDVHGKEQGRQPSSRSAHRGGPQRDAVPAARRGGGMSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERVRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLIAVMDQANLQREDINSIEIVGGATRIPAVKEQVSRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAPMETETSSKNDNKDDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKTKSPPSDKQDRINQTIKKGKVKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAILEDTENWLYEEGEDQPKQVYVDKLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMEKVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNSIVYKPKPKVEVPEDKAKANNEHNGPMDGQSGTETNPDPAKGSSQHAESGEMDVD", "length": 978 }, "evidence": [ { "id": "F1NC26", "url": "https://omabrowser.org/oma/group/F1NC26/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M9MSL3-1", "protein_name": "Heat shock protein 110, isoform G", "gene_name": "Hsp110", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVGGFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSAAAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRNVIFVDFGHSSLQASACAFTKGKLKMLASTWDQIGGRDIDLALGDYFAKEFQERYKINAKTNARANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLAESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFNKPASTTLNQDEAVSRGAALQCAIMSPAVRVREFGVTDIQNYAVKVLWDSEGSAAPGEIEIFPQYHASPFSRLLTINRKGPFNVSIVYGQQVPYPDQTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASEEKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATELPLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAEREKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYEQGPAAFDELKNSIAIARLAVAEFRKGVPKYDHLTETEFINISETADKAQSWLDANLPKFTQSPRTADSPVQISAVRQEVQTLNSCVSSVINRAKPKPTPAKTATPPKDEANAEQNGGEPAANSGDKMDVDNNGQSAAGNDPSMEVE", "length": 836 }, "evidence": [ { "id": "F1NC26", "url": "https://omabrowser.org/oma/group/F1NC26/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P32589-1", "protein_name": "Heat shock protein homolog SSE1", "gene_name": "SSE1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKNRYLGETGKNKQTSNIKNTVANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEPVTKALAQAKLSAEEVDFVEIIGGTTRIPTLKQSISEAFGKPLSTTLNQDEAIAKGAAFICAIHSPTLRVRPFKFEDIHPYSVSYSWDKQVEDEDHMEVFPAGSSFPSTKLITLNRTGDFSMAASYTDITQLPPNTPEQIANWEITGVQLPEGQDSVPVKLKLRCDPSGLHTIEEAYTIEDIEVEEPIPLPEDAPEDAEQEFKKVTKTVKKDDLTIVAHTFGLDAKKLNELIEKENEMLAQDKLVAETEDRKNTLEEYIYTLRGKLEEEYAPFASDAEKTKLQGMLNKAEEWLYDEGFDSIKAKYIAKYEELASLGNIIRGRYLAKEEEKKQAIRSKQEASQMAAMAEKLAAQRKAEAEKKEEKKDTEGDVDMD", "length": 693 }, "evidence": [ { "id": "F1NC26", "url": "https://omabrowser.org/oma/group/F1NC26/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P48722-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "Hspa4l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSTGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSVTLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAAMETEAPKSEGKEDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKAKAPPSDKQDRINQTIKKGKIKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAMLEDTENWLYEEGEDQPKQVYVDRLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMERVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIVYKPKPKVEAPEDKAKTGSEHNGPMDGQSGSETSPDPPKGSSQHTDSGEMEVD", "length": 838 }, "evidence": [ { "id": "F1NC26", "url": "https://omabrowser.org/oma/group/F1NC26/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P83581-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "Hspa4l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSAMLEDTENWLYEELSLTQDPVV", "length": 24 }, "evidence": [ { "id": "F1NC26", "url": "https://omabrowser.org/oma/group/F1NC26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6TMK3-1", "protein_name": "Heat shock protein 88", "gene_name": "hspH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSFVVGFDFGTKNCTIAVAQKGGVDVIANEVSNRLTPSMVSFGEKERYLGESALTNQLRNIRNTITNIKRFIGQEFKTDTVQEELKHEMFQSYEMDNGFVGYNVTYAGEQCSFSSEAILGMLFGKLKKTTEAFVNNPVRDVVISVPVFWNDYQRRAILNAGSIAGLNIIRLINETTATALSYGIYKEWSETDPTNVLFVDVGDSATSVSAVQYKKGQLKVLGTASNPNIGSRVFDETLVKHFAKEFQTKYKINVFENKKALIRLRQACEKVKKILSSNNEAPVSIDSLMDDKDVKGMIDRATFEELANDDMNTIVEPLQRLLSELQMTPDQFQSIEITGGGTRSTSLQKKLSEVLGRDLSKTINSEESVCRGAALQCAMLSPVFRVRPFAVNDVASYPVSVHFKSVSGVEQKLDLFNLKSAIPTPKPLRISFPVTKAEGFEIVVNSTFGTIATVKVDNIPAFTNKSSIKAKVWLDIHGIFHIDEVKLVEQIPEEETAAPAETPAETPANGEAAKPAEEKKVKVKETSLVFTTSRKGLTNELLKAAIEEEGRMQASDLLAIETAEKKNALESYIYDMRSKLQSSLKEYVTPADAETFMTQLNKQMDWLESEEGEDQTKSVYAGKLEELRRLGNPIQKRKQDLEDYPDAVQTLKNIASYVKNEAMIPGERYDHIEKEEKEKLCKDCDDAVEWIDALVAKQQATPKTQPCIINTTEVLAKKTQLEVTAKMILGKPKPKPVEVPKEEPKDTPMESKDAPAEEPVATKDQKMDDILD", "length": 772 }, "evidence": [ { "id": "F1NC26", "url": "https://omabrowser.org/oma/group/F1NC26/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "X1WBR5-1", "protein_name": "Heat shock 70 kDa protein 4L", "gene_name": "hspa4l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVVGIDVGFQNCYIAVARSGGIETIANEYSDRCTPACISLASKNRTIGNAAKSQIITNFKNTVHGFKKFHGRAFDDPFVQGEKSRLPYSLHKLDNGNAGIKVRYLNEDKVFTIEQVTAMLLTKLKETSEHALKKPVVDCVISVPSFFTDVERRSVMDATQIAGLNCLRLINDTTAVALAYGIYKQDLPNPEEKPRNVVFVDIGHSSYQVAIASFNKGKLKMLATAFDPYLGGRNFDEILVEYFCEDFKNRFKLNVKDNPRALLRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVHGKLNRTQFEEMCSQLMMRVEAPLRSVMEQSKLSRDEIYAIEVVGGATRMPAIKERISKFFGKDTSTTLNADEAVARGSALQCAILSPAFKVREFSITDTVPFPITLRWKSPTDESVGECEVYSKNHPAPFSKIITFHKKEPFDLEAFYSCPHDLPYPDVRIGRFSVQNVVPQPDGDSSKVKVKVRVNVHGIFSVSSASLIEKQKGEPEDVQMDTEPTVQNEGRPEEQSKMQVDQEGQGEQPSEEERANNSGIKDGDKQDQGASSSKAKSKVKSVDLPILANTTRQLDRDVLTHFVEYEKKMIIQDKLEKERNDAKNGVEEYVYDLRDKLCGIYEKYVTEDESNRLTIMLEDTENWLYEEGEDQDKEIYQHKLAELKKYGEPIEERYREHEGRPRAFDELGKKLQLFMKVVDMYRDKDERYEHLSAEDMGVVEKSVNEALGWMNTKMNAQSKLSFAQDPAVKVADIIQKIQELEDVCNPILNRPKPKTEELVEEGDKSDGAHNGPTAQQGADSKGNQQTKPPSGEMDVD", "length": 826 }, "evidence": [ { "id": "F1NC26", "url": "https://omabrowser.org/oma/group/F1NC26/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "F1NC26", "url": "https://www.uniprot.org/uniprotkb/F1NC26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NC26-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 843, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NC26-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NC26" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C428-1", "uniprot_ac": "E1C428", "uniprot_id": "E1C428_CHICK", "mass": { "chemical_mass": 51416.0, "monoisotopic_mass": 51416.0 }, "refseq": { "ac": "XP_420452", "name": "SH2 domain-containing protein 4A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420452" }, "gene_names": [ { "name": "SH2D4A", "type": "recommended", "evidence": [ { "id": "E1C428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C428" } ] }, { "name": "SH2D4A", "type": "synonym", "evidence": [ { "id": "XP_420452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420452" } ] } ], "protein_names": [ { "name": "SH2 domain containing 4A", "type": "synonym", "evidence": [ { "id": "E1C428", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C428/entry#names_and_taxonomy" } ] }, { "name": "SH2 domain-containing protein 4A", "type": "synonym", "evidence": [ { "id": "XP_420452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420452" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420452" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C428", "url": "https://www.uniprot.org/uniprotkb/E1C428" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH2D4A", "url": "https://www.uniprot.org/uniprotkb/E1C428", "locus": { "chromosome": "4", "start_pos": 33657215, "end_pos": 33644044, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007762", "url": "https://www.ensembl.org/id/ENSGALG00010007762" } ] } } ], "crossref": [ { "id": "E1C428", "url": "https://alphafold.ebi.ac.uk/entry/E1C428", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010122", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010122", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422487", "url": "https://www.ncbi.nlm.nih.gov/gene/422487", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422487", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NRMKTYG", "url": "https://omabrowser.org/oma/group/NRMKTYG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XYH8", "url": "https://www.orthodb.org/?gene=A0A8V0XYH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C428", "url": "https://www.orthodb.org/?gene=E1C428", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14388:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XYH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XYH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C428", "url": "https://www.uniprot.org/uniprotkb/E1C428", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C428-1", "url": "https://www.uniprot.org/uniprotkb/E1C428-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKQILSEMYIDPDLLAELSEEQKQILFFKMRQEQIRRWKEREAAADKVSAKKPLPKKASTKSVQWKLGADNDVWVWVMGEHPSDKSYAAICEEIQAQRAKRLASEQGKETRETDCAVTQSLQPQPEVLGETEVQGKNKNTVEEQKEEARKNTAGTIGKSQELKKREARDVHQMLADCQMRKGGFSQMKGGHGRNSGEETTVPLKAIPQSHTCSESQKMLQKSDENEPEWQESLRKSKAADEKRRSLARQARDDYRRLSLQGAHRGKQADISKNATAGDRRPLQYPPLPPKPKLLPPAMANGRAVRKEGIQRTISNSAEESIIRWFKEEQFPLRAGYQKTTDTIAPWFHGILTSRKAEELLSKTVPGSFLVRVSEKIKGYVLSYRSAEGCKHFLIDASSDSYSFLGVDQLQHSTLADLVDYHKDEPITSMGKELLLYPCGQEDHEPDYTCLFE", "length": 453, "header": "tr|E1C428-1|E1C428_CHICK Isoform 1 of SH2 domain containing 4A OS=Gallus gallus OX=9031 GN=SH2D4A PE=4 SV=4 CANONICAL=E1C428-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XYH8-1", "url": "https://www.uniprot.org/uniprotkb/E1C428/entry#A0A8V0XYH8-1", "sequence": { "sequence": "MYRCFWKGTANSSSQGMQVLQTAAEQTVFKKATSFPASTKSVQWKLGADNDVWVWVMGEHPSDKSYAAICEEIQAQRAKRLASEQGKETRETDCAVTQSLQPQPEVLGETEVQGKNKNTVEEQKEEARKNTAGTIGKSQELKKREARDVHQMLADCQMRKGGFSQMKGGHGRNSGEETTVPLKAIPQSHTCSESQKMLQKSDENEPEWQESLRKSKAADEKRRSLARQARDDYRRLSLQGAHRGKQADISKNATAGDRRPLQYPPLPPKPKLLPPAMANGRAVRKEGIQRTISNSAEESIIRWFKEEQFPLRAGYQKTTDTIAPWFHGILTSRKAEELLSKTVPGSFLVRVSEKIKGYVLSYRSAEGCKHFLIDASSDSYSFLGVDQLQHSTLADLVDYHKDEPITSMGKELLLYPCGQEDHEPDYTCLFE", "length": 431, "header": "tr|A0A8V0XYH8-1|E1C428_CHICK Computationally mapped isoform of SH2 domain containing 4A OS=Gallus gallus OX=9031 GN=SH2D4A PE=4 SV=1 CANONICAL=E1C428-1" }, "locus": { "chromosome": "4", "start_pos": 33655237, "end_pos": 33644981, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018448.1", "url": "https://www.ensembl.org/id/ENSGALT00010018448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010100.1", "url": "https://www.ensembl.org/id/ENSGALP00010010100.1" } ] } }, { "isoform_ac": "E1C428-1", "url": "https://www.uniprot.org/uniprotkb/E1C428/entry#E1C428-1", "sequence": { "sequence": "MLKQILSEMYIDPDLLAELSEEQKQILFFKMRQEQIRRWKEREAAADKVSAKKPLPKKASTKSVQWKLGADNDVWVWVMGEHPSDKSYAAICEEIQAQRAKRLASEQGKETRETDCAVTQSLQPQPEVLGETEVQGKNKNTVEEQKEEARKNTAGTIGKSQELKKREARDVHQMLADCQMRKGGFSQMKGGHGRNSGEETTVPLKAIPQSHTCSESQKMLQKSDENEPEWQESLRKSKAADEKRRSLARQARDDYRRLSLQGAHRGKQADISKNATAGDRRPLQYPPLPPKPKLLPPAMANGRAVRKEGIQRTISNSAEESIIRWFKEEQFPLRAGYQKTTDTIAPWFHGILTSRKAEELLSKTVPGSFLVRVSEKIKGYVLSYRSAEGCKHFLIDASSDSYSFLGVDQLQHSTLADLVDYHKDEPITSMGKELLLYPCGQEDHEPDYTCLFE", "length": 453, "header": "tr|E1C428-1|E1C428_CHICK Isoform 1 of SH2 domain containing 4A OS=Gallus gallus OX=9031 GN=SH2D4A PE=4 SV=4 CANONICAL=E1C428-1" }, "locus": { "chromosome": "4", "start_pos": 33655237, "end_pos": 33644115, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018451.1", "url": "https://www.ensembl.org/id/ENSGALT00010018451.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010103.1", "url": "https://www.ensembl.org/id/ENSGALP00010010103.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422487", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BBL1-1", "protein_name": "SH2 domain containing 4A", "gene_name": "SH2D4A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKQILSEMYIDPDLLAELNEEQKQILFFKMREEQVRRWKEREASMEKQESLPVKPRPKKDNGRSVHWKLGADNEVWVWVMGEHHLDKPYDVICDEILAERARLKAEQETPELRKAQPGELSSSSKSKLPSSEGRAPGAGETGNVGDKVAEAGTPGRGCGPAAPLAEQKAPLSSSSSRNIHQMLADSVSRIKEFGFHQKKVSVKKTQDEEIKQIDEERTKEIYKNWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSQRGRSGKGQQGPPGGPQKPKRPPLPPKPHFLSPAGQPHTPLRNQRVRRPASSPAQEDIRRWFQEEQLPLRAGYLADSDSIAPWFHGILTVNRANELLSTCVPGSFLIRVNEKVKGYTLSYQSEDGCKHFLIDASSDSYSFLGVDQLQHASLAELVEYHKEEPITSLGKELLLYPCGQQREPPDYLELFE", "length": 450 }, "evidence": [ { "id": "E1C428", "url": "https://omabrowser.org/oma/group/E1C428/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H6V3-1", "protein_name": "SH2 domain-containing protein 4A", "gene_name": "Sh2d4a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRQILSDMFIDPDLLAELSEEQKQILFYKMREEQIRRWKEREAAMERKESLPVKSRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDLLCDEILAEREHLRTVQDSTLRKAQAAKSTNSQALAKLEPQNVTQKAAAEEASGQGPRATPTKNEDKAHTKEPIKKKEDEDVKQTEDEKTKQIYKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSQRGRSGDGLQNPLAGPQKPRRPPLPPKPLFLHPLGNPPKSLGNQGVIRTESSSTQEDIIRWFKEEQLPFRAGYQKNSDTIAPWFHGILTLKKANDLLSTGVPGSFLIRVSEKIKGYALSYLSEEGCKHFLIDASADSYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDKLPDYLELFE", "length": 412 }, "evidence": [ { "id": "E1C428", "url": "https://omabrowser.org/oma/group/E1C428/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6AYC8-1", "protein_name": "SH2 domain-containing protein 4A", "gene_name": "Sh2d4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRQILSEMFIDPDLLAELSEEQKQILFYKMREEQIRRWKEREAAMERKESLPVKSRPKKENGKSVHWKLGADKQVWVWVMGEHHLDKPYDVLCDEILAEREHLRAAKDAELRKAQSLQFTNSLKVKSLNCDLQAVKKTEPQNVTRKAAAEEATDQGPRAIPTKKDDKAQTKDLTKKKDSEELKQTEDEKTKQIYKNWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSQRGRSGDGLQNPLTGPQKPKRPPLPPKPQFLQPLGSPPKSLGNQGVIRTKTSSTQEDIIRWFKEEQLPFRAGYQKNSDTIAPWFHGILTLKKANELLSTGMPGSFLIRVSEKIKGYALSYLSEEGCKHFLIDASANSYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLFPCGQQDKPPDYLELFQ", "length": 422 }, "evidence": [ { "id": "E1C428", "url": "https://omabrowser.org/oma/group/E1C428/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D7V1-1", "protein_name": "SH2 domain-containing protein 4A", "gene_name": "Sh2d4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRQILSDMFIDPDLLAELSEEQKQILFYKMREEQIRRWKEREAAMERKESLPVKSRPKKENGKSVHWKLGADKQVWVWVMGEHHLDKPYDVLCDEILAEREHLRAAKDSELRKTQSLELANSLKIKSQNCDLQAMKKTEPQNVTRKAASEEASGQGPRAIPTRKDDKAQTKPVKEKDHEEMKQTEDEKTKQIYKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSQRGRSGDGLQNPLTGPQKPRRPPLPPKPQFLQPLGIPPKSLGNQGVIRTEISSAQMDTIRWFKEEQLPFRAGYQKNSDTIAPWFHGILTLKKANELLSTGVPGSFLIRVSEKIKGYALSYLSEEGCKHFLIDASANSYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDKLPDYLELFQ", "length": 421 }, "evidence": [ { "id": "E1C428", "url": "https://omabrowser.org/oma/group/E1C428/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H788-1", "protein_name": "SH2 domain-containing protein 4A", "gene_name": "SH2D4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE", "length": 454 }, "evidence": [ { "id": "E1C428", "url": "https://omabrowser.org/oma/group/E1C428/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C428", "url": "https://www.uniprot.org/uniprotkb/E1C428" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C428", "url": "https://www.uniprot.org/uniprotkb/E1C428" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "E1C428", "url": "https://www.uniprot.org/uniprotkb/E1C428" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "E1C428", "url": "https://www.uniprot.org/uniprotkb/E1C428" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C428-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 453, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C428-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C428" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NC54-1", "uniprot_ac": "F1NC54", "uniprot_id": "F1NC54_CHICK", "mass": { "chemical_mass": 152433.0, "monoisotopic_mass": 152433.0 }, "refseq": { "ac": "XP_015141330", "name": "SH3 domain and tetratricopeptide repeat-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141330" }, "gene_names": [ { "name": "SH3TC1", "type": "recommended", "evidence": [ { "id": "F1NC54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC54" } ] }, { "name": "SH3TC1", "type": "synonym", "evidence": [ { "id": "XP_015141330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141330" } ] } ], "protein_names": [ { "name": "SH3 domain and tetratricopeptide repeat-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015141330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141330" } ] }, { "name": "SH3 domain and tetratricopeptide repeats 1", "type": "synonym", "evidence": [ { "id": "F1NC54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC54/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141330" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NC54", "url": "https://www.uniprot.org/uniprotkb/F1NC54" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH3TC1", "url": "https://www.uniprot.org/uniprotkb/F1NC54", "locus": { "chromosome": "4", "start_pos": 80353876, "end_pos": 80322156, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009700", "url": "https://www.ensembl.org/id/ENSGALG00010009700" } ] } } ], "crossref": [ { "id": "ENSGALG00000015568", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015568", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11885", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11885", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422867", "url": "https://www.ncbi.nlm.nih.gov/gene/422867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422867", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTNEQQG", "url": "https://omabrowser.org/oma/group/FTNEQQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XYN6", "url": "https://www.orthodb.org/?gene=A0A8V0XYN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y374", "url": "https://www.orthodb.org/?gene=A0A8V0Y374", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NC54", "url": "https://www.orthodb.org/?gene=F1NC54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22647", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22647", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22647:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22647:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XYN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XYN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y374", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y374", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y374-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y374-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NC54", "url": "https://www.uniprot.org/uniprotkb/F1NC54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NC54-1", "url": "https://www.uniprot.org/uniprotkb/F1NC54-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLAAGGSSVSVLSSKVTTELGIPAPSLEGKQDSNLERKETEQGRCVPGWICETAVATVSAARGGDKTDTLQEQMDYPQNEKCMNVSSRTLLSQAENFPTDISLKLTMVRRKSGRPDPRLQRQLRGQLRLLENDSREVTAVFSELSARLLSIHSDQDLIVVTFKTFEEIWKFLTYHSLGFVNHCMENLFLDQSFWLYSQEEEETGIEVCINEKSLNLMYRSLLVQEGAFFVLCPDNLVRKITATDCEINTYFEAGAFTADVAGGSVDGDMTMPSNVPLEPLIPFHQWFLKVYSDPIDVAYKTESKSIRQVATGSCLAVMNYDSAVPEEISFQEGDEIEILGYLIECMEWFVGRHLFTGHVGFVKTSHVKLDLPGNKAADLDFLKAEELSFFPQEKNVEEVVHLLKQTSITDVCSVYRIDQLEEQEFQKTRECEIPCPHSNMATTSKKNGKIEEFVEKFKKLEVTQAEGPATERKESASSSHTEIFPSPEGPCFYIYQDDGQESDVFESLLLFLNNKEYESDFKNLYDFSYTFINSMFYGFSEEDELLSFFSVARELAKKAGMSWALARLCFLLGRLSVKKVKFSQARVYFEEALGAVTGGFTDLYFVIALYTNLTVIYLTQKNKEKCSHVFDKATSLLMGIPNHICSADLESDILKHALKRTILSQNKHAEARACFLLAKHYTARKQHEEALPFLERLQLLFNDLGLQNNLSKNCYFNLAESYNEKCLPHIVLSCIKVSSSQNSSTLMDSLKRIDLVIKNAPKLYGLRKLRQILPSQIAPYLTQALSSAFTNEQQGLCSTIYLSLAKLYSHHKQYGKAIIYMMKALDSDTSAKPEETINYLVSLAWLYILYRQYDVAATILNAVVDSSGSNPQQLGVAYNMLAIALKRTNNTKKAVESCYKALRLSEEANMTHNQAISLANFGMLCLHAAAGKLAEHYYIKAVKLFAKLPSMDCGQEFIQTLLQLGRYYVNRTQREKGRFYYEWAFLVAMEISHLESQLQAIKLLCQFYSTVVPNEAQCVIYNEYQLSLARKMSNKVLEGQILETISQLYLSLGTERAYRSALEYTKRSLGIFIDLQKKEREAYAWLRAGKIYYILRQNELVDLYIQVAQDAALCTGDPNLAMELFEAAGDIFFNGKWEKEKAVPFYRDRALPLAVESGNKNTELRLCNKLVELLVNLKVYEESMEYAKASLILSVNLGNQLNERIAYHRLAAIHHHLGHCELAEHFYLKALSLCSSPLEFEEETLYYVKVYLNLGDIIFYDLKDPFDAAGYYQLALAAAMDLGNKKAQLKIYTRLAIIYHNFLVDREMSLFFYQKARTFATELNVRRINLAPDQCYKSL", "length": 1341, "header": "tr|F1NC54-1|F1NC54_CHICK Isoform 1 of SH3 domain and tetratricopeptide repeats 1 OS=Gallus gallus OX=9031 GN=SH3TC1 PE=4 SV=2 CANONICAL=F1NC54-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XYN6-1", "url": "https://www.uniprot.org/uniprotkb/F1NC54/entry#A0A8V0XYN6-1", "sequence": { "sequence": "MSSLAAGGSSVSVLSSKVTTELGIPAPSLEGKQDSNLERKETEQGRCVPGWICETAVATVSAARGGDKTDTLQEQMDYPQNEKCMNVSSRTLLSQAENFPTDISLKLTMVRRKSGRPDPRLQRQLRGQLRLLENDSREVTAVFSELSARLLSIHSDQDLIVVTFKTFEEIWKFLTYHSLGFVNHCMENLFLDQSFWLYSQEEEETGIEVCINEKSLNLMYRSLLVQEGAFFVLCPDNLVRKITATDCEINTYFEAGAFTADVAGGSVDGDMTMPSNVPLEPLIPFHQWFLKVYSDPIDVAYKTESKSIRQVATGSCLAVMNYDSAVPEEISFQEGDEIEILGYLIECMEWFVGRHLFTGHVGFVKTSHVKLDLPGNKAADLDFLKAEELSFFPQEKNVEEVVHLLKQTSITDVCSVYRIDQLEEQEFQKTRECEIPCPHSNMATTSKKNGKIEEFVEKFKKLEVTQAEGPATERKESASSSHTEIFPSPEGPCFYIYQDDGQESDVFESLLLFLNNKEYESDFKNLYDFSYTFINSMFYGFSEEDELLSFFSVARELAKKAGMSWALARLCFLLGRLSVKKVKFSQARVYFEEALGAVTGGFTDLYFVIALYTNLTVIYLTQKNKEKCSHVFDKATSLLMGIPNHICSADLESDILKHALKRTILSQNKHAEARACFLLAKHYTARKQHEEALPFLERLQLLFNDLGLQNNLSKNCYFNLAESYNEKCLPHIVLSCIKVSSSQNSSTLMDSLKRIDLVIKNAPKLYGLRKLRQILPSQIAPYLTQALSSAFTNEQQGLCSTIYLSLAKLYSHHKQYGKAIIYMMKALDSDTSAKPEETINYLVSLAWLYILYRQYDVAATILNAVVDSSGSNPQQLGVAYNMLAIALKRTNNTKKAVESCYKALRLSEEANMTHNQAISLANFGMLCLHAAAGKLAEHYYIKAVKLFAKLPSMDCGQEFIQTLLQLGRYYVNRTQREKGRFYYEWAFLVAMEISHLESQLQAIKLLCQFYSTVVPNEAQCVIYNEYQLSLARKMSNKVLEGQILETISQLYLSLGTERAYRSALEYTKRSLGIFIDLQKKEREAYAWLRAGKIYYILRQNELVDLYIQVAQDAALCTGDPNLAMELFEAAGDIFFNGNQLNERIAYHRLAAIHHHLGHCELAEHFYLKALSLCSSPLEFEEETLYYVKVYLNLGDIIFYDLKDPFDAAGYYQLALAAAMDLGNKKAQLKIYTRLAIIYHNFLVDREMSLFFYQKARTFATELNVRRINLAPDQCYKSL", "length": 1278, "header": "tr|A0A8V0XYN6-1|F1NC54_CHICK Computationally mapped isoform of SH3 domain and tetratricopeptide repeats 1 OS=Gallus gallus OX=9031 GN=SH3TC1 PE=4 SV=1 CANONICAL=F1NC54-1" }, "locus": { "chromosome": "4", "start_pos": 80353230, "end_pos": 80331124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023165.1", "url": "https://www.ensembl.org/id/ENSGALT00010023165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013402.1", "url": "https://www.ensembl.org/id/ENSGALP00010013402.1" } ] } }, { "isoform_ac": "A0A8V0Y374-1", "url": "https://www.uniprot.org/uniprotkb/F1NC54/entry#A0A8V0Y374-1", "sequence": { "sequence": "MSSLAAGGSSVSVLSSKVTTELGIPAPSLEGKQDSNLERKETEQGRCVPGWICETAVATVSAARGGDKTDTLQEQMDYPQNEKCMNVSSRTLLSQAENFPTDISLKLTMVRRKSGRPDPRLQRQLRGQLRLLENDSREVTAVFSELSARLLSIHSDQDLIVVTFKTFEEIWKFLTYHSLGFVNHCMENLFLDQSFWLYSQEEEETGIEVCINEKSLNLMYRSLLVQEGAFFVLCPDNLVRKITATDCEINTYFEAGAFTADVAGGSVDGDMTMPSNVPLEPLIPFHQWFLKVYSDPIDVAYKTESKSIRQVATGSCLAVMNYDSAVPEEISFQEGDEIEILGYLIECMEWFVGRHLFTGHVGFVKTSHVKLDLPGNKAADLDFLKAEELSFFPQEKNVEEVVHLLKQTSITDVCSVYRIDQLEEQEFQKTRECEIPCPHSNMATTSKKNGKIEEFVEKFKKLEVTQAEGPATERKESASSSHTEIFPSPEGPCFYIYQDDGQESDVFESLLLFLNNKEYESDFKNLYDFSYTFINSMFYGFSEEDELLSFFSVARELAKKAGMSWALARLCFLLGRLSVKKVKFSQARVYFEEALGAVTGGFTDLYFVIALYTNLTVIYLTQKNKEKCSHVFDKATSLLMGIPNHICSADLESDILKHALKRTILSQNKHAEARACFLLAKHYTARKQHEEALPFLERLQLLFNDLGLQNNLSKNCYFNLAESYNEKCLPHIVLSCIKVSSSQNSSTLMDSLKRIDLVIKNAPKLYGLRKLRQILPSQIAPYLTQALSSAFTNEQQGLCSTIYLSLAKLYSHHKQYGKAIIYMMKALDSDTSAKPEETINYLVSLAWLYILYRQYDVAATILNAVVDSSGSNPQQLGVAYNMLAIALKRTNNTKKAVESCYKALRLSEEANMTHNQAISLANFGMLCLHAAAGKLAEHYYIKAVKLFAKLPSMDCGQEFIQTLLQLGRYYVNRTQREKGRFYYEWAFLVAMEISHLESQLQAIKLLCQFYSTVVPNEAQCVIYNEYQLSLARKMSNKVLEGQILETISQLYLSLGTERAYRSALEYTKRSLGIFIDLQKKEREAYAWLRAGKIYYILRQNELVDLYIQVAQDAALCTGDPNLAMELFEAAGDIFFNGKWEKEKAVPFYRDRALPLAVESGNKNTELRLCNKLVELLVNLKVYEESMEYAKASLILSVNLGNQLNERIAYHRLAAIHHHLGHCELAEHFYLKALSLCSSPLEFEEETLYYVKVYLNLGDIIFYDLKVKNTKNCCGKSLHVVMFFHIILLNCAFRI", "length": 1294, "header": "tr|A0A8V0Y374-1|F1NC54_CHICK Computationally mapped isoform of SH3 domain and tetratricopeptide repeats 1 OS=Gallus gallus OX=9031 GN=SH3TC1 PE=4 SV=1 CANONICAL=F1NC54-1" }, "locus": { "chromosome": "4", "start_pos": 80352872, "end_pos": 80331124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023170.1", "url": "https://www.ensembl.org/id/ENSGALT00010023170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013406.1", "url": "https://www.ensembl.org/id/ENSGALP00010013406.1" } ] } }, { "isoform_ac": "F1NC54-1", "url": "https://www.uniprot.org/uniprotkb/F1NC54/entry#F1NC54-1", "sequence": { "sequence": "MSSLAAGGSSVSVLSSKVTTELGIPAPSLEGKQDSNLERKETEQGRCVPGWICETAVATVSAARGGDKTDTLQEQMDYPQNEKCMNVSSRTLLSQAENFPTDISLKLTMVRRKSGRPDPRLQRQLRGQLRLLENDSREVTAVFSELSARLLSIHSDQDLIVVTFKTFEEIWKFLTYHSLGFVNHCMENLFLDQSFWLYSQEEEETGIEVCINEKSLNLMYRSLLVQEGAFFVLCPDNLVRKITATDCEINTYFEAGAFTADVAGGSVDGDMTMPSNVPLEPLIPFHQWFLKVYSDPIDVAYKTESKSIRQVATGSCLAVMNYDSAVPEEISFQEGDEIEILGYLIECMEWFVGRHLFTGHVGFVKTSHVKLDLPGNKAADLDFLKAEELSFFPQEKNVEEVVHLLKQTSITDVCSVYRIDQLEEQEFQKTRECEIPCPHSNMATTSKKNGKIEEFVEKFKKLEVTQAEGPATERKESASSSHTEIFPSPEGPCFYIYQDDGQESDVFESLLLFLNNKEYESDFKNLYDFSYTFINSMFYGFSEEDELLSFFSVARELAKKAGMSWALARLCFLLGRLSVKKVKFSQARVYFEEALGAVTGGFTDLYFVIALYTNLTVIYLTQKNKEKCSHVFDKATSLLMGIPNHICSADLESDILKHALKRTILSQNKHAEARACFLLAKHYTARKQHEEALPFLERLQLLFNDLGLQNNLSKNCYFNLAESYNEKCLPHIVLSCIKVSSSQNSSTLMDSLKRIDLVIKNAPKLYGLRKLRQILPSQIAPYLTQALSSAFTNEQQGLCSTIYLSLAKLYSHHKQYGKAIIYMMKALDSDTSAKPEETINYLVSLAWLYILYRQYDVAATILNAVVDSSGSNPQQLGVAYNMLAIALKRTNNTKKAVESCYKALRLSEEANMTHNQAISLANFGMLCLHAAAGKLAEHYYIKAVKLFAKLPSMDCGQEFIQTLLQLGRYYVNRTQREKGRFYYEWAFLVAMEISHLESQLQAIKLLCQFYSTVVPNEAQCVIYNEYQLSLARKMSNKVLEGQILETISQLYLSLGTERAYRSALEYTKRSLGIFIDLQKKEREAYAWLRAGKIYYILRQNELVDLYIQVAQDAALCTGDPNLAMELFEAAGDIFFNGKWEKEKAVPFYRDRALPLAVESGNKNTELRLCNKLVELLVNLKVYEESMEYAKASLILSVNLGNQLNERIAYHRLAAIHHHLGHCELAEHFYLKALSLCSSPLEFEEETLYYVKVYLNLGDIIFYDLKDPFDAAGYYQLALAAAMDLGNKKAQLKIYTRLAIIYHNFLVDREMSLFFYQKARTFATELNVRRINLAPDQCYKSL", "length": 1341, "header": "tr|F1NC54-1|F1NC54_CHICK Isoform 1 of SH3 domain and tetratricopeptide repeats 1 OS=Gallus gallus OX=9031 GN=SH3TC1 PE=4 SV=2 CANONICAL=F1NC54-1" }, "locus": { "chromosome": "4", "start_pos": 80353230, "end_pos": 80331124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023161.1", "url": "https://www.ensembl.org/id/ENSGALT00010023161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013398.1", "url": "https://www.ensembl.org/id/ENSGALP00010013398.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422867", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MJK4-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 1", "gene_name": "Sh3tc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSSREEEATSEELSTMGQDLEEPPGGCSHGDQIHSVSVSLPIGQERAGPEEAVRSDVASPPSMAELAAETPSGRKAVFPTDLTLQLLAVRRKSGLRSPSLQQALRSRLRLLENDSREVARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLENLLVDQTFWLLSPSEEEETAILMYVSKEALKQTHKKLLTQEGPFFVRCPEHRVRMMMGPQGAGKGPQALRRASGVPLGVAILETNSSSPMPSTSSNVEAAEADPEPLTPFHQWTLRVPWDPIDESMDGPGTPDAQLMGLGLASAVGDFQGSGPEEMSFCVGDVIEIIGAQVPGLPWCVGRHVASGQVGFVRTGLVSMQGPASDLESAIFLSEEERSFFRSEGHFSDEDARRLLSRTSCTDVCTTCSLDWLEEAEGEQLEQQELSLPHLNPEPHETLHMVKDILERCKACPDHPEDPVSWSLGEVSNRVSSPDLEEPPFCLDPEVDWTDPEPLDSLLQVLNAPGYEAHFRGLYDISLPWLSTALCGFDDEEELAGCLAQARGVAKKVNLGMALARLCLLLGRLCARKLKLSQARVYFEEALGALEGSFGDLSLVAAVYTSLATVYLKQKNGEKCVQVAPKAAALLLGTPGHAYSTDTELLKYALRRAICGLSPQAEARACFLLARHYTHLKQPEEALPYLERLLRLNRDVGTPQASWPKDCYLLLADIYGRKCLPHLALSCLRVSSLWTRCSLASSLRSVDLVLRNAPGPNSQRRANHRLPTQIAYYLRKALASLTPGTGQALCGPLYASLAQLYSHHQQHNQAIAFMSQAAEADTAAGIYPVVDRLVALAWLHMLCGKNLVAMDILKSILDAAVANKDQECVMTNMVAMALKRTGRTRQAAEGYFRALHMAYSQGHLKSQAVVLANFGALCLQAGARSLAQHYLREAVGLFSQLPSSVCGRDFTQVLLWLGQLCTRRALHQQAKCYYEWAFLVAVEMDHLESQLQAVQKLCHFYSKVMPNEVRCVIYHEFQLALARRTADKVLEGQLLEAISQLYLSLGTERAYKSALDYTKRSLGIFIDLQQKEKEARAWLQAGKIYYILRQNELVDLYIQVAQNAALYTGDPKLGLELFEAAGDIFFNGTWEREKAVSFYRDRALPLAVTIGNQEAELRLCNKLVALLSALEAPQEGLEFAHEALALSITLGDRLNERVAYHRLATLHHQLGHGELAEHFFLKALSLCNSPLEFDEETLYYVKVYLVLGDIIFYDLKDPFDAAGYYQLALAAAVDLGHKKAQLKIYTRLATIYHHFLMDREMSLFFYQKARTFASELNLRRTNLVPQRFCGRTPWLAPGYPS", "length": 1341 }, "evidence": [ { "id": "F1NC54", "url": "https://omabrowser.org/oma/group/F1NC54/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZLQ9-1", "protein_name": "SH3 domain and tetratricopeptide repeats 1", "gene_name": "Sh3tc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSFREEEATSEDLSTMGQGPEEPPGGCSLEDKIQSISMGLPTSQERTGPEEAEATTVRGDVAPPCGMVGQAAEPPSNQMAVYPTDLTLQLLAVRRKSGLRSPSLQQTLRSRLRLLENDSREVARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLENLLVDQTFWLLSPSEEEETAILIYVNKDALKQTHKSLLAQEGSFFVLCPDHCVRRTKEPQGAGKGPQTLRRASGVTLGVPVVETVSSSPTPSMSSKAEAVEAEPEPLTPFHQWTLRVPWDPIDESMSGPGTPDAQFMRFGLASAIADFQGSGPEEMSFSVGDVIEIVGAQVPGLPWCLGQHMASGQVGFVRTGLVRMQGPASDLESSIFLSEEERSFFRSEAHFSDEDARRLLCRTSGTDVCTTCSLDWLEEAEGEQLEQQEMSLPHLNPEPHESLHMVKNVLEKCKACPDHPEDPVSWSLGAVSSRVSSPDLEEPPFCLDPDDDWTDPEPPDSLLQVLSAPGYRAQFRSLYDISLPCLSTALYSFDDEEELAERLAQARGVAKKVDLGMALARLCLLLGRLCARKLKLSQARVYFEEALGALEGSFGDLSLVAAVYSSLATVYLKQKNGEKCVQLAPKAAALLLGTPGHSCSTDAELLKYALRRVVCGLSPQAEARACFLLARHYTHLKQPEEALPYLERLLRLNRDVGTPQASWPEDCYLLLADIYGRKCLPHLALSCLKVSSLWTRCSLAGSLRSVDLVLQNAPGPNSQRSTGHSLPSQIAHYLRQALASLPPGTGQTLRGPLYASLAQLYSYHQQYGQAIAFMSQAAEADTAAGVHPVVDRLVALAWLHLLCGKSLVAMDILKCVSDAAVANKDQECVMMNMVAMALKRMGRTRQAAEGYFRALHMAYSQGHLQSQAVVLANFGALCLQAGARSLAQHYLREAVGLFSQLPSGVCGRDFTQVLLWLGQLCTRRTLPQQAKCYYEWAFLVAVETDHLESQLQAVQKLCHFYSKVMPNEVRCVIYHEFQLALARKTADKVLEGQLLEAISQLYLSLGTERAYKSALDYTKRSLGIFIDLQQKEKEARAWLQAGKIYYILRQNELVDLYIQVAQNAALYTGDPKLGLELFEAAGDIFFNGTWEREKAMKVPCTHDRALPLAVTVGDQEVELRLCNKLVALLSALEAPQEGLEFAHEALALSITLGDRLNERVAYHRLATLHHRLGHGELAEHFFLKALSLCTSPLEFDEETLYYVKVYLVLGDIIFYELKDPFDAAGYYQLALAAAVDLGHKKAQLKIYTRLATIYHNFLMDREMSLFFYQKARTFASELNLRRTNLVPQHFCSRAPWLAPGYPS", "length": 1347 }, "evidence": [ { "id": "F1NC54", "url": "https://omabrowser.org/oma/group/F1NC54/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QHY2-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 1 isoform X1", "gene_name": "sh3tc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAAARRNSSKTGNGVEPDPDRVRTLRRELSNEYTRNELDNIMESSSRDYRISRGSFKGTPGASDDNVPTVLAMQLTMVEGPDRLPADENTQEVLCRKLCVLEADLSGVVTLISELSAHFVSIYSEERTIFITFKTIDDIWRFSTYYRMGFLGQCMENLLMDQEFWLTSLDHHSGIEISIKEETLNLMYKGFLMQEGSFFGCCTANQMFDSSTSGKDLYLEKGDIALFEPPFLGSGWTVLSLAEGSRGTKAKPALEPVTPFHEWFLKSCPETVLVGGGKDTIDLPFQIAVGVCETIEDYDADGPDELSFQTGERIIIQGLLVACFEWFMGQSEKTGDTGLVKTRLVKATGSFCESSDMFLKDEDRQIVTLDHEQIKEETLSLLKKTCQCDVGTNYKLDVAKEISGSVQSKSHQTEVSNLKQKVSHVLSEAQETQRNEVSALIINHQKEKQRNDTEVSQDTPRFSVCSDKEGSSPDEHHALLSFLSSREHQPEFTLLYRAYPEFLMTHFEGHSDEEDIVTYLGIARELARKKRVSWAQSRICFLLGQLCAGRSKFSQARVYYEEALNVPRDSFSDMLLLSALYSNLALIYLTQKNHEKFFALSERFSALLMAVPDCLFGCEDPEVLKYVLKKAVLAKSQLAEARACFLLAKLHLKIKDAVSVVPFIERLLILADELPEVCDEAMCHVSLVLARLYSEQGLPRLAESCARRASLQVGVTVSHCLCGVSLLLENAPELHGVSIPTQVAPFLTRAAALAPLHNDPTLVHIHALCLSWLFHRHNMPERAVRYMCAILEHSSMSSIGKSDATTAFIWLAWLYICNQQPGTALEVLDAVLASLPEHCTTHLEGVVYNMRAISYRHSADIRQAAESYQAAIEICEEFEDRHNWAVALANFGFMCLQVKAKRLAEENLCQSMELFSGLEDEGHELSFILVLLQLGRHFISQGNSESGKIYYEWALLIATYIDNIESQLHTTRHLCELYEDVCPDEAQCIIYNEHQLNLLQRIGDKSSEAEILEKISQLYLNLATEKANRAALDYTKRSLAIFIDLGKKRKEAHAWLRAGKIYHILQQTELVDLYVQVAQDMALNTGDTLFTLEMLEAAGDVFFNSSQDRDKAICFYRDRALPIAVKTSSVGSQLRLCNKLSELLLQLGQSSEALEFAQTALDISVSLADRLNERVAFHRLATLYHCLGQFEMAEHHFLKALSLCPSPLQYDEEALYYVRVYQTLGDIIFYDVKDPFDAAGYYHLALAAAMDLGNKRSQLQLCTRLATIYHNFLMDRELSLFFYQRARVFANDLHIRRINLAPDYSFRSTSQYKHTITGAAR", "length": 1322 }, "evidence": [ { "id": "F1NC54", "url": "https://omabrowser.org/oma/group/F1NC54/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3MZW4-1", "protein_name": "SH3 domain and tetratricopeptide repeats 1", "gene_name": "SH3TC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCAFLPGQASRGRDHREGPEQEQRQRSAWHAEPLAVRPPSAMEGPEEPAPRGNGPAGPWGGSGDHGVREVAKSTSVSWERPRPEEAKATVRGDLTLQLLAVRRKSGLPDPNLQQALRGQLRLLENESCEVARTLGELSARLLSIHSDQDRLVVTFKTFEEIWKFSTYHALGFTHHCLENLLMDQAFWLLEPDEDQETAVRVQVDAEALRLAYESLLVQEGPFFVLCPDHHVRVRNGPQPFRRPPRGPQADAATAVDSPAPSPGTSSEAEGAAAAAPEPLIPFHQWALRVPKDSVNDPLGGPVAPDVQLMAMGPALAVADCQGSGPEEMTFRSGDRIEILGAQVPGLPWCLGRHTASGQVGFVRTSLINVQGQASDLENVIFLSEEERSFFSREGHFSEEEARQLLRRTSSTNVCTMYRLDTSEEAETQQQQEEQEMSPPCLNPEPQEILQTVKNVLKQCKSCRGCPEEPGSPGVHRASSGASLPDTEEPFFCLDTGDDWADPEALGSQLLFLDSPGFQAGFQGLYDLSPPTLSSVFGGFTDEEELVRRLAEARGVAKKAGLPMALARLCFLLGRLCVRQLKLSQARVYFEEALGVLGGRFGDLVLVAAVYTSLASVHLRQKNKEKCAQVVPKALALLLGTPGHVGSSEADSSLLTLALRRAISSRSPQAEARACFLLAKHHARLKQPEEAMPFLERLLLLLPEAAGTPGTSWPMDCYLLLASIYSQRCLPHLALSCIRVASLRAQGSLGSALRSAALVLQNSPRLPLLPAQLAHYLRRALATLASGSGQALHGPVYASLAQLYSQHGWQGRAIAFMAQAVETDARLGGCTVVDRLVALAWLHVLHRQSPAALGILESLLEAAVATPDQEGLITNMMAIALKRTGRTRRAAESYYRALRVARRLSRPQNEAVVLANFGALCLQAGAGGLAQHYLLEAVKLFSRLPSREGSPDFTRVLLRLGDLCTRRALARQAKCYYEWAFLVAVEMDHWESQLLAVQRLCHFYSAVVPNEARCVVYHEFQLSLARRVNDKVLEGQLLETISQLYLSLGTERAYRSALEYTKRSLGVFIDLLKKDKEAHAWLQAGKIYYVLRQSELVDLYIQAAQNAALYTGDPGLGLQLFEEAGDIFFNGTWDREKAVSFYRDRALPLAVSTGSREAELRLCNKLSALLAETEAPQEGLEFAHTALALSLTLGDQLNQRVACHRLAALHHRLGHGELAEHFYLKALSLCTSPLEFDEETLYYVKVYLALGNIIFYDLKDPLDAAGYYQLALAAAMGLGSKRAQMKLCARLASIYHHSLLDRETSLFFYQKARTFATELSVRRGRLAPGPPS", "length": 1331 }, "evidence": [ { "id": "F1NC54", "url": "https://omabrowser.org/oma/group/F1NC54/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9F6-1", "protein_name": "SH3 domain and tetratricopeptide repeats 1", "gene_name": "Sh3tc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSFREEEEEATSEELFTMGRGPEEPRGSCSPEDQIQSVSMGLPTGQERTGSAEAEATVRGDVAPPRIVVGLAAEPPPSQMTVYPTDLTLQLLAVRRKSGLRSPSLQQALRSRLRLLENDSREVARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLENLLVDQTFWLLSPSEEEETAILMYVNKDALKQTHKNLLTQEGSIFVLCPDHRVRRTIGPKGAGKGPQTLRRASGVPLGVAILETDSSSPTPNMSSNVEAAEAEPEPLTPFHQWTLRVPWDPIDESMSGPGTPDAQLMRFGLASAIADFQGSGPEEMSFSVGDVIEILGAQVPGLPWCVGRHMASGQVGFVRTGLVSMQGPASDLESAIFLSEEERSFFRSEGHFSDEDARRLLSRTSGTDVCTTCSLDWLEEAEGEQLEQREMSLPHLNPEPHGTLQMVKNILEKCKACPDHPEAPVSWSLGGVSRRASSLDLEEPRFCLDPEDDWTDPEPLDSLLQVLNAPGYGAHFRSLYDISLPWLSTALYGFDDEEELAERLAQARGVAKKVDLSMALARLCLLLGRLCARKLKLSQARVYFEEALGALEGSFGDLSLVAAVYSSLTTVYLKQKNAEKCVQVAPKAAALLLGTPGHSCNADAELLKYALRRVICGLSPQAEARACFLLARHYTHLKQPEEALPYLERLLRLNRDAGSPQASWPEDCYLLLADIYGRKCLPHLALSCLRVSSLWTRCSLPGSLRSVDLVLQNVPGPNSQRRAGHSLPSQIAYYLRQALASLAPGTGQALRGPLYASLAQLYSHHQQYSQAIAFMSQAAEADTAAGVHPVVDRLVALAWLHMLCGNSLVAMDILKCISDAAVANKDQECVMMNMVAMALKRMGRTRQAAEGYFRALHMAYAQGHLQSQAVVLANFGALCLQAGARSLAQHYLREAVGLFSQVPSGVCGRDFTQVLLWLGQLCTRRALPQQAKCYYEWAFLVAVETDHLESQLQAVQKLCLFYSKVMPNEVRCVIYHEFQLALARKTANKVLEGQLLEAISQLYLSLGTERAYKSALDYTKRSLGIFIDLQQKEKEARAWLQAGKIYYILRQNELVDLYIQVAQNAALYTGDPKLGLELFEAAGDIFFNGTWEREKAVSFYRDRALPLAVTVGDQEVELRLCNKLVALLSALEAPQEGLEFAHEALALSITLGDRLNERVAYHRLATLHHRLGHGELAEHFFLKALSLCSSPLEFDEETLYYVKVYLVLGDIIFYDLKDPFDAAGYYQLALAAAVDLGHKKAQLKIYTRLATIYHHFLVDREMSLFFYQKARTFASELNLRRTNLVPQRFCGRAPWLAPGHPS", "length": 1346 }, "evidence": [ { "id": "F1NC54", "url": "https://omabrowser.org/oma/group/F1NC54/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TE82-1", "protein_name": "SH3 domain and tetratricopeptide repeat-containing protein 1", "gene_name": "SH3TC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENLPAVTTEEPTPMGRGPVGPSGGGSTRDQVRTVVMRPSVSWEKAGPEEAKAPVRGDEAPPARVAGPAAGTPPCQMGVYPTDLTLQLLAVRRKSRLRDPGLQQTLRGQLRLLENDSREMARVLGELSARLLSIHSDQDRIVVTFKTFEEIWKFSTYHALGFTHHCLANLLMDQAFWLLLPSEEEETAIQVHVDENALRLTHESLLIQEGPFFVLCPDHHVRVMTGPRDAGNGPQALRQASGAPQGEAAPETDSSPPSPSVSSEEVAVAAAPEPLIPFHQWALRIPQDPIDDAMGGPVMPGNPLMAVGLASALADFQGSGPEEMTFRGGDLIEILGAQVPSLPWCVGRHAASGRVGFVRSSLISMQGPVSELESAIFLNEEEKSFFSEGCFSEEDARQLLRRMSGTDVCSVYSLDSVEEAETEQPQEKEIPPPCLSLEPQETLQKVKNVLEQCKTCPGCPQEPASWGLCAASSDVSLQDPEEPSFCLEAEDDWEDPEALSSLLLFLNAPGYKASFRGLYDVALPWLSSVFRSFSDEEELTGRLAQARGAAKKAGLLMALARLCFLLGRLCSRRLKLSQARVYFEEALGALEGSFGDLFLVVAVYANLASIYRKQKNREKCAQVVPKAMALLLGTPDHICSTEAEGELLQLALRRAVGGQSLQAEARACFLLARHHVHLKQPEEALPFLERLLLLHRDSGAPEAAWLSDCYLLLADIYSRKCLPHLVLSCVKVASLRTRGSLAGSLRSVNLVLQNAPQPHSLPAQTSHYLRQALASLTPGTGQALRGPLYTSLAQLYSHHGCHGPAITFMTQAVEASAIAGVRAIVDHLVALAWLHVLHGQSPVALDILQSVRDAVVASEDQEGVIANMVAVALKRTGRTRQAAESYYRALRVARDLGQQRNQAVGLANFGALCLHAGASRLAQHYLLEAVRLFSRLPLGECGRDFTHVLLQLGHLCTRQGPAQQGKGYYEWALLVAVEMGHVESQLRAVQRLCHFYSAVMPSEAQCVIYHELQLSLACKVADKVLEGQLLETISQLYLSLGTERAYKSALDYTKRSLGIFIDLQKKEKEAHAWLQAGKIYYILRQSELVDLYIQVAQNVALYTGDPNLGLELFEAAGDIFFDGAWEREKAVSFYRDRALPLAVTTGNRKAELRLCNKLVALLATLEEPQEGLEFAHMALALSITLGDRLNERVAYHRLAALQHRLGHGELAEHFYLKALSLCNSPLEFDEETLYYVKVYLVLGDIIFYDLKDPFDAAGYYQLALAAAVDLGNKKAQLKIYTRLATIYHNFLLDREKSLFFYQKARTFATELNVRRVNLPPLPLCGWAPWLAPSHPR", "length": 1336 }, "evidence": [ { "id": "F1NC54", "url": "https://omabrowser.org/oma/group/F1NC54/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" }, { "start_pos": 891, "end_pos": 893, "annotation": "n_glycosylation_sequon" }, { "start_pos": 911, "end_pos": 913, "annotation": "n_glycosylation_sequon" }, { "start_pos": 972, "end_pos": 974, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 614, "end_pos": 616 }, { "start_pos": 711, "end_pos": 713 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 86, "end_pos": 88 }, { "start_pos": 891, "end_pos": 893 }, { "start_pos": 911, "end_pos": 913 }, { "start_pos": 972, "end_pos": 974 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NKD2-1", "uniprot_ac": "F1NKD2", "uniprot_id": "F1NKD2_CHICK", "mass": { "chemical_mass": 48962.0, "monoisotopic_mass": 48962.0 }, "refseq": { "ac": "XP_416761", "name": "divergent protein kinase domain 2B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416761" }, "gene_names": [ { "name": "CXorf36", "type": "recommended", "evidence": [ { "id": "F1NKD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKD2" } ] }, { "name": "CXorf36", "type": "synonym", "evidence": [ { "id": "XP_416761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416761" } ] } ], "protein_names": [ { "name": "Divergent protein kinase domain 2B", "type": "synonym", "evidence": [ { "id": "F1NKD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKD2/entry#names_and_taxonomy" } ] }, { "name": "divergent protein kinase domain 2B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416761" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_416761.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416761" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKD2", "url": "https://www.uniprot.org/uniprotkb/F1NKD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CXorf36", "url": "https://www.uniprot.org/uniprotkb/F1NKD2", "locus": {} } ], "crossref": [ { "id": "F1NKD2", "url": "https://alphafold.ebi.ac.uk/entry/F1NKD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000016215", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000016215", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418555", "url": "https://www.ncbi.nlm.nih.gov/gene/418555", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418555", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418555", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQRFQKW", "url": "https://omabrowser.org/oma/group/TQRFQKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XYY4", "url": "https://www.orthodb.org/?gene=A0A8V0XYY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NKD2", "url": "https://www.orthodb.org/?gene=F1NKD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32073:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32073:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416761", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XYY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XYY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKD2", "url": "https://www.uniprot.org/uniprotkb/F1NKD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKD2-1", "url": "https://www.uniprot.org/uniprotkb/F1NKD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRWICCLCSRVADWLMLLLVLARSSNPSAAATASPSAPHVRPSYSFGRTFLGLDKCNACIGTSICKKFFKEEIRFDTWLSSHLKLPPSYLLSYLGNYTDDAQSWRMVDITRLTTKYQHDRADQHICTSLLKTKTCSLERALRRTHRFQKWLRAKRLTPDLVQGLSSPMLRCPSQRLLDRIVRRYAEVPDAGSIYMDHLTDQDKLRLLYTLSVNSHPILLQIFPDVEGWPFPRYLGSCGRLVVSASTRPLRDFFRAAPEVAADLALQLLAVLHSMGTNDLNYFFYFTRVDVGTFGVFSNGHLFIRDASTLGIIDKEEGSQPIDGQQEYKDIFSCLTVDCQSAFVSCNSIREKQSLVMVCQELLPKLLRGKFLPPVQEKIDSFLQHCAEGLADDQDVNEAMAKLAQLLKPLRSCDSRFAYRYPDCKYSDKY", "length": 430, "header": "tr|F1NKD2-1|F1NKD2_CHICK Isoform 1 of Divergent protein kinase domain 2B OS=Gallus gallus OX=9031 GN=CXorf36 PE=3 SV=4 CANONICAL=F1NKD2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XYY4-1", "url": "https://www.uniprot.org/uniprotkb/F1NKD2/entry#A0A8V0XYY4-1", "sequence": { "sequence": "MVDITRLTTKYQHDRADQHICTSLLKTKTCSLERALRRTHRFQKWLRAKRLTPDLVQGLSSPMLRCPSQRLLDRIVRRYAEVPDAGSIYMDHLTDQDKLRLLYTLSVNSHPILLQIFPDVEGWPFPRYLGSCGRLVVSASTRPLRDFFRAAPEVAADLALQLLAVLHSMGTNDLNYFFYFTRVDVGTFGVFSNGHLFIRDASTLGIIDKEEGSQPIDGQQEYKDIFSCLTVDCQSAFVSCNSIREKQSLVMVCQELLPKLLRGKFLPPVQEKIDSFLQHCAEGLADDQDVNEAMAKLAQLLKPLRSCDSRFAYRYPDCKYSDKY", "length": 324, "header": "tr|A0A8V0XYY4-1|F1NKD2_CHICK Computationally mapped isoform of Divergent protein kinase domain 2B OS=Gallus gallus OX=9031 GN=CXorf36 PE=3 SV=1 CANONICAL=F1NKD2-1" }, "locus": { "chromosome": "1", "start_pos": 110895248, "end_pos": 110885877, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023375.1", "url": "https://www.ensembl.org/id/ENSGALT00010023375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013506.1", "url": "https://www.ensembl.org/id/ENSGALP00010013506.1" } ] } }, { "isoform_ac": "F1NKD2-1", "url": "https://www.uniprot.org/uniprotkb/F1NKD2/entry#F1NKD2-1", "sequence": { "sequence": "MGRWICCLCSRVADWLMLLLVLARSSNPSAAATASPSAPHVRPSYSFGRTFLGLDKCNACIGTSICKKFFKEEIRFDTWLSSHLKLPPSYLLSYLGNYTDDAQSWRMVDITRLTTKYQHDRADQHICTSLLKTKTCSLERALRRTHRFQKWLRAKRLTPDLVQGLSSPMLRCPSQRLLDRIVRRYAEVPDAGSIYMDHLTDQDKLRLLYTLSVNSHPILLQIFPDVEGWPFPRYLGSCGRLVVSASTRPLRDFFRAAPEVAADLALQLLAVLHSMGTNDLNYFFYFTRVDVGTFGVFSNGHLFIRDASTLGIIDKEEGSQPIDGQQEYKDIFSCLTVDCQSAFVSCNSIREKQSLVMVCQELLPKLLRGKFLPPVQEKIDSFLQHCAEGLADDQDVNEAMAKLAQLLKPLRSCDSRFAYRYPDCKYSDKY", "length": 430, "header": "tr|F1NKD2-1|F1NKD2_CHICK Isoform 1 of Divergent protein kinase domain 2B OS=Gallus gallus OX=9031 GN=CXorf36 PE=3 SV=4 CANONICAL=F1NKD2-1" }, "locus": { "chromosome": "1", "start_pos": 110895248, "end_pos": 110880463, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010023384.1", "url": "https://www.ensembl.org/id/ENSGALT00010023384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010013509.1", "url": "https://www.ensembl.org/id/ENSGALP00010013509.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418555", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418555", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZCG1-1", "protein_name": "Divergent protein kinase domain 2B", "gene_name": "Dipk2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGRPGAAATAFRQRWPAWMLLWVSTLSCSFSLPASLPPSLVPRVRSSYTLGKTFLGLDKCNACIGTSICKKFFKEEIRLDNSLVSHLGLPSQDLLSYAANYSDDSKTWRPVEISRLVSKYQSEISDKRICASASGPKTCSIERILRKTGRFQKWLQAKRLTPDLVQGLPSPFLHCPSQRLLDRVVRRYAEVVDAGSIFMDHFTDRDKLRLLYTLAVNAHPIILQIFPGAEGWPMPKYLGSCGRFLVSTSTRPLQEFYDAPPEQAADIAYQLLGVLESLRSNDLNYFFYFTHVDAGMFGIFDNGHLFIRDASALGIIDKQEASQAADRTGENEDIFSCLVSGCQVQMSSCDTVPEKQNLVLVCQQLLPQLLRGKFPSPVQQEIDSALSLCSKDASTNLEVFGATSLLKNILRSLRTCDPRFAYRYPDCKYNDRF", "length": 435 }, "evidence": [ { "id": "F1NKD2", "url": "https://omabrowser.org/oma/group/F1NKD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C3I9-1", "protein_name": "Divergent protein kinase domain 2B", "gene_name": "Dipk2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESQWRGAAATAFHQHWLARLLLWVSTLSCSFSLPASLPPSLVPRVRSSYTMGKTFLGLDKCNACIGTSICKKFFKEEIRFDNSLASHLGLPPQDLHSYAANYSDDSKTWRPVEISQLVSRYQIEISDRRICASVSAPKTCSIERILQKTGRFQKWLQAKRLTPDLVQGLPSPFLRCPSQRLLDRVVRRYAEVVDAGSIFMDHFTAGDKLRLLYTLAVNAHPIILQIFPGAEGWPMPRYLGSCGRFLVSTSTRPLQEFYDASPEQAADLAYQLLRVLESLRSNDLNYFFYFTHVDAGMFGIFDNGHLFIRDASALGIIDKQEGSQAAARTGENEDIFSCLVSDCQIQLSSCDTVPEKQSLVLVCQQLLPQLLQGKFPSPVQKEIDSALSLCSKDNSTDLEVLGATSWLKDILRSLRTCDPRFAYRYPDCKYNDRF", "length": 435 }, "evidence": [ { "id": "F1NKD2", "url": "https://omabrowser.org/oma/group/F1NKD2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H7Y0-1", "protein_name": "Divergent protein kinase domain 2B", "gene_name": "DIPK2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPQLGPEAAALRPGWLALLLWVSALSCSFSLPASSLSSLVPQVRTSYNFGRTFLGLDKCNACIGTSICKKFFKEEIRSDNWLASHLGLPPDSLLSYPANYSDDSKIWRPVEIFRLVSKYQNEISDRRICASASAPKTCSIERVLRKTERFQKWLQAKRLTPDLVQGLASPLLRCPSQRLLDRVVRRYAEVADAGSIFMDHFTDRDKLRLLYTLAVNSHPILLQIFPGAEGWPLPKYLGSCGRFLVSTSTRPLQEFYDAPPDQAADLAYQLLGVLESLRSNDLNYFFYFTHIDAGMFGVFNNGHLFIRDASAVGVIDKQEGSQEANRAGENKDIFSCLVSGCQAQLPSCESISEKQSLVLVCQKLLPRLLQGRFPSPVQDDIDSILVQCGDSIRPDPEVLGAASQLKDILRPLRTCDSRFAYRYPDCKYNDKF", "length": 433 }, "evidence": [ { "id": "F1NKD2", "url": "https://omabrowser.org/oma/group/F1NKD2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "F1NKD2", "url": "https://www.uniprot.org/uniprotkb/F1NKD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C9A2-1", "uniprot_ac": "E1C9A2", "uniprot_id": "E1C9A2_CHICK", "mass": { "chemical_mass": 14597.0, "monoisotopic_mass": 14597.0 }, "refseq": { "ac": "XP_015140530", "name": "quinone oxidoreductase PIG3 isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140530" }, "gene_names": [ { "name": "TP53I3", "type": "recommended", "evidence": [ { "id": "E1C9A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ] }, { "name": "TP53I3", "type": "synonym", "evidence": [ { "id": "XP_015140530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140530" } ] } ], "protein_names": [ { "name": "Profilin", "type": "recommended", "evidence": [ { "id": "E1C9A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C9A2/entry#names_and_taxonomy" } ] }, { "name": "quinone oxidoreductase PIG3 isoform X9", "type": "synonym", "evidence": [ { "id": "XP_015140530", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140530" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015140530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015140530" } ] }, { "annotation": "Involved in male fertility. Required for manchette development and acrosome biogenesis during spermiogenesis. Binds in vitro to phospholipids, including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Contrary to other profilin family members, does not bind to actin in vitro.", "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2#function" }, { "database": "UniProtKB", "id": "ARBA00059169", "url": "https://www.uniprot.org/uniprotkb/ARBA00059169#function" }, { "database": "UniProtKB", "id": "A0A8V0Y7E9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7E9#function" }, { "database": "UniProtKB", "id": "A0A8V0XZ07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZ07#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TP53I3", "url": "https://www.uniprot.org/uniprotkb/E1C9A2", "locus": { "chromosome": "3", "start_pos": 104037023, "end_pos": 104041205, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011902", "url": "https://www.ensembl.org/id/ENSGALG00010011902" } ] } } ], "crossref": [ { "id": "E1C9A2", "url": "https://alphafold.ebi.ac.uk/entry/E1C9A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019866", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019866", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00148", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00148", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421977", "url": "https://www.ncbi.nlm.nih.gov/gene/421977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107053160", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053160", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XZ07", "url": "https://www.orthodb.org/?gene=A0A8V0XZ07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y7E9", "url": "https://www.orthodb.org/?gene=A0A8V0Y7E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C9A2", "url": "https://www.orthodb.org/?gene=E1C9A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11604", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11604", "database": "PANTHER", "categories": [ "Protein 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"categories": [ "Protein" ] }, { "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C9A2-1", "url": "https://www.uniprot.org/uniprotkb/E1C9A2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQLQALLKESLIRTKHVENAAAIGINEREVCASTSGFYVPPENAINLIYAFYKNLLQVRKEGLYFRQKHYECVRADEHSIYLKNAEGGLIVVKTNALILIATYRVGMYPSVCVEAVEKLADYLREKGS", "length": 129, "header": "tr|E1C9A2-1|E1C9A2_CHICK Isoform 1 of Profilin OS=Gallus gallus OX=9031 GN=TP53I3 PE=3 SV=3 CANONICAL=E1C9A2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XZ07-1", "url": "https://www.uniprot.org/uniprotkb/E1C9A2/entry#A0A8V0XZ07-1", "sequence": { "sequence": "MIQLQALLKESLIRTKHVENAAAIGINEREVCASTSGFYVPPENAINLIYAFYKNLLQVRKEGLYFRQKHYECVRADEHSIYLKNAEGGLIVVKTNALILIATYRVGMYPSVCVEAVEKLGPGFRQF", "length": 127, "header": "tr|A0A8V0XZ07-1|E1C9A2_CHICK Computationally mapped isoform of Profilin OS=Gallus gallus OX=9031 GN=TP53I3 PE=3 SV=1 CANONICAL=E1C9A2-1" }, "locus": { "chromosome": "3", "start_pos": 104046756, "end_pos": 104044492, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020620.1", "url": "https://www.ensembl.org/id/ENSGALT00010020620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011936.1", "url": "https://www.ensembl.org/id/ENSGALP00010011936.1" } ] } }, { "isoform_ac": "A0A8V0Y7E9-1", "url": "https://www.uniprot.org/uniprotkb/E1C9A2/entry#A0A8V0Y7E9-1", "sequence": { "sequence": "MVLELLSSPRRTGFQYNRGRTFIHLYLLTERMIQLQALLKESLIRTKHVENAAAIGINEREVCASTSGFYVPPENAINLIYAFYKNLLQVRKEGLYFRQKHYECVRADEHSIYLKNAEGGLIVVKTNALILIATYRVGMYPSVCVEAVEKLADYLREKGS", "length": 160, "header": "tr|A0A8V0Y7E9-1|E1C9A2_CHICK Computationally mapped isoform of Profilin OS=Gallus gallus OX=9031 GN=TP53I3 PE=3 SV=1 CANONICAL=E1C9A2-1" }, "locus": { "chromosome": "3", "start_pos": 104046849, "end_pos": 104044161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107053160", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053160", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ], "pmid": "" }, { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": 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"database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ], "pmid": "" }, { "name": "manchette assembly", "id": "GO:1905198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905198", "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ], "pmid": "" }, { "name": "sperm flagellum assembly", "id": "GO:0120316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120316", "evidence": [ { "database": "UniProtKB", "id": "E1C9A2", "url": "https://www.uniprot.org/uniprotkb/E1C9A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1H9-1", "uniprot_ac": "E1C1H9", "uniprot_id": "E1C1H9_CHICK", "mass": { "chemical_mass": 60022.0, "monoisotopic_mass": 60022.0 }, "refseq": { "ac": "NP_001384321", "name": "inactive phospholipase D5 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384321" }, "gene_names": [ { "name": "PLD5", "type": "recommended", "evidence": [ { "id": "E1C1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1H9" } ] }, { "name": "PLD5", "type": "synonym", "evidence": [ { "id": "NP_001384321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384321" } ] } ], "protein_names": [ { "name": "Phospholipase D family member 5", "type": "synonym", "evidence": [ { "id": "E1C1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1H9/entry#names_and_taxonomy" } ] }, { "name": "inactive phospholipase D5 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001384321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384321" } ] }, { "name": "inactive phospholipase D5", "type": "synonym", "evidence": [ { "id": "NP_001384321", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384321" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.261565.1, SRR13267661.10615.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On Nov 10, 2021 this sequence version replaced XP_015139436.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001384321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384321" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1H9", "url": "https://www.uniprot.org/uniprotkb/E1C1H9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLD5", "url": "https://www.uniprot.org/uniprotkb/E1C1H9", "locus": { "chromosome": "3", "start_pos": 35327041, "end_pos": 35060441, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008383", "url": "https://www.ensembl.org/id/ENSGALG00010008383" } ] } } ], "crossref": [ { "id": "E1C1H9", "url": "https://alphafold.ebi.ac.uk/entry/E1C1H9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010737", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010737", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09149", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09149", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421501", "url": "https://www.ncbi.nlm.nih.gov/gene/421501", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032803", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032803", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ETRYWPY", "url": "https://omabrowser.org/oma/group/ETRYWPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C1H9", "url": "https://www.orthodb.org/?gene=E1C1H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10185:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10185:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384321", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y007", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y007", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y007-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y007-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y2G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1H9", "url": "https://www.uniprot.org/uniprotkb/E1C1H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1H9-1", "url": "https://www.uniprot.org/uniprotkb/E1C1H9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVRHDWLSSSPHEGFEQMRLKSRPREPSPSLTRVGANFYSTVKQQDYSASVWLRRKDKLEHSQQRCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNNCRVALVENIPEGINYSDSAPSHLSLFQGWMNLLNMAEKSVDIVSSQWDLNHSHPSACQGQRLFEKLLELASRNIEIKLVSDILPVESKVLNDLKSKGAEVLYMNMSAYNEGRLQSSFWIVDKQHVYIGSASLDWRSLGQMKELGVIVYNCSCLVLDLQRIFALYSSLKYKNKIPPSWSKRLYGVYDTQNKLTLQLNETKSEAFVSNSPKLFCPKDRVLDIEAIYNVIDDAKQFVYIAVMDYLPIVIDTNAKRYWPFLDGKIREALVLRSIKVRLLISFSRDTDPLTFNFVSSLKAICTEVPSCSLKVKFFDLEEESACFLKDQKNASLPKLNRNKYMVTDGAAYIGNFDWVGNAFTQNAGAGLVINQADAGNSTSIIKQLKAVFERDWYSHYAKSLQPTKMPNCFNHKLSKATSNKTAMSNVN", "length": 529, "header": "tr|E1C1H9-1|E1C1H9_CHICK Isoform 1 of Phospholipase D family member 5 OS=Gallus gallus OX=9031 GN=PLD5 PE=3 SV=2 CANONICAL=E1C1H9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y007-1", "url": "https://www.uniprot.org/uniprotkb/E1C1H9/entry#A0A8V0Y007-1", "sequence": { "sequence": "MQENLILEVTHKIWGGRSAESPSKQESITEVWQCSCGQADVMLSHTLSQQRCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNNCRVALVENIPEGINYSDSAPSHLSLFQGWMNLLNMAEKSVDIVSSQWDLNHSHPSACQGQRLFEKLLELASRNIEIKLVSDILPVESKVLNDLKSKGAEVLYMNMSAYNEGRLQSSFWIVDKQHVYIGSASLDWRSLGQMKELGVIVYNCSCLVLDLQRIFALYSSLKYKNKIPPSWSKRLYGVYDTQNKLTLQLNETKSEAFVSNSPKLFCPKDRVLDIEAIYNVIDDAKQFVYIAVMDYLPIVIDTNAKRYWPFLDGKIREALVLRSIKVRLLISFSRDTDPLTFNFVSSLKAICTEVPSCSLKVKFFDLEEESACFLKDQKNASLPKLNRNKYMVTDGAAYIGNFDWVGNAFTQNAGAGLVINQADAGNSTSIIKQLKAVFERDWYSHYAKSLQPTKMPNCFNHKLSKATSNKTAMSNVN", "length": 514, "header": "tr|A0A8V0Y007-1|E1C1H9_CHICK Computationally mapped isoform of Phospholipase D family member 5 OS=Gallus gallus OX=9031 GN=PLD5 PE=3 SV=1 CANONICAL=E1C1H9-1" }, "locus": { "chromosome": "3", "start_pos": 35325050, "end_pos": 35060494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020063.1", "url": "https://www.ensembl.org/id/ENSGALT00010020063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011611.1", "url": "https://www.ensembl.org/id/ENSGALP00010011611.1" } ] } }, { "isoform_ac": "A0A8V0Y2G1-1", "url": "https://www.uniprot.org/uniprotkb/E1C1H9/entry#A0A8V0Y2G1-1", "sequence": { "sequence": "MKMDSRRRTVKITVDRRSPIFIYTRVALVENIPEGINYSDSAPSHLSLFQGWMNLLNMAEKSVDIVSSQWDLNHSHPSACQGQRLFEKLLELASRNIEIKLVSDILPVESKVLNDLKSKGAEVLYMNMSAYNEGRLQSSFWIVDKQHVYIGSASLDWRSLGQMKELGVIVYNCSCLVLDLQRIFALYSSLKYKNKIPPSWSKRLYGVYDTQNKLTLQLNETKSEAFVSNSPKLFCPKDRVLDIEAIYNVIDDAKQFVYIAVMDYLPIVIDTNAKRYWPFLDGKIREALVLRSIKVRLLISFSRDTDPLTFNFVSSLKAICTEVPSCSLKVKFFDLEEESACFLKDQKNASLPKLNRNKYMVTDGAAYIGNFDWVGNAFTQNAGAGLVINQADAGNSTSIIKQLKAVFERDWYSHYAKSLQPTKMPNCFNHKLSKATSNKTAMSNVN", "length": 446, "header": "tr|A0A8V0Y2G1-1|E1C1H9_CHICK Computationally mapped isoform of Phospholipase D family member 5 OS=Gallus gallus OX=9031 GN=PLD5 PE=3 SV=1 CANONICAL=E1C1H9-1" }, "locus": { "chromosome": "3", "start_pos": 35325050, "end_pos": 35226047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020059.1", "url": "https://www.ensembl.org/id/ENSGALT00010020059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011607.1", "url": "https://www.ensembl.org/id/ENSGALP00010011607.1" } ] } }, { "isoform_ac": "E1C1H9-1", "url": "https://www.uniprot.org/uniprotkb/E1C1H9/entry#E1C1H9-1", "sequence": { "sequence": "MEVRHDWLSSSPHEGFEQMRLKSRPREPSPSLTRVGANFYSTVKQQDYSASVWLRRKDKLEHSQQRCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNNCRVALVENIPEGINYSDSAPSHLSLFQGWMNLLNMAEKSVDIVSSQWDLNHSHPSACQGQRLFEKLLELASRNIEIKLVSDILPVESKVLNDLKSKGAEVLYMNMSAYNEGRLQSSFWIVDKQHVYIGSASLDWRSLGQMKELGVIVYNCSCLVLDLQRIFALYSSLKYKNKIPPSWSKRLYGVYDTQNKLTLQLNETKSEAFVSNSPKLFCPKDRVLDIEAIYNVIDDAKQFVYIAVMDYLPIVIDTNAKRYWPFLDGKIREALVLRSIKVRLLISFSRDTDPLTFNFVSSLKAICTEVPSCSLKVKFFDLEEESACFLKDQKNASLPKLNRNKYMVTDGAAYIGNFDWVGNAFTQNAGAGLVINQADAGNSTSIIKQLKAVFERDWYSHYAKSLQPTKMPNCFNHKLSKATSNKTAMSNVN", "length": 529, "header": "tr|E1C1H9-1|E1C1H9_CHICK Isoform 1 of Phospholipase D family member 5 OS=Gallus gallus OX=9031 GN=PLD5 PE=3 SV=2 CANONICAL=E1C1H9-1" }, "locus": { "chromosome": "3", "start_pos": 35325050, "end_pos": 35162030, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010020061.1", "url": "https://www.ensembl.org/id/ENSGALT00010020061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011609.1", "url": "https://www.ensembl.org/id/ENSGALP00010011609.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1BJN9-1", "protein_name": "Phospholipase D family member 5", "gene_name": "PLD5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSENAPFHLSLFQGWMNLLSMAKKSVDIVSSHWDLNHSHPSACQGQRLFEKLLQLTSQSIEIKLVSDVTADSKVLEALKSKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACIRKEQRNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRNNTSIIKQLKDVFERDWYSPYARTLQPTKQPNCSSLFRLRLPSNKTAMYNASGKDP", "length": 533 }, "evidence": [ { "id": "E1C1H9", "url": "https://omabrowser.org/oma/group/E1C1H9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1MA92-1", "protein_name": "Phospholipase D family, member 5", "gene_name": "Pld5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAVLVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSEDAPFHLPLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSACQGQRLFEKLLQLTSQNIEVKLVSDVTADSKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVTDYLPISSTSTKRTYWPDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRDNRSIIKQLKDVFERDWYSPYAKSIQPTKQPNCSNLSKLKTPSNQPAIYNTTGREPLSV", "length": 536 }, "evidence": [ { "id": "E1C1H9", "url": "https://omabrowser.org/oma/group/E1C1H9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S8N8-1", "protein_name": "Phospholipase D family member 5", "gene_name": "PLD5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEIRQHEWLSASPHDGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVVFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDLNHSHPSACQGQRLFEKLLQLTSESVEIKLVSDVTADSKVLEALKSKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVTDYLPISSTSTKRTYWPDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACVTTKEQKNHTFPKLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRNNTSIIKQLKDVFERDWYSPYARTLQPTKQPNCSGLFKLRPPSNKTATYNASGKDPSSVSSE", "length": 540 }, "evidence": [ { "id": "E1C1H9", "url": "https://omabrowser.org/oma/group/E1C1H9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UNN8-1", "protein_name": "Inactive phospholipase D5", "gene_name": "Pld5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAVLVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSEDAPFHLPLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPAACQGQRLFEKLLQLTSQNIEVKLVSDVTADSKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVTDYLPISSTSSKRTYWPDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRDNRSIIKQLKDVFERDWYSPYAKSIQPTKQPNCSSLSKLKSPSKQPAMANATGREPLSV", "length": 536 }, "evidence": [ { "id": "E1C1H9", "url": "https://omabrowser.org/oma/group/E1C1H9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N7P1-1", "protein_name": "Inactive phospholipase D5", "gene_name": "PLD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSSLFKLKPLSNKTATDDTGGKDPRNV", "length": 536 }, "evidence": [ { "id": "E1C1H9", "url": "https://omabrowser.org/oma/group/E1C1H9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "E1C1H9", "url": "https://www.uniprot.org/uniprotkb/E1C1H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1H9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 529, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1H9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1H9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 521, "end_pos": 523 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NGI7-1", "uniprot_ac": "F1NGI7", "uniprot_id": "F1NGI7_CHICK", "mass": { "chemical_mass": 64642.0, "monoisotopic_mass": 64642.0 }, "refseq": { "ac": "NP_001186389", "name": "copine-8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389" }, "gene_names": [ { "name": "CPNE8", "type": "recommended", "evidence": [ { "id": "F1NGI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGI7" } ] }, { "name": "CPNE5", "type": "synonym", "evidence": [ { "id": "NP_001186389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389" } ] }, { "name": "CPNE8", "type": "synonym", "evidence": [ { "id": "NP_001186389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389" } ] }, { "name": "copine-8", "type": "synonym", "evidence": [ { "id": "NP_001186389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389" } ] } ], "protein_names": [ { "name": "Copine-8", "type": "recommended", "evidence": [ { "id": "F1NGI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGI7/entry#names_and_taxonomy" } ] }, { "name": "Copine VIII", "type": "synonym", "evidence": [ { "id": "F1NGI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NGI7/entry#names_and_taxonomy" } ] }, { "name": "copine VIII", "type": "synonym", "evidence": [ { "id": "NP_001186389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389" } ] }, { "name": "copine-8", "type": "synonym", "evidence": [ { "id": "NP_001186389", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.157798.1, ERR2365565.146743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000012.1. On Dec 9, 2010 this sequence version replaced XP_001231389.1. Sequence Note: This RefSeq record was created from transcripts from different strains and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186389", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389" } ] }, { "annotation": "Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.", "evidence": [ { "database": "UniProtKB", "id": "F1NGI7", "url": "https://www.uniprot.org/uniprotkb/F1NGI7#function" }, { "database": "UniProtKB", "id": "ARBA00057254", "url": "https://www.uniprot.org/uniprotkb/ARBA00057254#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NGI7", "url": "https://www.uniprot.org/uniprotkb/F1NGI7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPNE8", "url": "https://www.uniprot.org/uniprotkb/F1NGI7", "locus": { "chromosome": "1", "start_pos": 15788625, "end_pos": 15692490, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008087", "url": "https://www.ensembl.org/id/ENSGALG00010008087" } ] } } ], "crossref": [ { "id": "F1NGI7", "url": "https://alphafold.ebi.ac.uk/entry/F1NGI7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007025", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007025", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417690", "url": "https://www.ncbi.nlm.nih.gov/gene/417690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417690", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417690", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMILVYF", "url": "https://omabrowser.org/oma/group/LMILVYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y0G3", "url": "https://www.orthodb.org/?gene=A0A8V0Y0G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y414", "url": "https://www.orthodb.org/?gene=A0A8V0Y414", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y420", "url": "https://www.orthodb.org/?gene=A0A8V0Y420", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NGI7", "url": "https://www.orthodb.org/?gene=F1NGI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186389", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186389", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y0G3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y0G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y414", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y414", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y414-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y414-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y420", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y420", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y420-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y420-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGI7", "url": "https://www.uniprot.org/uniprotkb/F1NGI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NGI7-1", "url": "https://www.uniprot.org/uniprotkb/F1NGI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGLEKPPGQQKLGRSGGFPNMASVGDFNVLSSSIPATKVELSVSCRNLLDRDTFSKSDPICVLYTQAIGNKEWREFGRTEVIDNTLNPDFVRKFIMDYFFEERENLRFDFYDVDSKSPNLSKHDFLGQMFCTLGEIVGSQGSRLEKPIAGIPGKKCGTVIVTAEELGCCRDSVLMQFCANKLDKKDFFGKSDPFLVFHRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVINPKKKGKKKKYVNSGTVTLLSFLIETEVSFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKMFPALGFGARLPPDGRVSHEFALNGNPQNPYCHGIDGVMEAYYRSLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMEELDGDVVRISSRGKFAERDIVQFVPFRDYIDRSGNHVLSMARLAKDVLAEIPDQFLSYMRVRGIKPSPAPPPYTPPIHVLQTQI", "length": 578, "header": "tr|F1NGI7-1|F1NGI7_CHICK Isoform 1 of Copine-8 OS=Gallus gallus OX=9031 GN=CPNE8 PE=3 SV=2 CANONICAL=F1NGI7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y0G3-1", "url": "https://www.uniprot.org/uniprotkb/F1NGI7/entry#A0A8V0Y0G3-1", "sequence": { "sequence": "MFGLEKPPGQQKLGRSGGFPNMASVGDFNVLSSSIPATKVELSVSCRNLLDRDTFSKSDPICVLYTQAIGNKEWRERHSWEKMWYCHCNSRGTGLLSSKCVFIAF", "length": 105, "header": "tr|A0A8V0Y0G3-1|F1NGI7_CHICK Computationally mapped isoform of Copine-8 OS=Gallus gallus OX=9031 GN=CPNE8 PE=3 SV=1 CANONICAL=F1NGI7-1" }, "locus": { "chromosome": "1", "start_pos": 15740904, "end_pos": 15692626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019289.1", "url": "https://www.ensembl.org/id/ENSGALT00010019289.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010837.1", "url": "https://www.ensembl.org/id/ENSGALP00010010837.1" } ] } }, { "isoform_ac": "A0A8V0Y414-1", "url": "https://www.uniprot.org/uniprotkb/F1NGI7/entry#A0A8V0Y414-1", "sequence": { "sequence": "MLCLEDVSASVEYFIVPEFGRTEVIDNTLNPDFVRKFIMDYFFEERENLRFDFYDVDSKSPNLSKHDFLGQMFCTLGEIVGSQGSRLEKPIAGIPGKKCGTVIVTAEELGCCRDSVLMQFCANKLDKKDFFGKSDPFLVFHRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVINPKKKGKKKKYVNSGTVTLLSFLIETEVSFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKMFPALGFGARLPPDGRVSHEFALNGNPQNPYCHGIDGVMEAYYRSLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMEELDGDVVRISSRGKFAERDIVQFVPFRDYIDRSGNHVLSMARLAKDVLAEIPDQFLSYMRVRGIKPSPAPPPYTPPIHVLQTQI", "length": 520, "header": "tr|A0A8V0Y414-1|F1NGI7_CHICK Computationally mapped isoform of Copine-8 OS=Gallus gallus OX=9031 GN=CPNE8 PE=3 SV=1 CANONICAL=F1NGI7-1" }, "locus": { "chromosome": "1", "start_pos": 15786842, "end_pos": 15724102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019292.1", "url": "https://www.ensembl.org/id/ENSGALT00010019292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010840.1", "url": "https://www.ensembl.org/id/ENSGALP00010010840.1" } ] } }, { "isoform_ac": "A0A8V0Y420-1", "url": "https://www.uniprot.org/uniprotkb/F1NGI7/entry#A0A8V0Y420-1", "sequence": { "sequence": "MFGLEKPPGQQKLGRSGGFPNMASVGDFNVLSSSIPATKVELSVSCRNLLDRDTFSKSDPICVLYTQAIGNKEWREFGRTEVIDNTLNPDFVRKFIMDYFFEERENLRFDFYDVDSKSPNLSKHDFLGQMFCTLGEIVGSQGSRLEKPIAGIPGKKCGTVIVTAEELGCCRDSVLMQFCANKLDKKDFFGKSDPFLVFHRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTQINFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKMFPALGFGARLPPDGRVSHEFALNGNPQNPYCHGIDGVMEAYYRSLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMEELDGDVVRISSRGKFAERDIVQFVPFRDYIDRSGNHVLSMARLAKDVLAEIPDQFLSYMRVRGIKPSPAPPPYTPPIHVLQTQI", "length": 500, "header": "tr|A0A8V0Y420-1|F1NGI7_CHICK Computationally mapped isoform of Copine-8 OS=Gallus gallus OX=9031 GN=CPNE8 PE=3 SV=1 CANONICAL=F1NGI7-1" }, "locus": { "chromosome": "1", "start_pos": 15786842, "end_pos": 15692626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019297.1", "url": "https://www.ensembl.org/id/ENSGALT00010019297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010845.1", "url": "https://www.ensembl.org/id/ENSGALP00010010845.1" } ] } }, { "isoform_ac": "F1NGI7-1", "url": "https://www.uniprot.org/uniprotkb/F1NGI7/entry#F1NGI7-1", "sequence": { "sequence": "MFGLEKPPGQQKLGRSGGFPNMASVGDFNVLSSSIPATKVELSVSCRNLLDRDTFSKSDPICVLYTQAIGNKEWREFGRTEVIDNTLNPDFVRKFIMDYFFEERENLRFDFYDVDSKSPNLSKHDFLGQMFCTLGEIVGSQGSRLEKPIAGIPGKKCGTVIVTAEELGCCRDSVLMQFCANKLDKKDFFGKSDPFLVFHRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVINPKKKGKKKKYVNSGTVTLLSFLIETEVSFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKMFPALGFGARLPPDGRVSHEFALNGNPQNPYCHGIDGVMEAYYRSLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMEELDGDVVRISSRGKFAERDIVQFVPFRDYIDRSGNHVLSMARLAKDVLAEIPDQFLSYMRVRGIKPSPAPPPYTPPIHVLQTQI", "length": 578, "header": "tr|F1NGI7-1|F1NGI7_CHICK Isoform 1 of Copine-8 OS=Gallus gallus OX=9031 GN=CPNE8 PE=3 SV=2 CANONICAL=F1NGI7-1" }, "locus": { "chromosome": "1", "start_pos": 15786842, "end_pos": 15692626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019295.1", "url": "https://www.ensembl.org/id/ENSGALT00010019295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010843.1", "url": "https://www.ensembl.org/id/ENSGALP00010010843.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417690", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417690", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "B5DEX3-1", "protein_name": "Copine-8", "gene_name": "Cpne8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWARDKCSAPPLEMDSRYTSATGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 577 }, "evidence": [ { "id": "F1NGI7", "url": "https://omabrowser.org/oma/group/F1NGI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LB11-1", "protein_name": "Copine-8", "gene_name": "CPNE8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWVPDKSTEPSLKMDSRYTSTAGLGDLNQLSATIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVINPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 577 }, "evidence": [ { "id": "F1NGI7", "url": "https://omabrowser.org/oma/group/F1NGI7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5S1W2-1", "protein_name": "Protein BONZAI 2", "gene_name": "BON2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGSCWSDGSYAGGGMVGVGGGANSSAATPNDAVDYYLKSRGYNGLFSQIELSFSASNLRDRDVISKSDAMVVVYTKGRDGTLAELFRSEVVLNSLNPKWIKNFTIGYQFEIVQTLLFRVYDIDTQFQNSKEELLKLDEQQFLGEATCTLSEVVTKSNRTIALELMRKEGVAAQTQPQHNGKLIVHAEESLASKTNTEIVFRGLNLESKDTFSKSDPFLVISKIVEHGTPIPVSKTEVLKNDPNPLWKPVSLSVQQVGSKDSPLVIECLDFNGNGNHDLIGKVQKSLSDLEKLHLAGQGINLALPTGVGHKHEDRVLKSQLFVDKFTETVQHTFLEYLASGFELNFMVAIDFTASNGNPRLPDSLHYIDPTGRLNAYQRAIVEVGEVLQFYDSDKRFPAWGFGARPIDIPVSHCFNLNGSSTYCEVDGIQGIMNAYNGALFNVSFAGPTLFGPVINAAATIASDSLAQSAKKYYVLLIITDGVITDLQETRDSIVSASDLPLSILIVGVGGADYKEMEVLDGDKGEKLESSSGRIASRDIVQFVALRDIQYGEVSVVEALLAELPTQFLTYMRNRNITPTTTTPSST", "length": 586 }, "evidence": [ { "id": "F1NGI7", "url": "https://omabrowser.org/oma/group/F1NGI7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q86YQ8-1", "protein_name": "Copine-8", "gene_name": "CPNE8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 564 }, "evidence": [ { "id": "F1NGI7", "url": "https://omabrowser.org/oma/group/F1NGI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DC53-1", "protein_name": "Copine-8", "gene_name": "Cpne8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWARDKCSVPQLEMDSRYTSATGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 577 }, "evidence": [ { "id": "F1NGI7", "url": "https://omabrowser.org/oma/group/F1NGI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "F1NGI7", "url": "https://www.uniprot.org/uniprotkb/F1NGI7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "F1NGI7", "url": "https://www.uniprot.org/uniprotkb/F1NGI7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NGI7", "url": "https://www.uniprot.org/uniprotkb/F1NGI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "F1NGI7", "url": "https://www.uniprot.org/uniprotkb/F1NGI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NGI7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 578, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NGI7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NGI7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 472, "end_pos": 474 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NEI0-1", "uniprot_ac": "F1NEI0", "uniprot_id": "F1NEI0_CHICK", "mass": { "chemical_mass": 66029.0, "monoisotopic_mass": 66029.0 }, "refseq": { "ac": "XP_015133137", "name": "ectoderm-neural cortex protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133137" }, "gene_names": [ { "name": "ENC1", "type": "recommended", "evidence": [ { "id": "F1NEI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ] }, { "name": "ENC1", "type": "synonym", "evidence": [ { "id": "XP_015133137", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133137" } ] } ], "protein_names": [ { "name": "Ectodermal-neural cortex 1", "type": "synonym", "evidence": [ { "id": "F1NEI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEI0/entry#names_and_taxonomy" } ] }, { "name": "ectoderm-neural cortex protein 1", "type": "synonym", "evidence": [ { "id": "XP_015133137", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133137" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133137" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ENC1", "url": "https://www.uniprot.org/uniprotkb/F1NEI0", "locus": { "chromosome": "Z", "start_pos": 24837186, "end_pos": 24823886, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010905", "url": "https://www.ensembl.org/id/ENSGALG00010010905" } ] } } ], "crossref": [ { "id": "ENSGALG00000014930", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014930", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18267", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18267", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18515", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18515", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427203", "url": "https://www.ncbi.nlm.nih.gov/gene/427203", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427203", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427203", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMSVSMH", "url": "https://omabrowser.org/oma/group/KMSVSMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y297", "url": "https://www.orthodb.org/?gene=A0A8V0Y297", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8I8", "url": "https://www.orthodb.org/?gene=A0A8V0Y8I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NEI0", "url": "https://www.orthodb.org/?gene=F1NEI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF496", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF496", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015133137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133137", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y297", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y297", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y297-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y297-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NEI0-1", "url": "https://www.uniprot.org/uniprotkb/F1NEI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVSMHENRKSRASTGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRSFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFHNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQSISKSEDFLQLPKDMVVQLLSSEELETEDERLVYESAINWVNYDLSKRHCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEESIRCKLKILQNDGVVTSLCARPRKTGHSLFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPVTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 589, "header": "tr|F1NEI0-1|F1NEI0_CHICK Isoform 1 of Ectodermal-neural cortex 1 OS=Gallus gallus OX=9031 GN=ENC1 PE=4 SV=2 CANONICAL=F1NEI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y297-1", "url": "https://www.uniprot.org/uniprotkb/F1NEI0/entry#A0A8V0Y297-1", "sequence": { "sequence": "MALKKVWKKMSVSMHENRKSRASTGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRSFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFHNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQSISKSEDFLQLPKDMVVQLLSSEELETEDERLVYESAINWVNYDLSKRHCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEESIRCKLKILQNDGVVTSLCARPRKTGHSLFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPVTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 598, "header": "tr|A0A8V0Y297-1|F1NEI0_CHICK Computationally mapped isoform of Ectodermal-neural cortex 1 OS=Gallus gallus OX=9031 GN=ENC1 PE=4 SV=1 CANONICAL=F1NEI0-1" }, "locus": { "chromosome": "Z", "start_pos": 24830716, "end_pos": 24826554, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026080.1", "url": "https://www.ensembl.org/id/ENSGALT00010026080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014715.1", "url": "https://www.ensembl.org/id/ENSGALP00010014715.1" } ] } }, { "isoform_ac": "A0A8V0Y8I8-1", "url": "https://www.uniprot.org/uniprotkb/F1NEI0/entry#A0A8V0Y8I8-1", "sequence": { "sequence": "MSFIPFNILAWFWTELIVRSCKKVWKKMSVSMHENRKSRASTGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRSFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFHNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQSISKSEDFLQLPKDMVVQLLSSEELETEDERLVYESAINWVNYDLSKRHCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEESIRCKLKILQNDGVVTSLCARPRKTGHSLFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPVTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 616, "header": "tr|A0A8V0Y8I8-1|F1NEI0_CHICK Computationally mapped isoform of Ectodermal-neural cortex 1 OS=Gallus gallus OX=9031 GN=ENC1 PE=4 SV=1 CANONICAL=F1NEI0-1" }, "locus": { "chromosome": "Z", "start_pos": 24830716, "end_pos": 24825518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026082.1", "url": "https://www.ensembl.org/id/ENSGALT00010026082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014717.1", "url": "https://www.ensembl.org/id/ENSGALP00010014717.1" } ] } }, { "isoform_ac": "F1NEI0-1", "url": "https://www.uniprot.org/uniprotkb/F1NEI0/entry#F1NEI0-1", "sequence": { "sequence": "MSVSMHENRKSRASTGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRSFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFHNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQSISKSEDFLQLPKDMVVQLLSSEELETEDERLVYESAINWVNYDLSKRHCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEESIRCKLKILQNDGVVTSLCARPRKTGHSLFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPVTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 589, "header": "tr|F1NEI0-1|F1NEI0_CHICK Isoform 1 of Ectodermal-neural cortex 1 OS=Gallus gallus OX=9031 GN=ENC1 PE=4 SV=2 CANONICAL=F1NEI0-1" }, "locus": { "chromosome": "Z", "start_pos": 24830716, "end_pos": 24828950, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026101.1", "url": "https://www.ensembl.org/id/ENSGALT00010026101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014729.1", "url": "https://www.ensembl.org/id/ENSGALP00010014729.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427203", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427203", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MK88-1", "protein_name": "Ectodermal-neural cortex 1", "gene_name": "ENC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAINWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEHYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDAWNSITTVPYSLIPTAFVSTWKHLPS", "length": 589 }, "evidence": [ { "id": "F1NEI0", "url": "https://omabrowser.org/oma/group/F1NEI0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1QKP6-1", "protein_name": "Ectoderm-neural cortex protein 1", "gene_name": "enc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKMSVCVHENRKSRASTGSMNIFLFHKSSYADSVLMHLNALRQQRLFTDVLLHAGSRSFPCHRAVLAACSRYFEAMFSGGLRESQDSEVDFRDSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPSNCLGMLLLSDAHQCTQLFQLSWSMCLSNFPAICKTEEFLQLPKDMLVQLLAHEELETEDERLVYESALNWVNYDLERRHCHLPELLRTVRLALLPAIFLMENVSTEELIIAQAKSKELVDEAIRCKLRILQNDGVVNSPCARPRKTSHALFLLGGPTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYVTGGRGSENGVSKDVWVYDTLHEEWSKAAPMLIARFGHGSAELRHCLYVVGGHTAATGCLPASPSVSLKQVEQFDPVANKWSMVAPLREGVSNAAVVSVKLKLFAFGGTSVAHDKLPKVQCYDPSENRWTVPASCPQPWRYTAAAVLGNQIFVMGGDTEFSACSAYKFSSETYQWTKVGDVTAKRMSCQAVASGNKLYVVGGYFGTQRCKTLDCYDPTLDAWNSITTVPYSLIPTAFVSTWKHLPA", "length": 591 }, "evidence": [ { "id": "F1NEI0", "url": "https://omabrowser.org/oma/group/F1NEI0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HUS3-1", "protein_name": "Ectoderm-neural cortex protein 1", "gene_name": "Enc1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEHYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 589 }, "evidence": [ { "id": "F1NEI0", "url": "https://omabrowser.org/oma/group/F1NEI0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O14682-1", "protein_name": "Ectoderm-neural cortex protein 1", "gene_name": "ENC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAINWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEHYDPTINKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 589 }, "evidence": [ { "id": "F1NEI0", "url": "https://omabrowser.org/oma/group/F1NEI0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35709-1", "protein_name": "Ectoderm-neural cortex protein 1", "gene_name": "Enc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWSVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 589 }, "evidence": [ { "id": "F1NEI0", "url": "https://omabrowser.org/oma/group/F1NEI0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6DKY8-1", "protein_name": "Ectodermal-neural cortex 1", "gene_name": "Enc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVSVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS", "length": 589 }, "evidence": [ { "id": "F1NEI0", "url": "https://omabrowser.org/oma/group/F1NEI0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" }, { "name": "negative regulation of translation", "id": "GO:0017148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017148", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" }, { "name": "proteasomal ubiquitin-independent protein catabolic process", "id": "GO:0010499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010499", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "F1NEI0", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NEI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NEI0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 114, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1B5-1", "uniprot_ac": "E1C1B5", "uniprot_id": "E1C1B5_CHICK", "mass": { "chemical_mass": 103689.0, "monoisotopic_mass": 103689.0 }, "refseq": { "ac": "XP_004943180", "name": "zinc finger and BTB domain-containing protein 41", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943180" }, "gene_names": [ { "name": "ZBTB41", "type": "recommended", "evidence": [ { "id": "E1C1B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ] }, { "name": "ZBTB41", "type": "synonym", "evidence": [ { "id": "XP_004943180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943180" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 41", "type": "recommended", "evidence": [ { "id": "E1C1B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1B5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 41", "type": "synonym", "evidence": [ { "id": "XP_004943180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943180" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943180" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB41", "url": "https://www.uniprot.org/uniprotkb/E1C1B5", "locus": { "chromosome": "8", "start_pos": 2608347, "end_pos": 2593530, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010334", "url": "https://www.ensembl.org/id/ENSGALG00010010334" } ] } } ], "crossref": [ { "id": "E1C1B5", "url": "https://alphafold.ebi.ac.uk/entry/E1C1B5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002305", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002305", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18226", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424353", "url": "https://www.ncbi.nlm.nih.gov/gene/424353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424353", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVEKASF", "url": "https://omabrowser.org/oma/group/MVEKASF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y6J7", "url": "https://www.orthodb.org/?gene=A0A8V0Y6J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1B5", "url": "https://www.orthodb.org/?gene=E1C1B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943180", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6J7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y6J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1B5-1", "url": "https://www.uniprot.org/uniprotkb/E1C1B5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKRRRLAANVNEKVHLGREKVASDQILVVDCAQEIVSKPAEIAPADQLESAPELSPSSEQRKLLSSLQYNKNLLKYLNDDRQKRPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKNEIPLVLEAAKFLDIIDAVKLLNNESVSSIQSDVVTDTPTPVETLNELTGKLLNSHQCTFCGRSFCYKKSLENHLAKAHRSLSLERKHGLKMVEKAGFSTRRSTRNRKCPVKFDDSDSESDDASDSNLEKVNSDKEPSDRSEFEDSGSECNADEEGQEEEMSGEDSDTEEQSEKEHDTEEGSEVADSVGSIPEGLAPVIIQSSNKKLLQCPKCDKKFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSSDTDFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENVQEFLSIKKTKSEGWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECEECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCEVCKKVFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHMVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGTKAAEEALTSSSEEKLVSLPVPYTSDDKVYQTEAKQYVEQPKTYQSEAKTLLQNVSTEVCVPVTLVPVQMPDPQADLVQHTTQSHGILPPQHEQADYQRATDLSFLEKYTLTPQPANIVHPVRPEQMLDPRDQSYLGTLLGLDTAPTVQNISNNEHS", "length": 905, "header": "tr|E1C1B5-1|E1C1B5_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 41 OS=Gallus gallus OX=9031 GN=ZBTB41 PE=4 SV=2 CANONICAL=E1C1B5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y6J7-1", "url": "https://www.uniprot.org/uniprotkb/E1C1B5/entry#A0A8V0Y6J7-1", "sequence": { "sequence": "MKKRRRLAANVNEKVHLGREKVASDQILVVDCAQEIVSKPAEIAPADQLESAPELSPSSEQRKLLSSLQYNKNLLKYLNDDRQKRPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKNEIPLVLEAAKFLDIIDAVKLLNNESVSSIQSDVVTDTPTPVETLNELTGKLLNSHQCTFCGRSFCYKKSLENHLAKAHRSLSLERKHGLKMVEKAGFSTRRSTRNRKCPVKFDDSDSESDDASDSNLEKVNSDKEPSDRSEFEDSGSECNADEEGQEEEMSGEDSDTEEQSEKEHDTEEGSEVADSVGSIPEGLAPVIIQSSNKKLLQCPKCDKKFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSSDTDFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENVQEFLSIKKTKSEGWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECEECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCEVCKKVFKGKSSLEMHFRTHSDARPFNCQHCNATFKRKDKLKYHIDHVHGTKAAEEALTSSSEEKLVSLPVPYTSDDKVYQTEAKQYVEQPKTYQSEAKTLLQNVSTEVCVPVTLVPVQMPDPQADLVQHTTQSHGILPPQHEQADYQRATDLSFLEKYTLTPQPANIVHPVRPEQMLDPRDQSYLGTLLGLDTAPTVQNISNNEHS", "length": 877, "header": "tr|A0A8V0Y6J7-1|E1C1B5_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 41 OS=Gallus gallus OX=9031 GN=ZBTB41 PE=4 SV=1 CANONICAL=E1C1B5-1" }, "locus": { "chromosome": "8", "start_pos": 2606606, "end_pos": 2594396, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024706.1", "url": "https://www.ensembl.org/id/ENSGALT00010024706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014013.1", "url": "https://www.ensembl.org/id/ENSGALP00010014013.1" } ] } }, { "isoform_ac": "E1C1B5-1", "url": "https://www.uniprot.org/uniprotkb/E1C1B5/entry#E1C1B5-1", "sequence": { "sequence": "MKKRRRLAANVNEKVHLGREKVASDQILVVDCAQEIVSKPAEIAPADQLESAPELSPSSEQRKLLSSLQYNKNLLKYLNDDRQKRPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKNEIPLVLEAAKFLDIIDAVKLLNNESVSSIQSDVVTDTPTPVETLNELTGKLLNSHQCTFCGRSFCYKKSLENHLAKAHRSLSLERKHGLKMVEKAGFSTRRSTRNRKCPVKFDDSDSESDDASDSNLEKVNSDKEPSDRSEFEDSGSECNADEEGQEEEMSGEDSDTEEQSEKEHDTEEGSEVADSVGSIPEGLAPVIIQSSNKKLLQCPKCDKKFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSSDTDFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENVQEFLSIKKTKSEGWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECEECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCEVCKKVFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHMVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGTKAAEEALTSSSEEKLVSLPVPYTSDDKVYQTEAKQYVEQPKTYQSEAKTLLQNVSTEVCVPVTLVPVQMPDPQADLVQHTTQSHGILPPQHEQADYQRATDLSFLEKYTLTPQPANIVHPVRPEQMLDPRDQSYLGTLLGLDTAPTVQNISNNEHS", "length": 905, "header": "tr|E1C1B5-1|E1C1B5_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 41 OS=Gallus gallus OX=9031 GN=ZBTB41 PE=4 SV=2 CANONICAL=E1C1B5-1" }, "locus": { "chromosome": "8", "start_pos": 2606606, "end_pos": 2594396, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010024708.1", "url": "https://www.ensembl.org/id/ENSGALT00010024708.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014014.1", "url": "https://www.ensembl.org/id/ENSGALP00010014014.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BEL6-1", "protein_name": "Zinc finger and BTB domain-containing protein 41", "gene_name": "ZBTB41", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKRRKVTSHLEKIHLGYHKDSSDGNVAAECEQITCTHSTERPAPDTLRCYQELPPSPDQRTLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSADVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVATFQSELTEKSSPEETLSELTGRLSNNHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERGFSARRPKRNRKCPVKFDDTSDDEQESGDGSDNLNQDHFDKEKSDRNDSEDPGSEYNAEEDELEEEMSDEYSDIEEQSEKDQNDAEEEPEAGDSVGSIHEGLTPVVIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNETEFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCPHCNATFKRKDKLKYHIDHVHGIKSPDDPLSASEEKLVSLPVEYSSDDKIFQTETKQYMDPPKAYQSEAKTMFQNVSAEVCVPVTLVPVQRPDSQSDLVRHTTTLPPPAHEILSPQPPSADYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREQSYLGTLLGLDNAPAVQNISNSEHHS", "length": 909 }, "evidence": [ { "id": "E1C1B5", "url": "https://omabrowser.org/oma/group/E1C1B5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M953-1", "protein_name": "Zinc finger and BTB domain-containing protein 41", "gene_name": "Zbtb41", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKKRRKVTSNLDEKIHLGYHKDSSEENAAVECSQVTYPQATERPTPEALQCYQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNESVATFQAELTEKSSPEETLNELTGRLSSNHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKQHGLKMLERSFSARRSKRNRKCPVKFEDTSDDEQESGGGSDSLNQESFDKEKSDRNDSEDPGSEYNAEDDELEEEMSDEESDTEQSDKDNDAEEEPEAGDSAGSVQEGLAPVIIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNEVEFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGIKSPEDSLSTSEEKLVSLPTIEYSSDDKIFQAETKQYLDQPKVYQPEAKTLLQNVSAEVCVPVTLVPVQMPDTSSDLVPHTTTLPPSSHEMLPPQPQPTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREPSYLGTLLGLDSTTAVQNMSSSEHRSGVNIP", "length": 914 }, "evidence": [ { "id": "E1C1B5", "url": "https://omabrowser.org/oma/group/E1C1B5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MLT2-1", "protein_name": "Zinc finger and BTB domain-containing protein 41", "gene_name": "ZBTB41", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKRRKVTSHLDEKIHLGYHKDSPEGNVVEECDQVTYAHSTERPAPEALRCYQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVATFQSELTEKSSPEETLSELTGRLSSNHQCKFCSRHFCYKKSLENHLSKTHRSLLLGKKHGLKMLERSFSTRRSKRNRKCPVKFEDTSDDEQESGDGSDNLNQDSFDKEKSDRNDSEDPGSEYNAEEDELEEEMSDEYSDTEEQSEKDQNDAEEEPEAGDSVGSIHEGLTPVIIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNETEFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGIKSPDDPLSASEEKLVSLPVEYSSDDKIFQTETKQYMEQPKVYQSEAKTMLQNVSAEVCVPVTLVPVQMPDTQGDLVRHTTTLPPPAHEILSPQPPATDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREQSYLGTLLGLDNSTAVQNISNSEHHS", "length": 910 }, "evidence": [ { "id": "E1C1B5", "url": "https://omabrowser.org/oma/group/E1C1B5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F6PFI6-1", "protein_name": "Zinc finger and BTB domain-containing protein 41", "gene_name": "zbtb41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKKKLNPKETQETTTACNSKRDVGMTIKDFSLEKKCLRISQNDGCFLKFLNEDRHKLSSFCDTTVTVSGRIYHAHKVVLAFGSGYFHSRFSENPELHHVSIDNMEGSTFGHLLNFLYTSEFEVSECQIPALAEAACFLDMMEAVNILAKWAAPANADEESEVPEEIPNFQNIQTSSGTKCLFCSRTFNYKKSLENHLAKTHSTGCHNEEEQTVVSTSVVTIRRSARQRRVPAKFKSQDSENECVVSAKPNQKIANHNSVTYEEEEEDNESKEENENEQIQQESWKEGQEETFVALEVEAAEYEDCEKPKEACVSEAQKETEPAFSHALEEHNQKTEVSSHIFPEGLAPVVIHSTNKKSLKCPKCDKIFDRKGKYESHTRVHTGEKPFQCDICLQCYSTKSNLTVHKKKHDSGTPVQRKEHKCPFCNKLHASKKTLSRHVKRFHPDHLQEFLTQKKKSEVWKCDICHKSFSRRPHLEEHMILHSQDKPFKCAYCDDYFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNRKRHIECTHGGKRKWTCFLCGKSVRERTTLREHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHEDKRYECEECGKTFIRHDHLKKHKKIHTGEKAHQCEECGKCFRRADHLTVHYKSIHLGEKIWQRYKAVVHQCQVCKKEFRGKTNLMSHFRTHSGEKPHKCVICNQTFSIKKTLTKHMVIHSDVRPFNCPHCSATFKRKDKLKYHVDHVHSVRLLDQQQNQPASPANKLIDPSLSNKNSKPCQNASKTVLQSVAADVCVPVTLIPVQMTEEADLAVHGVPHGILPALSQPQQSYQSATDLVFLEKYTLTPQPTNIVHPVRVEQMLDPREQSYLGTLLGLDSATPVQNTSSAEHTQ", "length": 889 }, "evidence": [ { "id": "E1C1B5", "url": "https://omabrowser.org/oma/group/E1C1B5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5SVQ8-1", "protein_name": "Zinc finger and BTB domain-containing protein 41", "gene_name": "ZBTB41", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKRRKVTSNLEKIHLGYHKDSSEGNVAVECDQVTYTHSAGRPTPEALHCYQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVAPFHSELTEKSSPEETLNELTGRLSNNHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERSFSARRSKRNRKCPVKFDDTSDDEQESGDGSDNLNQENFDKEKSDRNDSEDPGSEYNAEEDELEEEMSDEYSDIEEQSEKDHNDAEEEPEAGDSVGNVHEGLTPVVIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNETEFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHEIKSPDDPLSTSEEKLVSLPVEYSSDDKIFQTETKQYMDQPKVYQSEAKTMLQNVSAEVCVPVTLVPVQMPDTPSDLVRHTTTLPPSSHEILSPQPQSTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREQSYLGTLLGLDSTTGVQNISTNEHHS", "length": 909 }, "evidence": [ { "id": "E1C1B5", "url": "https://omabrowser.org/oma/group/E1C1B5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q811F1-1", "protein_name": "Zinc finger and BTB domain-containing protein 41", "gene_name": "Zbtb41", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKRRKVTSNLDEKIHLGYHKDSSEENAAVECGQVTYTQAPERPTPEAAQRCQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVAAFQAELTEKSSPEETLNELTGRLSSSHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERSFSTRRSKRNRKCPVKFEDTSDDEQESGDGSDNLHQESSEKERSDRNDSEDPGSEYNAEDEELEEEVSDEDSDTEQSDKDNDAEEEPEAGDSAGSIHEGLAPVIIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNEVEFHRKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGIKSPDDSLSTSEEKLMSLPMEYSSDDKIFQAETKQYLDQPKVYQSEAKTMLQNVSAEVCVPVTLVPVQMPDTSSDLVPHTTTLPTSSHEMLPPQPQSTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREPSYLGTLLGLDSTAAVQNMCSSEHRS", "length": 908 }, "evidence": [ { "id": "E1C1B5", "url": "https://omabrowser.org/oma/group/E1C1B5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E1C1B5", "url": "https://www.uniprot.org/uniprotkb/E1C1B5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1B5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 905, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1B5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1B5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 528, "end_pos": 530 }, { "start_pos": 702, "end_pos": 704 }, { "start_pos": 730, "end_pos": 732 }, { "start_pos": 802, "end_pos": 804 }, { "start_pos": 898, "end_pos": 900 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C8B4-1", "uniprot_ac": "E1C8B4", "uniprot_id": "E1C8B4_CHICK", "mass": { "chemical_mass": 34608.0, "monoisotopic_mass": 34608.0 }, "refseq": { "ac": "XP_015146724", "name": "metallophosphoesterase domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146724" }, "gene_names": [ { "name": "MPPED1", "type": "recommended", "evidence": [ { "id": "E1C8B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8B4" } ] }, { "name": "MPPED1", "type": "synonym", "evidence": [ { "id": "XP_015146724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146724" } ] } ], "protein_names": [ { "name": "Metallophosphoesterase domain containing 1", "type": "synonym", "evidence": [ { "id": "E1C8B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8B4/entry#names_and_taxonomy" } ] }, { "name": "metallophosphoesterase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015146724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146724" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146724" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C8B4", "url": "https://www.uniprot.org/uniprotkb/E1C8B4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPPED1", "url": "https://www.uniprot.org/uniprotkb/E1C8B4", "locus": { "chromosome": "1", "start_pos": 68963686, "end_pos": 68900250, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011998", "url": "https://www.ensembl.org/id/ENSGALG00010011998" } ] } } ], "crossref": [ { "id": "E1C8B4", "url": "https://alphafold.ebi.ac.uk/entry/E1C8B4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014186", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014186", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07379", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07379", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418229", "url": "https://www.ncbi.nlm.nih.gov/gene/418229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051693", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051693", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418229", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418229", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IKTRICM", "url": "https://omabrowser.org/oma/group/IKTRICM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y777", "url": "https://www.orthodb.org/?gene=A0A8V0Y777", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YDE7", "url": "https://www.orthodb.org/?gene=A0A8V0YDE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C8B4", "url": "https://www.orthodb.org/?gene=E1C8B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12905:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12905:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00149", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146724", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y777", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y777", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y777-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y777-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YDE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8B4", "url": "https://www.uniprot.org/uniprotkb/E1C8B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8B4-1", "url": "https://www.uniprot.org/uniprotkb/E1C8B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFAQSHIMAARRHQHSRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCISDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPESYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPDGIDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRIQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPLNPPIVIDLPTPRNT", "length": 302, "header": "tr|E1C8B4-1|E1C8B4_CHICK Isoform 1 of Metallophosphoesterase domain containing 1 OS=Gallus gallus OX=9031 GN=MPPED1 PE=3 SV=1 CANONICAL=E1C8B4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y777-1", "url": "https://www.uniprot.org/uniprotkb/E1C8B4/entry#A0A8V0Y777-1", "sequence": { "sequence": "MGVRARPCQDPDPPACPPPSASGLRLSQPSLPAASPRSLKNIYVCPTAGESEAVRQGEGLSEEQGLPRGGGKRPAAPRALPPCRSAATRLPPGRRKGCAKVNPGCQPLSGALPSRPPPLSGRGAEGEAAALPPGSYFVSEFPRRLRAAGRREGGFVGPGQVRGRGPPRGSPGAAGAAARPGEGAVGAGELCWVVGEDVVTSKVLFREESVQQPWFYGWGFNLPRGQALLEKWNLIPDGIDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRIQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPLNPPIVIDLPTPRNT", "length": 326, "header": "tr|A0A8V0Y777-1|E1C8B4_CHICK Computationally mapped isoform of Metallophosphoesterase domain containing 1 OS=Gallus gallus OX=9031 GN=MPPED1 PE=3 SV=1 CANONICAL=E1C8B4-1" }, "locus": { "chromosome": "1", "start_pos": 68961083, "end_pos": 68900890, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028721.1", "url": "https://www.ensembl.org/id/ENSGALT00010028721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016523.1", "url": "https://www.ensembl.org/id/ENSGALP00010016523.1" } ] } }, { "isoform_ac": "A0A8V0YDE7-1", "url": "https://www.uniprot.org/uniprotkb/E1C8B4/entry#A0A8V0YDE7-1", "sequence": { "sequence": "MEHRGPHARPGSSGHGPGRGHSALRRRGAPRAGGEEGRAGGGGFLAPQRRWGRRGRGGEGEGRLGSRRTRRALAQNPAASEQPWRAGQPWFYGWGFNLPRGQALLEKWNLIPDGIDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRIQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPLNPPIVIDLPTPRNT", "length": 202, "header": "tr|A0A8V0YDE7-1|E1C8B4_CHICK Computationally mapped isoform of Metallophosphoesterase domain containing 1 OS=Gallus gallus OX=9031 GN=MPPED1 PE=3 SV=1 CANONICAL=E1C8B4-1" }, "locus": { "chromosome": "1", "start_pos": 68961083, "end_pos": 68900431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028726.1", "url": "https://www.ensembl.org/id/ENSGALT00010028726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016525.1", "url": "https://www.ensembl.org/id/ENSGALP00010016525.1" } ] } }, { "isoform_ac": "E1C8B4-1", "url": "https://www.uniprot.org/uniprotkb/E1C8B4/entry#E1C8B4-1", "sequence": { "sequence": "MAFAQSHIMAARRHQHSRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCISDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPESYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPDGIDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRIQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPLNPPIVIDLPTPRNT", "length": 302, "header": "tr|E1C8B4-1|E1C8B4_CHICK Isoform 1 of Metallophosphoesterase domain containing 1 OS=Gallus gallus OX=9031 GN=MPPED1 PE=3 SV=1 CANONICAL=E1C8B4-1" }, "locus": { "chromosome": "1", "start_pos": 68961083, "end_pos": 68914936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010028716.1", "url": "https://www.ensembl.org/id/ENSGALT00010028716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010016518.1", "url": "https://www.ensembl.org/id/ENSGALP00010016518.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418229", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418229", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QP02-1", "protein_name": "Metallophosphoesterase domain-containing protein 1", "gene_name": "Mpped1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWRPRWDPGILKAEALALLPCGLGMAFSQSHVMAARRHQHGRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQALLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPRNS", "length": 326 }, "evidence": [ { "id": "E1C8B4", "url": "https://omabrowser.org/oma/group/E1C8B4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0L833-1", "protein_name": "Metallophosphoesterase domain containing 1", "gene_name": "Mpped1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAPGPGGRRGPRRGRGSRGGRDSGGRARGAGARGRDRAPAGPGRAGGAARRRAGPGRRGAGRGRGRGRGEPPAPRRRSLAPTRSLGRAAQRPPPLRAALAGAGPPPPSARAAARGRRRGARGQSVRRSGGGPGRGGGSRGGGRCPGGRRRSMWRTRWDAGILKAEALALLPCGLGMAFSQSHVMASRRHQHGRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPRNS", "length": 478 }, "evidence": [ { "id": "E1C8B4", "url": "https://omabrowser.org/oma/group/E1C8B4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QUV1-1", "protein_name": "Metallophosphoesterase domain-containing protein 1 isoform X1", "gene_name": "mpped1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFTLSEIMAARRQQQQSQRGGRGVVEVDEYSANPTQAFTFYNINQGRFQPPHVHMVDPIAHDTPKPPGYTRFVCISDTHSRTDAIQMPYGDVLLHAGDFTELGLPSEVKKFNDWLGTLPYEIKIVIAGNHELTFDQEFMADLIKQDFYYFPSASKLKPENYENVQSLLTNCIYLQDSDVTVRGFRIYGSPWQPWYYGWGFNLPRGQALLDKWNQIPDSTDILLTHCPPLGFLDWVPRKMQRVGCMELLNTVQRRVQPKLHVFGHIHEGYGVMTDGTTTFVNASACTVNFQPMNPPIVFDLPNPRSS", "length": 307 }, "evidence": [ { "id": "E1C8B4", "url": "https://omabrowser.org/oma/group/E1C8B4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LHN0-1", "protein_name": "Metallophosphoesterase domain containing 1", "gene_name": "MPPED1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWRARWDPGVLKAEALALLPCGLGMAFSQSHVMAARRHQHSRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGFRVYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPRNS", "length": 326 }, "evidence": [ { "id": "E1C8B4", "url": "https://omabrowser.org/oma/group/E1C8B4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15442-1", "protein_name": "Metallophosphoesterase domain-containing protein 1", "gene_name": "MPPED1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWRSRWDASVLKAEALALLPCGLGMAFSQSHVMAARRHQHSRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPRNS", "length": 326 }, "evidence": [ { "id": "E1C8B4", "url": "https://omabrowser.org/oma/group/E1C8B4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZG2-1", "protein_name": "Metallophosphoesterase domain-containing protein 1", "gene_name": "Mpped1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRPRWDPGILKAEALALLPCGLGMAFSQSHVMASRRHQHGRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPRNS", "length": 326 }, "evidence": [ { "id": "E1C8B4", "url": "https://omabrowser.org/oma/group/E1C8B4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cyclic-nucleotide phosphodiesterase activity", "id": "GO:0004112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004112", "evidence": [ { "database": "UniProtKB", "id": "E1C8B4", "url": "https://www.uniprot.org/uniprotkb/E1C8B4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1C8B4", "url": "https://www.uniprot.org/uniprotkb/E1C8B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C8B4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8B4" }, { "id": "PF00149", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00149" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcineurin-like phosphoesterase", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 263, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NSV3-1", "uniprot_ac": "F1NSV3", "uniprot_id": "F1NSV3_CHICK", "mass": { "chemical_mass": 14961.0, "monoisotopic_mass": 14961.0 }, "refseq": { "ac": "XP_420795", "name": "cytokine-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420795" }, "gene_names": [ { "name": "CYTL1", "type": "recommended", "evidence": [ { "id": "F1NSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSV3" } ] }, { "name": "CYTL1", "type": "synonym", "evidence": [ { "id": "XP_420795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420795" } ] } ], "protein_names": [ { "name": "Cytokine like 1", "type": "synonym", "evidence": [ { "id": "F1NSV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NSV3/entry#names_and_taxonomy" } ] }, { "name": "cytokine-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_420795", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420795" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420795" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NSV3", "url": "https://www.uniprot.org/uniprotkb/F1NSV3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYTL1", "url": "https://www.uniprot.org/uniprotkb/F1NSV3", "locus": { "chromosome": "4", "start_pos": 78406254, "end_pos": 78419971, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011205", "url": "https://www.ensembl.org/id/ENSGALG00010011205" } ] } } ], "crossref": [ { "id": "F1NSV3", "url": "https://alphafold.ebi.ac.uk/entry/F1NSV3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015015", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015015", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422849", "url": "https://www.ncbi.nlm.nih.gov/gene/422849", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422849", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422849", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYSRMLT", "url": "https://omabrowser.org/oma/group/CYSRMLT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Y8I0", "url": "https://www.orthodb.org/?gene=A0A8V0Y8I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NSV3", "url": "https://www.orthodb.org/?gene=F1NSV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15974", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15974", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15974:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15974:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420795", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420795", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8I0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Y8I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSV3", "url": "https://www.uniprot.org/uniprotkb/F1NSV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NSV3-1", "url": "https://www.uniprot.org/uniprotkb/F1NSV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLSLFALLSAALLARAAPPTCYSRVLSLSKEITESFKELQTSKAKDPCVETLPRLYLDIHNYCVLTKLRDFVAYPRCERVLEVSELKEKARSLYTIMISYCRRDLAFLTDDCNALESPIQSSIESSEDIDS", "length": 132, "header": "tr|F1NSV3-1|F1NSV3_CHICK Isoform 1 of Cytokine like 1 OS=Gallus gallus OX=9031 GN=CYTL1 PE=1 SV=2 CANONICAL=F1NSV3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Y8I0-1", "url": "https://www.uniprot.org/uniprotkb/F1NSV3/entry#A0A8V0Y8I0-1", "sequence": { "sequence": "MKSMSGDQGCDLQLPRTKMLLSLFALLSAALLARAAPPTCYSRVLSLSKEITESFKELQTSKAKDPCVETLPRLYLDIHNYCVLTKLRDFVAYPRCERVLEVSELKEKARSLYTIMISYCRRDLAFLTDDCNALESPIQSSIESSEDIDS", "length": 150, "header": "tr|A0A8V0Y8I0-1|F1NSV3_CHICK Computationally mapped isoform of Cytokine like 1 OS=Gallus gallus OX=9031 GN=CYTL1 PE=1 SV=1 CANONICAL=F1NSV3-1" }, "locus": { "chromosome": "4", "start_pos": 78410996, "end_pos": 78406815, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026766.1", "url": "https://www.ensembl.org/id/ENSGALT00010026766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015263.1", "url": "https://www.ensembl.org/id/ENSGALP00010015263.1" } ] } }, { "isoform_ac": "F1NSV3-1", "url": "https://www.uniprot.org/uniprotkb/F1NSV3/entry#F1NSV3-1", "sequence": { "sequence": "MLLSLFALLSAALLARAAPPTCYSRVLSLSKEITESFKELQTSKAKDPCVETLPRLYLDIHNYCVLTKLRDFVAYPRCERVLEVSELKEKARSLYTIMISYCRRDLAFLTDDCNALESPIQSSIESSEDIDS", "length": 132, "header": "tr|F1NSV3-1|F1NSV3_CHICK Isoform 1 of Cytokine like 1 OS=Gallus gallus OX=9031 GN=CYTL1 PE=1 SV=2 CANONICAL=F1NSV3-1" }, "locus": { "chromosome": "4", "start_pos": 78408764, "end_pos": 78406815, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026771.1", "url": "https://www.ensembl.org/id/ENSGALT00010026771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015264.1", "url": "https://www.ensembl.org/id/ENSGALP00010015264.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422849", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422849", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7INK0-1", "protein_name": "Cytokine-like protein 1", "gene_name": "Cytl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPRALPLLLPLLMVVLWPLVVEPAPPTCYSRMLTLSHEIMADFQSLQASEPEDSCVRHLPRLYLDIHNYCVLAKLRDFVASPQCWKMAEVDTLKDRVRKLYTIMNSFCRRDLVFLSDDCNALEYPIPETTGPPDWQS", "length": 138 }, "evidence": [ { "id": "F1NSV3", "url": "https://omabrowser.org/oma/group/F1NSV3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1S5H0-1", "protein_name": "Cytokine like 1", "gene_name": "CYTL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTPRLLPLLLLLLARPPAAQPTPPTCYSRMLALSREITADFQRLQATEPSEPCVRYLPRLYLDIHNYCVLDKLRDFVASPQCWRVAQVDALKDKVRKLYTIMNSFCRRDLVFLSDDCNALEYPIPVTTVRPDPQRRDPAAQTRDRTRGH", "length": 149 }, "evidence": [ { "id": "F1NSV3", "url": "https://omabrowser.org/oma/group/F1NSV3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9NRR1-1", "protein_name": "Cytokine-like protein 1", "gene_name": "CYTL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTPGPLPVLLLLLAGAPAARPTPPTCYSRMRALSQEITRDFNLLQVSEPSEPCVRYLPRLYLDIHNYCVLDKLRDFVASPPCWKVAQVDSLKDKARKLYTIMNSFCRRDLVFLLDDCNALEYPIPVTTVLPDRQR", "length": 136 }, "evidence": [ { "id": "F1NSV3", "url": "https://omabrowser.org/oma/group/F1NSV3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "F1NSV3", "url": "https://www.uniprot.org/uniprotkb/F1NSV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1K6-1", "uniprot_ac": "E1C1K6", "uniprot_id": "E1C1K6_CHICK", "mass": { "chemical_mass": 41041.0, "monoisotopic_mass": 41041.0 }, "refseq": { "ac": "XP_424808", "name": "RNA 3'-terminal phosphate cyclase-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424808" }, "gene_names": [ { "name": "RCL1", "type": "recommended", "evidence": [ { "id": "E1C1K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ] }, { "name": "RCL1", "type": "synonym", "evidence": [ { "id": "XP_424808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424808" } ] } ], "protein_names": [ { "name": "RNA 3'-terminal phosphate cyclase-like protein", "type": "recommended", "evidence": [ { "id": "E1C1K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1K6/entry#names_and_taxonomy" } ] }, { "name": "RNA 3'-terminal phosphate cyclase-like protein", "type": "synonym", "evidence": [ { "id": "XP_424808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424808" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424808" } ] }, { "annotation": "As part of the small subunit (SSU) processome, it plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA. Activates BMS1 by promoting GDP/GTP exchange. Does not have cyclase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YCA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA4#function" }, { "database": "UniProtKB", "id": "ARBA00056741", "url": "https://www.uniprot.org/uniprotkb/ARBA00056741#function" }, { "database": "UniProtKB", "id": "A0A8V0YGZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ2#function" }, { "database": "UniProtKB", "id": "A0A8V0YGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ7#function" }, { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6#function" }, { "database": "UniProtKB", "id": "A0A8V0YA32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA32#function" }, { "database": "UniProtKB", "id": "A0A8V0YA36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA36#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RCL1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6", "locus": { "chromosome": "Z", "start_pos": 27937669, "end_pos": 27896635, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011222", "url": "https://www.ensembl.org/id/ENSGALG00010011222" } ] } } ], "crossref": [ { "id": "E1C1K6", "url": "https://alphafold.ebi.ac.uk/entry/E1C1K6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015024", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015024", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00875", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00875", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427222", "url": 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"id": "IPR036553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427222", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427222", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YTDQNKG", "url": "https://omabrowser.org/oma/group/YTDQNKG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA32", "url": "https://www.orthodb.org/?gene=A0A8V0YA32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YA36", "url": "https://www.orthodb.org/?gene=A0A8V0YA36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YCA4", "url": "https://www.orthodb.org/?gene=A0A8V0YCA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGZ2", "url": "https://www.orthodb.org/?gene=A0A8V0YGZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YGZ7", "url": "https://www.orthodb.org/?gene=A0A8V0YGZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1K6", "url": "https://www.orthodb.org/?gene=E1C1K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11096:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11096:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_424808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YA32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YA36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YA36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YCA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YGZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1K6-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGGAQCLSFAGCNFLRQRLVLSTLSGRPLKIRKIRAKEEDPGLRDFEACFIRLIDKVTNGSRIEINQTGTTLYYQPGLLYGGSLEHDCSPSRSIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKKFGIDGESLEIKINRRGMPPKGGGEILFACPVRKVLQPIQFTDPGKIKRIRGTAYSVRVSPQMANRMVESARSVLNKFLPDVYIYTDHMKGISSGKSPGFGICLIAETINGTILSAELASNPQGQGAAVLPEELGQNCAKLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLRSFFQIMFKIEMKSPEEEHKGGEKVLMTCVGIGFSNLSKTIR", "length": 374, "header": "tr|E1C1K6-1|E1C1K6_CHICK Isoform 1 of RNA 3'-terminal phosphate cyclase-like protein OS=Gallus gallus OX=9031 GN=RCL1 PE=1 SV=3 CANONICAL=E1C1K6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YA32-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6/entry#A0A8V0YA32-1", "sequence": { "sequence": "MAGGGAQCLSFAGCNFLRQRLVLSTLSGRPLKIRKIRAKEEDPGLRDFEACFIRLIDKVTNGSRIEINQTGTTLYYQPGLLYGGSLEHDCSPSRSIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKKFGIDGESLEIKINRRGMPPKGGGEILFACPVRKVLQPIQFTDPGKIKRIRGTAYSVRVSPQMANRMVESARSVLNKFLPDVYIYTDHMKGISSGKSPGFGICLIAETINGTILSAELASNPQGQGAAVLPEELGQNCAKLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTLGVHGRDEGQQQTFWSIMCHKKSCNSVWSTLVPSLKRLVKDRKTWPSSSSSNQRVFELNCGTVIVILSFLCQSYDISVFKTFTLYTPKLFIRHI", "length": 419, "header": "tr|A0A8V0YA32-1|E1C1K6_CHICK Computationally mapped isoform of RNA 3'-terminal phosphate cyclase-like protein OS=Gallus gallus OX=9031 GN=RCL1 PE=1 SV=1 CANONICAL=E1C1K6-1" }, "locus": { "chromosome": "Z", "start_pos": 27926791, "end_pos": 27896794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026814.1", "url": "https://www.ensembl.org/id/ENSGALT00010026814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015281.1", "url": "https://www.ensembl.org/id/ENSGALP00010015281.1" } ] } }, { "isoform_ac": "A0A8V0YA36-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6/entry#A0A8V0YA36-1", "sequence": { "sequence": "MAGGGAQCLSFAGCNFLRQRLVLSTLSGRPLKIRKIRAKEEDPGLRDFEACFIRLIDKVTNGSRIEINQTGTTLYYQPGLLYGGSLEHDCSPSRSIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKKFGIDGESLEIKINRRGMPPKGGGEILFACPVRKVLQPIQFTDPGKIKRIRGTAYSVRVSPQMANRMVESARSVLNKFLPDVYIYTDHMKGISSGKSPGFGICLIAETINGTILSAELASNPQGQGAAVLPEELGQNCAKLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLRSFFQIMFKIEMKSPEEEHKAPQV", "length": 356, "header": "tr|A0A8V0YA36-1|E1C1K6_CHICK Computationally mapped isoform of RNA 3'-terminal phosphate cyclase-like protein OS=Gallus gallus OX=9031 GN=RCL1 PE=1 SV=1 CANONICAL=E1C1K6-1" }, "locus": { "chromosome": "Z", "start_pos": 27936952, "end_pos": 27896794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026823.1", "url": "https://www.ensembl.org/id/ENSGALT00010026823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015286.1", "url": "https://www.ensembl.org/id/ENSGALP00010015286.1" } ] } }, { "isoform_ac": "A0A8V0YCA4-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6/entry#A0A8V0YCA4-1", "sequence": { "sequence": "MAGGGAQCLSFAGCNFLRQRLVLSTLSGRPLKIRKIRAKEEDPGLRDFEACFIRLIDKVTNGSRIEINQTGTTLYYQPGLLYGGSLEHDCSPSRSIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKKFGIDGESLEIKINRRGMPPKGGGEILFACPVRKVLQPIQFTDPGKIKRIRGTAYSVRVSPQMANRMVESARSVLNKFLPDVYIYTDHMKGISSGKSPGFGICLIAETINGTILSAELASNPQGQGAAVLPEELGQNCAKLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLRSFFQIMFKIEMKSPEEEHKGAGSSYKDMNSYPIKSFW", "length": 370, "header": "tr|A0A8V0YCA4-1|E1C1K6_CHICK Computationally mapped isoform of RNA 3'-terminal phosphate cyclase-like protein OS=Gallus gallus OX=9031 GN=RCL1 PE=1 SV=1 CANONICAL=E1C1K6-1" }, "locus": { "chromosome": "Z", "start_pos": 27930813, "end_pos": 27896794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026817.1", "url": "https://www.ensembl.org/id/ENSGALT00010026817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015282.1", "url": "https://www.ensembl.org/id/ENSGALP00010015282.1" } ] } }, { "isoform_ac": "A0A8V0YGZ2-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6/entry#A0A8V0YGZ2-1", "sequence": { "sequence": "MAGGGAQCLSFAGCNFLRQRLVLSTLSGRPLKIRKIRAKEEDPGLRDFEACFIRLIDKVTNGSRIEINQTGTTLYYQPGLLYGGSLEHDCSPSRSIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKKFGIDGESLEIKINRRGMPPKGGGEILFACPVRKVLQPIQFTDPGKIKRIRGTAYSVRVSPQMANRMVESARSVLNKFLPDVYIYTDHMKGISSGKSPGFGICLIAETINGTILSAELASNPQGQGAAVLPEELGQNCAKLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTCVSIALYFLSRLISDG", "length": 341, "header": "tr|A0A8V0YGZ2-1|E1C1K6_CHICK Computationally mapped isoform of RNA 3'-terminal phosphate cyclase-like protein OS=Gallus gallus OX=9031 GN=RCL1 PE=1 SV=1 CANONICAL=E1C1K6-1" }, "locus": { "chromosome": "Z", "start_pos": 27926488, "end_pos": 27896794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026809.1", "url": "https://www.ensembl.org/id/ENSGALT00010026809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015280.1", "url": "https://www.ensembl.org/id/ENSGALP00010015280.1" } ] } }, { "isoform_ac": "A0A8V0YGZ7-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6/entry#A0A8V0YGZ7-1", "sequence": { "sequence": "MAGGGAQCLSFAGCNFLRQRLVLSTLSGRPLKIRKIRAKEEDPGLRDFEACFIRLIDKVTNGSRIEINQTGTTLYYQPGLLYGGSLEHDCSPSRSIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKKFGIDGESLEIKINRRGMPPKGGGEILFACPVRKVLQPIQFTDPGKIKRIRGTAYSVRVSPQMANRMVESARSVLNKFLPDVYIYTDHMKGISSGKSPGFGICLIAETINGTILSAELASNPQGQGAAVLPEELGQNCAKLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLRSFFQIMFKIEMKSPEEEHKGE", "length": 354, "header": "tr|A0A8V0YGZ7-1|E1C1K6_CHICK Computationally mapped isoform of RNA 3'-terminal phosphate cyclase-like protein OS=Gallus gallus OX=9031 GN=RCL1 PE=1 SV=1 CANONICAL=E1C1K6-1" }, "locus": { "chromosome": "Z", "start_pos": 27935759, "end_pos": 27896794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026822.1", "url": "https://www.ensembl.org/id/ENSGALT00010026822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015285.1", "url": "https://www.ensembl.org/id/ENSGALP00010015285.1" } ] } }, { "isoform_ac": "E1C1K6-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K6/entry#E1C1K6-1", "sequence": { "sequence": "MAGGGAQCLSFAGCNFLRQRLVLSTLSGRPLKIRKIRAKEEDPGLRDFEACFIRLIDKVTNGSRIEINQTGTTLYYQPGLLYGGSLEHDCSPSRSIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKKFGIDGESLEIKINRRGMPPKGGGEILFACPVRKVLQPIQFTDPGKIKRIRGTAYSVRVSPQMANRMVESARSVLNKFLPDVYIYTDHMKGISSGKSPGFGICLIAETINGTILSAELASNPQGQGAAVLPEELGQNCAKLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLRSFFQIMFKIEMKSPEEEHKGGEKVLMTCVGIGFSNLSKTIR", "length": 374, "header": "tr|E1C1K6-1|E1C1K6_CHICK Isoform 1 of RNA 3'-terminal phosphate cyclase-like protein OS=Gallus gallus OX=9031 GN=RCL1 PE=1 SV=3 CANONICAL=E1C1K6-1" }, "locus": { "chromosome": "Z", "start_pos": 27930522, "end_pos": 27896794, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026820.1", "url": "https://www.ensembl.org/id/ENSGALT00010026820.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015283.1", "url": "https://www.ensembl.org/id/ENSGALP00010015283.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427222", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427222", "resource": "KEGG Pathway" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V7Z1-1", "protein_name": "RNA 3'-terminal phosphate cyclase-like protein", "gene_name": "Rcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRRIRARDDNPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLEALLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKILRRGMPPGGGGEVLFSCPVRKVLKPVQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARGILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTNGTFLSAELASNPQGQGAAVLPEDLGRNCAKLLLEEIYRGGCVDSTSQSLVLLLMTLGQQDVSKVLLGPLSPYTIEFLRHLKSFFQVMFKVETKPCGEELKGGDKVLMTCVGIGFSNLSKTLK", "length": 373 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56175-1", "protein_name": "Probable RNA 3'-terminal phosphate cyclase-like protein", "gene_name": "Rtc1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPIAQEGNCLIYRGSNFLKQRLILACLSGKPVKISQIRSEDETAPGLREYEISLIRLLDKITNGTKIELNPAGTSVMFSPGLLHGGQLNHDCCVQRGIGYYLDALIALGPFCKSPLQCTLRGVTNSKDSPSVDHIKGAALSLLKRFLLVDEGLELKVVRRGVAPLGGGEIIFRCPVRKSLRAIQFQSQGMVKRIRGTVYACKVSPAMANRTVEAAKGCMLKFLPDVYIYTDQNKGKMSGNSPGFGICLIAETTDGVCFAADCCSNTREESEDTPSIPENLGKEVALRLLDEIYRGGCVDSSYQWLAALYIALGQKHVSKFLTGALSNYTVHFLQHLRDFFSITFKLENPEAEDEDEAENVRGAQKVLMACVGIGYTNINKRVI", "length": 384 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q08096-1", "protein_name": "rRNA processing protein RCL1", "gene_name": "RCL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSSAPKYTTFQGSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLIESVTNGSVIEISYTGTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYLAPFSKKKFSILFKGITASHNDAGIEAIKWGLMPVMEKFGVRECALHTLKRGSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSITGVAYSTRVSPSLVNRMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQKGWSYFAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKEDIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIKGIGFTNTSKKIA", "length": 367 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KHX8-1", "protein_name": "RNA 3'-terminal phosphate cyclase-like protein", "gene_name": "RCL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASQAHSLSYSGCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKVTNGSRIEINQTGTTLYYQPGLLYGGSMEHDCSVLRGIGYYLESLLCLAPFMKHPLRIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKVVRRGMPPGGGGEVFFSCPVRKVLKPIQLIDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGINSGKSPGFGLSLVAETTNGTFLSAELASNPQGQGAAMLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLKSFFQIMFKIETKPCGEELKGGDKVLMTCVGIGFSNLSKTLK", "length": 373 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54S38-1", "protein_name": "Probable RNA 3'-terminal phosphate cyclase-like protein", "gene_name": "rcl1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKFQGSTHFRQRIICSTLSGKAIRITNIRDEDEKPGLRDYEASFLRLVDKITNGSKIEINSTGTQITYIPGIIIGGKGITHECGTVRGIGYFVEALICLGPFAKAPLDITLNGITNNDIDLTIDTIRTTTLPIIRKFGIEEGLIIKIIKRGAPPNGGGSVNFKCPIVPHLKAIQLIDEGKIRRIRGIAYATRISPQFSNRVLDKAKGLLLEYTPDVYISSDHYKGNESGLSPGYGLTLVAETTTGCCLSAECMSNTGIATTEQQLQKQKSTSETPEDLGERTAFALLEEIFNGGCIDSHNQSLALLFMVLCPEDISKVRLGKITPYTIEFIRQLRDFFGVTFKIEPDQNSKTVLFTCLGIGYKNMARSTF", "length": 371 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9C578-1", "protein_name": "Probable RNA 3'-terminal phosphate cyclase-like protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVMMKKMKGSQSFRQRLLLSTLSSTPISIDEIRADETIPGLRPHEVNLLRLLEIVTDDAVVDINETGTRLKYKPGTIVGGKNLVHSCSLSRSIGYYLEPLLLLGLFGKKPLSIRLKGITNDPRDASVDTFRSTTLNIIKRFGVPAEDLELKIEARGVAPNGGGEVLLTVPNIKTLSAVHWVEEGMVKKIRGTTFSTRVTSDFEHSMRFAARGIFNNLLPDVHIFQDHRAGAQAGKSPGYGISLAAETTTGCFISADTTVSCERPDETGELDVEKKERSPAEDTGVEVASWLLQEIEKGGVVDSTHQGLLFLLCALSEQDVSKVRVGTLSPYAVETLRNIKEFLGVKFAIKPDPLTGTVILKCTGSGLINLSRKLS", "length": 375 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JJT0-1", "protein_name": "RNA 3'-terminal phosphate cyclase-like protein", "gene_name": "Rcl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRRIRARDDNPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLEALLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKILRRGMPPGGGGEVLFSCPVRKVLKPVQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVSSGKSPGFGLSLVAETTNGTFLSAELASNPQGQGAAVLPEDLGRNCAKLLLEEIYRGGCVDSTNQSLVLLLMTLGQQDVSKVLLGPLSPYTIEFLRHLKSFFQVMFKVETKPCGEELKGGDKVLMTCVGIGFSNLSKTLK", "length": 373 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2P8-1", "protein_name": "RNA 3'-terminal phosphate cyclase-like protein", "gene_name": "RCL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKITNGSRIEINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCPVRKVLKPIQLTDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTSGTFLSAELASNPQGQGAAVLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSPYTIEFLRHLKSFFQIMFKIETKPCGEELKGGDKVLMTCVGIGFSNLSKTLK", "length": 373 }, "evidence": [ { "id": "E1C1K6", "url": "https://omabrowser.org/oma/group/E1C1K6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000479", "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "pmid": "" }, { "name": "ribosomal small subunit biogenesis", "id": "GO:0042274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042274", "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "pmid": "" }, { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "E1C1K6", "url": "https://www.uniprot.org/uniprotkb/E1C1K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 252, "end_pos": 254 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NBA4-1", "uniprot_ac": "F1NBA4", "uniprot_id": "F1NBA4_CHICK", "mass": { "chemical_mass": 11369.0, "monoisotopic_mass": 11369.0 }, "refseq": {}, "gene_names": [ { "name": "GLRX", "type": "recommended", "evidence": [ { "id": "F1NBA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" } ] } ], "protein_names": [ { 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Reduces low molecular weight disulfides and proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YB63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB63#function" }, { "database": "UniProtKB", "id": "ARBA00002549", "url": "https://www.uniprot.org/uniprotkb/ARBA00002549#function" }, { "database": "UniProtKB", "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLRX", "url": "https://www.uniprot.org/uniprotkb/F1NBA4", "locus": { "chromosome": "Z", "start_pos": 58167978, "end_pos": 58159316, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012918", "url": "https://www.ensembl.org/id/ENSGALG00010012918" } ] } } ], "crossref": [ { "id": "F1NBA4", "url": "https://alphafold.ebi.ac.uk/entry/F1NBA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027483", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027483", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03419", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03419", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396069", "url": "https://www.ncbi.nlm.nih.gov/gene/396069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396069", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KPGHLEC", "url": "https://omabrowser.org/oma/group/KPGHLEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YB63", "url": "https://www.orthodb.org/?gene=A0A8V0YB63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NBA4", "url": "https://www.orthodb.org/?gene=F1NBA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46185:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46185:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-499943", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-499943", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_990491", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990491", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YB63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YB63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YB63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NBA4-1", "url": "https://www.uniprot.org/uniprotkb/F1NBA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDSFVQSKLRDNKVTLFVKGSCPYCKNAIALLKEFNFLPGCLEVVDITGMDDIQDYFQKTTGQRTVPRVFIGTKCIGGFSDLQKMEQQLPMMLRQIGALV", "length": 101, "header": "tr|F1NBA4-1|F1NBA4_CHICK Isoform 1 of Glutaredoxin-1 OS=Gallus gallus OX=9031 GN=GLRX PE=3 SV=2 CANONICAL=F1NBA4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YB63-1", "url": "https://www.uniprot.org/uniprotkb/F1NBA4/entry#A0A8V0YB63-1", "sequence": { "sequence": "MVDSFVQSKLRDNKVTLFVKGSCPYCKNAIALLKEFNFLPGCLEVVDITGMDDIQDYFQKTTGQRTEPGAKWSCSQKHHHQTPDPPGVPRVFIGTKCIGGFSDLQKMEQQLPMMLRQIGALV", "length": 122, "header": "tr|A0A8V0YB63-1|F1NBA4_CHICK Computationally mapped isoform of Glutaredoxin-1 OS=Gallus gallus OX=9031 GN=GLRX PE=3 SV=1 CANONICAL=F1NBA4-1" }, "locus": { "chromosome": "Z", "start_pos": 58162426, "end_pos": 58159437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030996.1", "url": "https://www.ensembl.org/id/ENSGALT00010030996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018012.1", "url": "https://www.ensembl.org/id/ENSGALP00010018012.1" } ] } }, { "isoform_ac": "F1NBA4-1", "url": "https://www.uniprot.org/uniprotkb/F1NBA4/entry#F1NBA4-1", "sequence": { "sequence": "MVDSFVQSKLRDNKVTLFVKGSCPYCKNAIALLKEFNFLPGCLEVVDITGMDDIQDYFQKTTGQRTVPRVFIGTKCIGGFSDLQKMEQQLPMMLRQIGALV", "length": 101, "header": "tr|F1NBA4-1|F1NBA4_CHICK Isoform 1 of Glutaredoxin-1 OS=Gallus gallus OX=9031 GN=GLRX PE=3 SV=2 CANONICAL=F1NBA4-1" }, "locus": { "chromosome": "Z", "start_pos": 58162426, "end_pos": 58159437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010030999.1", "url": "https://www.ensembl.org/id/ENSGALT00010030999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018015.1", "url": "https://www.ensembl.org/id/ENSGALP00010018015.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396069", "resource": "KEGG Pathway" }, { "id": "R-GGA-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TZS4-1", "protein_name": "Glutaredoxin-1", "gene_name": "LOC101902340", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQAFVNSKIQPGKVVVFIKPTCPYCRKTQELLSQLPFKQGLLEFVDITAAGNTSEIQDYLQQLTGARTVPRVFIGQECIGGCTDLVNTHERGELLTRLKQIGALQ", "length": 106 }, "evidence": [ { "id": "F1NBA4", "url": "https://omabrowser.org/oma/group/F1NBA4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H756-1", "protein_name": "Glutaredoxin-1", "gene_name": "Glrx", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQEFVNCKIQPGKVVVFIKPTCPYCQRTQEILRQLPFKPGLLEFVDITATNNTNEIQDYLQQLTGARTVPRVFIGKDCIGGCNDLITMQQNGKLMTRLKQIGALQ", "length": 106 }, "evidence": [ { "id": "F1NBA4", "url": "https://omabrowser.org/oma/group/F1NBA4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P12309-1", "protein_name": "Glutaredoxin-1", "gene_name": "GLRX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQAFVNSKIQPGKVVVFIKPTCPFCRKTQELLSQLPFKEGLLEFVDITATSDTNEIQDYLQQLTGARTVPRVFIGKECIGGCTDLESMHKRGELLTRLQQIGALK", "length": 106 }, "evidence": [ { "id": "F1NBA4", "url": "https://omabrowser.org/oma/group/F1NBA4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P35754-1", "protein_name": "Glutaredoxin-1", "gene_name": "GLRX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ", "length": 106 }, "evidence": [ { "id": "F1NBA4", "url": "https://omabrowser.org/oma/group/F1NBA4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ESH6-1", "protein_name": "Glutaredoxin-1", "gene_name": "Glrx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEFVNCKIQSGKVVVFIKPTCPYCRKTQEILSQLPFKRGLLEFVDITATNNTNAIQDYLQQLTGARTVPRVFIGKDCIGGCSDLLSMQQNGELTARLKQIGALQL", "length": 107 }, "evidence": [ { "id": "F1NBA4", "url": "https://omabrowser.org/oma/group/F1NBA4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QUH0-1", "protein_name": "Glutaredoxin-1", "gene_name": "Glrx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQEFVNCKIQSGKVVVFIKPTCPYCRKTQEILSQLPFKQGLLEFVDITATNNTSAIQDYLQQLTGARTVPRVFIGKDCIGGCSDLISMQQTGELMTRLKQIGALQL", "length": 107 }, "evidence": [ { "id": "F1NBA4", "url": "https://omabrowser.org/oma/group/F1NBA4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutathione disulfide oxidoreductase activity", "id": "GO:0015038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015038", "evidence": [ { "database": "UniProtKB", "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of membrane potential", "id": "GO:0045838", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045838", "evidence": [ { "database": "UniProtKB", "id": "F1NBA4", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NBA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBA4" }, { "id": "PF00462", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glutaredoxin", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 77, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NJK4-1", "uniprot_ac": "F1NJK4", "uniprot_id": "F1NJK4_CHICK", "mass": { "chemical_mass": 34171.0, "monoisotopic_mass": 34171.0 }, "refseq": { "ac": "NP_001264302", "name": "serine hydrolase-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264302" }, "gene_names": [ { "name": "SERHL", "type": "recommended", "evidence": [ { "id": "F1NJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK4" } ] }, { "name": "SERHL2", "type": "synonym", "evidence": [ { "id": "NP_001264302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264302" } ] }, { "name": "SERHL", "type": "synonym", "evidence": [ { "id": "NP_001264302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264302" } ] } ], "protein_names": [ { "name": "Serine hydrolase-like (pseudo", "type": "synonym", "evidence": [ { "id": "F1NJK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJK4/entry#names_and_taxonomy" } ] }, { "name": "serine hydrolase like 2", "type": "synonym", "evidence": [ { "id": "NP_001264302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264302" } ] }, { "name": "serine hydrolase-like protein 2", "type": "synonym", "evidence": [ { "id": "NP_001264302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264302" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01003418.1, HAEK01004367.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000012.1. On Apr 5, 2013 this sequence version replaced XP_416214.2. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264302" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NJK4", "url": "https://www.uniprot.org/uniprotkb/F1NJK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SERHL", "url": "https://www.uniprot.org/uniprotkb/F1NJK4", "locus": { "chromosome": "1", "start_pos": 49243896, "end_pos": 49252104, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010978", "url": "https://www.ensembl.org/id/ENSGALG00010010978" } ] } } ], "crossref": [ { "id": "F1NJK4", "url": "https://alphafold.ebi.ac.uk/entry/F1NJK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000011867", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011867", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417976", "url": "https://www.ncbi.nlm.nih.gov/gene/417976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417976", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGWMDVS", "url": "https://omabrowser.org/oma/group/HGWMDVS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBA6", "url": "https://www.orthodb.org/?gene=A0A8V0YBA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YBB4", "url": "https://www.orthodb.org/?gene=A0A8V0YBB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJK4", "url": "https://www.orthodb.org/?gene=F1NJK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264302", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YBA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBB4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YBB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YBB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJK4", "url": "https://www.uniprot.org/uniprotkb/F1NJK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJK4-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSEVKFPVPWGHVAAKAWGPPEGHPVLCLHGWLDNANTFDRLIPLLPRDCRYVAMDFSGHGLSSHRPAGSPYHFLDYVSDVRRVAAALRWRRFTLMGHSMGGSVAGMFAFIYPEMVDKLILLENLGFLLAPEDTEAWLKSKRLAIDRLLSLEAKQQAPKARSPEAALQRLLEANRHLTAEGGAILLQRGATETPTGLVYNRDMRVRTQSREYLTVEQCVKLLQKIKDRVLIILAQDGLLVPHKLESRNQFVKSLREAFEHTLKEDIQLVEVPGSHFVHLNEPEVVSGIISNFLTAQNTRARL", "length": 303, "header": "tr|F1NJK4-1|F1NJK4_CHICK Isoform 1 of Serine hydrolase-like (pseudo OS=Gallus gallus OX=9031 GN=SERHL PE=1 SV=2 CANONICAL=F1NJK4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YBA6-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK4/entry#A0A8V0YBA6-1", "sequence": { "sequence": "MFSEVKFPVPWGHVAAKAWGPPEGHPVLCLHGWLDNANTFDRLIPLLPRDCRYVAMDFSGHGLSSHRPAGSPYHFLDYVSDVRRVAAALRWRRFTLMGHSMGGSVAGMDTEAWLKSKRLAIDRLLSLEAKQQAPKARSPEAALQRLLEANRHLTAEGGAILLQRGATETPTGLVYNRDMRVRTQSREYLTVEQCVKLLQKIKDRVLIILAQDGLLVPHKLESRNQFVKSLREAFEHTLKEDIQLVEVPGSHFVHLNEPEVVSGIISNFLTAQNTRARL", "length": 278, "header": "tr|A0A8V0YBA6-1|F1NJK4_CHICK Computationally mapped isoform of Serine hydrolase-like (pseudo OS=Gallus gallus OX=9031 GN=SERHL PE=1 SV=1 CANONICAL=F1NJK4-1" }, "locus": { "chromosome": "1", "start_pos": 49251077, "end_pos": 49244512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026297.1", "url": "https://www.ensembl.org/id/ENSGALT00010026297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014921.1", "url": "https://www.ensembl.org/id/ENSGALP00010014921.1" } ] } }, { "isoform_ac": "A0A8V0YBB4-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK4/entry#A0A8V0YBB4-1", "sequence": { "sequence": "MFSEVKFPVPWGHVAAKAWGPPEGHPVLCLHGWLDNANTFDRLIPLLPRDCRYVAMDFSGHGLSSHRPAGSPYHFLDYVSDVRRVAAALRWRRFTLMGHSMGGSVAGMFAFIYPEMVDKLILLENLGFLLAPEDTEAWLKSKRLAIDRLLSLEAKQQAPKARSPEAALQRLLEANRHLTAEGGAILLQRGATETPTGLVYNRDMRVRTSREYLTVEQCVKLLQKIKDRVLIILAQDGLLVPHKLESRNQFVKSLREAFEHTLKEDIQLVEVPGSHFVHLNEPEVVSGIISNFLTAQNTRARL", "length": 302, "header": "tr|A0A8V0YBB4-1|F1NJK4_CHICK Computationally mapped isoform of Serine hydrolase-like (pseudo OS=Gallus gallus OX=9031 GN=SERHL PE=1 SV=1 CANONICAL=F1NJK4-1" }, "locus": { "chromosome": "1", "start_pos": 49251077, "end_pos": 49244512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026307.1", "url": "https://www.ensembl.org/id/ENSGALT00010026307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014931.1", "url": "https://www.ensembl.org/id/ENSGALP00010014931.1" } ] } }, { "isoform_ac": "F1NJK4-1", "url": "https://www.uniprot.org/uniprotkb/F1NJK4/entry#F1NJK4-1", "sequence": { "sequence": "MFSEVKFPVPWGHVAAKAWGPPEGHPVLCLHGWLDNANTFDRLIPLLPRDCRYVAMDFSGHGLSSHRPAGSPYHFLDYVSDVRRVAAALRWRRFTLMGHSMGGSVAGMFAFIYPEMVDKLILLENLGFLLAPEDTEAWLKSKRLAIDRLLSLEAKQQAPKARSPEAALQRLLEANRHLTAEGGAILLQRGATETPTGLVYNRDMRVRTQSREYLTVEQCVKLLQKIKDRVLIILAQDGLLVPHKLESRNQFVKSLREAFEHTLKEDIQLVEVPGSHFVHLNEPEVVSGIISNFLTAQNTRARL", "length": 303, "header": "tr|F1NJK4-1|F1NJK4_CHICK Isoform 1 of Serine hydrolase-like (pseudo OS=Gallus gallus OX=9031 GN=SERHL PE=1 SV=2 CANONICAL=F1NJK4-1" }, "locus": { "chromosome": "1", "start_pos": 49251077, "end_pos": 49244512, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026302.1", "url": "https://www.ensembl.org/id/ENSGALT00010026302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014926.1", "url": "https://www.ensembl.org/id/ENSGALP00010014926.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417976", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZYD0-1", "protein_name": "Serine hydrolase like 2", "gene_name": "SERHL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSELKLAVPWGHIAAKIWGPQQGSPVLCLHGWLDNANSFDRLIPLLPKDFHYVAMDFGGHGLSSHYSPGFPYYHQNFVTEVRRVVAGKSPVSFFLFYSFFPSCVTSQFSCIFPEMVDKLILLDSSPFVLDTNEVESMLSYKRRAIEHTLQLEASNKPSKVVSPQEMLQGWVLLKNNSHVGEECGALLLQRGTTPVAAGLVMNRDRRISWPEQSFEFISRELFVHAIKQLQARVLLIKAAQGFYNVRRENDADKEPMQFVTSTLRSILQERFQYVEVPGNHYVHLNQPQHVAGVISSFLQSKAIPAQL", "length": 307 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1M6I1-1", "protein_name": "Serine hydrolase like 2", "gene_name": "SERHL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLISELKLAVPWGHIAAKAWGSHQAAPVLCLHGWLDNANSFDRLIPLLPKDFNYVAMDFGGHGLSSHYSPGFPYHYQNFVSEVRRVAAALKWNRFSLLGHSFGGAVGGMFSCIFPEMVDKLILLESLPFVLDTNSILGLRGCAAEWRVRLGEELGPRPPSRTHGPLGDGQLADLQAEGHRARAAGGGLQEARAGGQPGRDAAEVSGRWDRWESEIWGSYGPPRGEVSGAWRKLHLLVPNLQHTCFSVCSLALLSHPGWDFVCPHSPHPVAVPFAPPLHKLSATPSTPPHTDTRTLTALRQTSPLVQARVLGRWPSRTFLSFHLGPRPRPRHPVSPLPQVTEKEQPRRRGVREASPAERNHTGGHGCVAEQRSEDHLGRALPRFRQQGAVYALHQKSAGPRPARQSEAIRHLRDPQPVEHPSRGLRCHPCSTAFSLDLGPGRNCDFRGLVCRAQGFRRQGLMGGKSQPQGGTLRTLWDI", "length": 479 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2BGU9-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "serhl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPAFMSLRHFTTTTMRRAASEFRMPVPWGELRGQVWGPSHGRPVLCLHGWADNSGTFNTLVPLLPNDWRFVAIDFPGHGLSSHRPDGCFYAFPFYVADVRRVVEALQWKRFSIIGHSMGGNVAGMFSALYPEMVESVVLLDTYGFLPTEVTDMFTNMRKGINDQIQYDNMANERKERVYTYEKAKERLKVANPYLSDQSADILLERAVREVDGGFVFTRDFRINLKNIIYINIDQCLHVLSQVKAKVMLLLAKDGLFKTFTLPDGYADRICKSWTDQKATFVEVEGDHHVHLNNPEAVSSVITDFLQPQSPDQTESQSGNQTSRL", "length": 326 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A071-1", "protein_name": "Serine hydrolase-like 2", "gene_name": "Serhl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPLAYSSRWSRHSSPSPLGLLSELKLAVPWGHIAVKVWGLQKNPPVLCLHGWLDNANSFDKLIPFLPKDFCYVAMDFGGHGLSTHYSPGLPYYHHNFVSEVRRVVSAFKWTRLSLLGHSFGGVVGGLFACMFPEMVDKLILLDSTPLLMDLNEVENIMTYRRKNIEQTLKVEDSQKPPGIFSPEEMLHELLTKNSHLNEDCGELLLQRGTTKVAEGLVLNRDQRLSWPQYSFDFMGKELTMHSLRRLQASVLIIKALDGYYDVRRENDLNKASFLLMLDILRSTLKERFQFVEIPGNHYIHMNKPQIVADIIRSFLQGPPRTTPSRL", "length": 328 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O18391-1", "protein_name": "Probable serine hydrolase", "gene_name": "kraken", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQTRVAATTAAQSPAAELSPETNGQTEEPLQLLGEDSWEEFSIAVPWGTVEAKWWGSKERQPIIALHGWQDNCGSFDRLCPLLPADTSILAIDLPGHGKSSHYPMGMQYFIFWDGICLIRRIVRKYNWKNVTLLGHSLGGALTFMYAASFPTEVEKLINIDIAGPTVRGTQRMAEGTGRALDKFLDYETLPESKQPCYSYDEMIKLVLDAYDGSVDEPSVRVLMNRGMRHNPSKNGYLFARDLRLKVSLLGMFTAEQTLAYARQIRCRVLNIRGIPGMKFETPQVYADVIATLRENAAKVVYVEVPGTHHLHLVTPDRVAPHIIRFLKEA", "length": 331 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q54M29-1", "protein_name": "Serine hydrolase-like protein DDB_G0286239", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNTNNNFSNGEEVSIHIGTGIDIAAKAWGPKESSQKMLALHGWLDNANTFDFIAPILAEKGIRIIAIDFIGHGLSPHKPSWCNLYYTDYITQVLDVAEALQWKTFSIMGHSMGAGIASIVAASMPHLVERIICLDFIGILSKEQDQIKAIQFAMQTRTTINNRKPHLYNNKQAIFDKLKANNPWIKDEAGQRLLDRSIESVISPTTGEQCYKLRHDPRLVGPSIFIMREAEVLLMLDEIQCPVLLIWGTTSSQQFQIKKNWTQIMEGRMSHIKNLKQLVVPGSHHFHMENTSAFSQDILEFMFEEKDLSFTPSSTTQQQQQQQQSAENKKGDNHNQIAEQDLSTSNTSSPIISKPKPNL", "length": 359 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9EPB5-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "Serhl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLHSELKLAVPWGHIALKVWGSQKNPPVLCLHGWLDNANSFDRLIPLLPQDFCYMAMDFGGHGLSSHYNPGLPYYQQNFVSEVRRVATAFKWNQFTLLGHSFGGCVGGTFACMFPEMVDKLILLDSTPFFLDSNEMENILTYRRRNIEHTLQVEASQKKSLRAVSPEEMLQGFLNNNSHLDKDCGELILQRGTTKVDAGLVLNRDRRISWPENSFDFVSKEMFVHSAKSLQASVLMIKALQGYYDVRRANDADKAPMHFMVDTLRSTLKERFQFVEVPGNHYIHMNKPQVVAGVVGPFLQGLQRMTSARL", "length": 311 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4I8-1", "protein_name": "Serine hydrolase-like protein 2", "gene_name": "SERHL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTFVSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVEASQEPSHVFSLKQLLQRLLKSNSHLSEECGELLLQRGTTKVATGLVLNRDQRLAWAENSIDFISRELCAHSIRKLQAHVLLIKAVHGYFDSRQNYSEKESLSFMIDTMKSTLKEQFQFVEVPGNHCVHMSEPQHVASIISSFLQCTHMLPAQL", "length": 314 }, "evidence": [ { "id": "F1NJK4", "url": "https://omabrowser.org/oma/group/F1NJK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "F1NJK4", "url": "https://www.uniprot.org/uniprotkb/F1NJK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NJK4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 303, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NJK4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NJK4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NKZ5-1", "uniprot_ac": "F1NKZ5", "uniprot_id": "F1NKZ5_CHICK", "mass": { "chemical_mass": 17898.0, "monoisotopic_mass": 17898.0 }, "refseq": { "ac": "XP_415407", "name": "protein CutA homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415407" }, "gene_names": [ { "name": "CUTAL", "type": "recommended", "evidence": [ { "id": "F1NKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5" } ] }, { "name": "CUTAL", "type": "synonym", "evidence": [ { "id": "XP_415407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415407" } ] } ], "protein_names": [ { "name": "Protein CutA homolog", "type": "recommended", "evidence": [ { "id": "F1NKZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5/entry#names_and_taxonomy" } ] }, { "name": "protein CutA homolog", "type": "synonym", "evidence": [ { "id": "XP_415407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415407" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415407.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415407" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NKZ5", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CUTAL", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5", "locus": {} } ], "crossref": [ { "id": "F1NKZ5", "url": "https://alphafold.ebi.ac.uk/entry/F1NKZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001620", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417124", "url": "https://www.ncbi.nlm.nih.gov/gene/417124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417124", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARGIMDK", "url": "https://omabrowser.org/oma/group/ARGIMDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AGU8", "url": "https://www.orthodb.org/?gene=A0A8V1AGU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NKZ5", "url": "https://www.orthodb.org/?gene=F1NKZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23419:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23419:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AGU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKZ5", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NKZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALGPRCPLPTAQGCPRPGCRTVLLAMTLSLLMYPMLRSLALQLHSAITGSYVSGTHSVVFINCLNEQIAKDIARGIMDKKLAAYVNILPKSSALYFWKGELEESTEILLLVKTRTSKISELSNYVRSIHPFEIPEVISLPIDQGNPLYLKWIGENVPRD", "length": 161, "header": "tr|F1NKZ5-1|F1NKZ5_CHICK Isoform 1 of Protein CutA homolog OS=Gallus gallus OX=9031 GN=CUTAL PE=3 SV=4 CANONICAL=F1NKZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AGU8-1", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5/entry#A0A8V1AGU8-1", "sequence": { "sequence": "MLILNHKCSWGFPRHMHIHLPRRLMIAVLNRSEFALSRECDYILIQRSRYNSVSQPGLWLWEKLVGFAAQQIFSGFMGKNTSSKNDCEEPRAIKEYFLKWTEKRRQLIQSISHFPSGKVFLSVWCQDVKAMTLSLLMYPMLRSLALQLHSAITGSYVSGTHSVVFINCLNEQIAKDIARGIMDKKLAAYVNILPKSSALYFWKGELEESTEILLLVKTRTSKISELSNYVRSIHPFEIPEVISLPIDQGNPLYLKWIGENVPRD", "length": 264, "header": "tr|A0A8V1AGU8-1|F1NKZ5_CHICK Computationally mapped isoform of Protein CutA homolog OS=Gallus gallus OX=9031 GN=CUTAL PE=3 SV=1 CANONICAL=F1NKZ5-1" }, "locus": { "chromosome": "17", "start_pos": 8894202, "end_pos": 8888825, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066669.1", "url": "https://www.ensembl.org/id/ENSGALT00010066669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040817.1", "url": "https://www.ensembl.org/id/ENSGALP00010040817.1" } ] } }, { "isoform_ac": "F1NKZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5/entry#F1NKZ5-1", "sequence": { "sequence": "MEALGPRCPLPTAQGCPRPGCRTVLLAMTLSLLMYPMLRSLALQLHSAITGSYVSGTHSVVFINCLNEQIAKDIARGIMDKKLAAYVNILPKSSALYFWKGELEESTEILLLVKTRTSKISELSNYVRSIHPFEIPEVISLPIDQGNPLYLKWIGENVPRD", "length": 161, "header": "tr|F1NKZ5-1|F1NKZ5_CHICK Isoform 1 of Protein CutA homolog OS=Gallus gallus OX=9031 GN=CUTAL PE=3 SV=4 CANONICAL=F1NKZ5-1" }, "locus": { "chromosome": "17", "start_pos": 8894202, "end_pos": 8888156, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010066670.1", "url": "https://www.ensembl.org/id/ENSGALT00010066670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010040818.1", "url": "https://www.ensembl.org/id/ENSGALP00010040818.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9RXG9-1", "protein_name": "Protein CutA homolog", "gene_name": "CUTAL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDRLGSRCPLPGSTRPSIFICLLILTASLLTYPVLRTLSLQFLSVLTGSYVSGTYSIVFVNCPNEQIARDVARAILDKKLAASVNILPKASSLYYWNGEIEEATEVLLLIKTKTSKIHMLSSYIRLVHPFEIPELFSLPMDQGDVHYLKWLEEGMEEE", "length": 158 }, "evidence": [ { "id": "F1NKZ5", "url": "https://omabrowser.org/oma/group/F1NKZ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "F1NKZ5", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to metal ion", "id": "GO:0010038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010038", "evidence": [ { "database": "UniProtKB", "id": "F1NKZ5", "url": "https://www.uniprot.org/uniprotkb/F1NKZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NIC7-1", "uniprot_ac": "F1NIC7", "uniprot_id": "F1NIC7_CHICK", "mass": { "chemical_mass": 33684.0, "monoisotopic_mass": 33684.0 }, "refseq": { "ac": "XP_040502365", "name": "store-operated calcium entry regulator STIMATE-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502365" }, "gene_names": [ { "name": "LOC121106612", "type": "recommended", "evidence": [ { "id": "F1NIC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ] }, { "name": "LOC121106612", "type": "synonym", "evidence": [ { "id": "XP_040502365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502365" } ] } ], "protein_names": [ { "name": "STIM activating enhancer", "type": "synonym", "evidence": [ { "id": "F1NIC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NIC7/entry#names_and_taxonomy" } ] }, { "name": "store-operated calcium entry regulator STIMATE-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040502365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502365" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040502365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502365" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106612", "url": "https://www.uniprot.org/uniprotkb/F1NIC7", "locus": {} } ], "crossref": [ { "id": "F1NIC7", "url": "https://alphafold.ebi.ac.uk/entry/F1NIC7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001720", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001720", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "121106612", "url": "https://www.ncbi.nlm.nih.gov/gene/121106612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LNCFQYF", "url": "https://omabrowser.org/oma/group/LNCFQYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1NIC7", "url": "https://www.orthodb.org/?gene=F1NIC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31735", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31735", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31735:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31735:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040502365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502365", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1A794", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A794", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A794-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A794-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJ85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIC7-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVTPPNCSLGAALSPQPGAGPAAGPGERGCENGALMDSFGIFLQGLLGVLAFSILMLKRLREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLSDLTEEDPCSLYFINFLLDATLGMLLIYAGIRAVSSIVEWQQWESLRFGEYGDPLQCSAWMGQCALYIMIMTFEKTIIIIVLLIPQWKEVALLNPIENPQLELAIVMLIVPFFVNAFIFWVVDNFLMKKGKTKAKLEEKEAGQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTNLKPIKKKKHRFGLPV", "length": 298, "header": "tr|F1NIC7-1|F1NIC7_CHICK Isoform 1 of STIM activating enhancer OS=Gallus gallus OX=9031 GN=LOC121106612 PE=4 SV=3 CANONICAL=F1NIC7-1" }, "isoforms": [ { "isoform_ac": "A0A8V1A794-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC7/entry#A0A8V1A794-1", "sequence": { "sequence": "MGVTPPNCSLGAALSPQPGAGPAAGPGERGCENGALMDSFGIFLQGLLGVLAFSILMLKRLREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLSDLTEEDPCSLYFINFLLDATLGMLLIYAGIRAVSSIVEWQQWESLRFGEYGDPLQCSAWMGQCALYIMIMTFEKTIIIIVLLIPQWKEAFIFWVVDNFLMKKGKTKAKLEEKEAGQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTNLKPIKKKKHRFGLPV", "length": 272, "header": "tr|A0A8V1A794-1|A0A8V1A794_CHICK Computationally mapped isoform of STIM activating enhancer OS=Gallus gallus OX=9031 GN=LOC121106612 PE=4 SV=1 CANONICAL=F1NIC7-1" }, "locus": { "chromosome": "12", "start_pos": 940666, "end_pos": 914530, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068065.1", "url": "https://www.ensembl.org/id/ENSGALT00010068065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041808.1", "url": "https://www.ensembl.org/id/ENSGALP00010041808.1" } ] } }, { "isoform_ac": "A0A8V1AHE0-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC7/entry#A0A8V1AHE0-1", "sequence": { "sequence": "MLFIHFANVYLSDLTEEDPCSLYFINFLLDATLGMLLIYAGIRAVSSIVEWQQWESLRFGDPLQCSAWMGQCALYIMIMTFEKTIIIIVLLIPQWKEVALLNPIENPQLELAIVMLIVPFFVNAFIFWVVDNFLMKKGKTKAKLEEKEAGQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTNLKPIKKKKHRFGLPV", "length": 211, "header": "tr|A0A8V1AHE0-1|F1NIC7_CHICK Computationally mapped isoform of STIM activating enhancer OS=Gallus gallus OX=9031 GN=LOC121106612 PE=4 SV=1 CANONICAL=F1NIC7-1" }, "locus": { "chromosome": "12", "start_pos": 926405, "end_pos": 914530, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068063.1", "url": "https://www.ensembl.org/id/ENSGALT00010068063.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041806.1", "url": "https://www.ensembl.org/id/ENSGALP00010041806.1" } ] } }, { "isoform_ac": "A0A8V1AJ85-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC7/entry#A0A8V1AJ85-1", "sequence": { "sequence": "MSLAFAMQCFCCFIGKINLVSKSYIEFQSSLNRQCESTLGLPLPCSSFCTKRNSFMCFLHLSEVKRLREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLSDLTEEDPCSLYFINFLLDATLGMLLIYAGIRAVSSIVEWQQWESLRFGEYGDPLQCSAWMGQCALYIMIMTFEKTIIIIVLLIPQWKEVALLNPIENPQLELAIVMLIVPFFVNAFIFWVVDNFLMKKGKTKAKLEEKEAGQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTNLKPIKKKKHRFGLPV", "length": 304, "header": "tr|A0A8V1AJ85-1|F1NIC7_CHICK Computationally mapped isoform of STIM activating enhancer OS=Gallus gallus OX=9031 GN=LOC121106612 PE=4 SV=1 CANONICAL=F1NIC7-1" }, "locus": { "chromosome": "12", "start_pos": 933535, "end_pos": 914530, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068061.1", "url": "https://www.ensembl.org/id/ENSGALT00010068061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041804.1", "url": "https://www.ensembl.org/id/ENSGALP00010041804.1" } ] } }, { "isoform_ac": "F1NIC7-1", "url": "https://www.uniprot.org/uniprotkb/F1NIC7/entry#F1NIC7-1", "sequence": { "sequence": "MGVTPPNCSLGAALSPQPGAGPAAGPGERGCENGALMDSFGIFLQGLLGVLAFSILMLKRLREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLSDLTEEDPCSLYFINFLLDATLGMLLIYAGIRAVSSIVEWQQWESLRFGEYGDPLQCSAWMGQCALYIMIMTFEKTIIIIVLLIPQWKEVALLNPIENPQLELAIVMLIVPFFVNAFIFWVVDNFLMKKGKTKAKLEEKEAGQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTNLKPIKKKKHRFGLPV", "length": 298, "header": "tr|F1NIC7-1|F1NIC7_CHICK Isoform 1 of STIM activating enhancer OS=Gallus gallus OX=9031 GN=LOC121106612 PE=4 SV=3 CANONICAL=F1NIC7-1" }, "locus": { "chromosome": "12", "start_pos": 940666, "end_pos": 914530, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068064.1", "url": "https://www.ensembl.org/id/ENSGALT00010068064.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010041807.1", "url": "https://www.ensembl.org/id/ENSGALP00010041807.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VHF7-1", "protein_name": "STIM activating enhancer", "gene_name": "STIMATE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGPAGNTSRALPGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLLLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGRTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPAKKKKHRFGLPV", "length": 294 }, "evidence": [ { "id": "F1NIC7", "url": "https://omabrowser.org/oma/group/F1NIC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6RY84-1", "protein_name": "STIM activating enhancer", "gene_name": "STIMATE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQGPAGNSSHSLTGGPPSTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLNEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGRTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRRLTPLKPAKKKKHRFGLPV", "length": 294 }, "evidence": [ { "id": "F1NIC7", "url": "https://omabrowser.org/oma/group/F1NIC7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q12042-1", "protein_name": "Vacuolar membrane protein YPL162C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYVSNGKDTCQLLGPVSLFVQTLMGMTAVIVLLVKRNYEHPRRKMIVWSYDIGKQIIGSLGIHFLNLGISILKKRRRSLFAITAKGNDDEDQCDWYFLNLLLDTTVGIPILWLCLYIIEKVLKSLHFQNIESGNYFPSKTVGSHPRKPLFSAFVKQLLIFIVGLGVMKFCVFLILNYLEDLAYWFADLILGWSDSWPNFQVFLVMFVFPILLNCFQYFCVDNVIRLHSESLTITNAENFETNTFLNDEIPDLSEVSNEVPNKDNNISSYGSII", "length": 273 }, "evidence": [ { "id": "F1NIC7", "url": "https://omabrowser.org/oma/group/F1NIC7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UF25-1", "protein_name": "Store-operated calcium entry regulator STIMATE", "gene_name": "Stimate", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGPGGNVSRGLPSGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLRRPVKKKHRFGLPV", "length": 288 }, "evidence": [ { "id": "F1NIC7", "url": "https://omabrowser.org/oma/group/F1NIC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSW6-1", "protein_name": "Store-operated calcium entry regulator STIMATE", "gene_name": "Stimate", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGPGGNVSRGLPGGPASTVASGAGRCESGALMHSFGIFLQGLLGVVAFSTLMLKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVGVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNAFMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDAEEDLRRPVKKKHRFGLPV", "length": 288 }, "evidence": [ { "id": "F1NIC7", "url": "https://omabrowser.org/oma/group/F1NIC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ], "pmid": "" }, { "name": "cortical endoplasmic reticulum", "id": "GO:0032541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032541", "evidence": [ { "database": "UniProtKB", "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane contact site", "id": "GO:0140268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140268", "evidence": [ { "database": "UniProtKB", "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "store-operated calcium entry", "id": "GO:0002115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002115", "evidence": [ { "database": "UniProtKB", "id": "F1NIC7", "url": "https://www.uniprot.org/uniprotkb/F1NIC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 242, "end_pos": 244 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C5G4-1", "uniprot_ac": "E1C5G4", "uniprot_id": "E1C5G4_CHICK", "mass": { "chemical_mass": 65852.0, "monoisotopic_mass": 65852.0 }, "refseq": { "ac": "XP_003642349", "name": "ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642349" }, "gene_names": [ { "name": "RALGPS1", "type": "recommended", "evidence": [ { "id": "E1C5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5G4" } ] }, { "name": "RALGPS1", "type": "synonym", "evidence": [ { "id": "XP_003642349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642349" } ] } ], "protein_names": [ { "name": "Ras-specific guanine nucleotide-releasing factor RalGPS1", "type": "recommended", "evidence": [ { "id": "E1C5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#names_and_taxonomy" } ] }, { "name": "Ral GEF with PH domain and SH3-binding motif 1", "type": "synonym", "evidence": [ { "id": "E1C5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#names_and_taxonomy" } ] }, { "name": "Ral guanine nucleotide exchange factor 2", "type": "synonym", "evidence": [ { "id": "E1C5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#names_and_taxonomy" } ] }, { "name": "RalA exchange factor RalGPS1", "type": "synonym", "evidence": [ { "id": "E1C5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#names_and_taxonomy" } ] }, { "name": "ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_003642349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642349" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642349" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5G4", "url": "https://www.uniprot.org/uniprotkb/E1C5G4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RALGPS1", "url": "https://www.uniprot.org/uniprotkb/E1C5G4", "locus": { "chromosome": "17", "start_pos": 10969020, "end_pos": 10883511, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028692", "url": "https://www.ensembl.org/id/ENSGALG00010028692" } ] } } ], "crossref": [ { "id": "E1C5G4", "url": "https://alphafold.ebi.ac.uk/entry/E1C5G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000906", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000906", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13310", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13310", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417089", "url": "https://www.ncbi.nlm.nih.gov/gene/417089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417089", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417089", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q2TXA0", "url": "https://www.orthodb.org/?gene=A0A3Q2TXA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U2R4", "url": "https://www.orthodb.org/?gene=A0A3Q2U2R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AHH2", "url": "https://www.orthodb.org/?gene=A0A8V1AHH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1ALH7", "url": "https://www.orthodb.org/?gene=A0A8V1ALH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C5G4", "url": "https://www.orthodb.org/?gene=E1C5G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1C5G4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1C5G4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_003642349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXA0", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TXA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TXA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2R4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U2R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AHH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1ALH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5G4", "url": "https://www.uniprot.org/uniprotkb/E1C5G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5G4-1", "url": "https://www.uniprot.org/uniprotkb/E1C5G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYKRNDFMANVMVTSATPEGSSSSDSLEGRSSDYANKSYDAVVFDVLKVTPEEFASQITLMDMPVFKAIQPEELASCGWNKKEKHILAPNIVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKTAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKATFEKLDYLLSKEDNYKRTREYIRSLKMVPSIPYLGIYLFDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCNYEHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGNSSPRLVSSKEDLTGPAEVSAVMKFSRRPTCPDTSVAASLSTPPIPRHRKSHSLGNNMMCQFSVVESKSATFPTERPRHLLDDSVLESQSPTRSDMLNSLFTNGISIDSSESSEFSEEQSSGLERGRLYATLGPNWRVPIRNSPRSRSCVYSPTGACSCTLGSSMGVVTMEGPLRRKTLLKEGKKPTLSSWTRYWIMLSGSNLLYFGAKSLRGNERKHYKSTPSKKISIVGWMVALPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNKPQAPANLMSFE", "length": 582, "header": "tr|E1C5G4-1|E1C5G4_CHICK Isoform 1 of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=4 SV=1 CANONICAL=E1C5G4-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TXA0-1", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#A0A3Q2TXA0-1", "sequence": { "sequence": "MYKRNDFMANVMVTSATPEGSSSSDSLEGRSSDYANKSYDAVVFDVLKVTPEEFASQITLMDMPVFKAIQPEELASCGWNKKEKHILAPNIVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKTAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKATFEKLDYLLSKEDNYKRTREYIRSLKMVPSIPYLGIYLFDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCNYEHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGNSSPRLVSSKEDLTGPAEVSAVMKFSRRPTCPDTSVAASLSTPPIPRHRKSHSLGNNMMCQFSVVESKSATFPTERPRHLLDDSVLESQSPTRSDMLNSLFTNGISIDSSESSEFSEEQSSGLERGRLYATLGPNWRVPIRNSPRSRSCVYSPTGACSCTLGSSMGVVTMEGPLRRKTLLKEGKKPTLSSWTRYWIMLSGSNLLYFGAKSLRGNERKHYKSTPSKKISIVGWMVALPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNKPQVD", "length": 575, "header": "tr|A0A3Q2TXA0-1|A0A3Q2TXA0_CHICK Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=4 SV=1 CANONICAL=E1C5G4-1" }, "locus": { "chromosome": "17", "start_pos": 10968222, "end_pos": 10896877, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069462.1", "url": "https://www.ensembl.org/id/ENSGALT00010069462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042777.1", "url": "https://www.ensembl.org/id/ENSGALP00010042777.1" } ] } }, { "isoform_ac": "A0A3Q2U2R4-1", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#A0A3Q2U2R4-1", "sequence": { "sequence": "MSAELPYSGSSSSDSLEGRSSDYANKSYDAVVFDVLKVTPEEFASQITLMDMPVFKAIQPEELASCGWNKKEKHILAPNIVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKTAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKATFEKLDYLLSKEDNYKRTREYIRSLKMVPSIPYLGIYLFDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCNYEHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGNSSPRLVSSKEDLTGPAEVSAVMKFSRRPTCPDTSVAASLSTPPIPRHRKSHSLGNNMMCQFSVVESKSATFPTERPRHLLDDSVLESQSPTRSDMLNSLFTNGISIDSSESSEFSEEQSSGLERGRLYATLGPNWRVPIRNSPRSRSCVYSPTGACSCTLGSSMGVVTMEGPLRRKTLLKEGKKPTLSSWTRYWIMLSGSNLLYFGAKSLRGNERKHYKSTPSKKISIVGWMVALPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNKPQVRLANRLYLLLHILQKTRNRRYFF", "length": 586, "header": "tr|A0A3Q2U2R4-1|A0A3Q2U2R4_CHICK Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=4 SV=1 CANONICAL=E1C5G4-1" }, "locus": { "chromosome": "17", "start_pos": 10965770, "end_pos": 10887963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069466.1", "url": "https://www.ensembl.org/id/ENSGALT00010069466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042779.1", "url": "https://www.ensembl.org/id/ENSGALP00010042779.1" } ] } }, { "isoform_ac": "A0A8V1AHH2-1", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#A0A8V1AHH2-1", "sequence": { "sequence": "MYKRNDFMANVMVTSATPEGSSSSDSLEGRSSDYANKSYDAVVFDVLKVTPEEFASQITLMDMPVFKAIQPEELASCGWNKKEKHILAPNIVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKTAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKATFEKLDYLLSKEDNYKRTREYIRSLKMVPRIYLFDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCNYEHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGNSSPRLVSSKEDLTGPAEVSAVMKFSRRPTCPDTSVAASLSTPPIPRHRKSHSLGNNMMCQFSVVESKSATFPTERPRHLLDDSVLESQSPTRSDMLNSLFTNGISIDSSESSEFSEEQSSGLERGRLYATLGPNWRVPIRNSPRSRSCVYSPTGACSCTLGSSMGVVTMEGPLRRKTLLKEGKKPTLSSWTRYWIMLSGSNLLYFGAKSLRGNERKHYKSTPSKKISIVGWMVALPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNKPQVRLANRLYLLLHILQKTRNRRYFF", "length": 592, "header": "tr|A0A8V1AHH2-1|E1C5G4_CHICK Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=4 SV=1 CANONICAL=E1C5G4-1" }, "locus": { "chromosome": "17", "start_pos": 10965770, "end_pos": 10896877, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069460.1", "url": "https://www.ensembl.org/id/ENSGALT00010069460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042776.1", "url": "https://www.ensembl.org/id/ENSGALP00010042776.1" } ] } }, { "isoform_ac": "A0A8V1ALH7-1", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#A0A8V1ALH7-1", "sequence": { "sequence": "MYKRNDFMANVMVTSATPEGSSSSDSLEGRSSDYANKSYDAVVFDVLKVTPEEFASQITLMDMPVFKAIQPEELASCGWNKKEKHILAPNIVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKTAKLLNRKDKATFEKLDYLLSKEDNYKRTREYIRSLKMVPSIPYLGIYLFDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCNYEHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGNSSPRLVSSKEDLTGPAEVSAVMKFSRRPTCPDTSVAASLSTPPIPRHRKSHSLGNNMMCQFSVVESKSATFPTERPRHLLDDSVLESQSPTRSDMLNSLFTNGISIDSSESSEFSEEQSSGLERGRLYATLGPNWRVPIRNSPRSRSCVYSPTGACSCTLGSSMGVVTMEGPLRRKTLLKEGKKPTLSSWTRYWIMLSGSNLLYFGAKSLRGNERKHYKSTPSKKISIVGWMVALPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNKPQVRLANRLYLLLHILQKTRNRRYFF", "length": 566, "header": "tr|A0A8V1ALH7-1|E1C5G4_CHICK Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=4 SV=1 CANONICAL=E1C5G4-1" }, "locus": { "chromosome": "17", "start_pos": 10965770, "end_pos": 10896877, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069464.1", "url": "https://www.ensembl.org/id/ENSGALT00010069464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042778.1", "url": "https://www.ensembl.org/id/ENSGALP00010042778.1" } ] } }, { "isoform_ac": "E1C5G4-1", "url": "https://www.uniprot.org/uniprotkb/E1C5G4/entry#E1C5G4-1", "sequence": { "sequence": "MYKRNDFMANVMVTSATPEGSSSSDSLEGRSSDYANKSYDAVVFDVLKVTPEEFASQITLMDMPVFKAIQPEELASCGWNKKEKHILAPNIVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKTAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKATFEKLDYLLSKEDNYKRTREYIRSLKMVPSIPYLGIYLFDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCNYEHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGNSSPRLVSSKEDLTGPAEVSAVMKFSRRPTCPDTSVAASLSTPPIPRHRKSHSLGNNMMCQFSVVESKSATFPTERPRHLLDDSVLESQSPTRSDMLNSLFTNGISIDSSESSEFSEEQSSGLERGRLYATLGPNWRVPIRNSPRSRSCVYSPTGACSCTLGSSMGVVTMEGPLRRKTLLKEGKKPTLSSWTRYWIMLSGSNLLYFGAKSLRGNERKHYKSTPSKKISIVGWMVALPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNKPQAPANLMSFE", "length": 582, "header": "tr|E1C5G4-1|E1C5G4_CHICK Isoform 1 of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus OX=9031 GN=RALGPS1 PE=4 SV=1 CANONICAL=E1C5G4-1" }, "locus": { "chromosome": "17", "start_pos": 10966691, "end_pos": 10896877, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069459.1", "url": "https://www.ensembl.org/id/ENSGALT00010069459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042775.1", "url": "https://www.ensembl.org/id/ENSGALP00010042775.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417089", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417089", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of Ral protein signal transduction", "id": "GO:0032485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032485", "evidence": [ { "database": "UniProtKB", "id": "E1C5G4", "url": "https://www.uniprot.org/uniprotkb/E1C5G4" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "E1C5G4", "url": "https://www.uniprot.org/uniprotkb/E1C5G4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C5G4", "url": "https://www.uniprot.org/uniprotkb/E1C5G4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C5G4", "url": "https://www.uniprot.org/uniprotkb/E1C5G4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E1C5G4", "url": "https://www.uniprot.org/uniprotkb/E1C5G4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C745-1", "uniprot_ac": "E1C745", "uniprot_id": "E1C745_CHICK", "mass": { "chemical_mass": 13537.0, "monoisotopic_mass": 13537.0 }, "refseq": { "ac": "NP_001243435", "name": "BLOC-1-related complex subunit 8 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243435" }, "gene_names": [ { "name": "BORCS8", "type": "recommended", "evidence": [ { "id": "E1C745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C745" } ] }, { "name": "BORCS8", "type": "synonym", "evidence": [ { "id": "NP_001243435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243435" } ] }, { "name": "MEF2BNB", "type": "synonym", "evidence": [ { "id": "NP_001243435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243435" } ] } ], "protein_names": [ { "name": "BLOC-1 related complex subunit 8", "type": "synonym", "evidence": [ { "id": "E1C745", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C745/entry#names_and_taxonomy" } ] }, { "name": "BLOC-1-related complex subunit 8 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001243435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243435" } ] }, { "name": "MEF2B neighbor", "type": "synonym", "evidence": [ { "id": "NP_001243435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243435" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01000356.1, BU491282.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000376.1. Transcript Variant: This variant (1) encodes the longer isoform (1).", "evidence": [ { "database": "RefSeq", "id": "NP_001243435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243435" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C745", "url": "https://www.uniprot.org/uniprotkb/E1C745" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BORCS8", "url": "https://www.uniprot.org/uniprotkb/E1C745", "locus": { "chromosome": "28", "start_pos": 4025913, "end_pos": 4017954, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028439", "url": "https://www.ensembl.org/id/ENSGALG00010028439" } ] } } ], "crossref": [ { "id": "E1C745", "url": "https://alphafold.ebi.ac.uk/entry/E1C745", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014581", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014581", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "426622", "url": "https://www.ncbi.nlm.nih.gov/gene/426622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426622", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426622", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SMMNHAR", "url": "https://omabrowser.org/oma/group/SMMNHAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR21146", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21146", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21146:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21146:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1C745", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1C745", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001243435", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243435", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PFH6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PFH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PFH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AIL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIL9-1", "database": 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127, "header": "tr|A0A8V1AIL9-1|E1C745_CHICK Computationally mapped isoform of BLOC-1 related complex subunit 8 OS=Gallus gallus OX=9031 GN=BORCS8 PE=3 SV=1 CANONICAL=E1C745-1" }, "locus": { "chromosome": "28", "start_pos": 4025227, "end_pos": 4018899, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068881.1", "url": "https://www.ensembl.org/id/ENSGALT00010068881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042323.1", "url": "https://www.ensembl.org/id/ENSGALP00010042323.1" } ] } }, { "isoform_ac": "A0A8V1AKF3-1", "url": "https://www.uniprot.org/uniprotkb/E1C745/entry#A0A8V1AKF3-1", "sequence": { "sequence": "MEEPEMQLKVKKVTDKFTESMYVLANEPSVALYRLQEHVRRSLPELAQHKSDMQSWEEQSQGAIYTVEYACSAIKSMTDSSVYFKSIDSLLKHAIAMKDQLNAAQGRSDLLALFTHEKQIILFTERDKWKIIYFLIERGMFGSVIH", "length": 146, "header": "tr|A0A8V1AKF3-1|E1C745_CHICK Computationally mapped isoform of BLOC-1 related complex subunit 8 OS=Gallus gallus OX=9031 GN=BORCS8 PE=3 SV=1 CANONICAL=E1C745-1" }, "locus": { "chromosome": "28", "start_pos": 4024483, "end_pos": 4017997, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068879.1", "url": "https://www.ensembl.org/id/ENSGALT00010068879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042321.1", "url": "https://www.ensembl.org/id/ENSGALP00010042321.1" } ] } }, { "isoform_ac": "E1C745-1", "url": "https://www.uniprot.org/uniprotkb/E1C745/entry#E1C745-1", "sequence": { "sequence": "MEEPEMQLKVKKVTDKFTESMYVLANEPSVALYRLQEHVRRSLPELAQHKSDMQSWEEQSQGAIYTVEYACSAIKSMTDSSVYFKSIDSLLKHAIAMKDQLNAAQGRSAVAPQAKNPPGSS", "length": 121, "header": "tr|E1C745-1|E1C745_CHICK Isoform 1 of BLOC-1 related complex subunit 8 OS=Gallus gallus OX=9031 GN=BORCS8 PE=3 SV=1 CANONICAL=E1C745-1" }, "locus": { "chromosome": "28", "start_pos": 4025227, "end_pos": 4017997, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010068884.1", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1NDA6-1", "uniprot_ac": "F1NDA6", "uniprot_id": "F1NDA6_CHICK", "mass": { "chemical_mass": 53410.0, "monoisotopic_mass": 53410.0 }, "refseq": { "ac": "NP_989706", "name": "solute carrier family 2, facilitated glucose transporter member 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" }, "gene_names": [ { "name": "SLC2A8", "type": "recommended", "evidence": [ { "id": "F1NDA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ] }, { "name": "GLUT8", "type": "synonym", "evidence": [ { "id": "NP_989706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ] }, { "name": "SLC2A8", "type": "synonym", "evidence": [ { "id": "NP_989706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ] } ], "protein_names": [ { "name": "Solute carrier family 2, facilitated glucose transporter member 8", "type": "recommended", "evidence": [ { "id": "F1NDA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDA6/entry#names_and_taxonomy" } ] }, { "name": "Glucose transporter type 8", "type": "synonym", "evidence": [ { "id": "F1NDA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDA6/entry#names_and_taxonomy" } ] }, { "name": "Glucose transporter type X1", "type": "synonym", "evidence": [ { "id": "F1NDA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDA6/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 2 (facilitated glucose transporter), member 8", "type": "synonym", "evidence": [ { "id": "NP_989706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ] }, { "name": "solute carrier family 2, (facilitated glucose transporter) member 8", "type": "synonym", "evidence": [ { "id": "NP_989706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ] }, { "name": "solute carrier family 2, facilitated glucose transporter member 8", "type": "synonym", "evidence": [ { "id": "NP_989706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01007751.1, HAEK01016043.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000308.1. On Sep 23, 2021 this sequence version replaced NP_989706.1.", "evidence": [ { "database": "RefSeq", "id": "NP_989706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ] }, { "annotation": "GLUT8 was identified in chickens. GLUT8 was composed of 1449 bp with a coding region for a 482 amino acid protein.", "evidence": [ { "database": "RefSeq", "id": "NP_989706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" }, { "database": "PubMed", "id": "12899849", "url": "https://glygen.org/publication/PubMed/12899849" } ] }, { "annotation": "Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate.", "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6#function" }, { "database": "UniProtKB", "id": "ARBA00059062", "url": "https://www.uniprot.org/uniprotkb/ARBA00059062#function" }, { "database": "UniProtKB", "id": "A0A8V1AA02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA02#function" } ] }, { "annotation": "The extent of mRNA expression of GLUT1, GLUT2, GLUT3 and GLUT8 in chickens intrinsically lacking GLUT4 is reported.", "evidence": [ { "database": "RefSeq", "id": "NP_989706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" }, { "database": "PubMed", "id": "16268111", "url": "https://glygen.org/publication/PubMed/16268111" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC2A8", "url": "https://www.uniprot.org/uniprotkb/F1NDA6", "locus": { "chromosome": "17", "start_pos": 11000754, "end_pos": 10991239, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028726", "url": "https://www.ensembl.org/id/ENSGALG00010028726" } ] } } ], "crossref": [ { "id": "F1NDA6", "url": "https://alphafold.ebi.ac.uk/entry/F1NDA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000853", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000853", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "378802", "url": "https://www.ncbi.nlm.nih.gov/gene/378802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:378802", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378802", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWIDYGT", "url": "https://omabrowser.org/oma/group/YWIDYGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AA02", "url": "https://www.orthodb.org/?gene=A0A8V1AA02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AJR0", "url": "https://www.orthodb.org/?gene=A0A8V1AJR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NDA6", "url": "https://www.orthodb.org/?gene=F1NDA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48021:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48021:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_989706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17629", "url": "https://www.rhea-db.org/rhea/17629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60372", "url": "https://www.rhea-db.org/rhea/60372", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60376", "url": "https://www.rhea-db.org/rhea/60376", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60380", "url": "https://www.rhea-db.org/rhea/60380", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V1AA02", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AA02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AA02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AJR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NDA6-1", "url": "https://www.uniprot.org/uniprotkb/F1NDA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEESQYLLAHRTSDAYLRVQNKKLYLATFAAVLGPLSFGFVLGYSSPAIPELRKIDNPKLRLDSNQASWFGSIVTLGAAAGGILGGYLVDKIGRKLSLMLCSIPFVSGYIVIISAQNVWMLYFGRILTGLASGITSLVVPVYISEISHTDVRGMLGSFVQLMVVTGILGAYIAGLTLKWHWLAVLCSFPPCVMLLFMLFMPETPRFLLDQKKRAEAIAALQFLRGPYVDHEWECRQIEANVEEEGLSLFEFKNPSIYRPLLIGVILMFLQQVTGINAVMFYAETIFEDANFQDSRMASVVVGFIQVCFTAVAALIIDKTGRKVLLYVSGMIMALSTALFGFYFKMVLPNGNNSSNTDLWFTLNSVTPGTDTRLSWLAVVSLGLFVAGFALGWGPVPWLVMSEIFPLKARGVSSSACVLTNWVMAFLVTKEFHDFIGFLTSYGTFWLFSAFCCLSVTFAAFYVPETKGRTLEQIEAYFRKS", "length": 482, "header": "tr|F1NDA6-1|F1NDA6_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 8 OS=Gallus gallus OX=9031 GN=SLC2A8 PE=3 SV=1 CANONICAL=F1NDA6-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AA02-1", "url": "https://www.uniprot.org/uniprotkb/F1NDA6/entry#A0A8V1AA02-1", "sequence": { "sequence": "MILVGIFHLRVQNKKLYLATFAAVLGPLSFGFVLGYSSPAIPELRKIDNPKLRLDSNQASWFGSIVTLGAAAGGILGGYLVDKIGRKLSLMLCSIPFVSGYIVIISAQNVWMLYFGRILTGLASGITSLVVPVYISEISHTDVRGMLGSFVQLMVVTGILGAYIAGLTLKWHWLAVLCSFPPCVMLLFMLFMPETPRFLLDQKKRAEAIAALQFLRGPYVDHEWECRQIEANVEEEGLSLFEFKNPSIYRPLLIGVILMFLQQVTGINAVMFYAETIFEDANFQDSRMASVVVGFIQVCFTAVAALIIDKTGRKVLLYVSGMIMALSTALFGFYFKMVLPNGNNSSNTDLWFTLNSVTPGTDTRLSWLAVVSLGLFVAGFALGWGPVPWLVMSEIFPLKARGVSSSACVLTNWVMAFLVTKEFHDFIGFLTSYGTFWLFSAFCCLSVTFAAFYVPETKGRTLEQIEAYFRKS", "length": 472, "header": "tr|A0A8V1AA02-1|A0A8V1AA02_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 8 OS=Gallus gallus OX=9031 GN=SLC2A8 PE=3 SV=1 CANONICAL=F1NDA6-1" }, "locus": { "chromosome": "17", "start_pos": 11000534, "end_pos": 10992003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069533.1", "url": "https://www.ensembl.org/id/ENSGALT00010069533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042797.1", "url": "https://www.ensembl.org/id/ENSGALP00010042797.1" } ] } }, { "isoform_ac": "A0A8V1AJR0-1", "url": "https://www.uniprot.org/uniprotkb/F1NDA6/entry#A0A8V1AJR0-1", "sequence": { "sequence": "MAAEESQYLLAHRTSDAYLRVQNKKLYLATFAAVLGPLSFGFVLGYSSPAIPELRKIDNPKLRLDSNQASWFGSIVTLGAAAGGILGGYLVDKIGRKLSLMLCSIPFVSGYIVIISAQNVWMLYFGRILTGLASGITSLVVPVYISEISHTDVRGMLGSFVQLMVVTGILGAYIAGLTLKWHWLAVLCSFPPCVMLLFMLFMPETPRFLLDQKKRAEAIAALQFLRGPYVDHEWECRQIEANVEEEDSRMASVVVGFIQVCFTAVAALIIDKTGRKVLLYVSGMIMALSTALFGFYFKMVLPNGNNSSNTDLWFTLNSVTPGTDTRLSWLAVVSLGLFVAGFALGWGPVPWLVMSEIFPLKARGVSSSACVLTNWVMAFLVTKEFHDFIGFLTSYGTFWLFSAFCCLSVTFAAFYVPETKGRTLEQIEAYFRKS", "length": 434, "header": "tr|A0A8V1AJR0-1|F1NDA6_CHICK Computationally mapped isoform of Solute carrier family 2, facilitated glucose transporter member 8 OS=Gallus gallus OX=9031 GN=SLC2A8 PE=3 SV=1 CANONICAL=F1NDA6-1" }, "locus": { "chromosome": "17", "start_pos": 11000534, "end_pos": 10991774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069531.1", "url": "https://www.ensembl.org/id/ENSGALT00010069531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042795.1", "url": "https://www.ensembl.org/id/ENSGALP00010042795.1" } ] } }, { "isoform_ac": "F1NDA6-1", "url": "https://www.uniprot.org/uniprotkb/F1NDA6/entry#F1NDA6-1", "sequence": { "sequence": "MAAEESQYLLAHRTSDAYLRVQNKKLYLATFAAVLGPLSFGFVLGYSSPAIPELRKIDNPKLRLDSNQASWFGSIVTLGAAAGGILGGYLVDKIGRKLSLMLCSIPFVSGYIVIISAQNVWMLYFGRILTGLASGITSLVVPVYISEISHTDVRGMLGSFVQLMVVTGILGAYIAGLTLKWHWLAVLCSFPPCVMLLFMLFMPETPRFLLDQKKRAEAIAALQFLRGPYVDHEWECRQIEANVEEEGLSLFEFKNPSIYRPLLIGVILMFLQQVTGINAVMFYAETIFEDANFQDSRMASVVVGFIQVCFTAVAALIIDKTGRKVLLYVSGMIMALSTALFGFYFKMVLPNGNNSSNTDLWFTLNSVTPGTDTRLSWLAVVSLGLFVAGFALGWGPVPWLVMSEIFPLKARGVSSSACVLTNWVMAFLVTKEFHDFIGFLTSYGTFWLFSAFCCLSVTFAAFYVPETKGRTLEQIEAYFRKS", "length": 482, "header": "tr|F1NDA6-1|F1NDA6_CHICK Isoform 1 of Solute carrier family 2, facilitated glucose transporter member 8 OS=Gallus gallus OX=9031 GN=SLC2A8 PE=3 SV=1 CANONICAL=F1NDA6-1" }, "locus": { "chromosome": "17", "start_pos": 11000534, "end_pos": 10991774, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069528.1", "url": "https://www.ensembl.org/id/ENSGALT00010069528.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042793.1", "url": "https://www.ensembl.org/id/ENSGALP00010042793.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Broiler chickens (Ross strain) lack insulin-responsive glucose transporter GLUT4 and have GLUT8 cDNA.", "journal": "General and comparative endocrinology", "date": "2003-08", "authors": "Seki Yoshinori, Sato Kan, Kono Tatsuyoshi, Abe Hiroyuki, Akiba Yukio", "evidence": [ { "database": "RefSeq", "id": "NP_989706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ], "reference": [ { "type": "PubMed", "id": "12899849", "url": "https://glygen.org/publication/PubMed/12899849" } ] }, { "title": "Characterisation of glucose transporter (GLUT) gene expression in broiler chickens.", "journal": "British poultry science", "date": "2005-08", "authors": "Kono T, Nishida M, Nishiki Y, Seki Y, Sato K, Akiba Y", "evidence": [ { "database": "RefSeq", "id": "NP_989706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989706" } ], "reference": [ { "type": "PubMed", "id": "16268111", "url": "https://glygen.org/publication/PubMed/16268111" } ] } ], "pathway": [ { "id": "gga:378802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:378802", "resource": "KEGG Pathway" }, { "id": "R-GGA-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189200", "resource": "Reactome", "description": "Cellular hexose transport" }, { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480HHY7-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTPEFPEDSQPLLRPLGESAPRSRRVFLAAFAAALGPLSFGFVLGYSSPAIPSLRRAAPPAPRLDNDATSWFGAIVTLGAAVGGVLGGWLVDRAGRKLSLLLCTVPFVAGFAIITAAQNVWMLLGGRLLTGLACGVASLVAPVYISEIAYPEVRGLLGSCVQLMVVTGILLAYLAGWVLEWRWLAVLGSVPPTFMLLLMGCMPETPRFLLTQHKHQEAMAAMQFLWGSEQRWEEPPVGAEHQGFRLAQLRRPGVYKPFVIGVSLMIFQQLSGINAVMFYAETIFEEAKFKESSLASVIVGVIQVLFTAVAALVMDRAGRRVLLTLSGVVMVFSTSAFGTYFKLTQDGPSNSSHVHLLAPVSVEPTDASVGLAWLAVGSVCLFIAGFALGWGPIPWLLMSEIFPLHVKGVATGVCVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLACVPETKGKTLEQITAHFEGR", "length": 478 }, "evidence": [ { "id": "F1NDA6", "url": "https://omabrowser.org/oma/group/F1NDA6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MZY9-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTPEDQEETQPLLRPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLRRAAPPAPHLDEDAASWFGAIVTLGAAAGGVLGGWLLDRAGRKLSLVLCALPFVAGFAVITAAQNLWMLLGGRLLTGLACGIASLVAPVYISEIAYPEVRGLLGSCVQLMVVTGILLAYLAGWVLEWRWLAVLGCVAPSFMLLLMCFMPETPRFLLSQHKHQEAMAAMQFLWGYAQGWEEPPLGAQHQDFHVAQLRRPGVYKPFIIGISLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTATAALIMDRAGRRLLLTLSGVVMVFSTSAFGAYFKLTEGGPSNSSHVDLPALISMEAADTNVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGVCVLTNWFMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFGVLFTLACVPETKGKTLEQITAHFEGR", "length": 478 }, "evidence": [ { "id": "F1NDA6", "url": "https://omabrowser.org/oma/group/F1NDA6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54UC8-1", "protein_name": "Sugar transporter family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVVNKKTSKEVNIYDNVVFEDIGEFASKKKKQDRFKHINARNPLVKTWKPLWLIRLGSSTGLIITLSASGGLIFGYNTGIIGPALGHINNEYHLNTILQGLIVCSTLLGALIGSVSGGFLADWIGRKTVVLLTAIVTIGGAISSSATNPLSLVASLRIILGLGVGMSSGVCPLMVAEVVPVEKRGVYGSVFQLFITLGLLWSNVMGLLLIESGIHNWRWMFAIGSLPGFFMLLCWTVLNESPVWVENQRLKKERKLQESAISNSKPKKSSFRILMEKKNRRPLFIGVILATFQQLTGINAFMYFSNLIFFKAGFTGEYGAITCSCILQLWNVSFTIIAACTVDRLGRRPLLFIGSIVMTCADLLIALFYVALTGKVQGWLSIICLFIFVAAFAMSIGTLFWFIVNEIFDPEAKDIGAPILIGLQWLFNMLLSLTFVGAVPYIGDSTMFWIFGGIGITCVVLLAIFLPPEKIQQSELESDVLPDSFKQAATVYNDEVELSPSEKKNNFYIPNEDAEEILENLSELPSENMEIPRNIEN", "length": 537 }, "evidence": [ { "id": "F1NDA6", "url": "https://omabrowser.org/oma/group/F1NDA6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FRL3-1", "protein_name": "Sugar transporter ERD6-like 6", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSFRDDNEEARNDLRRPFIHTGSWYRMGSRQSSMMGSSQVIRDSSISVLACVLIVALGPIQFGFTCGYSSPTQAAITKDLGLTVSEYSVFGSLSNVGAMVGAIASGQIAEYIGRKGSLMIAAIPNIIGWLCISFAKDTSFLYMGRLLEGFGVGIISYTVPVYIAEIAPQNMRGGLGSVNQLSVTIGIMLAYLLGLFVPWRILAVLGILPCTLLIPGLFFIPESPRWLAKMGMTDEFETSLQVLRGFETDITVEVNEIKRSVASSTKRNTVRFVDLKRRRYYFPLMVGIGLLVLQQLGGINGVLFYSSTIFESAGVTSSNAATFGVGAIQVVATAISTWLVDKAGRRLLLTISSVGMTISLVIVAAAFYLKEFVSPDSDMYSWLSILSVVGVVAMVVFFSLGMGPIPWLIMSEILPVNIKGLAGSIATLANWFFSWLITMTANLLLAWSSGGTFTLYGLVCAFTVVFVTLWVPETKGKTLEELQSLFR", "length": 487 }, "evidence": [ { "id": "F1NDA6", "url": "https://omabrowser.org/oma/group/F1NDA6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JJZ1-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "Slc2a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPEDPQETQPLLRSPGARAPGGRRVFLATFAAALGPLSFGFALGYSSPAIPSLRRTAPPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWGSEEGWEEPPVGAEHQGFQLAMLRRPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSSLASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQSGPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR", "length": 478 }, "evidence": [ { "id": "F1NDA6", "url": "https://omabrowser.org/oma/group/F1NDA6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR", "length": 477 }, "evidence": [ { "id": "F1NDA6", "url": "https://omabrowser.org/oma/group/F1NDA6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ], "pmid": "" }, { "name": "dehydroascorbic acid transmembrane transporter activity", "id": "GO:0033300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033300", "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ], "pmid": "" }, { "name": "D-glucose transmembrane transporter activity", "id": "GO:0055056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055056", "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "D-glucose transmembrane transport", "id": "GO:1904659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904659", "evidence": [ { "database": "UniProtKB", "id": "F1NDA6", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17629", "name": "", "equation": "alpha,alpha-trehalose(in) = alpha,alpha-trehalose(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "17629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17629" } ] }, { "id": "60372", "name": "", "equation": "D-fructose(out) = D-fructose(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60372", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60372" } ] }, { "id": "60376", "name": "", "equation": "D-glucose(out) = D-glucose(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60376", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60376" } ] }, { "id": "60380", "name": "", "equation": "L-dehydroascorbate(out) = L-dehydroascorbate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "60380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60380" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-F1NDA6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 482, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-F1NDA6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/F1NDA6" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1NDA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NDA6" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 468, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 353, "end_pos": 355 }, { "start_pos": 354, "end_pos": 356 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1C2E9-1", "uniprot_ac": "E1C2E9", "uniprot_id": "E1C2E9_CHICK", "mass": { "chemical_mass": 22087.0, "monoisotopic_mass": 22087.0 }, "refseq": { "ac": "XP_003642463", "name": "28S ribosomal protein S23, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642463" }, "gene_names": [ { "name": "MRPS23", "type": "recommended", "evidence": [ { "id": "E1C2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" } ] }, { "name": "MRPS23", "type": "synonym", "evidence": [ { "id": "XP_003642463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642463" } ] } ], "protein_names": [ { "name": "Small ribosomal subunit protein mS23", "type": "recommended", "evidence": [ { "id": "E1C2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2E9/entry#names_and_taxonomy" } ] }, { "name": "28S ribosomal protein S23, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003642463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642463" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642463" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C2E9", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPS23", "url": "https://www.uniprot.org/uniprotkb/E1C2E9", "locus": { "chromosome": "19", "start_pos": 9240185, "end_pos": 9238078, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029514", "url": "https://www.ensembl.org/id/ENSGALG00010029514" } ] } } ], "crossref": [ { "id": "E1C2E9", "url": "https://alphafold.ebi.ac.uk/entry/E1C2E9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005559", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005559", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23701", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23701", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417666", "url": "https://www.ncbi.nlm.nih.gov/gene/417666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417666", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417666", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEDKPIW", "url": "https://omabrowser.org/oma/group/TEDKPIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1AP03", "url": "https://www.orthodb.org/?gene=A0A8V1AP03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C2E9", "url": "https://www.orthodb.org/?gene=E1C2E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15925", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15925", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15925:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15925:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642463", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V1AP03", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1AP03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2E9", "url": "https://www.uniprot.org/uniprotkb/E1C2E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2E9-1", "url": "https://www.uniprot.org/uniprotkb/E1C2E9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGSRMQKTGSVFSRTRNLLRIGVIQKPLWFDVYATFPPLREPLYRVPRPRYGKVTDDVPPIFYREDEVRAKFYRIYGSGPKPFDLSQPNYKSTCQRFVEKYNELKEEGKIEEENLFEETGKALLASGIILQRRGTDKVAQQDHQDAEARDSVLRLQLQTVLEELQEKKESQEEQMPELRETQKENPSS", "length": 189, "header": "tr|E1C2E9-1|E1C2E9_CHICK Isoform 1 of Small ribosomal subunit protein mS23 OS=Gallus gallus OX=9031 GN=MRPS23 PE=1 SV=3 CANONICAL=E1C2E9-1" }, "isoforms": [ { "isoform_ac": "A0A8V1AP03-1", "url": "https://www.uniprot.org/uniprotkb/E1C2E9/entry#A0A8V1AP03-1", "sequence": { "sequence": "MAGSRMQKTGSVFSRTRNLLRIGVIQKPLWFDVYATFPPLREPLYRVPRPRYGKVTDDVPPIFYREDEVRAKFYRIYGSGPKPFDLSQPNYKSTCQSTTGSSGCGSQGFCTTSATSNRVGRVAGEEGKSGGADARTERNTEGKSFILTAVLLSWHILQLGIVCPWYSSAQEPACPSAQPGGSKK", "length": 184, "header": "tr|A0A8V1AP03-1|E1C2E9_CHICK Computationally mapped isoform of Small ribosomal subunit protein mS23 OS=Gallus gallus OX=9031 GN=MRPS23 PE=1 SV=1 CANONICAL=E1C2E9-1" }, "locus": { "chromosome": "19", "start_pos": 9239992, "end_pos": 9238209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071339.1", "url": "https://www.ensembl.org/id/ENSGALT00010071339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044030.1", "url": "https://www.ensembl.org/id/ENSGALP00010044030.1" } ] } }, { "isoform_ac": "E1C2E9-1", "url": "https://www.uniprot.org/uniprotkb/E1C2E9/entry#E1C2E9-1", "sequence": { "sequence": "MAGSRMQKTGSVFSRTRNLLRIGVIQKPLWFDVYATFPPLREPLYRVPRPRYGKVTDDVPPIFYREDEVRAKFYRIYGSGPKPFDLSQPNYKSTCQRFVEKYNELKEEGKIEEENLFEETGKALLASGIILQRRGTDKVAQQDHQDAEARDSVLRLQLQTVLEELQEKKESQEEQMPELRETQKENPSS", "length": 189, "header": "tr|E1C2E9-1|E1C2E9_CHICK Isoform 1 of Small ribosomal subunit protein mS23 OS=Gallus gallus OX=9031 GN=MRPS23 PE=1 SV=3 CANONICAL=E1C2E9-1" }, "locus": { "chromosome": "19", "start_pos": 9239879, "end_pos": 9238209, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071340.1", "url": "https://www.ensembl.org/id/ENSGALT00010071340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044031.1", "url": "https://www.ensembl.org/id/ENSGALP00010044031.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417666", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417666", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIN7-1", "protein_name": "Small ribosomal subunit protein mS23", "gene_name": "Mrps23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGSRLETVGSVFSRTRDLMRAGVLKEKPLWYDIYKAFPPLKEPVFRRPRLRYGKAKADIQDIFYREDQIRAKFFSTYGSGHKAIDLFNPNFKSTCQRFVEKYTELQSLGETDEEKLFVETGKALLAEGVILRRVREAKTVNVRLQSSSEGNDPLEEDGQKQRVQVKQEPETASSPP", "length": 177 }, "evidence": [ { "id": "E1C2E9", "url": "https://omabrowser.org/oma/group/E1C2E9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QDB6-1", "protein_name": "Small ribosomal subunit protein mS23", "gene_name": "mrps23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGSRLEKFGTVFTRVRDLLRAGVLKPEEKPIWYDVYAAFPPKKEPLYQKPRRPRVPAADPVPQLFYKEDEIRAKFFEVYGNGPKAFEPLMPNFISSCQKFVMKYSELESRGDIKPELLFEETAKALLSEGIYLRKRGGPVQVAPESRDPLLSMKLTDMLAEQQKDKETNIPEKQPEAETLNPDSQTS", "length": 188 }, "evidence": [ { "id": "E1C2E9", "url": "https://omabrowser.org/oma/group/E1C2E9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IP62-1", "protein_name": "Small ribosomal subunit protein mS23", "gene_name": "mRpS23", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQSRLEKIGTIFTRVQGLLRGGAMKTEDKPIWYDVYAAFPPKLEPRFDRPAPEIPVRQIFYAEDVVRAKLHKENKPQETISLFDHRRSTQSQQFVQIYQDLKGQGALDEQRIYETALDLLAEQRQQARLETTPEECLPEQDSESKSQLLSDFKEAVVSQQITSSPAPPAPKGKKEANVGINIDSLFKD", "length": 189 }, "evidence": [ { "id": "E1C2E9", "url": "https://omabrowser.org/oma/group/E1C2E9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VE22-1", "protein_name": "Small ribosomal subunit protein mS23", "gene_name": "Mrps23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSRLETVGSVFSRTRDLMRAGVLKEKPLWYDIYKAFPPLREPVFRRPRLRYGKAKADIQDIFYQEDQIRAKFFATYGSGQKAFDLFNPNFKSTCQRFVEKYTELQNLGETDEEKLFVETGKALLAEGIILRRVREARTVSVRLQASSEGHEPQEDDDLAQRGQVKQEPETAPSPP", "length": 177 }, "evidence": [ { "id": "E1C2E9", "url": "https://omabrowser.org/oma/group/E1C2E9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3D9-1", "protein_name": "Small ribosomal subunit protein mS23", "gene_name": "MRPS23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGSRLETVGSIFSRTRDLVRAGVLKEKPLWFDVYDAFPPLREPVFQRPRVRYGKAKAPIQDIWYHEDRIRAKFYSVYGSGQRAFDLFNPNFKSTCQRFVEKYTELQKLGETDEEKLFVETGKALLAEGVILRRVGEARTQHGGSHVSRKSEHLSVRPQTALEENETQKEVPQDQHLEAPADQSKGLLPP", "length": 190 }, "evidence": [ { "id": "E1C2E9", "url": "https://omabrowser.org/oma/group/E1C2E9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E1C2E9", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "E1C2E9", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "E1C2E9", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "E1C2E9", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "E1C2E9", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C2E9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 189, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C2E9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C2E9" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2E9" }, { "id": "PF10484", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10484" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small ribosomal subunit protein mS23 conserved", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 127, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1BZV4-1", "uniprot_ac": "E1BZV4", "uniprot_id": "E1BZV4_CHICK", "mass": { "chemical_mass": 18308.0, "monoisotopic_mass": 18308.0 }, "refseq": { "ac": "NP_001264456", "name": "regenerating islet-derived protein 4 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456" }, "gene_names": [ { "name": "REG4A", "type": "recommended", "evidence": [ { "id": "E1BZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZV4" } ] }, { "name": "REG4A", "type": "synonym", "evidence": [ { "id": "NP_001264456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456" } ] }, { "name": "REG4", "type": "synonym", "evidence": [ { "id": "NP_001264456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456" } ] } ], "protein_names": [ { "name": "Rerating family member 4A", "type": "synonym", "evidence": [ { "id": "E1BZV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZV4/entry#names_and_taxonomy" } ] }, { "name": "regenerating family member 4", "type": "synonym", "evidence": [ { "id": "NP_001264456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456" } ] }, { "name": "regenerating islet-derived family, member 4", "type": "synonym", "evidence": [ { "id": "NP_001264456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456" } ] }, { "name": "regenerating islet-derived protein 4 precursor", "type": "synonym", "evidence": [ { "id": "NP_001264456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX272108.4, BX272163.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992428 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Apr 11, 2013 this sequence version replaced XP_422224.2. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1BZV4", "url": "https://www.uniprot.org/uniprotkb/E1BZV4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "REG4A", "url": "https://www.uniprot.org/uniprotkb/E1BZV4", "locus": { "chromosome": "8", "start_pos": 4247185, "end_pos": 4245757, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013342", "url": "https://www.ensembl.org/id/ENSGALG00010013342" } ] } } ], "crossref": [ { "id": "E1BZV4", "url": "https://alphafold.ebi.ac.uk/entry/E1BZV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002931", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002931", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03594", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03594", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424379", "url": "https://www.ncbi.nlm.nih.gov/gene/424379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424379", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWQWTSG", "url": "https://omabrowser.org/oma/group/AWQWTSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1BZV4", "url": "https://www.orthodb.org/?gene=E1BZV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45710:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1BZV4", "url": "https://www.uniprot.org/uniprotkb/E1BZV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZV4-1", "url": "https://www.uniprot.org/uniprotkb/E1BZV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMAARCALLLLCCMVLLPVVGARYLLSCPKGWSYYKQSCFRYFRQHRTWEEAEAQCQNSYSGAHLAWVEEPKEAATLSRVIMYYQRTQPVWLGLHYLRQSRDWRWTHGVKFDDLRTLPGNGAQGGSCALLTRSSSFTVWSSADCDRQHHFICKFTPSQ", "length": 158, "header": "tr|E1BZV4-1|E1BZV4_CHICK Isoform 1 of Rerating family member 4A OS=Gallus gallus OX=9031 GN=REG4A PE=4 SV=3 CANONICAL=E1BZV4-1" }, "isoforms": [ { "isoform_ac": "E1BZV4-1", "url": "https://www.uniprot.org/uniprotkb/E1BZV4/entry#E1BZV4-1", "sequence": { "sequence": "MMAARCALLLLCCMVLLPVVGARYLLSCPKGWSYYKQSCFRYFRQHRTWEEAEAQCQNSYSGAHLAWVEEPKEAATLSRVIMYYQRTQPVWLGLHYLRQSRDWRWTHGVKFDDLRTLPGNGAQGGSCALLTRSSSFTVWSSADCDRQHHFICKFTPSQ", "length": 158, "header": "tr|E1BZV4-1|E1BZV4_CHICK Isoform 1 of Rerating family member 4A OS=Gallus gallus OX=9031 GN=REG4A PE=4 SV=3 CANONICAL=E1BZV4-1" }, "locus": { "chromosome": "8", "start_pos": 4247089, "end_pos": 4246270, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010032111.1", "url": "https://www.ensembl.org/id/ENSGALT00010032111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018901.1", "url": "https://www.ensembl.org/id/ENSGALP00010018901.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424379", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QBM5-1", "protein_name": "Regenerating islet-derived protein 4", "gene_name": "Reg4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAPKCVRLLLLLSCVAGPEVLSDLVRPSCASGWFYYKSHCYGYFRKMENWSHAELECQSYGNGSHLASVLNEKEASVISNYIFGYQRNLPVWIGLHDPQKNQLWRWIDGSTQLYRPWNRRTKSEGRHCAALNPKDRFLTWNKNRCNEHQHFLCKYKP", "length": 157 }, "evidence": [ { "id": "E1BZV4", "url": "https://omabrowser.org/oma/group/E1BZV4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1BZV4", "url": "https://www.uniprot.org/uniprotkb/E1BZV4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1BZV4", "url": "https://www.uniprot.org/uniprotkb/E1BZV4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "E1BZV4", "url": "https://www.uniprot.org/uniprotkb/E1BZV4" } ], "pmid": "" }, { "name": "mannan binding", "id": "GO:2001065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001065", "evidence": [ { "database": "UniProtKB", "id": "E1BZV4", "url": "https://www.uniprot.org/uniprotkb/E1BZV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1BZV4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 158, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1BZV4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1BZV4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C020-1", "uniprot_ac": "E1C020", "uniprot_id": "E1C020_CHICK", "mass": { "chemical_mass": 73812.0, "monoisotopic_mass": 73812.0 }, "refseq": { "ac": "XP_004949767", "name": "zinc finger and BTB domain-containing protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949767" }, "gene_names": [ { "name": "ZBTB5", "type": "recommended", "evidence": [ { "id": "E1C020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ] }, { "name": "ZBTB5", "type": "synonym", "evidence": [ { "id": "XP_004949767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949767" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 5", "type": "recommended", "evidence": [ { "id": "E1C020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C020/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004949767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949767" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949767" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB5", "url": "https://www.uniprot.org/uniprotkb/E1C020", "locus": { "chromosome": "Z", "start_pos": 85674626, "end_pos": 85648081, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001178", "url": "https://www.ensembl.org/id/ENSGALG00010001178" } ] } } ], "crossref": [ { "id": "ENSGALG00000005354", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005354", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18196", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18196", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "431260", "url": "https://www.ncbi.nlm.nih.gov/gene/431260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431260", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CRIDNDT", "url": "https://omabrowser.org/oma/group/CRIDNDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C020", "url": "https://www.orthodb.org/?gene=E1C020", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949767", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C020-1", "url": "https://www.uniprot.org/uniprotkb/E1C020-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFTVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDILLAASHLHLNSVVKACKHYLTTRTLPMSPPSDRVQEQNARIQRSFMLQQLGLSIVSSALNSTQSSEEQPSTMSSTMRSNIEQRSAFPIRRLHKRKQSSEDRARQRMRPAIDEAVSDVAPESGQSVHSREDFFSPDSLKIVDNSKADAVTDNQEDNNILFDQSFSAQEDTQVPSQSDNSGGNISQMSMASQATQVETSFDQEAASEKNNFPCDNPEVSINEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGGVVSAEKIELSPESSDRSFSDPQSTTDRVGDIHIMEVSNNLEHKSTFSISNFLNKGRGGSYGASQTTDDNIPNTTSDCRMDSDASFLMSPESGPAGGHSSATVSHVENPFSEPAESHFVRPMQDVMGLPCVQTSGYRAAEQFGMDFPRSGLGLHSLSRAMIGSVRGGASSFPGYRRIAPKMPVVTSVRSSQLQDNSPSSQLIINGTTSFENGHPSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "length": 673, "header": "tr|E1C020-1|E1C020_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 5 OS=Gallus gallus OX=9031 GN=ZBTB5 PE=4 SV=1 CANONICAL=E1C020-1" }, "isoforms": [ { "isoform_ac": "E1C020-1", "url": "https://www.uniprot.org/uniprotkb/E1C020/entry#E1C020-1", "sequence": { "sequence": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFTVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDILLAASHLHLNSVVKACKHYLTTRTLPMSPPSDRVQEQNARIQRSFMLQQLGLSIVSSALNSTQSSEEQPSTMSSTMRSNIEQRSAFPIRRLHKRKQSSEDRARQRMRPAIDEAVSDVAPESGQSVHSREDFFSPDSLKIVDNSKADAVTDNQEDNNILFDQSFSAQEDTQVPSQSDNSGGNISQMSMASQATQVETSFDQEAASEKNNFPCDNPEVSINEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGGVVSAEKIELSPESSDRSFSDPQSTTDRVGDIHIMEVSNNLEHKSTFSISNFLNKGRGGSYGASQTTDDNIPNTTSDCRMDSDASFLMSPESGPAGGHSSATVSHVENPFSEPAESHFVRPMQDVMGLPCVQTSGYRAAEQFGMDFPRSGLGLHSLSRAMIGSVRGGASSFPGYRRIAPKMPVVTSVRSSQLQDNSPSSQLIINGTTSFENGHPSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "length": 673, "header": "tr|E1C020-1|E1C020_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 5 OS=Gallus gallus OX=9031 GN=ZBTB5 PE=4 SV=1 CANONICAL=E1C020-1" }, "locus": { "chromosome": "Z", "start_pos": 85671170, "end_pos": 85670937, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002718.1", "url": "https://www.ensembl.org/id/ENSGALT00010002718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001268.1", "url": "https://www.ensembl.org/id/ENSGALP00010001268.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431260", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BH97-1", "protein_name": "Zinc finger and BTB domain-containing protein 5", "gene_name": "ZBTB5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIMVGNRHFKAHRSILAACSMHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLPMSPPSERVQQQSARMQRSFMLQQLGLSIVSSVLNSSQSGEEQPAPMSSSMLSNLDQQTPFPMRRLHKRKQSAEERARQRLPPALDESAISDVTPENGPSGVHSREEFFSPDSLKIVDNPKATGMADNQDDSAMMFEQSFGAQEEAQVPSQSDNSAGNMAQLSMASRATQVKTSFEQEAATEKSGFQCENPEVGLGEKEHMRVVVKSESLSSPEPQDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEVTNNLEHKSTFSISNFLNKSRGSNFSANQSNDDNIPNTTSDCRLEGEAPYLLSPEAGPAGGPSSAPGPHGENPFSEPADSHFVRPMQEVMGLPCVQTSSYQGGGQFGMDFSRSGMGLHSSFSRVMMGSPRGGASNFPYYRRIAPKMPVVTSVRSSQIPENVASSQLMMNTATSSFENGHPSQPGPPQLTRASADVLLKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "length": 677 }, "evidence": [ { "id": "E1C020", "url": "https://omabrowser.org/oma/group/E1C020/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZFS3-1", "protein_name": "Zinc finger and BTB domain-containing protein 5", "gene_name": "Zbtb5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLPMSPPSERVQEQSARMQRSFMLQQLGLSIVSSALSSSQSGEEPSAPMSSSMRNNLDQRTPFPMRRLHKRKQTVEERARQRLRSSMDESAISDVTPESGPSGVHSREEFFSPDSLKIVDNPKPDGMADNQEDSAMMFDRPFGAQEDAQMPSQSDGSAGNMASRATQVETSFEQEAVAEKGSFQCENPEVGLGEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEVTNNLEHKTSFSISNFLNKSRGSNFSTSQSTDDNLPNTTSDCRLEGEAPYLLSPEAGPAGGPSSAPGSHVENPFSEPADSHFVRPVQEVMGLPCVQTSGYQGEQFGMDFPRSGLGLHSSFSRAMMGSPRGGASNFPYYRRIAPKMPVVTSVRSSQISENQASSQLMMNGASSFENGHSSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "length": 670 }, "evidence": [ { "id": "E1C020", "url": "https://omabrowser.org/oma/group/E1C020/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15062-1", "protein_name": "Zinc finger and BTB domain-containing protein 5", "gene_name": "ZBTB5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLPMSPPSERVQEQSARMQRSFMLQQLGLSIVSSALNSSQNGEEQPAPMSSSMRSNLDQRTPFPMRRLHKRKQSAEERARQRLRPSIDESAISDVTPENGPSGVHSREEFFSPDSLKIVDNPKADGMTDNQEDSAIMFDQSFGTQEDAQVPSQSDNSAGNMAQLSMASRATQVETSFDQEAAPEKSSFQCENPEVGLGEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEVTNNLEHKSTFSISNFLNKSRGNNFTANQNNDDNIPNTTSDCRLESEAPYLLSPEAGPAGGPSSAPGSHVENPFSEPADSHFVRPMQEVMGLPCVQTSGYQGGEQFGMDFSRSGLGLHSSFSRVMIGSPRGGASNFPYYRRIAPKMPVVTSVRSSQIPENSTSSQLMMNGATSSFENGHPSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "length": 677 }, "evidence": [ { "id": "E1C020", "url": "https://omabrowser.org/oma/group/E1C020/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TQG0-1", "protein_name": "Zinc finger and BTB domain-containing protein 5", "gene_name": "Zbtb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLPMSPSSERAQEQSARMQRSFMLQQLGLSIVSSALSSSQSAEEPTAPMSSSMRSSLDQRTPFPMRRLHKRKQSVEERARQRLRSSMEESAISDVTPESGPAGVHSREEFFSPDSLKIVDNPKPDGMADNQEDGAMMFDRPFGAQEDAQVPSQSDGSAGNMASRATQVETSFEQEAVAEKGSFQCENPEVGLGEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEVTNNLEHKTSFSISNFLNKSRGSNFSASQSTDDNLPNTTSDCRLEGEAPYLLSPEAGPAGGPSSAPGSHVENPFSEPADSHFVRPMQEVMGLPCVQTSGYQGEQFGMDFSRSGLGLHSSFSRAMMGSPRGGASNFPYYRRIAPKMPVVTSVRSSQISENSASSQLMMNGATSFENGHTSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "length": 670 }, "evidence": [ { "id": "E1C020", "url": "https://omabrowser.org/oma/group/E1C020/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "E1C020", "url": "https://www.uniprot.org/uniprotkb/E1C020" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C020" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 93, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1C020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C020" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 609, "end_pos": 636, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 562, "end_pos": 564 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C027-1", "uniprot_ac": "E1C027", "uniprot_id": "E1C027_CHICK", "mass": { "chemical_mass": 98754.0, "monoisotopic_mass": 98754.0 }, "refseq": { "ac": "XP_003641286", "name": "NF-X1-type zinc finger protein NFXL1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641286" }, "gene_names": [ { "name": "NFXL1", "type": "recommended", "evidence": [ { "id": "E1C027", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C027" } ] }, { "name": "NFXL1", "type": "synonym", "evidence": [ { "id": "XP_003641286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641286" } ] } ], "protein_names": [ { "name": "NF-X1-type zinc finger protein NFXL1", "type": "synonym", "evidence": [ { "id": "XP_003641286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641286" } ] }, { "name": "Nuclear transcription factor, X-box binding like 1", "type": "synonym", "evidence": [ { "id": "E1C027", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C027/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641286" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C027", "url": "https://www.uniprot.org/uniprotkb/E1C027" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NFXL1", "url": "https://www.uniprot.org/uniprotkb/E1C027", "locus": { "chromosome": "4", "start_pos": 66149800, "end_pos": 66108392, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010013901", "url": "https://www.ensembl.org/id/ENSGALG00010013901" } ] } } ], "crossref": [ { "id": "E1C027", "url": "https://alphafold.ebi.ac.uk/entry/E1C027", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014138", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014138", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06008", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06008", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16697", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16697", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859761", "url": "https://www.ncbi.nlm.nih.gov/gene/100859761", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859761", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859761", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCQSVCH", "url": "https://omabrowser.org/oma/group/KCQSVCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C027", "url": "https://www.orthodb.org/?gene=E1C027", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12360:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12360:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641286", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C027", "url": "https://www.uniprot.org/uniprotkb/E1C027", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C027-1", "url": "https://www.uniprot.org/uniprotkb/E1C027-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAWRQGGRGRGRARLGDGLSNRAGAAARPPAPVGRGGACVQMAASGGEGTCELSSQKKFDEIKKANQAAARKLAEEQFSSSSEDDDEDAEIKQGKILAKTFTIYTSQTDGDASELERTRQYMNEAFQSGAMTCLICIASVKRNQAVWSCCGCFCIFHLVCIQKWAKDSLFLVSSPLTDDDFGKKDYPWPCPKCRFEYKRSETPNKYYCYCGKVENPTVDPWLVPHSCGQVCEKEFKPPCGHKCLLLCHPGPCPPCPKMVTTSCHCRKAKPVPRRCSAKEWSCRLPCGRMLLCGQHTCENPCHSGDCQPCPRVSKQRCICGRQTAERLCASPQWQCEQVCGKALPCGNHTCEQVCHAGPCGDCPRSGKRSCPCGKSKFTLPCTEDVPTCGDSCDKVLECGIHKCLQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKPYLCETKCTKIRDCQKHQCRRKCCPGNCPPCDQVCGRTLGCRNHKCPSGCHRGSCNPCPETVDVKCNCGKTVIKVPCGRERTIKPPKCKQLCSRPPTCHHPTQEKHYCHFGRCPPCRQTCQKTLTCGHLCPVSCHDEALVKQAGIHQFAGPWEQPSEPAFIQTALPCPPCEVPIPVECLGQHEVSPLPCHSAGPYSCKRFCGRLLSCQNHTCMKECHHVTKINSNADGKKAGPECLRCEEECTKPRPLGCPHRCVLPCHPGDCPSCLQMLKIKCHCKLSVLYIECLKLTSADIKEKDLLTSCKNQCPKQLPCGHRCKEICHSGDCPLNCSQKVKLKCPCKRLKKEVQCSKIQEGQVSLECDALCKEMKRKASEIKEAEAKAAIEEEKRRQQAELEAFENRLKGRRKNKRRRDEVEIEQSSWQKYKNLIMLPVFGVAVVMVAWLMVYND", "length": 886, "header": "tr|E1C027-1|E1C027_CHICK Isoform 1 of Nuclear transcription factor, X-box binding like 1 OS=Gallus gallus OX=9031 GN=NFXL1 PE=1 SV=3 CANONICAL=E1C027-1" }, "isoforms": [ { "isoform_ac": "E1C027-1", "url": "https://www.uniprot.org/uniprotkb/E1C027/entry#E1C027-1", "sequence": { "sequence": "MEAAWRQGGRGRGRARLGDGLSNRAGAAARPPAPVGRGGACVQMAASGGEGTCELSSQKKFDEIKKANQAAARKLAEEQFSSSSEDDDEDAEIKQGKILAKTFTIYTSQTDGDASELERTRQYMNEAFQSGAMTCLICIASVKRNQAVWSCCGCFCIFHLVCIQKWAKDSLFLVSSPLTDDDFGKKDYPWPCPKCRFEYKRSETPNKYYCYCGKVENPTVDPWLVPHSCGQVCEKEFKPPCGHKCLLLCHPGPCPPCPKMVTTSCHCRKAKPVPRRCSAKEWSCRLPCGRMLLCGQHTCENPCHSGDCQPCPRVSKQRCICGRQTAERLCASPQWQCEQVCGKALPCGNHTCEQVCHAGPCGDCPRSGKRSCPCGKSKFTLPCTEDVPTCGDSCDKVLECGIHKCLQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKPYLCETKCTKIRDCQKHQCRRKCCPGNCPPCDQVCGRTLGCRNHKCPSGCHRGSCNPCPETVDVKCNCGKTVIKVPCGRERTIKPPKCKQLCSRPPTCHHPTQEKHYCHFGRCPPCRQTCQKTLTCGHLCPVSCHDEALVKQAGIHQFAGPWEQPSEPAFIQTALPCPPCEVPIPVECLGQHEVSPLPCHSAGPYSCKRFCGRLLSCQNHTCMKECHHVTKINSNADGKKAGPECLRCEEECTKPRPLGCPHRCVLPCHPGDCPSCLQMLKIKCHCKLSVLYIECLKLTSADIKEKDLLTSCKNQCPKQLPCGHRCKEICHSGDCPLNCSQKVKLKCPCKRLKKEVQCSKIQEGQVSLECDALCKEMKRKASEIKEAEAKAAIEEEKRRQQAELEAFENRLKGRRKNKRRRDEVEIEQSSWQKYKNLIMLPVFGVAVVMVAWLMVYND", "length": 886, "header": "tr|E1C027-1|E1C027_CHICK Isoform 1 of Nuclear transcription factor, X-box binding like 1 OS=Gallus gallus OX=9031 GN=NFXL1 PE=1 SV=3 CANONICAL=E1C027-1" }, "locus": { "chromosome": "4", "start_pos": 66149472, "end_pos": 66108528, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033325.1", "url": "https://www.ensembl.org/id/ENSGALT00010033325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019668.1", "url": "https://www.ensembl.org/id/ENSGALP00010019668.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859761", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859761", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q8I7-1", "protein_name": "Nuclear transcription factor, X-box binding-like 1", "gene_name": "Nfxl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAPWRQVAAGRGRARGRATAVPLSGNGVPFGGAGGGRAKGSGGAVSSGPGPGGAAALAPAGRGQRSAGGEAPQPPGARGEDGSELMSQKKFEEIKKSNQAAARKLLEEHCSSSSEEEGDEDLEGKQGKIVANTFTTYTTHTDGDIHELERTKQYLNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDYPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPSCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCSAKQWSCQLPCGRKLLCGHHKCENPCHAGNCQPCPRVSRQKCVCGKKVAERSCASPVWHCDQVCGKTLPCGNHTCEQVCHVGACGECPRSGKRSCPCQKSKFSLPCTEDVPTCGDSCDKILECGIHRCSQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKPYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNAKVTVPCGRERTTRPPKCKELCSRPPTCHHASQEKHRCHFGPCPPCHQPCQKVLEKCGHLCPESCHDQALVKQTGRHQPSGPWEQPAEPAFIQTALPCPPCQVPIPVECLGKHEVSPLPCHAVGPYSCKRLCGRMLRCQNHTCMKECHKVTEVDSSTGKNKAGPECFHCEEGCSKSRPAGCPHPCVLPCHPGKCPPCVQMLRIKCHCKITSLYVECRKITTADVSEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPFNCNQKVKLRCPCKRIKRELPCNKVRENQVSVECDATCKEMKRKASEVKEAEANAALEEEKRRQQAELEAFENRLKGRRKKSRKRDEVAVELSPWQKYKSYLLPVCAVVVAVLMWYIFHGVD", "length": 918 }, "evidence": [ { "id": "E1C027", "url": "https://omabrowser.org/oma/group/E1C027/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LNF3-1", "protein_name": "Nuclear transcription factor, X-box binding-like 1", "gene_name": "Nfxl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASWRQVAAGRGRARGRGTAVPLSGNGVPLSGAGGGRAKGSGGAVPSAPGPRRAATPGPAGHKQRSAGGEAPQPLWVGGEDGSELISQRKFEEIKKANQAAARKLVEEHCSSSSEEEEGDEDFEGKQGKIVANTFITYTTHTDGDVHELEKTKQYLNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDYPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPSCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCSAKQWSCQLPCGRKLLCGQHSCENPCHAGNCQPCPRVSRQKCVCGKKVAERSCASPVWHCDQVCRKTLPCGNHTCEQVCHVGACGECPRSGKRSCPCQKSKFSLPCTEDVPTCGDSCDKILECGIHRCSQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKTYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNAKVTVPCGRERTTRPPKCKELCSRPPTCHHSSQEKHRCHFGPCPPCHQPCQKVLEKCGHLCPISCHDQALVKQTGRHQLSGPWEQPAEPAFIQTALPCPPCQVPIPVECLGKHEVSPLPCHAVGPYSCKRLCGRMLNCQNHTCTKECHKVTEVDGCPGRHKMKIRYHFIGGICLIWLHVHICVCIHVCKNQRSTSDIFFHHSSHCFEAGPECLQCEEGCSKSRPAGCPHPCVLPCHPGKCPPCVQMLRIKCHCKITNLYVECRKITTADVSEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPYNCNQKVKLRCPCKRIKRELPCNKIRGNQVSVECDAACKEMKRKASEIKEAEANAALEEEKRRQQAELEAFENRLKGRRKKNRKRDEVAVQLSPWQKYKSYLFPVCGVVVAVLVWYICHHAD", "length": 965 }, "evidence": [ { "id": "E1C027", "url": "https://omabrowser.org/oma/group/E1C027/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53971-1", "protein_name": "FKBP12-associated protein 1", "gene_name": "FAP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTEHESLGLEQNQDGGDTYRHHNLSDGCISSVEDANEQPSSYEEESDDDMQYYERAIQEISSGDSYVCMICTVEMDYTCQMFACKRCYRVFDYGCIREWALKSTEKTVDRIWKCPNCYYVSKRVPVKNRPTCWCGKVVNPDPNPLDPNSCGQTCNASTCMHGCSKICHLGPHPECTRMVEIMCHCGKHSKSIFCYQSKVMKKNFNCQEVCGLPLSCSIHTCKKKCHPGLCGPCPEMIISKDSPKKQIKCYCGNHTRANIKCSETKFPKSGKSSKDENGNRWIGVFACADNRVVDYSCRKHSFIESCISPPTINGEKACPFLPSSLKTCPCGRTALEELTKPRKHCDDPIPTCDSRCGKPLKCGKHSCPFTCHDKACMEPCLQIDSVKCACEQSTFSVPCGFQGRPRCNIKCESLMSCRRHRCTDRCCSGRPSAIRRKKNLFRTQDLLDESLVEAKHICLKPCNLTLSCGIHKCQRKCHPGKCPPCLESDSNDLVCPCGNTVVPAPVRCGTKLPTCNHPCIKVVRGESTCGHKPMPHTCHSLDVSCPPCTETVFKPCKCGKKTKVRTVCFQTDVSCGIKCGIPLSYCYHTCQKTCHLPGNCQKVCKQTCGQKRLNCNHECPKPCHGKTECPDLPCATLVKIYCKCGRIKKSVTCGAKSDRVSVTESSVLDCNEECEALKRLKELKEAFGIKEETNNFTSNELDALKKLVSVATTFEELQLPFTEAALSVYSKQERWCSQIEAILNKLMDDKTRSSLHFKPMRPPQRHFIRELAKAYGLYSESQDREPMRSVFIKKEDNGASNKPVLSLAEAYPLYESFKQLQKERKAQEFQARTTAKLINFEVQDTEPKVEVAKKNGFLVQNLVAGNTAEDLRRFFEPHLKHTLVVNPQYLILDDGKTALVYPENYETASVNTERDMELLVGHFDFMAKEAFLADSISLCSTEEELERRLDTPVIQEDSPVMDNNT", "length": 965 }, "evidence": [ { "id": "E1C027", "url": "https://omabrowser.org/oma/group/E1C027/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6ZNB6-1", "protein_name": "NF-X1-type zinc finger protein NFXL1", "gene_name": "NFXL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEASWRQVAGGRGRSRGRATAAPSGNGVHLRGAGGGREKGSVGAVPSGTSPGGVATTAAAGSRHSPAGSQALQTTAASELMSQKKFEEIKKANQAAARKLVEEQFSSSSEEGDEDFEGKQGKILANTFITYTTQTDGDTRELERTKQYVNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDCPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPPCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCSAKEWSCQLPCGQKLLCGQHKCENPCHAGSCQPCPRVSRQKCVCGKKVAERSCASPLWHCDQVCGKTLPCGNHTCEQVCHVGACGECPRSGKRFCPCQKSKFSLPCTEDVPTCGDSCDKVLECGIHRCSQRCHRGPCETCRQEVEKHCRCGKHTKRMPCHKPYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNTKVTVPCGRERTTRPPKCKEQCSRPPTCHHTSQEKHRCHFGSCPPCHQPCQKVLEKCGHLCPAPCHDQALIKQTGRHQPTGPWEQPSEPAFIQTALPCPPCQVPIPMECLGKHEVSPLPCHAVGPYSCKRVCGRILDCQNHTCMKECHKVTKTDGCTGKNKAGPECLHCEEGCSKSRPLGCLHPCILRCHPGECPPCVQMLRIKCHCKITSLYVECRKITTADVNEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPFNCNQKVKLRCPCKRIKKELQCNKVRENQVSIECDTTCKEMKRKASEIKEAEAKAALEEEKRRQQAELEAFENRLKGRRKKNRKRDEVAVELSLWQKHKYYLISVCGVVVVVFAWYITHDVN", "length": 911 }, "evidence": [ { "id": "E1C027", "url": "https://omabrowser.org/oma/group/E1C027/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FFK8-1", "protein_name": "NF-X1-type zinc finger protein NFXL2", "gene_name": "NFXL2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTNMAGTATTEFRWKSPPQPPSQEQPISDSDSDSGSDSENHQHRHNDLSNSIFEAYLDCHSSSSPSSIDLAKIQSFLASSSSGAVSCLICLERIKRTDPTWSCTSSCFAVFHLFCIQSWARQCLDLQAARAVTRPSSNPTEPEAVWNCPKCRSSYQKSKIPRRYLCYCGKEEDPPADNPWILPHSCGEVCERPLSNNCGHCCLLLCHPGPCASCPKLVKAKCFCGGVEDVRRCGHKQFSCGDVCERVLDCNIHNCREICHDGECPPCRERAVYKCSCGKVKEEKDCCERVFRCEASCENMLNCGKHVCERGCHAGECGLCPYQGKRSCPCGKRFYQGLSCDVVAPLCGGTCDKVLGCGYHRCPERCHRGPCLETCRIVVTKSCRCGVTKKQVPCHQELACERKCQRVRDCARHACRRRCCDGECPPCSEICGKKLRCRNHKCQSPCHQGPCAPCPIMVTISCACGETHFEVPCGTETNQKPPRCRKLCHITPLCRHGQNQKPHKCHYGACPPCRLLCDEEYPCGHKCKLRCHGPRPPPNREFILKPTKKMLHIQAESTPGSPCPRCPEPVWRPCVGHHLAAEKRMICSDRTQFACDNLCGNPLPCGNHYCSYFCHALDIRSSSLDKRSESCEKCDLRCQKERTPRCQHPCPRRCHPEDCPPCKTLVKRSCHCGAMVHAFECIYYNTMSEKDQMKARSCRGPCHRKLPNCTHLCPEICHPGQCPLPEKCGKKVVVRCKCLTLKKEWVCQDVQAAHRATGSDPKEVPKNQFGVGLLPCDSNCKSKLQVAESVLTQRNVKEIEEKEEPSGKNASKRRKRRGRGQDIQETTRLQKLAVTTKRILMVVMLVAMLAAVSYYGYKGLLWLSDWMNEVEEQRQKSRRYPRI", "length": 883 }, "evidence": [ { "id": "E1C027", "url": "https://omabrowser.org/oma/group/E1C027/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VZF2-1", "protein_name": "NF-X1-type domain-containing protein", "gene_name": "cg15011", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKFNKAQAKNLAAAQKLVDTYASSSEDEGELDENHILELLYKNYKPSDNAGSSKEAARTSTFLENTLHSGAATCLICIGSIRRVEAIWSCESCYCFFHLKCIQRWANDSMMQMKVKAAEQQNGQGHYNHLGEFVPPKRQKSLHWCCPKCRRDYQPADKPTQYNCFCGKEVNPENQPFLVPHSCGEHCGKLLQPKCGHDCKLLCHPGPCPPCAQQAQVSCLCGKSSPRSVRCIDKQWTCQQTCKELLACGKHKCNQVCHQPGKCPPCTSKSLQPCECQRESKMVNCSDRKWKCQNVCGAPFACGLHICEKVCHAGPCGDGECPLQVRSCPCGKNTQVRPCNETEETCGDTCQKLLSCGQHTCTQRCHRGPCISCPIRTKKKCRCGLHEKELPCSKEFACETKCKQMRDCGKHACNRKCCGDQCPPCEKICGKQLSCNKHKCQSVCHNGPCYPCKLESQINCRCGKTKKSVPCGRERSARIVCLELCRITPKCHHAIKHRCHKGDCPPCGQVCGLPNDTSKCGHICKARCHEAVRVNKPKEARPQAKKYEYKALPHPRCEEGVIVTCIGGHEVATWPCWNSKPTSCQRSCARQLKCGNHKCSLVCHFVPLPQDMSAQTGCANCEEGCTVPRPTGCIHACPKGCHPPPCAPCNFVIKTKCHCGLNQLVYKCNEYYDETGSVQEIIERREKLRSCGNRCLKNYPCGHRCTAICHTGKCPNPELCRKKVRIFCACKRLKQEIACDKHRAGQTFLDCDSNCKAEQIRVQAAEQLQLEQKRRDEEERNRLELEKFEAKFGKRKHKERKTVGSGPAKTKIDWQRRAIYAVSILTVVGAIVVAFYADS", "length": 840 }, "evidence": [ { "id": "E1C027", "url": "https://omabrowser.org/oma/group/E1C027/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C027", "url": "https://www.uniprot.org/uniprotkb/E1C027" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1C027", "url": "https://www.uniprot.org/uniprotkb/E1C027" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "E1C027", "url": "https://www.uniprot.org/uniprotkb/E1C027" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1C027", "url": "https://www.uniprot.org/uniprotkb/E1C027" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E1C027", "url": "https://www.uniprot.org/uniprotkb/E1C027" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 647, "end_pos": 649, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C027-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 886, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C027-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C027" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C027", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C027" }, { "id": "SM00438", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00438" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NF-X1-type", "eco_id": "ECO_0000259", "start_pos": 241, "end_pos": 259, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 349, "end_pos": 351 }, { "start_pos": 647, "end_pos": 649 }, { "start_pos": 766, "end_pos": 768 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C047-1", "uniprot_ac": "E1C047", "uniprot_id": "E1C047_CHICK", "mass": { "chemical_mass": 59305.0, "monoisotopic_mass": 59305.0 }, "refseq": {}, "gene_names": [ { "name": "MFSD14A", "type": "recommended", "evidence": [ { "id": "E1C047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C047" } ] } ], "protein_names": [ { "name": "Solute carrier family 71 member 1", "type": "recommended", "evidence": [ { "id": "E1C047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C047/entry#names_and_taxonomy" } ] }, { "name": "Hippocampus abundant transcript 1 protein", "type": "synonym", "evidence": [ { "id": "E1C047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C047/entry#names_and_taxonomy" } ] }, { "name": "Major facilitator superfamily domain-containing 14A", "type": "synonym", "evidence": [ { "id": "E1C047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C047/entry#names_and_taxonomy" } ] }, { "name": "Putative tetracycline transporter-like protein", "type": "synonym", "evidence": [ { "id": "E1C047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C047/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Probable membrane-bound transporter. May play a role in neuronal nutrient sensing and energy homeostasis. Required for the final stages of spermatogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V1A2D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D0#function" }, { "database": "UniProtKB", "id": "ARBA00094115", "url": "https://www.uniprot.org/uniprotkb/ARBA00094115#function" }, { "database": "UniProtKB", "id": "E1C047", "url": "https://www.uniprot.org/uniprotkb/E1C047#function" }, { "database": "UniProtKB", "id": "A0A8V0ZYJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C047", "url": "https://www.uniprot.org/uniprotkb/E1C047" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFSD14A", "url": "https://www.uniprot.org/uniprotkb/E1C047", "locus": { "chromosome": "8", "start_pos": 11679094, "end_pos": 11699227, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023918", "url": "https://www.ensembl.org/id/ENSGALG00010023918" } ] } } ], "crossref": [ { "id": "E1C047", "url": "https://alphafold.ebi.ac.uk/entry/E1C047", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005329", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005329", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17387", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17387", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYJ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZYJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2D0", "url": "https://www.orthodb.org/?gene=A0A8V1A2D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C047", "url": "https://www.orthodb.org/?gene=E1C047", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23504", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23504", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23504:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23504:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZYJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2D0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C047", "url": "https://www.uniprot.org/uniprotkb/E1C047", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C047-1", "url": "https://www.uniprot.org/uniprotkb/E1C047-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRSRDARQRLRWGGGTRWRRVPERWLRPRGRNGQVCLWGRSALPPLPPREDGKMTQGGKKKKRAVNRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLMVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMGFSSESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELNELPVPESPSGGTVVTQYHLQQNSIIPGPPFLFGACSVLLALLVALFIPEHTNLTVRSSNWKKHCGSHGHPHSPQAPGEAKEPLLQDTNV", "length": 545, "header": "tr|E1C047-1|E1C047_CHICK Isoform 1 of Solute carrier family 71 member 1 OS=Gallus gallus OX=9031 GN=MFSD14A PE=3 SV=4 CANONICAL=E1C047-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZYJ4-1", "url": "https://www.uniprot.org/uniprotkb/E1C047/entry#A0A8V0ZYJ4-1", "sequence": { "sequence": "MTQGGKKKKRAVNRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLMVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMGFSSESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELNELPVPESPSGGTVVTQYHLQQNSIIPGPPFLFGACSVLLALLVALFIPEHTNLTVRSSNWKKHCGSHGHPHSPQAPGEAKEPLLQDTNV", "length": 473, "header": "tr|A0A8V0ZYJ4-1|A0A8V0ZYJ4_CHICK Computationally mapped isoform of Solute carrier family 71 member 1 OS=Gallus gallus OX=9031 GN=MFSD14A PE=3 SV=1 CANONICAL=E1C047-1" }, "locus": { "chromosome": "8", "start_pos": 11698866, "end_pos": 11684910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058270.1", "url": "https://www.ensembl.org/id/ENSGALT00010058270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035397.1", "url": "https://www.ensembl.org/id/ENSGALP00010035397.1" } ] } }, { "isoform_ac": "A0A8V1A2D0-1", "url": "https://www.uniprot.org/uniprotkb/E1C047/entry#A0A8V1A2D0-1", "sequence": { "sequence": "MGSNIFLEEKKVVLQRVFLLSVPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLMVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMGFSSESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELNELPVPESPSGGTNSIIPGPPFLFGACSVLLALLVALFIPEHTNLTVRSSNWKKHCGSHGHPHSPQAPGEAKEPLLQDTNV", "length": 475, "header": "tr|A0A8V1A2D0-1|A0A8V1A2D0_CHICK Computationally mapped isoform of Solute carrier family 71 member 1 OS=Gallus gallus OX=9031 GN=MFSD14A PE=3 SV=1 CANONICAL=E1C047-1" }, "locus": { "chromosome": "8", "start_pos": 11694765, "end_pos": 11684910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058266.1", "url": "https://www.ensembl.org/id/ENSGALT00010058266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035395.1", "url": "https://www.ensembl.org/id/ENSGALP00010035395.1" } ] } }, { "isoform_ac": "E1C047-1", "url": "https://www.uniprot.org/uniprotkb/E1C047/entry#E1C047-1", "sequence": { "sequence": "MGRSRDARQRLRWGGGTRWRRVPERWLRPRGRNGQVCLWGRSALPPLPPREDGKMTQGGKKKKRAVNRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLMVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMGFSSESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELNELPVPESPSGGTVVTQYHLQQNSIIPGPPFLFGACSVLLALLVALFIPEHTNLTVRSSNWKKHCGSHGHPHSPQAPGEAKEPLLQDTNV", "length": 545, "header": "tr|E1C047-1|E1C047_CHICK Isoform 1 of Solute carrier family 71 member 1 OS=Gallus gallus OX=9031 GN=MFSD14A PE=3 SV=4 CANONICAL=E1C047-1" }, "locus": { "chromosome": "8", "start_pos": 11699028, "end_pos": 11684910, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058272.1", "url": "https://www.ensembl.org/id/ENSGALT00010058272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035399.1", "url": "https://www.ensembl.org/id/ENSGALP00010035399.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1C047", "url": "https://www.uniprot.org/uniprotkb/E1C047" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1C047", "url": "https://www.uniprot.org/uniprotkb/E1C047" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "E1C047", "url": "https://www.uniprot.org/uniprotkb/E1C047" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C047-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 545, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C047-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C047" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C047" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 508, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 508, "end_pos": 510 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C055-1", "uniprot_ac": "E1C055", "uniprot_id": "E1C055_CHICK", "mass": { "chemical_mass": 22582.0, "monoisotopic_mass": 22582.0 }, "refseq": { "ac": "XP_423026", "name": "GTP-binding protein Di-Ras2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423026" }, "gene_names": [ { "name": "DIRAS2", "type": "recommended", "evidence": [ { "id": "E1C055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C055" } ] }, { "name": "DIRAS2", "type": "synonym", "evidence": [ { "id": "XP_423026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423026" } ] } ], "protein_names": [ { "name": "DIRAS family GTPase 2", "type": "synonym", "evidence": [ { "id": "E1C055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C055/entry#names_and_taxonomy" } ] }, { "name": "GTP-binding protein Di-Ras2", "type": "synonym", "evidence": [ { "id": "XP_423026", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423026" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423026" } ] }, { "annotation": "Displays low GTPase activity and exists predominantly in the GTP-bound form.", "evidence": [ { "database": "UniProtKB", "id": "E1C055", "url": "https://www.uniprot.org/uniprotkb/E1C055#function" }, { "database": "UniProtKB", "id": "ARBA00055536", "url": "https://www.uniprot.org/uniprotkb/ARBA00055536#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C055", "url": "https://www.uniprot.org/uniprotkb/E1C055" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DIRAS2", "url": "https://www.uniprot.org/uniprotkb/E1C055", "locus": { "chromosome": "Z", "start_pos": 44590009, "end_pos": 44660629, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010009307", "url": "https://www.ensembl.org/id/ENSGALG00010009307" } ] } } ], "crossref": [ { "id": "ENSGALG00000005323", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005323", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04140", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04140", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425241", "url": "https://www.ncbi.nlm.nih.gov/gene/425241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425241", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425241", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKETNGA", "url": "https://omabrowser.org/oma/group/CKETNGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C055", "url": "https://www.orthodb.org/?gene=E1C055", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_423026", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423026", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C055", "url": "https://www.uniprot.org/uniprotkb/E1C055", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C055-1", "url": "https://www.uniprot.org/uniprotkb/E1C055-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRESYIPTIEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICQIKGDVESIPIMLVGNKNDENQNREVESSEGEATAKKWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199, "header": "tr|E1C055-1|E1C055_CHICK Isoform 1 of DIRAS family GTPase 2 OS=Gallus gallus OX=9031 GN=DIRAS2 PE=3 SV=1 CANONICAL=E1C055-1" }, "isoforms": [ { "isoform_ac": "E1C055-1", "url": "https://www.uniprot.org/uniprotkb/E1C055/entry#E1C055-1", "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRESYIPTIEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICQIKGDVESIPIMLVGNKNDENQNREVESSEGEATAKKWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199, "header": "tr|E1C055-1|E1C055_CHICK Isoform 1 of DIRAS family GTPase 2 OS=Gallus gallus OX=9031 GN=DIRAS2 PE=3 SV=1 CANONICAL=E1C055-1" }, "locus": { "chromosome": "Z", "start_pos": 44593812, "end_pos": 44593216, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022153.1", "url": "https://www.ensembl.org/id/ENSGALT00010022153.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012709.1", "url": "https://www.ensembl.org/id/ENSGALP00010012709.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425241", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425241", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AKH0-1", "protein_name": "DIRAS family GTPase 2", "gene_name": "DIRAS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVESSEAEALARKWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM", "length": 199 }, "evidence": [ { "id": "E1C055", "url": "https://omabrowser.org/oma/group/E1C055/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZKR8-1", "protein_name": "DIRAS family GTPase 2", "gene_name": "Diras2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "E1C055", "url": "https://omabrowser.org/oma/group/E1C055/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N2Q9-1", "protein_name": "DIRAS family GTPase 2", "gene_name": "DIRAS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVESSEAEVLARKWKCAFMETSAKLNLNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "E1C055", "url": "https://omabrowser.org/oma/group/E1C055/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HIA6-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "Diras2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVDSIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "E1C055", "url": "https://omabrowser.org/oma/group/E1C055/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5PR73-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "Diras2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPNREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVVM", "length": 199 }, "evidence": [ { "id": "E1C055", "url": "https://omabrowser.org/oma/group/E1C055/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HU8-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "DIRAS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM", "length": 199 }, "evidence": [ { "id": "E1C055", "url": "https://omabrowser.org/oma/group/E1C055/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VH66-1", "protein_name": "GTP-binding protein Di-Ras2", "gene_name": "Dmel\\CG8500", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTEQKNQVTRAAPEQSNDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGADIPNIPVMLVGNKCDETAELREVSQAEGQAQATTWSISFMETSAKTNHNVTELFQELLNMEKTRTVSLQLDTKKQKKQKKEKKSKDTNGSIPENGDAGASASGGAKEKCRVM", "length": 233 }, "evidence": [ { "id": "E1C055", "url": "https://omabrowser.org/oma/group/E1C055/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "E1C055", "url": "https://www.uniprot.org/uniprotkb/E1C055" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E1C055", "url": "https://www.uniprot.org/uniprotkb/E1C055" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C055", "url": "https://www.uniprot.org/uniprotkb/E1C055" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "E1C055", "url": "https://www.uniprot.org/uniprotkb/E1C055" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C064-1", "uniprot_ac": "E1C064", "uniprot_id": "E1C064_CHICK", "mass": { "chemical_mass": 38969.0, "monoisotopic_mass": 38969.0 }, "refseq": { "ac": "XP_426354", "name": "G-protein coupled receptor 78", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426354" }, "gene_names": [ { "name": "GPR78", "type": "recommended", "evidence": [ { "id": "E1C064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C064" } ] }, { "name": "GPR78", "type": "synonym", "evidence": [ { "id": "XP_426354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426354" } ] } ], "protein_names": [ { "name": "G-protein coupled receptor 26", "type": "recommended", "evidence": [ { "id": "E1C064", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C064/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 78", "type": "synonym", "evidence": [ { "id": "XP_426354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426354" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426354.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426354" } ] }, { "annotation": "Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.", "evidence": [ { "database": "UniProtKB", "id": "E1C064", "url": "https://www.uniprot.org/uniprotkb/E1C064#function" }, { "database": "UniProtKB", "id": "ARBA00056480", "url": "https://www.uniprot.org/uniprotkb/ARBA00056480#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C064", "url": "https://www.uniprot.org/uniprotkb/E1C064" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR78", "url": "https://www.uniprot.org/uniprotkb/E1C064", "locus": {} } ], "crossref": [ { "id": "E1C064", "url": "https://alphafold.ebi.ac.uk/entry/E1C064", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015595", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015595", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15219", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15219", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428798", "url": "https://www.ncbi.nlm.nih.gov/gene/428798", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428798", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428798", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DINRHWG", "url": "https://omabrowser.org/oma/group/DINRHWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C064", "url": "https://www.orthodb.org/?gene=E1C064", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24245:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24245:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426354", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C064", "url": "https://www.uniprot.org/uniprotkb/E1C064", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C064-1", "url": "https://www.uniprot.org/uniprotkb/E1C064-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLAGVLLALLLVLVLVVSLLSNLLVLLCFVYSTEIRKQVAGVFLVNLSFCNLLLTILNMPFTLLGILRNQQPLGGCICKAVGFLETFLTSNTMLSMAALSIDKWIAVVFPLSYTSKMRYKDAVILMGYSWLHSLTFPLVSLFYSWVDYNSVYASCTLHLKEETERRRFTVFTIVFHSTSFMLSLVILCFTYLKVLKVARFHCKRIDIITMQTLVLLVDIHPSVKQRCLNEQKRRRQRATKKISIFIGSFVICFGPYIITRLIELLPFVTINYYWGIISKCLTYSKAASDPFVYSLLRQQYKKVLINIVNRILKRDLYPSSGYNSSLDTENDYCLHRTN", "length": 339, "header": "tr|E1C064-1|E1C064_CHICK Isoform 1 of G-protein coupled receptor 26 OS=Gallus gallus OX=9031 GN=GPR78 PE=4 SV=2 CANONICAL=E1C064-1" }, "isoforms": [ { "isoform_ac": "E1C064-1", "url": "https://www.uniprot.org/uniprotkb/E1C064/entry#E1C064-1", "sequence": { "sequence": "MDLAGVLLALLLVLVLVVSLLSNLLVLLCFVYSTEIRKQVAGVFLVNLSFCNLLLTILNMPFTLLGILRNQQPLGGCICKAVGFLETFLTSNTMLSMAALSIDKWIAVVFPLSYTSKMRYKDAVILMGYSWLHSLTFPLVSLFYSWVDYNSVYASCTLHLKEETERRRFTVFTIVFHSTSFMLSLVILCFTYLKVLKVARFHCKRIDIITMQTLVLLVDIHPSVKQRCLNEQKRRRQRATKKISIFIGSFVICFGPYIITRLIELLPFVTINYYWGIISKCLTYSKAASDPFVYSLLRQQYKKVLINIVNRILKRDLYPSSGYNSSLDTENDYCLHRTN", "length": 339, "header": "tr|E1C064-1|E1C064_CHICK Isoform 1 of G-protein coupled receptor 26 OS=Gallus gallus OX=9031 GN=GPR78 PE=4 SV=2 CANONICAL=E1C064-1" }, "locus": { "chromosome": "4", "start_pos": 80675815, "end_pos": 80670760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041021.1", "url": "https://www.ensembl.org/id/ENSGALT00010041021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023985.1", "url": "https://www.ensembl.org/id/ENSGALP00010023985.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428798", 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"categories": [ "Protein Classification" ] }, { "id": "E1C0A1", "url": "https://www.orthodb.org/?gene=E1C0A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF413", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF413", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375280", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375280", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418555", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003641016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C0A1", "url": "https://www.uniprot.org/uniprotkb/E1C0A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0A1-1", "url": "https://www.uniprot.org/uniprotkb/E1C0A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSMNISRDFTDCSEFGNRSCSDSSRSPGVRGVLYFSIAAAFLVTVSGNMAIIFSILYFKQLHSPTNFLILSMAVTDFLLGFAIMPYSMVRSVENCWYFGMMFCKIHYSFDLMLCLVSIFHLCSIAVDRFYAICHPLHYASTMTMAAIKQITAVCWSVPAVFAFGVVFSEAHASGIEGYESLVKCSSLCPIMFNKAWGIVLFTIGLFAPACIMLGIYIKIFVVSQKHIRVLSQTHKHRKSDMKNELSKSKDKKAAKTLSVVMLAFLVCWFPCFFAILLDPFLNFSIPSPLFDALNWFGYLNSTCNPLIYGFFYPWFRKAFKYIVTGKIFNPQLRTTKLSSED", "length": 342, "header": "tr|E1C0A1-1|E1C0A1_CHICK Isoform 1 of Trace amine associated receptor 2 OS=Gallus gallus OX=9031 GN=TAAR2 PE=3 SV=2 CANONICAL=E1C0A1-1" }, "isoforms": [ { "isoform_ac": "E1C0A1-1", "url": "https://www.uniprot.org/uniprotkb/E1C0A1/entry#E1C0A1-1", "sequence": { "sequence": "MFSMNISRDFTDCSEFGNRSCSDSSRSPGVRGVLYFSIAAAFLVTVSGNMAIIFSILYFKQLHSPTNFLILSMAVTDFLLGFAIMPYSMVRSVENCWYFGMMFCKIHYSFDLMLCLVSIFHLCSIAVDRFYAICHPLHYASTMTMAAIKQITAVCWSVPAVFAFGVVFSEAHASGIEGYESLVKCSSLCPIMFNKAWGIVLFTIGLFAPACIMLGIYIKIFVVSQKHIRVLSQTHKHRKSDMKNELSKSKDKKAAKTLSVVMLAFLVCWFPCFFAILLDPFLNFSIPSPLFDALNWFGYLNSTCNPLIYGFFYPWFRKAFKYIVTGKIFNPQLRTTKLSSED", "length": 342, "header": "tr|E1C0A1-1|E1C0A1_CHICK Isoform 1 of Trace amine associated receptor 2 OS=Gallus gallus OX=9031 GN=TAAR2 PE=3 SV=2 CANONICAL=E1C0A1-1" }, "locus": { "chromosome": "3", "start_pos": 56518088, "end_pos": 56517063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010015201.1", "url": "https://www.ensembl.org/id/ENSGALT00010015201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010008934.1", "url": "https://www.ensembl.org/id/ENSGALP00010008934.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859322", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859322", "resource": "KEGG Pathway" }, { "id": "R-GGA-375280", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375280", "resource": "Reactome", "description": "Amine ligand-binding receptors" }, { "id": "R-GGA-418555", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418555", "resource": "Reactome", "description": "G alpha (s) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MJF8-1", "protein_name": "Trace amine associated receptor 2", "gene_name": "TAAR2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYSFMSGAIFITVFGNLAMIVSISYFKQLHTPTNFLILSMAVTDFLLGFTIMPYSMIRSVENCWYFGLTFCKIHYSFDLMLSITSIFHLCSVAIDRFYAICYPLQYSIKMTIPAIKQLLSLCWSVPGTFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFAPGSVMVGIYGKIFAVSRKHARAINNLPENQNNQMRKDKKAAKTLGIVMGVFLLCWFPCFFTILLDPFLSFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYIFLGKIFSSHFHNTNLFKEKETE", "length": 306 }, "evidence": [ { "id": "E1C0A1", "url": "https://omabrowser.org/oma/group/E1C0A1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5QD17-1", "protein_name": "Trace amine-associated receptor 2", "gene_name": "Taar2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFEAQQETFDCSEYGNGSCPENERSLGVRAAMYSLMACAIFITIFGNLAMIISISYFKQLHTPTNLLILSMAVTDFLLGFTIMPYSMVRSVENCWYFGLTFCKIHYSFDLMLSITSIFHLCSVAVDRFYAICHPLHYCTKMTIPVVRRLLLVCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFVAGFFTPSSMMVGIYGKIFAVSKKHARVIDNLPENQNNQMRKDKKAAKTLGIVMGVFLLCWFPCFFTILLDPFLNFSTPAVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSHFHNTNLFTQKETE", "length": 339 }, "evidence": [ { "id": "E1C0A1", "url": "https://omabrowser.org/oma/group/E1C0A1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD25-1", "protein_name": "Trace amine-associated receptor 2", "gene_name": "Taar2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSFEAQQETFDCSEYGNGSCPENERSLGVRAAMYSLMAGAIFITIFGNLVMIISISYFKQLHTPTNLLILSMAVTDFLLGFTIMPYSMVRSVENCWYFGLTFCKIHYSFDLMLSITSIFHLCSVAIDRFYAICHPLHYCTKMTIPVVKRLLLVCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFVAGFFTPSSMMVGIYGKIFAVSKKHARVIDNLPENQNNQMRKDKKAAKTLGIVMGVFLLCWFPCFFTILLDPFLNFSTPAILFDALTWFGYFNSTCNPLIYGFFYPWFRRALRYILLGKIFSSHFHNTNLFTQKETE", "length": 339 }, "evidence": [ { "id": "E1C0A1", "url": "https://omabrowser.org/oma/group/E1C0A1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P1P5-1", "protein_name": "Trace amine-associated receptor 2", "gene_name": "TAAR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFGNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNLRENQNNQVKKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE", "length": 351 }, "evidence": [ { "id": "E1C0A1", "url": "https://omabrowser.org/oma/group/E1C0A1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C0A1", "url": "https://www.uniprot.org/uniprotkb/E1C0A1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "E1C0A1", "url": "https://www.uniprot.org/uniprotkb/E1C0A1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "E1C0A1", "url": "https://www.uniprot.org/uniprotkb/E1C0A1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C0A1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 342, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C0A1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C0A1" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C0A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C0A1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 309, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C0I6-1", "uniprot_ac": "E1C0I6", "uniprot_id": "E1C0I6_CHICK", "mass": { "chemical_mass": 17890.0, "monoisotopic_mass": 17890.0 }, "refseq": { "ac": "XP_419336", "name": "F-box only protein 48", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419336" }, "gene_names": [ { "name": "FBXO48", "type": "recommended", "evidence": [ { "id": "E1C0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C0I6" } ] }, { "name": "FBXO48", "type": "synonym", "evidence": [ { "id": "XP_419336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419336" } ] } ], "protein_names": [ { "name": "F-box only protein 48", "type": "synonym", "evidence": [ { "id": "XP_419336", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419336" } ] }, { "name": "F-box protein 48", "type": "synonym", "evidence": [ { "id": "E1C0I6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C0I6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_419336.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419336" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C0I6", "url": "https://www.uniprot.org/uniprotkb/E1C0I6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO48", "url": "https://www.uniprot.org/uniprotkb/E1C0I6", "locus": { "chromosome": "3", "start_pos": 11539796, "end_pos": 11542852, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017849", "url": "https://www.ensembl.org/id/ENSGALG00010017849" } ] } } ], "crossref": [ { "id": "E1C0I6", "url": "https://alphafold.ebi.ac.uk/entry/E1C0I6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008753", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421265", "url": "https://www.ncbi.nlm.nih.gov/gene/421265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421265", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421265", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMCPMDA", "url": "https://omabrowser.org/oma/group/IMCPMDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C0I6", "url": "https://www.orthodb.org/?gene=E1C0I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12874", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12874", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12874:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12874:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_419336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419336", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C0I6", "url": "https://www.uniprot.org/uniprotkb/E1C0I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0I6-1", "url": "https://www.uniprot.org/uniprotkb/E1C0I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQKTPKRNKQPLTAGEPALLPPDKRRKGAPADFVALLPPEVSVQIFSSLDLRSLCSAAMTCRRWRLAIDGNDWLWRNHCLTVRAVCQREIDGDRGSGYSWKITLLRNYWKSKVKQEWLSGKYSNVHSQNNLPEKSMYPMDVDTWGEILEAELER", "length": 155, "header": "tr|E1C0I6-1|E1C0I6_CHICK Isoform 1 of F-box protein 48 OS=Gallus gallus OX=9031 GN=FBXO48 PE=4 SV=2 CANONICAL=E1C0I6-1" }, "isoforms": [ { "isoform_ac": "E1C0I6-1", "url": "https://www.uniprot.org/uniprotkb/E1C0I6/entry#E1C0I6-1", "sequence": { "sequence": "MMQKTPKRNKQPLTAGEPALLPPDKRRKGAPADFVALLPPEVSVQIFSSLDLRSLCSAAMTCRRWRLAIDGNDWLWRNHCLTVRAVCQREIDGDRGSGYSWKITLLRNYWKSKVKQEWLSGKYSNVHSQNNLPEKSMYPMDVDTWGEILEAELER", "length": 155, "header": "tr|E1C0I6-1|E1C0I6_CHICK Isoform 1 of F-box protein 48 OS=Gallus gallus OX=9031 GN=FBXO48 PE=4 SV=2 CANONICAL=E1C0I6-1" }, "locus": { "chromosome": "3", "start_pos": 11542411, "end_pos": 11540534, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043144.1", "url": "https://www.ensembl.org/id/ENSGALT00010043144.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025622.1", "url": "https://www.ensembl.org/id/ENSGALP00010025622.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421265", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421265", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SJ08-1", "protein_name": "F-box only protein", "gene_name": "FBXO48", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKNSQRNHHSRELSSEDAEKEKKENQNNFVELLPPEVTFKIFSQLDIRSLCRASMTCRSWNQTIRHSDSLWKPHCLTVRAVCQREIDDDLESGYPWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER", "length": 151 }, "evidence": [ { "id": "E1C0I6", "url": "https://omabrowser.org/oma/group/E1C0I6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3N250-1", "protein_name": "F-box only protein", "gene_name": "FBXO48", "tax_id": 9913, "organism": "Bos taurus", 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musculus", "sequence": { "sequence": "MKKTSKKNNNFKIPGTELNSADAERGKEESQRNFVELLPLEVTYKIFSQLDIQSLCRASRTCTGWNCAIRNNDSLWKPHCLTIRAVCQREIDDDIKSGYTWRVILLRNYQKSKVKYEWLSGRYSNIRSPVNLPEKAMCPMDADTWGEILDAELEREVEKLQ", "length": 161 }, "evidence": [ { "id": "E1C0I6", "url": "https://omabrowser.org/oma/group/E1C0I6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "R4GEA9-1", "protein_name": "F-box only protein 48 isoform a", "gene_name": "fbxo48", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVEGAAAPSAGQKLTRWCCSGLQDPLQIERDFSEALPAEMSVRIFGELDVRSLCRASVTCKHWNDIIEGSDHLWRSHCLTGLAVCRREVNGDRLDGCSWKVTLVRNYRKGCVKRRWLKGRYSNIRSADELPANSMCPLDVETWGEILEAELER", "length": 154 }, "evidence": [ { "id": "E1C0I6", "url": "https://omabrowser.org/oma/group/E1C0I6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": 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"https://www.uniprot.org/uniprotkb/E1C0I6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E1C0I6", "url": "https://www.uniprot.org/uniprotkb/E1C0I6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C0I6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 155, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C0I6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C0I6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C0L7-1", "uniprot_ac": "E1C0L7", "uniprot_id": "E1C0L7_CHICK", "mass": { "chemical_mass": 34261.0, "monoisotopic_mass": 34261.0 }, "refseq": { "ac": "XP_004945277", "name": "RNA pseudouridylate synthase domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945277" }, "gene_names": [ { "name": "RPUSD1", "type": "recommended", "evidence": [ { "id": "E1C0L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C0L7" } ] }, { "name": "RPUSD1", "type": "synonym", "evidence": [ { "id": "XP_004945277", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945277" } ] } ], "protein_names": [ { "name": "RNA pseudouridine synthase domain containing 1", "type": "synonym", "evidence": [ { "id": "E1C0L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C0L7/entry#names_and_taxonomy" } ] }, { "name": "RNA pseudouridylate synthase domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004945277", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945277" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945277" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C0L7", "url": "https://www.uniprot.org/uniprotkb/E1C0L7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPUSD1", "url": "https://www.uniprot.org/uniprotkb/E1C0L7", "locus": { "chromosome": "14", "start_pos": 5998946, "end_pos": 5995472, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018513", "url": "https://www.ensembl.org/id/ENSGALG00010018513" } ] } } ], "crossref": [ { "id": "E1C0L7", "url": "https://alphafold.ebi.ac.uk/entry/E1C0L7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005315", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005315", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771031", "url": "https://www.ncbi.nlm.nih.gov/gene/771031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "E1C0L7", "url": "https://www.orthodb.org/?gene=E1C0L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21600", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21600", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21600:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21600:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945277", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C0L7", "url": "https://www.uniprot.org/uniprotkb/E1C0L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0L7-1", "url": "https://www.uniprot.org/uniprotkb/E1C0L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPGTIDNLCILYQSPDFIVVNKHWDIRIDSKMWYETLTLQSQLKHRFPELADPDTYYGFRFCHQLDFSTSGALCVALNKAAAGSAYKCFKDRLVTKAYLALVRGHVDQSRMTIRYAIGKNTVEGMTHMMCIEGTEGCENPKPCQSELIVLEHGSYSGDPVTKVLLQPLTGRTHQLRVHCSAIGHPIVGDFTYSHKKDSGPYRMMLHAYYLRIPTSKELIEVCAPDPFVTALDGNWVPQRVVHRLDETIQELKDKAVQKGDVGQSQQAMPGDKGEEALSKAKSPELEEQRVQCEQWLAEWALE", "length": 303, "header": "tr|E1C0L7-1|E1C0L7_CHICK Isoform 1 of RNA pseudouridine synthase domain containing 1 OS=Gallus gallus OX=9031 GN=RPUSD1 PE=3 SV=4 CANONICAL=E1C0L7-1" }, "isoforms": [ { "isoform_ac": "E1C0L7-1", "url": "https://www.uniprot.org/uniprotkb/E1C0L7/entry#E1C0L7-1", "sequence": { "sequence": "MEPGTIDNLCILYQSPDFIVVNKHWDIRIDSKMWYETLTLQSQLKHRFPELADPDTYYGFRFCHQLDFSTSGALCVALNKAAAGSAYKCFKDRLVTKAYLALVRGHVDQSRMTIRYAIGKNTVEGMTHMMCIEGTEGCENPKPCQSELIVLEHGSYSGDPVTKVLLQPLTGRTHQLRVHCSAIGHPIVGDFTYSHKKDSGPYRMMLHAYYLRIPTSKELIEVCAPDPFVTALDGNWVPQRVVHRLDETIQELKDKAVQKGDVGQSQQAMPGDKGEEALSKAKSPELEEQRVQCEQWLAEWALE", "length": 303, "header": "tr|E1C0L7-1|E1C0L7_CHICK Isoform 1 of RNA pseudouridine synthase domain containing 1 OS=Gallus gallus OX=9031 GN=RPUSD1 PE=3 SV=4 CANONICAL=E1C0L7-1" }, "locus": { "chromosome": "14", "start_pos": 5997608, "end_pos": 5995671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044787.1", "url": "https://www.ensembl.org/id/ENSGALT00010044787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026709.1", "url": "https://www.ensembl.org/id/ENSGALP00010026709.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "enzyme-directed rRNA pseudouridine synthesis", "id": "GO:0000455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000455", "evidence": [ { "database": "UniProtKB", "id": "E1C0L7", "url": "https://www.uniprot.org/uniprotkb/E1C0L7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, 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"XP_015135154", "name": "myb/SANT-like DNA-binding domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135154" }, "gene_names": [ { "name": "MSANTD4", "type": "recommended", "evidence": [ { "id": "E1C0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C0N5" } ] }, { "name": "MSANTD4", "type": "synonym", "evidence": [ { "id": "XP_015135154", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135154" } ] } ], "protein_names": [ { "name": "Myb/SANT DNA binding domain containing 4 with coiled-coils", "type": "synonym", "evidence": [ { "id": "E1C0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C0N5/entry#names_and_taxonomy" } ] }, { "name": "myb/SANT-like DNA-binding domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "XP_015135154", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135154" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015135154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135154" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C0N5", "url": "https://www.uniprot.org/uniprotkb/E1C0N5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSANTD4", "url": "https://www.uniprot.org/uniprotkb/E1C0N5", "locus": { "chromosome": "1", "start_pos": 181016378, "end_pos": 181002891, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005191", "url": "https://www.ensembl.org/id/ENSGALG00010005191" } ] } } ], "crossref": [ { "id": "E1C0N5", "url": "https://alphafold.ebi.ac.uk/entry/E1C0N5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017177", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017177", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418977", "url": "https://www.ncbi.nlm.nih.gov/gene/418977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418977", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418977", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WLKANIK", "url": "https://omabrowser.org/oma/group/WLKANIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C0N5", "url": "https://www.orthodb.org/?gene=E1C0N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21732:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21732:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015135154", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015135154", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C0N5", "url": "https://www.uniprot.org/uniprotkb/E1C0N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C0N5-1", "url": "https://www.uniprot.org/uniprotkb/E1C0N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C123-1", "uniprot_ac": "E1C123", "uniprot_id": "E1C123_CHICK", "mass": { "chemical_mass": 38045.0, "monoisotopic_mass": 38045.0 }, "refseq": { "ac": "XP_421292", "name": "activator of 90 kDa heat shock protein ATPase homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421292" }, "gene_names": [ { "name": "AHSA1", "type": "recommended", "evidence": [ { "id": "E1C123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ] }, { "name": "AHSA1", "type": "synonym", "evidence": [ { "id": "XP_421292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421292" } ] } ], "protein_names": [ { "name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "type": "recommended", "evidence": [ { "id": "E1C123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C123/entry#names_and_taxonomy" } ] }, { "name": "activator of 90 kDa heat shock protein ATPase homolog 1", "type": "synonym", "evidence": [ { "id": "XP_421292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421292" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421292" } ] }, { "annotation": "Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins.", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123#function" }, { "database": "UniProtKB", "id": "ARBA00054704", "url": "https://www.uniprot.org/uniprotkb/ARBA00054704#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AHSA1", "url": "https://www.uniprot.org/uniprotkb/E1C123", "locus": { "chromosome": "5", "start_pos": 38746051, "end_pos": 38740317, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005335", "url": "https://www.ensembl.org/id/ENSGALG00010005335" } ] } } ], "crossref": [ { "id": "E1C123", "url": "https://alphafold.ebi.ac.uk/entry/E1C123", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010463", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010463", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08892", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08892", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423378", "url": "https://www.ncbi.nlm.nih.gov/gene/423378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423378", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIAMKWR", "url": "https://omabrowser.org/oma/group/HIAMKWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C123", "url": "https://www.orthodb.org/?gene=E1C123", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13009", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13009", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13009:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13009:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421292", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C123-1", "url": "https://www.uniprot.org/uniprotkb/E1C123-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKWGEGDPRWIVEQRADATNVNNWHWTERDASNWSTERLKALLLPVRVEGEEGACEVTEVSKLDGEASINNRKGKLIFFYEWAIKLAWTGTSTTGVKYKGYVEIPNLSDENDVDEVEILVSLAKDEPDTNLKTLMKQEGAKKIRDAIKTYISTLKTEFTQGMILPTVNGEHMETAPQVAPKAKDSKTAASSSTATAQSKSIGVKIPTCKIILKDTFLTSPEELYRVFVTQEMVQAFTHAHAALEADKGGKFQLLDGSVTGEFVDLVPEKQLVMKWRFKSWPAGHFATITLNFTDKGGETEVCLEGKGIPASEEERTKQGWQRYYFEGIKQTFGYGARLF", "length": 340, "header": "tr|E1C123-1|E1C123_CHICK Isoform 1 of Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Gallus gallus OX=9031 GN=AHSA1 PE=1 SV=1 CANONICAL=E1C123-1" }, "isoforms": [ { "isoform_ac": "E1C123-1", "url": "https://www.uniprot.org/uniprotkb/E1C123/entry#E1C123-1", "sequence": { "sequence": "MAKWGEGDPRWIVEQRADATNVNNWHWTERDASNWSTERLKALLLPVRVEGEEGACEVTEVSKLDGEASINNRKGKLIFFYEWAIKLAWTGTSTTGVKYKGYVEIPNLSDENDVDEVEILVSLAKDEPDTNLKTLMKQEGAKKIRDAIKTYISTLKTEFTQGMILPTVNGEHMETAPQVAPKAKDSKTAASSSTATAQSKSIGVKIPTCKIILKDTFLTSPEELYRVFVTQEMVQAFTHAHAALEADKGGKFQLLDGSVTGEFVDLVPEKQLVMKWRFKSWPAGHFATITLNFTDKGGETEVCLEGKGIPASEEERTKQGWQRYYFEGIKQTFGYGARLF", "length": 340, "header": "tr|E1C123-1|E1C123_CHICK Isoform 1 of Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Gallus gallus OX=9031 GN=AHSA1 PE=1 SV=1 CANONICAL=E1C123-1" }, "locus": { "chromosome": "5", "start_pos": 38745557, "end_pos": 38740382, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010012652.1", "url": "https://www.ensembl.org/id/ENSGALT00010012652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007216.1", "url": "https://www.ensembl.org/id/ENSGALP00010007216.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423378", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1T4G7-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "AHSA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTDKLKTLFLAVRVQNEEGKCEVTEVNKLDGEASINNRKGKLIFFYEWSIKLNWTGTSKSGVQYKGHVDIPNLSDENSVDEVEISVSLAKDEPDTNLVALMKEEGVRLLREAMGIYISTLKTEFTQGMILPTMNGESVDPAGQPALKTEERKAKSAPSKTQARPVGVKIPTCKITLRETFLTSPEELYRVFTNQELVQAFTHAPAMLEADKGGKFHLVDGNVSGEFTDLVPEKHIVMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGVPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "length": 338 }, "evidence": [ { "id": "E1C123", "url": "https://omabrowser.org/oma/group/E1C123/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B0BN63-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "Ahsa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSGVQYKGHVEIPNLSDENSVDEVEISVSLAKDEPDTSLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTEVCKAKCAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "length": 338 }, "evidence": [ { "id": "E1C123", "url": "https://omabrowser.org/oma/group/E1C123/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H638-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "Ahsa1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSGVQYKGHVEIPNLSDENSVDEVEISVSLAKDEPDTNLVALMKEEGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVEPVSQPAPKTEVCKAKSAPSKSQAKPVGVKIPTCKISLRETFLTSPEELYRVFTTQELVQAFTHAPAALEADKGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETEVCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "length": 338 }, "evidence": [ { "id": "E1C123", "url": "https://omabrowser.org/oma/group/E1C123/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95433-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "AHSA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTDKLKTLFLAVQVQNEEGKCEVTEVSKLDGEASINNRKGKLIFFYEWSVKLNWTGTSKSGVQYKGHVEIPNLSDENSVDEVEISVSLAKDEPDTNLVALMKEEGVKLLREAMGIYISTLKTEFTQGMILPTMNGESVDPVGQPALKTEERKAKPAPSKTQARPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPATLEADRGGKFHMVDGNVSGEFTDLVPEKHIVMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "length": 338 }, "evidence": [ { "id": "E1C123", "url": "https://omabrowser.org/oma/group/E1C123/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55DB6-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog", "gene_name": "ahsa", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAKVGEGDPRWIVENREDGHNVNGWHWSEKDCLPWSKNTIGGLFDKKVIQETDEYTFKISSTPVVSGECTANNRKGKTIFLYELDVKMNWEVVFKPKKVLPPPPTTKSKGAADDIDEEDDDGKPAEPIITQKKTISGEFTVPYISDENGDEAPTVRYTINTTADNDETKQSINMVQSLLKSHGVPFVQSQCQEFIKLLKKEFVSKKQVEQSQQQQTANTTTNTTTTTNTVPKVTSSTVIFNSTPTKKPTTKTLKLKEEFQCSPMDAYDVFVNINKLRAFTQSDCTFENEEGGKFSLYGGSIQGVNKTLSPGSKIVQTWRLDNWSKGVESQVTITFSVDGKPLTNVEIVQTGIPIDEFEKTEEGWKRNILDRIKHTFSYSSKIF", "length": 383 }, "evidence": [ { "id": "E1C123", "url": "https://omabrowser.org/oma/group/E1C123/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BK64-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "Ahsa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKWGEGDPRWIVEERADATNVNNWHWTERDASNWSTEKLKTLFLAVRVENEEGKCEVTEVNKLDGEASINNRKGKLIFFYEWTIKLNWTGTSKSGVQYKGHVEIPNLSDENSVDEVEISVSLAKDEPDTNLVALMKEDGVKLLREAVGIYISTLKTEFTQGMILPTVNGESVDPVGQPALKTETCKAKSAPSKSQAKPVGVKIPTCKITLKETFLTSPEELYRVFTTQELVQAFTHAPAALEADRGGKFHMVDGNVTGEFTDLVPEKHIAMKWRFKSWPEGHFATITLTFIDKNGETELCMEGRGIPAPEEERTRQGWQRYYFEGIKQTFGYGARLF", "length": 338 }, "evidence": [ { "id": "E1C123", "url": "https://omabrowser.org/oma/group/E1C123/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" }, { "name": "protein folding chaperone", "id": "GO:0044183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044183", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" }, { "name": "maintenance of unfolded protein", "id": "GO:0036506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036506", "evidence": [ { "database": "UniProtKB", "id": "E1C123", "url": "https://www.uniprot.org/uniprotkb/E1C123" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C123-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 340, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C123-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C123" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C123" }, { "id": "SM01000", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01000" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Activator of Hsp90 ATPase AHSA1-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 161, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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"E1C195-1", "url": "https://www.uniprot.org/uniprotkb/E1C195-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKDFRYYFQHPWSRLVVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPESGGWRCLKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNLFLIMAGNMSAYIITDFMGIRNENFMKVAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVEVNLPGLPSAHMQFKVPYFQKILKEEYHIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNNTNPLTNRTYAEGDMFLHSRYIGSSLDVKCLAFIPSLLAFALFGFFIWFFGRFQKTDQGMENLDKSYTRMKRKSPSDMGMTRENTQVLVEEPSSFQEPHLVSIKSDLSEIVFNSSLLTSENLNAQLSEQDSPLQPVPESVVPKSNPTT", "length": 512, "header": "tr|E1C195-1|E1C195_CHICK Isoform 1 of Transmembrane protein 117 OS=Gallus gallus OX=9031 GN=TMEM117 PE=4 SV=3 CANONICAL=E1C195-1" }, "isoforms": [ { "isoform_ac": "A0A8V0X432-1", "url": "https://www.uniprot.org/uniprotkb/E1C195/entry#A0A8V0X432-1", "sequence": { "sequence": "MDKDFRYYFQHPWSRLVVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPESGGWRCLKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNLFLIMAGNMSAYIITDFMGIRNENFMKVAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVEVNLPGLPSAHMQFKVPYFQKILKEEYHIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNNTNPLTNRTYAEGDMFLHSRYIGSSLDVKCLAFIPSLLAFALFGFFIWFFGRFQKTDQGMENLDKSYTRMKRKSPSDMGMTRENTQVLVEEPSSFQEPHLLEHHNLTSLFTHLWSQ", "length": 480, "header": "tr|A0A8V0X432-1|A0A8V0X432_CHICK Computationally mapped isoform of Transmembrane protein 117 OS=Gallus gallus OX=9031 GN=TMEM117 PE=4 SV=1 CANONICAL=E1C195-1" }, "locus": { "chromosome": "1", "start_pos": 30449190, "end_pos": 30256364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004371.1", "url": "https://www.ensembl.org/id/ENSGALT00010004371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002648.1", "url": "https://www.ensembl.org/id/ENSGALP00010002648.1" } ] } }, { "isoform_ac": "E1C195-1", "url": "https://www.uniprot.org/uniprotkb/E1C195/entry#E1C195-1", "sequence": { "sequence": "MDKDFRYYFQHPWSRLVVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPESGGWRCLKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNLFLIMAGNMSAYIITDFMGIRNENFMKVAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVEVNLPGLPSAHMQFKVPYFQKILKEEYHIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNNTNPLTNRTYAEGDMFLHSRYIGSSLDVKCLAFIPSLLAFALFGFFIWFFGRFQKTDQGMENLDKSYTRMKRKSPSDMGMTRENTQVLVEEPSSFQEPHLVSIKSDLSEIVFNSSLLTSENLNAQLSEQDSPLQPVPESVVPKSNPTT", "length": 512, "header": "tr|E1C195-1|E1C195_CHICK Isoform 1 of Transmembrane protein 117 OS=Gallus gallus OX=9031 GN=TMEM117 PE=4 SV=3 CANONICAL=E1C195-1" }, "locus": { "chromosome": "1", "start_pos": 30448680, "end_pos": 30256364, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010004373.1", "url": "https://www.ensembl.org/id/ENSGALT00010004373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010002650.1", "url": "https://www.ensembl.org/id/ENSGALP00010002650.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417798", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417798", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B6X6-1", "protein_name": "Transmembrane protein 117", "gene_name": "TMEM117", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRLLKVLLWLLAILIGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYHIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEQGMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPALVCIRSDFNEIVYKSSHLTSENLSSHLNESTSATEADPEPTTSKSTPTN", "length": 514 }, "evidence": [ { "id": "E1C195", "url": "https://omabrowser.org/oma/group/E1C195/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LWX9-1", "protein_name": "Transmembrane protein 117", "gene_name": "Tmem117", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILIGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTVLLMDGNMGAYLITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPHTNKTYVEGDMFLHSRFTGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEQGMENQDKTYTRMKRKSPSEHSKDMGITRESTQVSVEDPLNDPPLVCIRSDFNEIVYKSSHLTSENLSLHLKESTSAAEADQDPAASPSLRTD", "length": 514 }, "evidence": [ { "id": "E1C195", "url": "https://omabrowser.org/oma/group/E1C195/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BH18-1", "protein_name": "Transmembrane protein 117", "gene_name": "Tmem117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILIGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTILLMDGNMGAYLITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPQTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEQGMENQDKTYTRMKRKSPSEHSKDMGITRENTQVSVEDPLNDPALVCIRSDFNEIVYKSSHLTSENLSLHLKESTSEVEAEQEPAASQRMRTN", "length": 514 }, "evidence": [ { "id": "E1C195", "url": "https://omabrowser.org/oma/group/E1C195/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0C3-1", "protein_name": "Transmembrane protein 117", "gene_name": "TMEM117", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKDFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPRGVGWRILKVLLWLLAILTGLIAGKFLFHQRLFGQLLRLKMFREDHGSWMTMFFSTILFLFIFSHIYNTILLMDGNMGAYIITDYMGIRNESFMKLAAVGTWMGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPSLIAFVWFGFFIWFFGRFLKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSENLSSQLNESTSATEADQDPTTSKSTPTN", "length": 514 }, "evidence": [ { "id": "E1C195", "url": "https://omabrowser.org/oma/group/E1C195/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "E1C195", "url": "https://www.uniprot.org/uniprotkb/E1C195" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C195", "url": "https://www.uniprot.org/uniprotkb/E1C195" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "id": "GO:0070059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070059", "evidence": [ { "database": "UniProtKB", "id": "E1C195", "url": "https://www.uniprot.org/uniprotkb/E1C195" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 353, "end_pos": 355, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C195-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 512, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C195-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C195" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 353, "end_pos": 355 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 477, "end_pos": 479 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C196-1", "uniprot_ac": "E1C196", "uniprot_id": "E1C196_CHICK", "mass": { "chemical_mass": 50527.0, "monoisotopic_mass": 50527.0 }, "refseq": { "ac": "NP_001182086", "name": "putative short-chain dehydrogenase/reductase family 42E member 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182086" }, "gene_names": [ { "name": "SDR42E2", "type": "recommended", "evidence": [ { "id": "E1C196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C196" } ] }, { "name": "SDR42E2", "type": "synonym", "evidence": [ { "id": "NP_001182086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182086" } ] } ], "protein_names": [ { "name": "Short chain dehydrogenase/reductase family 42E, member 2", "type": "synonym", "evidence": [ { "id": "E1C196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C196/entry#names_and_taxonomy" } ] }, { "name": "putative short-chain dehydrogenase/reductase family 42E member 2", "type": "synonym", "evidence": [ { "id": "NP_001182086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182086" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMN05341171 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Aug 26, 2010 this sequence version replaced XP_414919.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001182086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182086" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C196", "url": "https://www.uniprot.org/uniprotkb/E1C196" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SDR42E2", "url": "https://www.uniprot.org/uniprotkb/E1C196", "locus": { "chromosome": "14", "start_pos": 8654353, "end_pos": 8644319, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017855", "url": "https://www.ensembl.org/id/ENSGALG00010017855" } ] } } ], "crossref": [ { "id": "E1C196", "url": "https://alphafold.ebi.ac.uk/entry/E1C196", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006964", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006964", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416618", "url": "https://www.ncbi.nlm.nih.gov/gene/416618", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416618", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416618", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PWLNRSW", "url": "https://omabrowser.org/oma/group/PWLNRSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C196", "url": "https://www.orthodb.org/?gene=E1C196", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43245:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43245:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001182086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C196", "url": "https://www.uniprot.org/uniprotkb/E1C196", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C196-1", "url": "https://www.uniprot.org/uniprotkb/E1C196-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLAGIVCIGEHYGAIFNMEKKLLCASGHRGHYFSDRKLPVSEAANPWHQPPSSGVRGNAGALKDKAMRAVVTGGGGYFGYKLGCALASSGASVVLYDIHKPIWEIPNGVVCIQADVRDYDAVFAACEGADCVFHVASYGMSGREQLHREEIETVNINGTRFIIDACKQRNITRLIYTSTVNVVFGGLPIEDGDEETVPYFPIEKHVDHYSRTKSIAEQMVLAANGTPLAGGGVLYTSVLRPPGIYGPEEQRHLPRLAKNIERGILSFKFGDPSAKMNWVHVENLVQAQILAAEALTPEKNYIASGQVYFIHDGEKFNLFEWLAPLFERLGCSKPWIPIPTSLVYASATVMEHLHLILKPLVELSPLLTRNEVQNISTTHTFRIDKARRQLGYSPEKFTFADSVEHYIKTRAEARSEHGFPRVMLLFLAILSLIFLSLRFDDLSVLHFFKEAQH", "length": 454, "header": "tr|E1C196-1|E1C196_CHICK Isoform 1 of Short chain dehydrogenase/reductase family 42E, member 2 OS=Gallus gallus OX=9031 GN=SDR42E2 PE=3 SV=2 CANONICAL=E1C196-1" }, "isoforms": [ { "isoform_ac": "E1C196-1", "url": "https://www.uniprot.org/uniprotkb/E1C196/entry#E1C196-1", "sequence": { "sequence": "MKLAGIVCIGEHYGAIFNMEKKLLCASGHRGHYFSDRKLPVSEAANPWHQPPSSGVRGNAGALKDKAMRAVVTGGGGYFGYKLGCALASSGASVVLYDIHKPIWEIPNGVVCIQADVRDYDAVFAACEGADCVFHVASYGMSGREQLHREEIETVNINGTRFIIDACKQRNITRLIYTSTVNVVFGGLPIEDGDEETVPYFPIEKHVDHYSRTKSIAEQMVLAANGTPLAGGGVLYTSVLRPPGIYGPEEQRHLPRLAKNIERGILSFKFGDPSAKMNWVHVENLVQAQILAAEALTPEKNYIASGQVYFIHDGEKFNLFEWLAPLFERLGCSKPWIPIPTSLVYASATVMEHLHLILKPLVELSPLLTRNEVQNISTTHTFRIDKARRQLGYSPEKFTFADSVEHYIKTRAEARSEHGFPRVMLLFLAILSLIFLSLRFDDLSVLHFFKEAQH", "length": 454, "header": "tr|E1C196-1|E1C196_CHICK Isoform 1 of Short chain dehydrogenase/reductase family 42E, member 2 OS=Gallus gallus OX=9031 GN=SDR42E2 PE=3 SV=2 CANONICAL=E1C196-1" }, "locus": { "chromosome": "14", "start_pos": 8653888, "end_pos": 8645242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043162.1", "url": "https://www.ensembl.org/id/ENSGALT00010043162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025635.1", "url": "https://www.ensembl.org/id/ENSGALP00010025635.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416618", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416618", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O22813-1", "protein_name": "NAD(P)-binding Rossmann-fold superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MHLSENEGVEGNTFVVTGGLGFVGAALCLELVRRGARQVRSFDLRHSSPWSDDLKNSGVRCIQGDVTKKQDVDNALDGADCVLHLASYGMSGKEMLRFGRCDEVNINGTCNVLEAAFKHEITRIVYVSTYNVVFGGKEILNGNEGLPYFPLDDHVDAYSRTKSIAEQLVLKSNGRPFKNGGKRMYTCAIRPAAIYGPGEDRHLPRIVTLTKLGLALFKIGEPSVKSDWIYVENLVLAIILASMGLLDDIPGREGQPVAAGQPYFVSDGYPVNTFEFLRPLLKSLDYDLPKCTISVPFALSLGKIFQGFYTVLYPWLSKSWLPQPLVLPAEVYKVGVTHYFSYLKAKEELGYVPFKSSKEGMAATISYWQERKRRSLDGPTMFTWIAVTIGMSALFAAGWLPDIGPVPFLRAIHLFFFRTITIVKAVFIVAVVLHVAEGIYAWFLAKRVDPGNAMGWFLQTSALGFFSMRFLLKRAKEHQI", "length": 480 }, "evidence": [ { "id": "E1C196", "url": "https://omabrowser.org/oma/group/E1C196/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "steroid biosynthetic process", "id": "GO:0006694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006694", "evidence": [ { "database": "UniProtKB", "id": "E1C196", "url": "https://www.uniprot.org/uniprotkb/E1C196" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "E1C196", "url": "https://www.uniprot.org/uniprotkb/E1C196" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C196-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 454, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C196-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C196" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C196" }, { "id": "PF01073", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01073" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "3-beta hydroxysteroid dehydrogenase/isomerase", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 335, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 375, "end_pos": 377 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1A2-1", "uniprot_ac": "E1C1A2", "uniprot_id": "E1C1A2_CHICK", "mass": { "chemical_mass": 43616.0, "monoisotopic_mass": 43616.0 }, "refseq": { "ac": "XP_003641566", "name": "cyclin-J isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641566" }, "gene_names": [ { "name": "CCNJ", "type": "recommended", "evidence": [ { "id": "E1C1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ] }, { "name": "CCNJ", "type": "synonym", "evidence": [ { "id": "XP_003641566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641566" } ] } ], "protein_names": [ { "name": "Cyclin-J", "type": "recommended", "evidence": [ { "id": "E1C1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1A2/entry#names_and_taxonomy" } ] }, { "name": "cyclin-J isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003641566", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641566" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641566" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNJ", "url": "https://www.uniprot.org/uniprotkb/E1C1A2", "locus": { "chromosome": "6", "start_pos": 21831447, "end_pos": 21841252, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021633", "url": "https://www.ensembl.org/id/ENSGALG00010021633" } ] } } ], "crossref": [ { "id": "E1C1A2", "url": "https://alphafold.ebi.ac.uk/entry/E1C1A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006955", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006955", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20528", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20528", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423821", "url": "https://www.ncbi.nlm.nih.gov/gene/423821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423821", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423821", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLMQCIE", "url": "https://omabrowser.org/oma/group/FLMQCIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL35", "url": "https://www.orthodb.org/?gene=A0A8V0ZL35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZRQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1A2", "url": "https://www.orthodb.org/?gene=E1C1A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641566", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1A2-1", "url": "https://www.uniprot.org/uniprotkb/E1C1A2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELEAQWWTGQLAADIHQALRYKELKLPSYKGQSPQLHLRRYFADLIAIVSNRFRLCPAARHLAVYLLDLFMDRYDISIQQLHVVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIDYYLSIAVHETDLHDGWPMVCLEKTKLYMAKYADYFLEVSLQDHAFLNYAPSLVATACVASSRIILRLSPTWPTRLHHLTAYSWDFLVPCIERLLIAHDNDVKEANKQKGQHAQSAQHTVFQTPGPTAQQANVQPHIPQYLQAHQSSLQYHHQTSQQQNCQQIVSANHTASYPLQTCPAALQSSVQARSHVQTGAAMSLAVPLEVKPCISVSYNRSYQVNGRYSCVTPCFER", "length": 383, "header": "tr|E1C1A2-1|E1C1A2_CHICK Isoform 1 of Cyclin-J OS=Gallus gallus OX=9031 GN=CCNJ PE=3 SV=2 CANONICAL=E1C1A2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZL35-1", "url": "https://www.uniprot.org/uniprotkb/E1C1A2/entry#A0A8V0ZL35-1", "sequence": { "sequence": "RPRPRRAAPHGAGGAVVDRTAGGGHPPGAALQDHAFLNYAPSLVATACVASSRIILRLSPTWPTRLHHLTAYSWDFLVPCIERLLIAHDNDVKEANKQKGQHAQSAQHTVFQTPGPTAQQANVQPHIPQYLQAHQSSLQYHHQTSQQQNCQQIVSANHTASYPLQTCPAALQSSVQARSHVQTGAAMSLAVPLEVKPCISVSYNRSYQVNGRYSCVTPCFER", "length": 222, "header": "tr|A0A8V0ZL35-1|A0A8V0ZL35_CHICK Computationally mapped isoform of Cyclin J OS=Gallus gallus OX=9031 GN=CCNJ PE=4 SV=1 CANONICAL=E1C1A2-1" }, "locus": { "chromosome": "6", "start_pos": 21840696, "end_pos": 21834142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052541.1", "url": "https://www.ensembl.org/id/ENSGALT00010052541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031447.1", "url": "https://www.ensembl.org/id/ENSGALP00010031447.1" } ] } }, { "isoform_ac": "A0A8V0ZRQ3-1", "url": "https://www.uniprot.org/uniprotkb/E1C1A2/entry#A0A8V0ZRQ3-1", "sequence": { "sequence": "MELEAQWWTGQLAADIHQALRYKELKLPSYKGQSPQLHLRRYFADLIAIVSNRFRLCPAARHLAVYLLDLFMDRYDISIQQLHVVALSCLLLANHAFLNYAPSLVATACVASSRIILRLSPTWPTRLHHLTAYSWDFLVPCIERLLIAHDNDVKEANKQKGQHAQSAQHTVFQTPGPTAQQANVQPHIPQYLQAHQSSLQYHHQTSQQQNCQQIVSANHTASYPLQTCPAALQSSVQARSHVQTGAAMSLAVPLEVKPCISVSYNRSYQVNGRYSCVTPCFER", "length": 283, "header": "tr|A0A8V0ZRQ3-1|A0A8V0ZRQ3_CHICK Computationally mapped isoform of Cyclin J OS=Gallus gallus OX=9031 GN=CCNJ PE=4 SV=1 CANONICAL=E1C1A2-1" }, "locus": { "chromosome": "6", "start_pos": 21840668, "end_pos": 21834142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052549.1", "url": "https://www.ensembl.org/id/ENSGALT00010052549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031455.1", "url": "https://www.ensembl.org/id/ENSGALP00010031455.1" } ] } }, { "isoform_ac": "E1C1A2-1", "url": "https://www.uniprot.org/uniprotkb/E1C1A2/entry#E1C1A2-1", "sequence": { "sequence": "MELEAQWWTGQLAADIHQALRYKELKLPSYKGQSPQLHLRRYFADLIAIVSNRFRLCPAARHLAVYLLDLFMDRYDISIQQLHVVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIDYYLSIAVHETDLHDGWPMVCLEKTKLYMAKYADYFLEVSLQDHAFLNYAPSLVATACVASSRIILRLSPTWPTRLHHLTAYSWDFLVPCIERLLIAHDNDVKEANKQKGQHAQSAQHTVFQTPGPTAQQANVQPHIPQYLQAHQSSLQYHHQTSQQQNCQQIVSANHTASYPLQTCPAALQSSVQARSHVQTGAAMSLAVPLEVKPCISVSYNRSYQVNGRYSCVTPCFER", "length": 383, "header": "tr|E1C1A2-1|E1C1A2_CHICK Isoform 1 of Cyclin-J OS=Gallus gallus OX=9031 GN=CCNJ PE=3 SV=2 CANONICAL=E1C1A2-1" }, "locus": { "chromosome": "6", "start_pos": 21840668, "end_pos": 21834142, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052546.1", "url": "https://www.ensembl.org/id/ENSGALT00010052546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031452.1", "url": "https://www.ensembl.org/id/ENSGALP00010031452.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 278, "start_aa": "Thr", "end_pos": 278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr278", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 378, "start_aa": "Thr", "end_pos": 378, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr378", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423821", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423821", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BF22-1", "protein_name": "Cyclin-J", "gene_name": "CCNJ", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELEAQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMMCLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRGQAGPQPAQLSVFQAASQPSRAVHFQQPQYLHQTHQTSLQYRHPVSEQPSCQQIVSTTHTSSYTLPTCPAGFQTSVQGLGHVPAGVGMSLAIPVEVKPCLNVSYNRSYQINEHYPCITQCFER", "length": 383 }, "evidence": [ { "id": "E1C1A2", "url": "https://omabrowser.org/oma/group/E1C1A2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TZI6-1", "protein_name": "Cyclin-J", "gene_name": "Ccnj", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLNLRRYFADLIAIVSNRFTLCPPARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQTLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMVCLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLLAHDNDVKEANKQRGQSAPQSTQLTVFQTAQPSRPVHFQQPQYLHQSSLQYRHPVSEQPSRQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINEHFPCITPCFER", "length": 379 }, "evidence": [ { "id": "E1C1A2", "url": "https://omabrowser.org/oma/group/E1C1A2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T5M9-1", "protein_name": "Cyclin-J", "gene_name": "CCNJ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLSLRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTSLQYRHPTSEQPSCQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINEHYPCITPCFER", "length": 372 }, "evidence": [ { "id": "E1C1A2", "url": "https://omabrowser.org/oma/group/E1C1A2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "E1C1A2", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1A2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 383, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1A2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1A2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" }, { "id": "SM01332", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin C-terminal", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 290, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1C1A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1A2" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 136, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 278, 378 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 365, "end_pos": 367 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1H5-1", "uniprot_ac": "E1C1H5", "uniprot_id": "E1C1H5_CHICK", "mass": { "chemical_mass": 30834.0, "monoisotopic_mass": 30834.0 }, "refseq": { "ac": "XP_420224", "name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420224" }, "gene_names": [ { "name": "PABIR2", "type": "recommended", "evidence": [ { "id": "E1C1H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1H5" } ] }, { "name": "PABIR2", "type": "synonym", "evidence": [ { "id": "XP_420224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420224" } ] } ], "protein_names": [ { "name": "P2R1A-PPP2R2A-interacting phosphatase regulator 1", "type": "synonym", "evidence": [ { "id": "XP_420224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420224" } ] }, { "name": "PABIR family member 2", "type": "synonym", "evidence": [ { "id": "E1C1H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1H5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_420224.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420224" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1H5", "url": "https://www.uniprot.org/uniprotkb/E1C1H5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PABIR2", "url": "https://www.uniprot.org/uniprotkb/E1C1H5", "locus": { "chromosome": "4", "start_pos": 4025160, "end_pos": 4035754, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014691", "url": "https://www.ensembl.org/id/ENSGALG00010014691" } ] } } ], "crossref": [ { "id": "E1C1H5", "url": "https://alphafold.ebi.ac.uk/entry/E1C1H5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006108", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006108", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "422236", "url": "https://www.ncbi.nlm.nih.gov/gene/422236", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422236", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422236", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDVDCPI", "url": "https://omabrowser.org/oma/group/MDVDCPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C1H5", "url": "https://www.orthodb.org/?gene=E1C1H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22227", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22227", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22227:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22227:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_420224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C1H5", "url": "https://www.uniprot.org/uniprotkb/E1C1H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1H5-1", "url": "https://www.uniprot.org/uniprotkb/E1C1H5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQEKMELDLELPPGSAAAPSDGGGLRRSNSAPLIHGLSDSSQVFQPYVLRTRRNSTTVTSRHSMLLSSSPIRIPSSRLHQIRREEGVDLMNRETAHEREVQTAMQISQSWEESLSLSDNDLDKSEKSSSPKRIDFIPVSPAPSPTRGIGKQCFSPSLQMFVSSNGLPPSPIPSPTRRFSNRRSQSPINCIRPSVLGPIKRKGEMETESQPKRLFQGTTNMLSPDVTHLTDLSSCLSSDILDGSSSSVGSSSDSLTKGSITTESPVTCSNSCSSFILMDDLSPK", "length": 284, "header": "tr|E1C1H5-1|E1C1H5_CHICK Isoform 1 of PABIR family member 2 OS=Gallus gallus OX=9031 GN=PABIR2 PE=3 SV=4 CANONICAL=E1C1H5-1" }, "isoforms": [ { "isoform_ac": "E1C1H5-1", "url": "https://www.uniprot.org/uniprotkb/E1C1H5/entry#E1C1H5-1", "sequence": { "sequence": "MAQEKMELDLELPPGSAAAPSDGGGLRRSNSAPLIHGLSDSSQVFQPYVLRTRRNSTTVTSRHSMLLSSSPIRIPSSRLHQIRREEGVDLMNRETAHEREVQTAMQISQSWEESLSLSDNDLDKSEKSSSPKRIDFIPVSPAPSPTRGIGKQCFSPSLQMFVSSNGLPPSPIPSPTRRFSNRRSQSPINCIRPSVLGPIKRKGEMETESQPKRLFQGTTNMLSPDVTHLTDLSSCLSSDILDGSSSSVGSSSDSLTKGSITTESPVTCSNSCSSFILMDDLSPK", "length": 284, "header": "tr|E1C1H5-1|E1C1H5_CHICK Isoform 1 of PABIR family member 2 OS=Gallus gallus OX=9031 GN=PABIR2 PE=3 SV=4 CANONICAL=E1C1H5-1" }, "locus": { "chromosome": "4", "start_pos": 4035623, "end_pos": 4027497, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010035269.1", "url": "https://www.ensembl.org/id/ENSGALT00010035269.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010020544.1", "url": "https://www.ensembl.org/id/ENSGALP00010020544.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 146, "start_aa": "Thr", "end_pos": 146, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr146", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:422236", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422236", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M803-1", "protein_name": "PABIR family member 2", "gene_name": "PABIR2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQEKMELDFEPDTSDGGTLRRSNSAPLIHGLSDLSQVFQPYTFRARRNSTTVMSRHNLEEGMDIMNRETAHEREVQTAMQISQSWDESLSLSDSDFDKQEKLYSPKRIDFTPVSPAPSPTRGFGKMFVSSSGLPPSPVPSPRRFSTRRSQSPIKCIRPSVLAPLKRKGEMETESQPKRLFQGTTNMLSPEAAQLSDLSSCSDILDGSNSGSGLSSESLAKGSTTADAPVACSNSCSPFILMEDLSPK", "length": 248 }, "evidence": [ { "id": "E1C1H5", "url": "https://omabrowser.org/oma/group/E1C1H5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2MII6-1", "protein_name": "Protein FAM122B isoform X1", "gene_name": "Fam122b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQEKMELDFEADTSDGGTLRRSNSAPLIHVLSDLSQVFEPYPLRTRRNSATIMSHHSLEEGLDMMNRETSLGREAQAGMQISQSWDESLSLSDSDFDKPEKLYSPKRIDFTPVSPAPSPTRGFGKQCYSPSLQMFVSSSGMPSSPVSNPRHFSSRRSQSPVKCIRPNALGPLKRKGEMETESQPKRLFQGTTTMLSTDAGQLSDLSSCSDILDGSSISSGLSSDSLATGSAPAESPVACSNSCSSFILMDDLSPK", "length": 256 }, "evidence": [ { "id": "E1C1H5", "url": "https://omabrowser.org/oma/group/E1C1H5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6NZE7-1", "protein_name": "PABIR family member 2", "gene_name": "Pabir2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQEKMDLDFEADTSEGATLRRSNSAPLIHVLSDLSQVFEPYPLRTGRTSTAIMSHHSLEEGLDMMNRETTNEREAQAGMQISQSWDESLSLSDSDFDKPEKLYSPKRIDFTPVSPAPSPTRGFGKQCLSPSLQMFVSSSGMPPSPVLNPRHFSRRSQSPVKCIRPSVLGPLKRKGEMEMESQPKRPFQGTTSMLSTNPAQLSDFSSCSDILDGSSISSGLSSDSLATGSAPAESPVACSNSCSPFILMDDLSPK", "length": 255 }, "evidence": [ { "id": "E1C1H5", "url": "https://omabrowser.org/oma/group/E1C1H5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "E1C1H5", "url": "https://www.uniprot.org/uniprotkb/E1C1H5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C1H5", "url": "https://www.uniprot.org/uniprotkb/E1C1H5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C1H5", "url": "https://www.uniprot.org/uniprotkb/E1C1H5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "E1C1H5", "url": "https://www.uniprot.org/uniprotkb/E1C1H5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1H5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 284, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1H5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1H5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 146 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1J3-1", "uniprot_ac": "E1C1J3", "uniprot_id": "E1C1J3_CHICK", "mass": { "chemical_mass": 19579.0, "monoisotopic_mass": 19579.0 }, "refseq": { "ac": "NP_001264443", "name": "zinc finger matrin-type protein 5 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264443" }, "gene_names": [ { "name": "ZMAT5", "type": "recommended", "evidence": [ { "id": "E1C1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1J3" } ] }, { "name": "ZMAT5", "type": "synonym", "evidence": [ { "id": "NP_001264443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264443" } ] } ], "protein_names": [ { "name": "Zinc finger matrin-type protein 5", "type": "recommended", "evidence": [ { "id": "E1C1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1J3/entry#names_and_taxonomy" } ] }, { "name": "U11/U12 small nuclear ribonucleoprotein 20 kDa protein", "type": "synonym", "evidence": [ { "id": "E1C1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1J3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger matrin-type protein 5 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001264443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264443" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX930880.2, BX933282.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX930880.2. Transcript Variant: This variant (2) uses an alternate 3' structure, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus, compared to isoform 1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264443" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1J3", "url": "https://www.uniprot.org/uniprotkb/E1C1J3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZMAT5", "url": "https://www.uniprot.org/uniprotkb/E1C1J3", "locus": { "chromosome": "15", "start_pos": 11052800, "end_pos": 11039942, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010000307", "url": "https://www.ensembl.org/id/ENSGALG00010000307" } ] } } ], "crossref": [ { "id": "E1C1J3", "url": "https://alphafold.ebi.ac.uk/entry/E1C1J3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008070", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008070", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417017", "url": "https://www.ncbi.nlm.nih.gov/gene/417017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417017", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417017", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPPIQEL", "url": "https://omabrowser.org/oma/group/WPPIQEL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PMH8", "url": "https://www.orthodb.org/?gene=A0A1D5PMH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1J3", "url": "https://www.orthodb.org/?gene=E1C1J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16465:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16465:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06220", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06220", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72165", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264443", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PMH8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1J3", "url": "https://www.uniprot.org/uniprotkb/E1C1J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1J3-1", "url": "https://www.uniprot.org/uniprotkb/E1C1J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGVQHLRAKRAWYDLFRDAAAILQEEQSKKPCRKFLQTGQCDFGSNCRFSHMTEQDLEKLSAQVQGEQRLRELRQEGAEIPPGTIENWLEKRAKRLSVAQSNSALPEKPTPFQYPPGWPPLQELPPSLRAPPPGGWPVPPGLQWG", "length": 170, "header": "tr|E1C1J3-1|E1C1J3_CHICK Isoform 1 of Zinc finger matrin-type protein 5 OS=Gallus gallus OX=9031 GN=ZMAT5 PE=4 SV=1 CANONICAL=E1C1J3-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PMH8-1", "url": "https://www.uniprot.org/uniprotkb/E1C1J3/entry#A0A1D5PMH8-1", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGVQHLRAKRAWYDLFRDAAAILQEEQSKKPCRKFLQTGQCDFGSNCRFSHMTEQDLEKLSAQVQVRKTALVQVLELLMKSQGSSRKPRAPVPTVLEHLQ", "length": 125, "header": "tr|A0A1D5PMH8-1|A0A1D5PMH8_CHICK Computationally mapped isoform of Zinc finger matrin-type protein 5 OS=Gallus gallus OX=9031 GN=ZMAT5 PE=4 SV=1 CANONICAL=E1C1J3-1" }, "locus": { "chromosome": "15", "start_pos": 11052530, "end_pos": 11041868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000580.1", "url": "https://www.ensembl.org/id/ENSGALT00010000580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000338.1", "url": "https://www.ensembl.org/id/ENSGALP00010000338.1" } ] } }, { "isoform_ac": "E1C1J3-1", "url": "https://www.uniprot.org/uniprotkb/E1C1J3/entry#E1C1J3-1", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGVQHLRAKRAWYDLFRDAAAILQEEQSKKPCRKFLQTGQCDFGSNCRFSHMTEQDLEKLSAQVQGEQRLRELRQEGAEIPPGTIENWLEKRAKRLSVAQSNSALPEKPTPFQYPPGWPPLQELPPSLRAPPPGGWPVPPGLQWG", "length": 170, "header": "tr|E1C1J3-1|E1C1J3_CHICK Isoform 1 of Zinc finger matrin-type protein 5 OS=Gallus gallus OX=9031 GN=ZMAT5 PE=4 SV=1 CANONICAL=E1C1J3-1" }, "locus": { "chromosome": "15", "start_pos": 11050205, "end_pos": 11041868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010000578.1", "url": "https://www.ensembl.org/id/ENSGALT00010000578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010000336.1", "url": "https://www.ensembl.org/id/ENSGALP00010000336.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417017", "resource": "KEGG Pathway" }, { "id": "R-GGA-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZLD2-1", "protein_name": "Zinc finger matrin-type protein 5", "gene_name": "Zmat5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSEQDLQGLSVQVEVRRKTRKLRLITLPRVRDLAGATPCYHPHCLLHPQFEPLLRVKLCGHRPASSSPRLGDMPLFFKERRAREWPLETAELPEGHLEDWLEKRAKRLSSAPSSRAEPIRTTVFQYPVGWPPMQELPPSLRAPPPGGWSVQSRVQWG", "length": 233 }, "evidence": [ { "id": "E1C1J3", "url": "https://omabrowser.org/oma/group/E1C1J3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RFG8-1", "protein_name": "Zinc finger matrin-type protein 5", "gene_name": "ZMAT5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKLWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSIQVEEERRAREWPLEVAELPEGHLEDWLEKRAKRLSSASSSRAEPIRATVFQYPLGWPPVQELPLSLRAPPPGGWPLQPSIQWG", "length": 170 }, "evidence": [ { "id": "E1C1J3", "url": "https://omabrowser.org/oma/group/E1C1J3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HP14-1", "protein_name": "Zinc finger matrin-type protein 5", "gene_name": "Zmat5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSIQVEEERRAREWPLETAELPEGHLEDWLEKRAKRLSSVPSSRTEPIRTTVFQYPVGWPPMQELPPSLRAPPPGGWSLQPRVQWG", "length": 170 }, "evidence": [ { "id": "E1C1J3", "url": "https://omabrowser.org/oma/group/E1C1J3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2TA39-1", "protein_name": "Zinc finger matrin-type protein 5", "gene_name": "ZMAT5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKLWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSVQVEEERRAREWPLDVAELPEVCLEDWLEKRAKRLSSAPSSRAEPVRATVFQYPVGWPPVQELPPSLRAPPPGGWPLQPSVQWG", "length": 170 }, "evidence": [ { "id": "E1C1J3", "url": "https://omabrowser.org/oma/group/E1C1J3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CQR5-1", "protein_name": "Zinc finger matrin-type protein 5", "gene_name": "Zmat5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSEQDLQELSVQVEEERRAREWPLETAELPEGHLEDWLEKRAKRLSSAPSSRAEPIRTTVFQYPVGWPPMQELPPSLRAPPPGGWSVLSKVQWG", "length": 170 }, "evidence": [ { "id": "E1C1J3", "url": "https://omabrowser.org/oma/group/E1C1J3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UDW3-1", "protein_name": "Zinc finger matrin-type protein 5", "gene_name": "ZMAT5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSIQVEEERRAREWLLDAPELPEGHLEDWLEKRAKRLSSAPSSRAEPIRTTVFQYPVGWPPVQELPPSLRAPPPGGWPLQPRVQWG", "length": 170 }, "evidence": [ { "id": "E1C1J3", "url": "https://omabrowser.org/oma/group/E1C1J3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E1C1J3", "url": "https://www.uniprot.org/uniprotkb/E1C1J3" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "E1C1J3", "url": "https://www.uniprot.org/uniprotkb/E1C1J3" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "E1C1J3", "url": "https://www.uniprot.org/uniprotkb/E1C1J3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E1C1J3", "url": "https://www.uniprot.org/uniprotkb/E1C1J3" } ], "pmid": "" }, { "name": "RNA 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"https://alphafold.ebi.ac.uk/entry/E1C1J3" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C1J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1J3" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 79, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1K8-1", "uniprot_ac": "E1C1K8", "uniprot_id": "E1C1K8_CHICK", "mass": { "chemical_mass": 48422.0, "monoisotopic_mass": 48422.0 }, "refseq": { "ac": "XP_004946840", "name": "oligodendrocyte-myelin glycoprotein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946840" }, "gene_names": [ { "name": "OMG", "type": "recommended", "evidence": [ { "id": "E1C1K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1K8" } ] }, { "name": "OMG", "type": "synonym", "evidence": [ { "id": "XP_004946840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946840" } ] } ], "protein_names": [ { "name": "Oligodendrocyte-myelin glycoprotein", "type": "recommended", "evidence": [ { "id": "E1C1K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1K8/entry#names_and_taxonomy" } ] }, { "name": "oligodendrocyte-myelin glycoprotein", "type": "synonym", "evidence": [ { "id": "XP_004946840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946840" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052550.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004946840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946840" } ] }, { "annotation": "Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.", "evidence": [ { "database": "UniProtKB", "id": "E1C1K8", "url": "https://www.uniprot.org/uniprotkb/E1C1K8#function" }, { "database": "UniProtKB", "id": "ARBA00055448", "url": "https://www.uniprot.org/uniprotkb/ARBA00055448#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1K8", "url": "https://www.uniprot.org/uniprotkb/E1C1K8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OMG", "url": "https://www.uniprot.org/uniprotkb/E1C1K8", "locus": { "chromosome": "19", "start_pos": 9530876, "end_pos": 9515452, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029545", "url": "https://www.ensembl.org/id/ENSGALG00010029545" } ] } } ], "crossref": [ { "id": "ENSGALG00000005594", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101751011", "url": "https://www.ncbi.nlm.nih.gov/gene/101751011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101751011", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDKAFDQ", "url": "https://omabrowser.org/oma/group/PDKAFDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C1K8", "url": "https://www.orthodb.org/?gene=E1C1K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47114:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47114:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193634", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004946840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004946840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C1K8", "url": "https://www.uniprot.org/uniprotkb/E1C1K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1K8-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHQILKTSTCLLVLLFFIPTVLGICPSNCTCSGNNRNVDCSGRNLTVLPHGLQDNITYLNLSFNQFVDLDHQLTRFSNLRTLDISNNWLKNVPAHLPKSLWELYAINNNIKVLQKLDTAYQWNLKVLDVSRNMVERAVLINNTLSSLKFLNLSSNKLWTVPTNMPYNIETVDLSNNFLSQILPGTLVRLQHLTSLYLHNNKFTYIPDKAFDQLFQLQVVTLYNNPWSCSNEQNISYLLKWVHSTTARVRGAPCADQSMLWANVTPTSATAPDASFMIKGMKAADTPAAAEPTQMTKMHKQFKAKEITTLASLSQTVLFTSTDRPLLLYPEELTTRKVSAYEAAATHTIYIKDTTEVNSSLTHSTGSSTTPMTLSITSGMPTNYSRMPQSTTATLRREEATTSVLNTDVPSKASICAICLFYAVMLNAVAAFIG", "length": 434, "header": "tr|E1C1K8-1|E1C1K8_CHICK Isoform 1 of Oligodendrocyte-myelin glycoprotein OS=Gallus gallus OX=9031 GN=OMG PE=4 SV=1 CANONICAL=E1C1K8-1" }, "isoforms": [ { "isoform_ac": "E1C1K8-1", "url": "https://www.uniprot.org/uniprotkb/E1C1K8/entry#E1C1K8-1", "sequence": { "sequence": "MEHQILKTSTCLLVLLFFIPTVLGICPSNCTCSGNNRNVDCSGRNLTVLPHGLQDNITYLNLSFNQFVDLDHQLTRFSNLRTLDISNNWLKNVPAHLPKSLWELYAINNNIKVLQKLDTAYQWNLKVLDVSRNMVERAVLINNTLSSLKFLNLSSNKLWTVPTNMPYNIETVDLSNNFLSQILPGTLVRLQHLTSLYLHNNKFTYIPDKAFDQLFQLQVVTLYNNPWSCSNEQNISYLLKWVHSTTARVRGAPCADQSMLWANVTPTSATAPDASFMIKGMKAADTPAAAEPTQMTKMHKQFKAKEITTLASLSQTVLFTSTDRPLLLYPEELTTRKVSAYEAAATHTIYIKDTTEVNSSLTHSTGSSTTPMTLSITSGMPTNYSRMPQSTTATLRREEATTSVLNTDVPSKASICAICLFYAVMLNAVAAFIG", "length": 434, "header": "tr|E1C1K8-1|E1C1K8_CHICK Isoform 1 of Oligodendrocyte-myelin glycoprotein OS=Gallus gallus OX=9031 GN=OMG PE=4 SV=1 CANONICAL=E1C1K8-1" }, "locus": { "chromosome": "19", "start_pos": 9522035, "end_pos": 9520734, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071417.1", "url": "https://www.ensembl.org/id/ENSGALT00010071417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010044107.1", "url": "https://www.ensembl.org/id/ENSGALP00010044107.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 267, "start_aa": "Thr", "end_pos": 267, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr267", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101751011", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751011", "resource": "KEGG Pathway" }, { "id": "R-GGA-193634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193634", "resource": "Reactome", "description": "Axonal growth inhibition (RHOA activation)" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJ55-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "OMG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALMEYQILKMSPSLFILLLLTPGILCICPLQCICTERHRHVDCSGRNLTTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLEKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSHNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQAFDQLLQLQEITLYNNRWSCDHQQNITYLLKWMMETKAHVIGTPCSSQISSLKEHSIYPTPPGFTSSLFTLSGIQTVDTINSLSMVTQSKVTKIPKQYRTKETFGATLSKDTTFTSTDKAFVPYPEDTSTEMINSHEAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLRREETTTNVKTRSPSSVANAWKVNALFLLMLNAVVMLAV", "length": 443 }, "evidence": [ { "id": "E1C1K8", "url": "https://omabrowser.org/oma/group/E1C1K8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6Q889-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "OMG", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALMEYQILKMSPSLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLTTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLEKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHTVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQAFDQLFQLQEITLYNNRWSCDHHQNITYLLKWMMETKAHVIGTPCSSQISSLKEHSIYPTPSGFTSSLFTVSGMQTVDTINSLSTVTQSKVTKIPKQYRTKETTFGATLSKDTTLTSTDKAFVPYPEDTSTETINSREAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNDFSEMPQQSTTLNLRREETTTDGKTRLPSVASAWKVNASFLLMLNAVVMLAV", "length": 443 }, "evidence": [ { "id": "E1C1K8", "url": "https://omabrowser.org/oma/group/E1C1K8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7EYB9-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "Omg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALMEYQILKMSSCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLLQLQEITLHNNRWSCDHTQNITYLLKWMMETKAHVIGIPCSKQVSSLKEQSMYPTPPGFTSSLFTMSEMQTVDTINSLSMVTQPKVTNIPKQYRGKDTTFGVTLSKDTTFSSTDRALEPYPEDTPTEMTSSREAAAATLTIHLQDGMSSNASLTSAAKSSPAPVTLSITSGMPNNFSEMPQQSTTLNLRREETTANVKTQPPSSASAWKVNASLLLMLNAVVMLAG", "length": 443 }, "evidence": [ { "id": "E1C1K8", "url": "https://omabrowser.org/oma/group/E1C1K8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23515-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "OMG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKVTKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVANAWKVNASFLLLLNVVVMLAV", "length": 440 }, "evidence": [ { "id": "E1C1K8", "url": "https://omabrowser.org/oma/group/E1C1K8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63912-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "Omg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEYQILKMSSCLFILLFLTPGILCICPLQCTCTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPEQSFDQLLQLQEITLHNNRWSCDHKQNITYLLKWVMETKAHVIGTPCSKQVSSLKEQSMYPTPPGFTSSLFTMSEMQTVDTINSLSMVTQPKVTKTPKQYRGKETTFGVTLSKDTTFSSTDRAVVAYPEDTPTEMTNSHEAAAATLTIHLQDGMSSNASLTSATKSPPSPVTLSIARGMPNNFSEMPRQSTTLNLRREETTANGNTRPPSAASAWKVNASLLLMLNAVVMLAG", "length": 440 }, "evidence": [ { "id": "E1C1K8", "url": "https://omabrowser.org/oma/group/E1C1K8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C1K8", "url": "https://www.uniprot.org/uniprotkb/E1C1K8" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "E1C1K8", "url": "https://www.uniprot.org/uniprotkb/E1C1K8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "E1C1K8", "url": "https://www.uniprot.org/uniprotkb/E1C1K8" } ], "pmid": "" }, { "name": "neuron projection regeneration", "id": "GO:0031102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031102", "evidence": [ { "database": "UniProtKB", "id": "E1C1K8", "url": "https://www.uniprot.org/uniprotkb/E1C1K8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C1K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1K8" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 59, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 267 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1Q8-1", "uniprot_ac": "E1C1Q8", "uniprot_id": "E1C1Q8_CHICK", "mass": { "chemical_mass": 56747.0, "monoisotopic_mass": 56747.0 }, "refseq": { "ac": "XP_004937125", "name": "monocarboxylate transporter 14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937125" }, "gene_names": [ { "name": "SLC16A14", "type": "recommended", "evidence": [ { "id": "E1C1Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8" } ] }, { "name": "SLC16A14", "type": "synonym", "evidence": [ { "id": "XP_004937125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937125" } ] } ], "protein_names": [ { "name": "Solute carrier family 16 member 14", "type": "synonym", "evidence": [ { "id": "E1C1Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8/entry#names_and_taxonomy" } ] }, { "name": "monocarboxylate transporter 14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004937125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937125" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004937125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937125" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1Q8", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC16A14", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8", "locus": { "chromosome": "9", "start_pos": 9806883, "end_pos": 9820905, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023290", "url": "https://www.ensembl.org/id/ENSGALG00010023290" } ] } } ], "crossref": [ { "id": "E1C1Q8", "url": "https://alphafold.ebi.ac.uk/entry/E1C1Q8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002897", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002897", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424784", "url": "https://www.ncbi.nlm.nih.gov/gene/424784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424784", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424784", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVFISCC", "url": "https://omabrowser.org/oma/group/CVFISCC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C1Q8", "url": "https://www.orthodb.org/?gene=E1C1Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004937125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004937125", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C1Q8", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1Q8-1", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYASREDIGYDFGDDSKVGSKPIKPNPNIDGGWAWMIVFSSFLVHILIMGSQMALGILNMEWLEEFNQSRGLTAWVSSLSMGITLIVGPFIGLFITMCGCRKTAIIGGILNALGWILSAYASNVHYLFLTFGVTAGIGSGMVYLPAVVMVGQYFHKRRALAQGLSTTGTGFGAFLMTALLKYLCREFGWRNAMFIQGAICLNLCVCGALMRPLSPKVLNEKYVVRSNSEDNQAKALSHSAETIKSNGVLSEEPEKKEVIKNEEVLDDIKHIEIGGKSRIGKSMYGLRILKTVSQQTVTVRKGFGIWYSSYFGAASLFTNRVFVAFIIWALFAYSSFVIPFIHLPEIVKQYSLSSQNNVFPLTSIIAIVHIFGKVILGIISDLPCISTWNVFLMANFTLVTCILTLPLMQTYISLAVVCALIGFSSGYFSLMPVVTEDLVGTKHLANAYGIIICANGISALLGPPFAGWIYDITHKYDFSFYICGSLYLVGILFLFMQPYIGKKQSQEKSTEEAQV", "length": 515, "header": "tr|E1C1Q8-1|E1C1Q8_CHICK Isoform 1 of Solute carrier family 16 member 14 OS=Gallus gallus OX=9031 GN=SLC16A14 PE=4 SV=4 CANONICAL=E1C1Q8-1" }, "isoforms": [ { "isoform_ac": "E1C1Q8-1", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8/entry#E1C1Q8-1", "sequence": { "sequence": "MYASREDIGYDFGDDSKVGSKPIKPNPNIDGGWAWMIVFSSFLVHILIMGSQMALGILNMEWLEEFNQSRGLTAWVSSLSMGITLIVGPFIGLFITMCGCRKTAIIGGILNALGWILSAYASNVHYLFLTFGVTAGIGSGMVYLPAVVMVGQYFHKRRALAQGLSTTGTGFGAFLMTALLKYLCREFGWRNAMFIQGAICLNLCVCGALMRPLSPKVLNEKYVVRSNSEDNQAKALSHSAETIKSNGVLSEEPEKKEVIKNEEVLDDIKHIEIGGKSRIGKSMYGLRILKTVSQQTVTVRKGFGIWYSSYFGAASLFTNRVFVAFIIWALFAYSSFVIPFIHLPEIVKQYSLSSQNNVFPLTSIIAIVHIFGKVILGIISDLPCISTWNVFLMANFTLVTCILTLPLMQTYISLAVVCALIGFSSGYFSLMPVVTEDLVGTKHLANAYGIIICANGISALLGPPFAGWIYDITHKYDFSFYICGSLYLVGILFLFMQPYIGKKQSQEKSTEEAQV", "length": 515, "header": "tr|E1C1Q8-1|E1C1Q8_CHICK Isoform 1 of Solute carrier family 16 member 14 OS=Gallus gallus OX=9031 GN=SLC16A14 PE=4 SV=4 CANONICAL=E1C1Q8-1" }, "locus": { "chromosome": "9", "start_pos": 9816757, "end_pos": 9809238, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056791.1", "url": "https://www.ensembl.org/id/ENSGALT00010056791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034527.1", "url": "https://www.ensembl.org/id/ENSGALP00010034527.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424784", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424784", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GSK8-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYTSHEDIGYVLDDDPKAKKPLKPHPDIDGGWAWVMVLSSFFVHMLIMGSQMALGVLNVEWLEEFQQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAPNVQTLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTLLLKYLCAEYGWRKAMFIQGAVSLNLCVCGALMRPLSPGKVENCPREEKPCALPAYSTESVKSGPLGLTEEQDRQPGNEETVCDLQAQECQGQTHPRKNMCAFRVLKTVSQLTVRVRKGFGDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYGLSEQNDMFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVFSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMVEQSRRKYTDGAHV", "length": 509 }, "evidence": [ { "id": "E1C1Q8", "url": "https://omabrowser.org/oma/group/E1C1Q8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9TYA2-1", "protein_name": "Solute carrier family 16 member 14", "gene_name": "SLC16A14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYTSHEDIGYDFEDDPKDKKTLKPHPDIDGGWAWVMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGVTLIVGPFIGLFINTCGCRRTAIIGGLLNSLGWVLSAYAVNVYYLFITFGLAAGFGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGAVSLNLCVCGALMRPLSPGMDGDGPEGKAPHHVLPAHSTESIRSSGQLRDAEEKRGGPGTEDSSLGDAPAQACQEKAAHRKDMCAFRLLKTVSQLTMRVRKGFWDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVVLGIVADLPCISVWNVFLMANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYISGLLYMSFPASGFFPVNWLFTSGGQSIGASASASALPINVQG", "length": 520 }, "evidence": [ { "id": "E1C1Q8", "url": "https://omabrowser.org/oma/group/E1C1Q8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A0E5-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKVENCSGAEEPCALPAYSTESVKSGGPLDMTEEQDRRPGNEETVCDLQTQELQGQTHPRKNVCAFRVLKTVGQLTVRVQRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDAFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMTEQSGRKCMDSAHV", "length": 512 }, "evidence": [ { "id": "E1C1Q8", "url": "https://omabrowser.org/oma/group/E1C1Q8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SMZ2-1", "protein_name": "Solute carrier family 16 member 14", "gene_name": "SLC16A14", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYTSHEDIGYDFEDDPKEKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGVTLIVGPFIGLFINTCGCRRTAIIGGLLNSLGWVLSAYAANVHYLFITFGLAAGFGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGAVSLNLCVCGALMRPLSPGMDGDVPGGKEPHVIPAHSTESIRSSGQPGGTEEKEGGPGTDDSLGDVPVPEKAAHRKDMCAFRVLKMMSQLTVKIRKGFQDWYSGYFGTASLFTNRMFVAFVFWALFAYSSFVIPFIHLPEIVNLYNLSEENDVFPLTSIIAIVHIFGKVILGIVADLPCISVWNVFLMANFTLVLCIFILPSMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYVCGLLYMVGILFLLIQPCIHIIEQSRKKYMDGANA", "length": 507 }, "evidence": [ { "id": "E1C1Q8", "url": "https://omabrowser.org/oma/group/E1C1Q8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7RTX9-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "SLC16A14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYTSHEDIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPCIRIIEQSRRKYMDGAHV", "length": 510 }, "evidence": [ { "id": "E1C1Q8", "url": "https://omabrowser.org/oma/group/E1C1Q8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1C7-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKLENCPEAEEPCALPAYSTESVKSGGPLGMAEEQDRRPGNEEMVCDLQTQECQGQTHPRKNVCAFRVLKTVSQLTVQVRRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMIDQSRRKCIEGAHV", "length": 512 }, "evidence": [ { "id": "E1C1Q8", "url": "https://omabrowser.org/oma/group/E1C1Q8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C1Q8", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "E1C1Q8", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carboxylic acid transmembrane transport", "id": "GO:1905039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905039", "evidence": [ { "database": "UniProtKB", "id": "E1C1Q8", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1Q8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 515, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1Q8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1Q8" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C1Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1Q8" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 502, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 395, "end_pos": 397 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C1U2-1", "uniprot_ac": "E1C1U2", "uniprot_id": "E1C1U2_CHICK", "mass": { "chemical_mass": 22569.0, "monoisotopic_mass": 22569.0 }, "refseq": { "ac": "NP_001186543", "name": "interleukin-22 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" }, "gene_names": [ { "name": "IL22", "type": "recommended", "evidence": [ { "id": "E1C1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1U2" } ] }, { "name": "IL-22", "type": "synonym", "evidence": [ { "id": "NP_001186543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" } ] }, { "name": "IL22", "type": "synonym", "evidence": [ { "id": "NP_001186543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" } ] }, { "name": "interleukin-22", "type": "synonym", "evidence": [ { "id": "NP_001186543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" } ] } ], "protein_names": [ { "name": "Interleukin 22", "type": "synonym", "evidence": [ { "id": "E1C1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1U2/entry#names_and_taxonomy" } ] }, { "name": "interleukin-22 precursor", "type": "synonym", "evidence": [ { "id": "NP_001186543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ617782.1, CF256793.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF256793.1 and JAENSK010000012.1. On Dec 11, 2010 this sequence version replaced XP_416079.1. Sequence Note: This RefSeq record was created from transcripts and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001186543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" } ] }, { "annotation": "Cloning and expression of ChIL-22 and ChIL22BP; data indicate IL-22 is a member of the IL-10 family and induces pro-inflammatory cytokines and antimicrobial peptides in epithelial cells and hepatocytes, but not in immune type cells", "evidence": [ { "database": "RefSeq", "id": "NP_001186543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" }, { "database": "PubMed", "id": "22980486", "url": "https://glygen.org/publication/PubMed/22980486" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1U2", "url": "https://www.uniprot.org/uniprotkb/E1C1U2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IL22", "url": "https://www.uniprot.org/uniprotkb/E1C1U2", "locus": { "chromosome": "1", "start_pos": 35228884, "end_pos": 35231341, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012472", "url": "https://www.ensembl.org/id/ENSGALG00010012472" } ] } } ], "crossref": [ { "id": "E1C1U2", "url": "https://alphafold.ebi.ac.uk/entry/E1C1U2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009904", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "417838", "url": "https://www.ncbi.nlm.nih.gov/gene/417838", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417838", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417838", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "INFQQPY", "url": "https://omabrowser.org/oma/group/INFQQPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C1U2", "url": "https://www.orthodb.org/?gene=E1C1U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48488:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48488:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1C1U2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1C1U2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-8854691", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854691", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C1U2", "url": "https://www.uniprot.org/uniprotkb/E1C1U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1U2-1", "url": "https://www.uniprot.org/uniprotkb/E1C1U2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLHTLTRSFSGWVVFCCCCCFPLLLTSPLPPKGTGVVSNAHQACRLRKINFQQPYIRNRTYTLAEMARLSDQDTDNRLIGQQIYVNIRENNRCYMMKRITEIIVKDVLLTEAKERYPYAEDVAQFLASLTSELSRCKYSGNREHIEKNLEEMKSKMKELGENGKNKAIGELDLLFDYIENACTDAPKKGGNKKKN", "length": 197, "header": "tr|E1C1U2-1|E1C1U2_CHICK Isoform 1 of Interleukin 22 OS=Gallus gallus OX=9031 GN=IL22 PE=4 SV=1 CANONICAL=E1C1U2-1" }, "isoforms": [ { "isoform_ac": "E1C1U2-1", "url": "https://www.uniprot.org/uniprotkb/E1C1U2/entry#E1C1U2-1", "sequence": { "sequence": "MATLHTLTRSFSGWVVFCCCCCFPLLLTSPLPPKGTGVVSNAHQACRLRKINFQQPYIRNRTYTLAEMARLSDQDTDNRLIGQQIYVNIRENNRCYMMKRITEIIVKDVLLTEAKERYPYAEDVAQFLASLTSELSRCKYSGNREHIEKNLEEMKSKMKELGENGKNKAIGELDLLFDYIENACTDAPKKGGNKKKN", "length": 197, "header": "tr|E1C1U2-1|E1C1U2_CHICK Isoform 1 of Interleukin 22 OS=Gallus gallus OX=9031 GN=IL22 PE=4 SV=1 CANONICAL=E1C1U2-1" }, "locus": { "chromosome": "1", "start_pos": 35231194, "end_pos": 35229119, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010029910.1", "url": "https://www.ensembl.org/id/ENSGALT00010029910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010017411.1", "url": "https://www.ensembl.org/id/ENSGALP00010017411.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Molecular characterization and immunological roles of avian IL-22 and its soluble receptor IL-22 binding protein.", "journal": "Cytokine", "date": "2012-12", "authors": "Kim Sungwon, Faris Laura, Cox Chasity M, Sumners Lindsay H, Jenkins Mark C, Fetterer Ray H, Miska Kate B, Dalloul Rami A", "evidence": [ { "database": "RefSeq", "id": "NP_001186543", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186543" } ], "reference": [ { "type": "PubMed", "id": "22980486", "url": "https://glygen.org/publication/PubMed/22980486" } ] } ], "pathway": [ { "id": "gga:417838", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417838", "resource": "KEGG Pathway" }, { "id": "R-GGA-8854691", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854691", "resource": "Reactome", "description": "Interleukin-20 family signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MQU8-1", "protein_name": "Interleukin-22", "gene_name": "Il22", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVLQKKSMSFSFMGLLAASCLLLIALWAQEAVGLPISSHCKLDVSDFQRPYFTNRTFRLAEEASLADNNTDVRLIGDELFQGVNRNNRCYLMKQVLNFTLAEVLIPQSDRFQPYMQQVVPFLTKLSNQLSLCQISGNGQRIQKNVQTLKETVKQLGESGEIKAIGELNLLFMHLRNYCV", "length": 180 }, "evidence": [ { "id": "E1C1U2", "url": "https://omabrowser.org/oma/group/E1C1U2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A5JS75-1", "protein_name": "Interleukin 22", "gene_name": "IL22", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALQKSVGSPLRDTLAAGCLLVMVLCAQRGAAAPITSHCRLNESDFQEPYIFNHTFTLAQKASLADNITDVRLIGNKLFHGIHQVTKRCYVLKQVLNFILEEVLFPQSDKFHPYMEKVVPFFSRLSKKLSQCHVESDNQHIQRNVQNLKNTVKKLGESGEIKVIGELNLLFTTLKRECAQVDQGWKMGY", "length": 190 }, "evidence": [ { "id": "E1C1U2", "url": "https://omabrowser.org/oma/group/E1C1U2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SH68-1", "protein_name": "Interleukin 22", "gene_name": "IL22", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAALRTSGSPFLLETLAASCLLLLALWAQGGVAVPITHHCKLDQSNFQQPYITNRTFTLAQEASLADNNTDVRLIGNNLFQGVNQMRERCYLVKQVLNFTLEEVLFPNSDRFHPYMQEVASFLDSLSKKLSQCRIKGDDQHIQRNVNNFKDTVKKLGESGEIKVIGELYLLFMALKNECTLPGHSWKMDN", "length": 190 }, "evidence": [ { "id": "E1C1U2", "url": "https://omabrowser.org/oma/group/E1C1U2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V6X6-1", "protein_name": "Interleukin 22", "gene_name": "Il22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVLRKSMSFSLMGTLAASCLLLVALWAQKADALPINSQCKLEAANFQQPYIVNRTFMLAKEASLADNNTDVRLIGEELFRGVKAKDQCYLMKQVLNFTLEDVLLPQSDRFQPYMQEVVPFLTKLSSHLSPCHISGDDQNIQKNVRQLKETVQKLGESGEIKAIGELDLLFMSLRNACV", "length": 179 }, "evidence": [ { "id": "E1C1U2", "url": "https://omabrowser.org/oma/group/E1C1U2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9GZX6-1", "protein_name": "Interleukin-22", "gene_name": "IL22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALQKSVSSFLMGTLATSCLLLLALLVQGGAAAPISSHCRLDKSNFQQPYITNRTFMLAKEASLADNNTDVRLIGEKLFHGVSMSERCYLMKQVLNFTLEEVLFPQSDRFQPYMQEVVPFLARLSNRLSTCHIEGDDLHIQRNVQKLKDTVKKLGESGEIKAIGELDLLFMSLRNACI", "length": 179 }, "evidence": [ { "id": "E1C1U2", "url": "https://omabrowser.org/oma/group/E1C1U2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJY9-1", "protein_name": "Interleukin-22", "gene_name": "Il22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVLQKSMSFSLMGTLAASCLLLIALWAQEANALPVNTRCKLEVSNFQQPYIVNRTFMLAKEASLADNNTDVRLIGEKLFRGVSAKDQCYLMKQVLNFTLEDVLLPQSDRFQPYMQEVVPFLTKLSNQLSSCHISGDDQNIQKNVRRLKETVKKLGESGEIKAIGELDLLFMSLRNACV", "length": 179 }, "evidence": [ { "id": "E1C1U2", "url": "https://omabrowser.org/oma/group/E1C1U2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1C1U2", "url": "https://www.uniprot.org/uniprotkb/E1C1U2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "E1C1U2", "url": "https://www.uniprot.org/uniprotkb/E1C1U2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "E1C1U2", "url": "https://www.uniprot.org/uniprotkb/E1C1U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1U2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 197, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1U2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1U2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1C1V6-1", "uniprot_ac": "E1C1V6", "uniprot_id": "E1C1V6_CHICK", "mass": { "chemical_mass": 80200.0, "monoisotopic_mass": 80200.0 }, "refseq": { "ac": "XP_004945276", "name": "uncharacterized protein LOC416530 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945276" }, "gene_names": [ { "name": "LOC416530", "type": "recommended", "evidence": [ { "id": "E1C1V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1V6" } ] }, { "name": "LOC416530", "type": "synonym", "evidence": [ { "id": "XP_004945276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945276" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "E1C1V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C1V6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC416530 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004945276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945276" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945276" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C1V6", "url": "https://www.uniprot.org/uniprotkb/E1C1V6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC416530", "url": "https://www.uniprot.org/uniprotkb/E1C1V6", "locus": {} } ], "crossref": [ { "id": "E1C1V6", "url": "https://alphafold.ebi.ac.uk/entry/E1C1V6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005291", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005291", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416530", "url": "https://www.ncbi.nlm.nih.gov/gene/416530", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR053234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416530", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416530", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWAFQWL", "url": "https://omabrowser.org/oma/group/LWAFQWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z674", "url": "https://www.orthodb.org/?gene=A0A8V0Z674", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C1V6", "url": "https://www.orthodb.org/?gene=E1C1V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33443:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33443:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945276", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z674", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z674", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z674-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z674-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1V6", "url": "https://www.uniprot.org/uniprotkb/E1C1V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C1V6-1", "url": "https://www.uniprot.org/uniprotkb/E1C1V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPSEEERERDVILISDDEDDGTLGNSVLIVDPLAKTALEEKKCEEVVDEECELMVTFCKQANVMPHARYDCTIHSFERMECETCSPIGKNADFCNQCYCYICDKLASECQIWTTSSLCHCNAHNKSKFWKDQRDFALAGVLVMFNLELTDIDADLRHGGNLLVSFIQELSVEYNKYLIGERIASTEHECFCVSKLPPGQCDTCRSRSTEIVYKYSGVFALVTRFLNQAEGESPKAAAVMLLGAAREITLHKDPALSWQNLGHTASLKLAVPCLLQRITTRLQKMLVLCDFPKSLYEKFINFFQSISLPCHCFAFSNSLNVVPWDHVLLTTVLKGQNTTGQRTQKGRKMFLWEVLPVIEARVEKLVENMNYKEVVRYLRAVKCNDTKGLRDLRDKIPFYLCKTGDFLDATHSLLFPINSLACCTACRLTPLQFEVYLKMFRTGSVPLGKDIQDPGPWVTVGSPMKDGVLIKQAFKLLYSNLSLYRNPKCWGSFIMIMGSSCFLGRNGHLRPLTVKEPPIAFQQGVLVASDGLFQELKAKINVSFPPGIFSQLHQEACLILAVQAVQQMVICELPYLTSFLEIFLAFGNNFWALRLLLNHLSYDECILRGIVNLVLRDLNRQKATMLKLWQNLGPQYVGEFICLFLTCRNRILQSIGVLALDIITENLHVCPWAKHLCNFFHNAGLMHLPLGATTHHEVSKFMDILEKL", "length": 708, "header": "tr|E1C1V6-1|E1C1V6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC416530 PE=4 SV=3 CANONICAL=E1C1V6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z674-1", "url": "https://www.uniprot.org/uniprotkb/E1C1V6/entry#A0A8V0Z674-1", "sequence": { "sequence": "MGPSEEERERDVILISDDEDDGTLGNSVLIVDPLAKTALEEKKCEEVVDEECELMVTFCKQANVMPHARYDCTIHSFERMECETCSPIGKNADFCNQCYCYICDKLASECQIWTTSSLCHCNAHNKSKFWKDQRDFALAGVLVMFNLELTDIDADLRHGGNLLVSFIQELSVEYNKYLIGERIASTEHECFCVSKLPPGQCDTCRSRSTEIVYKYSGVFALVTRFLNQAEGESPKAAAVMLLGAAREITLHKDPALSWQNLGHTASLKLAVPCLLQRITTRLQKMLVLCDFPKSLYEKFINFFQSISLPCHCFAFSNSLNVVPWDHVLLTTVLKGQNTTGQRTQKGRKMFLWEVLPVIEARVEKLVENMNYKEVVRYLRAVKCNDTKGLRDLRDKIPFYLCKTGDFLDATHSLLFPINSLACCTACRLTPLQFEVYLKMFRTGSVPLGKDIQDPGPWVTVGSPMKDGVLIKQAFKLLYSNLSLYRNPKCWGSFIMIMGSSCFLGRNGHLRPLTVKEPPIAFQQLHQEACLILAVQAVQQMVICELPYLTSFLEIFLAFGNNFWALRLLLNHLSYDECILRGIVNLVLRDLNRQKATMLKLWQNLGPQYVGEFICLFLTCRNRILQSIGVLALDIITENLHVG", "length": 642, "header": "tr|A0A8V0Z674-1|A0A8V0Z674_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC416530 PE=4 SV=1 CANONICAL=E1C1V6-1" }, "locus": { "chromosome": "14", "start_pos": 5977591, "end_pos": 5965419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044723.1", "url": "https://www.ensembl.org/id/ENSGALT00010044723.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026645.1", "url": "https://www.ensembl.org/id/ENSGALP00010026645.1" } ] } }, { "isoform_ac": "E1C1V6-1", "url": "https://www.uniprot.org/uniprotkb/E1C1V6/entry#E1C1V6-1", "sequence": { "sequence": "MGPSEEERERDVILISDDEDDGTLGNSVLIVDPLAKTALEEKKCEEVVDEECELMVTFCKQANVMPHARYDCTIHSFERMECETCSPIGKNADFCNQCYCYICDKLASECQIWTTSSLCHCNAHNKSKFWKDQRDFALAGVLVMFNLELTDIDADLRHGGNLLVSFIQELSVEYNKYLIGERIASTEHECFCVSKLPPGQCDTCRSRSTEIVYKYSGVFALVTRFLNQAEGESPKAAAVMLLGAAREITLHKDPALSWQNLGHTASLKLAVPCLLQRITTRLQKMLVLCDFPKSLYEKFINFFQSISLPCHCFAFSNSLNVVPWDHVLLTTVLKGQNTTGQRTQKGRKMFLWEVLPVIEARVEKLVENMNYKEVVRYLRAVKCNDTKGLRDLRDKIPFYLCKTGDFLDATHSLLFPINSLACCTACRLTPLQFEVYLKMFRTGSVPLGKDIQDPGPWVTVGSPMKDGVLIKQAFKLLYSNLSLYRNPKCWGSFIMIMGSSCFLGRNGHLRPLTVKEPPIAFQQGVLVASDGLFQELKAKINVSFPPGIFSQLHQEACLILAVQAVQQMVICELPYLTSFLEIFLAFGNNFWALRLLLNHLSYDECILRGIVNLVLRDLNRQKATMLKLWQNLGPQYVGEFICLFLTCRNRILQSIGVLALDIITENLHVCPWAKHLCNFFHNAGLMHLPLGATTHHEVSKFMDILEKL", "length": 708, "header": "tr|E1C1V6-1|E1C1V6_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC416530 PE=4 SV=3 CANONICAL=E1C1V6-1" }, "locus": { "chromosome": "14", "start_pos": 5977662, "end_pos": 5965419, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044728.1", "url": "https://www.ensembl.org/id/ENSGALT00010044728.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026650.1", "url": "https://www.ensembl.org/id/ENSGALP00010026650.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 459, "start_aa": "Thr", "end_pos": 459, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr459", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416530", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416530", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C1V6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 708, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C1V6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C1V6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 459 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C2A8-1", "uniprot_ac": "E1C2A8", "uniprot_id": "E1C2A8_CHICK", "mass": { "chemical_mass": 58644.0, "monoisotopic_mass": 58644.0 }, "refseq": { "ac": "XP_015137385", "name": "islet cell autoantigen 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137385" }, "gene_names": [ { "name": "ICA1", "type": "recommended", "evidence": [ { "id": "E1C2A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2A8" } ] }, { "name": "ICA1", "type": "synonym", "evidence": [ { "id": "XP_015137385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137385" } ] } ], "protein_names": [ { "name": "Islet cell autoantigen 1", "type": "synonym", "evidence": [ { "id": "E1C2A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2A8/entry#names_and_taxonomy" } ] }, { "name": "islet cell autoantigen 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015137385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137385" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015137385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137385" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C2A8", "url": "https://www.uniprot.org/uniprotkb/E1C2A8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ICA1", "url": "https://www.uniprot.org/uniprotkb/E1C2A8", "locus": { "chromosome": "2", "start_pos": 24858796, "end_pos": 24943602, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010003990", "url": "https://www.ensembl.org/id/ENSGALG00010003990" } ] } } ], "crossref": [ { "id": "E1C2A8", "url": "https://alphafold.ebi.ac.uk/entry/E1C2A8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010708", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010708", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420581", "url": "https://www.ncbi.nlm.nih.gov/gene/420581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420581", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420581", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E1C2A8", "url": "https://www.orthodb.org/?gene=E1C2A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10164:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10164:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015137385", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015137385", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C2A8", "url": "https://www.uniprot.org/uniprotkb/E1C2A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2A8-1", "url": "https://www.uniprot.org/uniprotkb/E1C2A8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGHKYNYPREFYDQYAQSQEKSVVNKMQQKYWKTKQTLIKVTGKKEDEHVVASDADLDAKLELFHSIQRTCMELLKAIELYQKRICFLSQEENELGKFLRSQGSQDKTRAGKMMQATGKALCFSSQQRLALRAPLTRLYQEVETFRYRAISDTWLTVNRMEQYRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQAQVRHAKLNFDKLKTDVCQKVDLLGASRCNLLSHVLTTYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTMLKSLQDPVNKLRETAEKEDLQTESTKSEDQQSQLISLDEESHTKEPDYSAHDGKDTLSKLQGNCNHKQNSGAVDDLLDLQPEENASKDQFAKSLESESSDKDDMVLLNEILNASSLEEGEFSKEWTAVFGQVTDLAMNSSAGDGDNTSAVASTPSGYLPSQLLDQNMNDLQSSLHGWAANSASPLSIPQPAQKPNSLNVNANKTPMKGEPTRNPKDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA", "length": 516, "header": "tr|E1C2A8-1|E1C2A8_CHICK Isoform 1 of Islet cell autoantigen 1 OS=Gallus gallus OX=9031 GN=ICA1 PE=4 SV=3 CANONICAL=E1C2A8-1" }, "isoforms": [ { "isoform_ac": "E1C2A8-1", "url": "https://www.uniprot.org/uniprotkb/E1C2A8/entry#E1C2A8-1", "sequence": { "sequence": "MDGHKYNYPREFYDQYAQSQEKSVVNKMQQKYWKTKQTLIKVTGKKEDEHVVASDADLDAKLELFHSIQRTCMELLKAIELYQKRICFLSQEENELGKFLRSQGSQDKTRAGKMMQATGKALCFSSQQRLALRAPLTRLYQEVETFRYRAISDTWLTVNRMEQYRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQAQVRHAKLNFDKLKTDVCQKVDLLGASRCNLLSHVLTTYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTMLKSLQDPVNKLRETAEKEDLQTESTKSEDQQSQLISLDEESHTKEPDYSAHDGKDTLSKLQGNCNHKQNSGAVDDLLDLQPEENASKDQFAKSLESESSDKDDMVLLNEILNASSLEEGEFSKEWTAVFGQVTDLAMNSSAGDGDNTSAVASTPSGYLPSQLLDQNMNDLQSSLHGWAANSASPLSIPQPAQKPNSLNVNANKTPMKGEPTRNPKDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA", "length": 516, "header": "tr|E1C2A8-1|E1C2A8_CHICK Isoform 1 of Islet cell autoantigen 1 OS=Gallus gallus OX=9031 GN=ICA1 PE=4 SV=3 CANONICAL=E1C2A8-1" }, "locus": { "chromosome": "2", "start_pos": 24918026, "end_pos": 24859590, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010009247.1", "url": "https://www.ensembl.org/id/ENSGALT00010009247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005466.1", "url": "https://www.ensembl.org/id/ENSGALP00010005466.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 421, "start_aa": "Thr", "end_pos": 421, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr421", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:420581", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420581", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "membrane bending", "id": "GO:0097753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097753", "evidence": [ { "database": "UniProtKB", "id": "E1C2A8", "url": "https://www.uniprot.org/uniprotkb/E1C2A8" } ], "pmid": "" }, { "name": "regulation of secretion", "id": "GO:0051046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051046", "evidence": [ { "database": "UniProtKB", "id": "E1C2A8", "url": "https://www.uniprot.org/uniprotkb/E1C2A8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "E1C2A8", "url": "https://www.uniprot.org/uniprotkb/E1C2A8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", 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This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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[ { "id": "E1C2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2K8/entry#names_and_taxonomy" } ] }, { "name": "angiopoietin-related protein 5 precursor", "type": "synonym", "evidence": [ { "id": "NP_001184165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184165" } ] }, { "name": "angiopoietin-related protein 5", "type": "synonym", "evidence": [ { "id": "NP_001184165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184165" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR12888536.226679.1, SRR12888520.105417.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000027.1. On Oct 16, 2010 this sequence version replaced XP_001235237.1. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record are predicted based on partial chicken transcript alignments and on full-length homologous protein alignment with human NP_835228.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001184165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184165" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C2K8", "url": "https://www.uniprot.org/uniprotkb/E1C2K8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANGPTL5", "url": "https://www.uniprot.org/uniprotkb/E1C2K8", "locus": { "chromosome": "1", "start_pos": 182689414, "end_pos": 182675080, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010007937", "url": "https://www.ensembl.org/id/ENSGALG00010007937" } ] } } ], "crossref": [ { "id": "E1C2K8", "url": "https://alphafold.ebi.ac.uk/entry/E1C2K8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017191", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017191", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "772036", "url": "https://www.ncbi.nlm.nih.gov/gene/772036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:772036", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EKHSICG", "url": "https://omabrowser.org/oma/group/EKHSICG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C2K8", "url": "https://www.orthodb.org/?gene=E1C2K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001184165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001184165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C2K8", "url": "https://www.uniprot.org/uniprotkb/E1C2K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2K8-1", "url": "https://www.uniprot.org/uniprotkb/E1C2K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSFRVTSLISLSVLLLGWGETVISDVKPCSSKGTRNVGAVEEPLKAEEKNKSADISKQKEQCLVPCDVQAKILRGEKQYMCRNLQSSLVEYARSTKKLVRNMMDDQQSSLDYLSNQVNELMNRVLLLNAEVLRKHLDPLPYKTVQSHGLDCTDIKDTIGSVSKTPSGLYIIHPEGSNYAFEVLCDMDFQGGGWTVLQKRTDGIITFQRTWSEYLDGFGDLSGEFWIGLRKIFYIVNQKATTFSLYVDLESENDKHAYASYDAFWIEDEACSFKIHLGRYSGNAGDAFRGYRKEDNQNSMPFSTFDVDNDGCRPVCTIKEQPVKSCSNFSDNTGWWFNQCGLANLNGIHRYTGRFLATGIHWDTWTVNNKPVKIKSVSMKIRRNYDPYFH", "length": 390, "header": "tr|E1C2K8-1|E1C2K8_CHICK Isoform 1 of Angiopoietin like 5 OS=Gallus gallus OX=9031 GN=ANGPTL5 PE=4 SV=1 CANONICAL=E1C2K8-1" }, "isoforms": [ { "isoform_ac": "E1C2K8-1", "url": "https://www.uniprot.org/uniprotkb/E1C2K8/entry#E1C2K8-1", "sequence": { "sequence": "MNSFRVTSLISLSVLLLGWGETVISDVKPCSSKGTRNVGAVEEPLKAEEKNKSADISKQKEQCLVPCDVQAKILRGEKQYMCRNLQSSLVEYARSTKKLVRNMMDDQQSSLDYLSNQVNELMNRVLLLNAEVLRKHLDPLPYKTVQSHGLDCTDIKDTIGSVSKTPSGLYIIHPEGSNYAFEVLCDMDFQGGGWTVLQKRTDGIITFQRTWSEYLDGFGDLSGEFWIGLRKIFYIVNQKATTFSLYVDLESENDKHAYASYDAFWIEDEACSFKIHLGRYSGNAGDAFRGYRKEDNQNSMPFSTFDVDNDGCRPVCTIKEQPVKSCSNFSDNTGWWFNQCGLANLNGIHRYTGRFLATGIHWDTWTVNNKPVKIKSVSMKIRRNYDPYFH", "length": 390, "header": "tr|E1C2K8-1|E1C2K8_CHICK Isoform 1 of Angiopoietin like 5 OS=Gallus gallus OX=9031 GN=ANGPTL5 PE=4 SV=1 CANONICAL=E1C2K8-1" }, "locus": { "chromosome": "1", "start_pos": 182688473, "end_pos": 182675164, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010018918.1", "url": "https://www.ensembl.org/id/ENSGALT00010018918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010010468.1", "url": "https://www.ensembl.org/id/ENSGALP00010010468.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:772036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772036", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SV75-1", "protein_name": "Angiopoietin like 5", "gene_name": "ANGPTL5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMYLFQASLLFLNLCIFTCGEAIRGNCVHHSTDSPVVNIVEDESNAKGENKSNDTVYKEDCEESCDVKSKIPREEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELMNRVLLLTTEVFRKQLDTFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGWTVIQKRIDGVIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTFAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGFCKEDNQNAVPFSTSDVDNDGCRPACFLNGQSVKSCSQLHNNTGWWFNQCGLSNLNGIHNFPGKFLATGIRWGTWTKNNSPVKIKSVSMKIRRIYDPYFK", "length": 388 }, "evidence": [ { "id": "E1C2K8", "url": "https://omabrowser.org/oma/group/E1C2K8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86XS5-1", "protein_name": "Angiopoietin-related protein 5", "gene_name": "ANGPTL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSPSQASLLFLNVCIFICGEAVQGNCVHHSTDSSVVNIVEDGSNAKDESKSNDTVCKEDCEESCDVKTKITREEKHFMCRNLQNSIVSYTRSTKKLLRNMMDEQQASLDYLSNQVNELMNRVLLLTTEVFRKQLDPFPHRPVQSHGLDCTDIKDTIGSVTKTPSGLYIIHPEGSSYPFEVMCDMDYRGGGRTVIQKRIDGIIDFQRLWCDYLDGFGDLLGEFWLGLKKIFYIVNQKNTSFMLYVALESEDDTLAYASYDNFWLEDETRFFKMHLGRYSGNAGDAFRGLKKEDNQNAMPFSTSDVDNDGCRPACLVNGQSVKSCSHLHNKTGWWFNECGLANLNGIHHFSGKLLATGIQWGTWTKNNSPVKIKSVSMKIRRMYNPYFK", "length": 388 }, "evidence": [ { "id": "E1C2K8", "url": "https://omabrowser.org/oma/group/E1C2K8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E1C2K8", "url": "https://www.uniprot.org/uniprotkb/E1C2K8" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1C2K8", "url": "https://www.uniprot.org/uniprotkb/E1C2K8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C2K8-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 390, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C2K8-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C2K8" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 328, "end_pos": 330 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C2L5-1", "uniprot_ac": "E1C2L5", "uniprot_id": "E1C2L5_CHICK", "mass": { "chemical_mass": 26696.0, "monoisotopic_mass": 26696.0 }, "refseq": { "ac": "NP_001264836", "name": "THO complex subunit 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264836" }, "gene_names": [ { "name": "ALYREF", "type": "recommended", "evidence": [ { "id": "E1C2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2L5" } ] }, { "name": "ALYREF", "type": "synonym", "evidence": [ { "id": "NP_001264836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264836" } ] }, { "name": "THOC4", "type": "synonym", "evidence": [ { "id": "NP_001264836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264836" } ] } ], "protein_names": [ { "name": "Aly/REF export factor", "type": "synonym", "evidence": [ { "id": "E1C2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2L5/entry#names_and_taxonomy" } ] }, { "name": "THO complex 4", "type": "synonym", "evidence": [ { "id": "NP_001264836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264836" } ] }, { "name": "THO complex subunit 4", "type": "synonym", "evidence": [ { "id": "NP_001264836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264836" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01022090.1, BU467731.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06143078, SAMN08016555 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000317.1. On Apr 28, 2013 this sequence version replaced XP_001232393.2. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264836", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264836" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C2L5", "url": "https://www.uniprot.org/uniprotkb/E1C2L5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALYREF", "url": "https://www.uniprot.org/uniprotkb/E1C2L5", "locus": { "chromosome": "18", "start_pos": 10573608, "end_pos": 10578367, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010029361", "url": "https://www.ensembl.org/id/ENSGALG00010029361" } ] } } ], "crossref": [ { "id": "E1C2L5", "url": "https://alphafold.ebi.ac.uk/entry/E1C2L5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007237", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007237", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12680", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12680", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769169", "url": "https://www.ncbi.nlm.nih.gov/gene/769169", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051229", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051229", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769169", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769169", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNDYPRD", "url": "https://omabrowser.org/oma/group/RNDYPRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C2L5", "url": "https://www.orthodb.org/?gene=E1C2L5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19965", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19965", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19965:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19965:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13865", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13865", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-159227", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159230", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264836", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C2L5", "url": "https://www.uniprot.org/uniprotkb/E1C2L5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2L5-1", "url": "https://www.uniprot.org/uniprotkb/E1C2L5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADKMDMSLDDIIKLNRSQRGGGRGGGRGGRGRGGVTRGGGPGRGGVGAGRAGGGPVRNRPVMARGGGRNRPAPYSRPKQLPEKWQHDLFDSGFGAGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSVNRGGMTRNRGGSGGFGGGGTRRGSRGGSRGRGRGAGRTSKQQLSAEELDAQLDAYNARMDTS", "length": 255, "header": "tr|E1C2L5-1|E1C2L5_CHICK Isoform 1 of Aly/REF export factor OS=Gallus gallus OX=9031 GN=ALYREF PE=1 SV=3 CANONICAL=E1C2L5-1" }, "isoforms": [ { "isoform_ac": "E1C2L5-1", "url": "https://www.uniprot.org/uniprotkb/E1C2L5/entry#E1C2L5-1", "sequence": { "sequence": "MADKMDMSLDDIIKLNRSQRGGGRGGGRGGRGRGGVTRGGGPGRGGVGAGRAGGGPVRNRPVMARGGGRNRPAPYSRPKQLPEKWQHDLFDSGFGAGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSVNRGGMTRNRGGSGGFGGGGTRRGSRGGSRGRGRGAGRTSKQQLSAEELDAQLDAYNARMDTS", "length": 255, "header": "tr|E1C2L5-1|E1C2L5_CHICK Isoform 1 of Aly/REF export factor OS=Gallus gallus OX=9031 GN=ALYREF PE=1 SV=3 CANONICAL=E1C2L5-1" }, "locus": { "chromosome": "18", "start_pos": 10578329, "end_pos": 10573880, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010071002.1", "url": "https://www.ensembl.org/id/ENSGALT00010071002.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010043693.1", "url": "https://www.ensembl.org/id/ENSGALP00010043693.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:769169", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769169", "resource": "KEGG Pathway" }, { "id": "R-GGA-159227", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159227", "resource": "Reactome", "description": "Transport of the SLBP independent Mature mRNA" }, { "id": "R-GGA-159230", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159230", "resource": "Reactome", "description": "Transport of the SLBP Dependant Mature mRNA" }, { "id": "R-GGA-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-GGA-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0RBB1-1", "protein_name": "Aly/REF export factor", "gene_name": "Alyref", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAVQAAARVNRGGGPMRNRPAIARGAAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRGGMTRNRGSGSFGGGGTRRGTRGGSRGRGRGTGRNSKQQLSAEELDAQLDAYNARMDTS", "length": 256 }, "evidence": [ { "id": "E1C2L5", "url": "https://omabrowser.org/oma/group/E1C2L5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08583-1", "protein_name": "THO complex subunit 4", "gene_name": "Alyref", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGAVQAAARVNRGGGPMRNRPAIARGAAGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSINRGGMTRNRGSGGFGGGGTRRGTRGGSRGRGRGTGRNSKQQLSAEELDAQLDAYNARMDTS", "length": 255 }, "evidence": [ { "id": "E1C2L5", "url": "https://omabrowser.org/oma/group/E1C2L5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3T0I4-1", "protein_name": "THO complex subunit 4", "gene_name": "ALYREF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGGAQAAARVNRGGGPIRNRPAIARGAAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDTQRRPAQSVNRGGMTRNRGSGGFGGGGGTRRGTRGGSRGRGRGTGRSSKQQLSAEELDAQLDAYNARMDTS", "length": 257 }, "evidence": [ { "id": "E1C2L5", "url": "https://omabrowser.org/oma/group/E1C2L5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86V81-1", "protein_name": "THO complex subunit 4", "gene_name": "ALYREF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADKMDMSLDDIIKLNRSQRGGRGGGRGRGRAGSQGGRGGGAQAAARVNRGGGPIRNRPAIARGAAGGGGRNRPAPYSRPKQLPDKWQHDLFDSGFGGGAGVETGGKLLVSNLDFGVSDADIQELFAEFGTLKKAAVHYDRSGRSLGTADVHFERKADALKAMKQYNGVPLDGRPMNIQLVTSQIDAQRRPAQSVNRGGMTRNRGAGGFGGGGGTRRGTRGGARGRGRGAGRNSKQQLSAEELDAQLDAYNARMDTS", "length": 257 }, "evidence": [ { "id": "E1C2L5", "url": "https://omabrowser.org/oma/group/E1C2L5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E1C2L5", "url": "https://www.uniprot.org/uniprotkb/E1C2L5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C2L5", "url": "https://www.uniprot.org/uniprotkb/E1C2L5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA export from nucleus", "id": "GO:0006406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406", "evidence": [ { "database": "UniProtKB", "id": "E1C2L5", "url": "https://www.uniprot.org/uniprotkb/E1C2L5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C2L5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 255, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C2L5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C2L5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 213 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C2V4-1", "uniprot_ac": "E1C2V4", "uniprot_id": "E1C2V4_CHICK", "mass": { "chemical_mass": 58591.0, "monoisotopic_mass": 58591.0 }, "refseq": { "ac": "XP_416361", "name": "synaptotagmin-10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416361" }, "gene_names": [ { "name": "SYT10", "type": "recommended", "evidence": [ { "id": "E1C2V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ] }, { "name": "SYT10", "type": "synonym", "evidence": [ { "id": "XP_416361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416361" } ] } ], "protein_names": [ { "name": "Synaptotagmin 10", "type": "synonym", "evidence": [ { "id": "E1C2V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2V4/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin-10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416361" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_416361.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416361" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYT10", "url": "https://www.uniprot.org/uniprotkb/E1C2V4", "locus": { "chromosome": "1", "start_pos": 58741851, "end_pos": 58685320, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010011050", "url": "https://www.ensembl.org/id/ENSGALG00010011050" } ] } } ], "crossref": [ { "id": "E1C2V4", "url": "https://alphafold.ebi.ac.uk/entry/E1C2V4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012911", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012911", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08403", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08403", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418129", "url": "https://www.ncbi.nlm.nih.gov/gene/418129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IWKDIHC", "url": "https://omabrowser.org/oma/group/IWKDIHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C2V4", "url": "https://www.orthodb.org/?gene=E1C2V4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_416361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416361", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2V4-1", "url": "https://www.uniprot.org/uniprotkb/E1C2V4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFPAEDGVGSLCHKALQIISELCLGGQVEREKCAGIFPLETARQGIGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWRSKPLTSNASNVPQSTSSAPTEVLETSEKKEVKENGKPTTKVLEAALKISHTSPDIPAEVQNALKEHLIRHARMQRQITEPTSSSRHNSFRRHLPRQMQVSSVDFNMGTDPILQRGETTTSIGRIKPELYKQKSVDSDGQQEDVKTCGKLNFTLRYDYENELLAVTIVKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPVFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREANVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGASDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGIDAEGLGRDHWNEMLAYPRKPITHWHPLVELPGRATSFDSQGSCSSPKPPLTP", "length": 522, "header": "tr|E1C2V4-1|E1C2V4_CHICK Isoform 1 of Synaptotagmin 10 OS=Gallus gallus OX=9031 GN=SYT10 PE=3 SV=3 CANONICAL=E1C2V4-1" }, "isoforms": [ { "isoform_ac": "E1C2V4-1", "url": "https://www.uniprot.org/uniprotkb/E1C2V4/entry#E1C2V4-1", "sequence": { "sequence": "MSFPAEDGVGSLCHKALQIISELCLGGQVEREKCAGIFPLETARQGIGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWRSKPLTSNASNVPQSTSSAPTEVLETSEKKEVKENGKPTTKVLEAALKISHTSPDIPAEVQNALKEHLIRHARMQRQITEPTSSSRHNSFRRHLPRQMQVSSVDFNMGTDPILQRGETTTSIGRIKPELYKQKSVDSDGQQEDVKTCGKLNFTLRYDYENELLAVTIVKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPVFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREANVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGASDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGIDAEGLGRDHWNEMLAYPRKPITHWHPLVELPGRATSFDSQGSCSSPKPPLTP", "length": 522, "header": "tr|E1C2V4-1|E1C2V4_CHICK Isoform 1 of Synaptotagmin 10 OS=Gallus gallus OX=9031 GN=SYT10 PE=3 SV=3 CANONICAL=E1C2V4-1" }, "locus": { "chromosome": "1", "start_pos": 58717295, "end_pos": 58685402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026464.1", "url": "https://www.ensembl.org/id/ENSGALT00010026464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015065.1", "url": "https://www.ensembl.org/id/ENSGALP00010015065.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1MRP4-1", "protein_name": "Synaptotagmin 10", "gene_name": "SYT10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFHKEDGVSSLCQKALHIVTELCFAGQVEWEKCSSIFPPDGGSQGGSNTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPFWKSKPMTFNVSTLPQSMSSAPTEVFETEEKKEIKENGEPAPKVIEPAIKISHTSPDIPAEVQTAVKEHVIKHARVQRQTTEPTSSSRHNSFRRHLPRQMQVSSVDFGMGTEPILQRGETTTSIGRIKPELYKQKSVDSEDNRKEDVKTCGKLNFTLQYDYENELLVVKIIKALDLPAKDFIGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIFDNLFEASDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDVTGSSDPYVKVSLMCEGRRLKKKKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAKGLGRDHWNEMLTYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPTSTP", "length": 523 }, "evidence": [ { "id": "E1C2V4", "url": "https://omabrowser.org/oma/group/E1C2V4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SGD3-1", "protein_name": "Synaptotagmin 10", "gene_name": "SYT10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSFHKEDGVSSLCQKALHIVTELCFAGQVEWEKCSSIFPPDRGSQGESSTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNVTTLPQSISSAPTEVFETEEKKEVKENGKPALKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTEPTSSSRHNSFRRHLPRQMQVSSVDFGMGTEPVLQRRETTTSIGRIKPELYKQKSVDSEGNRKEDVKTCGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKYQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEASDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP", "length": 523 }, "evidence": [ { "id": "E1C2V4", "url": "https://omabrowser.org/oma/group/E1C2V4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O08625-1", "protein_name": "Synaptotagmin-10", "gene_name": "Syt10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFRKEDGVSSLCQKALHIITELCFAGQVEWDKCSGIFPADRSGQGGGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKLVAPNVSTLPQSISSAPTEVFETEEKKEVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTDPTSSSRHNSFRRHLPRQMNVSSVDFSMGTEPVLQRGETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCSSPRPPSTP", "length": 523 }, "evidence": [ { "id": "E1C2V4", "url": "https://omabrowser.org/oma/group/E1C2V4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6XYQ8-1", "protein_name": "Synaptotagmin-10", "gene_name": "SYT10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFHKEDGVNSLCQKALHIVTELCFAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENEKPAVKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSTRHSSFRRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP", "length": 523 }, "evidence": [ { "id": "E1C2V4", "url": "https://omabrowser.org/oma/group/E1C2V4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0N4-1", "protein_name": "Synaptotagmin-10", "gene_name": "Syt10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFRKEDGVSSLCQKALHIITELCFAGQVEWDKCSGIFPADRSGQGGGGTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKLVAPNLSVLPQSISSAPTEVFETEEKKEVEENEKPAPKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQTTEPTSSSRHNSFRRHLPRQMNVSSVDFSVGTEPILQRGETRTSIGRIKPELYKQKSVDSEGNRKDDVKTCGKLNFALQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKIYLLPDRKKKFQTRVHRKTLNPLFDELFQFPVVYDQLSNRKLHFSIYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLCIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCSSPRPPSTP", "length": 523 }, "evidence": [ { "id": "E1C2V4", "url": "https://omabrowser.org/oma/group/E1C2V4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "E1C2V4", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C2V4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 522, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C2V4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C2V4" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C2V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2V4" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 351, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C2V6-1", "uniprot_ac": "E1C2V6", "uniprot_id": "E1C2V6_CHICK", "mass": { "chemical_mass": 51292.0, "monoisotopic_mass": 51292.0 }, "refseq": { "ac": "XP_418996", "name": "UPF0489 protein C5orf22 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418996" }, "gene_names": [ { "name": "C2H5ORF22", "type": "recommended", "evidence": [ { "id": "E1C2V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2V6" } ] }, { "name": "C2H5ORF22", "type": "synonym", "evidence": [ { "id": "XP_418996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418996" } ] } ], "protein_names": [ { "name": "Chromosome 5 open reading frame 22", "type": "synonym", "evidence": [ { "id": "E1C2V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2V6/entry#names_and_taxonomy" } ] }, { "name": "UPF0489 protein C5orf22 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_418996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418996" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_418996.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418996" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C2V6", "url": "https://www.uniprot.org/uniprotkb/E1C2V6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C2H5ORF22", "url": "https://www.uniprot.org/uniprotkb/E1C2V6", "locus": {} } ], "crossref": [ { "id": "E1C2V6", "url": "https://alphafold.ebi.ac.uk/entry/E1C2V6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012909", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012909", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420910", "url": "https://www.ncbi.nlm.nih.gov/gene/420910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420910", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIFWHLE", "url": "https://omabrowser.org/oma/group/RIFWHLE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C2V6", "url": "https://www.orthodb.org/?gene=E1C2V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13225:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13225:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C2V6", "url": "https://www.uniprot.org/uniprotkb/E1C2V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C2V6-1", "url": "https://www.uniprot.org/uniprotkb/E1C2V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAAAACGPRPRGGGMRAYPALPVWVVEDHQDVLPFIYRAIGSKHLPASNISFVHLDSHPDLLIPVNMPADTVFDKEALFNELSIENWIMPAVYAGHISQVVWLHPPWAQQISEGKHNFFVGKDISTTTIRVTGTDHYFLSDGLYVPADQLENPKPLNLHVVLINPTEASNSQEENDKVASAKRLKLNTDDTANTAATSSSVAPGDHDNNFSSVKNKEVQHASALNRAKMLPECSASSSLRKNECPVREVAKDICQVLQNGDAFVLDIDLDFFSVKNPFKEMYTKTEYELLQELYNFKKPHSNATEEDLLDCVENRVHQLEDLEAAFADFCDNDDEETLQKWASYPGLKPLVQLVHSLKSRMESPDYEMVHQAGLTCDYVELPHHVSTKEEIEGLLQSIRVLLKDMPKPTLVTIARSSLDDYCPSEQVDVIQEKVLSLLGFIYGTLDVHLDYSSNSSSL", "length": 460, "header": "tr|E1C2V6-1|E1C2V6_CHICK Isoform 1 of Chromosome 5 open reading frame 22 OS=Gallus gallus OX=9031 GN=C2H5ORF22 PE=3 SV=1 CANONICAL=E1C2V6-1" }, "isoforms": [ { "isoform_ac": "E1C2V6-1", "url": "https://www.uniprot.org/uniprotkb/E1C2V6/entry#E1C2V6-1", "sequence": { "sequence": "MSGAAAACGPRPRGGGMRAYPALPVWVVEDHQDVLPFIYRAIGSKHLPASNISFVHLDSHPDLLIPVNMPADTVFDKEALFNELSIENWIMPAVYAGHISQVVWLHPPWAQQISEGKHNFFVGKDISTTTIRVTGTDHYFLSDGLYVPADQLENPKPLNLHVVLINPTEASNSQEENDKVASAKRLKLNTDDTANTAATSSSVAPGDHDNNFSSVKNKEVQHASALNRAKMLPECSASSSLRKNECPVREVAKDICQVLQNGDAFVLDIDLDFFSVKNPFKEMYTKTEYELLQELYNFKKPHSNATEEDLLDCVENRVHQLEDLEAAFADFCDNDDEETLQKWASYPGLKPLVQLVHSLKSRMESPDYEMVHQAGLTCDYVELPHHVSTKEEIEGLLQSIRVLLKDMPKPTLVTIARSSLDDYCPSEQVDVIQEKVLSLLGFIYGTLDVHLDYSSNSSSL", "length": 460, "header": "tr|E1C2V6-1|E1C2V6_CHICK Isoform 1 of Chromosome 5 open reading frame 22 OS=Gallus gallus OX=9031 GN=C2H5ORF22 PE=3 SV=1 CANONICAL=E1C2V6-1" }, "locus": { "chromosome": "2", "start_pos": 68902348, "end_pos": 68891343, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026408.1", "url": "https://www.ensembl.org/id/ENSGALT00010026408.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010015026.1", "url": "https://www.ensembl.org/id/ENSGALP00010015026.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420910", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420910", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M9PI97-1", "protein_name": "Misexpression suppressor of ras 6, isoform B", "gene_name": "MESR6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESDTLDQESAAAALKKLSPSESPESSKKWEPTSGEWVAAGGGEEAPPTKRQKTADEKEENREEDEDSEESVDEEEDDGEGIVQIGGTISPRHFQRIPVFIVDYHNDVLEFIYRCFATRHLPLQNNTLVHFDSHPDLVIPRHIAASSTYQKETMLNELSIENWIMPTLYAEIENNVKGQIKKFYGHFNRVVWLKNSWCQQLPTGRHDFKVGQKDDRIGVDCPLDYFIADGNYCTTEDLQDAKSVELQVHDADNESLNPNEFLTEKDAKGFVLDIDLDFFSTSNPFLEIYKDADCYNQLKEIFHFESVEKVKKSGTATIADYLATAERRQTQLDALKTIFWHLEEERNFEGLEKPDETVVTPEVYAKIVKLADQLQEKYPDDEIDWHLIFDSGSTTDNNGLPHHISIAEELETYFANFKRFLQRLPVPPVAITMAHSAQDDYCPQDQVAFIEECVLRLLKEVFGERLHDKAILHYMDDPWDVMKL", "length": 484 }, "evidence": [ { "id": "E1C2V6", "url": "https://omabrowser.org/oma/group/E1C2V6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q49AR2-1", "protein_name": "UPF0489 protein C5orf22", "gene_name": "C5orf22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSAGGRAGLRRYPKLPVWVVEDHQEVLPFIYRAIGSKHLPASNVSFLHFDSHPDLLIPVNMPADTVFDKETLFGELSIENWIMPAVYAGHFSHVIWFHPTWAQQIREGRHHFLVGKDTSTTTIRVTSTDHYFLSDGLYVPEDQLENQKPLQLDVIMVKPYKLCNNQEENDAVSSAKKPKLALEDSENTASTNCDSSSEGLEKDTATQRSDQTCLEPSCSCSSENQECQTAASTGEILEILKKGKAFVLDIDLDFFSVKNPFKEMFTQEEYKILQELYQFKKPGTNLTEEDLVDIVDTRIHQLEDLEATFADLCDGDDEETVQRWASNPGMESLVPLVQSLKKRMEVPDYEMVHQAGLTCDYSELPHHISTEQEIECLIQSVHYLLKNLPNPTLVTIARSSLDDYCPSDQVDTIQEKVLNMLRALYGNLDLQVYAAESPPS", "length": 442 }, "evidence": [ { "id": "E1C2V6", "url": "https://omabrowser.org/oma/group/E1C2V6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BGC1-1", "protein_name": "UPF0489 protein C5orf22 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDTGGDRARLRRYTKLPVWVVEDHQEVLPFIYRAIGSKHLPDSNISFLHLDSHPDLLIPVNMPADTVFDKEALFGELSIENWIMPAVYAGHFSQVIWLHPTWAQQIREGKHCFLVGKDISTTTIRVTSTDSYFLSDGLFVPEDQLENRRPLQLDVILVEPYTLCSKQDDSDSVSSTKKPKLALGSGESSAAADGHSCSEGRRGDAVTPRSDHACQEPSCSRSGGQQSQNTATAGAILDILKTGDAFVLDIDLDFFSVKNPFKEMFTQDEYKILQELYQFKKPDSNLPEDGLVDVVEARTHQLEDLEAVFADLCDGDSEETVQSWASNPGMESLVPLVQSLKKRMEVPDYEMVHQAGLTCDYSELPHHISTEEEIEYLIQSVYFLLKSLPKPTLVTIARSSLDDYCPPEQVDMIQGKVLDVLHSLYGTLDTHLVYSEESPLS", "length": 442 }, "evidence": [ { "id": "E1C2V6", "url": "https://omabrowser.org/oma/group/E1C2V6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C2V6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 460, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C2V6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C2V6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C345-1", "uniprot_ac": "E1C345", "uniprot_id": "E1C345_CHICK", "mass": { "chemical_mass": 21217.0, "monoisotopic_mass": 21217.0 }, "refseq": { "ac": "XP_001234023", "name": "transmembrane 4 L6 family member 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234023" }, "gene_names": [ { "name": "TM4SF4", "type": "recommended", "evidence": [ { "id": "E1C345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C345" } ] }, { "name": "TM4SF4", "type": "synonym", "evidence": [ { "id": "XP_001234023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234023" } ] } ], "protein_names": [ { "name": "Transmembrane 4 L six family member 4", "type": "synonym", "evidence": [ { "id": "E1C345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C345/entry#names_and_taxonomy" } ] }, { "name": "transmembrane 4 L6 family member 4", "type": "synonym", "evidence": [ { "id": "XP_001234023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234023" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001234023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234023" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C345", "url": "https://www.uniprot.org/uniprotkb/E1C345" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TM4SF4", "url": "https://www.uniprot.org/uniprotkb/E1C345", "locus": { "chromosome": "9", "start_pos": 23555188, "end_pos": 23559833, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010001129", "url": "https://www.ensembl.org/id/ENSGALG00010001129" } ] } } ], "crossref": [ { "id": "E1C345", "url": "https://alphafold.ebi.ac.uk/entry/E1C345", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010427", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010427", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "771806", "url": "https://www.ncbi.nlm.nih.gov/gene/771806", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771806", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771806", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGCCGNQ", "url": "https://omabrowser.org/oma/group/CGCCGNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C345", "url": "https://www.orthodb.org/?gene=E1C345", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14198:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14198:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001234023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001234023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C345", "url": "https://www.uniprot.org/uniprotkb/E1C345", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C345-1", "url": "https://www.uniprot.org/uniprotkb/E1C345-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCTGSCAKCLGTTLIPLAVLCTVANILLFFPGGKVAEQNDHITDEVWYFGGILGSGVLMIFPALVFLGLKNNDCCGCCGNESCGKRFAMFSSIIFAAVGVVGAGYCFVVSAVAINRGPKCHNGILWLYPFKDGDYLSDQKMWDMCLSPANIVPWHLTLFALLLVMSGIQAVLCGIQVVNGLFGTICGDCRCCGCCGGDGPV", "length": 201, "header": "tr|E1C345-1|E1C345_CHICK Isoform 1 of Transmembrane 4 L six family member 4 OS=Gallus gallus OX=9031 GN=TM4SF4 PE=3 SV=1 CANONICAL=E1C345-1" }, "isoforms": [ { "isoform_ac": "E1C345-1", "url": "https://www.uniprot.org/uniprotkb/E1C345/entry#E1C345-1", "sequence": { "sequence": "MCTGSCAKCLGTTLIPLAVLCTVANILLFFPGGKVAEQNDHITDEVWYFGGILGSGVLMIFPALVFLGLKNNDCCGCCGNESCGKRFAMFSSIIFAAVGVVGAGYCFVVSAVAINRGPKCHNGILWLYPFKDGDYLSDQKMWDMCLSPANIVPWHLTLFALLLVMSGIQAVLCGIQVVNGLFGTICGDCRCCGCCGGDGPV", "length": 201, "header": "tr|E1C345-1|E1C345_CHICK Isoform 1 of Transmembrane 4 L six family member 4 OS=Gallus gallus OX=9031 GN=TM4SF4 PE=3 SV=1 CANONICAL=E1C345-1" }, "locus": { "chromosome": "9", "start_pos": 23559658, "end_pos": 23555654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010002563.1", "url": "https://www.ensembl.org/id/ENSGALT00010002563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010001113.1", "url": "https://www.ensembl.org/id/ENSGALP00010001113.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771806", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771806", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SJP1-1", "protein_name": "Transmembrane 4 L six family member 4", "gene_name": "TM4SF4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCTGSCAKCLGGTLIPLTVFGFLANILLFFPGGKVIDNNDHLSDEVWLFGGILGSGVLMIFPALVFLGLKNNDCCGCCGNESCGKRFAMFTSTIFAVVGFLGAGYSFIISAVSINKGPKCFIARNSTWGYPFQDGDYLSNRDLWSNCQKPDNVVPWNLTLFSILLITGGVQMLICAIQVINGLLGTLCGDCQCCGCCRGDGPV", "length": 203 }, "evidence": [ { "id": "E1C345", "url": "https://omabrowser.org/oma/group/E1C345/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P48230-1", "protein_name": "Transmembrane 4 L6 family member 4", "gene_name": "TM4SF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCTGGCARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMIFPALVFLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLMANSTWGYPFHDGDYLNDEALWNKCREPLNVVPWNLTLFSILLVVGGIQMVLCAIQVVNGLLGTLCGDCQCCGCCGGDGPV", "length": 202 }, "evidence": [ { "id": "E1C345", "url": "https://omabrowser.org/oma/group/E1C345/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQL5-1", "protein_name": "Transmembrane 4 L6 family member 4", "gene_name": "Tm4sf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCTGGCARCLGGTLIPLAVFAVLANILLFFPGGKVVDDNSHLSDEVWYFGGILGSGVLMIFPALVFLGLQNNDCCGCCGNESCGKRFAMFTSTLFAVVGFLGAAYSFIVSAVSINKGPKCFMTNNTWGYPFHDGDYLNDQALWSKCEEPRDVVPWNLTLFSILLVIGGIQMVLCAIQVINGLLGTLCGDCQCCGCCGGDRPV", "length": 202 }, "evidence": [ { "id": "E1C345", "url": "https://omabrowser.org/oma/group/E1C345/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1C345", "url": "https://www.uniprot.org/uniprotkb/E1C345" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C345-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 201, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C345-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C345" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C353-1", "uniprot_ac": "E1C353", "uniprot_id": "E1C353_CHICK", "mass": { "chemical_mass": 72629.0, "monoisotopic_mass": 72629.0 }, "refseq": { "ac": "NP_001280063", "name": "collagen alpha-1(VIII) chain precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280063" }, "gene_names": [ { "name": "COL8A1", "type": "recommended", "evidence": [ { "id": "E1C353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C353" } ] }, { "name": "COL8A1", "type": "synonym", "evidence": [ { "id": "NP_001280063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280063" } ] } ], "protein_names": [ { "name": "Collagen type VIII alpha 1 chain", "type": "synonym", "evidence": [ { "id": "E1C353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C353/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(VIII) chain precursor", "type": "synonym", "evidence": [ { "id": "NP_001280063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280063" } ] }, { "name": "collagen alpha-1(VIII) chain", "type": "synonym", "evidence": [ { "id": "NP_001280063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280063" } ] }, { "name": "collagen, type VIII, alpha 1", "type": "synonym", "evidence": [ { "id": "NP_001280063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280063" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267658.4701.1, SRR13267659.211316.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992393 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000019.1. On Sep 23, 2021 this sequence version replaced NP_001280063.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001280063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280063" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C353", "url": "https://www.uniprot.org/uniprotkb/E1C353" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL8A1", "url": "https://www.uniprot.org/uniprotkb/E1C353", "locus": { "chromosome": "1", "start_pos": 84514042, "end_pos": 84600852, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010005474", "url": "https://www.ensembl.org/id/ENSGALG00010005474" } ] } } ], "crossref": [ { "id": "E1C353", "url": "https://alphafold.ebi.ac.uk/entry/E1C353", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015253", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015253", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418378", "url": "https://www.ncbi.nlm.nih.gov/gene/418378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418378", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMGKEMP", "url": "https://omabrowser.org/oma/group/PMGKEMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XLR1", "url": "https://www.orthodb.org/?gene=A0A8V0XLR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C353", "url": "https://www.orthodb.org/?gene=E1C353", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001280063", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280063", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XLR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XLR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C353", "url": "https://www.uniprot.org/uniprotkb/E1C353", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C353-1", "url": "https://www.uniprot.org/uniprotkb/E1C353-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVLLIPTQLLAVAVAISLQLVRSTQGGVYYGIKQLPPQVPQYQALGQQVPHMPLGKEGIPMQHMGKEVPHMQYGKEYPHLPQYMKEVPQVPMLGKDMAPKKEKEIPMRSLRGEQGPPGEPGPRGPPGPPGLPGHGVPGAKGKPGPQGYPGIGKPGLPGMPGKPGVMGPPGPRGEMGPKGEVGPMGIPGPQGPPGPHGLPGIGKAGAPGLQGQPGPKGEPGMKGPPGVPGIPGPKGEKGVGIPGLPGLKGPPGLPGPPGPVGLPGVGKPGMVGFPGPQGPVGKPGPPGELGLQGPPGVPGMQGPPGLPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGERGVGGLPGPLGPKGEKGHAGPPGMGGPPGEPGQPGLPGIMGPPGAVGFPGPKGEGGAVGPPGPVGPKGEPGLQGFPGKPGFPGEVGAPGLRGLPGPTGPKGEAGHKGLPGLPGVPGLVGPKGEPGLPGAQGLQGPSGIPGIAGPSGPIGPPGLPGAKGEPGQPGPPGFPGVGKPGAAGLQGPPGKPGALGPPGQPGLQGPPGPPGPPGPPVIIPPTPPAAGQYLPEVGPGIDGLKPPYGYAGKKGKAGGAVYEMPAFTAELLTPFPRVGVPVKFDKLLYNGRQNYNPATGIFTCEIPGIYYFAYHVHCKGASVWVALFKNNEPLMYTYDEYKKGFLDQASGSAVVQLMPGDKVYVQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 739, "header": "tr|E1C353-1|E1C353_CHICK Isoform 1 of Collagen type VIII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL8A1 PE=4 SV=1 CANONICAL=E1C353-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XLR1-1", "url": "https://www.uniprot.org/uniprotkb/E1C353/entry#A0A8V0XLR1-1", "sequence": { "sequence": "MAVLLIPTQLLAVAVAISLQLVRSTQGGVYYGIKQLPPQVPMLGKDMAPKKEKEIPMRSLRGEQGPPGEPGPRGPPGPPGLPGHGVPGAKGKPGPQGYPGIGKPGLPGMPGKPGVMGPPGPRGEMGPKGEVGPMGIPGPQGPPGPHGLPGIGKAGAPGLQGQPGPKGEPGMKGPPGVPGIPGPKGEKGVGIPGLPGLKGPPGLPGPPGPVGLPGVGKPGMVGFPGPQGPVGKPGPPGELGLQGPPGVPGMQGPPGLPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGERGVGGLPGPLGPKGEKGHAGPPGMGGPPGEPGQPGLPGIMGPPGAVGFPGPKGEGGAVGPPGPVGPKGEPGLQGFPGKPGFPGEVGAPGLRGLPGPTGPKGEAGHKGLPGLPGVPGLVGPKGEPGLPGAQGLQGPSGIPGIAGPSGPIGPPGLPGAKGEPGQPGPPGFPGVGKPGAAGLQGPPGKPGALGPPGQPGLQGPPGPPGPPGPPVIIPPTPPAAGQYLPEVGPGIDGLKPPYGYAGKKGKAGGAVYEMPAFTAELLTPFPRVGVPVKFDKLLYNGRQNYNPATGIFTCEIPGIYYFAYHVHCKGASVWVALFKNNEPLMYTYDEYKKGFLDQASGSAVVQLMPGDKVYVQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 688, "header": "tr|A0A8V0XLR1-1|A0A8V0XLR1_CHICK Computationally mapped isoform of Collagen type VIII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL8A1 PE=4 SV=1 CANONICAL=E1C353-1" }, "locus": { "chromosome": "1", "start_pos": 84519282, "end_pos": 84515714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013065.1", "url": "https://www.ensembl.org/id/ENSGALT00010013065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007627.1", "url": "https://www.ensembl.org/id/ENSGALP00010007627.1" } ] } }, { "isoform_ac": "E1C353-1", "url": "https://www.uniprot.org/uniprotkb/E1C353/entry#E1C353-1", "sequence": { "sequence": "MAVLLIPTQLLAVAVAISLQLVRSTQGGVYYGIKQLPPQVPQYQALGQQVPHMPLGKEGIPMQHMGKEVPHMQYGKEYPHLPQYMKEVPQVPMLGKDMAPKKEKEIPMRSLRGEQGPPGEPGPRGPPGPPGLPGHGVPGAKGKPGPQGYPGIGKPGLPGMPGKPGVMGPPGPRGEMGPKGEVGPMGIPGPQGPPGPHGLPGIGKAGAPGLQGQPGPKGEPGMKGPPGVPGIPGPKGEKGVGIPGLPGLKGPPGLPGPPGPVGLPGVGKPGMVGFPGPQGPVGKPGPPGELGLQGPPGVPGMQGPPGLPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGERGVGGLPGPLGPKGEKGHAGPPGMGGPPGEPGQPGLPGIMGPPGAVGFPGPKGEGGAVGPPGPVGPKGEPGLQGFPGKPGFPGEVGAPGLRGLPGPTGPKGEAGHKGLPGLPGVPGLVGPKGEPGLPGAQGLQGPSGIPGIAGPSGPIGPPGLPGAKGEPGQPGPPGFPGVGKPGAAGLQGPPGKPGALGPPGQPGLQGPPGPPGPPGPPVIIPPTPPAAGQYLPEVGPGIDGLKPPYGYAGKKGKAGGAVYEMPAFTAELLTPFPRVGVPVKFDKLLYNGRQNYNPATGIFTCEIPGIYYFAYHVHCKGASVWVALFKNNEPLMYTYDEYKKGFLDQASGSAVVQLMPGDKVYVQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 739, "header": "tr|E1C353-1|E1C353_CHICK Isoform 1 of Collagen type VIII alpha 1 chain OS=Gallus gallus OX=9031 GN=COL8A1 PE=4 SV=1 CANONICAL=E1C353-1" }, "locus": { "chromosome": "1", "start_pos": 84519282, "end_pos": 84515714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010013066.1", "url": "https://www.ensembl.org/id/ENSGALT00010013066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010007628.1", "url": "https://www.ensembl.org/id/ENSGALP00010007628.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 453, "start_aa": "Thr", "end_pos": 453, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr453", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 572, "start_aa": "Thr", "end_pos": 572, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr572", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418378", "resource": "KEGG Pathway" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0PXW0-1", "protein_name": "Collagen type VIII alpha 1 chain", "gene_name": "COL8A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGPPAPLQLLGVLLTISLGSIQLIQAGAYYGIKPLPPQIPPQIPPQIPQYQPLGQQVPHIPLGKDGLNVGKELPHMQYGKEYPHLPQYMKEIQPAPRMGKEAAPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGQGIPGIKGKPGPQGYPGIGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGVGGLPGALGPRGEKGPVGAPGLGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGVVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGAPGLLGPKGEPGIPGDQGLQGPPGIPGIAGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPHGEYLPDMGLGIDGAKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFDKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 744 }, "evidence": [ { "id": "E1C353", "url": "https://omabrowser.org/oma/group/E1C353/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AA24-1", "protein_name": "Collagen type VIII alpha 1 chain", "gene_name": "Col8a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVPPRPLQLLGILFILSLSSVRLAQAGAYYGIKPLPPQIPPQIPPQIPQYQPLGQQVPHMPLGKDGLSMGKEMPHMQYGKEYPHLPQYMKEIQPVPRVGKEVVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGMPGIKGKPGPQGYPGIGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPVGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIAGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPSPQGEYLPDMGLGIDGVKPPHAYAGKKGKNGGPYEMPAFTAELTVPFPPVGAPVKFDKLLYNGRQNYNPQTGVFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 743 }, "evidence": [ { "id": "E1C353", "url": "https://omabrowser.org/oma/group/E1C353/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HMN0-1", "protein_name": "Collagen alpha-1(VIII) chain", "gene_name": "Col8a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVPPRPLQLLGVLLTISLNSIRLTQAGAYYGIKPLPPQIPPQIPPQIPQYQPLGQQVPHMPLGKDGLSMGKEMPHMQYGKEYPHLPQYMKEIQPVPRMGKEVVPKKGKGEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGMPGIKGKPGPQGYPGIGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGERGPKGLPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGIGKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGVPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGALGPRGEKGPIGAPGMGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGVIGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGIRGLPGPIGPKGEAGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIVGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYAGKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFDKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 745 }, "evidence": [ { "id": "E1C353", "url": "https://omabrowser.org/oma/group/E1C353/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27658-1", "protein_name": "Collagen alpha-1(VIII) chain", "gene_name": "COL8A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVLPGPLQLLGVLLTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 744 }, "evidence": [ { "id": "E1C353", "url": "https://omabrowser.org/oma/group/E1C353/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q00780-1", "protein_name": "Collagen alpha-1(VIII) chain", "gene_name": "Col8a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVPPRPLQLLGILFIISLNSVRLIQAGAYYGIKPLPPQIPPQIPPQIPQYQPLGQQVPHMPLGKDGLSMGKEMPHMQYGKEYPHLPQYMKEIPPVPRMGKEVVPKKGKGEVPLASLRGEQGPRGEPGPRGPPGPPGLPGHGMPGIKGKPGPQGYPGIGKPGMPGMPGKPGAMGMPGAKGEIGPKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGAKGERGPKGPPGPPGLQGPKGEKGFGMPGLPGLKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGPPGEPGPQGLIGVPGVQGPPGMPGVGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGVGKPGFPGPKGDRGIGGVPGVLGPRGEKGPIGAPGMGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGVVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEGGHKGLPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIVGPSGPIGPPGIPGPKGEPGLPGPPGFPGVGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPTPSPQGEYLPDMGLGIDGVKPPHAYAGKKGKHGGPAYEMPAFTAELTVPFPPVGAPVKFDKLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPMMYTYDEYKKGFLDQASGSAVLLLRPGDQVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM", "length": 744 }, "evidence": [ { "id": "E1C353", "url": "https://omabrowser.org/oma/group/E1C353/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E1C353", "url": "https://www.uniprot.org/uniprotkb/E1C353" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E1C353", "url": "https://www.uniprot.org/uniprotkb/E1C353" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "E1C353", "url": "https://www.uniprot.org/uniprotkb/E1C353" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "E1C353", "url": "https://www.uniprot.org/uniprotkb/E1C353" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "E1C353", "url": "https://www.uniprot.org/uniprotkb/E1C353" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C353-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 739, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C353-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C353" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 453, 572 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3J5-1", "uniprot_ac": "E1C3J5", "uniprot_id": "E1C3J5_CHICK", "mass": { "chemical_mass": 46302.0, "monoisotopic_mass": 46302.0 }, "refseq": { "ac": "XP_426188", "name": "failed axon connections homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426188" }, "gene_names": [ { "name": "FAXC", "type": "recommended", "evidence": [ { "id": "E1C3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3J5" } ] }, { "name": "FAXC", "type": "synonym", "evidence": [ { "id": "XP_426188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426188" } ] } ], "protein_names": [ { "name": "Failed axon connections homolog, metaxin like GST domain containing", "type": "synonym", "evidence": [ { "id": "E1C3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3J5/entry#names_and_taxonomy" } ] }, { "name": "failed axon connections homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_426188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426188" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_426188.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426188" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3J5", "url": "https://www.uniprot.org/uniprotkb/E1C3J5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAXC", "url": "https://www.uniprot.org/uniprotkb/E1C3J5", "locus": { "chromosome": "3", "start_pos": 71232265, "end_pos": 71215088, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010004345", "url": "https://www.ensembl.org/id/ENSGALG00010004345" } ] } } ], "crossref": [ { "id": "E1C3J5", "url": "https://alphafold.ebi.ac.uk/entry/E1C3J5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000015489", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000015489", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03080", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03080", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428630", "url": "https://www.ncbi.nlm.nih.gov/gene/428630", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428630", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0XMA3", "url": "https://www.orthodb.org/?gene=A0A8V0XMA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C3J5", "url": "https://www.orthodb.org/?gene=E1C3J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12289:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12289:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17172", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17172", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19333", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19333", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XMA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XMA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3J5", "url": "https://www.uniprot.org/uniprotkb/E1C3J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3J5-1", "url": "https://www.uniprot.org/uniprotkb/E1C3J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWGVGLAAPRSCVADLSRNRSLSLGWCAGPEEPPPALYGGELVAFPLAGAGAGGTMAALGSDSWWKKTLYLTGGALLAAAAYLLHELLAIRKEQEIDSKDAIILHQFSRPNNGVPSLSPFCLKMETYLRMADLPYQNYFDGKLSPQGKMPWIEYNHKKVSGTEFIIDFLEEKLGVNLNKNLGPRERAVSRAVTKMVEEHFYWTLAYCQWVENLHETQKMISVYGPLSDLLKWILCHLTKGIVKREMYGHGIGRFSEEEMYTLMEKDMRTLASLLGDKKYIMGPNLSTVDATVFGHLAQAMWTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTLYESEESSDASKTHSPLQDFSFYSRTETFDEEGNSISHTPDTDYTGHSLFDSDVDMDDYRDHEQCK", "length": 408, "header": "tr|E1C3J5-1|E1C3J5_CHICK Isoform 1 of Failed axon connections homolog, metaxin like GST domain containing OS=Gallus gallus OX=9031 GN=FAXC PE=3 SV=3 CANONICAL=E1C3J5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XMA3-1", "url": "https://www.uniprot.org/uniprotkb/E1C3J5/entry#A0A8V0XMA3-1", "sequence": { "sequence": "MTQTAVILCNKHIFKSSSFCRTSVFVHRKNYFDGKLSPQGKMPWIEYNHKKVSGTEFIIDFLEEKLGVNLNKNLGPRERAVSRAVTKMVEEHFYWTLAYCQWVENLHETQKMISVYGPLSDLLKWILCHLTKGIVKREMYGHGIGRFSEEEMYTLMEKDMRTLASLLGDKKYIMGPNLSTVDATVFGHLAQAMWTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTLYESEESSDASKTHSPLQDFSFYSRTETFDEEGNSISHTPDTDYTGHSLFDSDVDMDDYRDHEQCK", "length": 300, "header": "tr|A0A8V0XMA3-1|A0A8V0XMA3_CHICK Computationally mapped isoform of Failed axon connections homolog, metaxin like GST domain containing OS=Gallus gallus OX=9031 GN=FAXC PE=3 SV=1 CANONICAL=E1C3J5-1" }, "locus": { "chromosome": "3", "start_pos": 71231261, "end_pos": 71218325, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010137.1", "url": "https://www.ensembl.org/id/ENSGALT00010010137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005927.1", "url": "https://www.ensembl.org/id/ENSGALP00010005927.1" } ] } }, { "isoform_ac": "E1C3J5-1", "url": "https://www.uniprot.org/uniprotkb/E1C3J5/entry#E1C3J5-1", "sequence": { "sequence": "MLWGVGLAAPRSCVADLSRNRSLSLGWCAGPEEPPPALYGGELVAFPLAGAGAGGTMAALGSDSWWKKTLYLTGGALLAAAAYLLHELLAIRKEQEIDSKDAIILHQFSRPNNGVPSLSPFCLKMETYLRMADLPYQNYFDGKLSPQGKMPWIEYNHKKVSGTEFIIDFLEEKLGVNLNKNLGPRERAVSRAVTKMVEEHFYWTLAYCQWVENLHETQKMISVYGPLSDLLKWILCHLTKGIVKREMYGHGIGRFSEEEMYTLMEKDMRTLASLLGDKKYIMGPNLSTVDATVFGHLAQAMWTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTLYESEESSDASKTHSPLQDFSFYSRTETFDEEGNSISHTPDTDYTGHSLFDSDVDMDDYRDHEQCK", "length": 408, "header": "tr|E1C3J5-1|E1C3J5_CHICK Isoform 1 of Failed axon connections homolog, metaxin like GST domain containing OS=Gallus gallus OX=9031 GN=FAXC PE=3 SV=3 CANONICAL=E1C3J5-1" }, "locus": { "chromosome": "3", "start_pos": 71231261, "end_pos": 71215161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010010139.1", "url": "https://www.ensembl.org/id/ENSGALT00010010139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010005928.1", "url": "https://www.ensembl.org/id/ENSGALP00010005928.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428630", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428630", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C3J5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 408, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C3J5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C3J5" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3J5" }, { "id": "PF19333", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19333" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Failed axon connections homolog N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 109, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1C3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3J5" }, { "id": "PF17171", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17171" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metaxin glutathione S-transferase", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 327, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "E1C3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3J5" }, { "id": "PF17172", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17172" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin-like fold", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 212, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 285, "end_pos": 287 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3M8-1", "uniprot_ac": "E1C3M8", "uniprot_id": "E1C3M8_CHICK", "mass": { "chemical_mass": 58648.0, "monoisotopic_mass": 58648.0 }, "refseq": { "ac": "XP_024998116", "name": "potassium voltage-gated channel subfamily G member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998116" }, "gene_names": [ { "name": "KCNG1", "type": "recommended", "evidence": [ { "id": "E1C3M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ] }, { "name": "KCNG1", "type": "synonym", "evidence": [ { "id": "XP_024998116", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998116" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel modifier subfamily G member 1", "type": "synonym", "evidence": [ { "id": "E1C3M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3M8/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily G member 1", "type": "synonym", "evidence": [ { "id": "XP_024998116", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998116" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998116" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNG1", "url": "https://www.uniprot.org/uniprotkb/E1C3M8", "locus": { "chromosome": "20", "start_pos": 13714941, "end_pos": 13705097, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010014148", "url": "https://www.ensembl.org/id/ENSGALG00010014148" } ] } } ], "crossref": [ { "id": "E1C3M8", "url": "https://alphafold.ebi.ac.uk/entry/E1C3M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007980", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007980", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419347", "url": "https://www.ncbi.nlm.nih.gov/gene/419347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419347", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419347", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAFRNIL", "url": "https://omabrowser.org/oma/group/CAFRNIL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C3M8", "url": "https://www.orthodb.org/?gene=E1C3M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF88", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF88", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1296072", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_024998116", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998116", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3M8-1", "url": "https://www.uniprot.org/uniprotkb/E1C3M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLLPGENSDYDYSALSCASDASFNHTFFPETETLKGVFYQRAKLIHPEEDLLKGFHPDDRKHHIIINVGGIKYLLPWTTLDEFPLTRLGQLKFCNNFDDILNICDDYDVTCNEFFFDRNPGAFRTILTFLRVGKLRLLREMCALSFQEELLYWGIEEDNLDWCCKRRYLQKMEEFTEINEREDDLIENETTGETVEETKIGLCMKKLQDMVERPQSGLPGKVFACLSVLFVTITAVNLSISTMPDLREEEDKGECSQMCYNIFIVESVCVAWFSLEFLLRFIQAKNKFAFLRRPLTLIDIIAILPYYITLLVDTTSVGYKKPSSGSIYLDKVGLVLRILRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSQEFTSIPACYWWAVITMTTVGYGDMVPRSIPGQVVALSSILSGILLMAFPVTSIFHTFSRSYIELKQEQERIMYRRAQFLLKTKSQISNASQGSDILFPNISTDNRAMNDI", "length": 511, "header": "tr|E1C3M8-1|E1C3M8_CHICK Isoform 1 of Potassium voltage-gated channel modifier subfamily G member 1 OS=Gallus gallus OX=9031 GN=KCNG1 PE=4 SV=2 CANONICAL=E1C3M8-1" }, "isoforms": [ { "isoform_ac": "E1C3M8-1", "url": "https://www.uniprot.org/uniprotkb/E1C3M8/entry#E1C3M8-1", "sequence": { "sequence": "MTLLPGENSDYDYSALSCASDASFNHTFFPETETLKGVFYQRAKLIHPEEDLLKGFHPDDRKHHIIINVGGIKYLLPWTTLDEFPLTRLGQLKFCNNFDDILNICDDYDVTCNEFFFDRNPGAFRTILTFLRVGKLRLLREMCALSFQEELLYWGIEEDNLDWCCKRRYLQKMEEFTEINEREDDLIENETTGETVEETKIGLCMKKLQDMVERPQSGLPGKVFACLSVLFVTITAVNLSISTMPDLREEEDKGECSQMCYNIFIVESVCVAWFSLEFLLRFIQAKNKFAFLRRPLTLIDIIAILPYYITLLVDTTSVGYKKPSSGSIYLDKVGLVLRILRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSQEFTSIPACYWWAVITMTTVGYGDMVPRSIPGQVVALSSILSGILLMAFPVTSIFHTFSRSYIELKQEQERIMYRRAQFLLKTKSQISNASQGSDILFPNISTDNRAMNDI", "length": 511, "header": "tr|E1C3M8-1|E1C3M8_CHICK Isoform 1 of Potassium voltage-gated channel modifier subfamily G member 1 OS=Gallus gallus OX=9031 GN=KCNG1 PE=4 SV=2 CANONICAL=E1C3M8-1" }, "locus": { "chromosome": "20", "start_pos": 13713634, "end_pos": 13711598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010033985.1", "url": "https://www.ensembl.org/id/ENSGALT00010033985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010019972.1", "url": "https://www.ensembl.org/id/ENSGALP00010019972.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419347", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419347", "resource": "KEGG Pathway" }, { "id": "R-GGA-1296072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1296072", "resource": "Reactome", "description": "Voltage gated Potassium channels" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HEF9-1", "protein_name": "Potassium voltage-gated channel subfamily G member 1", "gene_name": "Kcng1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLRPQDDLHQGSSLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREGEEELLDSEDQDTEGPSASEGRLGRCMRKLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1C3M8", "url": "https://omabrowser.org/oma/group/E1C3M8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2BDX4-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG1", "gene_name": "Kcng1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLLPGDNSHYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLRPQDDLHQSCSLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREEEEEPLDSEDQESEGPSASEGRLSRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1C3M8", "url": "https://omabrowser.org/oma/group/E1C3M8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5GFZ3-1", "protein_name": "Potassium voltage-gated channel modifier subfamily G member 1", "gene_name": "KCNG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCASDASFHPAFFPQSQSLKGVFYRRAQRLRPQDEPRQGGQPEDRRRQIIINVGGIKYSLPWTTLEEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREDEDDPLDSEDRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSISTLPSLREEEEQGQCSQMCHNIFVVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERLMFRRTQFLLKTKSPLSSMSHDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1C3M8", "url": "https://omabrowser.org/oma/group/E1C3M8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4AD53-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG1", "gene_name": "Kcng1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLGPQDDLHQSISLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREDEEEALDSEDQESEGPSTSEGRLSRCMRRLRDMVEKPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1C3M8", "url": "https://omabrowser.org/oma/group/E1C3M8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BCM0-1", "protein_name": "Potassium voltage-gated channel modifier subfamily G member 1", "gene_name": "KCNG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCTSDASFHPAFFPQSQSLKGVFYRRAQRLRPQDEPRQGGQPEDRRRQIIINVGGIKYSLPWTTLEEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIQEFAETVEREDEEDALDSEDPDSEGPAEEEGRLGRCMRRLRDMVERPHSGLPGKVFAFLSVLFVTVTAVNLSISTLPSLREEEEQGRCSQMCRNIFIVESVCVGWFSLEFLLRLIQAPNKFVFLRSPLTLIDMVAILPYYVTLLVDGASAGRRKPGTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMAESPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRTQFLIKTKSQLSSMSHDSDILFGSASSDTRDNN", "length": 514 }, "evidence": [ { "id": "E1C3M8", "url": "https://omabrowser.org/oma/group/E1C3M8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9UIX4-1", "protein_name": "Voltage-gated potassium channel regulatory subunit KCNG1", "gene_name": "KCNG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN", "length": 513 }, "evidence": [ { "id": "E1C3M8", "url": "https://omabrowser.org/oma/group/E1C3M8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "potassium channel regulator activity", "id": "GO:0015459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "pmid": "" }, { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "E1C3M8", "url": "https://www.uniprot.org/uniprotkb/E1C3M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3V1-1", "uniprot_ac": "E1C3V1", "uniprot_id": "E1C3V1_CHICK", "mass": { "chemical_mass": 48812.0, "monoisotopic_mass": 48812.0 }, "refseq": { "ac": "XP_425217", "name": "BTB/POZ domain-containing protein KCTD16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425217" }, "gene_names": [ { "name": "KCTD16", "type": "recommended", "evidence": [ { "id": "E1C3V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3V1" } ] }, { "name": "KCTD16", "type": "synonym", "evidence": [ { "id": "XP_425217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425217" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD16", "type": "synonym", "evidence": [ { "id": "XP_425217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425217" } ] }, { "name": "Potassium channel tetramerization domain containing 16", "type": "synonym", "evidence": [ { "id": "E1C3V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3V1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052544.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_425217.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425217" } ] }, { "annotation": "Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.", "evidence": [ { "database": "UniProtKB", "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1#function" }, { "database": "UniProtKB", "id": "ARBA00057758", "url": "https://www.uniprot.org/uniprotkb/ARBA00057758#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD16", "url": "https://www.uniprot.org/uniprotkb/E1C3V1", "locus": { "chromosome": "13", "start_pos": 17211485, "end_pos": 17172898, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016505", "url": "https://www.ensembl.org/id/ENSGALG00010016505" } ] } } ], "crossref": [ { "id": "E1C3V1", "url": "https://alphafold.ebi.ac.uk/entry/E1C3V1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012322", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18398", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18398", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22219", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22219", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427644", "url": "https://www.ncbi.nlm.nih.gov/gene/427644", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427644", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427644", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHANVQT", "url": "https://omabrowser.org/oma/group/PHANVQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C3V1", "url": "https://www.orthodb.org/?gene=E1C3V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23110", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23110", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425217", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425217", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3V1-1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSGNCRTYLPAREQGSGLQSFPEVVELNVGGQVYFTRHSTLVGTPHSLLWKMFTPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDKQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDDSKQSPDDYCHSDYEEVSQGSDTRICPPPSLLPSDRKWGFITIGYRGSCTIGRESQADAKFRRVPRILVCGRIALVKEVFGESLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFVNQYTDDKVWSSYTEYVFYREPSRWASSHCDCCCKDGKGEKEGESGTSCNELSTSSCDSQSEGSSPQETVICGPVTRQPNIQTLDRPAKKGPVLLLQHSESRRKSDLLRTLTSGSRESTASKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL", "length": 427, "header": "tr|E1C3V1-1|E1C3V1_CHICK Isoform 1 of Potassium channel tetramerization domain containing 16 OS=Gallus gallus OX=9031 GN=KCTD16 PE=1 SV=1 CANONICAL=E1C3V1-1" }, "isoforms": [ { "isoform_ac": "E1C3V1-1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1/entry#E1C3V1-1", "sequence": { "sequence": "MALSGNCRTYLPAREQGSGLQSFPEVVELNVGGQVYFTRHSTLVGTPHSLLWKMFTPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDKQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDDSKQSPDDYCHSDYEEVSQGSDTRICPPPSLLPSDRKWGFITIGYRGSCTIGRESQADAKFRRVPRILVCGRIALVKEVFGESLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFVNQYTDDKVWSSYTEYVFYREPSRWASSHCDCCCKDGKGEKEGESGTSCNELSTSSCDSQSEGSSPQETVICGPVTRQPNIQTLDRPAKKGPVLLLQHSESRRKSDLLRTLTSGSRESTASKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL", "length": 427, "header": "tr|E1C3V1-1|E1C3V1_CHICK Isoform 1 of Potassium channel tetramerization domain containing 16 OS=Gallus gallus OX=9031 GN=KCTD16 PE=1 SV=1 CANONICAL=E1C3V1-1" }, "locus": { "chromosome": "13", "start_pos": 17209360, "end_pos": 17173968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039768.1", "url": "https://www.ensembl.org/id/ENSGALT00010039768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023013.1", "url": "https://www.ensembl.org/id/ENSGALP00010023013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427644", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427644", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BF73-1", "protein_name": "Potassium channel tetramerization domain containing 16", "gene_name": "KCTD16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALSGNCGRYYAREQGAAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRVFIDRDGFLFRYILDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLTPDEVKQSPDEFCHSDFEDASQGSDTRLCPPSSLLPADRKWGFITVGYRGSCTMGREGQTDAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFVNQYTDDKIWSSYTEYVFYREPSRWSSSHCDCCCKNGKGDKEGESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMRRKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL", "length": 428 }, "evidence": [ { "id": "E1C3V1", "url": "https://omabrowser.org/oma/group/E1C3V1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TER9-1", "protein_name": "Potassium channel tetramerization domain containing 16", "gene_name": "KCTD16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALSGNCSRYYSREQGAAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTMGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFRHLERAFDMLSECGFHMVACNSSVTASFVNQYTDDKIWSSYTEYVFYREPSRWSSSHCDCCCKNGKGDKEGESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMRRKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL", "length": 428 }, "evidence": [ { "id": "E1C3V1", "url": "https://omabrowser.org/oma/group/E1C3V1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5DTY9-1", "protein_name": "BTB/POZ domain-containing protein KCTD16", "gene_name": "Kctd16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALSGNCSRYYPRDQGAAVPNSFPEVIELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPERGRLKREAEYFQLPDLVKLLAPEDVKQSPDEFCHSDFEDASQGSDTRICPPSSLLPHDRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFVNQYTEDKIWSSYTEYVFYREPSRWSSSHCDCCCKNGKGDKGESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQSNIQTLDRPIKKGPVQLIQQSEMRRKSDLLRTLTSGSRESNISSKKKAAKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL", "length": 427 }, "evidence": [ { "id": "E1C3V1", "url": "https://omabrowser.org/oma/group/E1C3V1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q68DU8-1", "protein_name": "BTB/POZ domain-containing protein KCTD16", "gene_name": "KCTD16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKEGESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMRRKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQSELLRKYHL", "length": 428 }, "evidence": [ { "id": "E1C3V1", "url": "https://omabrowser.org/oma/group/E1C3V1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "E1C3V1", "url": "https://www.uniprot.org/uniprotkb/E1C3V1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C3V1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 427, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C3V1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C3V1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C3X5-1", "uniprot_ac": "E1C3X5", "uniprot_id": "E1C3X5_CHICK", "mass": { "chemical_mass": 10392.0, "monoisotopic_mass": 10392.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "E1C3X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3X5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C3X5", "url": "https://www.uniprot.org/uniprotkb/E1C3X5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E1C3X5", "locus": {} } ], "crossref": [ { "id": "E1C3X5", "url": "https://alphafold.ebi.ac.uk/entry/E1C3X5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "E1C3X5", "url": "https://www.uniprot.org/uniprotkb/E1C3X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C3X5-1", "url": "https://www.uniprot.org/uniprotkb/E1C3X5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCYSQCLPCRPCGPTPLASSCNEPCVRQCQNSNVIIEPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSSEGVPITSGGFDLSGFGSRYCGRRCFPC", "length": 101, "header": "tr|E1C3X5-1|E1C3X5_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=E1C3X5-1" }, "isoforms": [ { "isoform_ac": "E1C3X5-1", "url": "https://www.uniprot.org/uniprotkb/E1C3X5/entry#E1C3X5-1", "sequence": { "sequence": "MSCYSQCLPCRPCGPTPLASSCNEPCVRQCQNSNVIIEPSPVVVTLPGPILSSFPQNTAVGSSTSAAVGSILSSEGVPITSGGFDLSGFGSRYCGRRCFPC", "length": 101, "header": "tr|E1C3X5-1|E1C3X5_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=E1C3X5-1" }, "locus": { "chromosome": "27", "start_pos": 521088, "end_pos": 520786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010062748.1", "url": "https://www.ensembl.org/id/ENSGALT00010062748.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010038787.1", "url": "https://www.ensembl.org/id/ENSGALP00010038787.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": 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"domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 16 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232043" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C403", "url": "https://www.uniprot.org/uniprotkb/E1C403" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MLANA", "url": "https://www.uniprot.org/uniprotkb/E1C403", "locus": { "chromosome": "Z", "start_pos": 28235275, "end_pos": 28229918, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012923", "url": "https://www.ensembl.org/id/ENSGALG00010012923" } ] } } ], "crossref": [ { "id": "E1C403", "url": "https://alphafold.ebi.ac.uk/entry/E1C403", "database": "AlphaFoldDB", 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"categories": [ "Protein Classification" ] }, { "id": "PTHR15305:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15305:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14991", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14991", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001232043", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232043", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C403", "url": "https://www.uniprot.org/uniprotkb/E1C403", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C403-1", "url": "https://www.uniprot.org/uniprotkb/E1C403-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRRSHYEDGNFFRGKGRTYFTAEEALGIGIFILVLVLLLIFGCWFYKRRSGYKRLRSKGIGMDTIRTVVGEGARAACKTALQEYRNFNSVVPNAPPAYDKIAAEQSPPPYSP", "length": 113, "header": "tr|E1C403-1|E1C403_CHICK Isoform 1 of Melan-A OS=Gallus gallus OX=9031 GN=MLANA PE=4 SV=1 CANONICAL=E1C403-1" }, "isoforms": [ { "isoform_ac": "E1C403-1", "url": "https://www.uniprot.org/uniprotkb/E1C403/entry#E1C403-1", "sequence": { "sequence": "MPRRSHYEDGNFFRGKGRTYFTAEEALGIGIFILVLVLLLIFGCWFYKRRSGYKRLRSKGIGMDTIRTVVGEGARAACKTALQEYRNFNSVVPNAPPAYDKIAAEQSPPPYSP", "length": 113, "header": "tr|E1C403-1|E1C403_CHICK Isoform 1 of Melan-A OS=Gallus gallus OX=9031 GN=MLANA PE=4 SV=1 CANONICAL=E1C403-1" }, "locus": { "chromosome": "Z", "start_pos": 28235071, "end_pos": 28230945, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010031014.1", "url": "https://www.ensembl.org/id/ENSGALT00010031014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010018025.1", "url": "https://www.ensembl.org/id/ENSGALP00010018025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769648", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769648", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZWI9-1", "protein_name": "Melan-A", "gene_name": "Mlana", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPREEVHFGYPRKGHSHSYITAEEAAGIGILVVALGIALLIGCWYCRRRSGYRALTDKRRHAGTQNTSRERCLCESLDHQDSRLSSQEKNHQPVVPNAPPAYEKLSSDHSPPPYSP", "length": 116 }, "evidence": [ { "id": "E1C403", "url": "https://omabrowser.org/oma/group/E1C403/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MXK9-1", "protein_name": "Melan-A", "gene_name": "MLANA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPREEAHFFYGSPRKGHSHSYVTAEEAAGIGILIVILGILLLLSCWYCRRRSGYRSLKDKNIHAGTQSTLTGRCSHEGLGQQDSKLPFQENNCEPVIPNAPPAYEKLSAEQSPPPYSP", "length": 118 }, "evidence": [ { "id": "E1C403", "url": "https://omabrowser.org/oma/group/E1C403/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SMM1-1", "protein_name": "Melan-A", "gene_name": "MLANA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPREEAHFFYGSSKKGHGHSHITAEEAAGIGFLMVILGILLLISCWYCKRRSGYRSLKDKSIHDSTKSTLTRRCSHEGIGHQDSKLSFQENNCGPVVPNAPPAYEKFSTEQSPPPYFP", "length": 118 }, "evidence": [ { "id": "E1C403", "url": "https://omabrowser.org/oma/group/E1C403/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q16655-1", "protein_name": "Melanoma antigen recognized by T-cells 1", "gene_name": "MLANA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP", "length": 118 }, "evidence": [ { "id": "E1C403", "url": "https://omabrowser.org/oma/group/E1C403/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1C403", "url": "https://www.uniprot.org/uniprotkb/E1C403" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "E1C403", "url": "https://www.uniprot.org/uniprotkb/E1C403" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "E1C403", "url": "https://www.uniprot.org/uniprotkb/E1C403" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C403-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 113, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C403-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C403" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C483-1", "uniprot_ac": "E1C483", "uniprot_id": "E1C483_CHICK", "mass": { "chemical_mass": 29366.0, "monoisotopic_mass": 29366.0 }, "refseq": { "ac": "NP_001264476", "name": "acyl-CoA-binding domain-containing protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476" }, "gene_names": [ { "name": "ACBD6", "type": "recommended", "evidence": [ { "id": "E1C483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C483" } ] }, { "name": "ACBD6", "type": "synonym", "evidence": [ { "id": "NP_001264476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476" } ] }, { "name": "LHX4-AS1", "type": "synonym", "evidence": [ { "id": "NP_001264476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476" } ] } ], "protein_names": [ { "name": "Acyl-CoA-binding domain-containing protein 6", "type": "recommended", "evidence": [ { "id": "E1C483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C483/entry#names_and_taxonomy" } ] }, { "name": "LHX4 antisense RNA 1", "type": "synonym", "evidence": [ { "id": "NP_001264476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476" } ] }, { "name": "acyl-CoA-binding domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "NP_001264476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476" } ] }, { "name": "acyl-Coenzyme A binding domain containing 6", "type": "synonym", "evidence": [ { "id": "NP_001264476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01131103.1, HAEK01001117.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Apr 11, 2013 this sequence version replaced XP_422259.3. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C483", "url": "https://www.uniprot.org/uniprotkb/E1C483" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACBD6", "url": "https://www.uniprot.org/uniprotkb/E1C483", "locus": { "chromosome": "8", "start_pos": 5976749, "end_pos": 5909672, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010849", "url": "https://www.ensembl.org/id/ENSGALG00010010849" } ] } } ], "crossref": [ { "id": "E1C483", "url": "https://alphafold.ebi.ac.uk/entry/E1C483", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003924", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003924", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424416", "url": "https://www.ncbi.nlm.nih.gov/gene/424416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424416", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARSKWQA", "url": "https://omabrowser.org/oma/group/ARSKWQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C483", "url": "https://www.orthodb.org/?gene=E1C483", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24119:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24119:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-77289", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C483", "url": "https://www.uniprot.org/uniprotkb/E1C483", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C483-1", "url": "https://www.uniprot.org/uniprotkb/E1C483-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPPLAAGSGGEGSSGSAGPDPSDRQLSALFEQAAERLPALLPNASKEQLLYLYARYKQVKFGTCNTPKPGFFDFEGKQKWEAWKALGDTSPHQAMQEYVATVKKLDPSWNPQTTEKRGKESKTAFGGPVVSSLYQEETIREEDKNIFDYCRENNIDYVTKAIQSKKVDVNVADEEGRALLHWACDRGHKELVSVLLQHAADVNSQDGEGQTALHYASACEFSDIVELLLQSGADPTLRDKEGCLPEEVTDCKAITSALQRHTAGKV", "length": 268, "header": "tr|E1C483-1|E1C483_CHICK Isoform 1 of Acyl-CoA-binding domain-containing protein 6 OS=Gallus gallus OX=9031 GN=ACBD6 PE=1 SV=3 CANONICAL=E1C483-1" }, "isoforms": [ { "isoform_ac": "E1C483-1", "url": "https://www.uniprot.org/uniprotkb/E1C483/entry#E1C483-1", "sequence": { "sequence": "MASPPLAAGSGGEGSSGSAGPDPSDRQLSALFEQAAERLPALLPNASKEQLLYLYARYKQVKFGTCNTPKPGFFDFEGKQKWEAWKALGDTSPHQAMQEYVATVKKLDPSWNPQTTEKRGKESKTAFGGPVVSSLYQEETIREEDKNIFDYCRENNIDYVTKAIQSKKVDVNVADEEGRALLHWACDRGHKELVSVLLQHAADVNSQDGEGQTALHYASACEFSDIVELLLQSGADPTLRDKEGCLPEEVTDCKAITSALQRHTAGKV", "length": 268, "header": "tr|E1C483-1|E1C483_CHICK Isoform 1 of Acyl-CoA-binding domain-containing protein 6 OS=Gallus gallus OX=9031 GN=ACBD6 PE=1 SV=3 CANONICAL=E1C483-1" }, "locus": { "chromosome": "8", "start_pos": 5976476, "end_pos": 5909725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025970.1", "url": "https://www.ensembl.org/id/ENSGALT00010025970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014631.1", "url": "https://www.ensembl.org/id/ENSGALP00010014631.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424416", "resource": "KEGG Pathway" }, { "id": "R-GGA-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "G3H7I4-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbd6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATPFLPAGATTGDSGGELSSGDDSGEMESSQNPETEASRNLDELFEKAAAHVQGLVHVASREQLLYLYARYKQVKVGNCNIPKPNFFDFEGKQKWEAWKALGDSSPRQAMQEYIAAVKKLDPGWKPQVSEKKGKEANNGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHVTKAIKSKSVEVNVKDEEGRAMLHWACDRGHKELVTVLLQYEADINCQDNEGQTALHYAAACEFLDIVELLLQSGADPTIRDQDDCLPEEVTGCKAVSLVLQLHRTNKA", "length": 282 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3N0L6-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "ACBD6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASSFLPSGATTGDSGGELSSGDDSGDVESLQSPKIEASRSLPELFEKAAEHLQGLVQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPSWNPQSPEKKGKEANTGFGGPVVSSLYHEEIIREEDKDIFDYCRENNIDHITKVIKTKNMDVNMKDEEGRTLLHWACDRGHKELVTVLLQYRADINCQDNEGQTALHYAAACEFLDIVELLLQSGADPMLRDQDGCLPEEVTGCKAVTLMLQQHTTGKA", "length": 282 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54GC8-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6 homolog", "gene_name": "acbd6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTDAQIENKFKLAVDYITNNSGKLSNIKNEEQLYLYCNYKQATIGDCNTKAPPFYDYIGKSKWNSWNSLKGVEKIVAMNSYISLVNALSPGWDSNIKVERATQSVFLNDEEFKELEKKEKEEKEELKKLEEENGGEIEKPKSKWMGPVLSKFSLVDDETLEKLEKNTKQDLGYWVSVNDIERVKKEIENDKNIINEVDEDGRTALIWACDRGYFEIAKLLIENGSNVNVQDGEGMTPLHYAVVCDQFEICKLLLSQSSIDKSIKDNSDSIPSDFIDSSTSENIKSLFK", "length": 288 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RJK8-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbd6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATPFLPAGATTGDSGGELSSGDDSGDLESFQTPEAEATRSLAELFEKAAAHVQGLVQVASREQLLYLYARYKQVKVGNCNIPKPNFFDFEGKQKWEAWKALGDSSPSQAMQEYIAAVKKLDPGWNPQVSEKKGKEGSSGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKTVDVNMTDEEGRALLHWACDRGHKELVKVLLQCEAGINCQDNEGQTALHYAAACEFSDIVELLLQSGADPTLRDQDGCLPEEVTGCKAVSLVLQLHRAGKA", "length": 282 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BR61-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "ACBD6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETSCLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGNCNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVVKKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIREEDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALLHWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVLQRHTTGKA", "length": 282 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D061-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbd6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPFLPSGATTGDSGGELSSGDDSGDMESFQTPEAEGTRSLAELFEKAAAHVQGLVQVASREQLLYLYARFKQVKVGNCNTPKPNFFDFEGKQKWEAWKALGDSSPSQAMQEYIAAVKKLDPGWNPQVSEKKGKEGSSGFGGPVVSSLYHEETIREEDKNIFDYCRENNIDHIAKAIKSKAADVNMTDEEGRALLHWACDRGHKELVKVLLQYEAGINCQDNEGQTALHYAAACEFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKAVSLLLQRHRASKA", "length": 282 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SM23-1", "protein_name": "Acyl-CoA-binding domain-containing protein 1", "gene_name": "ACBP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADWYQLAQSIIFGLIFAYLLAKLISILLAFKDENLSLTRNHTTQSEYENLRKVETLTGISGETDSLIAEQGSLRGDEDESDDDDWEGVESTELDEAFSAATAFVAAAASDRLSQKVSNELQLQLYGLYKIATEGPCTAPQPSALKMTARAKWQAWQKLGAMPPEEAMEKYIDLVTQLYPAWVEGGSKRRNRSGEAAGPMGPVFSSLVYEEESDNELKIDAIHAFAREGEVENLLKCIENGIPVNARDSEGRTPLHWAIDRGHLNVAEALVDKNADVNAKDNEGQTSLHYAVVCEREALAEFLVKQKADTTIKDEDGNSPLDLCESEWSWMREKKDSN", "length": 338 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VRG6-1", "protein_name": "Acyl-CoA-binding domain-containing protein 6", "gene_name": "Acbp-Ank", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSDTDTVDELFHLATEHVAKQSNSIGSADLLIFYGYYKQATNGPCKEQSPGLLQLQAKSKWQAWRNLGTMSQSAARQAYVQKLQELQPNWRSRRNPGWVVHSIESVPLEDQRLDSEKTLFDHVKENNLDRLRELLQPSDLVKLDEHGMALIHWATDRNAVEIIQFLVRSGASVNQRDAEQQTPLHYAASCGHLEALQCLLELHASLELRDSDGQTCYDVADDEQICQVLQTERERLAGSAS", "length": 243 }, "evidence": [ { "id": "E1C483", "url": "https://omabrowser.org/oma/group/E1C483/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C483", "url": "https://www.uniprot.org/uniprotkb/E1C483" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C483", "url": "https://www.uniprot.org/uniprotkb/E1C483" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "E1C483", "url": "https://www.uniprot.org/uniprotkb/E1C483" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C483-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 268, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C483-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C483" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C4J7-1", "uniprot_ac": "E1C4J7", "uniprot_id": "E1C4J7_CHICK", "mass": { "chemical_mass": 51403.0, "monoisotopic_mass": 51403.0 }, "refseq": { "ac": "XP_004948635", "name": "F-box only protein 47", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948635" }, "gene_names": [ { "name": "FBXO47", "type": "recommended", "evidence": [ { "id": "E1C4J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4J7" } ] }, { "name": "FBXO47", "type": "synonym", "evidence": [ { "id": "XP_004948635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948635" } ] } ], "protein_names": [ { "name": "F-box only protein 47", "type": "synonym", "evidence": [ { "id": "XP_004948635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948635" } ] }, { "name": "F-box protein 47", "type": "synonym", "evidence": [ { "id": "E1C4J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4J7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948635" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C4J7", "url": "https://www.uniprot.org/uniprotkb/E1C4J7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO47", "url": "https://www.uniprot.org/uniprotkb/E1C4J7", "locus": { "chromosome": "27", "start_pos": 4060696, "end_pos": 4069233, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021696", "url": "https://www.ensembl.org/id/ENSGALG00010021696" } ] } } ], "crossref": [ { "id": "E1C4J7", "url": "https://alphafold.ebi.ac.uk/entry/E1C4J7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000019738", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000019738", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771854", "url": "https://www.ncbi.nlm.nih.gov/gene/771854", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771854", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771854", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFACVTM", "url": "https://omabrowser.org/oma/group/AFACVTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C4J7", "url": "https://www.orthodb.org/?gene=E1C4J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34098:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34098:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948635", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C4J7", "url": "https://www.uniprot.org/uniprotkb/E1C4J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C4J7-1", "url": "https://www.uniprot.org/uniprotkb/E1C4J7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSTARTSCTSGPNQKHRGSNHHSRQSCNTVDTDSQSLSTLGYFKTLPLEIFQMLLSYLSVKDISVLSMVSKAISNRLINYISTPSGNRRLLLQDFHNIKLSGKREGSYIIEHYKSLGLLLKRCTLLLPTKDRLKYIHKVLSEVSCFKLNGCPSPLHCVGLQCYGVFLQILIAGWDELECHRVFNFLCELSNLPRKVQAVVSCKPGSARKLELRIRLFCRSVLLNHWIHRSDSAFWLTRILKPWPMVNQARLLYIIFGPVSSLDGHVVWQKMIEGPTDETSLKGLADAIKLLYDPEAREWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAVELARLVVFLALVCEKDLYCMDWAVKMMQKVCKVFSTPGERNIFLQSVENAFAHMVMDMLQAVLAGNRDQEDISFLNLFHLVNAQANFHKEILYLTMRSGSNTI", "length": 453, "header": "tr|E1C4J7-1|E1C4J7_CHICK Isoform 1 of F-box protein 47 OS=Gallus gallus OX=9031 GN=FBXO47 PE=4 SV=4 CANONICAL=E1C4J7-1" }, "isoforms": [ { "isoform_ac": "E1C4J7-1", "url": "https://www.uniprot.org/uniprotkb/E1C4J7/entry#E1C4J7-1", "sequence": { "sequence": "MTSTARTSCTSGPNQKHRGSNHHSRQSCNTVDTDSQSLSTLGYFKTLPLEIFQMLLSYLSVKDISVLSMVSKAISNRLINYISTPSGNRRLLLQDFHNIKLSGKREGSYIIEHYKSLGLLLKRCTLLLPTKDRLKYIHKVLSEVSCFKLNGCPSPLHCVGLQCYGVFLQILIAGWDELECHRVFNFLCELSNLPRKVQAVVSCKPGSARKLELRIRLFCRSVLLNHWIHRSDSAFWLTRILKPWPMVNQARLLYIIFGPVSSLDGHVVWQKMIEGPTDETSLKGLADAIKLLYDPEAREWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAVELARLVVFLALVCEKDLYCMDWAVKMMQKVCKVFSTPGERNIFLQSVENAFAHMVMDMLQAVLAGNRDQEDISFLNLFHLVNAQANFHKEILYLTMRSGSNTI", "length": 453, "header": "tr|E1C4J7-1|E1C4J7_CHICK Isoform 1 of F-box protein 47 OS=Gallus gallus OX=9031 GN=FBXO47 PE=4 SV=4 CANONICAL=E1C4J7-1" }, "locus": { "chromosome": "27", "start_pos": 4068215, "end_pos": 4061408, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052715.1", "url": "https://www.ensembl.org/id/ENSGALT00010052715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031621.1", "url": "https://www.ensembl.org/id/ENSGALP00010031621.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771854", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771854", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287APT5-1", "protein_name": "F-box protein 47", "gene_name": "FBXO47", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRVNSSFTLIPNQKYRRSNRRSSYFSNNLASDSQPLSTLGNFKALPLEIFQIILRYLSVKDISMLSMVSKTISQHIINYISTSSGSKRLLLPDFHNLELPDRKQESAILEYYRSLGLLFKRCTLLLPTKERLKYIHKILAEVSCFKFSGCAAPLQCLGLPCYGMFLQTLTAGWDELECHRVFNFLCELTNLPRKMQTVVCSKPGSARKLELRIRLFCRRVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPVSPQDGQVVWQRMIEGPTDEPSLKGLADAIKLLYDTGTKEWTADDIISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAIELARLIVFLALVCEKELYCMDWAVKMMQKVCKVFSTPVERNNFLQSVANAFACVTMEMLQSVMSGDRDEDDRSFLNLYHLVQAQANFHKEVLSLTVNTLST", "length": 451 }, "evidence": [ { "id": "E1C4J7", "url": "https://omabrowser.org/oma/group/E1C4J7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LX24-1", "protein_name": "F-box protein 47", "gene_name": "Fbxo47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRVNTTFTLIPSSKCRRLNHQSSDFCNTLDSDPQLLSTLGNFKVLPLEILHIILRYLSVKDIGMLSMVSKTVSQHIINYISTSSGSRRLLLQNFHDLDLPGTKEETALLEHYRALGLLFKRCTLLLPTKERLKYIQKILSEVPCFKFSGCSAPLQCLGLSCYGMFLQTLTAGWDELECHRVYNFLCEQTNLSRKMQTVVCNKPGSARKLELRVRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPTSPHDGQVIWQEMIEGPTDESSLKGLANAIKLLYDTGAKGWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAIELARLIVFLALVCEKELYCMDWTVRMMQKVCKVFNTATERKSFLQSVANAFACVTMEMLQPVMSGERDDDDRGFLNLFHLLHAQANFHKEVLYLTMNAVSS", "length": 451 }, "evidence": [ { "id": "E1C4J7", "url": "https://omabrowser.org/oma/group/E1C4J7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2A6H3-1", "protein_name": "F-box only protein 47", "gene_name": "Fbxo47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRVNTSFTLIPKQKCRRSNHHSSYFCNTLDSDPQLLSTLGNFKVLPLEILHIILRYLSVKDIGMLSMVSKTVSQHIINYISTSSGSRRLLLQNFHDLDLPGTKEETALLEHYRALGLLFKRCTLLLPTKERLKYIHKILSEVSCFKFSGCSVPLQCLGLSCYGMFLQTLTAGWDELECHRVYNFLCELTNLSRKMQTVVCNKPGSARKLELRVRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPTSPHDGQVIWQEMIEGPTDESSLKGLANAIKLLYDTGAKGWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRAVELARLVVFLALVCEKELYCMDWTVRMMQKVCKVFSTAAERKSFLQSIANAFACVTMEMLQPVMSGDRDDDDRGFLNLFHLLHAQANFHKEVLYLTMNAISS", "length": 451 }, "evidence": [ { "id": "E1C4J7", "url": "https://omabrowser.org/oma/group/E1C4J7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6RFM1-1", "protein_name": "F-box protein 47", "gene_name": "FBXO47", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSRVNTSFTLIPNQKYRRSSRRSSCFSNTFDSDSQPLSTLGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHDLELPDREDTAIVEHYRSLGLLFKRCTLLLPTKERLKYIHKILADVSCFKFNGCAAPLQCVGLLCYGIFLQTLTAGWDELECHRVYNFLCELTHLSRKMQTVVCSKPGSARKLELRIRLFCRNVLLDHWTHRSDSAFWLTCILKPWPMVNQARLLYIIFGPISPQDGQVVWQKMIEGPTDESCLKGLAEAIKLLYDTGTKEWTADDVISLVDELSVVPREWLLENNARLLILSGNNICFTFMASKAVNGRTIELAKLIVFLALVSEKELYCMDWAVKMMQKVCKVFSTPVERNNFLQSVADAFACAIMEMLQLVMSGDGDDDDRSFMNLFHLVQAQASFHKEVLYLTMNVLPS", "length": 450 }, "evidence": [ { "id": "E1C4J7", "url": "https://omabrowser.org/oma/group/E1C4J7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5MNV8-1", "protein_name": "F-box only protein 47", "gene_name": "FBXO47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRINTNFTLIPNQKLRRSNRQTSCYSKTLGSGFQPISTFGNFKALPLEIFQIILKYLSVKDISMLSMVSKTVSQHIINYISTSSGSKRLLLQDFHNLELPDRRQDSAILEHYRSLGLLFKRCTLLLPTKERLKYIHKILTEVSCFKFNGCAAPMQCLGLTCYGMFLQTLTAGWDELECHRVYNFLCELTNLCRKIQMAVCSKPGSAQKLELRIRLFCRNVLLDHWTHRSDSAFWLTRILKPWPMVNQARLLYIIFGPISPQDGQVVWQEMIEEPTDEFSLKGLADAIKLLYDASTKEWTADDVISLVDELSVVPREWLLENNARLLMLSGNNICFSFMASKAVNGRTIELARLVVFLALVCEKELYCMDWTVKMMQKVCKVFSTPVERKNFLQNVANAFACVIMEMLQSIMSGDRDEDDRSFLNLFHLVHAQANFHKEVLYLTMNTPLST", "length": 452 }, "evidence": [ { "id": "E1C4J7", "url": "https://omabrowser.org/oma/group/E1C4J7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C4J7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 453, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C4J7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C4J7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C4N0-1", "uniprot_ac": "E1C4N0", "uniprot_id": "E1C4N0_CHICK", "mass": { "chemical_mass": 18910.0, "monoisotopic_mass": 18910.0 }, "refseq": { "ac": "NP_001244226", "name": "small ribosomal subunit protein eS10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244226" }, "gene_names": [ { "name": "RPS10", "type": "recommended", "evidence": [ { "id": "E1C4N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4N0" } ] }, { "name": "RPS10", "type": "synonym", "evidence": [ { "id": "NP_001244226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244226" } ] } ], "protein_names": [ { "name": "Ribosomal protein S10", "type": "synonym", "evidence": [ { "id": "E1C4N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4N0/entry#names_and_taxonomy" } ] }, { "name": "small ribosomal subunit protein eS10", "type": "synonym", "evidence": [ { "id": "NP_001244226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244226" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CN236490.1, HAEL01014645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000356.1. On Mar 29, 2012 this sequence version replaced XP_418029.2. Sequence Note: This RefSeq record was created from transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001244226", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244226" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C4N0", "url": "https://www.uniprot.org/uniprotkb/E1C4N0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPS10", "url": "https://www.uniprot.org/uniprotkb/E1C4N0", "locus": { "chromosome": "26", "start_pos": 4422745, "end_pos": 4417262, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010026148", "url": "https://www.ensembl.org/id/ENSGALG00010026148" } ] } } ], "crossref": [ { "id": "E1C4N0", "url": "https://alphafold.ebi.ac.uk/entry/E1C4N0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002813", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002813", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419904", "url": "https://www.ncbi.nlm.nih.gov/gene/419904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8Q7Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q7Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8Q87&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR005326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419904", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRRRDQE", "url": "https://omabrowser.org/oma/group/YRRRDQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C4N0", "url": "https://www.orthodb.org/?gene=E1C4N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12146", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12146", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12146:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12146:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008q7z", "url": "https://www.rcsb.org/structure/pdb_00008q7z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008q87", "url": "https://www.rcsb.org/structure/pdb_00008q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q7Z", "url": "https://www.rcsb.org/structure/8Q7Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8Q87", "url": "https://www.rcsb.org/structure/8Q87", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF03501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72702", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954714", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9954716", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001244226", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C4N0", "url": "https://www.uniprot.org/uniprotkb/E1C4N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C4N0-1", "url": "https://www.uniprot.org/uniprotkb/E1C4N0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELVDKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSRPETGRPRPKGLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGAATEFQFRGGFGRGRGQPPQ", "length": 165, "header": "tr|E1C4N0-1|E1C4N0_CHICK Isoform 1 of Ribosomal protein S10 OS=Gallus gallus OX=9031 GN=RPS10 PE=1 SV=2 CANONICAL=E1C4N0-1" }, "isoforms": [ { "isoform_ac": "E1C4N0-1", "url": "https://www.uniprot.org/uniprotkb/E1C4N0/entry#E1C4N0-1", "sequence": { "sequence": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELVDKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSRPETGRPRPKGLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGAATEFQFRGGFGRGRGQPPQ", "length": 165, "header": "tr|E1C4N0-1|E1C4N0_CHICK Isoform 1 of Ribosomal protein S10 OS=Gallus gallus OX=9031 GN=RPS10 PE=1 SV=2 CANONICAL=E1C4N0-1" }, "locus": { "chromosome": "26", "start_pos": 4422701, "end_pos": 4418190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010063689.1", "url": "https://www.ensembl.org/id/ENSGALT00010063689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010039306.1", "url": "https://www.ensembl.org/id/ENSGALP00010039306.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.", "journal": "FEBS Lett.", "date": "2024", "authors": "Nurullina Liliia, Terrosu Salvatore, Myasnikov Alexander G, Jenner Lasse Bohl, Yusupov Marat", "evidence": [ { "database": "UniProtKB", "id": "E1C4N0", "url": "https://www.uniprot.org/uniprotkb/E1C4N0" } ], "reference": [ { "type": "PubMed", "id": "38395592", "url": "https://glygen.org/publication/PubMed/38395592" } ] } ], "pathway": [ { "id": "gga:419904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419904", "resource": "KEGG Pathway" }, { "id": "R-GGA-1799339", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-72695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72695", "resource": "Reactome", "description": "Formation of the ternary complex, and subsequently, the 43S complex" }, { "id": "R-GGA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" }, { "id": "R-GGA-72706", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-GGA-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-GGA-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-GGA-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-GGA-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IM84-1", "protein_name": "Small ribosomal subunit protein eS10", "gene_name": "Rps10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSRPETGRPRPKGPEGERPARFTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "length": 165 }, "evidence": [ { "id": "E1C4N0", "url": "https://omabrowser.org/oma/group/E1C4N0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O77082-1", "protein_name": "Small ribosomal subunit protein eS10", "gene_name": "rps10", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPLIPTENKLAIYRYLFQEGVLVAPKDFHLAKHPQIETVSNLDVLQILRSFKSRKFVTETFNWQYYYWVLTEEGIKYLRTYLQVPESVVPATMKKQASRPSTYTRSEETKRTGASGDFDPSFNRGDRRQGGDRRGGMGRGQYRTERSAPAPQQN", "length": 154 }, "evidence": [ { "id": "E1C4N0", "url": "https://omabrowser.org/oma/group/E1C4N0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P46783-1", "protein_name": "Small ribosomal subunit protein eS10", "gene_name": "RPS10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSRPETGRPRPKGLEGERPARLTRGEADRDTYRRSAVPPGADKKAEAGAGSATEFQFRGGFGRGRGQPPQ", "length": 165 }, "evidence": [ { "id": "E1C4N0", "url": "https://omabrowser.org/oma/group/E1C4N0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P63325-1", "protein_name": "Small ribosomal subunit protein eS10", "gene_name": "Rps10", 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"https://www.uniprot.org/uniprotkb/E1C4N0" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "E1C4N0", "url": "https://www.uniprot.org/uniprotkb/E1C4N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C4N0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 165, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C4N0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C4N0" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C4N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C4N0" }, { "id": "PF03501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Plectin/eS10 N-terminal", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 97, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E1C599-1", "uniprot_ac": "E1C599", "uniprot_id": "E1C599_CHICK", "mass": { "chemical_mass": 35670.0, "monoisotopic_mass": 35670.0 }, "refseq": { "ac": "XP_417251", "name": "dnaJ homolog subfamily B member 13 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417251" }, "gene_names": [ { "name": "DNAJB13", "type": "recommended", "evidence": [ { "id": "E1C599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ] }, { "name": "DNAJB13", "type": "synonym", "evidence": [ { "id": "XP_417251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417251" } ] } ], "protein_names": [ { "name": "DnaJ homolog subfamily B member 13", "type": "recommended", "evidence": [ { "id": "E1C599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C599/entry#names_and_taxonomy" } ] }, { "name": "Testis and spermatogenesis cell-related protein 6", "type": "synonym", "evidence": [ { "id": "E1C599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C599/entry#names_and_taxonomy" } ] }, { "name": "Testis spermatocyte apoptosis-related gene 6 protein", "type": "synonym", "evidence": [ { "id": "E1C599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C599/entry#names_and_taxonomy" } ] }, { "name": "Testis spermatogenesis apoptosis-related gene 3 protein", "type": "synonym", "evidence": [ { "id": "E1C599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C599/entry#names_and_taxonomy" } ] }, { "name": "Testis spermatogenesis apoptosis-related gene 6 protein", "type": "synonym", "evidence": [ { "id": "E1C599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C599/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily B member 13 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_417251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417251" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_417251.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417251" } ] }, { "annotation": "Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia.", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599#function" }, { "database": "UniProtKB", "id": "ARBA00056649", "url": "https://www.uniprot.org/uniprotkb/ARBA00056649#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJB13", "url": "https://www.uniprot.org/uniprotkb/E1C599", "locus": { "chromosome": "1", "start_pos": 194842750, "end_pos": 194850786, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010002523", "url": "https://www.ensembl.org/id/ENSGALG00010002523" } ] } } ], "crossref": [ { "id": "E1C599", "url": "https://alphafold.ebi.ac.uk/entry/E1C599", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000017317", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000017317", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419060", "url": "https://www.ncbi.nlm.nih.gov/gene/419060", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SSKYVYH", "url": "https://omabrowser.org/oma/group/SSKYVYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0XAB6", "url": "https://www.orthodb.org/?gene=A0A8V0XAB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C599", "url": "https://www.orthodb.org/?gene=E1C599", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24078:SF519", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24078:SF519", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1C599", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1C599", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_417251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417251", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0XAB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0XAB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C599-1", "url": "https://www.uniprot.org/uniprotkb/E1C599-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQDYYAVLELGRNATDADIKKAYRLLALENHPQKCKEPLAQERFRLLAEAYDVLSDPVRRGIYDRFGEEGLKGGIPVGSDGEDAWTAGYVFHNNPDKVFKEFFGGHNPFAEFFTKDGLEVTLPFGGLHGRGVMKQDPPMVWDLHVSLEDLFFGCTKKMKISHRVMNEDGQTSTIRDKILIIDVQPGWKQGTRVTFEKEGDQGPNIIPSDITFVVQEKPHPRFKRTNDDLIYVASIPLGKALIGCTVDVRTLDGRLLSIPINDIVHPTYCKVVPGEGMPLLEDPRRRGDLLIHFNICFPKRLTPDKKVLLRRALLS", "length": 316, "header": "tr|E1C599-1|E1C599_CHICK Isoform 1 of DnaJ homolog subfamily B member 13 OS=Gallus gallus OX=9031 GN=DNAJB13 PE=1 SV=3 CANONICAL=E1C599-1" }, "isoforms": [ { "isoform_ac": "A0A8V0XAB6-1", "url": "https://www.uniprot.org/uniprotkb/E1C599/entry#A0A8V0XAB6-1", "sequence": { "sequence": "MGQDYYAVLELGRNATDADIKKAYRLLALENHPQKCKEPLAQERFRLLAEAYDVLSDPVRRGIYDRFGEEGLKGGIPVGSDGEDAWTAGYVFHNNPDKVFKEFFGGHNPFAEFFTKDGLEVTLPFGGLHGRGVMKQDPPMVWDLHVSLEDLFFGCTKKMKISHRVMNEDGQTSTIRDKILIIDVQPGWKQGTRVTFEKEGDQVSYFCHVPAVGAQDCCSATAPVGTPGCAVPLALTQGSDTFLWAVAALLCSESERKERSPFCLHLGVKIMERGAVLSALAFAELTLVSFGLTGDFDKTHCWLFCPK", "length": 307, "header": "tr|A0A8V0XAB6-1|A0A8V0XAB6_CHICK Computationally mapped isoform of DnaJ heat shock protein family (Hsp40) member B13 OS=Gallus gallus OX=9031 GN=DNAJB13 PE=4 SV=1 CANONICAL=E1C599-1" }, "locus": { "chromosome": "1", "start_pos": 194850769, "end_pos": 194847967, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005791.1", "url": "https://www.ensembl.org/id/ENSGALT00010005791.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003596.1", "url": "https://www.ensembl.org/id/ENSGALP00010003596.1" } ] } }, { "isoform_ac": "E1C599-1", "url": "https://www.uniprot.org/uniprotkb/E1C599/entry#E1C599-1", "sequence": { "sequence": "MGQDYYAVLELGRNATDADIKKAYRLLALENHPQKCKEPLAQERFRLLAEAYDVLSDPVRRGIYDRFGEEGLKGGIPVGSDGEDAWTAGYVFHNNPDKVFKEFFGGHNPFAEFFTKDGLEVTLPFGGLHGRGVMKQDPPMVWDLHVSLEDLFFGCTKKMKISHRVMNEDGQTSTIRDKILIIDVQPGWKQGTRVTFEKEGDQGPNIIPSDITFVVQEKPHPRFKRTNDDLIYVASIPLGKALIGCTVDVRTLDGRLLSIPINDIVHPTYCKVVPGEGMPLLEDPRRRGDLLIHFNICFPKRLTPDKKVLLRRALLS", "length": 316, "header": "tr|E1C599-1|E1C599_CHICK Isoform 1 of DnaJ homolog subfamily B member 13 OS=Gallus gallus OX=9031 GN=DNAJB13 PE=1 SV=3 CANONICAL=E1C599-1" }, "locus": { "chromosome": "1", "start_pos": 194850769, "end_pos": 194846830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010005795.1", "url": "https://www.ensembl.org/id/ENSGALT00010005795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010003599.1", "url": "https://www.ensembl.org/id/ENSGALP00010003599.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FLR1-1", "protein_name": "DnaJ homolog subfamily B member 13 isoform X1", "gene_name": "Dnajb13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGVDYYAVLQVTRNSEDAQIKKAYRKLALKNHPLKSNEPSAPEIFKQIAEAYDVLSDQTSRQQVARAILAHHRPELSDCPPASPVTHTPDPSSRSHVSTAVKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGNPDKVFHEFFGGDNPFSEFFDAEGNDIDLNFGGLRGRGVQKQDPPIERDLYLSLEDLFFGCTKKIKISRRVLNEDKYSSTIKDKILTIDVRPGWRQGTRITFEKEGDQGPNIIPADIIFVVKEKLHPRFRRERDNLLFVYPIPLGKALTCCTVEVRTLDDRLLNIPINDIVHWKKEKTESLDNQSLSWSPSLERDPKRRKEGMNLERENTSHGGGTSSSCFYHRPSNPPHGLSQRKLTGPGEEPHSCVPKSKTPEYLAH", "length": 395 }, "evidence": [ { "id": "E1C599", "url": "https://omabrowser.org/oma/group/E1C599/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SUR7-1", "protein_name": "DnaJ homolog subfamily B member 13", "gene_name": "DNAJB13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQDYYAVLQITRNSEDAQIKNAYRKLALKNHPLRSIEPSSAETFRQIAEAYDVLSDPVKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGNPEKVFHEFFGGDNPFNEFFDAEGNEVDLNFGGLRGRGVKKQDPPIERDLYLSLEDLFFGCTKKIKISRRVLNEDGFSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRRENDDLFFVNAIPLGKALTCCTVEVKTLDDRLLNIPINDIVHPKYFKKVPGEGMPLPEEPARKGDLFIFFDIQFPTRLTPQKKQMLRQALLT", "length": 316 }, "evidence": [ { "id": "E1C599", "url": "https://omabrowser.org/oma/group/E1C599/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4JY55-1", "protein_name": "DNAJ heat shock family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGLDYYDILKVNRNATEDDLKKSYRKLAMKWHPDKNPNTKTEAEAKFKQISEAYEAKYEVMFQVLSDPQKRAVYDQYGEEGLSDMPPPGSTGNNGRAGGFNPRNAEDIFAEFFGSSPFGFGSAGGPGRSMRFQSDGGGGMFGGFGGGNNGSENNIFRTYSEGTPAPKKPPPVESKLPCSLEELYSGSTRKMKISRSIVDANGRQAQETEILTIVVKPGWKKGTKIKFPDKGNEQVNQLPADLVFVIDEKPHDLFTRDGNDLITSRRVTLAEAIGGTTVNINTLDGRNLPVGVAEIVSPGYEFVVPGEGMPIAKEPRNKGDLKIKFDVQFPARLTTEQKSALKRVLAG", "length": 347 }, "evidence": [ { "id": "E1C599", "url": "https://omabrowser.org/oma/group/E1C599/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P59910-1", "protein_name": "DnaJ homolog subfamily B member 13", "gene_name": "DNAJB13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQDYYSVLGITRNSEDAQIKQAYRRLALKHHPLKSNEPSSAEIFRQIAEAYDVLSDPMKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGKPEKVFHEFFGGNNPFSEFFDAEGSEVDLNFGGLQGRGVKKQDPQVERDLYLSLEDLFFGCTKKIKISRRVLNEDGYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLLNIPINDIIHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT", "length": 316 }, "evidence": [ { "id": "E1C599", "url": "https://omabrowser.org/oma/group/E1C599/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80Y75-1", "protein_name": "DnaJ homolog subfamily B member 13", "gene_name": "Dnajb13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLDYYAVLQVTRNSEDAQIKKAYRKLALKNHPLKSSEPGAPEIFKQIAEAYDVLSDPVKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGNPDKVFHEFFGGDNPFSEFFDAEGNDIDLNFGGLWGRGVQKQDPPIERDLYLSLEDLFFGCTKKIKISRRVLNEDRYSSTIKDKILTIDVRPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRREHDNLFFVYPIPLGKALTCCTVEVKTLDDRLLNIPINDIVHPKYFKIVPGEGMPLPENPSKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT", "length": 316 }, "evidence": [ { "id": "E1C599", "url": "https://omabrowser.org/oma/group/E1C599/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" }, { "name": "radial spoke", "id": "GO:0001534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001534", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" }, { "name": "sperm head-tail coupling apparatus", "id": "GO:0120212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120212", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "axonemal central apparatus assembly", "id": "GO:1904158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904158", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" }, { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "E1C599", "url": "https://www.uniprot.org/uniprotkb/E1C599" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C599-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 316, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C599-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C599" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C599", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C599" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 68, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C5A6-1", "uniprot_ac": "E1C5A6", "uniprot_id": "E1C5A6_CHICK", "mass": { "chemical_mass": 27366.0, "monoisotopic_mass": 27366.0 }, "refseq": { "ac": "NP_001244256", "name": "regulator of G-protein signaling 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244256" }, "gene_names": [ { "name": "RGS18", "type": "recommended", "evidence": [ { "id": "E1C5A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5A6" } ] }, { "name": "RGS18", "type": "synonym", "evidence": [ { "id": "NP_001244256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244256" } ] } ], "protein_names": [ { "name": "Regulator of G-protein signaling 18", "type": "synonym", "evidence": [ { "id": "E1C5A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5A6/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 18", "type": "synonym", "evidence": [ { "id": "NP_001244256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244256" } ] }, { "name": "regulator of G-protein signalling 18", "type": "synonym", "evidence": [ { "id": "NP_001244256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244256" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01099125.1, HAEK01098970.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000237.1. On Mar 31, 2012 this sequence version replaced XP_422204.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001244256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244256" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5A6", "url": "https://www.uniprot.org/uniprotkb/E1C5A6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RGS18", "url": "https://www.uniprot.org/uniprotkb/E1C5A6", "locus": { "chromosome": "8", "start_pos": 3657274, "end_pos": 3666109, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012818", "url": "https://www.ensembl.org/id/ENSGALG00010012818" } ] } } ], "crossref": [ { "id": "E1C5A6", "url": "https://alphafold.ebi.ac.uk/entry/E1C5A6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021143", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021143", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08712", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08712", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424361", "url": "https://www.ncbi.nlm.nih.gov/gene/424361", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ 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"https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001244256", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244256", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C5A6", "url": "https://www.uniprot.org/uniprotkb/E1C5A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5A6-1", "url": "https://www.uniprot.org/uniprotkb/E1C5A6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENPLLLFPQLNISASKDKSYYKVMKPTVKEEPNKASKPGAKQKRNRLSLLLQKSELHEAEHLGKPTNLTKAPSVSPEEAMKWGESFDKLLSQKDGLDAFTRFLKTEFSEENIEFWIACEDYKKSKTTNELFPKAKTIYEMFIRKDAPKEVNLDFKTKEVTSQNIEQPVITTFDAAQNTVYRLMEQDSYPRFLRSDLYLNLVKGRNPGRPTLRRRSRSFTVNDFQGVRPDFTIWQ", "length": 235, "header": "tr|E1C5A6-1|E1C5A6_CHICK Isoform 1 of 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{ "uniprot_canonical_ac": "E1C5C5-1", "uniprot_ac": "E1C5C5", "uniprot_id": "E1C5C5_CHICK", "mass": { "chemical_mass": 20956.0, "monoisotopic_mass": 20956.0 }, "refseq": {}, "gene_names": [ { "name": "SELENOS", "type": "recommended", "evidence": [ { "id": "E1C5C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ] } ], "protein_names": [ { "name": "Selenoprotein S", "type": "synonym", "evidence": [ { "id": "E1C5C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5C5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5C5", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SELENOS", "url": 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"url": "https://www.ensembl.org/id/ENSGALP00010027497.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Derlin-1-VIMP complex", "id": "GO:0036502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036502", "evidence": [ { "database": "UniProtKB", "id": "E1C5C5", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ], "pmid": "" }, { "name": "Derlin-1 retrotranslocation complex", "id": "GO:0036513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036513", "evidence": [ { "database": "UniProtKB", "id": "E1C5C5", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1C5C5", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "E1C5C5", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ], "pmid": "" }, { "name": "retrograde protein transport, ER to cytosol", "id": "GO:0030970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030970", "evidence": [ { "database": "UniProtKB", "id": "E1C5C5", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ], "pmid": "" }, { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "E1C5C5", "url": "https://www.uniprot.org/uniprotkb/E1C5C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C5C5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 192, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C5C5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C5C5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C5C9-1", "uniprot_ac": "E1C5C9", "uniprot_id": "E1C5C9_CHICK", "mass": { "chemical_mass": 52360.0, "monoisotopic_mass": 52360.0 }, "refseq": { "ac": "XP_415377", "name": "zinc finger and BTB domain-containing protein 43 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415377" }, "gene_names": [ { "name": "ZBTB43", "type": "recommended", "evidence": [ { "id": "E1C5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ] }, { "name": "ZBTB43", "type": "synonym", "evidence": [ { "id": "XP_415377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415377" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 43", "type": "recommended", "evidence": [ { "id": "E1C5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5C9/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 297B", "type": "synonym", "evidence": [ { "id": "E1C5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5C9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 43 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_415377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415377" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052548.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415377" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB43", "url": "https://www.uniprot.org/uniprotkb/E1C5C9", "locus": { "chromosome": "17", "start_pos": 10863206, "end_pos": 10854644, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010028675", "url": "https://www.ensembl.org/id/ENSGALG00010028675" } ] } } ], "crossref": [ { "id": "E1C5C9", "url": "https://alphafold.ebi.ac.uk/entry/E1C5C9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000000934", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000000934", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18227", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18227", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "417091", "url": "https://www.ncbi.nlm.nih.gov/gene/417091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:417091", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IEMVAGI", "url": "https://omabrowser.org/oma/group/IEMVAGI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C5C9", "url": "https://www.orthodb.org/?gene=E1C5C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415377", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5C9-1", "url": "https://www.uniprot.org/uniprotkb/E1C5C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGSSSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHLFRAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLSTYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKMNHGSDHQSPSSSSYNGLAETFELGSGGQTEFHKVQELRDGENEEESSKDELSCQLTEHEYLPSNSSTEHDRLSTGMTSQDGEEGTSDSAEYQYTRPIYSKPSIMSHKRWIHVKPERFEQDCEGVDNPYDEHQVSESMNAIQADHSIQSSGVEDFHIADKKMEAEFDEQADESNYDEQVDFYGSSMEEFSGERADGNLSAHRQDLMIATGYGEGIEMAAGIKEETSLTGFSHADKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICGKRFMWRDSFHRHVTSCTKSYQASKAEQSTTEMN", "length": 464, "header": "tr|E1C5C9-1|E1C5C9_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 43 OS=Gallus gallus OX=9031 GN=ZBTB43 PE=3 SV=1 CANONICAL=E1C5C9-1" }, "isoforms": [ { "isoform_ac": "E1C5C9-1", "url": "https://www.uniprot.org/uniprotkb/E1C5C9/entry#E1C5C9-1", "sequence": { "sequence": "MESGSSSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHLFRAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLSTYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKMNHGSDHQSPSSSSYNGLAETFELGSGGQTEFHKVQELRDGENEEESSKDELSCQLTEHEYLPSNSSTEHDRLSTGMTSQDGEEGTSDSAEYQYTRPIYSKPSIMSHKRWIHVKPERFEQDCEGVDNPYDEHQVSESMNAIQADHSIQSSGVEDFHIADKKMEAEFDEQADESNYDEQVDFYGSSMEEFSGERADGNLSAHRQDLMIATGYGEGIEMAAGIKEETSLTGFSHADKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICGKRFMWRDSFHRHVTSCTKSYQASKAEQSTTEMN", "length": 464, "header": "tr|E1C5C9-1|E1C5C9_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 43 OS=Gallus gallus OX=9031 GN=ZBTB43 PE=3 SV=1 CANONICAL=E1C5C9-1" }, "locus": { "chromosome": "17", "start_pos": 10857453, "end_pos": 10856062, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010069418.1", "url": "https://www.ensembl.org/id/ENSGALT00010069418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010042769.1", "url": "https://www.ensembl.org/id/ENSGALP00010042769.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:417091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:417091", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A6M7-1", "protein_name": "Zinc finger and BTB domain-containing protein 43", "gene_name": "ZBTB43", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKPERFEQACEGMDVHAPYDEHQVTESINTMQTEHSVQPSGVEEDFHIGEKKVEAEFDEQADESNYDEQVDFYGSSMEEFSGERSDGNLIGHRQEAALASGYTENIEMVTGIKEEASHLGFSASDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQNTTEAN", "length": 467 }, "evidence": [ { "id": "E1C5C9", "url": "https://omabrowser.org/oma/group/E1C5C9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AFN4-1", "protein_name": "Zinc finger and BTB domain containing 43", "gene_name": "Zbtb43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPGTNSFQVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFQAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLFSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKLNHGSDHQSPSSSNYNGLAESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQVTEHEYLPSNSSTEHDRLSTEMASQDGEEGTNDSTEFHYTRPLYSKPSIMPHRRWIHVKPERLEQPWDGMDVHAAYDEHQVSESVNTMQTDHSAQPSGAEEEFQIVEKKVEVEFDEHAEGSNYDEQVDFYGSSMEEFSGEKLGGGLIGHKQETALAAGYSENIEMVMGIKEEASHLGFSATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCSVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAGQNTTEAN", "length": 467 }, "evidence": [ { "id": "E1C5C9", "url": "https://omabrowser.org/oma/group/E1C5C9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43298-1", "protein_name": "Zinc finger and BTB domain-containing protein 43", "gene_name": "ZBTB43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKPERLEQACEGMDVHATYDEHQVTESINTVQTEHTVQPSGVEEDFHIGEKKVEAEFDEQADESNYDEQVDFYGSSMEEFSGERSDGNLIGHRQEAALAAGYSENIEMVTGIKEEASHLGFSATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQNTTEAN", "length": 467 }, "evidence": [ { "id": "E1C5C9", "url": "https://omabrowser.org/oma/group/E1C5C9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAI4-1", "protein_name": "Zinc finger and BTB domain-containing protein 43", "gene_name": "Zbtb43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGTNSFQVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFQAHKAVLAASSPYFCDQVLLKNSRRIVLPDVMNPRVFENILLFSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEGNPTVLCQKLNHGSDHQSPSSSNYNGLVESFELGSGGHTDFPKAQELRDGENEEESTKDELSSQVTEHEYLPSNSSTEHDRLSTEMASQDGEEGTNDSTEFHYTRPLYSKPSIMAHRRWIHVKPERLEQAWDGMDVHAAYDEHQVTESVNTMQTDHSAQPSGAEEEFQIVEKKVEVEFDEQAEGSSYDEQVDFYGSSMEEFSGEKLGGNLIGHKQEAALAAGYSENIEMAMGIKEEASHLGFSATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCSVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQNTTEAN", "length": 467 }, "evidence": [ { "id": "E1C5C9", "url": "https://omabrowser.org/oma/group/E1C5C9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor binding", "id": "GO:0001025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001025", "evidence": [ { "database": "UniProtKB", "id": "E1C5C9", "url": "https://www.uniprot.org/uniprotkb/E1C5C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C5C9-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 464, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C5C9-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C5C9" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 }, { "start_pos": 330, "end_pos": 332 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C5D4-1", "uniprot_ac": "E1C5D4", "uniprot_id": "E1C5D4_CHICK", "mass": { "chemical_mass": 76970.0, "monoisotopic_mass": 76970.0 }, "refseq": { "ac": "NP_001186358", "name": "nephrocystin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186358" }, "gene_names": [ { "name": "NPHP1", "type": "recommended", "evidence": [ { "id": "E1C5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ] }, { "name": "NPHP1", "type": "synonym", "evidence": [ { "id": "NP_001186358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186358" } ] }, { "name": "nephrocystin-1", "type": "synonym", "evidence": [ { "id": "NP_001186358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186358" } ] } ], "protein_names": [ { "name": "Nephrocystin 1", "type": "synonym", "evidence": [ { "id": "E1C5D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5D4/entry#names_and_taxonomy" } ] }, { "name": "nephrocystin-1", "type": "synonym", "evidence": [ { "id": "NP_001186358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186358" } ] }, { "name": "nephronophthisis 1 (juvenile)", "type": "synonym", "evidence": [ { "id": "NP_001186358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186358" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.170505.1, SRR13267649.268829.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000060.1. On Dec 9, 2010 this sequence version replaced XP_419298.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001186358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186358" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPHP1", "url": "https://www.uniprot.org/uniprotkb/E1C5D4", "locus": { "chromosome": "3", "start_pos": 3250229, "end_pos": 3269465, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016980", "url": "https://www.ensembl.org/id/ENSGALG00010016980" } ] } } ], "crossref": [ { "id": "E1C5D4", "url": "https://alphafold.ebi.ac.uk/entry/E1C5D4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008195", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008195", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11770", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11770", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421223", "url": "https://www.ncbi.nlm.nih.gov/gene/421223", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421223", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421223", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYLIALM", "url": "https://omabrowser.org/oma/group/CYLIALM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C5D4", "url": "https://www.orthodb.org/?gene=E1C5D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15176:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15176:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5D4-1", "url": "https://www.uniprot.org/uniprotkb/E1C5D4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGRRARSPLQRVQRQSRELRAQVEALRGEGADAAVGRRAALRQRCFQLQKLVDENINTLHSLKKADEPAPVGNYNQRKEEEEKLLLKLSQQLQKFCHILDQDNVATNDTVSEGRQKDPQREDKVKEEAESADDNGESSEEGESEETDEEDEDKLLDDPDVKECIAVGNFNAQQDGDLTFTKGEVLLIHDKKADGWWVAENSKGERGLVPRTYLAVHNEDEENQEESDEHIEVVDETADGTEIRKRTDSHWSAVRKAITESDTVEILATMGAVPTGFRLSTLSQLLEEGNQFRASYFLQPKLTPSQLAFKDLVWDSEKNTICPIPTRVSLIVTLCSCKTIPLPAASIQVLSRHVRLCLFDGNRVLSNIHTVRATWQPKNPQMWTFSPRVTGILPSLLDGDCFVRSNSLSSDIGLLLELGITYIRNSTGERRELSCGWAFQKLFTSDGMPVPSKMYELLLNGGTPYERGVEVDPSLSRRAGSGVFHQLISLKKQPVLVVKLRSLSTQSKDILNLLPETLIGSMCYIHLLIFYRQILGDALLRDRINMQSAELICNPILATFPQLVDQPDLMDALRSAWADRERTLKRSEKRDREFLKSVFILVYHDSAFPLLRSTLLPSYKWAEEESEASRWRVIADFLRKSQEKDGALQSLLSAENTHTAFDISELAYDFLGETRKNNPTV", "length": 681, "header": "tr|E1C5D4-1|E1C5D4_CHICK Isoform 1 of Nephrocystin 1 OS=Gallus gallus OX=9031 GN=NPHP1 PE=1 SV=2 CANONICAL=E1C5D4-1" }, "isoforms": [ { "isoform_ac": "E1C5D4-1", "url": "https://www.uniprot.org/uniprotkb/E1C5D4/entry#E1C5D4-1", "sequence": { "sequence": "MTGRRARSPLQRVQRQSRELRAQVEALRGEGADAAVGRRAALRQRCFQLQKLVDENINTLHSLKKADEPAPVGNYNQRKEEEEKLLLKLSQQLQKFCHILDQDNVATNDTVSEGRQKDPQREDKVKEEAESADDNGESSEEGESEETDEEDEDKLLDDPDVKECIAVGNFNAQQDGDLTFTKGEVLLIHDKKADGWWVAENSKGERGLVPRTYLAVHNEDEENQEESDEHIEVVDETADGTEIRKRTDSHWSAVRKAITESDTVEILATMGAVPTGFRLSTLSQLLEEGNQFRASYFLQPKLTPSQLAFKDLVWDSEKNTICPIPTRVSLIVTLCSCKTIPLPAASIQVLSRHVRLCLFDGNRVLSNIHTVRATWQPKNPQMWTFSPRVTGILPSLLDGDCFVRSNSLSSDIGLLLELGITYIRNSTGERRELSCGWAFQKLFTSDGMPVPSKMYELLLNGGTPYERGVEVDPSLSRRAGSGVFHQLISLKKQPVLVVKLRSLSTQSKDILNLLPETLIGSMCYIHLLIFYRQILGDALLRDRINMQSAELICNPILATFPQLVDQPDLMDALRSAWADRERTLKRSEKRDREFLKSVFILVYHDSAFPLLRSTLLPSYKWAEEESEASRWRVIADFLRKSQEKDGALQSLLSAENTHTAFDISELAYDFLGETRKNNPTV", "length": 681, "header": "tr|E1C5D4-1|E1C5D4_CHICK Isoform 1 of Nephrocystin 1 OS=Gallus gallus OX=9031 GN=NPHP1 PE=1 SV=2 CANONICAL=E1C5D4-1" }, "locus": { "chromosome": "3", "start_pos": 3269461, "end_pos": 3250342, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010041000.1", "url": "https://www.ensembl.org/id/ENSGALT00010041000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023964.1", "url": "https://www.ensembl.org/id/ENSGALP00010023964.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421223", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LIM9-1", "protein_name": "Nephrocystin-1", "gene_name": "Nphp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLARRPRDPLQALRRRGQELKLQVDSLVTESQLTGALEPSKRRDIYQRCIQLKQAVDENKNALQKLNKADEAAPVGNYEQRKEEEHTLLEKLACQLQELAVGISRKDTLKVEAHSDKEEDDTTEDDEEETEETGGEEEESEGDEEGKQEQASPEHAETVTYIALGDFAAQQAGDLTFKKGDILHIIEKRPDGWWLAKDAEGGEGLIPRTYLEPYNKEDKLESSEGSEEGDEEGVGEDGEDGEDGEDGEEDVEVVDETADGAQVKQRTDSHWSAVRKAISEINTVDVLATMGAIPAGFRPSTLSQLLDEGKAPYSIWLDLLARKPQGSPASVPQHWDTGGRFRASYFLQPELTTSQLAFRDLTWDAKTGTIMSRPSRVSLILTLWSCKMIPLPGTSIQVLSRHIRLCLFDGSKVLSNIHTVRAVWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSTPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGVEVDPSVSRRAQGSVFRQMISVRRQPQLLVKLRSLNRRSRAMLSLLPETLVGSMCSAHLLIFYRQILGDVLLRDRTSLQSADLISHPVLATFPLLLEQPDVMDALRSSWAEKESTLKRSEKRDKELLKAEFLLVYHDCVLPLLHSTLLPPFRWAEEETEAARWKAIADFLKQSRENEGSLKALLSPDGVHKPFDLSEQTYDFLGEIRKNSG", "length": 728 }, "evidence": [ { "id": "E1C5D4", "url": "https://omabrowser.org/oma/group/E1C5D4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K7GQD8-1", "protein_name": "Nephrocystin-1", "gene_name": "NPHP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLARRQRDPLQSLQRRSQELKKQVEGLLSESRLKGALEASKRQDIYQRCIQLKQAIDENKNALQKLNKADEPAPVGNYNQKKEDEHNLLDKLTHQLQELSVSISKENITETQALTEREEDDSSAEEDEEEEDEDKEESEESGGEEEETEEEEEKKQENEPHQEAPSGRYIAVGDFTAQQVGDLTFKKGEILLIIEKNPDGWWLAKNAQGNKGLTPRTYLEPYNEEGEESSEEGSDEDTEVGNETAEGAEVKQRADSHWSAVRKAISEQINTVDVLTTMGAIPAGFRPSTLFQLLEEGNQFRASYFLQPELSPSQLAFKDLLWDAKTGAIRSRPSRVSLILTLWSCKMIPLPGASIQVLSRHVRLCVFDGSKVLSNIHTVRATWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSSPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGIPVPAKTYELFLNGGTPYEKGVEVDPSVSRRAHGSVFHQMMTMRRQPQLLVKLRSLNRRSRNMLSLLPETLIGSMCSTHLLIFYRQILGDVLLKDRMSMDSADLISNPVLATFPKLLEQPDIMDALRSSWAEKESSLKRSEKSDKELLKAAFLLVYHDCALPLLHSTLLPQLRWAEEESEAARWKVITDFLKQNQENDGALQALLSPEGVHEPFDISEQTYDFLGEIRKNTA", "length": 687 }, "evidence": [ { "id": "E1C5D4", "url": "https://omabrowser.org/oma/group/E1C5D4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O15259-1", "protein_name": "Nephrocystin-1", "gene_name": "NPHP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLARRQRDPLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLEPYSEEEEGQESSEEGSEEDVEAVDETADGAEVKQRTDPHWSAVQKAISEAGIFCLVNHVSFCYLIVLMRNRMETVEDTNGSETGFRAWNVQSRGRIFLVSKPVLQINTVDVLTTMGAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDGNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFYRQILGDVLLKDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARWKVITDFLKQNQENQGALQALLSPDGVHEPFDLSEQTYDFLGEMRKNAV", "length": 732 }, "evidence": [ { "id": "E1C5D4", "url": "https://omabrowser.org/oma/group/E1C5D4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QY53-1", "protein_name": "Nephrocystin-1", "gene_name": "Nphp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLARRPRDPLQALRRRGQELKLQVDSLVTESQLTGALEPSKRREIYQRCIQLKQAVDENKNTLQKLNKADEAAPVGNYEQRKEEEHSLLEKLACQLQELAVSISRKDALKVEAHSDKEEDDTTEDDEEETGGEEEESEGDGEGKQEQASPKQAETETVTYIALGDFAAQQTGDLTFKKGDVLHIIEKKPDGWWLAKDAEGVEGLIPRTYLEPYNKEDKLESSEGSEEGGEEDGEEDVEVVDETADGAQVKQRTDSHWSAVRKAISEQINTVDVLATMGAIPAGFRPSTLSQLLDEAGNQFRASYFLQPELTTSQLAFRDLTWDAKAGTIMSRPSRVSLILTLWSCKMIPLPGTSIQVLSRHIRLCLFDGSKVLSNIHTVRAVWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSTPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGVEVDPSVSRRAQGSVFRQMISVRRQPQLLVKLRSLNRRSRAMLSLLPETLVGSMCSAHLLIFYRQILGDVLLRDRTNLQSADLISHPVLATFPLLLEQPDVMDALRSSWSEKESTLKRAEKRDKELLKAEFLLVYHDCVLPLLHSTLLPPFRWAEEETEAARWKAIADFLKQSRENEGSLKALLSPDGVHKPFDLSEQTFDFLGEIRKNSG", "length": 687 }, "evidence": [ { "id": "E1C5D4", "url": "https://omabrowser.org/oma/group/E1C5D4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of bicellular tight junction assembly", "id": "GO:1903348", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903348", "evidence": [ { "database": "UniProtKB", "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ], "pmid": "" }, { "name": "protein localization involved in establishment of planar polarity", "id": "GO:0090251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090251", "evidence": [ { "database": "UniProtKB", "id": "E1C5D4", "url": "https://www.uniprot.org/uniprotkb/E1C5D4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C5D4-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 681, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C5D4-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C5D4" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C5N7-1", "uniprot_ac": "E1C5N7", "uniprot_id": "E1C5N7_CHICK", "mass": { "chemical_mass": 24044.0, "monoisotopic_mass": 24044.0 }, "refseq": { "ac": "XP_417337", "name": "peroxisomal membrane protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417337" }, "gene_names": [ { "name": "PXMP4", "type": "recommended", "evidence": [ { "id": "E1C5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5N7" } ] }, { "name": "PXMP4", "type": "synonym", "evidence": [ { "id": "XP_417337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417337" } ] } ], "protein_names": [ { "name": "Peroxisomal membrane protein 4", "type": "recommended", "evidence": [ { "id": "E1C5N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5N7/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal membrane protein 4", "type": "synonym", "evidence": [ { "id": "XP_417337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417337" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417337" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5N7", "url": "https://www.uniprot.org/uniprotkb/E1C5N7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PXMP4", "url": "https://www.uniprot.org/uniprotkb/E1C5N7", "locus": { "chromosome": "20", "start_pos": 2509574, "end_pos": 2505624, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022044", "url": "https://www.ensembl.org/id/ENSGALG00010022044" } ] } } ], "crossref": [ { "id": "E1C5N7", "url": "https://alphafold.ebi.ac.uk/entry/E1C5N7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003042", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003042", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419153", "url": "https://www.ncbi.nlm.nih.gov/gene/419153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419153", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419153", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMVFLFR", "url": "https://omabrowser.org/oma/group/VMVFLFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C5N7", "url": "https://www.orthodb.org/?gene=E1C5N7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15460", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15460", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15460:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15460:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02466", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02466", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9603798", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_417337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C5N7", "url": "https://www.uniprot.org/uniprotkb/E1C5N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5N7-1", "url": "https://www.uniprot.org/uniprotkb/E1C5N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGAAPPAALLRAINALLLQRRYRAALAVLKGFRNGAVYGAKIRAPHALVMTFLFRSGSLREKLKSIAQATYTHSRNLAYFVFTYKGLMALQSRLQGKKIPFHSFFAACIGGWLVFGENNPINSQIVMYLLSRILFGLSRLAVEKGYIPQPRQDPFPLVAALVWGTVLWLFEYHRQTLQPSLQASMTYLYDDSNVWHDISDFLIYNKKPESK", "length": 213, "header": "tr|E1C5N7-1|E1C5N7_CHICK Isoform 1 of Peroxisomal membrane protein 4 OS=Gallus gallus OX=9031 GN=PXMP4 PE=1 SV=1 CANONICAL=E1C5N7-1" }, "isoforms": [ { "isoform_ac": "E1C5N7-1", "url": "https://www.uniprot.org/uniprotkb/E1C5N7/entry#E1C5N7-1", "sequence": { "sequence": "MAGGAAPPAALLRAINALLLQRRYRAALAVLKGFRNGAVYGAKIRAPHALVMTFLFRSGSLREKLKSIAQATYTHSRNLAYFVFTYKGLMALQSRLQGKKIPFHSFFAACIGGWLVFGENNPINSQIVMYLLSRILFGLSRLAVEKGYIPQPRQDPFPLVAALVWGTVLWLFEYHRQTLQPSLQASMTYLYDDSNVWHDISDFLIYNKKPESK", "length": 213, "header": "tr|E1C5N7-1|E1C5N7_CHICK Isoform 1 of Peroxisomal membrane protein 4 OS=Gallus gallus OX=9031 GN=PXMP4 PE=1 SV=1 CANONICAL=E1C5N7-1" }, "locus": { "chromosome": "20", "start_pos": 2508303, "end_pos": 2505690, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053596.1", "url": "https://www.ensembl.org/id/ENSGALT00010053596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032292.1", "url": "https://www.ensembl.org/id/ENSGALP00010032292.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419153", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419153", "resource": "KEGG Pathway" }, { "id": "R-GGA-9603798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603798", "resource": "Reactome", "description": "Class I peroxisomal membrane protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QFW3-1", "protein_name": "Peroxisomal membrane protein 4", "gene_name": "pxmp4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAASDLFKTLLYTVNNLLQQHKYKTALAVLKGFRNGAVYGAKIRAPHALVMTFLFRSGSLREKFRAIAQATYTHSRNLACFVFTYKGLQALQQQLQGKQMQSHSFLAACVGGWLVFGENNNINSQINMYLLSRILFALSRLAVEKGLIPQPKKDPFPLFATLVWGIVLWLFEYYPHTLQPSLQSSMNYLYHDSNTWHDITDSLIYNKPKAN", "length": 211 }, "evidence": [ { "id": "E1C5N7", "url": "https://omabrowser.org/oma/group/E1C5N7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HAM9-1", "protein_name": "Peroxisomal membrane protein 4", "gene_name": "Pxmp4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASPPQLQALLQAVNTLLRKRRYHAVLALLKGFRNGAVYGVKIRAPHALVMTFLFRSGSLQEKLQAILKATYTHSRNLACFVFIYKSLCALQSHVQGETHQMHSFLAAFIGGLLVFRKNNNINSQINMYLTSRVLFALCRLGVEKGYIPKLSWDPFPLHTAVIWGLVLWLFEYHRPTLQPSLQSSMTYLYEDSNVWHDISDFLIFNKSRPSK", "length": 212 }, "evidence": [ { "id": "E1C5N7", "url": "https://omabrowser.org/oma/group/E1C5N7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P59382-1", "protein_name": "Peroxisomal membrane protein 4", "gene_name": "Pxmp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPPQLRALLQAVNKLLRQRRYHAALAVIKGFRNGAVYGVKIRAPHALVMTFLFRSGSLQEKLQAILKATYTHSRNLACFVFTYKSLQALQSHVQGGTHQMHSFLAAFIGGLLLFGENNNINSQINMYLTSRVLFALCRLGVEKGYIPALKWDPFPLHTAVIWGLVLWLFEYHRPTLQPSLQSSMTYLYEDSNVWHDLSDFLIFNKSRPSK", "length": 212 }, "evidence": [ { "id": "E1C5N7", "url": "https://omabrowser.org/oma/group/E1C5N7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JJW0-1", "protein_name": "Peroxisomal membrane protein 4", "gene_name": "Pxmp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPPQLQALLQAVNKLLRQRRYHAALAVIKGFRNGAVYGVKIRAPHALVMTFLFRSGSLREKLQAILKATYIHSRNLACFVFAYKSLHALQSHVQGETHQMHSFLAAFIGGLLLFGENNNINSQINMYLTSRVLYALCRLGVEKGYIPALKWDPFPLHTAVIWGLVLWLFEYHRPTLQPSLQSSMTYLYEDSNVWHDLSDFLIFNKSHPSK", "length": 212 }, "evidence": [ { "id": "E1C5N7", "url": "https://omabrowser.org/oma/group/E1C5N7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6I8-1", "protein_name": "Peroxisomal membrane protein 4", "gene_name": "PXMP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPPQLRALLVVVNALLRKRRYHAALAVLKGFRNGAVYGAKIRAPHALVMTFLFRNGSLQEKLWAILQATYIHSWNLARFVFTYKGLRALQSYIQGKTYPAHAFLAAFLGGILVFGENNNINSQINMYLLSRVLFALSRLAVEKGYIPEPRWDPFPLLTAVVWGLVLWLFEYHRSTLQPSLQSSMTYLYEDSNVWHDISDFLVYNKSRPSN", "length": 212 }, "evidence": [ { "id": "E1C5N7", "url": "https://omabrowser.org/oma/group/E1C5N7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisomal membrane", "id": "GO:0005778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005778", "evidence": [ { "database": "UniProtKB", "id": "E1C5N7", "url": "https://www.uniprot.org/uniprotkb/E1C5N7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C5N7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 213, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C5N7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C5N7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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{ "uniprot_canonical_ac": "E1C5Q2-1", "uniprot_ac": "E1C5Q2", "uniprot_id": "E1C5Q2_CHICK", "mass": { "chemical_mass": 21434.0, "monoisotopic_mass": 21434.0 }, "refseq": { "ac": "NP_001280172", "name": "lysM and putative peptidoglycan-binding domain-containing protein 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280172" }, "gene_names": [ { "name": "LYSMD2", "type": "recommended", "evidence": [ { "id": "E1C5Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2" } ] }, { "name": "LYSMD2", "type": "synonym", "evidence": [ { "id": "NP_001280172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280172" } ] } ], "protein_names": [ { "name": "LysM and putative peptidoglycan-binding domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "E1C5Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2/entry#names_and_taxonomy" } ] }, { "name": "LysM, putative peptidoglycan-binding, domain containing 2", "type": "synonym", "evidence": [ { "id": "NP_001280172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280172" } ] }, { "name": "lysM and putative peptidoglycan-binding domain-containing protein 2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001280172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280172" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR386172.1, HAEK01027479.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Jun 7, 2014 this sequence version replaced XP_413806.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).", "evidence": [ { "database": "RefSeq", "id": "NP_001280172", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280172" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5Q2", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LYSMD2", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2", "locus": { "chromosome": "10", "start_pos": 9116986, "end_pos": 9106497, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022539", "url": "https://www.ensembl.org/id/ENSGALG00010022539" } ] } } ], "crossref": [ { "id": "E1C5Q2", "url": "https://alphafold.ebi.ac.uk/entry/E1C5Q2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000018976", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000018976", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415423", "url": "https://www.ncbi.nlm.nih.gov/gene/415423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415423", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRMDVQI", "url": "https://omabrowser.org/oma/group/HRMDVQI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RZQ5", "url": "https://www.orthodb.org/?gene=A0A1L1RZQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQP3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C5Q2", "url": "https://www.orthodb.org/?gene=E1C5Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20932:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20932:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001280172", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RZQ5", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RZQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RZQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5Q2", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5Q2-1", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAESPREEPPGGPESEAELSQRLALIKARSYGSTASVAAPLAERYVEHRLSAGDTLQGIALKYGVTMEQIKRANKLFTNDCIFLRKTLNIPVISEKPLLFNGLNSLESPENETVDSSPSCEEGLVTAQEESSSSPSPQEPDNQPTAPEELSAKDFLQRLDLQIKLSKQAARKLKDDSVREEENEEGPYATSSYHQ", "length": 195, "header": "tr|E1C5Q2-1|E1C5Q2_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 2 OS=Gallus gallus OX=9031 GN=LYSMD2 PE=4 SV=2 CANONICAL=E1C5Q2-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RZQ5-1", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2/entry#A0A1L1RZQ5-1", "sequence": { "sequence": "MAESPREEPPGGPESEAELSQRLALIKARSYGSTASVAAPLAERYVEHRLSAGDTLQGIALKYGVTRGGE", "length": 70, "header": "tr|A0A1L1RZQ5-1|A0A1L1RZQ5_CHICK Computationally mapped isoform of LysM and putative peptidoglycan-binding domain-containing protein 2 OS=Gallus gallus OX=9031 GN=LYSMD2 PE=4 SV=1 CANONICAL=E1C5Q2-1" }, "locus": { "chromosome": "10", "start_pos": 9116209, "end_pos": 9106668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054859.1", "url": "https://www.ensembl.org/id/ENSGALT00010054859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033159.1", "url": "https://www.ensembl.org/id/ENSGALP00010033159.1" } ] } }, { "isoform_ac": "A0A8V0ZQP3-1", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2/entry#A0A8V0ZQP3-1", "sequence": { "sequence": "MEQIKRANKLFTNDCIFLRKTLNIPVISEKPLLFNGLNSLESPENETVDSSPSCEEGLVTAQEESSSSPSPQEPDNQPTAPEELSAKDFLQRLDLQIKLSKQAARKLKDDSVRIAVLLYKSYNASILQDVLL", "length": 132, "header": "tr|A0A8V0ZQP3-1|A0A8V0ZQP3_CHICK Computationally mapped isoform of LysM domain containing 2 OS=Gallus gallus OX=9031 GN=LYSMD2 PE=4 SV=1 CANONICAL=E1C5Q2-1" }, "locus": { "chromosome": "10", "start_pos": 9112008, "end_pos": 9111404, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054848.1", "url": "https://www.ensembl.org/id/ENSGALT00010054848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033152.1", "url": "https://www.ensembl.org/id/ENSGALP00010033152.1" } ] } }, { "isoform_ac": "E1C5Q2-1", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2/entry#E1C5Q2-1", "sequence": { "sequence": "MAESPREEPPGGPESEAELSQRLALIKARSYGSTASVAAPLAERYVEHRLSAGDTLQGIALKYGVTMEQIKRANKLFTNDCIFLRKTLNIPVISEKPLLFNGLNSLESPENETVDSSPSCEEGLVTAQEESSSSPSPQEPDNQPTAPEELSAKDFLQRLDLQIKLSKQAARKLKDDSVREEENEEGPYATSSYHQ", "length": 195, "header": "tr|E1C5Q2-1|E1C5Q2_CHICK Isoform 1 of LysM and putative peptidoglycan-binding domain-containing protein 2 OS=Gallus gallus OX=9031 GN=LYSMD2 PE=4 SV=2 CANONICAL=E1C5Q2-1" }, "locus": { "chromosome": "10", "start_pos": 9116246, "end_pos": 9106668, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054855.1", "url": "https://www.ensembl.org/id/ENSGALT00010054855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033157.1", "url": "https://www.ensembl.org/id/ENSGALP00010033157.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415423", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8J8XSR6-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 2", "gene_name": "Lysmd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGRGGCTVARSGFSRTLSRLHGSEVHMGSRTPPWASVGPQASARSRRAFSGRTRTLQPRLSSLIAISTGTSGAWEKLAQSGARHAGPAAPRLGLAPAAPAARPAAALVRRKRRRRRRRPLGELGAPAALAGPMADLSPAPALREGGPRAHRPSAPSPPLRSRSTSEPEEAELSLSLARTKTRSYGSTASVRAPLGAGVIERHVEHRVRAGDTLQGIALKYGVTMEQIKRANKLFTNDCIFLKKTLSIPILSEKPLVFNGLNSIDSPESETVDSSFCHEEEPVVSEEELPPPSPQDTDPKPAQPEEVSARDFLQRLDLQIKLSTQAARKLKEENRDEESPYAASLYHS", "length": 348 }, "evidence": [ { "id": "E1C5Q2", "url": "https://omabrowser.org/oma/group/E1C5Q2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1JQA8-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 2", "gene_name": "LYSMD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADSSPAPSLRAGGPREPRPSAPSPPPPHSRLGSEAEEAELSLSLARTKTRSYGSTASVRAPLGAGVIERHVEHRVRAGDTLQGIALKYGVSMEQIKRANKLFTNDCIFLKKTLNIPVISEKPLLFNGLNSVDSPENETVDSFSHEEELVAAGEDVSPLSPQELDVQPMQPEEVSARDFLQRLDLQIKLSTQAAKKLKGESRDEEGLYTASLYHS", "length": 215 }, "evidence": [ { "id": "E1C5Q2", "url": "https://omabrowser.org/oma/group/E1C5Q2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IV50-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 2", "gene_name": "LYSMD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSPALSLREGGPRAPRPSAPSPPPRSRSGSESEEAELSLSLARTKTRSYGSTASVRAPLGAGVIERHVEHRVRAGDTLQGIALKYGVTMEQIKRANKLFTNDCIFLKKTLNIPVISEKPLLFNGLNSIDSPENETADNSFSQEEEPVVAGEDLPPPSPQESDVQPVQPEEVSARDFLQRLDLQIKLSTQAAKKLKEESRDEESPYATSLYHS", "length": 215 }, "evidence": [ { "id": "E1C5Q2", "url": "https://omabrowser.org/oma/group/E1C5Q2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7V2-1", "protein_name": "LysM and putative peptidoglycan-binding domain-containing protein 2", "gene_name": "Lysmd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADLSPAPALREGGPRAHRPSAPSPPPRSRSTSEPEEAELSLSLARTKTRSYGSTASVRAPLGARVIERHVEHRVRAGDTLQGIALKYGVTMEQIKRANKLFTNDCIFLKKTLSIPILSEKPLLFNGLNSIDSPESETVDSSFCQEEEPVVSEEELPPPSPQDPDPKPAQPEEVSARDFLQRLDLQIKLSTQAARKLKEESRDEESPYAASLYHS", "length": 215 }, "evidence": [ { "id": "E1C5Q2", "url": "https://omabrowser.org/oma/group/E1C5Q2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C5Q2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 195, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C5Q2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C5Q2" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E1C5Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5Q2" }, { "id": "PS51782", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 90, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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{ "name": "SDR16C6", "type": "synonym", "evidence": [ { "id": "XP_015138173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138173" } ] } ], "protein_names": [ { "name": "Epidermal retinol dehydrogenase 2", "type": "recommended", "evidence": [ { "id": "E1C5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5Q4/entry#names_and_taxonomy" } ] }, { "name": "epidermal retinol dehydrogenase 2", "type": "synonym", "evidence": [ { "id": "XP_015138173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138173" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015138173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015138173" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5Q4", "url": "https://www.uniprot.org/uniprotkb/E1C5Q4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SDR16C6", "url": "https://www.uniprot.org/uniprotkb/E1C5Q4", "locus": {} } ], "crossref": [ { "id": "E1C5Q4", "url": "https://alphafold.ebi.ac.uk/entry/E1C5Q4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000022827", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000022827", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05339", "url": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C5R1-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 512, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C5R1-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C5R1" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C5R7-1", "uniprot_ac": "E1C5R7", "uniprot_id": "E1C5R7_CHICK", "mass": { "chemical_mass": 34721.0, "monoisotopic_mass": 34721.0 }, "refseq": { "ac": "NP_001020780", "name": "dnaJ homolog subfamily C member 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020780" }, "gene_names": [ { "name": "DNAJC18", "type": "recommended", "evidence": [ { "id": "E1C5R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5R7" } ] }, { "name": "DNAJC18", "type": "synonym", "evidence": [ { "id": "NP_001020780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020780" } ] } ], "protein_names": [ { "name": "DnaJ (Hsp40) homolog, subfamily C, member 18", "type": "synonym", "evidence": [ { "id": "NP_001020780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020780" } ] }, { "name": "DnaJ heat shock protein family (Hsp40) member C18", "type": "synonym", "evidence": [ { "id": "E1C5R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C5R7/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily C member 18", "type": "synonym", "evidence": [ { "id": "NP_001020780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020780" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01023711.1, HAEK01013298.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000256.1. On Jul 22, 2005 this sequence version replaced XP_414517.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001020780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020780" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C5R7", "url": "https://www.uniprot.org/uniprotkb/E1C5R7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC18", "url": "https://www.uniprot.org/uniprotkb/E1C5R7", "locus": { "chromosome": "13", "start_pos": 2070651, "end_pos": 2058284, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010008276", "url": "https://www.ensembl.org/id/ENSGALG00010008276" } ] } } ], "crossref": [ { "id": "E1C5R7", "url": "https://alphafold.ebi.ac.uk/entry/E1C5R7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002528", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002528", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416189", "url": "https://www.ncbi.nlm.nih.gov/gene/416189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416189", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TGQARHY", "url": "https://omabrowser.org/oma/group/TGQARHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C5R7", "url": "https://www.orthodb.org/?gene=E1C5R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43908", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43908", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43908:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43908:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001020780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020780", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C5R7", "url": "https://www.uniprot.org/uniprotkb/E1C5R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5R7-1", "url": "https://www.uniprot.org/uniprotkb/E1C5R7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTYTAEQLDGVRRIKSCRNYYEILGVERDATEEDLKKAYRRLALKFHPDKNRAPGATEAFKAIGNAFAVLSNPEKRLRYDEYGSDHEHVSTGQARHYNYYTEFEADITPEEIFNVFFGGHFPTGNIHMFSNVARDAHYYPRRHRNERAWTQEQEEEENRPQNSYSAFIQLMPIFIIIIVSVITQLMATNPPYSLFYKSSIGHVISRETENLQVPYYVDKNFEKNYQGAELQELERTVEKDYIDYIQTSCWKEKQQKSDLSNLAKLYRDERLKQKAESLKLEHCEKLSSLIGMHKGG", "length": 296, "header": "tr|E1C5R7-1|E1C5R7_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C18 OS=Gallus gallus OX=9031 GN=DNAJC18 PE=4 SV=1 CANONICAL=E1C5R7-1" }, "isoforms": [ { "isoform_ac": "E1C5R7-1", "url": "https://www.uniprot.org/uniprotkb/E1C5R7/entry#E1C5R7-1", "sequence": { "sequence": "MTYTAEQLDGVRRIKSCRNYYEILGVERDATEEDLKKAYRRLALKFHPDKNRAPGATEAFKAIGNAFAVLSNPEKRLRYDEYGSDHEHVSTGQARHYNYYTEFEADITPEEIFNVFFGGHFPTGNIHMFSNVARDAHYYPRRHRNERAWTQEQEEEENRPQNSYSAFIQLMPIFIIIIVSVITQLMATNPPYSLFYKSSIGHVISRETENLQVPYYVDKNFEKNYQGAELQELERTVEKDYIDYIQTSCWKEKQQKSDLSNLAKLYRDERLKQKAESLKLEHCEKLSSLIGMHKGG", "length": 296, "header": "tr|E1C5R7-1|E1C5R7_CHICK Isoform 1 of DnaJ heat shock protein family (Hsp40) member C18 OS=Gallus gallus OX=9031 GN=DNAJC18 PE=4 SV=1 CANONICAL=E1C5R7-1" }, "locus": { "chromosome": "13", "start_pos": 2069865, "end_pos": 2058358, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010019787.1", "url": "https://www.ensembl.org/id/ENSGALT00010019787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010011335.1", "url": "https://www.ensembl.org/id/ENSGALP00010011335.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416189", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416189", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RGF7-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member C18", "gene_name": "DNAJC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAATLGGGERWTEAYIDAVRRNKYPEDRPPESHDPCGCCNCMKAQSEKKPENEWTQTRQGEGNATYTEEQLLGVQRIKKCRNYYEILGVSRNASDEELKKAYRKLALKFHPDKNCAPGATDAFKAIGNAFAVLSNPDKRLRYDEYGDEQMTFTAPRARPYNYYRDFEADITPEELFNVFFGGHFPTGNIHMFSNVTDDTHYYRRRHRHERMQTRKEEEEDKPQTTYSAFIQLLPVLVIVIISVITQLLAANPPYSLFYKSTLGYTISRETQNLQVPYFVDKNFDKAYRGASLRDLEKTIEKDYIDYIQTSCWKEKQQKSELTNLAGLYRDERLKQKAESLKLENCEKLSKLLGLRRGG", "length": 358 }, "evidence": [ { "id": "E1C5R7", "url": "https://omabrowser.org/oma/group/E1C5R7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HVH7-1", "protein_name": "DnaJ homolog subfamily C member 18", "gene_name": "Dnajc18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAATLGSGERWTQAYIDAIRRNKYPEDRQPGSHDPCGCCNCMKAQKEKKSENEWNQTRQGEGSSTYTEEQLLGVQRIKKCRNYYEILGVSQNASDEELKKAYRKLALKFHPDKNCAPGATDAFKAIGNAFAVLSNPDKRLRYDEYGDEQMTFTAPRARSYHYYRDFEADISPEELFNVFFGGHFPSGNIHMFSNVTDDSHYYHRRHRHERTQTHKREEEDKPQTPYSAFVQLLPVLVIVVISVITQLLAANPPYSLFYKSTLGYTISRETQNLQVPYFVDKNFDKAYRGASLRDLEKTIEKDYIDYIQTSCWKEKQQKSELTNLAGLYRDERLRQKAESLKLENCEKLSKLIGLRRGG", "length": 358 }, "evidence": [ { "id": "E1C5R7", "url": "https://omabrowser.org/oma/group/E1C5R7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0H8V1-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member C18", "gene_name": "Dnajc18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATLGSGERWTQAYIDAIRRNKYPEDKQPDSHDPCGCCNCMKAQKEKKSENEWSQTRQGDGNATYTEEQLRGVQRIKKCRNYYDILGVSHNASDEELKKAYKKLALKFHPDKNCAPGATDAFKAIGNAFAVLSNPDKRLRYDEYGDEQVTLTAPRARPYHYYRDVEADISPEELFNVFFGGHFPSGNIHMFSNVTDDSHYYRRRHRHERTQAHKREEDKSQTPYSAFVQLLPVLLIVTISVITQLLAANPPYSLFYKSTLGYTISRETQNLQVPYFVDKNFDKAYRGASLRDLEKTIEKDYIDYIQTSCWKEKQQKSELTNLAGLYRDERLRQKAESLKLENCAKLSKLIGLRRAG", "length": 357 }, "evidence": [ { "id": "E1C5R7", "url": "https://omabrowser.org/oma/group/E1C5R7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5EA26-1", "protein_name": "DnaJ homolog subfamily C member 18", "gene_name": "DNAJC18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAATLGSGERWTEAYIDAVRRNKYPEDRPPESHDPCGCCNCMKGQKEKKSENEWSQTRQGEGNSTYTEEQLLGVQRIKKCRNYYEILGVSRDASDEELKKAYRKLALKFHPDKNCAPGATDAFKAIGNAFAVLSNPDKRLRYDEYGDEQVTFTAPRARPYNYYRDFETDITPEELFNVFFGGHFPTGNIHMFSNVTDDTHYYRRRHRHERMQTRKEEEEDKPQTTYSAFIQLLPVLVIVIISVITQLLAANPPYSLFYKSTLGHTISRETQNLQVPYFVDKNFDKAYRGASLRDLEKTIEKDYIDYIQTSCWKEKQQKSELTNLAGLYRDERLKQKAESLKLENCEKLSKLIGLRRGG", "length": 358 }, "evidence": [ { "id": "E1C5R7", "url": "https://omabrowser.org/oma/group/E1C5R7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CZJ9-1", "protein_name": "DnaJ homolog subfamily C member 18", "gene_name": "Dnajc18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTLGSGERWTQAYIDAIRRNKYPEDKRPDSHDPCGCCNCMKAQKEKKSENEWNQTRQGEGNATYTEEQLRGVQRIKKCRNYYDILGVSHNASDEELKKAYKKLALKFHPDKNCAPGATEAFKAIGNAFAVLSNPDKRLRYDEYGDEQVTFTVPRARSYHYYKDFEADISPEELFNVFFGGHFPSGNIHMFSNVTDDSQYYRRRHRHERTQTHKREEDKSQTPYSAFVQLLPVLVIVTISVITQLLAANPPYSLFYKSTLGYTISRETQNLQVPYFVDKNFDKAYRGASLRDLEKTIEKDYIDYIQTSCWKEKQQKSELTNLAGLYRDERLRQKAESLKLENCAKLSKLIGLRRAG", "length": 357 }, "evidence": [ { "id": "E1C5R7", "url": "https://omabrowser.org/oma/group/E1C5R7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFK2-1", "protein_name": "DNAJ heat shock N-terminal domain-containing protein", "gene_name": "MJJ3.16", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGNKDDALKCLKIGKDAIEAGDRSRALKFLEKARRLDPNLPIDGLVSDLKKQSDEPAAEEDSPGSAANESSKPSDRPSLRQRGSSSSAAGSSSSSSSTEEQRTIVREIKSKKDYYEILGLKSNCSVEDLRKSYRKLSLKVHPDKNKAPGSEEAFKSVSKAFQCLSNEDTRRKYDGSGSDEPAYQPRRDARRNNGFNGFYDDEFDADEIFRSFFGGGEMNPATTQFRSFNFGGGTRTANQASDTGFNPRVLLQILPVVFILLLNFLPSPQPIYSLSHRITTSSNSPRIGASLTL", "length": 294 }, "evidence": [ { "id": "E1C5R7", "url": "https://omabrowser.org/oma/group/E1C5R7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9H819-1", "protein_name": "DnaJ homolog subfamily C member 18", "gene_name": "DNAJC18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATLGSGERWTEAYIDAVRRNKYPEDTPPESHDPCGCCNCMKAQKEKKSENEWTQTRQGEGNSTYSEEQLLGVQRIKKCRNYYEILGVSRDASDEELKKAYRKLALKFHPDKNCAPGATDAFKAIGNAFAVLSNPDKRLRYDEYGDEQVTFTAPRARPYNYYRDFEADITPEELFNVFFGGHFPTGNIHMFSNVTDDTYYYRRRHRHERTQTQKEEEEEKPQTTYSAFIQLLPVLVIVIISVITQLLATNPPYSLFYKSTLGYTISRETQNLQVPYFVDKNFDKAYRGASLHDLEKTIEKDYIDYIQTSCWKEKQQKSELTNLAGLYRDERLKQKAESLKLENCEKLSKLIGLRRGG", "length": 358 }, "evidence": [ { "id": "E1C5R7", "url": "https://omabrowser.org/oma/group/E1C5R7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E1C5R7", "url": "https://www.uniprot.org/uniprotkb/E1C5R7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "E1C5R7", "url": "https://www.uniprot.org/uniprotkb/E1C5R7" } ], "pmid": "" }, { "name": "cellular response to misfolded protein", "id": "GO:0071218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071218", "evidence": [ { "database": "UniProtKB", "id": "E1C5R7", "url": "https://www.uniprot.org/uniprotkb/E1C5R7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "E1C5R7", "url": "https://www.uniprot.org/uniprotkb/E1C5R7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C5R7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 296, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C5R7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C5R7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C694-1", "uniprot_ac": "E1C694", "uniprot_id": "E1C694_CHICK", "mass": { "chemical_mass": 42649.0, "monoisotopic_mass": 42649.0 }, "refseq": { "ac": "XP_422345", "name": "epoxide hydrolase 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422345" }, "gene_names": [ { "name": "EPHX3", "type": "recommended", "evidence": [ { "id": "E1C694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C694" } ] }, { "name": "EPHX3", "type": "synonym", "evidence": [ { "id": "XP_422345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422345" } ] } ], "protein_names": [ { "name": "Epoxide hydrolase 3", "type": "synonym", "evidence": [ { "id": "E1C694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C694/entry#names_and_taxonomy" } ] }, { "name": "epoxide hydrolase 4", "type": "synonym", "evidence": [ { "id": "XP_422345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422345" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_422345.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422345" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C694", "url": "https://www.uniprot.org/uniprotkb/E1C694" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EPHX3", "url": "https://www.uniprot.org/uniprotkb/E1C694", "locus": {} } ], "crossref": [ { "id": "E1C694", "url": "https://alphafold.ebi.ac.uk/entry/E1C694", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006019", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006019", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424505", "url": "https://www.ncbi.nlm.nih.gov/gene/424505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424505", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424505", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRWMVRS", "url": "https://omabrowser.org/oma/group/YRWMVRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTX7", "url": "https://www.orthodb.org/?gene=A0A8V0ZTX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C694", "url": "https://www.orthodb.org/?gene=E1C694", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422345", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C694", "url": "https://www.uniprot.org/uniprotkb/E1C694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C694-1", "url": "https://www.uniprot.org/uniprotkb/E1C694-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPGAACQPPARRVMVAARALLFWALVYSYCGVCACIAGLRLLWSIGRRPGETFRWVMRENPPACLNDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGETDAPSHKENYKLDFLITDIKDILESLGYNKCVLIGHDWGGMIAWLVAICYPEMVTKLIVVNFPHPSVFTEYILRHPSQLIKSGYYFFFQMPWFPEFMFTVNDFKVLKSLFTSQTTGIGRKGCRLTAEDIEAYLYVFSQPGALTGPINHYRNIFSCLPLQHHEVIMPTLLLWGERDAFMEVEMAEITRIYVKNHFRLTILSEASHWLQQDQPDIVNKLIWTFLKEDTTRKRE", "length": 367, "header": "tr|E1C694-1|E1C694_CHICK Isoform 1 of Epoxide hydrolase 3 OS=Gallus gallus OX=9031 GN=EPHX3 PE=1 SV=4 CANONICAL=E1C694-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZTX7-1", "url": "https://www.uniprot.org/uniprotkb/E1C694/entry#A0A8V0ZTX7-1", "sequence": { "sequence": "MARPGAACQPPARRVMVAARALLFWALVYSYCGVCACIAGLRLLWSIGRRPGETFRWVMRENPPACLNDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGETDAPSHKENYKLDFLITDIKDILESLGYNKCVLIGHDWGGMIAWLVAICYPEMVTKLIVVNFPHPSVFTGSEKFIYQPDHWNREERMQINSRGY", "length": 230, "header": "tr|A0A8V0ZTX7-1|A0A8V0ZTX7_CHICK Computationally mapped isoform of Epoxide hydrolase 3 OS=Gallus gallus OX=9031 GN=EPHX3 PE=1 SV=1 CANONICAL=E1C694-1" }, "locus": { "chromosome": "8", "start_pos": 14024409, "end_pos": 14012675, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053602.1", "url": "https://www.ensembl.org/id/ENSGALT00010053602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032297.1", "url": "https://www.ensembl.org/id/ENSGALP00010032297.1" } ] } }, { "isoform_ac": "E1C694-1", "url": "https://www.uniprot.org/uniprotkb/E1C694/entry#E1C694-1", "sequence": { "sequence": "MARPGAACQPPARRVMVAARALLFWALVYSYCGVCACIAGLRLLWSIGRRPGETFRWVMRENPPACLNDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGETDAPSHKENYKLDFLITDIKDILESLGYNKCVLIGHDWGGMIAWLVAICYPEMVTKLIVVNFPHPSVFTEYILRHPSQLIKSGYYFFFQMPWFPEFMFTVNDFKVLKSLFTSQTTGIGRKGCRLTAEDIEAYLYVFSQPGALTGPINHYRNIFSCLPLQHHEVIMPTLLLWGERDAFMEVEMAEITRIYVKNHFRLTILSEASHWLQQDQPDIVNKLIWTFLKEDTTRKRE", "length": 367, "header": "tr|E1C694-1|E1C694_CHICK Isoform 1 of Epoxide hydrolase 3 OS=Gallus gallus OX=9031 GN=EPHX3 PE=1 SV=4 CANONICAL=E1C694-1" }, "locus": { "chromosome": "8", "start_pos": 14024409, "end_pos": 14008610, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053605.1", "url": "https://www.ensembl.org/id/ENSGALT00010053605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032298.1", "url": "https://www.ensembl.org/id/ENSGALP00010032298.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424505", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4ILH2-1", "protein_name": "Epoxide hydrolase 4", "gene_name": "ephx4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARLLHNLLLLTVGLTLKIRVMGYWSLIYGYCALCTGVALIKLGWNIILRPSTTFQWTVREIPPSCLNDTSLGTHCYVRIKESGLRFHYVAAGERGKPLMLFLHGFPEFWFSWRHQLREFKSEFRVVAVDMRGYGESDLPSSTESYRLDYLVTDIKDIVEYLGYNRCFLVGHDWGGIIAWLCAIHYPEMVTKLIVLNSPHPCVFTDYALRHPSQMLKSSYYFFFQLPYFPELMLSINDFKALKSLFTSRSTGISCKGRWLTTEDLEAYLYALSQPGALTGALNYFRNVFSVLPLSHSEVKSPVLLLWGERDAFLEQDMAEACRLYIRNLFRLNIISGASHWLQQDQPDIVNKLIWTFIKEGEGRKNYRNL", "length": 370 }, "evidence": [ { "id": "E1C694", "url": "https://omabrowser.org/oma/group/E1C694/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287AQU9-1", "protein_name": "Epoxide hydrolase 4", "gene_name": "EPHX4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPLRDRLPRLLVAIRSLLFWSLVYGYCGLCASFYLLKLLWSIGTGPTQTFRRAARDHPPAGLNDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSNYRVVALDLRGYGETDAPLHRENYKLDCLITDIKDILDFLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVLNFPHPNVFTEYILRHPAQLFKSSYYYFFQIPWFPEFMFSINDFKALRHLFTGHSTGTGRKGRPLTTEELEAYIYVFSQPGALSGPINHYRNIFSYLPLKHPMVITPTLLLWGEKDAFMEAEMAEVTKIYVQNYFRLTILSEASHWLQQEQPDIVNKLIWTFLKEETRKKD", "length": 362 }, "evidence": [ { "id": "E1C694", "url": "https://omabrowser.org/oma/group/E1C694/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1LVK8-1", "protein_name": "Epoxide hydrolase 4", "gene_name": "EPHX4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKLRDCLPRLMVTIRSLLFWCLIYFYCGLCSSIYLLKLLWSICKGPSQTFRRVAREHPPACLNDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGESDAPVHRENYKLDCLITDIKDILESLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINFPHPNVFTEYILRHPAQLFKSSYYYFFQIPWFPEFMFSINDFKALKHLFTSHSTGIGRKGCRLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVITPTLLLWGEKDAFMEVEMAEVTKIYVKNYFRLTILSETSHWLQQEQPDIVNKLIWTFLKEETRRKD", "length": 362 }, "evidence": [ { "id": "E1C694", "url": "https://omabrowser.org/oma/group/E1C694/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZKP8-1", "protein_name": "Epoxide hydrolase 4", "gene_name": "Ephx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPPRPPRLLPALRALLYWSLVYGYCGLCASVHLLKLLWSIGRAPAQTFRRAARANPPACLNDPSLGTHCYVRIKVKAVAGLETGEGEGRGWEPREPRCLGLRADYSSPDSCGHPEDPRGGRRDWAGGLFRARDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGESDAPIHQESYKLDCLIADIKDVLDSLGYNKCVLIGHDWGGMIAWLIAVCYPEMIMKLIVINFPHPSVFTEYILRHPAQLFRSSFYYFFQIPRLPELMFSINDFKALKHLFTSQSTGIGRKGRQLTTEDLEAYVYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGEEDAFMEVEMAEVTKIYVKNYFRLTILSEGSHWLQQDQPDIVNGLIWAFLREETRRD", "length": 417 }, "evidence": [ { "id": "E1C694", "url": "https://omabrowser.org/oma/group/E1C694/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IE26-1", "protein_name": "Epoxide hydrolase 4", "gene_name": "Ephx4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPPRPPRLLPALRALLYWSLVYGYCGLCASVHLLKLLWSIGRAPAQTFRRAARANPPACLNDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGESDAPAHQESYKLDCLIADIKDILDSLGYSKCVLIGHDWGGMIAWLIAVCYPEMIMKLIVINFPHPSVFTEYILRHPAQLFRSSFYYFFQIPRFPEFMFSINDFKALKHLFTSQSTGIGRKGRQLTTEDLEAYVYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGEEDAFMEVEMAEVTKIYVKNYFRLTILSEGSHWLQQDQPDIVNGLIWAFLKEETRRD", "length": 359 }, "evidence": [ { "id": "E1C694", "url": "https://omabrowser.org/oma/group/E1C694/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IUS5-1", "protein_name": "Epoxide hydrolase 4", "gene_name": "EPHX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLRDCLPRLMLTLRSLLFWSLVYCYCGLCASIHLLKLLWSLGKGPAQTFRRPAREHPPACLSDPSLGTHCYVRIKDSGLRFHYVAAGERGKPLMLLLHGFPEFWYSWRYQLREFKSEYRVVALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVMKLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKHLFTSHSTGIGRKGCQLTTEDLEAYIYVFSQPGALSGPINHYRNIFSCLPLKHHMVTTPTLLLWGENDAFMEVEMAEVTKIYVKNYFRLTILSEASHWLQQDQPDIVNKLIWTFLKEETRKKD", "length": 362 }, "evidence": [ { "id": "E1C694", "url": "https://omabrowser.org/oma/group/E1C694/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "E1C694", "url": "https://www.uniprot.org/uniprotkb/E1C694" } ], "pmid": "" }, { "name": "epoxide hydrolase activity", "id": "GO:0004301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004301", "evidence": [ { 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The reference sequence was derived from DR410918.1, AL585240.1, AM069835.1, BX950653.1 and BU350883.1. 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protein 1", "type": "synonym", "evidence": [ { "id": "NP_001186459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186459" } ] }, { "name": "J domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "E1C6F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6F1/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily C member 12", "type": "synonym", "evidence": [ { "id": "NP_001186459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186459" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01007272.1, HAEK01000114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000227.1. On Dec 12, 2010 this sequence version replaced XP_421530.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186459" } ] }, { "annotation": "Probable co-chaperone that participates in the proper folding of biopterin-dependent aromatic amino acid hydroxylases, which include phenylalanine-4-hydroxylase (PAH), tyrosine 3-monooxygenase (TH) and peripheral and neuronal tryptophan hydroxylases (TPH1 and TPH2).", "evidence": [ { "database": "UniProtKB", "id": "E1C6F1", "url": "https://www.uniprot.org/uniprotkb/E1C6F1#function" }, { "database": "UniProtKB", "id": "ARBA00053379", "url": "https://www.uniprot.org/uniprotkb/ARBA00053379#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6F1", "url": "https://www.uniprot.org/uniprotkb/E1C6F1" } ], 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"Protein Classification" ] }, { "id": "PTHR44500:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44500:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186459", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C6F1", "url": "https://www.uniprot.org/uniprotkb/E1C6F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6F1-1", "url": "https://www.uniprot.org/uniprotkb/E1C6F1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAILNCRLDELEDYYNLLGCDELSTVEQILAEFKIKALECHPDKHPGNPKAVENFQKLQQAKEVLIHEESRARYDYWRRSKITIPFQEWEALSSSVKTSMHWAVQNKKDQMLEAPDLNNSNNLTNEIWTQKTENDEDGLSDGNREQDVAIPDVKPQSSKNPDSPRFSEANYWHLRFRWSGDAPSDLLRKFRNYEI", "length": 196, "header": "tr|E1C6F1-1|E1C6F1_CHICK Isoform 1 of DnaJ homolog subfamily C member 12 OS=Gallus gallus OX=9031 GN=DNAJC12 PE=4 SV=1 CANONICAL=E1C6F1-1" }, "isoforms": [ { "isoform_ac": "E1C6F1-1", "url": "https://www.uniprot.org/uniprotkb/E1C6F1/entry#E1C6F1-1", "sequence": { "sequence": "MDAILNCRLDELEDYYNLLGCDELSTVEQILAEFKIKALECHPDKHPGNPKAVENFQKLQQAKEVLIHEESRARYDYWRRSKITIPFQEWEALSSSVKTSMHWAVQNKKDQMLEAPDLNNSNNLTNEIWTQKTENDEDGLSDGNREQDVAIPDVKPQSSKNPDSPRFSEANYWHLRFRWSGDAPSDLLRKFRNYEI", "length": 196, "header": "tr|E1C6F1-1|E1C6F1_CHICK Isoform 1 of DnaJ homolog subfamily C member 12 OS=Gallus gallus OX=9031 GN=DNAJC12 PE=4 SV=1 CANONICAL=E1C6F1-1" }, "locus": { "chromosome": "6", "start_pos": 7337606, "end_pos": 7329884, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010022062.1", "url": "https://www.ensembl.org/id/ENSGALT00010022062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010012652.1", "url": "https://www.ensembl.org/id/ENSGALP00010012652.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423647", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423647", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F5S9-1", "protein_name": "DnaJ homolog subfamily C member 12", "gene_name": "dnajc12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAILNCRKEDLEDYYGLLGCDELSTTEQIVNEFKVKALACHPDKHPENPKAVEQFQKLQEAKEVLTDEKKRKSYDLWLRSQIKIPFGEWRALSDSVKTSMHWAVKAKKEPMLEAAEDSNPSDENTVQEKPSEASLPSSDYWHQRFRWAGEAPTGLLQKFRNYEI", "length": 165 }, "evidence": [ { "id": "E1C6F1", "url": "https://omabrowser.org/oma/group/E1C6F1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HAB2-1", "protein_name": "DnaJ homolog subfamily C member 12", "gene_name": "Dnajc12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDAILNYRPEGTEDYYALLGCDELSSVEQILAEFKVRALECHPDKHPENSKAVETFQKLQKAKEILTNAESRARYDHWRRSQMSMPFEQWDALADSVKTSMHWAVRSKKDLMLEGMDQTYTNTVQNKEQNEQRETKKGEPDSTTEKTRQKESGSPEKAIAPQNPGSPDLNCGHLRFRWSGDPPSELLRKFRNYEI", "length": 195 }, "evidence": [ { "id": "E1C6F1", "url": "https://omabrowser.org/oma/group/E1C6F1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q925T0-1", "protein_name": "DnaJ homolog subfamily C member 12", "gene_name": "Dnajc12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAILNYRPEGSEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENSKAVETFQKLQKAKEILSNAESRARYDHWRRSQMSMSFEQWEALADSVKTSMHWAVRSKKDLMLEGSEQTYTNTAQNKERSEQRETKQGDPDSTPEKMMQKESESPEKGISPQNPDSPGLSDWNCGHLHFRWSGDTPSELLRKFRNYEI", "length": 198 }, "evidence": [ { "id": "E1C6F1", "url": "https://omabrowser.org/oma/group/E1C6F1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9N287-1", "protein_name": "DnaJ homolog subfamily C member 12", "gene_name": "DNAJC12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAILNYKSEDTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENSKAVETFQKLQKAKDILTNEASRARYDHWRRSQMSMSFQQWEALSDSVKMSMHWAVRGKKDLMLEESDQTPTDKIENEEQDEQKEIKKEEFGSTTEKMEQKESKSVEKSFSPQNPDSPGFANVNCWHLRFRWSGDAPSELLRKFRNYEI", "length": 198 }, "evidence": [ { "id": "E1C6F1", "url": "https://omabrowser.org/oma/group/E1C6F1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9R022-1", "protein_name": "DnaJ homolog subfamily C member 12", "gene_name": "Dnajc12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAILNYRPEGSEDYYALLGCDELSSVEQILAEFKIRALECHPDKHPENSKAVETFQKLQKAKEILCNAESRARYDHWRRSQMSMPFEQWEALADSVKTSMHWAVRSKKDLMLEGSGQTFTSSVPNKERSEQRETKKGDPDSNPEKMKQKEPKFPEEGISPQNPDSPGLSDLNCGHLRFRWSGDAPSELLRKFRNYEI", "length": 198 }, "evidence": [ { "id": "E1C6F1", "url": "https://omabrowser.org/oma/group/E1C6F1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9TVP3-1", "protein_name": "J domain-containing protein", "gene_name": "jdp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAVDAIINYKRSPNEDFYGLLHCDENSSPEQIQAEYKVLALQYHPDKNSGDKEAEAKFQQLKEAKETLCDPEKRAIYDKWRNSGISMSYKQWLGMKEHVGQVRRYTIAEKVDKESMHWVTPKTKDRMLPETGGAAAQGPGTGAGCSSGGLTAASPNPAHRRASEGGAALYYGSRKGEWGGENTDVANKFRNYEI", "length": 195 }, "evidence": [ { "id": "E1C6F1", "url": "https://omabrowser.org/oma/group/E1C6F1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9UKB3-1", "protein_name": "DnaJ homolog subfamily C member 12", "gene_name": "DNAJC12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C6G2-1", "uniprot_ac": "E1C6G2", "uniprot_id": "E1C6G2_CHICK", "mass": { "chemical_mass": 84620.0, "monoisotopic_mass": 84620.0 }, "refseq": { "ac": "XP_015139293", "name": "leucine-rich repeat and fibronectin type-III domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139293" }, "gene_names": [ { "name": "LRFN2", "type": "recommended", "evidence": [ { "id": "E1C6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ] }, { "name": "LRFN2", "type": "synonym", "evidence": [ { "id": "XP_015139293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139293" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "E1C6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6G2/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat and fibronectin type-III domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_015139293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139293" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139293" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRFN2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2", "locus": { "chromosome": "3", "start_pos": 28066818, "end_pos": 27921235, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020095", "url": "https://www.ensembl.org/id/ENSGALG00010020095" } ] } } ], "crossref": [ { "id": "E1C6G2", "url": "https://alphafold.ebi.ac.uk/entry/E1C6G2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010050", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010050", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05764", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05764", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428571", "url": "https://www.ncbi.nlm.nih.gov/gene/428571", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428571", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428571", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELMDFSA", "url": "https://omabrowser.org/oma/group/ELMDFSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C6G2", "url": "https://www.orthodb.org/?gene=E1C6G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8849932", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849932", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015139293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6G2-1", "url": "https://www.uniprot.org/uniprotkb/E1C6G2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKLLCGILVFGMAVMVNACPKYCVCQNLSESLGTLCPSKGLLFVPLDIDRRTVELRLGGNFIINISRQDFANMSGLVDLTLSRNTISYIQPYSFTDLESLRSLHLDSNRLPDIGEDILRGLINLQHLILNNNQLTSISDEAFEDFLLTLEDLDLSYNNLRSIPWESIRKMINLHQLSLDHNLIDYITEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQVIPLAVTPFSPPLSLSFGGNPLHCNCELLWLRRLDRDDDMETCASPPGLKGRYFWYVREEEFVCEPPLITQHTHKLLVLEGQTATLKCKAIGDPTPIIHWVAPDDRLIGNSSRTSVYDNGTLDILITTSKDYGTFTCIAANAAGESTATIELSIVQLPHLSNGTGRAAPPKSRLSDITSSSKSNRGETKGPPERAVLVSEVTTTSALVKWTVSKSAPRVKMYQLQYNCSDDEVLIYRMIPATNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKEDYPQCQSMHSHFLGGTMILIIGGIIVATLLVFIVILMVRYKVCNNSQGKMSSVSNVYSQTNGAQPVQNGVLPQVNPKVVVRNELMEFNSGSVRSSISSSSSSMNSRDCDNYSLQSEQGTLSSKWRPPSRSKHNIDRLMGAFASLELKCQKKEETTDSRTSTAARHSDKEPLLGQPESKFRSLLMLPLEGKTKRSHSFDMGDFATSQCCTYPKKITNIWTKRSLSVNGMLLQYDDNDLTGAKGTYGSSEWVMESTV", "length": 763, "header": "tr|E1C6G2-1|E1C6G2_CHICK Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Gallus gallus OX=9031 GN=LRFN2 PE=3 SV=4 CANONICAL=E1C6G2-1" }, "isoforms": [ { "isoform_ac": "E1C6G2-1", "url": "https://www.uniprot.org/uniprotkb/E1C6G2/entry#E1C6G2-1", "sequence": { "sequence": "MEKLLCGILVFGMAVMVNACPKYCVCQNLSESLGTLCPSKGLLFVPLDIDRRTVELRLGGNFIINISRQDFANMSGLVDLTLSRNTISYIQPYSFTDLESLRSLHLDSNRLPDIGEDILRGLINLQHLILNNNQLTSISDEAFEDFLLTLEDLDLSYNNLRSIPWESIRKMINLHQLSLDHNLIDYITEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQVIPLAVTPFSPPLSLSFGGNPLHCNCELLWLRRLDRDDDMETCASPPGLKGRYFWYVREEEFVCEPPLITQHTHKLLVLEGQTATLKCKAIGDPTPIIHWVAPDDRLIGNSSRTSVYDNGTLDILITTSKDYGTFTCIAANAAGESTATIELSIVQLPHLSNGTGRAAPPKSRLSDITSSSKSNRGETKGPPERAVLVSEVTTTSALVKWTVSKSAPRVKMYQLQYNCSDDEVLIYRMIPATNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKEDYPQCQSMHSHFLGGTMILIIGGIIVATLLVFIVILMVRYKVCNNSQGKMSSVSNVYSQTNGAQPVQNGVLPQVNPKVVVRNELMEFNSGSVRSSISSSSSSMNSRDCDNYSLQSEQGTLSSKWRPPSRSKHNIDRLMGAFASLELKCQKKEETTDSRTSTAARHSDKEPLLGQPESKFRSLLMLPLEGKTKRSHSFDMGDFATSQCCTYPKKITNIWTKRSLSVNGMLLQYDDNDLTGAKGTYGSSEWVMESTV", "length": 763, "header": "tr|E1C6G2-1|E1C6G2_CHICK Isoform 1 of Leucine-rich repeat and fibronectin type-III domain-containing protein 2 OS=Gallus gallus OX=9031 GN=LRFN2 PE=3 SV=4 CANONICAL=E1C6G2-1" }, "locus": { "chromosome": "3", "start_pos": 28066297, "end_pos": 28029172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048534.1", "url": "https://www.ensembl.org/id/ENSGALT00010048534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028625.1", "url": "https://www.ensembl.org/id/ENSGALP00010028625.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428571", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428571", "resource": "KEGG Pathway" }, { "id": "R-GGA-8849932", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8849932", "resource": "Reactome", "description": "Synaptic adhesion-like molecules" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BDP0-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIAEEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMINLHQLSLDHNLLDHIAEGTFTDLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRAAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYTQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNQEGTGKPAAAVTNVHSQTNGAQPPALGSVPSGAPVPGPPKVVVRNELMDFSASLARGSDSSSSSSLGIGEGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSAKGHPSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAATGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESGLVGARGTFGSSEWVMESTV", "length": 787 }, "evidence": [ { "id": "E1C6G2", "url": "https://omabrowser.org/oma/group/E1C6G2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RVP3-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWGSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKAGDPQCQSMHSQILGGTVILVIGGTIVATLLVFIVILMVRYKVCNQEAPGKTAATVSNTHSQTNGAQPPAPSSTPSGAPVPGPPKAVVRNELVEFSASLARGSDSSSSSSLGFGEALGLGRGPWRLPPPAPRPKPNLDRLMGAFASLDLKSQRKEELLDSRTPGGRGSGTSARVHPSDREPLLGPPTARARSLLPLPLEGKAKRSHSFDMGDFAAAASAVGGVAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 791 }, "evidence": [ { "id": "E1C6G2", "url": "https://omabrowser.org/oma/group/E1C6G2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I1G3-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPNPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGAFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSAPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILIIGGIIVATLLVFIVILMVRYKVCNHDAPGKMAAATVSNVYSQTNGAQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAVAAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "E1C6G2", "url": "https://omabrowser.org/oma/group/E1C6G2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q460M5-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLKTCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDAPGKMAAATVSNVYSQTNGAQPPPLGGMPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAAPGGYSPPRRVSNIWTKRSLSVNGMLLPFEENDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "E1C6G2", "url": "https://omabrowser.org/oma/group/E1C6G2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TG9-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "Lrfn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGSLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHDTPGKMAAATVSNVYSQTNGSQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLGRGPWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSSRGHHSDREPLLGPPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAAAVPGGYSPPRRVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 788 }, "evidence": [ { "id": "E1C6G2", "url": "https://omabrowser.org/oma/group/E1C6G2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULH4-1", "protein_name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "gene_name": "LRFN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRAPWRIPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV", "length": 789 }, "evidence": [ { "id": "E1C6G2", "url": "https://omabrowser.org/oma/group/E1C6G2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "E1C6G2", "url": "https://www.uniprot.org/uniprotkb/E1C6G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C6G2-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 763, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C6G2-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C6G2" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 618, "end_pos": 620 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E1C6J5-1", "uniprot_ac": "E1C6J5", "uniprot_id": "E1C6J5_CHICK", "mass": { "chemical_mass": 38124.0, "monoisotopic_mass": 38124.0 }, "refseq": { "ac": "XP_040559669", "name": "cytohesin-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559669" }, "gene_names": [ { "name": "CYTIP", "type": "recommended", "evidence": [ { "id": "E1C6J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ] }, { "name": "CYTIP", "type": "synonym", "evidence": [ { "id": "XP_040559669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559669" } ] } ], "protein_names": [ { "name": "Cytohesin 1 interacting protein", "type": "synonym", "evidence": [ { "id": "E1C6J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6J5/entry#names_and_taxonomy" } ] }, { "name": "cytohesin-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040559669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559669" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040559669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559669" } ] }, { "annotation": "Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.", "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5#function" }, { "database": "UniProtKB", "id": "ARBA00058705", "url": "https://www.uniprot.org/uniprotkb/ARBA00058705#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYTIP", "url": "https://www.uniprot.org/uniprotkb/E1C6J5", "locus": { "chromosome": "7", "start_pos": 35829467, "end_pos": 35838264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010010586", "url": "https://www.ensembl.org/id/ENSGALG00010010586" } ] } } ], "crossref": [ { "id": "E1C6J5", "url": "https://alphafold.ebi.ac.uk/entry/E1C6J5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012545", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06713", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06713", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429052", "url": "https://www.ncbi.nlm.nih.gov/gene/429052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SVRKHIF", "url": "https://omabrowser.org/oma/group/SVRKHIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E1C6J5", "url": "https://www.orthodb.org/?gene=E1C6J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15963:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15963:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040559669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C6J5-1", "url": "https://www.uniprot.org/uniprotkb/E1C6J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVRRLAQHGQRSGTGDRGVQMDGRRLQQLVSTVGTLPRSRKQLALTRSSSLGDCSRPQRHFISIFKEDKETFGFEIQTIRFPNQTDYSLEACTCVCKIQEESPAHFSGLQIGDILANVNGVNTDGFSHKQIVDLIKSSGNYLRLETVNGALFLRKMELETKLQLLKQTLQQKWVELRSLHLQEQRLLHGEVNDNALLELEEANLFGDCTPGPLSPTKTRFSSESSSRSRLSSMTLDSEDSFYQSGAFDDSAAESLSRQSSMDDDCFLPRDGDGTAGRCSLRRHRSISLASSGSMSPLWESGGSSSSFGTLPRKSRRSSVRKQLLKFIPGLHRALEEEESRV", "length": 342, "header": "tr|E1C6J5-1|E1C6J5_CHICK Isoform 1 of Cytohesin 1 interacting protein OS=Gallus gallus OX=9031 GN=CYTIP PE=4 SV=2 CANONICAL=E1C6J5-1" }, "isoforms": [ { "isoform_ac": "E1C6J5-1", "url": "https://www.uniprot.org/uniprotkb/E1C6J5/entry#E1C6J5-1", "sequence": { "sequence": "MSVRRLAQHGQRSGTGDRGVQMDGRRLQQLVSTVGTLPRSRKQLALTRSSSLGDCSRPQRHFISIFKEDKETFGFEIQTIRFPNQTDYSLEACTCVCKIQEESPAHFSGLQIGDILANVNGVNTDGFSHKQIVDLIKSSGNYLRLETVNGALFLRKMELETKLQLLKQTLQQKWVELRSLHLQEQRLLHGEVNDNALLELEEANLFGDCTPGPLSPTKTRFSSESSSRSRLSSMTLDSEDSFYQSGAFDDSAAESLSRQSSMDDDCFLPRDGDGTAGRCSLRRHRSISLASSGSMSPLWESGGSSSSFGTLPRKSRRSSVRKQLLKFIPGLHRALEEEESRV", "length": 342, "header": "tr|E1C6J5-1|E1C6J5_CHICK Isoform 1 of Cytohesin 1 interacting protein OS=Gallus gallus OX=9031 GN=CYTIP PE=4 SV=2 CANONICAL=E1C6J5-1" }, "locus": { "chromosome": "7", "start_pos": 35838181, "end_pos": 35829769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010025202.1", "url": "https://www.ensembl.org/id/ENSGALT00010025202.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014285.1", "url": "https://www.ensembl.org/id/ENSGALP00010014285.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E7F4K6-1", "protein_name": "Cytohesin-interacting protein", "gene_name": "cytip", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMTSNRNFKMPLKQMSSLDSYIIDSSQKKRSILWRQRSFSSPKNLNTEGMKGRTLSQSQLARTHSNSLVDYTDPQRTMVVLEKQDNEVFGFEVQTYGLKVKNTSMVEMCTFVCRVQDGSAAETAGLTAGDIILSVNGVSIEGSTHQNIIELIRESSNTLKLETVSGSVMKRIELEKKMHYLKQTLREKWVELQSLTLKEKRLTQGNLNESAQYLSVDSVMSLSSPMGRSGQRFSSDSSCRSIMTDDSEDGAFMSSVFDDSSPLSPIESSGSFFQLEVGALRPITRTRSISLTGSNSSLSPGWETSPSSLFGTLPRRSRKGSVRKHLLKFIPGLNHSVEEEECS", "length": 343 }, "evidence": [ { "id": "E1C6J5", "url": "https://omabrowser.org/oma/group/E1C6J5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HHT5-1", "protein_name": "Cytohesin-interacting protein", "gene_name": "Cytip", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLQRLLQHQNGNGNLEYYVDSSYSSYSTLTGPLTMEDSRRVQMLADTVATLPRGRKQLALARSSSLGDFSWSQRKLVTVEKQDNGAFGFEIQTYRLQNQNICSSEICTMICKVQEDSPAHCAGLQAGDILANINGVSTEGFTHKQVVDLIRSSGNLLTIETLNGAMIHRRAELEAKLQALKQTLKKKWVEFRSLHLQEQRLLHGDAANSPNLENMDLDELSLFGNLLGPGPALLDRNRLSSESSCKSRLSSVTMDSEDGYRTSVSEDSSRGAFSRQTSTDDECFLSKDGDDILRNAASRRNRSISVTSNGSLSPLWEGNYSSMFGTLPRKSRRGSVRKQILKFIPGLHRAVEEEESRF", "length": 359 }, "evidence": [ { "id": "E1C6J5", "url": "https://omabrowser.org/oma/group/E1C6J5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60759-1", "protein_name": "Cytohesin-interacting protein", "gene_name": "CYTIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSRRNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF", "length": 359 }, "evidence": [ { "id": "E1C6J5", "url": "https://omabrowser.org/oma/group/E1C6J5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0L6-1", "protein_name": "Cytohesin-interacting protein", "gene_name": "Cytip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLQRLLQQQSSNGNLEYCADSAYSSYPTLTGPLTVEDNRRIQMLADTVATLPRGRKQLALARSSSLGDFSCSQRKVVTVEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPAHCAGLQVGDIFANVNGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMIHRRAELEAKLQTLKQTLKKKWVELRSLHLQEQRLLHGDAANSPNLENMNLDESSLFGNLLGPSPAFLDRPRLSSESSCKSWLSSLTVDSEDDYGTSVSEDSIRGAFSRQTSTDDECFHSKDGDEILRNASSRRNRSISITSSGSFSPLWESNYSSVFGTLPRKSRRGSVRKQILKFIPGLHRAVEEEESRF", "length": 359 }, "evidence": [ { "id": "E1C6J5", "url": "https://omabrowser.org/oma/group/E1C6J5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91VY6-1", "protein_name": "Cytohesin-interacting protein", "gene_name": "Cytip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLQRFLQRQGSNGNLEYCADSAYGSYSVLTGQLTMEDNRRIQVLADTVATLPRGRKQLALARSSSLGDFSWSQRKVVTVEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPAHCAGLQVGDIFANVNGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMIHRRAELEAKLQTLKQTLKKKWVELRSLHLQEQRLLHGDTANSPNLENMDLDESSLFGNLLGPSPALLDRHRLSSESSCKSWLSSLTVDSEDGYRSSMSEDSIRGAFSRQTSTDDECFHSKDGDEILRNASSRRNRSISVTSSGSFSPLWESNYSSVFGTLPRKSRRGSVRKQILKFIPGLHRAVEEEESRF", "length": 359 }, "evidence": [ { "id": "E1C6J5", "url": "https://omabrowser.org/oma/group/E1C6J5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell adhesion", "id": "GO:0030155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030155", "evidence": [ { "database": "UniProtKB", "id": "E1C6J5", "url": "https://www.uniprot.org/uniprotkb/E1C6J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-E1C6J5-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 342, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-E1C6J5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/E1C6J5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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This record is derived from a genomic sequence (NC_052572.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642980", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642980" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "E1C6T0", "url": "https://www.uniprot.org/uniprotkb/E1C6T0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLCXD3", "url": "https://www.uniprot.org/uniprotkb/E1C6T0", "locus": { "chromosome": "Z", "start_pos": 13552823, "end_pos": 13643023, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010012497", "url": "https://www.ensembl.org/id/ENSGALG00010012497" } ] } } ], "crossref": [ { "id": "E1C6T0", "url": "https://alphafold.ebi.ac.uk/entry/E1C6T0", "database": "AlphaFoldDB", 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